Vivien R. Sutton

Publications

• Granzyme H is a Novel Protease Expressed by Human Mast Cells
  International Archives of Allergy and Immunology. 2014  |   Pubmed ID: 25342632
• Perforin Forms Transient Pores on the Target Cell Plasma Membrane to Facilitate Rapid Access of Granzymes During Killer Cell Attack
  Blood. Apr, 2013  |   Pubmed ID: 23377437
• A Novel Role for Granzymes in Anti-tumor Immunity
  Oncoimmunology. Mar, 2012  |   Pubmed ID: 22720248
• Activated Mouse B Cells Lack Expression of Granzyme B
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2012  |   Pubmed ID: 22427643
• A Critical Role for Granzymes in Antigen Cross-presentation Through Regulating Phagocytosis of Killed Tumor Cells
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2011  |   Pubmed ID: 21709155
• Cathepsin C Limits Acute Viral Infection Independently of NK Cell and CD8+ T-cell Cytolytic Function
  Immunology and Cell Biology. May, 2011  |   Pubmed ID: 20975734
• Proteases in Lymphocyte Killer Function: Redundancy, Polymorphism and Questions Remaining
  Biological Chemistry. Aug, 2010  |   Pubmed ID: 20731542
• Human and Mouse Perforin Are Processed in Part Through Cleavage by the Lysosomal Cysteine Proteinase Cathepsin L
  Immunology. Oct, 2010  |   Pubmed ID: 20497254
• Cathepsin H is an Additional Convertase of Pro-granzyme B
  The Journal of Biological Chemistry. Jul, 2010  |   Pubmed ID: 20435891
• Dihydrofuro[3,4-c]pyridinones As Inhibitors of the Cytolytic Effects of the Pore-forming Glycoprotein Perforin
  Journal of Medicinal Chemistry. Dec, 2008  |   Pubmed ID: 19007200
• Measuring Cell Death Mediated by Cytotoxic Lymphocytes or Their Granule Effector Molecules
  Methods (San Diego, Calif.). Mar, 2008  |   Pubmed ID: 18314055
• Perforin Activity and Immune Homeostasis: the Common A91V Polymorphism in Perforin Results in Both Presynaptic and Postsynaptic Defects in Function
  Blood. Aug, 2007  |   Pubmed ID: 17475905
• Residual Active Granzyme B in Cathepsin C-null Lymphocytes is Sufficient for Perforin-dependent Target Cell Apoptosis
  The Journal of Cell Biology. Feb, 2007  |   Pubmed ID: 17283185
• Granzyme B-mediated Death of Pancreatic Beta-cells Requires the Proapoptotic BH3-only Molecule Bid
  Diabetes. Aug, 2006  |   Pubmed ID: 16873683
• Cytotoxic T Lymphocyte-induced Killing in the Absence of Granzymes A and B is Unique and Distinct from Both Apoptosis and Perforin-dependent Lysis
  The Journal of Cell Biology. Apr, 2006  |   Pubmed ID: 16606695
• A Critical Role for Granzyme B, in Addition to Perforin and TNFalpha, in Alloreactive CTL-induced Mouse Pancreatic Beta Cell Death
  Transplantation. Jan, 2006  |   Pubmed ID: 16436955
• A Central Role for Bid in Granzyme B-induced Apoptosis
  The Journal of Biological Chemistry. Feb, 2005  |   Pubmed ID: 15574417
• Granzyme B: Pro-apoptotic, Antiviral and Antitumor Functions
  Current Opinion in Immunology. Oct, 2003  |   Pubmed ID: 14499262
• Purification of Natural Killer Cell Cytotoxic Granules for Assaying Target Cell Apoptosis
  Journal of Immunological Methods. May, 2003  |   Pubmed ID: 12738359
• Caspase Activation by Granzyme B is Indirect, and Caspase Autoprocessing Requires the Release of Proapoptotic Mitochondrial Factors
  Immunity. Mar, 2003  |   Pubmed ID: 12648450
• A Clathrin/dynamin- and Mannose-6-phosphate Receptor-independent Pathway for Granzyme B-induced Cell Death
  The Journal of Cell Biology. Jan, 2003  |   Pubmed ID: 12538642