Rui Wang Science and Technology Innovation Center Guangzhou University of Chinese Medicine Biography Publications Institution JoVE Articles Rui Wang has not added a biography. If you are Rui Wang and would like to personalize this page please email our Author Liaison for assistance. Publications Integrative Analysis of Multi-Omic Data for the Characteristics of Endometrial Cancer ACS Omega. Mar, 2024 | Pubmed ID: 38559975 Protective Effect of Huangqi-Guizhi-Wuwutang Against Cyclophosphamide-induced Spermatogenesis Dysfunction in Mice by Promoting Steroid Hormone Biosynthesis Journal of Ethnopharmacology. Jan, 2024 | Pubmed ID: 37813291 FZKA Reverses Gefitinib Resistance by Regulating EZH2/Snail/EGFR Signaling Pathway in Lung Adenocarcinoma Journal of Ethnopharmacology. Jan, 2024 | Pubmed ID: 37269912 Mechanisms of 3-Hydroxyl 3-Methylglutaryl CoA Reductase in Alzheimer's Disease International Journal of Molecular Sciences. Dec, 2023 | Pubmed ID: 38203341 Kaempferol Promotes Non-small Cell Lung Cancer Cell Autophagy Via Restricting Met Pathway Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Dec, 2023 | Pubmed ID: 37738907 HLA-I Evolutionary Divergence Confers Response to PD-1 Blockade Plus Chemotherapy in Untreated Advanced Non-Small Cell Lung Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2023 | Pubmed ID: 37449971 Multimodal and Multiscale Evidence for Network-based Cortical Thinning in Major Depressive Disorder NeuroImage. Aug, 2023 | Pubmed ID: 37414234 Impaired Colonic Motility in High-glycemic Diet-induced Diabetic Mice is Associated with Disrupted Gut Microbiota and Neuromuscular Function Endocrine Connections. Aug, 2023 | Pubmed ID: 37399524 Regulating Lactate-related Immunometabolism and EMT Reversal for Colorectal Cancer Liver Metastases Using Shikonin Targeted Delivery Journal of Experimental & Clinical Cancer Research : CR. May, 2023 | Pubmed ID: 37161591 Solamargine Enhanced Gefitinib Antitumor Effect Via Regulating MALAT1/miR-141-3p/Sp1/IGFBP1 Signaling Pathway in Non-small Cell Lung Cancer Carcinogenesis. Aug, 2023 | Pubmed ID: 37144780 Jian-Pi-Yi-Shen Formula Restores Iron Metabolism from Dysregulation in Anemic Rats with Adenine-induced Nephropathy Journal of Ethnopharmacology. Aug, 2023 | Pubmed ID: 37088234 Fuzheng Kang-Ai Inhibits NSCLC Cell Proliferation Via Regulating Hsa_circ_0048091/hsa-miR-378g/ARRDC3 Pathway Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Jun, 2023 | Pubmed ID: 37062135 TRPV1 Dysfunction Impairs Gastric Nitrergic Neuromuscular Relaxation in High-Fat Diet-Induced Diabetic Gastroparesis Mice The American Journal of Pathology. May, 2023 | Pubmed ID: 36740184 Release of STK24/25 Suppression on MEKK3 Signaling in Endothelial Cells Confers Cerebral Cavernous Malformation JCI Insight. Jan, 2023 | Pubmed ID: 36692953 Activated Hepatic Nuclear Factor-κB in Experimental Colitis Regulates CYP2A5 and Metronidazole Disposition Molecular Pharmaceutics. Feb, 2023 | Pubmed ID: 36583631 Novel Feleucin-K3-Derived Peptides Modified with Sulfono-γ-AA Building Blocks Targeting and Methicillin-Resistant Infections Journal of Medicinal Chemistry. Jan, 2023 | Pubmed ID: 36350686 NaClO-Mediated Cross Installation of Indoles and Azoles Benefits Anticancer Hit Discovery ChemMedChem. Dec, 2022 | Pubmed ID: 36585386 Vanilloid Agonist-mediated Activation of TRPV1 Channels Requires Coordinated Movement of the S1-S4 Bundle Rather Than a Quiescent State Science Bulletin. May, 2022 | Pubmed ID: 36546250 Copper(I)-Catalyzed Late-Stage Introduction of Oxime Ethers into Peptides at the Carboxylic Acid Site Organic Letters. Dec, 2022 | Pubmed ID: 36508502 Suo Quan Wan Ameliorates Bladder Overactivity and Regulates Neurotransmission Via Regulating Myosin Va Protein Expression Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Sep, 2022 | Pubmed ID: 35763954 Danggui-Shaoyao-San Attenuates Cognitive Impairment the Microbiota-Gut-Brain Axis With Regulation of Lipid Metabolism in Scopolamine-Induced Amnesia Frontiers in Immunology. 2022 | Pubmed ID: 35664001 Molecular Dynamics Simulations of Adsorption Behavior of DDAH, NaOL and Mixed DDAH/NaOL Surfactants on Muscovite (001) Surface in Aqueous Solution Journal of Molecular Graphics & Modelling. 06, 2022 | Pubmed ID: 35298946 Therapeutic Peptides: Current Applications and Future Directions Signal Transduction and Targeted Therapy. Feb, 2022 | Pubmed ID: 35165272 Synovial Calprotectin for the Diagnosis of Periprosthetic Joint Infection: a Diagnostic Meta-analysis Journal of Orthopaedic Surgery and Research. Jan, 2022 | Pubmed ID: 34983582 Model Construction and Application for Effluent Prediction in Wastewater Treatment Plant: Data Processing Method Optimization and Process Parameters Integration Journal of Environmental Management. Jan, 2022 | Pubmed ID: 34731713 Low-Dose Cyclophosphamide Induces Nerve Injury and Functional Overactivity in the Urinary Bladder of Rats Frontiers in Neuroscience. 2021 | Pubmed ID: 34658764 Small-Molecule Inhibitors Overcome Epigenetic Reprogramming for Cancer Therapy Frontiers in Pharmacology. 2021 | Pubmed ID: 34603017 Discovery of Pyrazole N-aryl Sulfonate: A Novel and Highly Potent Cyclooxygenase-2 (COX-2) Selective Inhibitors Bioorganic & Medicinal Chemistry. Sep, 2021 | Pubmed ID: 34438337 Copper Catalyzed Late-stage C(sp)-H Functionalization of Nitrogen Heterocycles Nature Communications. Jul, 2021 | Pubmed ID: 34267229 Uptake, Transport, and Metabolism of Selenium and Its Protective Effects Against Toxic Metals in Plants: a Review Metallomics : Integrated Biometal Science. Jul, 2021 | Pubmed ID: 34180517 Rapid-flow Expulsion Maneuver in Subglottic Secretion Clearance to Prevent Ventilator-associated Pneumonia: a Randomized Controlled Study Annals of Intensive Care. Jun, 2021 | Pubmed ID: 34165661 Durable Endothelium-mimicking Coating for Surface Bioengineering Cardiovascular Stents Bioactive Materials. Dec, 2021 | Pubmed ID: 34095629 A PRC2-independent Function for EZH2 in Regulating RRNA 2'-O Methylation and IRES-dependent Translation Nature Cell Biology. Apr, 2021 | Pubmed ID: 33795875 Contribution of the μ Opioid Receptor and Enkephalin to the Antinociceptive Actions of Endomorphin-1 Analogs with Unnatural Amino Acid Modifications in the Spinal Cord Peptides. Jul, 2021 | Pubmed ID: 33794284 Editing the Immune System in Vivo in Mice Using CRISPR/Cas9 Ribonucleoprotein (RNP)-mediated Gene Editing of Transplanted Hematopoietic Stem Cells Methods (San Diego, Calif.). Jan, 2021 | Pubmed ID: 33422676 Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans Cell Metabolism. Feb, 2021 | Pubmed ID: 33186557 Cryptotanshinone Alleviates Chemotherapy-induced Colitis in Mice with Colon Cancer Via Regulating Fecal-bacteria-related Lipid Metabolism Pharmacological Research. Jan, 2021 | Pubmed ID: 33027716 Hydrocarbon Staple Constructing Highly Efficient α-helix Cell-penetrating Peptides for Intracellular Cargo Delivery Chemical Communications (Cambridge, England). Dec, 2020 | Pubmed ID: 33355559 Research Trends and Hotspots of High Tibial Osteotomy in Two Decades (from 2001 to 2020): a Bibliometric Analysis Journal of Orthopaedic Surgery and Research. Nov, 2020 | Pubmed ID: 33168047 Diabetic Bladder Dysfunction in T2D KK-Ay Mice and Its Changes in the Level of Relevant Gene Expression Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Nov, 2020 | Pubmed ID: 33152907 Preparation of Phospholipid-based Polycarbonate Urethanes for Potential Applications of Blood-contacting Implants Regenerative Biomaterials. Oct, 2020 | Pubmed ID: 33149938 Phospholipid-based Multifunctional Coating Via Layer-by-layer Self-assembly for Biomedical Applications Materials Science & Engineering. C, Materials for Biological Applications. Nov, 2020 | Pubmed ID: 32806322 NRP1 Regulates Radiation-induced EMT Via TGF-β/Smad Signaling in Lung Adenocarcinoma Cells International Journal of Radiation Biology. Oct, 2020 | Pubmed ID: 32659143 [Establishing the Blood Donor Deferral Criterion in TP ELISA Test] Zhongguo Shi Yan Xue Ye Xue Za Zhi. Jun, 2020 | Pubmed ID: 32552964 Dihydrotanshinone Attenuates Chemotherapy-induced Intestinal Mucositis and Alters Fecal Microbiota in Mice Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Aug, 2020 | Pubmed ID: 32447214 Activation of Allylic Esters in an Intramolecular Vinylogous Kinetic Resolution Reaction with Synergistic Magnesium Catalysts Nature Communications. May, 2020 | Pubmed ID: 32444612 Asymmetric N-aminoalkylation of 3-substituted Indoles by N-protected N,O-acetals: an Access to Chiral Propargyl Aminals Organic & Biomolecular Chemistry. Jun, 2020 | Pubmed ID: 32436514 Design, Synthesis, and Biological Activity of New Endomorphin Analogs with Multi-site Modifications Bioorganic & Medicinal Chemistry. May, 2020 | Pubmed ID: 32199689 CRISPR/Cas9-targeting of CD40 in Hematopoietic Stem Cells Limits Immune Activation Mediated by Anti-CD40 PloS One. 2020 | Pubmed ID: 32155151 MEL Endomorphins Act As Potent Inflammatory Analgesics with the Inhibition of Activated Non-neuronal Cells and Modulation of Pro-inflammatory Cytokines Neuropharmacology. May, 2020 | Pubmed ID: 32036072 Catalytic Asymmetric Multiple Dearomatizations of Phenols Enabled by a Cascade 1,8-addition and Diels-Alder Reaction Chemical Science. Dec, 2019 | Pubmed ID: 34123039 Baicalein Administered in the Subacute Phase Ameliorates Ischemia-reperfusion-induced Brain Injury by Reducing Neuroinflammation and Neuronal Damage Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Sep, 2019 | Pubmed ID: 31228802 Suo Quan Wan Protects Mouse From Early Diabetic Bladder Dysfunction by Mediating Motor Protein Myosin Va and Transporter Protein SLC17A9 Frontiers in Pharmacology. 2019 | Pubmed ID: 31178730 Time-dependent Functional, Morphological, and Molecular Changes in Diabetic Bladder Dysfunction in Streptozotocin-induced Diabetic Mice Neurourology and Urodynamics. 06, 2019 | Pubmed ID: 31006139 Development of Drug-inducible CRISPR-Cas9 Systems for Large-scale Functional Screening BMC Genomics. Mar, 2019 | Pubmed ID: 30890156 Comparative Analysis on Adsorption Properties and Mechanisms of Nitrate and Phosphate by Modified Corn Stalks RSC Advances. Oct, 2018 | Pubmed ID: 35558905 Arylation of Benzyl Amines with Aromatic Nitriles Chemical Communications (Cambridge, England). Oct, 2018 | Pubmed ID: 30283923 [Utility of Preoperative Voice Therapy on the Voice Recovery of Vocal Cord Polyps Patients Undergoing the Microsurgery] Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery. Mar, 2018 | Pubmed ID: 29737733 Regio- and Stereospecific Friedel-Crafts Alkylation of Indoles with Spiro-epoxyoxindoles Organic & Biomolecular Chemistry. May, 2018 | Pubmed ID: 29714392 Druggable Negative Allosteric Site of P2X3 Receptors Proceedings of the National Academy of Sciences of the United States of America. May, 2018 | Pubmed ID: 29674445 Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth Molecular Cancer Therapeutics. May, 2018 | Pubmed ID: 29483218 Determination of IMM-H004 and Its Active Glucuronide Metabolite in Rat Plasma and Ringer's Solution by Ultra-performance Liquid Chromatography-tandem Mass Spectrometry Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Feb, 2018 | Pubmed ID: 29329091 CB Cannabinoid Receptor Agonist Mouse VD-hemopressin(α) Produced Supraspinal Analgesic Activity in the Preclinical Models of Pain Brain Research. Feb, 2018 | Pubmed ID: 29274880 The in Vitro, in Vivo Antifungal Activity and the Action Mode of Jelleine-I Against Candida Species Amino Acids. Feb, 2018 | Pubmed ID: 29101485 Photoinduced, Copper-catalyzed Three Components Cyanofluoroalkylation of Alkenes with Fluoroalkyl Iodides As Fluoroalkylation Reagents Chemical Communications (Cambridge, England). Nov, 2017 | Pubmed ID: 29095444 Flavones and Lignans from the Stems of Diels Pharmacognosy Magazine. Jul-Sep, 2017 | Pubmed ID: 28839377 Peripheral and Central Sites of Action for Anti-allodynic Activity Induced by the Bifunctional Opioid/NPFF Receptors Agonist BN-9 in Inflammatory Pain Model European Journal of Pharmacology. Oct, 2017 | Pubmed ID: 28755985 Endomorphin-1 Analogs Containing α-methyl-β-amino Acids Exhibit Potent Analgesic Activity After Peripheral Administration Organic & Biomolecular Chemistry. Jun, 2017 | Pubmed ID: 28567467 Rare Loss-of-Function Variants in NPC1 Predispose to Human Obesity Diabetes. Apr, 2017 | Pubmed ID: 28130309 Effects of Platycodin D on Proliferation, Apoptosis and PI3K/Akt Signal Pathway of Human Glioma U251 Cells Molecules (Basel, Switzerland). Dec, 2014 | Pubmed ID: 25532840 Rapid Turnover of 2-LTR HIV-1 DNA During Early Stage of Highly Active Antiretroviral Therapy PloS One. 2011 | Pubmed ID: 21687638 FoxO1 Represses LXRα-mediated Transcriptional Activity of SREBP-1c Promoter in HepG2 Cells FEBS Letters. Oct, 2010 | Pubmed ID: 20868688 Sirtuin 3, a New Target of PGC-1alpha, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis PloS One. Jul, 2010 | Pubmed ID: 20661474 Sterol-regulatory-element-binding Protein 1c Mediates the Effect of Insulin on the Expression of Cidea in Mouse Hepatocytes The Biochemical Journal. Sep, 2010 | Pubmed ID: 20575761 Function of SIRT1 in Physiology Biochemistry. Biokhimiia. Jul, 2009 | Pubmed ID: 19747089 Peroxisome Proliferator-activated Receptor Gamma Coactivator-1alpha Enhances Antiproliferative Activity of 5'-deoxy-5-fluorouridine in Cancer Cells Through Induction of Uridine Phosphorylase Molecular Pharmacology. Oct, 2009 | Pubmed ID: 19602572 Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment Chuyao Huang1, Rui Wang1, Jinhan Lv1, Ningxiang Zheng1, Zhenwen Wei1, Xiaolang Wu1, Qi Wang1, Wei Zhao1,2 1Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, 2Maoming Hospital of Guangzhou University of Chinese Medicine JoVE 65969 Medicina Development of a 68Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression Lulu Zhang*1, Siqi Zhang*2, Wenyu Wu1, Xingkai Wang2, Jieting Shen2, Dongyuan Wang4, Kuan Hu*2,3, Ming-Rong Zhang*3, Feng Wang*1, Rui Wang*2 1Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, 2State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 3Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, 4Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology JoVE 65047 Investigación sobre el cáncer Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers Dan Fang1, Rui Wang1, Xinyi Yu1, Yuan Tian1 1Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University JoVE 64293 Química Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies Sean Graham1, Lei Gao1, Rui Wang1 1AbbVie, Cambridge Research Center JoVE 61618 Inmunología e infección Isolation and Culture of Primary Neurons and Glia from Adult Rat Urinary Bladder Rui Wang1, Zi-tong Huang3, Wen-kang Ren1, Jiao Zhang1, Yao Zhang1, Bo Tan3, Ping Huang1,2, Hong-ying Cao1,2 1School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 2Dongguan & Guangzhou University of Chinese Medicine Cooperative Academy of Mathematical Engineering for Chinese Medicine, Guangzhou University of Chinese Medicine, 3School of Basic Medical Sciences, Guangzhou University of Chinese Medicine JoVE 61177 Neurociencia
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment Chuyao Huang1, Rui Wang1, Jinhan Lv1, Ningxiang Zheng1, Zhenwen Wei1, Xiaolang Wu1, Qi Wang1, Wei Zhao1,2 1Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, 2Maoming Hospital of Guangzhou University of Chinese Medicine JoVE 65969 Medicina
Development of a 68Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression Lulu Zhang*1, Siqi Zhang*2, Wenyu Wu1, Xingkai Wang2, Jieting Shen2, Dongyuan Wang4, Kuan Hu*2,3, Ming-Rong Zhang*3, Feng Wang*1, Rui Wang*2 1Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, 2State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 3Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, 4Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology JoVE 65047 Investigación sobre el cáncer
Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers Dan Fang1, Rui Wang1, Xinyi Yu1, Yuan Tian1 1Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University JoVE 64293 Química
Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies Sean Graham1, Lei Gao1, Rui Wang1 1AbbVie, Cambridge Research Center JoVE 61618 Inmunología e infección
Isolation and Culture of Primary Neurons and Glia from Adult Rat Urinary Bladder Rui Wang1, Zi-tong Huang3, Wen-kang Ren1, Jiao Zhang1, Yao Zhang1, Bo Tan3, Ping Huang1,2, Hong-ying Cao1,2 1School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 2Dongguan & Guangzhou University of Chinese Medicine Cooperative Academy of Mathematical Engineering for Chinese Medicine, Guangzhou University of Chinese Medicine, 3School of Basic Medical Sciences, Guangzhou University of Chinese Medicine JoVE 61177 Neurociencia
