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Articles by Zidong Li in JoVE
Quantitative and Temporal Control of Oxygen Microenvironment at the Single Islet Level Joe Fu-Jiou Lo1, Yong Wang2,3, Zidong Li1, Zhengtuo Zhao1, Di Hu1, David T. Eddington3, Jose Oberholzer2,3 1Department of Mechanical Engineering, University of Michigan-Dearborn, 2Department of Surgery/Transplant, University of Illinois at Chicago, 3Department of Bioengineering, University of Illinois at Chicago Microfluidic oxygen control confers more than just convenience and speed over hypoxic chambers for biological experiments. Especially when implemented via diffusion through a membrane, microfluidic oxygen can provide simultaneous liquid and gas phase modulations at the microscale-level. This technique enables dynamic multi-parametric experiments critical for studying islet pathophysiology.