Other Publications (1)
Articles by Ying Nie in JoVE
A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy Xiaoliang Wang*1, Muhammad A. Chaudhry*2, Ying Nie2, Zijian Xie1, Joseph I. Shapiro2, Jiang Liu1,2 1Marshall Institute for Interdisciplinary Research (MIIR), Marshall University, 2Department of Biomedical Sciences, Marshall University Joan C. Edwards School of Medicine This manuscript provides a detailed two-step surgical procedure to perform mouse 5/6th partial nephrectomy (PNx) with pole ligation. Four weeks after surgery, in comparison with sham-operated mice, the PNx mice developed impaired renal function, anemia, cardiac hypertrophy, cardiac fibrosis, and decreased heart systolic and diastolic function.
Other articles by Ying Nie on PubMed
Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress Antioxidants (Basel, Switzerland). | Pubmed ID: 28257114 Other than genetic regulation of salt sensitivity of blood pressure, many factors have been shown to regulate renal sodium handling which contributes to long-term blood pressure regulation and have been extensively reviewed. Here we present our progress on the Na/K-ATPase signaling mediated sodium reabsorption in renal proximal tubules, from cardiotonic steroids-mediated to reactive oxygen species (ROS)-mediated Na/K-ATPase signaling that contributes to experimental salt sensitivity.