Universidad CEU Cardenal Herrera 3 articles published in JoVE Bioengineering Human Liver Spheroids from Peripheral Blood for Liver Disease Studies Anne-Kathrin Schott1, Ivan Zipančić2, Vicente Hernández-Rabaza2, Zorica A. Becker-Kojić1 1ACA CELL Biotech GmbH, 2Departamento Ciencias Biomédicas, Universidad Cardenal Herrera-CEU Here we present a non-genetic method to generate human autologous liver spheroids using mononuclear cells isolated from steady-state peripheral blood. Neuroscience GM-Free Generation of Blood-Derived Neuronal Cells Zorica A. Becker-Kojić1, Anne-Kathrin Schott1, Ivan Zipančić2, Vicente Hernández-Rabaza2 1ACA CELL Biotech GmbH, 2Departmento Ciencias Biomedicas, Universidad Cardenal Herrera-CEU We present a genetically modified-free (GM-free) method to obtain cells with a neuronal phenotype from reprogrammed peripheral blood cells. Activation of a signaling pathway linked to novel human GPI-linked protein reveals an efficient GM-free method for obtaining human pluripotent stem cells. Behavior A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment Francisco J. Muñoz-Almaraz1, María Teresa Climent2, María Dolores Guerrero3, Lucrecia Moreno3, Juan Pardo1 1Embedded Systems and Artificial Intelligence Group, Universidad CEU Cardenal Herrera, 2Community Pharmacist, 3Department of Pharmacy, Universidad CEU Cardenal Herrera This methodology produces decision trees that target population groups more prone to suffering from mild cognitive impairment and are useful for cost-effective selective screening of the disease.