Zsolt Ruzsics Max von Pettenkofer Institute Biography Publications Institution JoVE Articles Zsolt Ruzsics has not added a biography. If you are Zsolt Ruzsics and would like to personalize this page please email our Author Liaison for assistance. Publications Nontransformed, GM-CSF-dependent Macrophage Lines Are a Unique Model to Study Tissue Macrophage Functions Proceedings of the National Academy of Sciences of the United States of America. Jun, 2013 | Pubmed ID: 23708119 Natural Killer Cells Are Required for Extramedullary Hematopoiesis Following Murine Cytomegalovirus Infection Cell Host & Microbe. May, 2013 | Pubmed ID: 23684305 The Context of Gene Expression Defines the Immunodominance Hierarchy of Cytomegalovirus Antigens Journal of Immunology (Baltimore, Md. : 1950). Apr, 2013 | Pubmed ID: 23460738 Systemic and Local Infection Routes Govern Different Cellular Dissemination Pathways During Gammaherpesvirus Infection in Vivo Journal of Virology. Apr, 2013 | Pubmed ID: 23408606 Mouse Cytomegalovirus Egress Protein PM50 Interacts with Cellular Endophilin-A2 Cellular Microbiology. Feb, 2013 | Pubmed ID: 23189961 Block of Death-receptor Apoptosis Protects Mouse Cytomegalovirus from Macrophages and is a Determinant of Virulence in Immunodeficient Hosts PLoS Pathogens. 2012 | Pubmed ID: 23271968 Characterization of Conserved Region 2-deficient Mutants of the Cytomegalovirus Egress Protein PM53 Journal of Virology. Dec, 2012 | Pubmed ID: 22993161 Real-time Transcriptional Profiling of Cellular and Viral Gene Expression During Lytic Cytomegalovirus Infection PLoS Pathogens. Sep, 2012 | Pubmed ID: 22969428 A Beta-herpesvirus with Fluorescent Capsids to Study Transport in Living Cells PloS One. 2012 | Pubmed ID: 22792376 Cytomegalovirus Replicon-based Regulation of Gene Expression in Vitro and in Vivo PLoS Pathogens. 2012 | Pubmed ID: 22685399 A Cell Free Protein Fragment Complementation Assay for Monitoring the Core Interaction of the Human Cytomegalovirus Nuclear Egress Complex Antiviral Research. Jul, 2012 | Pubmed ID: 22580129 Ultrashort and Progressive 4sU-tagging Reveals Key Characteristics of RNA Processing at Nucleotide Resolution Genome Research. Oct, 2012 | Pubmed ID: 22539649 Transcriptional Activation of the Adenoviral Genome is Mediated by Capsid Protein VI PLoS Pathogens. Feb, 2012 | Pubmed ID: 22427750 Degradation of Cellular Mir-27 by a Novel, Highly Abundant Viral Transcript is Important for Efficient Virus Replication in Vivo PLoS Pathogens. Feb, 2012 | Pubmed ID: 22346748 The Role of Cell Types in Cytomegalovirus Infection in Vivo European Journal of Cell Biology. Jan, 2012 | Pubmed ID: 21492952 Shedding Light on the Elusive Role of Endothelial Cells in Cytomegalovirus Dissemination PLoS Pathogens. Nov, 2011 | Pubmed ID: 22114552 M94 is Essential for the Secondary Envelopment of Murine Cytomegalovirus Journal of Virology. Sep, 2011 | Pubmed ID: 21715482 Stepwise Loss of Fluorescent Core Protein V from Human Adenovirus During Entry into Cells Journal of Virology. Jan, 2011 | Pubmed ID: 21047958 Cytomegalovirus MicroRNAs Facilitate Persistent Virus Infection in Salivary Glands PLoS Pathogens. 2010 | Pubmed ID: 20976200 Dominant Negative Mutants of the Murine Cytomegalovirus M53 Gene Block Nuclear Egress and Inhibit Capsid Maturation Journal of Virology. Sep, 2010 | Pubmed ID: 20610730 A Spread-deficient Cytomegalovirus for Assessment of First-target Cells in Vaccination Journal of Virology. Aug, 2010 | Pubmed ID: 20463067 Systematic Analysis of Viral and Cellular MicroRNA Targets in Cells Latently Infected with Human Gamma-herpesviruses by RISC Immunoprecipitation Assay Cell Host & Microbe. Apr, 2010 | Pubmed ID: 20413099 A Capsid-encoded PPxY-motif Facilitates Adenovirus Entry PLoS Pathogens. Mar, 2010 | Pubmed ID: 20333243 The M74 Gene Product of Murine Cytomegalovirus (MCMV) is a Functional Homolog of Human CMV GO and Determines the Entry Pathway of MCMV Journal of Virology. May, 2010 | Pubmed ID: 20181688 Dominant-negative Proteins in Herpesviruses - from Assigning Gene Function to Intracellular Immunization Viruses. Dec, 2009 | Pubmed ID: 21994555 Genetic Reconstitution of the Human Adenovirus Type 2 Temperature-sensitive 1 Mutant Defective in Endosomal Escape Virology Journal. 2009 | Pubmed ID: 19860872 Conserved Principles of Mammalian Transcriptional Regulation Revealed by RNA Half-life Nucleic Acids Research. Sep, 2009 | Pubmed ID: 19561200 Differential Susceptibility of RAE-1 Isoforms to Mouse Cytomegalovirus Journal of Virology. Aug, 2009 | Pubmed ID: 19494006 Key Role of Splenic Myeloid DCs in the IFN-alphabeta Response to Adenoviruses in Vivo PLoS Pathogens. Nov, 2008 | Pubmed ID: 19008951 High-resolution Gene Expression Profiling for Simultaneous Kinetic Parameter Analysis of RNA Synthesis and Decay RNA (New York, N.Y.). Sep, 2008 | Pubmed ID: 18658122 The Major Virus-producing Cell Type During Murine Cytomegalovirus Infection, the Hepatocyte, is Not the Source of Virus Dissemination in the Host Cell Host & Microbe. Apr, 2008 | Pubmed ID: 18407069 Dominant-negative FADD Rescues the in Vivo Fitness of a Cytomegalovirus Lacking an Antiapoptotic Viral Gene Journal of Virology. Mar, 2008 | Pubmed ID: 18094168 Engineering of Cytomegalovirus Genomes for Recombinant Live Herpesvirus Vaccines International Journal of Medical Microbiology : IJMM. Jan, 2008 | Pubmed ID: 17702650 Mouse Cytomegalovirus MicroRNAs Dominate the Cellular Small RNA Profile During Lytic Infection and Show Features of Posttranscriptional Regulation Journal of Virology. Dec, 2007 | Pubmed ID: 17942535 Targeted Deletion of Regions Rich in Immune-evasive Genes from the Cytomegalovirus Genome As a Novel Vaccine Strategy Journal of Virology. Dec, 2007 | Pubmed ID: 17913824 Natural Killer Cells Promote Early CD8 T Cell Responses Against Cytomegalovirus PLoS Pathogens. Aug, 2007 | Pubmed ID: 17722980 Random Screening for Dominant-negative Mutants of the Cytomegalovirus Nuclear Egress Protein M50 Journal of Virology. Jun, 2007 | Pubmed ID: 17376929 Common and Specific Properties of Herpesvirus UL34/UL31 Protein Family Members Revealed by Protein Complementation Assay Journal of Virology. Dec, 2006 | Pubmed ID: 17005637 Transposon-assisted Cloning and Traceless Mutagenesis of Adenoviruses: Development of a Novel Vector Based on Species D Journal of Virology. Aug, 2006 | Pubmed ID: 16873266 The Herpesviral Fc Receptor Fcr-1 Down-regulates the NKG2D Ligands MULT-1 and H60 The Journal of Experimental Medicine. Aug, 2006 | Pubmed ID: 16831899 Adenovirus Vectors Based on Human Adenovirus Type 19a Have High Potential for Human Muscle-directed Gene Therapy Human Gene Therapy. Feb, 2006 | Pubmed ID: 16454653 Functional Domains of Murine Cytomegalovirus Nuclear Egress Protein M53/p38 Journal of Virology. Jan, 2006 | Pubmed ID: 16352532 The Nucleotide Sequence and a First Generation Gene Transfer Vector of Species B Human Adenovirus Serotype 3 Virology. Dec, 2005 | Pubmed ID: 16169033 Selective Down-regulation of the NKG2D Ligand H60 by Mouse Cytomegalovirus M155 Glycoprotein Journal of Virology. Mar, 2005 | Pubmed ID: 15709011 Conditional Cytomegalovirus Replication in Vitro and in Vivo Journal of Virology. Jan, 2005 | Pubmed ID: 15596841 Comprehensive Mutational Analysis of a Herpesvirus Gene in the Viral Genome Context Reveals a Region Essential for Virus Replication Journal of Virology. Aug, 2004 | Pubmed ID: 15254174 Two Distinct Transport Motifs in the Adenovirus E3/10.4-14.5 Proteins Act in Concert to Down-modulate Apoptosis Receptors and the Epidermal Growth Factor Receptor The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 14506242 Role of Murine Cytomegalovirus US22 Gene Family Members in Replication in Macrophages Journal of Virology. May, 2003 | Pubmed ID: 12719548 Herpesvirus Genetics Has Come of Age Trends in Microbiology. Jul, 2002 | Pubmed ID: 12110210 The Novel Early Region 3 Protein E3/49K is Specifically Expressed by Adenoviruses of Subgenus D: Implications for Epidemic Keratoconjunctivitis and Adenovirus Evolution Virology. Apr, 2002 | Pubmed ID: 12036321 Metabolic Labeling of Newly Transcribed RNA for High Resolution Gene Expression Profiling of RNA Synthesis, Processing and Decay in Cell Culture Bernd Rädle*1, Andrzej J. Rutkowski*2, Zsolt Ruzsics1, Caroline C. Friedel3, Ulrich H. Koszinowski1, Lars Dölken2 1Max von Pettenkofer Institute, 2Department of Medicine, University of Cambridge, 3Institute for Informatics, Ludwig-Maximilians-University Munich JoVE 50195 Biology
Metabolic Labeling of Newly Transcribed RNA for High Resolution Gene Expression Profiling of RNA Synthesis, Processing and Decay in Cell Culture Bernd Rädle*1, Andrzej J. Rutkowski*2, Zsolt Ruzsics1, Caroline C. Friedel3, Ulrich H. Koszinowski1, Lars Dölken2 1Max von Pettenkofer Institute, 2Department of Medicine, University of Cambridge, 3Institute for Informatics, Ludwig-Maximilians-University Munich JoVE 50195 Biology