William L. Dewey

Publications

• Ethanol Reversal of Cellular Tolerance to Morphine in Rat Locus Coeruleus Neurons
  Molecular Pharmacology. Aug, 2013  |   Pubmed ID: 23716621
• Electrophysiological Characteristics of Enteric Neurons Isolated from the Immortomouse
  Digestive Diseases and Sciences. Jun, 2013  |   Pubmed ID: 23371009
• Design, Synthesis, and Biological Evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan Derivatives As Peripheral Selective μ Opioid Receptor Agents
  Journal of Medicinal Chemistry. Nov, 2012  |   Pubmed ID: 23116124
• Morphine Decreases Enteric Neuron Excitability Via Inhibition of Sodium Channels
  PloS One. 2012  |   Pubmed ID: 23028881
• Contribution of Acid Sphingomyelinase in the Periaqueductal Gray Region to Morphine-induced Analgesia in Mice
  Neuroreport. Sep, 2012  |   Pubmed ID: 22825003
• Evidence for the Putative Cannabinoid Receptor (GPR55)-mediated Inhibitory Effects on Intestinal Contractility in Mice
  Pharmacology. 2012  |   Pubmed ID: 22759743
• Production and Actions of the Anandamide Metabolite Prostamide E2 in the Renal Medulla
  The Journal of Pharmacology and Experimental Therapeutics. Sep, 2012  |   Pubmed ID: 22685343
• 6β-N-heterocyclic Substituted Naltrexamine Derivative NAP As a Potential Lead to Develop Peripheral Mu Opioid Receptor Selective Antagonists
  Bioorganic & Medicinal Chemistry Letters. Jul, 2012  |   Pubmed ID: 22683223
• Morphine Efficacy is Altered in Conditional HIV-1 Tat Transgenic Mice
  European Journal of Pharmacology. Aug, 2012  |   Pubmed ID: 22659585
• Differences in the Characteristics of Tolerance to μ-opioid Receptor Agonists in the Colon from Wild Type and β-arrestin2 Knockout Mice
  European Journal of Pharmacology. Jun, 2012  |   Pubmed ID: 22521552
• Opioid-induced Hypernociception is Associated with Hyperexcitability and Altered Tetrodotoxin-resistant Na+ Channel Function of Dorsal Root Ganglia
  American Journal of Physiology. Cell Physiology. Apr, 2012  |   Pubmed ID: 22189556
• The Role of β-arrestin2 in the Mechanism of Morphine Tolerance in the Mouse and Guinea Pig Gastrointestinal Tract
  The Journal of Pharmacology and Experimental Therapeutics. Mar, 2012  |   Pubmed ID: 22129596
• Characterization of 6α- and 6β-N-heterocyclic Substituted Naltrexamine Derivatives As Novel Leads to Development of Mu Opioid Receptor Selective Antagonists
  ACS Chemical Neuroscience. Jul, 2011  |   Pubmed ID: 22816021
• Chronic Neuropathic Pain in Mice Reduces μ-opioid Receptor-mediated G-protein Activity in the Thalamus
  Brain Research. Aug, 2011  |   Pubmed ID: 21762883
• μ-opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate Internalization
  Molecular Pharmacology. Oct, 2010  |   Pubmed ID: 20647394
• Role of CD38, a Cyclic ADP-ribosylcyclase, in Morphine Antinociception and Tolerance
  The Journal of Pharmacology and Experimental Therapeutics. Sep, 2010  |   Pubmed ID: 20551293
• Chronic Constriction Injury Reduces Cannabinoid Receptor 1 Activity in the Rostral Anterior Cingulate Cortex of Mice
  Brain Research. Jun, 2010  |   Pubmed ID: 20380816
• Design, Synthesis, and Biological Evaluation of 6alpha- and 6beta-N-heterocyclic Substituted Naltrexamine Derivatives As Mu Opioid Receptor Selective Antagonists
  Journal of Medicinal Chemistry. Mar, 2009  |   Pubmed ID: 19199782
• Formation and Function of Ceramide-enriched Membrane Platforms with CD38 During M1-receptor Stimulation in Bovine Coronary Arterial Myocytes
  American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2008  |   Pubmed ID: 18723763
• Morphine Tolerance in the Mouse Ileum and Colon
  The Journal of Pharmacology and Experimental Therapeutics. Nov, 2008  |   Pubmed ID: 18682567
• Pre-treatment with a PKC or PKA Inhibitor Prevents the Development of Morphine Tolerance but Not Physical Dependence in Mice
  Brain Research. Jun, 2008  |   Pubmed ID: 18501877
• Local Production of O2- by NAD(P)H Oxidase in the Sarcoplasmic Reticulum of Coronary Arterial Myocytes: CADPR-mediated Ca2+ Regulation
  Cellular Signalling. Apr, 2008  |   Pubmed ID: 18207366
• MGluR5 Antagonists That Block Calcium Mobilization in Vitro Also Reverse (S)-3,5-DHPG-induced Hyperalgesia and Morphine Antinociceptive Tolerance in Vivo
  Brain Research. Jan, 2008  |   Pubmed ID: 18022146
• Evidence for an Important Role of Protein Phosphatases in the Mechanism of Morphine Tolerance
  Brain Research. Jul, 2007  |   Pubmed ID: 17582387
• Synthesis and Pharmacological Evaluation of Phenylethynyl[1,2,4]methyltriazines As Analogues of 3-methyl-6-(phenylethynyl)pyridine
  Journal of Medicinal Chemistry. Jul, 2007  |   Pubmed ID: 17569516
• Decrease in N-methyl-D-aspartic Acid Receptor-NR2B Subunit Levels by Intrathecal Short-hairpin RNA Blocks Group I Metabotropic Glutamate Receptor-mediated Hyperalgesia
  The Journal of Pharmacology and Experimental Therapeutics. Jul, 2007  |   Pubmed ID: 17405869
• Determination of the Role of Conventional, Novel and Atypical PKC Isoforms in the Expression of Morphine Tolerance in Mice
  Pain. Jan, 2007  |   Pubmed ID: 16965856
• PKC and PKA Inhibitors Reinstate Morphine-induced Behaviors in Morphine Tolerant Mice
  Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Dec, 2006  |   Pubmed ID: 17056270
• How Important is Protein Kinase C in Mu-opioid Receptor Desensitization and Morphine Tolerance?
  Trends in Pharmacological Sciences. Nov, 2006  |   Pubmed ID: 17000011
• Pharmacological Characterization of Novel Water-soluble Cannabinoids
  The Journal of Pharmacology and Experimental Therapeutics. Sep, 2006  |   Pubmed ID: 16757541
• Protein Kinase Inhibitor Peptide (PKI): a Family of Endogenous Neuropeptides That Modulate Neuronal CAMP-dependent Protein Kinase Function
  Neuropeptides. Feb, 2006  |   Pubmed ID: 16442618
• Protein Kinase A Activity is Increased in Mouse Lumbar Spinal Cord but Not Brain Following Morphine Antinociceptive Tolerance for 15 Days
  Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Sep, 2005  |   Pubmed ID: 16026714
• Chronic Delta9-tetrahydrocannabinol Treatment Produces Antinociceptive Tolerance in Mice Without Altering Protein Kinase A Activity in Mouse Brain and Spinal Cord
  Biochemical Pharmacology. Jul, 2005  |   Pubmed ID: 15913565
• Alterations in Brain Protein Kinase A Activity and Reversal of Morphine Tolerance by Two Fragments of Native Protein Kinase A Inhibitor Peptide (PKI)
  Neuropharmacology. Apr, 2005  |   Pubmed ID: 15814100
• Task Specificity of Cross-tolerance Between Delta9-tetrahydrocannabinol and Anandamide Analogs in Mice
  European Journal of Pharmacology. Mar, 2005  |   Pubmed ID: 15740725
• PKC and PKA Inhibitors Reverse Tolerance to Morphine-induced Hypothermia and Supraspinal Analgesia in Mice
  European Journal of Pharmacology. May, 2004  |   Pubmed ID: 15178359
• Effects of MGlu1 and MGlu5 Metabotropic Glutamate Antagonists to Reverse Morphine Tolerance in Mice
  European Journal of Pharmacology. May, 2004  |   Pubmed ID: 15178357
• The Expression of a High Level of Morphine Antinociceptive Tolerance in Mice Involves Both PKC and PKA
  Brain Research. Sep, 2003  |   Pubmed ID: 12957370
• Prolonged Reversal of Morphine Tolerance with No Reversal of Dependence by Protein Kinase C Inhibitors
  Brain Research. Dec, 2002  |   Pubmed ID: 12468027