Wenbiao Chen Department of Molecular Physiology and Biophysics Vanderbilt University Biography Publications Institution JoVE Articles Wenbiao Chen has not added a biography. If you are Wenbiao Chen and would like to personalize this page please email our Author Liaison for assistance. Publications Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation Cell Metabolism. Jun, 2017 | Pubmed ID: 28591638 Modeling Pancreatic Endocrine Cell Adaptation and Diabetes in the Zebrafish Frontiers in Endocrinology. 2017 | Pubmed ID: 28184214 Autolysosome Biogenesis and Developmental Senescence Are Regulated by Both Spns1 and V-ATPase Autophagy. Feb, 2017 | Pubmed ID: 27875093 Zebrafish Genome Engineering Using the CRISPR-Cas9 System Trends in Genetics : TIG. Dec, 2016 | Pubmed ID: 27836208 Leptin Signaling Regulates Glucose Homeostasis, but Not Adipostasis, in the Zebrafish Proceedings of the National Academy of Sciences of the United States of America. Mar, 2016 | Pubmed ID: 26903647 Active Medulloblastoma Enhancers Reveal Subgroup-specific Cellular Origins Nature. Feb, 2016 | Pubmed ID: 26814967 FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation Diabetes. Jan, 2016 | Pubmed ID: 26420862 Insulin-mediated Signaling Promotes Proliferation and Survival of Glioblastoma Through Akt Activation Neuro-oncology. Jan, 2016 | Pubmed ID: 26136493 Glucagon Receptor Inactivation Leads to α-cell Hyperplasia in Zebrafish The Journal of Endocrinology. Nov, 2015 | Pubmed ID: 26446275 Generation of Targeted Mutations in Zebrafish Using the CRISPR/Cas System Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26285757 A Conserved Role of αA-crystallin in the Development of the Zebrafish Embryonic Lens Experimental Eye Research. Sep, 2015 | Pubmed ID: 26149094 High-throughput Gene Targeting and Phenotyping in Zebrafish Using CRISPR/Cas9 Genome Research. Jul, 2015 | Pubmed ID: 26048245 Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and SgRNAs Genetics. Jun, 2015 | Pubmed ID: 25855067 Circadian Modulation of Dopamine Levels and Dopaminergic Neuron Development Contributes to Attention Deficiency and Hyperactive Behavior The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2015 | Pubmed ID: 25673850 Skeletal Muscle Insulin Resistance in Zebrafish Induces Alterations in β-cell Number and Glucose Tolerance in an Age- and Diet-dependent Manner American Journal of Physiology. Endocrinology and Metabolism. Apr, 2015 | Pubmed ID: 25670827 Oncogenic KRAS Promotes Malignant Brain Tumors in Zebrafish Molecular Cancer. Feb, 2015 | Pubmed ID: 25644510 Spatial Regionalization and Heterochrony in the Formation of Adult Pallial Neural Stem Cells Developmental Cell. Jul, 2014 | Pubmed ID: 25017692 Overnutrition Induces β-cell Differentiation Through Prolonged Activation of β-cells in Zebrafish Larvae American Journal of Physiology. Endocrinology and Metabolism. Apr, 2014 | Pubmed ID: 24473439 Conditional Gene-trap Mutagenesis in Zebrafish Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24233792 Efficient Multiplex Biallelic Zebrafish Genome Editing Using a CRISPR Nuclease System Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013 | Pubmed ID: 23918387 Targeted Overexpression of CKI-insensitive Cyclin-dependent Kinase 4 Increases Functional β-cell Number Through Enhanced Self-replication in Zebrafish Zebrafish. Jun, 2013 | Pubmed ID: 23544990 Conditional Control of Gene Function by an Invertible Gene Trap in Zebrafish Proceedings of the National Academy of Sciences of the United States of America. Sep, 2012 | Pubmed ID: 22908272 Nutrient Excess Stimulates β-cell Neogenesis in Zebrafish Diabetes. Oct, 2012 | Pubmed ID: 22721970 Generating Conditional Mutations in Zebrafish Using Gene-trap Mutagenesis Methods in Cell Biology. 2011 | Pubmed ID: 21924154 PhiC31 Integrase Induces Efficient Site-specific Excision in Zebrafish Transgenic Research. Feb, 2011 | Pubmed ID: 20556509 Pineal-specific Agouti Protein Regulates Teleost Background Adaptation Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20980662 Co-activation De Erizo Y Vías AKT Promover Tumorigenesis En Pez Cebra Molecular Cancer. 2009 | Pubmed ID: 19555497 FlEx-based Transgenic Reporter Lines for Visualization of Cre and Flp Activity in Live Zebrafish Genesis (New York, N.Y. : 2000). Jul, 2009 | Pubmed ID: 19415631 A Gain-of-function Screen in Zebrafish Identifies a Guanylate Cyclase with a Role in Neuronal Degeneration Molecular Genetics and Genomics : MGG. May, 2009 | Pubmed ID: 19221799 Microinyección de la proteína CRISPR/Cas9 en bagre de canal, Ictalurus punctatus, embriones de Gene Editing Ahmed Elaswad*1,2, Karim Khalil*1,3, David Cline1, Patrick Page-McCaw4, Wenbiao Chen4, Maximilian Michel5, Roger Cone5, Rex Dunham1 1School of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, 2Department of Animal Wealth Development, Faculty of Veterinary Medicine, Suez Canal University, 3Anatomy and Embryology Department, Faculty of Veterinary Medicine, Cairo University, 4Department of Molecular Physiology and Biophysics, Vanderbilt University, 5Life Science Institute, University of Michigan JoVE 56275 Genetics
Microinyección de la proteína CRISPR/Cas9 en bagre de canal, Ictalurus punctatus, embriones de Gene Editing Ahmed Elaswad*1,2, Karim Khalil*1,3, David Cline1, Patrick Page-McCaw4, Wenbiao Chen4, Maximilian Michel5, Roger Cone5, Rex Dunham1 1School of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, 2Department of Animal Wealth Development, Faculty of Veterinary Medicine, Suez Canal University, 3Anatomy and Embryology Department, Faculty of Veterinary Medicine, Cairo University, 4Department of Molecular Physiology and Biophysics, Vanderbilt University, 5Life Science Institute, University of Michigan JoVE 56275 Genetics