Sarah Shigdar

Publications

• Modelling of Mass Transport and Distribution of Aptamer in Blood-brain Barrier for Tumour Therapy and Cancer Treatment
  European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Apr, 2022  |   Pubmed ID: 35283304
• Triple-negative Breast Cancer Brain Metastasis: An Update on Druggable Targets, Current Clinical Trials, and Future Treatment Options
  Drug Discovery Today. 05, 2022  |   Pubmed ID: 35101641
• Future of PD-1/PD-L1 Axis Modulation for the Treatment of Triple-negative Breast Cancer
  Pharmacological Research. 01, 2022  |   Pubmed ID: 34861397
• Profiling Cancer Cells by Cell-SELEX: Use of Aptamers for Discovery of Actionable Biomarkers and Therapeutic Applications Thereof
  Pharmaceutics. Dec, 2021  |   Pubmed ID: 35056924
• Diagnostics and Therapeutics in Targeting HER2 Breast Cancer: A Novel Approach
  International Journal of Molecular Sciences. Jun, 2021  |   Pubmed ID: 34200484
• Aptamers: Cutting Edge of Cancer Therapies
  Molecular Therapy : the Journal of the American Society of Gene Therapy. 08, 2021  |   Pubmed ID: 34146729
• Novel Detection of Nasty Bugs, Prevention Is Better Than Cure
  International Journal of Molecular Sciences. Dec, 2020  |   Pubmed ID: 33375709
• Author Correction: Aptamer-mediated Survivin RNAi Enables 5-fluorouracil to Eliminate Colorectal Cancer Stem Cells
  Scientific Reports. Dec, 2020  |   Pubmed ID: 33311517
• Non-Invasive Delivery of Therapeutics into the Brain: The Potential of Aptamers for Targeted Delivery
  Biomedicines. May, 2020  |   Pubmed ID: 32422973
• Strategies to Bioengineer Aptamer-driven Nanovehicles As Exceptional Molecular Tools for Targeted Therapeutics: A Review
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 07, 2020  |   Pubmed ID: 32380206
• Mathematical Approaches in Estimating Aptamer-target Binding Affinity
  Analytical Biochemistry. 07, 2020  |   Pubmed ID: 32315616
• Antibodies, Nanobodies, or Aptamers-Which Is Best for Deciphering the Proteomes of Non-Model Species?
  International Journal of Molecular Sciences. Apr, 2020  |   Pubmed ID: 32260091
• Bifunctional Aptamer-Doxorubicin Conjugate Crosses the Blood-Brain Barrier and Selectively Delivers Its Payload to EpCAM-Positive Tumor Cells
  Nucleic Acid Therapeutics. 04, 2020  |   Pubmed ID: 32027209
• Anything You Can Do, I Can Do Better: Can Aptamers Replace Antibodies in Clinical Diagnostic Applications?
  Molecules (Basel, Switzerland). Nov, 2019  |   Pubmed ID: 31801185
• Aptamer-Based Diagnostics and Therapeutics
  Pharmaceuticals (Basel, Switzerland). Jan, 2019  |   Pubmed ID: 30609700
• Radiolabelled Aptamers for Theranostic Treatment of Cancer
  Pharmaceuticals (Basel, Switzerland). Dec, 2018  |   Pubmed ID: 30586898
• EpCAM Immunotherapy Versus Specific Targeted Delivery of Drugs
  Cancers. Jan, 2018  |   Pubmed ID: 29329202
• Aptamers As Potential Therapeutic Agents for Ovarian Cancer
  Biochimie. Feb, 2018  |   Pubmed ID: 29224849
• Tailored Mesoporous Silica Nanoparticles for Controlled Drug Delivery: Platform Fabrication, Targeted Delivery, and Computational Design and Analysis
  Mini Reviews in Medicinal Chemistry. 2018  |   Pubmed ID: 27145854
• Aptamers and Glioblastoma: Their Potential Use for Imaging and Therapeutic Applications
  International Journal of Molecular Sciences. Nov, 2017  |   Pubmed ID: 29189740
• Development of Cell-Specific Aptamers: Recent Advances and Insight into the Selection Procedures
  Molecules (Basel, Switzerland). Nov, 2017  |   Pubmed ID: 29186905
• Transforming Doxorubicin into a Cancer Stem Cell Killer Via EpCAM Aptamer-mediated Delivery
  Theranostics. 2017  |   Pubmed ID: 29158811
• Aptamer-mediated Survivin RNAi Enables 5-fluorouracil to Eliminate Colorectal Cancer Stem Cells
  Scientific Reports. 07, 2017  |   Pubmed ID: 28724889
• What Potential Do Aptamers Hold in Therapeutic Delivery?
  Therapeutic Delivery. 02, 2017  |   Pubmed ID: 28088878
• Development of a Bifunctional Aptamer Targeting the Transferrin Receptor and Epithelial Cell Adhesion Molecule (EpCAM) for the Treatment of Brain Cancer Metastases
  ACS Chemical Neuroscience. 04, 2017  |   Pubmed ID: 28010059
• Challenges and Opportunities for SiRNA-based Cancer Treatment
  Cancer Letters. 02, 2017  |   Pubmed ID: 27045474
• Truncation and Mutation of a Transferrin Receptor Aptamer Enhances Binding Affinity
  Nucleic Acid Therapeutics. 12, 2016  |   Pubmed ID: 27500826
• The Application of Aptamers for Immunohistochemistry
  Nucleic Acid Therapeutics. 06, 2016  |   Pubmed ID: 26862683
• Application of Aptamers in Histopathology
  Methods in Molecular Biology (Clifton, N.J.). 2016  |   Pubmed ID: 26552827
• The Control of Epidermal Growth Factor Grafted on Mesoporous Silica Nanoparticles for Targeted Delivery
  Journal of Materials Chemistry. B. Aug, 2015  |   Pubmed ID: 32262664
• EpCAM Aptamer-mediated Survivin Silencing Sensitized Cancer Stem Cells to Doxorubicin in a Breast Cancer Model
  Theranostics. 2015  |   Pubmed ID: 26681989
• Cancer Stem Cell Targeted Therapy: Progress Amid Controversies
  Oncotarget. Dec, 2015  |   Pubmed ID: 26496035
• Overcoming Acquired Drug Resistance in Colorectal Cancer Cells by Targeted Delivery of 5-FU with EGF Grafted Hollow Mesoporous Silica Nanoparticles
  Nanoscale. Sep, 2015  |   Pubmed ID: 26242620
• Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors
  Theranostics. 2015  |   Pubmed ID: 26199647
• Fabrication of High Specificity Hollow Mesoporous Silica Nanoparticles Assisted by Eudragit for Targeted Drug Delivery
  Journal of Colloid and Interface Science. May, 2015  |   Pubmed ID: 25617610
• Nucleic Acid Aptamer-guided Cancer Therapeutics and Diagnostics: the Next Generation of Cancer Medicine
  Theranostics. 2015  |   Pubmed ID: 25553096
• Improved Efficacy and Reduced Toxicity of Doxorubicin Encapsulated in Sulfatide-containing Nanoliposome in a Glioma Model
  PloS One. 2014  |   Pubmed ID: 25072631
• Epithelial Cell Adhesion Molecule Aptamer Functionalized PLGA-lecithin-curcumin-PEG Nanoparticles for Targeted Drug Delivery to Human Colorectal Adenocarcinoma Cells
  International Journal of Nanomedicine. 2014  |   Pubmed ID: 24591829
• Cancer Stem Cells: A Contentious Hypothesis Now Moving Forward
  Cancer Letters. Mar, 2014  |   Pubmed ID: 24333726
• Inflammation and Cancer Stem Cells
  Cancer Letters. Apr, 2014  |   Pubmed ID: 23941828
• Inhibition of A/Human/Hubei/3/2005 (H3N2) Influenza Virus Infection by Silver Nanoparticles in Vitro and in Vivo
  International Journal of Nanomedicine. 2013  |   Pubmed ID: 24204140
• Aptamers As Theranostic Agents: Modifications, Serum Stability and Functionalisation
  Sensors (Basel, Switzerland). Oct, 2013  |   Pubmed ID: 24152925
• The Use of Sensitive Chemical Antibodies for Diagnosis: Detection of Low Levels of EpCAM in Breast Cancer
  PloS One. 2013  |   Pubmed ID: 23460885
• RNA Aptamers Targeting Cancer Stem Cell Marker CD133
  Cancer Letters. Mar, 2013  |   Pubmed ID: 23196060
• Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer
  PloS One. 2012  |   Pubmed ID: 23145140
• Cancer Stem Cell Targeting: the Next Generation of Cancer Therapy and Molecular Imaging
  Therapeutic Delivery. Feb, 2012  |   Pubmed ID: 22834199
• Clinical Applications of Aptamers and Nucleic Acid Therapeutics in Haematological Malignancies
  British Journal of Haematology. Oct, 2011  |   Pubmed ID: 21810089
• RNA Aptamer Against a Cancer Stem Cell Marker Epithelial Cell Adhesion Molecule
  Cancer Science. May, 2011  |   Pubmed ID: 21281402
• Cytochemical Characterisation of the Leucocytes and Thrombocytes from Murray Cod (Maccullochella Peelii Peelii, Mitchell)
  Fish & Shellfish Immunology. May, 2009  |   Pubmed ID: 19332132
• Functional Interaction Between Mutations in the Granulocyte Colony-stimulating Factor Receptor in Severe Congenital Neutropenia
  British Journal of Haematology. Aug, 2008  |   Pubmed ID: 18513286