Fengdong Zhao Department of Orthopedics, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University Biography Publications Institution JoVE Articles Fengdong Zhao has not added a biography. If you are Fengdong Zhao and would like to personalize this page please email our Author Liaison for assistance. Publications Emergency Surgery for a Patient with a Thoracic Spinal Epidural Abscess: a Case Report and Literature Review The Journal of International Medical Research. Apr, 2023 | Pubmed ID: 37078091 Netrin-1 Mediates Nerve Innervation and Angiogenesis Leading to Discogenic Pain Journal of Orthopaedic Translation. Mar, 2023 | Pubmed ID: 36605621 Activation of Nrf2 Signaling by 4-octyl Itaconate Attenuates the Cartilaginous Endplate Degeneration by Inhibiting E3 Ubiquitin Ligase ZNF598 Osteoarthritis and Cartilage. Feb, 2023 | Pubmed ID: 36270478 Can Oblique Lateral Interbody Fusion (OLIF) Create More Lumbosacral Lordosis in Lumbar Spine Surgery Than Minimally Invasive Transforaminal Interbody Fusion (MIS-TLIF)? Frontiers in Surgery. 2022 | Pubmed ID: 36684176 Red Light-Mediated Photoredox Catalysis Triggers Nitric Oxide Release for Treatment of Induced Intervertebral Disc Degeneration ACS Nano. Dec, 2022 | Pubmed ID: 36469724 Small Preoperative Dural Sac Cross-Sectional Area and Anteriorly Placed Fusion Cages Are Risk Factors for Indirect Decompression Failure After Oblique Lateral Interbody Fusion World Neurosurgery. Nov, 2022 | Pubmed ID: 36067941 Methyl 3,4-dihydroxybenzoate Inhibits RANKL-induced Osteoclastogenesis Via Nrf2 Signaling and Suppresses LPS-induced Osteolysis and Ovariectomy-induced Osteoporosis Acta Biochimica Et Biophysica Sinica. Aug, 2022 | Pubmed ID: 35929596 Anterior Cervical Transpedicular Screw Fixation System in Subaxial Cervical Spine: A Finite Element Comparative Study Medicine. Jul, 2022 | Pubmed ID: 35866798 Sigma-1 Receptor Attenuates Osteoclastogenesis by Promoting ER-associated Degradation of SERCA2 EMBO Molecular Medicine. Jul, 2022 | Pubmed ID: 35611810 Different Responses of Cervical Intervertebral Disc Caused by Low and High Virulence Bacterial Infection: a Comparative Study in Rats Bioengineered. May, 2022 | Pubmed ID: 35587595 Urolithin A Promotes Angiogenesis and Tissue Regeneration in a Full-Thickness Cutaneous Wound Model Frontiers in Pharmacology. 2022 | Pubmed ID: 35359856 [Establishment of Finite Element Model of Anterior Cervical Transpedicular System for Reconstruction of Cervical Stability After Subtotal Resection of Two Segments of Lower Cervical Spine] Zhongguo Gu Shang = China Journal of Orthopaedics and Traumatology. Feb, 2022 | Pubmed ID: 35191273 Destabilization of Macrophage Migration Inhibitory Factor by 4-IPP Reduces NF-κB/P-TEFb Complex-mediated C-Myb Transcription to Suppress Osteosarcoma Tumourigenesis Clinical and Translational Medicine. Jan, 2022 | Pubmed ID: 35060345 Comparison of Oblique Lateral Interbody Fusion (OLIF) and Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF) for Treatment of Lumbar Degeneration Disease: A Prospective Cohort Study Spine. Mar, 2022 | Pubmed ID: 34855704 Learning-based Fully Automated Prediction of Lumbar Disc Degeneration Progression with Specified Clinical Parameters and Preliminary Validation European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Aug, 2022 | Pubmed ID: 34657211 Poor Bone Quality, Multilevel Surgery, and Narrow and Tall Cages Are Associated with Intraoperative Endplate Injuries and Late-onset Cage Subsidence in Lateral Lumbar Interbody Fusion: A Systematic Review Clinical Orthopaedics and Related Research. Jan, 2022 | Pubmed ID: 34324459 EIF4A3-induced Circular RNA PRKAR1B Promotes Osteosarcoma Progression by MiR-361-3p-mediated Induction of FZD4 Expression Cell Death & Disease. Oct, 2021 | Pubmed ID: 34716310 Identification of Circular RNAs Related to Vascular Endothelial Proliferation, Migration, and Angiogenesis After Spinal Cord Injury Using Microarray Analysis in Female Mice Frontiers in Neurology. 2021 | Pubmed ID: 34539543 [Short-segment Pedicle Screw Fixation Combined with Vertebroplasty for the Treatment of Kümmell Disease with Kyphosis] Zhongguo Gu Shang = China Journal of Orthopaedics and Traumatology. Aug, 2021 | Pubmed ID: 34423610 RCAN1.4 Suppresses the Osteosarcoma Growth and Metastasis Via Interfering with the Calcineurin/NFAT Signaling Pathway Journal of Bone Oncology. Oct, 2021 | Pubmed ID: 34336566 The Correlation Between the Change of Hounsfield Units Value and Modic Changes in the Lumbar Vertebral Endplate BMC Musculoskeletal Disorders. Jun, 2021 | Pubmed ID: 34078344 Anteroinferior Psoas Technique for Oblique Lateral Lumbar Interbody Fusion Orthopaedic Surgery. Jun, 2021 | Pubmed ID: 33951305 [Comparative Study Between 3D Guide Plate Assisted and Free-hand Insertion of Anterior Cervical Transpedicular Screw] Zhongguo Gu Shang = China Journal of Orthopaedics and Traumatology. Jan, 2021 | Pubmed ID: 33666019 Endplate Injury As a Risk Factor for Cage Retropulsion Following Transforaminal Lumbar Interbody Fusion: An Analysis of 1052 Cases Medicine. Feb, 2021 | Pubmed ID: 33592856 Anteroinferior Psoas Technique for Oblique Lateral Lumbar Interbody Fusion: Technical Note and Case Series Orthopaedic Surgery. Apr, 2021 | Pubmed ID: 33507614 Site-1 Protease Controls Osteoclastogenesis by Mediating LC3 Transcription Cell Death and Differentiation. Jun, 2021 | Pubmed ID: 33469231 Importance of the Epiphyseal Ring in OLIF Stand-alone Surgery: a Biomechanical Study on Cadaveric Spines European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Jan, 2021 | Pubmed ID: 33226482 Damage to the Human Lumbar Cartilage Endplate and Its Clinical Implications Journal of Anatomy. Feb, 2021 | Pubmed ID: 33011984 Systemic Bone Loss Following Myocardial Infarction in Mice Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Apr, 2021 | Pubmed ID: 32965732 Homocysteine Induces Oxidative Stress and Ferroptosis of Nucleus Pulposus Via Enhancing Methylation of GPX4 Free Radical Biology & Medicine. Nov, 2020 | Pubmed ID: 32896601 Osteal Tissue Macrophages Are Involved in Endplate Osteosclerosis Through the OSM-STAT3/YAP1 Signaling Axis in Modic Changes Journal of Immunology (Baltimore, Md. : 1950). Aug, 2020 | Pubmed ID: 32690652 The Influence of Long-term Shoulder Loading on Sagittal Spino-pelvic Morphology: a Population-based Retrospective Study of Chinese Farmers from Radiology Journal of Orthopaedic Surgery and Research. May, 2020 | Pubmed ID: 32471454 The RCAN1.4-calcineurin/NFAT Signaling Pathway is Essential for Hypoxic Adaption of Intervertebral Discs Experimental & Molecular Medicine. May, 2020 | Pubmed ID: 32467610 Lubricin Expression in the Lumbar Endplate and Its Association with Modic Changes Journal of Orthopaedic Translation. May, 2020 | Pubmed ID: 32440508 Recurrent Disc Herniation Following Percutaneous Endoscopic Lumbar Discectomy Preferentially Occurs when Modic Changes Are Present Journal of Orthopaedic Surgery and Research. May, 2020 | Pubmed ID: 32410638 Retraction Note To: The Association Between Modic Changes of Lumbar Endplates and Spontaneous Absorption of Herniated Intervertebral Discs Cell Biochemistry and Biophysics. Sep, 2020 | Pubmed ID: 32297207 Reoccurring Discogenic Low Back Pain (LBP) After Discoblock Treated by Oblique Lumbar Interbody Fusion (OLIF) Journal of Orthopaedic Surgery and Research. Jan, 2020 | Pubmed ID: 31959197 One-stage Debridement Via Oblique Lateral Interbody Fusion Corridor Combined with Posterior Pedicle Screw Fixation in Treating Spontaneous Lumbar Infectious Spondylodiscitis: A Case Series Orthopaedic Surgery. Dec, 2019 | Pubmed ID: 31701667 Obesity Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances Via MAPK Pathway Activation in Intervertebral Disk Degeneration Frontiers in Physiology. 2019 | Pubmed ID: 31649558 Administration of SB239063 Ameliorates Ovariectomy-Induced Bone Loss Suppressing Osteoclastogenesis in Mice Frontiers in Pharmacology. 2019 | Pubmed ID: 31474861 Percutaneous Kyphoplasty: Risk Factors for Recollapse of Cemented Vertebrae World Neurosurgery. Oct, 2019 | Pubmed ID: 31226459 Changes in the Flexion-Relaxation Response After Percutaneous Endoscopic Lumbar Discectomy in Patients with Disc Herniation World Neurosurgery. May, 2019 | Pubmed ID: 30776518 Association Between Modic Changes and Endplate Sclerosis: Evidence from a Clinical Radiology Study and a Rabbit Model Journal of Orthopaedic Translation. Jan, 2019 | Pubmed ID: 30723683 IL-6/YAP1/β-catenin Signaling is Involved in Intervertebral Disc Degeneration Journal of Cellular Physiology. May, 2019 | Pubmed ID: 30511395 Alpha 2-Macroglobulin As Dual Regulator for Both Anabolism and Catabolism in the Cartilaginous Endplate of Intervertebral Disc Spine. Mar, 2019 | Pubmed ID: 30138255 Answer to the Letter to the Editor of Manu N. Capoor Et Al. Concerning "Low Virulence Bacterial Infections in Cervical Intervertebral Discs: a Prospective Case Series" by Chen Y, Wang X, Zhang X, Et Al. (Eur Spine J; 2018: Doi: 10.1007/s00586-018-5582-4) European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. May, 2019 | Pubmed ID: 29959552 Mechanism of Formation of Intravertebral Clefts in Osteoporotic Vertebral Compression Fractures: An in Vitro Biomechanical Study The Spine Journal : Official Journal of the North American Spine Society. Dec, 2018 | Pubmed ID: 30075299 Complications and Prevention Strategies of Oblique Lateral Interbody Fusion Technique Orthopaedic Surgery. May, 2018 | Pubmed ID: 29878716 Low Virulence Bacterial Infections in Cervical Intervertebral Discs: a Prospective Case Series European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Oct, 2018 | Pubmed ID: 29675672 The Six-Step Lower Blepharoplasty: Using Fractionated Fat to Enhance Blending of the Lid-Cheek Junction Plastic and Reconstructive Surgery. Mar, 2018 | Pubmed ID: 29485587 Superior Cortical Screw in Osteoporotic Lumbar Vertebrae: A Biomechanics and Microstructure-based Study Clinical Biomechanics (Bristol, Avon). Mar, 2018 | Pubmed ID: 29407351 The Mechanism of Thoracolumbar Burst Fracture May Be Related to the Basivertebral Foramen The Spine Journal : Official Journal of the North American Spine Society. Mar, 2018 | Pubmed ID: 28823938 Painful Schmorl's Nodes Treated by Discography and Discoblock European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Jan, 2018 | Pubmed ID: 28194524 Accuracy of Pedicle Screw Placement in Posterior Lumbosacral Instrumentation by Computer Tomography Evaluation: A Multi-centric Retrospective Clinical Study International Journal of Surgery (London, England). Jul, 2017 | Pubmed ID: 28546099 An Injectable Nucleus Pulposus Cell-modified Decellularized Scaffold: Biocompatible Material for Prevention of Disc Degeneration Oncotarget. Jun, 2017 | Pubmed ID: 28402966 Propionibacterium Acnes Incubation in the Discs Can Result in Time-Dependent Modic Changes: A Long-Term Rabbit Model Spine. Nov, 2017 | Pubmed ID: 28399545 The Influence of Direct Inoculation of Propionibacterium Acnes on Modic Changes in the Spine: Evidence from a Rabbit Model The Journal of Bone and Joint Surgery. American Volume. Mar, 2017 | Pubmed ID: 28291179 Comparison of Pedicle Fixation by the Wiltse Approach and the Conventional Posterior Open Approach for Thoracolumbar Fractures, Using MRI, Histological and Electrophysiological Analyses of the Multifidus Muscle European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. May, 2017 | Pubmed ID: 28247080 Does the High-intensity Zone (HIZ) of Lumbar Intervertebral Discs Always Represent an Annular Fissure? European Radiology. Mar, 2017 | Pubmed ID: 27260341 Effect of Pure Muscle Retraction on Multifidus Injury and Atrophy After Posterior Lumbar Spine Surgery with 24 weeks Observation in a Rabbit Model European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Jan, 2017 | Pubmed ID: 26687124 Mini-open Anterior Lumbar Interbody Fusion for Recurrent Lumbar Disc Herniation Following Posterior Instrumentation Spine. Sep, 2016 | Pubmed ID: 26987108 Biomechanical Properties of Lumbar Endplates and Their Correlation with MRI Findings of Lumbar Degeneration Journal of Biomechanics. Feb, 2016 | Pubmed ID: 26892896 Prevalence and Risk Factors of Deep Vein Thrombosis in Patients Undergoing Lumbar Interbody Fusion Surgery: A Single-Center Cross-Sectional Study Medicine. Dec, 2015 | Pubmed ID: 26632909 Anchorage of Annulus Fibrosus Within the Vertebral Endplate with Reference to Disc Herniation Microscopy Research and Technique. Sep, 2015 | Pubmed ID: 26178646 Prevalence and Risk Factors of Deep Vein Thrombosis in Patients After Spine Surgery: a Retrospective Case-cohort Study Scientific Reports. Jul, 2015 | Pubmed ID: 26135271 Correlation Between Biomechanical Properties of the Annulus Fibrosus and Magnetic Resonance Imaging (MRI) Findings European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Sep, 2015 | Pubmed ID: 26088178 Anterior Decompression and Reconstruction for Lumbar Burst Fractures Orthopaedic Surgery. May, 2015 | Pubmed ID: 26034003 Anterior Decompression and Strut Grafting for Adjacent Segment Disease Nine Years After Posterior Lumbar Interbody Fusion Orthopaedic Surgery. May, 2015 | Pubmed ID: 26034000 Re: The Anatomy of Failure in Lumbar Disc Herniation Spine. Jul, 2015 | Pubmed ID: 25909353 Re: Identification of Risk Factors for the Occurrence of Cement Leakage During Percutaneous Vertebroplasty for Painful Osteoporotic or Malignant Vertebral Fracture Spine. Jul, 2015 | Pubmed ID: 25909348 Evaluation of 12 Novel Molecular Markers for Degenerated Nucleus Pulposus in a Chinese Population Spine. Aug, 2015 | Pubmed ID: 25893345 The Association Between Modic Changes of Lumbar Endplates and Spontaneous Absorption of Herniated Intervertebral Discs Cell Biochemistry and Biophysics. Apr, 2015 | Pubmed ID: 25564357 Comparison of Modic Changes in the Lumbar and Cervical Spine, in 3167 Patients with and Without Spinal Pain PloS One. 2014 | Pubmed ID: 25506944 Pathomechanism of Intravertebral Clefts in Osteoporotic Compression Fractures of the Spine: Basivertebral Foramen Collapse Might Cause Intravertebral Avascular Necrosis The Spine Journal : Official Journal of the North American Spine Society. Jun, 2014 | Pubmed ID: 24851741 Percutaneous Balloon Kyphoplasty of Osteoporotic Vertebral Compression Fractures with Intravertebral Cleft Indian Journal of Orthopaedics. Jan, 2014 | Pubmed ID: 24600064 Minimally Invasive Anterior Lumbar Interbody Fusion for Adjacent Segment Disease After Posterior Lumbar Fusion Orthopaedic Surgery. Feb, 2014 | Pubmed ID: 24591000 Accuracy of Magnetic Resonance Imaging Signal Intensity Ratio Measurements in the Evaluation of Multifidus Muscle Injury and Atrophy Relative to That of Histological Examinations Spine. May, 2014 | Pubmed ID: 24583730 Spontaneous Resorption of Lumbar Disc Herniation is Less Likely when Modic Changes Are Present Spine. Apr, 2014 | Pubmed ID: 24503683 Basivertebral Foramen Could Be Connected with Intravertebral Cleft: a Potential Risk Factor of Cement Leakage in Percutaneous Kyphoplasty The Spine Journal : Official Journal of the North American Spine Society. Aug, 2014 | Pubmed ID: 24314766 Effect and Possible Mechanism of Muscle-splitting Approach on Multifidus Muscle Injury and Atrophy After Posterior Lumbar Spine Surgery The Journal of Bone and Joint Surgery. American Volume. Dec, 2013 | Pubmed ID: 24352778 Can Posterior Dynamic Stabilization Reduce the Risk of Adjacent Segment Deterioration? Turkish Neurosurgery. 2013 | Pubmed ID: 24101303 Cage Migration After Transforaminal Lumbar Interbody Fusion and Factors Related to It Orthopaedic Surgery. Nov, 2012 | Pubmed ID: 23109307 Quantitative MRI Analysis of the Surface Area, Signal Intensity and MRI Index of the Central Bright Area for the Evaluation of Early Adjacent Disc Degeneration After Lumbar Fusion European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Sep, 2012 | Pubmed ID: 22526697 [Limb Preservation Surgery Combined with Perioperative Rehabilitation for the Treatment of 7 Patients with Stage II to III Giant Cell Tumor of Bone in the Proximal Humerus] Zhongguo Gu Shang = China Journal of Orthopaedics and Traumatology. Dec, 2011 | Pubmed ID: 22276517 Intraoperative Malposition of Pedicle Probe or Screws: a Potential Cause of the Acceleration of Degeneration in Superior Adjacent Intervertebral Disc Medical Hypotheses. Dec, 2011 | Pubmed ID: 21968276 Meta-analysis of Instrumented Posterior Interbody Fusion Versus Instrumented Posterolateral Fusion in the Lumbar Spine Journal of Neurosurgery. Spine. Sep, 2011 | Pubmed ID: 21619404 An Assessment of the Intra- and Inter-reliability of the Lumbar Paraspinal Muscle Parameters Using CT Scan and Magnetic Resonance Imaging Spine. Jun, 2011 | Pubmed ID: 21224757 Comparison of Paraspinal Muscle Injury in One-level Lumbar Posterior Inter-body Fusion: Modified Minimally Invasive and Traditional Open Approaches Orthopaedic Surgery. Aug, 2010 | Pubmed ID: 22009948 Traumatic Canal Stenosis Should Not Be an Indication for Surgical Decompression in Thoracolumbar Burst Fracture Medical Hypotheses. Dec, 2010 | Pubmed ID: 20708338 Minimally Invasive Transforaminal Lumbar Interbody Fusion for the Treatment of Degenerative Lumbar Diseases Spine. Aug, 2010 | Pubmed ID: 20479702 [Changes of Nucleus Pulposus After Culture of Whole Intervertebral Discs] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery. Apr, 2010 | Pubmed ID: 20458996 Multifidus Muscle Changes and Clinical Effects of One-level Posterior Lumbar Interbody Fusion: Minimally Invasive Procedure Versus Conventional Open Approach European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Feb, 2010 | Pubmed ID: 19876659 [In Vivo Study of Innervation of Degenerative Intervertebral Discs in Rabbit Anular-injury Model] Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. Sep, 2009 | Pubmed ID: 19830861 Modic Changes, Possible Causes and Promotion to Lumbar Intervertebral Disc Degeneration Medical Hypotheses. Dec, 2009 | Pubmed ID: 19632056 Orthopaedic . Radiology . Pathology Conference: Left Hip Pain in a 62-year-old Man Clinical Orthopaedics and Related Research. Jul, 2009 | Pubmed ID: 18780134 [Clinical Value of Minimally Invasive Posterior Lumbar Interbody Fusion Assisted by X-Tube System in the Treatment of Low Back Disorders] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Apr, 2008 | Pubmed ID: 18785555 [Modified Posterior-anterior Operation for Treatment of Serious Lumbar Fracture and Dislocation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery. Aug, 2008 | Pubmed ID: 18773803 Mesenchymal Chondrosarcoma of the Talus: a Case Report Foot & Ankle International. Oct, 2007 | Pubmed ID: 17923063 [The Feature of Experimental Endplate Fracture in Lumbar Spine and Its Related Factors] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Aug, 2006 | Pubmed ID: 17081472 Discogenic Origins of Spinal Instability Spine. Dec, 2005 | Pubmed ID: 16319748 [Anterior Instrumentation for the Treatment of Tuberculotic Spinal Deformity] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Apr, 2003 | Pubmed ID: 12882676 Modic Changes (MCs) Associated with Endplate Sclerosis Can Prevent Cage Subsidence in Oblique Lumbar Interbody Fusion (OLIF) Stand-Alone World Neurosurgery. | Pubmed ID: 32081816 Trabecular Microstructure and Damage Affect Cement Leakage From the Basivertebral Foramen During Vertebral Augmentation Spine. | Pubmed ID: 28098744 Laminectomy for the Removal of Thoracic Ossification of the Ligamentum Flavum (TOLF) Using Ultrasonic and Conventional Osteotomes Junhui Liu1,2, Zhi Shan1,2, Yilei Chen1,2, Fengdong Zhao1,2 1Department of Orthopedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 2Key Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province JoVE 64339 Medicina
Laminectomy for the Removal of Thoracic Ossification of the Ligamentum Flavum (TOLF) Using Ultrasonic and Conventional Osteotomes Junhui Liu1,2, Zhi Shan1,2, Yilei Chen1,2, Fengdong Zhao1,2 1Department of Orthopedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 2Key Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province JoVE 64339 Medicina