William P. Schiemann

Publications

• Deconstructing the Mechanisms and Consequences of TGF-β-induced EMT During Cancer Progression
  Cell and Tissue Research. Jan, 2012  |   Pubmed ID: 21691718
• Role of TGF-β and the Tumor Microenvironment During Mammary Tumorigenesis
  Gene Expression. 2011  |   Pubmed ID: 22268294
• NetSlim: High-confidence Curated Signaling Maps
  Database : the Journal of Biological Databases and Curation. 2011  |   Pubmed ID: 21959865
• β3 Integrin-EGF Receptor Cross-talk Activates P190RhoGAP in Mouse Mammary Gland Epithelial Cells
  Molecular Biology of the Cell. Nov, 2011  |   Pubmed ID: 21937717
• Krüppel-like Factor 4 Inhibits Tumorigenic Progression and Metastasis in a Mouse Model of Breast Cancer
  Neoplasia (New York, N.Y.). Jul, 2011  |   Pubmed ID: 21750654
• Down-regulation of Epithelial Cadherin is Required to Initiate Metastatic Outgrowth of Breast Cancer
  Molecular Biology of the Cell. Jul, 2011  |   Pubmed ID: 21613543
• Lysyl Oxidase Contributes to Mechanotransduction-mediated Regulation of Transforming Growth Factor-β Signaling in Breast Cancer Cells
  Neoplasia (New York, N.Y.). May, 2011  |   Pubmed ID: 21532881
• Noncanonical TGF-β Signaling During Mammary Tumorigenesis
  Journal of Mammary Gland Biology and Neoplasia. Jun, 2011  |   Pubmed ID: 21448580
• Fibromodulin Suppresses Nuclear Factor-kappaB Activity by Inducing the Delayed Degradation of IKBA Via a JNK-dependent Pathway Coupled to Fibroblast Apoptosis
  The Journal of Biological Chemistry. Feb, 2011  |   Pubmed ID: 21156791
• The Cain and Abl of Epithelial-mesenchymal Transition and Transforming Growth Factor-β in Mammary Epithelial Cells
  Cells, Tissues, Organs. 2011  |   Pubmed ID: 21051857
• Transforming Growth Factor-β and the Hallmarks of Cancer
  Cellular Signalling. Jun, 2011  |   Pubmed ID: 20940046
• Colorectal Cancer in the Cotton Top Tamarin (Saguinus Oedipus): How Do They Evade Liver Metastasis?
  Digestive Diseases and Sciences. Feb, 2011  |   Pubmed ID: 20645001
• Homeoprotein Six1 Increases TGF-beta Type I Receptor and Converts TGF-beta Signaling from Suppressive to Supportive for Tumor Growth
  Cancer Research. Dec, 2010  |   Pubmed ID: 21056993
• The Pathophysiology of Epithelial-mesenchymal Transition Induced by Transforming Growth Factor-beta in Normal and Malignant Mammary Epithelial Cells
  Journal of Mammary Gland Biology and Neoplasia. Jun, 2010  |   Pubmed ID: 20467795
• Repo-man Controls a Protein Phosphatase 1-dependent Threshold for DNA Damage Checkpoint Activation
  Current Biology : CB. Mar, 2010  |   Pubmed ID: 20188555
• PGE2 Receptor EP2 Mediates the Antagonistic Effect of COX-2 on TGF-beta Signaling During Mammary Tumorigenesis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2010  |   Pubmed ID: 19897661
• Mechanisms of the Epithelial-mesenchymal Transition by TGF-beta
  Future Oncology (London, England). Oct, 2009  |   Pubmed ID: 19852727
• Epithelial-mesenchymal Transition in Tumor Metastasis: a Method to the Madness
  Future Oncology (London, England). Oct, 2009  |   Pubmed ID: 19852724
• P130Cas is Required for Mammary Tumor Growth and Transforming Growth Factor-beta-mediated Metastasis Through Regulation of Smad2/3 Activity
  The Journal of Biological Chemistry. Dec, 2009  |   Pubmed ID: 19822523
• Therapeutic Targeting of the Focal Adhesion Complex Prevents Oncogenic TGF-beta Signaling and Metastasis
  Breast Cancer Research : BCR. 2009  |   Pubmed ID: 19740433
• The Six1 Homeoprotein Induces Human Mammary Carcinoma Cells to Undergo Epithelial-mesenchymal Transition and Metastasis in Mice Through Increasing TGF-beta Signaling
  The Journal of Clinical Investigation. Sep, 2009  |   Pubmed ID: 19726885
• Preclinical Efficacy of Cystatin C to Target the Oncogenic Activity of Transforming Growth Factor Beta in Breast Cancer
  Translational Oncology. Aug, 2009  |   Pubmed ID: 19701502
• Activated Abl Kinase Inhibits Oncogenic Transforming Growth Factor-beta Signaling and Tumorigenesis in Mammary Tumors
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2009  |   Pubmed ID: 19690215
• X-linked Inhibitor of Apoptosis Protein and Its E3 Ligase Activity Promote Transforming Growth Factor-{beta}-mediated Nuclear Factor-{kappa}B Activation During Breast Cancer Progression
  The Journal of Biological Chemistry. Aug, 2009  |   Pubmed ID: 19531477
• The TGF-beta Paradox in Human Cancer: an Update
  Future Oncology (London, England). Mar, 2009  |   Pubmed ID: 19284383
• Cox-2 Inactivates Smad Signaling and Enhances EMT Stimulated by TGF-beta Through a PGE2-dependent Mechanisms
  Carcinogenesis. Nov, 2008  |   Pubmed ID: 18725385
• Transcriptional and Translational Regulation of TGF-beta Production in Response to Apoptotic Cells
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2008  |   Pubmed ID: 18714031
• Fibulin-5 Initiates Epithelial-mesenchymal Transition (EMT) and Enhances EMT Induced by TGF-beta in Mammary Epithelial Cells Via a MMP-dependent Mechanism
  Carcinogenesis. Dec, 2008  |   Pubmed ID: 18713838
• Microfibril-associate Glycoprotein-2 (MAGP-2) Promotes Angiogenic Cell Sprouting by Blocking Notch Signaling in Endothelial Cells
  Microvascular Research. May, 2008  |   Pubmed ID: 18417156
• Altered TAB1:I KappaB Kinase Interaction Promotes Transforming Growth Factor Beta-mediated Nuclear Factor-kappaB Activation During Breast Cancer Progression
  Cancer Research. Mar, 2008  |   Pubmed ID: 18316610
• Grb2 Binding to Tyr284 in TbetaR-II is Essential for Mammary Tumor Growth and Metastasis Stimulated by TGF-beta
  Carcinogenesis. Feb, 2008  |   Pubmed ID: 18174260
• Transcriptome Analysis of Endothelial Cell Gene Expression Induced by Growth on Matrigel Matrices: Identification and Characterization of MAGP-2 and Lumican As Novel Regulators of Angiogenesis
  Angiogenesis. 2007  |   Pubmed ID: 17632767
• Targeted TGF-beta Chemotherapies: Friend or Foe in Treating Human Malignancies?
  Expert Review of Anticancer Therapy. May, 2007  |   Pubmed ID: 17492924
• Src Phosphorylates Tyr284 in TGF-beta Type II Receptor and Regulates TGF-beta Stimulation of P38 MAPK During Breast Cancer Cell Proliferation and Invasion
  Cancer Research. Apr, 2007  |   Pubmed ID: 17440088
• Role of Transforming Growth Factor-beta in Cancer Progression
  Future Oncology (London, England). Dec, 2006  |   Pubmed ID: 17155901
• Apoptotic Cells, Through Transforming Growth Factor-beta, Coordinately Induce Anti-inflammatory and Suppress Pro-inflammatory Eicosanoid and NO Synthesis in Murine Macrophages
  The Journal of Biological Chemistry. Dec, 2006  |   Pubmed ID: 17056601
• Beta3 Integrin and Src Facilitate Transforming Growth Factor-beta Mediated Induction of Epithelial-mesenchymal Transition in Mammary Epithelial Cells
  Breast Cancer Research : BCR. 2006  |   Pubmed ID: 16859511
• TGF-beta in Cancer and Other Diseases
  Future Oncology (London, England). Apr, 2006  |   Pubmed ID: 16563087
• Fibulins 3 and 5 Antagonize Tumor Angiogenesis in Vivo
  Cancer Research. Mar, 2006  |   Pubmed ID: 16510581
• Fibulin-5 Function During Tumorigenesis
  Future Oncology (London, England). Feb, 2005  |   Pubmed ID: 16555973
• The Use of Cystatin C to Inhibit Epithelial-mesenchymal Transition and Morphological Transformation Stimulated by Transforming Growth Factor-beta
  Breast Cancer Research : BCR. 2005  |   Pubmed ID: 16168131
• Identification and Characterization of Regulator of G Protein Signaling 4 (RGS4) As a Novel Inhibitor of Tubulogenesis: RGS4 Inhibits Mitogen-activated Protein Kinases and Vascular Endothelial Growth Factor Signaling
  Molecular Biology of the Cell. Feb, 2005  |   Pubmed ID: 15548600
• Fibulin-2 and Fibulin-5 Alterations in Tsk Mice Associated with Disorganized Hypodermal Elastic Fibers and Skin Tethering
  The Journal of Investigative Dermatology. Dec, 2004  |   Pubmed ID: 15610515
• Fibulin-5 Promotes Wound Healing in Vivo
  Journal of the American College of Surgeons. Sep, 2004  |   Pubmed ID: 15325610
• Fibulin-5 Antagonizes Vascular Endothelial Growth Factor (VEGF) Signaling and Angiogenic Sprouting by Endothelial Cells
  DNA and Cell Biology. Jun, 2004  |   Pubmed ID: 15231070
• Pigment Epithelium-derived Factor in Idiopathic Pulmonary Fibrosis: a Role in Aberrant Angiogenesis
  American Journal of Respiratory and Critical Care Medicine. Aug, 2004  |   Pubmed ID: 15117744
• Transforming Growth Factor-beta (TGF-beta)-resistant B Cells from Chronic Lymphocytic Leukemia Patients Contain Recurrent Mutations in the Signal Sequence of the Type I TGF-beta Receptor
  Cancer Detection and Prevention. 2004  |   Pubmed ID: 15041079
• Cystatin C Antagonizes Transforming Growth Factor Beta Signaling in Normal and Cancer Cells
  Molecular Cancer Research : MCR. Mar, 2004  |   Pubmed ID: 15037657
• Cloning of a Novel Signaling Molecule, AMSH-2, That Potentiates Transforming Growth Factor Beta Signaling
  BMC Cell Biology. Jan, 2004  |   Pubmed ID: 14728725
• Development of Human Protein Reference Database As an Initial Platform for Approaching Systems Biology in Humans
  Genome Research. Oct, 2003  |   Pubmed ID: 14525934
• SPARC Inhibits Epithelial Cell Proliferation in Part Through Stimulation of the Transforming Growth Factor-beta-signaling System
  Molecular Biology of the Cell. Oct, 2003  |   Pubmed ID: 14517312
• Context-specific Effects of Fibulin-5 (DANCE/EVEC) on Cell Proliferation, Motility, and Invasion. Fibulin-5 is Induced by Transforming Growth Factor-beta and Affects Protein Kinase Cascades
  The Journal of Biological Chemistry. Jul, 2002  |   Pubmed ID: 12021267
• Cross-talk Between ERK and P38 MAPK Mediates Selective Suppression of Pro-inflammatory Cytokines by Transforming Growth Factor-beta
  The Journal of Biological Chemistry. Apr, 2002  |   Pubmed ID: 11842088