Zeev Estrov Department of Leukemia The University of Texas MD Anderson Cancer Center Biography Publications Institution JoVE Articles Zeev Estrov has not added a biography. If you are Zeev Estrov and would like to personalize this page please email our Author Liaison for assistance. Publications At High Levels, Constitutively Activated STAT3 Induces Apoptosis of Chronic Lymphocytic Leukemia Cells Journal of Immunology (Baltimore, Md. : 1950). May, 2016 | Pubmed ID: 27076684 Autoimmune Cytopenias in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib Haematologica. Jun, 2016 | Pubmed ID: 27013651 Clinical Implications of TP53 Mutations in Myelodysplastic Syndromes Treated with Hypomethylating Agents Oncotarget. Mar, 2016 | Pubmed ID: 26871476 Philadelphia-positive Dimorphic Blasts in Mixed-phenotype Acute Leukemia with TET2 Mutation American Journal of Hematology. Jun, 2016 | Pubmed ID: 26799924 Clofarabine Plus Low-Dose Cytarabine Is As Effective As and Less Toxic Than Intensive Chemotherapy in Elderly AML Patients Clinical Lymphoma, Myeloma & Leukemia. Mar, 2016 | Pubmed ID: 26752456 Impact of BCR-ABL Transcript Type on Outcome in Patients with Chronic-phase CML Treated with Tyrosine Kinase Inhibitors Blood. Mar, 2016 | Pubmed ID: 26729897 Metabolism Pathways in Chronic Lymphocytic Leukemia Leukemia & Lymphoma. Apr, 2016 | Pubmed ID: 26643954 β2 -microglobulin Normalization Within 6 Months of Ibrutinib-based Treatment is Associated with Superior Progression-free Survival in Patients with Chronic Lymphocytic Leukemia Cancer. Feb, 2016 | Pubmed ID: 26588193 Minimal Residual Disease Assessed by Multi-parameter Flow Cytometry is Highly Prognostic in Adult Patients with Acute Lymphoblastic Leukaemia British Journal of Haematology. Feb, 2016 | Pubmed ID: 26492205 Synchronous Del5q Myelodysplastic Syndrome (del5qMDS) and Adult B-cell Acute Lymphoblastic Leukemia (B-ALL) with TET2 and TP53 Mutations American Journal of Hematology. Mar, 2016 | Pubmed ID: 26437693 Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasms Concurrently Diagnosed: Clinical and Biological Characteristics Leukemia & Lymphoma. May, 2016 | Pubmed ID: 26402369 Secondary Solid Tumors and Lymphoma in Patients with Essential Thrombocythemia and Polycythemia Vera - Single Center Experience Leukemia & Lymphoma. 2016 | Pubmed ID: 25904378 Relapsed Refractory BRAF-Negative, IGHV4-34-Positive Variant of Hairy Cell Leukemia: A Distinct Entity? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2016 | Pubmed ID: 24982452 DNMT3A, TET2, and JAK2 Mutations in Polycythemia Vera Following Long-term Remission of Secondary Acute Myeloid Leukemia Leukemia & Lymphoma. Dec, 2015 | Pubmed ID: 26700872 Combination of Hyper-CVAD with Ponatinib As First-line Therapy for Patients with Philadelphia Chromosome-positive Acute Lymphoblastic Leukaemia: a Single-centre, Phase 2 Study The Lancet. Oncology. Nov, 2015 | Pubmed ID: 26432046 Acute Myeloid Leukemia with MYC Rearrangement and JAK2 V617F Mutation Cancer Genetics. Nov, 2015 | Pubmed ID: 26382622 Long-term Follow-up of a Phase 2 Study of Chemotherapy Plus Dasatinib for the Initial Treatment of Patients with Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Cancer. Dec, 2015 | Pubmed ID: 26308885 Epstein-Barr Virus MicroRNAs Are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival EBioMedicine. Jun, 2015 | Pubmed ID: 26288818 Fludarabine, Cyclophosphamide, and Multiple-dose Rituximab As Frontline Therapy for Chronic Lymphocytic Leukemia Cancer. Nov, 2015 | Pubmed ID: 26218678 Complex Karyotype is a Stronger Predictor Than Del(17p) for an Inferior Outcome in Relapsed or Refractory Chronic Lymphocytic Leukemia Patients Treated with Ibrutinib-based Regimens Cancer. Oct, 2015 | Pubmed ID: 26193999 Association of Lymphoid Malignancies and Philadelphia-chromosome Negative Myeloproliferative Neoplasms: Clinical Characteristics, Therapy and Outcome Leukemia Research. Aug, 2015 | Pubmed ID: 26012362 Disseminated Histoplasmosis As Pseudo Richter's Transformation in a Patient with Chronic Lymphocytic Leukemia American Journal of Hematology. Aug, 2015 | Pubmed ID: 25850565 Outcomes of Patients With Chronic Lymphocytic Leukemia and Richter's Transformation After Transplantation Failure Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2015 | Pubmed ID: 25847930 Meir Wetzler, MD Cancer. Jul, 2015 | Pubmed ID: 25832851 The Addition of CD20 Monoclonal Antibodies to Lenalidomide Improves Response Rates and Survival in Relapsed/refractory Patients with Chronic Lymphocytic Leukaemia Relative to Lenalidomide Monotherapy - the MD Anderson Cancer Center Experience British Journal of Haematology. Mar, 2015 | Pubmed ID: 25824652 Durable Remission with Rituximab in a Patient with an Unusual Variant of Castleman's Disease with Myelofibrosis-TAFRO Syndrome American Journal of Hematology. Nov, 2015 | Pubmed ID: 25808231 Aberrant LPL Expression, Driven by STAT3, Mediates Free Fatty Acid Metabolism in CLL Cells Molecular Cancer Research : MCR. May, 2015 | Pubmed ID: 25733697 High Fluorescence in Situ Hybridization Percentage of Deletion 11q in Patients with Chronic Lymphocytic Leukemia is an Independent Predictor of Adverse Outcome American Journal of Hematology. Jun, 2015 | Pubmed ID: 25683856 Outcomes of Patients with Chronic Lymphocytic Leukemia After Discontinuing Ibrutinib Blood. Mar, 2015 | Pubmed ID: 25573991 Phase I/II Trial of the Combination of Midostaurin (PKC412) and 5-azacytidine for Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome American Journal of Hematology. Apr, 2015 | Pubmed ID: 25530214 Very High Levels of Lactate Dehydrogenase at Diagnosis Predict Central Nervous System Relapse in Acute Promyelocytic Leukaemia British Journal of Haematology. May, 2015 | Pubmed ID: 25413673 Phase II Study of Methotrexate, Vincristine, Pegylated-asparaginase, and Dexamethasone (MOpAD) in Patients with Relapsed/refractory Acute Lymphoblastic Leukemia American Journal of Hematology. Feb, 2015 | Pubmed ID: 25368968 Second Cancers in Patients with Chronic Lymphocytic Leukemia Who Received Frontline Fludarabine, Cyclophosphamide and Rituximab Therapy: Distribution and Clinical Outcomes Leukemia & Lymphoma. Jun, 2015 | Pubmed ID: 25308294 Incidence of and Risk Factors for Involvement of the Central Nervous System in Acute Myeloid Leukemia Leukemia & Lymphoma. May, 2015 | Pubmed ID: 25110819 Myeloid Neoplasms After Breast Cancer: "therapy-related" Not an Independent Poor Prognostic Factor Leukemia & Lymphoma. Apr, 2015 | Pubmed ID: 25048874 Requirement for Ssbp2 in Hematopoietic Stem Cell Maintenance and Stress Response Journal of Immunology (Baltimore, Md. : 1950). Nov, 2014 | Pubmed ID: 25238756 Clinical Significance of Microcytosis in Patients with Primary Myelofibrosis Leukemia Research. Oct, 2014 | Pubmed ID: 25217891 Isolated Mesenteric CD20-positive Myeloid Sarcoma Clinical Lymphoma, Myeloma & Leukemia. Dec, 2014 | Pubmed ID: 25131853 FCR and Bevacizumab Treatment in Patients with Relapsed Chronic Lymphocytic Leukemia Cancer. Nov, 2014 | Pubmed ID: 25043749 A Prognostic Model of Therapy-related Myelodysplastic Syndrome for Predicting Survival and Transformation to Acute Myeloid Leukemia Clinical Lymphoma, Myeloma & Leukemia. Oct, 2014 | Pubmed ID: 24875590 STAT3-activated GM-CSFRα Translocates to the Nucleus and Protects CLL Cells from Apoptosis Molecular Cancer Research : MCR. Sep, 2014 | Pubmed ID: 24836891 Stimulation of the B-cell Receptor Activates the JAK2/STAT3 Signaling Pathway in Chronic Lymphocytic Leukemia Cells Blood. Jun, 2014 | Pubmed ID: 24778152 Treatment with FLT3 Inhibitor in Patients with FLT3-mutated Acute Myeloid Leukemia is Associated with Development of Secondary FLT3-tyrosine Kinase Domain Mutations Cancer. Jul, 2014 | Pubmed ID: 24737502 Eradication of Bone Marrow Minimal Residual Disease May Prompt Early Treatment Discontinuation in CLL Blood. Jun, 2014 | Pubmed ID: 24705492 Interleukin-7 Receptor-α Gene Mutations Are Not Detected in Adult T-cell Acute Lymphoblastic Leukemia Cancer Medicine. Jun, 2014 | Pubmed ID: 24678068 Correlation Between FDG/PET, Histology, Characteristics, and Survival in 332 Patients with Chronic Lymphoid Leukemia Blood. May, 2014 | Pubmed ID: 24615780 Statin and Aspirin Use is Associated with Improved Outcome of FCR Therapy in Relapsed/refractory Chronic Lymphocytic Leukemia Blood. Feb, 2014 | Pubmed ID: 24578497 Interaction Between Myelomonocytic and Lymphoid Cells in a Patient with Acute Myelomonocytic Leukemia and Chronic Lymphocytic Leukemia Leukemia & Lymphoma. Jun, 2014 | Pubmed ID: 23987820 Personalized Medicine in CLL: Current Status and Future Perspectives Cancer Letters. Sep, 2014 | Pubmed ID: 23879961 Atypical Chronic Lymphocytic Leukemia with Polyglandular Autoimmune Endocrinopathy Type II: a Complex Profile Leukemia & Lymphoma. Apr, 2014 | Pubmed ID: 23829280 The PI3-kinase Delta Inhibitor Idelalisib (GS-1101) Targets Integrin-mediated Adhesion of Chronic Lymphocytic Leukemia (CLL) Cell to Endothelial and Marrow Stromal Cells PloS One. 2013 | Pubmed ID: 24376763 Detection of Dormant Chronic Myeloid Leukemia Clones in the Bone Marrow of Patients in Complete Molecular Remission Clinical Lymphoma, Myeloma & Leukemia. Dec, 2013 | Pubmed ID: 24060288 Targeting Inflammatory Pathways in Chronic Lymphocytic Leukemia Critical Reviews in Oncology/hematology. Dec, 2013 | Pubmed ID: 23941728 Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia PloS One. 2013 | Pubmed ID: 23936456 Clofarabine, Idarubicin, and Cytarabine (CIA) As Frontline Therapy for Patients ≤60 Years with Newly Diagnosed Acute Myeloid Leukemia American Journal of Hematology. Nov, 2013 | Pubmed ID: 23877926 Detection of MRD May Predict the Outcome of Patients with Philadelphia Chromosome-positive ALL Treated with Tyrosine Kinase Inhibitors Plus Chemotherapy Blood. Aug, 2013 | Pubmed ID: 23836561 Prognostic Value of MiR-155 in Individuals with Monoclonal B-cell Lymphocytosis and Patients with B Chronic Lymphocytic Leukemia Blood. Sep, 2013 | Pubmed ID: 23821659 CD4(-)/CD8(-) Variant of T-cell Large Granular Lymphocytic Leukemia or Hepatosplenic T-cell Lymphoma: a Clinicopathologic Dilemma Clinical Lymphoma, Myeloma & Leukemia. Oct, 2013 | Pubmed ID: 23800602 Molecular Analysis of Patients with Polycythemia Vera or Essential Thrombocythemia Receiving Pegylated Interferon α-2a Blood. Aug, 2013 | Pubmed ID: 23782935 Acquisition of Cytogenetic Abnormalities in Patients with IPSS Defined Lower-risk Myelodysplastic Syndrome is Associated with Poor Prognosis and Transformation to Acute Myelogenous Leukemia American Journal of Hematology. Oct, 2013 | Pubmed ID: 23760779 Signal Transducer and Activator of Transcription-3 Induces MicroRNA-155 Expression in Chronic Lymphocytic Leukemia PloS One. 2013 | Pubmed ID: 23750211 Randomized Open-label Phase II Study of Decitabine in Patients with Low- or Intermediate-risk Myelodysplastic Syndromes Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2013 | Pubmed ID: 23733767 Signal Transducer and Activator of Transcription (STAT)-3 Regulates MicroRNA Gene Expression in Chronic Lymphocytic Leukemia Cells Molecular Cancer. 2013 | Pubmed ID: 23725032 Salvage Therapy Using FLT3 Inhibitors May Improve Long-term Outcome of Relapsed or Refractory AML in Patients with FLT3-ITD British Journal of Haematology. Jun, 2013 | Pubmed ID: 23530930 Prognostic Impact of RAS Mutations in Patients with Myelodysplastic Syndrome American Journal of Hematology. May, 2013 | Pubmed ID: 23512829 Spontaneous Remission of Chemo-immunotherapy Related, Non-transplant Epstein-Barr Virus-associated Lymphoproliferative Disorder in a Patient with Chronic Lymphocytic Leukemia Leukemia & Lymphoma. Nov, 2013 | Pubmed ID: 23387894 Prognostic Implications and Clinical Characteristics Associated with Bone Marrow Fibrosis in Patients with Myelofibrosis Leukemia & Lymphoma. Nov, 2013 | Pubmed ID: 23343175 Chronic Lymphocytic Leukemia with Central Nervous System Involvement: a High-risk Disease? Clinical Lymphoma, Myeloma & Leukemia. Jun, 2013 | Pubmed ID: 23332395 Central Nervous System Richter's Transformation and Parvovirus B19 Infection Leukemia & Lymphoma. Sep, 2013 | Pubmed ID: 23320889 Is Acute Myeloid Leukemia a Liquid Tumor? International Journal of Cancer. Aug, 2013 | Pubmed ID: 23280377 The Significance of Spliceosome Mutations in Chronic Lymphocytic Leukemia Leukemia & Lymphoma. Jul, 2013 | Pubmed ID: 23270583 Azacitidine in Fludarabine-refractory Chronic Lymphocytic Leukemia: a Phase II Study Clinical Lymphoma, Myeloma & Leukemia. Jun, 2013 | Pubmed ID: 23265768 Epstein-Barr Virus-induced CD30-positive Diffuse Large B-cell Lymphoma in a Patient with Mixed-phenotypic Leukemia Treated with Clofarabine Clinical Lymphoma, Myeloma & Leukemia. Jun, 2013 | Pubmed ID: 23246163 Ocular Granulocytic Sarcoma: a Case Report and Literature Review of Ocular Extramedullary Acute Myeloid Leukemia Clinical Lymphoma, Myeloma & Leukemia. Feb, 2013 | Pubmed ID: 23017332 Deletion of TAK1 in the Myeloid Lineage Results in the Spontaneous Development of Myelomonocytic Leukemia in Mice PloS One. 2012 | Pubmed ID: 23251462 Therapeutic Effects of Ruxolitinib in Patients with Myelofibrosis Without Clinically Significant Splenomegaly Blood. Sep, 2012 | Pubmed ID: 23019204 Heterodimeric JAK-STAT Activation As a Mechanism of Persistence to JAK2 Inhibitor Therapy Nature. Sep, 2012 | Pubmed ID: 22820254 Long-term Outcomes of 107 Patients with Myelofibrosis Receiving JAK1/JAK2 Inhibitor Ruxolitinib: Survival Advantage in Comparison to Matched Historical Controls Blood. Aug, 2012 | Pubmed ID: 22718840 A Phase II Study of Lenalidomide Alone in Relapsed/refractory Acute Myeloid Leukemia or High-risk Myelodysplastic Syndromes with Chromosome 5 Abnormalities Clinical Lymphoma, Myeloma & Leukemia. Oct, 2012 | Pubmed ID: 22579233 Phase I-II Study of Bendamustine in Patients with Acute Leukemia and High Risk Myelodysplastic Syndrome Clinical Lymphoma, Myeloma & Leukemia. Jun, 2012 | Pubmed ID: 22578814 Therapy with the Histone Deacetylase Inhibitor Pracinostat for Patients with Myelofibrosis Leukemia Research. Sep, 2012 | Pubmed ID: 22475363 Phase 2 Study of the JAK Kinase Inhibitor Ruxolitinib in Patients with Refractory Leukemias, Including Postmyeloproliferative Neoplasm Acute Myeloid Leukemia Blood. May, 2012 | Pubmed ID: 22422826 Final Results of the Phase II Study of Rabbit Anti-thymocyte Globulin, Ciclosporin, Methylprednisone, and Granulocyte Colony-stimulating Factor in Patients with Aplastic Anaemia and Myelodysplastic Syndrome British Journal of Haematology. May, 2012 | Pubmed ID: 22360602 Acute Lymphoblastic Leukemia Arising in Post-polycythemic Myelofibrosis: a Rare Entity Leukemia & Lymphoma. Sep, 2012 | Pubmed ID: 22303899 Phase II Study of the Histone Deacetylase Inhibitor Panobinostat (LBH589) in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndrome American Journal of Hematology. Jan, 2012 | Pubmed ID: 22072492 A Randomized Study of 2 Dose Levels of Intravenous Clofarabine in the Treatment of Patients with Higher-risk Myelodysplastic Syndrome Cancer. Feb, 2012 | Pubmed ID: 21751197 Implications of Discrepancy in Morphologic Diagnosis of Myelodysplastic Syndrome Between Referral and Tertiary Care Centers Blood. Oct, 2011 | Pubmed ID: 21868570 Treatment with Lenalidomide Modulates T-cell Immunophenotype and Cytokine Production in Patients with Chronic Lymphocytic Leukemia Cancer. Sep, 2011 | Pubmed ID: 21858802 Frontline Chemoimmunotherapy with Fludarabine, Cyclophosphamide, Alemtuzumab, and Rituximab for High-risk Chronic Lymphocytic Leukemia Blood. Aug, 2011 | Pubmed ID: 21750315 Cross-talk Between Chronic Lymphocytic Leukemia Cells and Bone Marrow Endothelial Cells: Role of Signal Transducer and Activator of Transcription 3 Human Pathology. Dec, 2011 | Pubmed ID: 21733558 Transformation of Human Mesenchymal Cells and Skin Fibroblasts into Hematopoietic Cells PloS One. 2011 | Pubmed ID: 21731684 Persistencia De Las Anormalidades Citogenéticas En Remisión Completa Después De La Inducción En Pacientes Con Leucemia Mieloide Aguda: Significación Pronóstica Y El Papel Potencial Del Trasplante Alogénico De Células Madre Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2011 | Pubmed ID: 21555694 Bone Marrow Stroma-secreted Cytokines Protect JAK2(V617F)-mutated Cells from the Effects of a JAK2 Inhibitor Cancer Research. Jun, 2011 | Pubmed ID: 21512135 Evaluating the Serial Use of the Myelofibrosis Symptom Assessment Form for Measuring Symptomatic Improvement: Performance in 87 Myelofibrosis Patients on a JAK1 and JAK2 Inhibitor (INCB018424) Clinical Trial Cancer. Nov, 2011 | Pubmed ID: 21480207 STAT-3 Activates NF-kappaB in Chronic Lymphocytic Leukemia Cells Molecular Cancer Research : MCR. Apr, 2011 | Pubmed ID: 21364020 A Phase 1-2 Study of a Farnesyltransferase Inhibitor, Tipifarnib, Combined with Idarubicin and Cytarabine for Patients with Newly Diagnosed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome Cancer. Mar, 2011 | Pubmed ID: 20960519 Ubiquitin-proteasome System Profiling in Acute Leukemias and Its Clinical Relevance Leukemia Research. Apr, 2011 | Pubmed ID: 20951430 The Synthetic Heat Shock Protein 90 (Hsp90) Inhibitor EC141 Induces Degradation of Bcr-Abl P190 Protein and Apoptosis of Ph-positive Acute Lymphoblastic Leukemia Cells Investigational New Drugs. Dec, 2011 | Pubmed ID: 20533075 Kit Inhibitor APcK110 Extends Survival in an AML Xenograft Mouse Model Investigational New Drugs. Oct, 2011 | Pubmed ID: 20517635 Preclinical Characterization of Atiprimod, a Novel JAK2 AND JAK3 Inhibitor Investigational New Drugs. Oct, 2011 | Pubmed ID: 20372971 Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis The New England Journal of Medicine. Sep, 2010 | Pubmed ID: 20843246 Stat3 Activates the Receptor Tyrosine Kinase Like Orphan Receptor-1 Gene in Chronic Lymphocytic Leukemia Cells PloS One. 2010 | Pubmed ID: 20686606 Recurrent Expression Signatures of Cytokines and Chemokines Are Present and Are Independently Prognostic in Acute Myelogenous Leukemia and Myelodysplasia Blood. Nov, 2010 | Pubmed ID: 20679526 Survival Outcomes for Clonal Evolution in Chronic Myeloid Leukemia Patients on Second Generation Tyrosine Kinase Inhibitor Therapy Cancer. Jun, 2010 | Pubmed ID: 20499401 Genome-wide DNA Methylation Profiling of Chronic Lymphocytic Leukemia Allows Identification of Epigenetically Repressed Molecular Pathways with Clinical Impact Epigenetics. Aug, 2010 | Pubmed ID: 20484983 Homologous Recombination As a Resistance Mechanism to Replication-induced Double-strand Breaks Caused by the Antileukemia Agent CNDAC Blood. Sep, 2010 | Pubmed ID: 20479284 Oral Clofarabine in the Treatment of Patients with Higher-risk Myelodysplastic Syndrome Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2010 | Pubmed ID: 20421540 Circulating Ki-67 Index in Plasma As a Biomarker and Prognostic Indicator in Chronic Lymphocytic Leukemia Leukemia Research. Oct, 2010 | Pubmed ID: 20362333 The Leukemia Stem Cell Cancer Treatment and Research. 2010 | Pubmed ID: 20306242 Phase I/II Study of Combination Therapy with Sorafenib, Idarubicin, and Cytarabine in Younger Patients with Acute Myeloid Leukemia Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2010 | Pubmed ID: 20212254 STAT3 is Constitutively Phosphorylated on Serine 727 Residues, Binds DNA, and Activates Transcription in CLL Cells Blood. Apr, 2010 | Pubmed ID: 20154216 Phase 2 Study of CEP-701, an Orally Available JAK2 Inhibitor, in Patients with Primary or Post-polycythemia Vera/essential Thrombocythemia Myelofibrosis Blood. Feb, 2010 | Pubmed ID: 20008298 Clinical Correlation of Circulating Heat Shock Protein 70 in Acute Leukemia Leukemia Research. May, 2010 | Pubmed ID: 19800118 Circulating Ki-67 Protein in Plasma As a Biomarker and Prognostic Indicator of Acute Lymphoblastic Leukemia Leukemia Research. Feb, 2010 | Pubmed ID: 19679351 Pegylated Interferon Alfa-2a Yields High Rates of Hematologic and Molecular Response in Patients with Advanced Essential Thrombocythemia and Polycythemia Vera Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2009 | Pubmed ID: 19826111 Stem Cells and Somatic Cells: Reprogramming and Plasticity Clinical Lymphoma & Myeloma. 2009 | Pubmed ID: 19778860 Células Estromales De La Médula Diversos Protegen Las Células CLL De Apoptosis Espontánea Y Droga-inducida: Desarrollo De Un Sistema Fiable Y Reproducible Para Evaluar La Resistencia a Los Medicamentos De Adherencia Mediada Por Células Estromales Blood. Nov, 2009 | Pubmed ID: 19762485 The Use of Nilotinib or Dasatinib After Failure to 2 Prior Tyrosine Kinase Inhibitors: Long-term Follow-up Blood. Nov, 2009 | Pubmed ID: 19729517 Cytogenetic Abnormalities in Essential Thrombocythemia at Presentation and Transformation International Journal of Hematology. Nov, 2009 | Pubmed ID: 19728024 Proteasome Enzymatic Activities in Plasma As Risk Stratification of Patients with Acute Myeloid Leukemia and Advanced-stage Myelodysplastic Syndrome Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2009 | Pubmed ID: 19458051 Phase 1-2a Multicenter Dose-escalation Study of Ezatiostat Hydrochloride Liposomes for Injection (Telintra, TLK199), a Novel Glutathione Analog Prodrug in Patients with Myelodysplastic Syndrome Journal of Hematology & Oncology. 2009 | Pubmed ID: 19439093 Kit Inhibitor APcK110 Induces Apoptosis and Inhibits Proliferation of Acute Myeloid Leukemia Cells Cancer Research. May, 2009 | Pubmed ID: 19383925 Incidence of Extramedullary Disease in Patients with Acute Promyelocytic Leukemia: a Single-institution Experience International Journal of Hematology. May, 2009 | Pubmed ID: 19340529 Effective Treatment of Acute Promyelocytic Leukemia with All-trans-retinoic Acid, Arsenic Trioxide, and Gemtuzumab Ozogamicin Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2009 | Pubmed ID: 19075265 Circulating Heat Shock Protein 70 and Progression in Patients with Chronic Myeloid Leukemia Leukemia Research. Feb, 2009 | Pubmed ID: 18715642 Clofarabine Combinations As Acute Myeloid Leukemia Salvage Therapy Cancer. Oct, 2008 | Pubmed ID: 18756533 A Randomized Study of Clofarabine Versus Clofarabine Plus Low-dose Cytarabine As Front-line Therapy for Patients Aged 60 Years and Older with Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome Blood. Sep, 2008 | Pubmed ID: 18565853 Phase 1 Study of the Oral Isotype Specific Histone Deacetylase Inhibitor MGCD0103 in Leukemia Blood. Aug, 2008 | Pubmed ID: 18495956 The JAK Kinase Inhibitor CP-690,550 Suppresses the Growth of Human Polycythemia Vera Cells Carrying the JAK2V617F Mutation Cancer Science. Jun, 2008 | Pubmed ID: 18482053 Phase 1 Study of XL119, a Rebeccamycin Analog, in Patients with Refractory Hematologic Malignancies Cancer. Jul, 2008 | Pubmed ID: 18473351 Mechanisms of Antileukemic Activity of the Novel Bcl-2 Homology Domain-3 Mimetic GX15-070 (obatoclax) Cancer Research. May, 2008 | Pubmed ID: 18451169 Curcumin (diferuloylmethane) Alters the Expression Profiles of MicroRNAs in Human Pancreatic Cancer Cells Molecular Cancer Therapeutics. Mar, 2008 | Pubmed ID: 18347134 Lenalidomide Induces Complete and Partial Remissions in Patients with Relapsed and Refractory Chronic Lymphocytic Leukemia Blood. Jun, 2008 | Pubmed ID: 18334676 WP1066, a Novel JAK2 Inhibitor, Suppresses Proliferation and Induces Apoptosis in Erythroid Human Cells Carrying the JAK2 V617F Mutation Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2008 | Pubmed ID: 18245540 Mutant FLT3: a Direct Target of Sorafenib in Acute Myelogenous Leukemia Journal of the National Cancer Institute. Feb, 2008 | Pubmed ID: 18230792 Enzymatic Activity of Circulating Proteasomes Correlates with Clinical Behavior in Patients with Chronic Lymphocytic Leukemia Cancer. Mar, 2008 | Pubmed ID: 18224667 Phase I-II Study of Oxaliplatin, Fludarabine, Cytarabine, and Rituximab Combination Therapy in Patients with Richter's Syndrome or Fludarabine-refractory Chronic Lymphocytic Leukemia Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2008 | Pubmed ID: 18182662 WP1066 Disrupts Janus Kinase-2 and Induces Caspase-dependent Apoptosis in Acute Myelogenous Leukemia Cells Cancer Research. Dec, 2007 | Pubmed ID: 18056455 Safety and Clinical Activity of the Combination of 5-azacytidine, Valproic Acid, and All-trans Retinoic Acid in Acute Myeloid Leukemia and Myelodysplastic Syndrome Blood. Oct, 2007 | Pubmed ID: 17596541 Leucemia Aguda Biphenotypic: Una Serie Del Caso British Journal of Haematology. Jul, 2007 | Pubmed ID: 17593028 Activation of a Novel Bcr/Abl Destruction Pathway by WP1130 Induces Apoptosis of Chronic Myelogenous Leukemia Cells Blood. Apr, 2007 | Pubmed ID: 17202319 Blockade of Adaptive Defensive Changes in Cholesterol Uptake and Synthesis in AML by the Addition of Pravastatin to Idarubicin + High-dose Ara-C: a Phase 1 Study Blood. Apr, 2007 | Pubmed ID: 17158228 Phase I/II Study of Subcutaneous Homoharringtonine in Patients with Chronic Myeloid Leukemia Who Have Failed Prior Therapy Cancer. Jan, 2007 | Pubmed ID: 17154172 Results of a Randomized Study of 3 Schedules of Low-dose Decitabine in Higher-risk Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia Blood. Jan, 2007 | Pubmed ID: 16882708 Atiprimod Blocks Phosphorylation of JAK-STAT and Inhibits Proliferation of Acute Myeloid Leukemia (AML) Cells Leukemia Research. Jan, 2007 | Pubmed ID: 16828865 Studying the Right Cell in Acute Myelogenous Leukemia: Dynamic Changes of Apoptosis and Signal Transduction Pathway Protein Expression in Chemotherapy Resistant Ex-vivo Selected "survivor Cells" Cell Cycle (Georgetown, Tex.). Dec, 2006 | Pubmed ID: 17172852 Mechanisms of Apoptosis Sensitivity and Resistance to the BH3 Mimetic ABT-737 in Acute Myeloid Leukemia Cancer Cell. Nov, 2006 | Pubmed ID: 17097560 Phase II Study of Low-dose Interleukin-11 in Patients with Myelodysplastic Syndrome Leukemia & Lymphoma. Oct, 2006 | Pubmed ID: 17071475 Potential Role of Activated Platelets in Homing of Human Endothelial Progenitor Cells to Subendothelial Matrix Thrombosis and Haemostasis. Oct, 2006 | Pubmed ID: 17003929 Transfusion. Oct, 2006 | Pubmed ID: 17002637 Distinct Biological Impact of Dephosphorylation Vs. Downregulation of P210Bcr-Abl: Implications for Imatinib Mesylate Response and Resistance Leukemia & Lymphoma. Aug, 2006 | Pubmed ID: 16966279 Phase 1/2 Study of the Combination of 5-aza-2'-deoxycytidine with Valproic Acid in Patients with Leukemia Blood. Nov, 2006 | Pubmed ID: 16882711 Simultaneous Inhibition of PDK1/AKT and Fms-like Tyrosine Kinase 3 Signaling by a Small-molecule KP372-1 Induces Mitochondrial Dysfunction and Apoptosis in Acute Myelogenous Leukemia Cancer Research. Apr, 2006 | Pubmed ID: 16585200 Triptolide Induces Caspase-dependent Cell Death Mediated Via the Mitochondrial Pathway in Leukemic Cells Blood. Jul, 2006 | Pubmed ID: 16556893 Plasma Thrombopoietin Compared with Immunoglobulin Heavy-chain Mutation Status As a Predictor of Survival in Chronic Lymphocytic Leukemia Blood. Aug, 2006 | Pubmed ID: 16551975 Eradication of Leukemia Stem Cells As a New Goal of Therapy in Leukemia Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2006 | Pubmed ID: 16428470 Clofarabine and Cytarabine Combination As Induction Therapy for Acute Myeloid Leukemia (AML) in Patients 50 Years of Age or Older Blood. Jul, 2006 | Pubmed ID: 16403905 The Anti-angiogenesis Agent, AG-013736, Has Minimal Activity in Elderly Patients with Poor Prognosis Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) Leukemia Research. Jul, 2006 | Pubmed ID: 16332390 Pharmacodynamics of Cytarabine Alone and in Combination with 7-hydroxystaurosporine (UCN-01) in AML Blasts in Vitro and During a Clinical Trial Blood. Mar, 2006 | Pubmed ID: 16293603 Adaphostin-induced Oxidative Stress Overcomes BCR/ABL Mutation-dependent and -independent Imatinib Resistance Blood. Mar, 2006 | Pubmed ID: 16291594 Z-138 Cell Line Was Derived from a Patient with Blastoid Variant Mantle Cell Lymphoma Leukemia Research. Apr, 2006 | Pubmed ID: 16203034 OSW-1: a Natural Compound with Potent Anticancer Activity and a Novel Mechanism of Action Journal of the National Cancer Institute. Dec, 2005 | Pubmed ID: 16333034 WP-1034, a Novel JAK-STAT Inhibitor, with Proapoptotic and Antileukemic Activity in Acute Myeloid Leukemia (AML) Anticancer Research. May-Jun, 2005 | Pubmed ID: 16158916 Circulating Endothelial Progenitor Cells and Coronary Collaterals in Patients with Non-ST Segment Elevation Myocardial Infarction Journal of Vascular Research. Sep-Oct, 2005 | Pubmed ID: 16088214 AMN107, a Novel Aminopyrimidine Inhibitor of P190 Bcr-Abl Activation and of in Vitro Proliferation of Philadelphia-positive Acute Lymphoblastic Leukemia Cells Cancer. Sep, 2005 | Pubmed ID: 16078266 A Novel Ring-substituted Diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) Methane, Inhibits Extracellular Signal-regulated Kinase Activation and Induces Apoptosis in Acute Myelogenous Leukemia Cancer Research. Apr, 2005 | Pubmed ID: 15805291 Metastasis--an Alternative Hypothesis Cancer. Apr, 2005 | Pubmed ID: 15739196 Complex Biallelic IGH Rearrangements in IgM-expressing Z-138 Cell Line: Involvement of Downstream Immunoglobulin Class Switch Recombination Genes, Chromosomes & Cancer. Feb, 2005 | Pubmed ID: 15543623 Results of a Phase 1-2 Study of Clofarabine in Combination with Cytarabine (ara-C) in Relapsed and Refractory Acute Leukemias Blood. Feb, 2005 | Pubmed ID: 15486072 Aberrant Morphology, Proliferation, and Apoptosis of B-cell Chronic Lymphocytic Leukemia Cells Hematology (Amsterdam, Netherlands). Aug, 2004 | Pubmed ID: 15621735 Both Cell Fusion and Transdifferentiation Account for the Transformation of Human Peripheral Blood CD34-positive Cells into Cardiomyocytes in Vivo Circulation. Dec, 2004 | Pubmed ID: 15596566 The Synthetic Triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic Acid Induces Caspase-dependent and -independent Apoptosis in Acute Myelogenous Leukemia Cancer Research. Nov, 2004 | Pubmed ID: 15520199 Arsenic Derivatives As Therapeutic Agents for Hematologic Malignancies Leukemia Research. Sep, 2004 | Pubmed ID: 15234564 Nuclear Factor-kappaB and STAT3 Are Constitutively Active in CD138+ Cells Derived from Multiple Myeloma Patients, and Suppression of These Transcription Factors Leads to Apoptosis Blood. Apr, 2004 | Pubmed ID: 15070700 Hematopoietic Recovery Following Induction Therapy of Acute Leukemias: Prognostic Implications and a New Look at the Definition of Remission Leukemia & Lymphoma. Jan, 2004 | Pubmed ID: 15061199 Expression of Constitutively Active Nuclear-kappa B RelA Transcription Factor in Blasts of Acute Myeloid Leukemia Human Pathology. Feb, 2004 | Pubmed ID: 14991544 Transdifferentiation of Human Peripheral Blood CD34+-enriched Cell Population into Cardiomyocytes, Endothelial Cells, and Smooth Muscle Cells in Vivo Circulation. Oct, 2003 | Pubmed ID: 14568894 Impact of P210(Bcr-Abl) on Ultraviolet C Wavelength-induced DNA Damage and Repair Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2003 | Pubmed ID: 14506164 Adult Stem Cells for Tissue Repair - a New Therapeutic Concept? The New England Journal of Medicine. Aug, 2003 | Pubmed ID: 12904523 Inhibition of Acute Lymphoblastic and Myeloid Leukemias by a Novel Kinase Inhibitor Blood. Dec, 2003 | Pubmed ID: 12881315 Increased Apoptosis in Bone Marrow B Lymphocytes but Not T Lymphocytes in Myelodysplastic Syndrome Blood. Sep, 2003 | Pubmed ID: 12730116 Resveratrol Blocks Interleukin-1beta-induced Activation of the Nuclear Transcription Factor NF-kappaB, Inhibits Proliferation, Causes S-phase Arrest, and Induces Apoptosis of Acute Myeloid Leukemia Cells Blood. Aug, 2003 | Pubmed ID: 12689943 Granulocyte-macrophage Colony-stimulating Factor (GM-CSF) Induces Antiapoptotic and Proapoptotic Signals in Acute Myeloid Leukemia Blood. Jul, 2003 | Pubmed ID: 12663443 Commentary: Effect of Flavonoids on Normal and Leukemic Cells Leukemia Research. Jun, 2003 | Pubmed ID: 12648504 Modulation of Cellular Signaling Pathways: Prospects for Targeted Therapy in Hematological Malignancies Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2003 | Pubmed ID: 12576416 N-(4-Hydroxylphenyl)retinamide (fenretinide, 4-HPR), a Retinoid Compound with Antileukemic and Proapoptotic Activity in Acute Lymphoblastic Leukemia (ALL) Leukemia Research. Mar, 2003 | Pubmed ID: 12537979 Pilot Study of Pegylated Interferon-alpha 2b in Patients with Essential Thrombocythemia Cancer Chemotherapy and Pharmacology. Jan, 2003 | Pubmed ID: 12497210 The Clinical Significance of Tumor Necrosis Factor-alpha Plasma Level in Patients Having Chronic Lymphocytic Leukemia Blood. Aug, 2002 | Pubmed ID: 12149200 Reduced Focal Adhesion Kinase and Paxillin Phosphorylation in BCR-ABL-transfected Cells Cancer. Jul, 2002 | Pubmed ID: 12124845 Time to Platelet Recovery Predicts Outcome of Patients with De Novo Acute Lymphoblastic Leukaemia Who Have Achieved a Complete Remission British Journal of Haematology. Jun, 2002 | Pubmed ID: 12060122 CD56 Expression Predicts Occurrence of CNS Disease in Acute Lymphoblastic Leukemia Leukemia Research. Jul, 2002 | Pubmed ID: 12008081 Proliferation and Apoptosis in Acute and Chronic Leukemias and Myelodysplastic Syndrome Leukemia Research. Jun, 2002 | Pubmed ID: 12007503 Synergistic Induction of Apoptosis by Simultaneous Disruption of the Bcl-2 and MEK/MAPK Pathways in Acute Myelogenous Leukemia Blood. May, 2002 | Pubmed ID: 11964319 Ex Vivo Expansion of Apheresis-derived Peripheral Blood Hematopoietic Progenitors Journal of Clinical Apheresis. 2002 | Pubmed ID: 11948700 Hepatocitos Y Las Células Epiteliales De Origen Del Donante En Los Receptores De Las Células Madre De Sangre Periférica The New England Journal of Medicine. Mar, 2002 | Pubmed ID: 11882729 Cellular Signalling Pathways: New Targets in Leukaemia Therapy British Journal of Haematology. Jan, 2002 | Pubmed ID: 11841398 Novel Triterpenoid CDDO-Me is a Potent Inducer of Apoptosis and Differentiation in Acute Myelogenous Leukemia Blood. Jan, 2002 | Pubmed ID: 11756188 Shift of Immunoglobulin Phenotypes in B-cell Precursor Cell Lines Leukemia Research. Jan, 2002 | Pubmed ID: 11734298 Descripción de una regulación dependiente de factor de transcripción del transcriptoma MicroARN Uri Rozovski1, Inbal Hazan-Halevy2, George Calin3, David Harris4, Ping Li4, Zhiming Liu4, Michael J. Keating4, Zeev Estrov4 1Division of Hematology, Davidoff Cancer Center, Rabin Medical Center, 2The Center of Nanoscience and Nanotechnology, Tel Aviv University, 3Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 4Department of Leukemia, The University of Texas MD Anderson Cancer Center Bioengineering
Descripción de una regulación dependiente de factor de transcripción del transcriptoma MicroARN Uri Rozovski1, Inbal Hazan-Halevy2, George Calin3, David Harris4, Ping Li4, Zhiming Liu4, Michael J. Keating4, Zeev Estrov4 1Division of Hematology, Davidoff Cancer Center, Rabin Medical Center, 2The Center of Nanoscience and Nanotechnology, Tel Aviv University, 3Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 4Department of Leukemia, The University of Texas MD Anderson Cancer Center Bioengineering
