Xiangru Lu

Publications

• North American Ginseng Inhibits Myocardial NOX2-ERK1/2 Signaling and Tumor Necrosis Factor-α Expression in Endotoxemia
  Pharmacological Research. Jun, 2016  |   Pubmed ID: 27317946
• Inhibition of Rac1 Reduces Store Overload-induced Calcium Release and Protects Against Ventricular Arrhythmia
  Journal of Cellular and Molecular Medicine. May, 2016  |   Pubmed ID: 27222313
• Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development
  Journal of the American Heart Association. Jan, 2016  |   Pubmed ID: 26722124
• Pregestational Diabetes Induces Fetal Coronary Artery Malformation Via Reactive Oxygen Species Signaling
  Diabetes. Apr, 2015  |   Pubmed ID: 25422104
• Rac1 Signaling is Critical to Cardiomyocyte Polarity and Embryonic Heart Development
  Journal of the American Heart Association. Oct, 2014  |   Pubmed ID: 25315346
• Cardiac-specific Overexpression of Human Stem Cell Factor Promotes Epicardial Activation and Arteriogenesis After Myocardial Infarction
  Circulation. Heart Failure. Sep, 2014  |   Pubmed ID: 25107671
• N-Acetylcysteine Prevents Congenital Heart Defects Induced by Pregestational Diabetes
  Cardiovascular Diabetology. 2014  |   Pubmed ID: 24533448
• Recombinant Human Annexin A5 Inhibits Proinflammatory Response and Improves Cardiac Function and Survival in Mice with Endotoxemia
  Critical Care Medicine. Jan, 2014  |   Pubmed ID: 24145837
• Nitric Oxide Synthase-3 Deficiency Results in Hypoplastic Coronary Arteries and Postnatal Myocardial Infarction
  European Heart Journal. Apr, 2014  |   Pubmed ID: 23048191
• Nitric Oxide Synthase-3 Promotes Embryonic Development of Atrioventricular Valves
  PloS One. 2013  |   Pubmed ID: 24204893
• Cardiomyocyte-specific Overexpression of Human Stem Cell Factor Protects Against Myocardial Ischemia and Reperfusion Injury
  International Journal of Cardiology. Oct, 2013  |   Pubmed ID: 23680593
• Inhibition of Na/K-ATPase Promotes Myocardial Tumor Necrosis Factor-alpha Protein Expression and Cardiac Dysfunction Via Calcium/mTOR Signaling in Endotoxemia
  Basic Research in Cardiology. Mar, 2012  |   Pubmed ID: 22351078
• Mitogen-activated Protein Kinase Phosphatase-1 Inhibits Myocardial TNF-α Expression and Improves Cardiac Function During Endotoxemia
  Cardiovascular Research. Mar, 2012  |   Pubmed ID: 22198506
• Transfusion of Fresh but Not Old Stored Blood Reduces Infarct Size and Improves Cardiac Function After Acute Myocardial Infarction in Anemic Rats*
  Critical Care Medicine. Mar, 2012  |   Pubmed ID: 22001589
• North American Ginseng Protects the Heart from Ischemia and Reperfusion Injury Via Upregulation of Endothelial Nitric Oxide Synthase
  Pharmacological Research. Sep, 2011  |   Pubmed ID: 21621617
• Deficiency in TIMP-3 Increases Cardiac Rupture and Mortality Post-myocardial Infarction Via EGFR Signaling: Beneficial Effects of Cetuximab
  Basic Research in Cardiology. May, 2011  |   Pubmed ID: 21243368
• Rac1 Activation Induces Tumour Necrosis Factor-α Expression and Cardiac Dysfunction in Endotoxemia
  Journal of Cellular and Molecular Medicine. May, 2011  |   Pubmed ID: 20518848
• Erythropoietin is Equally Effective As Fresh-blood Transfusion at Reducing Infarct Size in Anemic Rats
  Critical Care Medicine. Nov, 2010  |   Pubmed ID: 20693887
• NOX2 Deficiency Protects Against Streptozotocin-induced Beta-cell Destruction and Development of Diabetes in Mice
  Diabetes. Oct, 2010  |   Pubmed ID: 20627937
• Comparison of Initial Cell Retention and Clearance Kinetics After Subendocardial or Subepicardial Injections of Endothelial Progenitor Cells in a Canine Myocardial Infarction Model
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Mar, 2010  |   Pubmed ID: 20150266
• Effects of Anemia and Blood Transfusion in Acute Myocardial Infarction in Rats
  Transfusion. Jan, 2010  |   Pubmed ID: 19778337
• Neuronal Nitric Oxide Synthase Protects Against Myocardial Infarction-induced Ventricular Arrhythmia and Mortality in Mice
  Circulation. Oct, 2009  |   Pubmed ID: 19770398
• Cardiomyocyte-specific Overexpression of Human Stem Cell Factor Improves Cardiac Function and Survival After Myocardial Infarction in Mice
  Circulation. Sep, 2009  |   Pubmed ID: 19738140
• Endothelial Nitric Oxide Synthase Promotes Bone Marrow Stromal Cell Migration to the Ischemic Myocardium Via Upregulation of Stromal Cell-derived Factor-1alpha
  Stem Cells (Dayton, Ohio). Apr, 2009  |   Pubmed ID: 19353524
• Tissue Inhibitor of Metalloproteinase-3 Inhibits Neonatal Mouse Cardiomyocyte Proliferation Via EGFR/JNK/SP-1 Signaling
  American Journal of Physiology. Cell Physiology. Apr, 2009  |   Pubmed ID: 19211917
• JNK1/c-fos Inhibits Cardiomyocyte TNF-alpha Expression Via a Negative Crosstalk with ERK and P38 MAPK in Endotoxaemia
  Cardiovascular Research. Mar, 2009  |   Pubmed ID: 19043087
• Role of Heme Oxygenase-1 in the Cardioprotective Effects of Erythropoietin During Myocardial Ischemia and Reperfusion
  American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2009  |   Pubmed ID: 18996987
• Longitudinal Follow-up of Cardiac Structure and Functional Changes in an Infarct Mouse Model Using Retrospectively Gated Micro-computed Tomography
  Investigative Radiology. Jul, 2008  |   Pubmed ID: 18580335
• Endothelial Nitric Oxide Synthase Promotes Neonatal Cardiomyocyte Proliferation by Inhibiting Tissue Inhibitor of Metalloproteinase-3 Expression
  Cardiovascular Research. Jul, 2007  |   Pubmed ID: 17553475
• Role of Neuronal Nitric Oxide Synthase in Lipopolysaccharide-induced Tumor Necrosis Factor-alpha Expression in Neonatal Mouse Cardiomyocytes
  Cardiovascular Research. Jul, 2007  |   Pubmed ID: 17466955
• Erythropoietin Protects Cardiomyocytes from Apoptosis Via Up-regulation of Endothelial Nitric Oxide Synthase
  Cardiovascular Research. Oct, 2006  |   Pubmed ID: 16904088
• Lack of Endothelial Nitric Oxide Synthase Decreases Cardiomyocyte Proliferation and Delays Cardiac Maturation
  American Journal of Physiology. Cell Physiology. Dec, 2006  |   Pubmed ID: 16822949
• Role of Tumor Necrosis Factor-alpha in Myocardial Dysfunction and Apoptosis During Hindlimb Ischemia and Reperfusion
  Critical Care Medicine. Feb, 2006  |   Pubmed ID: 16424732
• Fasudil, a Rho-kinase Inhibitor, Attenuates Angiotensin II-induced Abdominal Aortic Aneurysm in Apolipoprotein E-deficient Mice by Inhibiting Apoptosis and Proteolysis
  Circulation. May, 2005  |   Pubmed ID: 15851596
• Pivotal Role of Gp91phox-containing NADH Oxidase in Lipopolysaccharide-induced Tumor Necrosis Factor-alpha Expression and Myocardial Depression
  Circulation. Apr, 2005  |   Pubmed ID: 15795323
• NADH Oxidase Signaling Induces Cyclooxygenase-2 Expression During Lipopolysaccharide Stimulation in Cardiomyocytes
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2005  |   Pubmed ID: 15546960
• Endogenous Heme Oxygenase Induction is a Critical Mechanism Attenuating Apoptosis and Restoring Microvascular Perfusion Following Limb Ischemia/reperfusion
  Surgery. Jul, 2004  |   Pubmed ID: 15232541
• In Vivo TNF-alpha Inhibition Ameliorates Cardiac Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Experimental Heart Failure
  American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2004  |   Pubmed ID: 15205165
• Upregulation of Corin Gene Expression in Hypertrophic Cardiomyocytes and Failing Myocardium
  American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2004  |   Pubmed ID: 15191894
• Inhibition of P38 MAPK Decreases Myocardial TNF-alpha Expression and Improves Myocardial Function and Survival in Endotoxemia
  Cardiovascular Research. Oct, 2003  |   Pubmed ID: 14553829
• Endothelial Nitric-oxide Synthase Enhances Lipopolysaccharide-stimulated Tumor Necrosis Factor-alpha Expression Via CAMP-mediated P38 MAPK Pathway in Cardiomyocytes
  The Journal of Biological Chemistry. Mar, 2003  |   Pubmed ID: 12506117
• Deficiency in Endothelial Nitric Oxide Synthase Impairs Myocardial Angiogenesis
  American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2002  |   Pubmed ID: 12388304
• Development of Heart Failure and Congenital Septal Defects in Mice Lacking Endothelial Nitric Oxide Synthase
  Circulation. Aug, 2002  |   Pubmed ID: 12176963
• Early and Persistent Activation of Myocardial Apoptosis, Bax and Caspases: Insights into Mechanisms of Progression of Heart Failure
  Pathophysiology : the Official Journal of the International Society for Pathophysiology / ISP. Jun, 2002  |   Pubmed ID: 12039650