yolande Richard

Depatment of Infection,Immunity and Inflammation

Cochin Institute

yolande Richard
Research director

During her PhD in Cellular and Molecular genetics obtained in 1980 at the University Pierre & Marie Curie, Yolande Richard has identified new discrete thymus T-cell subsets and established a correspondence with lymphoblastic T-cell lymphoma in children, with major consequences on therapeutic strategies. Thanks to collaboration between teams of A. Bernard (Head of her PhD Team) and of S. Schlossman (Harvard Medical School, Boston), she participated to the characterisation of pioneer monoclonal antibodies founding the classification into Clusters of Differentiation. She obtained a position at CNRS in 1981 and then focused her activity on helper vs. suppressive functions of T-cells. In 1983, she moved to the P. Galanaud’ s INSERM Unit where she studied the heterogeneity of human B-cells towards antigens, cytokines and cognate interactions with T-cells and identified a new receptor for a B-cell growth factor. In 1987, she obtained a Doctorate in Life Sciences (Immunology speciality). From 1992 to 2005, she headed teams working on B-cell phenotypes and functions in physiological and pathological settings. From 2006 to 2010, she joined the Laboratory of Immuno-Virology (iMETI) at CEA where she initiated a study on tissue B-cell abnormalities during SIV infection, as an animal model for HIV infection. Last, she joined the Cochin Institute in 2011 working on impairments of plasmacytoid dendritic cells and B-cell responses in SIV/HIV infection and Multiple Sclerosis, with a particular emphasis on the cytokine BAFF (for B-cell activating factor of the TNF family).

• ORCID Number: 0000-0001-8560-9250


Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue

1Institute of Molecular Virology, Ulm University Medical Center, 2CNRS UMR-8601, Centre Interdisciplinaire Chimie Biologie, 3Team Chemistry & Biology, Modeling & Immunology for Therapy, Université Paris Descartes, 4Université Paris Descartes, Sorbonne Paris Cité, 5Pediatric Otolaryngology Department, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, 6Université de Paris, Institut Cochin

JoVE 60914

 Immunology and Infection