William M. Old

Publications

• Hidden Resources in the Genome Restore PLP Synthesis and Robust Growth After Deletion of the Essential Gene
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2019   |   Pubmed ID: 31712440
• Temporal Metabolite, Ion, and Enzyme Activity Profiling Using Fluorescence Microscopy and Genetically Encoded Biosensors
  Methods in Molecular Biology (Clifton, N.J.). Month, 2019   |   Pubmed ID: 31119673
• The Nuclear Interactome of DYRK1A Reveals a Functional Role in DNA Damage Repair
  Scientific Reports. Apr, 2019   |   Pubmed ID: 31024071
• A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission
  Cell. 09, 2018   |   Pubmed ID: 30220460
• Synonymous Mutations Make Dramatic Contributions to Fitness when Growth is Limited by a Weak-link Enzyme
  PLoS Genetics. 08, 2018   |   Pubmed ID: 30148850
• Dengue Viruses Cleave STING in Humans but Not in Nonhuman Primates, Their Presumed Natural Reservoir
  ELife. 03, 2018   |   Pubmed ID: 29557779
• Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells
  Molecular & Cellular Proteomics : MCP. 04, 2018   |   Pubmed ID: 29255136
• Identification of the Primary Peptide Contaminant That Inhibits Fibrillation and Toxicity in Synthetic Amyloid-β42
  PloS One. Month, 2017   |   Pubmed ID: 28792968
• Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications
  Cell Reports. 08, 2017   |   Pubmed ID: 28768201
• A Synonymous Mutation Upstream of the Gene Encoding a Weak-Link Enzyme Causes an Ultrasensitive Response in Growth Rate
  Journal of Bacteriology. 10, 2016   |   Pubmed ID: 27501982
• Identification of Mediator Kinase Substrates in Human Cells Using Cortistatin A and Quantitative Phosphoproteomics
  Cell Reports. Apr, 2016   |   Pubmed ID: 27050516
• Erratum To: Large-Scale Examination of Factors Influencing Phosphopeptide Neutral Loss During Collision Induced Dissociation
  Journal of the American Society for Mass Spectrometry. Oct, 2015   |   Pubmed ID: 26169511
• Centromere Protein F Includes Two Sites That Couple Efficiently to Depolymerizing Microtubules
  The Journal of Cell Biology. Jun, 2015   |   Pubmed ID: 26101217
• Large-Scale Examination of Factors Influencing Phosphopeptide Neutral Loss During Collision Induced Dissociation
  Journal of the American Society for Mass Spectrometry. Jul, 2015   |   Pubmed ID: 25851653
• A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells
  Molecular & Cellular Proteomics : MCP. Jun, 2015   |   Pubmed ID: 25850435
• Identification of a Family of Fatty-acid-speciated Sonic Hedgehog Proteins, Whose Members Display Differential Biological Properties
  Cell Reports. Mar, 2015   |   Pubmed ID: 25732819
• Gas-phase Acidities of Nitrated Azoles As Determined by the Extended Kinetic Method and Computations
  The Journal of Physical Chemistry. A. Jan, 2015   |   Pubmed ID: 25521708
• Development of Substrate-selective Probes for Affinity Pulldown of Histone Demethylases
  ACS Chemical Biology. Jan, 2015   |   Pubmed ID: 25335116
• Licensing of Yeast Centrosome Duplication Requires Phosphoregulation of Sfi1
  PLoS Genetics. Oct, 2014   |   Pubmed ID: 25340401
• Identification of Global Ferredoxin Interaction Networks in Chlamydomonas Reinhardtii
  The Journal of Biological Chemistry. Dec, 2013   |   Pubmed ID: 24100040
• The Non-coding B2 RNA Binds to the DNA Cleft and Active-site Region of RNA Polymerase II
  Journal of Molecular Biology. Oct, 2013   |   Pubmed ID: 23416138
• IsoformResolver: A Peptide-centric Algorithm for Protein Inference
  Journal of Proteome Research. Jul, 2011   |   Pubmed ID: 21599010
• Spectrum-to-spectrum Searching Using a Proteome-wide Spectral Library
  Molecular & Cellular Proteomics : MCP. Jul, 2011   |   Pubmed ID: 21532008
• Quantifying the Impact of Chimera MS/MS Spectra on Peptide Identification in Large-scale Proteomics Studies
  Journal of Proteome Research. Aug, 2010   |   Pubmed ID: 20578722
• Functional Proteomics Identifies Targets of Phosphorylation by B-Raf Signaling in Melanoma
  Molecular Cell. Apr, 2009   |   Pubmed ID: 19362540
• Budding Yeast Centrosome Duplication Requires Stabilization of Spc29 Via Mps1-mediated Phosphorylation
  The Journal of Biological Chemistry. May, 2009   |   Pubmed ID: 19269975
• A Simulated MS/MS Library for Spectrum-to-spectrum Searching in Large Scale Identification of Proteins
  Molecular & Cellular Proteomics : MCP. Apr, 2009   |   Pubmed ID: 19106086
• Mapping Protein Post-translational Modifications with Mass Spectrometry
  Nature Methods. Oct, 2007   |   Pubmed ID: 17901869
• Mps1 Activation Loop Autophosphorylation Enhances Kinase Activity
  The Journal of Biological Chemistry. Oct, 2007   |   Pubmed ID: 17728254
• Achieving In-depth Proteomics Profiling by Mass Spectrometry
  ACS Chemical Biology. Jan, 2007   |   Pubmed ID: 17243782
• Improved Validation of Peptide MS/MS Assignments Using Spectral Intensity Prediction
  Molecular & Cellular Proteomics : MCP. Jan, 2007   |   Pubmed ID: 17018520
• Comparison of Label-free Methods for Quantifying Human Proteins by Shotgun Proteomics
  Molecular & Cellular Proteomics : MCP. Oct, 2005   |   Pubmed ID: 15979981
• Improving Reproducibility and Sensitivity in Identifying Human Proteins by Shotgun Proteomics
  Analytical Chemistry. Jul, 2004   |   Pubmed ID: 15228325