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Journal / Immunology and Infection / 微链 rna 的共聚焦成像和模式识别受体在负感 rna…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
微链 rna 的共聚焦成像和模式识别受体在负感 rna 病毒感染中的应用
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微链 rna 的共聚焦成像和模式识别受体在负感 rna 病毒感染中的应用

Article DOI: 10.3791/59095-v • 06:44 min • January 26th, 2019
January 26th, 2019 •
1, 1, 1
1Department of Pathology and Institute for Human Infections and Immunity, University of Texas Medical Branch

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在 rna 病毒复制过程中产生的双链 rna 可以通过模式识别受体来识别, 从而诱导先天免疫反应。对于负感 rna 病毒, 低水平 dsrna 和 prr 之间的相互作用仍不清楚。我们开发了一种共聚焦显微镜方法, 用于在单个细胞中显示腺病毒 dsrna 和 prr。

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免疫学与感染 第143期 双链 rna 负感 rna 病毒 腺病毒 朱宁病毒 rigi mda-5 模式识别受体 共聚焦显微镜
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