Publications

• Peptide Targeted Tripod Macrocyclic Gd(III) Chelates for Cancer Molecular MRI
  Biomaterials. Oct, 2013  |   Pubmed ID: 23863450
• Design and Evaluation of New PH-sensitive Amphiphilic Cationic Lipids for SiRNA Delivery
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2013  |   Pubmed ID: 23796431
• Molecular Magnetic Resonance Imaging of Tumors with a PTPµ Targeted Contrast Agent
  Translational Oncology. Jun, 2013  |   Pubmed ID: 23730413
• Synthesis and Evaluation of a Polydisulfide with Gd-DOTA Monoamide Side Chains As a Biodegradable Macromolecular Contrast Agent for MR Blood Pool Imaging
  Contrast Media & Molecular Imaging. May-Jun, 2013  |   Pubmed ID: 23606425
• Synthesis and Evaluation of a Targeted Nanoglobular Dual-Modal Imaging Agent for MR Imaging and Image-Guided Surgery of Prostate Cancer
  Pharmaceutical Research. Mar, 2013  |   Pubmed ID: 23471641
• Molecular MRI of Liver Fibrosis by a Peptide-targeted Contrast Agent in an Experimental Mouse Model
  Investigative Radiology. Jan, 2013  |   Pubmed ID: 23192162
• Gadolinium-based Contrast Agents for Magnetic Resonance Cancer Imaging
  Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Jan-Feb, 2013  |   Pubmed ID: 23047730
• Single Cell Molecular Recognition of Migrating and Invading Tumor Cells Using a Targeted Fluorescent Probe to Receptor PTPmu
  International Journal of Cancer. Journal International Du Cancer. Apr, 2013  |   Pubmed ID: 22987116
• Albumin Pre-coating Enhances Intracellular SiRNA Delivery of Multifunctional Amphiphile/siRNA Nanoparticles
  International Journal of Nanomedicine. 2012  |   Pubmed ID: 23055731
• Synthesis and Evaluation of a Peptide Targeted Small Molecular Gd-DOTA Monoamide Conjugate for MR Molecular Imaging of Prostate Cancer
  Bioconjugate Chemistry. Aug, 2012  |   Pubmed ID: 22812444
• MR Molecular Imaging of Prostate Cancer with a Peptide-targeted Contrast Agent in a Mouse Orthotopic Prostate Cancer Model
  Pharmaceutical Research. Apr, 2012  |   Pubmed ID: 22139536
• Polydisulfide Manganese(II) Complexes As Non-gadolinium Biodegradable Macromolecular MRI Contrast Agents
  Journal of Magnetic Resonance Imaging : JMRI. Mar, 2012  |   Pubmed ID: 22031457
• Ocular Pharmacokinetic Study Using T₁ Mapping and Gd-chelate- Labeled Polymers
  Pharmaceutical Research. Dec, 2011  |   Pubmed ID: 21691891
• Integrin Targeted MR Imaging
  Theranostics. 2011  |   Pubmed ID: 21547154
• Synthesis and Evaluation of Nanoglobular Macrocyclic Mn(II) Chelate Conjugates As Non-gadolinium(III) MRI Contrast Agents
  Bioconjugate Chemistry. May, 2011  |   Pubmed ID: 21473650
• Polydisulfide Based Biodegradable Macromolecular Magnetic Resonance Imaging Contrast Agents
  Israel Journal of Chemistry. Aug, 2010  |   Pubmed ID: 21331318
• Synthesis and Evaluation of Nanoglobule-cystamine-(Gd-DO3A), a Biodegradable Nanosized Magnetic Resonance Contrast Agent for Dynamic Contrast-enhanced Magnetic Resonance Urography
  International Journal of Nanomedicine. 2010  |   Pubmed ID: 20957222
• New Amphiphilic Carriers Forming PH-sensitive Nanoparticles for Nucleic Acid Delivery
  Langmuir : the ACS Journal of Surfaces and Colloids. Sep, 2010  |   Pubmed ID: 20672851
• [Findings of Electric Bronchoscopy in 67 Children with Recurrent Wheezing]
  Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics. Jun, 2010  |   Pubmed ID: 20540854
• An Effective Targeted Nanoglobular Manganese(II) Chelate Conjugate for Magnetic Resonance Molecular Imaging of Tumor Extracellular Matrix
  Molecular Pharmaceutics. Aug, 2010  |   Pubmed ID: 20481565
• Stability and Biodistribution of a Biodegradable Macromolecular MRI Contrast Agent Gd-DTPA Cystamine Copolymers (GDCC) in Rats
  Pharmaceutical Research. Jul, 2010  |   Pubmed ID: 20393871
• Peptide-targeted Nanoglobular Gd-DOTA Monoamide Conjugates for Magnetic Resonance Cancer Molecular Imaging
  Biomacromolecules. Mar, 2010  |   Pubmed ID: 20131758
• Molecular Imaging of HPMA Copolymers: Visualizing Drug Delivery in Cell, Mouse and Man
  Advanced Drug Delivery Reviews. Feb, 2010  |   Pubmed ID: 20060431
• Noninvasive Evaluation of Antiangiogenic Effect in a Mouse Tumor Model by DCE-MRI with Gd-DTPA Cystamine Copolymers
  Molecular Pharmaceutics. Feb, 2010  |   Pubmed ID: 19958031
• Rapid Simultaneous Acquisition of T1 and T2 Mapping Images Using Multishot Double Spin-echo EPI and Automated Variations of TR and TE (ms-DSEPI-T12)
  NMR in Biomedicine. Jan, 2010  |   Pubmed ID: 19777499
• Application of a Biodegradable Macromolecular Contrast Agent in Dynamic Contrast-enhanced MRI for Assessing the Efficacy of Indocyanine Green-enhanced Photothermal Cancer Therapy
  Journal of Magnetic Resonance Imaging : JMRI. Aug, 2009  |   Pubmed ID: 19629979
• Tumor Characterization with Dynamic Contrast Enhanced Magnetic Resonance Imaging and Biodegradable Macromolecular Contrast Agents in Mice
  Pharmaceutical Research. Sep, 2009  |   Pubmed ID: 19597972
• Targeted Intracellular Codelivery of Chemotherapeutics and Nucleic Acid with a Well-defined Dendrimer-based Nanoglobular Carrier
  Biomaterials. Oct, 2009  |   Pubmed ID: 19595449
• Targeted Systemic Delivery of a Therapeutic SiRNA with a Multifunctional Carrier Controls Tumor Proliferation in Mice
  Molecular Pharmaceutics. May-Jun, 2009  |   Pubmed ID: 19296675
• A Peptide-targeted Delivery System with PH-sensitive Amphiphilic Cell Membrane Disruption for Efficient Receptor-mediated SiRNA Delivery
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2009  |   Pubmed ID: 19135104
• Structural Effect on Degradability and in Vivo Contrast Enhancement of Polydisulfide Gd(III) Complexes As Biodegradable Macromolecular MRI Contrast Agents
  Magnetic Resonance Imaging. May, 2009  |   Pubmed ID: 18814987
• A Peptide Targeted Contrast Agent Specific to Fibrin-fibronectin Complexes for Cancer Molecular Imaging with MRI
  Bioconjugate Chemistry. Dec, 2008  |   Pubmed ID: 19053180
• Characterization of Tumor Angiogenesis with Dynamic Contrast-enhanced MRI and Biodegradable Macromolecular Contrast Agents in Mice
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2008  |   Pubmed ID: 19025902
• Synthesis and Evaluation of Globular Gd-DOTA-monoamide Conjugates with Precisely Controlled Nanosizes for Magnetic Resonance Angiography
  Biomacromolecules. Oct, 2008  |   Pubmed ID: 18771313
• Contrast-enhanced MRI-guided Photodynamic Cancer Therapy with a Pegylated Bifunctional Polymer Conjugate
  Pharmaceutical Research. Sep, 2008  |   Pubmed ID: 18584312
• Gadolinium-conjugated TiO2-DNA Oligonucleotide Nanoconjugates Show Prolonged Intracellular Retention Period and T1-weighted Contrast Enhancement in Magnetic Resonance Images
  Nanomedicine : Nanotechnology, Biology, and Medicine. Sep, 2008  |   Pubmed ID: 18567541
• A Multifunctional and Reversibly Polymerizable Carrier for Efficient SiRNA Delivery
  Biomaterials. Jan, 2008  |   Pubmed ID: 17923154
• [Determination of the Lung Function by Impulse Oscillometry in 549 Healthy Children in Chengdu Area]
  Zhonghua Er Ke Za Zhi. Chinese Journal of Pediatrics. Oct, 2007  |   Pubmed ID: 18211755
• Novel Polymerizable Surfactants with PH-sensitive Amphiphilicity and Cell Membrane Disruption for Efficient SiRNA Delivery
  Bioconjugate Chemistry. Nov-Dec, 2007  |   Pubmed ID: 17939730
• Conjugation of Poorly Absorptive Drugs with Mucoadhesive Polymers for the Improvement of Oral Absorption of Drugs
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2007  |   Pubmed ID: 17888541
• RGD Targeted Poly(L-glutamic Acid)-cystamine-(Gd-DO3A) Conjugate for Detecting Angiogenesis Biomarker Alpha(v) Beta3 Integrin with MRT, Mapping
  International Journal of Nanomedicine. 2007  |   Pubmed ID: 17722547
• In Vivo Evaluation of a PAMAM-cystamine-(Gd-DO3A) Conjugate As a Biodegradable Macromolecular MRI Contrast Agent
  Experimental Biology and Medicine (Maywood, N.J.). Sep, 2007  |   Pubmed ID: 17720954
• Synthesis, Characterization, and Gene Delivery of Poly-L-lysine Octa(3-aminopropyl)silsesquioxane Dendrimers: Nanoglobular Drug Carriers with Precisely Defined Molecular Architectures
  Molecular Pharmaceutics. Sep-Oct, 2007  |   Pubmed ID: 17705440
• Polymer Platforms for Drug Delivery and Biomedical Imaging
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2007  |   Pubmed ID: 17662500
• Modification of Gd-DTPA Cystine Copolymers with PEG-1000 Optimizes Pharmacokinetics and Tissue Retention for Magnetic Resonance Angiography
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2007  |   Pubmed ID: 17659618
• A Novel Environment-sensitive Biodegradable Polydisulfide with Protonatable Pendants for Nucleic Acid Delivery
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2007  |   Pubmed ID: 17582638
• Noninvasive Visualization of Pharmacokinetics, Biodistribution and Tumor Targeting of Poly[N-(2-hydroxypropyl)methacrylamide] in Mice Using Contrast Enhanced MRI
  Pharmaceutical Research. Jun, 2007  |   Pubmed ID: 17387601
• Application of Biomedical Imaging in Drug Discovery and Development
  Pharmaceutical Research. Jun, 2007  |   Pubmed ID: 17380256
• Gadolinium(III)-based Blood-pool Contrast Agents for Magnetic Resonance Imaging: Status and Clinical Potential
  Expert Opinion on Drug Delivery. Mar, 2007  |   Pubmed ID: 17335412
• Biodistribution and Pharmacokinetics of Colon-specific HPMA Copolymer--9-aminocamptothecin Conjugate in Mice
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2007  |   Pubmed ID: 17150276
• Polydisulfide Gd(III) Chelates As Biodegradable Macromolecular Magnetic Resonance Imaging Contrast Agents
  International Journal of Nanomedicine. 2006  |   Pubmed ID: 17722260
• Contrast-enhanced Magnetic Resonance Angiography with Biodegradable (Gd-DTPA)-cystamine Copolymers: Comparison with MS-325 in a Swine Model
  Molecular Pharmaceutics. Sep-Oct, 2006  |   Pubmed ID: 17009855
• Noninvasive Visualization of in Vivo Drug Delivery of Poly(L-glutamic Acid) Using Contrast-enhanced MRI
  Molecular Pharmaceutics. Sep-Oct, 2006  |   Pubmed ID: 17009849
• Biodegradable Cystamine Spacer Facilitates the Clearance of Gd(III) Chelates in Poly(glutamic Acid) Gd-DO3A Conjugates for Contrast-enhanced MR Imaging
  Magnetic Resonance Imaging. Sep, 2006  |   Pubmed ID: 16916710
• Contrast Enhanced MRI-guided Photodynamic Therapy for Site-specific Cancer Treatment
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Oct, 2006  |   Pubmed ID: 16902981
• Pharmacokinetics, Biodistribution and Contrast Enhanced MR Blood Pool Imaging of Gd-DTPA Cystine Copolymers and Gd-DTPA Cystine Diethyl Ester Copolymers in a Rat Model
  Pharmaceutical Research. Aug, 2006  |   Pubmed ID: 16850267
• Gd-DTPA L-cystine Bisamide Copolymers As Novel Biodegradable Macromolecular Contrast Agents for MR Blood Pool Imaging
  Pharmaceutical Research. Jun, 2006  |   Pubmed ID: 16729223
• Effect of Size and Charge on Pharmacokinetics and in Vivo MRI Contrast Enhancement of Biodegradable Polydisulfide Gd(III) Complexes
  Journal of Controlled Release : Official Journal of the Controlled Release Society. May, 2006  |   Pubmed ID: 16631270
• Colon-specific 9-aminocamptothecin-HPMA Copolymer Conjugates Containing a 1,6-elimination Spacer
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2006  |   Pubmed ID: 16290118
• PEG-g-poly(GdDTPA-co-L-cystine): Effect of PEG Chain Length on in Vivo Contrast Enhancement in MRI
  Biomacromolecules. Jul-Aug, 2005  |   Pubmed ID: 16004476
• Pharmacokinetics and Tissue Retention of (Gd-DTPA)-cystamine Copolymers, a Biodegradable Macromolecular Magnetic Resonance Imaging Contrast Agent
  Pharmaceutical Research. Apr, 2005  |   Pubmed ID: 15846467
• Contrast-enhanced MRI with New Biodegradable Macromolecular Gd(III) Complexes in Tumor-bearing Mice
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Apr, 2005  |   Pubmed ID: 15799038
• PEG-g-poly(GdDTPA-co-L-cystine): a Biodegradable Macromolecular Blood Pool Contrast Agent for MR Imaging
  Bioconjugate Chemistry. Nov-Dec, 2004  |   Pubmed ID: 15546211
• Extracellular Biodegradable Macromolecular Gadolinium(III) Complexes for MRI
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jan, 2004  |   Pubmed ID: 14705042
• Poly(l-glutamic Acid) Gd(III)-DOTA Conjugate with a Degradable Spacer for Magnetic Resonance Imaging
  Bioconjugate Chemistry. Jul-Aug, 2003  |   Pubmed ID: 12862423
• Targeted Delivery of Doxorubicin by HPMA Copolymer-hyaluronan Bioconjugates
  Pharmaceutical Research. Apr, 2002  |   Pubmed ID: 12033370
• Influence of the Structure of Drug Moieties on the in Vitro Efficacy of HPMA Copolymer-geldanamycin Derivative Conjugates
  Pharmaceutical Research. Feb, 2002  |   Pubmed ID: 11883637
• Design of Novel Bioconjugates for Targeted Drug Delivery
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2002  |   Pubmed ID: 11772458