You Wan Neuroscience Research Institute, Key Lab for Neuroscience, Ministry of Education/National Health Commission Peking University Biography Publications Institution JoVE Articles You Wan has not added a biography. If you are You Wan and would like to personalize this page please email our Author Liaison for assistance. Publications Anterior Cingulate Cortex Modulates the Affective-motivative Dimension of Hyperosmolality-induced Thirst The Journal of Physiology. Aug, 2019 | Pubmed ID: 31390064 Upregulation of Interleukin-6 on Ca3.2 T-type Calcium Channels in Dorsal Root Ganglion Neurons Contributes to Neuropathic Pain in Rats with Spinal Nerve Ligation Experimental Neurology. Jul, 2019 | Pubmed ID: 30872136 Upregulation of Ca3.2 T-type Calcium Channels in Adjacent Intact L4 Dorsal Root Ganglion Neurons in Neuropathic Pain Rats with L5 Spinal Nerve Ligation Neuroscience Research. May, 2019 | Pubmed ID: 29684385 Elevated Resting State Gamma Oscillatory Activities in Electroencephalogram of Patients With Post-herpetic Neuralgia Frontiers in Neuroscience. 2018 | Pubmed ID: 30405337 Decreased Abundance of TRESK Two-pore Domain Potassium Channels in Sensory Neurons Underlies the Pain Associated with Bone Metastasis Science Signaling. Oct, 2018 | Pubmed ID: 30327410 Electrophysiological Signature of Pain Advances in Experimental Medicine and Biology. 2018 | Pubmed ID: 30306524 A Context-Based Analgesia Model in Rats: Involvement of Prefrontal Cortex Neuroscience Bulletin. Dec, 2018 | Pubmed ID: 30178433 Histidine Alleviates Impairments Induced by Chronic Cerebral Hypoperfusion in Mice Frontiers in Physiology. 2018 | Pubmed ID: 29930513 Heteromerization of μ-opioid Receptor and Cholecystokinin B Receptor Through the Third Transmembrane Domain of the μ-opioid Receptor Contributes to the Anti-opioid Effects of Cholecystokinin Octapeptide Experimental & Molecular Medicine. 05, 2018 | Pubmed ID: 29780163 Neural Pathways in Medial Septal Cholinergic Modulation of Chronic Pain: Distinct Contribution of the Anterior Cingulate Cortex and Ventral Hippocampus Pain. Aug, 2018 | Pubmed ID: 29624516 Hypersensitivity of Prelimbic Cortex Neurons Contributes to Aggravated Nociceptive Responses in Rats With Experience of Chronic Inflammatory Pain Frontiers in Molecular Neuroscience. 2018 | Pubmed ID: 29623029 Increased Expression of Ca3.2 T-type Calcium Channels in Damaged DRG Neurons Contributes to Neuropathic Pain in Rats with Spared Nerve Injury Molecular Pain. Jan-Dec, 2018 | Pubmed ID: 29592785 Accumulation of Ca3.2 T-type Calcium Channels in the Uninjured Sural Nerve Contributes to Neuropathic Pain in Rats with Spared Nerve Injury Frontiers in Molecular Neuroscience. 2018 | Pubmed ID: 29472842 Cholinergic Neurons in Medial Septum Maintain Anxiety-like Behaviors Induced by Chronic Inflammatory Pain Neuroscience Letters. 04, 2018 | Pubmed ID: 29410218 Formaldehyde Induces Diabetes-associated Cognitive Impairments FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 07, 2018 | Pubmed ID: 29401634 Activation of CRF/CRFR1 Signaling in the Basolateral Nucleus of the Amygdala Contributes to Chronic Forced Swim-induced Depressive-like Behaviors in Rats Behavioural Brain Research. 02, 2018 | Pubmed ID: 29080675 Extracting Neural Oscillation Signatures of Laser-Induced Nociception in Pain-Related Regions in Rats Frontiers in Neural Circuits. 2017 | Pubmed ID: 29062273 Mapping the Information Trace in Local Field Potentials by a Computational Method of Two-Dimensional Time-Shifting Synchronization Likelihood Based on Graphic Processing Unit Acceleration Neuroscience Bulletin. Dec, 2017 | Pubmed ID: 28900900 Brain-derived Neurotrophic Factor in the Infralimbic Cortex Alleviates Inflammatory Pain Neuroscience Letters. Aug, 2017 | Pubmed ID: 28648456 Adult Hippocampal Neurogenesis Along the Dorsoventral Axis Contributes Differentially to Environmental Enrichment Combined with Voluntary Exercise in Alleviating Chronic Inflammatory Pain in Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 04, 2017 | Pubmed ID: 28292830 Chronic Stress Exacerbates Neuropathic Pain Via the Integration of Stress-affect-related Information with Nociceptive Information in the Central Nucleus of the Amygdala Pain. 04, 2017 | Pubmed ID: 28225710 Reduced GABAergic Transmission in the Ventrobasal Thalamus Contributes to Thermal Hyperalgesia in Chronic Inflammatory Pain Scientific Reports. 02, 2017 | Pubmed ID: 28150719 Anxiolytic Effects of Hippocampal Neurosteroids in Normal and Neuropathic Rats with Spared Nerve Injury Journal of Neurochemistry. 04, 2017 | Pubmed ID: 28129443 Inhibiting Medial Septal Cholinergic Neurons with DREADD Alleviated Anxiety-like Behaviors in Mice Neuroscience Letters. 01, 2017 | Pubmed ID: 27939976 Enhanced Gamma Oscillatory Activity in Rats with Chronic Inflammatory Pain Frontiers in Neuroscience. 2016 | Pubmed ID: 27847461 Elevated Neurosteroids in the Lateral Thalamus Relieve Neuropathic Pain in Rats with Spared Nerve Injury Neuroscience Bulletin. Aug, 2016 | Pubmed ID: 27325509 Maladaptive Plasticity and Neuropathic Pain Neural Plasticity. 2016 | Pubmed ID: 26925270 New Mechanism of Bone Cancer Pain: Tumor Tissue-Derived Endogenous Formaldehyde Induced Bone Cancer Pain Via TRPV1 Activation Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 26900062 Effect of Transcutaneous Acupoint Electrical Stimulation on Propofol Sedation: an Electroencephalogram Analysis of Patients Undergoing Pituitary Adenomas Resection BMC Complementary and Alternative Medicine. Jan, 2016 | Pubmed ID: 26817460 Hippocampal Neurogenesis: Does It Relieve or Worsen Chronic Pain? Pain. Feb, 2016 | Pubmed ID: 26797509 Randomised Controlled Trial of Contralateral Manual Acupuncture for the Relief of Chronic Shoulder Pain Acupuncture in Medicine : Journal of the British Medical Acupuncture Society. Jun, 2016 | Pubmed ID: 26795764 Cortical Activities of Heat-sensitization Responses in Suspended Moxibustion: an EEG Source Analysis with SLORETA Cognitive Neurodynamics. Dec, 2015 | Pubmed ID: 26557928 Aging-associated Formaldehyde-induced Norepinephrine Deficiency Contributes to Age-related Memory Decline Aging Cell. Aug, 2015 | Pubmed ID: 25866202 Shp-1 Dephosphorylates TRPV1 in Dorsal Root Ganglion Neurons and Alleviates CFA-induced Inflammatory Pain in Rats Pain. Apr, 2015 | Pubmed ID: 25790452 BDNF Contributes to the Development of Neuropathic Pain by Induction of Spinal Long-term Potentiation Via SHP2 Associated GluN2B-containing NMDA Receptors Activation in Rats with Spinal Nerve Ligation Neurobiology of Disease. Jan, 2015 | Pubmed ID: 25447233 Functional Upregulation of Nav1.8 Sodium Channels on the Membrane of Dorsal Root Ganglia Neurons Contributes to the Development of Cancer-induced Bone Pain PloS One. 2014 | Pubmed ID: 25503076 Sensitization of Neurons in the Central Nucleus of the Amygdala Via the Decreased GABAergic Inhibition Contributes to the Development of Neuropathic Pain-related Anxiety-like Behaviors in Rats Molecular Brain. Oct, 2014 | Pubmed ID: 25277376 Characterizing Heat-sensitization Responses in Suspended Moxibustion with High-density EEG Pain Medicine (Malden, Mass.). Aug, 2014 | Pubmed ID: 25132308 Exacerbation of Tonic but Not Phasic Pain by Entorhinal Cortex Lesions Neuroscience Letters. Oct, 2014 | Pubmed ID: 24840135 The Induction of Long-term Potentiation in Spinal Dorsal Horn After Peripheral Nociceptive Stimulation and Contribution of Spinal TRPV1 in Rats Neuroscience. Jun, 2014 | Pubmed ID: 24680883 Basolateral Amygdala Lesion Inhibits the Development of Pain Chronicity in Neuropathic Pain Rats PloS One. 2013 | Pubmed ID: 23940666 Comparison of Electroacupuncture in Restrained and Unrestrained Rat Models Evidence-based Complementary and Alternative Medicine : ECAM. 2013 | Pubmed ID: 23737830 Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain Evidence-based Complementary and Alternative Medicine : ECAM. 2013 | Pubmed ID: 23710210 Upregulation of P2X3 Receptors by Neuronal Calcium Sensor Protein VILIP-1 in Dorsal Root Ganglions Contributes to the Bone Cancer Pain in Rats Pain. Sep, 2013 | Pubmed ID: 23707265 Aging-associated Excess Formaldehyde Leads to Spatial Memory Deficits Scientific Reports. 2013 | Pubmed ID: 23657727 Lysine-specific Demethylase 1 in Breast Cancer Cells Contributes to the Production of Endogenous Formaldehyde in the Metastatic Bone Cancer Pain Model of Rats PloS One. 2013 | Pubmed ID: 23516587 Suppression of KCNQ/M (Kv7) Potassium Channels in Dorsal Root Ganglion Neurons Contributes to the Development of Bone Cancer Pain in a Rat Model Pain. Dec, 2012 | Pubmed ID: 23352759 Formaldehyde Increases Intracellular Calcium Concentration in Primary Cultured Hippocampal Neurons Partly Through NMDA Receptors and T-type Calcium Channels Neuroscience Bulletin. Dec, 2012 | Pubmed ID: 23160928 Spatiotemporally Controlled Co-delivery of Anti-vasculature Agent and Cytotoxic Drug by Octreotide-modified Stealth Liposomes Pharmaceutical Research. Oct, 2012 | Pubmed ID: 22723122 Enhanced Excitability of Small Dorsal Root Ganglion Neurons in Rats with Bone Cancer Pain Molecular Pain. Apr, 2012 | Pubmed ID: 22472208 Formaldehyde Up-regulates TRPV1 Through MAPK and PI3K Signaling Pathways in a Rat Model of Bone Cancer Pain Neuroscience Bulletin. Apr, 2012 | Pubmed ID: 22466127 Vesicular Glutamate Transporter-3 Contributes to Visceral Hyperalgesia Induced by Trichinella Spiralis Infection in Rats Digestive Diseases and Sciences. Apr, 2012 | Pubmed ID: 22160634 Activation of Satellite Glial Cells in Lumbar Dorsal Root Ganglia Contributes to Neuropathic Pain After Spinal Nerve Ligation Brain Research. Jan, 2012 | Pubmed ID: 22050959 Anterior Cingulate Cortex is Crucial for Contra- but Not Ipsi-lateral Electro-acupuncture in the Formalin-induced Inflammatory Pain Model of Rats Molecular Pain. Aug, 2011 | Pubmed ID: 21854647 Phase-amplitude Coupling Between θ and γ Oscillations During Nociception in Rat Electroencephalography Neuroscience Letters. Jul, 2011 | Pubmed ID: 21640788 Electrophysiological Properties of Spinal Wide Dynamic Range Neurons in Neuropathic Pain Rats Following Spinal Nerve Ligation Neuroscience Bulletin. Feb, 2011 | Pubmed ID: 21270898 Tumor Tissue-derived Formaldehyde and Acidic Microenvironment Synergistically Induce Bone Cancer Pain PloS One. Apr, 2010 | Pubmed ID: 20422007 Decrease in the Descending Inhibitory 5-HT System in Rats with Spinal Nerve Ligation Brain Research. May, 2010 | Pubmed ID: 20230801 Contribution of the Spinal Cord BDNF to the Development of Neuropathic Pain by Activation of the NR2B-containing NMDA Receptors in Rats with Spinal Nerve Ligation Experimental Neurology. Apr, 2010 | Pubmed ID: 20079352 Electroacupuncture Analgesia is Enhanced in Transgenic Nociceptin/orphanin FQ Knock-out Mice Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences. Jun, 2009 | Pubmed ID: 19727226 Role of the Spinal Cord NR2B-containing NMDA Receptors in the Development of Neuropathic Pain Experimental Neurology. Feb, 2009 | Pubmed ID: 19046970 The Role of TRPV1 in Different Subtypes of Dorsal Root Ganglion Neurons in Rat Chronic Inflammatory Nociception Induced by Complete Freund's Adjuvant Molecular Pain. 2008 | Pubmed ID: 19055783 Involvement of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channels in Dorsal Root Ganglion in Neuropathic Pain Sheng Li Xue Bao : [Acta Physiologica Sinica]. Oct, 2008 | Pubmed ID: 18958363 [Descending Facilitation System and Its Role in the Development of Neuropathic Pain] Sheng Li Ke Xue Jin Zhan [Progress in Physiology]. Apr, 2008 | Pubmed ID: 18664170 Behavioral and Electrophysiological Evidence for the Differential Functions of TRPV1 at Early and Late Stages of Chronic Inflammatory Nociception in Rats Neurochemical Research. Oct, 2008 | Pubmed ID: 18512150 Characteristics of HCN Channels and Their Participation in Neuropathic Pain Neurochemical Research. Oct, 2008 | Pubmed ID: 18461446 Role of Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) Receptor Subunit GluR1 in Spinal Dorsal Horn in Inflammatory Nociception and Neuropathic Nociception in Rat Brain Research. Mar, 2008 | Pubmed ID: 18289517 Axonal Accumulation of Hyperpolarization-activated Cyclic Nucleotide-gated Cation Channels Contributes to Mechanical Allodynia After Peripheral Nerve Injury in Rat Pain. Jul, 2008 | Pubmed ID: 18179873 The Neuroscience Research Institute at Peking University: a Place for the Solution of Pain and Drug Abuse Cellular and Molecular Neurobiology. Jan, 2008 | Pubmed ID: 18058018 Long-term Synaptic Plasticity in the Spinal Dorsal Horn and Its Modulation by Electroacupuncture in Rats with Neuropathic Pain Experimental Neurology. Dec, 2007 | Pubmed ID: 17936754 Roles of 5-hydroxytryptamine (5-HT) Receptor Subtypes in the Inhibitory Effects of 5-HT on C-fiber Responses of Spinal Wide Dynamic Range Neurons in Rats The Journal of Pharmacology and Experimental Therapeutics. Jun, 2007 | Pubmed ID: 17329553 Peripheral Formalin Injection Induces Long-lasting Increases in Cyclooxygenase 1 Expression by Microglia in the Spinal Cord The Journal of Pain : Official Journal of the American Pain Society. Feb, 2007 | Pubmed ID: 16949875 CCL2 and CXCL1 Trigger Calcitonin Gene-related Peptide Release by Exciting Primary Nociceptive Neurons Journal of Neuroscience Research. Oct, 2005 | Pubmed ID: 16047385 Inhibition of Hyperpolarization-activated Current by ZD7288 Suppresses Ectopic Discharges of Injured Dorsal Root Ganglion Neurons in a Rat Model of Neuropathic Pain Brain Research. Jan, 2005 | Pubmed ID: 15680942 Ketamine Enhances the Efficacy to and Delays the Development of Tolerance to Electroacupuncture-induced Antinociception in Rats Neuroscience Letters. Feb, 2005 | Pubmed ID: 15670657 Ectopic Discharges from Injured Nerve Fibers Are Highly Correlated with Tactile Allodynia Only in Early, but Not Late, Stage in Rats with Spinal Nerve Ligation Experimental Neurology. Jan, 2005 | Pubmed ID: 15589519 Changes of Hypothalamic Alpha-MSH and CART Peptide Expression in Diet-induced Obese Rats Peptides. Dec, 2004 | Pubmed ID: 15572204 [In Vitro Experimental Study of the Effects of Different Introcular Irrigating Solutions on the Viability of Rat Retinal Neuron Cells] [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology. Jul, 2004 | Pubmed ID: 15454059 Ketamine Potentiates the Effect of Electroacupuncture on Mechanical Allodynia in a Rat Model of Neuropathic Pain Neuroscience Letters. Sep, 2004 | Pubmed ID: 15364421 Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channels: Roles in the Differential Electrophysiological Properties of Rat Primary Afferent Neurons Journal of Neuroscience Research. Jun, 2004 | Pubmed ID: 15139030 Attenuation of Mechanical but Not Thermal Hyperalgesia by Electroacupuncture with the Involvement of Opioids in Rat Model of Chronic Inflammatory Pain Brain Research Bulletin. Mar, 2004 | Pubmed ID: 15130698 Adenovirus-mediated Delivery of GDNF Ameliorates Corticospinal Neuronal Atrophy and Motor Function Deficits in Rats with Spinal Cord Injury Neuroreport. Mar, 2004 | Pubmed ID: 15094497 Change of Vanilloid Receptor 1 Expression in Dorsal Root Ganglion and Spinal Dorsal Horn During Inflammatory Nociception Induced by Complete Freund's Adjuvant in Rats Neuroreport. Mar, 2004 | Pubmed ID: 15094470 Suppression of Neuropathic Pain by Peripheral Electrical Stimulation in Rats: Mu-opioid Receptor and NMDA Receptor Implicated Experimental Neurology. May, 2004 | Pubmed ID: 15081584 [Electroacupuncture of 2 Hz Induces Long-term Depression of Synaptic Transmission in the Spinal Dorsal Horn in Rats with Neuropathic Pain] Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences. Oct, 2003 | Pubmed ID: 14601297 Nocistatin Potentiates Electroacupuncture Antinociceptive Effects and Reverses Chronic Tolerance to Electroacupuncture in Mice Neuroscience Letters. Oct, 2003 | Pubmed ID: 12972161 [Changes in Long-term Synaptic Plasticity in the Spinal Dorsal Horn of Neuropathic Pain Rats] Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences. Jun, 2003 | Pubmed ID: 12914234 [Capsaicin and Its Receptor--vanilloid Receptor] Sheng Li Ke Xue Jin Zhan [Progress in Physiology]. Jan, 2003 | Pubmed ID: 12778802 Characteristics of Electroacupuncture-induced Analgesia in Mice: Variation with Strain, Frequency, Intensity and Opioid Involvement Brain Research. Jul, 2002 | Pubmed ID: 12113947 Bruk av in vivo single-fiber Recording og intakt rygg rot Ganglion med vedlagt ischias nerven til å undersøke mekanismen for Lednings feil Honghui Mao*1,2, Xiuchao Wang*1,3, Wen Chen4, FengYu Liu5, You Wan5, Sanjue Hu1, Junling Xing1,6 1Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, 2Department of Toxicology, School of Public Health, ShanXi Medical University, 3Department of Psychology, Fourth Military Medical University, 4Department of Neurobiology, School of Basic Medical Sciences, Advanced Innovation Center for Human Brain Protection, Capital Medical University, 5Neuroscience Research Institute, Key Lab for Neuroscience, Ministry of Education/National Health Commission, Peking University, 6Department of Radiation Biology, Faculty of Preventive Medicine, Fourth Military Medical University JoVE 59234 Neuroscience Samtidig opptak av kortikale lokale feltet potensialer og Electrocorticograms svar på Nociceptive Laser Stimuli fra fritt flytte rotter Lupeng Yue1,2, Fengrui Zhang3, Xuejing Lu1,2, You Wan4,5,6, Li Hu1,2,7 1CAS Key Laboratory of Mental Health, Institute of Psychology, 2Department of Psychology, University of Chinese Academy of Sciences, 3Research Center of Brain Cognitive Neuroscience, Liaoning Normal University, 4Neuroscience Research Institute, Peking University, 5Department of Neurobiology, School of Basic Medical Sciences, Peking University, 6Key Laboratory for Neuroscience, Ministry of Education/National Health and Family Planning Commission, Peking University, 7Department of Pain Management, State Key Clinical Specialty in Pain Medicine, Second Affiliated Hospital of Guangzhou Medical University JoVE 58686 Behavior
Bruk av in vivo single-fiber Recording og intakt rygg rot Ganglion med vedlagt ischias nerven til å undersøke mekanismen for Lednings feil Honghui Mao*1,2, Xiuchao Wang*1,3, Wen Chen4, FengYu Liu5, You Wan5, Sanjue Hu1, Junling Xing1,6 1Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, 2Department of Toxicology, School of Public Health, ShanXi Medical University, 3Department of Psychology, Fourth Military Medical University, 4Department of Neurobiology, School of Basic Medical Sciences, Advanced Innovation Center for Human Brain Protection, Capital Medical University, 5Neuroscience Research Institute, Key Lab for Neuroscience, Ministry of Education/National Health Commission, Peking University, 6Department of Radiation Biology, Faculty of Preventive Medicine, Fourth Military Medical University JoVE 59234 Neuroscience
Samtidig opptak av kortikale lokale feltet potensialer og Electrocorticograms svar på Nociceptive Laser Stimuli fra fritt flytte rotter Lupeng Yue1,2, Fengrui Zhang3, Xuejing Lu1,2, You Wan4,5,6, Li Hu1,2,7 1CAS Key Laboratory of Mental Health, Institute of Psychology, 2Department of Psychology, University of Chinese Academy of Sciences, 3Research Center of Brain Cognitive Neuroscience, Liaoning Normal University, 4Neuroscience Research Institute, Peking University, 5Department of Neurobiology, School of Basic Medical Sciences, Peking University, 6Key Laboratory for Neuroscience, Ministry of Education/National Health and Family Planning Commission, Peking University, 7Department of Pain Management, State Key Clinical Specialty in Pain Medicine, Second Affiliated Hospital of Guangzhou Medical University JoVE 58686 Behavior
