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Mechano-Node-Pore Sensing: En snabb, etikettfri plattform för encells viskoelastiska mätningar med flera parametrar

Article DOI: 10.3791/64665-v • 05:49 min • December 2nd, 2022
December 2nd, 2022 •
*1, *2, 1, 3, 1,3, 1,2
1Graduate Program in Bioengineering, University of California, Berkeley and University of California, San Francisco, 2Department of Mechanical Engineering, University of California, Berkeley, 3Department of Electrical Engineering and Computer Sciences, University of California, Berkeley
* These authors contributed equally

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Här presenteras en metod för att mekaniskt fenotypa enstaka celler med hjälp av en elektronikbaserad mikrofluidisk plattform som kallas mechano-node-pore sensing (mechano-NPS). Denna plattform upprätthåller måttlig genomströmning av 1-10 celler / s samtidigt som man mäter både de elastiska och viskösa biofysiska egenskaperna hos celler.

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Bioengineering utgåva 190
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