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John LaCava

Associate Professor
John LaCava is an Associate Professor at The European Research Institute for the Biology of Ageing; he’s also Research Faculty at The Rockefeller University and a senior investigator for the NIH 's National Center for Dynamic Interactome Research. He earned a B.S. in biotechnology from UC Davis and a Ph.D. in molecular genetics from the University of Edinburgh. Dr. LaCava 's research focuses on improving methods and technology for interactome analyses and applying such tools to tackle challenges in molecular and cell biology. For this, he frequently draws upon mass spectrometry-based affinity-proteomic techniques, with special emphasis on approaches that also enable downstream structural and biochemical studies of purified macromolecular complexes. Among other research interests, Dr. LaCava’s group studies the lifecycle of human LINE-1 retrotransposons and mechanisms of human RNA processing by the exosome.

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