Wolfhard Semmler Department of Medical Physics in Radiology German Cancer Research Center, Heidelberg, Germany Biography Publications Institution JoVE Articles Wolfhard Semmler has not added a biography. If you are Wolfhard Semmler and would like to personalize this page please email our Author Liaison for assistance. Publications BioShuttle Mobility in Living Cells Studied with High-Resolution FCS & CLSM Methodologies International Journal of Medical Sciences. 2012 | Pubmed ID: 22811608 A Cross-over Study of Effects on the Hypothalamus-pituitary-adrenal (HPA) Axis and the Sympathoadrenergic System in Magnetic Field Strength Exposure from 0 to 7 T Stress (Amsterdam, Netherlands). Aug, 2012 | Pubmed ID: 22775799 Quantitative Contrast-enhanced Ultrasound for Imaging Antiangiogenic Treatment Response in Experimental Osteolytic Breast Cancer Bone Metastases Investigative Radiology. Jul, 2012 | Pubmed ID: 22659593 Two Eyes See More Than One: Double Echo Stereoscopic MRA for Rapid 3D Visualization of Vascular Structures Magma (New York, N.Y.). Apr, 2012 | Pubmed ID: 22476546 Lung Ventilation- and Perfusion-weighted Fourier Decomposition Magnetic Resonance Imaging: In Vivo Validation with Hyperpolarized (3) He and Dynamic Contrast-enhanced MRI Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Mar, 2012 | Pubmed ID: 22392633 Synthesis and in Vitro Evaluation of 68Ga-DOTA-4-FBn-TN14003, a Novel Tracer for the Imaging of CXCR4 Expression Bioorganic & Medicinal Chemistry. Feb, 2012 | Pubmed ID: 22264762 Monitoring Molecular, Functional and Morphologic Aspects of Bone Metastases Using Non-invasive Imaging Current Pharmaceutical Biotechnology. Mar, 2012 | Pubmed ID: 22214500 Advanced Fit of the Diffusion Kurtosis Tensor by Directional Weighting and Regularization Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. May, 2012 | Pubmed ID: 22189630 Coaxial Waveguide MRI Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Apr, 2012 | Pubmed ID: 22021117 Velocity Navigator for Motion Compensated Thermometry Magma (New York, N.Y.). Feb, 2012 | Pubmed ID: 21373916 Theranostic CRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy Theranostics. 2011 | Pubmed ID: 22211144 A Novel PET Tracer for the Imaging of αvβ3 and αvβ5 Integrins in Experimental Breast Cancer Bone Metastases Contrast Media & Molecular Imaging. Nov-Dec, 2011 | Pubmed ID: 22162137 Determination of the Defining Boundary in Nuclear Magnetic Resonance Diffusion Experiments Physical Review Letters. Jul, 2011 | Pubmed ID: 21867047 MR Safety: Simultaneous B0, DΦ/dt, and DB/dt Measurements on MR-workers Up to 7 T Magma (New York, N.Y.). Dec, 2011 | Pubmed ID: 21755466 Effects of Static Magnetic Fields on Cognition, Vital Signs, and Sensory Perception: a Meta-analysis Journal of Magnetic Resonance Imaging : JMRI. Oct, 2011 | Pubmed ID: 21751291 3 Tesla Sodium Inversion Recovery Magnetic Resonance Imaging Allows for Improved Visualization of Intracellular Sodium Content Changes in Muscular Channelopathies Investigative Radiology. Dec, 2011 | Pubmed ID: 21750464 Cilengitide Inhibits Metastatic Bone Colonization in a Nude Rat Model Oncology Reports. Oct, 2011 | Pubmed ID: 21725616 The Potential of Relaxation-weighted Sodium Magnetic Resonance Imaging As Demonstrated on Brain Tumors Investigative Radiology. Sep, 2011 | Pubmed ID: 21577129 Outer Volume Suppression in Steady State Sequences (OVSuSS) for Percutaneous Interventions Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2011 | Pubmed ID: 21337422 Optically Detunable, Inductively Coupled Coil for Self-gating in Small Animal Magnetic Resonance Imaging Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Mar, 2011 | Pubmed ID: 21337415 First Multimodal Embolization Particles Visible on X-ray/computed Tomography and Magnetic Resonance Imaging Investigative Radiology. Mar, 2011 | Pubmed ID: 21263332 Compatibility Between 3T 1H SV-MRS Data and Automatic Brain Tumour Diagnosis Support Systems Based on Databases of 1.5T 1H SV-MRS Spectra Magma (New York, N.Y.). Feb, 2011 | Pubmed ID: 21249420 Sorafenib Tosylate and Paclitaxel Induce Anti-angiogenic, Anti-tumour and Anti-resorptive Effects in Experimental Breast Cancer Bone Metastases European Journal of Cancer (Oxford, England : 1990). Jan, 2011 | Pubmed ID: 20863686 Novel Spherical Phantoms for Q-ball Imaging Under in Vivo Conditions Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jan, 2011 | Pubmed ID: 20740652 Cilengitide Inhibits Progression of Experimental Breast Cancer Bone Metastases As Imaged Noninvasively Using VCT, MRI and DCE-MRI in a Longitudinal in Vivo Study International Journal of Cancer. Journal International Du Cancer. May, 2011 | Pubmed ID: 20648558 Improved Visualization of Delayed Perfusion in Lung MRI European Journal of Radiology. Jan, 2011 | Pubmed ID: 19713064 [Quantitative MR-Spectroscopy: Implementation and Quality Assurance on a Clinical MR-scanner] Zeitschrift Für Medizinische Physik. 2010 | Pubmed ID: 20663651 Active Microcoil Tracking in the Lungs Using a Semisolid Rubber As Signal Source Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2010 | Pubmed ID: 20572154 Drug-induced Vessel Remodeling in Bone Metastases As Assessed by Dynamic Contrast Enhanced Magnetic Resonance Imaging and Vessel Size Imaging: a Longitudinal in Vivo Study Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2010 | Pubmed ID: 20530698 A Long Arm for Ultrasound: a Combined Robotic Focused Ultrasound Setup for Magnetic Resonance-guided Focused Ultrasound Surgery Medical Physics. May, 2010 | Pubmed ID: 20527572 Anti-CD4-targeted Gold Nanoparticles Induce Specific Contrast Enhancement of Peripheral Lymph Nodes in X-ray Computed Tomography of Live Mice Nano Letters. Jul, 2010 | Pubmed ID: 20496900 Real-time MR Navigation and Localization of an Intravascular Catheter with Ferromagnetic Components Magma (New York, N.Y.). Jun, 2010 | Pubmed ID: 20495846 MMP Inhibition Blocks Fibroblast-dependent Skin Cancer Invasion, Reduces Vascularization and Alters VEGF-A and PDGF-BB Expression Anticancer Research. Mar, 2010 | Pubmed ID: 20392987 Comparison of Conventional Time-intensity Curves Vs. Maximum Intensity over Time for Post-processing of Dynamic Contrast-enhanced Ultrasound European Journal of Radiology. Jul, 2010 | Pubmed ID: 19945241 An Expandable Catheter Loop Coil for Intravascular MRI in Larger Blood Vessels Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Feb, 2010 | Pubmed ID: 19918897 Simulation-based Comparison of Two Approaches Frequently Used for Dynamic Contrast-enhanced MRI European Radiology. Feb, 2010 | Pubmed ID: 19727758 Gating in Small-animal Cardio-thoracic CT Methods (San Diego, Calif.). Jan, 2010 | Pubmed ID: 19651213 Sodium MRI Using a Density-adapted 3D Radial Acquisition Technique Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2009 | Pubmed ID: 19859915 Measurement of R1 Dynamics Using Sliding Window-DESPOT Journal of Magnetic Resonance Imaging : JMRI. Nov, 2009 | Pubmed ID: 19856450 RGD-labeled USPIO Inhibits Adhesion and Endocytotic Activity of Alpha V Beta3-integrin-expressing Glioma Cells and Only Accumulates in the Vascular Tumor Compartment Radiology. Nov, 2009 | Pubmed ID: 19789239 Molecular Ultrasound Imaging of Early Vascular Response in Prostate Tumors Irradiated with Carbon Ions Neoplasia (New York, N.Y.). Sep, 2009 | Pubmed ID: 19724679 Suppression of Pulmonary Vasculature in Lung Perfusion MRI Using Correlation Analysis European Radiology. Nov, 2009 | Pubmed ID: 19471936 Imaging Response to Systemic Therapy for Bone Metastases European Radiology. Oct, 2009 | Pubmed ID: 19468736 Assessment of Vascular Remodeling Under Antiangiogenic Therapy Using DCE-MRI and Vessel Size Imaging Journal of Magnetic Resonance Imaging : JMRI. May, 2009 | Pubmed ID: 19388117 Image Formation with a Microlens-based Optical Detector: a Three-dimensional Mapping Approach Applied Optics. Apr, 2009 | Pubmed ID: 19340119 Intrinsic Gating for Small-animal Computed Tomography: a Robust ECG-less Paradigm for Deriving Cardiac Phase Information and Functional Imaging Circulation. Cardiovascular Imaging. Nov, 2008 | Pubmed ID: 19808548 Molecular Imaging II. Preface Handbook of Experimental Pharmacology. 2008 | Pubmed ID: 18788125 Molecular Imaging I. Preface Handbook of Experimental Pharmacology. 2008 | Pubmed ID: 18763375 Vessel Fractions in Tumor Xenografts Depicted by Flow- or Contrast-sensitive Three-dimensional High-frequency Doppler Ultrasound Respond Differently to Antiangiogenic Treatment Cancer Research. Sep, 2008 | Pubmed ID: 18757418 Flow-compensated Self-gating Magma (New York, N.Y.). Sep, 2008 | Pubmed ID: 18668271 Fundamentals of Optical Imaging Handbook of Experimental Pharmacology. 2008 | Pubmed ID: 18626796 In Vivo Gd-DTPA Concentration for MR Lung Perfusion Measurements: Assessment with Computed Tomography in a Porcine Model European Radiology. Oct, 2008 | Pubmed ID: 18446343 Intrinsic Respiratory Gating in Small-animal CT European Radiology. Jul, 2008 | Pubmed ID: 18431578 Automatic Passive Tracking of an Endorectal Prostate Biopsy Device Using Phase-only Cross-correlation Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. May, 2008 | Pubmed ID: 18429016 Pharmacodynamics of Streptavidin-coated Cyanoacrylate Microbubbles Designed for Molecular Ultrasound Imaging Investigative Radiology. Mar, 2008 | Pubmed ID: 18301312 Molecular Profiling of Angiogenesis with Targeted Ultrasound Imaging: Early Assessment of Antiangiogenic Therapy Effects Molecular Cancer Therapeutics. Jan, 2008 | Pubmed ID: 18202013 Volumetric High-frequency Doppler Ultrasound Enables the Assessment of Early Antiangiogenic Therapy Effects on Tumor Xenografts in Nude Mice European Radiology. Apr, 2008 | Pubmed ID: 18084768 Retrospective Motion Gating in Small Animal CT of Mice and Rats Investigative Radiology. Oct, 2007 | Pubmed ID: 17984768 [An Algorithm for Passive Marker Localization in Interventional MRI] Zeitschrift Für Medizinische Physik. 2007 | Pubmed ID: 17879815 Impact of Stroma on the Growth, Microcirculation, and Metabolism of Experimental Prostate Tumors Neoplasia (New York, N.Y.). Jan, 2007 | Pubmed ID: 17325744 Specific Targeting of Tumor Angiogenesis by RGD-conjugated Ultrasmall Superparamagnetic Iron Oxide Particles Using a Clinical 1.5-T Magnetic Resonance Scanner Cancer Research. Feb, 2007 | Pubmed ID: 17308094 Silica- and Alkoxysilane-coated Ultrasmall Superparamagnetic Iron Oxide Particles: a Promising Tool to Label Cells for Magnetic Resonance Imaging Langmuir : the ACS Journal of Surfaces and Colloids. Jan, 2007 | Pubmed ID: 17241069 B1 Field-insensitive Transformers for RF-safe Transmission Lines Magma (New York, N.Y.). Nov, 2006 | Pubmed ID: 17115123 Dual-bolus Approach to Quantitative Measurement of Pulmonary Perfusion by Contrast-enhanced MRI Journal of Magnetic Resonance Imaging : JMRI. Dec, 2006 | Pubmed ID: 17051533 Dynamic Coil Selection for Real-time Imaging in Interventional MRI Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Nov, 2006 | Pubmed ID: 17029224 From 2D PET to 3D PET: Issues of Data Representation and Image Reconstruction Zeitschrift Für Medizinische Physik. 2006 | Pubmed ID: 16696369 Active Catheter Tracking Using Parallel MRI and Real-time Image Reconstruction Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jun, 2006 | Pubmed ID: 16683261 Comparison of Noncontact and Fiber-based Fluorescence-mediated Tomography Optics Letters. Mar, 2006 | Pubmed ID: 16544618 Synthesis and Characterization of HE-24.8: a Polymeric Contrast Agent for Magnetic Resonance Angiography Bioconjugate Chemistry. Jan-Feb, 2006 | Pubmed ID: 16417250 Potential Applications of Flat-panel Volumetric CT in Morphologic and Functional Small Animal Imaging Neoplasia (New York, N.Y.). Aug, 2005 | Pubmed ID: 16207475 Optical Molecular Imaging of Lymph Nodes Using a Targeted Vascular Contrast Agent Journal of Biomedical Optics. Jul-Aug, 2005 | Pubmed ID: 16178629 [Principles of Optical and Fluorescence Mediated Tomography in Turbid Media] Zeitschrift Für Medizinische Physik. 2005 | Pubmed ID: 16171039 [Status and Perspectives of Non Invasive Cell Tracking] Zeitschrift Für Medizinische Physik. 2005 | Pubmed ID: 16171038 Quantification of Aortic Elasticity: Development and Experimental Validation of a Method Using Computed Tomography European Radiology. Dec, 2005 | Pubmed ID: 16044295 Physical and Biological Characterization of Superparamagnetic Iron Oxide- and Ultrasmall Superparamagnetic Iron Oxide-labeled Cells: a Comparison Investigative Radiology. Aug, 2005 | Pubmed ID: 16024988 Influence of Different Breathing Maneuvers on Internal and External Organ Motion: Use of Fiducial Markers in Dynamic MRI International Journal of Radiation Oncology, Biology, Physics. May, 2005 | Pubmed ID: 15850927 [Measurements of Respiratory Motion Using Fast Magnetic Resonance Imaging and Inductively-coupled Marker Coils] Zeitschrift Für Medizinische Physik. 2005 | Pubmed ID: 15830783 Improved Correlation of Histological Data with DCE MRI Parameter Maps by 3D Reconstruction, Reslicing and Parameterization of the Histological Images European Radiology. Jun, 2005 | Pubmed ID: 15747142 Volumetric Computed Tomography (VCT): a New Technology for Noninvasive, High-resolution Monitoring of Tumor Angiogenesis Nature Medicine. Oct, 2004 | Pubmed ID: 15361864 Semiquantitative Fast Flow Velocity Measurements Using Catheter Coils with a Limited Sensitivity Profile Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Sep, 2004 | Pubmed ID: 15334577 [The Nobel Prize in "Physiology or Medicine" 2003 for the Discoveries Concerning Magnetic Resonance Imaging] Zeitschrift Für Medizinische Physik. 2004 | Pubmed ID: 15323285 Experimental Study of the Rat for the Assessment of Barium Coating on the Gastric Mucosa: Efficacy of Ranitidine and Acetylcysteine Administration Radiation Medicine. May-Jun, 2004 | Pubmed ID: 15287533 MR Coil Design for Simultaneous Tip Tracking and Curvature Delineation of a Catheter Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2004 | Pubmed ID: 15236390 Simple Models Improve the Discrimination of Prostate Cancers from the Peripheral Gland by T1-weighted Dynamic MRI European Radiology. Oct, 2004 | Pubmed ID: 15232714 Dynamic Contrast-enhanced Magnetic Resonance Imaging Rapidly Indicates Vessel Regression in Human Squamous Cell Carcinomas Grown in Nude Mice Caused by VEGF Receptor 2 Blockade with DC101 Neoplasia (New York, N.Y.). May-Jun, 2004 | Pubmed ID: 15153333 MR-guided Intravascular Procedures: Real-time Parameter Control and Automated Slice Positioning with Active Tracking Coils Journal of Magnetic Resonance Imaging : JMRI. May, 2004 | Pubmed ID: 15112307 [Automatic Slice Tracking in Interventional Magnetic Resonance Imaging] Zeitschrift Für Medizinische Physik. 2003 | Pubmed ID: 14562540 USPIO-enhanced Direct Thrombus MRI Academic Radiology. Aug, 2002 | Pubmed ID: 12188268 Targeting of Endothelin Receptors for Molecular Imaging of Atherosclerosis in Rabbits Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Mar, 2002 | Pubmed ID: 11884501 Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound Tobias Bäuerle1, Dorde Komljenovic1, Martin R. Berger2, Wolfhard Semmler1 1Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany, 2Unit of Chemotherapy and Toxicology, German Cancer Research Center, Heidelberg, Germany JoVE 4178 Medicine
Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound Tobias Bäuerle1, Dorde Komljenovic1, Martin R. Berger2, Wolfhard Semmler1 1Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany, 2Unit of Chemotherapy and Toxicology, German Cancer Research Center, Heidelberg, Germany JoVE 4178 Medicine
