Zachary D. Dalebroux

Department of Microbiology and Immunology

University of Oklahoma Health Sciences Center

Zachary D. Dalebroux
Assistant Professor

My lab studies Gram-negative bacteria. We focus is on understanding the role of the outer membrane lipid bilayer in promoting antibiotic resistance and disease pathogenesis. Our attention centers on defining key proteins, lipids, and mechanisms for Salmonella enterica serovars like S. Typhimurium, S. Typhi and S. Paratyphi. These pathogens which cause gastroenteritis and systemic disease in humans and regulate the the phospholipid and glycolipid (lipopolysaccharides, or LPS) components of the outer membrane unto survive in the mammalian host environment. We are interested defining mechanisms of salmonellae LPS and phospholipid regulation and determining the regulated lipid changes that influence host innate-immune response to salmonellae.

Publications

एसिनेटोबैक्टर बौमैनी के लिए तकनीकी समायोजन के साथ इनर और बाहरी झिल्ली अंशों में ग्राम-नकारात्मक बैक्टीरिया के लिए सेल लिफाफे का पृथक्करण

1Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center

JoVE 60517

 Immunology and Infection