Weibin Chen

Publications

• The Characterization of Drug-to-Antibody Ratio and Isoforms of ADCs Using LC and MS Technologies
  Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 2017  |   Pubmed ID: 28458283
• In-depth Structural Characterization of Kadcyla® (ado-trastuzumab Emtansine) and Its Biosimilar Candidate
  MAbs. 10, 2016  |   Pubmed ID: 27380163
• Advanced Assessment of the Physicochemical Characteristics of Remicade® and Inflectra® by Sensitive LC/MS Techniques
  MAbs. Aug-Sep, 2016  |   Pubmed ID: 27260215
• A Sensitive Multidimensional Method for the Detection, Characterization, and Quantification of Trace Free Drug Species in Antibody-drug Conjugate Samples Using Mass Spectral Detection
  MAbs. 2016  |   Pubmed ID: 26651262
• A Rapid On-line Method for Mass Spectrometric Confirmation of a Cysteine-conjugated Antibody-drug-conjugate Structure Using Multidimensional Chromatography
  MAbs. 2015  |   Pubmed ID: 26305867
• Enhanced Detection of Low-Abundance Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 Ppm Using Ion Mobility Mass Spectrometry Coupled with Multidimensional Liquid Chromatography
  Analytical Chemistry. Oct, 2015  |   Pubmed ID: 26266576
• Analysis of Host-cell Proteins in Biotherapeutic Proteins by LC/MS Approaches
  Methods in Molecular Biology (Clifton, N.J.). 2014  |   Pubmed ID: 24648086
• N- and O-glycosylation Analysis of Etanercept Using Liquid Chromatography and Quadrupole Time-of-flight Mass Spectrometry Equipped with Electron-transfer Dissociation Functionality
  Analytical Chemistry. Jan, 2014  |   Pubmed ID: 24308717
• Characterisation of Glycoproteins Using a Quadrupole Time-of-flight Mass Spectrometer Configured for Electron Transfer Dissociation
  Rapid Communications in Mass Spectrometry : RCM. Nov, 2013  |   Pubmed ID: 24097394
• Analysis of Host-cell Proteins in Biotherapeutic Proteins by Comprehensive Online Two-dimensional Liquid Chromatography/mass Spectrometry
  MAbs. Jan-Feb, 2012  |   Pubmed ID: 22327428
• Characterization of a Recombinant Influenza Vaccine Candidate Using Complementary LC-MS Methods
  Current Pharmaceutical Biotechnology. Oct, 2011  |   Pubmed ID: 21542793
• Rapid Comparison of a Candidate Biosimilar to an Innovator Monoclonal Antibody with Advanced Liquid Chromatography and Mass Spectrometry Technologies
  MAbs. Jul-Aug, 2010  |   Pubmed ID: 20458189
• Analysis of Oligosaccharides Derived from Heparin by Ion-pair Reversed-phase Chromatography/mass Spectrometry
  Analytical Chemistry. May, 2009  |   Pubmed ID: 19344114
• Determination of N-glycosylation Sites and Site Heterogeneity in a Monoclonal Antibody by Electrospray Quadrupole Ion-mobility Time-of-flight Mass Spectrometry
  Rapid Communications in Mass Spectrometry : RCM. 2008  |   Pubmed ID: 18050193
• Improving De Novo Sequencing of Peptides Using a Charged Tag and C-terminal Digestion
  Analytical Chemistry. Feb, 2007  |   Pubmed ID: 17297959
• Qualitative and Quantitative Analysis of Small Amine Molecules by MALDI-TOF Mass Spectrometry Through Charge Derivatization
  Analytical Chemistry. Aug, 2004  |   Pubmed ID: 15307802