Yuuki Imai

Publications

• Periostin Increased by Mechanical Stress Upregulates Interleukin-6 Expression in the Ligamentum Flavum
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2023  |   Pubmed ID: 36583686
• Effect of Hormonal Therapy on the Otoconial Changes Caused by Estrogen Deficiency
  Scientific Reports. Dec, 2022  |   Pubmed ID: 36585504
• Deletion of Tfam in Prx1-Cre Expressing Limb Mesenchyme Results in Spontaneous Bone Fractures
  Journal of Bone and Mineral Metabolism. Sep, 2022  |   Pubmed ID: 35947192
• Induction of IPSC-derived Prg4-positive Cells with Characteristics of Superficial Zone Chondrocytes and Fibroblast-like Synovial Cells
  BMC Molecular and Cell Biology. Jul, 2022  |   Pubmed ID: 35870887
• Reduced Dynamic Loads Due to Hip Dislocation Induce Acetabular Cartilage Degeneration by IL-6 and MMP3 Via the STAT3/periostin/NF-κB Axis
  Scientific Reports. Jul, 2022  |   Pubmed ID: 35842459
• Epigenetic Regulator UHRF1 Orchestrates Proinflammatory Gene Expression in Rheumatoid Arthritis in a Suppressive Manner
  The Journal of Clinical Investigation. Jun, 2022  |   Pubmed ID: 35472067
• Uhrf1 Governs the Proliferation and Differentiation of Muscle Satellite Cells
  IScience. Mar, 2022  |   Pubmed ID: 35243267
• Novel Animal Model of Soft Tissue Tumor Due to Aberrant Hedgehog Signaling Activation in Pericyte Lineage
  Cell and Tissue Research. Apr, 2022  |   Pubmed ID: 35072792
• Histone H3K27 Demethylase, Utx, Regulates Osteoblast-to-osteocyte Differentiation
  Biochemical and Biophysical Research Communications. Jan, 2022  |   Pubmed ID: 34974301
• Macrophages Are Requisite for Angiogenesis of Type H Vessels During Bone Regeneration in Mice
  Bone. Jan, 2022  |   Pubmed ID: 34534711
• Estrogen Receptor α in Mature Osteoblasts Regulates the Late Stage of Bone Regeneration
  Biochemical and Biophysical Research Communications. Jun, 2021  |   Pubmed ID: 33964733
• Myofiber Androgen Receptor Increases Muscle Strength Mediated by a Skeletal Muscle Splicing Variant of Mylk4
  IScience. Apr, 2021  |   Pubmed ID: 33870126
• Topical Co-administration of Zoledronate with Recombinant Human Bone Morphogenetic Protein-2 Can Induce and Maintain Bone Formation in the Bone Marrow Environment
  BMC Musculoskeletal Disorders. Jan, 2021  |   Pubmed ID: 33472600
• DNA Maintenance Methylation Enzyme Dnmt1 in Satellite Cells is Essential for Muscle Regeneration
  Biochemical and Biophysical Research Communications. Jan, 2021  |   Pubmed ID: 33310192
• Reprogramming of Synovial Macrophage Metabolism by Synovial Fibroblasts Under Inflammatory Conditions
  Cell Communication and Signaling : CCS. Nov, 2020  |   Pubmed ID: 33256735
• Estrogen Receptor β Controls Muscle Growth and Regeneration in Young Female Mice
  Stem Cell Reports. Sep, 2020  |   Pubmed ID: 32822588
• The Musculoskeletal Knowledge Portal: Making Omics Data Useful to the Broader Scientific Community
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Sep, 2020  |   Pubmed ID: 32777102
• Hedgehog Inhibitors Suppress Osteoclastogenesis in In Vitro Cultures, and Deletion of in Macrophage/Osteoclast Lineage Prevents Age-Related Bone Loss
  International Journal of Molecular Sciences. Apr, 2020  |   Pubmed ID: 32326611
• Evaluation of the Structure of the Otoconial Layer Using Micro-computed Tomography
  Auris, Nasus, Larynx. Oct, 2020  |   Pubmed ID: 32173170
• GPRC5A Facilitates Cell Proliferation Through Cell Cycle Regulation and Correlates with Bone Metastasis in Prostate Cancer
  International Journal of Cancer. Mar, 2020  |   Pubmed ID: 31276604
• Recent Insights into Long Bone Development: Central Role of Hedgehog Signaling Pathway in Regulating Growth Plate
  International Journal of Molecular Sciences. Nov, 2019  |   Pubmed ID: 31757091
• Micro-CT Imaging Analysis for the Effects of Ibandronate and Eldecalcitol on Secondary Osteoporosis and Arthritis in Adjuvant-induced Arthritis Rats
  Biomedical Research (Tokyo, Japan). 2019  |   Pubmed ID: 31597905
• The E3 Ubiquitin Ligase MIB2 Enhances Inflammation by Degrading the Deubiquitinating Enzyme CYLD
  The Journal of Biological Chemistry. Sep, 2019  |   Pubmed ID: 31366726
• A Simple Mouse Model of Pericardial Adhesions
  Journal of Cardiothoracic Surgery. Jun, 2019  |   Pubmed ID: 31253183
• Fibroblast Growth Factor 9 Is Upregulated Upon Intervertebral Mechanical Stress-Induced Ligamentum Flavum Hypertrophy in a Rabbit Model
  Spine. Oct, 2019  |   Pubmed ID: 31022154
• The Effects of Resistance Training on Bone Mineral Density and Bone Quality in Type 2 Diabetic Rats
  Physiological Reports. 03, 2019  |   Pubmed ID: 30916457
• Zscan10 Suppresses Osteoclast Differentiation by Regulating Expression of Haptoglobin
  Bone. May, 2019  |   Pubmed ID: 30771488
• Histone H3K27 Demethylase Negatively Controls the Memory Formation of Antigen-Stimulated CD8 T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2019  |   Pubmed ID: 30626691
• [ASBMR 2018 Report on Basic Research.]
  Clinical Calcium. 2019  |   Pubmed ID: 30590367
• Raman Spectroscopic Analysis to Detect Reduced Bone Quality After Sciatic Neurectomy in Mice
  Molecules (Basel, Switzerland). Nov, 2018  |   Pubmed ID: 30477282
• The Tumor Suppressor Menin Prevents Effector CD8 T-cell Dysfunction by Targeting MTORC1-dependent Metabolic Activation
  Nature Communications. Aug, 2018  |   Pubmed ID: 30120246
• Growth Plate-derived Hedgehog-signal-responsive Cells Provide Skeletal Tissue Components in Growing Bone
  Histochemistry and Cell Biology. Apr, 2018  |   Pubmed ID: 29356962
• DANFIN Functions As an Inhibitor of Transcription Factor NF-κB and Potentiates the Antitumor Effect of Bortezomib in Multiple Myeloma
  Biochemical and Biophysical Research Communications. 01, 2018  |   Pubmed ID: 29284118
• Uhrf1 is Indispensable for Normal Limb Growth by Regulating Chondrocyte Differentiation Through Specific Gene Expression
  Development (Cambridge, England). Jan, 2018  |   Pubmed ID: 29180567
• The HIV Co-receptor CCR5 Regulates Osteoclast Function
  Nature Communications. Dec, 2017  |   Pubmed ID: 29263385
• Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head
  Scientific Reports. Nov, 2017  |   Pubmed ID: 29118346
• [Calcium and Bone Metabolism Across Women's Life Stages. Molecular Mechanisms Underlying Bone Metabolism by Estrogen.]
  Clinical Calcium. 2017  |   Pubmed ID: 28439051
• The CUL3-SPOP-DAXX Axis is a Novel Regulator of VEGFR2 Expression in Vascular Endothelial Cells
  Scientific Reports. Feb, 2017  |   Pubmed ID: 28216678
• Hydroxylation of Methylated DNA by TET1 in Chondrocyte Differentiation of C3H10T1/2 Cells
  Biochemistry and Biophysics Reports. Mar, 2016  |   Pubmed ID: 28955815
• Local Co-application of Zoledronate Promotes Long-term Maintenance of Newly Formed Bone Induced by Recombinant Human Bone Morphogenetic Protein 2
  Biochemical and Biophysical Research Communications. Nov, 2016  |   Pubmed ID: 27746180
• [Epigenetic Regulation by Androgen Receptor and Possible Function in Bone Metabolism]
  Clinical Calcium. Jul, 2016  |   Pubmed ID: 27346313
• Identification of Nedd9 As a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis
  PloS One. 2016  |   Pubmed ID: 27336669
• SFRP4-dependent Wnt Signal Modulation is Critical for Bone Remodeling During Postnatal Development and Age-related Bone Loss
  Scientific Reports. Apr, 2016  |   Pubmed ID: 27117872
• [Application of Big Data Analyses for Musculoskeletal Cell Differentiation]
  Clinical Calcium. Apr, 2016  |   Pubmed ID: 27013628
• Fatostatin, an SREBP Inhibitor, Prevented RANKL-induced Bone Loss by Suppression of Osteoclast Differentiation
  Biochimica Et Biophysica Acta. Nov, 2015  |   Pubmed ID: 26319416
• [Analysis of Musculoskeletal Systems and Their Diseases. Sex Hormone Receptors Dependent Gene Expression Mechanisms in Locomotive Tissues]
  Clinical Calcium. Aug, 2015  |   Pubmed ID: 26224671
• Aryl Hydrocarbon Receptor Catabolic Activity in Bone Metabolism is Osteoclast Dependent in Vivo
  Biochemical and Biophysical Research Communications. Jul, 2014  |   Pubmed ID: 24938130
• Pctaire1/Cdk16 Promotes Skeletal Myogenesis by Inducing Myoblast Migration and Fusion
  FEBS Letters. Aug, 2014  |   Pubmed ID: 24931367
• [Bone Metabolism by Sex Hormones and Gonadotropins]
  Clinical Calcium. Jun, 2014  |   Pubmed ID: 24870831
• Netrin-4 Derived from Murine Vascular Endothelial Cells Inhibits Osteoclast Differentiation in Vitro and Prevents Bone Loss in Vivo
  FEBS Letters. Jun, 2014  |   Pubmed ID: 24846137
• Nonmyocytic Androgen Receptor Regulates the Sexually Dimorphic Development of the Embryonic Bulbocavernosus Muscle
  Endocrinology. Jul, 2014  |   Pubmed ID: 24742196
• Identification of Novel Transcription Factors in Osteoclast Differentiation Using Genome-wide Analysis of Open Chromatin Determined by DNase-seq
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2014  |   Pubmed ID: 24677342
• Estrogen Receptor α in Osteocytes Regulates Trabecular Bone Formation in Female Mice
  Bone. Mar, 2014  |   Pubmed ID: 24333171
• [Regulation of Bone Metabolisms by Estrogen/estrogen Receptors Signaling]
  Clinical Calcium. Nov, 2013  |   Pubmed ID: 24162602
• Novel Insights into Histone Modifiers in Adipogenesis
  Adipocyte. Oct, 2013  |   Pubmed ID: 24052908