Nanion Technologies GmbH 1 article published in JoVE Bioengineering Hybrid Cell Analysis System to Assess Structural and Contractile Changes of Human iPSC-Derived Cardiomyocytes for Preclinical Cardiac Risk Evaluation Bettina Lickiss1, Matthias Gossmann1, Peter Linder1, Ulrich Thomas2, Elena Dragicevic2, Marta Lemme2, Michael George2, Niels Fertig2, Sonja Stölzle-Feix2 1innoVitro GmbH, 2Nanion Technologies GmbH The analysis of changes in contractile function and cellular integrity of human iPSC-derived cardiomyocytes is of immense importance for nonclinical drug development. A hybrid 96-well cell analysis system addresses both parameters in a real-time and physiological manner for reliable, human-relevant results, necessary for a safe transition into clinical stages.
