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In vivo Imaging and Therapeutic Treatments in an Orthotopic Mouse Model of Ovarian Cancer
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August 17, 2010
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Orthotopic animal models of ovarian cancer replicate better human disease and therefore enhance our understanding of cancer progression and tumor response to therapy. A mouse model receives an intrabursal injection of luciferase-expressing ovarian tumor cells. Treatment is administered via oral gavage. Tumor growth is monitored by in vivo imaging system.
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Cordero, A. B., Kwon, Y., Hua, X., Godwin, A. K. In vivo Imaging and Therapeutic Treatments in an Orthotopic Mouse Model of Ovarian Cancer. J. Vis. Exp. (42), e2125, doi:10.3791/2125 (2010).
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