Xiaoxin Chen

Publications

• Novel Resveratrol-Based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity
  Journal of Medicinal Chemistry. Aug, 2015  |   Pubmed ID: 26204233
• Personalized Targeted Therapy for Esophageal Squamous Cell Carcinoma
  World Journal of Gastroenterology : WJG. Jul, 2015  |   Pubmed ID: 26167067
• The Recyclable Synthesis of Hierarchical Zeolite SAPO-34 with Excellent MTO Catalytic Performance
  Chemical Communications (Cambridge, England). Jul, 2015  |   Pubmed ID: 26121259
• Quantitative Risk Stratification of Oral Leukoplakia with Exfoliative Cytology
  PloS One. 2015  |   Pubmed ID: 25978541
• A Case of Late-onset Riboflavin Responsive Multiple Acyl-CoA Dehydrogenase Deficiency (MADD) with a Novel Mutation in ETFDH Gene
  Journal of the Neurological Sciences. Jun, 2015  |   Pubmed ID: 25913573
• Mycoplasma Pneumonia Combined with Pulmonary Infarction in a Child
  International Journal of Clinical and Experimental Medicine. 2015  |   Pubmed ID: 25785159
• Molecular Mechanisms of Ethanol-associated Oro-esophageal Squamous Cell Carcinoma
  Cancer Letters. Jun, 2015  |   Pubmed ID: 25766659
• Surveying Mercury Levels in Hair, Blood and Urine of Under 7-year Old Children from a Coastal City in China
  International Journal of Environmental Research and Public Health. Nov, 2014  |   Pubmed ID: 25419876
• Translational Research on Barrett's Esophagus
  Annals of the New York Academy of Sciences. Sep, 2014  |   Pubmed ID: 25266024
• Pharmacological Effects of the Water Fraction of Key Components in the Traditional Chinese Prescription Mai Tong Fang on 3T3-L1 Adipocytes and Ob/ob Diabetic Mice
  Molecules (Basel, Switzerland). 2014  |   Pubmed ID: 25230123
• Ginger Compound [6]-shogaol and Its Cysteine-conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo
  Chemical Research in Toxicology. Sep, 2014  |   Pubmed ID: 25148906
• Markers of Eosinophilic Inflammation for Diagnosis of Eosinophilic Esophagitis and Proton Pump Inhibitor-responsive Esophageal Eosinophilia: a Prospective Study
  Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Dec, 2014  |   Pubmed ID: 24993367
• Anti-tumor Activity and Safety Evaluation of Fisetin-loaded Methoxy Poly(ethylene Glycol)-poly(epsilon-caprolactone) Nanoparticles
  Journal of Biomedical Nanotechnology. Apr, 2014  |   Pubmed ID: 24734510
• Identification and Pharmacokinetics of Novel Alkylresorcinol Metabolites in Human Urine, New Candidate Biomarkers for Whole-grain Wheat and Rye Intake
  The Journal of Nutrition. Feb, 2014  |   Pubmed ID: 24259554
• Single Nucleotide Polymorphisms of Caudal Type Homeobox 1 and 2 Are Associated with Barrett's Esophagus
  Digestive Diseases and Sciences. Jan, 2014  |   Pubmed ID: 23918153
• Nrf2 Deficiency Impairs the Barrier Function of Mouse Oesophageal Epithelium
  Gut. May, 2014  |   Pubmed ID: 23676441
• NFkB and Nrf2 in Esophageal Epithelial Barrier Function
  Tissue Barriers. Dec, 2013  |   Pubmed ID: 24790804
• Tissue Resistance in the Normal and Diseased Esophagus
  Annals of the New York Academy of Sciences. Oct, 2013  |   Pubmed ID: 24117643
• Cellular Origins and Molecular Mechanisms of Barrett's Esophagus and Esophageal Adenocarcinoma
  Annals of the New York Academy of Sciences. Oct, 2013  |   Pubmed ID: 24117642
• Transgenic Overexpression of Cdx1b Induces Metaplastic Changes of Gene Expression in Zebrafish Esophageal Squamous Epithelium
  Zebrafish. Jun, 2013  |   Pubmed ID: 23672288
• Synthesis, Characterization, and Application of Amino-terminated Poly(ethylene Glycol)-block-poly(epsilon-caprolactone) Copolymer for Paclitaxel
  Journal of Nanoscience and Nanotechnology. Jan, 2013  |   Pubmed ID: 23646699
• Gastroesophageal Reflux Activates the NF-κB Pathway and Impairs Esophageal Barrier Function in Mice
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2013  |   Pubmed ID: 23639809
• Cysteine-conjugated Metabolite of Ginger Component [6]-shogaol Serves As a Carrier of [6]-shogaol in Cancer Cells and in Mice
  Chemical Research in Toxicology. Jun, 2013  |   Pubmed ID: 23638641
• Two Novel Nanoscale Preparations of Micelle and Thermosensitive Hydrogel for Docetaxel to Treat Malignant Tumor
  Journal of Biomedical Nanotechnology. Mar, 2013  |   Pubmed ID: 23620990
• G Protein-coupled Receptor Kinase 6 Deficiency Promotes Angiogenesis, Tumor Progression, and Metastasis
  Journal of Immunology (Baltimore, Md. : 1950). May, 2013  |   Pubmed ID: 23589623
• Sox2 Cooperates with Inflammation-mediated Stat3 Activation in the Malignant Transformation of Foregut Basal Progenitor Cells
  Cell Stem Cell. Mar, 2013  |   Pubmed ID: 23472872
• Characterization of Thiol-conjugated Metabolites of Ginger Components Shogaols in Mouse and Human Urine and Modulation of the Glutathione Levels in Cancer Cells by [6]-shogaol
  Molecular Nutrition & Food Research. Mar, 2013  |   Pubmed ID: 23322393
• Intestinal Metaplasia Recurs Infrequently in Patients Successfully Treated for Barrett's Esophagus with Radiofrequency Ablation
  The American Journal of Gastroenterology. Feb, 2013  |   Pubmed ID: 23247578
• Safety and Efficacy of Endoscopic Mucosal Therapy with Radiofrequency Ablation for Patients with Neoplastic Barrett's Esophagus
  Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Jun, 2013  |   Pubmed ID: 23103824
• Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced Hamster Cheek Pouch Carcinogenesis by a 5-lipoxygenase Inhibitor, Garcinol
  Nutrition and Cancer. 2012  |   Pubmed ID: 23137051
• 6-gingerdiols As the Major Metabolites of 6-gingerol in Cancer Cells and in Mice and Their Cytotoxic Effects on Human Cancer Cells
  Journal of Agricultural and Food Chemistry. Nov, 2012  |   Pubmed ID: 23066935
• Diagnostic Utility of Major Basic Protein, Eotaxin-3, and Leukotriene Enzyme Staining in Eosinophilic Esophagitis
  The American Journal of Gastroenterology. Oct, 2012  |   Pubmed ID: 22777338
• Focal Endoscopic Mucosal Resection Before Radiofrequency Ablation is Equally Effective and Safe Compared with Radiofrequency Ablation Alone for the Eradication of Barrett's Esophagus with Advanced Neoplasia
  Gastrointestinal Endoscopy. Oct, 2012  |   Pubmed ID: 22732872
• Transcript Profiling Identifies Dynamic Gene Expression Patterns and an Important Role for Nrf2/Keap1 Pathway in the Developing Mouse Esophagus
  PloS One. 2012  |   Pubmed ID: 22567161
• Hedgehog Signaling Activation in the Development of Squamous Cell Carcinoma and Adenocarcinoma of Esophagus
  International Journal of Biochemistry and Molecular Biology. 2012  |   Pubmed ID: 22509480
• Review: Experimental Models for Barrett's Esophagus and Esophageal Adenocarcinoma
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Jun, 2012  |   Pubmed ID: 22421618
• The Decreased Expression of Beclin-1 Correlates with Progression to Esophageal Adenocarcinoma: the Role of Deoxycholic Acid
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2012  |   Pubmed ID: 22301112
• Metabolism of [6]-shogaol in Mice and in Cancer Cells
  Drug Metabolism and Disposition: the Biological Fate of Chemicals. Apr, 2012  |   Pubmed ID: 22246389
• Time-selective Chemoprevention of Vitamin E and Selenium on Esophageal Carcinogenesis in Rats: the Possible Role of Nuclear Factor KappaB Signaling Pathway
  International Journal of Cancer. Journal International Du Cancer. Oct, 2012  |   Pubmed ID: 22223226
• Molecular Mechanisms of Barrett's Esophagus
  Digestive Diseases and Sciences. Dec, 2011  |   Pubmed ID: 21984436
• Molecular Mechanisms of Barrett's Esophagus and Adenocarcinoma
  Annals of the New York Academy of Sciences. Sep, 2011  |   Pubmed ID: 21950830
• Molecular Aspects of Esophageal Development
  Annals of the New York Academy of Sciences. Sep, 2011  |   Pubmed ID: 21950820
• Structural Identification of Mouse Fecal Metabolites of Theaflavin 3,3'-digallate Using Liquid Chromatography Tandem Mass Spectrometry
  Journal of Chromatography. A. Oct, 2011  |   Pubmed ID: 21906744
• Ethanol Promotes Chemically Induced Oral Cancer in Mice Through Activation of the 5-lipoxygenase Pathway of Arachidonic Acid Metabolism
  Cancer Prevention Research (Philadelphia, Pa.). Nov, 2011  |   Pubmed ID: 21881027
• Chemopreventive Effects of Early-stage and Late-stage Supplementation of Vitamin E and Selenium on Esophageal Carcinogenesis in Rats Maintained on a Low Vitamin E/selenium Diet
  Carcinogenesis. Mar, 2011  |   Pubmed ID: 21186300
• Tryptase Staining of Mast Cells May Differentiate Eosinophilic Esophagitis from Gastroesophageal Reflux Disease
  The American Journal of Gastroenterology. Feb, 2011  |   Pubmed ID: 20978486
• Structural Identification of Mouse Urinary Metabolites of Pterostilbene Using Liquid Chromatography/tandem Mass Spectrometry
  Rapid Communications in Mass Spectrometry : RCM. Jun, 2010  |   Pubmed ID: 20499322
• Varying Phenotypes in Swine Versus Murine Transgenic Models Constitutively Expressing the Same Human Sonic Hedgehog Transcriptional Activator, K5-HGLI2 Delta N
  Transgenic Research. Oct, 2010  |   Pubmed ID: 20099029
• Chemoprevention of Oral Cancer in Animal Models, and Effect on Leukoplakias in Human Patients with ZengShengPing, a Mixture of Medicinal Herbs
  Oral Oncology. Feb, 2010  |   Pubmed ID: 20022553
• Zebrafish K5 Promoter Driven GFP Expression As a Transgenic System for Oral Research
  Oral Oncology. Jan, 2010  |   Pubmed ID: 19932050
• Stimuli-responsive Wettability of Nonplanar Substrates: PH-controlled Floatation and Supporting Force
  Langmuir : the ACS Journal of Surfaces and Colloids. Jan, 2010  |   Pubmed ID: 19639980
• Detecting Precancerous Lesions in the Hamster Cheek Pouch Using Spectroscopic White-light Optical Coherence Tomography to Assess Nuclear Morphology Via Spectral Oscillations
  Journal of Biomedical Optics. Nov-Dec, 2009  |   Pubmed ID: 20059268
• Gastroesophageal Reflux Leads to Esophageal Cancer in a Surgical Model with Mice
  BMC Gastroenterology. 2009  |   Pubmed ID: 19627616
• Differential Gene Expression in Normal Esophagus and Barrett's Esophagus
  Journal of Gastroenterology. 2009  |   Pubmed ID: 19468668
• Effect of Alpha-tocopherol, N-acetylcysteine and Omeprazole on Esophageal Adenocarcinoma Formation in a Rat Surgical Model
  International Journal of Cancer. Journal International Du Cancer. Mar, 2009  |   Pubmed ID: 19058177
• Zyflamend Reduces LTB4 Formation and Prevents Oral Carcinogenesis in a 7,12-dimethylbenz[alpha]anthracene (DMBA)-induced Hamster Cheek Pouch Model
  Carcinogenesis. Nov, 2008  |   Pubmed ID: 18687669
• Depletion of Beta-arrestin-2 Promotes Tumor Growth and Angiogenesis in a Murine Model of Lung Cancer
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008  |   Pubmed ID: 18390755
• Multilayered Epithelium in a Rat Model and Human Barrett's Esophagus: Similar Expression Patterns of Transcription Factors and Differentiation Markers
  BMC Gastroenterology. 2008  |   Pubmed ID: 18190713
• Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced Oral Carcinogenesis in Hamster Cheek Pouch by Topical Application of a Dual Inhibitor of Epidermal Growth Factor Receptor (EGFR) and ErbB2 Tyrosine Kinases
  Oral Oncology. Jul, 2008  |   Pubmed ID: 17936675
• Identification of Arsenic-binding Proteins in Human Breast Cancer Cells
  Cancer Letters. Sep, 2007  |   Pubmed ID: 17499915
• Regulation of Cdx2 Expression by Promoter Methylation, and Effects of Cdx2 Transfection on Morphology and Gene Expression of Human Esophageal Epithelial Cells
  Carcinogenesis. Feb, 2007  |   Pubmed ID: 16990345
• Five-lipoxygenase Pathway of Arachidonic Acid Metabolism in Carcino-genesis and Cancer Chemoprevention
  Current Cancer Drug Targets. Nov, 2006  |   Pubmed ID: 17100567
• Determination of Endogenous Tissue Inflammation Profiles by LC/MS/MS: COX- and LOX-derived Bioactive Lipids
  Prostaglandins, Leukotrienes, and Essential Fatty Acids. Dec, 2006  |   Pubmed ID: 17011176
• Development of an Immunocytokine, IL-2-183B2scFv, for Targeted Immunotherapy of Ovarian Cancer
  Gynecologic Oncology. Dec, 2006  |   Pubmed ID: 16806435
• Involvement of the 5-lipoxygenase/leukotriene A4 Hydrolase Pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced Oral Carcinogenesis in Hamster Cheek Pouch, and Inhibition of Carcinogenesis by Its Inhibitors
  Carcinogenesis. Sep, 2006  |   Pubmed ID: 16632477
• Selection of Topically Applied Non-steroidal Anti-inflammatory Drugs for Oral Cancer Chemoprevention
  Oral Oncology. Jul, 2005  |   Pubmed ID: 15975519
• Overexpression of 5-lipoxygenase and Cyclooxygenase 2 in Hamster and Human Oral Cancer and Chemopreventive Effects of Zileuton and Celecoxib
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2005  |   Pubmed ID: 15756036
• 5-リポキシゲナーゼ ラットとひと食道腺癌および抑制性発癌に及ぼす Zileuton とセレコキシブの過剰発現
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2004  |   Pubmed ID: 15475461
• Phenotype of Columnar-lined Esophagus in Rats with Esophagogastroduodenal Anastomosis: Similarity to Human Barrett's Esophagus
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Jun, 2004  |   Pubmed ID: 15094711
• Modulation of Arachidonic Acid Metabolism by Curcumin and Related Beta-diketone Derivatives: Effects on Cytosolic Phospholipase A(2), Cyclooxygenases and 5-lipoxygenase
  Carcinogenesis. Sep, 2004  |   Pubmed ID: 15073046
• Leukotriene A4 Hydrolase in Rat and Human Esophageal Adenocarcinomas and Inhibitory Effects of Bestatin
  Journal of the National Cancer Institute. Jul, 2003  |   Pubmed ID: 12865451
• [Chemopreventive Effect of Tea and Curcumin on DMBA-induced Oral Carcinogenesis in Hamsters]
  Wei Sheng Yan Jiu = Journal of Hygiene Research. Oct, 2002  |   Pubmed ID: 12572355
• Aberrant Arachidonic Acid Metabolism in Esophageal Adenocarcinogenesis, and the Effects of Sulindac, Nordihydroguaiaretic Acid, and Alpha-difluoromethylornithine on Tumorigenesis in a Rat Surgical Model
  Carcinogenesis. Dec, 2002  |   Pubmed ID: 12507933
• Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced Oral Carcinogenesis in Hamsters by Tea and Curcumin
  Carcinogenesis. Aug, 2002  |   Pubmed ID: 12151348
• Overexpression of Glucose-regulated Protein 94 (Grp94) in Esophageal Adenocarcinomas of a Rat Surgical Model and Humans
  Carcinogenesis. Jan, 2002  |   Pubmed ID: 11756233