Zhenghe Wang Department of Genetics and Genome Sciences Case Western Reserve University Biography Publications Institution JoVE Articles Zhenghe Wang has not added a biography. If you are Zhenghe Wang and would like to personalize this page please email our Author Liaison for assistance. Publications Multiproteomic and Transcriptomic Analysis of Oncogenic β-Catenin Molecular Networks Journal of Proteome Research. Jun, 2018 | Pubmed ID: 29747501 Inhibition of Intracellular Lipolysis Promotes Human Cancer Cell Adaptation to Hypoxia ELife. 12, 2017 | Pubmed ID: 29256392 Novel All-hydrocarbon Stapled P110α[E545K] Peptides As Blockers of the Oncogenic P110α[E545K]-IRS1 Interaction Bioorganic & Medicinal Chemistry Letters. 12, 2017 | Pubmed ID: 29138025 IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis Journal of Immunology (Baltimore, Md. : 1950). 12, 2017 | Pubmed ID: 29070673 Regulation of Paxillin-p130-PI3K-AKT Signaling Axis by Src and PTPRT Impacts Colon Tumorigenesis Oncotarget. Jul, 2017 | Pubmed ID: 27447856 Adverse Clinical Outcome Associated With Mutations That Typify African American Colorectal Cancers Journal of the National Cancer Institute. Dec, 2016 | Pubmed ID: 27582379 Oncogenic PIK3CA Mutations Reprogram Glutamine Metabolism in Colorectal Cancer Nature Communications. 06, 2016 | Pubmed ID: 27321283 STAT3 As a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma Cancer Prevention Research (Philadelphia, Pa.). Aug, 2016 | Pubmed ID: 27267892 Induction of KIAA1199/CEMIP is Associated with Colon Cancer Phenotype and Poor Patient Survival Oncotarget. Oct, 2015 | Pubmed ID: 26437221 How Do Oncoprotein Mutations Rewire Protein-protein Interaction Networks? Expert Review of Proteomics. 2015 | Pubmed ID: 26325016 DNMT1-associated Long Non-coding RNAs Regulate Global Gene Expression and DNA Methylation in Colon Cancer Human Molecular Genetics. Nov, 2015 | Pubmed ID: 26307088 Novel Thiourea-based Sirtuin Inhibitory Warheads Bioorganic & Medicinal Chemistry Letters. Aug, 2015 | Pubmed ID: 26081291 TISSUE REGENERATION. Inhibition of the Prostaglandin-degrading Enzyme 15-PGDH Potentiates Tissue Regeneration Science (New York, N.Y.). Jun, 2015 | Pubmed ID: 26068857 Reply to Ashktorab Et Al.: Mutational Landscape of Colon Cancers in African Americans Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 25941411 A Protein Interaction Between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells Molecular Cancer Research : MCR. Jun, 2015 | Pubmed ID: 25753001 Novel Recurrently Mutated Genes in African American Colon Cancers Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25583493 Genetic Alterations of Protein Tyrosine Phosphatases in Human Cancers Oncogene. Jul, 2015 | Pubmed ID: 25263441 Cancer Driver Candidate Genes AVL9, DENND5A and NUPL1 Contribute to MDCK Cystogenesis Oncoscience. 2014 | Pubmed ID: 25621300 Discovery of Common Sequences Absent in the Human Reference Genome Using Pooled Samples from Next Generation Sequencing BMC Genomics. Aug, 2014 | Pubmed ID: 25129063 PTPRT Regulates High-fat Diet-induced Obesity and Insulin Resistance PloS One. 2014 | Pubmed ID: 24949727 Frequent Mutation of Receptor Protein Tyrosine Phosphatases Provides a Mechanism for STAT3 Hyperactivation in Head and Neck Cancer Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24395800 Regulation of Protein Stability of DNA Methyltransferase 1 by Post-translational Modifications Acta Biochimica Et Biophysica Sinica. Mar, 2014 | Pubmed ID: 24389641 Phase II Trial of Imatinib in AIDS-associated Kaposi's Sarcoma: AIDS Malignancy Consortium Protocol 042 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2014 | Pubmed ID: 24378417 CtIP is Required for DNA Damage-dependent Induction of P21 Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 24196441 Targeting the Protein-protein Interaction Between IRS1 and Mutant P110α for Cancer Therapy Toxicologic Pathology. Jan, 2014 | Pubmed ID: 24178578 Epithelial to Mesenchymal Transition Promotes Breast Cancer Progression Via a Fibronectin-dependent STAT3 Signaling Pathway The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23653350 Gain of Interaction with IRS1 by P110α-helical Domain Mutants is Crucial for Their Oncogenic Functions Cancer Cell. May, 2013 | Pubmed ID: 23643389 Identification and Functional Characterization of P130Cas As a Substrate of Protein Tyrosine Phosphatase Nonreceptor 14 Oncogene. Apr, 2013 | Pubmed ID: 22710723 Identifying Novel Protein Complexes in Cancer Cells Using Epitope-tagging of Endogenous Human Genes and Affinity-purification Mass Spectrometry Journal of Proteome Research. Dec, 2012 | Pubmed ID: 23106643 글로벌 Mutational의 프로 파일링 인간 결 장 암 병 리 보관에서 포 르 말린 고정 Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Aug, 2012 | Pubmed ID: 22878650 반복 영역에서 다양 한 자질을 가진 시퀀싱 데이터에서 맞춤 프로그램 수행을 하려면? BioData Mining. 2012 | Pubmed ID: 22709551 Coupling Cellular Localization and Function of Checkpoint Kinase 1 (Chk1) in Checkpoints and Cell Viability The Journal of Biological Chemistry. Jul, 2012 | Pubmed ID: 22692200 Acetylated STAT3 종양 억제기 유전자 프로모터 및 Demethylation에서 결과 레 스 베라 트롤에 의해 저해의 메 틸 화에 대 한 결정적 이다 Proceedings of the National Academy of Sciences of the United States of America. May, 2012 | Pubmed ID: 22547799 Cross-talk Between Phospho-STAT3 and PLCγ1 Plays a Critical Role in Colorectal Tumorigenesis Molecular Cancer Research : MCR. Oct, 2011 | Pubmed ID: 21840932 A Mechanism-based Potent Sirtuin Inhibitor Containing Nε-thiocarbamoyl-lysine (TuAcK) Bioorganic & Medicinal Chemistry Letters. Aug, 2011 | Pubmed ID: 21752644 Tumour Suppressor Function of Protein Tyrosine Phosphatase Receptor-T Bioscience Reports. Oct, 2011 | Pubmed ID: 21517784 Reversible Methylation of Promoter-bound STAT3 by Histone-modifying Enzymes Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21098664 DNMT1 Stability is Regulated by Proteins Coordinating Deubiquitination and Acetylation-driven Ubiquitination Science Signaling. Nov, 2010 | Pubmed ID: 21045206 CHD7 Functions in the Nucleolus As a Positive Regulator of Ribosomal RNA Biogenesis Human Molecular Genetics. Sep, 2010 | Pubmed ID: 20591827 Characterization of the Adhesive Properties of the Type IIb Subfamily Receptor Protein Tyrosine Phosphatases Cell Communication & Adhesion. Apr, 2010 | Pubmed ID: 20521994 Identification and Functional Characterization of Paxillin As a Target of Protein Tyrosine Phosphatase Receptor T Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133777 Cancer-derived Mutations in the Fibronectin III Repeats of PTPRT/PTPrho Inhibit Cell-cell Aggregation Cell Communication & Adhesion. Dec, 2009 | Pubmed ID: 20230342 MicroRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells Cancer Research. Oct, 2009 | Pubmed ID: 19826040 Epitope Tagging of Endogenous Proteins for Genome-wide Chromatin Immunoprecipitation Analysis Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19588087 Genomic Distribution of CHD7 on Chromatin Tracks H3K4 Methylation Patterns Genome Research. Apr, 2009 | Pubmed ID: 19251738 Ugene, a Newly Identified Protein That is Commonly Overexpressed in Cancer and Binds Uracil DNA Glycosylase Cancer Research. Aug, 2008 | Pubmed ID: 18676834 Tumor-derived Extracellular Mutations of PTPRT /PTPrho Are Defective in Cell Adhesion Molecular Cancer Research : MCR. Jul, 2008 | Pubmed ID: 18644975 Differential Binding Modes of the Bromodomains of CREB-binding Protein (CBP) and P300 with Acetylated MyoD Biochemical and Biophysical Research Communications. Apr, 2008 | Pubmed ID: 18222173 Epitope Tagging of Endogenous Proteins for Genome-wide ChIP-chip Studies Nature Methods. Feb, 2008 | Pubmed ID: 18176569 수용 체 단백질 티로신 인산 가수분해 효소 T.의 기판으로 Stat3의 식별 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007 | Pubmed ID: 17360477 High-throughput Mutational Analysis of the Human Cancer Genome Pharmacogenomics. Jun, 2006 | Pubmed ID: 16753007 대체 사전 mRNA 접합 교 잡 시험 현장에서 RNA를 사용 하 여 마우스 뇌 섹션에서의 정량 분석 Xuan Guo1,2, Yiqing Zhao1,3, Hieu Nguyen1, Tonghua Liu2, Zhenghe Wang1,3, Hua Lou1,3,4 1Department of Genetics and Genome Sciences, Case Western Reserve University, 2Department of Endocrinology, Dongfang Hospital of Beijing University of Chinese Medicine, 3Case Comprehensive Cancer Center, Case Western Reserve University, 4Center for RNA Science and Therapeutics, Case Western Reserve University JoVE 57889 Genetics
대체 사전 mRNA 접합 교 잡 시험 현장에서 RNA를 사용 하 여 마우스 뇌 섹션에서의 정량 분석 Xuan Guo1,2, Yiqing Zhao1,3, Hieu Nguyen1, Tonghua Liu2, Zhenghe Wang1,3, Hua Lou1,3,4 1Department of Genetics and Genome Sciences, Case Western Reserve University, 2Department of Endocrinology, Dongfang Hospital of Beijing University of Chinese Medicine, 3Case Comprehensive Cancer Center, Case Western Reserve University, 4Center for RNA Science and Therapeutics, Case Western Reserve University JoVE 57889 Genetics
