Xin-zhuan Su

Publications

• Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria
  ACS Medicinal Chemistry Letters. Feb, 2012  |   Pubmed ID: 22328964
• Directional Gene Expression and Antisense Transcripts in Sexual and Asexual Stages of Plasmodium Falciparum
  BMC Genomics. 2011  |   Pubmed ID: 22129310
• Macrophage Migration Inhibitory Factor Homolog from Plasmodium Yoelii Modulates Monocyte Recruitment and Activation in Spleen During Infection
  Parasitology Research. Oct, 2011  |   Pubmed ID: 22015474
• A New Malaria Antigen Produces Partial Protection Against Plasmodium Yoelii Challenge
  Parasitology Research. Sep, 2011  |   Pubmed ID: 21915626
• Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets
  Science (New York, N.Y.). Aug, 2011  |   Pubmed ID: 21817045
• Linkage Maps from Multiple Genetic Crosses and Loci Linked to Growth-related Virulent Phenotype in Plasmodium Yoelii
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011  |   Pubmed ID: 21690382
• Population Genetic Analysis of Plasmodium Falciparum Parasites Using a Customized Illumina GoldenGate Genotyping Assay
  PloS One. 2011  |   Pubmed ID: 21673999
• Challenges and Prospects for Malaria Elimination in the Greater Mekong Subregion
  Acta Tropica. Apr, 2011  |   Pubmed ID: 21515238
• Discovery of New Antimalarial Chemotypes Through Chemical Methodology and Library Development
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011  |   Pubmed ID: 21498685
• High Recombination Rates and Hotspots in a Plasmodium Falciparum Genetic Cross
  Genome Biology. 2011  |   Pubmed ID: 21463505
• Malaria in the Greater Mekong Subregion: Heterogeneity and Complexity
  Acta Tropica. Mar, 2011  |   Pubmed ID: 21382335
• Effect of PCR Extension Temperature on High-throughput Sequencing
  Molecular and Biochemical Parasitology. Mar, 2011  |   Pubmed ID: 21112355
• Recent Progress in Functional Genomic Research in Plasmodium Falciparum
  Current Genomics. Jun, 2010  |   Pubmed ID: 21119892
• Lack of Allele-specific Efficacy of a Bivalent AMA1 Malaria Vaccine
  Malaria Journal. 2010  |   Pubmed ID: 20565971
• Use of Magnetically Purified Plasmodium Falciparum Parasites Improves the Accuracy of Erythrocyte Invasion Assays
  Experimental Parasitology. Oct, 2010  |   Pubmed ID: 20493844
• Human Malaria Parasites: Are We Ready for a New Species?
  The Journal of Infectious Diseases. May, 2010  |   Pubmed ID: 20380563
• Increased Tolerance to Artemisinin in Plasmodium Falciparum is Mediated by a Quiescence Mechanism
  Antimicrobial Agents and Chemotherapy. May, 2010  |   Pubmed ID: 20160056
• Plasmodium Falciparum Genome-wide Scans for Positive Selection, Recombination Hot Spots and Resistance to Antimalarial Drugs
  Nature Genetics. Mar, 2010  |   Pubmed ID: 20101240
• Discovery, Mechanisms of Action and Combination Therapy of Artemisinin
  Expert Review of Anti-infective Therapy. Oct, 2009  |   Pubmed ID: 19803708
• Genetic Mapping of Targets Mediating Differential Chemical Phenotypes in Plasmodium Falciparum
  Nature Chemical Biology. Oct, 2009  |   Pubmed ID: 19734910
• Large-scale Genotyping and Genetic Mapping in Plasmodium Parasites
  The Korean Journal of Parasitology. Jun, 2009  |   Pubmed ID: 19488413
• Hundreds of Microsatellites for Genotyping Plasmodium Yoelii Parasites
  Molecular and Biochemical Parasitology. Aug, 2009  |   Pubmed ID: 19450732
• Disruption of a Plasmodium Falciparum Multidrug Resistance-associated Protein (PfMRP) Alters Its Fitness and Transport of Antimalarial Drugs and Glutathione
  The Journal of Biological Chemistry. Mar, 2009  |   Pubmed ID: 19117944
• Drug Resistance and Genetic Mapping in Plasmodium Falciparum
  Current Genetics. Nov, 2008  |   Pubmed ID: 18802698
• Detection of Genome-wide Polymorphisms in the AT-rich Plasmodium Falciparum Genome Using a High-density Microarray
  BMC Genomics. 2008  |   Pubmed ID: 18724869
• Effects of Plasmodium Falciparum Mixed Infections on in Vitro Antimalarial Drug Tests and Genotyping
  The American Journal of Tropical Medicine and Hygiene. Aug, 2008  |   Pubmed ID: 18689621
• Genome-wide Compensatory Changes Accompany Drug- Selected Mutations in the Plasmodium Falciparum Crt Gene
  PloS One. 2008  |   Pubmed ID: 18575593
• Population Structure of the Genes Encoding the Polymorphic Plasmodium Falciparum Apical Membrane Antigen 1: Implications for Vaccine Design
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2008  |   Pubmed ID: 18515425
• Histone Acetyltransferase Inhibitor Anacardic Acid Causes Changes in Global Gene Expression During in Vitro Plasmodium Falciparum Development
  Eukaryotic Cell. Jul, 2008  |   Pubmed ID: 18487348
• Changes in the Plasmodial Surface Anion Channel Reduce Leupeptin Uptake and Can Confer Drug Resistance in Plasmodium Falciparum-infected Erythrocytes
  Antimicrobial Agents and Chemotherapy. Jul, 2008  |   Pubmed ID: 18443109
• Local Adaptation and Vector-mediated Population Structure in Plasmodium Vivax Malaria
  Molecular Biology and Evolution. Jun, 2008  |   Pubmed ID: 18385220
• Diversity and Evolution of the Rhoph1/clag Multigene Family of Plasmodium Falciparum
  Molecular and Biochemical Parasitology. Mar, 2008  |   Pubmed ID: 18155305
• Structural Polymorphism and Diversifying Selection on the Pregnancy Malaria Vaccine Candidate VAR2CSA
  Molecular and Biochemical Parasitology. Oct, 2007  |   Pubmed ID: 17669514
• CDNA Sequences Reveal Considerable Gene Prediction Inaccuracy in the Plasmodium Falciparum Genome
  BMC Genomics. 2007  |   Pubmed ID: 17662120
• Typing Plasmodium Yoelii Microsatellites Using a Simple and Affordable Fluorescent Labeling Method
  Molecular and Biochemical Parasitology. Oct, 2007  |   Pubmed ID: 17658627
• PfGCN5-mediated Histone H3 Acetylation Plays a Key Role in Gene Expression in Plasmodium Falciparum
  Eukaryotic Cell. Jul, 2007  |   Pubmed ID: 17449656
• Genome-wide Variation and Identification of Vaccine Targets in the Plasmodium Falciparum Genome
  Nature Genetics. Jan, 2007  |   Pubmed ID: 17159981
• CD4+ T-cell Response to Mitochondrial Cytochrome B in Human Melanoma
  Cancer Research. Jun, 2006  |   Pubmed ID: 16740732
• Global Genetic Diversity and Evolution of Var Genes Associated with Placental and Severe Childhood Malaria
  Molecular and Biochemical Parasitology. Aug, 2006  |   Pubmed ID: 16697476
• Upregulation of Expression of the Reticulocyte Homology Gene 4 in the Plasmodium Falciparum Clone Dd2 is Associated with a Switch in the Erythrocyte Invasion Pathway
  Molecular and Biochemical Parasitology. Feb, 2006  |   Pubmed ID: 16289357
• Disruption of a Plasmodium Falciparum Gene Linked to Male Sexual Development Causes Early Arrest in Gametocytogenesis
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005  |   Pubmed ID: 16275909
• Recombination Hotspots and Population Structure in Plasmodium Falciparum
  PLoS Biology. Oct, 2005  |   Pubmed ID: 16144426
• Host Switch Leads to Emergence of Plasmodium Vivax Malaria in Humans
  Molecular Biology and Evolution. Aug, 2005  |   Pubmed ID: 15858201
• Genetic Mapping in the Human Malaria Parasite Plasmodium Falciparum
  Molecular Microbiology. Sep, 2004  |   Pubmed ID: 15341640
• Pfcrt Polymorphism and the Spread of Chloroquine Resistance in Plasmodium Falciparum Populations Across the Amazon Basin
  The Journal of Infectious Diseases. Jul, 2004  |   Pubmed ID: 15216481
• Dissecting the Loci of Low-level Quinine Resistance in Malaria Parasites
  Molecular Microbiology. May, 2004  |   Pubmed ID: 15130119
• Polymorphism in the Plasmodium Falciparum Erythrocyte-binding Ligand JESEBL/EBA-181 Alters Its Receptor Specificity
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004  |   Pubmed ID: 14983041
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  Molecular and Biochemical Parasitology. Jan, 2004  |   Pubmed ID: 14668019
• The "Malaria's Eve" Hypothesis and the Debate Concerning the Origin of the Human Malaria Parasite Plasmodium Falciparum
  Microbes and Infection / Institut Pasteur. Aug, 2003  |   Pubmed ID: 12919857
• Multiple Transporters Associated with Malaria Parasite Responses to Chloroquine and Quinine
  Molecular Microbiology. Aug, 2003  |   Pubmed ID: 12890022
• Single-nucleotide Polymorphisms and Genome Diversity in Plasmodium Vivax
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003  |   Pubmed ID: 12799466
• Early Origin and Recent Expansion of Plasmodium Falciparum
  Science (New York, N.Y.). Apr, 2003  |   Pubmed ID: 12690197
• Polymorphism in a Plasmodium Falciparum Erythrocyte-binding Ligand Changes Its Receptor Specificity
  The Journal of Experimental Medicine. Dec, 2002  |   Pubmed ID: 12461087
• Microsatellite Analysis in Plasmodium Falciparum
  Methods in Molecular Medicine. 2002  |   Pubmed ID: 12125109
• Chromosome-wide SNPs Reveal an Ancient Origin for Plasmodium Falciparum
  Nature. Jul, 2002  |   Pubmed ID: 12124624
• Genetic Diversity and Chloroquine Selective Sweeps in Plasmodium Falciparum
  Nature. Jul, 2002  |   Pubmed ID: 12124623
• Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium Falciparum
  Molecular Pharmacology. Jan, 2002  |   Pubmed ID: 11752204