Youngjoo Kwon

Publications

• Neuroprotective Effect of Undecylenic Acid Extracted from Ricinus Communis L. Through Inhibition of μ-calpain
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Feb, 2012  |   Pubmed ID: 22333440
• Dihydroxylated 2,4,6-triphenyl Pyridines: Synthesis, Topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure-activity Relationship Study
  European Journal of Medicinal Chemistry. Jan, 2012  |   Pubmed ID: 22318164
• 2,4-Diaryl-5,6-dihydro-1,10-phenanthroline and 2,4-diaryl-5,6-dihydrothieno[2,3-h] Quinoline Derivatives for Topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure-activity Relationship Study
  Bioorganic Chemistry. Feb, 2012  |   Pubmed ID: 22000119
• Synthesis of Benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines Via Ring Closing Metathesis and Evaluation of Topoisomerase I Inhibitory Activity, Cytotoxicity and Docking Study
  Bioorganic & Medicinal Chemistry. Sep, 2011  |   Pubmed ID: 21873069
• Design and Synthesis of 4-amino-2-phenylquinazolines As Novel Topoisomerase I Inhibitors with Molecular Modeling
  Bioorganic & Medicinal Chemistry. Jul, 2011  |   Pubmed ID: 21684168
• Synthesis of 2,4-diaryl Chromenopyridines and Evaluation of Their Topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure-activity Relationship
  European Journal of Medicinal Chemistry. Aug, 2011  |   Pubmed ID: 21601964
• Differential Expressions of Adhesive Molecules and Proteases Define Mechanisms of Ovarian Tumor Cell Matrix Penetration/invasion
  PloS One. 2011  |   Pubmed ID: 21526198
• Design and Evaluation of Variants of the Protein Transduction Domain Originated from Translationally Controlled Tumor Protein
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. May, 2011  |   Pubmed ID: 21440624
• Synthesis and Anti-melanogenic Activity of Hydroxyphenyl Benzyl Ether Analogues
  Bioorganic & Medicinal Chemistry. Apr, 2011  |   Pubmed ID: 21429753
• Synthesis, Biological Evaluation, and Molecular Docking Study of 3-(3'-heteroatom Substituted-2'-hydroxy-1'-propyloxy) Xanthone Analogues As Novel Topoisomerase IIα Catalytic Inhibitor
  European Journal of Medicinal Chemistry. Jun, 2011  |   Pubmed ID: 21419530
• A Peptide Binding to Dimerized Translationally Controlled Tumor Protein Modulates Allergic Reactions
  Journal of Molecular Medicine (Berlin, Germany). Jun, 2011  |   Pubmed ID: 21384150
• Design, Synthesis and Docking Study of 5-amino Substituted Indeno[1,2-c]isoquinolines As Novel Topoisomerase I Inhibitors
  Bioorganic & Medicinal Chemistry. Mar, 2011  |   Pubmed ID: 21353568
• Rapid and Reliable Measurement for Evaluating Directly the Reactivity of N-Acetylcysteine with Glucose Degradation Products in Peritoneal Dialysis Fluids
  Analytical Chemistry. Feb, 2011  |   Pubmed ID: 21299245
• Methyl Gallate Exhibits Potent Antitumor Activities by Inhibiting Tumor Infiltration of CD4+CD25+ Regulatory T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2010  |   Pubmed ID: 21048105
• Synthesis and Biological Properties of Benzo-annulated Rutaecarpines
  Biological & Pharmaceutical Bulletin. 2010  |   Pubmed ID: 20930379
• Synthesis and Pharmacological Evaluation of New Methyloxiranylmethoxyxanthone Analogues
  European Journal of Medicinal Chemistry. Sep, 2010  |   Pubmed ID: 20619511
• Mutations in SOHLH1 Gene Associate with Nonobstructive Azoospermia
  Human Mutation. Jul, 2010  |   Pubmed ID: 20506135
• Synthesis, Topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure-activity Relationship Study of Hydroxylated 2,4-diphenyl-6-aryl Pyridines
  Bioorganic & Medicinal Chemistry. May, 2010  |   Pubmed ID: 20392646
• Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl Pyridine Derivatives and Evaluation of Their Topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure-activity Relationship
  Bioorganic & Medicinal Chemistry. Mar, 2010  |   Pubmed ID: 20188578
• New Benzoxanthone Derivatives As Topoisomerase Inhibitors and DNA Cross-linkers
  Bioorganic & Medicinal Chemistry. Feb, 2010  |   Pubmed ID: 20093033
• 2,6-Dithienyl-4-furyl Pyridines: Synthesis, Topoisomerase I and II Inhibition, Cytotoxicity, Structure-activity Relationship, and Docking Study
  Bioorganic & Medicinal Chemistry Letters. Jan, 2010  |   Pubmed ID: 19954977
• 2-Thienyl-4-furyl-6-aryl Pyridine Derivatives: Synthesis, Topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure-activity Relationship Study
  Bioorganic & Medicinal Chemistry. Jan, 2010  |   Pubmed ID: 19939682
• Oxiranylmethyloxy or Thiiranylmethyloxy-azaxanthones and -acridone Analogues As Potential Topoisomerase I Inhibitors
  Bioorganic & Medicinal Chemistry Letters. Dec, 2009  |   Pubmed ID: 19836231
• Synthesis of Isoquinolinone-based Tetracycles As Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitors
  Bioorganic & Medicinal Chemistry. Nov, 2009  |   Pubmed ID: 19800803
• A Small Molecule That Blocks Fat Synthesis by Inhibiting the Activation of SREBP
  Chemistry & Biology. Aug, 2009  |   Pubmed ID: 19716478
• A Concise Synthesis of Licochalcone E and Its Regio-isomer, Licochalcone F
  Chemical & Pharmaceutical Bulletin. Jun, 2009  |   Pubmed ID: 19483343
• Identification of 3-acetyl-2-aminoquinolin-4-one As a Novel, Nonpeptidic Scaffold for Specific Calpain Inhibitory Activity
  Journal of Medicinal Chemistry. May, 2009  |   Pubmed ID: 19419206
• Molecular Design, Synthesis and Docking Study of Benz[b]oxepines and 12-oxobenzo[c]phenanthridinones As Topoisomerase 1 Inhibitors
  Bioorganic & Medicinal Chemistry Letters. May, 2009  |   Pubmed ID: 19345580
• Wrenchnolol Derivative Optimized for Gene Activation in Cells
  Journal of the American Chemical Society. Apr, 2009  |   Pubmed ID: 19290630
• Age-related Differential Responses to Curcumin-induced Apoptosis During the Initiation of Colon Cancer in Rats
  Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Feb, 2009  |   Pubmed ID: 19095035
• A Rapid and Sensitive Screening System for Human Type I Collagen with the Aim of Discovering Potent Anti-aging or Anti-fibrotic Compounds
  Molecules and Cells. Dec, 2008  |   Pubmed ID: 18810249
• 2,2-dimethyl-2H-pyran-derived Alkaloids I. Practical Synthesis of Acronycine and Benzo[b]acronycine and Their Biological Properties
  Archives of Pharmacal Research. Sep, 2008  |   Pubmed ID: 18806949
• Ovarian Normal and Tumor-associated Fibroblasts Retain in Vivo Stromal Characteristics in a 3-D Matrix-dependent Manner
  Gynecologic Oncology. Jul, 2008  |   Pubmed ID: 18448156
• New Insight for Fluoroquinophenoxazine Derivatives As Possibly New Potent Topoisomerase I Inhibitor
  Bioorganic & Medicinal Chemistry Letters. Feb, 2008  |   Pubmed ID: 18178085
• First Synthesis of 4'-selenonucleosides Showing Unusual Southern Conformation
  Organic Letters. Jan, 2008  |   Pubmed ID: 18088134
• Aging Alters Acute Apoptotic Response to Azoxymethane in the Colon of Rats
  Experimental Gerontology. Dec, 2007  |   Pubmed ID: 17961945
• Convenient Synthesis of Indeno[1,2-c]isoquinolines As Constrained Forms of 3-arylisoquinolines and Docking Study of a Topoisomerase I Inhibitor into DNA-topoisomerase I Complex
  Bioorganic & Medicinal Chemistry Letters. Nov, 2007  |   Pubmed ID: 17827007
• Design, Docking, and Synthesis of Novel Indeno[1,2-c]isoquinolines for the Development of Antitumor Agents As Topoisomerase I Inhibitors
  Bioorganic & Medicinal Chemistry Letters. Jul, 2007  |   Pubmed ID: 17498951
• Modulation of P-glycoprotein-mediated Resistance by Kaempferol Derivatives Isolated from Zingiber Zerumbet
  Phytotherapy Research : PTR. Jun, 2007  |   Pubmed ID: 17335117
• P-glycoprotein Inhibitory Activity of Two Phenolic Compounds, (-)-syringaresinol and Tricin from Sasa Borealis
  Chemistry & Biodiversity. Jan, 2007  |   Pubmed ID: 17256728
• Polyproline-rod Approach to Isolating Protein Targets of Bioactive Small Molecules: Isolation of a New Target of Indomethacin
  Journal of the American Chemical Society. Jan, 2007  |   Pubmed ID: 17243824
• Synthesis of New Xanthone Analogues and Their Biological Activity Test--cytotoxicity, Topoisomerase II Inhibition, and DNA Cross-linking Study
  Bioorganic & Medicinal Chemistry Letters. Mar, 2007  |   Pubmed ID: 17194586
• Effect of Azoxymethane and Curcumin on Transcriptional Levels of Cyclooxygenase-1 and -2 During Initiation of Colon Carcinogenesis
  Scandinavian Journal of Gastroenterology. Jan, 2007  |   Pubmed ID: 17190766
• Anthocyanin-rich Extracts Inhibit Multiple Biomarkers of Colon Cancer in Rats
  Nutrition and Cancer. 2006  |   Pubmed ID: 16800776
• Study on the Synthesis and Cytotoxicity of New Quinophenoxazine Derivatives
  Chemical & Pharmaceutical Bulletin. Feb, 2006  |   Pubmed ID: 16462076
• Small Molecule Transcription Factor Mimic
  Journal of the American Chemical Society. Dec, 2004  |   Pubmed ID: 15584709
• Inhibition of Colonic Aberrant Crypt Foci by Curcumin in Rats is Affected by Age
  Nutrition and Cancer. 2004  |   Pubmed ID: 15203376
• A Wrench-shaped Synthetic Molecule That Modulates a Transcription Factor-coactivator Interaction
  Journal of the American Chemical Society. Mar, 2004  |   Pubmed ID: 15025473
• New Complex of Post-activated Neocarzinostatin Chromophore with DNA: Bulge DNA Binding from the Minor Groove
  Biochemistry. Feb, 2003  |   Pubmed ID: 12564921
• Induced Formation of a DNA Bulge Structure by a Molecular Wedge Ligand-postactivated Neocarzinostatin Chromophore
  Biochemistry. Apr, 2002  |   Pubmed ID: 11955061