Zhenghe Wang

Publications

• Multiproteomic and Transcriptomic Analysis of Oncogenic β-Catenin Molecular Networks
  Journal of Proteome Research. Jun, 2018  |   Pubmed ID: 29747501
• Inhibition of Intracellular Lipolysis Promotes Human Cancer Cell Adaptation to Hypoxia
  ELife. 12, 2017  |   Pubmed ID: 29256392
• Novel All-hydrocarbon Stapled P110α[E545K] Peptides As Blockers of the Oncogenic P110α[E545K]-IRS1 Interaction
  Bioorganic & Medicinal Chemistry Letters. 12, 2017  |   Pubmed ID: 29138025
• IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis
  Journal of Immunology (Baltimore, Md. : 1950). 12, 2017  |   Pubmed ID: 29070673
• Regulation of Paxillin-p130-PI3K-AKT Signaling Axis by Src and PTPRT Impacts Colon Tumorigenesis
  Oncotarget. Jul, 2017  |   Pubmed ID: 27447856
• Adverse Clinical Outcome Associated With Mutations That Typify African American Colorectal Cancers
  Journal of the National Cancer Institute. Dec, 2016  |   Pubmed ID: 27582379
• Oncogenic PIK3CA Mutations Reprogram Glutamine Metabolism in Colorectal Cancer
  Nature Communications. 06, 2016  |   Pubmed ID: 27321283
• STAT3 As a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma
  Cancer Prevention Research (Philadelphia, Pa.). Aug, 2016  |   Pubmed ID: 27267892
• Induction of KIAA1199/CEMIP is Associated with Colon Cancer Phenotype and Poor Patient Survival
  Oncotarget. Oct, 2015  |   Pubmed ID: 26437221
• How Do Oncoprotein Mutations Rewire Protein-protein Interaction Networks?
  Expert Review of Proteomics. 2015  |   Pubmed ID: 26325016
• DNMT1-associated Long Non-coding RNAs Regulate Global Gene Expression and DNA Methylation in Colon Cancer
  Human Molecular Genetics. Nov, 2015  |   Pubmed ID: 26307088
• Novel Thiourea-based Sirtuin Inhibitory Warheads
  Bioorganic & Medicinal Chemistry Letters. Aug, 2015  |   Pubmed ID: 26081291
• TISSUE REGENERATION. Inhibition of the Prostaglandin-degrading Enzyme 15-PGDH Potentiates Tissue Regeneration
  Science (New York, N.Y.). Jun, 2015  |   Pubmed ID: 26068857
• Reply to Ashktorab Et Al.: Mutational Landscape of Colon Cancers in African Americans
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015  |   Pubmed ID: 25941411
• A Protein Interaction Between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells
  Molecular Cancer Research : MCR. Jun, 2015  |   Pubmed ID: 25753001
• Novel Recurrently Mutated Genes in African American Colon Cancers
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015  |   Pubmed ID: 25583493
• Genetic Alterations of Protein Tyrosine Phosphatases in Human Cancers
  Oncogene. Jul, 2015  |   Pubmed ID: 25263441
• Cancer Driver Candidate Genes AVL9, DENND5A and NUPL1 Contribute to MDCK Cystogenesis
  Oncoscience. 2014  |   Pubmed ID: 25621300
• Discovery of Common Sequences Absent in the Human Reference Genome Using Pooled Samples from Next Generation Sequencing
  BMC Genomics. Aug, 2014  |   Pubmed ID: 25129063
• PTPRT Regulates High-fat Diet-induced Obesity and Insulin Resistance
  PloS One. 2014  |   Pubmed ID: 24949727
• Frequent Mutation of Receptor Protein Tyrosine Phosphatases Provides a Mechanism for STAT3 Hyperactivation in Head and Neck Cancer
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014  |   Pubmed ID: 24395800
• Regulation of Protein Stability of DNA Methyltransferase 1 by Post-translational Modifications
  Acta Biochimica Et Biophysica Sinica. Mar, 2014  |   Pubmed ID: 24389641
• Phase II Trial of Imatinib in AIDS-associated Kaposi's Sarcoma: AIDS Malignancy Consortium Protocol 042
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2014  |   Pubmed ID: 24378417
• CtIP is Required for DNA Damage-dependent Induction of P21
  Cell Cycle (Georgetown, Tex.). 2014  |   Pubmed ID: 24196441
• Targeting the Protein-protein Interaction Between IRS1 and Mutant P110α for Cancer Therapy
  Toxicologic Pathology. Jan, 2014  |   Pubmed ID: 24178578
• Epithelial to Mesenchymal Transition Promotes Breast Cancer Progression Via a Fibronectin-dependent STAT3 Signaling Pathway
  The Journal of Biological Chemistry. Jun, 2013  |   Pubmed ID: 23653350
• Gain of Interaction with IRS1 by P110α-helical Domain Mutants is Crucial for Their Oncogenic Functions
  Cancer Cell. May, 2013  |   Pubmed ID: 23643389
• Identification and Functional Characterization of P130Cas As a Substrate of Protein Tyrosine Phosphatase Nonreceptor 14
  Oncogene. Apr, 2013  |   Pubmed ID: 22710723
• Identifying Novel Protein Complexes in Cancer Cells Using Epitope-tagging of Endogenous Human Genes and Affinity-purification Mass Spectrometry
  Journal of Proteome Research. Dec, 2012  |   Pubmed ID: 23106643
• 福尔马林固定人类结肠肿瘤病理存档从全局突变分析。
  Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Aug, 2012  |   Pubmed ID: 22878650
• 如何做对齐程序测序数据执行与不同素质和从重复区域？
  BioData Mining. 2012  |   Pubmed ID: 22709551
• Coupling Cellular Localization and Function of Checkpoint Kinase 1 (Chk1) in Checkpoints and Cell Viability
  The Journal of Biological Chemistry. Jul, 2012  |   Pubmed ID: 22692200
• 乙酰化的 STAT3 是重要的肿瘤抑制基因启动子和抑制的白藜芦醇结果中去甲基甲基化。
  Proceedings of the National Academy of Sciences of the United States of America. May, 2012  |   Pubmed ID: 22547799
• Cross-talk Between Phospho-STAT3 and PLCγ1 Plays a Critical Role in Colorectal Tumorigenesis
  Molecular Cancer Research : MCR. Oct, 2011  |   Pubmed ID: 21840932
• A Mechanism-based Potent Sirtuin Inhibitor Containing Nε-thiocarbamoyl-lysine (TuAcK)
  Bioorganic & Medicinal Chemistry Letters. Aug, 2011  |   Pubmed ID: 21752644
• Tumour Suppressor Function of Protein Tyrosine Phosphatase Receptor-T
  Bioscience Reports. Oct, 2011  |   Pubmed ID: 21517784
• Reversible Methylation of Promoter-bound STAT3 by Histone-modifying Enzymes
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010  |   Pubmed ID: 21098664
• DNMT1 Stability is Regulated by Proteins Coordinating Deubiquitination and Acetylation-driven Ubiquitination
  Science Signaling. Nov, 2010  |   Pubmed ID: 21045206
• CHD7 Functions in the Nucleolus As a Positive Regulator of Ribosomal RNA Biogenesis
  Human Molecular Genetics. Sep, 2010  |   Pubmed ID: 20591827
• Characterization of the Adhesive Properties of the Type IIb Subfamily Receptor Protein Tyrosine Phosphatases
  Cell Communication & Adhesion. Apr, 2010  |   Pubmed ID: 20521994
• Identification and Functional Characterization of Paxillin As a Target of Protein Tyrosine Phosphatase Receptor T
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010  |   Pubmed ID: 20133777
• Cancer-derived Mutations in the Fibronectin III Repeats of PTPRT/PTPrho Inhibit Cell-cell Aggregation
  Cell Communication & Adhesion. Dec, 2009  |   Pubmed ID: 20230342
• MicroRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells
  Cancer Research. Oct, 2009  |   Pubmed ID: 19826040
• Epitope Tagging of Endogenous Proteins for Genome-wide Chromatin Immunoprecipitation Analysis
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19588087
• Genomic Distribution of CHD7 on Chromatin Tracks H3K4 Methylation Patterns
  Genome Research. Apr, 2009  |   Pubmed ID: 19251738
• Ugene, a Newly Identified Protein That is Commonly Overexpressed in Cancer and Binds Uracil DNA Glycosylase
  Cancer Research. Aug, 2008  |   Pubmed ID: 18676834
• Tumor-derived Extracellular Mutations of PTPRT /PTPrho Are Defective in Cell Adhesion
  Molecular Cancer Research : MCR. Jul, 2008  |   Pubmed ID: 18644975
• Differential Binding Modes of the Bromodomains of CREB-binding Protein (CBP) and P300 with Acetylated MyoD
  Biochemical and Biophysical Research Communications. Apr, 2008  |   Pubmed ID: 18222173
• Epitope Tagging of Endogenous Proteins for Genome-wide ChIP-chip Studies
  Nature Methods. Feb, 2008  |   Pubmed ID: 18176569
• 作为受体蛋白酪氨酸磷酸酶 T.基材 STAT3 的鉴定
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007  |   Pubmed ID: 17360477
• High-throughput Mutational Analysis of the Human Cancer Genome
  Pharmacogenomics. Jun, 2006  |   Pubmed ID: 16753007