In JoVE (1)

Other Publications (1)

Articles by Yuchao Xu in JoVE

Other articles by Yuchao Xu on PubMed

Predictive Value of GSTP1 Ile105Val Polymorphism in Clinical Outcomes of Chemotherapy in Gastric and Colorectal Cancers: a Systematic Review and Meta-analysis

Cancer Chemotherapy and Pharmacology. 06, 2016  |  Pubmed ID: 27154175

Gastric and colorectal cancers remain the major causes of cancer-related death with a bad prognosis. Up to now, platinum combined with fluoropyrimidines has been most commonly used in chemotherapy regimens of gastric and colorectal cancers. Recently, a series of studies have been conducted to investigate the associations of biomarkers, such as GSTP1 Ile105Val polymorphism, with the chemotherapy efficacy in gastric and colorectal cancers; however, the results were not consistent and inconclusive. Here, we performed a systematic review and meta-analysis to summarize the associations of GSTP1 Ile105Val polymorphism with the chemotherapy efficacy in gastric and colorectal cancers.

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