Dr. Xue’s lab is focused on studying molecular mechanisms for inflammatory bowel disease (IBD) and colorectal cancer (CRC). He utilizes cell line and enteroid cultures, mouse models, patient tissues and a wide array of molecular and biochemical methodologies. Several ongoing projects in the lab include:
Why are micronutrients essential for cancer cell growth?
How does mitochondrial metabolism regulate the progress of cancer?
Whether stress activated pathways play a role in cancer cell metabolism?
What role does hypoxia signaling have in intestinal inflammation and colorectal cancer?
What is the critical link between nutrient homeostasis, inflammation and cancer?