﻿FN Clarivate Analytics Web of Science
VR 1.0
PT J
AU Yu, GR
   Abu Al-Rub, E
   Tao, SX
AF Yu Guorong
   Abu Al-Rub, Emad
   Tao Shengxiang
TI Clinical evaluation of the vacuum sealing drainage (VSD) effect in the
   treatment of severe soft tissue defects of the lower limbs
SO TISSUE ENGINEERING
LA English
DT Meeting Abstract
CT 17th Interdisciplinary Research Conference on Biomaterials
CY APR 02-03, 2007
CL Oxford, ENGLAND
ID THERAPY
C1 Wuhan Univ, Zhongnan Hosp, Dept Orthoped, Wuhan 430072, Peoples R China.
C3 Wuhan University
CR DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
NR 2
TC 1
Z9 1
U1 0
U2 2
PU MARY ANN LIEBERT INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1076-3279
J9 TISSUE ENG
JI Tissue Eng.
PD JUN
PY 2007
VL 13
IS 6
BP 1387
EP 1388
PG 2
WC Cell & Tissue Engineering
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology
GA 178RK
UT WOS:000247237600083
DA 2026-07-24
ER

PT J
AU Patel, A
   Delhougne, G
   Nherera, L
AF Patel, A.
   Delhougne, G.
   Nherera, L.
TI COMPARISON OF WOUND CLOSURE IN SURGICAL WOUNDS BETWEEN SINGLE-USE
   NEGATIVE PRESSURE WOUND THERAPY AND TRADITIONAL NEGATIVE PRESSURE WOUND
   THERAPY: A REAL WORLD ANALYSIS
SO VALUE IN HEALTH
LA English
DT Meeting Abstract
C1 [Patel, A.] Smith & Nephew Inc, Ft Worth, TX USA.
   [Delhougne, G.; Nherera, L.] Smith & Nephew, Ft Worth, TX USA.
C3 Smith & Nephew; Smith & Nephew
NR 0
TC 0
Z9 0
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1098-3015
EI 1524-4733
J9 VALUE HEALTH
JI Value Health
PD MAY
PY 2020
VL 23
SU 1
MA PMD53
BP S199
EP S199
PG 1
WC Economics; Health Care Sciences & Services; Health Policy & Services
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Business & Economics; Health Care Sciences & Services
GA LR6OT
UT WOS:000535812701089
DA 2026-07-24
ER

PT J
AU Gombert, A
AF Gombert, Alexander
TI Is There Enough Evidence for Incisional Negative Pressure Wound Therapy?
SO EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
LA English
DT Editorial Material
DE Groin surgical wound; Incisional negative pressure wound therapy;
   Surgical site infection; Surgical site occurrence; Surgical site
   occurrence
C1 [Gombert, Alexander] Univ Hosp RWTH Aachen, Dept Vasc Surg, Pauwelsstr 30, D-52074 Aachen, Germany.
C3 RWTH Aachen University; RWTH Aachen University Hospital
RP Gombert, A (通讯作者)，Univ Hosp RWTH Aachen, Dept Vasc Surg, Pauwelsstr 30, D-52074 Aachen, Germany.
EM agombert@ukaachen.de
OI Gombert, Alexander/0000-0002-8451-2913
CR Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Gwilym BL, 2021, EUR J VASC ENDOVASC, V61, P636, DOI 10.1016/j.ejvs.2020.11.053
   Lorenzo LR, 2024, EUR J VASC ENDOVASC, V68, P238, DOI 10.1016/j.ejvs.2024.04.031
   Svensson-Björk R, 2019, BJS-BRIT J SURG, V106, P310, DOI 10.1002/bjs.11100
NR 4
TC 0
Z9 0
U1 0
U2 3
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 1078-5884
EI 1532-2165
J9 EUR J VASC ENDOVASC
JI Eur. J. Vasc. Endovasc. Surg.
PD AUG
PY 2024
VL 68
IS 2
BP 245
EP 245
DI 10.1016/j.ejvs.2024.05.013
EA AUG 2024
PG 1
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA C5T0O
UT WOS:001289977700001
PM 38754728
OA Bronze
DA 2026-07-24
ER

PT J
AU Patel, A
   Delhougne, G
   Nherera, L
AF Patel, A.
   Delhougne, G.
   Nherera, L.
TI COMPARISON OF WOUND CLOSURE IN PRESSURE ULCERS BETWEEN SINGLE-USE
   NEGATIVE PRESSURE WOUND THERAPY AND TRADITIONAL NEGATIVE PRESSURE WOUND
   THERAPY: A REAL WORLD ANALYSIS
SO VALUE IN HEALTH
LA English
DT Meeting Abstract
C1 [Patel, A.] Smith & Nephew Inc, Ft Worth, TX USA.
   [Delhougne, G.; Nherera, L.] Smith & Nephew, Ft Worth, TX USA.
C3 Smith & Nephew; Smith & Nephew
NR 0
TC 0
Z9 0
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1098-3015
EI 1524-4733
J9 VALUE HEALTH
JI Value Health
PD MAY
PY 2020
VL 23
SU 1
MA PMD54
BP S199
EP S199
PG 1
WC Economics; Health Care Sciences & Services; Health Policy & Services
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Business & Economics; Health Care Sciences & Services
GA LR6OT
UT WOS:000535812701090
DA 2026-07-24
ER

PT J
AU Rocks, MC
   Wu, M
   Comunale, V
   Agrawal, N
   Nicholas, RS
   Azad, A
   Hacquebord, JH
AF Rocks, Madeline C.
   Wu, Meagan
   Comunale, Victoria
   Agrawal, Nikhil
   Nicholas, Rebecca S.
   Azad, Ali
   Hacquebord, Jacques H.
TI Investigating the Association between Preflap Negative-Pressure Wound
   Therapy and Surgical Outcomes in Extremity Free Flap Reconstruction: A
   Systematic Review
SO JOURNAL OF RECONSTRUCTIVE MICROSURGERY
LA English
DT Review
DE soft tissue reconstruction; extremity trauma; negative-pressure wound
   therapy; systematic review
ID VACUUM-ASSISTED CLOSURE; FREE-TISSUE TRANSFER; LOWER-LIMB INJURY;
   MICROSURGICAL RECONSTRUCTION; FRACTURES; COVERAGE; SUBACUTE; PATIENT;
   TRAUMA
AB Background While prior studies have recommended immediate flap coverage within 72 hours of injury for soft tissue reconstruction for traumatic extremity injuries, recent evidence in the setting of advanced wound care techniques de-emphasizes the need for immediate coverage. Negative-pressure wound therapy (NPWT) has been an essential tool for extending the time to definitive soft tissue coverage. This study sought to elucidate the impact of preoperative NPWT use on the success of microsurgical reconstruction. Methods A literature search was conducted using the following databases from their inception up to February 2023: PubMed, OVID databases (Embase and Cochrane Library), Web of Science, and Scopus. Of 801 identified articles, 648 were assessed and 24 were included. Cases were divided based on whether NPWT was used preoperatively or not. Timing to definitive coverage, injury details, and basic demographics were recorded. Rates of flap failure, infection, bone nonunion, reoperation, and complications were compared between groups. Results A total of 1,027 patients and 1,047 flaps were included, of which 894 (85.39%) received preflap NPWT. The average time to definitive coverage for the NPWT and non-NPWT groups was 16 and 18 days, respectively. The NPWT group experienced lower postoperative complication rates than the non-NPWT group in all reported complications except for deep infections. Compared with the non-NPWT group, the NPWT group experienced lower rates of any flap failure (3.69 vs. 9.80%) and partial flap failure (2.24 vs. 6.54%). Conclusion Preoperative NPWT was associated with reduced postoperative complications, most importantly flap failure rates. This merits further investigation into the decision-making process for traumatic extremity reconstruction. Future prospective studies adopting standardized protocols with longer follow-up are required to better understand the potentially beneficial role of preoperative NPWT use in soft tissue reconstruction.
C1 [Rocks, Madeline C.] George Washington Sch Med & Hlth Sci, Washington, DC USA.
   [Wu, Meagan] Thomas Jefferson Univ, Sidney Kimmel Med Coll, Philadelphia, PA USA.
   [Comunale, Victoria; Nicholas, Rebecca S.; Azad, Ali; Hacquebord, Jacques H.] NYU Langone Hlth, Dept Orthoped Surg, Div Hand Surg, New York, NY USA.
   [Agrawal, Nikhil; Hacquebord, Jacques H.] NYU Langone Hlth, Hansjorg Wyss Dept Plast Surg, New York, NY USA.
C3 George Washington University; Thomas Jefferson University; NYU Langone
   Medical Center; NYU Langone Medical Center
RP Rocks, MC (通讯作者)，George Washington Univ, Sch Med & Hlth Sci, 2300 1St NW, Washington, DC 20052 USA.
EM mrocks@gwu.edu
RI Nicholas, Rebecca/IAM-2265-2023; Agrawal, Nikhil/K-5252-2019
OI Rocks, Madeline/0000-0002-5766-2959; Nicholas,
   Rebecca/0000-0002-9114-7029
CR Aromataris E., 2020, JBI Evid Synth, DOI [10.46658/jbimes-20-08, 10.46658/JBIMES-24-06, DOI 10.46658/JBIMES-20-08, 10.46658/JBIMES-20-08]
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NR 32
TC 4
Z9 4
U1 0
U2 0
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 0743-684X
EI 1098-8947
J9 J RECONSTR MICROSURG
JI J. Reconstr. Microsurg.
PD JUL
PY 2025
VL 41
IS 06
BP 515
EP 520
DI 10.1055/a-2434-5798
EA OCT 2024
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 3LM5A
UT WOS:001345567000001
PM 39362644
DA 2026-07-24
ER

PT J
AU Eisendle, K
   Thuile, T
   Deluca, J
   Pichler, M
AF Eisendle, Klaus
   Thuile, Tobias
   Deluca, Jenny
   Pichler, Maria
TI Surgical Treatment of Pyoderma Gangrenosum with Negative Pressure Wound
   Therapy and Skin Grafting, Including Xenografts: Personal Experience and
   Comprehensive Review on 161 Cases
SO ADVANCES IN WOUND CARE
LA English
DT Review
DE pyoderma gangrenosum; skin graft; negative pressure wound therapy;
   xenotransplant; ustekinumab; infliximab
ID VACUUM-ASSISTED CLOSURE; MYCOPHENOLATE-MOFETIL; BREAST RECONSTRUCTION;
   LEG ULCERS; TNF-ALPHA; REDUCTION MAMMAPLASTY; EFFECTIVE STRATEGIES;
   ULCERATIVE-COLITIS; CLINICAL-FEATURES; HYPERBARIC-OXYGEN
AB Significance: Pyoderma gangrenosum (PG) is a rare debilitating autoinflammatory ulcerative skin disease. No gold standard has been established for the treatment of PG. The role of surgical interventions and negative pressure wound therapy (NPWT) was discussed controversially until recently as these procedures might pose a trigger to further aggravate the condition.
   Recent Advances: Recent advances confirm the paradigm change that a surgical approach of PG with split thickness skin grafting (STSG) secured by NPWT is a safe and valuable treatment if performed under adequate immunosuppression. We elaborate this on the hand of a broad literature search retrieving 101 relevant articles describing 138 patients complemented with our personal experience on 23 patients, including 2 patients treated with a porcine xenodressing.
   Critical Issues: A wide range of surgical approaches have been reported, including xenografts. Treatment was finally successful in 86%, including the xenotransplant cases. Ten percent improved and failures were mainly reported without immunosuppression. Despite halting the inflammatory process, NPWT alone, without skin grafting, does not much accelerate healing time. The best surgical approach appears to be STSG fixed with NPWT as this leads to higher skin graft take. There remains the problem of the chronic nature of PG and the recurrence after tapering of immunosuppression or trauma; therefore, a sustained immunosuppressive treatment is suggested.
   Future Directions: While surgical treatment is supported by the published data, the exact immunosuppression is still evolving. Due to deeper insights into pathogenesis and growing clinical reports, a broader utilization of biologic treatments and a shift from tumor necrosis factor (TNF)-alpha to interleukin (IL)-12/23 or IL-23 antibodies alone are predictable, as IL-12/23 antibodies show good clinical responses with fewer side effects. The positive results with porcine xenodressings might be due to immunological effects of the xenomaterial; they appear promising, but are preliminary and should be confirmed in a larger patient collective.
C1 [Eisendle, Klaus; Thuile, Tobias; Deluca, Jenny; Pichler, Maria] Med Univ Innsbruck, Cent Teaching Hosp Bolzano Bozen, Acad Teaching Dept, Dept Dermatol Venereol & Allergol, Bohlerstr 5, I-39100 Bolzano, Italy.
   [Eisendle, Klaus] Coll Hlth Care Profess, MREST Interdisciplinary Med Res Ctr South Tyrol, Bolzano, Italy.
C3 Krankenhaus Bozen
RP Eisendle, K (通讯作者)，Med Univ Innsbruck, Cent Teaching Hosp Bolzano Bozen, Acad Teaching Dept, Dept Dermatol Venereol & Allergol, Bohlerstr 5, I-39100 Bolzano, Italy.
EM klauseisendle@hotmail.com
RI Eisendle, Klaus/H-6798-2019
OI Eisendle, Klaus/0000-0002-8234-9964
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NR 199
TC 44
Z9 51
U1 0
U2 6
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD JUL 1
PY 2020
VL 9
IS 7
BP 405
EP 425
DI 10.1089/wound.2020.1160
EA APR 2020
PG 21
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA LW9PZ
UT WOS:000529989000001
PM 32320362
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Gupta, S
   Gabriel, A
   Lantis, J
   Teot, L
AF Gupta, Subhas
   Gabriel, Allen
   Lantis, John
   Teot, Luc
TI Clinical recommendations and practical guide for negative pressure wound
   therapy with instillation
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Review
DE Dwell time; Instillation therapy; Negative pressure wound therapy;
   NPWTi-d; Wound healing
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; COST-EFFECTIVENESS;
   RANDOMIZED-TRIAL; MANAGEMENT; IMPACT; RECONSTRUCTION; MULTICENTER;
   EFFICACY; TRAUMA
AB Effective wound management involves a comprehensive assessment of the patient and the wound to determine an optimal wound treatment plan. It is critical to identify and address factors that may impair wound healing, prior to selecting the most appropriate therapy for each patient. Negative pressure wound therapy (NPWT) is a well-established advanced therapy that has been successful in adjunctive management of acute and chronic wounds. In recent years, the introduction of topical wound solution delivery in combination with NPWT has provided further benefits to wound healing. A commercially available system now offers automated, volumetric control of instilled topical wound solutions with a dwell time in combination with NPWT (NPWTi-d; V.A.C. VeraFlo Therapy, KCI, an Acelity company, San Antonio, TX). This NPWTi-d system differs from other instillation systems in that a timed, predetermined volume of topical wound solution is intermittently delivered (versus continuously fed) and allowed to dwell in the wound bed (without NPWT), for a user-selected period of time before NPWT is resumed. This added accuracy and process simplification of solution delivery in tandem with NPWT have prompted use of NPWTi-d as first-line therapy in a wider subset of complex wounds. However, considerably more research is required to validate efficacy of NPWTi-d in various wound types. The purpose of this review is to provide a relevant overview of wound healing, describe current literature supporting the adjunctive use of NPWTi-d, propose a clinical approach for appropriate application of NPWTi-d and conclude with case studies demonstrating successful use of NPWTi-d. Based on this review, we conclude that either a large case series examining effects of NPWTi-d on different wound types or possibly a large prospective registry evaluating NPWTi-d with real-world topical wound solutions versus immediate debridement and closure would be valuable to the medical community in evaluating the efficacy of this promising therapy.
C1 [Gupta, Subhas] Loma Linda Univ, Sch Med, Dept Plast Surg, 11175 Campus Dr,Coleman Pavil 21226, Loma Linda, CA 92354 USA.
   [Gabriel, Allen] PeaceHlth Med Grp Plast Surg, Vancouver, WA USA.
   [Lantis, John] Mt Sinai St Lukes Roosevelt Hosp, Dept Vasc Surg, New York, NY USA.
   [Teot, Luc] Montpellier Univ Hosp, Wound Healing Unit, Montpellier, France.
C3 Loma Linda University; Mount Sinai Morningside; Mount Sinai West;
   Universite de Montpellier; CHU de Montpellier
RP Gupta, S (通讯作者)，Loma Linda Univ, Sch Med, Dept Plast Surg, 11175 Campus Dr,Coleman Pavil 21226, Loma Linda, CA 92354 USA.
EM sgupta@llu.edu
RI Gabriel, Allen/AFK-3548-2022; Gupta, Subhas/C-5458-2018
OI Gupta, Subhas/0000-0001-5091-3922
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NR 62
TC 112
Z9 140
U1 0
U2 19
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2016
VL 13
IS 2
BP 159
EP 174
DI 10.1111/iwj.12452
PG 16
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA DH2UF
UT WOS:000372641400002
PM 26011379
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Steingrimsson, S
   Gottfredsson, M
   Gudmundsdottir, I
   Sjögren, J
   Gudbjartsson, T
AF Steingrimsson, Steinn
   Gottfredsson, Magnus
   Gudmundsdottir, Ingibjorg
   Sjogren, Johan
   Gudbjartsson, Tomas
TI Negative-pressure wound therapy for deep sternal wound infections
   reduces the rate of surgical interventions for early re-infections
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Deep sternal wound infection (DSWI); Mediastinitis; Cardiac surgery;
   Negative-pressure wound therapy; Outcome; Re-infection
ID VACUUM-ASSISTED CLOSURE; POST-STERNOTOMY MEDIASTINITIS; CARDIAC-SURGERY;
   CONVENTIONAL TREATMENT; ICELAND; IMPACT
AB OBJECTIVES: To evaluate the outcome of treatment for deep sternal wound infection (DSWI) in a nationwide patient cohort, before and after the introduction of negative-pressure wound therapy (NPWT).
   METHODS: This was a population-based cohort of all patients treated for DSWI in Iceland out of 2446 open heart operations performed between 2000 and 2010. Length of hospital stay, survival and reoperations were compared in (i) 23 patients treated with open and/or closed irrigation before August 2005 (conventional treatment, CvT group) and in (ii) 20 patients treated after this time with NPWT as a first-line therapy (NPWT group).
   RESULTS: The DSWI rate was 1.8% and did not change during the study period. Demographics were similar for both groups, except for peripheral arterial disease which was less common in the NPWT group. Coagulase-negative staphylococci were also more common (as the only pathogen identified) in the NPWT group (70% vs 30%, P = 0.01). The median length of hospital stay was 43 days in both groups and the sternum could be closed with delayed primary closure in all except 2 patients, one in each group. Eight patients in the CvT group required surgical revision for re-infections, including debridement and rewiring, when compared with 1 patient in the NPWT group (P = 0.02). Furthermore, 6 patients in the CvT group developed late chronic infections of the sternum requiring surgical revision, compared with one in the NPWT group (P = 0.10). The 30-day mortality was not significantly different between groups (4% vs 0%, P > 0.1) and the same was true for 1-year mortality (17% vs 0%, P = 0.11).
   CONCLUSIONS: NPWT significantly reduces the risk of early re-infections in patients with DSWI. There was a lower rate of late chronic sternal infections and lower mortality in the NPWT group, but the difference was not statistically significant. We conclude that NPWT should be considered as a first-line treatment for most DSWIs.
C1 [Steingrimsson, Steinn; Gudbjartsson, Tomas] Landspitali Univ Hosp, Dept Cardiothorac Surg, IS-101 Reykjavik, Iceland.
   [Steingrimsson, Steinn; Gottfredsson, Magnus; Gudbjartsson, Tomas] Univ Iceland, Fac Med, Reykjavik, Iceland.
   [Gottfredsson, Magnus] Landspitali Univ Hosp, Dept Infect Dis, IS-101 Reykjavik, Iceland.
   [Gudmundsdottir, Ingibjorg] Landspitali Univ Hosp, Dept Vasc Surg, IS-101 Reykjavik, Iceland.
   [Sjogren, Johan] Lund Univ, Skane Univ Hosp, Dept Cardiothorac Surg, Lund, Sweden.
C3 Landspitali National University Hospital; University of Iceland;
   Landspitali National University Hospital; Landspitali National
   University Hospital; Lund University; Skane University Hospital
RP Gudbjartsson, T (通讯作者)，Landspitali Univ Hosp, Dept Cardiothorac Surg, IS-101 Reykjavik, Iceland.
EM tomasgud@landspitali.is
RI Steingrimsson, Steinn/AAF-5475-2021; Gottfredsson, Magnus/AAD-9086-2020;
   Sjögren, Johan/AAZ-6448-2021
OI Steingrimsson, Steinn/0000-0001-8320-5607; Gottfredsson,
   Magnus/0000-0003-2465-0422; 
FU Landspitali University Research Foundation
FX This study was supported by grants from the Landspitali University
   Research Foundation.
CR Assmann A, 2011, THORAC CARDIOV SURG, V59, P25, DOI 10.1055/s-0030-1250598
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NR 14
TC 53
Z9 69
U1 1
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD SEP
PY 2012
VL 15
IS 3
BP 406
EP 410
DI 10.1093/icvts/ivs254
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 025GN
UT WOS:000310175900016
PM 22691377
OA Bronze
DA 2026-07-24
ER

PT J
AU Muthu, S
   Viswanathan, VK
   Munisamy, S
   Ponnusamy, DVK
   Theiss, S
   Chandra, SKR
   Sharun, K
   Manoharan, SRR
AF Muthu, Sathish
   Viswanathan, Vibhu Krishnan
   Munisamy, Sathish
   Kolarpatti Ponnusamy, Dhibin Vikash
   Theiss, Steven
   Rajappan Chandra, Sathish Kumar
   Sharun, Khan
   Rajaram Manoharan, Sakthivel Rajan
TI Role of Prophylactic Negative Pressure Wound Therapy in Reducing
   Surgical-Site Infections in Spine Surgery - A Systematic Review and
   Meta-Analysis
SO GLOBAL SPINE JOURNAL
LA English
DT Review; Early Access
DE spine surgery; negative pressure wound therapy; surgical site infection;
   wound complications; prophylactic VAC; cost effectiveness
ID VACUUM-ASSISTED CLOSURE; GUIDELINE; FUSION; DEHISCENCE; PREVENTION;
   MANAGEMENT; RISK
AB Study Design Systematic Review and Meta-analysis. Objective To evaluate the prophylactic efficacy of incisional negative pressure wound therapy(NPWT) in mitigating the postoperative complications following primary spine surgery. Methods A comprehensive search of the databases (PubMed, Embase, Scopus and Web of Science) was performed until October 2025 since inception. Studies comparing incisional NPWT vs standard wound dressing after primary spine surgery were included if at least one of the relevant outcome measures was reported. While the primary endpoint was surgical site infection(SSI), the evaluated secondary outcomes included wound complications, reoperations, readmissions, length of hospital stay(LOS), and cost-effectiveness. Random-effects meta-analysis with Knapp-Hartung adjustment was employed to calculate pooled odds ratios(ORs) and mean differences(MD). The risk of bias assessment was made using the Cochrane ROB2 tool and Newcastle Ottawa Scale. Results Thirteen studies comprising 7619 patients(851NPWT and 6,768controls) were analysed. NPWT significantly mitigated the SSI rates[OR = 0.42, 95%CI(0.28-0.63)P < 0.001;I-2 = 78%) and wound complications[OR = 0.51,95%CI(0.33-0.78)P = 0.03;P = 0.03;I-2 = 0%]. In contrast, reoperation rates[OR = 0.68,95%CI(0.39-1.18)], readmissions[OR = 0.76,95%CI(0.45-1.29)], and LOS [MD = -1.05days,95%CI(-2.16,0.07)] demonstrated non-significant trends, indicating the clinical implications of these secondary outcomes remain uncertain. Two studies reported marked cost savings, with up to $12.9 saved for per $1 spent on NPWT. No significant publication bias was observed. Conclusion Prophylactic incisional NPWT is associated with reduced SSI and wound complications in spine surgery. Given the predominance of retrospective studies, protocol heterogeneity, and limited cost-effectiveness data, these findings should be interpreted cautiously. Current evidence suggests NPWT may be most beneficial in selected high-risk patients, with larger multicentric RCTs needed to confirm routine use and economic value.
C1 [Muthu, Sathish; Viswanathan, Vibhu Krishnan] Dept Spine Surg, Orthopaed Res Grp, Coimbatore 641045, Tamil Nadu, India.
   [Muthu, Sathish] Meenakshi Acad Higher Educ & Res, Meenakshi Med Coll Hosp & Res Inst, Cent Res Lab, Chennai, India.
   [Viswanathan, Vibhu Krishnan; Theiss, Steven; Rajaram Manoharan, Sakthivel Rajan] Univ Alabama Birmingham, Dept Orthoped Surg, Birmingham, AL USA.
   [Munisamy, Sathish] Govt Med Coll, Dept Orthopaed, Namakkal, Tamil Nadu, India.
   [Kolarpatti Ponnusamy, Dhibin Vikash] Govt Med Coll, Dept Orthopaed, Karur, Tamil Nadu, India.
   [Rajappan Chandra, Sathish Kumar] SRM Inst Sci & Technol, Interdisciplinary Inst Indian Syst Med, Clin Trial & Res Unit, Kattankulathur, India.
   [Sharun, Khan] Yuan Ze Univ, Grad Inst Med, Taoyuan, Taiwan.
C3 Meenakshi Academy of Higher Education & Research (MAHER); Meenakshi
   Medical College Hospital & Research Institute; University of Alabama
   System; University of Alabama Birmingham; SRM Institute of Science &
   Technology Chennai; Yuan Ze University
RP Muthu, S (通讯作者)，Dept Spine Surg, Orthopaed Res Grp, Coimbatore 641045, Tamil Nadu, India.
EM drsathishmuthu@gmail.com
RI Muthu, Sathish/G-5756-2018; Sharun, Khan/A-3084-2019; Viswanathan,
   Vibhu/Q-1461-2017
OI Muthu, Sathish/0000-0002-7143-4354; Munisamy,
   Sathish/0009-0009-3417-7772; Sharun, Khan/0000-0003-1040-3746; K P,
   DHIBIN VIKASH/0000-0003-1071-0084
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NR 51
TC 2
Z9 3
U1 0
U2 0
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 2192-5682
EI 2192-5690
J9 GLOB SPINE J
JI Glob. Spine J.
PD 2026 FEB 11
PY 2026
DI 10.1177/21925682261426264
EA FEB 2026
PG 18
WC Clinical Neurology; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Orthopedics
GA DN0KL
UT WOS:001687308800001
PM 41670395
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ma, ZJ
   Shou, KQ
   Li, ZH
   Jian, C
   Qi, BW
   Yu, AX
AF Ma, Zhanjun
   Shou, Kangquan
   Li, Zonghuan
   Jian, Chao
   Qi, Baiwen
   Yu, Aixi
TI Negative pressure wound therapy promotes vessel destabilization and
   maturation at various stages of wound healing and thus influences wound
   prognosis
SO EXPERIMENTAL AND THERAPEUTIC MEDICINE
LA English
DT Article
DE negative pressure wound therapy; pericyte; vessel maturation; wound
   prognosis
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED CONTROLLED-TRIAL; CANCER-PATIENTS;
   GROWTH-FACTORS; IN-VIVO; ANGIOGENESIS; PERICYTES; ANGIOPOIETIN-2;
   EXPRESSION; TISSUE
AB Negative pressure wound therapy (NPWT) has been observed to accelerate the wound healing process in humans through promoting angiogenesis. However, the potential biological effect and relevant molecular mechanisms, including microvessel destabilization, regression and endothelial cell proliferation in the early stage (1-3 days), and the neovascular stabilization and maturation in the later stage (7-15 days), have yet to be fully elucidated. The current study aimed to research the potential effect of NPWT on angiogenesis and vessel maturation, and investigate relevant association between mature microvessels and wound prognosis, as well as the regulatory mechanisms in human wound healing. Patients in the present study (n= 48) were treated with NPWT or a petrolatum gauze, and relevant growth factors and vessel changes were detected using various experimental methods. NPWT increased the expression levels of angiogenin-2 (Ang-2), and decreased the expression levels of Ang-1 and ratios of Ang-1/Ang-2 in the initial stages of wound healing. However, in the latter stages of wound healing, NPWT increased the expression levels of Ang-1 and ratios of Ang-1/Ang-2, as well as the phosphorylation level of tyrosine kinase receptor-2. Consequently, microvessel pericyte coverage was gradually elevated, and the basement membrane was gradually supplied with new blood at the later stage of wound healing. In conclusion, NPWT may preferentially stimulate microvessel destabilization and regression in the early stage of wound healing, and as a consequence, increase angiogenesis. Subsequently, in the later stage of wound healing, NPWT may preferentially promote microvessel stabilization, thereby promoting microvessel maturation in human wounds through the angiogenin/tyrosine kinase receptor-2 signaling pathway. The results of the present study results demonstrated that NPWT was able to accelerate wound healing speed, and thus influence wound prognosis, as a result of an abundance of mature microvessels in human wounds.
C1 [Ma, Zhanjun; Shou, Kangquan; Li, Zonghuan; Jian, Chao; Qi, Baiwen; Yu, Aixi] Wuhan Univ, Dept Orthoped, Zhongnan Hosp, 169 Donghu Rd, Wuhan 430071, Hubei, Peoples R China.
C3 Wuhan University
RP Qi, BW; Yu, AX (通讯作者)，Wuhan Univ, Dept Orthoped, Zhongnan Hosp, 169 Donghu Rd, Wuhan 430071, Hubei, Peoples R China.
EM wb002162@whu.edu.cn; yuaixi@whu.edu.cn
RI /E-6566-2018
FU National Natural Science Foundation of China [81572163]; Hubei National
   Natural Science Fund projects [2014CFB751]
FX The present study was supported by the National Natural Science
   Foundation of China (grant no. 81572163) and by Hubei National Natural
   Science Fund projects (grant no. 2014CFB751). The authors would also
   like to acknowledge the Wuhan VSD Medical Science & Technology, Co.,
   Ltd. (Wuhan, China) for supplying the vacuum material. Finally, thanks
   is given to the Medical Science Experimentation Center of Wuhan
   University for providing the experimental equipment.
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NR 50
TC 41
Z9 55
U1 0
U2 16
PU SPANDIDOS PUBL LTD
PI ATHENS
PA POB 18179, ATHENS, 116 10, GREECE
SN 1792-0981
EI 1792-1015
J9 EXP THER MED
JI Exp. Ther. Med.
PD APR
PY 2016
VL 11
IS 4
BP 1307
EP 1317
DI 10.3892/etm.2016.3083
PG 11
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA DH3TN
UT WOS:000372709800026
PM 27073441
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Borgquist, O
   Ingemansson, R
   Malmsjö, M
AF Borgquist, Ola
   Ingemansson, Richard
   Malmsjo, Malin
TI The Effect of Intermittent and Variable Negative Pressure Wound Therapy
   on Wound Edge Microvascular Blood Flow
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE in vivo; controlled study; negative pressure wound therapy; blood flow;
   pressure levels
ID VACUUM-ASSISTED CLOSURE; MECHANISMS; STRESS
AB Negative pressure wound therapy (NPWT) alters wound edge microvascular blood flow. Some preclinical data suggest that cycling between low and high negative pressure may be more beneficial than continuous NPWT. The purpose of this in vivo study was to compare the effect of intermittent negative pressure (cycled either from 0 to -75 or to -125 mm Hg) and variable negative pressure (cycled from -10 to -75 or -125 mm Hg or from -45 to -75 or -125 mm Hg) on wound edge microvascular blood flow. Using a peripheral wound model (n = 8 domestic 70-kg pigs), intermittent and variable NPWT was applied to surgically created wounds (5 cm diameter, 2 cm. depth) for five cycles of 5 minutes of high and 2 minutes of low pressure. Blood flow was measured using laser Doppler velocimetry in subcutaneous and muscle tissue at 0.5 and 2.5 cm from the wound edge. When NPWT was applied, blood flow decreased an average of 29% +/- 2% in muscle tissue and 22 % +/- 4% in subcutaneous tissue at -75 mm Hg at 0.5 cm from the wound edge and increased an average of 20% +/- 6% for -75 mm Hg at 2.5 cm from the wound edge. Blood flow changed repeatedly when negative pressure was cycled. Large gradients between the cycled pressures (eg, -10 to -75 mm Hg) resulted in greater blood flow alterations than smaller (eg, -45 to -75 mm Hg) gradients. Blood flow alternations were similar between low-pressure settings of -10 mm Hg (variable NPWT) and 0 mm Hg (intermittent NPWT) and between high-pressure settings of -75 or -125 mm Hg. Both intermittent and variable NPWT result in a beneficial combination of increased blood flow, known to facilitate oxygenation and nutrient supply, and decreased blood flow, known to stimulate angiogenesis and granulation tissue formation. Cycling the negative pressure may be especially advantageous when treating poorly vascularized tissue. In cases where intermittent therapy causes patient discomfort, variable therapy may be superior.
C1 [Borgquist, Ola; Malmsjo, Malin] Lund Univ, Dept Ophthalmol, Lund, Sweden.
   [Ingemansson, Richard] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
C3 Lund University; Lund University
RP Malmsjö, M (通讯作者)，A13, S-22184 Lund, Sweden.
EM malin.malmsjo@gmail.com
RI ; Borgquist, Ola/AAO-6451-2020
OI Maljö, Malin/0000-0001-9849-9599; Ingemansson,
   Richard/0000-0001-7623-8953
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 30
TC 52
Z9 61
U1 0
U2 8
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD MAR
PY 2010
VL 56
IS 3
BP 60
EP +
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 576XL
UT WOS:000276183300010
PM 20368675
DA 2026-07-24
ER

PT J
AU Huang, XH
   Zheng, LQ
   Dai, YX
   Hu, SN
   Ning, WC
   Li, SM
   Fan, YG
   Lin, ZL
   Huang, SH
AF Huang, Xiu-Hong
   Zheng, Li-Qin
   Dai, Yue-Xing
   Hu, Shao-Nan
   Ning, Wan-Chen
   Li, Si-Min
   Fan, Yue-Guang
   Lin, Zi-Ling
   Huang, Shao-Hong
TI Combined computational analysis and cytology show limited depth
   osteogenic effect on bone defects in negative pressure wound therapy
SO FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
LA English
DT Article
DE negative pressure wound therapy (NPWT); computational fluid dynamics;
   CFD; bone marrow; bone mesenchymal stem cells (BMSCs); genes sequence;
   bone regeneration
ID MESENCHYMAL STEM-CELLS; VACUUM-ASSISTED CLOSURE; SHEAR-STRESS; MARROW;
   MANAGEMENT; DIFFERENTIATION; FRACTURES; MECHANISM; STIFFNESS; TRAUMA
AB Background: The treatment of bone defects remains a clinical challenge. The effect of negative pressure wound therapy (NPWT) on osteogenesis in bone defects has been recognized; however, bone marrow fluid dynamics under negative pressure (NP) remain unknown. In this study, we aimed to examine the marrow fluid mechanics within trabeculae by computational fluid dynamics (CFD), and to verify osteogenic gene expression, osteogenic differentiation to investigate the osteogenic depth under NP.Methods: The human femoral head is scanned using micro-CT to segment the volume of interest (VOI) trabeculae. The VOI trabeculae CFD model simulating the bone marrow cavity is developed by combining the Hypermesh and ANSYS software. The effect of trabecular anisotropy is investigated, and bone regeneration effects are simulated under NP scales of -80, -120, -160, and -200 mmHg. The working distance (WD) is proposed to describe the suction depth of the NP. Finally, gene sequence analysis, cytological experiments including bone mesenchymal stem cells (BMSCs) proliferation and osteogenic differentiation are conducted after the BMSCs are cultured under the same NP scale.Results: The pressure, shear stress on trabeculae, and marrow fluid velocity decrease exponentially with an increase in WD. The hydromechanics of fluid at any WD inside the marrow cavity can be theoretically quantified. The NP scale significantly affects the fluid properties, especially those fluid close to the NP source; however, the effect of the NP scale become marginal as WD deepens. Anisotropy of trabecular structure coupled with the anisotropic hydrodynamic behavior of bone marrow; An NP of -120 mmHg demonstrates the majority of bone formation-related genes, as well as the most effective proliferation and osteogenic differentiation of BMSCs compared to the other NP scales.Conclusion: An NP of -120 mmHg may have the optimal activated ability to promote osteogenesis, but the effective WD may be limited to a certain depth. These findings help improve the understanding of fluid mechanisms behind NPWT in treating bone defects.
C1 [Huang, Xiu-Hong; Hu, Shao-Nan; Ning, Wan-Chen; Li, Si-Min; Huang, Shao-Hong] Southern Med Univ, Stomatol Hosp, Sch Stomatol, Guangzhou, Peoples R China.
   [Zheng, Li-Qin; Dai, Yue-Xing] Guangzhou Univ Chinese Med, Clin Med Coll 1, Guangzhou, Peoples R China.
   [Fan, Yue-Guang] Guangzhou Univ Chinese Med, Affiliated Hosp 1, Dept Joint Surg, Guangzhou, Peoples R China.
   [Lin, Zi-Ling] Guangzhou Univ Chinese Med, Affiliated Hosp 1, Dept Orthoped Trauma, Guangzhou, Peoples R China.
C3 Southern Medical University - China; Guangzhou University of Chinese
   Medicine; Guangzhou University of Chinese Medicine; Guangzhou University
   of Chinese Medicine
RP Huang, SH (通讯作者)，Southern Med Univ, Stomatol Hosp, Sch Stomatol, Guangzhou, Peoples R China.; Lin, ZL (通讯作者)，Guangzhou Univ Chinese Med, Affiliated Hosp 1, Dept Orthoped Trauma, Guangzhou, Peoples R China.
EM 13600460045@sina.cn; hsh.china@tom.com
RI ; Ning, Wanchen/AAW-8866-2021; /Q-1923-2015; 胡, 少南/CAH-9613-2022
OI Zheng, Liqin/0000-0002-8157-5433; Ning, Wanchen/0000-0003-1075-997X;
   huang, xiuhong/0000-0002-8788-3314; 
FU Science Research Cultivation Program of Stomatological Hospital,
   Southern Medical University [PY2022004]; National Famous Old Chinese
   Medicine Expert Inheritance Studio Construction Project; National
   Natural Science Foundation of China [81673996]
FX Science Research Cultivation Program of Stomatological Hospital,
   Southern Medical University (PY2022004); National Famous Old Chinese
   Medicine Expert Inheritance Studio Construction Project (2022); National
   Natural Science Foundation of China (81673996).
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NR 60
TC 2
Z9 2
U1 2
U2 18
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-4185
J9 FRONT BIOENG BIOTECH
JI Front. Bioeng. Biotechnol.
PD FEB 16
PY 2023
VL 11
AR 1056707
DI 10.3389/fbioe.2023.1056707
PG 18
WC Biotechnology & Applied Microbiology; Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biotechnology & Applied Microbiology; Engineering
GA 9M8MT
UT WOS:000942477400001
PM 36873351
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Misticoni, F
   Chiavaroli, V
   Cauzzo, C
   Fornaro, DS
   Miscia, ME
   Fusillo, M
   Lisi, G
   Chiarelli, F
   Di Valerio, S
AF Misticoni, Francesco
   Chiavaroli, Valentina
   Cauzzo, Chiara
   Fornaro, Davide Scarponcini
   Miscia, Maria Enrica
   Fusillo, Mario
   Lisi, Gabriele
   Chiarelli, Francesco
   Di Valerio, Susanna
TI Case Report: Staged surgical repair and negative pressure wound therapy
   in congenital omphalocele
SO FRONTIERS IN PEDIATRICS
LA English
DT Article
DE congenital disorders; negative pressure wound therapy; newborn;
   omphalocele; surgical procedures
ID VACUUM-ASSISTED CLOSURE; GIANT OMPHALOCELES; MANAGEMENT; EXOMPHALOS
AB Background Omphalocele is a congenital abdominal wall defect that causes the protrusion of the abdominal organs at the base of the umbilical cord, which is covered by a membranous sac composed of the peritoneum and amnion. We report the case of a newborn with a giant omphalocele containing the liver and bowel loops who underwent staged surgical closure followed by negative pressure wound therapy (NPWT) for the management of skin wound dehiscence.Case presentation A male Caucasian infant was born at 35 weeks by elective cesarean section due to a prenatal diagnosis of a giant omphalocele. The clinical examination at birth confirmed a giant omphalocele with extensive liver and small bowel content. Cardio-respiratory and neurological examinations were unremarkable. The omphalocele was initially wrapped with hydrocolloid dressings. After bowel content reduction and epithelialization of the membrane, a three-stage surgery was scheduled as follows: first, a silo bag was fashioned (on day 22); then, after complete liver reduction, the wide muscle-fascial defect was temporarily covered by a porcine dermal implant to close the gap (on day 32); finally, the abdominal wall was fully closed without prosthetic material using the component separation method (on day 68). NPWT was performed in two stages for a total of 29 days. The first period, applied between the second and third interventions, began on day 37 and continued for 16 days. Due to partial dehiscence of the surgical wound, NPWT was restarted on day 75 for 13 days, with increasing pressure (from -20 to -40 mmHg). Progressive improvement of the wound was obtained. After NPWT removal, an antimicrobial hydro-balanced dressing was placed on the wound.Conclusions This case underlines the lack of a standardized therapeutic approach for complex abdominal wall defects. It also highlights the efficacy of NPWT in complicated surgical wounds in infancy, given the reduction in dressing frequency and related stress. Furthermore, NPWT guarantees a significant reduction in the number of days required for the resolution of the surgical wound.
C1 [Misticoni, Francesco] G Dannunzio Univ Chieti & Pescara, Dept Pediat, Chieti, Italy.
   [Chiavaroli, Valentina; Cauzzo, Chiara; Fornaro, Davide Scarponcini; Di Valerio, Susanna] Santo Spirito Hosp, Neonatal Intens Care Unit, Pescara, Italy.
   [Miscia, Maria Enrica; Fusillo, Mario; Lisi, Gabriele] Santo Spirito Hosp, Pediat Surg Unit, Pescara, Italy.
   [Lisi, Gabriele; Chiarelli, Francesco] G Dannunzio Univ Chieti & Pescara, Dept Med & Aging Sci, Chieti, Italy.
C3 G d'Annunzio University of Chieti-Pescara; G d'Annunzio University of
   Chieti-Pescara
RP Chiavaroli, V (通讯作者)，Santo Spirito Hosp, Neonatal Intens Care Unit, Pescara, Italy.
EM valentina.chiavaroli@asl.pe.it
RI Chiavaroli, Valentina/ABB-1911-2020
FU Lohmann & Rauscher GmbH Co.
FX The author(s) declared that financial support was received for this work
   and/or its publication. The Article Processing Charge (APC) was funded
   by Lohmann & Rauscher GmbH & Co. KG. The funder had no role in study
   design, data collection, analysis, interpretation of data, writing of
   the manuscript, or decision to publish.
CR Abello C, 2021, J PEDIATR SURG, V56, P1068, DOI 10.1016/j.jpedsurg.2020.12.003
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NR 21
TC 0
Z9 0
U1 0
U2 0
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-2360
J9 FRONT PEDIATR
JI Front. Pediatr.
PD MAR 18
PY 2026
VL 14
AR 1771958
DI 10.3389/fped.2026.1771958
PG 7
WC Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics
GA GA3ZK
UT WOS:001731693600001
PM 41929918
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Isaac, DL
AF Isaac, Dona Lyndhia
TI Complex Wound Management Using Negative Pressure Wound Therapy With
   Instillation and Dwell Time in a Cancer Care Setting
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article; Proceedings Paper
CT Spring Symposium on Advanced Wound Care (SAWC)
CY MAY 07-11, 2019
CL San Antonio, TX
DE negative pressure wound therapy with instillation and dwell time;
   cancer; cancer-related wounds; complex wound; NPWTi-d
ID VACUUM-ASSISTED CLOSURE; INGUINAL LYMPHADENECTOMY; PENILE CANCER;
   COMPLICATIONS; ULCERS
AB Introduction. Unresolved wound healing represents a major health care cost with a negative impact on patient quality of life, especially among oncology patients who exhibit a delay in the wound healing cascade due to chemotherapy and radiation. In order to address this problem, the author utilized negative pressure wound therapy (NPWT) with instillation and dwell time (NPWTi-d) to cleanse wounds of debris and help promote healing. Objective. The author examines the impact of NPWTi-d on multiple indicators of wound healing progress in 6 cancer patients with complex wounds and multiple comorbidities. Materials and Methods. The NPWTi-d was initiated with instillation of normal saline or 0.125% hypochlorite solution, which was allowed to dwell for 3 to 20 minutes, followed by 2 to 3.5 hours of -125 mm Hg continuous negative pressure. Dressing changes were performed every 2 to 3 days. Debridements, incision and drainage, and antibiotics were administered as necessary. Results. A total of 1 woman and 5 men (average age, 62 years; range, 53-78 years) presented with the following wounds: surgical dehiscence (n = 3), pressure injury (n = 1), chronic seroma (n = 1), and abdominal wall abscess (n = 1). Malignancy was not detectable in any wounds. Patient comorbidities included diabetes, hypertension, and past treatment for cancers. The NPWTi-d was applied for 1 to 2 weeks, after which the wounds exhibited a reduction in slough, an improvement in granulation tissue, and a decrease in wound volume. Wounds were closed with a flap or transitioned to conventional NPWT prior to discharge home or to a rehabilitation facility for outpatient recovery. Conclusions. As shown in this case series, NPWTi-d was a beneficial tool for cleansing the wound bed, thus creating a moist, closed wound environment conducive to healing. Using NPWTi-d supported the formation of a healthy wound bed and contributed to rapid, positive outcomes in this patient population.
C1 [Isaac, Dona Lyndhia] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA.
C3 Memorial Sloan Kettering Cancer Center
RP Isaac, DL (通讯作者)，Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA.
EM isaacd@mskcc.org
FU NCI NIH HHS [P30 CA008748] Funding Source: Medline
CR Althumairi AA, 2016, WORLD J SURG, V40, P1755, DOI 10.1007/s00268-016-3450-0
   Bach CA, 2016, HEAD NECK-J SCI SPEC, V38, P696, DOI 10.1002/hed.23952
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NR 19
TC 4
Z9 4
U1 0
U2 6
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD MAY
PY 2020
VL 32
IS 5
BP 118
EP 122
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Dermatology; Surgery
GA PQ8GI
UT WOS:000606781600001
PM 32804665
DA 2026-07-24
ER

PT J
AU Haspeslagh, M
   Van Hecke, LL
   Hermans, K
   Chiers, K
   Pint, E
   Wilmink, JM
   Martens, AM
AF Haspeslagh, Maarten
   Van Hecke, Lore L.
   Hermans, Katleen
   Chiers, Koen
   Pint, Eva
   Wilmink, Jacintha M.
   Martens, Ann M.
TI Limited added value of negative pressure wound therapy compared with
   calcium alginate dressings for second intention healing in a
   noncontaminated and contaminated equine distal limb wound model
SO EQUINE VETERINARY JOURNAL
LA English
DT Article
DE calcium alginate dressing; horse; horse wound healing; in vivo wound
   model; negative pressure wound therapy
ID VACUUM-ASSISTED CLOSURE; BACTERIAL LOAD; MANUKA HONEY; MANAGEMENT
AB Background Distal limb wounds in horses often show aberrant healing due to a slow inflammatory response. In human medicine, negative pressure wound therapy (NPWT) is used for the treatment of chronic wounds with a similar inflammatory response. Objectives To compare the effect of NPWT to calcium alginate dressings on the healing of (non) contaminated equine distal limb wounds. Study design Controlled experiment. Methods Circular wounds were created on the left and right dorsomedial metacarpus of 10 horses. In five horses, the wounds were contaminated with Staphylococcus aureus and Pseudomonas aeruginosa. In all horses, one limb was treated with NPWT, the other with calcium alginate dressings. Treatments were applied during nine days for noncontaminated wounds and six days for contaminated wounds. Noninvasive (clinical assessment, bacteriology swabs, thermographic images and wound dimensions) and invasive (biopsies for histology and growth factor analysis) measurements were taken regularly for 71 and 29 days respectively. Effects of selected parameters on continuous dependent variables were analysed using ANOVA, while for discrete dependent variables, logistic regression was applied. Results In noncontaminated wounds, there was significantly less wound retraction in the early healing stages when treated with NPWT (mean difference [95% CI] = 19.2% [13.3%-25.1%]; P = .005), although wound size was not significantly different between NPWT and control wounds at later healing stages. Noncontaminated control wounds had a significantly higher neutrophil influx (OR [95% CI] = 1.99 [1.49-2.66]; P < .001) and lower macrophage influx (OR [95% CI] = 0.75 [0.60-0.93]; P = .008) compared with NPWT-treated wounds. Bacterial load and the presence of growth factors did not differ between treatments in noncontaminated wounds. In contaminated wounds, no differences between treatments were observed in wound size, histological parameters, bacterial load or growth factor concentration. Main limitations Sample size is small. Conclusions No long-term advantage was detected with NPWT compared with calcium alginate dressings in noncontaminated or contaminated equine distal limb wounds healing by second intention.
C1 [Haspeslagh, Maarten; Van Hecke, Lore L.; Pint, Eva; Martens, Ann M.] Univ Ghent, Fac Vet Med, Dept Surg & Anaesthesiol Domest Anim, Merelbeke, Belgium.
   [Hermans, Katleen; Chiers, Koen] Univ Ghent, Fac Vet Med, Dept Pathol Bacteriol & Poultry Dis, Merelbeke, Belgium.
   [Wilmink, Jacintha M.] Woumarec, Wageningen, Netherlands.
   [Van Hecke, Lore L.] Global Stem Cell Technol, Noorwegenstr 4, B-9940 Evergem, Belgium.
C3 Ghent University; Ghent University
RP Haspeslagh, M (通讯作者)，Univ Ghent, Fac Vet Med, Dept Surg & Anaesthesiol Domest Anim, Merelbeke, Belgium.
EM maarten.haspeslagh@ugent.be
RI Haspeslagh, Maarten/T-8618-2019; Chiers, Koen/NJS-8348-2025
OI Martens, Ann/0000-0001-9554-4841; Chiers, Koen/0000-0002-7449-1047
FU Special Research Fund, Ghent University [01D25512]
FX Special Research Fund, Ghent University, grant no 01D25512.
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NR 25
TC 7
Z9 10
U1 2
U2 21
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0425-1644
EI 2042-3306
J9 EQUINE VET J
JI Equine Vet. J.
PD MAY
PY 2022
VL 54
IS 3
BP 592
EP 600
DI 10.1111/evj.13487
EA JUL 2021
PG 9
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA 0J3SC
UT WOS:000678797500001
PM 34115409
DA 2026-07-24
ER

PT J
AU Malmsjö, M
   Lindstedt, S
   Ingemansson, R
AF Malmsjo, Malin
   Lindstedt, Sandra
   Ingemansson, Richard
TI Influence on pressure transduction when using different drainage
   techniques and wound fillers (foam and gauze) for negative pressure
   wound therapy
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Animal model; Experimental surgery; Negative pressure wound therapy;
   Pressure transduction; Sternotomy wound; Wound fluid drainage; Wound
   healing
ID VACUUM-ASSISTED CLOSURE; FOUNDATION
AB Pressure transduction to the wound bed in negative pressure wound therapy (NPWT) is crucial in stimulating the biological effects ultimately resulting in wound healing. In clinical practice, either foam or gauze is used as wound filler. Furthermore, two different drainage techniques are frequently employed. One involves the connection of a non-perforated drainage tube to the top of the dressing, while the other involves the insertion of perforated drains into the dressing. The aim of this study was to examine the efficacy of these two different wound fillers and drainage systems on pressure transduction to the wound bed in a challenging wound (the sternotomy wound). Six pigs underwent median sternotomy. The wound was sealed for NPWT using different wound fillers (foam or gauze) and drainage techniques (see earlier). Pressures between 0 and -175 mmHg were applied and the pressure in the wound was measured using saline-filled catheters sutured to the bottom of the wound (over the anterior surface of the heart) and to the side of the wound (on the thoracic wall). The negative pressure on the wound bed increased linearly with the negative pressure delivered by the vacuum source. In a dry wound, the pressure transduction was similar when using the different wound fillers (foam and gauze) and drainage techniques. In a wet wound, pressure transduction was better when using a perforated drainage tube inserted into the wound filler than a non-perforated drainage tube connected to the top of the dressing (-116 +/- 1 versus -73 +/- 4 mmHg in the wound at a delivered pressure of -125 mmHg for foam, P < 0.01), regardless of the type of wound filler. Gauze and foam are equally effective at delivering negative pressure to the wound bed. Perforated drainage tubes inserted into the wound filler are more efficient than a non-perforated drainage tubes connected to the top of the dressing. The choice of drainage technique may be particularly important in wounds with a large volume of exudate.
C1 [Malmsjo, Malin] Lund Univ, Dept Ophthalmol, Lund, Sweden.
   [Malmsjo, Malin; Lindstedt, Sandra; Ingemansson, Richard] Skane Univ Hosp, Lund, Sweden.
   [Lindstedt, Sandra; Ingemansson, Richard] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
C3 Lund University; Lund University; Skane University Hospital; Lund
   University
RP Malmsjö, M (通讯作者)，BMC A13, SE-22184 Lund, Sweden.
EM malin.malmsjo@med.lu.se
RI ; Lindstedt, Sandra/AEM-2892-2022
OI Maljö, Malin/0000-0001-9849-9599; Ingemansson,
   Richard/0000-0001-7623-8953; Lindstedt, Sandra/0000-0003-4484-6473
FU Ake-Wieberg Foundation; Magn Bergvall Foundation; Swedish Medical
   Association; Royal Physiographic Society in Lund; Crafoord Foundation;
   Swedish Heart-Lung Foundation; Swedish Hypertension Society; Smith &
   Nephew Wound Management
FX This study was funded by the Ake-Wieberg Foundation, the Magn Bergvall
   Foundation, the Swedish Medical Association, the Royal Physiographic
   Society in Lund, the Crafoord Foundation, the Swedish Heart-Lung
   Foundation, the Swedish Hypertension Society and Smith & Nephew Wound
   Management. We thank Robin Martin (Smith & Nephew) for review of the
   manuscript.
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NR 13
TC 17
Z9 23
U1 0
U2 11
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1742-4801
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2010
VL 7
IS 5
BP 406
EP 412
DI 10.1111/j.1742-481X.2010.00706.x
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 723NU
UT WOS:000287514300012
PM 20649833
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Wang, N
   Li, SS
   Liu, YP
   Peng, YY
   Wang, PF
AF Wang, Nan
   Li, Shuang-Shuang
   Liu, Ya-Ping
   Peng, Ying-Ying
   Wang, Peng-Fei
TI Comparison of negative pressure wound therapy and moist wound care in
   patients with diabetic foot ulcers: A protocol for systematic review and
   meta-analysis of randomized controlled trials
SO MEDICINE
LA English
DT Review
DE diabetic foot ulcer; meta-analysis; moist wound care; negative pressure
   wound therapy
ID VACUUM-ASSISTED CLOSURE; MULTICENTER; PREVALENCE; MELLITUS
AB Background: This study conducted a meta-analysis to compare the effectiveness and safety of the negative pressure wound therapy (NPWT) with the moist wound care (MWC) in the treatment of diabetic foot ulcers (DFUs). Methods: The PubMed, EMBASE, and CENTRAL were searched by 2 of the authors, to identify randomized controlled trials comparing the clinical outcomes of patients treated with NPWT versus MWC for DFUs. Meta-analyses were performed for several outcomes, including wound healing results, amputation or resection incidence, and risk of adverse events, utilizing the "meta" package of R language version 4.0.3. Results: A total of 10 trials (619 patients in NPWT group and 625 in MWC group) and 8 trials were included for the qualitative and quantitative syntheses, respectively. As a result, significantly lower risk of non-closure of the wound (risk ratio [RR] = 0.74, 95% confidence interval [CI]: 0.63-0.87; P = .001), lower average wound area (standard mean difference = -0.80, 95% CI: -1.54 to -0.06; P = .034), more wound area decrease (standard mean difference = 0.81, 95% CI: 0.36-1.26; P = .001), increased appearance rate of granulation tissue (RR = 1.61, 95% CI: 1.07-2.41; P-0.021), and lower risk of amputation or resection (RR = 0.70, 95% CI: 0.50-0.99; P = .045), were demonstrated for the NPWT group when compared to MWC group. However, no statistically significant difference was found for the disappearance rate of wound discharge at 8 weeks, the rate of blood culture positivity, VAS-pain score, and the overall frequency of adverse events between the 2 treatment groups (P = .05). Conclusion: NPWT could accelerate process of the wound healing, and decrease the risk of post-treatment amputation or resection, without any additional frequency of adverse events, when compared with MWC, in patients with DFUs.
C1 [Wang, Nan; Li, Shuang-Shuang; Liu, Ya-Ping; Peng, Ying-Ying; Wang, Peng-Fei] Cangzhou Cent Hosp, 16 Xinhua Western Rd, Cangzhou City 061000, Hebei, Peoples R China.
RP Wang, PF (通讯作者)，Cangzhou Cent Hosp, 16 Xinhua Western Rd, Cangzhou City 061000, Hebei, Peoples R China.
EM wangpengfei112233@yeah.net; lishuangshuang2021@163.com;
   liuyapingcangzhou@yeah.net; pengyingyingpyy@163.com;
   wangpengfei112233@yeah.net
RI Wang, Pengfei/AAN-8797-2020
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NR 23
TC 3
Z9 6
U1 0
U2 18
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD AUG 5
PY 2022
VL 101
IS 31
AR e29537
DI 10.1097/MD.0000000000029537
PG 8
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 3P8IJ
UT WOS:000837777500008
PM 35945751
OA Green Published, gold
DA 2026-07-24
ER

PT J
AU Zuo, J
   Zhu, Y
   Yang, F
   Yang, Y
   Yang, JT
   Huang, ZL
   Cheng, B
AF Zuo, Jun
   Zhu, Yi
   Yang, Feng
   Yang, Yong
   Yang, Juntao
   Huang, Ze Lin
   Cheng, Biao
TI Polyurethane foam dressing with non-adherent membrane improves negative
   pressure wound therapy in pigs
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE blood perfusion; negative pressure wound therapy; non-adherent membrane;
   polyurethane dressing; polyvinyl alcohol dressing; wound; wound care;
   wound dressing; wound healing
ID VACUUM-ASSISTED CLOSURE; MICROVASCULAR BLOOD-FLOW; CONTRACTION; GRAFTS;
   DEVICE; STATE
AB Objective: Negative pressure wound therapy (NPWT) is considered to be an effective technique to promote the healing of various wounds. The aim of this study was to evaluate different wound dressings combined with NPWT in treating wounds in Wuzhishan pigs. Method: Excisions were made in the backs of the pigs and were covered with polyvinyl alcohol (PVA) dressing, polyurethane (PU) dressing or PU dressing with non -adherent membrane (PU-non-ad). NPWT was applied to the wound site. In the control group, basic occlusive dressing (gauze) without NPWT was applied. On days 0, 3, 7, 14, 21 and 28 post -surgery, the wound size was measured during dressing change, and wound healing rate (WHR) was calculated. In addition, blood perfusion within 2cm of the surrounding wound was measured by laser doppler flowmetry. Dressing specimen was collected and microbiology was analysed. Granulation tissues from the central part of the wounds were analysed for histology, vascular endothelial growth factor (VEGF) and cluster of differentiation 31 (CD31) mRNA expression. Results: The PU-non-ad-NPWT significantly (p<0.01) accelerated wound healing in the pigs. Further pathological analysis revealed that the non -adherent membrane effectively protected granulation tissue formation in PU-NPWT treated wounds. The blood perfusion analysis suggested that the non -adherent membrane improved the blood supply to the wound area. Microbiological analysis showed that non -adherent membrane decreased the bacterial load in the PU-NPWT dressing. VEGF and CD31 mRNA expression was upregulated in the wound tissue from the PU-non-ad-NPWT treated groups. Conclusion: In this study, the PU dressing with non -adherent membrane was an ideal dressing in NPWT-assisted wound healing. Declaration of interest: This work was supported by the Science and Technology Plan Project of Guangdong province in China (2015B020233012) and the Youth Science Fund Project of Natural Science Foundation of Hunan Province in China (2021JJ40487).
C1 [Zuo, Jun] Southern Med Univ, Sch Clin Med 1, Guangzhou 510000, Peoples R China.
   [Zuo, Jun; Zhu, Yi; Yang, Feng; Yang, Yong; Yang, Juntao; Huang, Ze Lin] Univ South China, Affiliated Hosp 2, Hengyang 421000, Peoples R China.
   [Cheng, Biao] PLA, Gen Hosp Southern Theater Command, Dept Burn & Plast Surg, Guangzhou 510000, Peoples R China.
C3 Southern Medical University - China; University of South China; Southern
   Theater Command General Hospital
RP Cheng, B (通讯作者)，PLA, Gen Hosp Southern Theater Command, Dept Burn & Plast Surg, Guangzhou 510000, Peoples R China.
EM chengbiaocheng@163.com
CR Anesäter E, 2011, INT WOUND J, V8, P336, DOI 10.1111/j.1742-481X.2011.00790.x
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NR 34
TC 0
Z9 0
U1 0
U2 5
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD FEB
PY 2024
VL 33
SU 2A
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA LN3E9
UT WOS:001187436200002
DA 2026-07-24
ER

PT J
AU Rodriguez-Unda, N
   Soares, KC
   Azoury, SC
   Baltodano, PA
   Hicks, CW
   Burce, KK
   Cornell, P
   Cooney, CM
   Eckhauser, FE
AF Rodriguez-Unda, Nelson
   Soares, Kevin C.
   Azoury, Said C.
   Baltodano, Pablo A.
   Hicks, Caitlin W.
   Burce, Karen K.
   Cornell, Peter
   Cooney, Carisa M.
   Eckhauser, Frederic E.
TI Negative-Pressure Wound Therapy in the Management of High-Grade Ventral
   Hernia Repairs
SO JOURNAL OF GASTROINTESTINAL SURGERY
LA English
DT Article
DE Ventral hernia; Vacuum-assisted closure; Negative pressure wound
   therapy; Grade 3 hernia; abdominal wall reconstruction; Surgical site
   infection
ID ACELLULAR DERMAL MATRIX; ABDOMINAL-WALL DEFECTS; HIGH-RISK; INCISIONAL
   HERNIA; UMBILICAL HERNIA; SYNTHETIC MESH; POLYPROPYLENE MESH; OUTCOMES;
   RECONSTRUCTION; RECURRENCE
AB Despite improved operative techniques, open ventral hernia repair (VHR) surgery in high-risk, potentially contaminated patients remains challenging. As previously reported by our group, the use of a modified negative-pressure wound therapy system (hybrid-VAC or HVAC) in patients with grade 2 hernias is associated with lower surgical site occurrence (SSO) and surgical site infection (SSI) rates. Accordingly, the authors aim to evaluate whether the HVAC would similarly improve surgical site outcomes following VHR in patients with grade 3 hernias.
   A 4-year retrospective review (2011-2014) was conducted of all consecutive, modified ventral hernia working group (VHWG) grade 3 hernia repairs with HVAC closure performed by a single surgeon (FEE) at a single institution. Operative data and 90-day outcomes were evaluated. Overall outcomes (e.g., recurrence, reoperation, mortality) were reviewed for the study group.
   A total of 117 patients with an average age of 56.7 +/- 11.9 years were classified as grade 3 hernias and underwent open VHR with subsequent HVAC closure. Fifty patients were male (42.7 %), the mean BMI was 35.2 (+/- 9.5), and 60.7 % had a history of prior hernia repair. The average fascial defect size was 201.5 (+/- 167.3) cm(2) and the mean length of stay was 14.2 (+/- 9.3) days. Ninety-day outcomes showed an SSO rate of 20.7 % and an SSI rate of 5.2 %. The overall hernia recurrence rate was 4.2 % (n=6) with a mean follow-up of 11 +/- 7.3 months.
   Modified VHWG grade 3 ventral hernias are associated with significant morbidity. In our series utilizing the HVAC system after VHR, the observed rate of SSO and SSI compared favorably to reported series. Further prospective cost-effective studies are warranted to validate these findings.
C1 [Rodriguez-Unda, Nelson; Soares, Kevin C.; Azoury, Said C.; Baltodano, Pablo A.; Hicks, Caitlin W.; Burce, Karen K.; Cornell, Peter; Cooney, Carisa M.; Eckhauser, Frederic E.] Johns Hopkins Univ, Sch Med, Dept Surg, Baltimore, MD 21287 USA.
C3 Johns Hopkins University
RP Eckhauser, FE (通讯作者)，Johns Hopkins Univ, Sch Med, Dept Surg, Blalock 618,600 N Wolfe St, Baltimore, MD 21287 USA.
EM feckhau2@jhmi.edu
RI Hicks, Caitlin/JAX-4080-2023; Soares, Kevin/PII-7807-2026
OI Hicks, Caitlin/0000-0001-7638-1936; 
FU KCI(R)
FX This study was made possible in part through an investigator initiated
   trial grant from KCI (R).
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NR 45
TC 13
Z9 13
U1 0
U2 8
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1091-255X
EI 1873-4626
J9 J GASTROINTEST SURG
JI J. Gastrointest. Surg.
PD NOV
PY 2015
VL 19
IS 11
BP 2054
EP 2061
DI 10.1007/s11605-015-2894-0
PG 8
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA CV0YH
UT WOS:000363979300016
PM 26239514
DA 2026-07-24
ER

PT J
AU Vig, S
   Dowsett, C
   Berg, L
   Caravaggi, C
   Rome, P
   Birke-Sorensen, H
   Bruhin, A
   Chariker, M
   Depoorter, M
   Dunn, R
   Duteille, F
   Ferreira, F
   Martínez, JMF
   Grudzien, G
   Hudson, D
   Ichioka, S
   Ingemansson, R
   Jeffery, S
   Krug, E
   Lee, C
   Malmsjo, M
   Runkel, N
   Martin, R
   Smith, J
AF Vig, S.
   Dowsett, C.
   Berg, L.
   Caravaggi, C.
   Rome, P.
   Birke-Sorensen, H.
   Bruhin, A.
   Chariker, M.
   Depoorter, M.
   Dunn, R.
   Duteille, F.
   Ferreira, F.
   Francos Martinez, J. M.
   Grudzien, G.
   Hudson, D.
   Ichioka, S.
   Ingemansson, R.
   Jeffery, S.
   Krug, E.
   Lee, C.
   Malmsjo, M.
   Runkel, N.
   Martin, R.
   Smith, J.
CA Int Expert Panel Negative Pressure
TI Evidence-based recommendations for the use of negative pressure wound
   therapy in chronic wounds: Steps towards an international consensus
SO JOURNAL OF TISSUE VIABILITY
LA English
DT Review
DE Negative Pressure Wound Therapy (NPWT); Consensus; Recommendations;
   Systematic review; Chronic wounds; Pressure ulcers; Diabetic foot
   ulcers; Ischaemic ulcers
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; RANDOMIZED
   CONTROLLED-TRIAL; CHRONIC LEG ULCER; CLINICAL-APPLICATIONS; LIMB
   ISCHEMIA; SKIN-GRAFTS; AMPUTATION; MULTICENTER; EXPERIENCE
AB Aim: Negative Pressure Wound Therapy (NPWT) has become widely adopted over the last 15 years and over 1000 peer-reviewed publications are available describing its use. Despite this, there remains uncertainty regarding several aspects of usage. In order to respond to this gap a global expert panel was convened to develop evidence-based recommendations describing the use of NPWT. In this communication the results of the study of evidence in chronic wounds including pressure ulcers, diabetic foot ulcers (DFU), venous leg ulcers (VLU), and ischaemic lower limb wounds are reported.
   Methods: Evidence-based recommendations were obtained by a systematic review of the literature, grading of evidence, drafting of the recommendations by a global expert panel followed by a formal consultative consensus development program in which 422 independent healthcare professionals were able to agree or disagree with the recommendations. The criteria for agreement were set at 80% agreement. Evidence and recommendations were graded according to the SIGN (Scottish Intercollegiate Guidelines Network) classification system.
   Results: The primary treatment goal of NPWT in most chronic wounds is to achieve wound closure (either by secondary intention or preparing the wound for surgical closure). Secondary goals commonly include: to reduce wound dimensions, and to improve the quality of the wound bed. Thirteen evidence based recommendations were developed in total to address these treatment goals; 4 for pressure ulcers, 4 for DFU, 3 for ischaemic lower limb wounds and 2 for VLU.
   Conclusion: The present evidence base is strongest for the use of NPWT in non-ischaemic DFU and weakest in VLU. The development of evidence-based recommendations for NPWT with direct validation from a large group of practicing clinicians offers a broader basis for consensus than work by an expert panel alone. (c) 2011 Published by Elsevier Ltd on behalf of Tissue Viability Society.
C1 [Vig, S.] Croydon Univ Hosp, London, England.
   [Dowsett, C.] E London NHS Fdn Trust, Community Hlth Newham Directorate, London, England.
   [Berg, L.] Kuopio Univ Hosp, Kuopio, Finland.
   [Caravaggi, C.] Ctr Treatment Diabet Foot Pathol, Ist Clin Citta Studi, Milan, Italy.
   [Rome, P.] Royal Prince Alfred Hosp, Sydney, NSW, Australia.
   [Rome, P.] Concord Hosp, Sydney, NSW, Australia.
   [Birke-Sorensen, H.] Aleris Hamlet Hosp, Aarhus, Denmark.
   [Bruhin, A.] Dept Trauma & Visceral Surg, Luzern, Switzerland.
   [Chariker, M.] Aesthet Plast Surg Inst, Louisville, KY USA.
   [Depoorter, M.] Acad Hosp St Jan, Dept Plast & Reconstruct Surg, Brugge, Belgium.
   [Dunn, R.] Univ Massachusetts, Sch Med, Div Plast Surg, Worcester, MA USA.
   [Dunn, R.] Mem Hlth Care, Worcester, MA USA.
   [Duteille, F.] Hop Hotel Dieu, Aesthet & Reconstruct Surg Burn Unit, Nantes, France.
   [Ferreira, F.] Hosp Pedro Hispano, Matosinhos Porto, Portugal.
   [Francos Martinez, J. M.] Hosp Univ Bellvitge, Endocrine Surg Unit, Barcelona, Spain.
   [Grudzien, G.] John Paul 2 Hosp, Dept Cardiovasc Surg & Transplantol, Krakow, Poland.
   [Hudson, D.] Groote Schuur Hosp, Dept Plast & Reconstruct Surg, ZA-7925 Cape Town, South Africa.
   [Ichioka, S.] Saitama Med Univ, Dept Plast & Reconstruct Surg, Saitama, Japan.
   [Ingemansson, R.] Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Div, Lund, Sweden.
   [Jeffery, S.] Queen Elizabeth Hosp, Royal Ctr Def Med, Birmingham B15 2TH, W Midlands, England.
   [Krug, E.] Leiden Univ, Med Ctr, NL-2300 RA Leiden, Netherlands.
   [Lee, C.] Univ Calif San Francisco, San Francisco, CA 94143 USA.
   [Lee, C.] St Marys Hosp, San Francisco, CA USA.
   [Malmsjo, M.] Skane Univ Hosp, Lund, Sweden.
   [Malmsjo, M.] Lund Univ, Dept Ophthalmol, Lund, Sweden.
   [Runkel, N.] Univ Freiburg, Freiburg, Germany.
   [Runkel, N.] Black Forest Hosp, Dept Gen Surg, Villingen, Germany.
   [Martin, R.; Smith, J.] Smith & Nephew, Kingston Upon Hull, N Humberside, England.
C3 Croydon University Hospital; University of Eastern Finland; University
   of Eastern Finland Hospital; Kuopio University Hospital; NSW Health;
   Royal Prince Alfred Hospital; University of Sydney; Concord Repatriation
   General Hospital; University of Massachusetts System; University of
   Massachusetts Worcester; Nantes Universite; CHU de Nantes; Institut
   d'Investigacio Biomedica de Bellvitge (IDIBELL); Bellvitge University
   Hospital; University of Barcelona; University of Cape Town; Saitama
   Medical University; Lund University; Skane University Hospital;
   University of Birmingham; Royal Centre for Defence Medicine; Leiden
   University - Excl LUMC; Leiden University; Leiden University Medical
   Center (LUMC); University of California System; University of California
   San Francisco; Lund University; Skane University Hospital; Lund
   University; University of Freiburg; Smith & Nephew
RP Runkel, N (通讯作者)，Postfach 2103, D-78011 Villingen Schwenningen, Germany.
EM norbert.runkel@sbk-vs.de
RI ; jeffery, steven/A-5207-2013; Birke-Sørensen, Hanne/B-6733-2015
OI Martin, Robin/0000-0002-9314-0437; Maljö, Malin/0000-0001-9849-9599;
   jeffery, steven/0000-0001-6587-5412; Ingemansson,
   Richard/0000-0001-7623-8953; 
FU SN
FX S&N provided funding for travel and accommodation for all face-to-face
   expert panel meetings, provided support regarding the published
   literature in NPWT, arranged and provided funding for the 'consultative
   phase' of the project (a symposium to 422 Healthcare professionals in
   Hamburg Feb 2010), provided support during the drafting of
   recommendations (authors Jenny Smith and Robin Martin) and provided
   medical writing services in preparation of this manuscript (author Jenny
   Smith). The recommendations reflect the independent and unbiased views
   of the panel and the consensus derived during the project and the
   content of the manuscript has not been unfairly influenced by Smith &
   Nephew.
CR [Anonymous], TASC 2 ALI DOC
   [Anonymous], TASC 2 PAD DOC
   [Anonymous], COCHRANE DATABASE SY
   [Anonymous], NPUAP REF
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NR 88
TC 83
Z9 102
U1 0
U2 47
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0965-206X
J9 J TISSUE VIABILITY
JI J. Viab.
PY 2011
VL 20
SU 1
BP S1
EP S18
DI 10.1016/j.jtv.2011.07.002
PG 18
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA 972UM
UT WOS:000306306000001
PM 22119531
DA 2026-07-24
ER

PT J
AU Hoeller, M
   Schintler, MV
   Pfurtscheller, K
   Kamolz, LP
   Tripolt, N
   Trop, M
AF Hoeller, Michael
   Schintler, Michael Valentin
   Pfurtscheller, Klaus
   Kamolz, Lars-Peter
   Tripolt, Norbert
   Trop, Marija
TI A retrospective analysis of securing autologous split-thickness skin
   grafts with negative pressure wound therapy in paediatric burn patients
SO BURNS
LA English
DT Article
DE Negative pressure wound therapy; Autologous split-thickness skin graft;
   Treatment of paediatric burns; Mobility
ID VACUUM-ASSISTED CLOSURE
AB Background and Aim: Deep dermal and full-thickness burn wounds are excised and grafted with split-thickness skin grafts. Especially in less compliant patients such as young children, conventional fixing methods can often be ineffective due to high mobility rates in this age group.
   The aim of this retrospective single-centre study was to give an overview of our experience in the fixation of autologous split-thickness skin grafts (ASTSGs) on burn wounds by negative pressure wound therapy (NPWT) in paediatric patients.
   Methods: A retrospective analysis describing 53 paediatric patients with burns or burn-related injuries who were treated as 60 individual cases were conducted. All patients received ASTSGs secured by NPWT.
   Results: Of the individual cases, 60 cases with a mean age of 8 6 years (the youngest was 3 months, the eldest was 24 years old) were treated in a single procedure with ASTSG and NPWT. Total burn surface area (TBSA) was, median (med) 4.5% (3.0-12.0%). The TBSA of deep dermal thickness to full-thickness (IIb-III degrees) burns was med 4.0% (2.0-6.0%). The TBSA treated with ASTSG and NPWT was med 3.5% (2.0-6.0%). Take rate was, med 96% (90-99%) with a total range of 70-100%. The only significant correlation that could be found was between the grafted TBSA and the take rate. The smaller the grafted TBSA the better the take rate resulted, as expected. In three cases, major complications were noted.
   Conclusion: To sum up our experience, the NPWT system has developed itself to be a constant, well-implemented and useful tool in securing ASTSGs to the wound bed. The main advantage of the technique is a much higher mobility of the patient compared to conventional fixation methods. The high compliance rate of an often challenging group of patients such as children recompenses possible higher costs compared to conventional fixation methods. (C) 2013 Elsevier Ltd and ISBI. All rights reserved.
C1 [Hoeller, Michael; Pfurtscheller, Klaus; Trop, Marija] Med Univ Graz, Dept Paediat & Adolescent Med, Childrens Burn Unit, A-8010 Graz, Austria.
   [Schintler, Michael Valentin; Kamolz, Lars-Peter] Med Univ Graz, Dept Surg, Div Plast & Reconstruct Surg, A-8010 Graz, Austria.
   [Tripolt, Norbert] Med Univ Graz, Dept Internal Med, Div Endocrinol & Metab, A-8010 Graz, Austria.
C3 Medical University of Graz; Medical University of Graz; Medical
   University of Graz
RP Hoeller, M (通讯作者)，Med Univ Graz, Dept Paediat & Adolescent Med, Childrens Burn Unit, Auenbruggerpl 34-2, A-8010 Graz, Austria.
EM michael.hoeller@klinikum-graz.at
RI Tripolt, Norbert/AFP-4429-2022
OI Kamolz, Lars-Peter/0000-0002-5975-876X
CR [Anonymous], COCHRANE DATABASE SY
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NR 21
TC 18
Z9 28
U1 0
U2 2
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0305-4179
EI 1879-1409
J9 BURNS
JI Burns
PD SEP
PY 2014
VL 40
IS 6
BP 1116
EP 1120
DI 10.1016/j.burns.2013.12.007
PG 5
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA AP2JL
UT WOS:000341898400007
PM 24438740
DA 2026-07-24
ER

PT J
AU Alipour, V
   Rezapour, A
   Ebrahimi, M
   Arabloo, J
AF Alipour, Vahid
   Rezapour, Aziz
   Ebrahimi, Mehdi
   Arabloo, Jalal
TI Cost-Utility Analysis of Negative Pressure Wound Therapy Compared With
   Traditional Wound Care in the Treatment of Diabetic Foot Ulcers in Iran
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE cost-utility analysis; negative pressure wound therapy; traditional
   wound care; diabetic foot ulcer
ID VACUUM-ASSISTED CLOSURE; DRESSINGS
AB Introduction. Negative pressure wound therapy (NPWT; also known as vacuum-assisted wound closure) has emerged as a promising option that may result in better health outcomes. Objective. This study analyzed the cost-utility of NPWT compared with traditional wound care (TWC) for the treatment of patients with diabetic foot ulcers in Iran from the perspective of health care providers. Materials and Methods. This economic evaluation study was conducted in 2016 to estimate the incremental cost effectiveness ratio of NPWT compared with TWC. The Markov model was applied, incorporating the 7 health states of uninfected, infected, infected post-amputation, healed, healed postamputation, amputation, and death for a 1-year time period and monthly cycles (12 cycles). Quality-adjusted life years (QALYs) were calculated from utility weights of each diagnosis, which were derived from the published literature. Costs for each diagnosis were estimated monthly and separately based on inpatient and outpatient care. The analysis of cost-effectiveness and sensitivity for uncertain parameters was carried out using TreeAge Pro 2011 software. Results. A total of 200 patient records (NPWT = 100; TWC = 100) were analyzed in this study. The results indicated that annual cost per patient for NPWT and TWC strategies were $5165 +/- $3258 and $9833 +/- $5861, respectively. In addition, mean effectiveness per patient per year for NPWT and TWC strategies were 8.9026 +/- 1.7622 and 8.7974 +/- 1.855 QALYs, respectively. When treatment with NPWT was compared with TWC using the incremental cost-effectiveness ratio of -$44 370 per QALY, NPWT was shown as a more cost-effective treatment strategy than TWC. Conclusions. The results of the study show that NPWT is less costly and more effective compared with TWC. In addition, NPWT reduces the number of amputations and increases the number of healed wounds, decreasing patients' and payers' costs. The sensitivity analysis of parameters proved the robustness of the Markov model.
C1 [Alipour, Vahid; Rezapour, Aziz; Arabloo, Jalal] Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran 1996713883, Tehran, Iran.
   [Ebrahimi, Mehdi] Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Endocrinol & Metab Clin Sci Inst, Tehran, Iran.
C3 Iran University of Medical Sciences; Tehran University of Medical
   Sciences
RP Arabloo, J (通讯作者)，Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran 1996713883, Tehran, Iran.
EM arabloo_j64@yahoo.com
RI Alipour, Vahid/K-5099-2019; rezapour, aziz/M-2817-2018; arabloo,
   Jalal/K-1829-2019
OI arabloo, Jalal/0000-0003-1223-4528
FU Iran National Institute of Health Research, Tehran University of Medical
   Sciences [93264]
FX This study was funded and supported by Iran National Institute of Health
   Research, Tehran University of Medical Sciences; Grant No: 93264.
CR Alipour V, 2014, IRAN J RADIOL, V11, DOI 10.5812/iranjradiol.18738
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NR 31
TC 6
Z9 8
U1 2
U2 13
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD FEB
PY 2021
VL 33
IS 2
BP 50
EP 56
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA SD0QB
UT WOS:000651066300006
PM 33591928
DA 2026-07-24
ER

PT J
AU Sharran, M
   Balaji, G
   Patel, SA
   Badhe, B
AF Sharran, M.
   Balaji, Gopisankar
   Patel, Sukruth Anand
   Badhe, Bhawana
TI Comparison of Scar Quality Between Primary Incisional Negative Pressure
   Wound Therapy and Conventional Surgical Dressing in Patients with Closed
   Forearm Fractures Treated Surgically: A Randomised Controlled Trial
SO AESTHETIC PLASTIC SURGERY
LA English
DT Article
DE Forearm; Fractures; Wound; Dressing; Negative pressure
ID VACUUM-ASSISTED CLOSURE; MANAGEMENT
AB BackgroundWound healing and the quality of the scar plays a key role in deciding which dressing technique is better.ObjectiveThe study aimed to determine if primary incisional negative pressure wound therapy provides better scar quality compared to conventional dressing following definitive fixation of closed forearm fractures.MethodsA prospective randomized control trial of patients diagnosed with acute closed forearm fractures who underwent open reduction and internal fixation from April 2022 to January 2024. Patients received either a standard sterile dressing or incisional negative pressure wound therapy (iNPWT). The primary outcome was comparing the histopathological scar quality by examining collagen composition at 12 weeks. Secondary outcomes included assessment of surgical site infection (ASEPSIS Score) and clinical scar assessment using the Patient and Observer Scar Assessment Scale. Univariate logistic regression analyses were performed.Results34 patients were included, 47% received iNPWT (n = 16), and 53% received standard dressings (n = 18). With Masson's trichrome stain,15 participants (93.7%) in the intervention group experienced a favourable outcome with an unadjusted relative risk of 1.13 (95% CI: 0.88-1.43, p = 0.341). With Reticulin stain, 12 participants (75%) in the intervention group exhibited desirable results with an unadjusted relative risk of 0.79 (95% CI: 0.58-1.07,p = 0.13). The intervention group had a mean ASEPSIS score of 1.75 with an SD of 2.11 [95% CI-0.62 to 2.87, p = 0.14]. The calculated difference in mean Patient scar scores between the two groups was 7.31 (p = 0.003), and the observer score was 4.5 (p = 0.043).ConclusionsPatients who underwent iNPWT showed cosmetic satisfaction of scar and favourable outcomes in histopathological assessment with Masson's trichrome stain.Level of Evidence IIIThis journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
C1 [Sharran, M.; Balaji, Gopisankar; Badhe, Bhawana] Jawaharlal Inst Postgrad Med Educ & Res, Dept Orthopaed, Pondicherry, India.
   [Patel, Sukruth Anand] Maax Super Special Hosp, Shivamogga, Karnataka, India.
C3 Jawaharlal Institute of Postgraduate Medical Education & Research
RP Balaji, G (通讯作者)，Jawaharlal Inst Postgrad Med Educ & Res, Dept Orthopaed, Pondicherry, India.
EM drgopi9596@gmail.com
RI /AAP-4163-2021
OI M, Sharran/0009-0000-9864-3220
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NR 18
TC 2
Z9 2
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0364-216X
EI 1432-5241
J9 AESTHET PLAST SURG
JI Aesthet. Plast. Surg.
PD FEB
PY 2026
VL 50
IS 3
BP 1411
EP 1420
DI 10.1007/s00266-025-05014-4
EA JUN 2025
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FD3KX
UT WOS:001518292800001
PM 40576813
DA 2026-07-24
ER

PT J
AU Rahmanian-Schwarz, A
   Willkomm, LM
   Ganser, P
   Hirt, B
   Schaller, HE
AF Rahmanian-Schwarz, Afshin
   Willkomm, Lina-Marie
   Ganser, Philipp
   Hirt, Bernhard
   Schaller, Hans-Eberhard
TI A novel option in negative pressure wound therapy (NPWT) for chronic and
   acute wound care
SO BURNS
LA English
DT Article
DE Negative pressure wound therapy; RENASYS GO; VAC; Foam-based NPWT
   system; Wound dressing; Acute and chronic wounds
ID VACUUM-ASSISTED CLOSURE; THICKNESS SKIN-GRAFTS; CLINICAL-EFFICACY;
   MANAGEMENT; TRIAL; STATE
AB Introduction: Negative pressure wound therapy (NPWT) has become a widely accepted technique in treatment of all kinds of wounds. After a long period of clinical application of the V.A.C.(TM) system (KCI Inc., San Antonio, Texas, USA) a number of options for delivery of NPWT are now commercially available. An urgent need exists for evidence demonstrating clinical efficacy of these new devices to support clinicians regarding their choice of NPWT.
   Methods: 42 patients with an acute or chronic wound were randomly assigned to either treatment by V.A.C.(TM) (group A) or therapy with an alternative newly available polyurethane foam-based NPWT system (RENASYS GO (TM) - F/P, Smith & Nephew GmbH) (group B). In both groups NPWT was applied after surgical debridement to prepare the wound bed for skin grafting. After skin grafting NPWT was applied additionally to secure skin grafts and improve grafts survival. Primary outcome measures were the time to complete healing (days) and duration of the NPWT application (days). Secondary outcome measures were the number of dressing changes and reported complications. In addition, we evaluated the cost-benefit in the clinical implementation.
   Results: There were no significant differences comparing the investigated parameters between both groups. Especially average time to complete healing and average time NPWT was applied did not differ (p > 0.05). No complications occurred in either group. By an almost identical supply agreement of both providers for our hospital RENASYS (TM) system appeared to be more cost-effective.
   Conclusion: After a long period of preserving a monopoly market position of the V.A.C.(TM) system, a new comparable option was successfully tested in this preliminary study. The polyurethane foam-based NPWT system (RENASYS GO (TM) - F/P, Smith & Nephew GmbH) is an efficient and cost-effective alternative NPWT system, which we effectively implemented in therapeutic management of different kinds of wounds. (C) 2011 Elsevier Ltd and ISBI. All rights reserved.
C1 [Rahmanian-Schwarz, Afshin; Willkomm, Lina-Marie; Ganser, Philipp; Schaller, Hans-Eberhard] Univ Tubingen, BG Trauma Ctr, Dept Plast Reconstruct Hand & Burn Surg, D-72074 Tubingen, Germany.
   [Hirt, Bernhard] Univ Tubingen, Dept Anat, D-72074 Tubingen, Germany.
C3 Eberhard Karls University of Tubingen; Eberhard Karls University of
   Tubingen
RP Rahmanian-Schwarz, A (通讯作者)，Univ Tubingen, BG Trauma Ctr, Dept Plast Reconstruct Hand & Burn Surg, D-72074 Tubingen, Germany.
EM arahmanian@bgu-tuebingen.de
CR [Anonymous], GER MED SCI
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   KAIRINOS N, 2009, PLAST RECONSTR SURG, V123, P99
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NR 28
TC 41
Z9 45
U1 0
U2 22
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0305-4179
EI 1879-1409
J9 BURNS
JI Burns
PD JUN
PY 2012
VL 38
IS 4
BP 573
EP 577
DI 10.1016/j.burns.2011.10.010
PG 5
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA 937VQ
UT WOS:000303691500016
PM 22100423
DA 2026-07-24
ER

PT J
AU Ward, C
   Ciraulo, D
   Coulter, M
   Desjardins, S
   Liaw, L
   Peterson, S
AF Ward, Christopher
   Ciraulo, David
   Coulter, Michael
   Desjardins, Steven
   Liaw, Lucy
   Peterson, Sarah
TI Does treatment of split-thickness skin grafts with negative-pressure
   wound therapy improve tissue markers of wound healing in a porcine
   experimental model?
SO JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
LA English
DT Article
DE Negative-pressure wound therapy; split thickness skin graft
ID VACUUM-ASSISTED CLOSURE; DEVICE; MIGRATION
AB BACKGROUND: Negative-pressure wound therapy (NPWT) has been used for to treat wounds for more than 15 years and, more recently, has been used to secure split-thickness skin grafts. There are some data to support this use of NPWT, but the actual mechanism by which NPWT speeds healing or improves skin graft take is not entirely known. The purpose of this project was to assess whether NPWT improved angiogenesis, wound healing, or graft survival when compared with traditional bolster dressings securing split-thickness skin grafts in a porcine model.
   METHODS: We performed two split-thickness skin grafts on each of eight 30 kg Yorkshire pigs. We took graft biopsies on postoperative days 2, 4, 6, 8, and 10 and submitted the samples for immunohistochemical staining, as well as standard hematoxylin and eosin staining. We measured the degree of vascular ingrowth via immunohistochemical staining for von Willenbrand's factor to better identify blood vessel epithelium. We determined the mean cross-sectional area of blood vessels present for each representative specimen, and then compared the bolster and NPWT samples. We also assessed each graft for incorporation and survival at postoperative day 10.
   RESULTS: Our analysis of the data revealed that there was no statistically significant difference in the degree of vascular ingrowth as measured by mean cross-sectional capillary area (p = 0.23). We did not note any difference in graft survival or apparent incorporation on a macroscopic level, although standard hematoxylin and eosin staining indicated that microscopically, there seemed to be better subjective graft incorporation in the NPWT samples and a nonsignificant trend toward improved graft survival in the NPWT group.
   CONCLUSION: We were unable to demonstrate a significant difference in vessel ingrowth when comparing NPWT and traditional bolster methods for split-thickness skin graft fixation. More studies are needed to elucidate the manner by which NPWT exerts its effects and the true clinical magnitude of these effects. (J Trauma Acute Care Surg. 2012;73: 447-451. Copyright (c) 2012 by Lippincott Williams & Wilkins)
C1 [Ward, Christopher; Ciraulo, David; Desjardins, Steven] Maine Med Ctr, Dept Surg, Portland, ME 04102 USA.
   [Liaw, Lucy; Peterson, Sarah] Maine Med Ctr, Res Inst, Scarborough, ME USA.
C3 Maine Medical Center; Maine Medical Center
RP Ward, C (通讯作者)，Maine Med Ctr, Dept Surg, 22 Bramhall St, Portland, ME 04102 USA.
EM wardc1@mmc.org
FU Maine Medical Center Mentored Research Committee; National Center for
   Research Resources at the National Institutes of Health [2P20RR018789,
   5P30 RR030927]
FX This study was supported with a grant from the Maine Medical Center
   Mentored Research Committee. This study also used materials provided
   free of cost by Smith and Nephew. There was no direct pharmaceutical or
   industry financial support.This study was conducted using existing
   resources funded by two grants, both from the National Center for
   Research Resources at the National Institutes of Health 2P20RR018789
   (PI: Wojchowski) and 5P30 RR030927 (PI: Friesel).
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NR 19
TC 6
Z9 6
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 2163-0755
EI 2163-0763
J9 J TRAUMA ACUTE CARE
JI J. Trauma Acute Care Surg.
PD AUG
PY 2012
VL 73
IS 2
BP 447
EP 450
DI 10.1097/TA.0b013e31825aa9ea
PG 4
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Surgery
GA 992VG
UT WOS:000307807400039
PM 22846954
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Nakamura, H
   Makiguchi, T
   Hino, A
   Shirabe, K
   Yokoo, S
AF Nakamura, Hideharu
   Makiguchi, Takaya
   Hino, Ayumu
   Shirabe, Ken
   Yokoo, Satoshi
TI Effect on bacterial load of a DACC-coated dressing as a wound contact
   layer in negative pressure wound therapy
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE bacterial load; DACC; dialkylcarbamoyl chloride-coated dressing;
   negative pressure wound therapy; skin graft; Sorbact; ulcer; wound;
   wound care; wound dressing; wound healing
ID VACUUM-ASSISTED CLOSURE; INFECTION; ULCERS
AB Objective: Dialkylcarbamoyl chloride (DACC)-coated dressing is hydrophobic material that absorbs exudate and binds the bacteria within it to the dressing. This property has led to the use of DACC-coated dressings for a wide range of wounds. However, the bacterial load binding capacity in this dressing used with negative pressure wound therapy (NPWT) has not been evaluated, to the best of the authors' knowledge. The aim of this study was to examine bacterial loads at the wound surface in the use of NPWT with a DACC-coated dressing as a wound contact layer. Method: A single-centre study was performed in patients with skin ulcers who had received a split-thickness skin graft (STSG). Each skin ulcer was divided into two comparable regions, one covered with a DACC-coated dressing (Sorbact Compress; Abigo Medical AB, Sweden) (DACC group) and the other with silicone gauze (control group). NPWT was used to fix the STSG. Swab samples were collected from the wound surface and the number of bacterial colony-forming units (CFUs) was measured to assess bacterial load on the day of surgery (day 0) and upon NPWT removal on day 7 postoperatively. Skin graft survival rates were compared between the two groups. Results: The experimental cohort comprised 15 patients, yielding 15 paired regions per group (DACC and control). On day 0, there was no difference in the number of CFUs between the control and DACC groups (p=0.136). However, on day 7, the DACC group had a lower CFU count than the control group (p=0.0175). The skin graft survival rate did not differ significantly between the two groups (p=0.938). Conclusion: In this study, use of a DACC-coated dressing reduced bacterial growth when using NPWT. This suggests that this combination treatment might contribute to the promotion of wound healing. Declaration of interest: The authors have no conflicts of interest.
C1 [Nakamura, Hideharu] Natl Hosp Org Takasaki Gen Med Ctr, Dept Plast & Reconstruct Surg, Takasaki, Japan.
   [Makiguchi, Takaya; Yokoo, Satoshi] Gunma Univ, Dept Oral & Maxillofacial Surg, Grad Sch Med, Maebashi, Japan.
   [Hino, Ayumu] Natl Hosp Org Takasaki Gen Med Ctr, Dept Clin Lab Sci, Takasaki, Japan.
   [Shirabe, Ken] Gunma Univ, Grad Sch Med, Dept Gen Surg Sci, Maebashi, Japan.
C3 Gunma University; Gunma University
RP Nakamura, H (通讯作者)，Natl Hosp Org Takasaki Gen Med Ctr, Dept Plast & Reconstruct Surg, Takasaki, Japan.
EM hidemoku0211@gmail.com
OI Nakamura, Hideharu/0000-0001-9603-2805
CR Anghel EL, 2016, PLAST RECONSTR SURG, V138, p129S, DOI 10.1097/PRS.0000000000002645
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   Bateman S, 2015, Wounds UK, V11, P82
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   Rippon MG, 2021, J WOUND CARE, V30, P284, DOI 10.12968/jowc.2021.30.4.284
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   Sen CK, 2019, ADV WOUND CARE, V8, P39, DOI 10.1089/wound.2019.0946
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NR 31
TC 1
Z9 1
U1 1
U2 1
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD NOV
PY 2025
VL 34
IS 11
BP 952
EP 956
DI 10.12968/jowc.2023.0058
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 9TM2A
UT WOS:001614638200001
PM 41201877
DA 2026-07-24
ER

PT J
AU Beele, H
   Gomes, CF
   Vieira, N
   Castro, J
   Alves, P
AF Beele, Hilde
   Gomes, Carlos Filipe
   Vieira, Nuna
   Castro, Joao
   Alves, Paulo
TI Dynamic management of pressure injuries using a portable canister-based
   single-use negative pressure wound therapy device
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE low-to-moderate exuding wounds; exudate management; pressure injuries;
   single-use negative pressure wound therapy system; wound dressing; wound
   circle; wound care; wound healing
ID VACUUM-ASSISTED CLOSURE; EVIDENCE-BASED RECOMMENDATIONS; CARE;
   MULTICENTER; STEPS; MMP-8
AB Objective: Negative pressure wound therapy (NPWT) helps to reduce tissue deficits by removing excess fluid, promoting granulation tissue formation and stabilising the wound environment. This prospective, open, non-comparative clinical study assessed these factors using a canister-based single-use NPWT (CB-suNPWT) system for the management of low-to-moderate exuding pressure injuries (PIs). Method: This 28-day multicentre investigation assessed wound progress compared with the previous visit at which the CB-suNPWT system was applied and also from baseline to study completion. Additional endpoints included: changes in wound area and volume; tissue type; exudation (amount, nature and odour); periwound skin condition; pain levels at dressing removal; tissue ingrowth into foam; system wear time; product consumption; and therapy adherence. Adverse events (AEs) were also recorded. Results: The study recruited 35 patients with PIs at four sites in Portugal. All were included in the full analysis group. Statistically significant wound progress was observed, with 80.6% of cases showing improvement compared with the previous visit (95% confidence interval: 72.7, 80.6; p<0.05). Improvements in wound tissue and exudate levels, type and odour were also observed, and a marked increase in granulation tissue reported, combined with reductions in wound size and volume. Tissue ingrowth into the foam was reported in only two (0.57%) dressing changes. The device was well received by both investigators and patients, easy to use and managed exudate levels effectively. A minimal number of AEs were reported. Conclusion: In this study, the CB-suNPWT device promoted improvements in the wound bed, resulting in progression towards healing of low-to-moderate exuding PIs. Declaration of interest: This study was sponsored by M & ouml;lnlycke Health Care, M & ouml;lndal, Sweden. The authors have no conflicts of interest to declare.
C1 [Beele, Hilde] Ghent Univ Hosp, Dept Dermatol, Ghent, Belgium.
   [Beele, Hilde] Ghent Univ Hosp, Wound Care Ctr, Ghent, Belgium.
   [Gomes, Carlos Filipe] Complexo Social Moita Rua Misericordia, Aveiro, Portugal.
   [Vieira, Nuna] Unidade Cuidados Continuados Antonio Francisco Gui, Vizela, Portugal.
   [Castro, Joao] Wecare Saude Unidade Cuidados Continuados & Paliat, Povoa De Varzim, Portugal.
   [Alves, Paulo] Catholic Univ Portugal, Ctr Interdisciplinary Res Hlth CIIS, P-3504505 Viseu, Portugal.
   [Alves, Paulo] Trofa Saude Hosp Cent Hosp Trofa, Vila Do Conde, Portugal.
C3 Ghent University; Ghent University Hospital; Ghent University; Ghent
   University Hospital; Universidade Catolica Portuguesa
RP Beele, H (通讯作者)，Ghent Univ Hosp, Dept Dermatol, Ghent, Belgium.
EM Hilde.Beele@uzgent.be
RI Alves, Paulo/AAD-1391-2019
OI Alves, Paulo/0000-0002-6348-3316
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   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
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   Ciliberti M., 2023, WOUNDS INT, V14, P46
   Dwivedi MK, 2017, J WOUND OSTOMY CONT, V44, P343, DOI 10.1097/WON.0000000000000333
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NR 34
TC 0
Z9 0
U1 1
U2 1
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD FEB
PY 2026
VL 35
IS 2
BP 125
EP 136
DI 10.12968/jowc.2025.0541
PG 12
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA DM3EM
UT WOS:001686817700001
PM 41649921
DA 2026-07-24
ER

PT J
AU Perry, KL
   Rutherford, L
   Sajik, DMR
   Bruce, M
AF Perry, Karen L.
   Rutherford, Lynda
   Sajik, David M. R.
   Bruce, Mieghan
TI A preliminary study of the effect of closed incision management with
   negative pressure wound therapy over high-risk incisions
SO BMC VETERINARY RESEARCH
LA English
DT Article
DE Negative Pressure Wound Therapy; High-Energy Fracture; Arthrodesis;
   Swelling; Wound discharge
ID VACUUM-ASSISTED CLOSURE; PERISTERNAL THORACIC WALL; BLOOD-FLOW; SURGICAL
   INCISIONS; CALCANEAL FRACTURES; ORTHOPEDIC-SURGERY; INTERNAL-FIXATION;
   SKIN; CAT; DOGS
AB Background: Certain postoperative wounds are recognised to be associated with more complications than others and may be termed high-risk. Wound healing can be particularly challenging following high-energy trauma where wound necrosis and infection rates are high. Surgical incision for joint arthrodesis can also be considered high-risk as it requires extensive and invasive surgery and postoperative distal limb swelling and wound dehiscence are common. Recent human literature has investigated the use of negative pressure wound therapy (NPWT) over high-risk closed surgical incisions and beneficial effects have been noted including decreased drainage, decreased dehiscence and decreased infection rates. In a randomised, controlled study twenty cases undergoing distal limb high-energy fracture stabilisation or arthrodesis were randomised to NPWT or control groups. All cases had a modified Robert-Jones dressing applied for 72 h postoperatively and NPWT was applied for 24 h in the NPWT group. Morphometric assessment of limb circumference was performed at six sites preoperatively, 24 and 72 h postoperatively. Wound discharge was assessed at 24 and 72 h. Postoperative analgesia protocol was standardised and a Glasgow Composite Measure Pain Score (GCPS) carried out at 24, 48 and 72 h. Complications were noted and differences between groups were assessed.
   Results: Percentage change in limb circumference between preoperative and 24 and 72 h postoperative measurements was significantly less at all sites for the NPWT group with exception of the joint proximal to the surgical site and the centre of the operated bone at 72 h. Median discharge score was lower in the NPWT group than the control group at 24 h. No significant differences in GCPS or complication rates were noted.
   Conclusions: Digital swelling and wound discharge were reduced when NPWT was employed for closed incision management. Larger studies are required to evaluate whether this will result in reduced discomfort and complication rates postoperatively.
C1 [Perry, Karen L.] Michigan State Univ, Coll Vet Med, Dept Small Anim Clin Sci, E Lansing, MI 48824 USA.
   [Rutherford, Lynda; Sajik, David M. R.] Royal Vet Coll, Dept Clin Sci & Serv, Hatfield AL9 7TA, Herts, England.
   [Bruce, Mieghan] Royal Vet Coll, Dept Prod & Populat Hlth, Hatfield AL9 7TA, Herts, England.
C3 Michigan State University; University of London; University of London
   Royal Veterinary College; University of London; University of London
   Royal Veterinary College
RP Perry, KL (通讯作者)，Michigan State Univ, Coll Vet Med, Dept Small Anim Clin Sci, 736 Wilson Rd, E Lansing, MI 48824 USA.
EM kperry@cvm.msu.edu
RI Bruce, Mieghan/K-2472-2019; Perry, Karen/AAY-7641-2020
OI Bruce, Mieghan/0000-0003-3176-2094; Perry, Karen/0000-0001-6456-1817
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NR 58
TC 12
Z9 15
U1 0
U2 10
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1746-6148
J9 BMC VET RES
JI BMC Vet. Res.
PD NOV 9
PY 2015
VL 11
AR 279
DI 10.1186/s12917-015-0593-4
PG 12
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA CV6GW
UT WOS:000364369700002
PM 26552901
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Seidel, D
   Mathes, T
   Lefering, R
   Storck, M
   Lawall, H
   Neugebauer, EAM
AF Seidel, Doerthe
   Mathes, Tim
   Lefering, Rolf
   Storck, Martin
   Lawall, Holger
   Neugebauer, Edmund A. M.
TI Negative pressure wound therapy versus standard wound care in chronic
   diabetic foot wounds: study protocol for a randomized controlled trial
SO TRIALS
LA English
DT Article
DE Diabetic foot wound; Amputation wound; Chronic wound; Foot ulcer;
   Diabetic foot; Foot diseases; Diabetes complications; Diabetes mellitus;
   Negative pressure wound therapy
ID VACUUM-ASSISTED CLOSURE
AB Background: In August 2010, the Federal Joint Committee (G-BA) decided that negative pressure wound therapy (NPWT) would not be reimbursable in German ambulatory care. This decision was based on reports from the Institute for Quality and Efficiency in Health Care (IQWiG), which concluded that there is no convincing evidence in favor of NPWT. The aim of this diabetic foot study (DiaFu study) is to evaluate whether the clinical, safety and economic results of NPWT are superior to the results of standard wound treatment.
   Methods/Design: The DiaFu study is designed as a national, multicenter, randomized controlled clinical superiority trial with a special focus on outpatient care in Germany. Competent patients in inpatient and outpatient care suffering from a chronic diabetic foot wound for a minimum of four weeks may be included in the study. The trial evaluates the treatment outcome of the application of a technical medical device which is based on the principle of NPWT (intervention group) in comparison to standard moist wound therapy (control group). All treatment systems used in the intervention group bear the symbol of free trade capacity in the European Union (CE mark) and will be operated within normal conditions of clinical routine and according to manufacturer's instructions. Primary endpoints are the time to complete wound healing and the rate of wound healing achieved in each group within the maximum study treatment time of 16 weeks. Primary endpoints will be confirmed by blinded assessment of wound photographs.
   Discussion: The DiaFu study will provide solid evidence regarding the efficacy and effectiveness of NPWT until 31 December 2014, the date when G-BA plans to decide on future reimbursement of NPWT in both ambulatory and in-hospital care. The study is designed to comply with all quality requirements of G-BA and IQWiG and will contribute to evidence-based wound care in Germany. The study has been initiated by the statutory health insurance companies in Germany and is co-funded by two manufacturers of NPWT systems.
C1 [Seidel, Doerthe; Mathes, Tim; Lefering, Rolf; Neugebauer, Edmund A. M.] Univ Witten Herdecke, Sch Med, Fac Hlth, Inst Res Operat Med IFOM, D-51109 Cologne, Germany.
   [Storck, Martin] Stadt Klinikum Karlsruhe gGmbH, D-76133 Karlsruhe, Germany.
   [Lawall, Holger] Asklepios Westklinikum Hamburg, Abt Angiol Diabetol, D-22559 Hamburg, Germany.
C3 Witten Herdecke University; Municipal Hospital Karlsruhe
RP Seidel, D (通讯作者)，Univ Witten Herdecke, Sch Med, Fac Hlth, Inst Res Operat Med IFOM, Ostmerheimer Str 200,Bldg 38, D-51109 Cologne, Germany.
EM Doerthe.Seidel@uni-wh.de
RI /L-6893-2017
FU Kinetic Concepts Incorporated (KCI); Smith Nephew (SN)
FX The authors declare that they have no personal competing interests. The
   overall study project was initiated and is funded by the involved
   statutory health insurance companies in Germany. This includes the
   provision of integrated care contracts for ambulant NPWT of study
   patients and for an additional cohort. The study is co-funded by the
   manufacturers of the evaluated medical products Kinetic Concepts
   Incorporated (KCI) and Smith & Nephew (S&N). This includes the personnel
   expenses for the study team. The Institute for Research in Operative
   Medicine is planning and conducting this clinical trial as an
   independent scientific institute.
CR [Anonymous], N0403 IQWIG
   [Anonymous], N0602 IQWIG
   [Anonymous], GUID IND CHRON CUT U
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NR 17
TC 15
Z9 16
U1 0
U2 44
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1745-6215
J9 TRIALS
JI Trials
PD AUG 27
PY 2014
VL 15
AR 334
DI 10.1186/1745-6215-15-334
PG 10
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA AO3FQ
UT WOS:000341215000001
PM 25158846
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Bobkiewicz, A
   Walczak, D
   Smolinski, S
   Kasprzyk, T
   Studniarek, A
   Borejsza-Wysocki, M
   Ratajczak, A
   Marciniak, R
   Drews, M
   Banasiewicz, T
AF Bobkiewicz, Adam
   Walczak, Dominik
   Smolinski, Szymon
   Kasprzyk, Tomasz
   Studniarek, Adam
   Borejsza-Wysocki, Maciej
   Ratajczak, Andrzej
   Marciniak, Ryszard
   Drews, Michal
   Banasiewicz, Tomasz
TI Management of enteroatmospheric fistula with negative pressure wound
   therapy in open abdomen treatment: a multicentre observational study
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Enteroatmospheric fistula; Laparostomy; Negative pressure wound therapy;
   Open abdomen
ID VACUUM-ASSISTED CLOSURE; TEMPORARY ABDOMINAL CLOSURE; SMALL-BOWEL
   FISTULAS; ENTEROCUTANEOUS FISTULAS; ANASTOMOTIC LEAKAGE; COMPLICATIONS;
   PROPOSAL; TRAUMA
AB The management of enteroatmospheric fistula (EAF) in open abdomen (OA) therapy is challenging and associated with a high mortality rate. The introduction of negative pressure wound therapy (NPWT) in open abdomen management significantly improved the healing process and increased spontaneous fistula closure. Retrospectively, we analysed 16 patients with a total of 31 enteroatmospheric fistulas in open abdomen management who were treated using NPWT in four referral centres between 2004 and 2014. EAFs were diagnosed based on clinical examination and confirmed with imaging studies and classified into low (<200 ml/day), moderate (200-500 ml/day) and high (>500 ml/day) output fistulas. The study group consisted of five women and 11 men with the mean age of 526 years [standard deviation (SD) 119]. Since open abdomen management was implemented, the mean number of re-surgeries was 37 (SD 22). There were 24 EAFs located in the small bowel, while four were located in the colon. In three patients, EAF occurred at the anastomotic site. Thirteen fistulas were classified as low output (419%), two as moderate (65%) and 16 as high output fistulas (516%). The overall closure rate was 613%, with a mean time of 467 days (SD 434). In the remaining patients in whom fistula closure was not achieved (n = 12), a protruding mucosa was present. Analysing the cycle of negative pressure therapy, we surprisingly found that the spontaneous closure rate was 70% (7 of 10 EAFs) using intermittent setting of negative pressure, whereas in the group of patients treated with continuous pressure, 57% of EAFs closed spontaneously (12 of 21 EAFs). The mean number of NPWT dressing was 9 (SD 33; range 4-16). In two patients, we observed new fistulas that appeared during NPWT. Three patients died during therapy as a result of multi-organ failure. NPWT is a safe and efficient method characterised by a high spontaneous closure rate. However, in patients with mucosal protrusion of the EAFs, spontaneous closure appears to be impossible to achieve.
C1 [Bobkiewicz, Adam; Studniarek, Adam; Borejsza-Wysocki, Maciej; Ratajczak, Andrzej; Marciniak, Ryszard; Drews, Michal; Banasiewicz, Tomasz] Poznan Univ Med Sci, Dept Gen Endocrinol Surg & Gastroenterol Oncol, Przybyszewskiego 49, PL-60355 Poznan, Poland.
   [Walczak, Dominik] John Paul II Mem Hosp, Dept Gen Surg, Belchatow, Poland.
   [Smolinski, Szymon] Poznan Univ Med Sci, Dept Thorac Surg, Poznan, Poland.
   [Kasprzyk, Tomasz] Reg Specialist Hosp, Dept Gen Vasc & Oncol Surg, Slupsk, Poland.
C3 Poznan University of Medical Sciences; Poznan University of Medical
   Sciences
RP Bobkiewicz, A (通讯作者)，Poznan Univ Med Sci, Dept Gen Endocrinol Surg & Gastroenterol Oncol, Przybyszewskiego 49, PL-60355 Poznan, Poland.
EM bobofon007@gmail.com
OI Walczak, Dominik Andrzej/0000-0001-9009-5039; Bobkiewicz,
   Adam/0000-0002-4657-5788; Marciniak, Ryszard/0000-0001-7878-7403
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NR 44
TC 41
Z9 51
U1 1
U2 10
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD FEB
PY 2017
VL 14
IS 1
BP 255
EP 264
DI 10.1111/iwj.12597
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA EJ0RX
UT WOS:000392919100036
PM 27000995
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Glass, GE
   Nanchahal, J
AF Glass, Graeme E.
   Nanchahal, Jagdeep
TI The methodology of negative pressure wound therapy: Separating fact from
   fiction
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Review
DE Negative pressure wound therapy; VAC; Wound filler; Interface material;
   Tissue perfusion
ID VACUUM-ASSISTED CLOSURE; MICROVASCULAR BLOOD-FLOW; OF-THE-LITERATURE;
   RANDOMIZED CONTROLLED-TRIAL; CLINICAL-EXPERIENCE; CELL-PROLIFERATION;
   POLYURETHANE-FOAM; SEALING TECHNIQUE; MODEL; SKIN
AB Background: Negative pressure wound therapy (NPWT) is a technique that has gained such rapid acceptance for such a diversity of wound management problems that the evidence for optimal use has struggled to keep up. While clinical studies have sought to evaluate its effectiveness for a variety of acute and chronic wounds, preclinical studies have suggested that features such as the magnitude and periodicity of negative pressure, the wound filler and interface materials and the drainage conduit might introduce key pathophysiological variations at the wound bed influencing healing. Optimising the methodological approach is the key to achieving the best outcomes with NPWT. The aim of the present study was to evaluate and summarise the clinical and experimental evidence for how these methodological variations influence wound healing when using NPWT.
   Methods: A literature review was conducted to evaluate each component of NPWT inciting methodological variation with reference to clinical and preclinical variables including wound volume reduction, blood flow, granulation and growth factor stimulation.
   Results: Fourteen commercially available NPWT systems are currently available. Both foam and gauze transmit NP efficiently. While some preclinical evidence suggests foam may preferentially promote cell proliferation, there is no clear evidence to favour one wound filler. Most wound contraction occurs within the first -50 mmHg and physiological optimisation may be achieved within -80 mmHg. Cyclical NP-mediated cell mechanotransduction may alter the healing characteristics of the wound bed but no definitive clinical protocol has been established. There is insufficient evidence to credit NPWT with reduced bacterial wound colonisation.
   Conclusion: There is an urgent need to develop evidence-based NPWT regimes, tailoring the methodological aspects of therapy to the clinical need. An individualised strategy may yield improved outcomes and realise the potential of this powerful therapeutic intervention. (C) 2011 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Glass, Graeme E.; Nanchahal, Jagdeep] Univ Oxford, Kennedy Inst Rheumatol, London W6 8LH, England.
C3 University of Oxford; Kennedy Institute for Rheumatology
RP Glass, GE (通讯作者)，Univ Oxford, Kennedy Inst Rheumatol, ARC Bldg,65 Aspenlea Rd, London W6 8LH, England.
EM graemeglass@hotmail.com
RI ; Glass, Graeme/I-7011-2019
OI Nanchahal, Jagdeep/0000-0002-9579-9411; 
FU Kennedy Institute of Rheumatology Trustees; Arthritis Research UK; NIHR
   Biomedical Research Centre
FX We are grateful for support from the Kennedy Institute of Rheumatology
   Trustees, Arthritis Research UK and the NIHR Biomedical Research Centre
   funding scheme.
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NR 81
TC 39
Z9 47
U1 0
U2 27
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD AUG
PY 2012
VL 65
IS 8
BP 989
EP 1001
DI 10.1016/j.bjps.2011.12.012
PG 13
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 975CL
UT WOS:000306484300010
PM 22236476
DA 2026-07-24
ER

PT J
AU Lee, YJ
   Park, MC
   Park, DH
   Hahn, HM
   Kim, SM
   Lee, IJ
AF Lee, Yoo Jung
   Park, Myong Chul
   Park, Dong Ha
   Hahn, Hyung Min
   Kim, Sue Min
   Lee, Il Jae
TI Effectiveness of Acellular Dermal Matrix on Autologous Split-Thickness
   Skin Graft in Treatment of Deep Tissue Defect: Esthetic Subjective and
   Objective Evaluation
SO AESTHETIC PLASTIC SURGERY
LA English
DT Article
DE Acellular dermal matrix; Skin graft; Vancouver Scar Scale; Patient and
   Observer Scar Assessment Scale; Negative-pressure wound therapy
ID FLAP DONOR-SITE; TOPICAL NEGATIVE-PRESSURE; VACUUM-ASSISTED CLOSURE;
   RECONSTRUCTIVE SURGERY; THIGH FLAP; CLINICAL-TRIAL; ACUTE BURNS;
   FOLLOW-UP; SUBSTITUTION; MANAGEMENT
AB A split-thickness skin graft (STSG) is performed to cover a large full-thickness skin defect. Esthetic and functional deficits can result, and many studies have sought to overcome them. This study compared the effectiveness of the acellular dermal matrix (ADM) graft and STSG concerning esthetic and functional effectiveness of ADM on scar quality.
   Of the patients who underwent anterolateral thigh free flap from 2011 to 2015, patients who received skin graft only (n = 10) or skin graft with ADM (n = 20) for coverage of the donor site were enrolled. In all cases, autologous STSG was performed with 1:1.5 meshed 0.008-0.010-inch-thick skin. In the skin graft with ADM group, 0.008-0.013-inch-thick meshed ADM (CGderm(A (R)); CGBio, Inc., Seungnam, Korea) was co-grafted. Negative-pressure wound therapy (CuraVAC(A (R)); CGBio, Inc., Seungnam, Korea) was applied to both groups in continuous mode at -120 mmHg. We investigate early outcomes (skin loss rate, duration of negative-pressure wound therapy, days to removal of stitches, days to achieve complete healing, and complications) and late outcomes in terms of scar quality (vascularity, pigmentation, pliability and height) and graft-related symptoms (itching sensation and pain). Assessments used the Vancouver Scar Scale and the Patient and Observer Scar Assessment Scale. Skin fold was measured to evaluate the elasticity of scar tissue.
   In the Vancouver Scar Scale, vascularity subscore (p = 0.003) and total score (p = 0.016) were significantly lower in the skin graft with ADM group. In Patient and Observer Scar Assessment Scale, the pain (p = 0.037) and stiffness subscores (p = 0.002), and total score (p = 0.017) were significantly lower in the skin graft with ADM group.
   Skin graft with ADM results in better scar quality in objective and subjective aspects.
C1 [Lee, Yoo Jung; Park, Myong Chul; Park, Dong Ha; Hahn, Hyung Min; Kim, Sue Min; Lee, Il Jae] Ajou Univ, Dept Plast & Reconstruct Surg, Sch Med, Worldcup Ro 164, Suwon 443721, Gyeonggi Do, South Korea.
C3 Ajou University
RP Lee, IJ (通讯作者)，Ajou Univ, Dept Plast & Reconstruct Surg, Sch Med, Worldcup Ro 164, Suwon 443721, Gyeonggi Do, South Korea.
EM i00325@live.co.kr
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NR 24
TC 25
Z9 27
U1 3
U2 14
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0364-216X
EI 1432-5241
J9 AESTHET PLAST SURG
JI Aesthet. Plast. Surg.
PD OCT
PY 2017
VL 41
IS 5
BP 1049
EP 1057
DI 10.1007/s00266-017-0891-2
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FH5FC
UT WOS:000411189300010
PM 28526905
DA 2026-07-24
ER

PT J
AU Malmsjö, M
   Ingemansson, R
   Lindstedt, S
   Gustafsson, L
AF Malmsjo, Malin
   Ingemansson, Richard
   Lindstedt, Sandra
   Gustafsson, Lotta
TI Comparison of bacteria and fungus-binding mesh, foam and gauze as
   fillers in negative pressure wound therapy - pressure transduction,
   wound edge contraction, microvascular blood flow and fluid retention
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Blood flow; Experimental surgery; Negative pressure wound therapy; Wound
   dressing; Wound healing
ID VACUUM-ASSISTED CLOSURE; EVIDENCE-BASED RECOMMENDATIONS; PERISTERNAL
   THORACIC WALL; MATRIX METALLOPROTEINASES; STEPS
AB Bacteria- and fungus-binding mesh binds with and inactivates bacteria and fungus, which makes it an interesting alternative, wound filler for negative pressure wound therapy (NPWT). This study was conducted to compare the performance of pathogen-binding mesh, foam and gauze as wound fillers in NPWT with regard to pressure transduction, fluid retention, wound contraction and microvascular blood flow. Wounds on the backs of 16 pigs were filled with pathogen-binding mesh, foam or gauze and treated with NPWT. The immediate effects of 0, -40, -60, -80 and -120 mmHg, on pressure transduction and blood flow were examined in eight pigs using laser Doppler velocimetry. Wound contraction and fluid retention were studied during 72 hours of NPWT at -80 and -120 mmHg in the other eight pigs. Pathogen-binding mesh, gauze and foam provide similar pressure transduction to the wound bed during NPWT. Blood flow was found to decrease 05 cm laterally from the wound edge and increase 25 cm from the wound edge, but was unaltered 50 cm from the wound edge. The increase in blood flow was similar with all wound fillers. The decrease in blood flow was more pronounced with foam than with gauze and pathogen-binding mesh. Similarly, wound contraction was more pronounced with foam, than with gauze and pathogen-binding mesh. Wound fluid retention was the same in foam and pathogen-binding mesh, while more fluid was retained in the wound when using gauze. The blood flow 05-5 cm from the wound edge and the contraction of the wound during NPWT were similar when using pathogen-binding mesh and gauze. Wound fluid was efficiently removed when using pathogen-binding mesh, which may explain previous findings that granulation tissue formation is more rapid under pathogen-binding mesh than under gauze. This, in combination with its pathogen-binding properties, makes this mesh an interesting wound filler for use in NPWT.
C1 [Malmsjo, Malin; Gustafsson, Lotta] Lund Univ, Dept Ophthalmol, Lund, Sweden.
   [Ingemansson, Richard; Lindstedt, Sandra] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
C3 Lund University; Lund University
RP Malmsjö, M (通讯作者)，Lund Univ, Dept Ophthalmol, Lund, Sweden.
EM malin.malmsjo@med.lu.se
RI Lindstedt, Sandra/AEM-2892-2022
OI Lindstedt, Sandra/0000-0003-4484-6473; Ingemansson,
   Richard/0000-0001-7623-8953; Maljö, Malin/0000-0001-9849-9599;
   Gustafsson, Lotta/0000-0002-9826-9133
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NR 37
TC 13
Z9 20
U1 0
U2 11
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2013
VL 10
IS 5
BP 597
EP 605
DI 10.1111/j.1742-481X.2012.01029.x
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 227DW
UT WOS:000325090300019
PM 22716081
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Halama, D
   Dreilich, R
   Lethaus, B
   Bartella, A
   Pausch, NC
AF Halama, Dirk
   Dreilich, Ruth
   Lethaus, Bernd
   Bartella, Alexander
   Pausch, Niels Christian
TI Donor-site morbidity after harvesting of radial forearm free
   flaps-comparison of vacuum-assisted closure with conventional wound
   care: A randomized controlled trial
SO JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
LA English
DT Article
DE Donor-site morbidity; Healing time; Radial forearm free flap;
   Negative-pressure wound therapy; Vacuum-assisted-closure wound therapy
ID SKIN-GRAFTS; THERAPY; RECONSTRUCTION
AB Introduction: Radial forearm free flaps (RFFF) are often used to replace tissue removed in head and neck surgery. In recent years, many attempts have been made to reduce donor-site morbidity and to prevent common complications such as infection, skin-graft necrosis, tendon exposure and subsequent impairment of hand function. One promising option is the use of vacuum-assisted-closure wound therapy (VAC). The objective of this study was to evaluate the effectiveness of VAC compared with a conventional bolster dressing (CBD).
   Material and methods: A randomized controlled trial was enrolled. Our study was prospective in design and included patients with a skin-grafted forearm defect after harvesting of RFFF. Patients who met the inclusion criteria were randomly assigned into two study arms. The predictor variable was the type of wound therapy (VAC therapy compared with CBD) and the outcome variables were (1) the size of the wound area, (2) wrist movement and (3) grip strength. Outcome variables were assessed 12 days, three weeks and eight weeks after surgery.
   Results: Fifty patients (33 males, mean age 61.7 years [SD 15.5]; 17 females, mean age 54.7 years [SD 10.5]) were included consecutively in the study. Patients in the VAC group experienced a faster postsurgical reduction of wound area and had better wrist movement; nonetheless, the differences between the VAC group and CBD group did not reach statistical significance. In contrast, the recovery of post-surgical grip strength was significantly faster in the VAC group.
   Conclusions: Our study failed to prove that VAC therapy is significantly superior to CBD for all the variable studied. Because VAC therapy has some positive effects, however, we recommend further development of this negative-pressure wound treatment, rather than the termination of its use. (C) 2019 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
C1 [Halama, Dirk; Dreilich, Ruth; Lethaus, Bernd; Bartella, Alexander; Pausch, Niels Christian] Univ Hosp Leipzig, Fac Med, Dept Oral Craniomaxillofacial & Facial Plast Surg, Liebigstr 12, D-04103 Leipzig, Germany.
C3 Leipzig University
RP Pausch, NC (通讯作者)，Univ Hosp Leipzig, Fac Med, Dept Oral Craniomaxillofacial & Facial Plast Surg, Liebigstr 12, D-04103 Leipzig, Germany.
EM niels.pausch@medizin.uni-leipzig.de
RI Lethaus, Bernd/AAC-3091-2021
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NR 38
TC 15
Z9 16
U1 0
U2 7
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE,
   LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 1010-5182
EI 1878-4119
J9 J CRANIO MAXILL SURG
JI J. Cranio-MaxilloFac. Surg.
PD DEC
PY 2019
VL 47
IS 12
BP 1980
EP 1985
DI 10.1016/j.jcms.2019.11.004
PG 6
WC Dentistry, Oral Surgery & Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dentistry, Oral Surgery & Medicine; Surgery
GA JV8KY
UT WOS:000502610100022
PM 31810850
DA 2026-07-24
ER

PT J
AU Yu, L
   Wang, Y
   Ma, D
AF Yu, L.
   Wang, Y.
   Ma, D.
TI In-Hospital Nursing Care Intervention Increasing the Effect of Vacuum
   Sealing Drainage on Wound Healing: A Meta-Analysis( vol 20 , pg 3371 ,
   2023)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Correction
CR Yu L, 2023, INT WOUND J, V20, P3371, DOI 10.1111/iwj.14169
NR 1
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JAN 25
PY 2026
VL 23
IS 2
AR e70834
DI 10.1111/iwj.70834
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA DF5LF
UT WOS:001682217300001
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Argenta, PA
   Rahaman, J
   Gretz, HF
   Nezhat, F
   Cohen, CJ
AF Argenta, PA
   Rahaman, J
   Gretz, HF
   Nezhat, F
   Cohen, CJ
TI Vacuum-assisted closure in the treatment of complex gynecologic wound
   failures
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Article
AB BACKGROUND: Complex wound failures are a source of significant morbidity and mortality. They are costly and time consuming to treat, and may evolve into chronic, debilitating conditions. Vacuum-assisted closure is a novel wound healing technique applying subatmospheric pressure to wounds to expedite healing.
   CASES: We report the successful use of vacuum-assisted closure therapy on three patients on a gynecologic oncology service with complex wound failures of various chronicity. In all cases, vacuum-assisted closure therapy was well tolerated and demonstrated efficacy within 48 hours of initiation.
   CONCLUSION: We conclude that vacuum-assisted closure therapy should be included in the armamentarium of the gynecologist addressing complex wound failures. (C) 2002 by the American College of Obstetricians and Gynecologists.
C1 CUNY, Mt Sinai Med Ctr, Div Gynecol Oncol, Dept Obstet & Gynecol, New York, NY 10029 USA.
C3 Icahn School of Medicine at Mount Sinai; City University of New York
   (CUNY) System
RP Argenta, PA (通讯作者)，CUNY, Mt Sinai Med Ctr, Div Gynecol Oncol, Dept Obstet & Gynecol, 1 Gustave L Levy Pl,Box 1170, New York, NY 10029 USA.
CR Alvarez AA, 2001, GYNECOL ONCOL, V80, P413, DOI 10.1006/gyno.2000.6092
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NR 10
TC 38
Z9 47
U1 0
U2 4
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0029-7844
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD MAR
PY 2002
VL 99
IS 3
BP 497
EP 501
AR PII S0029-7844(01)01752-5
DI 10.1016/S0029-7844(01)01752-5
PG 5
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 524JU
UT WOS:000174010300021
PM 11864680
DA 2026-07-24
ER

PT J
AU Gao, JR
   Wang, YY
   Song, JY
   Li, Z
   Ren, JN
   Wang, PG
AF Gao, Junru
   Wang, Yunyun
   Song, Jingyu
   Li, Ze
   Ren, Jianan
   Wang, Peige
TI Negative pressure wound therapy for surgical site infections: A
   systematic review and meta-analysis
SO JOURNAL OF ADVANCED NURSING
LA English
DT Review
DE advanced antimicrobial dressings; adverse event; closed suction
   irrigation system; continues irrigation suction systems; negative
   pressure wound therapy; nursing; surgical site infection; treatment;
   vacuum&#8208; assisted closure; wound healing
ID MANAGEMENT; CLOSURE; SURGERY; INTERVENTIONS; IRRIGATION; GUIDELINES;
   CONSENSUS; ALCOHOL; QUALITY; GROIN
AB Objective Negative pressure wound therapy is one of the most common treatments for infected wounds. The aim of this meta-analysis was to compare the efficacy of negative pressure wound therapy with conventional treatment methods in the treatment of surgical site infection.
   Design This study is registered with International Prospective Register of Systematic Reviews.
   Data Sources The Pubmed, Embase and the Cochrane Central Register of Controlled Trials databases were searched.
   Methods The systematic review was searched by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method. All trials reporting the use of negative pressure wound therapy for surgical site infection treatment were included regardless of surgery type. The primary outcome measure was wound healing. Secondary outcomes were length of hospital stay, medical costs, adverse events, and reoperation rates. Results are presented with 95% confidence intervals and report estimates as odds ratios. Heterogeneity was determined through the I-2 test, with I-2 > 50% indicating substantial heterogeneity and p We identified 13 eligible trial comparisons, of which 2 were randomized controlled trials and 11 cohort study. Negative pressure wound therapy in surgical site infection (SSI) patients significantly increased wound healing rate, accelerated wound healing time, increased daily wound healing area, reduced hospital stay, and reduced adverse events. However, negative pressure wound therapy was associated with increased medical costs.
   Conclusion Negative pressure wound therapy may be more effective for the treatment of surgical site infection relative to conventional debridement, dressings and other treatments. However, further high-quality randomized controlled trials are needed to determine the most optimal application of negative pressure wound therapy.
   Impact.
   Negative pressure wound therapy is the best treatment strategy for surgical site infection. This study can improve medical practitioners' awareness of negative pressure wound therapy for surgical site infection, promoting the development of relevant randomized controlled trials.
C1 [Gao, Junru; Wang, Yunyun; Song, Jingyu; Li, Ze; Ren, Jianan; Wang, Peige] Qingdao Univ, Affiliated Hosp, Dept Emergency Surg, 16 Jiangsu Rd, Qingdao 266000, Peoples R China.
   [Ren, Jianan] Southeast Univ, Jinling Hosp, Dept Surg, Lab Trauma & Surg Infect, Nanjing, Peoples R China.
C3 Qingdao University; Southeast University - China
RP Li, Z; Wang, PG (通讯作者)，Qingdao Univ, Affiliated Hosp, Dept Emergency Surg, 16 Jiangsu Rd, Qingdao 266000, Peoples R China.
EM 2018025944@qdu.edu.cn; wpgzyz@163.com
RI ze, li/AAJ-4308-2020; Wang, Yunyun/HJG-6977-2022
OI ze, li/0000-0002-2818-4396; 
FU Taishan Scholar Foundation of Shandong Province [2018092901]
FX This study is funded by Taishan Scholar Foundation of Shandong Province
   (Grant 2018092901).
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   Zeng JK, 2019, WORLD NEUROSURG, V127, pE389, DOI 10.1016/j.wneu.2019.03.130
NR 41
TC 50
Z9 59
U1 2
U2 24
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0309-2402
EI 1365-2648
J9 J ADV NURS
JI J. Adv. Nurs.
PD OCT
PY 2021
VL 77
IS 10
BP 3980
EP 3990
DI 10.1111/jan.14876
EA APR 2021
PG 11
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA UR5YO
UT WOS:000644551500001
PM 33905552
DA 2026-07-24
ER

PT J
AU Patel, A
   Delhougne, G
   Nherera, L
AF Patel, Ankur
   Delhougne, Gary
   Nherera, Leo
TI COMPARISON OF WOUND CLOSURE IN CHRONIC LOWER EXTREMITY ULCERS BETWEEN
   SINGLE-USE NEGATIVE PRESSURE WOUND THERAPY AND TRADITIONAL NEGATIVE
   PRESSURE WOUND THERAPY: A REAL-WORLD ANALYSIS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
EM ankur.patel@smith-nephew.com; gary.delhougne@smith-nephew.com;
   Leo.Nherera@smith-nephew.com
RI PATEL, ANKUR/JFS-7636-2023
CR Kirsner R, 2019, WOUND REPAIR REGEN, V27, P519, DOI 10.1111/wrr.12727
NR 1
TC 0
Z9 0
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2020
VL 47
SU 3
MA R02
BP S53
EP S53
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA MR0UY
UT WOS:000553309900126
DA 2026-07-24
ER

PT J
AU Patel, A
   Delhougne, G
   Nherera, L
AF Patel, A.
   Delhougne, G.
   Nherera, L.
TI COMPARISON OF WOUND CLOSURE IN CHRONIC LOWER EXTREMITY ULCERS BETWEEN
   SINGLE-USE NEGATIVE PRESSURE WOUND THERAPY AND TRADITIONAL NEGATIVE
   PRESSURE WOUND THERAPY: A REAL WORLD ANALYSIS
SO VALUE IN HEALTH
LA English
DT Meeting Abstract
C1 [Patel, A.] Smith & Nephew Inc, Ft Worth, TX USA.
   [Delhougne, G.; Nherera, L.] Smith & Nephew, Ft Worth, TX USA.
C3 Smith & Nephew; Smith & Nephew
NR 0
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1098-3015
EI 1524-4733
J9 VALUE HEALTH
JI Value Health
PD MAY
PY 2020
VL 23
SU 1
MA PMD45
BP S197
EP S197
PG 1
WC Economics; Health Care Sciences & Services; Health Policy & Services
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Business & Economics; Health Care Sciences & Services
GA LR6OT
UT WOS:000535812701081
DA 2026-07-24
ER

PT J
AU Myllykangas, HM
   Halonen, J
   Husso, A
   Berg, LT
AF Myllykangas, Heidi-Mari
   Halonen, Jari
   Husso, Annastiina
   Berg, Leena T.
TI Decreasing complications of pectoralis major muscle flap reconstruction
   with two modalities of negative pressure wound therapy
SO SCANDINAVIAN JOURNAL OF SURGERY
LA English
DT Article
DE Mediastinitis; sternotomy; muscle flap; negative pressure wound therapy;
   surgical wound infection
ID OPEN-HEART-SURGERY; STERNAL WOUNDS; INFECTIONS; ADVANCEMENT; MANAGEMENT
AB Background and objective: Deep sternal wound infection is a feared complication of open-heart surgery. Negative pressure wound therapy has gained an important role in the treatment of deep sternal wound infection. Incisional negative pressure wound therapy has been introduced as a method to prevent wound complications after sternotomy, and lately, after flap reconstructions in the treatment of deep sternal wound infection. We aimed to study if incisional negative pressure wound therapy with PICO (TM) had similar beneficial effect described earlier with competing commercial devices.
   Methods: This study included 82 patients treated with pectoralis major muscle flap for deep sternal wound infection during the years 2006-2020. PICO group consisted of 24 patients treated with preoperative negative pressure wound therapy and postoperative incisional negative pressure wound therapy (PICO (TM)). Two control groups included 48 patients with conventional treatment and 10 patients with preoperative negative pressure wound therapy only.
   Results: In the PICO group, the complication rate declined from 50.0% to 33.30%, major complication rate from 29.2% to 12.5%, and need for an additional flap from 14.6.% to 4.2% when compared to conventional treatment. The length of hospital stay decreased as well. Preoperative negative pressure wound therapy alone was associated with moderate decline in the complication rates. In addition, we described the use of split pectoralis major muscle flap reconstruction in 57 patients. To our knowledge, this is the largest published patient series describing this method in the treatment of deep sternal wound infection.
   Conclusions: Incisional negative pressure wound therapy with PICO (TM) seems beneficial after flap reconstruction. Split pectoralis major muscle flap is a versatile reconstruction option suitable to be used as a workhorse in the treatment of deep sternal wound infection.
C1 [Myllykangas, Heidi-Mari] Kuopio Univ Hosp, Dept Plast Surg, PL 100, Kuopio 70029, Finland.
   [Halonen, Jari] Univ Eastern Finland, Kuopio, Finland.
   [Halonen, Jari; Husso, Annastiina] Kuopio Univ Hosp, Dept Cardiothorac Surg, Kuopio, Finland.
   [Berg, Leena T.] Kainuu Cent Hosp, Dept Plast Surg, Kajaani, Finland.
C3 Kuopio University Hospital; University of Eastern Finland; University of
   Eastern Finland Hospital; University of Eastern Finland; Kuopio
   University Hospital; University of Eastern Finland; University of
   Eastern Finland Hospital
RP Myllykangas, HM (通讯作者)，Kuopio Univ Hosp, Dept Plast Surg, PL 100, Kuopio 70029, Finland.
EM Heidi.myllykangas@kuh.fi
RI Halonen, Jari/K-9329-2018
OI Husso, Annastiina/0000-0001-7109-1876; Myllykangas,
   Heidi-Mari/0000-0003-0542-987X
CR Ascherman JA, 2004, PLAST RECONSTR SURG, V114, P676, DOI 10.1097/01.PRS.0000130939.32238.3B
   Brown RH, 2017, PLAST RECONSTR SURG, V139, P1474, DOI 10.1097/PRS.0000000000003328
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   Tabley A, 2020, ANN THORAC SURG, V110, P2034, DOI 10.1016/j.athoracsur.2020.03.087
NR 25
TC 4
Z9 6
U1 1
U2 5
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1457-4969
EI 1799-7267
J9 SCAND J SURG
JI Scand. J. Surg.
PD MAR
PY 2022
VL 111
IS 1
DI 10.1177/14574969211043330
EA SEP 2021
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 3Y1NB
UT WOS:000692860300001
PM 34486448
OA hybrid
DA 2026-07-24
ER

PT J
AU Grimstad, O
AF Grimstad, Oystein
TI Single use negative-pressure wound therapy compared to standard care in
   patients after carbon dioxide laser surgery for hidradenitis suppurativa
SO DERMATOLOGIC THERAPY
LA English
DT Article
DE carbon dioxide laser; negative-pressure wound therapy; patient-reported
   outcomes
AB Negative pressure wound therapy is a commonly used treatment modality for surgical wounds healing by secondary intention. In an open, split side study with 12 patients, we compared low negative pressure wound therapy to conventional foam dressing the first postoperative week after carbon dioxide laser vaporization of hidradenitis suppurativa lesions. The primary outcome was time to complete wound healing, comparing the two intervention sites. Secondary endpoints included perception of pain during intervention period and patient registered impact of the regimes on daily life activities. Low negative pressure wound therapy the first postoperative week tended to reduce the time to complete wound healing. Patients reported significant lower pain levels from wounds treated with a negative pressure wound device the first postoperative week. Eleven out of 12 study participants had a preference to the negative pressure wound therapy regime to a conventional regime with foam dressings.
C1 [Grimstad, Oystein] Univ Hosp North Norway, Dept Dermatol, Tromso, Norway.
   [Grimstad, Oystein] UiT Arctic Univ Norway, Dept Clin Med, Tromso, Norway.
C3 UiT The Arctic University of Tromso; University Hospital of North
   Norway; UiT The Arctic University of Tromso
RP Grimstad, O (通讯作者)，Univ Hosp North Norway, Dept Dermatol, Tromso, Norway.
EM oystein.grimstad@unn.no
RI Gritad, Øystein/AAE-7596-2021
OI Gritad, Øystein/0000-0001-6783-4534
FU University Hospital of North Norway
FX The study was fully funded by the University Hospital of North Norway.
CR Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   Coll AM, 2004, J ADV NURS, V46, P124, DOI 10.1111/j.1365-2648.2003.02972.x
   Dini V, 2015, INT J LOW EXTR WOUND, V14, P236, DOI 10.1177/1534734615598890
   Dumville JC, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011278.pub2
   Grimstad O, 2019, J EUR ACAD DERMATOL, V33, P1164, DOI 10.1111/jdv.15353
   Hudson DA, 2015, INT WOUND J, V12, P195, DOI 10.1111/iwj.12080
   Hurd, 2013, EVALUATING COSTS BEN
   Hurd T, 2014, OSTOMY WOUND MANAG, V60, P30
   Institute for Quality and Efficiency in Health Care (IQWiG), 2019, IQWiG Reports-Commission No. N17-01B: Negative pressure wound therapy for wounds healing by primary intention
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   Lapins J, 2002, J AM ACAD DERMATOL, V47, P280, DOI 10.1067/mjd.2002.124601
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   Vermeulen H, 2005, BJS-BRIT J SURG, V92, P665, DOI 10.1002/bjs.5055
   Zens Y, 2020, SYST REV-LONDON, V9, DOI 10.1186/s13643-020-01476-6
   Zouboulis CC, 2015, J EUR ACAD DERMATOL, V29, P619, DOI 10.1111/jdv.12966
NR 15
TC 4
Z9 6
U1 0
U2 5
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1396-0296
EI 1529-8019
J9 DERMATOL THER
JI Dermatol. Ther.
PD JUN
PY 2022
VL 35
IS 6
AR e15483
DI 10.1111/dth.15483
EA APR 2022
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 1W8LN
UT WOS:000778503300001
PM 35373495
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Kumbasar, U
   Bonde, P
AF Kumbasar, Ulas
   Bonde, Pramod
TI Shoelace technique for the management of deep sternal wound infection
SO TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND
   CARDIOVASCULAR SURGERY
LA English
DT Article
DE Infection; sternal wound; vacuum-assisted closure system
ID VACUUM-ASSISTED CLOSURE; FASCIOTOMY WOUNDS; THERAPY
AB In this article, we describe a practical technique of managing deep sternal wound infection by combining two dynamic wound closure methods, namely gradual approximation of the wound edges using vessel loops: the shoelace technique and the vacuum -assisted closure system.
C1 [Kumbasar, Ulas; Bonde, Pramod] Yale Univ, Dept Cardiothorac Surg, Sch Med, New Haven, CT 06525 USA.
C3 Yale University
RP Kumbasar, U (通讯作者)，Yale Univ, Dept Cardiothorac Surg, Sch Med, New Haven, CT 06525 USA.
EM ulaskumbasar@gmail.com
RI kumbasar, ulas/IVV-5351-2023
CR Baum TP, 1999, ANN PLAS SURG, V42, P337, DOI 10.1097/00000637-199903000-00019
   Fowler JR, 2012, BONE JOINT RES, V1, P31, DOI 10.1302/2046-3758.13.2000022
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NR 8
TC 0
Z9 0
U1 0
U2 5
PU BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK
PI ATASEHIR
PA ORNEK MH DR SUPHI EZGI SK SARAY APT NO 11 D 6, ATASEHIR, ISTANBUL 34704,
   TURKEY
SN 1301-5680
J9 TURK GOGUS KALP DAMA
JI Turk Gogus Kalp Damar Cerrahisi Derg.
PD JUL
PY 2022
VL 30
IS 3
BP 469
EP 471
DI 10.5606/tgkdc.dergisi.2022.22025
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 3M0XF
UT WOS:000835181100021
PM 36303688
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Timmer, AS
   Zwanenburg, PR
   Eskes, AM
   Hompes, R
   Boermeester, MA
AF Timmer, Allard S.
   Zwanenburg, Pieter R.
   Eskes, Anne M.
   Hompes, Roel
   Boermeester, Marja A.
TI The Effect of Negative-Pressure Wound Therapy with Instillation Compared
   to Current Standard Care on Wound Closure Time of Infected Wounds: A
   Systematic Review and Meta-Analysis
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Review
ID ANTISEPTIC SOLUTION; NORMAL SALINE; IRRIGATION; OUTCOMES; QUALITY
AB Background: Infected wounds extend healing time and are associated with higher treatment costs than noninfected wounds. Several observational studies indicate that negative-pressure wound therapy with instillation can effectively reduce bacterial bioburden and improve wound healing. Only a few randomized trials with small sample sizes have been published, and a meta-analysis directly comparing negative-pressure wound therapy with instillation to current standard care is lacking. It is therefore uncertain whether negative-pressure wound therapy with instillation actually improves wound healing. The authors performed a systematic review and hypothesized that negative-pressure wound therapy with instillation reduces wound closure time.
   Methods: The PubMed, Embase, and CENTRAL databases were searched up to December of 2020 for English studies that compare negative-pressure wound therapy with instillation-to either negative-pressure wound therapy without instillation or to other types of wound care-for the treatment of acute or chronically infected wounds. Time to wound closure was analyzed using a random effects meta-analysis in predefined subgroups according to study design and comparative wound care.
   Results: The authors identified 14 studies describing 1053 patients. Meta-analysis of three randomized trials shows no significant difference in time to wound closure between negative-pressure wound therapy with instillation and that without (mean difference, 0.48 day; 95 percent CI, -0.70 to 1.65; I-2 = 0 percent). Data from eleven observational studies indicate that negative-pressure wound therapy with instillation reduces wound closure time (from 1.6 to 16.8 days; no pooled data). Because of imprecision and risk of bias, the available evidence provides only low-level certainty.
   Conclusions: There is currently insufficient evidence to support or discard the use of negative-pressure wound therapy with instillation for infected wounds. More randomized trials are needed to determine whether a beneficial effect can be substantiated.
C1 [Timmer, Allard S.; Zwanenburg, Pieter R.; Eskes, Anne M.; Hompes, Roel; Boermeester, Marja A.] Univ Amsterdam, Amsterdam UMC locat AMC, Dept Surg, Amsterdam Gastroenterol & Metab, Amsterdam, Netherlands.
   [Timmer, Allard S.; Zwanenburg, Pieter R.; Eskes, Anne M.; Hompes, Roel; Boermeester, Marja A.] Griffith Univ, Menzies Hlth Inst Queensland, Griffith, NSW, Australia.
   [Timmer, Allard S.; Zwanenburg, Pieter R.; Eskes, Anne M.; Hompes, Roel; Boermeester, Marja A.] Griffith Univ, Sch Nursing & Midwifery, Griffith, NSW, Australia.
C3 University of Amsterdam; Griffith University; Griffith University
RP Boermeester, MA (通讯作者)，Amsterdam UMC, Locat AMC, Amsterdam Gastroenterol & Metab Amsterdam Infect, Dept Surg, Meibergdreef 9 Suite J1A 228, NL-1100 DD Amsterdam, Netherlands.
EM m.a.boermeester@amsterdamumc.nl
RI Eskes, Anne/HKV-3276-2023; Hompes, Roel/AAN-6249-2020
OI Eskes, Anne Maria/0000-0003-1605-0195
CR Chowdhry SA, 2019, PRS-GLOB OPEN, V7, DOI 10.1097/GOX.0000000000002087
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   Gabriel Allen, 2014, Eplasty, V14, pe41
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   Garcia-Ruano A, 2016, J SURG RES, V206, P292, DOI 10.1016/j.jss.2016.08.030
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   Olsson M, 2019, WOUND REPAIR REGEN, V27, P114, DOI 10.1111/wrr.12683
   Omar M, 2016, J WOUND CARE, V25, P475, DOI 10.12968/jowc.2016.25.8.475
   Qiu Y, 2019, J CRANIO MAXILL SURG, V47, P837, DOI 10.1016/j.jcms.2019.01.031
   Schreiner W, 2020, ANN THORAC SURG, V110, P1722, DOI 10.1016/j.athoracsur.2020.04.037
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   Sterne JAC, 2019, BMJ-BRIT MED J, V366, DOI 10.1136/bmj.l4898
   Sterne JAC, 2016, BMJ-BRIT MED J, V355, DOI 10.1136/bmj.i4919
   Timmers MS, 2009, WOUND REPAIR REGEN, V17, P278, DOI 10.1111/j.1524-475X.2009.00458.x
   Upton D, 2013, J WOUND CARE, V22, P34, DOI 10.12968/jowc.2013.22.1.34
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   Yao Z, 2021, J INVEST SURG, V34, P791, DOI 10.1080/08941939.2019.1693667
NR 36
TC 3
Z9 3
U1 0
U2 9
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JUL
PY 2022
VL 150
IS 1
BP 176E
EP 188E
DI 10.1097/PRS.0000000000009232
PG 13
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 2N2DN
UT WOS:000818196600038
PM 35583955
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Janssen, N
   Laven, IEWG
   Daemen, JHT
   Hulsewé, KWE
   Vissers, YLJ
   de Loos, ER
AF Janssen, Nicky
   Laven, Iris E. W. G.
   Daemen, Jean H. T.
   Hulsewe, Karel W. E.
   Vissers, Yvonne L. J.
   de Loos, Erik R.
TI Negative pressure wound therapy for massive subcutaneous emphysema: a
   systematic review and case series
SO JOURNAL OF THORACIC DISEASE
LA English
DT Review
DE Negative pressure wound therapy; subcutaneous emphysema; systematic
   review; case series
ID MANAGEMENT; SUCTION; DRAIN
AB Background: Massive subcutaneous emphysema can cause considerable morbidity with respiratory distress. To resolve this emphysema in short-term, negative pressure wound therapy could be applied as added treatment modality. However, its use is sparsely reported, and a variety of techniques are being described. This study provides a systematic review of the available literature on the effectiveness of negative pressure wound therapy as treatment for massive subcutaneous emphysema. In addition, our institutional experience is reported through a case-series.
   Methods: The PubMed, Embase and Cochrane Library were systematically searched for publications on the use of negative pressure wound therapy for subcutaneous emphysema following thoracic surgery, trauma or spontaneous pneumothorax. Moreover, patients treated at our institution between 2019 and 2021 were retrospectively identified and analyzed.
   Results: The systematic review provided 10 articles presenting 23 cases. Studies demonstrated considerable heterogeneity regarding the location of incision, creation of prepectoral pocket, and surgical safety margin. Also closed incision negative pressure wound therapy and PICO(C) device were discussed. Despite the apparent heterogeneity, all techniques provided favorable outcomes. No complications, reinterventions or recurrences were documented. Furthermore, retrospective data of 11 patients treated at our clinic demonstrated an immediate response to negative pressure wound therapy and a full remission of the subcutaneous emphysema at the end of negative pressure wound therapy. No recurrence requiring intervention or complications were observed.
   Conclusions: The findings of this study suggest that negative pressure wound therapy, despite the varying techniques employed, is associated with an immediate regression of subcutaneous emphysema and full remission at the end of therapy. Given the relatively low sample size, no technique of choice could be identified. However, in general, negative pressure wound therapy appears to provide fast regression of subcutaneous emphysema and release of symptoms in all cases.
C1 [Janssen, Nicky; Laven, Iris E. W. G.; Daemen, Jean H. T.; Hulsewe, Karel W. E.; Vissers, Yvonne L. J.; de Loos, Erik R.] Zuyderland Med Ctr, Dept Surg, Div Gen Thorac Surg, Henri Dunantstr 5, NL-6419 PC Heerlen, Netherlands.
C3 Zuyderland Medical Center
RP de Loos, ER (通讯作者)，Zuyderland Med Ctr, Dept Surg, Div Gen Thorac Surg, Henri Dunantstr 5, NL-6419 PC Heerlen, Netherlands.
EM e.deloos@zuyderland.nl
OI Laven, Iris/0000-0001-8976-5293
CR Agha RA, 2020, INT J SURG, V84, P231, DOI 10.1016/j.ijsu.2020.11.005
   Ahmed Z, 2016, INT J SURG CASE REP, V26, P138, DOI 10.1016/j.ijscr.2016.07.031
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   Clavien PA, 2009, ANN SURG, V250, P187, DOI 10.1097/SLA.0b013e3181b13ca2
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   Wezel A, 2020, Ned Tijdschr Geneeskd, V164
NR 18
TC 7
Z9 9
U1 0
U2 1
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2072-1439
EI 2077-6624
J9 J THORAC DIS
JI J. Thorac. Dis.
PD JAN
PY 2022
VL 14
IS 1
BP 43
EP +
DI 10.21037/jtd-21-1483
EA DEC 2021
PG 14
WC Respiratory System
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System
GA YX7SS
UT WOS:000742877100001
PM 35242367
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Frear, CC
   Zang, T
   Griffin, BR
   McPhail, SM
   Parker, TJ
   Kimble, RM
   Cuttle, L
AF Frear, Cody C.
   Zang, Tuo
   Griffin, Bronwyn R.
   McPhail, Steven M.
   Parker, Tony J.
   Kimble, Roy M.
   Cuttle, Leila
TI The modulation of the burn wound environment by negative pressure wound
   therapy: Insights from the proteome
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID ASSISTED CLOSURE THERAPY; BLISTER FLUID PROTEOME; NORMALIZATION METHODS;
   EXPRESSION; CYTOSCAPE; FILAMIN; SWINE
AB Negative pressure wound therapy has been used to promote wound healing in a variety of settings, including as an adjunct to silver-impregnated dressings in the acute management of paediatric burns. Fluid aspirated by the negative pressure wound therapy system represents a potentially insightful research matrix for understanding the burn wound microenvironment and the intervention's biochemical mechanisms of action. The aim of this study was to characterize the proteome of wound fluid collected using negative pressure wound therapy from children with small-area thermal burns. Samples were obtained as part of a randomized controlled trial investigating the clinical efficacy of adjunctive negative pressure wound therapy. They were compared with blister fluid specimens from paediatric burn patients matched according to demographic and injury characteristics. Protein identification and quantification were performed via liquid chromatography tandem mass spectrometry and sequential window acquisition of all theoretical mass spectra data-independent acquisition. Proteins and biological pathways that were unique to or enriched in negative pressure wound therapy fluid samples were evaluated using principal components, partial least squares-discriminant, and gene ontology enrichment analyses. Eight viable samples of negative pressure wound therapy fluid were collected and analyzed with eight matched blister fluid samples. A total of 502 proteins were quantitatively profiled in the negative pressure wound therapy fluid, of which 444 (88.4%) were shared with blister fluid. Several proteins exhibited significant abundance differences between fluid types, with negative pressure wound therapy fluid showing a higher abundance of matrix metalloproteinase-9, arginase-1, low affinity immunoglobulin gamma Fc region receptor III-A, filamin-A, alpha-2-macroglobulin, and hemoglobin subunit alpha. The results lend support to the hypothesis that negative pressure wound therapy augments wound healing through the modulation of factors involved in the inflammatory response, granulation tissue synthesis, and extracellular matrix maintenance. Data are available via ProteomeXchange with identifier PXD023168.
C1 [Frear, Cody C.; Zang, Tuo; Griffin, Bronwyn R.; Kimble, Roy M.; Cuttle, Leila] Ctr Childrens Burns & Trauma Res, South Brisbane, Qld, Australia.
   [Frear, Cody C.; Kimble, Roy M.] Univ Queensland, Fac Med, Herston, Qld, Australia.
   [Zang, Tuo; Griffin, Bronwyn R.; McPhail, Steven M.; Parker, Tony J.; Cuttle, Leila] Queensland Univ Technol, Fac Hlth, Kelvin Grove, Qld, Australia.
   [McPhail, Steven M.] Metro South Hlth, Clin Informat Directorate, Brisbane, Qld, Australia.
   [Kimble, Roy M.] Queensland Childrens Hosp, South Brisbane, Qld, Australia.
C3 University of Queensland; Queensland University of Technology (QUT);
   Childrens Health Queensland Hospital & Health Service; Queensland
   Childrens Hospital
RP Frear, CC (通讯作者)，Childrens Hlth Res Ctr, Ctr Childrens Burns & Trauma Res, 62 Graham St, South Brisbane, Qld 4101, Australia.
EM cody.frear@uqconnect.edu.au
RI ; Kimble, Roy/B-4160-2011; Cuttle, Leila/U-9376-2017; Griffin,
   Bronwyn/AEB-6299-2022; McPhail, Steven/JMR-2141-2023
OI Frear, Cody/0000-0002-6011-2472; Zang, Tuo/0000-0002-1280-9638; Parker,
   Tony/0000-0002-5118-524X; Cuttle, Leila/0000-0002-2282-4815; Griffin,
   Bronwyn/0000-0002-6182-9125; McPhail, Steven/0000-0002-1463-662X
FU Smith Nephew [150510-0335/53]
FX Smith & Nephew, Grant/Award Number: #150510-0335/53
CR [Anonymous], 2006, INT WOUND J
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   Zang T, 2016, EXPERT REV PROTEOMIC, V13, P35, DOI 10.1586/14789450.2016.1122528
NR 40
TC 14
Z9 20
U1 0
U2 11
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR
PY 2021
VL 29
IS 2
BP 288
EP 297
DI 10.1111/wrr.12887
EA DEC 2020
PG 10
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA QR8SI
UT WOS:000603165100001
PM 33374033
DA 2026-07-24
ER

PT J
AU Scherer, SS
   Pietramaggiori, G
   Mathews, JC
   Orgill, DP
AF Scherer, Sandra Saja
   Pietramaggiori, Giorgio
   Mathews, Jasmine C.
   Orgill, Dennis P.
TI Short Periodic Applications of the Vacuum-Assisted Closure Device Cause
   an Extended Tissue Response in the Diabetic Mouse Model
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID SUBATMOSPHERIC PRESSURE; CLINICAL-EXPERIENCE; CHRONIC WOUNDS;
   ANGIOGENESIS; THERAPY; SWINE
AB Background: The vacuum-assisted closure device is a widely used mechanical modulator of wound healing; however, the optimal time kinetics of application have not been determined. The objective of the study was to optimize the kinetics of vacuum-assisted closure application.
   Methods: Full-thickness wounds in seven diabetic mice per study group were treated with either an occlusive dressing alone, the vacuum-assisted closure device for 6 or 12 hours, or the vacuum-assisted closure device periodically for 4 hours every other day or continuously for 7 days. Wound closure and tissue response were evaluated by macroscopic, histologic, and immunohistochemical analyses on day 7.
   Results: Wound closure was significantly faster after short initial vacuum-assisted closure (6-hour and 12-hour groups) when compared with continuous treatment. Increased granulation tissue formation was seen in the 12-hour group (2.4-fold increase) and in those treated periodically for 4 hours every other day (3.2-fold increase) compared with the dressing-alone controls. Significant stimulation of cell proliferation was seen after all vacuum-assisted closure patterns (3.6- to 5.3-fold increase), whereas angiogenesis was augmented only after the device was applied for either three times for 4 hours (4.3-fold) or continuously (4.7-fold) when compared with dressing-treated wounds. Treatment three times for 4 hours showed a superior angiogenic effect also when compared with short initial applications (6-hour and 12-hour groups).
   Conclusions: Short vacuum-assisted closure treatment induced an extended biological response in the wound. A total of 12 hours of periodically applied vacuum-assisted closure reached a similar wound tissue response as continuously applied vacuum-assisted closure for 7 days. These findings suggest new clinical approaches for mechanical wound-healing devices. (Plast. Reconstr. Surg. 124: 1458, 2009.)
C1 [Orgill, Dennis P.] Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, Boston, MA 02115 USA.
   Univ Hosp Geneva, Dept Surg, Geneva, Switzerland.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard Medical School; University of Geneva
RP Orgill, DP (通讯作者)，Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
EM dorgill@partners.org
RI PIETRAMAGGIORI, Giorgio/HJA-1920-2022; Orgill, Dennis/H-7596-2019
OI Orgill, Dennis/0000-0002-8279-7310
CR Ahroni JH, 1999, DIABETES CARE, V22, P965, DOI 10.2337/diacare.22.6.965
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   Zheng W, 2008, AM J PHYSIOL-HEART C, V295, pH794, DOI 10.1152/ajpheart.00343.2008
NR 23
TC 36
Z9 43
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD NOV
PY 2009
VL 124
IS 5
BP 1458
EP 1465
DI 10.1097/PRS.0b013e3181bbc829
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 515ZZ
UT WOS:000271512700012
PM 20009831
DA 2026-07-24
ER

PT J
AU Yuan, L
   Sun, YY
   Yan, JJ
AF Yuan, Ling
   Sun, Yingying
   Yan, Jianjun
TI Case Report: A case of Fournier's gangrene of the scrotum
SO FRONTIERS IN MEDICINE
LA English
DT Article
DE Fournier's gangrene; necrotizing fasciitis; soft tissue infection;
   vacuum sealing drainage; wound managemen
AB A 68-year-old man with poorly controlled type 2 diabetes and untreated stage 2 hypertension presented with a 7-day history of painful scrotal and perianal swelling. Imaging revealed subcutaneous gas and necrotic sinus tracts, and tissue cultures showed a polymicrobial infection. Fournier's gangrene was diagnosed. Prompt surgical debridement, vacuum sealing drainage (VSD), glycemic control, and antibiotic therapy led to complete recovery, highlighting the importance of early recognition and aggressive management.
C1 [Yuan, Ling; Sun, Yingying; Yan, Jianjun] Shandong First Med Univ, Shandong Prov Hosp, Dept Dermatol, Jinan, Shandong, Peoples R China.
C3 Shandong First Medical University & Shandong Academy of Medical Sciences
RP Yan, JJ (通讯作者)，Shandong First Med Univ, Shandong Prov Hosp, Dept Dermatol, Jinan, Shandong, Peoples R China.
EM jianjun19870103@163.com
CR Chokshi A, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.44383
   Czymek R, 2013, COLORECTAL DIS, V15, P1529, DOI 10.1111/codi.12396
   Fernando SM, 2019, ANN SURG, V269, P58, DOI [10.1097/sla.0000000000002774, 10.1097/SLA.0000000000002774]
   Hagedorn JC, 2017, NAT REV UROL, V14, P205, DOI 10.1038/nrurol.2016.243
   Kopechek KJ, 2025, CURR UROL REP, V26, DOI 10.1007/s11934-025-01275-3
   Leiblein M, 2020, ORTHOP SURG, V12, P1733, DOI 10.1111/os.12804
   Mao TC, 2022, BMC UROL, V22, DOI 10.1186/s12894-022-00975-z
   Nayyar C, 2025, ARCH MED HEALTH SCI, DOI [10.4103/amhs.amhs_219_24, 10.4103/amhs.amhs_219_24, DOI 10.4103/AMHS.AMHS_219_24]
   Tuncel A, 2006, EUR UROL, V50, P838, DOI 10.1016/j.eururo.2006.01.030
NR 9
TC 0
Z9 0
U1 0
U2 0
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
EI 2296-858X
J9 FRONT MED-LAUSANNE
JI Front. Med.
PD APR 8
PY 2026
VL 13
AR 1791234
DI 10.3389/fmed.2026.1791234
EA APR 2026
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GU3RV
UT WOS:001745260500001
PM 42027829
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Fujii, Y
   Tajima, Y
   Kaji, S
   Kishi, T
   Miyazaki, Y
   Taniura, T
   Hirahara, N
AF Fujii, Yusuke
   Tajima, Yoshitsugu
   Kaji, Shunsuke
   Kishi, Takashi
   Miyazaki, Yoshiko
   Taniura, Takahito
   Hirahara, Noriyuki
TI Complete abdominal wound and anastomotic leak with diffuse peritonitis
   closure achieved by an abdominal vacuum sealing drainage in a critical
   ill patient: a case report
SO BMC SURGERY
LA English
DT Article
DE Anastomotic leakage; Peritonitis; Wound dehiscence; Negative pressure
   wound therapy
ID ENTEROCUTANEOUS FISTULAS; ASSISTED CLOSURE; MANAGEMENT
AB Background: Negative pressure wound therapy (NPWT) is a widely accepted technique to treat local infectious wounds of the skin, subcutaneous tissue, fascia, or muscle. Recently, several reports describing the efficacy of NPWT for various types of fistulas and anastomotic leaks have been published. We herein describe a patient with an open abdominal wound due to colonic anastomotic leakage and diffuse peritonitis, in whom abdominal vacuum sealing (AVS) as a modified NPWT was useful for the management of this complex wound.
   Case presentation: A 32-year-old man was admitted to our hospital with late presenting traumatic diaphragmatic hernia and strangulated ileum complicated by necrosis of the ileum and transverse colon. He had a history of cervical spinal cord injury due to suicide attempt 14 years earlier and, as a result of cervical spinal cord injury, he was paralyzed in the lower body. The patient underwent an urgent hernia repair and bowel resection. Postoperatively, he developed severe septic shock On postoperative day (POD) 6, wound dehiscence due to colonic anastomotic leakage with diffuse peritonitis was diagnosed, but he was unable to undergo re-operation because of refractory severe septic shock combined with neurogenic shock due to the cervical cord injury. The patient was treated with AVS therapy. He gradually recovered from septic shock, and the anastomotic leakage healed after a 2-month period. The wound dehiscence was also reduced. The patient resumed oral intake on POD 112 and was discharged on POD 190.
   Conclusions: Although surgical repair would be the best method for the treatment of diffuse peritonitis due to gastrointestinal perforation or anastomotic leakage, our case suggests that AVS with 'conventional' drainage is a treatment of choice for open abdominal wounds even in the presence of diffuse peritonitis caused by intestinal anastomotic leakage, especially in patients with poor general medical condition.
C1 [Fujii, Yusuke; Tajima, Yoshitsugu; Kaji, Shunsuke; Kishi, Takashi; Miyazaki, Yoshiko; Taniura, Takahito; Hirahara, Noriyuki] Shimane Univ, Fac Med, Dept Digest & Gen Surg, 89-1 Enyacho, Izumo, Shimane 6938501, Japan.
C3 Shimane University
RP Fujii, Y (通讯作者)，Shimane Univ, Fac Med, Dept Digest & Gen Surg, 89-1 Enyacho, Izumo, Shimane 6938501, Japan.
EM yuusuke@med.shimane-u.ac.jp
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 14
TC 4
Z9 5
U1 0
U2 7
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1471-2482
J9 BMC SURG
JI BMC Surg.
PD JUN 15
PY 2018
VL 18
AR 41
DI 10.1186/s12893-018-0375-6
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GJ5GN
UT WOS:000435409600001
PM 29907107
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Küçük, E
   Akilli, AF
   Ordulu, R
   Sengül, M
   Kayhan, ME
   Akdeniz, E
   Ulubay, M
   Atilla, MK
AF Kucuk, Emrah
   Akilli, Ahmet Furkan
   Ordulu, Reha
   Sengul, Mesut
   Kayhan, Muhammed Esad
   Akdeniz, Ekrem
   Ulubay, Mahmut
   Atilla, Mustafa Kemal
TI Outcomes of vacuum-assisted closure therapy (VAC) in patients with
   Fournier's gangrene: a retrospective cohort study
SO IRISH JOURNAL OF MEDICAL SCIENCE
LA English
DT Article; Early Access
DE Debridement; Fournier's gangrene; Vacuum-assisted closure
ID PRESSURE WOUND THERAPY; SKIN-GRAFT
AB Objective To evaluate the association between vacuum-assisted closure therapy and clinical outcomes, particularly mortality, in patients surgically treated for Fournier's gangrene. Methods This retrospective cohort study included 268 patients treated for Fournier's gangrene between 2015 and 2025. Patients were divided into two groups: debridement alone (Group 1, n = 160) and debridement plus vacuum-assisted closure therapy (Group 2, n = 108). Demographic characteristics, comorbidities, laboratory findings, Fournier Gangrene Severity Index, intensive care unit admission, additional surgical procedures, length of stay, and mortality were compared. Multivariate logistic regression was performed to identify independent predictors of mortality. Results Observed mortality was lower in the vacuum-assisted closure therapy group than in the debridement-only group (7.4% vs. 16.9%, p = 0.038). However, multivariate analysis demonstrated that only intensive care unit admission (OR 6.40, 95% CI 1.52-26.89, p = 0.011) and Fournier Gangrene Severity Index score (OR 5.57, 95% CI 2.91-10.71, p < 0.001) were independently associated with mortality. Vacuum-assisted closure therapy was not an independent predictor (OR 0.58, 95% CI 0.16-2.10, p = 0.409). The vacuum-assisted closure therapy group underwent more debridement procedures and had a longer hospital stay. Conclusion Although vacuum-assisted closure therapy was associated with lower unadjusted mortality, survival was primarily determined by disease severity and intensive care unit admission. Vacuum-assisted closure therapy may improve wound management; however, its impact on survival appears influenced by baseline clinical status. Prospective studies are needed to clarify its role in Fournier's gangrene management.
C1 [Kucuk, Emrah; Akilli, Ahmet Furkan; Akdeniz, Ekrem; Ulubay, Mahmut; Atilla, Mustafa Kemal] Samsun Univ, Fac Med, Dept Urol, Samsun, Turkiye.
   [Ordulu, Reha; Sengul, Mesut; Kayhan, Muhammed Esad] Samsun City Hosp, Urol Clin, Samsun, Turkiye.
C3 Samsun University
RP Küçük, E (通讯作者)，Samsun Univ, Fac Med, Dept Urol, Samsun, Turkiye.
EM emrah.kucuk@samsun.edu.tr
RI Atilla, Mustafa/NEU-6329-2025
FU Samsun University
FX Open access funding provided by the Scientific and Technological
   Research Council of Turkiye (TUB & Idot;TAK).
CR Altomare M, 2022, J PERS MED, V12, DOI 10.3390/jpm12101695
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NR 27
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER LONDON LTD
PI LONDON
PA 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND
SN 0021-1265
EI 1863-4362
J9 IRISH J MED SCI
JI Irish J. Med. Sci.
PD 2026 APR 27
PY 2026
DI 10.1007/s11845-026-04416-w
EA APR 2026
PG 8
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA HE2AZ
UT WOS:001751930500001
PM 42043476
OA hybrid
DA 2026-07-24
ER

PT J
AU Chen, YE
   Gerstle, T
   Verma, K
   Treiser, MD
   Kimball, AB
   Orgill, DP
AF Chen, Y. Erin
   Gerstle, Theodore
   Verma, Kapil
   Treiser, Matthew D.
   Kimball, Alexandra B.
   Orgill, Dennis P.
TI Management of Hidradenitis Suppurativa Wounds with an Internal Vacuum-
   Assisted Closure Device
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID SUBATMOSPHERIC PRESSURE; DOUBLE-BLIND; THERAPY; EXCISION; GRANULATION;
   BRIDGE
AB Background: Hidradenitis suppurativa is a chronic, debilitating disease that is difficult to treat. Once medical management fails, wide local excision offers the best chance for cure. However, the resultant wound often proves too large or contaminated for immediate closure.
   Methods: The authors performed a retrospective chart review of hidradenitis cases managed surgically between 2005 and 2010. Data collected included patient characteristics, management method, and outcomes. Approximately half of the patients received internal vacuum-assisted closure therapy using the vacuum-assisted closure system and delayed closure and half of the patients received immediate primary closure at the time of their excision. Delayed closure consisted of closing the majority of the wound in a linear fashion following internal vacuum-assisted closure while accepting healing by means of secondary intention for small wound areas.
   Results: Patients managed with internal vacuum-assisted closure had wounds on average four times larger in area than patients managed without internal vacuum-assisted closure. In both groups, all wounds were eventually closed primarily. Healing times averaged 2.2 months with internal vacuum-assisted closure and 2.7 months without. At an average follow-up time of 2.3 months, all patients with internal vacuum-assisted closure had no recurrence of their local disease.
   Conclusions: Severe hidradenitis presents a treatment challenge, as surgical excisions are often complicated by difficult closures and unsatisfactory recurrence rates. This study demonstrates that wide local excision with reasonable outcomes can be achieved using accelerated delayed primary closure. This method uses internal vacuum-assisted closure as a bridge between excision and delayed primary closure, facilitating closure without recurrence in large, heavily contaminated wounds.
   CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.
C1 Beth Israel Deaconess Med Ctr, Dept Med, New York, NY 10003 USA.
   Brigham & Womens Hosp, Div Plast Surg, Boston, MA 02115 USA.
   Georgetown Univ Hosp, Dept Plast Surg, Washington, DC USA.
   Massachusetts Gen Hosp, Dept Dermatol, Boston, MA 02114 USA.
C3 Harvard University; Harvard University Medical Affiliates; Beth Israel
   Deaconess Medical Center; Harvard University; Harvard University Medical
   Affiliates; Brigham & Women's Hospital; Georgetown University; Harvard
   University; Harvard University Medical Affiliates; Massachusetts General
   Hospital
RP Orgill, DP (通讯作者)，75 Francis St, Boston, MA 02115 USA.
EM dorgill@partners.org
RI Orgill, Dennis/H-7596-2019; Kimball, Alexana/M-6347-2019
OI Kimball, Alexana/0000-0001-9405-0479; Chen, Yiyin
   Erin/0000-0001-9452-1402; Verma, Kapil Dev/0000-0002-1163-2535
FU Kinetic Concepts, Inc.
FX Dr. Orgill has been an expert witness, consultant, and grant recipient
   of funding provided by Kinetic Concepts, Inc., the manufacturer of the
   V.A.C. devices mentioned in this article. The remaining authors have no
   financial interests to disclose.
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NR 36
TC 38
Z9 43
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD MAR
PY 2014
VL 133
IS 3
BP 370E
EP 377E
DI 10.1097/PRS.0000000000000080
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AD4TN
UT WOS:000333243600017
PM 24572882
DA 2026-07-24
ER

PT J
AU Vos, RJ
   Yilmaz, A
   Sonker, U
   Kloppenburg, GTL
AF Vos, Roemer J.
   Yilmaz, Alaaddin
   Sonker, Uday
   Kloppenburg, Geoffrey T. L.
TI Acute mediastinal bleeding during vacuum-assisted closure
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Bleeding; Complication; Mediastinitis; Vacuum-assisted closure
ID POSTSTERNOTOMY MEDIASTINITIS; SURGERY
AB Vacuum-assisted closure is commonly used to treat post-sternotomy mediastinitis. Several studies show improved outcome using vacuum-assisted therapy; however, risks using negative pressure should not be underestimated. We describe two cases of acute mediastinal bleeding during vacuum treatment for post-sternotomy mediastinitis and discuss preventative measurements.
C1 [Vos, Roemer J.; Yilmaz, Alaaddin; Sonker, Uday; Kloppenburg, Geoffrey T. L.] St Antonius Hosp, Dept Cardiothorac Surg, NL-3435 CM Nieuwegein, Netherlands.
C3 St. Antonius Hospital Utrecht
RP Kloppenburg, GTL (通讯作者)，St Antonius Hosp, Dept Cardiothorac Surg, Koekoekslaan 1, NL-3435 CM Nieuwegein, Netherlands.
EM geoffrey_kloppenburg@hotmail.com
OI Vos, Roemer/0000-0002-2511-988X
CR Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   Ennker IC, 2011, THORAC CARDIOV SURG, V59, P15, DOI 10.1055/s-0030-1250335
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   Sartipy U, 2006, ANN THORAC SURG, V82, P1110, DOI 10.1016/j.athoracsur.2006.01.060
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjögren J, 2005, ANN THORAC SURG, V80, P1270, DOI 10.1016/j.athoracsur.2005.04.010
NR 8
TC 5
Z9 6
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2013
VL 10
IS 3
BP 348
EP 350
DI 10.1111/j.1742-481X.2012.00989.x
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 146CF
UT WOS:000319065700020
PM 22630562
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Sjögren, J
   Gustafsson, R
   Nilsson, J
   Malmsjö, M
   Ingemansson, R
AF Sjögren, J
   Gustafsson, R
   Nilsson, J
   Malmsjö, M
   Ingemansson, R
TI Clinical outcome after poststernotomy mediastinitis: Vacuum-assisted
   closure versus conventional treatment
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID STERNAL WOUND-INFECTION; POSTOPERATIVE MEDIASTINITIS; FLAP
   RECONSTRUCTION; SUCTION DRAINAGE; MUSCLE FLAPS; RISK-FACTORS;
   STERNOTOMY; MANAGEMENT; SURGERY; IRRIGATION
AB Background. The conventional treatment for poststernotomy mediastinitis usually involves surgical revision, closed irrigation, or reconstruction with omentum or pectoral muscle flaps. Recently, vacuum-assisted closure has been successfully used in poststernotomy mediastinitis. The aim of the present study was to compare the clinical outcome and survival in 101 patients undergoing vacuum-assisted closure therapy or conventional treatment for poststernotomy mediastinitis.
   Methods. One hundred one consecutive patients underwent treatment for poststernotomy mediastinitis: vacuum-assisted closure therapy (January 1999 through December 2003, n = 61) or conventional treatment (July 1994 through December 1998, n = 40). Follow-up was made in April 2004 and was 100% complete. Actuarial statistics were used to calculate the survival rates.
   Results. The 90-days mortality was 0% in the vacuum-assisted closure group and 15% in the conventional treatment group (p < 0.01). The failure rate to first-line treatment with vacuum-assisted closure and conventional treatment were 0% and 37.5%, respectively (p < 0.001). There was no statistically significant difference in the recurrence of sternal fistulas after vacuum-assisted closure therapy or conventional treatment: 6.6% versus 5.0%, respectively. Overall survival in the vacuum-assisted closure group was significantly better (p < 0.05) than in the conventional treatment group: 97% versus 84% (6 months), 93% versus 82% (1 year), and 83% versus 59% (5 years).
   Conclusions. Our findings support that vacuum-assisted closure therapy is a safe and reliable option in poststernotomy mediastinitis with excellent survival and a very low failure rate compared with conventional treatment. (c) 2005 by The Society of Thoracic Surgeons.
C1 Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, SE-22185 Lund, Sweden.
   Univ Lund Hosp, Dept Internal Med, SE-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital
RP Sjögren, J (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, SE-22185 Lund, Sweden.
EM johan.sjogren@thorax.lu.se
RI Sjögren, Johan/AAZ-6448-2021; Nilsson, Johan/A-4742-2011
OI Nilsson, Johan/0000-0001-6860-6090; Ingemansson,
   Richard/0000-0001-7623-8953; Maljö, Malin/0000-0001-9849-9599
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NR 34
TC 158
Z9 176
U1 0
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD JUN
PY 2005
VL 79
IS 6
BP 2049
EP 2055
DI 10.1016/j.athoracsur.2004.12.048
PG 7
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 931YJ
UT WOS:000229521100036
PM 15919308
DA 2026-07-24
ER

PT J
AU Hurnburg, J
   Holzgreve, W
   Hoesli, I
AF Humburg, Joerg
   Holzgreve, Wolfgang
   Hoesli, Irene
TI Negative pressure wound therapy in post-cesarean superficial wound
   disruption: A report of 3 cases
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID CESAREAN DELIVERY; CLOSURE
AB Wound disruption after cesarean section is a common complication that may cause additional stress postpartum. The treatment options are secondary closure with the risk of reinfection or healing by secondary intention. In some cases, negative pressure wound therapy can be a useful alternative. Three cases of superficial wound disruption after cesarean section performed for failure to progress are presented. Successful closure with negative pressure wound therapy was achieved after conventional surgical treatment options were exhausted or unacceptable to the patients. Negative pressure wound therapy is a safe, feasible, and well-tolerated treatment option.
C1 Univ Womens Hosp, Dept Obstet & Gynaecol, CH-4031 Basel, Switzerland.
RP Hurnburg, J (通讯作者)，Univ Womens Hosp, Dept Obstet & Gynaecol, Spitalstr 21, CH-4031 Basel, Switzerland.
EM jhumburg@uhbs.ch
CR Chelmow D, 2004, OBSTET GYNECOL, V103, P974, DOI 10.1097/01.AOG.0000124807.76451.47
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   WALTERS MD, 1990, OBSTET GYNECOL, V76, P597
NR 6
TC 6
Z9 6
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUN
PY 2006
VL 18
IS 6
BP 166
EP 169
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 061FY
UT WOS:000238857900006
DA 2026-07-24
ER

PT J
AU Ford-Dunn, S
AF Ford-Dunn, Suzanne
TI Use of vacuum assisted closure therapy in the palliation of a malignant
   wound
SO PALLIATIVE MEDICINE
LA English
DT Article
DE malignant wound; palliative care; vacuum assisted closure
ID DEVICE
AB Vacuum assisted closure (VAC) therapy is a novel method of wound healing using topical negative pressure across the wound bed and containing all exudate within a sealed system. We report the use of VAC therapy to control pain and exudate of a malignant wound.
C1 St Barnabas Hosp, Columbia Dr, Worthing, England.
RP Ford-Dunn, S (通讯作者)，St Barnabas Hosp, Columbia Dr, Worthing, England.
EM suzanne.ford.dunn@stbarnabas-hospice.org.uk
OI Ford-Dunn, Suzanne/0009-0003-4444-421X
CR Banwell P E, 1999, J Wound Care, V8, P79
   de Geus HRH, 2005, INTENS CARE MED, V31, P601, DOI 10.1007/s00134-004-2553-5
   Eginton MT, 2003, ANN VASC SURG, V17, P645, DOI 10.1007/s10016-003-0065-3
   Miller M., 1999, Wound Management: Theory And Practice
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Schaffzin DM, 2004, DIS COLON RECTUM, V47, P1745, DOI 10.1007/s10350-004-0633-9
   SMITH N, 2005, BR J NURS, V13, P1359
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Stonerock CE, 2003, AM SURGEON, V69, P1030
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
NR 11
TC 24
Z9 29
U1 0
U2 2
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 0269-2163
EI 1477-030X
J9 PALLIATIVE MED
JI Palliat. Med.
PY 2006
VL 20
IS 4
BP 477
EP 478
DI 10.1191/0269216306pm1117cr
PG 2
WC Health Care Sciences & Services; Public, Environmental & Occupational
   Health; Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services; Public, Environmental & Occupational
   Health; General & Internal Medicine
GA 055GN
UT WOS:000238438300013
PM 16875120
DA 2026-07-24
ER

PT J
AU Ben, D
   Li, T
   Xia, Z
AF Ben, D.
   Li, T.
   Xia, Z.
TI Free dermatoplasty combining with vacuum sealing drainage with or
   without Pelnac used for the treatment of extensive follicular occulusion
   triad in the gluteal and perianal regions
SO JOURNAL OF INVESTIGATIVE DERMATOLOGY
LA English
DT Meeting Abstract
CT Annual Meeting of the Society-for-Investigative-Dermatology (SID)
CY MAY 07-10, 2014
CL Albuquerque, NM
SP Soc Invest Dermatol
C1 [Ben, D.; Li, T.; Xia, Z.] Changhai Hosp, Dept Burn & Trauma Surg, Shanghai, Peoples R China.
C3 Naval Medical University
RI D, Dhanya/ABH-2769-2021
NR 0
TC 2
Z9 2
U1 0
U2 4
PU NATURE PUBLISHING GROUP
PI NEW YORK
PA 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA
SN 0022-202X
EI 1523-1747
J9 J INVEST DERMATOL
JI J. Invest. Dermatol.
PD MAY
PY 2014
VL 134
SU 1
MA 515
BP S90
EP S90
PG 1
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Dermatology
GA AF2RT
UT WOS:000334560400514
DA 2026-07-24
ER

PT J
AU Lambert, KV
   Hayes, P
   McCarthy, M
AF Lambert, KV
   Hayes, P
   McCarthy, M
TI Vacuum assisted closure: A review of development and current
   applications
SO EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
LA English
DT Review
DE vacuum assisted closure; topical negative pressure; vacuum sealing
   technique; sub-atmospheric pressure; dressings; wound management; acute
   wounds; chronic wounds
ID TOPICAL NEGATIVE-PRESSURE; SUBATMOSPHERIC PRESSURE; WOUND CONTROL;
   THERAPY; DEVICE; TRIAL
AB Vacuum assisted closure is being increasingly used for wound management. This review examines the history of its development and appraises the current evidence on its use so far.
C1 Univ Leicester, Vasc Surg Res Grp, Div Cardiovasc Sci, Leicester LE2 7ES, Leics, England.
C3 University of Leicester
RP Lambert, KV (通讯作者)，Univ Leicester, Vasc Surg Res Grp, Div Cardiovasc Sci, Robert Kilpatrick Bldg,Infirm Sq, Leicester LE2 7ES, Leics, England.
EM kellylambert@hotmail.com; paul.hayes@easynet.net.uk; lmcc30@aol.co.uk
CR Alvarez AA, 2001, GYNECOL ONCOL, V80, P413, DOI 10.1006/gyno.2000.6092
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NR 42
TC 126
Z9 157
U1 0
U2 14
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 1078-5884
EI 1532-2165
J9 EUR J VASC ENDOVASC
JI Eur. J. Vasc. Endovasc. Surg.
PD MAR
PY 2005
VL 29
IS 3
BP 219
EP 226
DI 10.1016/j.ejvs.2004.12.017
PG 8
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA 903KR
UT WOS:000227425200001
PM 15694791
DA 2026-07-24
ER

PT J
AU Chen, QL
   Lu, MT
   Liu, XY
   Yu, YM
   Li, JY
AF Chen, Qingling
   Lu, Minting
   Liu, Xueyan
   Yu, Yanmei
   Li, Jiaying
TI Comparison of customized vacuum sealing drainage and vacuum sealing
   drainage in the treatment of diabetic foot ulcers: a retrospective
   analysis
SO JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
LA English
DT Article
DE Diabetic foot ulcers; Vacuum sealing drainage; Customized vacuum sealing
   drainage; Retrospective analysis
ID C-PEPTIDE
AB Background The prevalence of diabetic foot ulcers, a common, more serious chronic diabetes-related complication, is increasing. Vacuum sealing drainage (VSD) constitutes an effective adjunctive treatment for diabetic foot ulcers. Factors, such as poor glycemic control, ischemia, and infection prolong wound healing time, and VSD products are expensive and unaffordable for many patients.ObjectiveTo compare the use of customized VSD and customized VSD in the treatment of diabetic foot ulcer.Method This retrospective study included 83 patients with diabetic foot ulcers in customized VSD (n = 44) and VSD (n = 39) groups. Baseline data, efficacy after 14 days, total treatment efficiency, final outcome (28 days after treatment, healing rate), average treatment cost, and hospitalization (days) of the two groups were compared. Factors affecting wound healing were analyzed.Results No significant intergroup differences in the baseline data were detected (VSD vs. customized VAD, p > 0.05). Treatment efficacy was higher in the customized VSD group than in the VSD group after 14 days (p < 0.05), although total treatment efficiency in both groups reached 100%. The final outcome in the customized VSD group was better (vs. VSD group, p < 0.05), and the wound healing rate was higher than in the VSD group (66.7% vs. 33.3%). The mean treatment cost and hospital days were greater in the VSD group (vs. customized VSD group; p < 0.05). Factors affecting wound healing include age, Wagner classification, HDL-C, and fasting C-peptide. Younger age, low Wagner classification grade, low HDL-C level, and high fasting C-peptide contribute to higher healing rate,Conclusion Efficacy and final outcome of customized VSD were better than that of VSD; the customized VSD device is simple and convenient to operate, and enables cost-effective treatment.
C1 [Chen, Qingling; Li, Jiaying] Jinan Univ, Affiliated Hosp 1, Dept Endocrinol, Guangzhou 510632, Peoples R China.
   [Lu, Minting] Jinan Univ, Sch Nursing, Guangzhou 510632, Peoples R China.
   [Liu, Xueyan; Yu, Yanmei] Jinan Univ, Affiliated Hosp 1, Dept Endocrinol & Metab, Guangzhou 510632, Peoples R China.
C3 Jinan University; Jinan University; Jinan University
RP Li, JY (通讯作者)，Jinan Univ, Affiliated Hosp 1, Dept Endocrinol, Guangzhou 510632, Peoples R China.
EM cqingling0718@163.com
FU This study was supported by the First Hospital Affiliated of Jinan
   University. We are grateful to all the healthcare professionals who
   provided support and assistance in this study.; First Hospital
   Affiliated of Jinan University
FX This study was supported by the First Hospital Affiliated of Jinan
   University. We are grateful to all the healthcare professionals who
   provided support and assistance in this study.
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NR 39
TC 5
Z9 6
U1 0
U2 11
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-799X
J9 J ORTHOP SURG RES
JI J. Orthop. Surg. Res.
PD OCT 27
PY 2023
VL 18
IS 1
AR 803
DI 10.1186/s13018-023-04298-z
PG 8
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA X1MW3
UT WOS:001096166700001
PM 37891685
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Zhang, P
   Tao, FL
   Li, QH
   Zhou, DS
   Liu, FX
AF Zhang, Peng
   Tao, Fu-Lin
   Li, Qing-Hu
   Zhou, Dong-Sheng
   Liu, Fan-Xiao
TI Salvage of vascular graft infections via vacuum sealing drainage
   and rectus femoris muscle flap transposition: A case report
SO WORLD JOURNAL OF CLINICAL CASES
LA English
DT Article
DE Vascular graft; Infection; Muscle flap transposition; Rectus femoris
   muscle flap; Vacuum sealing drainage; Case report; Trauma
AB BACKGROUND
   The management of vascular graft infections continues to be a significant challenge in a clinical situation. The aim of this report is to illustrate the novel vacuum sealing drainage (VSD) technique and rectus femoris muscle flap transposition for vascular graft infections, and to evaluate the prospective of future testing of this surgical procedure.
   CASE SUMMARY
   We report the case of a 32-year-old male patient, who presented a severe infected groin wound with biological vascular graft Acinetobacter baumannii infection resulting in extensive graft exposure. Using the VSD and muscle flap trans-position, the groin wound and vascular graft infection were finally treated successfully.
   CONCLUSION
   Our case report highlights that VSD technique and rectus femoris muscle flap transposition could be considered in patients presenting with a severe infected groin wound with biological vascular graft Acinetobacter baumannii infection resulting in extensive graft exposure, especially in consideration of treatable conditions.
C1 [Zhang, Peng; Tao, Fu-Lin; Li, Qing-Hu; Zhou, Dong-Sheng; Liu, Fan-Xiao] Shandong First Med Univ, Dept Orthopaed, Shandong Prov Hosp, 324 Qingwuweigi Rd, Jinan 250021, Shandong, Peoples R China.
C3 Shandong First Medical University & Shandong Academy of Medical Sciences
RP Liu, FX (通讯作者)，Shandong First Med Univ, Dept Orthopaed, Shandong Prov Hosp, 324 Qingwuweigi Rd, Jinan 250021, Shandong, Peoples R China.
EM woshi631@126.com
RI Liu, Fanxiao/U-1513-2019
FU Shandong Provincial Natural Science Foundation [ZR2013HM069]; Shandong
   Key RD Program [2017GSF218089]; China Scholarship Council [201808080126]
FX Supported by Shandong Provincial Natural Science Foundation, No.
   ZR2013HM069; Shandong Key R&D Program, No. 2017GSF218089; and China
   Scholarship Council, No. 201808080126.
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NR 18
TC 2
Z9 4
U1 0
U2 4
PU BAISHIDENG PUBLISHING GROUP INC
PI PLEASANTON
PA 7041 Koll Center Parkway, Suite 160, PLEASANTON, CA, UNITED STATES
SN 2307-8960
J9 WORLD J CLIN CASES
JI World J. Clin. Cases
PD APR 6
PY 2021
VL 9
IS 10
BP 2296
EP 2301
DI 10.12998/wjcc.v9.i10.2296
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA RM1UO
UT WOS:000639445700015
PM 33869606
OA Green Accepted, gold
DA 2026-07-24
ER

PT J
AU Derrick, KL
   Lessing, C
   Allen, D
   James, R
   Ingram, S
AF Derrick, K. L.
   Lessing, C.
   Allen, D.
   James, R.
   Ingram, S.
TI GRANULATION RESPONSE OF NEGATIVE PRESSURE WOUND THERAPY WITH
   INSTILLATION INCLUDES GENE EXPRESSION VARIATIONS WHILE MAINTAINING
   TISSUE QUALITY COMPARED TO CONTINUOUS AND NONCONTINUOUS NEGATIVE
   PRESSURE WOUND THERAPY IN A PORCINE MODEL
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Derrick, K. L.; Lessing, C.; Allen, D.; James, R.; Ingram, S.] Kinet Concepts Inc, San Antonio, TX USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR
PY 2014
VL 22
IS 2
BP A37
EP A37
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA AC9DV
UT WOS:000332835400043
DA 2026-07-24
ER

PT J
AU Tang, XH
   Chen, C
   Liu, YD
   Qiao, XF
   Liu, H
   Ma, ZM
   Zhu, JM
   Liu, JJ
AF Tang, Xiao-Huan
   Chen, Chao
   Liu, Yuan-Da
   Qiao, Xiao-Fang
   Liu, Hao
   Ma, Zhi-Ming
   Zhu, Jia-Ming
   Liu, Jing-Jing
TI A rare postoperative complication of perforated appendicitis:
   necrotizing fasciitis
SO INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
LA English
DT Article
DE Necrotizing fasciitis; perforated appendicitis; postoperative
   complication; lumbar triangles; vacuum sealing drainage
AB Perforated appendicitis is a type of acute appendicitis with a morbidity rate of 15.8%. In addition, potentially fatal postoperative complications associated with laparoscopic appendectomy for perforated appendicitis may occur with wound infections comprising 15.2% of such complications. Herein we report a case in which a 35-yearold woman presented with acute appendicitis in the clinic. After failure with conservative treatment, laparoscopic appendectomy was performed. Five days after the operation, the patient developed necrotizing fasciitis which was then treated with surgical debridement. After ten days of conservative treatment with intravenous antibiotics and forty days of modified vacuum sealing drainage, the patient attained full recovery. This case represents a potentially fatal postoperative complication of perforated appendicitis which is especially rare. Retroperitoneal inflammation and/or abscesses may cause necrotizing fasciitis through lumbar triangles, which are two weak areas in the loin. Therefore, modified vacuum sealing drainage is a simple and effective treatment to treat necrotizing fasciitis.
C1 [Tang, Xiao-Huan; Chen, Chao; Liu, Yuan-Da; Qiao, Xiao-Fang; Liu, Hao; Ma, Zhi-Ming; Zhu, Jia-Ming; Liu, Jing-Jing] Jilin Univ, Dept Gastrointestinal Nutr & Hernia Surg, Hosp 2, 218 Zigiang St, Changchun 130041, Jilin, Peoples R China.
C3 Jilin University
RP Zhu, JM; Liu, JJ (通讯作者)，Jilin Univ, Dept Gastrointestinal Nutr & Hernia Surg, Hosp 2, 218 Zigiang St, Changchun 130041, Jilin, Peoples R China.
EM Zhujiaming75@sina.com; jingjingstarone@163.com
RI Zhu, Jiaming/OJZ-8196-2025; Tang, xiaohuan/HGT-7031-2022
FU Research Fund of Health and Family Plan-ning Commission of Jilin
   Province [2016C0543]
FX We thank the Department of Imaging, the Second Hospital of Jilin
   University for the CT's pictures provided. This study was supported by
   the Research Fund of Health and Family Plan-ning Commission of Jilin
   Province (2016C0543). Informed consent was obtained from the patients in
   this study and approval for these studies was obtained through the
   institutional Ethics Committee.
CR Beerle Corinne, 2016, J Med Case Rep, V10, P331, DOI 10.1186/s13256-016-1122-1
   Drake FT, 2014, JAMA SURG, V149, P837, DOI 10.1001/jamasurg.2014.77
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   Takeda M, 2012, SURG TODAY, V42, P781, DOI 10.1007/s00595-012-0140-x
NR 14
TC 2
Z9 2
U1 0
U2 3
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1940-5901
J9 INT J CLIN EXP MED
JI Int. J. Clin. Exp. Med.
PY 2018
VL 11
IS 9
BP 10126
EP 10130
PG 5
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA GY8AL
UT WOS:000448839700158
DA 2026-07-24
ER

PT J
AU Cheng, H
   Li, XJ
   Li, XY
   Bai, Y
   Zhang, W
   Zhao, B
   Yang, T
   Li, P
   Yao, WD
AF Cheng, Hui
   Li, Xiaojing
   Li, Xinyi
   Bai, Yun
   Zhang, Wei
   Zhao, Boao
   Yang, Tao
   Li, Ping
   Yao, Wende
TI Extensive Nevus Comedonicus Treated by Comb Flap Reconstruction, Super
   Tension-Relieving Sutures, and Vacuum Sealing Drainage: A Case Report
SO CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
LA English
DT Article
DE nevus comedonicus; whole-exome sequencing; surgical management; super
   tension-relieving sutures; vacuum sealing drainage
AB Purpose: There are few reports on the comprehensive surgical management of extensive nevus comedonicus, and the genetic mechanism of this rare disease is not yet fully understood. Patients and Methods: We report a case of a 38-year-old woman with extensive nevus comedonicus, refractory to multiple medical treatments. She underwent comb flap reconstruction combined with super tension-relieving sutures and vacuum sealing drainage. In addition, whole-exome sequencing was performed on the lesional tissue samples. Results: Nevus comedonicus was confirmed by physical and histopathological examination. Postoperative recovery was uneventful, and the patient was satisfied with the efficacy. Furthermore, no rare or deleterious mutations were detected in NEK9, FGFR2, ABCA12, or KRT10. Conclusion: Comprehensive surgical intervention is a viable therapeutic option for extensive nevus comedonicus refractory to medical management. Further investigation into the underlying genetic mechanisms of this disease is warranted.
C1 [Cheng, Hui; Li, Xiaojing; Li, Xinyi; Bai, Yun; Zhang, Wei; Zhao, Boao; Yang, Tao; Li, Ping; Yao, Wende] Anhui Med Univ, Affiliated Hosp 1, Dept Plast Surg, Hefei, Anhui, Peoples R China.
C3 Anhui Medical University
RP Yao, WD (通讯作者)，Anhui Med Univ, Affiliated Hosp 1, Dept Plast Surg, Hefei, Anhui, Peoples R China.
EM yaowende2020@126.com
CR Chhabra N, 2014, INDIAN J DERMATOL, V59, DOI 10.4103/0019-5154.135533
   Ganjoo S, 2014, PEDIATR DERMATOL, V31, pE96, DOI 10.1111/pde.12345
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   Kirtak N, 2004, INT J DERMATOL, V43, P434, DOI 10.1111/j.1365-4632.2004.02188.x
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   Levinsohn JL, 2016, AM J HUM GENET, V98, P1030, DOI 10.1016/j.ajhg.2016.03.019
   Mazzella C, 2020, DERMATOL PRACT CONCE, V10, DOI 10.5826/dpc.1001a06
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   Samuelov L, 2015, BRIT J DERMATOL, V173, P293, DOI 10.1111/bjd.13616
NR 10
TC 0
Z9 0
U1 0
U2 0
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
SN 1178-7015
J9 CLIN COSMET INV DERM
JI CLIN. COSMET. INVESTIG. DERMATOL.
PY 2025
VL 18
BP 3533
EP 3536
DI 10.2147/CCID.S574723
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA AD8SQ
UT WOS:001645795600001
PM 41450453
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Petzina, R
   Ugander, M
   Gustafsson, L
   Engblom, H
   Sjögren, J
   Hetzer, R
   Ingemansson, R
   Arheden, H
   Malmsjö, M
AF Petzina, Rainer
   Ugander, Martin
   Gustafsson, Lotta
   Engblom, Henrik
   Sjogren, Johan
   Hetzer, Roland
   Ingemansson, Richard
   Arheden, Hakan
   Malmsjo, Malin
TI Hemodynamic effects of vacuum-assisted closure therapy in cardiac
   surgery:: Assessment using magnetic resonance imaging
SO JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
ID MEDIAN STERNOTOMY INCISION; PERISTERNAL THORACIC WALL; STERNAL
   WOUND-INFECTION; OPEN-HEART PROCEDURES; BLOOD-FLOW; POSTSTERNOTOMY
   MEDIASTINITIS; AGGRESSIVE MANAGEMENT; EARLY INTERVENTION;
   CATHETERIZATION; VALIDATION
AB Objective: The hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery are debated. The aim of the present study was to quantify cardiac output and left ventricular chamber volumes after vacuum-assisted closure using magnetic resonance imaging, which is known to be the most accurate method for quantifying these measures.
   Methods: Six pigs had median sternotomy followed by vacuum-assisted closure treatment in the presence and absence of a paraffin gauze interface dressing. Cardiac output and stroke volume were examined using magnetic resonance imaging flow quantification (breath-hold and real-time). Chamber volumes were assessed using cine magnetic resonance imaging.
   Results: Cardiac output and stroke volume decreased immediately after application of negative pressures of 75, 125, and 175 mm Hg (13% +/- 1% decrease in cardiac output). Interposition of 4 layers of paraffin gauze dressing over the heart during vacuum-assisted closure therapy resulted in a smaller decrease in cardiac output (8% +/- 1%).
   Conclusions: Vacuum-assisted closure therapy results in an immediate decrease in cardiac output, although to a lesser extent than shown previously. Covering the heart with a wound interface dressing lessens the hemodynamic effects of vacuum-assisted closure.
C1 Univ Lund Hosp, Dept Med, S-22185 Lund, Sweden.
   Univ Lund Hosp, Dept Clin Physiol, S-22185 Lund, Sweden.
   Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden.
   German Heart Inst, Berlin, Germany.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital; Lund University; Skane University Hospital; German
   Heart Center Berlin
RP Malmsjö, M (通讯作者)，Lund Univ, BMC A13, SE-22184 Lund, Sweden.
EM malin.malmsjo@med.lu.se
RI Ugander, Martin/AAQ-4447-2021; Sjögren, Johan/AAZ-6448-2021
OI Ugander, Martin/0000-0003-3665-2038; Maljö, Malin/0000-0001-9849-9599;
   Gustafsson, Lotta/0000-0002-9826-9133; Ingemansson,
   Richard/0000-0001-7623-8953; Petzina, Rainer/0000-0002-0688-5482; 
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1997, ANN PLAST SURG, V38, P577
   Arheden H, 1999, RADIOLOGY, V211, P453, DOI 10.1148/radiology.211.2.r99ma43453
   ARHEDEN H, 2006, MRI CT CARDIOVASCULA, P71
   Beerbaum P, 2005, J CARDIOVASC MAGN R, V7, P361, DOI 10.1081/JCMR-200053538
   Bellenger NG, 2000, J CARDIOV MAGN RESON, V2, P271, DOI 10.3109/10976640009148691
   Conquest AM, 2003, J SURG RES, V115, P209, DOI 10.1016/S0022-4804(03)00331-7
   Crabtree Traves D, 2004, Semin Thorac Cardiovasc Surg, V16, P53
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
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   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
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   Jones SM, 2005, PLAST RECONSTR SURG, V116, P1023, DOI 10.1097/01.prs.0000178399.68254.13
   Kuehne T, 2005, HEART, V91, P1064, DOI 10.1136/hrt.2004.038265
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   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Pascoe J R, 1999, Equine Vet J Suppl, P148
   Pennell DJ, 2004, EUR HEART J, V25, P1940, DOI 10.1016/j.ehj.2004.06.040
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   Raudat CW, 1997, AM SURGEON, V63, P238
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   Richardson D, 1997, AM SURGEON, V63, P241
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjogren Johan, 2004, Interact Cardiovasc Thorac Surg, V3, P666, DOI 10.1016/j.icvts.2004.08.003
   *SON CORP, SON PROD INF
   Tang Su-yang, 2004, Zhonghua Zheng Xing Wai Ke Za Zhi, V20, P139
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
NR 28
TC 38
Z9 43
U1 0
U2 6
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0022-5223
EI 1097-685X
J9 J THORAC CARDIOV SUR
JI J. Thorac. Cardiovasc. Surg.
PD MAY
PY 2007
VL 133
IS 5
BP 1154
EP 1162
DI 10.1016/j.jtcvs.2007.01.011
PG 9
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 162BU
UT WOS:000246062300006
PM 17467423
OA Bronze
DA 2026-07-24
ER

PT J
AU Dieu, T
   Leung, M
   Leong, J
   Morrison, W
   Cleland, H
   Archer, B
   Oppy, A
AF Dieu, T
   Leung, M
   Leong, J
   Morrison, W
   Cleland, H
   Archer, B
   Oppy, A
TI Too much vacuum-assisted closure
SO ANZ JOURNAL OF SURGERY
LA English
DT Article
DE early reconstruction; prolonged application; vacuum-assisted closure
ID CLINICAL-EXPERIENCE; NEGATIVE-PRESSURE; WOUND CONTROL
AB There has been an explosion in the use of the vacuum-assisted closure device since 1997. Selectively and judiciously used, it is a valuable tool. However, we are concerned by the expanding list of 'indications' for its use. Prolonged applications, frequently several weeks, at the expense of early surgical reconstruction, might compromise the outcome in selected cases. We report four cases that illustrate this problem and stress the importance of timely surgical reconstruction utilizing the range of reconstructive techniques available as well as vacuum-assisted closure dressing.
C1 Alfred Hosp, Dept Plast & Reconstruct Surg, Melbourne, Vic, Australia.
   St Vincents Hosp, Dept Plast & Reconstruct Surg, Melbourne, Vic, Australia.
C3 Florey Institute of Neuroscience & Mental Health; Howard Florey
   Institute Affiliates; St Vincent's Health; St Vincent's Hospital
   Melbourne; NSW Health; St Vincents Hospital Sydney
RP Dieu, T (通讯作者)，60 Bangalore St, Kensington, Vic 3031, Australia.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Baxandall T, 1997, Elder Care, V9, P22
   Deva A K, 1997, J Wound Care, V6, P311
   Deva AK, 2000, MED J AUSTRALIA, V173, P128, DOI 10.5694/j.1326-5377.2000.tb125564.x
   FLEISCHMANN W, 1995, EUR J ORTHOPAEDICS S, V38, P553
   *KCI INT, 2001, VAC ASS WOUND HEAL B
   Mendez-Eastman S, 1998, Plast Surg Nurs, V18, P27
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Strover AE, 1997, J ROY COLL SURG EDIN, V42, P119
   Wu SH, 2000, EUR J PLAST SURG, V23, P174, DOI 10.1007/s002380050243
NR 11
TC 9
Z9 17
U1 0
U2 0
PU BLACKWELL PUBLISHING ASIA
PI CARLTON
PA 54 UNIVERSITY ST, P O BOX 378, CARLTON, VICTORIA 3053, AUSTRALIA
SN 1445-1433
J9 ANZ J SURG
JI ANZ J. Surg.
PD DEC
PY 2003
VL 73
IS 12
BP 1057
EP 1060
DI 10.1046/j.1445-2197.2003.t01-10-.x
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 747JA
UT WOS:000186800400022
PM 14632906
DA 2026-07-24
ER

PT J
AU Cheung, DC
   Muaddi, H
   de Almeida, JR
   Finelli, A
   Karanicolas, P
AF Cheung, Douglas C.
   Muaddi, Hala
   de Almeida, John R.
   Finelli, Antonio
   Karanicolas, Paul
TI Cost-Effectiveness Analysis of Negative Pressure Wound Therapy to
   Prevent Surgical Site Infection After Elective Colorectal Surgery
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article
DE Cost-effectiveness; Negative pressure wound therapy; Surgical site
   infection
ID INCISIONAL HERNIA; RISK-FACTORS; IMPACT; READMISSIONS; VISITS
AB BACKGROUND: Surgical site infection is common after colorectal surgery and is associated with increased costs. Prophylactic negative pressure wound therapy has previously been shown to reduce surgical site infection compared with conventional dressings. However, negative pressure wound therapy application is met with hesitancy because of its additional cost.
   OBJECTIVE: This study aims to determine whether the application of prophylactic negative pressure wound therapy after elective colorectal surgery is cost-effective.
   DESIGN: A cost-effectiveness analysis comparing prophylactic negative pressure wound therapy versus conventional dressing was completed using a Markov microsimulation model. A publicly funded single health care payer perspective was adopted across a lifetime horizon.
   SETTING: This study was conducted using in-hospital elective colorectal surgery.
   PATIENTS: The base case was an age-, sex-, and comorbidity-standardized patient undergoing open elective colorectal surgery.
   INTERVENTION: Negative pressure wound therapy was applied postoperatively over closed incisions.
   MAIN OUTCOMES: The primary outcomes of interest were the number of surgical site infections, total costs, and quality-adjusted life-years gained. Secondary outcomes included emergency department presentation, hospital readmission, nursing wound care utilization, fascial dehiscence, incisional hernia, and non-surgical site infection-related complications.
   RESULTS: We found that prophylactic negative pressure wound therapy, standardized to 1000 patients, prevented 51 surgical site infections, 3 fascial dehiscences, 10 incisional hernias, 22 emergency department presentations, and 6 hospital readmissions. This resulted in a total cost saving of $17,066 and 92.2 quality-adjusted life-years gained ($17.07 and 0.09 quality-adjusted life-years gained on average per patient). When the patients' risk of surgical site infections was greater than 3.2%, negative pressure wound therapy was a cost-effective strategy at a willingness to pay of $50,000/quality-adjusted life-years.
   LIMITATIONS: We did not model for societal perspective, emergent presentations of incarcerated hernias, or complications with hernia repair. The results of this model are reliant on the published negative pressure wound therapy efficacy and may change when additional data arise.
   CONCLUSION: The use of negative pressure wound therapy is the dominant strategy with improved outcomes and reduced costs compared with conventional dressing in patients undergoing colorectal surgery, particularly in at-risk patients.
C1 [Cheung, Douglas C.; Muaddi, Hala; de Almeida, John R.; Finelli, Antonio; Karanicolas, Paul] Univ Toronto, Dept Surg, Toronto, ON, Canada.
   [de Almeida, John R.] Univ Toronto, Dept Otolaryngol Head & Neck Surg, Toronto, ON, Canada.
   [Finelli, Antonio] Univ Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Div Urol,Dept Surg, Toronto, ON, Canada.
   [de Almeida, John R.; Karanicolas, Paul] Sunnybrook Hlth Sci Ctr, Div Gen Surg, Toronto, ON, Canada.
   [Karanicolas, Paul] Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada.
C3 University of Toronto; University of Toronto; University of Toronto;
   University Health Network Toronto; Princess Margaret Cancer Centre;
   University of Toronto; Sunnybrook Health Science Center; Sunnybrook
   Research Institute; University of Toronto
RP Karanicolas, P (通讯作者)，Sunnybrook Hlth Sci Ctr, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada.
EM paul.karanicolas@sunnybrook.ca
RI Muaddi, Hala/AAE-1264-2021
CR Amri R, 2017, JAMA SURG, V152, P686, DOI 10.1001/jamasurg.2017.0505
   [Anonymous], 2017, CADTH Methods and Guidelines. Guidelines for the economic evaluation of health technologies: Canada, V4th
   Arnold M, 2017, GUT, V66, P683, DOI 10.1136/gutjnl-2015-310912
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   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Chomsky-Higgins K, 2018, SURGERY, V163, P197, DOI 10.1016/j.surg.2017.07.030
   Chopra K, 2016, PLAST RECONSTR SURG, V137, P1284, DOI 10.1097/PRS.0000000000002024
   Cone MM, 2011, ARCH SURG-CHICAGO, V146, P594, DOI 10.1001/archsurg.2011.79
   Hansen DG, 2013, DIS COLON RECTUM, V56, P1053, DOI 10.1097/DCR.0b013e318293eabc
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   Keenan JE, 2014, JAMA SURG, V149, P1045, DOI 10.1001/jamasurg.2014.346
   Kim JJ, 2017, PRS-GLOB OPEN, V5, DOI 10.1097/GOX.0000000000001211
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   Ontario Nurses Association, 2020, ONT NURS ASS COLL AG
   Sahebally SM, 2018, JAMA SURG, V153, DOI 10.1001/jamasurg.2018.3467
   Schlussel AT, 2016, DIS COLON RECTUM, V59, P843, DOI 10.1097/DCR.0000000000000642
   Segev DL, 2020, JAMA SURG, V155, P436, DOI 10.1001/jamasurg.2019.5377
   Shiroky J, 2020, SURGERY, V167, P1001, DOI 10.1016/j.surg.2020.01.018
   Soderback H, 2018, INT J COLORECTAL DIS, V33, P1411, DOI 10.1007/s00384-018-3124-5
   Tuffaha HW, 2015, J SURG RES, V195, P612, DOI 10.1016/j.jss.2015.02.008
   van Ramshorst GH, 2010, WORLD J SURG, V34, P20, DOI 10.1007/s00268-009-0277-y
   Vanni T, 2011, PHARMACOECONOMICS, V29, P35, DOI 10.2165/11584600-000000000-00000
   Walming S, 2017, BMC SURG, V17, DOI 10.1186/s12893-017-0207-0
   Webster J, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub4
   Wilson MZ, 2016, AM J SURG, V212, P844, DOI 10.1016/j.amjsurg.2015.12.025
   Wood T, 2018, J GASTROINTEST SURG, V22, P259, DOI 10.1007/s11605-017-3555-2
   Young H, 2012, J AM COLL SURGEONS, V214, P852, DOI 10.1016/j.jamcollsurg.2012.01.041
NR 32
TC 2
Z9 4
U1 2
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD MAY
PY 2022
VL 65
IS 5
BP 767
EP 776
DI 10.1097/DCR.0000000000002154
PG 10
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 0I5JN
UT WOS:000779456900037
PM 34840300
DA 2026-07-24
ER

PT J
AU Okkabaz, N
   Esen, E
   Schwartzberg, DM
   Remzi, FH
   Kirat, HT
AF Okkabaz, Nuri
   Esen, Eren
   Schwartzberg, David M.
   Remzi, Feza H.
   Kirat, Hasan T.
TI Hand-Crafted Endoluminal Vacuum-Assisted Drainage for Anastomotic Leak
   After IPAA
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article; Proceedings Paper
CT Meeting of the American-Society-of-Colon-and-Rectal-Surgeons
CY MAY 03-07, 2019
CL San Diego, CA
SP Amer Soc Colon & Rectal Surg
DE Anastomotic leak; Endoluminal vacuum-assisted closure; Hand crafted;
   Ileal pouch-anal anastomosis; Vacuum-assisted closure
ID POUCH-ANAL ANASTOMOSIS; PROCTOCOLECTOMY; THERAPY
AB INTRODUCTION: The vacuum-assisted drainage has many applications in managing complex wound healing. It quickens the recovery period by its hyperemic effect on the exposed zone, decreasing bacterial colonization, preventing tissue edema, and promoting granulation of the wound. However, its use in anastomotic leak after IPAA is scarcely studied, especially because a proprietary endoluminal vacuum-assisted closure system was removed from the US market. TECHNIQUE: We applied a hand-crafted endoluminal vacuum-assisted closure system using the existing standard wound vacuum-assisted closure supplies to 2 patients who developed an anastomotic leak with a presacral abscess after completion proctectomy with J-pouch construction. RESULTS: We changed the endoluminal vacuum-assisted closure drain every 2 to 3 days, and both patients had substantial improvements in their abscess cavity after the seventh and ninth applications. CONCLUSIONS: Anastomotic leak at the IPAA traditionally takes up to a year to heal, which causes a significant toll on the psychosocial life of the patient and delayed stoma closure. Therefore, we believe that facilitating the healing process by using our hand-crafted endoluminal vacuum-assisted closure drain might provide a great value to patients' quality of life.
C1 [Okkabaz, Nuri] Bagcilar Training & Res Hosp, Dept Surg, Istanbul, Turkey.
   [Esen, Eren; Schwartzberg, David M.; Remzi, Feza H.; Kirat, Hasan T.] NYU, Dept Surg, Langone Med Ctr, New York, NY 10016 USA.
C3 Istanbul Bagcilar Training & Research Hospital; NYU Langone Medical
   Center; New York University
RP Kirat, HT (通讯作者)，NYU Langone Med Ctr, IBD Ctr, 240 East 38th St,23rd Floor, New York, NY 10016 USA.
EM tarik.kirat@nyulangone.org
RI Remzi, Feza/AAE-6584-2022; Okkabaz, Nuri/U-4054-2019; Esen,
   Eren/AAF-3624-2021
CR Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Fazio VW, 2013, ANN SURG, V257, P679, DOI 10.1097/SLA.0b013e31827d99a2
   Gardenbroek TJ, 2015, COLORECTAL DIS, V17, P426, DOI 10.1111/codi.12867
   Kiely JM, 2012, DIS COLON RECTUM, V55, P387, DOI 10.1097/DCR.0b013e318246418e
   PARKS AG, 1978, BMJ-BRIT MED J, V2, P85, DOI 10.1136/bmj.2.6130.85
   Pournaras DJ, 2018, WORLD J SURG, V42, P2507, DOI 10.1007/s00268-018-4463-7
   Remzi FH, 2017, COLORECTAL DIS, V19, P1003, DOI 10.1111/codi.13699
   Rottoli M, 2018, TECH COLOPROCTOL, V22, P223, DOI 10.1007/s10151-018-1762-9
   Weidenhagen R, 2008, Rozhl Chir, V87, P397
NR 9
TC 8
Z9 8
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD OCT
PY 2019
VL 62
IS 10
BP 1259
EP 1262
DI 10.1097/DCR.0000000000001453
PG 4
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Gastroenterology & Hepatology; Surgery
GA KF6CY
UT WOS:000509329000019
PM 31490837
DA 2026-07-24
ER

PT J
AU Barabino, G
   Filippello, A
   Brek, A
   Cuilleron, M
   Dumas, O
   Rinaldi, L
   Porcheron, J
AF Barabino, Gabriele
   Filippello, Alexandre
   Brek, Amine
   Cuilleron, Muriel
   Dumas, Olivier
   Rinaldi, Leslie
   Porcheron, Jack
TI Management of an Esojejunal Intrathoracic Leak Using an Endoscopic
   Vacuum-assisted Closure Technique
SO SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES
LA English
DT Article
DE endoscopic vacuum-assisted closure; esojejunal anastomosis; leak;
   surgery
ID ANASTOMOTIC LEAK; STENT
AB Management of intrathoracic anastomotic leaks remains an important clinical challenge. We describe a case about a patient with intrathoracic esophageal anastomotic leaks after oesogastrectomy. Ndoscopic Vacuum-assisted closure technique today is an effective alternative in the treatment of anastomotic leaks after upper gastrointestinal tract surgery.
C1 [Barabino, Gabriele; Filippello, Alexandre; Brek, Amine; Porcheron, Jack] Univ Hosp St Etienne, Dept Digest & Oncol Surg, St Priest En Jarez, France.
   [Cuilleron, Muriel] Univ Hosp St Etienne, Dept Radiol, St Priest En Jarez, France.
   [Dumas, Olivier; Rinaldi, Leslie] Univ Hosp St Etienne, Gastroenterol Unit, St Priest En Jarez, France.
C3 CHU de St Etienne; CHU de St Etienne; CHU de St Etienne
RP Barabino, G (通讯作者)，Nord Hosp, Univ Hosp St Etienne, Dept Digest & Oncol Surg, Ave Albert Raymond, F-42270 St Priest En Jarez, France.
EM gabriele.barabino@chu-st-etienne.fr
CR Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Kassis ES, 2013, ANN THORAC SURG, V96, P1919, DOI 10.1016/j.athoracsur.2013.07.119
   Leers JM, 2009, SURG ENDOSC, V23, P2258, DOI 10.1007/s00464-008-0302-5
   Markar S, 2015, ANN SURG ONCOL, V22, P2615, DOI 10.1245/s10434-014-4310-5
   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
NR 5
TC 1
Z9 3
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1530-4515
EI 1534-4908
J9 SURG LAPARO ENDO PER
JI Surg. Laparosc. Endosc. Pct. Tech.
PD JUN
PY 2017
VL 27
IS 3
BP e26
EP e27
DI 10.1097/SLE.0000000000000393
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EX2QU
UT WOS:000403072300002
PM 28383315
DA 2026-07-24
ER

PT J
AU Zhang, JC
   Kang, MJ
   Zhu, L
   Su, S
AF Zhang, Jin-chang
   Kang, Mao-ji
   Zhu, Lin
   Su, Song
TI Negative-pressure wound therapy to decrease surgical-site infection in
   patients undergoing pancreaticoduodenectomy: A systematic review and
   meta-analysis
SO ASIAN JOURNAL OF SURGERY
LA English
DT Letter
DE Negative pressure wound therapy; Pancreaticoduodenectomy; Surgical site
   infection; Meta-analysis; Systematic review
ID RISK
C1 [Zhang, Jin-chang; Kang, Mao-ji; Zhu, Lin; Su, Song] Southwest Med Univ, Dept Gen Surg Hepatobiliary Surg, Affiliated Hosp, Taiping St 25, Luzhou 646000, Sichuan, Peoples R China.
C3 Southwest Medical University
RP Su, S (通讯作者)，Southwest Med Univ, Dept Gen Surg Hepatobiliary Surg, Affiliated Hosp, Taiping St 25, Luzhou 646000, Sichuan, Peoples R China.
EM 437842121@qq.com; 1098490062@qq.com; 393828331@qq.com;
   13882778554@163.com
OI zhang, Jin-chang/0000-0002-1027-1715
FU Study on Artificial Intelligence Assisted Diagnosis technology of MRI
   Images of Periampullary Carcinoma (Sichuan Provincial Department of
   Science and Technology);  [20zdy1229]
FX This study was supported by Study on Artificial Intelligence Assisted
   Diagnosis technology of MRI Images of Periampullary Carcinoma (Sichuan
   Provincial Department of Science and Technology: 20zdy1229) .
CR Anderson DJ, 2014, INFECT CONT HOSP EP, V35, P605, DOI 10.1086/676022
   Andrianello S, 2021, SURGERY, V169, P1069, DOI 10.1016/j.surg.2020.10.029
   Kneuertz PJ, 2012, J GASTROINTEST SURG, V16, P1727, DOI 10.1007/s11605-012-1938-y
   Meyer J, 2021, CLIN INFECT DIS, V73, pE3804, DOI 10.1093/cid/ciaa1203
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
NR 5
TC 3
Z9 3
U1 0
U2 5
PU ELSEVIER SINGAPORE PTE LTD
PI SINGAPORE
PA 3 KILLINEY ROAD 08-01, WINSLAND HOUSE 1, SINGAPORE, 239519, SINGAPORE
SN 1015-9584
EI 0219-3108
J9 ASIAN J SURG
JI Asian J. Surg.
PD DEC
PY 2022
VL 45
IS 12
BP 2742
EP 2744
DI 10.1016/j.asjsur.2022.06.020
EA NOV 2022
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 8H4OJ
UT WOS:000921013200024
PM 35810114
OA gold
DA 2026-07-24
ER

PT J
AU Huang, YL
   Ju, F
   Lai, SC
   Chen, ZC
   Chen, XY
   Zhou, LH
   Fu, MX
AF Huang, Y. L.
   Ju, F.
   Lai, S. C.
   Chen, Z. C.
   Chen, X. Y.
   Zhou, L. H.
   Fu, M. X.
TI EFFECTS OF NEGATIVE PRESSURE WOUND THERAPY ASSOCIATED WITH LOCAL INSULIN
   INJECTION ON TGF-β1 EXPRESSION IN DIABETIC FOOT WOUNDS
SO JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
LA English
DT Article
DE diabetic foot; negative-pressure wound therapy; insulin; transforming
   growth factor beta 1
ID RESISTANCE
C1 [Huang, Y. L.; Ju, F.; Lai, S. C.; Chen, Z. C.; Chen, X. Y.; Zhou, L. H.; Fu, M. X.] Hainan Med Coll, Affiliated Hosp 2, Dept Endocrinol, Haikou 70311, Hainan, Peoples R China.
C3 Hainan Medical University
RP Fu, MX (通讯作者)，Hainan Med Coll, Affiliated Hosp 2, Dept Endocrinol, Haikou 70311, Hainan, Peoples R China.
EM fumaoxiong_haikmd@163.com
RI Zhou, Linghui/ABB-1729-2021
CR Branski LK, 2009, BURNS, V35, P171, DOI 10.1016/j.burns.2008.03.009
   Calina D, 2017, MOL MED REP, V15, P681, DOI 10.3892/mmr.2016.6034
   Giangreco A, 2010, J INVEST DERMATOL, V130, P604, DOI 10.1038/jid.2009.297
   Lima MHM, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0036974
   Sepúlveda G, 2009, CIR ESPAN, V86, P171, DOI 10.1016/j.ciresp.2009.03.020
   Wang J, 2015, MINERVA CHIR, V70, P17
   Wang L, 2017, SCI REP-UK, V7, DOI 10.1038/s41598-017-01116-5
   Wentworth JM, 2010, DIABETES, V59, P1648, DOI 10.2337/db09-0287
   Zhang PZ, 2017, ANN MED, V49, P106, DOI 10.1080/07853890.2016.1231932
NR 9
TC 0
Z9 0
U1 0
U2 14
PU BIOLIFE SAS
PI SILVA MARINA (TE)
PA VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY
SN 0393-974X
EI 1724-6083
J9 J BIOL REG HOMEOS AG
JI J. Biol. Regul. Homeost. Agents
PD MAR-APR
PY 2020
VL 34
IS 2
BP 559
EP 564
PG 6
WC Endocrinology & Metabolism; Immunology; Medicine, Research &
   Experimental; Physiology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism; Immunology; Research & Experimental
   Medicine; Physiology
GA LQ8FL
UT WOS:000535233600027
PM 32506883
DA 2026-07-24
ER

PT J
AU Omran, N
   Habal, P
   Mandak, J
   Chek, JL
AF Omran, Nedal
   Habal, Petr
   Mandak, Jiri
   Chek, James L.
TI Broncho-Pleural Fistula Following Vacuum-Assisted Closure Therapy
SO JOURNAL OF CARDIAC SURGERY
LA English
DT Article
AB Wereport a case of bronchopleural- cutaneous fistula following long-term vacuum-assisted closure therapy to manage a sternal dehiscence after coronary artery bypass surgery.
C1 Charles Univ Prague, Fac Med, Dept Cardiac Surg, Hradec Kralove, Czech Republic.
   Charles Univ Prague, Fac Hosp Hradec Kralove, Dept Cardiac Surg, Hradec Kralove, Czech Republic.
C3 University Hospital Hradec Kralove; Charles University Prague;
   University Hospital Hradec Kralove; Charles University Prague
RP Omran, N (通讯作者)，Charles Univ Hosp, Dept Cardiac Surg, Sokolska 581, Hradec Kralove 50005, Czech Republic.
EM nidal81@gmail.com
RI /AAK-7375-2021; Chek, James Lago/E-4971-2018; Habal, Petr/O-3068-2017;
   Manďák, Jiří/H-5767-2016
OI Chek, James Lago/0000-0001-9957-5071; Habal, Petr/0000-0002-7338-0185;
   Manďák, Jiří/0000-0003-3673-0534
FU research programme PRVOUK [P-37/04]
FX The work was supported by the research programme PRVOUK P-37/04
CR Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Kiessling AH, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-16
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Petzina R, 2006, EUR J CARDIO-THORAC, V30, P85, DOI 10.1016/j.ejcts.2006.04.009
   Sartipy U, 2006, ANN THORAC SURG, V82, P1110, DOI 10.1016/j.athoracsur.2006.01.060
   TAVILLA G, 1991, ANN THORAC SURG, V52, P1179, DOI 10.1016/0003-4975(91)91310-R
NR 7
TC 5
Z9 6
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0886-0440
EI 1540-8191
J9 J CARDIAC SURG
JI J. Card. Surg.
PD JUL
PY 2013
VL 28
IS 4
BP 397
EP 398
DI 10.1111/jocs.12126
PG 2
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 188BR
UT WOS:000322167100016
PM 23711339
DA 2026-07-24
ER

PT J
AU Leijnen, M
   Steenvoorde, P
   van Doorn, LP
   da Costa, SA
   Schuttevaer, HM
   van Leeuwen, GAM
   Oskam, J
AF Leijnen, Michiel
   Steenvoorde, Pascal
   van Doorn, Louk P.
   da Costa, S. A.
   Schuttevaer, Herman M.
   van Leeuwen, Gijs A. M.
   Oskam, Jaques
TI A non-healing sinus of the lower leg 5 years after vacuum-assisted
   closure therapy due to a gossypiboma
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID SURGERY
AB Due to the development of vacuum-assisted closure therapy (V.A C.(R) Therapy (TM), KCl, San Antonio, Tex), chronic wound care has taken a step forward. Vacuum-assisted closure has proven to be effective in the treatment of chronic and acute wounds. Although most complications are rare, localized superficial skin irritation is the most common complication reported in the literature. Further complications involve pain, infection, bleeding, and fluid depletion. The authors present a case of a chronic fistula 5 years after vacuum-assisted closure therapy as a result of a piece of foam dressing that was left inside a wound. The retainment of vacuum-assisted closure dressings is a serious complication that can easily be prevented when proper precautions are taken during dressing changes.
C1 Rijnland Hosp, Dept Surg, Leiderdorp, Netherlands.
   Rijnland Wound Ctr, Leiderdorp, Netherlands.
   Rijnland Hosp, Dept Radiol, Leiderdorp, Netherlands.
   Rijnland Hosp, Dept Pathol, Leiderdorp, Netherlands.
C3 Rijnland Hospital; Rijnland Hospital; Rijnland Hospital
RP Leijnen, M (通讯作者)，Rijnland Hosp Leiderdorp, Simon Smitweg 1, Leiderdorp, Netherlands.
EM m.leijnen@rijnland.nl
CR ABDULKARIM FW, 1992, SKELETAL RADIOL, V21, P466
   Carson Stanley N, 2004, Ostomy Wound Manage, V50, P52
   Ford CN, 2002, ANN PLAS SURG, V49, P55, DOI 10.1097/00000637-200207000-00009
   Fox A, 2004, J Wound Care, V13, P344
   Gawande AA, 2003, NEW ENGL J MED, V348, P229, DOI 10.1056/NEJMsa021721
   Gwan-Nulla DN, 2001, ANN PLAS SURG, V47, P552, DOI 10.1097/00000637-200111000-00014
   Karl T, 2004, ZBL CHIR, V129, pS74, DOI 10.1055/s-2004-822609
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   LEIJNEN M, IN PRESS J WOUND CAR
   MORKYWAS MJ, 1997, ANN PLAST SURG, V38, P553
   Rajagopal A, 2002, DIS COLON RECTUM, V45, P119, DOI 10.1007/s10350-004-6124-1
   Rozeboom A L, 2006, J Wound Care, V15, P117
   Steenvoorde P, 2004, PLAST RECONSTR SURG, V113, P2220, DOI 10.1097/01.PRS.0000123603.32963.11
   NEGATIVE PRESSUE WOU
NR 14
TC 6
Z9 7
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD AUG
PY 2007
VL 19
IS 8
BP 227
EP 230
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 222AD
UT WOS:000250267600005
PM 26110367
DA 2026-07-24
ER

PT J
AU Stone, P
   Prigozen, J
   Hofeldt, M
   Hass, S
   DeLuca, J
   Flaherty, S
AF Stone, P
   Prigozen, J
   Hofeldt, M
   Hass, S
   DeLuca, J
   Flaherty, S
TI Bolster versus negative pressure wound therapy for securing
   split-thickness skin grafts in trauma patients
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE
AB Purpose: The purpose of this retrospective chart review was to compare the effectiveness of negative pressure wound therapy (NPWT) (Vacuum-Assisted Therapy(R), V.A.C.(R), Kinetic Concepts, Inc., San Antonio, Texas) to traditional cotton bolster dressings in split-thickness skin graft (STSG) survival in trauma patients. Methods: The authors conducted a retrospective chart review of 40. patients admitted to a level I trauma center over a two-year period and treated with split-thickness skin grafting, with in-hospital graft survival as the main endpoint. Results: Forty patients underwent STSG placement over 46 wounds. Indications included soft tissue loss (graft n = 34) and fasciotomy site (n = 12). The grafts were secured using either NPWT (n = 21) or a traditional cotton bolster (n = 25). Zero grafts failed in the NPWT group, while one graft failure occurred in the bolster group on a sizeable soft tissue loss injury to the torso/extremity (300cm(2) graft). There were no significant differences in graft failure, mean graft size, total length of patient hospital stay; or length of time the dressings were left in place between the NPWT and bolster groups. Treatment costs were considerably larger in the NPWT group. The average cost per patient in the NPWT and cotton bolster groups were approximately $1,000 and $18.50, respectively. Conclusion: The in-hospital results achieved with NPWT compare well to the traditional cotton bolsters, with NPWT being a viable option for securing STSG and ensuring graft survival. However, the routine use of NPWT may not be cost effective. A prospective, randomized trial examining grafts with higher associated failure rates using these two modalities would help answer questions about NPWT's use in this patient population.
C1 W Virginia Univ, Sch Med, Charleston, WV USA.
C3 West Virginia University
RP Flaherty, S (通讯作者)，Charleston Area Med Ctr, Hlth Educ & Res Inst, 3211 MacCorkle Ave SE, Charleston, WV 25304 USA.
EM sarah.flaherty@camc.org
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Levit K, 2004, HEALTH AFFAIR, V23, P147, DOI 10.1377/hlthaff.23.1.147
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Rudolph R., 1990, PLASTIC SURG, VI, P221
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
NR 6
TC 19
Z9 24
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUL
PY 2004
VL 16
IS 7
BP 219
EP 223
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 840LV
UT WOS:000222861000001
DA 2026-07-24
ER

PT J
AU Cain, CJ
   Margolis, M
   Lazar, JF
   Henderson, H
   Hamm, M
   Malouf, S
   Khaitan, PG
AF Cain, Caitlin J.
   Margolis, Marc
   Lazar, John F.
   Henderson, Hayley
   Hamm, Margaret
   Malouf, Stefanie
   Khaitan, Puja Gaur
TI Short and long-term outcomes of surgical intervention for empyema in the
   post-fibrinolytic era
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
DE Empyema; Open window Thoracostomy; Bronchopleural fistula
ID TISSUE-PLASMINOGEN ACTIVATOR; VACUUM-ASSISTED CLOSURE; MANAGEMENT
AB Background Open window thoracostomy (OWT) is indicated for patients with bronchopleural fistula (BPF) or trapped lung in the setting of empyema refractory to non-surgical interventions. We investigated the role of OWT in the era of minimally invasive surgeries, endobronchial valves and fibrinolytic therapy. Methods A retrospective chart review of all patients who underwent OWT at a single institution from 2010 to 2020 was performed. Indications for the procedure as well as operative details and morbidity and mortality were evaluated to determine patient outcomes for OWT. Results Eighteen patients were identified for the study. The most common indication for OWT was post-resectional BPF (n = 9). Prior to OWT, n = 11 patients failed other surgical or minimally invasive interventions. Patient comorbidities were quantified with the Charlson Comorbidity index (n = 11 score >= 5, 10-year survival <= 21%). Three (16.7%) patients died < 30 days post-operatively and 12 (66%) patients were deceased by the study's end (overall survival 24.0 +/- 32.2 months). Mean number of ribs resected were 2.5 +/- 1.2 (range 1-6) with one patient having 6 ribs removed. Patients were managed with negative pressure wound therapy (n = 9) or Kerlix packing (n = 9). Eleven patients (61.6%) underwent delayed closure (mean time from index surgery to closure 4.8 +/- 6.7 months). Conclusions Our study illustrates the significant comorbidities of patients undergoing OWT, the poor outcomes therein, and pitfalls associated with this procedure. We show that negative pressure wound therapy can be utilized as potential way to obliterate the pleural space and manage an open chest in the absence of an airleak; however, OWT procedures continue to be extremely morbid.
C1 [Cain, Caitlin J.; Margolis, Marc; Lazar, John F.; Khaitan, Puja Gaur] Georgetown Univ, Sch Med, Medstar Washington Hosp Ctr, Dept Gen Surg, 110 Irving St,NW G253, Washington, DC 20010 USA.
   [Margolis, Marc; Lazar, John F.; Henderson, Hayley; Hamm, Margaret; Malouf, Stefanie; Khaitan, Puja Gaur] Georgetown Univ, Sch Med, Medstar Washington Hosp Ctr, Div Thorac Surg, 110 Irving St,NW G253, Washington, DC 20010 USA.
C3 MedStar Washington Hospital Center; Georgetown University; Georgetown
   University; MedStar Washington Hospital Center
RP Khaitan, PG (通讯作者)，Georgetown Univ, Sch Med, Medstar Washington Hosp Ctr, Dept Gen Surg, 110 Irving St,NW G253, Washington, DC 20010 USA.; Khaitan, PG (通讯作者)，Georgetown Univ, Sch Med, Medstar Washington Hosp Ctr, Div Thorac Surg, 110 Irving St,NW G253, Washington, DC 20010 USA.
EM Puja.G.Khaitan@medstar.net
RI Khaitan, Puja/AAQ-6413-2020
OI Khaitan, Puja/0000-0001-8654-062X; Cain-Trivette, Caitlin
   J/0000-0003-4141-275X
CR Chambers A, 2010, INTERACT CARDIOV TH, V11, P171, DOI 10.1510/icvts.2010.240408
   CLAGETT OT, 1963, J THORAC CARDIOV SUR, V45, P141, DOI 10.1016/S0022-5223(19)32877-6
   Eloesser L, 1969, Ann Thorac Surg, V8, P355
   Eloesser L, 1935, CHEST, V1, P23, DOI [10.1378/chest.1.8.8, DOI 10.1378/CHEST.1.8.8]
   Fiorelli A, 2018, J THORAC DIS, V10, P6158, DOI 10.21037/jtd.2018.10.61
   Haghshenasskashani A, 2011, INTERACT CARDIOV TH, V13, P168, DOI 10.1510/icvts.2011.267286
   Heimes J, 2017, J THORAC DIS, V9, P1310, DOI 10.21037/jtd.2017.04.56
   Ho CH, 2017, MEDICINE, V96, DOI 10.1097/MD.0000000000008040
   Hofmann HS, 2012, ANN THORAC SURG, V93, P1741, DOI 10.1016/j.athoracsur.2011.12.039
   Liang S, 2020, Adult Chest Surgery, V3, P995
   Maskell NA, 2005, NEW ENGL J MED, P10
   Nayak R, 2020, CHEST, V157, P1114, DOI 10.1016/j.chest.2019.11.040
   Nishii K, 2021, GEN THORAC CARDIOVAS, V69, P843, DOI 10.1007/s11748-020-01554-5
   Oyetunji TA, 2020, J PEDIATR SURG, V55, P2352, DOI 10.1016/j.jpedsurg.2019.12.023
   Palmen M, 2009, ANN THORAC SURG, V88, P1131, DOI 10.1016/j.athoracsur.2009.06.030
   Piccolo F, 2015, J THORAC DIS, V7, P999, DOI 10.3978/j.issn.2072-1439.2015.01.30
   Rahman NM, 2011, NEW ENGL J MED, V365, P518, DOI 10.1056/NEJMoa1012740
   Reyes KG, 2010, THORAC CARDIOV SURG, V58, P220, DOI 10.1055/s-0029-1240972
   Symbas P N, 1971, Ann Thorac Surg, V12, P69
   Thourani VH, 2003, ANN THORAC SURG, V76, P401, DOI 10.1016/S0003-4975(03)00470-3
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   Wait Michael A, 2007, J Minim Access Surg, V3, P141, DOI 10.4103/0972-9941.38908
NR 22
TC 8
Z9 9
U1 0
U2 0
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD JUL 2
PY 2021
VL 16
IS 1
AR 187
DI 10.1186/s13019-021-01566-z
PG 7
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA TD2ZT
UT WOS:000669201900001
PM 34215289
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Di Re, AM
   Wright, D
   Toh, JWT
   El-Khoury, T
   Pathma-Nathan, N
   Gosselink, MP
   Khanijaun, S
   Raman, S
   Ctercteko, G
AF Di Re, A. M.
   Wright, D.
   Toh, J. W. T.
   El-Khoury, T.
   Pathma-Nathan, N.
   Gosselink, M. P.
   Khanijaun, S.
   Raman, S.
   Ctercteko, G.
TI Surgical wound infection prevention using topical negative pressure
   therapy on closed abdominal incisions-the ?SWIPE IT? randomized clinical
   trial
SO JOURNAL OF HOSPITAL INFECTION
LA English
DT Article
DE Colorectal surgery; Surgical site infections; Trauma surgery; Emergency
   surgery; Negative pressure wound therapy
ID VACUUM-ASSISTED CLOSURE; SITE INFECTION; COLORECTAL SURGERY;
   OBESE-PATIENTS
AB Background: Surgical site infections (SSIs) are the most common cause of healthcare associated infections in surgical patients. It is unclear whether incisional negative pressure wound therapy (NPWT) can reduce the risk of SSIs in patients after open abdominal surgery.
   Methods: A prospective, non-blinded multi-centre randomized controlled trial (RCT) was performed to evaluate the incidence of SSI post-laparotomy using incisional NPWT compared with a standard dressing. The primary outcome was the rate of superficial SSI.
   Results: A total of 124 patients (61 patients in the NPWT arm and 63 patients in the control arm) were included. One hundred and nine (87.9%) patients underwent colorectal surgery; 61 patients (49.2%) had emergency surgery. There were more superficial SSIs in the control group than in the NPWT group, although not statistically significant (20.6% vs 9.8%, P=0.1). Upon multiple logistic regression analysis, control dressings were associated with increased risk of superficial SSI although again, not statistically significant (odds ratio (OR) 2.41, 95% confidence interval (CI) 0.81-7.17, P=0.11). There was no superficial non-SSI related wound dehiscence in the NPWT group compared with 9.5% in the control group (P=0.03). There was no difference in postoperative complications (P=0.15), nor in other wound complications (P=0.79).
   Conclusion: NPWT was not associated with decreased superficial SSI in this RCT. However, there was a statistically significant reduction in superficial wound dehiscence with NWPT dressings. The results of this study should be included in meta-analyses for better evaluation of NPWT on closed abdominal incisions.
C1 [Di Re, A. M.; Wright, D.; Toh, J. W. T.; El-Khoury, T.; Pathma-Nathan, N.; Gosselink, M. P.; Khanijaun, S.; Raman, S.; Ctercteko, G.] Westmead Hosp, Dept Colorectal Surg, Cnr Hawkesbury Rd & Darcy Rd, Westmead, NSW 2145, Australia.
   [Di Re, A. M.] Univ Sydney, Sch Phys, Sydney, NSW, Australia.
   [Wright, D.; Ctercteko, G.] Blacktown Mt Druitt Hosp, Dept Surg, Mt Druitt, NSW, Australia.
   [Toh, J. W. T.; Ctercteko, G.] Univ Sydney, Sch Med, Sydney, NSW, Australia.
   [El-Khoury, T.] Notre Dame Univ, Sch Med, Sydney, NSW, Australia.
   [Gosselink, M. P.] Dr Horacio E Oduber Hosp, Oranjestad, Aruba.
   [Raman, S.] Univ Hosp Birmingham NHS Fdn Trust, Heartlands Hosp, Birmingham, W Midlands, England.
C3 NSW Health; Westmead Hospital; University of Sydney; University of
   Sydney; NSW Health; Blacktown & Mount Druitt Hospital; University of
   Sydney; The University of Notre Dame Australia; University of
   Birmingham; Heart of England NHS Foundation Trust; Heartlands Hospital
RP Di Re, AM (通讯作者)，Westmead Hosp, Dept Colorectal Surg, Cnr Hawkesbury Rd & Darcy Rd, Westmead, NSW 2145, Australia.
EM Angelina.dire@gmail.com
RI ; Gosselink, Martijn/D-1564-2009
OI Khanijaun, Sukhwant/0000-0002-6256-2522; El-Khoury,
   Toufic/0009-0007-2133-6063; Gosselink, Martijn/0000-0002-6396-3977
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NR 31
TC 15
Z9 19
U1 1
U2 8
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 0195-6701
EI 1532-2939
J9 J HOSP INFECT
JI J. Hosp. Infect.
PD APR
PY 2021
VL 110
BP 76
EP 83
DI 10.1016/j.jhin.2021.01.013
EA FEB 2021
PG 8
WC Public, Environmental & Occupational Health; Infectious Diseases
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Public, Environmental & Occupational Health; Infectious Diseases
GA RB8FP
UT WOS:000632342500011
PM 33516795
DA 2026-07-24
ER

PT J
AU Dwivedi, MK
   Srivastava, RN
   Bhagat, AK
   Agarwal, R
   Baghel, K
   Jain, A
   Raj, S
AF Dwivedi, M. K.
   Srivastava, R. N.
   Bhagat, A. K.
   Agarwal, R.
   Baghel, K.
   Jain, A.
   Raj, S.
TI Pressure ulcer management in paraplegic patients with a novel negative
   pressure device: a randomised controlled trial
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE pressure ulcer; negative pressure wound therapy; negative pressure
   device
ID VACUUM-ASSISTED CLOSURE; WOUND THERAPY; PREVENTION; COST
AB Objective: A randomised controlled trial to compare negative pressure wound therapy (NPWT) using our innovative negative pressure device (NPD) and the standard pressure ulcer (PU) wound dressing of in traumatic paraplegia patients.
   Method: This study was conducted in the Department of Orthopaedic Surgery at King George's Medical University, Lucknow, India. Traumatic paraplegia patients with sacral pressure ulcers of stage 3 and 4 were randomised into two groups, receiving either standard wound dressings or NPWT with NPD. The outcomes monitored were length, width (surface area), depth of PU, exudates, discharge, tissue type (necrotic, slough and red granulating tissue), and cost-effectiveness during 0 to 9 weeks follow-up.
   Results: Length and width were significantly (p<0.01) decreased in NPWT group as compared with standard care group at week 9. At weeks 1, 2 and 3, depth was significantly (p<0.05) higher in NPWT group, whereas at week 9 a significant reduction (p=0.01) was observed. Exudates were significantly (p=0.001) lower in NPWT group at weeks 4 and 9. Conversion of slough into red granulation tissue was significantly higher in NPWT group (p=0.001). Discharge became significantly (p=0.001) lower in NPWT at week 2 and no discharge was observed after week 6. In all parameters, decrease was larger in NPWT group compared with standard care, which was significant for exudates type (p=0.03) and tissue type (p=0.004).
   Conclusion: Our NPD is better than standard wound care procedures and cost-effective for management of PU.
C1 [Dwivedi, M. K.; Srivastava, R. N.; Baghel, K.] King Georges Med Univ, Dept Orthopaed Surg, Lucknow, Uttar Pradesh, India.
   [Bhagat, A. K.] King Georges Med Univ, Dept Surg Gastroenterol, Lucknow, Uttar Pradesh, India.
   [Agarwal, R.] Sanjai Gandhi Post Grad Inst Med Sci SGPGIMS, Dept Plast Surg, Lucknow, Uttar Pradesh, India.
   [Jain, A.] King Georges Med Univ, Dept Microbiol, Lucknow, Uttar Pradesh, India.
   [Raj, S.] MS Ramiyah Med Coll, Bangalore, Karnataka, India.
C3 King George's Medical University; King George's Medical University;
   Sanjay Gandhi Postgraduate Institute of Medical Sciences; King George's
   Medical University
RP Srivastava, RN (通讯作者)，King Georges Med Univ, Dept Orthopaed Surg, Lucknow, Uttar Pradesh, India.
EM drrnsrivastava@yahoo.com
RI jain, amita/ABA-9223-2020
FU Council of Science and Technology, Uttar Pradesh
FX The authors are thankful to Dr. Rajendra P Mishra for his kind support.
   They are also thankful to the Council of Science and Technology, Uttar
   Pradesh, for the financial assistance.
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NR 27
TC 19
Z9 21
U1 0
U2 18
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD APR
PY 2016
VL 25
IS 4
BP 199
EP 207
DI 10.12968/jowc.2016.25.4.199
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA DJ2ON
UT WOS:000374044500005
PM 27064369
DA 2026-07-24
ER

PT J
AU Borgquist, O
   Anesäter, E
   Hedström, E
   Lee, CK
   Ingemansson, R
   Malmsjö, M
AF Borgquist, Ola
   Anesater, Erik
   Hedstrom, Erik
   Lee, Charles K.
   Ingemansson, Richard
   Malmsjo, Malin
TI Measurements of wound edge microvascular blood flow during negative
   pressure wound therapy using thermodiffusion and transcutaneous and
   invasive laser Doppler velocimetry
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MICROCIRCULATION; VALIDATION; GAUZE; FOAM
AB The effects of negative pressure wound therapy (NPWT) on wound edge microvascular blood flow are not clear. The aim of the present study was therefore to further elucidate the effects of NPWT on periwound blood flow in a porcine peripheral wound model using different blood flow measurement techniques. NPWT at -20, -40, -80, and -125 mmHg was applied to a peripheral porcine wound (n = 8). Thermodiffusion, transcutaneous, and invasive laser Doppler velocimetry were used to measure the blood perfusion 0.5, 1.0, and 2.5 cm from the wound edge. Thermodiffusion (an invasive measurement technique) generally showed a decrease in perfusion close to the wound edge (0.5 cm), and an increase further from the edge (2.5 cm). Invasive laser Doppler velocimetry showed a similar response pattern, with a decrease in blood flow 0.5 cm from the wound edge and an increase further away. However, 1.0 cm from the wound edge blood flow decreased with high pressure levels and increased with low pressure levels. A different response pattern was seen with transcutaneous laser Doppler velocimetry, showing an increase in blood flow regardless of the distance from the wound edge (0.5, 1.0, and 2.5 cm). During NPWT, both increases and decreases in blood flow can be seen in the periwound tissue depending on the distance from the wound edge and the pressure level. The pattern of response depends partly on the measurement technique used. The combination of hypoperfusion and hyperperfusion caused by NPWT may accelerate wound healing.
C1 [Borgquist, Ola] Lund Univ, Dept Anesthesiol & Intens Care, Lund, Sweden.
   [Borgquist, Ola; Anesater, Erik; Malmsjo, Malin] Lund Univ, Dept Ophthalmol, Lund, Sweden.
   [Borgquist, Ola; Anesater, Erik; Hedstrom, Erik; Ingemansson, Richard; Malmsjo, Malin] Skane Univ Hosp, Lund, Sweden.
   [Hedstrom, Erik] Lund Univ, Dept Clin Physiol, Lund, Sweden.
   [Lee, Charles K.] Univ Calif San Francisco, Div Plast & Reconstruct Surg, San Francisco, CA 94143 USA.
   [Ingemansson, Richard] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
C3 Lund University; Lund University; Lund University; Skane University
   Hospital; Lund University; University of California System; University
   of California San Francisco; Lund University
RP Malmsjö, M (通讯作者)，BMC A13, SE-22184 Lund, Sweden.
EM malin.malmsjo@med.lu.se
RI ; Borgquist, Ola/AAO-6451-2020
OI Maljö, Malin/0000-0001-9849-9599; Hedström, Erik/0000-0003-0041-9357;
   Ingemansson, Richard/0000-0001-7623-8953
FU Swedish Medical Research Council; Lund University Faculty of Medicine;
   Swedish Government Grant for Clinical Research; Lund University Hospital
   Research Grants; Swedish Medical Association; Royal Physiographic
   Society in Lund; Ake Wiberg Foundation; Anders Otto Sward
   Foundation/Ulrika Eklund Foundation; Magn Bergvall Foundation; Crafoord
   Foundation; Anna-Lisa and Sven-Erik Nilsson Foundation; Jeansson
   Foundation; Swedish Heart-Lung Foundation; Anna and Edvin Berger's
   Foundation; Marta Lundqvist Foundation; Lars Hierta Memorial Foundation
FX We thank Julia Waga for her invaluable assistance with the experimental
   work. This study was supported by the Swedish Medical Research Council,
   Lund University Faculty of Medicine, the Swedish Government Grant for
   Clinical Research, Lund University Hospital Research Grants, the Swedish
   Medical Association, the Royal Physiographic Society in Lund, the Ake
   Wiberg Foundation, the Anders Otto Sward Foundation/Ulrika Eklund
   Foundation, the Magn Bergvall Foundation, the Crafoord Foundation, the
   Anna-Lisa and Sven-Erik Nilsson Foundation, the Jeansson Foundation, the
   Swedish Heart-Lung Foundation, Anna and Edvin Berger's Foundation, the
   Marta Lundqvist Foundation, and the Lars Hierta Memorial Foundation.
   Marcom Medical ApS, Denmark, kindly supplied the O2C unit.
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NR 23
TC 47
Z9 56
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV
PY 2011
VL 19
IS 6
BP 727
EP 733
DI 10.1111/j.1524-475X.2011.00741.x
PG 7
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 840ZK
UT WOS:000296480900009
PM 22092843
DA 2026-07-24
ER

PT J
AU Xie, WW
   Dai, LY
   Qi, YM
   Jiang, XX
AF Xie, Weiwei
   Dai, Lingyan
   Qi, Yameng
   Jiang, Xixi
TI 被撤回的出版物: Negative pressure wound therapy compared with conventional
   wound dressings for closed incisions in orthopaedic trauma surgery: A
   meta-analysis (Retracted article. See vol. 22, 2025)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article; Retracted Publication
DE closed incisions; conventional wound dressing; length of hospital stay;
   negative pressure wound therapy; orthopaedic trauma surgery
ID SURGICAL-SITE INFECTION; IMPACT; FRACTURES; HIP
AB We performed a meta-analysis to evaluate the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery. A systematic literature search up to October 2021 was done and 12 studies included 3555 subjects with closed incisions in orthopaedic trauma surgery at the start of the study: 1833 of them were provided with negative pressure wound therapy and 1722 were conventional wound dressings. They were reporting relationships about the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery. We calculated the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) to assess the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery using the dichotomous and continuous methods with a random or fixed-effect model. Negative pressure wound therapy had significantly lower deep surgical site infection (OR, 0.65; 95% CI, 0.48-0.88, P = .005), superficial surgical site infection (OR, 0.23; 95% CI, 0.11-0.49, P = .31), and wound dehiscence (OR, 0.41; 95% CI, 0.21-0.80, P = .009) compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. However, negative pressure wound therapy had no significant effect on the length of hospital stay (MD, 0.29; 95% CI, -2.00- 2.58, P = .80) compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. Negative pressure wound therapy had significantly lower deep surgical site infection, superficial surgical site infection, and wound dehiscence; however, negative pressure wound therapy had no beneficial effect on the length of hospital stay compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. Further studies are required to validate these findings.
C1 [Xie, Weiwei; Jiang, Xixi] First Peoples Hosp Wenling, Dept Operat Room, Wenling 317500, Zhejiang, Peoples R China.
   [Dai, Lingyan] Huazhong Univ Sci & Technol, Ambulatory Surg Ctr, Wuhan Childrens Hosp, Tongji Med Coll,Wuhan Maternal & Childrens Health, Wuhan, Peoples R China.
   [Qi, Yameng] Tianjin Med Univ, Dept Dermatol, Hosp 2, Tianjin, Peoples R China.
C3 Huazhong University of Science & Technology; Tianjin Medical University
RP Jiang, XX (通讯作者)，First Peoples Hosp Wenling, Dept Operat Room, Wenling 317500, Zhejiang, Peoples R China.
EM jiangxixi2021@outlook.com@outlook.com
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NR 43
TC 16
Z9 18
U1 0
U2 15
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2022
VL 19
IS 6
BP 1319
EP 1328
DI 10.1111/iwj.13726
EA DEC 2021
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 4T2LH
UT WOS:000724806300001
PM 34854236
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Lindstedt, S
   Malmsjö, M
   Ingemansson, R
AF Lindstedt, Sandra
   Malmsjo, Malin
   Ingemansson, Richard
TI Effects on drainage of the mediastinum and pleura during negative
   pressure wound therapy when using a rigid barrier to prevent heart
   rupture
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Drainage; Experimental; Negative wound pressure therapy; Post sternotomi
   mediastinitis; Wound closure
ID VACUUM-ASSISTED CLOSURE; LONG-TERM SURVIVAL; POSTSTERNOTOMY
   MEDIASTINITIS; CARDIAC-SURGERY; INFECTION
AB Right ventricular heart rupture is a devastating complication associated with negative pressure wound therapy (NPWT) following cardiac surgery. The use of a rigid disc has been suggested to offer protection against this lethal complication by preventing the heart from being drawn up towards, and damaged by, the sharp sternum edges. The aim of the present study was to compare the wound fluid evacuation from the pericardium and the left pleura when using NPWT with such a disc between the sternal edges and the heart, and when using conventional NPWT. Six pigs underwent median sternotomy followed by NPWT at - 120 mmHg, using foam, with or without a rigid plastic disc between the heart and the sternal edges. A 250 ml saline was infused into the pericardium, and the time required for fluid evacuation was measured. A 500 ml saline was infused into the left pleura and the time for fluid evacuation measured. The pericardium was effectively drained of 250 ml fluid in both cases [conventional NPWT: 24 +/- 0.7 seconds, NPWT with the disc: 25 +/- 1.1 seconds (n.s.)]. The left pleura was effectively drained when using NPWT with the disc, but was not drained at all when using conventional NPWT. The left pleura could be effectively drained of 500 ml fluid when a rigid perforated plastic disc was inserted between the sternal edges and the heart during NPWT. Significantly less drainage of the left pleura was possible when using conventional NPWT without the disc. The pericardium was equally good drained using NPWT with or without the disc.
C1 [Lindstedt, Sandra] Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, SE-22185 Lund, Sweden.
   [Malmsjo, Malin] Univ Lund Hosp, Dept Ophthalmol, SE-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital
RP Lindstedt, S (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, SE-22185 Lund, Sweden.
EM sandra.lindstedt@skane.se
RI ; Lindstedt, Sandra/AEM-2892-2022
OI Ingemansson, Richard/0000-0001-7623-8953; Maljö,
   Malin/0000-0001-9849-9599; Lindstedt, Sandra/0000-0003-4484-6473
CR Abu-Omar Y, 2003, ANN THORAC SURG, V76, P974, DOI 10.1016/S0003-4975(03)00180-2
   Braxton JH, 2000, ANN THORAC SURG, V70, P2004, DOI 10.1016/S0003-4975(00)01814-2
   Braxton John H, 2004, Semin Thorac Cardiovasc Surg, V16, P70
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   Fleck Tatjana, 2006, Int Wound J, V3, P273, DOI 10.1111/j.1742-481X.2006.00273.x
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
   Khoynezhad A, 2004, J CARDIAC SURG, V19, P74, DOI 10.1111/j.0886-0440.2004.04015.x
   Malmsjö M, 2007, PLAST RECONSTR SURG, V120, P1266, DOI 10.1097/01.prs.0000279326.84535.2d
   Malmsjö M, 2009, J THORAC CARDIOV SUR, V138, P712, DOI 10.1016/j.jtcvs.2008.11.068
   Petzina R, 2007, J THORAC CARDIOV SUR, V133, P1154, DOI 10.1016/j.jtcvs.2007.01.011
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjögren J, 2005, ANN THORAC SURG, V80, P1270, DOI 10.1016/j.athoracsur.2005.04.010
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Sjogren Johan, 2004, Interact Cardiovasc Thorac Surg, V3, P666, DOI 10.1016/j.icvts.2004.08.003
NR 15
TC 4
Z9 4
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2011
VL 8
IS 5
BP 454
EP 458
DI 10.1111/j.1742-481X.2011.00816.x
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 822EG
UT WOS:000295026100004
PM 21692991
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Portou, MJ
   Collinsworth, AW
   Lookess, S
AF Portou, Mark J.
   Collinsworth, Ashley W.
   Lookess, Siobhan
TI Accelerating Patient Transitions From Hospital to Home in the United
   Kingdom With Single-Use Negative Pressure Wound Therapy: A Discharge
   Pathway
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE discharge pathway; wound healing; community; health services; health
   care costs; cost savings
ID VACUUM-ASSISTED CLOSURE; COSTS; CARE; RECOMMENDATIONS; MANAGEMENT;
   LENGTH; IMPACT
AB Background. Initially limited to inpatient use, negative pressure wound therapy (NPWT) is now frequently used in community settings. However, complexities in wound management step-down strategies in the United Kingdom, including regional variations in referral processes, lack of consensus on funding criteria, and limited availability of NPWT units, have led to extended hospital length of stay (LOS) for patients ready for discharge but still needing NPWT. Single-use NPWT (sNPWT) can serve as a bridge between hospital and community NPWT. Objective. To assess the feasibility, effectiveness, and potential cost savings of the implementation of a discharge pathway utilizing sNPWT. Methods. This case series included 5 patients with open lower limb wounds treated at a National Health Service facility using an sNPWT discharge pathway. Wounds were assessed before and after sNPWT use. Differences in average inpatient LOS and costs were calculated and compared with those for patients who remained hospitalized until community NPWT was available. Results. The sNPWT discharge pathway was well tolerated by patients and resulted in good clinical outcomes. Patients discharged on sNPWT had an average reduction in LOS of 20.2 days, resulting in a projected 12 pound 350 savings in hospital costs per patient. Conclusion. Preliminary findings indicate use of an sNPWT discharge pathway is feasible and may result in reduced LOS and associated costs while improving patient care. Additional studies are needed to understand the effect on wound management, patient outcomes, and overall care costs.
C1 [Portou, Mark J.] Royal Free London NHS Fdn Trust, London, England.
   [Collinsworth, Ashley W.; Lookess, Siobhan] Solventum, Maplewood, MN USA.
C3 University of London; University College London; Royal Free London NHS
   Foundation Trust
RP Collinsworth, AW (通讯作者)，12930 W Interstate 10, San Antonio, TX 78249 USA.
EM acollinsworth@solventum.com
CR Anchalia Manjulata, 2020, Wounds, V32, pE84
   Apelqvist J, 2008, AM J SURG, V195, P782, DOI 10.1016/j.amjsurg.2007.06.023
   Boti L, 2022, WOUNDS, V34, pE118, DOI 10.25270/wnds/22050
   Collinsworth AW, 2022, WOUNDS, V34, P269, DOI 10.25270/wnds/22013
   Diehm YF, 2020, INT WOUND J, V17, P1740, DOI 10.1111/iwj.13462
   Dowsett C, 2012, INT WOUND J, V9, P544, DOI 10.1111/j.1742-481X.2011.00913.x
   Driver VR, 2014, J AM PODIAT MED ASSN, V104, P147, DOI 10.7547/0003-0538-104.2.147
   2024, Journal of Wound Management Official journal of the European Wound Management Association, DOI [10.35279/jowm2024.25.02.sup01, 10.35279/jowm2024.25.02.sup01, DOI 10.35279/JOWM2024.25.02.SUP01]
   Fagerdahl A, 2023, J Wound Management, V24, P3
   Gabriel A., 2014, Eplasty, V14
   Guest JF, 2020, BMJ OPEN, V10, DOI 10.1136/bmjopen-2020-045253
   Guest JF, 2018, INT WOUND J, V15, P43, DOI 10.1111/iwj.12816
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Hurd T, 2021, WOUNDS, V33, pS1
   Kaplan M, 2009, ADV SKIN WOUND CARE, V22, P128, DOI 10.1097/01.ASW.0000305451.71811.d5
   Kim PJ, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9047
   Kirsner RS, 2020, WOUNDS, V32, P328
   Miller-Mikolajczyk C, 2024, ADV WOUND CARE, V13, P375, DOI 10.1089/wound.2023.0115
   Monsen C, 2017, J CLIN NURS, V26, P1405, DOI 10.1111/jocn.13702
   Murdoch Julie, 2021, Journal of Community Nursing, V35, P50
   National Health Service, 2023, Delivery Plan for Recovering Urgent and Emergency Care Services
   Neale A, 2017, BRIT J GEN PRACT, V67, P370, DOI 10.3399/bjgp17X692069
   Orlov A, 2022, INT WOUND J, V19, P1471, DOI 10.1111/iwj.13744
   Rojas-García A, 2018, HEALTH EXPECT, V21, P41, DOI 10.1111/hex.12619
   Santosa KB, 2020, J SURG RES, V254, P197, DOI 10.1016/j.jss.2020.04.025
   Sen CK, 2023, ADV WOUND CARE, V12, P657, DOI 10.1089/wound.2023.0150
   Tipton K., 2021, AHRQ Comparative Effectiveness Technical Briefs. In- terventions To Decrease Hospital Length of Stay.
   Warner M., 2024, The past and future of NHS waiting lists in England
NR 28
TC 0
Z9 0
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD AUG
PY 2025
VL 37
IS 8
BP 305
EP 313
DI 10.25270/wnds/24202
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 7HE1W
UT WOS:001570925400004
PM 40931370
DA 2026-07-24
ER

PT J
AU Pruitt, H
   Watson, AB
   Jennings, JA
   Bumgardner, JD
AF Pruitt, Haley
   Watson, Andrew Blass
   Jennings, J. Amber
   Bumgardner, Joel D.
TI Development of a Benchtop Model for Evaluating the Compatibility of
   Wound Dressing Materials with Negative Pressure Wound Therapy Systems
SO JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MEMBRANE; LAYER
AB Negative pressure wound therapy (NPWT) systems facilitate wound healing by applying sub-atmospheric pressure to the wound bed, which promotes granulation tissue formation and reduces inflammation. Wound dressings can be used with these systems to enhance healing; however, the effects of dressings on NPWT device performance are challenging to assess. The purpose of this study was to develop a benchtop flesh analog model for testing the compatibility of wound dressing materials with NPWT devices. In this study, a chitosan-based advanced wound care device was evaluated for its effects on NPWT performance under maximum and minimum therapy pressures. The goal was to use the model to compare pressure readings and fluid collection for samples with and without the chitosan wound care device. The benchtop model was constructed using a plastic box connected to multiple pressure gauges. A circular defect was created on a piece of pork belly, used as the flesh analog, and inserted into the box. The defect was filled with standard NPWT foam or foam combined with the wound dressing. Simulated body fluid containing bovine serum was added to the box, which was then tested at either maximum (-200 mmHg) or minimum (-25 mmHg) pressures for 72 h. Pressure and fluid collection were recorded every 12 h. The NPWT system successfully maintained pressure over the 72 h test period, both with and without the test dressings. The addition of the wound dressings did not impact fluid collection. The test box proved effective as a benchtop model, as it could be sealed and maintained vacuum conditions over the 72 h testing period. This model successfully demonstrated its utility in evaluating the compatibility of wound dressing materials with NPWT systems.
C1 [Pruitt, Haley; Watson, Andrew Blass; Jennings, J. Amber; Bumgardner, Joel D.] Univ Tennessee, Univ Memphis, Hlth Sci Ctr, Joint Grad Biomed Engn Program, Memphis, TN 38163 USA.
C3 University of Tennessee System; University of Tennessee Health Science
   Center; University of Memphis
RP Pruitt, H (通讯作者)，Univ Tennessee, Univ Memphis, Hlth Sci Ctr, Joint Grad Biomed Engn Program, Memphis, TN 38163 USA.
EM hnpruitt@memphis.edu
RI ; Watson, Andrew/OFN-2560-2025; Jennings, Jessica/PGM-2543-2026
OI Bumgardner, Joel/0000-0002-7467-3078; Jennings, Jessica
   Amber/0000-0002-2760-6948; 
FU University of Memphis Department of Biomedical Engineering and Bionova
   Medical
FX This research was made possible with the help of the University of
   Memphis Department of Biomedical Engineering and Bionova Medical.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Birke-Sorensen H, 2011, J PLAST RECONSTR AES, V64, pS1, DOI 10.1016/j.bjps.2011.06.001
   Burkatovskaya M, 2006, BIOMATERIALS, V27, P4157, DOI 10.1016/j.biomaterials.2006.03.028
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   Loveluck John, 2016, Eplasty, V16, pe20
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   Ren YH, 2017, INT J BURNS TRAUMA, V7, P12
   Rycerz AM, 2013, INT WOUND J, V10, P20, DOI 10.1111/iwj.12171
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
NR 15
TC 0
Z9 0
U1 0
U2 2
PU JOURNAL OF VISUALIZED EXPERIMENTS
PI CAMBRIDGE
PA 1 ALEWIFE CENTER, STE 200, CAMBRIDGE, MA 02140 USA
SN 1940-087X
J9 JOVE-J VIS EXP
JI J. Vis. Exp.
PD MAY
PY 2025
IS 219
AR E67890
DI 10.3791/67890
PG 16
WC Multidisciplinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Science & Technology - Other Topics
GA 4DU5Y
UT WOS:001515632000004
PM 40388354
DA 2026-07-24
ER

PT J
AU Davey, JS
   Chong, WL
   Fountain, J
   Heller, J
   Sul, R
   Jermyn, K
   Michelsen, J
   Eckart, LH
AF Davey, Jack S.
   Chong, Wye Li
   Fountain, Jake
   Heller, Jane
   Sul, Rui
   Jermyn, Kieri
   Michelsen, Jacob
   Eckart, Louisa Ho
TI In vitro evaluation of a hybrid negative pressure system for wound
   therapy
SO VETERINARY SURGERY
LA English
DT Article
ID MICROVASCULAR BLOOD-FLOW; VACUUM-ASSISTED CLOSURE; INTERMITTENT
AB ObjectiveThe objective of this study was to assess whether negative pressure could be maintained accurately and repeatably with a wall-suction-based hybrid negative pressure wound therapy (h-NPWT) system by comparing it with a commercial negative pressure wound therapy (NPWT) device.Study designIn vitro experimental study.MethodsA commercial NPWT device (control) and three h-NPWT devices, with 0, 3, and 6 meters of additional tubing using the hospital-wall suction (groups 1, 2, and 3 respectively), were applied sequentially to a commercial NPWT dressing on a silicone skin substrate and set to run at a continuous pressure of -125 mmHg. The pressure within the wound space was monitored at 10 second intervals for 24 h. The process was repeated five times for each group.ResultsThe commercial NPWT device produced an average pressure variance of 3.02 mmHg, and the h-NPWT produced average variances of 4.38, 4.24 and 4.20 mmHg for groups 1, 2 and 3, respectively. All groups produced an average pressure within 0.15 mmHg of -125 mmHg over the 24-hour period, and the h-NPWT systems produced the smallest range with all values remaining within a +/- 5% variation from -125 mmHg.ConclusionThe h-NPWT system achieved negative pressures that were comparable to those of a commercial control NPWT device. The addition of tubing between the skin substrate and the canister did not affect the pressure applied at the wound site.Clinical significanceThe h-NPWT device tested in this study can be considered as an alternative for negative wound therapy when a commercial device cannot be used.
C1 [Davey, Jack S.; Chong, Wye Li; Sul, Rui; Jermyn, Kieri; Michelsen, Jacob; Eckart, Louisa Ho] Anim Referral Hosp Canberra, 364 Fairbairn Ave, Pialligo, ACT 2609, Australia.
   [Davey, Jack S.; Fountain, Jake; Heller, Jane] Charles Sturt Univ, Fac Sci & Hlth, Sch Agr Environm & Vet Sci, Wagga Wagga, NSW, Australia.
C3 Charles Sturt University
RP Davey, JS (通讯作者)，Anim Referral Hosp Canberra, 364 Fairbairn Ave, Pialligo, ACT 2609, Australia.
EM j.davey@arhvets.com
RI Michelsen, Jacob/KBC-6638-2024; Fountain, Jake/JVE-2235-2024; Heller,
   Jane/H-9596-2016
OI Michelsen, Jacob/0009-0000-5567-9637; Sul, Rui/0009-0001-8339-8039;
   Davey, Jack/0000-0001-7302-5215; Ho Eckart, Louisa/0009-0003-7428-7067;
   Fountain, Jake/0000-0002-9416-5900; Heller, Jane/0000-0003-3993-0160;
   Chong, Wye Li/0000-0001-6697-3073
CR 3M, SENSATRAC PAD 3M SCI
   Ahearn C, 2009, OSTOMY WOUND MANAG, V55, P22
   Banwell P E, 1999, J Wound Care, V8, P79
   Birke-Sorensen H, 2011, J PLAST RECONSTR AES, V64, pS1, DOI 10.1016/j.bjps.2011.06.001
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   Borgquist O, 2011, OSTOMY WOUND MANAG, V57, P44
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   Borgquist O, 2010, OSTOMY WOUND MANAG, V56, P60
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NR 22
TC 0
Z9 1
U1 1
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0161-3499
EI 1532-950X
J9 VET SURG
JI Vet. Surg.
PD AUG
PY 2024
VL 53
IS 6
BP 1093
EP 1101
DI 10.1111/vsu.14101
EA MAY 2024
PG 9
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA C7I8W
UT WOS:001222530600001
PM 38747194
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Gupta, S
   Srivastava, A
   Malhotra, R
   Chadha, M
   Aggarwal, AN
AF Gupta, Saurabh
   Srivastava, Amit
   Malhotra, Raskesh
   Chadha, Manish
   Aggarwal, Aditya N.
TI Wound Assessment Using Bates Jensen Wound Assessment Tool in Acute
   Musculoskeletal Injury Following Low-Cost Wall-Mounted Negative-Pressure
   Wound Therapy Application
SO INDIAN JOURNAL OF ORTHOPAEDICS
LA English
DT Article
DE Negative-pressure wound therapy; Wound assessment score; Low cost; Open
   wounds; Vacuum-assisted closure
ID VACUUM-ASSISTED CLOSURE; ULCERS
AB BackgroundNegative-pressure wound therapy (NPWT) is an alternative method of wound management for spontaneous healing. However, availability and high cost of a conventional NPWT system remain a challenge. Bates Jensen wound assessment tool (BWAT) has been used to assess wound healing in diverse wound treatments. Although there have been studies evaluating change in BWAT score following application of commercially available NPWT device, there is no literature evaluating change in BWAT score following use of wall-mounted low-cost NPWT device.Materials and MethodsTwenty patients above the age of 18 years with acute musculoskeletal wounds who underwent surgical debridement and required subsequent wound coverage were included in the study. Wound dressings were carried out using low-cost wall-mounted negative-pressure device utilizing a constant pressure of 125 mmHg for 48 h. Wound scoring was done using the Bates Jensen wound assessment tool (BWAT). The wound scores before and after application of NPWT were compared and analyzed using Wilcoxon signed-rank test.ResultsTwenty patients fulfilling the inclusion criteria with a mean age of 37.10 +/- 14.37 were included in the study. The average BWAT score before and after NPWT application was 31.2 +/- 4.63 and 27.8 +/- 3.68, respectively. The mean reduction in total BWAT score following NPWT application was 3.4. The granulation profile improved in 90% (n = 18/20) cases with a mean reduction of 1.5 +/- 0.4 in the granulation tissue score. Exudation decreased in 60% (n = 12/20) patients with a mean reduction of 0.5 +/- 0.23 in exudation type score and 0.35 +/- 0.13 in exudation amount score. The necrotic tissue domain improved in 45% (n = 9/20) of the cases with a mean reduction of 0.45 +/- 0.31 in necrotic tissue type score and 0.20 +/- 0.12 in necrotic tissue amount score.ConclusionThere was a statistically significant reduction in the total BWAT score (p = 0.001) and an increase in granulation tissue (p = 0.001). The decrease in wound exudation (p = 0.004) and necrotic tissue coverage of the wound (p = 0.007) was also significant. However, there was no statistically significant change in wound depth, size, edges, undermining, tissue edema, tissue induration, and wound epithelialization after 48 h of continuous low-cost wall-mounted negative suction application in these patients.
C1 [Gupta, Saurabh; Srivastava, Amit; Malhotra, Raskesh; Chadha, Manish; Aggarwal, Aditya N.] Univ Coll Med Sci, Guru Teg Bahadur Hosp, Dept Orthopaed, Delhi 110095, India.
   [Srivastava, Amit] D-56 New Ashok Nagar, Delhi 110096, India.
C3 University of Delhi; University College of Medical Sciences
RP Srivastava, A (通讯作者)，Univ Coll Med Sci, Guru Teg Bahadur Hosp, Dept Orthopaed, Delhi 110095, India.; Srivastava, A (通讯作者)，D-56 New Ashok Nagar, Delhi 110096, India.
EM saurabh.14796@gmail.com; amitsrvstv00@gmail.com; malhotraucms@gmail.com;
   mchadha@hotmail.com; dranaggarwal@hotmail.com
RI /AAS-4744-2021
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NR 24
TC 7
Z9 8
U1 0
U2 1
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0019-5413
EI 1998-3727
J9 INDIAN J ORTHOP
JI Indian J. Orthop.
PD JUN
PY 2023
VL 57
IS 6
BP 948
EP 956
DI 10.1007/s43465-023-00861-2
EA APR 2023
PG 9
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA G3IK8
UT WOS:000962664800001
PM 37214372
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Notorgiacomo, G
   Klug, J
   Rapp, S
   Boyce, ST
   Schutte, SC
AF Notorgiacomo, Gabrielle
   Klug, Justin
   Rapp, Scott
   Boyce, Steven T.
   Schutte, Stacey C.
TI A bioreactor for studying negative pressure wound therapy on skin grafts
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE bioreactor; NPWT; skin graft; skin substitute
ID VACUUM-ASSISTED CLOSURE; DRESSING METHODS; LEG ULCERS; SUBSTITUTES;
   INTEGRATION; MANAGEMENT; EFFICACY; DEVICE
AB Negative pressure wound therapy (NPWT) has become the prevailing standard of care for treating complex soft tissue wounds and is now being considered for use in alternative applications including improving skin graft take. While it is generally agreed that negative pressure leads to improved wound healing, universal consensus on its optimal application is not supported in the literature. We describe the design and validation of a bioreactor to determine the prospective benefits of NPWT on skin grafts and engineered skin substitutes (ESS). Clinically relevant pressures were applied, and the native human skin was able to withstand greater negative pressures than the engineered substitutes. Both skin types were cultured under static, flow-only, and -75 mm Hg conditions for 3 days. While it remained intact, there was damage to the epidermal-dermal junction in the ESS after application of negative pressure. The normal skin remained viable under all culture conditions. The engineered skin underwent apoptosis in the flow-only group; however, the application of negative pressure reduced apoptosis. Vascular endothelial growth factor levels were significantly higher in the normal flow-only group, 152.0 +/- 75.1 pg/mg protein, than the other culture conditions, 81.6 +/- 35.5 pg/mg for the static and 103.6 +/- pg/mg for the negative pressure conditions. The engineered skin had a similar trend but the differences were not significant. This bioreactor design can be used to evaluate the impacts of NPWT on the anatomy and physiology of skin to improve outcomes in wounds after grafting with normal or engineered skin.
C1 [Notorgiacomo, Gabrielle; Klug, Justin; Schutte, Stacey C.] Univ Cincinnati, Dept Biomed Engn, Cincinnati, OH USA.
   [Rapp, Scott] Norton Childrens Hosp, Div Plast Surg, Louisville, KY USA.
   [Rapp, Scott] Kentucky Ctr Cosmet & Reconstruct Surg, Louisville, KY USA.
   [Rapp, Scott; Boyce, Steven T.; Schutte, Stacey C.] Shriners Hosp Children Cincinnati, Res Dept, Cincinnati, OH USA.
   [Boyce, Steven T.] Univ Cincinnati, Dept Surg, 231 Bethesda Ave, Cincinnati, OH 45267 USA.
C3 University System of Ohio; University of Cincinnati; University System
   of Ohio; University of Cincinnati
RP Schutte, SC (通讯作者)，2901 Woodside Dr,501 Engn Res Ctr, Cincinnati, OH 45221 USA.
EM stacey.schutte@uc.edu
RI Schutte, Stacey/L-9039-2019
OI Schutte, Stacey/0000-0002-8092-5067
FU Shriners Hospitals for Children; University of Cincinnati
FX Shriners Hospitals for Children; University of Cincinnati
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NR 47
TC 6
Z9 6
U1 0
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAR
PY 2022
VL 19
IS 3
BP 633
EP 642
DI 10.1111/iwj.13661
EA JUL 2021
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA ZH2HY
UT WOS:000670390100001
PM 34235863
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Fernández, LG
   Matthews, MR
   Seal, L
AF Fernandez, Luis G.
   Matthews, Marc R.
   Seal, Lawton
TI Intraabdominal Lavage of Hypochlorous Acid: A New Paradigm for the
   Septic and Open Abdomen
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE hypochlorous acid; open abdomen; intraabdominal lavage; negative
   pressure wound therapy; temporary abdominal closure; instillation; acute
   wound
ID PRESSURE WOUND THERAPY; VACUUM-ASSISTED CLOSURE; DAMAGE-CONTROL;
   CLINICAL RECOMMENDATIONS; ABDOMINAL SEPSIS; MANAGEMENT; INSTILLATION;
   IMPACT; GUIDELINES; MULTICENTER
AB Introduction. Management of the open abdomen (OA) has rapidly evolved over the last several decades due to the improved understanding of the underlying pathophysiolog of patients with an OA, adoption of damage control surgery, and the use of temporary abdominal closure has been (TAC) techniques for this patient population. The TAC utilizing negative pressure successful managing patients with an OA with improved time to closure. Recent studies have started to examine the use of TAC in conjunction with negative pressure wound therapy with instillation and dwell time (NPWTi-d) for the management of the OA Objective. This case series illustrates the capability, safety, and clinical effectiveness of TAC/NPWTi-d with hypochlorous acid (HOCI) solution. Materials and Methods. Three successfully treated cases describe the use of NPWTi-d using HOCI solution for the management of patients with a septic OA. Results. This initial experience suggests instillation of HOCI through the tubing set, in conjunction with the TAC device, is safe and easy to use. This technique decreased the need for more frequent OA lavages in the operating room (OR) after the index procedure, as well as the associated concomitant risks of transporting patients who are critically ill between the SICU and OR. No acute complications related to the TAC device with HOCI were noted. Conclusions. Based on the results of this study, the authors believe instillation through the TAC device may be the next evolution in the use of abdominal NPWT and programmed intermittent lavage of the peritoneal cavity represents an effective method in the care of patients with a septic OA.
C1 [Fernandez, Luis G.] Univ Texas Hlth Ctr Tyler, Tyler, TX USA.
   [Matthews, Marc R.] Maricopa Integrated Hlth Syst, Phoenix, AZ USA.
   [Seal, Lawton] Univ North Texas, Denton, TX 76203 USA.
C3 University of Texas System; University of Texas-Health Sciences Center
   at Tyler (UTHSCT); Maricopa County General Hospital; Maricopa Integrated
   Health System; University of North Texas System; University of North
   Texas Denton
RP Fernández, LG (通讯作者)，UT Hlth East Texas Phys Tyler, Surg, Dept Surg, 6801 Hollytree Cirde, Tyler, TX 75703 USA.
EM thebigkahuna115@gmail.com
RI FERNANDEZ, LUIS/O-7657-2019
OI FERNANDEZ, LUIS/0000-0002-2730-0199
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NR 67
TC 11
Z9 14
U1 0
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2020
VL 32
IS 4
BP 107
EP 114
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA NF1CR
UT WOS:000563040100004
PM 32155118
DA 2026-07-24
ER

PT J
AU De Martino, A
   Del Re, F
   Falcetta, G
   Morganti, R
   Ravenni, G
   Bortolotti, U
AF De Martino, Andrea
   Del Re, Federico
   Falcetta, Giosue
   Morganti, Riccardo
   Ravenni, Giacomo
   Bortolotti, Uberto
TI Sternal Wound Complications: Results of Routine Use of Negative Pressure
   Wound Therapy
SO BRAZILIAN JOURNAL OF CARDIOVASCULAR SURGERY
LA English
DT Article
DE Sternotom; Patient Discharge; Duration of Therapy; Sternum;
   Hospitalization, Infections; Postoperative Complications
ID VACUUM-ASSISTED CLOSURE; PRACTICE GUIDELINE SERIES; RISK-FACTORS;
   CARDIAC-SURGERY; INFECTIONS; MANAGEMENT; IMPACT; MEDIASTINITIS;
   SURVIVAL; SOCIETY
AB Introduction: Negative pressure wound therapy (NPWT) has significantly improved outcomes in individuals with superficial and deep sternal wound dehiscence (SWD). We report our experience with NPWT to evaluate factors influencing effectiveness, duration of treatment and postoperative hospital stay.
   Methods: We reviewed 92 patients with postoperative SWD following a median sternotomy. Patients were divided into 2 groups: those with a superficial SWD (Group 1; 72, 78%) and those with a deep SWD (Group 2; 20, 28%). Group 1 was further divided into 3 subgroups based on NPWT duration.
   Results: In both groups, none of the preoperative characteristics examined showed a significant association with longer NPWT duration. In Group 2, there was a trend for postoperative bleeding and neurological complications to be associated with longer treatment duration. In the entire series, staph infection resulted a weak predictor of NPWT duration. In each Group 1 subgroup and in Group 2, treatment days were compared with duration of hospitalization until discharge. Mean post-NPWT hospital stay was 6 days in subgroup 1, 12 days in subgroup 2 and 20 days in subgroup 3 (P<0.0001). At a median 3-year follow-up, there were 4 late deaths, none related to wound complications. No cases of SWD recurrence were observed.
   Conclusion: Our results confirm the effectiveness of NPWT in SWD management, while excessive treatment duration might have a negative impact on the length of hospital stay. Further studies are needed to define an optimal use of NPWT protocol.
C1 [De Martino, Andrea; Del Re, Federico; Falcetta, Giosue; Ravenni, Giacomo; Bortolotti, Uberto] Univ Hosp, Sect Cardiac Surg, Pisa, Italy.
   [Morganti, Riccardo] Univ Hosp, Sect Stat, Pisa, Italy.
   [De Martino, Andrea; Del Re, Federico; Falcetta, Giosue; Morganti, Riccardo; Ravenni, Giacomo; Bortolotti, Uberto] Univ Hosp, Pisa, Italy.
C3 University of Pisa; Azienda Ospedaliero Universitaria Pisana; University
   of Pisa; Azienda Ospedaliero Universitaria Pisana; University of Pisa;
   Azienda Ospedaliero Universitaria Pisana
RP De Martino, A (通讯作者)，Univ Pisa, Sez Autonoma Cardiochirurg Univ, Via Paradisa 2, I-56124 Pisa, Italy.
EM andrea.demartino@unipi.it
RI De Martino, Andrea/M-6415-2019
OI De Martino, Andrea/0000-0003-2889-4918
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 25
TC 9
Z9 11
U1 0
U2 2
PU SOC BRASIL CIRURGIA CARDIOVASC
PI SAO PAULO SP
PA RUA AFONSO CELSO, 1178, SAO PAULO SP, 04119-061, BRAZIL
SN 0102-7638
EI 1678-9741
J9 BRAZ J CARDIOVA SURG
JI Braz. J. Cardiovasc. Surg.
PY 2020
VL 35
IS 1
BP 50
EP 57
DI 10.21470/1678-9741-2019-0242
PG 8
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA KS3MJ
UT WOS:000518215300011
PM 32270960
OA Green Submitted, Green Published, gold
DA 2026-07-24
ER

PT J
AU Masters, JPM
   Achten, J
   Cook, J
   Dritsaki, M
   Sansom, L
   Costa, ML
AF Masters, James P. M.
   Achten, Juul
   Cook, Jonathan
   Dritsaki, Melina
   Sansom, Lucy
   Costa, Matthew L.
TI Randomised controlled feasibility trial of standard wound management
   versus negative-pressure wound therapy in the treatment of adult
   patients having surgical incisions for hip fractures
SO BMJ OPEN
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; SITE INFECTION; RISK-FACTORS; SURVEILLANCE;
   MORTALITY
AB Introduction Deep wound infection is a catastrophic complication after hip fracture surgery. However, current understanding of infection rates in this population is limited. Many technologies such as incisional negative-pressure wound therapy (NPWT) show promise in reducing the rate of infection. This trial is a feasibility study looking to establish a value estimated with a greater precision of the rate of deep infection after hip fracture treatment in patients treated with NPWT versus standard dressing following hip fracture surgery.
   Methods and analysis A randomised controlled trial of 464 patients will be run across multiple centres. It is embedded in the World Hip Trauma Evaluation cohort study. Any patient over the age of 65 years having surgery for hip fracture is eligible unless they are being treated with percutaneous screw fixation. A web-based randomisation sequence will stratify patients by centre. Patients will be allocated to either NPWT or standard care on a 1: 1 basis. The primary outcome measure is the Centre for Disease Control definition of deep infection at 30 days. Follow-up at 4 months will also assess deep infection and the core outcome dataset for hip fractures. This includes health-related quality of life (EQ-5D-5L), mobility, mortality and late complications such as further surgery. The primary analysis will be intention to treat.
   Ethics and dissemination Oxford C Research Ethics Committee granted ethical approval on 28/04/2017, 17/SC/0207. The results of this study will be reported in a peer-reviewed publication and inform the design of a future full-scale trial.
C1 [Masters, James P. M.; Achten, Juul; Sansom, Lucy; Costa, Matthew L.] Univ Oxford, Oxford Trauma, NDORMS, Oxford, England.
   [Cook, Jonathan] Univ Oxford, Ctr Stat Med, NDORMS, Oxford, England.
   [Dritsaki, Melina] Univ Oxford, Oxford Clin Trial Unit, NDORMS, Oxford, England.
C3 University of Oxford; University of Oxford; University of Oxford
RP Masters, JPM (通讯作者)，Univ Oxford, Oxford Trauma, NDORMS, Oxford, England.
EM james.masters@ndorms.ox.ac.uk
RI Masters, James/U-8764-2019; Cook, Jonathan/D-3648-2015; Achten,
   Juul/KUD-8515-2024
OI Masters, James/0000-0001-9663-8858; Cook, Jonathan/0000-0002-4156-6989;
   Achten, Juul/0000-0002-8857-5743; Costa, Matthew/0000-0003-3644-1388
FU Royal College of Surgeons of England; Dunhill Medical Trust
   [DMT/RCS605]; National Institute for Health Research (NIHR) Oxford
   Biomedical Research Centre; MRC [MR/K025643/1] Funding Source: UKRI;
   Medical Research Council [MR/K025643/1] Funding Source: researchfish;
   National Institute for Health Research [14/199/14, NF-SI-0514-10114]
   Funding Source: researchfish; The Dunhill Medical Trust [DMT/RCS605]
   Funding Source: researchfish
FX The study is funded by the Royal College of Surgeons of England and The
   Dunhill Medical Trust [DMT/RCS605]. It is supported by the National
   Institute for Health Research (NIHR) Oxford Biomedical Research Centre.
   Excess treatment costs for the negative pressure wound therapy arm of
   the study are met by Smith and Nephew.
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NR 28
TC 13
Z9 14
U1 0
U2 9
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 2044-6055
J9 BMJ OPEN
JI BMJ Open
PD APR
PY 2018
VL 8
IS 4
AR e020632
DI 10.1136/bmjopen-2017-020632
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GJ3FT
UT WOS:000435176700181
PM 29654039
OA Green Submitted, Green Accepted, gold
DA 2026-07-24
ER

PT J
AU Miller-Mikolajczyk, C
   Beach, K
   Silverman, R
   Cooper, M
AF Miller-Mikolajczyk, Cynthia
   Beach, Karen
   Silverman, Ronald
   Cooper, Matthew
TI The Evolution of Commercial Negative Pressure Wound Therapy Systems over
   the Past Three Decades
SO ADVANCES IN WOUND CARE
LA English
DT Review
DE NPWT; history of NPWT; wound care; NPWT technology; NPWT innovation
ID VACUUM-ASSISTED CLOSURE; OPEN-CELL FOAM; RANDOMIZED CONTROLLED-TRIAL;
   VENOUS LEG ULCERS; INSTILLATION; BACTERIAL; MANAGEMENT; BIOBURDEN;
   RECOMMENDATIONS; COMPLICATIONS
AB Significance: Since the introduction of the first commercial negative pressure wound therapy (NPWT) system nearly three decades ago, several key technological innovations have led to the wide adoption of the therapy. This is a review of the history and innovation of commercial NPWT systems for adjunctive management of open wounds.Recent Advances: Technical modifications have broadened NPWT options to include innovative dressing interfaces, tubing configurations, power sources, capability of topical wound solution instillation or irrigation, canister versus canister-free configurations, smart technology, and disposable versus larger reusable therapy units. While these options complicate product selection, they have greatly expanded the potential to manage a wide variety of wounds in patients who previously may not have been candidates for NPWT.Critical Issues: Basic yet mandatory requirements of NPWT include delivering an accurate level of negative pressure to the wound bed, maintaining a seal, removing wound surface exudate through the dressing interface, and patient adherence to prescribed therapy. Meeting these requirements is challenging in the face of variable wound types, wound locations, exudate levels, and exudate viscosity. While there are a growing number of marketed NPWT systems, each may have different characteristics and performance. Evaluating the functionality of each system and relevant accessories is complicated, especially as additional manufacturers enter the market. Understanding the key innovations and specific challenges they are intended to solve may aid health care providers in selecting appropriate NPWT technologies for patients.Future Directions: Evolving technology, including artificial intelligence, will likely play a major role in redefining NPWT safety, simplicity, and reliability.
C1 [Miller-Mikolajczyk, Cynthia; Beach, Karen] 3M Healthcare, 9915 Fall Harvest, Minneapolis, MN 78254 USA.
   [Silverman, Ronald] Becton Dickinson & Co, Franklin, NJ USA.
   [Silverman, Ronald] Univ Maryland Med Syst, Baltimore, MD USA.
   [Cooper, Matthew] Peak Cardiovasc, Lake Elmo, MN USA.
C3 3M; Becton Dickinson; University System of Maryland; University of
   Maryland Baltimore
RP Miller-Mikolajczyk, C (通讯作者)，3M Healthcare, 9915 Fall Harvest, Minneapolis, MN 78254 USA.
EM Camiller3@mmm.com
RI ; Silverman, Ronald/A-5155-2018
OI Miller-Mikolajczyk, Cynthia/0009-0003-3162-2291; 
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NR 104
TC 10
Z9 10
U1 1
U2 11
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD AUG 1
PY 2024
VL 13
IS 8
BP 375
EP 390
DI 10.1089/wound.2023.0115
EA JUL 2024
PG 16
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA A7O0L
UT WOS:001263796500001
PM 38666695
OA hybrid
DA 2026-07-24
ER

PT J
AU Tanaydin, V
   Beugels, J
   Andriessen, A
   Sawor, JH
   van der Hulst, RRWJ
AF Tanaydin, V
   Beugels, J.
   Andriessen, A.
   Sawor, J. H.
   van der Hulst, R. R. W. J.
TI Randomized Controlled Study Comparing Disposable Negative-Pressure Wound
   Therapy with Standard Care in Bilateral Breast Reduction Mammoplasty
   Evaluating Surgical Site Complications and Scar Quality
SO AESTHETIC PLASTIC SURGERY
LA English
DT Article
DE Negative-pressure therapy; Post-mammoplasty; PICO; Scar; POSAS;
   Cutometer
ID VACUUM-ASSISTED CLOSURE; SKIN ELASTICITY METER; VISUAL ANALOG SCALE;
   CONTROLLED-TRIAL; SATISFACTION; MANAGEMENT; FRACTURES; PATIENT; TRAUMA
AB Background Negative pressure wound therapy (NPWT) for postsurgical incision treatment has demonstrated benefits. A prospective randomized study was developed including 32 patients who underwent bilateral breast reduction mammoplasty. Patients served as their own control and received NPWT to one breast and fixation strips to the other breast.
   Methods The primary outcome was the number of wound healing complications within 21 days when comparing NPWT treatment with fixation strips. The secondary outcome was aesthetic appearance and quality of scarring using questionnaires [visual analogue scale (VAS) and Patient and Observer Scar Assessment Scale (POSAS)] scored at day 42-, 90-, 180- and 365-day follow-up using additional scar measurement modalities, such as viscoelasticity.
   Results For the 32 included patients, the number of wound complications was significantly lower (p < 0.004) for the NPWT treated sites compared to fixation strips. POSAS and VAS scores at 42 and 90 days revealed a significantly better quality of scarring in the NPWT treatment breasts than in fixation strips. At 180-day follow-up, there was a significant improvement in VAS scores, as well as a comparable improvement in POSAS scores. No consistent significant improvement in scar quality was demonstrated with the assays that were used.
   Conclusions Our study showed less complications and a significant improvement in quality of scarring in favor of the NPWT-treated sites. The results indicate NPWT to be an attractive option for these patients.
C1 [Tanaydin, V; Beugels, J.; Sawor, J. H.; van der Hulst, R. R. W. J.] Maastricht Univ, Med Ctr, Maastricht, Netherlands.
   [Andriessen, A.] Andriessen Consultants, Malden, Netherlands.
   [Andriessen, A.] Radboud Univ Nijmegen Med Ctr, Nijmegen, Netherlands.
   [Sawor, J. H.; van der Hulst, R. R. W. J.] VieCuri Med Ctr, Venlo, Netherlands.
C3 Maastricht University; Radboud University Nijmegen; VieCuri Medical
   Center
RP Tanaydin, V (通讯作者)，Maastricht Univ, Med Ctr, Maastricht, Netherlands.
EM volkan.tanaydin@mumc.nl
FU Smith and Nephew Ltd.
FX This study was funded by Smith and Nephew Ltd., by providing the PICO
   dressings, the Cutometer and financing a research assistant for carrying
   out the assessments and measurements for the study.
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NR 35
TC 50
Z9 55
U1 1
U2 5
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0364-216X
EI 1432-5241
J9 AESTHET PLAST SURG
JI Aesthet. Plast. Surg.
PD AUG
PY 2018
VL 42
IS 4
BP 927
EP 935
DI 10.1007/s00266-018-1095-0
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GO9AV
UT WOS:000440395700001
PM 29442143
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Santarpino, G
   Pollari, F
   Fischlein, TJ
AF Santarpino, Giuseppe
   Pollari, Francesco
   Fischlein, Theodor J.
TI Sternal closure following negative pressure wound therapy: a safe
   approach with a new titanium device
SO INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
LA English
DT Article
DE Mediastinal infection; Wound closure; Wound dehiscence; Wound infection
ID VACUUM-ASSISTED CLOSURE; SURGICAL-SITE INFECTIONS; LONG-TERM SURVIVAL;
   POSTOPERATIVE MEDIASTINITIS; RISK-FACTORS; DEEP; IMPACT; SURGERY;
   SYSTEM; COMPLICATIONS
AB Background: The application of negative pressure wound therapy (NPWT) in patients with deep wound infection after cardiac surgery has steadily increased worldwide. Following NPWT, in patients with concomitant sternal diastasis, preparation of the substernal structures for the sternal wires application is mandatory, with increased risk of severe complications, such as laceration of the right ventricle. The aim of this study is to present an innovative technique for sternal closure after NPWT, using the ASCS r System (ASCS atraumatic Sternum Closure System; KS Handelsvertretung Produktinovation, Bad Homburg, Germany).
   Methods: Between January 2009 and August 2012, 88 patients (mean age 64.2 +/- 12.4 years) with deep wound infection and sternal diastasis received NPWT; 16 of these patients (18.2%) underwent sternal closure after NPWT with ASCS r.
   Results: In all 16 cases, neither sub-sternal dissection nor placement of trans-or peristernal wires was necessary. No damage to the aortocoronary bypass and ventricular rupture occurred. Minimal post-operative bleeding from Redon drains (mean 40 +/- 10 ml) was present. At follow-up, deep wound infection and sternal diastasis did not occur.
   Conclusions: The ASCS r System combined with NPWT in patients with postoperative deep wound infection and sternal diastasis is a feasible and safe procedure. Because preparation of the substernal structures is not necessary, this device might prevent the occurrence of severe complications. Our experience, however, is limited and larger case series are necessary to fully evaluate this new and innovative technique.
C1 [Santarpino, Giuseppe; Pollari, Francesco; Fischlein, Theodor J.] Klinikum Nurnberg, Dept Cardiac Surg, Nurnberg, Germany.
C3 Klinikum Nurnberg
RP Santarpino, G (通讯作者)，Klinikum Sud, Klinikum Nurnberg, Dept Cardiac Surg, Breslauerstr 201, D-90471 Nurnberg, Germany.
EM g.santarpino@libero.it
RI Santarpino, Giuseppe/H-8678-2013; Pollari, Francesco/Q-4656-2016
OI Santarpino, Giuseppe/0000-0002-4913-9834; Pollari,
   Francesco/0000-0003-1729-532X
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NR 25
TC 1
Z9 1
U1 0
U2 5
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 0391-3988
EI 1724-6040
J9 INT J ARTIF ORGANS
JI Int. J. Artif. Organs
PD MAR
PY 2014
VL 37
IS 3
BP 264
EP 269
DI 10.5301/ijao.5000295
PG 6
WC Engineering, Biomedical; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Transplantation
GA AK6CK
UT WOS:000338515100008
PM 24619892
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Dini, V
   Miteva, M
   Romanelli, P
   Bertone, M
   Romanelli, M
AF Dini, Valentina
   Miteva, Maria
   Romanelli, Paolo
   Bertone, Mariastefania
   Romanelli, Marco
TI Immunohistochemical Evaluation of Venous Leg Ulcers Before and After
   Negative Pressure Wound Therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; IMMUNOREACTIVITY; PATHOGENESIS; MECHANISMS;
   EXPRESSION; OXYGEN; D2-40
AB Venous leg ulcers represent a medical challenge. Whenever possible, therapy should be causal and include compression therapy and surgery. Negative pressure wound therapy (NPWT) has been successfully used in several phases of venous leg ulcer treatment. Positive effects of NPWT, such as reduction of edema, drainage of wound exudate, and acceleration of granulation tissue formation, are reasons for recommending NPWT in order to improve healing rates. Aim. The main goal of this study was to evaluate, using immunohistochemical markers, the efficacy of NPWT in terms of neoangiogenesis and granulation tissue promotion in the treatment of hard-to-heal venous leg ulcers. Methods. Thirty patients with hard-to-heal venous leg ulcers were included. The patients were divided into two groups: one group treated with NPWT, polyurethane foam, and four-layer bandaging system, and the second group with moist wound dressings and four-layer bandaging system. Patients were monitored before and after 1 week of treatment with multiple biopsies taken from the wound bed and wound edge. Immunohistochemical evaluation included markers for angiogenesis (CD31), lymphatic vessels (D240), macrophages (CD68), and lymphocytes (CD3). Results. All patients included in the NPWT group, after 1 week, showed a significant improvement in terms of angiogenesis, lymphatic vessels, and macrophage and lymphocyte proliferation, compared to the control group. Conclusion. This study objectively demonstrated the efficacy of NPWT in hard-to-heal venous leg ulcers via immunohistochemical findings. In particular, the results showed rapid granulation and neoangiogenesis promotion. In the authors' opinion, NPWT must be included as an adjuvant to standard venous leg ulcer therapy.
C1 [Dini, Valentina; Bertone, Mariastefania; Romanelli, Marco] Univ Pisa, Dept Dermatol, I-56126 Pisa, Italy.
   [Miteva, Maria; Romanelli, Paolo] Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA.
C3 University of Pisa; University of Miami
RP Romanelli, M (通讯作者)，Univ Pisa, Dept Dermatol, Via Roma 67, I-56126 Pisa, Italy.
EM m.romanelli@med.unipi.it
RI dini, valentina/F-7747-2017; romanelli, marco/ABI-1154-2020
OI dini, valentina/0000-0002-8537-1999; romanelli,
   marco/0000-0002-4127-0141
FU KCI International; SAWC Spring Young Investigator's Award
FX This study was supported by an unrestricted educational grant from KCI
   International. This research was based on Dr. Dini's abstract, which won
   the 2010 SAWC Spring Young Investigator's Award.
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NR 29
TC 6
Z9 8
U1 0
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD SEP
PY 2011
VL 23
IS 9
BP 257
EP 266
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 826IY
UT WOS:000295349000005
PM 25879266
DA 2026-07-24
ER

PT J
AU Bobkiewicz, A
   Francuzik, W
   Martinkosky, A
   Borejsza-Wysocki, M
   Ledwosinski, W
   Szmyt, K
   Banasiewicz, T
   Krokowicz, L
AF Bobkiewicz, Adam
   Francuzik, Wojciech
   Martinkosky, Amy
   Borejsza-Wysocki, Maciej
   Ledwosinski, Witold
   Szmyt, Krzysztof
   Banasiewicz, Tomasz
   Krokowicz, Lukasz
TI Negative Pressure Level and Effects on Bacterial Growth Kinetics in an
   in vitro Wound Model
SO POLISH JOURNAL OF MICROBIOLOGY
LA English
DT Article
DE negative pressure wound therapy; bacterial growth; wound healing;
   bioburden
ID VACUUM-ASSISTED CLOSURE; THERAPY; RECOMMENDATIONS
AB Negative Pressure Wound Therapy (NPWT) has been widely adopted in wound healing strategies due to its multimodal mechanism of action. While NPWT's positive impression on wound healing is well-established, its effect on bacterial load reduction remains equivocal. This study investigates NPWT's efficacy in reducing bioburden using an in vitro porcine skin model, focusing on the impact of Staphylococcus aureus and Staphylococcus epidermidis. Custom-made negative pressure chambers were employed to apply varying negative pressures. Porcine skin was cut into 5 x 5 cm squares and three standardized wounds of 6 mm each were created using a biopsy punch. Then, wounds were infected with S. aureus and S. epidermidis bacterial suspensions diluted 1:10,000 to obtain a final concentration of 1.5 x 10(4) CFU/ml and were placed in negative pressure chambers. After incubation, bacterial counts were expressed as colony-forming units (CFU) per ml. For S. aureus at 120 hours, the median CFU, mean area per colony, and total growth area were notably lower at -80 mmHg when compared to -250 mmHg and -50 mmHg, suggesting an optimal negative pressure for the pressure-dependent inhibition of the bacterial proliferation. While analyzing S. epidermidis at 120 hours, the response to the negative pressure was similar but less clear, with the minor CFU at -100 mmHg. The influence of intermittent negative pressure on the S. epidermidis growth showed notably lower median CFU with the interval therapy every hour compared to the S. aureus control group. This study contributes valuable insights into NPWT's influence on the bacterial load, emphasizing the need for further research to reformulate its role in managing contaminated wounds.
C1 [Bobkiewicz, Adam; Martinkosky, Amy; Borejsza-Wysocki, Maciej; Ledwosinski, Witold; Szmyt, Krzysztof; Banasiewicz, Tomasz; Krokowicz, Lukasz] Poznan Univ Med Sci, Dept Gen Endocrinol Surg & Gastroenterol Oncol, Poznan, Poland.
   [Francuzik, Wojciech] Charite Univ Med Berlin, Dept Dermatol Venerol & Allergol, Berlin, Germany.
C3 Poznan University of Medical Sciences; Free University of Berlin;
   Humboldt University of Berlin; Charite Universitatsmedizin Berlin
RP Krokowicz, L (通讯作者)，Poznan Univ Med Sci, Dept Gen Endocrinol Surg & Gastroenterol Oncol, Poznan, Poland.
EM lkrokowicz@gmail.com
RI Francuzik, Wojciech/H-6773-2019
OI Francuzik, Wojciech/0000-0001-5361-9876
CR Anagnostakos K, 2012, J WOUND CARE, V21, P333, DOI 10.12968/jowc.2012.21.7.333
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NR 32
TC 7
Z9 7
U1 0
U2 3
PU POLSKIE TOWARZYSTWO MIKROBIOLOGOW-POLISH SOCIETY OF MICROBIOLOGISTS
PI WARSAW
PA BANACHA 1 B, WARSAW, POLAND
SN 1733-1331
EI 2544-4646
J9 POL J MICROBIOL
JI Pol. J. Microbiol.
PD JUN 1
PY 2024
VL 73
IS 2
BP 199
EP 206
DI 10.33073/pjm-2024-018
PG 8
WC Microbiology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Microbiology
GA WA6N2
UT WOS:001252187800012
PM 38905277
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Wu, MF
   Liu, QX
   Yu, Z
   Karvar, M
   Aoki, S
   Hamaguchi, R
   Ma, CH
   Orgill, DP
   Panayi, AC
AF Wu, Mengfan
   Liu, Qinxin
   Yu, Zhen
   Karvar, Mehran
   Aoki, Shimpo
   Hamaguchi, Ryoko
   Ma, Chenhao
   Orgill, Dennis P.
   Panayi, Adriana C.
TI Negative-Pressure Wound Therapy Induces Lymphangiogenesis in Murine
   Diabetic Wound Healing
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; LYMPHATIC-SYSTEM; FOOT ULCERS; MAST-CELLS;
   INFLAMMATION; MECHANISMS; RESOLUTION; PROTEASES; DRAINAGE
AB Background: Decreased lymphangiogenesis contributes to impaired diabetic wound healing. Although negative-pressure wound therapy (NPWT) has been shown to be effective in the treatment of recalcitrant wounds, its impact on lymphangiogenesis remains to be elucidated. In this study, the authors investigate the mechanisms of lymphangiogenesis following NPWT treatment of diabetic murine wound healing.
   Methods: Full-thickness dorsal skin wounds (1 x 1 cm(2)) were excised on 30 db/ db mice. The mice were either treated with occlusive covering (control group, n = 15), or received a 7-day treatment of continuous NPWT at -125 mmHg (NPWT group, n = 15). The wounds were photographed on days 0, 7, 10, 14, 21, and 28. Wound tissue was harvested on days 10, 14, 21, and 28 for quantitative analysis. Functional analysis of lymphatic drainage was performed on days 14 and 28 with Evans blue dye tracing.
   Results: Lymphatic density and diameter, as visualized through podoplanin probing, was significantly higher in the NPWT group compared to the control group (P < 0.001). NPWT up-regulated the expression of lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1) at the protein level (P = 0.04), and significant differences were noted in lymphatic density as assessed by LYVE-1 staining (P = 0.001). Leukocyte infiltration was significantly higher in the NPWT group (P = 0.01). A higher speed of wound closure (P < 0.0001) and greater wound bed thickness (P < 0.0001) were noted in the NPWT group compared to the control group.
   Conclusions: NPWT increased the lymphatic vessel density and diameter with LYVE-1 up-regulation. NPWT therefore plays a positive role in lymphangiogenesis in diabetic wound healing.
C1 [Wu, Mengfan; Liu, Qinxin; Karvar, Mehran; Aoki, Shimpo; Hamaguchi, Ryoko; Ma, Chenhao; Orgill, Dennis P.; Panayi, Adriana C.] Brigham & Womens Hosp, Dept Surg, Div Plast Surg, Boston, MA USA.
   [Wu, Mengfan; Liu, Qinxin; Karvar, Mehran; Aoki, Shimpo; Hamaguchi, Ryoko; Ma, Chenhao; Orgill, Dennis P.; Panayi, Adriana C.] Harvard Med Sch, Boston, MA 02115 USA.
   [Wu, Mengfan] Peking Univ Shenzhen Hosp, Dept Plast Surg, Shenzhen, Peoples R China.
   [Liu, Qinxin] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Traumat Surg, Wuhan, Peoples R China.
   [Yu, Zhen] Harvard Med Sch, Massachusetts Eye & Ear Infirm, Ophthalmol Dept, Angiogenesis Lab, Boston, MA 02115 USA.
   [Yu, Zhen] Jinan Univ, Shenzhen Eye Hosp, Shenzhen Key Ophthalm Lab, Guangzhou, Peoples R China.
   [Ma, Chenhao] Tsinghua Univ, Plast Surg Hosp, Peking Union Med Coll, Dept Auricular Reconstruct, Beijing, Peoples R China.
   [Ma, Chenhao] Chinese Acad Med Sci, Beijing, Peoples R China.
   [Panayi, Adriana C.] Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard University; Harvard Medical School; Peking
   University; Huazhong University of Science & Technology; Harvard
   University; Harvard University Medical Affiliates; Massachusetts Eye &
   Ear Infirmary; Harvard Medical School; Shenzhen Eye Hospital; Jinan
   University; Chinese Academy of Medical Sciences - Peking Union Medical
   College; Peking Union Medical College; Tsinghua University; Chinese
   Academy of Medical Sciences - Peking Union Medical College; Harvard
   University; Harvard University Medical Affiliates; Brigham & Women's
   Hospital; Harvard Medical School
RP Panayi, AC (通讯作者)，Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
EM apanayi@bwh.harvard.edu
RI Orgill, Dennis/H-7596-2019; Panayi, Adriana/HHT-0513-2022; Ma,
   Chenhao/AFN-9286-2022
OI Wu, Mengfan/0000-0003-2646-3372; Panayi, Adriana/0000-0003-4053-9855;
   Yu, Zhen/0000-0003-3456-3584; 
FU Gillian Reny Stepping Strong Center for Trauma Innovation and Kinetic
   Concepts, Inc.
FX This work was funded by The Gillian Reny Stepping Strong Center for
   Trauma Innovation and Kinetic Concepts, Inc. The authors express their
   gratitude to Diane Bielenberg, PhD, for expert guidance in developing
   the lymphatic-specific immunohistochemical techniques, to George Murphy,
   MD, for generously allowing the authors' use of the laboratory facility
   and equipment in the optimization process, and to Diana Wang, MD, for
   assistance in advising the optimization.
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NR 56
TC 15
Z9 18
U1 2
U2 13
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD APR
PY 2023
VL 151
IS 4
BP 779
EP 790
DI 10.1097/PRS.0000000000009997
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA D7CH7
UT WOS:000970264400042
PM 36729939
DA 2026-07-24
ER

PT J
AU Vaidhya, N
   Panchal, A
   Anchalia, MM
AF Vaidhya, Nikunj
   Panchal, Arpit
   Anchalia, M. M.
TI A New Cost-effective Method of NPWT in Diabetic Foot Wound
SO INDIAN JOURNAL OF SURGERY
LA English
DT Article
DE Negative-pressure wound therapy; Dressing; Improvised; Cost-effective
ID VACUUM-ASSISTED-CLOSURE; THERAPY
AB Diabetic foot wounds present a great challenge to surgeons. They are difficult to heal and are a significant risk factor for non-traumatic foot amputation besides being a huge financial burden. NPWT systems commercially available (VAC (TM) system, KCI Inc., USA) are costly precluding widespread use. To determine whether negative-pressure wound therapy (NPWT) would afford quicker wound recovery as compared to saline-moistened gauze in the treatment of diabetic foot wounds. Sixty patients were randomized into either the experimental NPWT group or conventional dressing group (control). All patients were given medical therapy for diabetes and antibiotics given according to culture and sensitivity patterns. All foot ulcers were surgically debrided prior to initiation of NPWT or conventional treatment. In the NPWT group, dressings were changed every 48-72 h. In the control group, conventional dressings were applied at the time of surgical debridement and changed twice a day thereafter. End point of study was when wound was ready for either skin grafting or secondary suturing. End point was achieved in the NPWT group in 17.2(SD +/- 3.55) days, compared to 34.9 (SD +/- 5.96) days in the control group (p<0.001). Number of dressing applied were 7.46(SD +/- 2.25) in NPWT group versus 69.8(SD +/- 11.93) in conventional dressing group (p<0.001). Ninety percent cases were successfully treated in NPWT Group as compared to 76.6 % in conventional group. Rate of healing of ulcer is faster in NPWT group as compared to conventional group. Economically modified NPWT is more cost-effective to the patients in our setup.
C1 [Vaidhya, Nikunj; Anchalia, M. M.] Civil Hosp, BJ Med Coll, Dept Gen Surg, Ahmadabad, Gujarat, India.
   [Panchal, Arpit] Govt Med Coll, Dept Gen Surg, Vadodara, India.
C3 B. J. Medical College & Civil Hospital, Ahmedabad
RP Vaidhya, N (通讯作者)，Civil Hosp, BJ Med Coll, Dept Gen Surg, Ahmadabad, Gujarat, India.
EM nikunjvaidhya@gmail.com
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NR 18
TC 32
Z9 37
U1 0
U2 25
PU SPRINGER INDIA
PI NEW DELHI
PA 7TH FLOOR, VIJAYA BUILDING, 17, BARAKHAMBA ROAD, NEW DELHI, 110 001,
   INDIA
SN 0972-2068
EI 0973-9793
J9 INDIAN J SURG
JI Indian J. Surg
PD DEC
PY 2015
VL 77
SU 2
BP S525
EP S529
DI 10.1007/s12262-013-0907-3
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DB5CP
UT WOS:000368531700067
PM 26730058
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Powell, ET
AF Powell, Ehaa T.
TI The Role of Negative Pressure Wound Therapy With Reticulated Open Cell
   Foam in the Treatment of War Wounds
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE NPWT/ROCF; aeromedical; VAC; VAC Therapy
ID VACUUM-ASSISTED CLOSURE; SOFT-TISSUE INJURIES; EXPERIENCE
AB The treatment of war wounds poses many unique challenges to all healthcare providers (surgeons, flight medics, nurses, etc.), whether they arc located at the far forward trauma hospitals located in or near areas of conflict, at regional hospitals Such as Landstuhl Medical Center in Germany, or the larger military hospitals in the United States. These complex wounds often involve massive loss of soft tissue and bone, arc contaminated, and are unlike most injuries seen at civilian hospitals. Treatment guidelines, or doctrine, Lire the result of lessons learned in conflicts over the past few centuries dating back to early 19th century Europe through the Vietnam and recent Persian Gulf war. Advances in surgical and medical treatment have resulted from the complex challenges presented to the war trauma surgeon. More than I million patients have been treated for chronic pressure ulcers, abdominal wounds, diabetic ulcers. and acute civilian trauma wounds with negative pressure wound therapy with reticulated open cell foam (NPWT/ROCF) as delivered by VA.C.(R) Therapy (KCI, San Antonio. TX) for over the past decade. However, the use of NPWT/ROCF for the care of war Wounds at battlefield trauma hospitals and/or in the aeromedical evacuation transport system aboard aircraft is a new application of this wound treatment not yet accepted as doctrine. Investigational studies are ongoing to Study the safety and efficacy of the treatment of battlefield wounds with NPWT/ROCF both for those national citizens treated at the trauma hospitals in Iraq and Afghanistan and for those Wounded American and coalition patients who are transported through the aeromedical transport system to medical centers in the United States.
C1 [Powell, Ehaa T.] 3rd Med Grp, Elmendorf AFB, AK USA.
C3 United States Department of Defense; United States Air Force
RP Powell, ET (通讯作者)，Alaska Reg Hosp, 2751 DeBarr Rd,Suite 310, Anchorage, AK 99508 USA.
EM etpowell@gci.net
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   Bagg Mark R, 2006, J Am Acad Orthop Surg, V14, pS7
   BURRIS DG, 2004, EMERGENCY WAR SURG 3
   Covey Dana C, 2008, Instr Course Lect, V57, P65
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NR 15
TC 28
Z9 36
U1 0
U2 8
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0890-5339
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD NOV-DEC
PY 2008
VL 22
IS 10
SU S
BP S138
EP S141
DI 10.1097/BOT.0b013e318188e27d
PG 4
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 371GP
UT WOS:000260820100004
PM 19034160
DA 2026-07-24
ER

PT J
AU Nolff, MC
   Meyer-Lindenberg, A
AF Nolff, Mirja C.
   Meyer-Lindenberg, Andrea
TI Negative pressure wound therapy augmented full-thickness free skin
   grafting in the cat: outcome in 10 grafts transferred to six cats
SO JOURNAL OF FELINE MEDICINE AND SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE
AB Objectives The aim of this clinical evaluation was to describe the technique and outcomes of negative pressure wound therapy (NPWT) augmented skin grafting in cats.
   Methods Cats with soft tissue and skin defects (n = 6) underwent open wound management. Wounds were initially covered using a NPWT system that was changed to polyurethane foam dressing once infection was controlled and granulation started. Final closure was achieved after establishment of a healthy, fully granulated wound bed by grafting of free full-thickness skin from the lateral abdominal wall. The freshly grafted skin was then treated with an NPWT dressing at a pressure of -125 mmHg for 3 days, with dressing changes performed daily. Percentage graft take, complications, wound bioburden and cosmetic outcome were recorded.
   Results The mean duration of open wound management was 21.4 days (range 3.0-45.0 days), with a mean duration of NPWT of 8.0 days (range 3.0-14.0 days). Five cats received a single graft, while one cat had five grafts transferred to the right hindlimb. In 7/10 grafts, graft take was 100%, in two grafts take was 95% and in one graft take was 80% (mean take rate 97%). Therapy was well tolerated in all patients. The grafted site displayed normal hair regrowth in four cats, sparse hair regrowth in one and no hair growth at all in one patient. Skin sensation was normal in all grafted patients.
   Conclusions and relevance Skin graft augmentation using NPWT in cats is a feasible option that allows graft fixation, even in anatomically demanding areas. Graft take rate reported here is slightly higher than documented in previous reports.
C1 [Nolff, Mirja C.; Meyer-Lindenberg, Andrea] Univ Munich, Clin Small Anim Surg & Reprod, D-80539 Munich, Germany.
C3 University of Munich
RP Nolff, MC (通讯作者)，Univ Munich, Clin Small Anim Surg & Reprod, Vet Str 13, D-80539 Munich, Germany.
EM m.nolff@lmu.de
RI Nolff, Mirja/W-6756-2019; Meyer-Lindenberg, Andrea/H-1076-2011
OI Nolff, Mirja/0000-0001-9317-7769; Meyer-Lindenberg,
   Andrea/0000-0001-6137-3773
CR [Anonymous], BR J PLAST SURG
   [Anonymous], J AM VET MED ASS
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NR 17
TC 16
Z9 21
U1 0
U2 20
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1098-612X
EI 1532-2750
J9 J FELINE MED SURG
JI J. Feline Med. Surg.
PD DEC
PY 2015
VL 17
IS 12
BP 1041
EP 1048
DI 10.1177/1098612X15569893
PG 8
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA CX5FH
UT WOS:000365727000010
PM 25656341
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Lindstedt, S
   Ingemansson, R
   Malmsjö, M
AF Lindstedt, Sandra
   Ingemansson, Richard
   Malmsjo, Malin
TI A rigid barrier between the heart and sternum protects the heart and
   lungs against rupture during negative pressure wound therapy
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MEDIAN STERNOTOMY INCISION; POSTSTERNOTOMY
   MEDIASTINITIS; AGGRESSIVE MANAGEMENT; EARLY INTERVENTION;
   CARDIAC-SURGERY; EXPERIENCE; INFECTION; GAUZE
AB Objectives: Right ventricular heart rupture is a devastating complication associated with negative pressure wound therapy (NPWT) in cardiac surgery. The use of a rigid barrier has been suggested to offer protection against this lethal complication, by preventing the heart from being drawn up and damaged by the sharp edges of the sternum. The aim of the present study was to investigate whether a rigid barrier protects the heart and lungs against injury during NPWT.
   Methods: Sixteen pigs underwent median sternotomy followed by NPWT at -120 mmHg for 24 hours, in the absence (eight pigs) or presence (eight pigs) of a rigid plastic disc between the heart and the sternal edges. The macroscopic appearance of the heart and lungs was inspected after 12 and 24 hours of NPWT.
   Results: After 24 hours of NPWT at -120 mmHg the area of epicardial petechial bleeding was 11.90 +/- 1.10 cm(2) when no protective disc was used, and 1.15 +/- 0.19 cm(2) when using the disc (p < 0.001). Heart rupture was observed in three of the eight animals treated with NPWT without the disc. Lung rupture was observed in two of the animals, and lung contusion and emphysema were seen in all animals treated with NPWT without the rigid disc. No injury to the heart or lungs was observed in the group of animals treated with NPWT using the rigid disc.
   Conclusion: Inserting a rigid barrier between the heart and the sternum edges offers protection against heart rupture and lung injury during NPWT.
C1 [Lindstedt, Sandra] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
   Skane Univ Hosp, Lund, Sweden.
C3 Lund University; Lund University; Skane University Hospital
RP Lindstedt, S (通讯作者)，Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
EM sandra.lindstedt@skane.se
RI ; Lindstedt, Sandra/AEM-2892-2022
OI Maljö, Malin/0000-0001-9849-9599; Lindstedt, Sandra/0000-0003-4484-6473;
   Ingemansson, Richard/0000-0001-7623-8953
FU Swedish Medical Research Council, Lund University Faculty of Medicine;
   Swedish Government; Swedish Medical Association; Royal Physiographic
   Society in Lund; Ake Wiberg Foundation; Anders Otto Sward Foundation;
   Ulrika Eklund Foundation; Magn Bergvall Foundation; Crafoord Foundation;
   Anna-Lisa and Sven-Erik Nilsson Foundation; Jeansson Foundation; Swedish
   Heart-Lung Foundation; Anna and Edvin Berger's Foundation; Marta
   Lundqvist Foundation; Lars Hierta's Memorial Foundation
FX This study was supported by the Swedish Medical Research Council, Lund
   University Faculty of Medicine, the Swedish Government Grant for
   Clinical Research, Lund University Hospital Research Grants, the Swedish
   Medical Association, the Royal Physiographic Society in Lund, the Ake
   Wiberg Foundation, the Anders Otto Sward Foundation/Ulrika Eklund
   Foundation, the Magn Bergvall Foundation, the Crafoord Foundation, the
   Anna-Lisa and Sven-Erik Nilsson Foundation, the Jeansson Foundation, the
   Swedish Heart-Lung Foundation, Anna and Edvin Berger's Foundation, the
   Marta Lundqvist Foundation, and Lars Hierta's Memorial Foundation.
CR Bapat V, 2008, J CARDIAC SURG, V23, P227, DOI 10.1111/j.1540-8191.2008.00595.x
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NR 19
TC 5
Z9 6
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD JUL 8
PY 2011
VL 6
AR 90
DI 10.1186/1749-8090-6-90
PG 5
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 796PT
UT WOS:000293064800001
PM 21740574
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Armstrong, DG
   Lavery, LA
AF Armstrong, DG
   Lavery, LA
CA Diabet Foot Study Consortium
TI Negative pressure wound therapy after partial diabetic foot amputation:
   a multicentre, randomised controlled trial
SO LANCET
LA English
DT Article
ID MANAGEMENT; ULCERS; RISK; DERMAGRAFT
AB Background Diabetic foot wounds, particularly those secondary to amputation, are very complex and difficult to treat. We investigated whether negative pressure wound therapy (NPWT) improves the proportion and rate of wound healing after partial foot amputation in patients with diabetes.
   Methods We enrolled 162 patients into a 16-week, 18-centre, randomised clinical trial in the USA. Inclusion criteria consisted of partial foot amputation wounds up to the transmetatarsal level and evidence of adequate perfusion. Patients who were randomly assigned to NPWT (n=77) received treatment with dressing changes every 48 h. Control patients (n=85) received standard moist wound care according to consensus guidelines. NPWT was delivered through the Vacuum Assisted Closure (VAC) Therapy System. Wounds were treated until healing or completion of the 112-day period of active treatment. Analysis was by intention to treat. This study has been registered with ClinicalTrials.gov, number NCT00224796.
   Findings More patients healed in the NPWT group than in the control group (43 [56%] vs 33 [39%], p=0.040). The rate of wound healing, based on the time to complete closure, was faster in the NPWT group than in controls (p=0.005). The rate of granulation tissue formation, based on the time to 76-100% formation in the wound bed, was faster in the NPWT group than in controls (p=0.002). The frequency and severity of adverse events (of which the most common was wound infection) were similar in both treatment groups.
   Interpretation NPWT delivered by the VAC Therapy System seems to be a safe and effective treatment for complex diabetic foot wounds, and could lead to a higher proportion of healed wounds, faster healing rates, and potentially fewer re-amputations than standard care.
C1 Rosalind Franklin Univ Med & Sci, Scholls Ctr Lower Extrem Ambulatory Res, Chicago, IL 60064 USA.
   Texas A&M Univ, Hlth Sci Ctr, Coll Med, Scott & White Hosp,Dept Surg, Temple, TX USA.
C3 Chicago Medical School; Rosalind Franklin University of Medicine &
   Science; Texas A&M University System; Texas A&M University College
   Station; Texas A&M Health Science Center
RP Armstrong, DG (通讯作者)，Rosalind Franklin Univ Med & Sci, Scholls Ctr Lower Extrem Ambulatory Res, Chicago, IL 60064 USA.
EM Armstrong@usa.net
OI Lavery, Lawrence/0000-0002-7920-9952
CR [Anonymous], 2004, WOUNDS, p3S
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NR 43
TC 700
Z9 830
U1 4
U2 117
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0140-6736
EI 1474-547X
J9 LANCET
JI Lancet
PD NOV 12
PY 2005
VL 366
IS 9498
BP 1704
EP 1710
DI 10.1016/S0140-6736(05)67695-7
PG 7
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 983BP
UT WOS:000233206400025
PM 16291063
DA 2026-07-24
ER

PT J
AU Khoo, MJW
   Ooi, ASH
AF Khoo, Mark Junn Wei
   Ooi, Adrian Seng Huan
TI Management of postreconstructive head and neck salivary fistulae: A
   review of current practices
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Review
DE Salivary fistula; Enterocutaneous fistula; Pharyngocutaneous fistula;
   Orocutaneous fistula; Reconstructive surgery; Negative pressure wound
   therapy
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; FREE TISSUE TRANSFER;
   PHARYNGOCUTANEOUS-FISTULA; LARYNGECTOMY DEFECTS; MICROSURGICAL HEAD;
   RECONSTRUCTION; COMPLICATIONS; METAANALYSIS; DESIGN
AB Background: Salivary fistulas are common complications after reconstructive head and neck surgery with significant morbidity. Yet, there are no established guidelines for their management.
   Method: A comprehensive search of PubMed was performed from 01/01/2000 to 06/31/2019 to evaluate all treatment options in postreconstructive head and neck fistulas.
   Results: Nineteen articles with 132 patients were included. Thirty-nine of 132(30%) patients were treated with conventional wound care. All fistulas closed after 51.6 +/- 54.0 days with no refistulations. Thirty-eight of 132(29%) patients were treated with negative pressure wound therapy (NPWT). Thirty-eight of 40(95%) fistula closed after 14.7 +/- 12.0 days with no refistulations. The reduced healing time was statistically significant as compared to patients on conventional wound care (p < 0.001). Fifty-three of 132(40%) patients received surgical management. Fortyfour of 53(83%) patients had complete fistula closure without postoperative complications. A pedicled flap was used in 60% of cases (n = 32).
   Conclusion: Most salivary fistulas close with conservative management. NPWT potentially shortens fistula healing time while it achieves similar closure rates as conventional wound care. In the absence of contraindications, NPWT should be trialed on all salivary fistulas. Surgical management should be reserved for large, chronic, high-risk fistulas or those not responding to a trial of conservative treatment. Secondary reconstruction should be kept as simple as possible. (C) 2021 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Khoo, Mark Junn Wei] Natl Univ Hlth Syst, Yong Loo Lin Sch Med, Singapore, Singapore.
   [Ooi, Adrian Seng Huan] Mt Elizabeth Med Ctr, Polaris Plast & Reconstruct Surg, 3 Mt Elizabeth,08-05, Singapore 288510, Singapore.
C3 National University of Singapore; Mount Elizabeth Medical Centre
RP Ooi, ASH (通讯作者)，Mt Elizabeth Med Ctr, Polaris Plast & Reconstruct Surg, 3 Mt Elizabeth,08-05, Singapore 288510, Singapore.
EM adrian.ooi.s.h@singhealth.com.sg
RI Ooi, Adrian/AAJ-8480-2021
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NR 45
TC 25
Z9 31
U1 0
U2 3
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD SEP
PY 2021
VL 74
IS 9
BP 2120
EP 2132
DI 10.1016/j.bjps.2020.12.096
EA SEP 2021
PG 13
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WK5AA
UT WOS:000709736900018
PM 33551359
DA 2026-07-24
ER

PT J
AU Ferreira, APP
   Vide, SS
   Fernandes, TDF
   Coelho, PMBD
   Camacho, OF
AF Pinto Ferreira, Antonio Pedro
   Vide, Sergio Santos
   Fonseca Fernandes, Tiago David
   Barata de Silva Coelho, Pedro Miguel
   Camacho, Oscar Ferraz
TI Hyperbaric oxygen therapy as an adjuvant to source control in
   necrotizing soft tissue infections
SO UNDERSEA AND HYPERBARIC MEDICINE
LA English
DT Article
DE infectious diseases; necrotizing infections; gas gangrene; hyperbaric
   oxygen therapy; negative-pressure wound therapy; debridement
ID FASCIITIS REDUCES MORTALITY; VACUUM-ASSISTED CLOSURE; DIAGNOSIS;
   MANAGEMENT; SURVIVAL; SKIN
AB Introduction: Necrotizing soft tissue infections (NSTI) are rare but potentially lethal disorders, and adequate management is time-and resource-demanding. This study aims to assess whether variations in the treatment modalities - surgery, hyperbaric oxygen (HBO2) therapy and negative pressure wound therapy - had an impact on the length to definitive source control in NSTI patients who underwent HBO2.
   Methods: This is a retrospective study of all NSTI patients treated with hyperbaric oxygen therapy between March 2007 and May 2015 at Unidade Local de Saude de Matosinhos (ULSM) Hyperbaric Unit. A multiple linear regression model was used to assess the impact of different treatment modalities in the post-diagnosis time until source control.
   Results: 58 patients were included; overall mortality was 13.8%. Mean time until source control was 10.4 days (+/- 5.4). All patients were under empiric and broad-spectrum antibiotics on the day of diagnosis. Patients underwent an average of 0.62 (+/- 0.29) surgical interventions and 1.06 (+/- 0.52) HBO2 sessions per day. The regression model (R-2=0.86) showed that after adjusting for other covariates, doubling the number of HBO2 sessions per day shortened source control by five days (beta=-5.25; 95% CI -6.49 to -4.01), and for each day that HBO2 was delayed, source control was achieved one day later (beta = 1.03; 95% CI 0.82 to 1.24).
   Conclusion: More intensive HBO2 protocols with earlier and more frequent sessions shorten the time until definitive source control in necrotizing soft tissue infections, potentially lowering the impact of systemic effects of infection and complications associated with organ dysfunction.
C1 [Pinto Ferreira, Antonio Pedro; Fonseca Fernandes, Tiago David] Dept Anesthesiol, Matosinhos Local Hlth Unit, Hyperbar Med Unit, Matosinhos, Portugal.
   [Vide, Sergio Santos; Camacho, Oscar Ferraz] Dept Anesthesiol, Matosinhos Local Hlth Unit, Matosinhos, Portugal.
   [Barata de Silva Coelho, Pedro Miguel] Univ Fernando Pessoa, Oporto, Portugal.
C3 Universidade Fernando Pessoa
RP Ferreira, APP (通讯作者)，Dept Anesthesiol, Matosinhos Local Hlth Unit, Hyperbar Med Unit, Matosinhos, Portugal.
EM antonio.pedroferreira@ulsm.min-saude.pt
RI ; Vide, Sérgio/AAN-8341-2020
OI Ferreira, António Peo/0000-0001-7190-4742; Vide,
   Sérgio/0000-0002-8185-2250
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NR 36
TC 3
Z9 5
U1 0
U2 9
PU UNDERSEA & HYPERBARIC MEDICAL SOC INC
PI DURHAM
PA 21 WEST COLONY PLACE, STE 280, DURHAM, NC 27705 USA
SN 1066-2936
J9 UNDERSEA HYPERBAR M
JI Undersea Hyperb. Med.
PD NOV-DEC
PY 2017
VL 44
IS 6
BP 535
EP 542
DI 10.22462/11.12.2017.4
PG 8
WC Marine & Freshwater Biology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Marine & Freshwater Biology; Research & Experimental Medicine
GA FW2GE
UT WOS:000425120200004
PM 29281190
DA 2026-07-24
ER

PT J
AU Kim, SW
   Youn, DG
   Hwang, KT
   Kim, JT
   Kim, YH
AF Kim, Sang Wha
   Youn, Dong Geun
   Hwang, Kyu Tae
   Kim, Jeong Tae
   Kim, Youn Hwan
TI RECONSTRUCTION OF SEVERELY INFECTED GLUTEAL OSTEORADIONECROSIS USING
   NEGATIVE-PRESSURE WOUND THERAPY AND LATISSIMUS DORSI MUSCULOCUTANEOUS
   FLAPS
SO MICROSURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; BACTERIAL INOCULATION; PERFORATOR FLAP; NORMAL
   TISSUE; SUPERIOR; SALVAGE; MANAGEMENT; RADIATION; DEFECT
AB Radiotherapy is mandatory for aggressive cancer treatment. Unfortunately, the high-energy radiation used can lead to severe osteoradionecrosis. Radical debridement of devitalized bone and soft tissue coupled with reconstruction using well-vascularized tissues is the accepted treatment for this condition. However, osteoradionecrosis cannot be controlled easily or rapidly. The aim of this study was to present the results of the use of serial negative-pressure wound therapy (NPWT) in combination with a latissimus dorsi myocutaneous flap for treatment of gluteal osteoradionecrosis in a consecutive series of patients. Between January 2003 and December 2012, nine patients underwent reconstruction using serial NPWT and latissimus dorsi myocutaneous flaps. We applied negative-pressure dressings for at least 8 weeks. Final reconstruction was performed after the infection was controlled. The superior gluteal artery and vein were used as recipient vessels in all the cases. The mean interval between operation and radiation therapy was 28.3 +/- 8.3 years, and the mean number of debridement performed was 6.3 +/- 1. NPWT dressings were applied for 8-12 weeks (mean, 9.3 +/- 2 weeks). The defects ranged in size from 14 x 8 cm to 18 x 15 cm. The flap size ranged from 15 x 10 cm to 18 x 15 cm. All flaps survived uneventfully except in one patient who experienced chronic seroma and wound dehiscence. There were no recurrences of osteomyelitis during the follow-up periods (mean, 14 +/- 6.1 months). Based on the results obtained from this consecutive series of patients, we suggest that this methodology may provide an alternative approach for the treatment of severe osteoradionecrosis of the gluteal region. (C) 2015 Wiley Periodicals, Inc.
C1 [Kim, Sang Wha] Catholic Univ Korea, Dept Plast & Reconstruct Surg, Seoul, South Korea.
   [Youn, Dong Geun; Kim, Jeong Tae; Kim, Youn Hwan] Hanyang Univ, Coll Med, Dept Plast & Reconstruct Surg, Seoul 133791, South Korea.
   [Hwang, Kyu Tae] Hanyang Univ, Dept Orthoped Surg, Coll Med, Seoul 133791, South Korea.
C3 Catholic University of Korea; Hanyang University; Hanyang University
RP Kim, YH (通讯作者)，Hanyang Univ, Sch Med, Dept Plast & Reconstruct Surg, 17 Haengdang Dong, Seoul 133792, South Korea.
EM younhwank@daum.net
RI Hwang, Kyu/R-7249-2016
OI Kim, Sang Wha/0000-0003-0430-3458
FU Hanyang University [HY-2013]
FX Grant sponsor: Hanyang University; Grant number: HY-2013.
CR Annane D, 2004, J CLIN ONCOL, V22, P4893, DOI 10.1200/JCO.2004.09.006
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NR 30
TC 8
Z9 9
U1 0
U2 9
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0738-1085
EI 1098-2752
J9 MICROSURG
JI Microsurgery
PD JAN
PY 2016
VL 36
IS 1
BP 29
EP 36
DI 10.1002/micr.22370
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DF6SM
UT WOS:000371486700003
PM 25641653
OA Bronze
DA 2026-07-24
ER

PT J
AU Lok, E
   Oe, T
   Ng, S
AF Lok, Evania
   Oe, Timothy
   Ng, Sally
TI Lower Extremity Traumatic Wound Management: Relative Significance of
   Negative Pressure Wound Therapy in the Orthopedic Setting
SO ADVANCES IN WOUND CARE
LA English
DT Article
DE orthopedics; NPWT; NPWTi-d; open fracture; lower limb trauma wound
ID VACUUM-ASSISTED CLOSURE; THICKNESS SKIN-GRAFTS; SEVERE OPEN FRACTURES;
   CLINICAL-EVALUATION; GRANULATION-TISSUE; GAUZE; INCISION; FLAPS; CARE;
   RECONSTRUCTION
AB Significance: Lower extremity traumatic wounds are associated with numerous perioperative challenges. Their etiologies determine the characteristics and extent of the injury. The timing of subsequent surgical intervention and wound healing optimization after lower extremity trauma are integral to successful perioperative lower extremity wound management.Recent Advances: Managing trauma to the lower extremities uses a multidisciplinary surgical approach. The objective of this review is to summarize lower limb trauma assessment, advancements in lower extremity trauma management, and the clinical applications of advanced wound care in lower limb traumatic wounds. The advent of lower limb reconstruction and the development of advanced wound care modalities have helped to improve the management of these complex injuries.Critical Issues: The extensive involvement of bone, soft tissues, nerves, and blood vessels of severe lower extremity trauma wounds presents a challenge for clinicians in both the acute care setting and during patient rehabilitation. If not properly managed, these injuries may be subject to a decline in limb function and may possibly result in limb loss. To reveal developing limb-threatening conditions, serial examinations should be performed.Future Directions: The majority of lower limb traumatic wound will benefit from the perioperative administration of an appropriate negative pressure wound therapy (NPWT)-based system, which can help to promote granulation tissue and remove wound exudate before definitive closure and/or reconstruction. NPWT should be included as an important adjunct in the surgical management of lower limb traumatic wounds.
C1 [Lok, Evania; Oe, Timothy; Ng, Sally] Austin Hlth, Dept Plast & Reconstruct Surg, 45 Studley Rd, Melbourne 3084, Australia.
   [Ng, Sally] Univ Melbourne, Dept Surg Austin Precinct, Melbourne, Australia.
C3 Florey Institute of Neuroscience & Mental Health; Howard Florey
   Institute Affiliates; University of Melbourne
RP Ng, S (通讯作者)，Austin Hlth, Dept Plast & Reconstruct Surg, 45 Studley Rd, Melbourne 3084, Australia.; Ng, S (通讯作者)，Univ Melbourne, Dept Surg Austin Precinct, Melbourne, Australia.
EM sally.ng@austin.org.au
RI Ng, Sally/AAU-2796-2021
OI Ng, Sally/0000-0001-7332-627X
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NR 105
TC 4
Z9 4
U1 0
U2 3
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD JUL 1
PY 2025
VL 14
IS 7
BP 327
EP 343
DI 10.1089/wound.2023.0133
EA AUG 2024
PG 17
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 4LZ2B
UT WOS:001295581400001
PM 39001834
OA hybrid
DA 2026-07-24
ER

PT J
AU Rys, P
   Borys, S
   Hohendorff, J
   Zapala, A
   Witek, P
   Monica, M
   Frankfurter, C
   Ludwig-Slomczynska, A
   Kiec-Wilk, B
   Malecki, MT
AF Rys, Przemyslaw
   Borys, Sebastian
   Hohendorff, Jerzy
   Zapala, Aleksandra
   Witek, Przemyslaw
   Monica, Magdalena
   Frankfurter, Claudia
   Ludwig-Slomczynska, Agnieszka
   Kiec-Wilk, Beata
   Malecki, Maciej T.
TI NPWT in diabetic foot wounds-a systematic review and meta-analysis of
   observational studies
SO ENDOCRINE
LA English
DT Review
DE Negative-pressure wound therapy; Diabetic foot syndrome; Wound healing
ID VACUUM-ASSISTED CLOSURE; LIMB SALVAGE; THERAPY; ULCERS; MULTICENTER;
   EXPERIENCE; AMPUTATION
AB Purpose Negative-pressure wound therapy (NPWT) is an adjunct modality in diabetic foot ulcerations (DFUs). Randomized controlled trials (RCTs) have shown its advantage over standard approaches; however, data from observational studies remain scarce.We performed a systematic review of observational non-RCTs evaluating NPWT efficacy and safety in patients with DFU. Methods Electronic databases were searched for observational studies involving NPWT. The results of single-arm studies were presented as percentages of patients with the outcome of interest. A meta-analysis of comparative studies provided point estimates of outcomes. Continuous outcomes were reported as either weighted or standardized mean differences and dichotomous data as relative risks (RR). Results The search identified 16 relevant observational studies, 12 single-arm, and 4 comparative, reporting on a total of 18,449 patients with DFU, of whom 1882 were managed with NPWT. In the NPWT-treated patients, ulcers were larger (average size range 6.6-27.9 cm(2)), as compared with controls (<= 3 cm(2)). The pooled results showed healing and major amputation in 51% and 5% of NPWT patients, respectively. The meta-analysis of comparative studies revealed lower risk of major amputation [RR = 0.23 (0.07; 0.80)] in NPWT-treated patients. The pooled results for healing rate and risk of any amputation were inconclusive due to large between-study heterogeneity. Overall, 6 deaths out of 158 patients were reported, none of them related to NPWT. Serious adverse events occurred in 6% of patients on NPWT. Conclusions This systematic review of observational studies provided supportive evidence that NWPT is an efficient and safe adjunct treatment in the management of DFUs.
C1 [Rys, Przemyslaw; Zapala, Aleksandra; Monica, Magdalena] HTA Consulting, Krakow, Poland.
   [Borys, Sebastian; Hohendorff, Jerzy; Witek, Przemyslaw; Kiec-Wilk, Beata; Malecki, Maciej T.] Jagiellonian Univ Med Coll, Dept Metab Dis, Krakow, Poland.
   [Borys, Sebastian; Hohendorff, Jerzy; Witek, Przemyslaw; Kiec-Wilk, Beata; Malecki, Maciej T.] Univ Hosp Krakow, Dept Metab Dis, Krakow, Poland.
   [Frankfurter, Claudia] Univ Toronto, Fac Med, Toronto, ON, Canada.
   [Ludwig-Slomczynska, Agnieszka] Jagiellonian Univ Med Coll, Ctr Med Genom OMICRON, Krakow, Poland.
C3 Jagiellonian University; Collegium Medicum Jagiellonian University;
   Jagiellonian University; Collegium Medicum Jagiellonian University;
   University of Toronto; Jagiellonian University; Collegium Medicum
   Jagiellonian University
RP Malecki, MT (通讯作者)，Jagiellonian Univ Med Coll, Dept Metab Dis, Krakow, Poland.; Malecki, MT (通讯作者)，Univ Hosp Krakow, Dept Metab Dis, Krakow, Poland.
EM maciej.malecki@uj.edu.pl
RI Hohendorff, Jerzy/U-1857-2018; Witek, Przemysław/AGX-0421-2022; Monica,
   Magdalena/JXY-4078-2024
OI Hohendorff, Jerzy/0000-0003-1153-8669; Ludwig-Słomczyńska, Agnieszka
   H/0000-0002-0548-4767; Monica, Magdalena/0000-0001-5089-5349
CR [Anonymous], 2019, 2019 WORKING GROUP W
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NR 34
TC 14
Z9 21
U1 0
U2 16
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1355-008X
EI 1559-0100
J9 ENDOCRINE
JI Endocrine
PD APR
PY 2020
VL 68
IS 1
BP 44
EP 55
DI 10.1007/s12020-019-02164-9
PG 12
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA LE6CS
UT WOS:000526811200006
PM 31919770
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Herskovitz, I
   MacQuhae, FE
   Borda, LJ
   Bhagwandin, S
   Paredes, JA
   Polanco, T
   Lantis, JC
   Kim, PJ
   Phillips, TJ
   Kirsner, RS
AF Herskovitz, Ingrid
   MacQuhae, Flor E.
   Borda, Luis J.
   Bhagwandin, Stephanie
   Paredes, Juan A.
   Polanco, Thais
   Lantis, John C., II
   Kim, Paul J.
   Phillips, Tania J.
   Kirsner, Robert S.
TI A Novel Topical Wound Therapy Delivery System
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE topical delivery system; wound dressing; negative pressure wound
   therapy; wound irrigation
ID INTRALESIONAL SODIUM THIOSULFATE; VACUUM-ASSISTED CLOSURE; THICKNESS
   WOUNDS; CLINICAL-TRIAL; BETA-BLOCKER; CALCIPHYLAXIS; INSTILLATION;
   INFLAMMATION; STANOZOLOL; DRESSINGS
AB Introduction. Wound care dressings have, evolved over time, from bandaging to the development of occlusive dressings to negative pressure wound therapy. A novel therapeutic delivery syStem dressing has been cleared by the United States Food and Drug Administration. This semi occlusive wound dressing has been, developed to provide local, continuous delivery of aqueous topical agents, such as therapeutics (anes-thetics, antiseptics, antibiotics, steroids, topical bet-blockers, immune modulatory agents, growth factors, and fibrinolytic agents, among others), at a rate of about 3/4 mL per day, thus maintaining a hydrated environment and providing topical treatment. This type of system may be beneficial in situations where systemic therapies cannot be used, wounds are small and few, wounds may need frequent application of medication or moisture, or low and steady delivery of medications is needed. Objective. The authors assessed a delivery system dressing with different types of liquid medications for the management of hard-to-heal, chronic lower extremity wounds. Materials and Methods. Patients aged >= 18 ands <= 90 years with stalled chronic wounds > 30 days' duration were selected for the use of a topical delivery system, which consists of a semi occlusive wound dressing and fluid delivery unit that can provide local application of small therapeutic quantities of medication directly to the wound. Results. Several successful cases with the use of this device are presented in which pain, relief., enhancement of epithelial migration, inflammation reduction, bacterial control, and wound size reduction were achiieved. Conclusions. This delivery system dressing is an effective and safe treatment option for wounds. Advantages include reduced potential of systemic side effects, flexibility in what can be delivered, constant rate of medication delivery, and convenience.
C1 [Herskovitz, Ingrid; MacQuhae, Flor E.; Borda, Luis J.; Kirsner, Robert S.] Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, 1600 NW 10th Ave,Rosenstiel Med Sci Bldg, Miami, FL 33136 USA.
   [Bhagwandin, Stephanie; Paredes, Juan A.; Polanco, Thais; Lantis, John C., II] Mt Sinai St Lukes Hosp, New York, NY USA.
   [Kim, Paul J.] MedStar Georgetown Univ Hosp, Dept Plast Surg, Washington, DC USA.
   [Phillips, Tania J.] Boston Univ, Sch Med, Boston Med Ctr, Dermatol Wound Clin, Boston, MA 02118 USA.
C3 University of Miami; Mount Sinai Morningside; Georgetown University;
   Boston Medical Center; Boston University
RP Kirsner, RS (通讯作者)，Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, 1600 NW 10th Ave,Rosenstiel Med Sci Bldg, Miami, FL 33136 USA.
EM Rkirsner@miami.edu
OI Phillips, Tania/0000-0003-2744-4931; , Paul/0000-0002-6186-6890
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NR 45
TC 4
Z9 4
U1 0
U2 10
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD SEP
PY 2017
VL 29
IS 9
BP 269
EP 276
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA FJ0CR
UT WOS:000412376600005
PM 28933696
DA 2026-07-24
ER

PT J
AU Mullally, C
   Carey, K
   Seshadri, R
AF Mullally, Colleen
   Carey, Kim
   Seshadri, Ravi
TI Use of a nanocrystalline silver dressing and vacuum-assisted closure in
   a severely burned dog
SO JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE
LA English
DT Article
DE negative pressure wound therapy; silver dressings; thermal burns
ID TOPICAL NEGATIVE-PRESSURE; SUBATMOSPHERIC PRESSURE; SMOKE EXPOSURE;
   THERMAL BURNS; MANAGEMENT; THERAPY; WOUNDS; CATS
AB Objective - To describe the first veterinary use of a nanocrystalline silver dressing (NSD) and use of vacuum-assisted closure (VAC) to treat a severely burned dog.
   Case or Series Summary - A 1-year-old female intact American Staffordshire Terrier with 50% total body surface area burned was referred for definitive care approximately 18-24 hours post injury. The dog was treated with crystalloid fluids, hydroxyethyl starch, and antimicrobials based on culture and sensitivity results of wound cultures, fresh frozen plasma, human serum albumin, and packed red cells. Wound care initially consisted of daily debridement under anesthesia with silver sulfadiazine application and bandaging. Because of the extent and the location of the wounds and morbid state of the patient, early wound grafting was not an option. Because of its reported improvement in granulation tissue formation and decreased tissue edema, VAC was used once the majority of burned tissue was manually debrided. Because of the pain caused by VAC and traditional bandaging techniques with this extent of injury, an NSD was utilized. This strategy was chosen due to the antimicrobial properties of NSD and the reduced necessity for daily bandage changes, which was reduced to only every 3 days. This protocol reduced the need for daily sedation or anesthesia.
   New or Unique Information Provided - VAC and NSD were used successfully for the treatment of a severe burn injury in a dog. The use of NSD decreased the cost of therapy by reducing the need for daily bandage changes, thereby reducing the anesthetic and analgesic costs and allowing the patient to be managed on an outpatient basis.
C1 [Mullally, Colleen; Carey, Kim] City Angels Vet Specialty Ctr, Culver City, CA 90232 USA.
   [Seshadri, Ravi] Vet Specialty Ctr, Salt Lake City, UT 84106 USA.
RP Mullally, C (通讯作者)，City Angels Vet Specialty Ctr, 9599 Jefferson Blvd, Culver City, CA 90232 USA.
EM colleen_mullally@hotmail.com
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NR 32
TC 29
Z9 31
U1 0
U2 27
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1479-3261
J9 J VET EMERG CRIT CAR
JI J. Vet. Emerg. Crit. Care
PD AUG
PY 2010
VL 20
IS 4
BP 456
EP 463
DI 10.1111/j.1476-4431.2010.00564.x
PG 8
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA 642JF
UT WOS:000281207500013
PM 20731813
DA 2026-07-24
ER

PT J
AU Yamashiro, T
   Kushibiki, T
   Mayumi, Y
   Tsuchiya, M
   Ishihara, M
   Azuma, R
AF Yamashiro, Toshifumi
   Kushibiki, Toshihiro
   Mayumi, Yoshine
   Tsuchiya, Masato
   Ishihara, Miya
   Azuma, Ryuichi
TI Negative-Pressure Induces Epithelial-Mesenchymal Transition via
   Thrombospondin-1 Upregulation in Intact Diabetic Skin
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE diabetic skin; epithelial-mesenchymal transition; keratinocytes;
   negative-pressure wound therapy; thrombospondin-1; wound remodelling
ID VACUUM-ASSISTED CLOSURE; WOUND THERAPY; SERPINE1 PAI-1;
   MECHANOTRANSDUCTION; KERATINOCYTES; METAANALYSIS; EXPRESSION; MIGRATION;
   EFFICACY; SURGERY
AB Negative-pressure wound therapy (NPWT) is widely used in clinical practise to enhance wound healing; however, its biological effects on intact skin remain poorly understood. Given the expanding applications of NPWT, understanding its impact beyond open wounds is increasingly important. This study aimed to evaluate the biological responses of intact skin to negative-pressure, specifically focusing on epithelial-mesenchymal transition (EMT). The effects of negative-pressure loading were assessed using an in vitro model of non-diabetic human keratinocytes and an in vivo model of intact diabetic mouse skin. Human keratinocytes exposed to negative-pressure exhibited increased expression of thrombospondin-1 (THBS1), transforming growth factor-beta 1 (TGF-beta 1), plasminogen activator inhibitor-1 (PAI-1), and hypoxia-inducible factor 1-alpha (HIF-1 alpha), alongside decreased epithelial markers and increased mesenchymal markers. These EMT-related changes were mitigated by inhibiting the THBS1-TGF-beta 1 interaction. Similarly, in diabetic mice, intermittent negative-pressure loading applied to intact dorsal skin significantly increased THBS1 and TGF-beta 1 levels, resulting in epidermal and dermal thickening, and promoted hypoxic, prothrombotic and angiogenic responses, as evidenced by increased HIF-1 alpha, PAI-1, fibrinogen and vascular endothelial growth factor expression. These findings suggest that negative-pressure loading can induce EMT-like responses and tissue remodelling in intact skin primarily via mechanisms involving the THBS1-TGF-beta 1 signalling axis. This study expands the understanding of the biological influence of NPWT beyond traditional wound treatment applications, potentially informing future therapeutic considerations and safety guidelines.
C1 [Yamashiro, Toshifumi; Tsuchiya, Masato; Azuma, Ryuichi] Natl Def Med Coll, Dept Plast & Reconstruct Surg, Tokorozawa, Saitama, Japan.
   [Kushibiki, Toshihiro; Mayumi, Yoshine; Ishihara, Miya] Natl Def Med Coll, Dept Med Engn, Saitama, Japan.
C3 National Defense Medical College - Japan; National Defense Medical
   College - Japan
RP Yamashiro, T (通讯作者)，Natl Def Med Coll, Dept Plast & Reconstruct Surg, Tokorozawa, Saitama, Japan.
EM tyamashiro6328@gmail.com
RI YAMASHIRO, Toshifumi/JJE-7945-2023; Azuma, Ryuichi/AAT-1125-2021
OI Kushibiki, Toshihiro/0000-0002-1705-1467
FU Japan Society for the Promotion of Science [20K12725]
FX This study was partially supported by the JSPS KAKENHI (20K12725).
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NR 55
TC 0
Z9 0
U1 1
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAR 16
PY 2026
VL 23
IS 3
AR e70859
DI 10.1111/iwj.70859
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA FJ7BW
UT WOS:001720373900001
PM 41840929
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Nuutila, K
   Yang, L
   Broomhead, M
   Proppe, K
   Eriksson, E
AF Nuutila, Kristo
   Yang, Lu
   Broomhead, Michael
   Proppe, Karl
   Eriksson, Elof
TI Novel negative pressure wound therapy device without foam or gauze is
   effective at-50 mmHg
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; SUBATMOSPHERIC PRESSURE; GRANULATION-TISSUE;
   BACTERIAL LOAD; INSTILLATION; JELONET; BURNS
AB Negative pressure wound therapy (NPWT) promotes healing in acute or chronic wounds. Conventional NPWT devices consist of a filler (such as foam or gauze) that covers the wound and of a permeable membrane and tubing that connects the space under the membrane to a suction pump. The permeable membrane increases airflow and thus increases the required pump capacity that can cause patient discomfort or even ischemia in wounds with compromised vascularity. In addition, foam or gauze may fragment and become colonized with bacteria over time. To mitigate these, negative aspects, we have developed a new impermeable single layer component membrane dressing to deliver NPWT that does not need a foam or gauze to function. Therefore, the purpose of this study was to introduce this novel NPWT system (platform wound device, PWD) and evaluate its usability and effectiveness in the treatment of porcine full-thickness burns. A total of 48 burn wounds were created across four Yorkshire pigs on the dorsum. Wounds were created on day 0 and continuous NPWT with -50 mmHg and - 80 mmHg was initiated immediately. Subsequently, the burns were debrided on day 3 and animals were euthanized on day 7. The efficacy of the PWD on wound healing and reduction of bacterial burden was measured and compared to wounds that did not receive NPWT. The results showed that PWD promoted wound healing by outperforming the wounds that did not receive NPWT and that PWD was efficient at reducing bacteria from the burn eschar and from the wound bed. In conclusion, this study demonstrated that PWD promoted wound healing with a negative pressure as low as -50 mmHg, which likely benefits healing and avoids potential safety issues.
C1 [Nuutila, Kristo; Yang, Lu; Broomhead, Michael; Proppe, Karl; Eriksson, Elof] Appl Tissue Technol LLC, Hingham, MA 02043 USA.
RP Nuutila, K; Eriksson, E (通讯作者)，Appl Tissue Technol LLC, Hingham, MA 02043 USA.
EM kristo.nuutila@gmail.com; elof@comcast.net
FU USAMRAA [W81XWH-14-C-0015]
FX The views, opinions and/or findings contained in this report are those
   of the author(s) and should not be construed as an official Department
   of the Army position, policy or decision unless so designated by other
   documentation. This material is based upon work supported by the USAMRAA
   under Contract No W81XWH-14-C-0015.
CR Anghel EL, 2016, PLAST RECONSTR SURG, V138, p129S, DOI 10.1097/PRS.0000000000002645
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NR 39
TC 19
Z9 23
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR-APR
PY 2019
VL 27
IS 2
BP 162
EP 169
DI 10.1111/wrr.3
PG 8
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA HP5ND
UT WOS:000461722900003
PM 30378215
DA 2026-07-24
ER

PT J
AU Michalczyk, L
   Grabinska, A
   Banaczyk, B
   Braszko, M
   Andrychowicz, A
   Zabkowski, T
AF Michalczyk, Lukasz
   Grabinska, Agnieszka
   Banaczyk, Beata
   Braszko, Marek
   Andrychowicz, Aneta
   Zabkowski, Tomasz
TI Efficiency of Hyperbaric Oxygen Therapy Combined with Negative-Pressure
   Wound Therapy in the Treatment Strategy of Fournier's Gangrene -A
   Retrospective Study
SO UROLOGY JOURNAL
LA English
DT Article
DE Fournier Gangrene; treatment; wounds
ID VACUUM-ASSISTED CLOSURE
AB Purpose: Fournier's gangrene (FG) is a serious, aggressive, and often fatal multi-organism infection that affects the soft tissues of the perineum, rectum, and external genitalia. This study aimed to analyse the treatment's strategies of FG.
   Materials and Methods: This was a retrospective study of 35 patients with a diagnosis of FG admitted between 2016 and 2021. The diagnosis of FG was established on a clinical basis. Data on patient's age, sex, comorbidities, laboratory results (C-reactive protein (CRP), white blood cell (WBC), hematocrit (HCT), platelets (PLT), sodium, potassium, creatinine, procalcitonin, international normalized ratio (INR), and gangrene culture), extent of resection, antibiotics used, and hospitalisation time were obtained. The extent of resection was assessed on a scale of 1-5.
   Results: The study group consisted of all men (n=35) aged 24-85 (mean, 58) years. In 13/35 (37%) patients, hyperbaric oxygen therapy (HBOT) combined with negative-pressure wound therapy (NPWT) was used as a treatment for wound healing in Fournier's syndrome (group 1), and in 22/35 (63%) patients, open standard wound care was used (group 2). There were no fatalities in group 1, but four deaths (18%) were noted in group 2. The median extent of resection was 3 in group 1 and 2 in group 2. There was a correlation between the extent of resection and the use of HBOT combined with NPWT. The hospitalisation time was much shorter in group 2 (mean, 23 days) than in group 1 (mean, 26 days).
   Conclusion: HBOT and NPWT (group 1) showed advanced wound healing with a high efficiency rate. The longer median hospitalisation time in this group may be related to the severity of the injury.
C1 [Michalczyk, Lukasz; Banaczyk, Beata; Braszko, Marek] Praski Hosp, Dept Urol & Oncol Urol, Warsaw, Poland.
   [Grabinska, Agnieszka; Zabkowski, Tomasz] Mil Inst Med, Dept Urol, Warsaw, Poland.
   [Andrychowicz, Aneta; Zabkowski, Tomasz] Urol Outpatient Clin, Warsaw, Poland.
C3 Military Institute of Aviation Medicine
RP Michalczyk, L (通讯作者)，Praski Hosp, Dept Urol & Oncol Urol, Warsaw, Poland.
EM lukamichalczyk@gmail.com
RI Zabkowski, Tomasz/H-8645-2018
CR Assenza M, 2011, CLIN TER, V162, pE1
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NR 12
TC 9
Z9 10
U1 0
U2 4
PU UROL & NEPHROL RES CTR-UNRC
PI TEHRAN
PA NO 44, 9TH BOUSTAN ST, PASADARAN AVE, TEHRAN, 00000, IRAN
SN 1735-1308
EI 1735-546X
J9 UROL J
JI Urol. J.
PD JUL-AUG
PY 2022
VL 19
IS 4
BP 329
EP 332
DI 10.22037/uj.v18i.6797
PG 4
WC Urology & Nephrology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Urology & Nephrology
GA 6S3DO
UT WOS:000892871700005
PM 34399437
DA 2026-07-24
ER

PT J
AU Dong, JY
   Qing, C
   Song, F
   Wang, XQ
   Lu, SL
   Tian, M
AF Dong, Jiaoyun
   Qing, Chun
   Song, Fei
   Wang, Xiqiao
   Lu, Shuliang
   Tian, Ming
TI Potential molecular mechanisms of negative pressure in promoting wound
   healing
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Cdc42; EGF; IFN-gamma; keratinocytes; negative pressure wound therapy;
   neutrophils; wound healing
ID VACUUM-ASSISTED-CLOSURE; TNF-ALPHA; IFN-GAMMA; THERAPY; FOOT;
   DEBRIDEMENT; NEUTROPHILS; EXPRESSION; CELLS; CDC42
AB Negative pressure wound therapy (NPWT) has been widely used in various lesions. This study aimed to explore the biological effects of negative pressure on the polymorphonuclear neutrophils (PMNs), macrophages, and epidermal keratinocyte cells involved in wound healing. PMNs differentiated from HL-60, macrophages were derived from THP-1 monocytes, and keratinocytes were cultured in vitro, and they were treated with 0, -0.03 mp, and -0.05 mp, respectively. Cell ultrastructure; viability; apoptosis; and protein factors such as tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), epidermal growth factor (EGF), epidermal growth factor receptor (EGFR), interleukin-17 (IL-17), and cell division cycle 42 (Cdc42) were determined by transmission electron microscopy (TEM), CCK8, flow cytometry (FCM), ELISA, and simple Western assays, respectively. After negative pressure stimulation, the cell ultrastructure of PMNs and macrophages cells was presented with a marked increase of lysosomes and a relative decrease of mitochondria. In addition, the cell viability was enhanced in PMNs and macrophages in a pressure-dependent manner and apoptosis ratios were significantly reduced in PMNs and macrophages. In addition, under -0.05 negative pressure, IFN-gamma and IL-17 were significantly increased in PMNs or macrophages. Moreover, increased EGF and EGFR and Cdc42 levels in keratinocytes induced by the -0.05 mpa were detected, indicating that the migration chemotaxis of keratinocyte cells was enhanced. Negative pressure might promote cell proliferation, accelerate inflammatory responses, and promote epithelialisation during wound healing by increasing IFN-gamma, IL-17, Cdc42, EGF, and EGFR in PMNs, macrophages, or keratinocytes under different negative pressures.
C1 [Dong, Jiaoyun; Qing, Chun; Song, Fei; Wang, Xiqiao; Lu, Shuliang; Tian, Ming] Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Shanghai Burn Inst, 197 Ruijin Er Rd, Shanghai 20025, Peoples R China.
C3 Shanghai Jiao Tong University
RP Qing, C; Tian, M (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Shanghai Burn Inst, 197 Ruijin Er Rd, Shanghai 20025, Peoples R China.
EM qspring@hotmail.com; tianming198@163.com
RI ; Wang, Xiqiao/U-3100-2019
OI Dong, Jiaoyun/0000-0001-7026-6582; Tian, Ming/0000-0003-1665-321X; 
FU National Natural Science Foundation of China [81670752, 81671916];
   Research and Innovation Project of Shanghai Municipal Education
   Commission [14YZ040]
FX National Natural Science Foundation of China, Grant/Award Numbers:
   81670752, 81671916; Research and Innovation Project of Shanghai
   Municipal Education Commission, Grant/Award Number: 14YZ040
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NR 42
TC 12
Z9 15
U1 0
U2 23
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2020
VL 17
IS 5
BP 1428
EP 1438
DI 10.1111/iwj.13423
EA JUN 2020
PG 11
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA NP6YE
UT WOS:000538863800001
PM 32515909
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Malmsjö, M
   Lindstedt, S
   Ingemansson, R
AF Malmsjo, Malin
   Lindstedt, Sandra
   Ingemansson, Richard
TI Effects on heart pumping function when using foam and gauze for negative
   pressure wound therapy of sternotomy wounds
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; POSTSTERNOTOMY MEDIASTINITIS; AGGRESSIVE
   MANAGEMENT; EARLY INTERVENTION; INCISION; SURGERY; RUPTURE
AB Background: Negative pressure wound therapy (NPWT) has remarkable effects on the healing of poststernotomy mediastinitis. Foam is presently the material of choice for NPWT in this indication. There is now increasing interest in using gauze, as this has proven successful in the treatment of peripheral wounds. It is important to determine the effects of NPWT using gauze on heart pumping function before it can be used for deep sternotomy wounds. The aim was to examine the effects of NPWT when using gauze and foam on the heart pumping function during the treatment of a sternotomy wound.
   Methods: Eight pigs underwent median sternotomy followed by NPWT at -40, -70, -120 and -160 mmHg, using foam or gauze. The heart frequency, cardiac output, mean systemic arterial pressure, mean pulmonary artery pressure, central venous pressure and left atrial pressure were recorded.
   Results: Cardiac output was not affected by NPWT using gauze or foam. Heart frequency decreased during NPWT when using foam, but not gauze. Treatment with foam also lowered the central venous pressure and the left atrial pressure, while gauze had no such effects. Mean systemic arterial pressure, mean pulmonary artery pressure and systemic vascular resistance were not affected by NPWT. Similar haemodynamic effects were observed at all levels of negative pressure studied.
   Conclusions: NPWT using foam results in decreased heart frequency and lower right and left atrial filling pressures. The use of gauze in NPWT did not affect the haemodynamic parameters studied. Gauze may thus provide an alternative to foam for NPWT of sternotomy wounds.
C1 [Malmsjo, Malin] Univ Lund Hosp, Dept Ophthalmol, S-22185 Lund, Sweden.
   [Lindstedt, Sandra; Ingemansson, Richard] Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital
RP Malmsjö, M (通讯作者)，Univ Lund Hosp, Dept Ophthalmol, S-22185 Lund, Sweden.
EM malin.malmsjo@med.lu.se
RI ; Lindstedt, Sandra/AEM-2892-2022
OI Ingemansson, Richard/0000-0001-7623-8953; Maljö,
   Malin/0000-0001-9849-9599; Lindstedt, Sandra/0000-0003-4484-6473
FU Ake-Wieberg Foundation; Magn Bergvall Foundation; Swedish Medical
   Association; Royal Physiographic Society in Lund; Crafoord Foundation;
   Swedish Heart-Lung Foundation; Swedish Hypertension Society; Smith &
   Nephew Wound Management
FX This study was funded by Ake-Wieberg Foundation, the Magn Bergvall
   Foundation, the Swedish Medical Association, the Royal Physiographic
   Society in Lund, the Crafoord Foundation, the Swedish Heart-Lung
   Foundation, the Swedish Hypertension Society and Smith & Nephew Wound
   Management.
CR Abu-Omar Y, 2003, ANN THORAC SURG, V76, P974, DOI 10.1016/S0003-4975(03)00180-2
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NR 22
TC 1
Z9 2
U1 0
U2 5
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD JAN 13
PY 2011
VL 6
AR 5
DI 10.1186/1749-8090-6-5
PG 6
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 714TH
UT WOS:000286831400001
PM 21232105
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Berger, P
   de Bie, D
   Moll, FL
   de Borst, GJ
AF Berger, Paul
   de Bie, Dennis
   Moll, Frans L.
   de Borst, Gert-Jan
TI Negative pressure wound therapy on exposed prosthetic vascular grafts in
   the groin
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Article
ID VACUUM ASSISTED CLOSURE; INFECTIONS; MANAGEMENT; FLAPS
AB Objective: This study assessed the outcome of vacuum-assisted closure (VAC) as primary therapy for exposed prosthetic vascular grafts in the groin (Szilagyi III).
   Methods: The study included all consecutive patients with Szilagyi III groin infections and exposed prosthetic graft material from 2009 to 2011. After initial wound debridement, VAC was applied using a two-layer combination, consisting of polyvinyl alcohol and polyurethane sponges. Continuous negative pressure was set on a maximum of 50 mm Hg. All patients received complementary antibiotic therapy. The primary end point was defined as complete wound closure. Secondary end points comprised bleeding complications, amputation, and death.
   Results: The study evaluated 15 patients with 17 Szilagyi III groin infections. Mean total length of VAC therapy was 43 days (range, 14-76 days). Mean time until complete healing was 51 days (range, 24-82 days). Mean length of VAC therapy in the hospital was 21 days (range, 5-61 days). Eleven patients received continued VAC treatment at home for a mean length of 22 days (range, 5-69 days). Complete healing was achieved in 14 groins (82%). Three failures due to persisting infection, persisting necrosis, and a pseudomonas infection were noted. No bleeding complications, amputations, or late reinfections occurred. Median follow-up was 380 days (range, 56-939 days). Despite therapy failure, all 17 grafts were preserved.
   Conclusions: VAC therapy on an exposed prosthetic vascular graft in the groin is safe and feasible when applying a combination of polyvinyl alcohol and polyurethane foam dressing and 50 mm Hg of continuous negative pressure, resulting in midterm graft preservation. (J Vasc Surg 2012;56:714-20.)
C1 [Berger, Paul; de Bie, Dennis; Moll, Frans L.; de Borst, Gert-Jan] Univ Med Ctr Utrecht, Dept Vasc Surg, NL-3508 GA Utrecht, Netherlands.
C3 Utrecht University; Utrecht University Medical Center
RP Berger, P (通讯作者)，Univ Med Ctr Utrecht, Dept Vasc Surg, G04-129,POB 85500, NL-3508 GA Utrecht, Netherlands.
EM p.berger@umcutrecht.nl
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NR 18
TC 26
Z9 31
U1 0
U2 7
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
J9 J VASC SURG
JI J. Vasc. Surg.
PD SEP
PY 2012
VL 56
IS 3
BP 714
EP 720
DI 10.1016/j.jvs.2012.02.007
PG 7
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA 996KM
UT WOS:000308085500018
PM 22554424
DA 2026-07-24
ER

PT J
AU Kabir, I
   Nguyen, T
   Heaton, J
   Peterson, K
   Martyak, M
AF Kabir, Ishraq
   Nguyen, Tuan
   Heaton, Julia
   Peterson, Kristen
   Martyak, Michael
TI Incisional Negative Pressure Wound Therapy to Decrease the Incidence of
   Surgical Site Infections in Trauma Laparotomy Wounds
SO AMERICAN SURGEON
LA English
DT Article
AB Background Surgical site infection (SSI) is a common post-operative complication, especially in trauma laparotomies. Incisional negative pressure wound therapy (iNPWT) is a novel technique in reducing SSIs. We aim to study the rate of wound complications in trauma laparotomy with standard primary closure with staples vs iNPWT. Methods We had 152 patients meeting inclusion criteria who underwent emergent trauma laparotomies performed at Sentara Norfolk General from 2017 to 2020. We had 79 patients in the standard staple group and 73 patients in the iNWPT group. We then analyzed surgical site infection rates and wound complication rates in both groups within a 30-day period. Results The wound infection rate in the staple vs staple plus iNPWT was 10.0% vs 3.8%, respectively (P = .13). Wound dehiscence rates were 24.1% vs 10.13%, respectively (P = .02). When looking at a subset of patients with hollow viscous injury, the rate of SSIs was statistically lower in the iNPWT group. Prior to the introduction of the incisional vacuum-assisted closure (VAC) to our practice compared to after its introduction, 39.25% of wounds were left open vs 19.51%, respectively (P = .001). Conclusion Our data identified a trend toward a decrease in overall SSIs in trauma laparotomies closed with iNPWT. The use of iNPWT demonstrated a decrease in superficial wound dehiscence and a decrease in SSIs in patients with associated full thickness bowel injury. With iNPWT, we are more aggressive with primarily closing trauma laparotomy wounds. This shows promise for increasing primary closure rates while simultaneously decreasing overall superficial surgical site infection rate.
C1 [Kabir, Ishraq; Nguyen, Tuan; Heaton, Julia; Peterson, Kristen; Martyak, Michael] Eastern Virginia Med Sch, Hoffheimer Hall,825 Fairfax Ave,Suite 610, Norfolk, VA 23501 USA.
C3 Eastern Virginia Medical School
RP Kabir, I (通讯作者)，Eastern Virginia Med Sch, Hoffheimer Hall,825 Fairfax Ave,Suite 610, Norfolk, VA 23501 USA.
EM Ishraqkabir4@gmail.com
CR Chadi SA, 2015, TRIALS, V16, DOI 10.1186/s13063-015-0817-8
   Durbin S, 2019, J SURG RES, V243, P496, DOI 10.1016/j.jss.2019.06.101
   Gomoll AH, 2006, J ORTHOP TRAUMA, V20, P705, DOI 10.1097/01.bot.0000211159.98239.d2
   Hall C, 2019, J AM COLL SURGEONS, V228, P393, DOI 10.1016/j.jamcollsurg.2018.12.006
   Ke CY, 2017, J BIOMED INFORM, V65, P22, DOI 10.1016/j.jbi.2016.10.021
   Morales CH, 2011, CAN J SURG, V54, P17, DOI 10.1503/cjs.022109
NR 6
TC 5
Z9 5
U1 0
U2 0
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0003-1348
EI 1555-9823
J9 AM SURGEON
JI Am. Surg.
PD MAY
PY 2023
VL 89
IS 5
BP 1908
EP 1911
AR 00031348211054529
DI 10.1177/00031348211054529
EA APR 2022
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA J0VE5
UT WOS:000779358900001
PM 35384733
DA 2026-07-24
ER

PT J
AU Zheng, SW
   Huang, XM
   Lin, YZ
   Chen, XH
   Lin, GH
   Zhuang, J
AF Zheng, Shengwu
   Huang, Xiongmei
   Lin, Yazhou
   Chen, Xiaohui
   Lin, Genhui
   Zhuang, Jing
TI Negative-pressure wound therapy (NPWT) for the treatment of pacemaker
   pocket infection in patients unable or unwilling to undergo CIED
   extraction
SO JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
LA English
DT Article
DE Pacemaker pocket infection; Treatment; NPWT; Retained CIED; Cardiology
ID ELECTRONIC DEVICE INFECTIONS; VACUUM-ASSISTED CLOSURE;
   CARDIOVERTER-DEFIBRILLATORS; MANAGEMENT; DIAGNOSIS; PREVENTION;
   GUIDELINES; TRENDS; RATES
AB Purpose The occurrence of cardiac pacemaker pocket infection has markedly increased and has become a new problem facing cardiovascular internists. The aim of our study was to investigate the effectiveness and safety of treating cardiac pacemaker pocket infection using negative-pressure wound therapy (NPWT) in patients who are unwilling or unable to have their cardiac implantable electronic devices (CIEDs) removed. Methods From March 2013 to April 2019, NPWT was applied to 26 patients with cardiac pacemaker pocket infection who were unwilling or unable to have their CIEDs removed. In the first stage, a negative-pressure drainage system was placed in the pacemaker pocket after debridement. Then, NPWT was used to seal the wound, and the negative pressure (300-400 mmHg) was sustained for 5-7 days. In the second stage, the pacemaker was relocated to the subpectoral layer, and the wound was closed. Results In all but three of our 26 patients, the wound healed completely without complications and without evidence of residual infection. The average follow-up period was 26.92 +/- 9.46 months. Only 3 diabetic patients whose tissue bacterial cultures revealed that methicillin-resistantStaphylococcus epidermidisdeveloped uncontrolled infections. Eventually, the entire original pacemaker systems were removed, and new pacemakers were implanted in the contralateral chest wall. Conclusions When warranted by strictly selected indications, the method of NPWT without CIED extraction can be considered as a new and effective treatment for patients with pacemaker pocket infection who are unwilling or unable to have the device removed.
C1 [Zheng, Shengwu; Huang, Xiongmei; Lin, Genhui; Zhuang, Jing] Fujian Med Univ, Shengli Clin Med Coll, Dept Burn & Plast Surg, Fujian Prov Hosp, 134 St East, Fuzhou 350001, Peoples R China.
   [Lin, Yazhou] Fujian Med Univ, Fujian Prov Hosp, Shengli Clin Med Coll, Dept Cardiol,Fujian Heart Dis Res Inst, Fuzhou, Peoples R China.
   [Chen, Xiaohui] Fujian Med Univ, Fujian Prov Hosp, Shengli Clin Med Coll, Dept Anesthesiol, Fuzhou, Peoples R China.
C3 Fujian Medical University; Fujian Provincial Hospital; Fujian Medical
   University; Fujian Provincial Hospital; Fujian Medical University;
   Fujian Provincial Hospital
RP Zheng, SW (通讯作者)，Fujian Med Univ, Shengli Clin Med Coll, Dept Burn & Plast Surg, Fujian Prov Hosp, 134 St East, Fuzhou 350001, Peoples R China.
EM dr.zhengshengwu@yahoo.com
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NR 38
TC 7
Z9 9
U1 0
U2 3
PU SPRINGER
PI DORDRECHT
PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
SN 1383-875X
EI 1572-8595
J9 J INTERV CARD ELECTR
JI J. Interv. Card. Electrophysiol.
PD AUG
PY 2021
VL 61
IS 2
BP 245
EP 251
DI 10.1007/s10840-020-00805-y
EA JUN 2020
PG 7
WC Cardiac & Cardiovascular Systems
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA TS5WU
UT WOS:000542099300001
PM 32572720
OA hybrid
DA 2026-07-24
ER

PT J
AU Steigelman, MB
   Norbury, KC
   Kilpadi, DV
   McNeil, JD
AF Steigelman, Megan B.
   Norbury, Kenneth C.
   Kilpadi, Deepak V.
   McNeil, Jeffrey D.
TI Cardiopulmonary Effects of Continuous Negative Pressure Wound Therapy in
   Swine
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; PERISTERNAL THORACIC WALL; RIGHT-VENTRICULAR
   RUPTURE; BLOOD-FLOW; POSTSTERNOTOMY MEDIASTINITIS; CARDIAC-SURGERY;
   STERNAL WOUNDS; MANAGEMENT; DEVICE; BRIDGE
AB Background. Negative pressure wound therapy (NPWT) has been used for complex sternotomy wounds. Some reports describe foam placement below the posterior sternal table. We compared the hemodynamic and pulmonary effects of foam location during NPWT after median sternotomy.
   Methods. Swine were randomized into four groups (n = 6 per group). A polyurethane open cell foam dressing was placed either within or below the sternal table. In one-half, a silicone mesh barrier was placed between the heart and the foam. The NPWT was applied at -125 mm Hg and then released to ambient pressure. This cycle was repeated two more times, and the foam was removed. Heart rate, mean arterial pressure, cardiac output, mixed venous oxygenation, central venous pressure, and pulmonary artery wedge pressure were measured. Peak inspiratory pressure, mean airway pressure, work of breathing, and intrathoracic pressure measurements were recorded.
   Results. Intersternal placement of foam did not affect hemodynamic parameters. Substernal placement resulted in depression of hemodynamic variables which improved when negative pressure was applied. Pulmonary mechanics were not affected by foam location.
   Conclusions. Initial placement of the foam dressing below the posterior sternal table caused reversible depression of cardiac function which appears to be consistent with direct cardiac compression. NPWT therapy had no clinically significant impact on pulmonary parameters. The use of a protective barrier does not alter hemodynamic or pulmonary parameters but continues to be recommended when NPWT is used for sternotomy wounds. (Ann Thorac Surg 2009; 88: 1277-83) (C) 2009 by The Society of Thoracic Surgeons
C1 [McNeil, Jeffrey D.] Univ Texas Hlth Sci Ctr San Antonio, Div Cardiothorac Surg, Dept Surg, San Antonio, TX 78229 USA.
   Wilford Hall USAF Med Ctr, Dept Surg, Lackland AFB, TX 78236 USA.
   Global R& Kinet Concepts Inc, Dept Physiol & Models, San Antonio, TX USA.
C3 University of Texas System; University of Texas at San Antonio; United
   States Department of Defense; United States Air Force
RP McNeil, JD (通讯作者)，Univ Texas Hlth Sci Ctr San Antonio, Div Cardiothorac Surg, Dept Surg, 7703 Floyd Curl Dr, San Antonio, TX 78229 USA.
EM mcneil@uthscsa.edu
FU Cooperative Research and Development Agreement between Wilford Hall
   Medical Center and Kinetic Concepts Inc
FX The authors wish to thank SSgt Tanya Green, Gene Deck, Barbara Collins,
   and Crissy Jenschke for their technical assistance, Mark Borromeo for
   preparing the figures, Zhenmei Liu for statistical analysis, and George
   Hutchinson, Margaret Marsh, Shannon Crenshaw, Nadeem Bridi, Deborah
   Shanley, and Royce Johnson for reviewing the manuscript. The opinions
   expressed in this paper are solely those of the authors and do not
   represent the views of the United States Air Force, United States
   Department of Defense, or the United States Government. This project was
   entirely supported by a Cooperative Research and Development Agreement
   between Wilford Hall Medical Center and Kinetic Concepts Inc.
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   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
NR 23
TC 6
Z9 6
U1 0
U2 12
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD OCT
PY 2009
VL 88
IS 4
BP 1277
EP 1283
DI 10.1016/j.athoracsur.2009.06.027
PG 7
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 501NL
UT WOS:000270388500034
PM 19766821
OA Bronze
DA 2026-07-24
ER

PT J
AU Ockerman, KM
   Cox, EA
   Wiesemann, G
   Nichols, DS
   Murad, GJA
   Ching, J
   Sorice-Virk, S
AF Ockerman, Kyle M.
   Cox, Elizabeth A.
   Wiesemann, Gayle
   Nichols, D. Spencer
   Murad, Gregory J. A.
   Ching, Jessica
   Sorice-Virk, Sarah
TI Healing Exposed Calvarial Hardware Using Negative-Pressure Wound Therapy
   and Vashe Wound Solution: Case Report
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
DE cranial reconstruction; cranioplasty; hypochlorous acid solution;
   infection; syndrome of the trephined; vacuum-assisted closure; Vashe
   Wound Solution
ID CRANIOPLASTY; INFECTIONS; MANAGEMENT; FLAP
AB OBJECTIVEThe management of cranioplasty infections has historically been explantation followed by delayed reimplantation/reconstruction. This treatment algorithm necessitates surgery, tissue expansion, and prolonged disfigurement. In this report, the authors describe a treatment approach consisting of serial vacuum-assisted closure (VAC) with hypochlorous acid (HOCl) solution (Vashe Wound Solution; URGO Medical) as a salvage strategy.METHODSA 35-year-old man who sustained head trauma, neurosurgical complications, and severe syndrome of the trephined (SOT; devastating neurologic decline treated by cranioplasty) underwent titanium cranioplasty with free flap. Three weeks postoperation, he presented with pressure-related wound dehiscence/partial flap necrosis, exposed hardware, and bacterial infection. Given the severity of his precranioplasty SOT, hardware salvage was critical. He was treated with serial VAC with HOCl solution for 11 days followed by VAC for 18 days and definitive split-thickness skin graft placement over resulting granulation tissue. Authors also conducted a literature review of cranial reconstruction infection management.RESULTSThe patient remained healed 7 months postoperatively without recurrent infection. Importantly, his original hardware was retained, and his SOT remained resolved. Findings from the literature review support the use of conservative modalities to salvage cranial reconstructions without hardware removal.CONCLUSIONSThis study investigates a new strategy for managing cranioplasty infections. The VAC with HOCl solution regimen was effective in treating the infection and salvaging the cranioplasty, thus obviating the complications associated with explantation, new cranioplasty, and recurrence of SOT. There is limited literature on the management of cranioplasty infections using conservative treatments. A larger study to better determine the efficacy of VAC with HOCl solution is underway.
C1 [Ockerman, Kyle M.; Wiesemann, Gayle] Univ Florida, Coll Med, Gainesville, FL 32610 USA.
   [Murad, Gregory J. A.] Univ Florida, Coll Med, Dept Neurosurg, Gainesville, FL USA.
   [Ching, Jessica; Sorice-Virk, Sarah] Univ Florida, Coll Med, Div Plast & Reconstruct Surg, Gainesville, FL USA.
   [Cox, Elizabeth A.] Stanford Univ, Sch Med, Div Plast & Reconstruct Surg, Palo Alto, CA USA.
   [Nichols, D. Spencer] Duke Univ, Sch Med, Div Plast & Reconstruct Surg, Durham, NC USA.
C3 State University System of Florida; University of Florida; State
   University System of Florida; University of Florida; State University
   System of Florida; University of Florida; Stanford University; Duke
   University
RP Ockerman, KM (通讯作者)，Univ Florida, Coll Med, Gainesville, FL 32610 USA.
OI Nichols, D. Spencer/0000-0003-4657-7844; Ockerman,
   Kyle/0000-0002-6500-6740
CR Agner C, 2002, ACTA NEUROCHIR, V144, P1033, DOI 10.1007/s00701-002-0996-4
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   Frassanito P, 2019, CHILD NERV SYST, V35, P1499, DOI 10.1007/s00381-019-04251-8
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   Yeap MC, 2019, WORLD NEUROSURG, V128, pE841, DOI 10.1016/j.wneu.2019.05.005
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   Zhao JY, 2018, WORLD NEUROSURG, V112, pE514, DOI 10.1016/j.wneu.2018.01.070
NR 32
TC 2
Z9 2
U1 1
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD JUL
PY 2023
VL 36
IS 7
BP 385
EP 391
DI 10.1097/01.ASW.0000926628.10995.fc
PG 7
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA K3DP2
UT WOS:001015279500012
PM 37224465
DA 2026-07-24
ER

PT J
AU Bertelsen, CA
   Fabricius, R
   Kleif, J
   Kristensen, B
   Gögenur, I
AF Bertelsen, Claus Anders
   Fabricius, Rasmus
   Kleif, Jakob
   Kristensen, Bent
   Gogenur, Ismail
TI Outcome of Negative-Pressure Wound Therapy for Open Abdomen Treatment
   After Nontraumatic Lower Gastrointestinal Surgery: Analysis of Factors
   Affecting Delayed Fascial Closure in 101 Patients
SO WORLD JOURNAL OF SURGERY
LA English
DT Article
ID ABDOMINAL COMPARTMENT SYNDROME; VACUUM-ASSISTED CLOSURE; DAMAGE CONTROL;
   INTESTINAL WALL; MANAGEMENT; MESH; LAPAROSTOMY; TRACTION
AB Few studies have focused on the risk factors for failure to achieve fascial closure after use of negative-pressure wound therapy (NPWT) in an open abdomen (OA). We aimed at analyzing possible risk factors for failure of fascial closure and the risk of fistulas after nontrauma lower gastrointestinal (GI) tract surgery treated with OA.
   This retrospective study included 101 nontrauma patients treated with OA from 2007 to 2011. Multivariate analyses of risk factors were performed.
   Indications for OA were diffuse peritonitis (n = 47), need for second look (n = 26), failure to achieve fascial closure (e.g., bowel edema) at primary laparotomy (n = 24), and fascial necrosis (n = 4). Of the 101 patients, 61 (60 %) were alive at discharge, with one death possibly related to OA (fistula from an iatrogenic perforation). Delayed fascial closure was obtained in 40 (66 %) of the surviving patients, with 80 % when the indications for OA was need for second look and 72 % in cases of diffuse peritonitis. Compared with need for second look [hazard ratio (HR = 1), 95 % CI], proportional HR for failure of delayed fascial closure were peritonitis 1.96 (1.10-3.49) and failure to achieve fascial closure at primary laparotomy 4.70 (2.17-10.2). In the presence of a stoma the HR was 2.02 (1.13-3.63).
   OA using NPWT seems to be a safe procedure, with few procedure-related complications. Failure of fascial closure is related to the indication of OA and the presence of a stoma. Prospective multicenter studies are needed to establish which patients with lower GI surgery benefit from OA.
C1 [Bertelsen, Claus Anders; Fabricius, Rasmus; Kleif, Jakob; Gogenur, Ismail] Univ Copenhagen, Hillerod Univ Hosp, Dept Surg, DK-3400 Hillerod, Denmark.
   [Kristensen, Bent] Univ Copenhagen, Hillerod Univ Hosp, Dept Clin Physiol & Nucl Med, DK-3400 Hillerod, Denmark.
   [Gogenur, Ismail] Univ Copenhagen, Herlev Univ Hosp, Dept Surg, DK-2730 Herlev, Denmark.
C3 University of Copenhagen; University of Copenhagen; University of
   Copenhagen; Herlev & Gentofte Hospital
RP Bertelsen, CA (通讯作者)，Univ Copenhagen, Hillerod Univ Hosp, Dept Surg, Dyrehavevej 29, DK-3400 Hillerod, Denmark.
EM cabertelsen@gmail.com
RI ; Bertelsen, Claus Anders/AAZ-8209-2020
OI Gögenur, Ismail/0000-0002-3753-268X; Kleif, Jakob/0000-0002-9330-0410;
   Bertelsen, Claus Anders/0000-0001-6337-8447
CR Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
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   Tsuei BJ, 2004, AM SURGEON, V70, P652
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
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NR 34
TC 25
Z9 29
U1 0
U2 7
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD APR
PY 2014
VL 38
IS 4
BP 774
EP 781
DI 10.1007/s00268-013-2360-7
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AD3ND
UT WOS:000333151900004
PM 24337240
DA 2026-07-24
ER

PT J
AU Eyvaz, K
   Kement, M
   Balin, S
   Acar, H
   Kündes, F
   Karaoz, A
   Civil, O
   Eser, M
   Kaptanoglu, L
   Vural, S
   Bildik, N
AF Eyvaz, Kemal
   Kement, Metin
   Balin, Salim
   Acar, Hakan
   Kundes, Fikri
   Karaoz, Alev
   Civil, Osman
   Eser, Mehmet
   Kaptanoglu, Levent
   Vural, Selahattin
   Bildik, Nejdet
TI Clinical evaluation of negative-pressure wound therapy in the management
   of electrical burns
SO ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA &
   EMERGENCY SURGERY
LA English
DT Article
DE Burn; electrical injury; NPWT
ID VACUUM-ASSISTED CLOSURE
AB BACKGROUND: In this study, we aimed to evaluate the clinical efficacy and safety of negative-pressure wound therapy (NPWT) in the treatment of the patients with electrical burns.
   METHODS: This study was retrospectively performed using a database placed prospectively in the burn center of our hospital. All consecutive patients with electrical burns treated using NPWT at our center between August 2008 and December 2012 were included. The treatment results in our study were grouped as successful or unsuccessful considering the treatment objectives in accordance with therapy indications.
   RESULTS: In total, 39 patients were included in our study; of them, 36 (92.3%) were men. The average age was 34.9 +/- 9.8 years (range, 17-63 years). The majority of the patients in our study (92.3%) had been exposed to high voltage electricity. The mean total burned body surface area (TBSA) was 19.3 +/- 9.8 (range, 4-44). Six patients (15.4%) had TBSAs >= 30%, 31 (79.5%) had third degree burns, and 8 (20.5%) had fourth degree burns. In our study, indications of NPWT included bone and/or tendon exposed deep wounds that are not suitable for early grafting or flap applications owing to the lack of supporting tissue in 27 (69.2%) patients, graft fixation in 8 (20.5%) patients, and secondary grafting following graft loss in 4 (10.3%) patients. The general success rate of NPWT was 90.7% according to indications and treatment objectives in our study.
   CONCLUSION: In the light of our results, NPWT may contribute to the present conventional treatments used in severe electrical burns.
C1 [Eyvaz, Kemal; Kement, Metin; Balin, Salim; Acar, Hakan; Kundes, Fikri; Karaoz, Alev; Civil, Osman; Eser, Mehmet; Kaptanoglu, Levent; Vural, Selahattin; Bildik, Nejdet] Kartal Dr Lutfi Kirdar Training & Res Hosp, Univ Hlth Sci, Dept Gen Surg, Istanbul, Turkey.
C3 Istanbul Kartal Dr Lutfi Kirdar Training & Research Hospital; University
   of Health Sciences Turkey
RP Kement, M (通讯作者)，Saglik Bilimleri Univ, Kartal Dr Lutfi Kirdar Training & Res Hosp, Istanbul, Turkey.
EM mkemet@yahoo.com
RI ; Kement, Metin/LNR-5964-2024; Eyvaz, Kemal/W-5052-2017; /AAP-7411-2020
OI Kaptanoglu, Levent/0000-0003-1059-9152; Kement,
   Metin/0000-0003-4724-4945; Eyvaz, Kemal/0000-0002-7410-107X; 
CR [Anonymous], 2 WORLD UN WOUND HEA
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NR 18
TC 10
Z9 15
U1 1
U2 5
PU TURKISH ASSOC TRAUMA EMERGENCY SURGERY
PI ISTANBUL
PA KOPRULU MEHMET PASA SOC, DENIZ ABDAL MAH, DADASOGLU AP, 25-1 SEHREMINI,
   ISTANBUL, 00000, TURKEY
SN 1306-696X
J9 ULUS TRAVMA ACIL CER
JI Ulus. Travma Acil Cerrahi Derg.
PD SEP
PY 2018
VL 24
IS 5
BP 456
EP 461
DI 10.5505/tjtes.2018.80439
PG 6
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA GV9UL
UT WOS:000446506600014
PM 30394501
OA Bronze
DA 2026-07-24
ER

PT J
AU Van Hecke, LL
   Haspeslagh, M
   Hermans, K
   Martens, AM
AF Van Hecke, Lore L.
   Haspeslagh, Maarten
   Hermans, Katleen
   Martens, Ann M.
TI Comparison of antibacterial effects among three foams used with negative
   pressure wound therapy in an ex vivo equine perfused wound model
SO AMERICAN JOURNAL OF VETERINARY RESEARCH
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; EVIDENCE-BASED RECOMMENDATIONS; BACTERIAL LOAD;
   MANAGEMENT; STEPS
AB OBJECTIVE
   To compare antibacterial effects among 3 types of foam used with negative-pressure wound therapy (NPWT) in an ex vivo equine perfused wound model.
   SAMPLES
   Abdominal musculocutaneous flaps from 6 equine cadavers.
   PROCEDURES
   Each musculocutaneous flap was continuously perfused with saline (0.9% NaCl) solution. Four 5-cm circular wounds were created in each flap and contaminated with 10(6) CFUs of both Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA). After a 1-hour incubation period, 1 of 4 treatments (NPWT with silver-impregnated polyurethane foam [NPWT-AgPU], polyurethane foam [NPWT-PU], or polyvinyl alcohol foam [NPWT-PVA] or a nonadherent dressing containing polyhexamethylene biguanide without NPWT [control]) was randomly applied to each wound. An 8-mm punch biopsy specimen was obtained from each wound immediately before and at 6, 12, 18, and 24 hours after treatment application to determine the bacterial load for both P aeruginosa and MRSA.
   RESULTS
   The bacterial load of P aeruginosa for the NPWT-PVA treatment was significantly lower than that for the other 3 treatments at each sampling time after application, whereas the bacterial load for the NPWT-AgPU treatment was significantly lower than that for the NPWT-PU and control treatments at 12 hours after application. The bacterial load of MRSA for the NPWT-PVA treatment was significantly lower than that for the other 3 treatments at each sampling time after application.
   CONCLUSIONS AND CLINICAL RELEVANCE
   Results indicated that wounds treated with NPWT-PVA had the greatest decrease in bacterial load; however, the effect of that treatment on wound healing needs to be assessed in vivo.
C1 [Van Hecke, Lore L.; Haspeslagh, Maarten; Martens, Ann M.] Univ Ghent, Fac Vet Med, Dept Surg & Anaesthesiol Domest Anim, B-9820 Merelbeke, Belgium.
   [Hermans, Katleen] Univ Ghent, Fac Vet Med, Dept Pathol Bacteriol & Poultry Dis, B-9820 Merelbeke, Belgium.
C3 Ghent University; Ghent University
RP Van Hecke, LL (通讯作者)，Univ Ghent, Fac Vet Med, Dept Surg & Anaesthesiol Domest Anim, B-9820 Merelbeke, Belgium.
EM lore.vanhecke@ugent.be
RI Haspeslagh, Maarten/T-8618-2019
OI Haspeslagh, Maarten/0000-0001-6381-590X; Martens,
   Ann/0000-0001-9554-4841
FU Ghent University [01D25512]
FX Supported by the Special Research Fund, Ghent University (grant No.
   01D25512).
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NR 23
TC 15
Z9 16
U1 1
U2 25
PU AMER VETERINARY MEDICAL ASSOC
PI SCHAUMBURG
PA 1931 N MEACHAM RD SUITE 100, SCHAUMBURG, IL 60173-4360 USA
SN 0002-9645
EI 1943-5681
J9 AM J VET RES
JI Am. J. Vet. Res.
PD DEC
PY 2016
VL 77
IS 12
BP 1325
EP 1331
DI 10.2460/ajvr.77.12.1325
PG 7
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA EE2KF
UT WOS:000389412100003
PM 27901391
DA 2026-07-24
ER

PT J
AU Hlebowicz, J
   Hansson, J
   Lindstedt, S
AF Hlebowicz, Joanna
   Hansson, Johan
   Lindstedt, Sandra
TI Microvascular blood flow response in the intestinal wall and the omentum
   during negative wound pressure therapy of the open abdomen
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Article
DE Negative pressure wound therapy; Open abdomen; Microvascular blood flow;
   Intestinal wall; Omentum
ID VACUUM-ASSISTED CLOSURE; ABDOMINAL COMPARTMENT SYNDROME; INTRAABDOMINAL
   HYPERTENSION; MANAGEMENT; FISTULAS
AB Higher closure rates of the open abdomen have been reported with negative pressure wound therapy (NPWT) compared with other wound therapy techniques. However, the method has occasionally been associated with increased development of intestinal fistulae. The present study measures microvascular blood flow in the intestinal wall and the omentum before and during NPWT.
   Six pigs underwent midline incision and application of NPWT to the open abdomen. The microvascular blood flow in the underlying intestinal loop wall and the omentum was recorded before and after the application of NPWT of -50, -70, -100, -120, -150, and -170 mmHg respectively, using laser Doppler velocimetry.
   A significant decrease in microvascular blood flow was seen in the intestinal wall during application of all negative pressures levels. The blood flow was 2.7 (+/- 0.2) Perfusion Units (PU) before and 2.0 (+/- 0.2) PU (*p < 0.05) after application of -50 mmHg, and 3.6 (+/- 0.6) PU before and 1.5 (+/- 0.2) PU (**p < 0.01) after application of -170 mmHg.
   In the present study, we show that negative pressures between -50 and -170 mmHg induce a significant decrease in the microvascular blood flow in the intestinal wall. The decrease in blood flow increased with the amount of negative pressure applied. One can only speculate that a longstanding decreased blood flow in the intestinal wall may induce ischemia and secondary necrosis in the intestinal wall, which, theoretically, could promote the development of intestinal fistulae. We believe that NPWT of the open abdomen is a very effective treatment but could probably be improved.
C1 [Lindstedt, Sandra] Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, S-22185 Lund, Sweden.
   [Hlebowicz, Joanna] Lund Univ, Dept Med, Lund, Sweden.
   [Hlebowicz, Joanna; Lindstedt, Sandra] Skane Univ Hosp, Lund, Sweden.
   [Hansson, Johan] Uppsala Univ, Fac Med, Inst Surg Sci, Uppsala, Sweden.
   [Lindstedt, Sandra] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Lund
   University; Skane University Hospital; Uppsala University; Lund
   University
RP Lindstedt, S (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, S-22185 Lund, Sweden.
EM sandra.lindstedt@skane.se
RI Lindstedt, Sandra/AEM-2892-2022
OI Lindstedt, Sandra/0000-0003-4484-6473
CR Abu-Omar Y, 2003, ANN THORAC SURG, V76, P974, DOI 10.1016/S0003-4975(03)00180-2
   Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
   Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
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   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
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   Stevens P, 2009, INT WOUND J, V6, P259, DOI 10.1111/j.1742-481X.2009.00614.x
   Svensson S, 2008, EUR J VASC ENDOVASC, V36, P84, DOI 10.1016/j.ejvs.2007.12.020
   Swan M C, 2005, J Wound Care, V14, P7
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
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   ZOGRAFOS GC, 1992, ANN SURG, V215, P266, DOI 10.1097/00000658-199203000-00011
NR 34
TC 12
Z9 13
U1 0
U2 5
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0179-1958
EI 1432-1262
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD MAR
PY 2012
VL 27
IS 3
BP 397
EP 403
DI 10.1007/s00384-011-1317-2
PG 7
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 895OX
UT WOS:000300507000016
PM 21938450
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Kugler, NW
   Carver, TW
   Paul, JS
AF Kugler, Nathan W.
   Carver, Thomas W.
   Paul, Jasmeet S.
TI Negative pressure therapy is effective in abdominal incision closure
SO JOURNAL OF SURGICAL RESEARCH
LA English
DT Article
DE Negative pressure wound therapy; VAC; Vacuum-assisted closure; Surgical
   site infection; SSI; Contamination; Dirty; Infected; Enterocutaneous
   fistula; Laparotomy
ID SURGICAL SITE INFECTIONS; WOUND THERAPY; MANAGEMENT-SYSTEM; RISK;
   PREVENTION; EXPERIENCE; SURGERY; SCIP
AB Background: CDC wound classification demonstrates surgical site infection (SSI) occurs in 15%-30% of contaminated (class III) and > 30% of dirty-infected (class IV) wounds. Several techniques have been used to decrease SSI rates in midline laparotomy incisions; however, no technique has shown superiority. Evidence suggests incisional negative pressure wound therapy (INPWT) can decrease wound complications, but no literature exists regarding INPWT for high-risk laparotomy incisions. We sought to analyze the efficacy of INPWT in the management of high-risk midline laparotomy incisions.
   Methods: Retrospective review of adult patients who underwent laparotomy between January 2013 and June 2014 with midline closure using INPWT. Only class III or IV wounds were included. Laparotomy incisions were loosely closed. INPWT set at 125 mm Hg is placed over oil emulsion impregnated gauze. INPWT is removed after 5 d and the wound left open to air. Records were reviewed for immediate and/or delayed surgical site complications. Primary end point was 30-d incisional SSI. Secondary end points included other surgical site complications.
   Results: One class III and 12 class IV wounds were treated with INPWT for a median of 5 d. The class III wound developed a small skin dehiscence with no evidence of superficial or deep SSI. Among class IV wounds, the rate of superficial and deep incisional SSI was 25% and 0%, respectively. The overall surgical site complication rate was 41.7%.
   Conclusions: INPWT in closure of high-risk midline laparotomy incisions is a safe, effective method of wound closure with equivalent SSI rates to previously described methods. (C) 2016 Elsevier Inc. All rights reserved.
C1 [Kugler, Nathan W.; Carver, Thomas W.; Paul, Jasmeet S.] Med Coll Wisconsin, Dept Surg, Div Trauma & Crit Care, Milwaukee, WI 53226 USA.
C3 Medical College of Wisconsin
RP Kugler, NW (通讯作者)，Dept Surg, Div Trauma & Crit Care, 9200 W Wisconsin Ave, Milwaukee, WI 53226 USA.
EM nkugler@mcw.edu
OI Kugler, Nathan/0000-0003-2411-2704; Paul, Jasmeet/0000-0002-4030-6624
FU Department of Surgery; Division of Trauma and Critical care
FX The authors would like to thank the Department of Surgery and the
   Division of Trauma and Critical care for their support in this project.
CR Anderson DJ, 2011, INFECT DIS CLIN N AM, V25, P135, DOI 10.1016/j.idc.2010.11.004
   [Anonymous], INFECT CONTROL HOSP
   Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Colli A, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-160
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NR 17
TC 18
Z9 25
U1 0
U2 8
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0022-4804
EI 1095-8673
J9 J SURG RES
JI J. Surg. Res.
PD JUN 15
PY 2016
VL 203
IS 2
BP 491
EP 494
DI 10.1016/j.jss.2016.04.032
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DP9XR
UT WOS:000378851700032
PM 27363660
DA 2026-07-24
ER

PT J
AU Lalliss, SJ
   Stinner, DJ
   Waterman, SM
   Branstetter, JG
   Masini, BD
   Wenke, JC
AF Lalliss, Steven J.
   Stinner, Daniel J.
   Waterman, Scott M.
   Branstetter, Joanna G.
   Masini, Brendan D.
   Wenke, Joseph C.
TI Negative Pressure Wound Therapy Reduces Pseudomonas Wound
   Contamination More Than Staphylococcus aureus
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE contamination; infection; open fracture; trauma; negative pressure;
   wound management; acute care
ID VACUUM-ASSISTED CLOSURE
AB Purpose: The purpose of this study is to determine if negative pressure wound therapy (NPWT) treatment results in fewer bacteria than wet-to-dry., (WTD) dressings in a contaminated open fracture wound model
   Methods: For Study Study I. complex wounds were created on the proximal left leg of goats The wounds were inoculated with Pseudomonas aeruginosa The wounds were debrided and irrigated 6 hours after inoculation The first group received WTD dressing chanties twice daily, the second and third groups received NPWT using systems from two different companies All three groups received repeat debridements every 48 hours for 6 days Bacteria quantification was performed both immediately before and after each dabridement For Study 2, the only changes were that Staphylococcus aureus was used and only one NPWT group was included
   Results: In Study I. there were significantly fewer Pseudomonas in both NPWT groups at all imaging sessions after the initial dabridement and irrigation At the 6-day time point. the wounds in the NPWT groups were 43 +/- 14% and 68 +/- 6% of the baseline amount, respectively The WTD groups were 464 +/- 102% of the baseline amount In Study 2, NPWT did not reduce the S aureus contamination within the wound At the 6-day time point, the wounds in the NPWT and WTD groups contained 115 +/- 19% and 192 +/- 52% of the baseline values. respectively
   Conclusion: NPWT showed a significant and sustained decrease in the Pseudomonas levels compared with WTD dressings at all time points This beneficial effect was seen not seen in S aureus
C1 [Lalliss, Steven J.; Stinner, Daniel J.; Waterman, Scott M.; Branstetter, Joanna G.; Masini, Brendan D.; Wenke, Joseph C.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
RP Wenke, JC (通讯作者)，USA, Inst Surg Res, 3400 Rawley E Chambers Ave, Ft Sam Houston, TX 78234 USA.
RI Stinner, Daniel/KSM-9513-2024
OI Stinner, Daniel/0000-0002-8981-6262
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1997, ANN PLAST SURG, V38, P577
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   BODEY GP, 1983, REV INFECT DIS, V5, P279
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Dedmond BT, 2007, J ORTHOP TRAUMA, V21, P11, DOI 10.1097/BOT.0b013e31802cbc54
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Mooney JF, 2000, CLIN ORTHOP RELAT R, P26
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Odland R, 2005, J ORTHOP TRAUMA, V19, P267, DOI 10.1097/01.bot.0000155308.20133.71
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Siragusa GR, 1999, APPL ENVIRON MICROB, V65, P1738
   Svoboda SJ, 2006, J BONE JOINT SURG AM, V88A, P2167, DOI 10.2106/JBJS.E.00248
NR 15
TC 91
Z9 103
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD SEP
PY 2010
VL 24
IS 9
BP 598
EP 602
DI 10.1097/BOT.0b013e3181ec45ba
PG 5
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 647FL
UT WOS:000281603100018
PM 20736802
DA 2026-07-24
ER

PT J
AU Frodl, A
   Geisteuer, N
   Fuchs, A
   Nymark, T
   Schmal, H
AF Frodl, A.
   Geisteuer, N.
   Fuchs, A.
   Nymark, T.
   Schmal, H.
TI Incisional negative pressure wound therapy to reduce surgical-site
   infections in major limb amputations: a meta-analysis
SO EFORT OPEN REVIEWS
LA English
DT Article
DE iNPWT; major amputation; wound therapy
ID VACUUM-ASSISTED CLOSURE; MORTALITY
AB Purpose: Incisional negative pressure wound therapy (iNPWT) has shown effectiveness in the treatment of high-risk surgical wounds. Especially patients with diabetes-induced peripheral arterial disease undergoing major limb amputation have a high intrinsic risk for post-surgical wound infections. While normal gauze wound dressings do not cause stimulation of microvasculature, iNPWT might improve wound healing and reduce wound complications. The purpose of this study was to systematically review the literature for rates of wound complications and readmissions, as well as post-surgical 30-day mortality.
   Methods: We conducted a systematic review searching the Cochrane, PubMed, and Ovid databases. Inclusion criteria were the modified Coleman methodology Score >60, nontraumatic major limb amputation, and adult patients. Traumatic amputations and animal studies were excluded. Relevant articles were reviewed independently by referring to the title and abstract. In a meta-analysis, we compared 3 studies and 457 patients.
   Results: A significantly overall lower rate of postoperative complications is associated with usage of iNPWT (odds ratio (OR) = 0.52; 95% CI: 0.30-0.89; P = 0.02). There was no significant improvement for 30-day mortality, when iNPWT was used (OR= 081; 95% CI: 0.46 - 1.45; P = 0.48). Nevertheless, we did not note a significant difference in the readmission rate or revision surgery between the two groups.
   Conclusion: Overall, the usage of iNPWT may reduce the risk of postoperative wound complications in major lower limb amputations but does not improve 30-day mortality rates significantly. However, to anticipate surgical-site infection, iNPWT has shown effectiveness and thus should be used whenever applicable.
C1 [Frodl, A.; Fuchs, A.; Schmal, H.] Freiburg Univ Hosp, Dept Orthoped & Traumatol, Freiburg, Germany.
   [Geisteuer, N.] Asklepios Hosp Harburg, Dept Orthoped & Traumatol, Hamburg, Germany.
   [Nymark, T.; Schmal, H.] Univ Hosp Odense, Dept Orthoped Surg, Odense C, Denmark.
C3 University of Freiburg; University of Southern Denmark; Odense
   University Hospital
RP Frodl, A (通讯作者)，Freiburg Univ Hosp, Dept Orthoped & Traumatol, Freiburg, Germany.
EM Andreas.Frodl@uniklinik-freiburg.de
RI Schmal, Hagen/B-2684-2016
OI Frodl, Andreas/0000-0002-3899-9345; Nymark, Tine/0000-0002-7474-0701
FU University of Freiburg [DE142116817]; Baden-Wuerttemberg Ministry of
   Science, Research and Art
FX The article processing charge will be funded by the Baden-Wuerttemberg
   Ministry of Science, Research and Art and the University of Freiburg in
   the funding program Open Access Publishing (DE142116817).
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NR 31
TC 9
Z9 12
U1 0
U2 2
PU BIOSCIENTIFICA LTD
PI BRISTOL
PA STARLING HOUSE, 1600 BRISTOL PARKWAY N, BRISTOL, ENGLAND
SN 2396-7544
EI 2058-5241
J9 EFORT OPEN REV
JI EFORT Open Rev.
PD AUG
PY 2022
VL 7
IS 8
BP 526
EP 532
DI 10.1530/EOR-22-0049
PG 7
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 8U2HV
UT WOS:000929772000001
PM 35924636
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Antoniou, GA
   Onwuka, CC
   Antoniou, SA
   Russell, D
AF Antoniou, George A.
   Onwuka, Collins C.
   Antoniou, Stavros A.
   Russell, David
TI Meta-analysis and trial sequential analysis of prophylactic negative
   pressure therapy for groin wounds in vascular surgery
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Review
DE Negative pressure therapy; Vacuum-assisted closure; Surgical site
   infection
ID SURGICAL SITE INFECTION; INCISION; RISK; COMPLICATIONS; PREVENTION
AB Background: Negative pressure therapy has been proposed as a prophylactic measure to promote surgical wound healing and reduce surgical site complications.
   Methods: We conducted a systematic review of the literature to identify randomized controlled trials (RCTs) comparing prophylactic negative pressure therapy with standard practice in closed groin incisions in vascular surgery. We calculated the pooled odds ratio (OR) or risk difference and 95% confidence interval (CI) with the use of the fixed-effect model. To control the risk of type I error, we adjusted the thresholds for the Z-values with the use of the O'Brien-Fleming a-spending function, and the risk of type II error was controlled with the use of the b-spending function and futility boundaries.
   Results: We selected six RCTs reporting on a total of 733 groin wounds. Patients with negative pressure wound therapy had a lower risk of developing surgical site infection (OR, 0.36; 95% CI, 0.24-0.54; P <.001), a lower risk of revision surgery (OR, 0.44; 95% CI, 0.22-0.88; P =.02) and a shorter hospital stay (weighted mean difference, -2.14; 95% CI, -3.78 to 0.49; P =.01). There was no difference in in-hospital mortality (risk difference, 0.01; 95% CI, -0.02 to 0.05; P =.53) or readmission (OR, 0.46; 95% CI, 0.17-1.29; P =.14). The Z-curve for surgical site infection crossed the O'Brien-Fleming significance boundaries for superiority (before the required information size was reached).
   Conclusions: Prophylactic negative pressure wound therapy confers improved outcomes in patients undergoing arterial surgery via a groin incision compared with standard surgical wound care.
C1 [Antoniou, George A.; Onwuka, Collins C.] Pennine Acute Hosp NHS Trust, Royal Oldham Hosp, Dept Vasc & Endovasc Surg, Manchester, Lancs, England.
   [Antoniou, George A.] Univ Manchester, Sch Med Sci, Div Cardiovasc Sci, Manchester, Lancs, England.
   [Antoniou, Stavros A.] European Univ Cyprus, Sch Med, Dept Surg, Nicosia, Cyprus.
   [Russell, David] Leeds Teaching Hosp NHS Trust, Leeds Gen Infirm, Leeds Vasc Inst, Leeds, W Yorkshire, England.
C3 University of Manchester; European University Cyprus; Leeds General
   Infirmary; University of Leeds
RP Antoniou, GA (通讯作者)，Royal Oldham Hosp, Phase 1,Rochdale Rd, Manchester OL1 2JH, Lancs, England.
EM georgios.antoniou@pat.nhs.uk
RI Antoniou, Stavros/I-6844-2019; Russell, David/IXN-3147-2023
OI Russell, David/0000-0002-1293-5618
CR Acosta S, 2017, BJS-BRIT J SURG, V104, pE75, DOI 10.1002/bjs.10403
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NR 21
TC 32
Z9 38
U1 0
U2 1
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
EI 1097-6809
J9 J VASC SURG
JI J. Vasc. Surg.
PD NOV
PY 2019
VL 70
IS 5
BP 1700
EP +
DI 10.1016/j.jvs.2019.01.083
PG 17
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA JH3OV
UT WOS:000492678100043
PM 31126768
OA Bronze
DA 2026-07-24
ER

PT J
AU Hsu, CC
   Chow, SE
   Chen, CPC
   Tsai, WC
   Wang, JS
   Yu, SY
   Lee, SC
AF Hsu, Chih-Chin
   Chow, Shu-Er
   Chen, Carl Pai-Chu
   Tsai, Wen-Chung
   Wang, Jong-Shyan
   Yu, Shin-Ying
   Lee, Sheng-Chi
TI Negative pressure accelerated monolayer keratinocyte healing involves
   Cdc42 mediated cell podia formation
SO JOURNAL OF DERMATOLOGICAL SCIENCE
LA English
DT Article
DE Negative-pressure wound therapy; Wound healing; Cell movement; Actins
ID VACUUM-ASSISTED CLOSURE; ENDOTHELIAL-CELLS; WOUND THERAPY; ACTIN;
   PROLIFERATION; MECHANISMS; VIABILITY; MIGRATION; NETWORKS; DYNAMICS
AB Background: Negative-pressure wound therapy (NPWT) is developed to facilitate wound healing at controlled subatmospheric pressures in modern medicine. Molecular mechanism for this therapy is still undefined.
   Objective: This study highlights the localization and time-course of the cell division control protein 42 (Cdc42) in the cell membrane at ambient pressure (AP) and negative pressures of 75 mmHg (NP75), 125 mmHg (NP125) and 175 mmHg (NP175).
   Methods: The prepared cells were cultured in a negative pressure incubator with the same O-2 and CO2 tensions at the four different pressures. The effective time, complete wound closure time, cell volume, cell viability, and the fluorescence of proliferating cell nuclear antigens (PCNA) and actins were evaluated in cells at different pressures. Wound-healing process and Cdc42 fluorescence were examined in cells with the knockdown of Cdc42. Cdc42 pathway proteins in cell membranes were analyzed after incubation at different pressures for 6 and 12 h.
   Results: The cells at NP125 had less wound closure time and obvious cell podia. Similar PCNA fluorescent intensity was observed in cells at different pressures. The Cdc42, neural Wiskott-Aldrich syndrome protein, and actin expression increased significantly (p < 0.05) in plasma membranes of cells at NP125 for 12 h. The knockdown of active Cdc42 resulted in the absence of Cdc42 expression at the cell leading edge.
   Conclusions: The activation and localization of Cdc42 pathway proteins in the cell membrane are involved in the cell podia formation in keratinocytes at NP125. NPWT may facilitate cell migration to accelerate wound healing. (c) 2013 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.
C1 [Hsu, Chih-Chin; Yu, Shin-Ying; Lee, Sheng-Chi] Chang Gung Mem Hosp, Dept Phys Med & Rehabil, Keelung 20401, Taiwan.
   [Hsu, Chih-Chin; Tsai, Wen-Chung] Chang Gung Univ, Coll Med, Sch Tradit Chinese Med, Tao Yuan, Taiwan.
   [Chow, Shu-Er] Chang Gung Univ, Coll Med, Ctr Gen Studies, Tao Yuan, Taiwan.
   [Chen, Carl Pai-Chu; Tsai, Wen-Chung] Chang Gung Mem Hosp, Dept Phys Med & Rehabil, Tao Yuan, Taiwan.
   [Wang, Jong-Shyan] Chang Gung Univ, Inst Rehabil Sci, Coll Med, Tao Yuan, Taiwan.
C3 Chang Gung Memorial Hospital; Chang Gung University; Chang Gung
   University; Chang Gung Memorial Hospital; Chang Gung University
RP Hsu, CC (通讯作者)，Chang Gung Mem Hosp, Dept Phys Med & Rehabil, 222 Maijin Rd, Keelung 20401, Taiwan.
EM steele0618@gmail.com
OI Wang, Jong-Shyan/0000-0002-3095-9357
FU Chang Gung Memorial Hospital, Keelung [CMRPG290401]
FX We thank the Chang Gung Memorial Hospital, Keelung, for a Grant
   (CMRPG290401) to support this study.
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NR 34
TC 22
Z9 25
U1 0
U2 14
PU ELSEVIER IRELAND LTD
PI CLARE
PA ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000,
   IRELAND
SN 0923-1811
EI 1873-569X
J9 J DERMATOL SCI
JI J. Dermatol. Sci.
PD JUN
PY 2013
VL 70
IS 3
BP 196
EP 203
DI 10.1016/j.jdermsci.2013.03.007
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 160UO
UT WOS:000320146200007
PM 23622765
DA 2026-07-24
ER

PT J
AU Contractor, D
   Amling, J
   Brandoi, C
   Tosi, LL
AF Contractor, Dhruti
   Amling, June
   Brandoi, Cinzia
   Tosi, Laura L.
TI Negative Pressure Wound Therapy With Reticulated Open Cell Foam in
   Children: An Overview
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE NPWT/ROCF; children; pediatric; wound; infection; VAC; VAC Therapy
ID VACUUM-ASSISTED CLOSURE; STERNAL WOUNDS; SUBATMOSPHERIC PRESSURE;
   MANAGEMENT; MEDIASTINITIS; FRACTURES; INFECTION; INJURIES; TRIAL
AB This article summarizes the results of a comprehensive review of the literature on the use of negative pressure wound therapy with reticulated open cell foam (NPWT/ROCF) as delivered by VA.C.(R) Therapy (KCI, San Antonio, TX) in pediatric patients. A review of the literature revealed 20 articles that discussed the use of NPWT/ROCF in exclusively pediatric patients. Nine articles were retrospective reviews, and I I Were Case Studies. This review discusses the insights from these articles. This review discusses the versatility of NPWT/ROCF for use with pediatric patients with infected wounds; full-thickness burns; open fractures large soft tissue wounds; surgical wounds of the chest, abdomen, and spine; pilonidal disease; and pressure ulcers. NPWT/ROCF has been used in children as young as a few weeks of age, and in children with comorbidities such as congenital heart disease, immunosuppression, And spina bifida. Wound heating in children can be delayed by impaired perfusion, infection, edema, and poor nutrition. Clinical considerations for using NPWT/ROCF in children can include differences in healing due to higher granulation rates requiring more frequent dressing changes, poor nutritional status, small size, and low weight. With pediatric patients, there is no consensus on foam (white or black) selection, optimum amount of negative pressure, frequency of NPWT/ROCF dressing changes, and interposing contact layer selection. Randomized prospective Studies are needed to make recommendations for safe and efficacious clinical practice. Research regarding the effects of dressing types, adjunctive treatment, and wound healing in neonates and children is needed.
C1 [Tosi, Laura L.] Childrens Natl Med Ctr, Bone Hlth Program, Washington, DC 20010 USA.
   [Contractor, Dhruti; Tosi, Laura L.] George Washington Univ, Sch Med, Washington, DC USA.
C3 Children's National Health System; George Washington University
RP Tosi, LL (通讯作者)，Childrens Natl Med Ctr, Bone Hlth Program, 111 Michigan Ave,NW, Washington, DC 20010 USA.
EM ltosi@crunc.org
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NR 46
TC 27
Z9 36
U1 0
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD NOV-DEC
PY 2008
VL 22
IS 10
SU S
BP S167
EP S176
DI 10.1097/BOT.0b013e318188e295
PG 10
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 371GP
UT WOS:000260820100009
PM 19034165
DA 2026-07-24
ER

PT J
AU Chen, XQ
   Li, J
   Li, QY
   Zhang, W
   Lei, ZJ
   Qin, DY
   Pan, ZP
   Li, JQ
   Li, XY
AF Chen, Xiaoqiang
   Li, Jing
   Li, Qiaoying
   Zhang, Wei
   Lei, Zhanjun
   Qin, Danying
   Pan, Zeping
   Li, Jinqing
   Li, Xueyong
TI Spatial-Temporal Changes of Mechanical Microenvironment in Skin Wounds
   During Negative Pressure Wound Therapy
SO ACS BIOMATERIALS SCIENCE & ENGINEERING
LA English
DT Article
DE NPWT; mechanical microenvironment; shear wave elastography; finite
   element analysis
ID VACUUM-ASSISTED CLOSURE; IN-VIVO; CELL MORPHOLOGY; TISSUE; STIFFNESS;
   STRAIN; MORPHOGENESIS; MULTICENTER; MIGRATION; HYDROGELS
AB Cell migration, proliferation, and differentiation are regulated by mechanical cues during skin wound healing. Negative pressure wound therapy (NPWT) reduces the healing period by optimizing the mechanical micro environment of the wound bed. Under NPWT, it remains elusive how the mechanical microenvironment (e.g., stiffness, strain gradients) changes both in time and space during wound healing. To illustrate this, the healing time of full thickness skin wounds under NPWT, with pressure settings ranging from -50 to -150 mm Hg, were evaluated and compared with gauze dressing treatments (control group), and three-dimensional finite element models of full-thickness skin wounds on days 1 and 5 after treatment were developed on the basis of MR 3D imaging data. Shear wave elastography (SWE) was applied to detect the stiffness of wound soft tissue on days 1 and 5, and nonlinear finite element analysis (FEA) was used to represent the spatial temporal environment of the 3D strain field of the wound under NPWT vs the control group. Compared with the control group, NPWT with -50, -80, and -125 mm Hg promoted wound healing. SWE showed that the elastic modulus of wounded skin increased during healing. Meanwhile, the elastic modulus in wounded skin under NPWT was significantly smaller than in the control group. Strain and its gradient decreased under NPWT during wound healing, while no significant change was observed in the control group. This study, which is based on MR 3D imaging, shear wave elastography, and nonlinear FEA, provides an in-depth understanding of changes of the skin mechanical microenvironment under NPWT in the time-space dimension and the associated wound healing.
C1 [Chen, Xiaoqiang; Li, Jing; Lei, Zhanjun; Qin, Danying; Pan, Zeping; Li, Jinqing; Li, Xueyong] Fourth Mil Med Univ, Tangdu Hosp, Dept Plast & Burn Surg, 1 Xinsi Rd, Xian 710038, Shaanxi, Peoples R China.
   [Li, Qiaoying] Fourth Mil Med Univ, Tangdu Hosp, Dept Ultrasonog, 1 Xinsi Rd, Xian 710038, Shaanxi, Peoples R China.
   [Zhang, Wei] Fourth Mil Med Univ, Tangdu Hosp, Dept Radiol & Nucl Med, 1 Xinsi Rd, Xian 710038, Shaanxi, Peoples R China.
C3 Air Force Medical University; Air Force Medical University; Air Force
   Medical University
RP Li, JQ; Li, XY (通讯作者)，Fourth Mil Med Univ, Tangdu Hosp, Dept Plast & Burn Surg, 1 Xinsi Rd, Xian 710038, Shaanxi, Peoples R China.
EM lijqfmmu@hotmail.com; lixueyong641123@163.com
RI ; Pan, Zeping/JVZ-2118-2024
OI XIAOQIANG, CHEN/0000-0002-0926-9546; 
FU National Science Foundation of China [81671929, 81272134]; Natural
   Science Foundation of Shaanxi Province [2014JM4128]
FX This study was financially supported by the National Science Foundation
   of China (81671929, 81272134) and the Natural Science Foundation of
   Shaanxi Province (2014JM4128). The authors acknowledge all of their
   colleagues at the Department of Burn and Plastic Surgery, Tangdu
   Hospital, Fourth Military Medical University, for their full cooperation
   and support. The same thanks are also given for the guidance and
   suggestions from Professor Feng Xu and Shaobao Liu, Yuhui Li, and Yufei
   Ma from the Bioinspired Engineering and Biomechanics Center (BEBC),
   Xi'an Jiaotong University.
CR [Anonymous], MEDICINE PHILADELPHI
   [Anonymous], J WOUND CARE S3
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NR 56
TC 18
Z9 20
U1 2
U2 36
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 2373-9878
J9 ACS BIOMATER SCI ENG
JI ACS Biomater. Sci. Eng.
PD APR
PY 2019
VL 5
IS 4
BP 1762
EP 1770
DI 10.1021/acsbiomaterials.8b01554
PG 17
WC Materials Science, Biomaterials
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Materials Science
GA HT0FQ
UT WOS:000464241400011
PM 33405552
DA 2026-07-24
ER

PT J
AU Nolff, MC
   Fehr, M
   Reese, S
   Meyer-Lindenberg, AE
AF Nolff, Mirja Christine
   Fehr, Michael
   Reese, Sven
   Meyer-Lindenberg, Andrea E.
TI Retrospective comparison of negative pressure wound therapy and
   silver-coated foam dressings in open-wound treatment in cats
SO JOURNAL OF FELINE MEDICINE AND SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; SUBATMOSPHERIC PRESSURE; SEPTIC PERITONITIS;
   BLOOD-FLOW; DOGS; MANAGEMENT; SKIN; PROLIFERATION; VIABILITY; BACTERIA
AB Objectives The objective of this study was to evaluate negative pressure wound therapy (NPWT) for the treatment of complicated wounds in cats.
   Methods Twenty cats undergoing open-wound treatment in two clinics were classed according to treatment method: NPWT (group A, n = 10) and polyurethane foam dressing (group B, n = 10). Pairs of patients from each group were matched based on wound conformation, localisation and underlying cause. Cats from both groups were compared in terms of duration of previous treatment, time to closure and complications.
   Results Signalment, duration of previous treatment, antibiotic and antiseptic treatment, and bacterial status were comparable between groups. Total time to wound closure was significantly shorter (P = 0.046, strong effect size; Cohen d = 0.8) in group A (25.8 days, range 11.0-57.0 days) compared with group B (39.5 days, range 28.0-75.0 days). NPWT-treated wounds suffered fewer complications and became septic less frequently during treatment compared with wounds treated with a foam dressing. The progression of fat tissue necrosis was particularly well controlled under NPWT, resulting in fewer deaths due to this condition in this group. However, although a strong effect of NPWT on the progression of infection, fever and sepsis was detected (Cramer-V 0.5), this difference was not significant.
   Conclusions and relevance This study demonstrated that time to healing was considerably shorter, and complication rate lower, in NPWT-treated animals compared with foam dressing-treated cats. In particular, the effective management of infection by NPWT emphasises the value of NPWT in the treatment of cats suffering from infected wounds.
C1 [Nolff, Mirja Christine; Meyer-Lindenberg, Andrea E.] Ludwig Maximilians Univ Munchen, Clin Small Anim Surg & Reprod, Vet Str 13, Munich, Germany.
   [Fehr, Michael] Univ Vet Med Hannover, Small Anim Clin, Hannover, Germany.
   [Reese, Sven] Ludwig Maximilians Univ Munchen, Dept Vet Basic Sci, Munich, Germany.
C3 University of Munich; University of Veterinary Medicine Hannover;
   University of Munich
RP Nolff, MC (通讯作者)，Ludwig Maximilians Univ Munchen, Clin Small Anim Surg & Reprod, Vet Str 13, Munich, Germany.
EM m.nolff@lmu.de
RI Reese, Sven/F-1826-2016; Nolff, Mirja/W-6756-2019; Meyer-Lindenberg,
   Andrea/H-1076-2011
OI Reese, Sven/0000-0002-4605-9791; Nolff, Mirja/0000-0001-9317-7769;
   Meyer-Lindenberg, Andrea/0000-0001-6137-3773
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NR 43
TC 8
Z9 11
U1 3
U2 22
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1098-612X
EI 1532-2750
J9 J FELINE MED SURG
JI J. Feline Med. Surg.
PD JUN
PY 2017
VL 19
IS 6
BP 624
EP 630
DI 10.1177/1098612X16645141
PG 7
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA EV9VX
UT WOS:000402135500009
PM 27102692
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Cahill, C
   Fowler, A
   Williams, LJ
AF Cahill, Caitlin
   Fowler, Amanda
   Williams, Lara J.
TI The application of incisional negative pressure wound therapy for
   perineal wounds: A systematic review
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Review
DE abdominoperineal; colorectal; incisional negative pressure wound
   therapy; VAC
ID EXTRALEVATOR ABDOMINOPERINEAL EXCISION; SURGICAL SITE INFECTIONS;
   PRIMARY CLOSURE; RECTAL-CANCER; MANAGEMENT-SYSTEM; RISK-FACTORS;
   RESECTION; COMPLICATIONS; RECONSTRUCTION; SURGERY
AB Impaired perineal wound healing is a major source of morbidity after abdominoperineal resection. Incisional negative pressure wound therapy can improve healing, prevent infections, and decrease the frequency of dehiscence. Our objective was to summarise existing evidence on the use of incisional negative pressure wound therapy on perineal wounds after abdominoperineal resection and to determine the effect on perineal wound complications. Electronic databases were searched in January 2017. Studies describing the use of incisional negative pressure wound therapy on primarily closed perineal wounds after abdominoperineal resection were included. Of the 278 identified articles, 5 were retrieved for inclusion in the systematic review (n=169 patients). A significant decrease in perineal wound complications when using incisional negative pressure wound therapy was demonstrated, with surgical site infection rates as low as 9% (vs 41% in control groups). The major limitation of this systematic review was a small number of retrieved studies with small patient populations, high heterogeneity, and methodological issues. This review suggests that incisional negative pressure wound therapy decreases perineal wound complications after abdominoperineal resection. Further prospective trials with larger patient populations would be needed to confirm this association and delineate which patients might benefit most from the intervention.
C1 [Cahill, Caitlin; Fowler, Amanda; Williams, Lara J.] Ottawa Hosp, Div Gen Surg, Sect Colorectal & Minimally Invas Surg, Ottawa, ON, Canada.
C3 University of Ottawa; Ottawa Hospital Research Institute
RP Williams, LJ (通讯作者)，Civ Parkdale Clin, 737 Parkdale Ave,3rd Floor, Ottawa, ON K1Y 1J8, Canada.
EM larwilliams@toh.ca
OI Cahill, Caitlin/0000-0003-2705-6074
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NR 43
TC 20
Z9 30
U1 1
U2 11
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2018
VL 15
IS 5
BP 740
EP 748
DI 10.1111/iwj.12921
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA GU0OU
UT WOS:000444951400008
PM 29863305
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Tuncel, U
   Turan, A
   Bayraktar, MA
   Aydin, U
   Erkorkmaz, U
AF Tuncel, Umut
   Turan, Aydin
   Bayraktar, M. Alper
   Aydin, Ufuk
   Erkorkmaz, Unal
TI Clinical Experience With the Use of Gauze-based Negative Pressure Wound
   Therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; TRANSDUCTION; MANAGEMENT; INJURIES; PATIENT;
   IMPACT; FOAM
AB Purpose. In this preliminary study, gauze-based negative pressure wound therapy (NPWT) was used to accelerate granulation tissue formation and promote closure in a number of wound types. The authors aimed to evaluate the efficacy of gauze-based NPWT using the Chariker-Jeter technique for wounds requiring delayed closure. Methods. A retrospective review was conducted of 50 patients with wounds not suitable for immediate primary closure. After initial irrigation, debridement, and antibiotic therapy, Chariker-Jeter technique NPWT was used and dressings were changed at 24- to 48-hour intervals before secondary closure or primary closure. In addition, a 4-point category scoring system (severe, moderate, mild, and none) was used to evaluate pain. Semi-quantitative data also were obtained. Results. Wound size decreased considerably, granulation tissue formation was accelerated, and exudate was reduced and removed by the end of the treatment. The patients were followed for 12 months. Pre- and post-treatment averages of the wound surface areas were 90.21 +/- 74.97 cm(2) and 35.71 +/- 53.63 cm(2), respectively (P < 0.001). Average duration of treatment was 12.98 +/- 3.18 days and average wound size reduction following the treatment was 64.61% +/- 30.42%. Granulation tissue was clinically observed in all wounds by day 5. Six cases healed without any operation; the others required various reconstructive methods to cover the wounds. After surgical intervention, only 3 patients treated with gauze-based NPWT had a recurrence. No infections were observed during the follow-up period. According to the pain form, only 2 patients had severe pain. Conclusion. The gauze-based NPWT was found to be a safe and cost-effective method in temporary soft-tissue management of chronic nonhealing wounds suitable delayed closure.
C1 [Tuncel, Umut] Gaziosmanpasa Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-60100 Tokat, Turkey.
   [Bayraktar, M. Alper] Cekirge State Hosp, Dept Plast Reconstruct & Aesthet Surg, Bursa, Turkey.
   [Aydin, Ufuk] Edirne State Hosp, Dept Plast Reconstruct & Aesthet Surg, Edirne, Turkey.
   [Erkorkmaz, Unal] Gaziosmanpasa Univ, Dept Biostat, TR-60100 Tokat, Turkey.
C3 Tokat Gaziosmanpasa University; Cekirge State Hospital; Edirne State
   Hospital; Tokat Gaziosmanpasa University
RP Tuncel, U (通讯作者)，Gaziosmanpasa Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-60100 Tokat, Turkey.
EM drumuttuncel@gmail.com
RI Turan, Aydın/V-6669-2017; Tuncel, Umut/P-3185-2015; Erkorkmaz,
   Ünal/AAA-4241-2022
OI Turan, Aydın/0000-0002-1540-1443; Tuncel, Umut/0000-0001-5029-2927;
   Erkorkmaz, Ünal/0000-0002-8497-4704
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NR 23
TC 1
Z9 1
U1 0
U2 6
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD AUG
PY 2012
VL 24
IS 8
BP 227
EP 233
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 994EI
UT WOS:000307913300010
PM 25874610
DA 2026-07-24
ER

PT J
AU Hariri, M
   Maaz, B
   Netfagi, M
   Alawa, J
   Sattouf, A
   Dubies, HA
   Alahmad, J
   Seyitisa, MF
   Godier-Furnemont, A
   Ghali, A
   Ghandour, A
   Abdullah, Z
   Alsaleh, M
   Almousa, I
   Habib, W
   Alshaer, H
AF Hariri, Mahmoud
   Maaz, Bakry
   Netfagi, Measser
   Alawa, Jude
   Sattouf, Ahmad
   Dubies, Hussam Alden
   Alahmad, Jehad
   Seyitisa, Muhammet Fuat
   Godier-Furnemont, Amandine
   Ghali, Abedalkarem
   Ghandour, Ahmad
   Abdullah, Zohair
   Alsaleh, Munther
   Almousa, Ibrahim
   Habib, Waiel
   Alshaer, Hisham
TI Validation of a Manual Negative Pressure Wound Therapy Device
   (PragmaVAC) for Acute and Chronic Wounds: A Prospective, Randomized,
   Controlled Trial
SO WORLD JOURNAL OF SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; EVIDENCE-BASED RECOMMENDATIONS; MANAGEMENT;
   STEPS
AB Background Negative pressure wound therapy (NPWT) is an alternative to the standard gauze dressings for wound treatment. Due to limited health resources, poor electrical supply, and high costs, NPWT in resource-constrained settings is inaccessible. In conflict-affected settings, civilian injuries typically involve traumatic wounds or chronic wound infections that affect the extremities.
   Methods PragmaVAC (R) is a manually operated NPWT device designed to increase accessibility to NPWT without the need of electrical power. We aimed to determine the clinical efficacy of PragmaVAC through a controlled, non-blinded open-label clinical trial in a resource-constrained locality. The endpoint was formation of granulation tissue sufficient for wound closure.
   Results Fifty-nine patients qualified for analysis (19 Gauze; 40 PragmaVAC). The mean age of participants was 49.25 years, 55.9% were male, and 42.4% were diabetic. Forty three wounds (72.9%) were acute, 44 wounds (74.6%) were clean-contaminated, and 34 wounds (57.6%) were localized to the lower limb. The average duration of treatment was 15.3 days in PragmaVAC vs 36.5 days in control, p = 0.013. Similarly, PragmaVAC required fewer number of dressing changes 2.7 vs 23.2 times, p < 0.0001, at a lower frequency of dressings 0.22/day vs 0.73/day, in the control group, p < 0.0001.
   Conclusions PragmaVAC is associated with accelerated healing and less frequent requirement of dressing changes. The introduction of a manually operated, low-cost device in resource-constrained settings presents an opportunity to improve wound care outcomes, decrease interventions, and optimize usage of material and human resources.
C1 [Hariri, Mahmoud; Seyitisa, Muhammet Fuat; Alshaer, Hisham] Pragmat Innovat Inc, Mississauga, ON, Canada.
   [Hariri, Mahmoud; Alahmad, Jehad] Syrian Board Med Specialties SBOMS, Gaziantep, Turkey.
   [Maaz, Bakry; Ghali, Abedalkarem; Alsaleh, Munther] Mohamed Waseem Maaz Hosp, Northern Aleppo, Syria.
   [Netfagi, Measser; Ghandour, Ahmad; Abdullah, Zohair] Rahma Darkoush Hosp, Darkoush, Syria.
   [Alawa, Jude] Stanford Univ, Sch Med, Stanford, CA 94305 USA.
   [Dubies, Hussam Alden; Alahmad, Jehad; Almousa, Ibrahim] Idleb Surg Hosp, Idleb, Syria.
   [Godier-Furnemont, Amandine] Univ Calif San Francisco, Dept Surg, San Francisco, CA USA.
   [Sattouf, Ahmad; Habib, Waiel] Idleb Cent Hosp, Idleb, Syria.
C3 Stanford University; University of California System; University of
   California San Francisco
RP Hariri, M (通讯作者)，Pragmat Innovat Inc, Mississauga, ON, Canada.; Hariri, M (通讯作者)，Syrian Board Med Specialties SBOMS, Gaziantep, Turkey.
EM m.hariri@sboms.org
RI ; Alawa, Jude/QJX-2484-2026
OI Godier-Furnemont, Amandine/0000-0002-3613-0881; Alawa,
   Jude/0000-0003-3600-4356; Alshaer, Hisham/0000-0001-6736-2215; 
FU Creating Hope in Conflict: a Humanitarian Grand Challenge; USAID, The UK
   Government; Ministry of Foreign Affairs of the Netherlands; Global
   Affairs Canada; Grand Challenges Canada
FX This project is supported by Creating Hope in Conflict: a Humanitarian
   Grand Challenge; a partnership of USAID, The UK Government, the Ministry
   of Foreign Affairs of the Netherlands, and Global Affairs Canada, with
   support from Grand Challenges Canada.
CR Albayati WK., 2021, PRS-GLOB OPEN, V9, DOI 10.1097/GOX.0000000000003787
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NR 21
TC 2
Z9 3
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD DEC
PY 2022
VL 46
IS 12
BP 2946
EP 2953
DI 10.1007/s00268-022-06713-8
EA SEP 2022
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 5Y1GG
UT WOS:000863173500004
PM 36175648
DA 2026-07-24
ER

PT J
AU Correa, JC
   Mejía, DA
   Duque, N
   Montoya, M
   Uribe, CM
AF Camilo Correa, J.
   Alejandro Mejia, D.
   Duque, N.
   Montoya J, M.
   Morales Uribe, C.
TI Managing the open abdomen: negative pressure closure versus
   mesh-mediated fascial traction closure: a randomized trial
SO HERNIA
LA English
DT Article
DE Open abdomen; Temporary abdominal closure; Negative pressure wound
   therapy; Mesh
ID VACUUM-ASSISTED CLOSURE; TEMPORARY ABDOMINAL CLOSURE; VENTRAL HERNIA;
   MANAGEMENT; TRAUMA; SURGERY; WOUNDS; ASSOCIATION; EXPERIENCE; EVOLUTION
AB To compare the effectiveness of abdominal wall closure using the vacuum-assisted closure (NPC) as described by Barker et al. with an institutional protocol using a double polyvinyl bag in the first surgery, which is changed in subsequent surgeries to a polyvinyl bag placed over the bowel loops and a prolene mesh attached to the abdominal fascia (MMFC).
   Randomized controlled trial. Patients with open abdomen (OA) due to a traumatic or a medical cause were included in the study. Variables studied included demographics, indication for surgery, number of interventions, hospital length of stay (HLOS), ICU length of stay, abdominal wound care costs, complication rates, and method and time to definitive fascial closure.
   From June 2011 to April 2013, 75 patients were enrolled in the study. Patients who died within 48 h were excluded; therefore, 53 patients in total were assessed. NPC achieved fascial closure in 75 % of patients, and MMFC achieved closure in 71.9 % of patients. The closure rates in patients with OA secondary to medical causes (80 % by NPC vs. 71.4 % by MMFC) or traumatic causes (70 % by NPC vs. 73.7 % by MMFC) were similar in both treatment groups. There were no differences between the groups with respect to cause of OA, complications, length of hospital stay, or the length of stay in the intensive care unit.
   MMFC is a method comparable to NPC for the temporary management of OA that results in similar closure and complication rates.
C1 [Camilo Correa, J.; Alejandro Mejia, D.; Montoya J, M.; Morales Uribe, C.] Univ Antioquia, Medellin, Colombia.
   [Duque, N.; Morales Uribe, C.] Hosp Univ San Vicente Fdn, Medellin, Colombia.
C3 Universidad de Antioquia
RP Correa, JC (通讯作者)，Univ Antioquia, Medellin, Colombia.
EM jcccote@yahoo.com; damt23@hotmail.com; nicoduque1960@gmail.com;
   marcelamj11@gmail.com; hernando.morales@udea.edu.co
RI ; Duque-Gardeazabal, Nicolas/OAL-0219-2025
OI Correa-Cote, Juan Camilo/0000-0001-5228-4007; 
CR Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
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   Batacchi S, 2009, CRIT CARE, V13, DOI 10.1186/cc8193
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   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
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   Vargo D, 2009, AM SURGEON, V75, pS1
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
NR 31
TC 16
Z9 22
U1 0
U2 10
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1265-4906
EI 1248-9204
J9 HERNIA
JI Hernia
PD APR
PY 2016
VL 20
IS 2
BP 221
EP 229
DI 10.1007/s10029-016-1459-9
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DG8BD
UT WOS:000372306500005
PM 26833235
DA 2026-07-24
ER

PT J
AU Hu, C
   Zhang, TG
   Ren, B
   Deng, ZM
   Cai, L
   Lei, J
   Ping, AS
AF Hu, Chao
   Zhang, Taogen
   Ren, Bin
   Deng, Zhouming
   Cai, Lin
   Lei, Jun
   Ping, Ansong
TI Effect of Vacuum-Assisted Closure Combined with Open Bone Grafting to
   Promote Rabbit Bone Graft Vascularization
SO MEDICAL SCIENCE MONITOR
LA English
DT Article
DE Bone Regeneration; Bone Transplantation; Negative-Pressure Wound
   Therapy; Transplantation, Homologous
ID PRESSURE WOUND THERAPY; FIBROBLAST GROWTH FACTOR-2; INFECTED TIBIAL
   NONUNION; NEGATIVE-PRESSURE; CHRONIC OSTEOMYELITIS; NON-UNION;
   RECONSTRUCTION; MANAGEMENT; EXCISION; DEFECTS
AB Background: Patients with composite bone non-union and soft tissue defects are difficult to treat. Vacuum-assisted closure (VAC) combined with open bone grafting is one of the most effective treatments at present. The aim of the present study was to preliminarily investigate the effect and mechanism of VAC combined with open bone grafting to promote rabbit bone graft vascularization, and to propose a theoretical basis for clinical work.
   Material/Methods: Twenty-four New Zealand white rabbits were randomly divided into an experimental and a control group. Allogeneic bones were grafted and banded with the proximal femur with a suture. The experimental group had VAC whereas the control group had normal wound closure. The bone vascularization rate was compared based on X-ray imaging, fluorescent bone labeling (labeled tetracycline hydrochloride and calcein), calcium content in the callus, and expression of fibroblast growth factor-2 (FGF-2) in bone allografts by Western blot analysis at the 4th, 8th, and 12th week after surgery.
   Results: At the 4th, 8th, and 12th week after surgery, the results of the tests demonstrated that the callus was larger, contained more calcium (p<0.05), and expressed FGF-2 at higher levels (p<0.05) in the experimental group than in the control group. Fluorescent bone labeling showed the distance between the two fluorescent ribbons was significantly shorter in the control group than in the experimental group at the 8th and 12th week after surgery.
   Conclusions: VAC combined with open bone grafting promoted rabbit bone graft vascularization.
C1 [Hu, Chao; Deng, Zhouming; Cai, Lin; Lei, Jun; Ping, Ansong] Wuhan Univ, Zhongnan Hosp, Dept Orthoped, Wuhan 430072, Hubei, Peoples R China.
   [Zhang, Taogen] People Hosp Daye City, Dept Orthoped, Daye, Hubei, Peoples R China.
   [Ren, Bin] Wuhan Univ, Zhongnan Hosp, Dept Radiochemo Therapy, Wuhan 430072, Hubei, Peoples R China.
C3 Wuhan University; Wuhan University
RP Cai, L (通讯作者)，Wuhan Univ, Zhongnan Hosp, Dept Orthoped, Wuhan 430072, Hubei, Peoples R China.
EM guke3559@aliyun.com
RI Ping, An/GRJ-3145-2022; Li, Caiting/ABD-6818-2021
OI Hu, Chao/0000-0001-9093-2642; 
FU Hubei Provincial Natural Science [2014CFA063]
FX The study was funded by the key grant from Hubei Provincial Natural
   Science (No. 2014CFA063)
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NR 41
TC 12
Z9 14
U1 0
U2 8
PU INT SCIENTIFIC INFORMATION, INC
PI MELVILLE
PA 150 BROADHOLLOW RD, STE 114, MELVILLE, NY 11747 USA
SN 1643-3750
J9 MED SCI MONITOR
JI Med. Sci. Monitor
PD APR 27
PY 2015
VL 21
BP 1200
EP 1206
PG 7
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA CG8DW
UT WOS:000353538400002
PM 25913359
DA 2026-07-24
ER

PT J
AU Szmeja, J
   Borejsza-Wysocki, M
   Bobkiewicz, A
   Krokowicz, L
   Banasiewicz, T
   Szmyt, K
AF Szmeja, Jacek
   Borejsza-Wysocki, Maciej
   Bobkiewicz, Adam
   Krokowicz, Lukasz
   Banasiewicz, Tomasz
   Szmyt, Krzysztof
TI THE COMPARISON OF QUALITY OF LIFE IN PATIENTS WITH PILONIDAL SINUS
   DISEASE. NEGATIVE PRESSURE WOUND THERAPY VERSUS STANDARD WOUND DRESSINGS
   - A RANDOMIZED PILOT STUDY
SO GASTROENTEROLOGY
LA English
DT Meeting Abstract
CT Crohn's and Colitis Congress
CY JAN 23-25, 2020
CL Austin, TX
DE Pilonidal sinus; Dermatology Life Quality Index; Negative Pressure Wound
   Therapy
NR 0
TC 0
Z9 0
U1 0
U2 0
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0016-5085
EI 1528-0012
J9 GASTROENTEROLOGY
JI Gastroenterology
PD MAY
PY 2020
VL 158
IS 6
SU 1
MA Tu2053
BP S1601
EP S1601
PG 1
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Gastroenterology & Hepatology
GA LY2KR
UT WOS:000540349505288
DA 2026-07-24
ER

PT J
AU Maier, J
   Kandulski, A
   Donlon, NE
   Werner, JM
   Mehrl, A
   Mueller, M
   Doenecke, A
   Schlitt, HJ
   Hornung, M
   Weiss, ARR
AF Maier, Jonas
   Kandulski, A.
   Donlon, N. E.
   Werner, J. M.
   Mehrl, A.
   Mueller, M.
   Doenecke, A.
   Schlitt, H. J.
   Hornung, M.
   Weiss, A. R. R.
TI Endoscopic vacuum therapy significantly improves clinical outcomes of
   anastomotic leakages after 2-stage, 3-stage, and transhiatal
   esophagectomies
SO LANGENBECKS ARCHIVES OF SURGERY
LA English
DT Article
DE Endoscopic vacuum therapy; Anastomotic leak; Esophagectomy; Gastric tube
   reconstruction; Endoscopic vacuum-assisted closure therapy; Negative
   pressure wound therapy
ID ASSISTED CLOSURE; TREATMENT OPTIONS; ESOPHAGEAL; STENT
AB BackgroundAnastomotic leakages after esophagectomies continue to constitute significant morbidity and mortality. Intrathoracic anastomoses pose a high risk for mediastinitis, sepsis, and death, if a leak is not addressed timely and appropriately. However, there are no standardized treatment recommendations or algorithms as for how to treat these leakages.MethodsThe study included all patients at the University Hospital Regensburg, who developed an anastomotic leakage after esophagectomy with gastric pull-up reconstruction from 2007 to 2022. Patients receiving conventional treatment options for an anastomotic leakage (stents, drainage tubes, clips, etc.) were compared to patients receiving endoscopic vacuum-assisted closure (eVAC) therapy as their mainstay of treatment. Treatment failure was defined as cervical esophagostomy formation or death.ResultsIn total, 37 patients developed an anastomotic leakage after esophagectomy with a gastric pull-up reconstruction. Twenty patients were included into the non-eVAC cohort, whereas 17 patients were treated with eVAC. Treatment failure was observed in 50% of patients (n = 10) in the non-eVAC cohort and in 6% of patients (n = 1) in the eVAC cohort (p < 0.05). The 90-day mortality in the non-eVAC cohort was 15% (n = 3) compared to 6% (n = 1) in the eVAC cohort. Cervical esophagostomy formation was required in 40% of cases (n = 8) in the non-eVAC cohort, whereas no patient in the eVAC cohort underwent cervical esophagostomy formation.ConclusioneVAC therapy for leaking esophagogastric anastomoses appears to be superior to other treatment strategies as it significantly reduces morbidity and mortality. Therefore, we suggest eVAC as an essential component in the treatment algorithm for anastomotic leakages following esophagectomies, especially in patients with intrathoracic anastomoses.
C1 [Maier, Jonas; Werner, J. M.; Doenecke, A.; Schlitt, H. J.; Hornung, M.; Weiss, A. R. R.] Univ Hosp Regensburg, Dept Surg, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany.
   [Kandulski, A.; Mehrl, A.; Mueller, M.] Univ Hosp Regensburg, Dept Internal Med 1, Gastroenterol Hepatol Endocrinol Rheumatol & Infec, Regensburg, Germany.
   [Donlon, N. E.] Mater Misericordiae Univ Hosp, Dept Surg, Dublin, Ireland.
C3 University of Regensburg; University of Regensburg; Mater Misericordiae
   University Hospital; University College Dublin
RP Weiss, ARR (通讯作者)，Univ Hosp Regensburg, Dept Surg, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany.
EM andi-weiss@outlook.com
RI Weiss, Andreas Robert Rudolf/PIH-6367-2026; Schlitt, Hans/ABG-4368-2020
OI Weiss, Andreas Robert Rudolf/0000-0003-1257-5517; 
FU Projekt DEAL
FX Open Access funding enabled and organized by Projekt DEAL. This research
   received no specific grant from any funding agency in the public,
   commercial, or not-for-profit sectors.
CR Ahrens M, 2010, ENDOSCOPY, V42, P693, DOI 10.1055/s-0030-1255688
   Berlth F, 2019, J GASTROINTEST SURG, V23, P67, DOI 10.1007/s11605-018-4000-x
   Blencowe NS, 2012, ANN SURG, V255, P658, DOI 10.1097/SLA.0b013e3182480a6a
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Chon SH, 2023, SURG ENDOSC, V37, P741, DOI 10.1007/s00464-022-09754-1
   Donlon NE, 2021, IRISH J MED SCI, V190, P297, DOI 10.1007/s11845-020-02321-4
   El-Sourani N, 2022, CLIN ENDOSC, V55, P58, DOI 10.5946/ce.2021.099
   Fabbi M, 2021, DIS ESOPHAGUS, V34, DOI 10.1093/dote/doaa039
   Glatz T, 2017, LANGENBECK ARCH SURG, V402, P323, DOI 10.1007/s00423-017-1550-4
   Gubler C, 2019, DIS ESOPHAGUS, V32, DOI 10.1093/dote/doy126
   Gutschow CA, 2022, LANGENBECK ARCH SURG, V407, P957, DOI 10.1007/s00423-022-02436-5
   Kassis ES, 2013, ANN THORAC SURG, V96, P1919, DOI 10.1016/j.athoracsur.2013.07.119
   Linder G, 2020, SCAND J SURG, V109, P121, DOI 10.1177/1457496919826722
   Mandarino FV, 2022, TECH COLOPROCTOL, V26, P319, DOI 10.1007/s10151-021-02566-w
   Mandarino FV, 2022, ESOPHAGUS-TOKYO, V19, P417, DOI 10.1007/s10388-022-00912-x
   Manghelli JL, 2019, J THORAC DIS, V11, P131, DOI 10.21037/jtd.2018.12.13
   Markar SR, 2020, J CLIN ONCOL, V38, P2130, DOI 10.1200/JCO.19.02483
   Markar SR, 2013, ANN SURG ONCOL, V20, P4274, DOI 10.1245/s10434-013-3189-x
   Mennigen R, 2015, J GASTROINTEST SURG, V19, P1229, DOI 10.1007/s11605-015-2847-7
   Mennigen R, 2014, WORLD J GASTROENTERO, V20, P7767, DOI 10.3748/wjg.v20.i24.7767
   Min YW, 2019, BMC SURG, V19, DOI 10.1186/s12893-019-0497-5
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Müller PC, 2021, ANN SURG, V274, P751, DOI 10.1097/SLA.0000000000005125
   Rausa E, 2018, DIS ESOPHAGUS, V31, DOI 10.1093/dote/doy060
   Schorsch T, 2013, SURG ENDOSC, V27, P2040, DOI 10.1007/s00464-012-2707-4
   Scognamiglio P, 2020, ENDOSCOPY, V52, P632, DOI 10.1055/a-1149-1741
   Sondergaard MMA, 2021, JACC-CARDIOONCOL, V3, P711, DOI 10.1016/j.jaccao.2021.10.002
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   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Weidenhagen R, 2010, ANN THORAC SURG, V90, P1674, DOI 10.1016/j.athoracsur.2010.07.007
NR 32
TC 8
Z9 8
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1435-2443
EI 1435-2451
J9 LANGENBECK ARCH SURG
JI Langenbecks Arch. Surg.
PD FEB 15
PY 2023
VL 408
IS 1
AR 90
DI 10.1007/s00423-023-02826-3
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA A5XT0
UT WOS:000955856700002
PM 36790506
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Le Franc, B
   Sellal, O
   Grimandi, G
   Duteille, F
AF Le Franc, B.
   Sellal, O.
   Grimandi, G.
   Duteille, F.
TI Cost-effectiveness analysis of vacuum-assisted closure in the surgical
   wound bed preparation of soft tissue injuries
SO ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE
LA French
DT Article
DE Vacuum-assisted closure; Cost-effectiveness; Reconstructive surgery;
   Soft tissue injuries; Open fracture
ID MANAGEMENT
AB This work proposes, from the point of view of the University Hospital Center of Nantes (acute care), a cost-effectiveness assessment of negative pressure wound therapy (NPWT), in comparison with moist wound therapy, in the surgical preparation of cutaneous defects requiring reconstructive surgery. This retrospective study was realized after data collection from patient files with hospitalization for the management of open-leg fractures with a view to reconstructive surgery by graft or flap (Cauchoix II or III). Effectiveness criteria, after debridement and NWPT initiation, was the time period required for preparing the wound for definitive reconstructive surgery closure by flap or graft. NWPT is compared, over the same 2000 to 2006 period, to the only existing therapeutic alternative, that is to say moist wound therapy. Only direct costs in relation with consumed resources dedicated to each medical strategy were taken into account. A Mann-Whitney U nonparametric test and boostrap technique have been used for statistical and sensitivity analysis. Twenty-five patients were recruited for the two medical strategies. Wound preparation time is significantly shorter for patient treated with NPWT (p = 0.026 Mann-Whitney U-test) and is equal to 20 days less on average for time period required for preparing the wound for reconstructive surgery. Hospitalization costs is very significantly lower for patients being treated with NPWT (p = 0.02). In absolute value, this cost is reduced on the average by 6000 (sic) per patient (i.e. by more than 60%). The incremental cost-effectiveness ratio is of the order of 164 (sic) per day of wound preparation for surgery gained. (C) 2009 Elsevier Masson SAS. All rights reserved.
C1 [Le Franc, B.; Sellal, O.; Grimandi, G.] CHU Nantes, Hop St Jacques, F-44000 Nantes, France.
   [Duteille, F.] CHU Nantes, Hotel Dieu, Serv Chirurg Plast, F-44000 Nantes, France.
C3 Nantes Universite; CHU de Nantes; Nantes Universite; CHU de Nantes
RP Le Franc, B (通讯作者)，CHU Nantes, Hop St Jacques, 85 Rue St Jacques Arsenal, F-44000 Nantes, France.
EM arz7614@yahoo.fr
RI /A-5380-2015
CR Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Bihariesingh VJ, 2004, ARCH ORTHOP TRAUM SU, V124, P73, DOI 10.1007/s00402-003-0615-8
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   Launois R, 2003, B CANCER, V90, P946
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   Webb Lawrence X, 2002, J Am Acad Orthop Surg, V10, P303
   WORONOFFLEMSI MC, 2000, DOSSIER CNHIM, V21, P40
   RESUME RECOMMANDATIO
   PRESENTATION TABLES
NR 16
TC 9
Z9 14
U1 0
U2 4
PU ELSEVIER
PI BRIDGEWATER
PA 685 ROUTE 202-206, BRIDGEWATER, NJ 08807 USA
SN 0294-1260
EI 1768-319X
J9 ANN CHIR PLAST ESTH
JI Ann. Chir. Plast. Esthet.
PD JUN
PY 2010
VL 55
IS 3
BP 195
EP 203
DI 10.1016/j.anplas.2009.04.001
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 609MR
UT WOS:000278661300004
PM 19640626
DA 2026-07-24
ER

PT J
AU Assirati, G
   Serra, V
   Tarantino, G
   Aldrovandi, S
   Ballarin, R
   Magistri, P
   De Ruvo, N
   Di Benedetto, F
AF Assirati, G.
   Serra, V.
   Tarantino, G.
   Aldrovandi, S.
   Ballarin, R.
   Magistri, P.
   De Ruvo, N.
   Di Benedetto, F.
TI Vacuum-Assisted Closure Therapy in Patients Undergoing Liver
   Transplantation With Necessity to Maintain Open Abdomen
SO TRANSPLANTATION PROCEEDINGS
LA English
DT Article
ID PRESSURE WOUND THERAPY; NEGATIVE-PRESSURE; MANAGEMENT
AB Background. Negative-pressure wound therapy (NPWT) has been recognized as a valid method of temporary abdominal closure. The role of open abdomen (OA) in the management of abdominal sepsis has been a controversial issue. Recent experimental and clinical studies have indicated that vacuum-assisted closure (VAC) is associated with superior outcomes in the treatment of OA conditions, but sufficient proof of efficacy and effectiveness is lacking.
   Methods. We enrolled in this observational study all patients who had undergone liver transplantation (LT) for all causes between 2007 and 2014 in whom we needed to use VAC therapy, describing the pathology that led to the complication, length of hospitalization, graft survival, microbial identifications, and causes of death.
   Results. We enrolled 11 patients-6 men (55%) and 5 women (45%), from 41.92 to 64.96 years old (mean, 57.62 +/- 6.56 years) -who went to LT for different pathologies. The mean hospital stay was 56.72 +/- 36.40 days (range, 8-133 days). Graft survival was 35.65 +/- 31.61 months (range, 1.51-89.19 months). Six of 11 patients died (55%) of different causes; in particular, 4 patients died 1 to 3 months after the procedures that led to the condition of OA for septic shock and subsequent multi-organ failure.
   Conclusions. Complications related to the use of NPWT, such as painful management and bleeding, are rare and mild when the device is used properly. Although studies are needed to verify the real cost/benefit ratio in this application of VAC therapy, we consider it a useful means to treat the OA condition.
C1 [Assirati, G.; Serra, V.; Tarantino, G.; Aldrovandi, S.; Ballarin, R.; Magistri, P.; De Ruvo, N.; Di Benedetto, F.] Univ Modena & Reggio Emilia, Hepatopancreatobiliary Surg & Liver Transplanta, Modena, Italy.
C3 Universita di Modena e Reggio Emilia
RP Di Benedetto, F (通讯作者)，AOU Policlin Modena, Via Pozzo 71, I-41100 Modena, Italy.
EM fabrizio.dibenedetto@unimore.it
RI Tarantino, Giuseppe/AAD-1064-2022; Magistri, Paolo/C-4425-2016; Di
   Benedetto, Fabrizio/B-8388-2015
OI Tarantino, Giuseppe/0000-0001-8102-6293; Magistri,
   Paolo/0000-0001-8326-069X; 
CR Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
   [Anonymous], ICU DIR
   [Anonymous], GASTROENTEROL RES PR
   Ashby RL, 2012, TRIALS, V13, DOI 10.1186/1745-6215-13-119
   Bruhin A, 2014, INT J SURG, V12, P1105, DOI 10.1016/j.ijsu.2014.08.396
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   Kubiak BD, 2010, SHOCK, V34, P525, DOI 10.1097/SHK.0b013e3181e14cd2
   Quyn AJ, 2012, COLORECTAL DIS, V14, pE429, DOI 10.1111/j.1463-1318.2012.03045.x
   Rahmanian-Schwarz A, 2012, BURNS, V38, P573, DOI 10.1016/j.burns.2011.10.010
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   Seidel D, 2013, TRIALS, V14, DOI 10.1186/1745-6215-14-394
   Tsuei BJ, 2004, AM SURGEON, V70, P652
NR 15
TC 9
Z9 10
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0041-1345
EI 1873-2623
J9 TRANSPL P
JI Transplant. Proc.
PD MAR
PY 2016
VL 48
IS 2
BP 383
EP 385
DI 10.1016/j.transproceed.2015.12.037
PG 3
WC Immunology; Surgery; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Immunology; Surgery; Transplantation
GA DK9HA
UT WOS:000375240300024
PM 27109961
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Brennfleck, FW
   Bongards, C
AF Brennfleck, Frank W.
   Bongards, Christine
TI Health economic assessment of negative pressure wound therapy use in the
   management of subcutaneous abdominal wound healing impairment (SAWHI) in
   the out-of-hospital setting
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE cost-benefit analysis; economic model; negative pressure wound therapy;
   wound healing
ID CARE
AB Development of subcutaneous abdominal wound healing impairment (SAWHI) can greatly affect patient care. Complications from SAWHI include delayed healing, increased risk of infection, and fascial dehiscence resulting in increased patient care and associated costs. Treatment options include conventional wound treatment or negative pressure wound therapy, both of which can be used in the out-of-hospital setting. However, limited published evidence on cost-effectiveness exists. A conservative health economic model was created to assess the cost-benefit of negative pressure wound therapy in the out-of-hospital setting for the management of SAWHI. Study data from a published multicentre randomised controlled trial was used and represented 221 patients that received care in the out-of-hospital setting. The mean per-patient total cost within 42 days was slightly higher in the negative pressure wound therapy group (2034.98 euro versus 1918.91 euro); however, when wound closure rates were considered, a cost savings of 4155.98 euro per closed wound was observed with the use of negative pressure wound therapy (4324.34 euro versus 8480.32 euro). A cost-effectiveness analysis was constructed, and negative pressure wound therapy was observed to have a lower cost of care and a higher incremental closure rate.
C1 [Brennfleck, Frank W.] Main Kinzig Kliniken, Dept Gen Visceral & Vasc Surg, Herzbachweg 14, D-63571 Gelnhausen, Germany.
   [Bongards, Christine] 3M Deutschland GmbH, 3M, Global Hlth Econ & Outomes Res, Neuss, Germany.
C3 3M
RP Brennfleck, FW (通讯作者)，Main Kinzig Kliniken, Dept Gen Visceral & Vasc Surg, Herzbachweg 14, D-63571 Gelnhausen, Germany.
EM frank.brennfleck@ukr.de
RI Brennfleck, Frank/GOV-6490-2022
OI Brennfleck, Frank/0000-0001-8055-9282
CR [Anonymous], 2022, LAUER-TAXE®- reliable pharmaceutical information for all drugs and contracts registered in Germany
   [Anonymous], 2022, FEE SCHEDULE DOCTORS
   [Anonymous], PERSONNEL COSTS
   [Anonymous], DOCTARI MAGAZIN
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   Dowsett C, 2012, INT WOUND J, V9, P544, DOI 10.1111/j.1742-481X.2011.00913.x
   Sandy-Hodgetts Kylie, 2015, Int Wound J, V12, P265, DOI 10.1111/iwj.12088
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   Seidel D, 2020, JAMA SURG, V155, P469, DOI 10.1001/jamasurg.2020.0414
   Sellmer, PRICE INFORM MODERN
   Wegener, NURSE SALARY WHAT NU
NR 12
TC 6
Z9 6
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD FEB
PY 2023
VL 20
IS 2
BP 458
EP 466
DI 10.1111/iwj.13894
EA JUL 2022
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 8K9TL
UT WOS:000824399700001
PM 35833308
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Echebiri, NC
   McDoom, MM
   Aalto, MM
   Fauntleroy, J
   Nagappan, N
   Barnabei, VM
AF Echebiri, Nelson C.
   McDoom, M. Maya
   Aalto, Meaghan M.
   Fauntleroy, Jessie
   Nagappan, Nagammai
   Barnabei, Vanessa M.
TI Prophylactic Use of Negative Pressure Wound Therapy After Cesarean
   Delivery
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Article
ID SURGICAL SITE INFECTION; MEDICAL DECISION-ANALYSIS; RISK-FACTORS;
   POSTDISCHARGE SURVEILLANCE; LAPAROTOMY INCISIONS; SECTION; PRIMER;
   VACUUM; PREVENTION; MANAGEMENT
AB OBJECTIVE: To evaluate the economic benefit of prophylactic negative pressure wound therapy on a closed laparotomy incision after cesarean delivery in comparison with standard postoperative dressing.
   METHODS: We designed a decision-analytic model from a third-party payer's perspective to determine the cost-benefit of prophylactic application of negative pressure wound therapy compared with standard postoperative dressing on a closed laparotomy incision after cesarean delivery. Our primary outcome measure was the expected value of the cost per strategy. Baseline probabilities and cost assumptions were derived from published literature. We conducted sensitivity analyses using both deterministic and probabilistic models. Cost estimates reflect 2014 U. S. dollars.
   RESULTS: Under our baseline parameters, standard postoperative dressing was the preferred strategy. Standard postoperative dressing and prophylactic negative pressure wound therapy cost $547 and $804 per strategy, respectively. Sensitivity analyses showed that prophylactic negative pressure wound therapy can be cost-beneficial if it is priced below $192; standard postoperative dressing is the preferred strategy among patients with surgical site infection rate of 14% or less. If surgical site infection rates are greater than 14%, prophylactic negative pressure wound therapy could be cost-beneficial depending on the degree of reduction in surgical site infections. At a surgical site infection rate of 30%, the rate must be reduced by 15% for negative pressure wound therapy to become the preferred strategy. Monte Carlo simulation of 1,000 patients in 1 million trials showed that standard postoperative dressing was the preferred cost-beneficial strategy with a frequency of 85%.
   CONCLUSION: Our cost-benefit analysis provides economic evidence suggesting that negative pressure wound therapy should not be used on closed laparotomy incisions of patients with low risk of postcesarean delivery surgical site infections. However, among patients with a high risk of surgical site infections, prophylactic negative pressure wound therapy is potentially cost-beneficial.
C1 SUNY Buffalo, Dept Obstet & Gynecol, Buffalo, NY 14221 USA.
   Mississippi State Univ, Social Sci Res Ctr, Starkville, MS USA.
   Harvard Univ, Sch Publ Hlth, Dept Global Hlth & Populat, Boston, MA 02115 USA.
C3 State University of New York (SUNY) System; University at Buffalo, SUNY;
   Mississippi State University; Harvard University; Harvard T.H. Chan
   School of Public Health
RP Echebiri, NC (通讯作者)，SUNY Buffalo, Dept Obstet Gynecol, 219 Bryant St, Buffalo, NY 14221 USA.
EM nelsonechebiri@gmail.com
OI Barnabei, Vanessa/0000-0002-9650-0143
CR Alanis MC, 2010, AM J OBSTET GYNECOL, V203
   American College of Obstetricians and Gynecologists, 2013, Obstet Gynecol, V121, P213, DOI 10.1097/01.aog.0000425667.10377.60
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NR 41
TC 38
Z9 42
U1 0
U2 8
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0029-7844
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD FEB
PY 2015
VL 125
IS 2
BP 299
EP 307
DI 10.1097/AOG.0000000000000634
PG 9
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA CA0GR
UT WOS:000348595500004
PM 25569006
DA 2026-07-24
ER

PT J
AU Spychala, A
   Murawa, D
   Nowaczyk, P
   Polom, K
AF Spychala, Arkadiusz
   Murawa, Dawid
   Nowaczyk, Piotr
   Polom, Karol
TI Use of vacuum-assisted closure in treatment of intestinal fistula-case
   report
SO WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY
LA Polish
DT Article
DE intestinal fistula; vacuum-assisted closure
ID ENTEROCUTANEOUS FISTULAS; WOUND CONTROL; MANAGEMENT; EXPERIENCE
AB Intestinal fistulae are severe complications of gastrointestinal tract operations. Vacuum-assisted closure is one method to treat them. VAC promotes wound heating by increased blood flow through the wound, faster granulation, removal of excess wound fluid and decrease in bacterial colonization. Nowadays the method is commonly used in treatment of stomach compartment syndrome, infected wounds, leg ulceration, as supportive therapy in skin grafting and burn wounds. Another application of the device is intestinal fistula. The aim of the report is case presentation of a patient with intestinal fistula successfully treated by vacuum-assisted closure.
C1 [Spychala, Arkadiusz; Murawa, Dawid; Nowaczyk, Piotr; Polom, Karol] Wielkopolskie Ctr Onkol, Oddzial Chirurg Onkol & Ogolnej 1, PL-61866 Poznan, Poland.
C3 Wielkopolskie Centrum Onkologii
RP Spychala, A (通讯作者)，Wielkopolskie Ctr Onkol, Oddzial Chirurg Onkol & Ogolnej 1, Ul Garbary 15, PL-61866 Poznan, Poland.
EM a_spychala@wp.pl
RI Nowaczyk, Piotr/AAO-5213-2020; Polom, Karol/ABI-6795-2020
OI Nowaczyk, Piotr/0000-0002-6605-7646; Polom, Karol/0000-0003-2011-4155
CR Alvarez AA, 2001, GYNECOL ONCOL, V80, P413, DOI 10.1006/gyno.2000.6092
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NR 12
TC 0
Z9 0
U1 0
U2 1
PU TERMEDIA PUBLISHING HOUSE LTD
PI POZNAN
PA WENEDOW ST 9-1, POZNAN, 61-614, POLAND
SN 1428-2526
J9 WSPOLCZESNA ONKOL
JI Wspolczesna Onkol.
PY 2008
VL 12
IS 10
BP 461
EP 464
PG 4
WC Oncology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology
GA 445UB
UT WOS:000266075900006
DA 2026-07-24
ER

PT J
AU White, RA
   Miki, RA
   Kazmier, P
   Anglen, JO
AF White, RA
   Miki, RA
   Kazmier, P
   Anglen, JO
TI Vacuum-assisted closure complicated by erosion and hemorrhage of the
   anterior tibial artery
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE vacuum-assisted; erosion; hemorrhage; fracture; artery
ID SECURING SKIN-GRAFTS; NEGATIVE-PRESSURE; SUBATMOSPHERIC PRESSURE;
   RELIABLE METHOD; WOUND CONTROL; THERAPY; EXPERIENCE; DEVICE; TRAUMA;
   SYSTEM
AB We report an erosion and hemorrhage of a left anterior tibial artery associated with a vacuum-assisted closure device. To our knowledge, this report represents the first arterial erosion associated with a vacuum-assisted closure device. We estimate our patient lost 6 units of blood. The hemorrhage was complicated by anticoagulation and a traumatic setting. Based on our complication, we believe great care should be taken when placing a vacuum-assisted closure device adjacent to an exposed artery.
C1 Boone Orthopaed Associates, Columbia, MO 65201 USA.
   Univ Missouri, Univ Hosp, Dept Orthopaed Surg, Columbia, MO USA.
C3 University of Missouri System; University of Missouri Columbia
RP Anglen, JO (通讯作者)，Boone Orthopaed Associates, Broadway Med Plaza,1601 E Broadway,Suite 300, Columbia, MO 65201 USA.
EM anglenj@health.missouri.edu
OI Anglen, Jeffrey/0000-0001-9910-6611
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NR 29
TC 59
Z9 91
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD JAN
PY 2005
VL 19
IS 1
BP 56
EP 59
DI 10.1097/00005131-200501000-00011
PG 4
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 888TR
UT WOS:000226397600011
PM 15668586
DA 2026-07-24
ER

PT J
AU Liao, EC
   Breuing, KH
AF Liao, Eric C.
   Breuing, Karl H.
TI Breast mound salvage using vacuum-assisted closure device as bridge to
   reconstruction with inferolateral AlloDerm hammock
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE breast reconstruction; implant infection; hematoma; acellular dermal
   matrix; AlloDerm; vacuum-assisted closure device; VAC
ID WOUND THERAPY; INFECTIONS; IMPLANTS
C1 Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, Boston, MA 02115 USA.
C3 Harvard University; Harvard Medical School; Harvard University Medical
   Affiliates; Brigham & Women's Hospital
RP Breuing, KH (通讯作者)，Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
EM kbreuing@partners.org
OI Liao, Eric/0000-0001-6385-7448
CR Armstrong DG, 2004, WOUNDS, P9
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   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
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NR 18
TC 16
Z9 18
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD AUG
PY 2007
VL 59
IS 2
BP 218
EP 224
DI 10.1097/SAP.0b013e31802c148c
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 194SF
UT WOS:000248363400019
PM 17667419
DA 2026-07-24
ER

PT J
AU Delarestaghi, MM
   Ahmadi, A
   Firouzabadi, FD
   Roomiani, M
   Firouzabadi, MD
   Faham, Z
AF Delarestaghi, Mojtaba Maleki
   Ahmadi, Aslan
   Firouzabadi, Fatemeh Dehghani
   Roomiani, Maryam
   Firouzabadi, Mohammad Dehghani
   Faham, Zhaleh
TI Effect of Low-Pressure Drainage Suction on Pharyngocutaneous Fistula
   After Total Laryngectomy
SO ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
LA English
DT Article
DE surgical procedures; operative; drainage; negative-pressure wound
   therapy; pharyngocutaneous fistula
ID VACUUM-ASSISTED CLOSURE; RISK-FACTORS; MULTIVARIATE-ANALYSIS; SALVAGE
   LARYNGECTOMY; PRIMARY RADIOTHERAPY; PREDISPOSING FACTORS; WOUND THERAPY;
   METAANALYSIS; HEAD
AB Objective: Pharyngocutaneous fistula (PCF) is one of the most severe multifactorial complications following laryngectomy. The current study aimed at determining the effect of a low-pressure vacuum drain on the incidence of PCF after total laryngectomy. Methods: The current randomized clinical trial was conducted on 35 patients undergoing total laryngectomy in Hazrat Rasoul Akram and Firoozgar hospitals in Tehran, Iran. The subjects were divided into the vacuum drain (n = 15) and control (without vacuum drain) (n = 20) groups. The incidence of PCF and the recovery time were recorded. Results: The rate of PCF formation from the stoma and wound edges was significantly lower in the low-pressure vacuum drain group than in the control group (6.7% vs 40%) (P < .05). There was no significant difference between the groups in time to recovery from PCF. Conclusion: The low-pressure vacuum drain method is effective in reducing the incidence of PCF after total laryngectomy.
C1 [Delarestaghi, Mojtaba Maleki] Iran Univ Med Sci, Firoozgar Hosp, Five Senses Inst, Otolaryngol,ENT & Head & Neck Res Ctr & Dept, Tehran, Iran.
   [Ahmadi, Aslan] Iran Univ Med Sci, ENT & Head & Neck Res Ctr & Dept, Otolaryngol, Tehran, Iran.
   [Firouzabadi, Fatemeh Dehghani; Roomiani, Maryam; Firouzabadi, Mohammad Dehghani; Faham, Zhaleh] Iran Univ Med Sci, ENT & Head & Neck Res Ctr & Dept, Tehran, Iran.
C3 Iran University of Medical Sciences; Iran University of Medical
   Sciences; Iran University of Medical Sciences
RP Roomiani, M; Faham, Z (通讯作者)，Iran Univ Med Sci, ENT & Head & Neck Res Ctr & Dept, Tehran, Iran.
EM maryamroomiani3@gmail.com; zhalehfaham@gmail.com
RI ; Ahmadi, Aslan/P-6152-2018
OI Maleki Delarestaghi, Mojtaba/0000-0002-9703-2425; Dehghani Firouzabadi,
   Fatemeh/0000-0002-2665-3910; 
CR Aarts MCJ, 2011, OTOLARYNG HEAD NECK, V144, P5, DOI 10.1177/0194599810390914
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NR 30
TC 7
Z9 8
U1 0
U2 7
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0003-4894
EI 1943-572X
J9 ANN OTO RHINOL LARYN
JI Ann. Otol. Rhinol. Laryngol.
PD JAN
PY 2021
VL 130
IS 1
BP 32
EP 37
AR 0003489420934506
DI 10.1177/0003489420934506
EA JUN 2020
PG 6
WC Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology
GA PG7KF
UT WOS:000545805600001
PM 32597686
DA 2026-07-24
ER

PT J
AU Chiummariello, S
   Del Torto, G
   Iera, M
   Arleo, S
   Alfano, C
AF Chiummariello, Stefano
   Del Torto, Giuseppe
   Iera, Marco
   Arleo, Sergio
   Alfano, Carmine
TI Negative Pressure Dressing in Split-Thickness Skin Grafts: Experience
   With an Alternative Method
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE negative pressure skin graft; wound closure
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED CONTROLLED-TRIAL; WOUND THERAPY;
   SUBATMOSPHERIC PRESSURE
AB Background. The use of negative pressure in the dressing of split-thickness skin grafts has been shown to promote healing by a variety of mechanisms, including a decrease in interstitial edema, an increase in perfusion, and a decrease in bacterial colonization. Methods. An observational study was performed on 52 patients at the Department of Plastic Surgery, University of Perugia in Perugia, Italy, undergoing split-thickness skin grafting for acute wounds after trauma and for chronic wounds, such as pressure ulcers and diabetic wounds. The dressing used consisted of a single foam Sheet, a conventional disposable closed-system suction drain, and an adhesive dressing. Results. In all patients, there was a 95% take of the graft, with 5% of partial loss. There were no significant complications encountered. Conclusions. Negative pressure wound therapy is an innovative and commercially successful concept for the management of difficult-to-treat wounds of nearly every etiology, and the authors' technique is an alternative to commercially available negative pressure dressings.
C1 [Chiummariello, Stefano; Del Torto, Giuseppe; Iera, Marco; Arleo, Sergio; Alfano, Carmine] Univ Perugia, Div Plast Reconstruct & Aesthet Surg, I-06100 Perugia, Italy.
C3 University of Perugia
RP Del Torto, G (通讯作者)，Via Ruggero Torelli 8, I-06123 Perugia, Italy.
EM g.deltorto@yahoo.it
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   Preston G, 2008, NURS STAND, V23, P66
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NR 23
TC 10
Z9 12
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD NOV
PY 2013
VL 25
IS 11
BP 324
EP 327
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 259XG
UT WOS:000327559000006
PM 25867632
DA 2026-07-24
ER

PT J
AU Spindler, N
   Lehmann, S
   Steinau, HU
   Mohr, FW
   Langer, S
AF Spindler, N.
   Lehmann, S.
   Steinau, H. -U.
   Mohr, F. -W.
   Langer, S.
TI Complication management after interventions on thoracic organs. Deep
   sternal wound infections
SO CHIRURG
LA German
DT Article
DE Median sternotomy; Sternal osteomyelitis; Mediastinitis; Wound
   debridement; Muscle flaps
ID VACUUM-ASSISTED CLOSURE; SURGERY; MEDIASTINITIS
AB With an incidence rate of 0.5-4 % and a mortality of up to 50 %, deep sternal wound infections are a rare but devastating complication after median sternotomy for cardiac surgery. Currently, no standard operating procedures exist. Long-term drainage with continuous lavage or negative pressure wound therapy should be used to condition the wound. After restabilization of the sternum and primary closure, the infection often reoccurs presenting deep cavities with an open, unstable thorax and an uncovered mediastinum. This article gives an overview of the different options for deep sternal wound infections in plastic reconstructive surgery. The key point for successful treatment is still the extent of debridement. Primary coverage with a pedicled flap can be made only if the wound debridement was performed radically enough. In the clinic of the author, in which over 120 patients with deep sternal wound infections were treated in 2.5 years, latissimus dorsi muscle flaps have been established as the gold standard.
C1 [Spindler, N.; Langer, S.] Univ Klin Orthopadie Unfallchirurg & Plast Chirur, Abt Plast Asthet & Spezielle Handchirurg, D-04103 Leipzig, Germany.
   [Lehmann, S.; Mohr, F. -W.] Univ Klin Leipzig, Herzzentrum Leipzig GmbH, Helios Klin, Leipzig, Germany.
   [Steinau, H. -U.] Univ Klinikum Essen, Klin Unfallchirurg, Essen, Germany.
C3 Helios Kliniken; Heart Center Leipzig GMBH; Leipzig University;
   University of Duisburg Essen
RP Spindler, N (通讯作者)，Univ Klin Orthopadie Unfallchirurg & Plast Chirur, Abt Plast Asthet & Spezielle Handchirurg, Liebigstr 20, D-04103 Leipzig, Germany.
EM nick.spindler@medizin.uni-leipzig.de
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NR 10
TC 17
Z9 22
U1 0
U2 4
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0009-4722
EI 1433-0385
J9 CHIRURG
JI Chirurg
PD MAR
PY 2015
VL 86
IS 3
BP 228
EP 233
DI 10.1007/s00104-014-2833-8
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CE1WL
UT WOS:000351603500004
PM 25693778
DA 2026-07-24
ER

PT J
AU Orgill, DP
   Austen, WG
   Butler, CE
   Fine, NA
   Horvath, KA
   Mihaljevic, T
   Song, DH
   Wolfe, WG
AF Orgill, DP
   Austen, WG
   Butler, CE
   Fine, NA
   Horvath, KA
   Mihaljevic, T
   Song, DH
   Wolfe, WG
TI Guidelines for treatment of complex chest wounds with negative pressure
   wound pressure wound therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; OPEN-HEART-SURGERY; ARTERY-BYPASS-SURGERY;
   CARDIAC SURGICAL-PROCEDURES; MODIFIED ELOESSER FLAP; RAT
   SKELETAL-MUSCLE; RISK-FACTORS; MEDIAN STERNOTOMY; GRAFT-SURGERY;
   POSTSTERNOTOMY MEDIASTINITIS
AB Complex chest wounds front trauma, infection, tumor, and post-surgical complications provide challenges to sui-cons because of the vital structures within the thorax. Median sternotomy is the most common cause of complex chest wounds. An expert panel of cardiac and plastic surgeons reviewed the medical literature oil complex chest wounds using an evidence-based approach. Negative pressure wound therapy (NPWT) is an increasingly common modality to treat complex chest wounds. Evidence to date demonstrates that NPWT is a safe and effective modality for treating complex chest wounds. Reports indicate that NPWT removes wound exudates, stimulates granulation tissue formation, and reduces the number of dressing changes. In general, NPWT is used as a bridge to surgical closure but. is occasionally used as a primary wound treatment. Further studies are needed to better understand the mechanism of action, optimize utilization protocols, and demonstrate the cost effectiveness of this new technology.
RI Orgill, Dennis/H-7596-2019
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NR 130
TC 10
Z9 33
U1 0
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD DEC
PY 2004
SU B
BP 1
EP 23
PG 23
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 885FO
UT WOS:000226142700001
DA 2026-07-24
ER

PT J
AU Kim, DY
   Park, SJ
   Bang, SI
   Mun, GH
   Pyon, JK
AF Kim, Dae Young
   Park, Sun-June
   Bang, Sa-Ik
   Mun, Goo-Hyun
   Pyon, Jai-Kyong
TI Does the Use of Incisional Negative-Pressure Wound Therapy Prevent
   Mastectomy Flap Necrosis in Immediate Expander-Based Breast
   Reconstruction?
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID ACELLULAR DERMAL MATRIX; TISSUE EXPANDER; SPARING MASTECTOMY; SURGICAL
   INCISIONS; HIGH-RISK; COMPLICATIONS; SKIN; METAANALYSIS; EXPERIENCE;
   MANAGEMENT
AB Background: Mastectomy flap necrosis is one of the most common and significant complications in immediate expander-based breast reconstruction. Negative-pressure wound therapy is widely used for open wounds but is not commonly used for closed incisional wounds. However, the postoperative use of incisional negative-pressure wound therapy is demonstrated to reduce complication rates. The authors evaluate the incidence of mastectomy flap necrosis in patients with incisional negative-pressure wound therapy after immediate expander-based breast reconstruction compared with the incidence in patients with conventional dressing.
   Methods: A retrospective review was conducted to identify patients who underwent immediate expander-based breast reconstruction between January of 2010 and February of 2015 at a single institution. Patients were divided into a conventional dressing group and an incisional negative-pressure wound therapy group. Patient demographics, intraoperative findings, and complications were compared between the two groups.
   Results: A total of 228 breasts (206 patients) were included in this study. Of these, the incisional negative-pressure wound therapy group included 45 breasts (44 patients) and the conventional dressing group included 183 breasts (162 patients). The incisional negative-pressure wound therapy group had a lower overall complication rate (11.1 percent versus 27.9 percent; p = 0.019), overall mastectomy flap necrosis rate (8.9 percent versus 23.5 percent; p = 0.030), and major mastectomy flap necrosis rate (2.2 percent versus 13.7 percent; p = 0.031) compared with the conventional dressing group.
   Conclusions: Incisional negative-pressure wound therapy reduced the incidence of mastectomy flap necrosis. This simple and reliable dressing technique can be effective in preventing mastectomy flap necrosis in immediate expander-based breast reconstruction.
C1 [Pyon, Jai-Kyong] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Plast Surg, 81 Irwon Ro, Seoul 135710, South Korea.
C3 Sungkyunkwan University (SKKU); Samsung Medical Center
RP Pyon, JK (通讯作者)，Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Plast Surg, 81 Irwon Ro, Seoul 135710, South Korea.
EM pspriest.pyon@samsung.com
RI Mun, Goo-Hyun/I-2540-2019
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   Ho G, 2012, ANN PLAS SURG, V68, P346, DOI 10.1097/SAP.0b013e31823f3cd9
   Horch RE, 2015, J WOUND CARE, V24, P21, DOI 10.12968/jowc.2015.24.Sup4b.21
   Hultman CS, 2003, ANN PLAS SURG, V50, P249, DOI 10.1097/01.SAP.0000046784.70583.E1
   Ibrahim AMS, 2013, PLAST RECONSTR SURG, V132, P1057, DOI 10.1097/PRS.0b013e3182a3beec
   Ingargiola Michael J, 2013, Eplasty, V13, pe49
   Kanuri A, 2014, PLAST RECONSTR SURG, V133, p448E, DOI 10.1097/PRS.0000000000000025
   Khansa I, 2014, PLAST RECONSTR SURG, V134, P11, DOI 10.1097/PRS.0000000000000261
   Kim JYS, 2012, PLAST RECONSTR SURG, V129, P28, DOI 10.1097/PRS.0b013e3182361fd6
   Lee JH, 2014, ARCH PLAST SURG-APS, V41, P258, DOI 10.5999/aps.2014.41.3.258
   Lee KT, 2013, J PLAST RECONSTR AES, V66, P1543, DOI 10.1016/j.bjps.2013.06.032
   Liu DZ, 2014, ANN PLAS SURG, V72, P503, DOI 10.1097/SAP.0b013e318268a87c
   Mlodinow AS, 2014, J PLAST SURG HAND SU, V48, P322, DOI 10.3109/2000656X.2014.884973
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   MYERS MB, 1971, ANN SURG, V173, P920, DOI 10.1097/00000658-197106010-00009
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Patel Ketan M, 2012, Ann Plast Surg, V69, P139, DOI 10.1097/SAP.0b013e3182250e23
   Phillips BT, 2012, PLAST RECONSTR SURG, V129, p778E, DOI 10.1097/PRS.0b013e31824a2ae8
   Robertson SA, 2014, BRIT J SURG, V101, P899, DOI 10.1002/bjs.9470
   Rozen WM, 2009, CLIN BREAST CANCER, V9, P145, DOI 10.3816/CBC.2009.n.024
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   Tsoi B, 2014, J AM COLL SURGEONS, V218, P1038, DOI 10.1016/j.jamcollsurg.2014.02.011
   Weichman KE, 2015, PLAST RECONSTR SURG, V135, p9E, DOI 10.1097/PRS.0000000000000810
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
NR 39
TC 50
Z9 54
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD SEP
PY 2016
VL 138
IS 3
BP 558
EP 566
DI 10.1097/PRS.0000000000002431
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DZ7BH
UT WOS:000386017900054
PM 27556600
DA 2026-07-24
ER

PT J
AU Hyldig, N
   Vinter, CA
   Kruse, M
   Mogensen, O
   Bille, C
   Sorensen, JA
   Lamont, RF
   Wu, C
   Heidemann, L
   Ibsen, M
   Laursen, J
   Ovesen, P
   Rorbye, C
   Tanvig, M
   Joergensen, J
AF Hyldig, N.
   Vinter, C. A.
   Kruse, M.
   Mogensen, O.
   Bille, C.
   Sorensen, J. A.
   Lamont, R. F.
   Wu, C.
   Heidemann, L. N.
   Ibsen, M. H.
   Laursen, J. B.
   Ovesen, P. G.
   Rorbye, C.
   Tanvig, M.
   Joergensen, J. S.
TI Prophylactic incisional negative pressure wound therapy reduces the risk
   of surgical site infection after caesarean section in obese women: a
   pragmatic randomised clinical trial
SO BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
LA English
DT Article
DE Caesarean section; incisional negative pressure wound therapy; obesity;
   surgical site infection
ID CDC DEFINITIONS; MANAGEMENT; EQ-5D-3L
AB Objective To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth by caesarean section. Design Multicentre randomised controlled trial. Setting Five hospitals in Denmark. Population Obese women (prepregnancy body mass index (BMI) >= 30 kg/m(2)) undergoing elective or emergency caesarean section. Method The participants were randomly assigned to incisional negative pressure wound therapy or a standard dressing after caesarean section and analysed by intention-to-treat. Blinding was not possible due to the nature of the intervention. Main outcome measures The primary outcome was surgical site infection requiring antibiotic treatment within the first 30 days after surgery. Secondary outcomes included wound exudate, dehiscence and health-related quality of life. Results Incisional negative pressure wound therapy was applied to 432 women and 444 women had a standard dressing. Demographics were similar between groups. Surgical site infection occurred in 20 (4.6%) women treated with incisional negative pressure wound therapy and in 41 (9.2%) women treated with a standard dressing (relative risk 0.50, 95% CI 0.30-0.84; number needed to treat 22; P = 0.007). The effect remained statistically significant when adjusted for BMI and other potential risk factors. Incisional negative pressure wound therapy significantly reduced wound exudate whereas no difference was found for dehiscence and quality of life between the two groups. Conclusion Prophylactic use of incisional negative pressure wound therapy reduced the risk of surgical site infection in obese women giving birth by caesarean section.
C1 [Hyldig, N.; Bille, C.; Sorensen, J. A.; Heidemann, L. N.] Univ Southern Denmark, Inst Clin Res, Odense Univ Hosp, Dept Plast Surg, JB Winslowsvej 4,Entrance 20,1st Floor, DK-5000 Odense C, Denmark.
   [Hyldig, N.; Vinter, C. A.; Lamont, R. F.; Wu, C.; Tanvig, M.; Joergensen, J. S.] Univ Southern Denmark, Inst Clin Res, Odense Univ Hosp, Dept Gynaecol & Obstet, Odense, Denmark.
   [Hyldig, N.] Odense Univ Hosp, OPEN Odense Patient Data Explorat Network, Odense, Denmark.
   [Kruse, M.] Univ Southern Denmark, Inst Publ Hlth, Danish Ctr Hlth Econ DaCHE, Odense, Denmark.
   [Mogensen, O.] Karolinska Univ Hosp, Dept Pelv Canc, Stockholm, Sweden.
   [Mogensen, O.] Karolinska Inst, Stockholm, Sweden.
   [Lamont, R. F.] UCL, Northwick Pk Inst Med Res Campus, Div Surg, London, England.
   [Heidemann, L. N.; Tanvig, M.] Lillebaelt Hosp, Dept Gynaecol & Obstet, Kolding, Denmark.
   [Ibsen, M. H.] Hosp Southern Jutland, Dept Gynaecol & Obstet, Esbjerg, Denmark.
   [Laursen, J. B.; Rorbye, C.] Univ Copenhagen, Hvidovre Hosp, Dept Gynaecol & Obstet, Hvidovre, Denmark.
   [Ovesen, P. G.] Aarhus Univ Hosp, Dept Gynaecol & Obstet, Aarhus, Denmark.
C3 University of Southern Denmark; Odense University Hospital; University
   of Southern Denmark; Odense University Hospital; University of Southern
   Denmark; Odense University Hospital; University of Southern Denmark;
   Karolinska Institutet; Karolinska University Hospital; Karolinska
   Institutet; University of London; University College London; University
   of Copenhagen; Aarhus University
RP Hyldig, N (通讯作者)，Univ Southern Denmark, Inst Clin Res, Odense Univ Hosp, Dept Plast Surg, JB Winslowsvej 4,Entrance 20,1st Floor, DK-5000 Odense C, Denmark.
EM nana.hyldig@rsyd.dk
RI Sørensen, Jens Ahm/D-6279-2014; Mogensen, Ole/Q-1894-2015; Hyldig,
   Nana/AAH-5220-2020
OI Sørensen, Jens Ahm/0000-0003-4903-0094; Vinter, Christina
   Anne/0000-0001-5084-6053; Mogensen, Ole/0000-0001-7655-9909; Hyldig,
   Nana/0000-0001-6758-6294
FU University of Southern Denmark; Odense University Hospital; Region of
   Southern Denmark; Lundbeckfonden; iNPWT device manufacturer Smith
   Nephew; Novo Nordisk Fonden [NNF15OC0014596] Funding Source:
   researchfish; Steno Diabetes Center Aarhus (SDCA) [506] Funding Source:
   researchfish; Steno Diabetes Center Odense (SDCO) [SDCO Research 002]
   Funding Source: researchfish
FX Funding for this peer-reviewed, investigator-initiated clinical trial
   was provided by grants from the University of Southern Denmark, Odense
   University Hospital, the Region of Southern Denmark, Lundbeckfonden, and
   an unrestricted grant from the iNPWT device manufacturer Smith & Nephew
   (devices and operating funding). None of these sources of funds had an
   influence on study design, data collection, data analyses,
   interpretation of results or writing of the report.
CR Allen DB, 1997, ARCH SURG-CHICAGO, V132, P991
   [Anonymous], 2016, Global Guidelines for the Prevention of Surgical Site Infection
   [Anonymous], SURG SIT INF PREV TR
   [Anonymous], DATA RESOURCE PROFIL
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NR 33
TC 74
Z9 87
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1470-0328
EI 1471-0528
J9 BJOG-INT J OBSTET GY
JI BJOG
PD APR
PY 2019
VL 126
IS 5
BP 628
EP 635
DI 10.1111/1471-0528.15413
PG 8
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA HN7AY
UT WOS:000460341700016
PM 30066454
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Becker, R
   Szöke, N
   Gottstein, J
AF Becker, R
   Szöke, N
   Gottstein, J
TI Wound management of the deep wound infection after complex dorsoventral
   spinal column fusion L3 to S1 under application of the vacuum assisted
   closure
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nuernberg, GERMANY
DE vacuum assisted closure; dorsoventral spondylodesis; wound management;
   ambulant vacuum therapy; patient compliance
C1 Eduardus Krankenhaus Koln Deutz, Orthopad Klin, D-50679 Cologne, Germany.
RP Becker, R (通讯作者)，Eduardus Krankenhaus Koln Deutz, Orthopad Klin, Custodisstr 3-17, D-50679 Cologne, Germany.
EM dr_rolf.becker@arcor.de
NR 0
TC 2
Z9 2
U1 0
U2 0
PU JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
PI STUTTGART
PA RUEDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S93
EP S95
DI 10.1055/s-2006-921456
PG 3
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 034DB
UT WOS:000236904100021
PM 16575654
DA 2026-07-24
ER

PT J
AU Javed, AA
   Teinor, J
   Wright, M
   Ding, D
   Burkhart, RA
   Hundt, J
   Cameron, JL
   Makary, MA
   He, J
   Eckhauser, FE
   Wolfgang, CL
   Weiss, MJ
AF Javed, Ammar A.
   Teinor, Jonathan
   Wright, Michael
   Ding, Ding
   Burkhart, Richard A.
   Hundt, John
   Cameron, John L.
   Makary, Martin A.
   He, Jin
   Eckhauser, Frederic E.
   Wolfgang, Christopher L.
   Weiss, Matthew J.
TI Negative Pressure Wound Therapy for Surgical-site Infections A
   Randomized Trial
SO ANNALS OF SURGERY
LA English
DT Article
DE negative pressure wound therapy; pancreaticoduodenectomy; randomized
   controlled trial; surgical-site infections
ID HOSPITAL COSTS; COMPLICATIONS; PREDICTORS; SURGERY
AB Objective: This study seeks to evaluate the efficacy of negative pressure wound therapy for surgical-site infection (SSI) after open pancreaticoduodenectomy.
   Background: Despite improvement in infection control, SSIs remain a common cause of morbidity after abdominal surgery. SSI has been associated with an increased risk of reoperation, prolonged hospitalization, readmission, and higher costs. Recent retrospective studies have suggested that the use of negative pressure wound therapy can potentially prevent this complication.
   Methods: We conducted a single-center randomized, controlled trial evaluating surgical incision closure during pancreaticoduodenectomy using negative pressure wound therapy in patients at high risk for SSI. We randomly assigned patients to receive negative pressure wound therapy or a standard wound closure. The primary end point of the study was the occurrence of a postoperative SSI. We evaluated the economic impact of the intervention.
   Results: From January 2017 through February 2018, we randomized 123 patients at the time of closure of the surgical incision. SSI occurred in 9.7% (6/62) of patients in the negative pressure wound therapy group and in 31.1% (19/61) of patients in the standard closure group (relative risk = 0.31; 95% confidence interval, 0.13-0.73; P = 0.003). This corresponded to a relative risk reduction of 68.8%. SSIs were found to independently increase the cost of hospitalization by 23.8%.
   Conclusions: The use of negative pressure wound therapy resulted in a significantly lower risk of SSIs. Incorporating this intervention in surgical practice can help reduce a complication that significantly increases patient harm and healthcare costs.
C1 [Javed, Ammar A.; Teinor, Jonathan; Wright, Michael; Ding, Ding; Burkhart, Richard A.; Cameron, John L.; Makary, Martin A.; He, Jin; Eckhauser, Frederic E.; Wolfgang, Christopher L.; Weiss, Matthew J.] Johns Hopkins Univ Hosp, John L Cameron Div Hepatobiliary & Pancreat Surg, Baltimore, MD 21287 USA.
   [Javed, Ammar A.; Teinor, Jonathan; Wright, Michael; Ding, Ding; Burkhart, Richard A.; Hundt, John; Cameron, John L.; Makary, Martin A.; He, Jin; Eckhauser, Frederic E.; Wolfgang, Christopher L.; Weiss, Matthew J.] Johns Hopkins Univ Hosp, Dept Surg, Baltimore, MD 21287 USA.
C3 Johns Hopkins University; Johns Hopkins Medicine; Johns Hopkins
   University; Johns Hopkins Medicine
RP Weiss, MJ (通讯作者)，Johns Hopkins Univ Hosp, 600 N Wolfe St,Blalock 685, Baltimore, MD 21287 USA.
EM mweiss5@jhmi.edu
RI ; Ding, Ding/AAB-3538-2021; Javed, Ammar/AAE-2870-2020; Wolfgang,
   Christopher/HGD-0863-2022
OI He, Jin/0000-0001-9149-2247; Hundt, John/0009-0006-2468-5632; Javed,
   Ammar/0000-0002-5463-5250; 
FU KCI/Acelity [125164]
FX KCI/Acelity (Grant number #125164).
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   [Anonymous], 2004, HOSP EPIDEMIOL INFEC
   [Anonymous], ANN SURG
   Badia JM, 2017, J HOSP INFECT, V96, P1, DOI 10.1016/j.jhin.2017.03.004
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   Blumberg TJ, 2018, SPINE J, V18, P300, DOI 10.1016/j.spinee.2017.07.173
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   Fadayomi AB, 2018, HPB, V20, P658, DOI 10.1016/j.hpb.2018.01.008
   Fong ZV, 2016, JAMA SURG, V151, P432, DOI 10.1001/jamasurg.2015.4510
   Gupta R, 2017, AM SURGEON, V83, P1166
   Javed AA, 2015, INDIAN J SURG, V77, P409, DOI 10.1007/s12262-015-1366-9
   Kelsey JenniferL., 1996, METHODS OBSERVATIONA
   Li PY, 2017, SCAND J SURG, V106, P189, DOI 10.1177/1457496916668681
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   Sayyed R, 2016, JCPSP-J COLL PHYSICI, V26, pS24
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NR 29
TC 95
Z9 105
U1 2
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0003-4932
EI 1528-1140
J9 ANN SURG
JI Ann. Surg.
PD JUN
PY 2019
VL 269
IS 6
BP 1034
EP 1040
DI 10.1097/SLA.0000000000003056
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA IQ4OM
UT WOS:000480730100015
PM 31082899
DA 2026-07-24
ER

PT J
AU Freeman, JJ
   Storto, DLP
   Berry-Cabán, CS
AF Freeman, Julie J.
   Storto, Dominic L. P.
   Berry-Caban, Cristobal S.
TI Repair of a Vesicocutaneous Fistula Using Negative-Pressure Wound
   Therapy and Urinary Diversion via a Nephrostomy Tube
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Bladder; Fistula; Negative pressure wound therapy; Vesicocutaneous
   fistula
AB BACKGROUND: This article describes an unusual case of a vesicocutaneous fistula in a patient with a history of radiation therapy and recent abdominal surgery.
   CASE: A 61-year-old woman was transferred to our acute care facility from a rehabilitation facility, with poor nutritional intake and a concern for urine draining from her wound. A nephrostomy tube was placed (she had only 1 functioning kidney) and negative-pressure wound therapy was used to close the fistula.
   CONCLUSION: Urinary diversion via a nephrostomy tube and negative-pressure wound therapy were used to successfully and safely close this vesicocutaneous fistula.
C1 [Freeman, Julie J.] Womack Army Med Ctr, Dept Nursing, Ft Bragg, NC USA.
   [Storto, Dominic L. P.] Womack Army Med Ctr, Dept Surg, Ft Bragg, NC USA.
   [Berry-Caban, Cristobal S.] Womack Army Med Ctr, Dept Res, Ft Bragg, NC USA.
C3 United States Department of Defense; United States Army; United States
   Department of Defense; United States Army; United States Department of
   Defense; United States Army
RP Freeman, JJ (通讯作者)，2209 Goldentree Way, Vienna, VA 22182 USA.
EM Julie.jacob.freeman@gmail.com
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NR 17
TC 4
Z9 5
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD SEP-OCT
PY 2013
VL 40
IS 5
BP 536
EP 538
DI 10.1097/WON.0b013e3182a46549
PG 3
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 300KA
UT WOS:000330461600014
PM 24448623
DA 2026-07-24
ER

PT J
AU Gomoll, AH
   Lin, A
   Harris, MB
AF Gomoll, Andreas H.
   Lin, Albert
   Harris, Mitchel B.
TI Incisional vacuum-assisted closure therapy
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE vacuum-assisted closure; wound dressing; surgical wound infection
ID SKIN-GRAFTS; BLOOD-FLOW; SURGERY; DEVICE
AB Postoperative swelling and prolonged drainage from surgical incisions result in both practical and medical burdens, such as increased need for dressing changes and potentially higher rates of surgical wound infection. This article presents a technique to apply a vacuum-assisted closure therapy sponge as a postoperative dressing to provide a clean, dry wound environment in the immediate postoperative period.
C1 Brigham & Womens Hosp, Dept Orthoped Surg, Partners Orthoped Trauma, Boston, MA 02115 USA.
   Brigham & Womens Hosp, Dept Orthoped Trauma, Partners Orthoped Trauma, Boston, MA 02115 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard University; Harvard University Medical
   Affiliates; Brigham & Women's Hospital
RP Harris, MB (通讯作者)，Brigham & Womens Hosp, Dept Orthoped Surg, Partners Orthoped Trauma, 75 Francis St, Boston, MA 02115 USA.
EM mbharris@partners.org
RI Lin, Albert/GXH-3277-2022
CR Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Caniano DA, 2005, J PEDIATR SURG, V40, P128, DOI 10.1016/j.jpedsurg.2004.09.016
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NR 14
TC 119
Z9 140
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0890-5339
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD NOV-DEC
PY 2006
VL 20
IS 10
BP 705
EP 709
DI 10.1097/01.bot.0000211159.98239.d2
PG 5
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 110FH
UT WOS:000242363200009
PM 17106382
DA 2026-07-24
ER

PT J
AU Mouës, CM
   Vos, MC
   Van den Bemd, GJCM
   Stijnen, T
   Hovius, SER
AF Mouës, CM
   Vos, MC
   Van den Bemd, GJCM
   Stijnen, T
   Hovius, SER
TI Bacterial load in relation to vacuum-assisted closure wound therapy: A
   prospective randomized trial
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID TEMPORARY ABDOMINAL CLOSURE; MATRIX-METALLOPROTEINASES; SUBATMOSPHERIC
   PRESSURE; STAPHYLOCOCCUS-AUREUS; 7-YEAR EXPERIENCE; NEGATIVE-PRESSURE;
   PACK TECHNIQUE; VENOUS ULCERS; LEG ULCERS; INFECTION
AB Vacuum-assisted closure has become a new technique in the challenging management of contaminated, acute, and chronic wounds. Although promising clinical results have been described, scientific proof to substantiate the mechanism of action of this therapy is scarce. In the present study, we examined whether the positive effect on wound healing found in vacuum-assisted closure-treated wounds could be explained by an effect on the bacterial load. Fifty-four patients who needed open wound management before surgical closure were included in this study. Wounds were randomized to either vacuum-assisted closure therapy (n= 29) or treatment by conventional moist gauze therapy (n= 25). Healing was characterized by development of a clean granulating wound bed ("ready for surgical therapy") and reduction of wound surface area. To quantify bacterial load, biopsies were collected. No significant difference was found in time needed to reach "ready for surgical therapy" comparing both therapies. Wound surface area reduction was significantly larger in vacuum-assisted closure-treated wounds: 3.8 +/- 0.5 percent/day (mean +/- SEM) compared to conventional-treated wounds (1.7 +/- 0.6 percent/day; p < 0.05). The total quantitative bacterial load was generally stable in both therapies. However, nonfermentative gram negative bacilli showed a significant decrease in vacuum-assisted closure-treated wounds (p < 0.05), whereas Staphylococcus aureus showed a significant increase in vacuum-assisted closure-treated wounds (p < 0.05). In conclusion, this study shows a positive effect of vacuum-assisted closure therapy on wound healing, expressed as a significant reduction of wound surface area. However, this could not be explained by a significant quantitative reduction of the bacterial load.
C1 Erasmus MC, Dept Plast & Reconstruct Surg, NL-3000 DR Rotterdam, Netherlands.
   Erasmus MC, Dept Med Microbiol & Infect Dis, NL-3000 DR Rotterdam, Netherlands.
   Erasmus MC, Dept Epidemiol & Biostat, NL-3000 DR Rotterdam, Netherlands.
C3 Erasmus University Rotterdam; Erasmus MC; Erasmus University Rotterdam;
   Erasmus MC; Erasmus University Rotterdam; Erasmus MC
RP Mouës, CM (通讯作者)，Erasmus MC, Dept Plast & Reconstruct Surg, POB 1738, NL-3000 DR Rotterdam, Netherlands.
EM c.moues@erasmusmc.nl
RI vos, margreet/AFF-9452-2022
OI vos, margreet/0000-0002-0496-7038
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NR 51
TC 402
Z9 481
U1 0
U2 42
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JAN
PY 2004
VL 12
IS 1
BP 11
EP 17
DI 10.1111/j.1067-1927.2004.12105.x
PG 7
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 776WX
UT WOS:000189143300003
PM 14974959
DA 2026-07-24
ER

PT J
AU Duda, M
   Kim, P
AF Duda, Marcus
   Kim, Paul
TI Negative Pressure Wound Therapy With Instillation-Dwell in Orthopaedic
   Trauma: How to Avoid Leaks and Frustration
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE negative pressure wound therapy with instillation and dwell; negative
   pressure wound therapy; adhesive; acrylic drapes; foam dressing;
   silicone drapes; hydrophilic dressing
ID SALINE; ADHESIVE
AB Negative pressure wound therapy with instillation-dwell (NPWTi-d) is the natural evolution of NPWT. This therapy combines the benefits of instillation with negative pressure. Advancements in the drape and the foam dressing has further advanced the utility of this therapy for use in orthopaedic trauma wounds. The technique for drape application plays an important role in maximizing the benefits of NPWTi-d. This article provides tips and guidance to ensure a proper dressing seal and other helpful instructions to maximize the benefits of NPWTi-d.
C1 [Duda, Marcus] Cone Hlth Med Grp, OrthoCare, 1211 Virginia St, Greensboro, NC 27401 USA.
   [Kim, Paul] Univ Texas Southwestern, Dept Plast Surg, Dallas, TX USA.
   [Kim, Paul] Univ Texas Southwestern, Dept Orthoped Surg, Dallas, TX USA.
C3 University of Texas System; University of Texas Southwestern Medical
   Center; University of Texas System; University of Texas Southwestern
   Medical Center
RP Duda, M (通讯作者)，Cone Hlth Med Grp, OrthoCare, 1211 Virginia St, Greensboro, NC 27401 USA.
EM mduda@mac.com
OI DUDA, MARCUS/0000-0003-1179-1090; , Paul/0000-0002-6186-6890
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   Fernández LG, 2020, WOUNDS, V32, P279
   Fernández LG, 2020, INT WOUND J, V17, P1829, DOI 10.1111/iwj.13471
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   Kim PJ, 2018, WOUNDS, pS1
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   Kim PJ, 2013, PLAST RECONSTR SURG, V132, P1569, DOI 10.1097/PRS.0b013e3182a80586
   Kim PJ, 2015, Wounds, V27, pS2
   Kimawi AA, 2017, WOUNDS, V29, P46
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   Willy C, 2017, UNFALLCHIRURG, V120, P549, DOI 10.1007/s00113-017-0375-5
NR 19
TC 1
Z9 1
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD SEP
PY 2022
VL 36
SU 4
BP S17
EP S21
DI 10.1097/BOT.0000000000002432
PG 5
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 3Y2NF
UT WOS:000843564400005
PM 35994304
DA 2026-07-24
ER

PT J
AU Hu, CW
   Chang, TNJ
   Chen, YC
   Hu, CH
AF Hu, Ching-Wei
   Chang, Tommy Nai-Jen
   Chen, Yi-Chieh
   Hu, Ching-Hsuan
TI Negative-Pressure Wound Therapy Application in Fingertip Replantations
   and a Systematic Review
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article; Proceedings Paper
CT Plastic Surgery The Meeting / Annual Meeting of the
   American-Society-of-Plastic-Surgeons (ASPS)
CY OCT 06-10, 2017
CL Orlando, FL
SP Amer Soc Plast Surg
ID VENOUS ANASTOMOSIS; FREE-FLAP; ARTERIOVENOUS ANASTOMOSIS; CONGESTION;
   DRAINAGE; SURVIVAL; ARTERY; SALVAGE
AB Background: Fingertip replantation is technically challenging. Venous congestion is one of the most common causes of replantation failure. Therefore, various venous drainage procedures and salvage techniques have been used in venous congestion. Negative-pressure wound therapy has proven beneficial in limb injuries, yet limited studies of fingertip replantation exist. This study aims to analyze risk factors in fingertip replantation and to evaluate the feasibility and clinical benefits of negative-pressure wound therapy compared with other salvage techniques.
   Methods: From January of 2015 to December of 2019, 27 patients (27 digits) who experienced fingertip amputation over Tamai zone I or II underwent replantation. Salvage negative-pressure wound therapy was applied for venous congestion postoperatively. Replantation data were collected for further analysis.
   Results: The overall survival rate of digit replantation with salvage negative-pressure wound therapy was 92.6 percent (25 of 27). The blood transfusion rate was 11.1 percent (three of 27). The average hospitalization time was 8.04 +/- 1.43 days and the median duration of negative-pressure wound therapy was 6 days (range, 4 to 8 days; interquartile range, 2 days). There is no significant difference between the survival and failure groups for all risk factors evaluated.
   Conclusion: Negative-pressure wound therapy is a simple and effective salvage option to relieve venous congestion in fingertip replantation with a satisfactory survival rate, low blood transfusion rate, and short inpatient stay.
C1 Chang Gung Univ, Chang Gung Mem Hosp, Chang Gung Med Coll, Dept Plast & Reconstruct Surg, Taoyuan, Taiwan.
   Chang Gung Univ, Taoyuan, Taiwan.
   Chicing Plast Surg Clin, Taipei, Taiwan.
C3 Chang Gung Memorial Hospital; Chang Gung University; Chang Gung
   University
RP Hu, CH (通讯作者)，Chang Gung Mem Hosp, Dept Plast & Reconstruct Surg, 5 Fuxing St, Taoyuan 333, Taiwan.
EM chinghsuanhu@hotmail.com.tw
CR Aksoy A, 2017, ANN PLAS SURG, V78, P62, DOI 10.1097/SAP.0000000000000793
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   Vaienti L, 2013, J ORTHOP TRAUMATOL, V14, P213, DOI 10.1007/s10195-013-0236-0
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NR 38
TC 6
Z9 7
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JAN
PY 2022
VL 149
IS 1
BP 38E
EP 47E
DI 10.1097/PRS.0000000000008628
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA XS4GV
UT WOS:000732870600010
PM 34936614
DA 2026-07-24
ER

PT J
AU Peng, NR
   Peng, XZ
AF Peng, Nanru
   Peng, Xinzhi
TI Comments on "The impact of negative pressure wound therapy on epidermal
   stem cells and keratinocyte growth factor in deep dermal burn injury: An
   experimental study"
SO BURNS
LA English
DT Letter
DE Negative pressure wound therapy; Wound healing; Epidermal stem cells;
   Keratinocyte; Growth factor; Pig model
C1 [Peng, Nanru] Zhengzhou Univ, Zhengzhou Cent Hosp, 134 Wenhuagong South Rd, Zhengzhou, Henan, Peoples R China.
   [Peng, Xinzhi] Beijing Univ Chinese Med, Grad Sch, 11 North Third Ring East Rd, Beijing, Peoples R China.
C3 Zhengzhou University; Beijing University of Chinese Medicine
RP Peng, NR (通讯作者)，Zhengzhou Univ, Zhengzhou Cent Hosp, 134 Wenhuagong South Rd, Zhengzhou, Henan, Peoples R China.
EM docpeng1998@126.com; 371093437@qq.com
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   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
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   Seswandhana MR, 2025, BURNS, V51, DOI 10.1016/j.burns.2025.107719
   Soares E, 2018, CELL MOL LIFE SCI, V75, P1179, DOI 10.1007/s00018-017-2701-z
   Zou XY, 2025, WOUND REPAIR REGEN, V33, DOI 10.1111/wrr.70032
NR 9
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0305-4179
EI 1879-1409
J9 BURNS
JI Burns
PD FEB
PY 2026
VL 52
IS 1
AR 107757
DI 10.1016/j.burns.2025.107757
EA NOV 2025
PG 2
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA M6452
UT WOS:001630778500015
PM 41297234
DA 2026-07-24
ER

PT J
AU Kim, PJ
   Lookess, S
   Bongards, C
   Griffin, LP
   Gabriel, A
AF Kim, Paul J.
   Lookess, Siobhan
   Bongards, Christine
   Griffin, Leah Passmore
   Gabriel, Allen
TI Economic model to estimate cost of negative pressure wound therapy with
   instillation vs control therapies for hospitalised patients in the
   United States, Germany, and United Kingdom
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE cost-savings; debridement; infection; wound; wound closure techniques;
   wound healing
ID ANTISEPTIC SOLUTION; SALINE; DEBRIDEMENT; STANDARD; IMPACT
AB An economic model was developed to estimate the cost of negative pressure wound therapy with instillation and dwelling of a topical wound solution vs control therapies. Economic model inputs were means derived from the results of a recently published systematic review and meta-analysis of 13 comparative studies of negative pressure wound therapy with instillation. Means across studies comprising complex acute and chronic wounds for negative pressure wound therapy-instillation vs control (negative pressure wound therapy without instillation, gauze dressings, or gentamicin polymethylmethacrylate beads) groups were 1.77 vs 2.69 operating room visits (P = .008) and 9.88 vs 21.80 therapy days (P = .02), respectively. These inputs plus hospital cost data were used to model costs for the United States, Germany, and the United Kingdom. For the United States, Germany, and United Kingdom, respectively, economic model estimates of total potential per patient savings were $33 338, euro8467, and 5626 pound for negative pressure wound therapy-instillation group vs control, based on assumed number of OR visits during therapy, cost of therapy system, and length of therapy. Model results showed an overall potential cost-savings with negative pressure wound therapy-instillation vs control, based on fewer OR visits and shorter therapy duration as reported in the published systematic review and meta-analysis.
C1 [Kim, Paul J.] Univ Texas Southwestern Med Ctr Dallas, Dept Plast Surg, 1801 Inwood Rd, Dallas, TX 75390 USA.
   [Lookess, Siobhan; Bongards, Christine; Griffin, Leah Passmore] 3M, San Antonio, TX USA.
   [Gabriel, Allen] Loma Linda Univ, Med Ctr, Dept Plast Surg, Loma Linda, CA USA.
C3 University of Texas System; University of Texas Southwestern Medical
   Center; 3M; Loma Linda University
RP Kim, PJ (通讯作者)，Univ Texas Southwestern Med Ctr Dallas, Dept Plast Surg, 1801 Inwood Rd, Dallas, TX 75390 USA.
EM paul.kim@utsouthwestern.edu
RI ; Gabriel, Allen/AFK-3548-2022
OI , Paul/0000-0002-6186-6890; 
CR Ali Mazen, 2020, Wounds, V32, pE110
   Ali M, 2020, WOUNDS, V32, P375
   [Anonymous], 2020, KOSTENNACHWEIS KRANK
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   [Anonymous], 2021, HEALTHCARE HEADS
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   [Anonymous], 2021, HOSP KEY DAT HOSP PA
   Association AH, HOSP ADJ EXP PER INP
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   Fernández L, 2019, WOUNDS, V31, pE1
   Gabriel A., 2014, Eplasty, V14
   Gabriel A, 2021, PLAST RECONSTR SURG, V147, p68S, DOI 10.1097/PRS.0000000000007614
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   Lessing C, 2011, WOUNDS, V23, P309
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NR 35
TC 12
Z9 13
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAY
PY 2022
VL 19
IS 4
BP 888
EP 894
DI 10.1111/iwj.13689
EA SEP 2021
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 0N6FB
UT WOS:000702161800001
PM 34582113
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Schaffzin, DM
   Douglas, JM
   Stahl, TJ
   Smith, LE
AF Schaffzin, DM
   Douglas, JM
   Stahl, TJ
   Smith, LE
TI Vacuum-assisted closure of complex perineal wounds
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article; Proceedings Paper
CT Annual Meeting of the American-Society-of-Colon-and-Rectal-Surgeons
CY JUN 21-26, 2003
CL NEW ORLEANS, LA
SP Amer Soc Colon & Rectal Surg
DE wound healing; negative pressure dressing; perineal wounds; surgical
   technique
ID SYSTEM; DEVICE
AB The Vacuum-assisted Closure device decreases the time to wound healing, thus increasing the deposition of granulation tissue, and decreasing the use of wound care specialists. Perineal wounds present a special challenge. We present four cases of complex perineal wounds in which the Vacuum-assisted Closure device was used. In each case, wound care was simplified and healing accelerated. The Vacuum-assisted Closure device allows earlier wound closure, early skin grafting (with improved graft adherence), earlier hospital discharge, and earlier return to baseline functional status. its use in the perineum presents a challenge, but with proper application, even the most complex perineal wounds can be healed.
C1 Washington Hosp Ctr, Sect Colon & Rectal Surg, Washington, DC 20010 USA.
C3 MedStar Washington Hospital Center
RP Schaffzin, DM (通讯作者)，714 Chanticleer, Cherry Hill, NJ 08003 USA.
EM fap5q@yahoo.com
CR Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
   Fabian TS, 2000, AM SURGEON, V66, P1136
   Greer S E, 1999, J Wound Ostomy Continence Nurs, V26, P250
   HANLON M, 2001, JWOCN, V28, P171
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NR 10
TC 42
Z9 54
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD OCT
PY 2004
VL 47
IS 10
BP 1745
EP 1748
DI 10.1007/s10350-004-0633-9
PG 4
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Gastroenterology & Hepatology; Surgery
GA 860JD
UT WOS:000224337600030
PM 15540310
DA 2026-07-24
ER

PT J
AU Gerszberg, KS
   Tan, V
AF Gerszberg, Kenneth S.
   Tan, Virak
TI Vacuum-Assisted Closure With External Fixation of the Hand
SO ORTHOPEDICS
LA English
DT Article
ID THERAPY
AB This article demonstrates an easy technique for applying a vacuum-assisted closure around an external fixator of the wrist and hand, with the aid of a surgical glove.
C1 [Gerszberg, Kenneth S.; Tan, Virak] Univ Med & Dent New Jersey, Dept Orthoped, New Jersey Med Sch, Newark, NJ 07103 USA.
C3 Rutgers University System; Rutgers University New Brunswick; Rutgers
   University Biomedical & Health Sciences
RP Tan, V (通讯作者)，Univ Med & Dent New Jersey, Dept Orthoped, New Jersey Med Sch, 140 Bergen St,ACC S,D Level Orthoped, Newark, NJ 07103 USA.
EM tanvi@umdnj.edu
CR DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   *KIN CONC INC, 2007, VAC THER SAF INF
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
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NR 7
TC 3
Z9 3
U1 0
U2 3
PU SLACK INC
PI THOROFARE
PA 6900 GROVE RD, THOROFARE, NJ 08086 USA
SN 0147-7447
EI 1938-2367
J9 ORTHOPEDICS
JI Orthopedics
PD NOV
PY 2009
VL 32
IS 11
BP 829
EP 831
DI 10.3928/01477447-20090922-16
PG 3
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 520YZ
UT WOS:000271887100004
PM 19902885
DA 2026-07-24
ER

PT J
AU Pontes, L
   de Azevedo, JS
   Secco, IL
   Pereira, HP
   Vieira, SCM
   Afonso, RQ
AF Pontes, Leticia
   de Azevedo, Juliana Szreider
   Secco, Izabela Linha
   Pereira, Higor Pacheco
   Vieira, Solange Cristina Moreira
   Afonso, Regiane Queiroz
TI Negative pressure therapy in pediatric patient with surgical site
   infection: experience report
SO REVISTA DA ESCOLA DE ENFERMAGEM DA USP
LA English
DT Article
DE Surgical Wound Infection; Negative-Pressure Wound Therapy; Wound
   Healing; Nursing Care; Pediatrics
ID TOXIC MEGACOLON; WOUND THERAPY; MANAGEMENT; CHILDREN
AB Objective: To describe the use of negative pressure wound therapy and hydrofiber dressing with silver in a pediatric patient with a hard-to-heal surgical wound infection. Method: This is a descriptive professional experience report on the use of conventional dressings and negative pressure wound therapy in a pediatric patient with a surgical wound infection. It was developed in 2023 at a Public Health Service that is a reference in the care of pediatric patients in the state of Paran & aacute;. Results: The surgical wound dehiscence started 12 days after peritoneostomy. Initially, the wound was treated with hydrofiber dressing with silver for 22 days and subsequently, negative pressure wound therapy was used for 15 days, regenerating the wound. Conclusion: Negative pressure wound therapy in pediatrics proved to be safe, effective and efficient for the treatment of complex wounds and corroborated the skin regeneration process, as did hydrofiber dressing with silver.
C1 [Pontes, Leticia; de Azevedo, Juliana Szreider; Secco, Izabela Linha; Pereira, Higor Pacheco] Univ Fed Parana, Programa Posgrad Prat Cuidado Saude, Curitiba, PR, Brazil.
   [Pontes, Leticia; de Azevedo, Juliana Szreider; Secco, Izabela Linha; Vieira, Solange Cristina Moreira; Afonso, Regiane Queiroz] Hosp Infantil Doutor Waldemar Monastier, Campo Largo, PR, Brazil.
C3 Universidade Federal do Parana
RP de Azevedo, JS (通讯作者)，Via Veneza 471,Casa 16, BR-83607050 Campo Largo, PR, Brazil.
EM julianaszreider@gmail.com
RI ; Pontes, Letícia/AAX-4668-2021
OI Szreider de Azevedo, Juliana/0000-0003-2817-8655; Afonso,
   Regiane/0000-0002-0087-1653; Pontes, Letícia/0000-0002-6766-7550;
   PEREIRA, HIGOR/0000-0001-5112-1118
CR Astasio-Picado A, 2022, J PERS MED, V12, DOI 10.3390/jpm12111813
   Bates-Jensen BM, 2019, WOUND REPAIR REGEN, V27, P386, DOI 10.1111/wrr.12714
   Brasil. Agencia Nacional de Vigilancia Sanitaria, 2017, Criterios diagnosticos de infeccao relacionada a assistencia a saude, V2
   Carvalho CD, 2022, ACTA CIR BRAS, V37, DOI 10.1590/acb370801
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   Desai J, 2020, CLIN EXP GASTROENTER, V13, P203, DOI 10.2147/CEG.S200760
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   Gomes João, 2021, NTQR, V8, P606
   Goswami AG, 2023, EUR J MED RES, V28, DOI 10.1186/s40001-023-01121-7
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   Leaper DJ, 2017, J HOSP INFECT, V95, P135, DOI 10.1016/j.jhin.2016.12.016
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NR 26
TC 0
Z9 1
U1 1
U2 4
PU UNIV SAO PAOLO
PI CERQUERA CESAR
PA AV  DR ENEAS DE CARVALHO AGUIAR, 419, CERQUERA CESAR, SP 05403-000,
   BRAZIL
SN 0080-6234
EI 1980-220X
J9 REV ESC ENFERM USP
JI Rev. Esc. Enferm. USP
PY 2024
VL 58
AR e20240077
DI 10.1590/1980-220X-REEUSP-2024-0077en
PG 8
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA N1E0W
UT WOS:001361835500001
PM 39589153
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Tuncel, U
   Turan, A
   Markoc, F
   Erkorkmaz, U
   Elmas, C
   Kostakoglu, N
AF Tuncel, Umut
   Turan, Aydin
   Markoc, Fatma
   Erkorkmaz, Unal
   Elmas, Cigdem
   Kostakoglu, Naci
TI Loofah Sponge as an Interface Dressing Material in Negative Pressure
   Wound Therapy: Results of an In Vivo Study
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE in vivo; loofah; negative pressure wound therapy; gauze; foam
ID VACUUM-ASSISTED CLOSURE; EVIDENCE-BASED RECOMMENDATIONS; GOURD
   LUFFA-CYLINDRICA; PORE-SIZE; CONTRACTION; GAUZE; FOAM; TRANSDUCTION;
   PROLIFERATION; ANGIOGENESIS
AB Since the introduction of negative pressure wound therapy (NPWT), the physiological effects of various interface dressing materials have been studied. The purpose of this experimental study was to compare the use of loofah sponge to standard polyurethane foam or a cotton gauze sponge. Three wounds, each measuring 3 cm x 3 cm, were created by full-thickness skin excision on the dorsal sides of 24 New Zealand adult white rabbits. The rabbits were randomly divided into four groups of six rabbits each. In group 1 (control), conventional saline-moistened gauze dressing was provided and changed at daily intervals. The remaining groups were provided NPWT dressings at -125 mm Hg continuous pressure. This dressing was changed every 3 days for 9 days; group 2 was provided polyurethane foam, group 3 had conventional saline-soaked antimicrobial gauze, and group 4 had loofah sponge. Wound area measurements and histological findings (inflammation, granulation tissue, neovascularization, and reepithelialization) were analyzed on days 3, 6, and 9. Wound area measurements at these intervals were significantly different between the control group and study groups (P <0.05). Granulation and neovascularization scores were also significantly different between the control and treatment groups at day 3 (P = 0.002). No differences in any of the healing variables studied were observed between the other three dressing materials. According to scanning electron microscopy analysis of the three interface materials, the mean pore size diameter of foam and gauze interface materials was 415.80 +/- 217.58 mu m and 912.33 +/- 116.88 mu m, respectively. The pore architecture of foam was much more regular than that of gauze. The average pore size diameter of loofah sponge was 736.83 +/- 23.01 mu m; pores were hierarchically located - ie, the smaller ones were usually peripheral and larger ones were central. For this study, the central part of loofah sponge was discarded to achieve a more homogenous structure of interface material. Loofah sponge study results were similar to those using gauze or foam, but the purchase price of loofah sponge is lower than that of currently available interface dressings. More experimental, randomized controlled studies are needed to confirm these results.
C1 [Tuncel, Umut; Turan, Aydin; Markoc, Fatma] Gaziosmanpasa Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-60100 Tokat, Turkey.
   [Erkorkmaz, Unal] Sakarya Univ, Fac Med, Dept Biostat, Sakarya, Turkey.
   [Elmas, Cigdem] Gazi Med Sch, Dept Histol & Embryol, Ankara, Turkey.
   [Kostakoglu, Naci] Gaziosmanpasa Univ, Dept Plast Reconstruct & Aesthet Surg, TR-60100 Tokat, Turkey.
C3 Tokat Gaziosmanpasa University; Sakarya University; Gazi University;
   Tokat Gaziosmanpasa University
RP Tuncel, U (通讯作者)，Gaziosmanpasa Univ, Fac Med Plast Reconstruct & Aesthet Surg, TR-60100 Tokat, Turkey.
EM drumuttuncel@gmail.com
RI Turan, Aydın/V-6669-2017; Tuncel, Umut/P-3185-2015; Erkorkmaz,
   Ünal/AAA-4241-2022; Elmas, Cigdem/AHE-1281-2022
OI Turan, Aydın/0000-0002-1540-1443; Tuncel, Umut/0000-0001-5029-2927;
   Erkorkmaz, Ünal/0000-0002-8497-4704; 
FU Scientific Research Projects Unit, Gaziosmanpasa University, Tokat,
   Turkey
FX This study was supported by a grant from the Scientific Research
   Projects Unit, Gaziosmanpasa University, Tokat, Turkey. KCI, San
   Antonio, TX, provided technical and device support.
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NR 58
TC 13
Z9 14
U1 0
U2 12
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD MAR
PY 2014
VL 60
IS 3
BP 37
EP 45
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AD9FU
UT WOS:000333571000005
PM 24610559
DA 2026-07-24
ER

PT J
AU Liu, L
   Chen, RF
   Jia, ZG
   Li, XT
   Tang, Y
   Zhao, XT
   Zhang, SQ
   Luo, L
   Fang, ZH
   Zhang, YZ
   Chen, MW
AF Liu, Lei
   Chen, Ruofei
   Jia, Zeguo
   Li, Xueting
   Tang, Ying
   Zhao, Xiaotong
   Zhang, Shiqi
   Luo, Li
   Fang, Zhaohui
   Zhang, Yuanzhi
   Chen, Mingwei
TI Downregulation of hsa-miR-203 in peripheral blood and wound margin
   tissue by negative pressure wound therapy contributes to wound healing
   of diabetic foot ulcers
SO MICROVASCULAR RESEARCH
LA English
DT Article
DE Type 2 diabetes; Foot ulcers; Negative pressure wound therapy;
   Keratinocytes; Hsa-miR-203; p63
ID VACUUM-ASSISTED CLOSURE; EXPRESSION; SKIN; MICRORNA-203;
   DIFFERENTIATION; MANAGEMENT; UPDATE; SERUM
AB Negative pressure wound therapy (NPWT) has been widely used in the treatment of chronic wounds, including diabetic foot ulcers (DFU) as the severe manifestation of diabetic foot. Hsa-miR-203 is proven to be correlated with the severity of DFU. To investigate whether NPWT influences hsa-miR-203 levels in persons with DFU, we detected hsa-miR-203 levels in peripheral plasma and wound margin tissue from the following patients: type 2 diabetic (T2D) patients with DFU (DFU group), T2D patients without DFU (NDFU group), patients with chronic skin ulcer and normal glucose tolerance (SUC group), and healthy volunteers with normal glucose tolerance (NC group). All patients in SUC group received NPWT. As contrast, some of patients in DFU group received NPWT (NPWT group) while others chose routine dressing therapy (non-NPWT group). In vitro experiments were also performed to determine influences of negative pressure on cell proliferation and migration of HaCaT cells (human keratinocytes). Results showed that before NPWT, levels of hsa-miR-203 in peripheral plasma (P-miR203) and wound margin tissue (T-miR-203) of DFU group were obviously increased compared to SUC group while expression of P-miR-203 decreased in NDFU group compared with NC group. After NPWT, levels of P-miR203 and T-miR-203 in DFU and SUC group were significantly lower than before. Changes of P-miR-203 and TmiR-203 after NPWT were positively correlated with 4-week ulcer healing rate in NPWT and SUC group. In vitro, negative pressure lowered the expression of hsa-miR-203, enhancing cell proliferation and migration in HaCaT cells via up-regulation of p63 protein. Meanwhile, the effects of negative pressure on cells were remarkable reduced by high-glucose intervention. Our study suggests that NPWT promotes DFU healing by reducing the expression of hsa-miR-203 in peripheral blood and wound tissue. The changes of hsa-miR-203 in peripheral blood and wound tissue may be related to the therapeutic effect of NPWT.
C1 [Liu, Lei; Jia, Zeguo; Li, Xueting; Tang, Ying; Zhao, Xiaotong; Zhang, Shiqi; Luo, Li; Chen, Mingwei] Anhui Med Univ, Affiliated Hosp 1, Dept Endocrinol, 218 Jixi Rd,Shushan Dist, Hefei 230022, Peoples R China.
   [Chen, Ruofei] Anhui Med Univ, Affiliated Hosp 1, Dept Rheumatol & Immunol, Hefei 230022, Peoples R China.
   [Fang, Zhaohui; Chen, Mingwei] Anhui Univ Chinese Med, Affiliated Hosp 1, Dept Endocrinol, Hefei 230031, Peoples R China.
   [Zhang, Yuanzhi] Chinese Acad Sci, Hefei Inst Phys Sci, Beijing, Peoples R China.
C3 Anhui Medical University; Anhui Medical University; Anhui University of
   Chinese Medicine; Chinese Academy of Sciences; Hefei Institutes of
   Physical Science, CAS
RP Chen, MW (通讯作者)，Anhui Med Univ, Affiliated Hosp 1, Dept Endocrinol, 218 Jixi Rd,Shushan Dist, Hefei 230022, Peoples R China.; Chen, MW (通讯作者)，Anhui Univ Chinese Med, Affiliated Hosp 1, Dept Endocrinol, Hefei 230031, Peoples R China.
EM chmw1@163.com
RI CHEN, MINGWEI/KHT-6744-2024
OI Liu, Lei/0000-0002-4725-7941
FU Key Research and Development Program of Anhui Province
   [202004a07020016]; Natural Science Foundation of Anhui Province
   [2108085MH269]
FX This study was supported by grants from the Key Research and Development
   Program of Anhui Province (Grant No. 202004a07020016) and the Natural
   Science Foundation of Anhui Province (Grant No. 2108085MH269).
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NR 44
TC 15
Z9 15
U1 0
U2 25
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0026-2862
EI 1095-9319
J9 MICROVASC RES
JI Microvasc. Res.
PD JAN
PY 2022
VL 139
AR 104275
DI 10.1016/j.mvr.2021.104275
EA NOV 2021
PG 10
WC Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA WW3XD
UT WOS:000717852800004
PM 34717969
DA 2026-07-24
ER

PT J
AU Verbelen, J
   Hoeksema, H
   Pirayesh, A
   Van Landuyt, K
   Monstrey, S
AF Verbelen, Jozef
   Hoeksema, Henk
   Pirayesh, Ali
   Van Landuyt, Koenraad
   Monstrey, Stan
TI Exposed tibial bone after burns: Flap reconstruction versus dermal
   substitute
SO BURNS
LA English
DT Article
DE Exposed tibia; Flap surgery; Flap reconstruction; Dermal substitute;
   Glyaderm; Negative pressure wound therapy; Full thickness burn
ID HEPARIN-INDUCED THROMBOCYTOPENIA; VACUUM-ASSISTED CLOSURE; SOFT-TISSUE
   RECONSTRUCTION; NEGATIVE-PRESSURE THERAPY; LOWER-EXTREMITY; ARTIFICIAL
   DERMIS; SUBATMOSPHERIC PRESSURE; PLASTIC-SURGERY; MANAGEMENT; FAILURE
AB A 44 years old male patient had suffered extensive 3rd degree burns on both legs, undergoing thorough surgical debridement, resulting in both tibias being exposed.
   Approximately 5 months after the incident he was referred to the Department of Plastic and Reconstructive Surgery of the University Hospital Gent, Belgium, to undergo flap reconstruction.
   Free flap surgery was performed twice on both lower legs but failed on all four occasions.
   In between flap surgery, a dermal substitute (Integra (R)) was applied, attempting to cover the exposed tibias with a layer of soft tissue, but also without success.
   In order to promote the development of granulation tissue over the exposed bone, small holes were drilled in both tibias with removal of the outer layer of the anterior cortex causing the bone to bleed and subsequently negative pressure wound therapy (NPWT) was applied.
   The limited granulation tissue resulting from this procedure was then covered with a dermal substitute (Glyaderm (R)), consisting of acellular human dermis with an average thickness of 0.25 mm.
   This dermal substitute was combined with a NPWT-dressing, and then served as an extracellular matrix (ECM), guiding the distribution of granulation tissue over the remaining areas of exposed tibial bone.
   Four days after initial application of Glyaderm (R) combined with NPWT both tibias were almost completely covered with a thin coating of soft tissue.
   In order to increase the thickness of this soft tissue cover two additional layers of Glyaderm (R) were applied at intervals of approximately 1 week. One week after the last Glyaderm (R) application both wounds were autografted.
   The combination of an acellular dermal substitute (Glyaderm (R)) with negative pressure wound therapy and skin grafting proved to be an efficient technique to cover a wider area of exposed tibial bone in a patient who was not a candidate for free flap surgery. An overview is also provided of newer and simpler techniques for coverage of exposed bone that could question the universal plastic surgery paradigm that flap surgery is the only way to cover these defects. (C) 2015 Elsevier Ltd and ISBI. All rights reserved.
C1 [Verbelen, Jozef; Hoeksema, Henk; Van Landuyt, Koenraad; Monstrey, Stan] Ghent Univ Hosp, Burn Ctr, Dept Plast & Reconstruct Surg, B-9000 Ghent, Belgium.
   [Pirayesh, Ali] Plast Surg, Amsterdam, Netherlands.
C3 Ghent University; Ghent University Hospital
RP Monstrey, S (通讯作者)，Ghent Univ Hosp, Burn Ctr, Dept Plast Surg, B-9000 Ghent, Belgium.
EM Stan.Monstrey@UGent.be
OI Hoeksema, Henik/0000-0003-3160-4539
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NR 51
TC 28
Z9 32
U1 0
U2 18
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0305-4179
EI 1879-1409
J9 BURNS
JI Burns
PD MAR
PY 2016
VL 42
IS 2
BP E31
EP E37
DI 10.1016/j.burns.2015.08.013
PG 7
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA DG6FW
UT WOS:000372179600005
PM 26376411
DA 2026-07-24
ER

PT J
AU Arundel, C
   Mandefield, L
   Fairhurst, C
   Baird, K
   Saramago, P
   Gkekas, A
   Macefield, R
   Blazeby, J
   Corbacho, B
   Dixon, S
   Dumville, J
   Hatfield, J
   Hewitt, C
   Lee, M
   Mott, A
   Oswald, A
   Pinkney, T
   Stubbs, N
   Swan, S
   Torgerson, D
   Wilkinson, J
   Wilson, L
   Zahra, S
   Chetter, I
AF Arundel, Catherine
   Mandefield, Laura
   Fairhurst, Caroline
   Baird, Kalpita
   Saramago, Pedro
   Gkekas, Athanasios
   Macefield, Rhiannon
   Blazeby, Jane
   Corbacho, Belen
   Dixon, Stephen
   Dumville, Jo
   Hatfield, Josie
   Hewitt, Catherine
   Lee, Matthew
   Mott, Andrew
   Oswald, Angela
   Pinkney, Thomas
   Stubbs, Nikki
   Swan, Samantha
   Torgerson, David
   Wilkinson, Jacqueline
   Wilson, Lyn
   Zahra, Sabeen
   Chetter, Ian
CA SWHSI 2 Trial Investigators
TI Clinical and cost-effectiveness of negative pressure wound therapy
   versus usual care for surgical wounds healing by secondary intention:
   the SWHSI 2 pragmatic RCT
SO HEALTH TECHNOLOGY ASSESSMENT
LA English
DT Article
ID MULTICENTER; ULCERS; TRIAL; FOOT; DRESSINGS; ALGINATE; CLOSURE; DISEASE
AB Background: Surgical wounds healing by secondary intention occur if a surgical wound is not closed or dehisces following primary closure. Surgical wounds healing by secondary intention are common and adversely affect patients' quality of life. Treatment is often prolonged, complex and expensive. Negative pressure wound therapy applies a controlled vacuum to the wound and is increasingly used to promote surgical wound healing by secondary intention despite limited rigorous evidence for the clinical and cost-effectiveness of negative pressure wound therapy to augment surgical wound healing by secondary intention. Objective: Assess the clinical and cost-effectiveness of negative pressure wound therapy versus usual care (no negative pressure wound therapy) in treating surgical wounds healing by secondary intention. Design and methods: A pragmatic, two-arm, parallel-group, randomised controlled superiority trial. Twentyeight UK NHS Trusts randomised adult patients with a surgical wounds healing by secondary intention to receive negative pressure wound therapy or usual care (no negative pressure wound therapy). The planned sample size was 696 participants. Participants were followed up for 12 months via weekly telephone contact to collect the primary outcome (time to healing: full cover with no scab in days since randomisation) and clinical secondary outcomes: wound healing, surgical site infection, pain, hospital re-admission, current treatment and reasons for treatment change (if applicable), reoperation, amputation, antibiotic use, death. Patient-reported outcomes (pain, health-related quality of life and resource use) were collected by postal questionnaire at 3, 6 and 12 months. Validation of the Bluebelle Wound Healing Questionnaire, a patient-reported measure of surgical site infection, was also undertaken. A cost-effectiveness decision model considering all available evidence, and a within-trial cost-utility analysis, was also undertaken to evaluate the cost-effectiveness of negative pressure wound therapy against usual care. Neither participants nor the investigators were blind to treatment allocation. Results: Between 15 May 2019 and 13 January 2023, 686 participants were recruited, randomised and included in the analysis (negative pressure wound therapy n = 349; usual care n = 337). Most participants had a single surgical wound healing by secondary intention (n = 622, 90.7%), located on the foot (n = 551, 80.3%) or leg (n = 69, 10.1%) arising following vascular surgery (n = 619, 90.2%). Most participants had comorbidities; diabetes (n = 549, 80.0%), cardiovascular disease (n = 446, 65.0%) and/or peripheral vascular disease (n = 349, 50.9%). Median time to healing was 187 days (negative pressure wound therapy) versus 195 days (usual care), with no evidence that negative pressure wound therapy reduced the time to wound healing compared to usual care (hazard ratio 1.08, 95% CI 0.88 to 1.32; p = 0.47). Odds of re-admission, reoperation, surgical site infection and antibiotic use were slightly higher, and odds of amputation or death slightly lower for negative pressure wound therapy participants. These results were not clinically or statistically significant. Bluebelle Wound Healing Questionnaire, quality of life and wound pain scores were not statistically significantly different at any time point. Serious adverse events were rare (nine negative pressure wound therapy vs. five usual-care participants).
   Both cost-effectiveness analyses concluded that negative pressure wound therapy generates higher costs and marginally higher quality-adjusted life-years than usual care, although findings were statistically insignificant. The probability of negative pressure wound therapy being cost-effective was under the recommended National Institute for Health and Care Excellence cost-effectiveness thresholds. The Bluebelle Wound Healing Questionnaire was acceptable to participants, had low levels of missing data and demonstrated good levels of sensitivity and specificity in the detection of surgical site infection in surgical wounds healing by secondary intention. Limitations: The trial included a high proportion of diabetic participants with foot wounds, which may affect study generalisability. Negative pressure wound therapy use for 'wound management', common in certain surgical specialties, was not assessed in this study. Conclusions: Negative pressure wound therapy is not clinically or cost-effective in augmenting healing in patients with surgical wounds healing by secondary intention, particularly those with comorbidities. Future work: Evaluation of methods to treat or prevent infection of surgical wounds healing by secondary intention and evaluation of negative pressure wound therapy for 'wound management' are recommended. Funding: This synopsis presents independent research funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme as award number 17/42/94. A plain language summary of this synopsis is available on the NIHRJournals Library Website https://doi.org/10.3310/ GJIC1716.
C1 [Arundel, Catherine; Mandefield, Laura; Fairhurst, Caroline; Baird, Kalpita; Gkekas, Athanasios; Corbacho, Belen; Hewitt, Catherine; Mott, Andrew; Swan, Samantha; Torgerson, David; Wilkinson, Jacqueline; Zahra, Sabeen] Univ York, York Trials Unit, York, England.
   [Saramago, Pedro] Univ York, Ctr Hlth Econ, York, England.
   [Macefield, Rhiannon; Blazeby, Jane] Univ Hosp Bristol & Weston NHS Fdn Trust, Natl Inst Hlth & Care Res NIHR, Bristol Biomed Res Ctr, Bristol, England.
   [Macefield, Rhiannon; Blazeby, Jane] Univ Bristol, Bristol, England.
   [Dixon, Stephen; Hatfield, Josie; Oswald, Angela; Chetter, Ian] Hull Univ Teaching Hosp NHS Trust, Kingston Upon Hull, England.
   [Dumville, Jo] Univ Manchester, Manchester, England.
   [Lee, Matthew] Sheffield Teaching Hosp NHS Fdn Trust, Sheffield, England.
   [Pinkney, Thomas] Univ Birmingham, Inst Appl Hlth Res, Birmingham, England.
   [Stubbs, Nikki] NCS Wound Care Ltd, Leeds, England.
   [Wilson, Lyn] Mid Yorkshire Teaching NHS Trust, Wakefield, England.
   [Chetter, Ian] Hull York Med Sch, Kingston Upon Hull, England.
   [Chetter, Ian] Univ Hull, Kingston Upon Hull, England.
C3 University of York - UK; University of York - UK; University of Bristol;
   University of Manchester; University of Sheffield; University of
   Birmingham; University of Hull; University of York - UK; University of
   Hull
RP Arundel, C (通讯作者)，Univ York, York Trials Unit, York, England.
EM catherine.arundel@york.ac.uk
RI ; Blazeby, Jane/H-6703-2019; Mott, Andrew/HLQ-6922-2023; Pinkney,
   Thomas/HGA-4022-2022; Dumville, Jo/O-7867-2014; Torgerson,
   David/L-4566-2019
OI Macefield, Rhiannon/0000-0002-6606-5427; Blazeby,
   Jane/0000-0002-3354-3330; Mott, Andrew/0000-0001-7844-9033; 
FU National Institute for Health and Care Research (NIHR) Health Technology
   Assessment programme [17/42/94]; National Institutes of Health Research
   (NIHR) [17/42/94] Funding Source: National Institutes of Health Research
   (NIHR)
FX This synopsis presents independent research funded by the National
   Institute for Health and Care Research (NIHR) Health Technology
   Assessment programme as award number 17/42/94.
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NR 66
TC 0
Z9 0
U1 0
U2 0
PU NIHR JOURNALS LIBRARY
PI SOUTHAMPTON
PA UNIV SOUTHAMPTON, EVALUATION, TRIALS & STUDIES COORDINATING CENTRE,
   ALPHA HOUSE, ENTERPRISE RD, SOUTHAMPTON, SO16 7NS, ENGLAND
SN 1366-5278
EI 2046-4924
J9 HEALTH TECHNOL ASSES
JI Health Technol. Assess.
PD MAY
PY 2026
VL 30
IS 32
AR 1716
DI 10.3310/GJIC1716
PG 50
WC Health Care Sciences & Services
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services
GA HV7XV
UT WOS:001763868000001
PM 42104753
OA Green Submitted, Green Published, gold
DA 2026-07-24
ER

PT J
AU Lindstedt, S
   Hlebowicz, J
AF Lindstedt, Sandra
   Hlebowicz, Joanna
TI Blood flow response in small intestinal loops at different depths during
   negative pressure wound therapy of the open abdomen
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Intestinal wall; Microvascular blood flow; Negative pressure wound
   therapy; Open abdomen
ID ABDOMINAL COMPARTMENT SYNDROME; VACUUM-ASSISTED CLOSURE; INTRAABDOMINAL
   HYPERTENSION; ENTEROCUTANEOUS FISTULA; PROTECTIVE DISC; MANAGEMENT;
   LAPAROSTOMY; WALL; RECOMMENDATIONS; SEPSIS
AB High closure rates of the open abdomen have been reported following negative pressure wound therapy (NPWT). However, the method has occasionally been associated with increased development of intestinal fistulae. We have previously shown that the application of NPWT to the open abdomen causes a decrease in microvascular blood flow in the small intestinal loop and the omentum adjacent to the visceral protective layer of the dressing. In this study we investigate whether the negative pressure affects only small intestinal loops lying directly below the dressing or if it also affects small intestinal loops that are not in direct contact with the dressing. Six pigs underwent midline incision and application of NPWT to the open abdomen. The microvascular blood flow was measured in four intestinal loops at different depths from the visceral protective layer, at two different locations: beneath the dressing and at the anterior abdominal wall, before and after the application of NPWT of -50, -70, -100, -120, -150 and -170 mmHg, using laser Doppler velocimetry. Negative pressures between -50 and -170 mmHg caused a significant decrease in the microvascular blood flow in the intestinal loops in direct contact with the visceral protective layer. A slight, but significant, decrease in blood flow was also seen in the intestinal loops lying beneath these loops. The decrease in microvascular blood flow increased with the amount of negative pressure applied. No difference in blood flow was seen in the intestinal loops lying deeper in the abdominal cavity. A decrease in blood flow was seen in the upper two intestinal loops located apically and anteriorly, but not in the lower two, indicating that this is a local effect and that pressure decreases with distance from the source. A long-term decrease in blood flow in the intestinal wall may induce ischaemia and secondary necrosis in the intestinal wall, which could promote the development of intestinal fistulae. We believe that NPWT of the open abdomen is a very effective treatment, but that it could be improved by gaining more knowledge on the mechanisms involved.
C1 [Lindstedt, Sandra] Univ Lund Hosp, Dept Cardiothorac Surg, S-21112 Lund, Sweden.
   [Hlebowicz, Joanna] Lund Univ, Dept Med, Malmo, Sweden.
C3 Lund University; Skane University Hospital; Lund University
RP Lindstedt, S (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, S-21112 Lund, Sweden.
EM sandra.lindstedt.ingemansson@gmail.com
RI Lindstedt, Sandra/AEM-2892-2022
OI Lindstedt, Sandra/0000-0003-4484-6473
FU Region Skane
FX We would like to thank our funding source Region Skane.
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NR 32
TC 5
Z9 6
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD AUG
PY 2013
VL 10
IS 4
BP 411
EP 417
DI 10.1111/j.1742-481X.2012.00998.x
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 187YM
UT WOS:000322157600011
PM 22698003
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Macionis, V
AF Macionis, Valdas
TI Negative Pressure Wound Therapy: Supra-Physiological or Just Physical
   Effects of Positive Pressure?
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Letter
DE Negative-pressure wound therapy; Physiology; Dressings; Wound closure
   techniques
ID LOWER-LIMB RECONSTRUCTION; FLAPS; SAFETY
AB This communication provides a new insight into the unexplained physiology of beneficial effects of negative pressure wound therapy (NPWT). Possible mechanisms of beneficial effects of NPWT in failing replantation and free tissue transfer are discussed. Positive pressure generated by NPWT as well as its draining action creates exudate-free tight tissue-to-tissue interface, which may enhance neovascularization.
EM valdas.macionis.md@gmail.com
RI Macionis, Valdas/AGR-1693-2022
OI Macionis, Valdas/0000-0002-7517-895X
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NR 22
TC 0
Z9 0
U1 1
U2 1
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD SEP
PY 2025
VL 24
IS 3
BP 736
EP 738
DI 10.1177/15347346221144145
EA DEC 2022
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 5JR4E
UT WOS:000895536700001
PM 36476187
DA 2026-07-24
ER

PT J
AU Gu, HY
   Zhao, XQ
   Sun, Y
   Ding, YY
   Rong, OY
AF Gu, Haiyun
   Zhao, Xiaoqin
   Sun, Yi
   Ding, Yiyi
   Rong, Ouyang
TI Negative-pressure wound therapy compared with advanced moist wound
   therapy: A comparative study on healing efficacy in diabetic foot ulcers
SO SURGERY
LA English
DT Article
ID MANAGEMENT; INSTILLATION; SURGERY; CARE
AB Objective: This randomized controlled trial aimed to compare the efficacy of negative-pressure wound therapy with advanced moist wound therapy in managing diabetic foot ulcers. Methods: A total of 450 participants with diabetic foot ulcers were randomized to receive either negative-pressure wound therapy (n = 204) or advanced moist wound therapy (n = 246) over 18 months. The primary outcome was complete ulcer closure, with secondary outcomes including time to closure, wound size reduction, infection rates, recurrence, and amputation rates. Wound dimensions were measured using digital planimetry, and Kaplan-Meier survival analysis was applied to assess time to closure. Result: Analysis revealed statistically significant differences in clinical outcomes between treatment modalities. In the negative-pressure wound therapy group (n = 204), complete ulcer closure was achieved in 177 patients (87%), which was significantly greater than the advanced moist wound therapy group (n = 246) with 72 patients (29%) (P < .001). Although the mean time to wound closure was marginally extended in the negative-pressure wound therapy group (73 +/- 45 days vs 64 +/- 49 days; P = .045), this cohort demonstrated substantially more significant wound area reduction (48% +/- 15 vs 25% +/- 30; P < .001). Secondary outcome analysis revealed that negative-pressure wound therapy was associated with markedly reduced adverse events: wound infection (40 patients [20%] vs 95 patients [39%]; P < .001), ulcer recurrence (40 patients [20%] vs 113 patients [46%]; P < .001), and amputation rates (30 patients [15%] vs 132 patients [54%]; P < .001). Longitudinal assessment through Kaplan-Meier survival analysis demonstrated significantly greater wound closure probability and reduced complication risk in the negative-pressure wound therapy group throughout the follow-up period (log-rank P < .001). Conclusion: Negative-pressure wound therapy is significantly more effective than advanced moist wound therapy in treating diabetic foot ulcers, demonstrating superior outcomes in wound closure, infection control, and amputation prevention. This study highlights negative-pressure wound therapy as the preferred treatment option for complex diabetic foot ulcers, warranting further research into its longterm benefits and cost-effectiveness. (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
C1 [Gu, Haiyun; Zhao, Xiaoqin; Sun, Yi; Ding, Yiyi; Rong, Ouyang] Nantong Univ, Affiliated Hosp, Dept Endocrinol & Metab, Nantong 226001, Peoples R China.
C3 Nantong University
RP Rong, OY (通讯作者)，Nantong Univ, Affiliated Hosp, Dept Endocrinol & Metab, Nantong 226001, Peoples R China.
EM 13962811781@163.com
RI Ding, Yiyi/KEH-1318-2024; zhao, xiaoqing/KWT-6534-2024
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NR 45
TC 13
Z9 14
U1 9
U2 22
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
EI 1532-7361
J9 SURGERY
JI Surgery
PD APR
PY 2025
VL 180
AR 109098
DI 10.1016/j.surg.2024.109098
EA JAN 2025
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA U6O3D
UT WOS:001412957800001
PM 39793417
DA 2026-07-24
ER

PT J
AU Dumville, JC
   Webster, J
   Evans, D
   Land, L
AF Dumville, Jo C.
   Webster, Joan
   Evans, Debra
   Land, Lucy
TI Negative pressure wound therapy for treating pressure ulcers
SO COCHRANE DATABASE OF SYSTEMATIC REVIEWS
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED CONTROLLED-TRIAL;
   COST-EFFECTIVENESS; RISK-FACTORS; PREVALENCE; EFFICACY; CARE;
   METAANALYSIS; MANAGEMENT; SORES
AB Background
   Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Negative pressure wound therapy (NPWT) is a treatment option for pressure ulcers; a clear, current overview of the evidence is required to facilitate decision-making regarding its use.
   Objectives
   To assess the effects of negative pressure wound therapy for treating pressure ulcers in any care setting.
   Search methods
   For this review, we searched the following databases in May 2015: the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL; The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication.
   Selection criteria
   Published or unpublished randomised controlled trials (RCTs) comparing the effects of NPWT with alternative treatments or different types of NPWT in the treatment of pressure ulcers (stage II or above).
   Data collection and analysis
   Two review authors independently performed study selection, risk of bias assessment and data extraction.
   Main results
   The review contains four studies with a total of 149 participants. Two studies compared NPWT with dressings; one study compared NPWT with a series of gel treatments and one study compared NPWT with 'moist wound healing'. One study had a 24-week follow-up period, and two had a six-week follow-up period, the follow-up time was unclear for one study. Three of the four included studies were deemed to be at a high risk of bias from one or more 'Risk of bias' domains and all evidence was deemed to be of very low quality. Only one study reported usable primary outcome data (complete wound healing), but this had only 12 participants and there were very few events (only one participant healed in the study). There was little other useful data available from the included studies on positive outcomes such as wound healing or negative outcomes such as adverse events.
   Authors' conclusions
   There is currently no rigorous RCT evidence available regarding the effects of NPWT compared with alternatives for the treatment of pressure ulcers. High uncertainty remains about the potential benefits or harms, or both, of using this treatment for pressure ulcer management.
C1 [Dumville, Jo C.] Univ Manchester, Sch Nursing Midwifery & Social Work, Manchester M13 9PL, Lancs, England.
   [Webster, Joan] Royal Brisbane & Womens Hosp, Ctr Clin Nursing, Brisbane, Qld, Australia.
   [Evans, Debra] Birmingham City Univ, Div Community Hlth & Social Work, Birmingham, W Midlands, England.
   [Land, Lucy] Birmingham City Univ, Ctr Hlth & Social Care Res, Birmingham, W Midlands, England.
C3 University of Manchester; Royal Brisbane & Women's Hospital; Birmingham
   City University; Birmingham City University
RP Dumville, JC (通讯作者)，Univ Manchester, Sch Nursing Midwifery & Social Work, Manchester M13 9PL, Lancs, England.
EM jo.dumville@manchester.ac.uk
RI ; Dumville, Jo/O-7867-2014
OI Land, Lucy/0000-0001-8634-8056; Dumville, Jo/0000-0002-6546-3685
FU School of Nursing, Midwifery and Social Work, University of Manchester,
   UK; NIHR Cochrane Programme, UK [13/89/08]; National Institute for
   Health Research, via Cochrane Infrastructure; Cochrane Programme;
   National Institute for Health Research [13/89/08] Funding Source:
   researchfish
FX Internal sources School of Nursing, Midwifery and Social Work,
   University of Manchester, UK. External sources NIHR Cochrane Programme
   Grant Project: 13/89/08 - High Priority Cochrane Reviews in Wound
   Prevention and Treatment, UK. This project was supported by the National
   Institute for Health Research, via Cochrane Infrastructure and Cochrane
   Programme Grant funding to Cochrane Wounds. The views and opinions
   expressed therein are those of the authors and do not necessarily
   reflect those of the Systematic Reviews Programme, NIHR, NHS or the
   Department of Health, UK.
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NR 68
TC 53
Z9 63
U1 2
U2 34
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1469-493X
EI 1361-6137
J9 COCHRANE DB SYST REV
JI Cochrane Database Syst Rev.
PY 2015
IS 5
AR CD011334
DI 10.1002/14651858.CD011334.pub2
PG 42
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA CK1UR
UT WOS:000355993600056
PM 25992684
OA Bronze
DA 2026-07-24
ER

PT J
AU Liu, DH
   Zhang, LH
   Li, TT
   Wang, GQ
   Du, HL
   Hou, HP
   Han, L
   Tang, PF
AF Liu, Daohong
   Zhang, Lihai
   Li, Tongtong
   Wang, Guoqi
   Du, Hailong
   Hou, Hongping
   Han, Li
   Tang, Peifu
TI Negative-Pressure Wound Therapy Enhances Local Inflammatory Responses in
   Acute Infected Soft-Tissue Wound
SO CELL BIOCHEMISTRY AND BIOPHYSICS
LA English
DT Article
DE Infection; Negative-pressure wound therapy; Inflammatory; Cytokine
ID VACUUM-ASSISTED CLOSURE; IL-1 RECEPTOR ANTAGONIST;
   STAPHYLOCOCCUS-AUREUS; GENE-EXPRESSION; NEUTROPHIL RECRUITMENT; IN-VIVO;
   INTERLEUKIN-8; MECHANISMS; SYSTEM; INJURY
AB Clinical studies found that negative-pressure wound therapy (NPWT) displayed significant clinical benefits in the healing of infected wounds. However, the effect of NPWT on local inflammatory responses in acute infected soft-tissue wound has not been investigated thoroughly. The purpose of this study was to test the impact of NPWT on local expression of proinflammatory cytokines, amount of neutrophils, and bacterial bioburden in wound from acute infected soft-tissue wounds. Full-thickness wounds were created on the back of rabbits, and were inoculated with Staphylococcus aureus strain ATCC29213. The wounds were treated with sterile saline-moistened gauze dressings and NPWT with continuous negative pressure (-125 mmHg). Wound samples were harvested on days 0 (6 h after bacterial inoculation), 2, 4, 6, and 8 at the center of wound beds before irrigation for real-time PCR analysis of gene expression of IL-1 beta, IL-8, and TNF-alpha. Wound biopsies were examined histologically for neutrophil quantification in different layers of tissue. Quantitative bacterial cultures at the same time point were analyzed for bacterial clearance. Application of NPWT to acute infected wounds in rabbits was compared with treatment with sterile saline-moistened gauze, over an 8-day period. NPWT-treated wounds exhibited earlier and greater peaking of IL-1 beta and IL-8 expression and decrease in TNF-alpha expression over the early 4 days (P < 0.05). Furthermore, histologic examination revealed that significantly increased neutrophil count was observed in the shallow layer in wound biopsies of NPWT treatment at day 2 (P < 0.001). In addition, there was a statistically significant decrease of bacteria load from baseline (day 0) at days 2 and 8 in NPWT group (P < 0.05). In conclusion, this study demonstrates that NPWT of acute infected soft-tissue wounds leads to increased local IL-1 beta and IL-8 expression in early phase of inflammation, which may trigger accumulation of neutrophils and thus accelerate bacterial clearance. Meanwhile, the success of NPWT in the treatment of acute wounds can attenuate the expression of TNF-alpha, and the result may partly explain how NPWT can avoid significantly impairing wound healing.
C1 [Liu, Daohong; Zhang, Lihai; Li, Tongtong; Wang, Guoqi; Du, Hailong; Hou, Hongping; Tang, Peifu] Peoples Liberat Army, Dept Orthopaed, Genearl Hosp, Beijing 100853, Peoples R China.
   [Han, Li] Chinese PLA Inst Dis Control & Prevent, Ctr Hosp Infect Control, Beijing 100071, Peoples R China.
RP Tang, PF (通讯作者)，Peoples Liberat Army, Dept Orthopaed, Genearl Hosp, 28 Fuxing Rd, Beijing 100853, Peoples R China.
EM hanlicdc@163.com; drpeifutang@163.com
RI Hou, Hongping/ABQ-8065-2022
OI Tang, Peifu/0000-0003-4279-1704
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   Schultz G, 1994, ACUTE CHRONIC WOUNDS, P413
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   STRIETER RM, 1990, AM J RESP CELL MOL, V2, P321, DOI 10.1165/ajrcmb/2.4.321
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NR 44
TC 37
Z9 40
U1 1
U2 15
PU HUMANA PRESS INC
PI TOTOWA
PA 999 RIVERVIEW DRIVE SUITE 208, TOTOWA, NJ 07512 USA
SN 1085-9195
EI 1559-0283
J9 CELL BIOCHEM BIOPHYS
JI Cell Biochem. Biophys.
PD SEP
PY 2014
VL 70
IS 1
BP 539
EP 547
DI 10.1007/s12013-014-9953-0
PG 9
WC Biochemistry & Molecular Biology; Biophysics; Cell Biology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biochemistry & Molecular Biology; Biophysics; Cell Biology
GA AN4XN
UT WOS:000340593200075
PM 24748178
DA 2026-07-24
ER

PT J
AU Kazez, M
   Önce, G
   Ayas, O
   Seker, AS
   Kürüm, H
AF Kazez, Muhammed
   Once, Gokhan
   Ayas, Orhan
   Seker, Ali Sami
   Kurum, Huseyin
TI Comparison of negative pressure wound therapy and wet-to-dry dressing
   after fasciotomy in earthquake victims: A retrospective cohort study
SO ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA &
   EMERGENCY SURGERY
LA English
DT Article
DE Compartment syndrome; fasciotomy; gradual approximation; negative
   pressure wound therapy; wet-to-dry dressing
ID VACUUM-ASSISTED CLOSURE; LEG
AB BACKGROUND: This study aimed to compare the clinical effectiveness of negative pressure wound therapy (NPWT) with traditional wet-to-dry dressings in patients undergoing fasciotomy for acute compartment syndrome of the lower extremities following the February 6, 2023 earthquakes in Kahramanmara & scedil;, T & uuml;rkiye. METHODS: This retrospective cohort study included 28 patients (15 males, 13 females) admitted to our hospital between February 6 and March 6, 2023, who underwent fasciotomy for lower extremity acute compartment syndrome. A total of 109 fasciotomy incisions were performed across 60 extremities. Of these, 78 wounds were managed with NPWT and 31 with wet-to-dry dressings. Group allocation was determined by NPWT device availability during the disaster period. All patients were managed using a standardized wound closure protocol, including serial debridement followed by primary closure or split-thickness skin grafting when indicated. Outcomes compared between groups included number of debridements, infection rate, primary wound closure, graft requirement, dressing-related complications, and length of hospital stay. RESULTS: The NPWT group required significantly fewer debridements (p<0.05). Dressing-related complications and the need for additional dressing interventions were significantly higher in the wet-to-dry group (p<0.05). No significant differences were observed between groups in infection rate, primary wound closure, graft requirement, or length of hospital stay (p>0.05). Among pediatric patients, infection rates were lower than in adults, whereas unplanned dressing changes were significantly more frequent (p<0.05). CONCLUSION: NPWT is an effective wound management modality in fasciotomy patients, even under disaster conditions. It significantly reduced the need for debridement and dressing-related complications compared to traditional methods, despite similar outcomes in infection and wound closure. These findings support the preferential use of NPWT in mass-casualty settings, where healthcare personnel and resources may be limited. In addition to its clinical benefits, NPWT offers logistical advantages by simplifying wound care and reducing healthcare workload. Future prospective, randomized, multicenter studies are needed to confirm these findings and evaluate the broader applicability and cost-effectiveness of NPWT in both disaster and routine clinical settings.
C1 [Kazez, Muhammed; Once, Gokhan; Ayas, Orhan; Seker, Ali Sami; Kurum, Huseyin] Elazig Fethi Sekin City Hosp, Dept Orthoped & Traumatol, Elazig, Turkiye.
RP Kazez, M (通讯作者)，Elazig Fethi Sekin City Hosp, Dept Orthoped & Traumatol, Elazig, Turkiye.
EM mkzz23@hotmail.com
CR Abu-Zidan FM, 2024, TURK J EMERG MED, V24, P67, DOI 10.4103/tjem.tjem_11_24
   Afzal H, 2024, SURG INFECT, V25, P199, DOI 10.1089/sur.2023.299
   Alkhalifah Mohammed K, 2019, Sultan Qaboos Univ Med J, V19, pe192, DOI [10.18295/squmj.2019.19.03.004, 10.18295/squmj.2019.19.03.004]
   Bussell HR, 2019, EUR J TRAUMA EMERG S, V45, P809, DOI 10.1007/s00068-018-0985-9
   Dağlar B, 2022, Türk Ortopedi ve Travmatoloji Birliği Derneği, V21, P283, DOI 10.5578/totbid.dergisi.2022.38
   Igoumenou VG, 2019, Compartment Syndrome, P83, DOI [10.1007/978-3-030-22331-1_9, DOI 10.1007/978-3-030-22331-1_9]
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NR 24
TC 0
Z9 0
U1 3
U2 3
PU TURKISH ASSOC TRAUMA EMERGENCY SURGERY
PI ISTANBUL
PA KOPRULU MEHMET PASA SOC, DENIZ ABDAL MAH, DADASOGLU AP, 25-1 SEHREMINI,
   ISTANBUL, 00000, Turkiye
SN 1306-696X
EI 1307-7945
J9 ULUS TRAVMA ACIL CER
JI Ulus. Travma Acil Cerrahi Derg.
PD JUN
PY 2026
VL 32
IS 6
BP 745
EP 753
DI 10.14744/tjtes.2025.20250
PG 9
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA JD4QV
UT WOS:001786710800015
PM 42261853
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Mo, R
   Ma, ZJ
   Chen, C
   Meng, XY
   Tan, Q
AF Mo, Ran
   Ma, Zhouji
   Chen, Chen
   Meng, Xueyong
   Tan, Qian
TI Short- and long-term efficacy of negative-pressure wound therapy in
   split-thickness skin grafts: a retrospective study
SO ANNALS OF PALLIATIVE MEDICINE
LA English
DT Article
DE Negative-pressure wound therapy (NPWT); skin graft; survival rate; scar
ID VACUUM-ASSISTED CLOSURE; DONOR SITE; MANAGEMENT; RECONSTRUCTION;
   MULTICENTER; TIE
AB Background: Graft fixation is essential for the successful survival of skin grafts. Negative-pressure wound therapy (NPWT) can be utilized for fixing a skin graft, ensuring adhesion of the graft with continuous and uniform pressure. However, the reported short- and long-term efficacy of NPWT in split-thickness skin grafts (STSGs) is inconsistent, with few studies on the long-term efficacy (scar quality). To clarify the appropriate methods of skin graft fixation, we conducted a single-center retrospective study on the short-and long-term effects of skin grafting using different fixation methods.
   Methods: This study retrospectively analyzed patients who underwent STSG from December 2010 to June 2019. The patients were divided into two groups based on the skin graft-fixing method: an NPWT group and a conventional mechanical fixation group. Medical data including age, sex, underlying diseases, wound etiology, recipient site, surgical methods, surgical outcomes, postoperative complications, and follow-up data (Vancouver Scar Scale score and Patient and Observer Scar Assessment Scale score) were analyzed.
   Results: A total of 392 cases were ultimately included in the analysis. Among them, 218 cases were fixed with NPWT for skin grafting and 174 with conventional mechanical fixation. No significant differences in baseline data were noted between the two groups. The total graft survival rate in the NPWT group was higher than that in the conventional mechanical fixation group (86.7% vs. 74.1%, P=0.002). Moreover, the infection rate in the NPWT group was lower than that in the conventional mechanical fixation group (5.5% vs. 13.2%, P=0.008). In terms of scar quality, no significant difference was observed, except for in the hand. Overall, the scar surface regularity was better in the NPWT group than in the control group. (P=0.019 for Patient Scar Assessment Scale, P=0.025 for Observer Scar Assessment Scale).
   Conclusions: NPWT is an effective approach for fixing skin grafts. Compared with conventional mechanical fixation, NPWT can significantly improve the survival rate and reduce the infection rate of STSG. In the long-term, NPWT can also improve scar surface regularity in the hand, with an esthetic effect that is more satisfactory to clinicians and patients.
C1 [Mo, Ran; Ma, Zhouji; Tan, Qian] Nanjing Med Univ, Dept Burns & Plast Surg, Nanjing Drum Tower Hosp Clin Coll, 321 Zhongshan Rd, Nanjing 210008, Peoples R China.
   [Mo, Ran; Meng, Xueyong; Tan, Qian] Nanjing Univ, Nanjing Drum Tower Hosp, Affiliated Hosp, Dept Burns & Plast Surg,Med Sch, 321 Zhongshan Rd, Nanjing 210008, Peoples R China.
   [Chen, Chen] Nanjing Univ, Dept Nutr, Nanjing Drum Tower Hosp, Affiliated Hosp,Med Sch, Nanjing, Peoples R China.
C3 Nanjing Medical University; Nanjing University; Nanjing University
RP Tan, Q (通讯作者)，Nanjing Med Univ, Dept Burns & Plast Surg, Nanjing Drum Tower Hosp Clin Coll, 321 Zhongshan Rd, Nanjing 210008, Peoples R China.
EM smmutanqian@sina.com
RI Ma, Zhouji/ISB-4061-2023; Chen, Chen/MIQ-8826-2025
OI Ma, Zhouji/0000-0003-1267-0151; 
FU National Natural Science Foundation of China [81800241]; Postgraduate
   Research & Practice Innovation Program of Jiangsu Province
   [SJCX20_0484]; Fundamental Research Funds for the Central Universities
   [14380479]
FX This work was supported by the National Natural Science Foundation of
   China (grant number: 81800241), Postgraduate Research & Practice
   Innovation Program of Jiangsu Province (SJCX20_0484) and the Fundamental
   Research Funds for the Central Universities (14380479).
CR Alkhalil A, 2015, Eplasty, V15, pe29
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NR 28
TC 10
Z9 12
U1 0
U2 11
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2224-5820
EI 2224-5839
J9 ANN PALLIAT MED
JI Ann. Pallliat. Med.
PD MAR
PY 2021
VL 10
IS 3
BP 2935
EP 2947
DI 10.21037/apm-20-1806
PG 13
WC Health Care Sciences & Services
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services
GA RH8MU
UT WOS:000636466300052
PM 33691438
OA gold
DA 2026-07-24
ER

PT J
AU Chiara, O
   Cimbanassi, S
   Biffl, W
   Leppaniemi, A
   Henry, S
   Scalea, TM
   Catena, F
   Ansaloni, L
   Chieregato, A
   de Blasio, E
   Gambale, G
   Gordini, G
   Nardi, G
   Paldalino, P
   Gossetti, F
   Dionigi, P
   Noschese, G
   Tugnoli, G
   Ribaldi, S
   Sgardello, S
   Magnone, S
   Rausei, S
   Mariani, A
   Mengoli, F
   di Saverio, S
   Castriconi, M
   Coccolini, F
   Negreanu, J
   Razzi, S
   Coniglio, C
   Morelli, F
   Buonanno, M
   Lippi, M
   Trotta, L
   Volpi, A
   Fattori, L
   Zago, M
   de Rai, P
   Sammartano, F
   Manfredi, R
   Cingolani, E
AF Chiara, Osvaldo
   Cimbanassi, Stefania
   Biffl, Walter
   Leppaniemi, Ari
   Henry, Sharon
   Scalea, Thomas M.
   Catena, Fausto
   Ansaloni, Luca
   Chieregato, Arturo
   de Blasio, Elvio
   Gambale, Giorgio
   Gordini, Giovanni
   Nardi, Guiseppe
   Paldalino, Pietro
   Gossetti, Francesco
   Dionigi, Paolo
   Noschese, Giuseppe
   Tugnoli, Gregorio
   Ribaldi, Sergio
   Sgardello, Sebastian
   Magnone, Stefano
   Rausei, Stefano
   Mariani, Anna
   Mengoli, Francesca
   di Saverio, Salomone
   Castriconi, Maurizio
   Coccolini, Federico
   Negreanu, Joseph
   Razzi, Salvatore
   Coniglio, Carlo
   Morelli, Francesco
   Buonanno, Maurizio
   Lippi, Monica
   Trotta, Liliana
   Volpi, Annalisa
   Fattori, Luca
   Zago, Mauro
   de Rai, Paolo
   Sammartano, Fabrizio
   Manfredi, Roberto
   Cingolani, Emiliano
TI International consensus conference on open abdomen in trauma
SO JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
LA English
DT Article
DE Trauma; open abdomen; negative-pressure wound therapy; enteric fistula;
   definitive abdominal closure
ID PRESSURE WOUND THERAPY; TEMPORARY ABDOMINAL CLOSURE; VACUUM-ASSISTED
   CLOSURE; DAMAGE-CONTROL LAPAROTOMY; EARLY ENTERAL NUTRITION; PLANNED
   VENTRAL HERNIA; FASCIAL CLOSURE; ENTEROATMOSPHERIC FISTULAS;
   ENTEROCUTANEOUS FISTULAS; COMPARTMENT SYNDROME
AB BACKGROUND A part of damage-control laparotomy is to leave the fascial edges and the skin open to avoid abdominal compartment syndrome and allow further explorations. This condition, known as open abdomen (OA), although effective, is associated with severe complications. Our aim was to develop evidence-based recommendations to define indications for OA, techniques for temporary abdominal closure, management of enteric fistulas, and methods of definitive wall closure.
   METHODS The literature from 1990 to 2014 was systematically screened according to PRISMA [Preferred Reporting Items for Systematic Reviews and Meta-analyses] protocol. Seventy-six articles were reviewed by a panel of experts to assign grade of recommendations (GoR) and level of evidence (LoE) using the GRADE [Grading of Recommendations Assessment, Development, and Evaluation] system, and an international consensus conference was held.
   RESULTS OA in trauma is indicated at the end of damage-control laparotomy, in the presence of visceral swelling, for a second look in vascular injuries or gross contamination, in the case of abdominal wall loss, and if medical treatment of abdominal compartment syndrome has failed (GoR B, LoE II). Negative-pressure wound therapy is the recommended temporary abdominal closure technique to drain peritoneal fluid, improve nursing, and prevent fascial retraction (GoR B, LoE I). Lack of OA closure within 8 days (GoR C, LoE II), bowel injuries, high-volume replacement, and use of polypropylene mesh over the bowel (GoR C, LoE I) are risk factors for frozen abdomen and fistula formation. Negative-pressure wound therapy allows to isolate the fistula and protect the surrounding tissues from spillage until granulation (GoR C, LoE II). Correction of fistula is performed after 6 months to 12 months. Definitive closure of OA has to be obtained early (GoR C, LoE I) with direct suture, traction devices, component separation with or without mesh. Biologic meshes are an option for wall reinforcement if bacterial contamination is present (GoR C, LoE II).
   CONCLUSION OA and negative-pressure techniques improve the care of trauma patients, but closure must be achieved early to avoid complications. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.)
C1 [Chiara, Osvaldo; Cimbanassi, Stefania; Sgardello, Sebastian; Mariani, Anna; Lippi, Monica; Trotta, Liliana; Sammartano, Fabrizio] Osped Niguarda Ca Granda, Ctr Trauma, Trauma Surg & Intens Care, Parma, Italy.
   [Negreanu, Joseph] Osped Niguarda Ca Granda, Wound Healing Serv, Parma, Italy.
   [de Rai, Paolo] Policlin Hosp, Gen & Emergency Surg, Milan, Italy.
   [Catena, Fausto; Volpi, Annalisa] Parma Hosp, Emergency Surg & Intens Care, Parma, Italy.
   [Catena, Fausto; Ansaloni, Luca; Magnone, Stefano; Manfredi, Roberto] Papa Giovanni XXIII Hosp, Gen Surg, Bergamo, Italy.
   [Zago, Mauro] Policlin S Pietro Hosp, Gen Surg, Bergamo, Italy.
   [Chieregato, Arturo] Careggi Hosp, Neurosurg Orthoped Anesthesia & Intens Care, Florence, Italy.
   [de Blasio, Elvio; Buonanno, Maurizio] Rummo Hosp, Gen & Emergency Surg & Intens Care, Benvento, Italy.
   [Gambale, Giorgio] Bufalini Hosp, Intens Care, Cesena, Italy.
   [Gordini, Giovanni; Tugnoli, Gregorio; Mengoli, Francesca; di Saverio, Salomone; Coniglio, Carlo] Maggiore Hosp, Trauma Surg & Intens Care, Bologna, Italy.
   [Nardi, Guiseppe; Cingolani, Emiliano] San Camillo Hosp, Shock & Trauma Serv, Rome, Italy.
   [Gossetti, Francesco; Ribaldi, Sergio] Umberto 1 Hosp, Gen Surg, Rome, Italy.
   [Paldalino, Pietro; Fattori, Luca] San Gerardo Hosp, Gen Surg, Monza, Italy.
   [Dionigi, Paolo] San Matteo Hosp, Gen Surg, Pavia, Italy.
   [Nardi, Guiseppe] Cardarelli Hosp, Trauma Surg, Naples, Italy.
   [Castriconi, Maurizio] Cardarelli Hosp, Gen Surg, Naples, Italy.
   [Ribaldi, Sergio] Insubria Univ, Dept Surg, Varese, Italy.
   [Rausei, Stefano] Umberto Parini Hosp, Emergency Surg, Aosta, Italy.
   [Biffl, Walter] Denver Hlth Med Ctr, Trauma & Acute Care Surg, Denver, CO USA.
   [Henry, Sharon; Scalea, Thomas M.] R Adams Cowley Shock Trauma Ctr, Baltimore, MD USA.
   [Leppaniemi, Ari] Meilahti Hosp, Dept Surg, Emergency Surg, Helsinki, Finland.
C3 Ospedale Niguarda Ca' Granda; Ospedale Niguarda Ca' Granda; University
   of Parma; University Hospital of Parma; ASST Papa Giovanni XXIII;
   University of Florence; Azienda Ospedaliero Universitaria Careggi; AUSL
   di Bologna; Sapienza University Rome; University Hospital Sapienza Rome;
   San Gerardo Hospital; IRCCS Fondazione San Matteo; Antonio Cardarelli
   Hospital; Antonio Cardarelli Hospital; University of Insubria; Azienda
   USL della Valle d'Aosta; Denver Health Medical Center; University System
   of Maryland; University of Maryland Baltimore; University of Helsinki;
   Helsinki University Central Hospital
RP Scalea, TM (通讯作者)，22 S Greene St, Baltimore, MD 21201 USA.
EM tscalea@umm.edu
RI Di Saverio, Salomone/G-1437-2012; Leppäniemi, Ari/GQZ-7991-2022; Volpi,
   Annalisa/AHH-5394-2022; Magnone, Stefano/R-6719-2016; Gordini,
   Giovanni/AAB-8170-2022; henry, sharon/JXY-5017-2024; chiara,
   osvaldo/R-6151-2018; Zago, Mauro/O-3387-2015; Dionigi,
   Gianlorenzo/R-4381-2017; Ansaloni, Luca/AAJ-6507-2020; Coccolini,
   Federico/AAJ-6507-2020; coniglio, carlo/AAB-7128-2022; Ansaloni,
   Luca/AAP-9134-2020; Rausei, Stefano/AAM-7898-2021
OI Volpi, Annalisa/0000-0001-5337-9155; Magnone,
   Stefano/0000-0002-8001-3754; chiara, osvaldo/0000-0003-2409-2109; Zago,
   Mauro/0000-0001-9322-0798; Ansaloni, Luca/0000-0001-6427-0307;
   Coccolini, Federico/0000-0001-6364-4186; coniglio,
   carlo/0000-0002-8207-0525; Chieregato, Arturo/0000-0001-6690-8597;
   Sammartano, Fabrizio/0000-0003-4781-0687; Ansaloni,
   Luca/0000-0001-6427-0307; 
FU American Association for the Surgery of Trauma (AAST); Associazione
   Chirurghi Ospedalieri Italiani (ACOI)
FX This study was endorsed by the Trauma Update Network (TUN), European
   Society of Trauma and Emergency Surgery (ESTES), World Society of
   Emergency Surgery (WSES), Societa' Italiana di Anestesia, Analgesia
   Rianimazione e Terapia Intensiva (SIARTI), Societa' Italiana di
   Chirurgia d'Urgenza e del Trauma (SICUT), Societa' Lombarda di Chirurgia
   (SLC), Italian Society of Hernia and Abdominal Wall Surgery (ISHAWS),
   and International Disaster Medicine Association (IDMA). It is also
   supported by representatives of American Association for the Surgery of
   Trauma (AAST), Associazione Chirurghi Ospedalieri Italiani (ACOI).
CR Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
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NR 79
TC 74
Z9 92
U1 0
U2 25
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 2163-0755
EI 2163-0763
J9 J TRAUMA ACUTE CARE
JI J. Trauma Acute Care Surg.
PD JAN
PY 2016
VL 80
IS 1
BP 173
EP 183
DI 10.1097/TA.0000000000000882
PG 11
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Surgery
GA DA1GN
UT WOS:000367544400026
PM 27551925
DA 2026-07-24
ER

PT J
AU Adogwa, O
   Fatemi, P
   Perez, E
   Moreno, J
   Gazcon, GC
   Gokaslan, ZL
   Cheng, J
   Gottfried, O
   Bagley, CA
AF Adogwa, Owoicho
   Fatemi, Parastou
   Perez, Edgar
   Moreno, Jessica
   Gazcon, Gustavo Chagoya
   Gokaslan, Ziya L.
   Cheng, Joseph
   Gottfried, Oren
   Bagley, Carlos A.
TI Negative pressure wound therapy reduces incidence of postoperative wound
   infection and dehiscence after long-segment thoracolumbar spinal fusion:
   a single institutional experience
SO SPINE JOURNAL
LA English
DT Article
DE Negative pressure wound therapy; Deformity; Wound dehiscence; Wound
   infection; Spine outcomes; Surgical site infections
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED CONTROLLED-TRIAL; LUMBAR SPINE;
   SURGERY; DUROTOMY; MULTICENTER; PREVENTION; ULCERS; STATE
AB BACKGROUND CONTEXT: Wound dehiscence and surgical site infections (SSIs) can have a profound impact on patients as they often require hospital readmission, additional surgical interventions, lengthy intravenous antibiotic administration, and delayed rehabilitation. Negative pressure wound therapy (NPWT) exposes the wound site to negative pressure, resulting in the improvement of blood supply, removal of excess fluid, and stimulation of cellular proliferation of granulation tissue.
   PURPOSE: To assess the incidence of wound infection and dehiscence in patients undergoing long-segment thoracolumbar fusion before and after the routine use of NPWT.
   STUDY DESIGN: Retrospective study.
   PATIENT SAMPLE: One hundred sixty patients undergoing long-segment thoracolumbar spine fusions were included in this study.
   OUTCOME MEASURES: Postoperative incidence of wound infection and dehiscence.
   METHODS: All adult patients undergoing thoracolumbar fusion for spinal deformity over a 6-year period at Duke University Medical Center by the senior author (CB) were included in this study. In 2012, a categorical change was made by the senior author (CB) that included the postoperative routine use of incisional NPWT devices after primary wound closure in all long-segment spine fusions. Before 2012, NPWT was not used. After primary wound closure, a negative pressure device is contoured to the size of the incision and placed over the incision site for 3 postoperative days. We retrospectively review the first 46 cases in which NPWT was used and compared them with the immediately preceding 114 cases to assess the incidence of wound infection and dehiscence.
   RESULTS: One hundred sixty (NPWT: 46 cases, non-NPWT: 114 cases) long-segment thoracolumbar spine fusions were performed for deformity correction. Baseline characteristics were similar between both cohorts. Compared with the non-NPWT cohort, a 50% decrease in the incidence of wound dehiscence was observed in the NPWT patient cohort (6.38% vs. 12.28%, p=.02). Similarly, compared with the non-NPWT cohort, the incidence of postoperative SSIs was significantly decreased in the NPWT cohort (10.63% vs. 14.91%, p=.04).
   CONCLUSIONS: Routine use of incisional NPWT was associated with a significant reduction in the incidence of postoperative wound infection and dehiscence. (C) 2014 Elsevier Inc. All rights reserved.
C1 [Adogwa, Owoicho; Fatemi, Parastou; Perez, Edgar; Moreno, Jessica; Gazcon, Gustavo Chagoya; Gottfried, Oren; Bagley, Carlos A.] Duke Univ, Med Ctr, Div Neurosurg, Durham, NC 27710 USA.
   [Gokaslan, Ziya L.] Johns Hopkins Univ, Sch Med, Dept Neurosurg, Baltimore, MD USA.
   [Cheng, Joseph] Vanderbilt Univ, Med Ctr, Dept Neurosurg, Nashville, TN 37232 USA.
C3 Duke University; Johns Hopkins University; Vanderbilt University
RP Adogwa, O (通讯作者)，DUMC, Box 3807, Durham, NC 27710 USA.
EM owoicho.adogwa@gmail.com
RI Moreno, Jessica/AAV-1030-2021; Chagoya, Gustavo/S-8172-2019
OI Chagoya, Gustavo/0000-0002-8337-4467
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NR 24
TC 89
Z9 96
U1 0
U2 19
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1529-9430
EI 1878-1632
J9 SPINE J
JI Spine Journal
PD DEC
PY 2014
VL 14
IS 12
BP 2911
EP 2917
DI 10.1016/j.spinee.2014.04.011
PG 7
WC Clinical Neurology; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Orthopedics
GA AU2EQ
UT WOS:000345429500020
PM 24769401
DA 2026-07-24
ER

PT J
AU Escobar-Vidarte, MF
   Messa, A
   Nieto, AJ
   Echavarría, MP
   Carvajal, JA
   Fernández, PA
AF Fernanda Escobar-Vidarte, Maria
   Messa, Adriana
   Jose Nieto, Albaro
   Paula Echavarria, Maria
   Andres Carvajal, Javier
   Andrea Fernandez, Paula
TI Use of Negative Pressure Wound Therapy in Surgical Site Infection During
   Pregnancy A Case Study
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Negative pressure wound therapy; Pregnancy; Surgical site infection;
   Wound infection; Wound management
ID CESAREAN-SECTION; HIGH-RISK; COMPLICATIONS
AB BACKGROUND: Surgical site infections (SSIs) are a known cause of morbidity and mortality; however, evidence related to management of SSIs during pregnancy is sparse. CASE: A 26-year-old female patient with an adnexal cystic lesion underwent laparotomy at 19 weeks of pregnancy. She experienced a late SSI 10 days after initial surgery, necessitating surgical debridement. She was treated with multiple surgical interventions for wound irrigations and wound closure assisted by a negative pressure wound therapy. CONCLUSION: Negative pressure wound therapy was used for treatment of an SSI during pregnancy without causing premature delivery or requiring a cesearan section.
C1 [Fernanda Escobar-Vidarte, Maria; Messa, Adriana; Jose Nieto, Albaro; Paula Echavarria, Maria; Andres Carvajal, Javier] Fdn Clin Valle Del Lili, Dept Gynecol & Obstet, Cali, Colombia.
   [Andrea Fernandez, Paula] Fdn Clin Valle del Lili, Clin Invest Ctr, Cali, Colombia.
RP Escobar-Vidarte, MF (通讯作者)，Fdn Clin Valle de Lili, Dept Gynecol & Obstet, Carrera 98 18-49, Cali, Colombia.
EM mayaev@hotmail.com
RI Nieto-Calvache, Albaro/AAJ-8485-2021; Escobar-Vidarte, María
   F/R-7501-2016
OI Escobar-Vidarte, María F/0000-0002-1441-0890
CR Anglim B, 2015, J OBSTET GYNAECOL, V35, P255, DOI 10.3109/01443615.2014.958442
   [Anonymous], 2016, National and state healthcare associated infections progress report
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   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Echebiri NC, 2015, OBSTET GYNECOL, V125, P299, DOI 10.1097/AOG.0000000000000634
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   Young CNJ, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000005397
NR 17
TC 1
Z9 1
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD SEP-OCT
PY 2019
VL 46
IS 5
BP 453
EP 456
DI 10.1097/WON.0000000000000573
PG 4
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA IZ3ZY
UT WOS:000487025300014
PM 31513134
DA 2026-07-24
ER

PT J
AU Kirsner, R
   Dove, C
   Reyzelman, A
   Vayser, D
   Jaimes, H
AF Kirsner, Robert
   Dove, Cyaandi
   Reyzelman, Alex
   Vayser, Dean
   Jaimes, Henry
TI A prospective, randomized, controlled clinical trial on the efficacy of
   a single-use negative pressure wound therapy system, compared to
   traditional negative pressure wound therapy in the treatment of chronic
   ulcers of the lower extremities
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; EVIDENCE-BASED
   RECOMMENDATIONS; LEG ULCERS; MANAGEMENT; MULTICENTER; COMPRESSION;
   DRESSINGS; STEPS; NPWT
AB Multicenter, phase-4, randomized, comparative-efficacy study in patients with VLUs or DFUs comparing for noninferiority the percentage change in target ulcer dimensions (area, depth, and volume) a single-use negative pressure wound therapy (s-NPWT) system versus traditional NPWT (t-NPWT) over a 12-week treatment period or up to confirmed healing. Baseline values were taken at the randomization visit. Randomized by wound type and size, 164 patients with non-infected DFUs and VLUs were included. The ITT population was composed of 161 patients (101 with VLUs, 60 with DFUs) and 115 patients completed follow-up (64 in the s-NPWT group and 51 in the t-NPWT group) (PP population). The average age for all patients was 61.5 years, 36.6% were women, and treatment groups were statistically similar at baseline. Primary endpoint analyses on wound area reduction demonstrated statistically significant reduction in favor of s-NPWT (p = 0.003) for the PP population and for the ITT population (p < 0.001). Changes in wound depth (p = 0.018) and volume (p = 0.013) were also better with s-NPWT. Faster wound closure was observed with s-NPWT (Cox Proportional Hazards ratio (0.493 (0.273, 0.891); p = 0.019) in the ITT population. Wound closure occurred in 45% of patients in the s-NPWT group vs. 22.2% of patients in the t-NPWT group (p = 0.002). Median estimate of the time to wound closure was 77 days for s-NPWT. No estimate could be provided for t-NPWT due to the low number of patients achieving wound closure. Device-related AEs were more frequent in the t-NPWT group (41 AEs from 29 patients) than in the s-NPWT group (16 AEs from 12 patients). The s-NPWT system met noninferiority and achieved statistical superiority vs. t-NPWT in terms of wound progression toward healing over the treatment period. When NPWT is being considered for the management of challenging VLUs and DFUs, s-NPWT should be considered a first choice over other types of NPWT.
C1 [Kirsner, Robert] Univ Miami, Miller Sch Med, Dr Phillip Frost Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA.
   [Dove, Cyaandi] Adv Foot & Ankle Ctr, Las Vegas, NV USA.
   [Reyzelman, Alex] Samuel Merritt Univ, Calif Sch Podiatr Med, Dept Med, San Francisco, CA USA.
   [Reyzelman, Alex] UCSF Ctr Limb Preservat, San Francisco, CA USA.
   [Vayser, Dean] Foot & Ankle Ctr, Dept Orthoped, Scripps Clin Med Grp, Wound Care Div, San Diego, CA USA.
   [Jaimes, Henry] Wounds Smith & Nephew, London, England.
C3 University of Miami; Samuel Merritt University
RP Kirsner, R (通讯作者)，Univ Miami, Miller Sch Med, 1321 NW 14th St,Room 504, Miami, FL 33125 USA.; Jaimes, H (通讯作者)，Hatters Lane,Bldg 5,Croxley Pk, Watford WD18 8YE, England.
EM rkisner@med.miami.edu; henry.jaimes@smith-nephew.com
OI Jaimes, Henry/0000-0001-6526-1963
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NR 40
TC 31
Z9 41
U1 0
U2 17
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD SEP
PY 2019
VL 27
IS 5
BP 519
EP 529
DI 10.1111/wrr.12727
PG 11
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA IY0GP
UT WOS:000486070300010
PM 31087729
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Frear, CC
   Griffin, B
   Cuttle, L
   McPhail, SM
   Kimble, R
AF Frear, Cody C.
   Griffin, Bronwyn
   Cuttle, Leila
   McPhail, Steven M.
   Kimble, Roy
TI Study of negative pressure wound therapy as an adjunct treatment for
   acute burns in children (SONATA in C): protocol for a randomised
   controlled trial
SO TRIALS
LA English
DT Article
DE Paediatric; Burns; Negative-pressure Wound Therapy;
   Re-epithelialisation; Pain; Burn wound progression; Itch; Randomised
   controlled trial
ID VACUUM-ASSISTED CLOSURE; PARTIAL-THICKNESS BURNS; SCAR ASSESSMENT SCALE;
   PEDIATRIC BURNS; SKIN-GRAFTS; SUBATMOSPHERIC PRESSURE; PAIN INTENSITY;
   CLINICAL-TRIAL; THERMAL-INJURY; MANAGEMENT
AB Although negative pressure wound therapy (NPWT) is widely used in the management of several wound types, its efficacy as a primary therapy for acute burns has not yet been adequately investigated, with research in the paediatric population particularly lacking. There is limited evidence, however, that NPWT might benefit children with burns, amongst whom scar formation, wound progression and pain continue to present major management challenges. The purpose of this trial is to determine whether NPWT in conjunction with standard therapy accelerates healing, reduces wound progression and decreases pain more effectively than standard treatment alone.
   A total of 104 children will be recruited for this trial. To be eligible, candidates must be under 17 years of age and present to the participating children's hospital within 7 days of their injury with a thermal burn covering < 5% of their total body surface area. Facial and trivial burns will be excluded. Following a randomised controlled parallel design, participants will be allocated to either an active control or intervention group. The former will receive standard therapy consisting of Acticoat (TM) and Mepitel (TM). The intervention arm will be treated with silver-impregnated dressings in addition to NPWT via the RENASYS TOUCH (TM) vacuum pump. Participants' dressings will be changed every 3 to 5 days until their wounds are fully re-epithelialised. Time to re-epithelialisation will be studied as the primary outcome. Secondary outcomes will include pain, pruritus, wound progression, health-care-resource use (and costs), ease of management, treatment satisfaction and adverse events. Wound fluid collected during NPWT will also be analysed to generate a proteomic profile of the burn microenvironment.
   The study will be the first randomised controlled trial to explore the clinical effects of NPWT on paediatric burns, with the aim of determining whether the therapy warrants implementation as an adjunct to standard burns management.
   Australian New Zealand Clinical Trials Registry, Registered on 16 February 2018.
C1 [Frear, Cody C.; Griffin, Bronwyn; Kimble, Roy] Univ Queensland, Ctr Childrens Burns & Trauma Res, Childrens Hlth Res Ctr, Level 7,62 Graham St, South Brisbane, Qld 4101, Australia.
   [Frear, Cody C.; Griffin, Bronwyn; Kimble, Roy] Queensland Childrens Hosp, Pegg Leditschke Childrens Burns Ctr, Lvl 5,501 Stanley St, South Brisbane, Qld 4101, Australia.
   [Frear, Cody C.; Griffin, Bronwyn; Kimble, Roy] Univ Queensland, Fac Med, 288 Herston Rd, Brisbane, Qld 4006, Australia.
   [Cuttle, Leila] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Ctr Childrens Burns & Trauma Res, Childrens Hlth Res Ctr, Lvl 8, South Brisbane, Qld 4101, Australia.
   [McPhail, Steven M.] Queensland Hlth, Metro South Hlth, Ctr Functioning & Hlth Res, Brisbane, Qld 4102, Australia.
   [McPhail, Steven M.] Queensland Univ Technol, Sch Publ Hlth & Social Work, Brisbane, Qld 4059, Australia.
   [McPhail, Steven M.] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia.
C3 University of Queensland; Childrens Health Queensland Hospital & Health
   Service; Queensland Childrens Hospital; University of Queensland;
   Queensland University of Technology (QUT); Queensland Health; Queensland
   University of Technology (QUT); Queensland University of Technology
   (QUT)
RP Frear, CC (通讯作者)，Univ Queensland, Ctr Childrens Burns & Trauma Res, Childrens Hlth Res Ctr, Level 7,62 Graham St, South Brisbane, Qld 4101, Australia.; Frear, CC (通讯作者)，Queensland Childrens Hosp, Pegg Leditschke Childrens Burns Ctr, Lvl 5,501 Stanley St, South Brisbane, Qld 4101, Australia.
EM cody.frear@uqconnect.edu.au
RI Cuttle, Leila/U-9376-2017; McPhail, Steven/JMR-2141-2023; Kimble,
   Roy/B-4160-2011; Griffin, Bronwyn/AEB-6299-2022
OI Cuttle, Leila/0000-0002-2282-4815; McPhail, Steven/0000-0002-1463-662X;
   Frear, Cody/0000-0002-6011-2472; Griffin, Bronwyn/0000-0002-6182-9125
FU Smith Nephew; National Health and Medical Research Council (Australian
   government) fellowship
FX Funding for this study has been provided by Smith & Nephew in the form
   of a research grant awarded to the Queensland University of Technology.
   Smith & Nephew's contact details: Namal Nawana (CEO), London, United
   Kingdom and Kingston upon Hull, United Kingdom. SMM is supported by a
   National Health and Medical Research Council (Australian government)
   fellowship.
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   ,, 2008, The global burden of disease: 2004 update
NR 142
TC 14
Z9 18
U1 0
U2 13
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1745-6215
J9 TRIALS
JI Trials
PD FEB 13
PY 2019
VL 20
AR 130
DI 10.1186/s13063-019-3223-9
PG 15
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Research & Experimental Medicine
GA HL7OC
UT WOS:000458929900003
PM 30760332
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ali, E
   Raghuvanshi, M
AF Ali, E.
   Raghuvanshi, M.
TI Treatment of open upper limb injuries with infection prevention and
   negative pressure wound therapy: a systematic review
SO JOURNAL OF WOUND CARE
LA English
DT Review
DE infection; negative pressure wound therapy; upper limb injuries; vacuum
   dressing
ID VACUUM-ASSISTED CLOSURE; LOCAL ANTIBIOTIC-THERAPY; VAC(R) THERAPY; BEAD
   POUCH; MANAGEMENT; FRACTURES; DELIVERY; COVERAGE; LESSONS
AB Objective: Open upper limb injuries requiring soft reconstruction can pose a dilemma for trauma surgeons when considering the treatment options. The British Orthopaedic Association and British Association of Plastic, Reconstructive and Aesthetic Surgeons Standard for Trauma (BOAST) have addressed the management of severe open lower limb fractures with the creation of the BOAST 4 guidelines. However, no such gold standard exists for the treatment of open injuries of the upper limb. Furthermore, treatment of these injuries is often more difficult and requires complicated strategies. Since the advent of negative pressure wound therapy (NPWT), there has been an improvement in wound care, though a focused review of its use in wound closure and infection prevention in the upper limb has not been published. We examine wound care management for open upper limb injuries with regard to the dressings applied, NPWT, wound closure and infection prevention.
   Method: A systematic search of Medline, Cochrane and Google Scholar was performed using the key words. The key word searches were performed by two independent reviewers and 8,792 papers were found. Manuscripts between 1990 and 2010 were included, with the addition of key manuscripts before this date. Each manuscript was assessed by the two authors independently for methodology and validity
   Results: Approximately 120 manuscripts fulfilled selection criteria examining the influence of NPWT on open upper and lower limb injuries, and those examining infection risk in the same injuries. Of these 120 manuscripts, 28 were suitable for inclusion in the review. The systematic review is presented, allied to the BOAST 4 principles, examining the use of NPWT and the tools available for infection prevention for wounds of the upper and lower limb. The use of NPWT in conjunction with antibiotic-bead therapy improved the way in which open fractures of both the upper and lower limb are treated.
   Conclusion: Production of guidelines is warranted for the treatment of upper limb injuries. The treatment options available for wound closure and infection prevention that are used in the treatment of open injuries of the lower limb could be adopted to open injuries of the upper limb.
C1 [Ali, E.] Univ Cambridge, Magdalene Coll, Clin Sch, Cambridge, England.
   [Raghuvanshi, M.] Broomfield Hosp, Chelmsford, England.
C3 University of Cambridge; Mid Essex Hospital Services NHS Trust;
   Broomfield Hospital
RP Ali, E (通讯作者)，Univ Cambridge, Magdalene Coll, Clin Sch, Cambridge, England.
EM ea389@cam.ac.uk
CR [Anonymous], JUST ILLUSION PLAST
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NR 29
TC 2
Z9 5
U1 0
U2 8
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD DEC
PY 2017
VL 26
IS 12
BP 712
EP 719
DI 10.12968/jowc.2017.26.12.712
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA FQ2LG
UT WOS:000418187400003
PM 29244969
DA 2026-07-24
ER

PT J
AU Chen, L
   Li, GR
   Liu, S
   Ma, XJ
   Li, XY
   Su, YJ
   Guo, SZ
AF Chen, Lin
   Li, Guorui
   Liu, Sha
   Ma, Xianjie
   Li, Xueyong
   Su, Yingjun
   Guo, Shuzhong
TI Comparison of Negative Pressure Wound Therapy and Conventional Therapy
   for Cranial Bone-exposed Wounds in Rabbits
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE cranial bone-exposed wound; negative pressure wound therapy; periosteum;
   wound healing
ID VACUUM-ASSISTED CLOSURE; TISSUE BLAST INJURY; MICROVESSEL DENSITY; SWINE
   MODEL; EXPRESSION; PERIOSTEUM; FRACTURES; DEFECTS; FLAPS
AB Background: Bone-exposed wounds with intact or defected periosteum are difficult to heal. To provide relevant experimental evidence for guidance of clinical therapy, we established a rabbit model to compare the efficacies of negative pressure wound therapy (NPWT) and conventional guaze dressing therapy on the healing of cranial bone-exposed wounds.
   Methods: Full-thickness excisional circular wounds of 2.0 cm in diameter with exposed bones covered with or without periosteum were created at the parietal regions in 88 rabbits that were further randomly divided into the following treatment groups: periosteum-intact wounds treated with conventional vaseline gauze dressings (P + Control group), periosteum-intact wounds treated with NPWT (P + NPWT group), periosteum-lacking wounds treated with conventional vaseline gauze dressings (P-Control group), and periosteum-lacking wounds treated with NPWT (P-NPWT group). The wounds of NPWT groups were treated using a negative pressure therapy assembly that was set at a continuous pressure of -125 mm Hg for 7 days, then covered with vaseline gauze. The wound healing rates, wound infection rates, hydroxyproline content, and wound tissue histology were determined and evaluated.
   Results: The NPWT shortened the wound healing time by approximately 5 days when compared with the conventional gauze therapy. The histological characterization of wound tissues showed that NPWT decreased the inflammatory cells infiltration, accelerated reepithelialization and facilitated the organization of collagen fibers into neat layers on postoperative day (POD) 10. The NPWT enhanced bacterial clearances, reduced infection rates and increased the hydroxyproline contents in both types of wounds on PODs 10 and 15. The immunohistochemical staining of CD31 showed the NPWT treatment resulted in a significantly increased and persistent angiogenesis, and the wounds treated with NPWT showed well developed and more functional vessels at POD 7 compared with control.
   Conclusions: The NPWT is a more effective therapy for bone-exposed wounds than conventional guaze dressing therapy. The NPWT can promote bone-exposed wounds healing by increasing collagen contents and vessels densities while reducing inflammatory cells infiltration, reducing wound infection rates, and inducing an ordered collagen arrangement.
C1 [Chen, Lin; Li, Guorui; Liu, Sha; Ma, Xianjie; Su, Yingjun; Guo, Shuzhong] Fourth Mil Med Univ, Xijing Hosp, Dept Plast & Reconstruct Surg, 15 Changle West Rd, Xian 710032, Shaanxi, Peoples R China.
   [Li, Guorui] Chinese Peoples Liberat Army, Hosp 25, Dept Burns & Plast Surg, Xian, Shaanxi, Peoples R China.
   [Li, Xueyong] Fourth Mil Med Univ, Tangdu Hosp, Dept Plast Surg, Xian, Shaanxi, Peoples R China.
C3 Air Force Medical University; Air Force Medical University
RP Su, YJ; Guo, SZ (通讯作者)，Fourth Mil Med Univ, Xijing Hosp, Dept Plast & Reconstruct Surg, 15 Changle West Rd, Xian 710032, Shaanxi, Peoples R China.
EM xjzxwka@fmmu.edu.cn; xjzxwkb@fmmu.edu.cn
RI Chen, Lin/JKH-5087-2023; /AAI-1694-2020
OI Chen, Lin/0000-0002-0586-7098; 
FU Shaanxi Provincial Science and Technology Innovation Project
   [2015KTTSGY01-06]; Clinical Innovative Technique Grant of PLA
   [2010gxjs079]
FX This study was supported by Shaanxi Provincial Science and Technology
   Innovation Project (2015KTTSGY01-06) and Clinical Innovative Technique
   Grant of PLA (2010gxjs079).
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NR 43
TC 7
Z9 7
U1 1
U2 15
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD OCT
PY 2017
VL 79
IS 4
BP 397
EP 403
DI 10.1097/SAP.0000000000001074
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FG8DU
UT WOS:000410659400017
PM 28816717
DA 2026-07-24
ER

PT J
AU Fraccalvieri, M
   Ruka, E
   Bocchiotti, MA
   Zingarelli, E
   Bruschi, S
AF Fraccalvieri, Marco
   Ruka, Erind
   Bocchiotti, Maria Alessandra
   Zingarelli, Enrico
   Bruschi, Stefano
TI Patient's pain feedback using negative pressure wound therapy with foam
   and gauze
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Foam; Gauze; Negative pressure wound therapy; NPWT; Pain
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED CONTROLLED-TRIAL; EXPERIENCE; STATE;
   ART
AB Wounds can be caused by different mechanisms and have a significant morbidity and mortality. Negative pressure wound therapy (NPWT) is one of the most successful treatment modalities for wound healing. We have been using both foam and gauze-based NPWT. During application of NPWT, we noticed that the patient's pain was of varying intensity depending on the filler used. The aim of our work was to compare the level of pain and feedback before, during the treatment and at the dressing change after treatment with NPWT with two different fillers. For this study, we compared a pool of 13 gauze-treated patients with a pool of 18 foam-treated patients regarding the level of pain and feedback before, during the treatment and at the dressing change after treatment with NPWT. They were all post-traumatic patients with loss of tissue up to the muscular band. The patients were asked to respond to a questionnaire interviewed by the same physician to assess the level of pain using VNS (verbal numerical scale). We observed similar difference of means before and during the treatment with NPWT with gauze and foam. Regarding the pain at the dressing change, the mean of the scores for the foam was 6.5 while for the gauze was 4.15. In this case, we noticed the most significant difference between means from the scores given: 2.35 which was a statistically significant difference between the two groups (P = 0.046). The finding of this study confirms less pain at the dressing change after treatment with gauze-based NPWT. In our opinion, this finding is related to the more adhesive property of the foam probably because of the ingrowth of the granulation tissue in the micropores present on the foam. Considering this statement, we recommend the foam for neuropathic and paraplegic patients and the gauze for patients with bone and tendon exposition wounds, patients that do not tolerate NPWT with foam and low compliant patient particularly paediatric and old-age patients. We remind that the performance of this study was not sponsored by any company.
C1 [Fraccalvieri, Marco; Ruka, Erind; Bocchiotti, Maria Alessandra; Zingarelli, Enrico; Bruschi, Stefano] Univ Turin, Dept Reconstruct & Aesthet Plast Surg, San Giovanni Battista Hosp, Turin, Italy.
C3 University of Turin; A.O.U. Citta della Salute e della Scienza di
   Torino; AOU San Giovanni Battista-Molinette
RP Fraccalvieri, M (通讯作者)，Univ Turin, Dept Reconstruct & Aesthet Plast Surg, San Giovanni Battista Hosp, Turin, Italy.
EM marco@fraccalvieri.it
RI /AAF-4387-2019
OI Bruschi, Stefano/0000-0002-4746-9864; Bocchiotti, Maria
   Alessana/0000-0003-0723-1074
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NR 19
TC 35
Z9 41
U1 0
U2 12
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1742-4801
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2011
VL 8
IS 5
BP 492
EP 499
DI 10.1111/j.1742-481X.2011.00821.x
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 822EG
UT WOS:000295026100009
PM 21827628
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Li, HZ
   Xu, XH
   Wang, DW
   Lin, YM
   Lin, N
   Lu, HD
AF Li, Hui-Zi
   Xu, Xiang-He
   Wang, Da-Wei
   Lin, Yi-Ming
   Lin, Nan
   Lu, Hua-Ding
TI Negative pressure wound therapy for surgical site infections: a
   systematic review and meta-analysis of randomized controlled trials
SO CLINICAL MICROBIOLOGY AND INFECTION
LA English
DT Review
DE Meta-analysis; Negative-pressure wound therapy; Randomized controlled
   trials; Surgical wound infection; Systematic review
ID VACUUM-ASSISTED CLOSURE; OBESE WOMEN; CESAREAN DELIVERY; OPEN FRACTURE;
   PRIMARY HIP; RISK-FACTOR; LOWER-LIMB; GUIDELINES; INCISION; QUALITY
AB Objectives: Previous studies showed the effectiveness of negative pressure wound therapy (NPWT) in preventing surgical site infections (SSIs), but current guidelines do not recommend its routine use for surgical wounds. The aim was to compare the effectiveness and safety of NPWT with standard surgical dressing or conventional therapy for preventing SSIs.
   Methods: Pubmed, Embase and the Cochrane Library were systematically searched on 10 April 2019. Also, we searched clinicaltrials.gov and references of relevant studies. Eligibility criteria were randomized controlled trials (RCTs) and adult surgical patients were included. The effectiveness of NPWT versus standard surgical dressing or conventional therapy was investigated. Relative risks (RRs) and mean differences (MDs) with 95% confidence intervals (CIs) were used to estimate the pooled effect of dichotomous outcomes and continuous outcomes respectively. The primary outcome was surgical site infections. The quality of included studies and the certainty of the evidence were assessed using the risk of bias tool and the GRADE approach.
   Results: A total of 45 RCTs with 6624 surgical patients were included. NPWT reduced SSIs (RR 0.58; 95% CI 0.49-0.69) and wound dehiscence(17 RCTs; RR 0.80; 95% CI 0.65-1.00). NPWT did not increase the risk of hematoma (9 RCTs; RR 0.91; 95% CI 0.40-2.07) and hospital readmission(9 RCTs; RR 0.77; 95% CI 0.52-1.12) or prolong length of hospital stay(15 RCTs; MD -0.38; 95% CI, -0.78 to 0.02). NPWT significantly increased the risk of all adverse event-related outcomes (10 RCTs; RR 3.21; 95% CI, 1.17-8.78). The level of certainty was identified as low for the primary outcome and very low for all the secondary outcomes.
   Conclusions: Compared with standard wound care, NPWT may reduce the risk of SSIs. We are uncertain whether NPWT reduces or increases the risk of wound dehiscence, haematoma, hospital readmission and all adverse event-related outcomes or if it shortens or prolongs length of hospital stay. (C) 2019 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
C1 [Li, Hui-Zi; Xu, Xiang-He; Wang, Da-Wei; Lin, Yi-Ming; Lin, Nan; Lu, Hua-Ding] Sun Yat Sen Univ, Affiliated Hosp 5, Dept Orthopaed, Zhuhai 519000, Guangdong, Peoples R China.
C3 Sun Yat Sen University
RP Lu, HD (通讯作者)，Sun Yat Sen Univ, Affiliated Hosp 5, Dept Orthopaed, Zhuhai 519000, Guangdong, Peoples R China.
EM johnniehuading@163.com
RI Wang, Dawei/HGE-1446-2022
FU National Natural Science Foundation of China [81772384, 81572174]
FX This study was supported by grants from the National Natural Science
   Foundation of China (nos. 81772384 and 81572174). The funders had no
   role in the study design, data collection and analysis, decision to
   publish, or preparation of the manuscript. All the authors do not have
   conflict of interests to declare.
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NR 90
TC 46
Z9 53
U1 0
U2 16
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1198-743X
EI 1469-0691
J9 CLIN MICROBIOL INFEC
JI Clin. Microbiol. Infect.
PD NOV
PY 2019
VL 25
IS 11
BP 1328
EP 1338
DI 10.1016/j.cmi.2019.06.005
PG 11
WC Infectious Diseases; Microbiology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Microbiology
GA JH3QX
UT WOS:000492683600007
PM 31220604
DA 2026-07-24
ER

PT J
AU Cheng, HT
   Hsu, YC
   Wu, CI
AF Cheng, Hsu-Tang
   Hsu, Yung-Chang
   Wu, Chao-I
TI Efficacy and safety of negative pressure wound therapy for Szilagyi
   grade III peripheral vascular graft infection
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Review; Negative pressure wound therapy; Vascular surgical procedures;
   Surgical wound
ID VACUUM-ASSISTED CLOSURE; GROIN
AB A best evidence topic in vascular surgery was written according to a structured protocol. The question addressed was whether it is safe and effective to use negative pressure wound therapy (NPWT) for Szilagyi grade III (i.e. the arterial implant proper involved in the infection) peripheral vascular graft infection. Altogether, 69 papers were found using the reported search. From the search results, reference lists of potentially eligible studies and related citations in PubMed, seven papers represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. In the only randomized, controlled trial that compared NPWT (n = 10) and alginate dressing change (n = 10), the NPWT group demonstrated shorter time to full skin epithelialization (median 57 vs 104 days; P = 0.026). In the other six case series, the recruited case number ranged from 12 to 72. The mode of NPWT varied among the included studies, with the majority using a continuous negative pressure of 125 mmHg. One study combined NPWT and sartorius myoplasty, another used sartorius myoplasty in selected cases and others did not. The mean duration of using NPWT ranged from 14.2 to 43 days. The mean duration to achieve complete wound healing ranged from 24 (the study with sartorius myoplasty) to 51 days. The NPWT treatment failure rate ranged from 0 (the study with sartorius myoplasty) to 25%. The major complication of NPWT was bleeding and the incidence rate was reported to be <10%. We conclude that the amount of evidence for recommending NPWT alone as the first-line treatment for Szilagyi grade III peripheral vascular graft infection is small with only one small-sized randomized controlled trial demonstrating that NPWT alone is superior to alginate dressing change in shortening the time to complete wound healing by 2 months. Limited evidence (case series with >1 year of follow-up) showed that NPWT with a continuous negative pressure of 125 mmHg, or combined NPWT and sartorius myoplasty, may shorten the time to complete wound healing by 2 months, have a >70% success rate, and have a <10% NPWT-related complication rate.
C1 [Cheng, Hsu-Tang; Hsu, Yung-Chang; Wu, Chao-I] China Med Univ Hosp, Dept Surg, Taichung, Taiwan.
   [Cheng, Hsu-Tang; Hsu, Yung-Chang; Wu, Chao-I] China Med Univ, Sch Med, Taichung, Taiwan.
C3 China Medical University Taiwan; China Medical University Hospital -
   Taiwan; China Medical University Taiwan
RP Cheng, HT (通讯作者)，China Med Univ Hosp, Dept Surg, Taichung, Taiwan.
EM hsutangcheng@gmail.com
CR Berger P, 2012, J VASC SURG, V56, P714, DOI 10.1016/j.jvs.2012.02.007
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NR 8
TC 16
Z9 20
U1 0
U2 2
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
EI 1569-9285
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD DEC
PY 2014
VL 19
IS 6
BP 1048
EP U235
DI 10.1093/icvts/ivu289
PG 6
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA AY5OR
UT WOS:000347622300032
PM 25185571
OA Bronze
DA 2026-07-24
ER

PT J
AU Chen, SJ
   Ji, N
   Chen, YX
   Xiao, JR
   Wei, XZ
   Liu, YK
AF Chen, Shu-Jun
   Ji, Ning
   Chen, Yu-Xuan
   Xiao, Jian-Rui
   Wei, Xiao-Zong
   Liu, Yan-Kun
TI Effectiveness of negative pressure wound therapy in Ludwig's angina: a
   retrospective study of 18 cases
SO BMC SURGERY
LA English
DT Article
DE Negative pressure wound therapy; Ludwig's angina; Necrotizing soft
   tissue infection; Necrotizing fasciitis
ID CERVICAL NECROTIZING FASCIITIS; VACUUM-ASSISTED CLOSURE; MANAGEMENT;
   HEAD
AB Objective To investigate the effectiveness of negative pressure wound therapy (NPWT) for Ludwig's angina (LA). Methods We retrospectively reviewed 18 patients with LA admitted to the 82nd Group Army Hospital of PLA between October 2014 and October 2021. All patients underwent surgical drainage and debridement within 6 h after admission. A minimally invasive approach involving bilateral small incisions in the submandibular area was used to perform the procedure. An NPWT device was applied for positive drainage of the involved spaces after debridement. Postoperatively, the patients received the appropriate supportive care and antibiotic therapy. Data collection encompassed sex, age, systemic diseases, dressing change frequency, NPWT duration, wound healing time, and ICU stay length. Follow-up was performed to evaluate recurrence, scarring, and neck mobility. For comparative analysis, control data were obtained from LA patients treated with conventional surgical drainage between January 2008 and September 2014. Descriptive statistics and Student's t-test were employed for statistical analysis. Results In the NPWT group, all patients had uneventful courses during hospitalization and were discharged upon complete wound healing. Fifteen patients required only a single session of surgical debridement with NPWT, while the remaining three underwent two procedures. Upon NPWT device removal, all infectious cavities exhibited clean wounds with mature granulation tissue formation. Compared to the conventional surgery group, the NPWT group demonstrated a significantly shorter wound healing time (15.33 +/- 3.93 vs. 19.50 +/- 2.17 days; p = 0.025), reduced ICU stay duration (0.61 +/- 0.61 vs. 2.17 +/- 0.75 days; p < 0.001) and markedly fewer dressing changes (2.17 +/- 0.38 vs. 17.00 +/- 3.16; p < 0.001). Conclusions NPWT demonstrated excellent effectiveness in the management of LA. Compared to conventional surgical debridement and drainage, it offers several distinct clinical advantages, including accelerated wound healing, shortened ICU stays, and reduced dressing change frequency. These benefits are clinically linked to both reduced postoperative pain perception and decreased nursing workload. Additionally, smaller incisions result in less surgical trauma and improved cosmetic outcomes. NPWT should be considered as a viable approach in the management of LA. Future randomized controlled trials are needed to confirm NPWT's superiority in larger cohorts.
C1 [Chen, Shu-Jun; Chen, Yu-Xuan; Xiao, Jian-Rui; Wei, Xiao-Zong; Liu, Yan-Kun] 82nd Grp Army Hosp PLA, Dept Stomatol, 991 Baihuadong Rd, Baoding 071000, Peoples R China.
   [Ji, Ning] 82nd Grp Army Hosp PLA, Qual Management Dept, 991 Baihuadong Rd, Baoding 071000, Peoples R China.
RP Chen, SJ (通讯作者)，82nd Grp Army Hosp PLA, Dept Stomatol, 991 Baihuadong Rd, Baoding 071000, Peoples R China.
EM shujunchen001@163.com
RI Ji, Ning/PJS-8848-2026; Liu, Yankun/ORJ-7187-2025
FU Medical Science Foundation of the PLA Central Theater Command Army [:,
   2023LC05]
FX This work is supported by the Medical Science Foundation of the PLA
   Central Theater Command Army (grant:No. 2023LC05).
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
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NR 25
TC 0
Z9 0
U1 0
U2 1
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2482
J9 BMC SURG
JI BMC Surg.
PD MAY 22
PY 2025
VL 25
IS 1
AR 223
DI 10.1186/s12893-025-02957-y
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 2WB8A
UT WOS:001492697500002
PM 40399898
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU De Pellegrin, L
   Feltri, P
   Filardo, G
   Candrian, C
   Harder, Y
   Galetti, K
   De Monti, M
AF De Pellegrin, Laura
   Feltri, Pietro
   Filardo, Giuseppe
   Candrian, Christian
   Harder, Yves
   Galetti, Ken
   De Monti, Marco
TI Effects of negative pressure wound therapy with instillation and dwell
   time (NPWTi-d) versus NPWT or standard of care in orthoplastic surgery:
   A systematic review and meta-analysis
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Review
DE negative pressure wound therapy; NPWT; NPWTi-d; acute wound; chronic
   wound; infection; orthoplastic surgery
ID VACUUM-ASSISTED CLOSURE; ANTISEPTIC SOLUTION; SALINE; MANAGEMENT; TRIAL;
   FOAM
AB Negative pressure wound therapy (NPWT) is a wound-dressing system that applies sub-atmospheric pressure on the surface of a wound to promote healing. An evolution of this technology, NPWT with solution instillation and dwell time (NPWTi-d), is increasingly being used to maximise wound closure and reduce failure rates. However, there is still a lack of evidence concerning its use in orthoplastic surgery. Therefore, the aim of this study is to compare NPWTi-d with NPWT and standard of care for wound management in orthoplastic surgery. A comprehensive literature search using PubMed, Web of Science, and Cochrane databases up to 15 March 2022 was performed, including studies describing the outcomes of NPWTi-d for traumatic/orthopaedic injuries. A meta-analysis on the number of surgical debridements, as well as the rate of complete wound closure and complications was carried out, although for other outcomes, a descriptive statistic was applied. Risk of bias and quality of evidence were assessed using the Downs& Black's Checklist for Measuring Quality. Thirteen studies with a total number of 871 patients were included, in which NPWTi-d demonstrated significantly higher primary wound closure and lower complication rates (P < .05). No difference in the number of surgical procedures required for final wound healing was observed. Moreover, five out of six studies showed better results for NPWTi-d when the change of the bioburden and bacterial count of the wound were analysed. A singular study investigating the length of the hospital stay of patients treated with NPWTi-d showed a reduction in the latter. The present meta-analysis proves that NPWTi-d is superior to NPTW or conventional dressings in orthoplastic wound care management, in terms of complete wound closure rate and the reduced number of complications. Still, the limited quality of the studies analysed shows that future randomised studies are needed to confirm the benefits and to identify the most appropriate recommendations for using NPWTi-d in orthoplastic surgery, as well as to investigate the cost-effectiveness of this wound-dressing system.
C1 [De Pellegrin, Laura; Galetti, Ken; De Monti, Marco] Ente Osped Cantonale EOC, Osped Reg Mendrisio, Dept Gen Surg, Mendrisio, Switzerland.
   [Feltri, Pietro; Filardo, Giuseppe; Candrian, Christian] Ente Osped Cantonale EOC, Serv Orthopaed & Traumatol, Dept Surg, Lugano, Switzerland.
   [Filardo, Giuseppe; Candrian, Christian; Harder, Yves] Univ Svizzera Italiana, Fac Biomed Sci, Lugano, Switzerland.
   [Harder, Yves; De Monti, Marco] Ente Osped Cantonale EOC, Osped Reg Lugano, Dept Plast Reconstruct & Aesthet Surg, Mendrisio, Switzerland.
   [De Monti, Marco] Ente Osped Cantonale EOC, Osped Reg Mendrisio, Dept Gen Surg, Via Turconi 23, CH-6850 Mendrisio, Switzerland.
C3 Universita della Svizzera Italiana
RP De Monti, M (通讯作者)，Ente Osped Cantonale EOC, Osped Reg Mendrisio, Dept Gen Surg, Via Turconi 23, CH-6850 Mendrisio, Switzerland.
EM marco.demonti@eoc.ch
RI De Monti, Marco/HJI-5543-2023
OI De Monti, Marco/0000-0003-0927-3438
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NR 36
TC 28
Z9 31
U1 1
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD AUG
PY 2023
VL 20
IS 6
BP 2402
EP 2413
DI 10.1111/iwj.14072
EA JAN 2023
PG 12
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA L4AN9
UT WOS:000906029100001
PM 36594491
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Struyve, M
   De Vloo, C
   Van Veer, H
   Depypere, L
   Nafteux, P
   Roelandt, P
AF Struyve, M.
   De Vloo, C.
   Van Veer, H.
   Depypere, L.
   Nafteux, P.
   Roelandt, P.
TI Endoscopic vacuum-assisted closure therapy for the treatment of
   oesophageal anastomotic leaks
SO ACTA GASTRO-ENTEROLOGICA BELGICA
LA English
DT Article
DE oesophagus; anastomotic leak; perforation; endoluminal vacuum therapy;
   endoscopic vacuum-assisted closure therapy
ID PERFORATIONS
AB Persisting suture dehiscence with oesophageal anastomotic leaks after thoracic surgery is a difficult complication, especially when a surgical repair fails. We report here endoscopic vacuum-assisted closure therapy as a novel endoscopic treatment for the management of oesophageal anastomotic leaks. Endoscopic vacuum-assisted closure therapy is a minimally invasive method to treat anastomotic leakage by positioning an open-pored polyurethane sponge and a suction tube connected to a wound drainage system into the opening of the wound cavity. This multidisciplinary endoscopic and surgical approach is a successful therapy for the management of suture dehiscence with oesophageal anastomotic leaks after thoracic surgery or oesophageal perforations.
C1 [Struyve, M.; De Vloo, C.; Roelandt, P.] Katholieke Univ Leuven, Univ Hosp Leuven, Dept Gastroenterol & Hepatol, Herestr 49, B-3000 Leuven, Belgium.
   [Struyve, M.] ZOL, Dept Gastroenterol & Hepatol, Genk, Belgium.
   [Van Veer, H.; Depypere, L.; Nafteux, P.] Katholieke Univ Leuven, Univ Hosp Leuven, Dept Thorac Surg, Leuven, Belgium.
C3 KU Leuven; University Hospital Leuven; East Limburg Hospital; KU Leuven;
   University Hospital Leuven
RP Struyve, M (通讯作者)，Katholieke Univ Leuven, Univ Hosp Leuven, Dept Gastroenterol & Hepatol, Herestr 49, B-3000 Leuven, Belgium.
EM mathieustruyve@me.com
RI ; Van Veer, Hans/K-6754-2019
OI Depypere, Lieven/0000-0001-8230-5649; Van Veer,
   Hans/0000-0003-1153-8298; Struyve, Mathieu/0000-0002-6933-3810
CR Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Rogalski P, 2015, WORLD J GASTROENTERO, V21, P10542, DOI 10.3748/wjg.v21.i37.10542
   Schniewind B, 2013, SURG ENDOSC, V27, P3883, DOI 10.1007/s00464-013-2998-0
   Siersema PD, 2005, GASTROINTEST ENDOSC, V61, P897, DOI 10.1016/S0016-5107(05)01589-0
NR 4
TC 2
Z9 4
U1 0
U2 0
PU UNIV CATHOLIQUE LOUVAIN-UCL
PI BRUSSELS
PA CLIN UNIV SAINT LUC, AVE HIPPOCRATE 10, BRUSSELS, B-1200, BELGIUM
SN 1784-3227
J9 ACTA GASTRO-ENT BELG
JI Acta Gastro-Enterol. Belg.
PD OCT-DEC
PY 2019
VL 82
IS 4
BP 529
EP 531
PG 3
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA KF6SS
UT WOS:000509370700009
PM 31950809
DA 2026-07-24
ER

PT J
AU Sziklavari, Z
   Ried, M
   Neu, R
   Schemm, R
   Grosser, C
   Szöke, T
   Hofmann, HS
AF Sziklavari, Zsolt
   Ried, Michael
   Neu, Reiner
   Schemm, Rudolf
   Grosser, Christian
   Szoeke, Tamas
   Hofmann, Hans-Stefan
TI Mini-open vacuum-assisted closure therapy with instillation for
   debilitated and septic patients with pleural empyema
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article
DE Vacuum-assisted closure; Negative pressure wound therapy; Instillation;
   Empyema; Minimally invasive
ID OPEN-WINDOW THORACOSTOMY; THORACIC EMPYEMA; POSTPNEUMONECTOMY EMPYEMA;
   INTRATHORACIC APPLICATION; LUNG RESECTION; MANAGEMENT; PERSISTENT;
   SURGERY; DEVICE; OPTION
AB OBJECTIVES: This prospective study is an evaluation of the mini-open vacuum-assisted closure with instillation (Mini-VAC-Instill) therapy for the treatment of complicated pleural empyema.
   METHODS: We investigated septic patients in poor general physical condition (Karnofsky index <= 50%) with multimorbidity and/or immunosuppression who were treated by minimally invasive intrathoracic VAC-Instill therapy without the insertion of an open-window thoracostomy (OWT) between December 2012 and November 2014. All patients underwent mini-thoracotomy with position of a tissue retractor, surgical debridement and local decortication. Surgery was followed by intrathoracic vacuum therapy including periodic instillation using antiseptics. The VAC dressings were changed under general anaesthesia and the chest wall was closed during the same hospital stay. All patients received systemic antibiotic therapy.
   RESULTS: Fifteen patients (13 males, median age: 71 years) underwent intrathoracic Mini-VAC-Instill dressings for the management of pleural empyema without bronchopleural fistula. The median length of vacuum therapy was 9 days (5-25 days) and the median number of VAC changes per patient was 1 (1-5). In-hospital mortality was 6.7% (n = 1) and was not related to Mini-VAC-Instill therapy or intrathoracic infection. Control of intrathoracic infection and closure of the chest cavity was achieved in 85.7% of surviving patients (12 of 14). After the follow-up at an average of 13.2 months (range, 3-25 months), we observed recurrence once, 21 days after discharge. Two patients died in the late postoperative period (Day 43 and Day 100 after discharge) of fulminant urosepsis and carcinoma-related multiorgan failure, respectively. Analysis of the follow-up interviews in the outpatient clinic showed a good quality of life and a subjectively good long-term aesthetic result.
   CONCLUSIONS: Mini-VAC-Instill therapy is an upgrade of Mini-VAC, which guarantees the advantage of an open treatment, including flushing but without OWT. This procedure is minimally invasive, highly compatible especially with patients in poor general condition and may be an alternative to the OWT in selected patients. Consequently, a very short course of therapy results in good patient acceptance.
C1 [Sziklavari, Zsolt; Schemm, Rudolf; Grosser, Christian; Szoeke, Tamas; Hofmann, Hans-Stefan] Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, D-93049 Regensburg, Germany.
   [Ried, Michael; Neu, Reiner; Hofmann, Hans-Stefan] Univ Regensburg, Dept Thorac Surg, D-93053 Regensburg, Germany.
C3 University of Regensburg
RP Sziklavari, Z (通讯作者)，Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, Prufeningerstr 86, D-93049 Regensburg, Germany.
EM zsolt.sziklavari@barmherzige-regensburg.de
RI Ried, Michael/AAC-4518-2022; Sziklavari, Zsolt/AGI-2440-2022
OI Ried, Michael/0000-0002-2365-4803; 
CR Al-Mufarrej F, 2010, SURG TODAY, V40, P711, DOI 10.1007/s00595-008-4096-9
   Allen D, 2014, INT WOUND J, V11, P198, DOI 10.1111/j.1742-481X.2012.01073.x
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   Wolvos Tom, 2004, Ostomy Wound Manage, V50, P56
NR 25
TC 18
Z9 28
U1 0
U2 7
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
EI 1873-734X
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD AUG
PY 2015
VL 48
IS 2
BP E9
EP E16
DI 10.1093/ejcts/ezv186
PG 8
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA CO7CM
UT WOS:000359315100001
PM 26017017
OA Bronze
DA 2026-07-24
ER

PT J
AU Wright, H
   Kearney, S
   Zhou, K
   Woo, K
AF Wright, Heather
   Kearney, Stephanie
   Zhou, Kevin
   Woo, Kevin
TI Topical Management of Enterocutaneous and Enteroatmospheric Fistulas: A
   Systematic Review
SO WOUND MANAGEMENT & PREVENTION
LA English
DT Review
DE systematic review; enterocutaneous fistula; enteroatmospheric fistula;
   management; negative pressure wound therapy
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; SMALL-BOWEL FISTULAS;
   ABDOMINAL WOUNDS; OPEN ABDOMEN; EXPERIENCE; RECURRENCE; NUTRITION;
   MORTALITY; REPAIR
AB Enterocutaneous (ECF) and enteroatmospheric (EAF) fistulas are associated with considerable morbidity and patient care challenges, including optimal topical management. PURPOSE: A systematic literature review was conducted to identify topical management interventions used in ECF/EAF care and to explore the role of these interventions in fistula closure and long-term fistula management. METHODS: A search of PubMed, the Cumulative Index of Nursing and Allied Health Literature, and Scopus was conducted to identify English-language articles published from January 2004 to January 2019. The keywords enterocutaneous fistula, enteroatmospheric fistula, negative pressure wound therapy, NPWT, vacuum-assisted closure, VAC, pouch or pouching, troughing, bridging, collection device, dressing, and wound care were used to identify all publications pertaining to the topical management of adult and mixed adult/pediatric patients with an ECF or EAF. Single-person case studies, exclusively pediatric studies, surgical treatment-based, and duplicate publications were excluded. Abstracts were screened for relevance to the research questions, and eligible publications were abstracted and categorized using The Oxford Centre for Evidence-Based Medicine Levels of Evidence. The Joanna Briggs Institute (JBI) critical appraisal checklist for case series was used to assess each article for risk of bias and methodological quality. Outcomes of interest included patient demographics, closure rates, fistula classification (type of fistula, fistula output, fistula origin), type of topical treatment, adverse events (pain, new fistula formation, fistula recurrence, mortality), follow-up, long-term management, perifistula skin protection, effluent management, dressing change frequency, and quality of life. Descriptive statistics were presented; no statistical analysis was performed. RESULTS: Of the 983 articles identified, 57 underwent critical appraisal using the JBI checklist for case series. Forty-two (42) did not meet the inclusion criteria, leaving 15, level IV, case-based publications (N = 410 patients). No randomized controlled trials were found. All studies included some form of negative pressure wound therapy. JBI results found that each study was at high risk of bias in more than 2 domains. Interventions were categorized as intubation, occlusion, or isolation of the fistula. Of the 559 fistulas treated, spontaneous closure was reported in 164 cases, with rates ranging from 0% to 100%. Adverse events to treatment included pain (n = 33 patients), new fistula formation (n = 12), and fistula recurrence (n = 1). Sepsis was the leading cause of mortality (n = 29), with reported rates ranging from 0% to 44%. CONCLUSION: Due to the high risk of study bias and low quality of evidence, the exact contribution of any one intervention could not be established. Results also suggest a high risk of publication bias, and patient-centered outcomes were reported in only 1 study. Although topical management might play a role in fistula closure, it is only as part of a comprehensive plan of care. Future research should focus on developing and using standardized reporting tools, classifications, and outcomes and include patient-centered outcomes such as acceptance, tolerability, pain, and quality of life relating to any one intervention. At this time, the evidence base for management recommendations is limited, suggesting that interventions should mainly be based on practical considerations such as resources and clinician skill.
C1 [Wright, Heather] Keewaytinook Okimakanak First Nat Tribal Council, Wound Ost & Continence Care, Leamington, ON, Canada.
   [Kearney, Stephanie] Queensway Carleton Hosp, Wound Ost & Continence Care, Ottawa, ON, Canada.
   [Zhou, Kevin] Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada.
   [Woo, Kevin] Queens Univ, Kingston, ON, Canada.
C3 University of Toronto; Sunnybrook Health Science Center; Sunnybrook
   Research Institute; Queens University - Canada
RP Wright, H (通讯作者)，Keewaytinook Okimakanak Hlth, 69 Alderton St, Leamington, ON, Canada.
EM wright.he@gmail.com
CR [Anonymous], 2013, NEG PRESS WOUND THER
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NR 42
TC 10
Z9 17
U1 0
U2 20
PU HMP
PI MALVERN
PA 70 E SWEDESFORD RD, STE 100, MALVERN, PA 19355 USA
SN 2640-5237
EI 2640-5245
J9 WOUND MANAG PREV
JI Wound Manag. Prev.
PD APR
PY 2020
VL 66
IS 4
BP 26
EP 37
DI 10.25270/wmp.2020.4.2637
PG 12
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA OR3CX
UT WOS:000589352700002
PM 32294057
DA 2026-07-24
ER

PT J
AU Wu, YZ
   Huang, CH
   Zhang, XY
   Shen, GL
AF Wu, Yi-Zhu
   Huang, Chun-Hui
   Zhang, Xin-Yu
   Shen, Guo-Liang
TI The clinical application effects of artificial dermis scaffold and
   autologous split-thickness skin composite grafts combined with
   vacuum-assisted closure in refractory wounds
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE artificial dermis scaffold; autologous split-thickness skin graft;
   refractory wounds; vacuum-assisted closure; wound healing
ID THERAPY
AB To investigate the clinical application effects of artificial dermis scaffold and autologous split-thickness skin composite grafts combined with vacuum-assisted closure (V.A.C) in refractory wounds. A retrospective analysis was performed on 70 patients with refractory wounds admitted to the First Affiliated Hospital of Soochow University from June 2019 to December 2021 (44 males and 25 females, with an average age of 49.3 +/- 21.4 years). There were 26 patients with chronic ulcers; 3 patients with cancerous wounds; 16 patients with hot crush injuries; and 25 patients with traumatic wounds, including 21 cases of hands, 33 cases of feet, 6 cases of upper limbs, and 10 cases of lower limbs. The patients were divided into an artificial dermis scaffold group (35 patients, including 21 males and 14 females, aged 49.5 +/- 21.3 years) and a skin graft group (35 patients, including 23 males and 11 females, aged 49.1 +/- 21.5 years). In the artificial dermis scaffold group, after debridement, the artificial dermis scaffold was transplanted for approximately 2 weeks until the wound surface was well vascularized, after which the autologous split-thick skin graft was transplanted. Negative pressure wound therapy was performed throughout the treatment. In the skin grafting group, after debridement, the autologous split-thickness skin graft (aSTSG) was transplanted, and negative pressure wound therapy was performed continuously. The wound healing rate; skin graft survival rate; postoperative wound infection; exudative fluid volume; subcutaneous haematoma; hospitalisation time; hospitalisation cost; Vancouver Scar Scale (VSS) score, used to evaluate the scar of the recipient area at 6 months after the operation; and the sensory disorder grading method, used to evaluate the sensory recovery of the recipient area, were compared between the two groups. All 70 refractory wounds healed. In the artificial dermis scaffold group, the skin graft survival rate was 90% (86%-95%), the hospitalisation time was 38 (29-45) days, the hospitalisation cost was 148 102 (118242-192327) yuan, and the VSS score was 1.9 +/- 1.3. There were significant differences in skin graft survival rate (70% [60%-80%]), length of hospital stay (21 [14-28] days), hospitalisation cost (76 201 [39228-135 919] yuan) and VSS score [6.1 +/- 3.6] between the skin graft group and the artificial dermis scaffold group (P < .05). The skin graft survival rate, scar hyperplasia and sensory recovery of the recipient area in the artificial dermis scaffold group were better than those in the skin graft group, but the hospitalisation time was relatively longer, and the hospitalisation cost was relatively higher. Wound healing rate, postoperative wound infection, exudate volume, and subcutaneous haematoma of patients in the two groups were similar, and there were no significant differences (P > .05). The artificial dermis scaffold and composite transplantation of autologous aSTSG with V.A.C can promote painless wound healing and improve the skin survival rate, skin colour and lustre, and flexible smooth texture and is conducive to less scar hyperplasia and postoperative functional exercise and recovery. This method provides a reasonable and effective scheme for the treatment of clinical refractory wounds.
C1 [Wu, Yi-Zhu; Huang, Chun-Hui; Zhang, Xin-Yu; Shen, Guo-Liang] Soochow Univ, Affiliated Hosp 1, Dept Burn & Plast Surg, Suzhou, Peoples R China.
   [Shen, Guo-Liang] Soochow Univ, Affiliated Hosp 1, Dept Burn & Plast Surg, 188 Shizi St, Suzhou 215000, Peoples R China.
C3 Soochow University - China; Soochow University - China
RP Shen, GL (通讯作者)，Soochow Univ, Affiliated Hosp 1, Dept Burn & Plast Surg, 188 Shizi St, Suzhou 215000, Peoples R China.
EM sdfyysgl@163.com
RI ; huang, chunhui/HJA-1599-2022
OI Wu, Yizhu/0000-0002-4066-1204; 
FU National Natural Science Foundation of China [31370968]
FX National Natural Science Foundation of China, Grant/Award Number:
   31370968
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NR 15
TC 15
Z9 18
U1 0
U2 25
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD AUG
PY 2023
VL 20
IS 6
BP 2113
EP 2120
DI 10.1111/iwj.14086
EA FEB 2023
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA L4AN9
UT WOS:000924050700001
PM 36726042
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kalender, AM
   Baykan, H
   Özkan, F
   Çiralik, H
   Öztürk, P
   Gül, M
   Uçmak, H
AF Kalender, Ali Murat
   Baykan, Halit
   Ozkan, Fuat
   Ciralik, Harun
   Ozturk, Perihan
   Gul, Mustafa
   Ucmak, Hasan
TI Negative Pressure Wound Therapy and Skin Graft in Madura Foot Treatment
SO BALKAN MEDICAL JOURNAL
LA English
DT Editorial Material
DE Madura foot; negative pressure wound therapy; split thickness skin graft
ID MYCETOMA; INFECTION
AB Madura foot is a rare, loca, chronic granulomatous skin infection which commonly affects the adult male foot. Medical treatment reduces the size of the lesion but surgical excision is necessary for radical treatment. We present a case of a 59 year old male farmer diagnosed as actinomadura of the right foot treated with medical treatment, total excision, negative pressure wound therapy and split thickness skin graft.
C1 [Kalender, Ali Murat] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Orthopaed & Traumatol, TR-46050 Kahramanmaras, Turkey.
   [Baykan, Halit] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-46050 Kahramanmaras, Turkey.
   [Ozkan, Fuat] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Radiol, TR-46050 Kahramanmaras, Turkey.
   [Ciralik, Harun] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Pathol, TR-46050 Kahramanmaras, Turkey.
   [Ozturk, Perihan] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Dermatol, TR-46050 Kahramanmaras, Turkey.
   [Gul, Mustafa] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Microbiol, TR-46050 Kahramanmaras, Turkey.
   [Ucmak, Hasan] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Infect Dis, TR-46050 Kahramanmaras, Turkey.
C3 Kahramanmaras Sutcu Imam University; Kahramanmaras Sutcu Imam
   University; Kahramanmaras Sutcu Imam University; Kahramanmaras Sutcu
   Imam University; Kahramanmaras Sutcu Imam University; Kahramanmaras
   Sutcu Imam University; Kahramanmaras Sutcu Imam University
RP Kalender, AM (通讯作者)，Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Orthopaed & Traumatol, TR-46050 Kahramanmaras, Turkey.
EM kalenderalimurat@hotmail.com
RI GUL, MUSTAFA/MBV-0106-2025
CR Ahmed A, 2003, J CLIN MICROBIOL, V41, P4537, DOI 10.1128/JCM.41.10.4537-4541.2003
   Ahmed A, 2002, J CLIN MICROBIOL, V40, P1031, DOI 10.1128/JCM.40.3.1031-1036.2002
   Ahmed AOA, 2004, LANCET INFECT DIS, V4, P566, DOI 10.1016/S1473-3099(04)01131-4
   BURKUS JK, 1985, FOOT ANKLE, V6, P47, DOI 10.1177/107110078500600110
   Cipolla J., 2008, OPUS, V12, P15
   FAHAL AH, 1994, T ROY SOC TROP MED H, V88, P78, DOI 10.1016/0035-9203(94)90509-6
   Fahal AH, 2004, T ROY SOC TROP MED H, V98, P3, DOI 10.1016/S0035-9203(03)00009-9
   FAHAL AH, 1992, BJS-BRIT J SURG, V79, P1138, DOI 10.1002/bjs.1800791107
   GUMAA SA, 1986, AM J TROP MED HYG, V35, P594, DOI 10.4269/ajtmh.1986.35.594
   Hag IAEL, 1996, ACTA CYTOL, V40, P461, DOI 10.1159/000333899
   Jones JE, 2007, COCHRANE DB SYST REV, V18
   Mahgoub ES, 1994, SUDAN MED J, V32, P88
   MCELROY JA, 1992, CUTIS, V49, P107
   Sarris I, 2003, SKELETAL RADIOL, V32, P179, DOI 10.1007/s00256-002-0600-2
   Van der Velde M, 2005, ANN PLAS SURG, V55, P660, DOI 10.1097/01.sap.0000187181.59748.19
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Young BA, 2000, J AM PODIAT MED ASSN, V90, P81, DOI 10.7547/87507315-90-2-81
NR 17
TC 4
Z9 4
U1 0
U2 3
PU GALENOS PUBL HOUSE
PI ISTANBUL
PA MOLLA GURANI MAHALLESI KACAMAK SOKAK NO 21-1, ISTANBUL, TURKEY
SN 2146-3123
EI 2146-3131
J9 BALK MED J
JI Balk. Med. J.
PY 2012
VL 29
IS 2
BP 214
EP 217
DI 10.5152/balkanmedj.2012.014
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 097WR
UT WOS:000315504700023
PM 25207000
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ramanujam, CL
   Zgonis, T
AF Ramanujam, Crystal L.
   Zgonis, Thomas
TI Surgical Soft Tissue Closure of Severe Diabetic Foot Infections: A
   Combination of Biologics, Negative Pressure Wound Therapy, and Skin
   Grafting
SO CLINICS IN PODIATRIC MEDICINE AND SURGERY
LA English
DT Article
DE Diabetic foot; Wounds; Neuropathy; Biologics; Negative pressure wound
   therapy; Amputation
AB Creative surgical strategies are often warranted for long-term closure of diabetic foot wounds. This article provides a case report describing the successive use of negative pressure wound therapy, advanced biologics, and split thickness skin grafting for healing an extensive surgical wound. Although the success of these therapies is enticing, their use should be based on careful patient selection in a multidisciplinary setting.
C1 [Ramanujam, Crystal L.; Zgonis, Thomas] Univ Texas Hlth Sci Ctr San Antonio, Dept Orthopaed Surg, Div Podiatr Med & Surg, San Antonio, TX 78229 USA.
C3 University of Texas System; University of Texas at San Antonio
RP Zgonis, T (通讯作者)，Univ Texas Hlth Sci Ctr San Antonio, Dept Orthopaed Surg, Div Podiatr Med & Surg, 7703 Floyd Curl Dr MSC 7776, San Antonio, TX 78229 USA.
EM zgonis@uthscsa.edu
CR Capobianco Claire M, 2010, Foot Ankle Spec, V3, P241, DOI 10.1177/1938640010375113
   Clemens Mark W, 2010, Surg Technol Int, V20, P61
   Collier Mark, 2006, Nurs Stand, V21, ppassim
   Ramanujam CL, 2010, J WOUND CARE, V19, P56, DOI 10.12968/jowc.2010.19.2.46967
   Ramsey SD, 1999, DIABETES CARE, V22, P382, DOI 10.2337/diacare.22.3.382
   Reiber GE, 1998, AM J SURG, V176, p5S, DOI 10.1016/S0002-9610(98)00181-0
   Roukis TS, 2009, SURG RECONSTRUCTION, P129
NR 7
TC 8
Z9 11
U1 0
U2 9
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0891-8422
EI 1558-2302
J9 CLIN PODIATR MED SUR
JI Clin. Podiatr. Med. Surg.
PD JAN
PY 2012
VL 29
IS 1
BP 143
EP +
DI 10.1016/j.cpm.2011.10.004
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 044VB
UT WOS:000311651100014
PM 22243576
DA 2026-07-24
ER

PT J
AU Wang, WH
   Chang, YW
   Liu, SY
AF Wang, Wenhui
   Chang, Yaowen
   Liu, Shengye
TI A commentary on "A systematic review and meta-analysis comparing the
   effectiveness of negative-pressure wound therapy to standard therapy in
   the prevention of complications after vascular surgery" (Int J Surg
   2020; 76: 94-150)
SO INTERNATIONAL JOURNAL OF SURGERY
LA English
DT Editorial Material
DE Negative-pressure wound therapy; Standard therapy; Vascular surgery;
   Complications
C1 [Wang, Wenhui; Chang, Yaowen; Liu, Shengye] Lanzhou Univ, Hosp 1, Dept Intervent Med, Lanzhou 730000, Gansu, Peoples R China.
C3 Lanzhou University
RP Wang, WH (通讯作者)，Lanzhou Univ, Hosp 1, Dept Intervent Med, Lanzhou 730000, Gansu, Peoples R China.
EM wangwenhui1968@126.com
CR Humphreys H, 2009, J HOSP INFECT, V73, P316, DOI 10.1016/j.jhin.2009.03.028
   Koetje J.H., 2015, SURG RES PRACT
   Sexton F, 2020, INT J SURG, V76, P94, DOI 10.1016/j.ijsu.2020.02.037
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
NR 4
TC 0
Z9 0
U1 0
U2 5
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 1743-9191
EI 1743-9159
J9 INT J SURG
JI Int. J. Surg.
PD JUL
PY 2021
VL 91
AR 105998
DI 10.1016/j.ijsu.2021.105998
EA JUL 2021
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA TH1CW
UT WOS:000671833100017
PM 34133984
DA 2026-07-24
ER

PT J
AU Nherera, LM
   Trueman, P
   Karlakki, SL
AF Nherera, Leo M.
   Trueman, Paul
   Karlakki, Sudheer L.
TI Cost-effectiveness analysis of single-use negative pressure wound
   therapy dressings (sNPWT) to reduce surgical site complications (SSC) in
   routine primary hip and knee replacements
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID TRIAL
AB We sought to evaluate the cost-effectiveness of single-use negative pressure wound therapy in patients undergoing primary hip and knee replacements using effectiveness data from a recently completed non-blinded randomized controlled trial. A decision analytic model was developed from UK National Health Service perspective using data from a single-centre trial. 220 patients were randomized to treatment with either single-use negative pressure wound therapy or standard care i.e., film dressings of clinician choice and followed for 6 weeks. Outcomes included dressing changes, length of stay, surgical site complications, cost and quality adjusted life years. The randomized controlled trial reported a reduction in dressing changes (p = 0.002), SSC (p = 0.06) and LOS (p = 0.07) in favor of single-use negative pressure wound therapy compared with standard care. The model estimated 0.116 and 0.115 QALY gained, 0.98 and 0.92 complications avoided for single-use negative pressure wound therapy and standard care, respectively. The cost/patient was 5,602 pound ($7,954) and 6,713 pound ($9,559) for single-use negative pressure wound therapy and standard care respectively resulting in cost-saving of 1,132 pound ($1,607) in favor of single-use negative pressure wound therapy. Greater savings were observed in subgroups of higher risk patients with BMI >= 35 and ASA >= 3 i.e., 7,955 pound ($11,296) and 7,248 pound ($10,293), respectively. The findings were robust to a range of sensitivity analyses. In conclusion, single-use negative pressure wound therapy can be considered a cost saving intervention to reduce surgical site complications following primary hip and knee replacements compared with standard care. Providers should consider targeting therapy to those patients at elevated risk of surgical site complications to maximize efficiency.
C1 [Nherera, Leo M.; Trueman, Paul] Smith & Nephew Adv Wound Management, Kingston Upon Hull HU3 2BN, N Humberside, England.
   [Karlakki, Sudheer L.] Robert Jones & Agnes Hunt Orthopaed NHS Hosp Fdn, Oswestry SY10 7AG, Shrops, England.
C3 Smith & Nephew
RP Nherera, LM (通讯作者)，Smith & Nephew, Global Market Access, 101 Hessle Rd, Kingston Upon Hull HU3 2BN, N Humberside, England.
EM leo.nherera@smith-nephew.com
RI Nherera, Leo/L-1978-2019
OI Nherera, Leo/0000-0003-1758-9504
CR [Anonymous], 2016, NHS ELECT DRUG TARIF
   [Anonymous], 2015, Personal Social Services Research Unit
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   Department of Health, NHS REF COSTS 2014 2
   Fenwick E, 2005, BRIT J PSYCHIAT, V187, P106, DOI 10.1192/bjp.187.2.106
   Health Protection Agency, 2011, PROT SURV SURG SIT I
   Hospital Episode Statistics, 2011, PROV MONTHL PAT REP
   Husereau D, 2013, VALUE HEALTH, V16, P231, DOI 10.1016/j.jval.2013.02.002
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Jenks PJ, 2014, J HOSP INFECT, V86, P24, DOI 10.1016/j.jhin.2013.09.012
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   National Institute for Health and Clinical Excellence, 2008, PREV TREATM SURG SIT
   Pellino G, 2014, SURG INNOV, V21, P204, DOI 10.1177/1553350613496906
   PHE, 2015, SURV SURG SIT INF NH
   Poultsides LA, 2013, J ARTHROPLASTY, V28, P385, DOI 10.1016/j.arth.2012.06.027
   Shmueli A, 1999, MED DECIS MAKING, V19, P122, DOI 10.1177/0272989X9901900202
   Smyth ETM, 2008, J HOSP INFECT, V69, P230, DOI 10.1016/j.jhin.2008.04.020
   Tanner J, 2009, J HOSP INFECT, V72, P243, DOI 10.1016/j.jhin.2009.03.021
   Vig S, 2011, J TISSUE VIABILITY, V20, pS1, DOI 10.1016/j.jtv.2011.07.002
   Welte R, 2004, PHARMACOECONOMICS, V22, P857, DOI 10.2165/00019053-200422130-00004
NR 21
TC 54
Z9 58
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAY-JUN
PY 2017
VL 25
IS 3
BP 474
EP 482
DI 10.1111/wrr.12530
PG 9
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA FF3BT
UT WOS:000408771200013
PM 28370637
OA Bronze
DA 2026-07-24
ER

PT J
AU Singh, H
   Avudaiappan, M
   Kharel, J
   Irrinki, S
   Kumar, H
   Savlania, A
   Sharma, V
   Gupta, V
   Yadav, TD
   Gupta, R
AF Singh, Harjeet
   Avudaiappan, Mohanasundaram
   Kharel, Jyoti
   Irrinki, Santosh
   Kumar, Hemant
   Savlania, Ajay
   Sharma, Vishal
   Gupta, Vikas
   Yadav, Thakur Deen
   Gupta, Rajesh
TI Negative pressure wound therapy versus standard care for incisional
   laparotomy subcutaneous wounds in gastrointestinal perforations: A
   randomized controlled study
SO SURGERY
LA English
DT Article
ID SURGICAL SITE INFECTION; DELAYED PRIMARY CLOSURE; TRIAL; PREVENTION
AB Background: Surgical site infections after gastrointestinal perforation with peritonitis have significant morbidity, increased hospital stays, and cost of treatment. The appropriate management of these wounds is still debatable.Methods: Patients undergoing surgery for gastrointestinal perforation with peritonitis via midline inci-sion were screened for inclusion. After the closure of the midline fascia, patients were randomized into an open negative pressure wound therapy group (application of negative pressure wound therapy and attempted delayed closure at day 4) or a standard care group (no negative pressure wound therapy and attempted delayed closure at day 4). Postoperative outcomes, including surgical site infection till 30 days, were compared between the groups. This was assessed by an independent assessor not involved in the study for delayed closure. Although a priori sample size was calculated, an interim analysis was per-formed due to slow recruitment during the COVID pandemic. After interim analysis, a continuation of the trial was deemed unethical and terminated.Results: Ninety-six patients were assessed, and 69 were randomized (34 in the negative pressure wound therapy group and 31 in the standard care group). The age, body mass index, comorbidities, blood loss, operative time, and stoma formation were comparable. The surgical site infection was significantly lower in the negative pressure wound therapy group compared to the standard care group (6 [18%] vs 19 [61%], P < .01). The number needed to prevent 1 surgical site infection was 2.3. In a subgroup analysis, the use of negative pressure wound therapy also significantly decreased the rate of surgical site infection in stoma patients (4 [30.7%] vs 9 [69.3%], P 1/4 .03).Conclusion: Open negative pressure wound therapy significantly decreases the incisional surgical site infection rate in patients with a dirty wound secondary to gastrointestinal perforation with peritonitis.& COPY; 2023 Elsevier Inc. All rights reserved.
C1 [Singh, Harjeet; Avudaiappan, Mohanasundaram; Kharel, Jyoti; Gupta, Vikas; Yadav, Thakur Deen; Gupta, Rajesh] Post Grad Inst Med Educ & Res, Dept Surg Gastroenterol, Chandigarh, India.
   [Irrinki, Santosh; Savlania, Ajay] Post Grad Inst Med Educ & Res, Dept Gen Surg, Chandigarh, India.
   [Kumar, Hemant] Manipal Hosp, Dept Surg Gastroenterol, Bangalore, India.
   [Sharma, Vishal] Post Grad Inst Med Educ & Res, Dept Gastroenterol, Chandigarh, India.
   [Singh, Harjeet] Post Grad Inst Med Educ & Res, Dept Surg Gastroenterol, Chandigarh 160012, India.
C3 Post Graduate Institute of Medical Education & Research (PGIMER),
   Chandigarh; Post Graduate Institute of Medical Education & Research
   (PGIMER), Chandigarh; Post Graduate Institute of Medical Education &
   Research (PGIMER), Chandigarh; Post Graduate Institute of Medical
   Education & Research (PGIMER), Chandigarh
RP Singh, H (通讯作者)，Post Grad Inst Med Educ & Res, Dept Surg Gastroenterol, Chandigarh 160012, India.
EM harjeetsingh1982@gmail.com
RI ; Sharma, Vishal/B-9729-2011; yadav, thakur/AAK-5537-2021; KUMAR,
   HEMANT/PII-7632-2026
OI Singh, Harjeet/0000-0002-0748-9473; Sharma, Vishal/0000-0003-2472-3409; 
FU Post Graduate Institute of Medical Education and Research, Chandigarh
FX The work was supported by an intramural research grant from the
   institute (Post Graduate Institute of Medical Education and Research,
   Chandigarh) for purchasing NPWT dressing. The funder has no role in
   designing, data collection, or analysis.
CR Barie PS, 2005, SURG CLIN N AM, V85, P1115, DOI 10.1016/j.suc.2005.09.006
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   BUCKNALL TE, 1982, BMJ-BRIT MED J, V284, P931, DOI 10.1136/bmj.284.6320.931
   Cohn SM, 2001, ANN SURG, V233, P409, DOI 10.1097/00000658-200103000-00016
   Danno K, 2018, SURG INFECT, V19, P711, DOI 10.1089/sur.2018.134
   Duttaroy DD, 2009, SURG INFECT, V10, P129, DOI 10.1089/sur.2007.030
   Frazee R, 2018, J AM COLL SURGEONS, V226, P507, DOI 10.1016/j.jamcollsurg.2017.12.008
   Grauhan O, 2013, J THORAC CARDIOV SUR, V145, P1387, DOI 10.1016/j.jtcvs.2012.09.040
   HORAN TC, 1992, AM J INFECT CONTROL, V20, P271, DOI 10.1016/S0196-6553(05)80201-9
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Javed AA, 2019, ANN SURG, V269, P1034, DOI 10.1097/SLA.0000000000003056
   Kugler NW, 2016, J SURG RES, V203, P491, DOI 10.1016/j.jss.2016.04.032
   Lahat G, 2005, Tech Coloproctol, V9, P206, DOI 10.1007/s10151-005-0228-z
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Ota H, 2020, J ANUS RECTUM COLON, V4, P114, DOI 10.23922/jarc.2019-043
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Siribumrungwong B, 2018, ANN SURG, V267, P631, DOI 10.1097/SLA.0000000000002464
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Tan A, 2014, INT J SURG, V12, P26, DOI 10.1016/j.ijsu.2013.11.002
   Watanabe M, 2014, SURG INFECT, V15, P256, DOI 10.1089/sur.2012.154
   Wechter ME, 2005, OBSTET GYNECOL, V106, P376, DOI 10.1097/01.AOG.0000171114.75338.06
   Yamamoto T, 2019, INT SURG, V104, P338, DOI 10.9738/INTSURG-D-17-00086.1
NR 23
TC 4
Z9 7
U1 0
U2 3
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
J9 SURGERY
JI Surgery
PD AUG
PY 2023
VL 174
IS 2
BP 291
EP 295
DI 10.1016/j.surg.2023.04.018
EA JUL 2023
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA P7YA4
UT WOS:001052779200001
PM 37183134
DA 2026-07-24
ER

PT J
AU Ferbert, T
   Kuhfuss, I
   Ziegler, UE
AF Ferbert, T
   Kuhfuss, I
   Ziegler, UE
TI Treatment of soft tissue defects on hand and forearm with vacuum
   assisted closure
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Country Congress on VAC Therapy for Outpatients as well as
   In-Hospital Patients
CY MAY 21-22, 2003
CL Mainz, GERMANY
DE vacuum assisted closure; installation; chronic wound
AB Vacuum assisted closure techniques cover the whole spectrum (VAC) of treatments in soft tissue defects, not only on the surface of the body. The combination of VAC and sharp debridement keep the principal of wound bed preparation. More and more clinical experience increases the options of this method (control of infection), reduction of oedema (pre- and postoperatively) and take rates of grafts. The vacuum-installation-technique offers new treatments in acute and chronic wounds.
C1 Chirurg Univ Klin Wurzburg, Plast Chirurg & Handchirurg, D-97080 Wurzburg, Germany.
C3 University of Wurzburg
RP Ziegler, UE (通讯作者)，Chirurg Univ Klin Wurzburg, Plast Chirurg & Handchirurg, Oberdurrbacher Str 6, D-97080 Wurzburg, Germany.
EM ulrich.ziegler@mail.uni-wuerzburg.de
NR 0
TC 1
Z9 1
U1 0
U2 2
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD MAY
PY 2004
VL 129
SU 1
BP S57
EP S58
DI 10.1055/s-2004-822667
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 826GF
UT WOS:000221816600018
PM 15168288
DA 2026-07-24
ER

PT J
AU DeFranzo, AJ
   Pitzer, K
   Molnar, JA
   Marks, MW
   Chang, MC
   Miller, PR
   Letton, RW
   Argenta, LC
AF DeFranzo, Anthony J.
   Pitzer, Keith
   Molnar, Joseph A.
   Marks, Malcolm W.
   Chang, Michael C.
   Miller, Preston R.
   Letton, Robert W.
   Argenta, Louis C.
TI Vacuum-assisted closure for defects of the abdominal wall
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article; Proceedings Paper
CT 73rd Annual Meeting of the American-Society-of-Plastic-Surgeons
CY OCT   17, 2004
CL Philadelphia, PA
SP Amer Soc Plast Surg
ID INJURED PATIENTS; RECONSTRUCTION; FLAP
AB Background: Reconstruction of the abdominal wall poses a problem common to many surgical specialties: Abdominal wall defects may be caused by trauma and/or prior surgery, with dehiscence or infection. Several options to repair the structural integrity of the abdominal wall exist, including primary closure, flaps, mesh, and skin grafts. Complications of these procedures include recurrent infection of the abdominal wall, infection of mesh, dehiscence, flap death, and poor skin graft take. Risk factors predisposing to these complications include tissue edema, preoperative tissue infection, and patient debilitation, with poor wound healing potential. Ideally, reconstruction should be performed on a nonedematous, clean tissue bed with bacterial levels less than 10(5) bacteria/cm(3) in a well-nourished patient.
   Methods: Vacuum-assisted closure was used in a series of patients in an attempt to prepare the abdominal wall for reconstruction and reduce the risk of complications. Charts were reviewed for 100 patients who underwent abdominal wall reconstruction after vacuum-assisted closure therapy. Their wound cause, reconstruction technique, complications, and number of days on the vacuum-assisted closure device are reported.
   Results: The ability of vacuum-assisted closure to reduce edema, increase blood flow, potentially decrease bacterial colonization, and reduce wound size greatly facilitated abdominal wall reconstruction. The vacuum-assisted closure device served as a temporary dressing with which to control dehiscence and to maintain abdominal wall integrity when bowel wall edema prevented abdominal closure.
   Conclusion: Vacuum-assisted closure therapy frequently shortened time to abdominal wall reconstruction and simplified the method of reconstruction.
C1 [DeFranzo, Anthony J.] Wake Forest Univ, Bowman Gray Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27157 USA.
   Wake Forest Univ, Bowman Gray Sch Med, Dept Gen Surg, Winston Salem, NC 27157 USA.
C3 Wake Forest University; Wake Forest Baptist Medical Center; Wake Forest
   University; Wake Forest Baptist Medical Center
RP DeFranzo, AJ (通讯作者)，Wake Forest Univ, Bowman Gray Sch Med, Dept Plast & Reconstruct Surg, Med Ctr Blvd, Winston Salem, NC 27157 USA.
EM adefranz@wfubmc.edu
RI Molnar, Joseph/AEK-5540-2022
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   Sukkar SM, 2001, AM J SURG, V181, P115, DOI 10.1016/S0002-9610(00)00566-3
   van Geffen HJAA, 2005, J AM COLL SURGEONS, V201, P206, DOI 10.1016/j.jamcollsurg.2005.03.030
   Wagner S, 2003, WOUND REPAIR REGEN, V11, P253, DOI 10.1046/j.1524-475X.2003.11404.x
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
NR 18
TC 36
Z9 49
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0032-1052
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD MAR
PY 2008
VL 121
IS 3
BP 832
EP 839
DI 10.1097/01.prs.0000299268.51008.47
PG 8
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 268GA
UT WOS:000253566000013
PM 18317132
DA 2026-07-24
ER

PT J
AU Tuncer, GK
   Tuncer, K
   Aydogan, S
AF Tuncer, Gizem Kilinc
   Tuncer, Korhan
   Aydogan, Serdar
TI Do Stoma Formation and Use of Vacuum Assisted Closure System Affect
   Mortality in Perineal Fournier's Gangrene?
SO JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
LA English
DT Article
DE Fournier?s gangrene; Vacuum-assisted closure system; Stoma; Anorectal
   region; Perineum; Mortality
ID MANAGEMENT
AB Objective: The aim of this study was to identify the effects of creation of stoma and the use of vacuum-assisted closure systems on postoperative mortality and hospital stay in patients with Fournier's gangrene involving anorectal region.Study Design: A retrospective study.Place and Duration of Study: Department of General Surgery, University of Health Sciences Tepecik Training and Research Hospital, Izmir, Turkey, from January 2010 to September 2021. Methodology: A total of 66 patients with Fournier's gangrene with anorectal involvement were selected from hospital records and divided into two groups as alive and exitus. Differences between these two groups and the factors affecting mortality were analysed with the SPSS statistics software, version 25.0. The value of p<0.05 was considered statistically significant.Results: The mean age of the patients was 57.9 +/- 12.9 years, however, age was higher in exitus group (p=0.013). Debridement count was significantly raised in patients with vacuum assisted closure system (p<0.001). The use of vacuum-assisted closure system was associated with a longer hospital stay (p=0.042). Both stoma creation and the use of vacuum-assisted closure system were not found as risk factors for higher mortality.Conclusion: Stoma creation and the use of vacuum-assisted closure systems have no effect on mortality in patients of Fournier's gangrene with anorectal involvement. Urogenital involvement may be considered as a risk factors for mortality.
C1 [Tuncer, Gizem Kilinc] Univ Hlth Sci, Bozyaka Training & Res Hosp, Dept Gen Surg, Izmir, Turkiye.
   [Tuncer, Korhan] Cigli Training & Res Hosp, Dept Gen Surg, Izmir, Turkiye.
   [Aydogan, Serdar] Univ Hlth Sci, Tepecik Training & Res Hosp, Dept Gen Surg, Izmir, Turkiye.
   [Tuncer, Gizem Kilinc] Bozyaka Training & Res Hosp, Dept Gen Surg, Saim Cikrikci St 56, TR-35170 Karabaglar, Turkiye.
C3 Izmir Bozyaka Training & Research Hospital; University of Health
   Sciences Turkey; University of Health Sciences Turkey; Izmir Tepecik
   Training & Research Hospital
RP Tuncer, GK (通讯作者)，Bozyaka Training & Res Hosp, Dept Gen Surg, Saim Cikrikci St 56, TR-35170 Karabaglar, Turkiye.
EM drgizemkilinc@gmail.com
RI Tuncer, Korhan/JAN-4676-2023; Kilinc Tuncer, Gizem/JXN-7091-2024
OI Kilinc Tuncer, Gizem/0000-0002-6987-3198
CR Akcan A, 2009, ULUS TRAVMA ACIL CER, V15, P342
   Carvalho Joao P., 2007, Int. braz j urol., V33, P510
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NR 15
TC 1
Z9 3
U1 0
U2 4
PU COLL PHYSICIANS & SURGEONS PAKISTAN
PI KARACHI
PA SEVENTH CENTRAL ST, DEFENCE HOUSING AUTHORITY, KARACHI, 75500, PAKISTAN
SN 1022-386X
EI 1681-7168
J9 JCPSP-J COLL PHYSICI
JI JCPSP-J. Coll. Physicians Surg.
PD FEB
PY 2023
VL 33
IS 2
BP 145
EP 148
DI 10.29271/jcpsp.2023.02.145
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA C8XA8
UT WOS:000964672800005
PM 36797621
OA gold
DA 2026-07-24
ER

PT J
AU Querings, K
   Bonowitz, A
   Dill-Müller, D
AF Querings, K
   Bonowitz, A
   Dill-Müller, D
TI Revitalization of a gluteal abscesses with VAC® therapy
   (vacuum assisted closure)
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Country Congress on VAC Therapy for Outpatients as well as
   In-Hospital Patients
CY MAY 21-22, 2003
CL Mainz, GERMANY
DE gluteal abszess; intramuscular injection; vacuum-assisted closure
AB Abscess formation is a frequent complication following gluteal injection. Septic abscesses as well as aseptic necrosis of muscle or subcutaneous adipose tissue require surgical management. We present a case of subcutaneous necrosis following gluteal injection in which vacuum-assisted closure (V.A.C.(R) therapy) has been effectively applied in the phase of secondary wound healing following surgical drainage. V.A.C.(R) therapy offers ambulatory management with optimal hygiene and patient's comfort.
C1 Univ Saarlandes Kliniken, Hautklin & Poliklin, D-66421 Homburg, Germany.
C3 Universitatsklinikum des Saarlandes
RP Querings, K (通讯作者)，Univ Saarlandes Kliniken, Hautklin & Poliklin, D-66421 Homburg, Germany.
EM K.Querings@gmx.de
CR Abdelwahab IF, 1998, SKELETAL RADIOL, V27, P36, DOI 10.1007/s002560050333
   AHMED ME, 1989, J TROP MED HYG, V92, P317
   Bosscha K, 2002, Ned Tijdschr Geneeskd, V146, P649
   ZUBER M, 1987, SCHWEIZ MED WSCHR, V117, P328
NR 4
TC 0
Z9 0
U1 0
U2 0
PU JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
PI STUTTGART
PA RUEDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD MAY
PY 2004
VL 129
SU 1
BP S138
EP S140
DI 10.1055/s-2004-822661
PG 3
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 826GF
UT WOS:000221816600043
PM 15168313
DA 2026-07-24
ER

PT J
AU Davey, MG
   Donlon, NE
   Walsh, SR
   Donohoe, CL
AF Davey, Matthew G.
   Donlon, Noel E.
   Walsh, Stewart R.
   Donohoe, Claire L.
CA PROPEL 2 Trial Collaborators
TI Prophylactic negative pressure wound therapy (NPWT) in laparotomy wounds
   (PROPEL-2): protocol for a randomized clinical trial
SO BJS OPEN
LA English
DT Article
ID SURGICAL SITE INFECTION; PREVENTION; SURGERY; EPIDEMIOLOGY; COST
AB Background A proportion of patients undergoing midline laparotomy will develop surgical site infections after surgery. These complications place considerable financial burden on healthcare economies and have negative implications for patient health and quality of life. The prophylactic application of negative pressure wound therapy devices has been mooted as a pragmatic strategy to reduce surgical site infections. Nevertheless, further availability of multicentre randomized clinical trial data evaluating the prophylactic use of negative pressure wound therapy following midline laparotomy is warranted to definitely provide consensus in relation to these closure methods, while also deciphering potential differences among subgroups. The aim of this study is to determine whether prophylactic negative pressure wound therapy reduces postoperative wound complications in patients undergoing midline laparotomy.Methods PROPEL-2 is a multicentre prospective randomized clinical trial designed to compare standard surgical dressings (control arm) with negative pressure wound therapy dressings (Prevena (TM) and PICO (TM) being the most commonly utilized). Patient recruitment will include adult patients aged 18 years or over, who are indicated to undergo emergency or elective laparotomy. To achieve 90% power at the 5% significance level, 1006 patients will be required in each arm, which when allowing for losses to follow-up, 10% will be added to each arm, leaving the total projected sample size to be 2013 patients, who will be recruited across a 36-month enrolment period.Conclusion The PROPEL-2 trial will be the largest independent multicentre randomized clinical trial designed to assess the role of prophylactic negative pressure wound therapy in patients indicated to undergo midline laparotomy. The comparison of standard treatment to two commercially available negative pressure wound therapy devices will help provide consensus on the routine management of laparotomy wounds. Enrolment to PROPEL-2 began in June 2023. Registration number: NCT05977816 (http://www.clinicaltrials.gov).Conclusion The PROPEL-2 trial will be the largest independent multicentre randomized clinical trial designed to assess the role of prophylactic negative pressure wound therapy in patients indicated to undergo midline laparotomy. The comparison of standard treatment to two commercially available negative pressure wound therapy devices will help provide consensus on the routine management of laparotomy wounds. Enrolment to PROPEL-2 began in June 2023. Registration number: NCT05977816 (http://www.clinicaltrials.gov).
   The PROPEL-2 prospective, randomized study looking to evaluate the role of negative pressure wound therapy for laparotomy wounds.
C1 [Davey, Matthew G.; Donlon, Noel E.; Walsh, Stewart R.; Donohoe, Claire L.] Royal Coll Surgeons Ireland, Dept Surg Affairs, 121 St Stephens Green, Dublin, Ireland.
   [Davey, Matthew G.; Donlon, Noel E.; Walsh, Stewart R.; Donohoe, Claire L.] Natl Surg Res Support Ctr NSRSC, Dublin, Ireland.
C3 Royal College of Surgeons in Ireland - RCSI
RP Davey, MG (通讯作者)，Royal Coll Surgeons Ireland, Dept Surg Affairs, 121 St Stephens Green, Dublin, Ireland.
EM matthewdavey21@rcsi.ie
RI Davey, Matthew/ABF-8533-2021; Walsh, Stewart/AFZ-2791-2022; Donohoe,
   Claire/AAG-4770-2019
OI Wang, Shuang/0009-0005-5511-8027; Walsh, Stewart/0000-0002-1006-9541;
   Donohoe, Claire/0000-0001-9373-2662
FU Royal College of Surgeons in Ireland-National Surgical Research Support
   Centre (RCSI-NSRSC)
FX Funding support provided by the Royal College of Surgeons in
   Ireland-National Surgical Research Support Centre (RCSI-NSRSC).
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NR 43
TC 3
Z9 3
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 2474-9842
J9 BJS OPEN
JI BJS Open
PD AUG 23
PY 2024
VL 8
IS 4
AR zrae081
DI 10.1093/bjsopen/zrae081
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA D5B9O
UT WOS:001296345500001
PM 39178168
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Bonnamy, C
   Hamel, F
   Leporrier, J
   Fouques, Y
   Viquesnel, G
   Le Roux, Y
AF Bonnamy, C
   Hamel, F
   Leporrier, J
   Fouques, Y
   Viquesnel, G
   Le Roux, Y
TI Vacuum-assisted closure in the treatment of a perineal gangrene extended
   to the abdominal wall.
SO ANNALES DE CHIRURGIE
LA French
DT Article
DE perineal gangrene; vacuum-assisted closure
AB The vacuum-assisted closure (VAC) system is used for the treatment of complicated wounds and large tissular dehiscences. The study aim was to report a case of perineal gangrene extended to the abdominal wall in a 53-year old woman. After several extensive surgical debridments, using of the VAC was followed by a good and rapid healing of the wound. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
C1 CHU Caen, Dept Chirurg Gen & Digest, F-14033 Caen, France.
   CHU Caen, Dept Anesthesie Reanimat, F-14033 Caen, France.
C3 CHU de Caen NORMANDIE; Universite de Caen Normandie; Universite de Caen
   Normandie; CHU de Caen NORMANDIE
RP Bonnamy, C (通讯作者)，CHU Caen, Dept Chirurg Gen & Digest, Ave Cote Nacre, F-14033 Caen, France.
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NR 7
TC 12
Z9 19
U1 0
U2 2
PU ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
PI ISSY-LES-MOULINEAUX
PA 65 RUE CAMILLE DESMOULINS, CS50083, 92442 ISSY-LES-MOULINEAUX, FRANCE
SN 0003-3944
J9 ANN CHIR
JI Ann. Chir.
PD DEC
PY 2000
VL 125
IS 10
BP 982
EP 984
DI 10.1016/S0003-3944(00)00411-9
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 387PT
UT WOS:000166131500010
PM 11195929
DA 2026-07-24
ER

PT J
AU Gruzmark, FS
   Kirsner, RS
   Jaller, JA
AF Gruzmark, Fiona S.
   Kirsner, Robert S.
   Jaller, Jose A.
TI Combining Acellular Dermal Grafts With Negative-Pressure Wound Therapy
   in a Postsurgical Wound: A Case Report
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
DE acellular dermal graft; extracellular matrix graft; Mohs micrographic
   surgery; negative pressure wound therapy; ulcer; wound
ID MOHS MICROGRAPHIC SURGERY
AB Chronic wounds are expensive and burdensome to the health care system, with some acute wounds, such as wounds after Mohs micrographic surgery (MMS), contributing to this problem. The rate of MMS performed is increasing, and if they become nonhealing, they can be challenging to treat and necessitate proper care. Both acellular dermal grafts and negative-pressure wound therapy are therapies that can be used to treat complicated wounds, but the combination of these 2 therapies has not been extensively studied. The study authors report the successful use of an acellular dermal graft in combination with negative pressure wound therapy in healing a complicated post-MMS wound on the thigh.
C1 [Gruzmark, Fiona S.; Kirsner, Robert S.; Jaller, Jose A.] Univ Miami, Miller Sch Med, Dr Phillip Frost Dept Dermatol & Cutaneous Surg, Miami, FL USA.
   [Kirsner, Robert S.] Univ Miami, Miller Sch Med, Dept Publ Hlth Sci, Miami, FL USA.
   [Gruzmark, Fiona S.; Kirsner, Robert S.] Univ Miami Hosp & Clin Wound Ctr, 1600 NW 10th Ave,Suite 1149, Miami, FL 33136 USA.
   [Gruzmark, Fiona S.; Kirsner, Robert S.] Univ Miami Hosp, 1600 NW 10th Ave,Suite 1149, Miami, FL 33136 USA.
   [Gruzmark, Fiona S.; Kirsner, Robert S.] Univ Miami, Jackson Mem Hosp, Wound Clin, 1600 NW 10th Ave,Suite 1149, Miami, FL 33136 USA.
C3 University of Miami; University of Miami; University System of Ohio;
   Miami University; University of Miami
RP Gruzmark, FS (通讯作者)，Univ Miami Hosp & Clin Wound Ctr, 1600 NW 10th Ave,Suite 1149, Miami, FL 33136 USA.; Gruzmark, FS (通讯作者)，Univ Miami Hosp, 1600 NW 10th Ave,Suite 1149, Miami, FL 33136 USA.; Gruzmark, FS (通讯作者)，Univ Miami, Jackson Mem Hosp, Wound Clin, 1600 NW 10th Ave,Suite 1149, Miami, FL 33136 USA.; Gruzmark, FS (通讯作者)，Univ Miami, Dr Phillip Frost Dept Dermatol & Cutaneous Surg, Dept Publ Hlth Sci, Miller Sch Med, 1600 NW 10th Ave,Suite 1149, Miami, FL 33136 USA.
EM fsg28@miami.edu; rkirsner@med.miami.edu; jjaller@med.miami.edu
RI Jaller, Jose/K-2567-2019
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NR 21
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD MAY
PY 2026
VL 39
IS 4
BP E194
EP E196
DI 10.1097/ASW.0000000000000435
PG 3
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA GS6PH
UT WOS:001744100500014
PM 41920930
DA 2026-07-24
ER

PT J
AU Chadi, SA
   Kidane, B
   Britto, K
   Brackstone, M
   Ott, MC
AF Chadi, Sami A.
   Kidane, Biniam
   Britto, Karen
   Brackstone, Muriel
   Ott, Michael C.
TI Incisional Negative Pressure Wound Therapy Decreases the Frequency of
   Postoperative Perineal Surgical Site Infections: A Cohort Study
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article
DE Colon and rectal surgery; Abdominoperineal resection; Incisional
   negative pressure wound therapy; Wound closure
ID ABDOMINOPERINEAL RESECTION; RISK-FACTORS; PRIMARY CLOSURE;
   RECTAL-CANCER; CARCINOMA; COMPLICATIONS; PREVENTION; SURGERY;
   MANAGEMENT; EXCISION
AB BACKGROUND: Abdominoperineal resection is a procedure associated with high rates of perineal surgical site infections, causing distress to the patient, costs to the hospital system, and delays in further treatment.
   OBJECTIVE: The aim of this study was to investigate the role of incisional negative pressure wound therapy in decreasing the rates of perineal surgical site infection.
   DESIGN: This retrospective cohort study had a historical, consecutively sampled control group.
   SETTINGS: This study was conducted at a single-institution tertiary care academic institution.
   PATIENTS: All patients undergoing an abdominoperineal resection between 2008 and 2012 were assessed.
   INTERVENTIONS: Perineal incisional negative pressure wound therapy was applied to all patients following an abdominoperineal resection between 2010 and 2012 at 125 mmHg continuous suction for 5 days postoperatively.
   MAIN OUTCOME MEASURES: The development of a perineal surgical site infection within the first 30 days postoperatively was the primary outcome measured.
   RESULTS: Fifty-nine patients were included: 27 in the incisional negative pressure wound therapy group and 32 in the control group. A statistically lower proportion of perineal surgical site infections were detected in the incisional negative pressure wound therapy group than in the standard dressing group (15% vs 41%; p = 0.02). Both populations were similar in perioperative risk factors, with the exception of increased levels of blood urea nitrogen, a higher proportion of hypertensive patients, and a longer mean operative time in the incisional negative pressure wound therapy group. Additionally, an increased length of stay was observed in the incisional negative pressure wound therapy group (11 vs 8 days; p = 0.03). After adjusting for confounders, including the type of perineal dissection, incisional negative pressure wound therapy was found to be an independent predictor of not developing an surgical site infection (adjusted OR, 0.11; 95% CI, 0.04-0.66; p = 0.01).
   LIMITATIONS: The study's retrospective nature limits the results because of the risk of interpreter bias, although this was addressed in part by reviewing data in duplicate. We controlled for the potential for selection bias with our consecutive sampling model.
   CONCLUSIONS: Our study demonstrates a role for incisional negative pressure wound therapy in decreasing rates of perineal surgical site infection following abdominoperineal resection. Prospective randomized trials will be required to further investigate this intervention.
C1 [Chadi, Sami A.; Kidane, Biniam; Brackstone, Muriel; Ott, Michael C.] London Hlth Sci Ctr, Div Gen Surg, London, ON, Canada.
   [Chadi, Sami A.; Britto, Karen; Brackstone, Muriel; Ott, Michael C.] Western Univ, Schulich Sch Med & Dent, London, ON N6A 5W9, Canada.
C3 London Health Sciences Centre; Western University (University of Western
   Ontario)
RP Ott, MC (通讯作者)，Western Univ, Schulich Sch Med & Dent, London Hlth Sci Ctr, Victoria Campus,800 Commissioners Rd,E2-211, London, ON N6A 5W9, Canada.
EM michael.ott@lhsc.on.ca
RI Chadi, Sami/DWM-5165-2022
OI Kidane, Biniam/0000-0002-2982-2505; Ott, Michael/0000-0002-0816-7089
CR Artioukh DY, 2007, COLORECTAL DIS, V9, P362, DOI 10.1111/j.1463-1318.2006.01159.x
   Blackham AU, 2013, AM J SURG, V205, P647, DOI 10.1016/j.amjsurg.2012.06.007
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   Kao LS, 2011, J AM COLL SURGEONS, V213, P231, DOI 10.1016/j.jamcollsurg.2011.04.004
   Konishi T, 2006, ANN SURG, V244, P758, DOI 10.1097/01.sla.0000219017.78611.49
   Mark KS, 2014, SURG INNOV, V21, P345, DOI 10.1177/1553350613503736
   Miles WE, 1908, LANCET, V2, P1812, DOI 10.1016/s0140-6736(00)99076-7
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   Wiatrek Rebecca L, 2008, Clin Colon Rectal Surg, V21, P76, DOI 10.1055/s-2008-1055325
NR 23
TC 55
Z9 74
U1 0
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD AUG
PY 2014
VL 57
IS 8
BP 999
EP 1006
DI 10.1097/DCR.0000000000000161
PG 8
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA AL6KO
UT WOS:000339241500013
PM 25003295
DA 2026-07-24
ER

PT J
AU Yoong, S
   Dunne, G
   Cochrane, J
   Lee, B
   Lee, J
AF Yoong, Susan
   Dunne, Gillian
   Cochrane, Janette
   Lee, Bernard
   Lee, Jack
TI Vacuum-assisted closure for the treatment of parastomal skin necrosis: A
   novel approach to an unusual complication. Report of a case
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article
DE vacuum-assisted closure; parastomal skin necrosis; parastomal
   complication
AB Extensive peristomal skin necrosis is an unusual complication, which is difficult to manage because of frequent contamination from the stoma site. This wound leads to difficulty in applying the stoma appliance. This case report describes the successful use of the vacuum-assisted closure system in the management of a patient who developed peristomal skin necrosis after emergency Hartmann's procedure.
C1 [Yoong, Susan; Lee, Bernard; Lee, Jack] Belfast City Hosp Trust, Dept Surg, Belfast BT9 7AB, Antrim, North Ireland.
   [Dunne, Gillian; Cochrane, Janette] Belfast City Hosp Trust, Dept Tissue Viabil, Belfast BT9 7AB, Antrim, North Ireland.
C3 Belfast City Hospital; Belfast City Hospital
RP Lee, J (通讯作者)，Belfast City Hosp Trust, Dept Surg, Level 2, Belfast BT9 7AB, Antrim, North Ireland.
EM jack.lee@bch.n-i.nhs.uk
CR Ljung T, 2002, SCAND J GASTROENTERO, V37, P1108, DOI 10.1080/003655202320378338
   Moues C M, 2005, J Wound Care, V14, P224
   Rolstad Bonnie Sue, 2004, Ostomy Wound Manage, V50, P68
   Shellito PC, 1998, DIS COLON RECTUM, V41, P1562, DOI 10.1007/BF02237308
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
NR 5
TC 2
Z9 2
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0012-3706
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD OCT
PY 2008
VL 51
IS 10
BP 1577
EP 1579
DI 10.1007/s10350-008-9240-5
PG 3
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 352RD
UT WOS:000259514200023
PM 18330646
DA 2026-07-24
ER

PT J
AU Stanger, KM
   Albert, F
   Kneser, U
   Bogdan, C
   Horch, RE
AF Stanger, Katrin M.
   Albert, Frauke
   Kneser, Ulrich
   Bogdan, Christian
   Horch, Raymund E.
TI Management of chronic osteomyelitis of the tibia with life-threatening
   complications under negative pressure wound therapy and isolation of
   Helcococcus kunzii
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Free flap; Helcococcus kunzii; Marjolin ulcer; Negative pressure wound
   therapy; Wound infection
ID PROSTHETIC JOINT INFECTION; SKIN; ABSCESS; GRAFT
AB We report the case of an 86-year-old man with severe wound infection originating from a chronic crural ulcer of the lower limb, which under negative pressure wound therapy led to excessive tissue necrosis and perforation of the anterior tibial artery. A swab taken 10 and 7 days preoperatively was positive for Helcococcus kunzii. H. kunzii has been described as a potentially pathogenic organism. The questions whether the negative pressure wound therapy itself caused the bleeding or the negative pressure wound therapy, which generates an anaerobic atmosphere, has triggered the growth and invasion of the facultative anaerobic bacterium H. kunzii and owing to the infection the artery perforated or whether the bacteria has no influence at all remain currently unanswered. After surgical debridement the signs of infection were completely eliminated, and a free musculocutaneous flap led to rapid healing of the wound. Following which H. kunzii was no longer detectable.
C1 [Stanger, Katrin M.; Horch, Raymund E.] Univ Erlangen Nurnberg, Dept Plast & Hand Surg, Univ Hosp Erlangen, D-91054 Erlangen, Germany.
   [Albert, Frauke; Bogdan, Christian] Univ Erlangen Nurnberg, Univ Hosp Erlangen, Inst Microbiol, Clin Microbiol Immunol & Hyg, D-91054 Erlangen, Germany.
   [Kneser, Ulrich] Heidelberg Univ, Dept Plast & Hand Surg, Dept Hand Plast & Reconstruct Surg, Burn Ctr,BG Trauma Ctr Ludwigshafen, Heidelberg, Germany.
C3 University of Erlangen Nuremberg; University of Erlangen Nuremberg;
   Ruprecht Karls University Heidelberg
RP Stanger, KM (通讯作者)，Univ Klinikum Erlangen, Plast & Handchirurg Klin, Krankenhausstr 12, D-91054 Erlangen, Germany.
EM km@stangermail.de
RI Horch, Raymund E/H-8128-2019
OI Horch, Raymund E/0000-0002-6561-2353; Bogdan,
   Christian/0000-0002-2300-0631
CR Bleiziffer O, 2011, J CELL MOL MED, V15, P2452, DOI 10.1111/j.1582-4934.2010.01247.x
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NR 29
TC 12
Z9 14
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD AUG
PY 2015
VL 12
IS 4
BP 443
EP 446
DI 10.1111/iwj.12133
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CM2OI
UT WOS:000357520400012
PM 23855685
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Wang, ZH
   Qu, WQ
   Liu, T
   Zhou, ZY
   Zhao, ZY
   Wang, D
   Cheng, LM
AF Wang, Zhenhai
   Qu, Wenqing
   Liu, Tong
   Zhou, Zhiyong
   Zhao, Zhongyuan
   Wang, Dan
   Cheng, Limin
TI A Two-Stage Protocol With Vacuum Sealing Drainage for the Treatment of
   Type C Pilon Fractures
SO JOURNAL OF FOOT & ANKLE SURGERY
LA English
DT Article
DE anteromedial incision; pilon fracture; staged surgery; tibia; vacuum
   seal
ID TIBIAL PLAFOND FRACTURES; INTERNAL-FIXATION; OPERATIVE TREATMENT; OPEN
   REDUCTION
AB Management of type C pilon fractures remains controversial and challenging. The aim of the present study was to provide a 2-stage protocol with vacuum sealing drainage for the treatment of type C pilon fractures. From March 2009 to March 2012, 16 patients (mean age 42.3 years) were admitted to our department with type C pilon fractures and treated with single-stage external fixation and second-stage internal fixation (anteromedial incision) combined with vacuum sealing drainage. The American Orthopaedic Foot and Ankle Society scale score averaged 86.5 for this group of patients. The range of motion was 30 degrees +/- 8.9 degrees. An excellent or good American Orthopaedic Foot and Ankle Society scale score was obtained for all patients. None of the 16 patients developed skin necrosis, nonunion, or fixation failure during the follow-up period. Moreover, the visual analog scale pain scores were 0.7 +/- 0.8, 0.9 +/- 0.7, and 1.4 +/- 1.0 during rest, active movement, and weightbearing, respectively. The postoperative radiographs showed excellent treatment effects. A 2-stage protocol, combined with vacuum sealing drainage, for the treatment of type C pilon fractures can eliminate deep infection and complex surgery and is a simple and effective treatment method. In addition, full exposure of the anteromedial incision, the avoidance of the anterior tibial muscle tendon sheath, and the avoidance of soft tissue injuries are generally recommended in this operation. (C) 2016 by the American College of Foot and Ankle Surgeons. All rights reserved.
C1 [Wang, Zhenhai; Qu, Wenqing; Liu, Tong; Zhou, Zhiyong; Zhao, Zhongyuan; Wang, Dan; Cheng, Limin] Yantaishan Hosp, Dept Orthopaed & Trauma, Yantai, Peoples R China.
   [Wang, Zhenhai; Qu, Wenqing; Liu, Tong; Zhou, Zhiyong; Zhao, Zhongyuan; Wang, Dan; Cheng, Limin] Yantai Sino French Friendship Hosp, Dept Orthopaed & Trauma, Yantai, Peoples R China.
RP Wang, ZH (通讯作者)，Yantai Sino French Friendship Hosp, Dept Orthopaed & Trauma, Yantaishan Hosp, Yantai 264000, Peoples R China.
EM ytzhenhai@163.com
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NR 20
TC 16
Z9 24
U1 0
U2 12
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1067-2516
EI 1542-2224
J9 J FOOT ANKLE SURG
JI J. Foot Ankle Surg.
PD SEP-OCT
PY 2016
VL 55
IS 5
BP 1117
EP 1120
DI 10.1053/j.jfas.2016.01.047
PG 4
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA DU5MY
UT WOS:000382257000050
PM 26994675
DA 2026-07-24
ER

PT J
AU Wackenfors, A
   Gustafsson, R
   Sjögren, J
   Algotsson, L
   Ingemansson, R
   Malmsjö, M
AF Wackenfors, A
   Gustafsson, R
   Sjögren, J
   Algotsson, L
   Ingemansson, R
   Malmsjö, M
TI Blood flow responses in the peristernal thoracic wall during
   vacuum-assisted closure therapy
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID STERNAL WOUND-INFECTION; TISSUE OXYGEN-TENSION; POSTSTERNOTOMY
   MEDIASTINITIS; POSTOPERATIVE-PATIENTS; MACROPHAGES; PERFUSION; DEEP;
   ANGIOGENESIS; EXPERIENCE; LACTATE
AB Background. Vacuum-assisted closure (VAC) therapy is a recently introduced method for the treatment of poststernotomy mediastinitis. The aim of this study was to examine the effects of negative pressure on peristernal soft tissue blood flow and metabolism because the mechanisms by which vacuum-assisted closure therapy promotes wound healing are not known in detail.
   Methods. Microvascular blood flow was examined by laser Doppler velocimetry in an uninfected porcine sternotomy wound model. Microvascular blood flow was examined in the muscular and subcutaneous tissue, at different distances from the wound edge, after the application of -50 to -200 mm Hg. Wound fluid pH, partial pressures of oxygen and carbon dioxide, bicarbonate, and lactate were analyzed after 0, 30, and 60 minutes of continuous negative pressure.
   Results. Vacuum-assisted closure therapy induced an increase in the microvascular blood flow a few centimeters from the wound edge. In muscular tissue, the distance from the wound edge to the position at which the blood flow was increased was shorter than that in subcutaneous tissue. Close to the wound edge, relative hypoperfusion was observed. The hypoperfused zone was larger at high negative pressures and was especially prominent in subcutaneous tissue. Wound fluid partial pressure of oxygen and lactate levels were increased after 60 minutes of vacuum-assisted closure therapy, which may be the result of changes in the microvascular blood flow.
   Conclusions. Vacuum-assisted closure therapy induces a change in microvascular blood flow that is dependent on the pressure applied, the distance from the wound edge, and the tissue type. It may be beneficial to tailor the negative pressure used for vacuum-assisted closure therapy according to the wound tissue composition. Wound fluid partial pressure of oxygen and lactate levels increased during vacuum-assisted closure therapy. This combination is known to promote wound healing. © 2005 by The Society of Thoracic Surgeons.
C1 Univ Lund Hosp, Dept Internal Med, S-22185 Lund, Sweden.
   Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden.
   Univ Lund Hosp, Dept Cardiothorac Anesthesia, S-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital; Lund University; Skane University Hospital
RP Wackenfors, A (通讯作者)，BMC, Expt Vasc Res, BMC A13, SE-22184 Lund, Sweden.
EM angelica.wackenfors@med.lu.se
RI ; Sjögren, Johan/AAZ-6448-2021
OI Ingemansson, Richard/0000-0001-7623-8953; Maljö,
   Malin/0000-0001-9849-9599; 
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NR 29
TC 184
Z9 210
U1 0
U2 12
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD MAY
PY 2005
VL 79
IS 5
BP 1724
EP 1731
DI 10.1016/j.athoracsur.2004.10.053
PG 8
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 922YR
UT WOS:000228876300041
PM 15854963
DA 2026-07-24
ER

PT J
AU Cho, HS
   Kim, MS
   Lee, C
   Ahn, HY
AF Cho, Ho Seong
   Kim, Min Su
   Lee, Chiseung
   Ahn, Hyo Yeong
TI Modified Negative Pressure Wound Therapy Using Surgical Drain and
   Occlusive Sutures for Leakage After Esophageal Injury
SO INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE esophageal injury; negative pressure wound therapy; anastomotic leakage
ID MANAGEMENT
AB Oesophageal leakage is a serious complication that can lead to infection, sepsis, malnutrition, and death. Negative Pressure Wound Therapy has been increasingly used to treat oesophageal leaks; however, in cases of cervical oesophageal leakage, deep tract and anatomical complexity often hinder an airtight seal and limit transmission of negative pressure. We developed a modified Negative Pressure Wound Therapy technique by connecting a surgical drain to the base of the foam dressing and securing it with subcutaneous occlusive sutures to ensure a reliable seal and effective negative pressure transmission. Four cases of modified application were included in this study. All leaks were controlled without complications attributable to the procedure. The modified Negative Pressure Wound Therapy technique effectively addresses the limitations of conventional methods in complex anatomical regions. By ensuring a reliable occlusive seal and enhancing negative pressure transmission, this approach promotes optimal wound healing through improved exudate clearance and reduced maceration.
   Oesophageal leakage has multiple etiologies, especially due to anastomotic leakage or oesophageal injury.
C1 [Cho, Ho Seong; Ahn, Hyo Yeong] Pusan Natl Univ, Pusan Natl Univ Hosp, Sch Med, Dept Thorac & Cardiovasc Surg, Pusan 49241, South Korea.
   [Cho, Ho Seong; Lee, Chiseung; Ahn, Hyo Yeong] Pusan Natl Univ Hosp, Biomed Res Inst, Pusan 49241, South Korea.
   [Kim, Min Su] Pusan Natl Univ, Grad Sch, Dept Biomed Engn, Busan 49241, South Korea.
   [Lee, Chiseung] Pusan Natl Univ, Sch Med, Dept Biomed Engn, Pusan 49241, South Korea.
C3 Pusan National University; Pusan National University Hospital; Pusan
   National University; Pusan National University Hospital; Pusan National
   University; Pusan National University
RP Ahn, HY (通讯作者)，Pusan Natl Univ, Pusan Natl Univ Hosp, Med Res Inst, Coll Med,Dept Thorac & Cardiovasc Surg, 179 Gudeok Ro, Busan 49241, South Korea.
EM doctorahn02@hanmail.net
OI Ahn, Hyo Yeong/0000-0003-3198-8237; Cho, Ho Seong/0000-0002-9512-8909
FU National Research Foundation of Korea (NRF) [RS-2023-00252649]
FX None declared.
CR Evans RPT, 2020, DIS ESOPHAGUS, V33, DOI 10.1093/dote/doz007
   Housman B, 2021, J SURG ONCOL, V124, P529, DOI 10.1002/jso.26550
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NR 7
TC 0
Z9 0
U1 1
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
EI 2753-670X
J9 INTERDISC CARDIOV TH
JI Interdiscip. Cardiovasc. Thorac. Surg.
PD JAN
PY 2026
VL 41
IS 1
AR ivaf296
DI 10.1093/icvts/ivaf296
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA AR1RQ
UT WOS:001654794000001
PM 41346261
OA gold
DA 2026-07-24
ER

PT J
AU Huang, ZG
   Lei, C
   Zhang, L
   Xue, HD
   Shen, J
   Wu, SY
   Wang, B
   Chen, JW
AF Huang, Zugen
   Lei, Chen
   Zhang, Ling
   Xue, Huadong
   Shen, Jian
   Wu, Shanying
   Wang, Biao
   Chen, Jianwu
TI Negative Pressure Wound Therapy With Chymotrypsin Irrigation: A Maximal
   Implant Retention Procedure Treating the Exposure/Infection of Titanium
   Mesh in Cranioplasty
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Chymotrypsin; cranioplasty; implant-related infection; negative pressure
   wound therapy; titanium mesh
ID RETROSPECTIVE ANALYSIS; SCALP THICKNESS; COMPLICATIONS; INFECTION;
   INSTILLATION; COST; RISK; TIME
AB This preliminary study aims to investigate the effects of a maximal implant retention procedure. The authors retrospectively reviewed the use of negative pressure wound therapy with chymotrypsin irrigation treating implant infection/exposure in titanium mesh cranioplasty by comparing patients with titanium mesh totally retained, partially removed, or totally removed according to the evaluation during the surgery. Negative pressure wound therapy with chymotrypsin irrigation was applied 5 days after the surgery. The negative pressure was set at -125 to -150 mmHg. A total of 21 patients were included, 4 patients treated with titanium mesh totally removed; 3 patients treated with titanium mesh partially removed; and 14 patients treated with U-shape debridement with titanium mesh preserved completely. However, 1 patient in the U-shape group required a second debridement to remove all implant. Negative pressure wound therapy with chymotrypsin irrigation is a novel procedure and could be used to treat implant-related infection without the exchange of implant.
C1 [Huang, Zugen; Lei, Chen; Zhang, Ling; Xue, Huadong; Shen, Jian; Wu, Shanying; Wang, Biao] Fujian Med Univ, Dept Plast Surg, Affiliated Hosp 1, Fuzhou, Fujian, Peoples R China.
   [Chen, Jianwu] Fujian Med Univ, Dept Neurosurg, Affiliated Hosp 1, Fuzhou, Fujian, Peoples R China.
C3 Fujian Medical University; Fujian Medical University
RP Wang, B (通讯作者)，Fujian Med Univ, Dept Plast Surg, Affiliated Hosp 1, Fuzhou, Fujian, Peoples R China.; Chen, JW (通讯作者)，Fujian Med Univ, Dept Neurosurg, Affiliated Hosp 1, Fuzhou, Fujian, Peoples R China.
EM 1812166371@qq.com; fzcjw@sina.com
RI Zhang, LingKang/KYQ-2776-2024
FU Natural Science Foundation of China [81801931]; Fujian Provincial Key
   Clinical Specialty Discipline Construction Program [2016-SLCZD]; Fujian,
   Provincial Natural Science Foundation Program [2018J01154, 2018J01163];
   Project of the Maxillofacial Medical Center in Fujian Province, Start-up
   Foundation of Fujian Medical University [2017XQ1059]; Scientific
   Research Foundation of National Health Planning Scientific Research
   Foundation-Joint Research Projects of Fujian Provincial Health and
   Education [2019-WJ-09]; Special Supported Funds of Fujian Provincial
   Finance Department [BPB-WB2016]
FX This work was supported by the Natural Science Foundation of China
   (81801931), Fujian Provincial Key Clinical Specialty Discipline
   Construction Program (2016-SLCZD), Fujian, Provincial Natural Science
   Foundation Program (2018J01154, 2018J01163), the Project of the
   Maxillofacial Medical Center in Fujian Province, Start-up Foundation of
   Fujian Medical University (2017XQ1059). Scientific Research Foundation
   of National Health Planning Scientific Research Foundation-Joint
   Research Projects of Fujian Provincial Health and Education
   (2019-WJ-09). Special Supported Funds of Fujian Provincial Finance
   Department (BPB-WB2016).
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NR 38
TC 4
Z9 5
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD MAR-APR
PY 2020
VL 31
IS 2
BP 522
EP 526
DI 10.1097/SCS.0000000000006214
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA LI3AC
UT WOS:000529353700096
PM 31977700
DA 2026-07-24
ER

PT J
AU Chiarello, MM
   Brisinda, G
AF Chiarello, Maria Michela
   Brisinda, Giuseppe
TI A Commentary on "Prophylactic negative pressure wound therapy for closed
   laparotomy incision after ventral hernia repair: A systematic review and
   meta-analysis" (Int J Surg 2022; 97:106216)
SO INTERNATIONAL JOURNAL OF SURGERY
LA English
DT Editorial Material
DE Ventral hernia; Prophylactic negative pressure wound therapy; Surgical
   site infection
ID ABDOMINAL-WALL RECONSTRUCTION; RETROSPECTIVE COHORT ANALYSIS;
   PERIOPERATIVE COMPLICATIONS; BIOLOGIC MESH
C1 [Chiarello, Maria Michela] Azienda Sanitaria Prov Cosenza, Osped San Giovanni Fiore, Gen Surg Operat Unit, Cosenza, Italy.
   [Brisinda, Giuseppe] Univ Cattolica Sacro Cuore, Rome, Italy.
   [Brisinda, Giuseppe] Fdn Policlin Univ A Gemelli, Dept Surg, IRCCS, Largo Agostino Gemelli 8, IT-00168 Rome, Italy.
C3 Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli;
   Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli
RP Brisinda, G (通讯作者)，Fdn Policlin Univ A Gemelli, Dept Surg, IRCCS, Largo Agostino Gemelli 8, IT-00168 Rome, Italy.
EM giuseppe.brisinda@policlinicogemelli.it
RI chiarello, MARIA MICHELA/GVS-7109-2022; Brisinda, Giuseppe/G-6436-2010
OI chiarello, MARIA MICHELA/0000-0003-3455-0062; Brisinda,
   Giuseppe/0000-0001-8820-9471
CR Chiarello MM, 2020, INT J SURG, V76, P14, DOI 10.1016/j.ijsu.2020.02.002
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   Kääriäinen M, 2017, SCAND J SURG, V106, P145, DOI 10.1177/1457496916665542
   Latifi R, 2020, INT J SURG, V74, P94, DOI 10.1016/j.ijsu.2019.12.035
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NR 9
TC 0
Z9 0
U1 0
U2 3
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 1743-9191
EI 1743-9159
J9 INT J SURG
JI Int. J. Surg.
PD MAR
PY 2022
VL 99
AR 106250
DI 10.1016/j.ijsu.2022.106250
EA MAR 2022
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 4W9CV
UT WOS:000860453400004
PM 35150922
DA 2026-07-24
ER

PT J
AU Dainty, LA
   Bosco, JJ
   McBroom, JW
   Winter, WE III
   Rose, GS
   Elkas, JC
AF Dainty, LA
   Bosco, JJ
   McBroom, JW
   Winter, WE III
   Rose, GS
   Elkas, JC
TI Novel techniques to improve split-thickness skin graft viability during
   vulvo-vaginal reconstruction
SO GYNECOLOGIC ONCOLOGY
LA English
DT Article
DE fibrin tissue adhesives; split-thickness skin grafts; vulvo-vaginal
   reconstruction; wound vacuum-assisted closure device
ID VACUUM-ASSISTED CLOSURE; FIBRIN GLUE; WOUND FAILURES
AB Background. Split-thickness skin grafts are often utilized for vulvo-vaginal reconstruction. Unfortunately, infection and sloughing may occur in up to 22% of patients with standard techniques especially at irradiated recipient sites.
   Cases. We report seven cases of vulvo-vaginal reconstruction using split-thickness skin grafts. In this series, we used fibrin tissue adhesives with and without vacuum-assisted closure devices to augment graft adherence and viability. We briefly describe the clinical history, surgical techniques, and outcomes of the cohort.
   Conclusion. Fibrin tissue adhesives and wound vacuum-assisted closure devices may improve the viability of split-thickness skin grafts during vulvo-vaginal reconstruction. Published by Elsevier Inc.
C1 Walter Reed Army Med Ctr, Dept Obstet & Gynecol, Div Gynecol Oncol, Washington, DC 20307 USA.
   Tripler Army Med Ctr, Dept Obstet & Gynecol, Div Gynecol Oncol, Honolulu, HI 96859 USA.
   Brooke Army Med Ctr, Dept Obstet & Gynecol, Div Gynecol Oncol, Ft Sam Houston, TX 78234 USA.
C3 Walter Reed National Military Medical Center; United States Department
   of Defense; United States Army; United States Department of Defense;
   United States Army; Tripler Army Medical Center; Brooke Army Medical
   Center; United States Department of Defense; United States Army
RP Elkas, JC (通讯作者)，Walter Reed Army Med Ctr, Dept Obstet & Gynecol, Div Gynecol Oncol, 6900 Georgia Ave NW, Washington, DC 20307 USA.
EM john.elkas@na.amedd.army.mil
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NR 17
TC 20
Z9 26
U1 0
U2 2
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0090-8258
EI 1095-6859
J9 GYNECOL ONCOL
JI Gynecol. Oncol.
PD JUN
PY 2005
VL 97
IS 3
BP 949
EP 952
DI 10.1016/j.ygyno.2005.03.021
PG 4
WC Oncology; Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Obstetrics & Gynecology
GA 937TJ
UT WOS:000229948200037
PM 15896830
DA 2026-07-24
ER

PT J
AU Wang, YL
   Liu, B
   Pi, YZ
   Hu, L
   Yuan, YL
   Luo, J
   Tao, YX
   Li, P
   Lu, S
   Song, W
AF Wang, Yanling
   Liu, Bang
   Pi, Yinzhen
   Hu, Li
   Yuan, Yeling
   Luo, Jiao
   Tao, Yixiao
   Li, Ping
   Lu, Shan
   Song, Wei
TI Risk factors for diabetic foot ulcers mortality and novel negative
   pressure combined with platelet-rich plasma therapy in the treatment of
   diabetic foot ulcers
SO FRONTIERS IN PHARMACOLOGY
LA English
DT Article
DE diabetic foot ulcers (DFUs); diabetic patients without foot ulceration
   (NFU); negative pressure wound therapy (NPWT); platelet-rich
   plasma-fibrin glue (PRP); mortality
ID WOUND THERAPY; RECURRENCE
AB The purpose of this study was to assess the risk factors for morbidity and mortality of diabetic foot ulcers (DFUs). For the treatment of diabetic foot ulcers, negative pressure wound therapy (NPWT) combined with platelet-rich plasma-fibrin glue (PRP) was also investigated. There were 653 patients in the diabetic foot ulcer group and 510 patients in the diabetic patients without foot ulceration (NFU) group, for a total of 1163 patients in the study samples after individuals without follow-up were excluded. The patients were randomized into two groups: the negative pressure wound therapy group and the negative pressure wound therapy combined with the PRP group. The findings of the univariate analysis revealed the blood indicators for predicting diabetic foot ulcer morbidity risk factors, such as C-reactive protein, albumin, creatinine, alkaline phosphatase, procalcitonin, platelets, 25-hydroxyvitamin D, beta-2-microglobulin, monocyte ratio, low-density protein cholesterol (LDL), triglyceride, alanine aminotransferase (ALT), aminotransferase (AST), creatine kinase (CK) and total cholesterol. Using logistic regression analysis revealed only albumin and age to be independent predictors of diabetic foot ulcer mortality. Our study also revealed that, compared to negative pressure wound therapy alone, negative pressure wound therapy combined with PRP accelerated wound healing and reduced the mortality rate. According to the findings of this pilot study, new risk factors for diabetic foot ulcer morbidity and mortality have been found, and negative pressure wound therapy combined with PRP therapy may provide the first information that it is an effective adjunct treatment for diabetic foot ulcers.
C1 [Wang, Yanling; Liu, Bang; Luo, Jiao; Tao, Yixiao; Li, Ping; Lu, Shan] Hunan Normal Univ, Changsha Maternal & Child Hlth Hosp, Changsha, Peoples R China.
   [Pi, Yinzhen; Hu, Li] First Hosp Changsha, Changsha, Peoples R China.
   [Yuan, Yeling] Sun Yat sen Univ, Affiliated Hosp 7, Dept Pediat, Shenzhen, Peoples R China.
   [Song, Wei] Hubei Univ, Coll Hlth Sci & Engn, Natl & Local Joint Engn Res Ctr High Throughput Dr, Wuhan, Peoples R China.
C3 Hunan Normal University; Sun Yat Sen University; Hubei University
RP Song, W (通讯作者)，Hubei Univ, Coll Hlth Sci & Engn, Natl & Local Joint Engn Res Ctr High Throughput Dr, Wuhan, Peoples R China.
EM songwei_83@hubu.edu.cn
RI /A-2615-2013
FU National Natural Science Foundation of China; Changsha Municipal Natural
   Science Foundation [81903484]; Bureau of Public Health of Hunan Province
   [kq2014002]; Open Project Funding of National & Local Joint Engineering
   Research Center of High-throughput Drug Screening Technology
   [202103060456];  [M20202006];  [K20202001]
FX The study was supported by the National Natural Science Foundation of
   China (No. 81903484), the Changsha Municipal Natural Science Foundation
   (kq2014002), the Bureau of Public Health of Hunan Province
   (202103060456), and the Open Project Funding (M20202006 and K20202001)
   of National & Local Joint Engineering Research Center of High-throughput
   Drug Screening Technology.
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NR 24
TC 10
Z9 16
U1 0
U2 29
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
EI 1663-9812
J9 FRONT PHARMACOL
JI Front. Pharmacol.
PD DEC 16
PY 2022
VL 13
AR 1051299
DI 10.3389/fphar.2022.1051299
PG 11
WC Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pharmacology & Pharmacy
GA 7L5BT
UT WOS:000905981700001
PM 36588684
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Wang, T
   Li, X
   Fan, LH
   Chen, B
   Liu, JJ
   Tao, Y
   Wang, XJ
AF Wang, Tao
   Li, Xu
   Fan, Longhua
   Chen, Bin
   Liu, Jianjun
   Tao, Yue
   Wang, Xiaojun
TI Negative pressure wound therapy promoted wound healing by suppressing
   inflammation via down-regulating MAPK-JNK signaling pathway in diabetic
   foot patients
SO DIABETES RESEARCH AND CLINICAL PRACTICE
LA English
DT Article
DE Negative pressure wound therapy; JNK; Diabetic patients; Inflammation
ID NITRIC-OXIDE; TNF-ALPHA; MULTICENTER; MECHANISMS; ULCERS
AB Aims: Negative pressure wound therapy displayed significant clinical benefits in the healing of diabetic foot wounds. In the present study, we investigated the mechanism of regulation of MAPK-JNK (Mitogen-activated protein kinase-c-Jun N-terminal kinase) signaling pathway by negative pressure wound therapy on these wounds.
   Methods: Twenty-six type 2 diabetes patients with foot ulceration were randomly assigned to the two groups, thirteen treated with negative pressure wound therapy and the others treated with traditional debridement therapy. Skin samples were harvested and histologically and immunohistochemical analyzed in both groups. Immunofluorescence stain, Enzyme-linked immunosorbent assay and Western blotting were performed for inducible nitric oxide synthase, inter leukin-6, tumor necrosis factor-alpha, P-c-Jun N-terminal kinase and c-Jun N-terminal kinase. Real time-polymerase chain reaction was performed to evaluate expression of c-Jun N-terminal kinase, extracellular signal regulated kinase1/2 and p38.
   Results: Negative pressure wound therapy could effectively alleviate inflammatory reaction and reduce inter leukin-6 and inducible nitric oxide synthase production after 7 days treatment. The level of tumor necrosis factor-alpha, inter leukin-6 and P-c-Jun N-terminal kinase were significantly decreased. However, there was no statistical difference in messenger ribonucleic acid expression of p38, extracellular signal regulated kinase1 and 2.
   Conclusions: Negative pressure wound therapy possibly suppress the wound inflammation by inhibiting inter leukin-6, tumor necrosis factor-alpha and inducible nitric oxide synthase in diabetic foot patients. This effect is maybe mediated at least in part by suppression of Mitogen-activated protein kinase-c-Jun N-terminal kinase signaling pathway. (C) 2019 Elsevier B.V. All rights reserved.
C1 [Wang, Tao; Li, Xu; Fan, Longhua; Liu, Jianjun; Tao, Yue; Wang, Xiaojun] Fudan Univ, Inst Vasc Surg, QingPu Branch, Zhongshan Hosp,Dept Vasc Surg, Shanghai, Peoples R China.
   [Chen, Bin] Fudan Univ, Zhongshan Hosp, Dept Vasc Surg, Inst Vasc Surg, Shanghai 200032, Peoples R China.
C3 Fudan University; Fudan University
RP Fan, LH (通讯作者)，1158 Pk East, Shanghai 201700, Peoples R China.
EM fanlonghua@163.com
RI Chen, Bin/JVZ-3375-2024; Liu, Jianjun/AAK-4989-2020
FU Shanghai Science and Technology Commission Basic Research Surface Item
   [17ZR1405600]; Health and Family Planning Commission of Qingpu District
   [W2018-18]
FX Thank you very much for your reminding. This study received funding of
   Shanghai Science and Technology Commission Basic Research Surface Item
   (17ZR1405600) and Health and Family Planning Commission of Qingpu
   District (W2018-18).
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NR 29
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U1 0
U2 22
PU ELSEVIER IRELAND LTD
PI CLARE
PA ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000,
   IRELAND
SN 0168-8227
EI 1872-8227
J9 DIABETES RES CLIN PR
JI Diabetes Res. Clin. Pract.
PD APR
PY 2019
VL 150
BP 81
EP 89
DI 10.1016/j.diabres.2019.02.024
PG 9
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA HX8XB
UT WOS:000467689500010
PM 30825563
DA 2026-07-24
ER

PT J
AU Jiang, X
   Bu, FY
   Xu, Y
   Jing, ZH
   Jiao, GQ
   Li, MQ
   Rong, XS
AF Jiang, Xia
   Bu, Fanyu
   Xu, Yong
   Jing, Zhaohui
   Jiao, Guoqing
   Li, Mingqiu
   Rong, Xiaosong
TI Antibiotic-loaded bone cement combined with vacuum sealing drainage to
   treat deep sternal wound infection following cardiac surgery: the first
   case report
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
DE Antibiotic-loaded bone cement; Vacuum sealing drainage; Deep sternal
   wound infection
ID MEDIAN STERNOTOMY; RISK-FACTORS
AB Background Deep sternal wound infection (DSWI) is a rare but serious complication after median sternotomy, and treatment success depends mainly on surgical experience. Here we first present a case of a patient successfully treated for antibiotic-loaded bone cement (ALBC) combined with vacuum sealing drainage (VSD) of DSWI. Case presentation This case report presented a patient who underwent open heart surgery, and suffered postoperatively from a DSWI associated with enterococcus cloacae. Focus debridement combined with ALBC filling and VSD was conducted in stage I. Appropriate antibiotics were started according to sensitivity to be continued for 2 weeks until the inflammatory markers decreased to normal. One month after the surgery, patient's wound was almost healed and was discharged from hospital with a drainage tube. Two months after the stage I surgery procedure, the major step was removing the previous ALBC, and extensive debridement in stage II. The patient fully recovered without further surgical treatment. Conclusions The results of this case suggest that ALBC combined with VSD may be a viable and safe option for deep sternal wound reconstruction.
C1 [Jiang, Xia; Xu, Yong; Jing, Zhaohui; Jiao, Guoqing; Li, Mingqiu; Rong, Xiaosong] Nanjing Med Univ, Wuxi Affiliated Hosp, Wuxi Peoples Hosp, Dept Cardiovasc Surg, Wuxi 214203, Jiangsu, Peoples R China.
   [Bu, Fanyu] Soochow Univ, Dept Chron Wound, Wuxi Peoples Hosp 9, Wuxi 214062, Jiangsu, Peoples R China.
C3 Jiangnan University; Nanjing Medical University; Soochow University -
   China
RP Li, MQ; Rong, XS (通讯作者)，Nanjing Med Univ, Wuxi Affiliated Hosp, Wuxi Peoples Hosp, Dept Cardiovasc Surg, Wuxi 214203, Jiangsu, Peoples R China.
EM LMQ.2109@163.com; rxswx@163.com
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NR 18
TC 2
Z9 3
U1 0
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD OCT 10
PY 2021
VL 16
IS 1
AR 292
DI 10.1186/s13019-021-01673-x
PG 5
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA WE1JT
UT WOS:000705384700005
PM 34629078
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Liu, L
   Tan, G
   Luan, FJ
   Tang, X
   Kang, PD
   Tu, CQ
   Pei, FX
AF Liu, Lei
   Tan, Gang
   Luan, Fujun
   Tang, Xin
   Kang, Pengde
   Tu, Chongqi
   Pei, Fuxing
TI The use of external fixation combined with vacuum sealing drainage to
   treat open comminuted fractures of tibia in the Wenchuan earthquake
SO INTERNATIONAL ORTHOPAEDICS
LA English
DT Article
ID PLATEAU FRACTURES; INTERNAL-FIXATION; ASSISTED CLOSURE; MANAGEMENT;
   CLASSIFICATION; INFECTIONS; PRESSURE; SYSTEM
AB The purpose of this study was to review the results of external fixation combined with vacuum sealing drainage (VSD) to treat patients who sustained tibial and fibular fractures in the Wenchuan earthquake.
   We retrospectively analysed 179 cases (of which 85 were classified as Gustilo grade III) of open comminuted fracture of the tibia and fibula caused by the Wenchuan earthquake. The patients were followed up for an average of 15 months; detailed records were kept on their function and recovery.
   After caring for the life-threatening injuries; fractures were treated by external fixation, with VSD used on the surface or in the cavity of the wound after debridement. Antibiotics were administered on the basis of drug sensitivity test results. After the infection had been controlled and healthy granulation tissue had developed, the patients underwent secondary suture, free skin grafting, or skin flap transfer.
   Good results can be achieved when external fixation combined with vacuum sealing drainage were used to treat open comminuted fractures of tibia and fibula in the Wenchuan earthquake.
C1 [Liu, Lei; Tan, Gang; Luan, Fujun; Tang, Xin; Kang, Pengde; Tu, Chongqi; Pei, Fuxing] Sichuan Univ, W China Hosp, Dept Orthoped, Chengdu 610041, Peoples R China.
C3 Sichuan University
RP Pei, FX (通讯作者)，Sichuan Univ, W China Hosp, Dept Orthoped, Chengdu 610041, Peoples R China.
EM gukeliulei@126.com; peifuxing@vip.163.com
OI Changchao, Dong/0000-0002-5833-4017
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NR 26
TC 23
Z9 42
U1 0
U2 15
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0341-2695
EI 1432-5195
J9 INT ORTHOP
JI Int. Orthop.
PD JUL
PY 2012
VL 36
IS 7
BP 1441
EP 1447
DI 10.1007/s00264-011-1404-6
PG 7
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 963EG
UT WOS:000305602300018
PM 22083371
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Li, SQ
   Guan, XF
   Huang, XR
   Wang, Z
   Mo, LJ
   Xie, MY
   Liu, YX
   Luo, WX
AF Li, Siqing
   Guan, Xiaofang
   Huang, Xirong
   Wang, Zhong
   Mo, Linjie
   Xie, Minyi
   Liu, Yuxia
   Luo, Wenxin
TI Negative pressure wound therapy for preventing wound complications
   following stoma reversal: A systematic review and meta-analysis of
   randomized controlled trials
SO ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
LA English
DT Review
DE Wound complications; Negative pressure wound therapy; Stoma reversal;
   Meta-analysis; Surgical site infections
ID SURGICAL SITE INFECTION; CLOSURE
AB Objective: To evaluate the effectiveness of negative pressure wound therapy in preventing wound complications following colorectal stoma reversal and provide evidence-based recommendations for its clinical application. Methods: A comprehensive search was conducted across five English databases (PubMed, Embase, Web of Science, Cochrane Library, Scopus) and three Chinese databases (Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang) from their inception to December 2024. Grey literature and trial registries were also included. Eligible studies were randomized controlled trials investigating negative pressure wound therapy for patients undergoing stoma reversal. Primary outcomes included wound complications (surgical site infections, hematoma, seroma); secondary outcomes comprised hospital stay, wound healing duration, and dressing costs. Results: Eight randomized trials involving 517 patients were included. Negative pressure wound therapy significantly reduced wound complications (odds ratio, 0.50; 95% confidence interval, 0.27-0.94), shortened wound healing time (mean difference, -4.31; 95% confidence interval, -4.97 to -3.65), and decreased hospital stay (mean difference, -1.05; 95% confidence interval, -1.70 to -0.41). Subgroup analysis demonstrated benefits in the linear closure group (odds ratio, 0.11; 95% confidence interval, 0.02-0.49) but not in the pursestring closure groups. No significant differences were observed in surgical site infections, hematoma, seroma, or dressing costs. Conclusions: Negative pressure wound therapy reduces wound complications, accelerates wound healing, and shortens hospital stays after stoma reversal. Standardized protocols and additional high-quality trials are required to establish negative pressure wound therapy as a routine practice. Systematic review registration: Prospectively registered in PROSPERO (ID CRD42023451001).
C1 [Li, Siqing; Guan, Xiaofang; Huang, Xirong; Mo, Linjie; Liu, Yuxia; Luo, Wenxin] Sun Yat Sen Univ, Affiliated Hosp 5, Dept Gastrointestinal Surg, Zhuhai, Peoples R China.
   [Wang, Zhong] Shenzhen Futian Dist Matern & Child Healthcare Hos, Nursing Dept, Shenzhen, Peoples R China.
   [Xie, Minyi] Sun Yat Sen Univ, Affiliated Hosp 5, Dept Gen Surg, Zhuhai, Peoples R China.
C3 Sun Yat Sen University; Sun Yat Sen University
RP Liu, YX; Luo, WX (通讯作者)，Sun Yat Sen Univ, Affiliated Hosp 5, Dept Gastrointestinal Surg, Zhuhai, Peoples R China.
EM liuyuxia@mail.sysu.edu.cn; luort@mail.sysu.edu.cn
FU Social Development Program of the Zhuhai Science and Technology Bureau
   [2320004000239, 2320004000209]
FX Funding This study was supported by the Social Development
   Program of the Zhuhai Science and Technology Bureau (Grant No.
   2320004000239 and 2320004000209) . The funders had no role in
   considering the study design or in the collection, analysis,
   interpretation of data, writing of the report, or decision to submit the
   article for publication.
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   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Sun Z, 2021, GASTROENT RES PRACT, V2021, DOI 10.1155/2021/5592721
   Tiang T, 2024, ANZ J SURG, V94, P1627, DOI 10.1111/ans.18941
   Uchino M, 2016, DIGEST SURG, V33, P449, DOI 10.1159/000446550
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   Wu Y B, 2019, Zhonghua Wei Chang Wai Ke Za Zhi, V22, P1188, DOI 10.3760/cma.j.issn.1671-0274.2019.12.016
   Xia CY, 2014, MOL MED REP, V9, P1749, DOI 10.3892/mmr.2014.1997
   Xu DY, 2024, WORLD J GASTRO SURG, V16, DOI 10.4240/wjgs.v16.i1.186
   Yane Y, 2021, BMC SURG, V21, DOI 10.1186/s12893-021-01109-2
   Zhu JJ, 2023, J INVEST SURG, V36, DOI 10.1080/08941939.2023.2175079
   Zhu YB, 2022, UPDATES SURG, V74, P1675, DOI 10.1007/s13304-022-01335-0
NR 39
TC 1
Z9 1
U1 2
U2 4
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 2347-5625
EI 2349-6673
J9 ASIA-PAC J ONCOL NUR
JI Asia-Pac. J. Oncol. Nurs.
PD DEC
PY 2025
VL 12
AR 100778
DI 10.1016/j.apjon.2025.100778
EA DEC 2025
PG 10
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 9HJ1D
UT WOS:001606385000003
PM 41210318
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Xu, J
   Wang, QY
   Li, W
AF Xu, Jie
   Wang, Qiao-Yun
   Li, Wei
TI Autologous platelet-rich gel and continuous vacuum sealing drainage for
   the treatment of patients with diabetic foot ulcer Study Protocol
SO MEDICINE
LA English
DT Review
DE autologous platelet-rich gel; continuous vacuum sealing drainage;
   diabetic foot ulcer; efficacy; safety
ID PLASMA GEL; MANAGEMENT
AB Background: Research focusing on the efficacy of autologous platelet-rich gel (APRG) and continuous vacuum sealing drainage (CVSD) for diabetic foot ulcer (DFU) is increasing. Despite increasing knowledge on this theme, its results remain inconsistent. Thus, we will provide insight into the efficacy of APRG and CVSD for patients with DFU.
   Methods: We will search electronic databases of MEDILINE, EMBASE, Cochrane Library, CINAHL, AMED, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure from inception to October 1, 2019. No language limitation is utilized to these databases. Two authors will independently perform study selection, data extraction, and risk of bias assessment. Disagreements between 2 authors will be solved through discussion with a third author.
   Results: The efficacy and safety of APRG and CVSD for patients with DFU will be assessed by the time to complete healing, proportion of ulcers healed within trial period, change of size of ulcer, health-related quality of life, patient length of hospital stay, and adverse events.
   Conclusion: The results of this study will provide helpful evidence of APRG and CVSD for patients with DFU.
C1 [Xu, Jie; Li, Wei] Yanan Univ Affiliated Hosp, Dept Endocrine & Metab, 43 Beida St, Yanan 716000, Shaanxi, Peoples R China.
   [Wang, Qiao-Yun] Yanan Univ Affiliated Hosp, Dept Ultrasound Diag, Yanan, Peoples R China.
C3 Yanan University; Yanan University
RP Li, W (通讯作者)，Yanan Univ Affiliated Hosp, Dept Endocrine & Metab, 43 Beida St, Yanan 716000, Shaanxi, Peoples R China.
EM weill3328@outlook.com
FU Yan'an Science and Technology Huimin Project [2016-HM-08-01]
FX This study is supported by the Yan'an Science and Technology Huimin
   Project (2016-HM-08-01). The funder did not involve any parts of this
   study.
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NR 26
TC 11
Z9 13
U1 0
U2 18
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD NOV
PY 2019
VL 98
IS 46
AR e17928
DI 10.1097/MD.0000000000017928
PG 3
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA JS3YH
UT WOS:000500243900047
PM 31725645
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Peterson, AT
   Bakaysa, SL
   Driscoll, JM
   Kalyanaraman, R
   House, MD
AF Peterson, Ashley T.
   Bakaysa, Stephanie L.
   Driscoll, Janelle M.
   Kalyanaraman, Rajeshwari
   House, Michael D.
TI Randomized controlled trial of single-use negative-pressure wound
   therapy dressings in morbidly obese patients undergoing cesarean
   delivery
SO AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
LA English
DT Article
DE cesarean; negative-pressure wound therapy; obesity; wound complications
ID SURGICAL-SITE INFECTION; RISK; COMPLICATIONS; WOMEN; PREVENTION
AB BACKGROUND: The single-use negative-pressure wound therapy dressings are designed to use over a closed surgical wound. Early prospective studies suggested that these dressings may be of potential benefit in reducing cesarean wound complications.
   OBJECTIVE: This study aimed to test the hypothesis that incisional negative-pressure wound therapy decreases postoperative wound morbidity compared with standard surgical dressing in patients with class III obesity undergoing cesarean delivery.
   STUDY DESIGN: In a single-site, parallel, randomized controlled trial, participants with class III obesity (body mass index >= 40 kg/m(2)) were recruited to participate in the study. Patients were consented in the ambulatory obstetrical units, on admission to the antepartum service, and on labor and delivery before active labor. Patients who had a cesarean delivery were randomized to either the standard surgical dressing or a prophylactic negative-pressure wound therapy device. The randomization was achieved using permuted blocks of 4, 6, and 8 in a 1:1 allocation ratio. The primary outcome was a composite outcome of wound complications. The planned enrollment of 242 subjects was based on the power to detect a 50% decrease in the composite wound outcome, assuming a 30% baseline wound morbidity rate for this population. The outcomes were assessed by study staff blinded to the patient's treatment arm.
   RESULTS: An unplanned interim analysis was performed because of the slow enrollment and publication of larger trials showing no benefit of the negative-pressure wound therapy. Of 411 eligible patients during the study period, 212 participants with class III obesity were enrolled. Of these, 110 underwent cesarean delivery and were subsequently randomized (55 to standard dressing and 55 to prophylactic negative-pressure wound therapy device). The primary outcome occurred in 29.1% in the standard surgical dressing compared with 20% in the negative-pressure wound therapy group (risk difference, 9.1%; 95% confidence interval, -8.3 to 25.8%; P=.38). The study was stopped early because of a low enrollment rate and lower likelihood of seeing a clinically significant benefit.
   CONCLUSION: The trial was stopped after an unplanned, interim analysis showed the use of a prophylactic negative-pressure wound therapy device used for cesarean delivery did not reduce wound complications compared with a standard surgical dressing.
C1 [Peterson, Ashley T.; Bakaysa, Stephanie L.; House, Michael D.] Tufts Med Ctr, Dept Obstet & Gynecol, Div Maternal Fetal Med, Boston, MA 02111 USA.
   [Driscoll, Janelle M.; Kalyanaraman, Rajeshwari] Tufts Med Ctr, Dept Obstet & Gynecol, Boston, MA 02111 USA.
   [House, Michael D.] Tufts Med Ctr, Mother Infant Res Inst, Boston, MA 02111 USA.
   [Bakaysa, Stephanie L.] Hartford Hosp, Div Maternal Fetal Med, Dept Obstet & Gynecol, Hartford, CT 06115 USA.
   [Kalyanaraman, Rajeshwari] St Francis Hosp & Med Ctr, Dept Obstet & Gynecol, Hartford, CT USA.
C3 Tufts Medical Center; Tufts Medical Center; Tufts Medical Center;
   Hartford Hospital; Saint Francis Hospital & Medical Center
RP Peterson, AT (通讯作者)，Tufts Med Ctr, Dept Obstet & Gynecol, Div Maternal Fetal Med, Boston, MA 02111 USA.
EM apeterson@tuftsmedicalcenter.org
RI /AAC-3371-2020; House, Michael/HPH-2039-2023
OI House, Michael/0000-0002-4274-5786; Peterson, Ashley/0000-0002-3971-4567
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NR 25
TC 10
Z9 11
U1 0
U2 4
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29a, 1043 NX AMSTERDAM, NETHERLANDS
SN 2589-9333
J9 AM J OBST GYNEC MFM
JI Amer. J. Obstet. Gynecol. MFM
PD SEP
PY 2021
VL 3
IS 5
AR 100410
DI 10.1016/j.ajogmf.2021.100410
EA JUL 2021
PG 8
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA WM7BK
UT WOS:000711236400037
PM 34058423
DA 2026-07-24
ER

PT J
AU Isoherranen, K
   Kluger, N
   Hannula-Jouppi, K
   Väkevä, L
AF Isoherranen, Kirsi
   Kluger, Nicolas
   Hannula-Jouppi, Katariina
   Vakeva, Liisa
TI The Role of Negative Pressure Wound Therapy (NPWT) in the Management of
   Vasculitic Wounds: Case Series of Eight Patients
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE Inflammatory ulcer; atypical ulcer; cutaneous vasculitis; negative
   pressure wound therapy
ID HIDRADENITIS SUPPURATIVA; CLOSURE
AB Vasculitic ulcers belong to the category of atypical ulcers and are traditionally very slow to heal. The aim of this study is to retrospectively analyze the files of eight patients with vasculitic ulcers treated with negative pressure wound therapy (NPWT). Immunosuppression was initiated at least two weeks prior to starting NPWT. We suggest that this is a safe and promising protocol to treat these hard-to-heal ulcers.
C1 Univ Helsinki, Dept Dermatol & Allergol, Helsinki, Finland.
   Helsinki Univ Hosp, Inflammat Ctr, Helsinki, Finland.
C3 University of Helsinki; University of Helsinki; Helsinki University
   Central Hospital
RP Isoherranen, K (通讯作者)，Univ Helsinki, Cent Hosp, Skin & Allergy Hosp, Meilandentie 2, Helsinki 00250, Finland.
EM kirsi.isoherranen@hus.fi
OI Kluger, Nicolas/0000-0002-5225-8316; Isoherranen,
   Kirsi/0000-0002-0253-2567
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
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NR 24
TC 3
Z9 3
U1 0
U2 3
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD SEP
PY 2024
VL 23
IS 3
BP 445
EP 449
AR 15347346211063700
DI 10.1177/15347346211063700
EA DEC 2021
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA N9B6T
UT WOS:000729521900001
PM 34878340
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Cifuentes, MP
AF Pacheco Cifuentes, Marcela
TI Use of collagen and negative pressure wound therapy in a diabetic foot
   ulcer: a case study
SO JOURNAL OF WOUND CARE
LA Spanish
DT Article
DE diabetic foot; ulcer; negative pressure wound therapy; collagen;
   diabetes
AB SINOPSIS: The following case study describes the use of a collagen layer in combination with negative pressure wound therapy in a diabetic foot ulcer, treated in a hospital in Chile. The wound reduced 58% in size in the first 10 weeks of treatment, reaching complete healing in the following 14 weeks. The treatment carried out avoided amputation of the foot of the patient who, at 64 years of age, maintained his independence and quality of life.
C1 [Pacheco Cifuentes, Marcela] Univ Chile, Hosp Clin, Unidad Procedimientos, Ctr Consultas & Procedimientos, Santiago, Chile.
C3 Universidad de Chile
RP Cifuentes, MP (通讯作者)，Univ Chile, Hosp Clin, Unidad Procedimientos, Ctr Consultas & Procedimientos, Santiago, Chile.
EM mpachecoc@hcuch.cl
CR [Anonymous], 2019, Atlas de la Diabetes de la FID
   Seguel G, 2013, REV MED CHILE, V141, P1464, DOI 10.4067/S0034-98872013001100014
NR 2
TC 1
Z9 1
U1 0
U2 10
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD AUG
PY 2021
VL 30
IS 4
SU 1
BP 19
EP 20
DI 10.12968/jowc.2021.30.LatAm_sup_1.19
PG 2
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA UY2VU
UT WOS:000701387700003
PM 34558975
DA 2026-07-24
ER

PT J
AU Kawata, M
   Nishimura, T
   Hoshino, Y
   Kinoshita, O
   Hisagi, M
   Ando, M
   Morota, T
   Motomura, N
   Kyo, S
   Ono, M
AF Kawata, Mitsuhiro
   Nishimura, Takashi
   Hoshino, Yasuhiro
   Kinoshita, Osamu
   Hisagi, Motoyuki
   Ando, Masahiko
   Morota, Tetsuro
   Motomura, Noboru
   Kyo, Shunei
   Ono, Minoru
TI Negative pressure wound therapy for left ventricular assist
   device-related mediastinitis: two case reports
SO JOURNAL OF ARTIFICIAL ORGANS
LA English
DT Article
DE Negative pressure wound therapy; Left ventricular assist device;
   Mediastinitis; Quality of life
ID CLOSURE; INFECTIONS; SUPPORT
AB We report two cases of successful use of negative pressure wound therapy (NPWT) to control of left ventricular assist device (LVAD)-related mediastinitis. It is difficult to treat mediastinitis in patients who have undergone LVAD implantation, because it is impossible to remove the infected artificial materials from the mediastinal space. This report indicates that NPWT might become the preferred therapeutic option for control of mediastinitis in patients who have undergone LVAD implantation.
C1 [Kawata, Mitsuhiro; Nishimura, Takashi; Hoshino, Yasuhiro; Kinoshita, Osamu; Hisagi, Motoyuki; Ando, Masahiko; Morota, Tetsuro; Motomura, Noboru; Kyo, Shunei; Ono, Minoru] Univ Tokyo, Dept Cardiothorac Surg, Fac Med, Bunkyo Ku, Tokyo 1138654, Japan.
C3 University of Tokyo
RP Kawata, M (通讯作者)，Univ Tokyo, Dept Cardiothorac Surg, Fac Med, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138654, Japan.
EM mkawata-ths@umin.ac.jp; takashin-tky@umin.ac.jp
RI Motomura, Noboru/AAK-6000-2020
FU Grants-in-Aid for Scientific Research [21249073] Funding Source: KAKEN
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Kinoshita O, 2010, J ARTIF ORGANS, V13, P126, DOI 10.1007/s10047-010-0500-5
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Petzina R, 2010, J THORAC CARDIOV SUR, V140, P1133, DOI 10.1016/j.jtcvs.2010.06.063
   Petzina R, 2010, EUR J CARDIO-THORAC, V38, P110, DOI 10.1016/j.ejcts.2010.01.028
   Sinha P, 2000, CIRCULATION, V102, P194
   Zierer A, 2007, ANN THORAC SURG, V84, P515, DOI 10.1016/j.athoracsur.2007.03.085
NR 8
TC 12
Z9 12
U1 0
U2 0
PU SPRINGER TOKYO
PI TOKYO
PA 1-11-11 KUDAN-KITA, CHIYODA-KU, TOKYO, 102-0073, JAPAN
SN 1434-7229
J9 J ARTIF ORGANS
JI J. Artif. Organs
PD JUN
PY 2011
VL 14
IS 2
BP 159
EP 162
DI 10.1007/s10047-011-0555-y
PG 4
WC Engineering, Biomedical; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Transplantation
GA 778XU
UT WOS:000291743500011
PM 21347682
DA 2026-07-24
ER

PT J
AU Yu, LL
   Kronen, RJ
   Simon, LE
   Stoll, CRT
   Colditz, GA
   Tuuli, MG
AF Yu, Lulu
   Kronen, Ryan J.
   Simon, Laura E.
   Stoll, Carolyn R. T.
   Colditz, Graham A.
   Tuuli, Methodius G.
TI Prophylactic negative-pressure wound therapy after cesarean is
   associated with reduced risk of surgical site infection: a systematic
   review and meta-analysis
SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
LA English
DT Review
DE antibiotics; cesarean delivery; dehiscence; endometritis; hospital
   readmission; meta-analysis; prophylactic negative-pressure wound
   therapy; seroma; surgical site infection
ID OBESE WOMEN; COMPLICATIONS; MANAGEMENT; DELIVERY; SECTION; INCISION;
   TRIAL
AB OBJECTIVE: The objective of the study was to assess the effect of prophylactic negative-pressure wound therapy on surgical site infections and other wound complications in women after cesarean delivery.
   DATA SOURCES: We searched Ovid Medline, Embase, SCOPUS, Cochrane Database of Systematic Reviews, and ClinicalTrials.gov.
   STUDY ELIGIBILITY CRITERIA: We included randomized controlled trials and observational studies comparing prophylactic negative-pressure wound therapy with standard wound dressing for cesarean delivery.
   STUDY APPRAISAL AND SYNTHESIS METHODS: The primary outcome was surgical site infection after cesarean delivery. Secondary outcomes were composite wound complications, wound dehiscence, wound seroma, endometritis, and hospital readmission. Heterogeneity was assessed using Higgin's I-2. Relative risks with 95% confidence intervals were calculated using random-effects models.
   RESULTS: Six randomized controlled trials and 3 cohort studies in high-risk mostly obese women met inclusion criteria and were included in the meta-analysis. Six were full-text articles, 2 published abstracts, and 1 report of trial results in ClinicalTrials. gov. Studies were also heterogeneous in the patients included and type of negative-pressure wound therapy device. The risk of surgical site infection was significantly lower with the use of prophylactic negative-pressure wound therapy compared with standard wound dressing (7 studies: pooled risk ratio, 0.45; 95% confidence interval, 0.31-0.66; adjusted risk ratio, -6.0%, 95% confidence interval, -10.0% to -3.0%; number needed to treat, 17, 95% confidence interval, 10-34). There was no evidence of significant statistical heterogeneity (I-2 = 9.9%) or publication bias (Egger P =.532). Of the secondary outcomes, only composite wound complications were significantly reduced in patients receiving prophylactic negative-pressure wound therapy compared with standard dressing (9 studies: pooled risk ratio, 0.68, 95% confidence interval, 0.49-0.94).
   CONCLUSION: Studies on the effectiveness of prophylactic negative-pressure wound therapy at cesarean delivery are heterogeneous but suggest a reduction in surgical site infection and overall wound complications. Larger definitive trials are needed to clarify the clinical utility of prophylactic negative-pressure wound therapy after cesarean delivery.
C1 [Yu, Lulu; Kronen, Ryan J.; Colditz, Graham A.] Washington Univ, Sch Med, St Louis, MO 63110 USA.
   [Simon, Laura E.] Washington Univ, Sch Med, Becker Med Lib, St Louis, MO USA.
   [Stoll, Carolyn R. T.] Washington Univ, Sch Med, Dept Surg, Div Publ Hlth Sci, St Louis, MO 63110 USA.
   [Colditz, Graham A.] Washington Univ, Sch Med, Inst Publ Hlth, St Louis, MO USA.
   [Tuuli, Methodius G.] Washington Univ, Sch Med, Dept Obstet & Gynecol, Div Maternal Fetal Med, St Louis, MO 63110 USA.
C3 Washington University (WUSTL); Washington University (WUSTL); Washington
   University (WUSTL); Washington University (WUSTL); Washington University
   (WUSTL)
RP Yu, LL (通讯作者)，Washington Univ, Sch Med, St Louis, MO 63110 USA.
EM lulu.yu@wustl.edu
RI Colditz, Graham/A-3963-2009; Simon, Laura/AAN-2353-2021
OI Colditz, Graham/0000-0002-7307-0291; Simon, Laura/0000-0002-3760-6810
FU Foundation for Barnes Jewish Hospital; National Institutes of Health
   [U01HD077384-03, 1R01HD086007-01]; Acelity, manufacturers of Prevena
FX Dr Colditz is supported in part by the Foundation for Barnes Jewish
   Hospital. Dr. Tuuli is supported by National Institutes of Health grants
   U01 (U01HD077384-03) and R01 (1R01HD086007-01). Dr Tuuli received
   supplemental research grant funding from Acelity, manufacturers of
   Prevena.
CR [Anonymous], INNOVATIONS ADV WOUN
   [Anonymous], PROPHYLACTIC INCISIO
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NR 31
TC 66
Z9 73
U1 0
U2 12
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0002-9378
EI 1097-6868
J9 AM J OBSTET GYNECOL
JI Am. J. Obstet. Gynecol.
PD FEB
PY 2018
VL 218
IS 2
BP 200
EP +
DI 10.1016/j.ajog.2017.09.017
PG 12
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA FV4JB
UT WOS:000424538300009
PM 28951263
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Phillips, R
   Stannard, JP
   Crist, BD
AF Phillips, Rachel
   Stannard, James P.
   Crist, Brett D.
TI Incisional Negative Pressure Wound Therapy in Orthopaedic Trauma:
   Indications & Outcomes
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE wound management; incisional negative pressure wound therapy; negative
   pressure; incision management
ID FINANCIAL IMPACT; INFECTIONS
AB The treatment of surgical incisions has evolved. This article aims to discuss the indications and outcomes associated with the use of incisional negative pressure wound therapy (iNPWT) for the management of surgical incisions. Multiple factors play a role in the benefits seen with iNPWT. The primary indication for iNPWT is to help manage the closed surgical incision environment and remove fluid from the incision via application of continuous negative pressure at -125 mm Hg. Pertinent literature will be reviewed.
C1 [Phillips, Rachel; Stannard, James P.; Crist, Brett D.] Univ Missouri, Dept Orthopaed Surg, One Hosp Dr, Columbia, MO 65212 USA.
C3 University of Missouri System; University of Missouri Columbia
RP Crist, BD (通讯作者)，Univ Missouri, Dept Orthopaed Surg, One Hosp Dr, Columbia, MO 65212 USA.
EM cristb@health.missouri.edu
RI Crist, Brett/AAC-7535-2019
CR Abbas SM, 2009, ANZ J SURG, V79, P247, DOI 10.1111/j.1445-2197.2009.04854.x
   Avsar P, 2021, WOUND MANAG PREV, V67, DOI 10.25270/wmp.2021.6.1019
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   Borgquist O, 2010, ANN PLAS SURG, V64, P789, DOI 10.1097/SAP.0b013e3181ba578a
   Cagney D, 2020, WORLD J SURG, V44, P1526, DOI 10.1007/s00268-019-05335-x
   Crist BD, 2017, INJURY, V48, P1518, DOI 10.1016/j.injury.2017.04.055
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   Lin KC, 2020, INJURY, V51, P1805, DOI 10.1016/j.injury.2020.05.032
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   Suh H, 2016, ANN PLAS SURG, V76, P717, DOI 10.1097/SAP.0000000000000231
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NR 23
TC 0
Z9 1
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD SEP
PY 2022
VL 36
SU 4
BP S22
EP S25
DI 10.1097/BOT.0000000000002425
PG 4
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 3Y2NF
UT WOS:000843564400006
PM 35994305
DA 2026-07-24
ER

PT J
AU Cannata, A
   Ordanini, M
   Sesana, G
   Russo, CF
AF Cannata, Aldo
   Ordanini, Marco
   Sesana, Giovanni
   Russo, Claudio Francesco
TI Nonoperative Management of a Recurrent Postoperative Inguinal Lymphatic
   Leak via Negative-Pressure Wound Therapy: A Case Report
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
DE cardiac; femoral vessels; lymphatic leak; negative-pressure wound
   therapy; NPWT; postoperative complication; surgery; vascular
AB Lymphatic leaks are common following common femoral vessel exposure for cardiac surgical procedures. The management of this complication can be difficult and is often uncomfortable for the patient. This case report describes the successful nonoperative treatment of a recurrent lymphatic leak from an inguinal surgical wound via negative-pressure wound therapy. Negative pressure may be considered a minimally invasive, effective, and acceptable way to treat postoperative lymphatic leaks at the groin.
C1 [Cannata, Aldo] Osped Niguarda Ca Granda, Milan, Italy.
   [Ordanini, Marco; Russo, Claudio Francesco] Dept Cardiac Surg, Milan, Italy.
   [Sesana, Giovanni; Russo, Claudio Francesco] Wound Healing Ctr, Cleveland, OH USA.
C3 Ospedale Niguarda Ca' Granda; IRCCS Ca Granda Ospedale Maggiore
   Policlinico
RP Cannata, A (通讯作者)，Osped Niguarda Ca Granda, Milan, Italy.
OI Russo, Claudio Francesco/0000-0001-5439-1420
CR Abai B, 2007, J VASC SURG, V45, P610, DOI 10.1016/j.jvs.2006.10.043
   Andersson S, 2018, ANN VASC SURG, V48, P104, DOI 10.1016/j.avsg.2017.10.018
   Eom Y, 2019, ADV SKIN WOUND CARE, V32, P183, DOI 10.1097/01.ASW.0000553596.11034.d7
   Lamelas J, 2017, ANN THORAC SURG, V103, P1927, DOI 10.1016/j.athoracsur.2016.09.098
   Moschovas A, 2017, INTERACT CARDIOV TH, V25, P377, DOI 10.1093/icvts/ivx140
   Swinnen J, 2010, ANN VASC SURG, V24, P336, DOI 10.1016/j.avsg.2009.07.020
   Tauber R, 2013, J PLAST RECONSTR AES, V66, P390, DOI 10.1016/j.bjps.2012.09.030
   Uhl C, 2020, ANN VASC SURG, V62, P382, DOI 10.1016/j.avsg.2019.06.011
   Van den Brande P, 2012, ANN VASC SURG, V26, P833, DOI 10.1016/j.avsg.2012.02.009
   Yuan Y, 2019, J SURG RES, V235, P329, DOI 10.1016/j.jss.2018.09.065
NR 10
TC 1
Z9 1
U1 1
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD OCT
PY 2021
VL 34
IS 10
DI 10.1097/01.ASW.0000775928.63723.3b
PG 3
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA US3QW
UT WOS:000697349000001
PM 34546209
DA 2026-07-24
ER

PT J
AU Oradan, A
   Muntean, M
AF Oradan, Alex
   Muntean, Maximilian
TI The Use of Negative Pressure Wound Therapy in the Management of Parotid
   Sialocele: A Case Report
SO LARYNGOSCOPE
LA English
DT Article
DE Sialocele; parotid gland; negative pressure wound therapy; sentinel
   lymph node biopsy
AB Parotid sialocele is an accumulation of saliva inside a subcutaneous cavity, usually as a result of trauma or iatrogenic injury of the parotid gland or duct, which can progress to other complications if left untreated. Numerous treatment options have been described before, but there is currently no evidence based consensus. We present a case of a patient treated for sialocele with the use of negative pressure wound therapy.Laryngoscope, 2020
C1 [Oradan, Alex; Muntean, Maximilian] Univ Med & Pharm Iuliu Hatieganu, Dept Plast Surg, Prof Dr I Chiricuta Inst Oncol, Str Republ 34-6, Cluj Napoca 400015, Romania.
C3 Iuliu Hatieganu University of Medicine & Pharmacy; Oncology Institute
   Prof. Dr. Ion Chiricuta
RP Oradan, A (通讯作者)，Univ Med & Pharm Iuliu Hatieganu, Dept Plast Surg, Prof Dr I Chiricuta Inst Oncol, Str Republ 34-6, Cluj Napoca 400015, Romania.
EM alex.oradan@yahoo.com
RI Muntean, Maximilian/HJP-8255-2023; Orădan, Alex/LJL-5044-2024
OI Muntean, Maximilian/0000-0003-0709-8779; Orădan,
   Alex/0000-0001-5911-983X
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Ashkenazi I, 2017, SURG J-NY, V3, DOI 10.1055/s-0037-1599273
   Lee YC, 2016, HEAD NECK-J SCI SPEC, V38, pE941, DOI 10.1002/hed.24130
   Maharaj S, 2020, LARYNGOSCOPE INVEST, V5, P37, DOI 10.1002/lio2.350
   Nagi R, 2016, J DIAGN RES, V10, P4
NR 5
TC 2
Z9 3
U1 1
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0023-852X
EI 1531-4995
J9 LARYNGOSCOPE
JI Laryngoscope
PD APR
PY 2021
VL 131
IS 4
BP E1094
EP E1095
DI 10.1002/lary.29078
EA SEP 2020
PG 2
WC Medicine, Research & Experimental; Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Otorhinolaryngology
GA QU0KJ
UT WOS:000566834300001
PM 32898314
DA 2026-07-24
ER

PT J
AU Franczyk, M
   Lohman, RF
   Agarwal, JP
   Rupani, G
   Drum, M
   Gottlieb, LJ
AF Franczyk, Mieczyslawa
   Lohman, Robert F.
   Agarwal, Jayant P.
   Rupani, Gita
   Drum, Melinda
   Gottlieb, Lawrence J.
TI The Impact of Topical Lidocaine on Pain Level Assessment during and
   after Vacuum-Assisted Closure Dressing Changes: A Double-Blind,
   Prospective, Randomized Study
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID LOCAL-ANESTHESIA; MANAGEMENT; LACERATIONS; NO
AB Background: Vacuum-assisted closure dressing changes are frequently painful. The authors hypothesized that administering topical lidocaine into the vacuum-assisted closure sponge would decrease pain during dressing changes.
   Methods: A double-blind, randomized, prospective study was performed on patients (n = 70) undergoing vacuum-assisted closure dressing changes at a single institution between October of 2003 and June of 2005. Patients were randomized to receive either 0.2% lidocaine or 0.9% saline administered through the vacuum-assisted closure tubing into the foam dressing 30 minutes before changing the dressing. All patients received morphine sulfate ad libitum. Pain scores were assessed according to a 0 to 10 numeric pain scale.
   Results: Wound characteristics and patient demographics were similar for both groups. Patients receiving lidocaine reported less pain than control patients during the dressing change (4.3 versus 6.3; p = 0.005) and immediately after (2.4 versus 4.7; p < 0.001) the dressing change. Thirty minutes after the dressing change, pain scores were similar in both groups. Thirty minutes after the dressing change, more patients in the lidocaine group requested small doses of narcotics (> 3 mg morphine equivalent) than in the control group.
   Conclusions: During the initial vacuum-assisted closure dressing change, 0.2% lidocaine administered through the suction tubing led to a reduction in pain reported by the patients in the authors' study. The duration of lidocaine administered in this fashion may be fairly short, because more patients in this group began to request small doses of opiates 30 minutes after the dressing change. Thus, lidocaine may improve patient comfort during vacuum-assisted closure therapy. (Plast. Reconstr. Surg. 124: 854, 2009.)
C1 [Lohman, Robert F.] Cleveland Clin Fdn, Dept Plast Surg, Cleveland, OH 44195 USA.
   Univ Chicago, Med Ctr, Dept Therapy Serv, Chicago, IL 60637 USA.
   Univ Chicago, Med Ctr, Dept Anesthesiol & Crit Care, Chicago, IL 60637 USA.
   Univ Chicago, Med Ctr, Sect Plast Surg, Chicago, IL 60637 USA.
   Univ Utah, Div Plast Surg, Salt Lake City, UT USA.
   Univ Chicago, Dept Hlth Studies, Chicago, IL 60637 USA.
C3 Cleveland Clinic Foundation; University of Chicago; University of
   Chicago Medical Center; University of Chicago; University of Chicago
   Medical Center; University of Chicago; University of Chicago Medical
   Center; Utah System of Higher Education; University of Utah; University
   of Chicago
RP Lohman, RF (通讯作者)，Cleveland Clin Fdn, Dept Plast Surg, Desk A-60,9500 Euclid Ave, Cleveland, OH 44195 USA.
EM lohmanr@ccf.org
CR BUTTERWORTH JF, 1990, ANESTHESIOLOGY, V72, P711, DOI 10.1097/00000542-199004000-00022
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   Strichrtz GR., 2005, MILLERS ANAESTHESIA, V6th Edn, P573
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NR 28
TC 31
Z9 35
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD SEP
PY 2009
VL 124
IS 3
BP 854
EP 861
DI 10.1097/PRS.0b013e3181b038b4
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 490FT
UT WOS:000269485200019
PM 19730304
DA 2026-07-24
ER

PT J
AU Younan, G
   Ogawa, R
   Ramirez, M
   Helm, D
   Dastouri, P
   Orgill, DP
AF Younan, George
   Ogawa, Rei
   Ramirez, Michelle
   Helm, Douglas
   Dastouri, Pouya
   Orgill, Dennis P.
TI Analysis of Nerve and Neuropeptide Patterns in Vacuum-Assisted
   Closure-Treated Diabetic Murine Wounds
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID GROWTH-FACTOR; PRESSURE ULCERS; SKIN; INFLAMMATION; NEUROPATHY; MICE;
   FOOT; ANGIOGENESIS; TISSUE; SCAR
AB Background: Reestablishment of the peripheral nervous system occurs in parallel with wound healing. With accelerated wound healing seen with the vacuum-assisted closure device, the authors studied its effects on nerve fiber regeneration, nerve sprouting, and the stimulation of neuropeptides and neurotrophins.
   Methods: A vacuum-assisted closure device was applied to a full-thickness diabetic mouse wound using continuous or cyclical modes and compared with foam dressing or occlusive dressing controls, using 10 mice per group. Nerve fibers, substance P, calcitonin gene-related peptide, and nerve growth factor were analyzed using two-dimensional immunohistochemistry and real-time reverse-transcriptase polymerase chain reaction.
   Results: A significant increase in dermal and epidermal nerve fiber densities and in substance P, calcitonin gene-related peptide, and nerve growth factor expression was seen in vacuum-assisted closure treated wounds. Cyclical treatment mode correlated with the largest increase in granulation tissue production, wound surface microdeformations, and a slightly faster wound closure rate.
   Conclusions: This study suggests that vacuum-assisted closure therapy can modulate nerve fiber and neuropeptide production in the wound. Optimized kinetics of vacuum-assisted closure application may provide an opportunity for clinicians to further improve wound healing in denervated wounds such as pressure sores and diabetic foot ulcerations. (Plast. Reconstr. Surg. 126: 87, 2010.)
C1 [Orgill, Dennis P.] Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Plast Surg, Boston, MA 02115 USA.
   Nippon Med Sch, Dept Plast Reconstruct & Aesthet Surg, Tokyo 113, Japan.
C3 Harvard University; Harvard Medical School; Harvard University Medical
   Affiliates; Brigham & Women's Hospital; Nippon Medical School
RP Orgill, DP (通讯作者)，Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
EM dorgill@partners.org
RI Orgill, Dennis/H-7596-2019
OI Orgill, Dennis/0000-0002-8279-7310; Younan, George/0000-0001-8502-4850
FU Kinetic Concepts, Inc., San Antonio, Texas
FX Dr. Orgill is the principal investigator on studies receiving research
   grants to the Brigham and Women's Hospital by Kinetic Concepts, Inc.,
   San Antonio, Texas, and is also an expert witness for Kinetic Concepts,
   Inc. The bioreactor used in this study, suction apparatus, and foam were
   provided by Kinetic Concepts, Inc. The other authors have no financial
   conflicts of interest and do not have any financial or business liaison,
   to Kinetic Concepts, Inc.
CR Akaishi S, 2008, MED HYPOTHESES, V71, P32, DOI 10.1016/j.mehy.2008.01.032
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   Simms M, 2009, J CARDIOVASC SURG, V50, P293
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NR 38
TC 40
Z9 52
U1 0
U2 13
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JUL
PY 2010
VL 126
IS 1
BP 87
EP 96
DI 10.1097/PRS.0b013e3181da86d0
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 614ZD
UT WOS:000279097500011
PM 20595860
DA 2026-07-24
ER

PT J
AU Elce, YA
   Ruzickova, P
   da Silveira, EA
   Laverty, S
AF Elce, Y. A.
   Ruzickova, P.
   da Silveira, E. Almeida
   Laverty, S.
TI Use of negative pressure wound therapy in three horses with open,
   infected olecranon bursitis
SO EQUINE VETERINARY EDUCATION
LA English
DT Article
DE horse; negative pressure wound therapy; olecranon bursitis; infection;
   granulation tissue
AB This article describes the clinical use of negative pressure wound therapy (NPWT) in three horses with an open and infected subcutaneous olecranon bursa, in which prior surgical excision followed by primary closure was unsuccessful. The wounds filled in rapidly with granulation tissue and contracted during therapy. All wounds subsequently went on to heal without complications. The use of NPWT was well tolerated in all three horses and facilitated healing in a difficult area.
C1 [Elce, Y. A.; Ruzickova, P.; da Silveira, E. Almeida; Laverty, S.] Univ Montreal, Equine Hosp, Coll Vet Med, St Hyacinthe, PQ, Canada.
   [Elce, Y. A.] Langford Vets, Equine Hosp, Langford House, Bristol, Avon, England.
C3 Universite de Montreal
RP Elce, YA (通讯作者)，Univ Montreal, Equine Hosp, Coll Vet Med, St Hyacinthe, PQ, Canada.; Elce, YA (通讯作者)，Langford Vets, Equine Hosp, Langford House, Bristol, Avon, England.
EM Yvonne.elce@bristol.ac.uk
RI Elce, Yvonne/AAC-9376-2021
CR Ben-Amotz R, 2007, VET SURG, V36, P684, DOI 10.1111/j.1532-950X.2007.00321.x
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   Ren YH, 2017, INT J BURNS TRAUMA, V7, P12
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NR 22
TC 6
Z9 9
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0957-7734
EI 2042-3292
J9 EQUINE VET EDUC
JI Equine Vet. Educ.
PD JAN
PY 2020
VL 32
IS 1
BP 12
EP 17
DI 10.1111/eve.12930
PG 6
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA QH8NV
UT WOS:000618529900004
DA 2026-07-24
ER

PT J
AU Hirai, Y
   Yamashita, Y
   Tazawa, H
   Suzuki, T
   Fujimoto, S
   Uemura, T
   Mimura, T
AF Hirai, Yuya
   Yamashita, Yoshinori
   Tazawa, Hirofumi
   Suzuki, Takahisa
   Fujimoto, Sari
   Uemura, Takahiro
   Mimura, Takeshi
TI Negative pressure wound therapy for broncho-pleural fistula with
   collapsed lung
SO GENERAL THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
DE Empyema; Broncho-pleural fistula; Negative pressure wound therapy
ID MANAGEMENT
AB We present a case of the broncho-pleural fistula with a collapsed lung that was developed 2 weeks after right lower lobectomy. The patient urgently underwent open-window thoracostomy. However, the residual lung remained collapsed. To expand the lung and close the broncho-pleural fistula, negative pressure wound therapy was initiated 20 days after the procedure. The lung expanded within a few days, and the residual thoracic cavity gradually contracted. Subsequently, 2.5 months later, the remaining thoracic cavity was successfully closed using omentoplasty. No recurrence of the broncho-pleural fistula was observed for 1 year. If the lung could be inflated to reduce dead space in the thoracic cavity, broncho-pleural fistula with collapsed lung may be treated with bronchial stump coverage and negative pressure wound therapy.
C1 [Hirai, Yuya; Yamashita, Yoshinori; Mimura, Takeshi] Natl Hosp Org Kure Med Ctr & Chugoku Canc Ctr, Dept Gen Thorac Surg, 3-1 Aoyama Cho, Hiroshima 7370023, Japan.
   [Tazawa, Hirofumi; Suzuki, Takahisa] Natl Hosp Org Kure Med Ctr & Chugoku Canc Ctr, Dept Surg, 3-1 Aoyama Cho, Hiroshima 7370023, Japan.
   [Fujimoto, Sari; Uemura, Takahiro] Natl Hosp Org Kure Med Ctr & Chugoku Canc Ctr, Dept Plast Surg, 3-1 Aoyama Cho, Hiroshima 7370023, Japan.
RP Mimura, T (通讯作者)，Natl Hosp Org Kure Med Ctr & Chugoku Canc Ctr, Dept Gen Thorac Surg, 3-1 Aoyama Cho, Hiroshima 7370023, Japan.
EM t.mimura88@gmail.com
OI Mimura, Takeshi/0000-0002-2809-4833
CR Aru GM, 2010, ANN THORAC SURG, V90, P266, DOI 10.1016/j.athoracsur.2010.04.092
   ASAMURA H, 1992, J THORAC CARDIOV SUR, V104, P1456
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   Regnard JF, 2000, J THORAC CARDIOV SUR, V120, P270, DOI 10.1067/mtc.2000.106837
   Shen KR, 2017, J THORAC CARDIOV SUR, V153, pE129, DOI 10.1016/j.jtcvs.2017.01.030
NR 5
TC 0
Z9 1
U1 0
U2 2
PU SPRINGER JAPAN KK
PI TOKYO
PA SHIROYAMA TRUST TOWER 5F, 4-3-1 TORANOMON, MINATO-KU, TOKYO, 105-6005,
   JAPAN
SN 1863-6705
EI 1863-6713
J9 GEN THORAC CARDIOVAS
JI Gen. Thorac. Cardiovasc. Surg.
PD MAY
PY 2021
VL 69
IS 5
BP 890
EP 893
DI 10.1007/s11748-020-01569-y
EA JAN 2021
PG 4
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA RP7LS
UT WOS:000605139500005
PM 33400203
DA 2026-07-24
ER

PT J
AU Campbell, PE
   Bonham, PA
AF Campbell, PE
   Bonham, PA
TI Surgical wound case studies with the versatile 1 wound vacuum system for
   negative pressure wound therapy
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
ID ASSISTED CLOSURE; MANAGEMENT; DRESSINGS; ULCERS
AB Negative pressure wound therapy consists of a wound dressing, a drainage tube inserted into the dressing, an occlusive transparent film, and a connection to a vacuum source that supplies the negative pressure. A new product called the Versatile 1 Wound Vacuum System (BlueSky Medical, La Costa, Calif) is available for negative pressure wound therapy. This article describes the application, management, and effectiveness of the Versatile 1 in 3 cases where the patients have all undergone surgical debridement.
C1 Avalon Healthcare, Nashville, TN 37211 USA.
   Med Univ S Carolina, Coll Nursing, Wound Care Educ Program, Charleston, SC USA.
C3 Medical University of South Carolina
RP Campbell, PE (通讯作者)，Avalon Healthcare, 5609 Seesaw Rd, Nashville, TN 37211 USA.
EM campvols@comcast.net
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NR 34
TC 18
Z9 36
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAR-APR
PY 2006
VL 33
IS 2
BP 176
EP 190
DI 10.1097/00152192-200603000-00014
PG 15
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 026LU
UT WOS:000236341200010
PM 16572020
DA 2026-07-24
ER

PT J
AU Ueda, M
   Makoto, O
   Sakai, A
AF Ueda, Misato
   Makoto, Omori
   Sakai, Ayumi
TI Use of a Skin-Covering Pocket as a Local Flap and Negative Pressure
   Wound Therapy with Instillation and Dwell Time/Negative Pressure Wound
   Therapy for the Treatment of Diabetic Foot Ulcer with Calcaneal
   Osteomyelitis
SO JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION
LA English
DT Article
ID RECONSTRUCTION
AB For diabetic foot ulcers with "pockets" (wound edge undermining), a surgical incision to the undermining space and debridement are required primarily. Osteomyelitis should be treated if present. Furthermore, it is necessary for the foot to be able to withstand load after control-ling the infection and necrosis. We report a case of a patient treated with a skin-covering pocket as a local flap and negative pressure wound therapy with instillation and dwell time and negative pressure wound therapy to relieve osteomyelitis and promote wound contraction. There was no involvement of other body parts, and only the pocket consisting of skin at the sole of the foot was used, and load could be withstood.
C1 [Ueda, Misato; Makoto, Omori; Sakai, Ayumi] Yodogawa Christians Hosp, Dept Plast Surg, Osaka, Japan.
   [Ueda, Misato] Yodogawa Christians Hosp, Dept Plast Surg, 1-7-50 Kunijima,Higashiyodogawa Ku,, Osaka 5330024, Japan.
RP Ueda, M (通讯作者)，Yodogawa Christians Hosp, Dept Plast Surg, 1-7-50 Kunijima,Higashiyodogawa Ku,, Osaka 5330024, Japan.
EM sakuramochi0v0@yahoo.co.jp
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   EDGARDO RC, 2017, Clin Surg, V2, P1632
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   Faust E, 2021, PLAST RECONSTR SURG, V147, p16S, DOI 10.1097/PRS.0000000000007607
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NR 14
TC 2
Z9 2
U1 0
U2 0
PU AMER PODIATRIC MED ASSOC
PI BETHESDA
PA 9312 OLD GEORGETOWN ROAD, BETHESDA, MD 20814-1621 USA
SN 8750-7315
EI 1930-8264
J9 J AM PODIAT MED ASSN
JI J. Am. Podiatr. Med. Assoc.
PD SEP-OCT
PY 2023
VL 113
IS 5
AR 061
DI 10.7547/21-061
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA Z4SW7
UT WOS:001112001800014
PM 37938898
DA 2026-07-24
ER

PT J
AU Marathe, US
   Sniezek, JC
AF Marathe, US
   Sniezek, JC
TI Use of the vacuum-assisted closure device in enhancing closure of a
   massive skull defect
SO LARYNGOSCOPE
LA English
DT Article
DE eccrine carcinoma; skull defect; negative-pressure dressing;
   vacuum-assisted closure
ID WOUND CONTROL; MANAGEMENT; SYSTEM
AB Objectives/Hypothesis: The objective was to describe a novel technique for reconstructing the cranial vertex without the use of free tissue transfer. Study Design: Case report, literature review, and discussion. Methods: A 50-year-old woman presented from a remote Pacific Island community with a 12 x 14-cm, necrotic, grossly contaminated eccrine gland carcinoma of the cranial vertex that extended through the calvarium but did not invade the dura. Following tumor extirpation, the resulting bony defect was 10 x 12 cm in size, with a concomitant scalp defect of 14 x 16 em. Free tissue transfer was impossible because of severe intimal peripheral vascular disease, posing a challenging reconstructive dilemma. After tumor resection, the bony edges were covered with local scalp flaps and the vacuum-assisted closure device was placed over the wound at a constant setting of -50 mm Hg. The vacuum-assisted closure device was changed three times per week for 3 weeks. Results: A thick, 1-cm bed of granulation tissue developed over the dura, allowing temporary coverage by a split-thickness skin graft, and the scalp defect decreased in size by approximately 25%. The patient did not develop meningitis, headache, or localized infection as a result of placement of the vacuum-assisted closure device and tolerated the vacuum-assisted closure well. After a requisite period of healing, tissue expanders and calvarial reconstruction will be performed. Conclusion: Use of the vacuum-assisted closure device is a safe, reliable adjunct in the closure of large cranial defects with exposed dura and offers a novel reconstructive option for complex defects of the head and neck.
C1 Tripler Army Med Ctr, Dept Otolaryngol, Honolulu, HI 96859 USA.
C3 United States Department of Defense; United States Army; Tripler Army
   Medical Center
RP Sniezek, JC (通讯作者)，Tripler Army Med Ctr, Dept Otolaryngol, 1 Jarrett White Rd, Honolulu, HI 96859 USA.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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   Josty IC, 2001, BRIT J PLAST SURG, V54, P363, DOI 10.1054/bjps.2000.3565
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
NR 11
TC 25
Z9 33
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0023-852X
J9 LARYNGOSCOPE
JI Laryngoscope
PD JUN
PY 2004
VL 114
IS 6
BP 961
EP 964
DI 10.1097/00005537-200406000-00001
PG 4
WC Medicine, Research & Experimental; Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Otorhinolaryngology
GA 828RZ
UT WOS:000221991900001
PM 15179195
DA 2026-07-24
ER

PT J
AU Sun, DH
   Ju, WN
   Wang, TJ
   Yu, TC
   Qi, BC
AF Sun, Dahui
   Ju, Weina
   Wang, Tiejun
   Yu, Tiecheng
   Qi, Baochang
TI Vacuum sealing drainage therapy in the presence of an external fixation
   device A case report
SO MEDICINE
LA English
DT Article
DE air leakage; external fixation device; rubber strip; vacuum sealing
   drainage (VSD)
ID ASSISTED CLOSURE; WOUND CONTROL; PRESSURE
AB Rationale: Vacuum sealing drainage (VSD) is widely utilized for treating traumatic wounds.
   Patient concerns: It is particularly difficult and time consuming to use in combination with an external fixator.
   Diagnoses: This is because the hardware or pins used for fixation interfere with maintaining a seal, resulting in poor adhesion and subsequent air leakage.
   Interventions: To resolve this problem, we have devised a new method for sealing the wound dressing, while maintaining the required vacuum. When using this technique, a rubber strip is wrapped around each pin in 3 circles outside the plastic drape, and then tightly tied.
   Outcomes: After completing this procedure, a vacuum is obtained, and any air leakage stops. We employed this technique to treat a cohort of patients in our department over a period of two years, and obtained good healing of soft tissue without air leakage, as well as good clinical outcomes.
   Lessons: We have observed that patients treated with this method experienced good clinical outcomes without air leakage, and we recommend its use in treating cases where an external fixation device is present.
C1 [Sun, Dahui; Wang, Tiejun; Yu, Tiecheng; Qi, Baochang] Jilin Univ, Hosp 1, Div Orthoped Traumatol, Changchun, Peoples R China.
   [Ju, Weina] Jilin Univ, Hosp 1, Dept Neurol, Changchun, Peoples R China.
C3 Jilin University; Jilin University
RP Qi, BC (通讯作者)，Jilin Univ, Hosp 1, Div Orthoped Traumatol, Changchun, Peoples R China.
EM qibaochang1@163.com
FU Academy & Research Foundation for Young Scientists [MJR20160015];
   National Natural Science Foundation of China [81500911]; AOTrauma Asia
   Pacific [AOTAP15-01]
FX This project was supported by grants from the Academy & Research
   Foundation for Young Scientists (No. MJR20160015) and the National
   Natural Science Foundation of China (No. 81500911), and also by AOTrauma
   Asia Pacific (Ref: AOTAP15-01).
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   Atiyeh BS, 2005, WORLD J SURG, V29, P131, DOI 10.1007/s00268-004-1082-2
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   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
NR 9
TC 5
Z9 7
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD NOV
PY 2016
VL 95
IS 46
AR e5444
DI 10.1097/MD.0000000000005444
PG 3
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA ED3DV
UT WOS:000388730500064
PM 27861393
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Akbayrak, H
   Tekumit, H
AF Akbayrak, Hakan
   Tekumit, Hayrettin
TI Comparison between Vacuum-Assisted Closure Technique and Conventional
   Approach in Patients with Mediastinitis After Isolated Coronary Artery
   Bypass Graft Surgery
SO BRAZILIAN JOURNAL OF CARDIOVASCULAR SURGERY
LA English
DT Article
DE Coronary Artery Bypass; Mediastinitis. Treatment; Vacuum-Assisted
   Closure
ID RISK-FACTORS; STERNOTOMY; INFECTION
AB Introduction: Median sternotomy is the most preferred approach in heart surgery. Post-sternotomy mediastinitis is a catastrophic and potentially life-threatening complication with an incidence rate of 0.15% to 5%, and its overall mortality rate reaches 47%. In this study, we aimed to compare the results of vacuum-assisted closure technique and the conventional methods on the management of mediastinitis following isolated coronary artery bypass graft surgery.
   Methods: Between February 2001 and July 2013, 32,106 patients who underwent cardiac operations were evaluated retrospectively. One hundred and fourteen patients who developed post-sternotomy mediastinitis were included in this study. The patients were divided into two groups and compared - vacuum-assisted closure group (n= 52, 45.6%) and conventional treatment group (n=62, 54.4%).
   Results: There were no differences between the two groups according to the patients' characteristics, surgical data, and mediastinal cultures. However, we found that total treatment duration for post-sternotomy mediastinitis, time interval from diagnosis to negative culture, hospitalization time, and in-hospital mortality were statistically significantly lower in the vacuum-assisted closure group than in the conventional treatment group (P<0.001, P<0.001, P<0.001, and P=0.03, respectively).
   Conclusion: This study demonstrates that the vacuum-assisted closure technique improves the medical outcome of patients with post- sternotomy mediastinitis compared with the conventional treatment. The vacuum-assisted closure is a safe and more effective treatment modality for patients with post-sternotomy mediastinitis after cardiac surgery with reasonable morbidity and mortality.
C1 [Akbayrak, Hakan] Selcuk Univ, Dept Cardiovasc Surg, Fac Med, Alaaddin Keykubat Campus, TR-42131 Konya, Turkiye.
   [Tekumit, Hayrettin] Bandirma Onyedi Eylul Univ, Dept Cardiovasc Surg, Fac Med, Balikesir, Turkiye.
C3 Selcuk University; Bandirma Onyedi Eylul University
RP Akbayrak, H (通讯作者)，Selcuk Univ, Dept Cardiovasc Surg, Fac Med, Alaaddin Keykubat Campus, TR-42131 Konya, Turkiye.
EM hakanakbayrak@gmail.com
RI Akbayrak, Hakan/GLT-2080-2022
OI Akbayrak, Hakan/0000-0003-1637-6769
CR Bryan A J, 1992, J R Coll Surg Edinb, V37, P305
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NR 18
TC 6
Z9 6
U1 0
U2 2
PU SOC BRASIL CIRURGIA CARDIOVASC
PI SAO PAULO SP
PA RUA AFONSO CELSO, 1178, SAO PAULO SP, 04119-061, BRAZIL
SN 0102-7638
EI 1678-9741
J9 BRAZ J CARDIOV SURG
JI Braz. J. Cardiovasc. Surg.
PY 2023
VL 38
IS 3
BP 353
EP 359
DI 10.21470/1678-9741-2022-0317
PG 7
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA IR4Q5
UT WOS:001168047500007
PM 36692043
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Mcmillan, A
   Yates, G
   Chambers, B
AF Mcmillan, Aj
   Yates, Gd
   Chambers, Ba
TI Vacuum-assisted closure as a component of the management of deep surgery
   site infection after canine cementless total hip replacement
SO AUSTRALIAN VETERINARY JOURNAL
LA English
DT Article
DE infection; negative pressue wound therapy; total hip replacement; vacuum
   assisted closure
ID PRESSURE WOUND THERAPY; DISTAL EXTREMITY; SKIN-GRAFTS; COMPLICATIONS;
   DEVICE
AB This case report presents the incorporation of vacuum-assisted closure (VAC) in the successful management of a deep, multiresistant surgery site infection after cementless total hip replacement (THR) in a dog. It outlines the rationale, technique used and clinical efficacy of the approach. The role of VAC in human orthopedic infections is discussed and potential refinements of the technique are proposed.
C1 [Mcmillan, Aj; Yates, Gd; Chambers, Ba] Ctr Anim Referral & Emergency, Collingwood, Vic, Australia.
RP Mcmillan, A (通讯作者)，Ctr Anim Referral & Emergency, Collingwood, Vic, Australia.
EM amcmillan@carevet.com.au
OI McMillan, Angus/0009-0008-6323-7618
CR Allaith S, 2023, VET SURG, V52, P196, DOI 10.1111/vsu.13885
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NR 25
TC 0
Z9 0
U1 1
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0005-0423
EI 1751-0813
J9 AUST VET J
JI Aust. Vet. J.
PD MAR
PY 2026
VL 104
IS 3
BP 131
EP 136
DI 10.1111/avj.70040
EA NOV 2025
PG 6
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA EU9MZ
UT WOS:001617526100001
PM 41253308
OA Bronze
DA 2026-07-24
ER

PT J
AU Josty, IC
   Ramaswamy, R
   Laing, JHE
AF Josty, IC
   Ramaswamy, R
   Laing, JHE
TI Vacuum-assisted closure: an alternative strategy in the management of
   degloving injuries of the foot
SO BRITISH JOURNAL OF PLASTIC SURGERY
LA English
DT Article
DE degloving injury; reconstruction; vacuum-assisted closure;
   rehabilitation
ID REVASCULARIZATION; SKIN
AB A case of a degloving injury to the foot is presented in a patient who also sustained severe contralateral lower-limb trauma. We report a technique for salvaging the foot by replacing the degloved skin as a full-thickness graft and securing it using the vacuum-assisted closure (VAC (TM)) device. A good outcome was achieved and technical tips are provided to facilitate reproduction of the procedure. (C) 2001 The British Association of Plastic Surgeons.
C1 Morriston Hosp, Welsh Ctr Burns & Plast Surg, Swansea SA6 6NL, W Glam, Wales.
C3 Morriston Hospital
RP Josty, IC (通讯作者)，Morriston Hosp, Welsh Ctr Burns & Plast Surg, Swansea SA6 6NL, W Glam, Wales.
RI Laing, Hamish/AAN-3921-2020
OI Laing, Hamish/0000-0002-5661-7937
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NR 10
TC 28
Z9 40
U1 0
U2 1
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE,
   LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0007-1226
J9 BRIT J PLAST SURG
JI Br. J. Plast. Surg.
PD JUN
PY 2001
VL 54
IS 4
BP 363
EP 365
DI 10.1054/bjps.2000.3565
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 438MH
UT WOS:000169057300019
PM 11355997
OA Bronze
DA 2026-07-24
ER

PT J
AU Blazquez, D
   Ruiz-Contreras, J
   Fernández-Cooke, E
   González-Granado, I
   Delgado, MD
   Menendez, MT
   Rodriguez-Gil, Y
   Ballen, A
   Del Palacio, A
AF Blazquez, Daniel
   Ruiz-Contreras, Jesus
   Fernandez-Cooke, Elisa
   Gonzalez-Granado, Ignacio
   Dolores Delgado, Maria
   Teresa Menendez, Maria
   Rodriguez-Gil, Yolanda
   Ballen, Aida
   Del Palacio, Amalia
TI Lichtheimia corymbifera subcutaneous infection successfully
   treated with amphotericin B, early debridement, and vacuum-assisted
   closure
SO JOURNAL OF PEDIATRIC SURGERY
LA English
DT Article
DE Lichtheimia corymbifera; Mycocladus corymbifer; Absidia corymbifera;
   Zygomycosis; Vacuum-assisted closure; Amphotericin
ID MUCORMYCOSIS; ZYGOMYCOSIS; MANAGEMENT; IDENTIFICATION; MYCOCLADUS
AB Lichtheimia corymbifera (syn. Absidia corymbifera, Mycocladus corymbifer) is an ubiquitous cosmopolitan mold that can cause primary cutaneous and deep tissue infection in healthy individuals. We report a subcutaneous L. corymbifera infection in a 13-year-old immune-competent child, with a severe traumatic injury, with a successful outcome after early diagnosis and treatment with lipid amphotericin B, early debridement, and vacuum-assisted closure (VAC). (C) 2010 Elsevier Inc. All rights reserved.
C1 [Blazquez, Daniel; Ruiz-Contreras, Jesus; Fernandez-Cooke, Elisa; Gonzalez-Granado, Ignacio] Hosp Univ 12 Octubre, Dept Pediat, Madrid, Spain.
   [Dolores Delgado, Maria] Hosp Univ 12 Octubre, Dept Pediat Surg, Madrid, Spain.
   [Teresa Menendez, Maria] Hosp Univ 12 Octubre, Dept Orthopaed Surg, Madrid, Spain.
   [Rodriguez-Gil, Yolanda; Ballen, Aida] Hosp Univ 12 Octubre, Dept Pathol, Madrid, Spain.
   [Del Palacio, Amalia] Hosp Univ 12 Octubre, Dept Microbiol, Madrid, Spain.
C3 Hospital Universitario 12 de Octubre; Hospital Universitario 12 de
   Octubre; Hospital Universitario 12 de Octubre; Hospital Universitario 12
   de Octubre; Hospital Universitario 12 de Octubre
RP Blazquez, D (通讯作者)，Hosp Univ 12 Octubre, Dept Pediat, Madrid, Spain.
EM danielblazquez@hotmail.com
RI ; Blázquez-Gamero, Daniel/ABE-9367-2020
OI Rodriguez Gil, Yolanda/0000-0002-4811-5486; RUIZ-CONTRERAS,
   JESUS/0000-0002-2788-7524; Blázquez-Gamero, Daniel/0000-0001-6483-8329;
   Fernández-Cooke, Elisa/0000-0002-5921-8261
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   Bialek R, 2005, J CLIN PATHOL, V58, P1180, DOI 10.1136/jcp.2004.024703
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   Chamilos G, 2008, CLIN INFECT DIS, V47, P503, DOI 10.1086/590004
   Garbino J, 2005, J Infect, V51, pe135, DOI 10.1016/j.jinf.2004.11.002
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   Schwarz P, 2006, J CLIN MICROBIOL, V44, P340, DOI 10.1128/JCM.44.2.340-349.2006
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   Spellberg B, 2009, CLIN INFECT DIS, V48, P1743, DOI 10.1086/599105
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NR 11
TC 13
Z9 14
U1 0
U2 5
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0022-3468
J9 J PEDIATR SURG
JI J. Pediatr. Surg.
PD DEC
PY 2010
VL 45
IS 12
BP E13
EP E15
DI 10.1016/j.jpedsurg.2010.08.011
PG 3
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA 688SM
UT WOS:000284873300004
PM 21129524
DA 2026-07-24
ER

PT J
AU Song, F
   Liu, ZZ
AF Song, Feng
   Liu, Zhenzhong
TI Bilateral-pectoral major muscle advancement flap combined with
   vacuum-assisted closure therapy for the treatment of deep sternal wound
   infections after cardiac surgery
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
DE Cardiac surgery; Deep sternal wound infections; Bilateral-pectoral major
   muscle advancement flap; Vacuum-assisted closure therapy
ID RISK-FACTORS; RECONSTRUCTION
AB Objectives The median sternotomy is the most common surgical approach for cardiac surgery. Deep sternal wound infection is a fatal complication after median sternotomy. The aim of this study was to evaluate the therapeutic effect of Bilateral-pectoral major muscle advancement flap combined with Vacuum-assisted closure therapy on rehabilitation for the treatment of deep sternal wound infection after cardiac surgery. Methods Between January 2016 to January 2018, 21 patients (10 males, 11 females) with deep sternal wound infection after cardiac surgery underwent Bilateral-pectoral major muscle advancement flap combined with Vacuum-assisted closure therapy. These patients were followed-up 12 months postoperative. The patient characteristics, duration of vacuum-assisted closure therapy, the mean hospital stay, postoperative complications, long-term survival of patients were retrospectively analyzed. Results Most patients undergone 1-3 times vacuum-assisted closure treatment sessions before closure. All patients were cured to discharge, the mean hospital stay was 21.1 days. Most patients' healing wounds were first-stage healing, only one patient's wound was second-stage healing, none was third-stage healing. One patient developed pulmonary infection and respiratory failure during the 12-month follow-up. None of the patients died during follow-up. Conclusions Bilateral-pectoral major muscle advancement flap combined with Vacuum-assisted closure therapy for the treatment of deep sternal wound infections after cardiac surgery can shorten the hospital stays and few complications. However, this is a retrospective case series presentation with no comparison group, the number of inferences is limited, so further large-scale controlled studies are needed.
C1 [Song, Feng; Liu, Zhenzhong] Shandong Univ, Hosp 2, Cheeloo Coll Med, Dept Plast Surg, 247 Beiyuan St, Jinan 250000, Shandong, Peoples R China.
C3 Shandong University
RP Liu, ZZ (通讯作者)，Shandong Univ, Hosp 2, Cheeloo Coll Med, Dept Plast Surg, 247 Beiyuan St, Jinan 250000, Shandong, Peoples R China.
EM drliuzhenzhong@163.com
CR Erdmann D, 2000, CHIRURG, V71, P1156, DOI 10.1007/s001040051194
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   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
NR 12
TC 7
Z9 11
U1 0
U2 4
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD AUG 27
PY 2020
VL 15
IS 1
AR 227
DI 10.1186/s13019-020-01264-2
PG 8
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA NK7FP
UT WOS:000566899000001
PM 32854735
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Senchenkov, A
   Knoetgen, J
   Chrouser, KL
   Nehra, A
AF Senchenkov, A
   Knoetgen, J
   Chrouser, KL
   Nehra, A
TI Application of vacuum-assisted closure dressing in penile skin graft
   reconstruction
SO UROLOGY
LA English
DT Article
AB Introduction. Skin grafting of penile defects is difficult because of the flexibility of the underlying recipient bed. This leads to disruption of the vascular ingrowth into the skin graft and compromises the results of the reconstruction.
   Technical Considerations. We successfully used a vacuum-assisted closure dressing with an incorporated wooden framework to secure penile skin grafts in place during the early postoperative period.
   Conclusions. A vacuum-assisted closure dressing can be used successfully to secure large and circumferential skin grafts, as well as skin grafts on concealed penises.
C1 Mayo Clin, Dept Plast & Reconstruct Surg, Rochester, MN 55905 USA.
   Mayo Clin, Dept Urol, Rochester, MN 55905 USA.
C3 Mayo Clinic; Mayo Clinic
RP Senchenkov, A (通讯作者)，Mayo Clin, Dept Plast & Reconstruct Surg, Mayo bldg W1244,200 1st St SW, Rochester, MN 55905 USA.
EM senchenkov@yahoo.com
CR Black PC, 2004, J UROLOGY, V172, P976, DOI 10.1097/01.ju.0000133972.65501.44
   EHRLICH RM, 1999, RECONSTRUCTIVE PLAST, V1, P397
   FURNAS DW, 1980, CLIN PLAST SURG, V7, P235
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   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
NR 7
TC 29
Z9 31
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0090-4295
EI 1527-9995
J9 UROLOGY
JI Urology
PD FEB
PY 2006
VL 67
IS 2
BP 416
EP 419
DI 10.1016/j.urology.2005.08.037
PG 4
WC Urology & Nephrology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Urology & Nephrology
GA 024EO
UT WOS:000236178500042
PM 16461101
DA 2026-07-24
ER

PT J
AU Lou, JQ
   Zhu, XY
   Xiang, ZY
   Fan, YF
   Song, JY
   Huang, N
   Li, JL
   Jin, GY
   Cui, SY
AF Lou, Jiaqi
   Zhu, Xiaoyu
   Xiang, Ziyi
   Fan, Youfen
   Song, Jingyao
   Huang, Neng
   Li, Jiliang
   Jin, Guoying
   Cui, Shengyong
TI The efficacy and safety of negative pressure wound therapy in paediatric
   burns: a systematic review and meta-analysis of randomized controlled
   trials
SO BMC PEDIATRICS
LA English
DT Article
DE Negative pressure wound therapy; Paediatric burns; Vacuum sealing
   drainage; Healing time; Complications; Meta-analysis
ID KNEE ARTHROPLASTY; SKIN-GRAFTS; INSTILLATION; DRESSINGS
AB BackgroundAlthough the effective application of negative pressure wound therapy (NPWT) has been exemplified in diverse clinical studies, its potential and safety, specifically regarding paediatric burns, are yet to be fully confirmed. Our most recent systematic review and meta-analysis strive to investigate the impact of NPWT within the realm of paediatric burns. MethodsWe sourced relevant articles from databases including PubMed, Embase, the Cochrane Database, Web of Science, the International Clinical Trials Registry Platform, China National Knowledge Infrastructureris, the VIP Database for Chinese Technical Periodicals, and the Wanfang database. We defined the primary outcome measure as the healing time, while healing rate, numbers of dressing changes, detection rate of positive bacteria, incidence rate of adverse reactions, scar scale scores, and treatment costs were considered as secondary outcome measures. Pooling of data was conducted and the results were articulated as relative risk (RR), mean difference (MD), and standardized mean difference (SMD), all with a 95% confidence interval (CI). ResultsIn this systematic review and meta-analysis, a total of 12 studies involving 1033 individuals were examined, including 559 paediatric burn patients who underwent NPWT (referred to as the treatment group) and 543 patients who received treatments other than NPWT (referred to as the control group). The amalgamated data from these studies exhibited that the treatment group experienced significant reductions in healing time (SMD = -1.60; 95% CI: -2.26 - -0.95; p < 0.001, I2 = 92.8%), the number of required dressing changes (SMD = -4.6; 95% CI: -5.84 - -3.36; p < 0.001, I2 = 92.4%), positive bacteria detection rate (RR = 0.61; 95% CI: 0.26-1.46; p = 0.004, I2 = 81.8%), incidence of adverse reactions (RR = 0.61; 95% CI: 0.33-1.12; p = 0.005, I2 = 68%), scar scale scores (SMD = -1.66; 95% CI: -2.54 - -0.79; p < 0.001, I2 = 89.4%), as well as in treatment costs (SMD = 0.92; 95% CI: -1.66-3.49; p < 0.001, I2 = 98.4%). Additionally, these individuals showed an increased rate of healing (RR = 1.17; 95% CI: 0.99-1.39; p < 0.001, I2 = 78%). Subgroup analysis did not find that the degree of burn was one of the sources of high heterogeneity. ConclusionOur meta-analysis points to the effectiveness of NPWT in treating paediatric burns. Notably, it significantly mitigates healing duration, frequency of dressing alterations, positive bacterial detection rate, adverse reactions incidence, scar scale scores and treatment costs, all while propelling the acceleration of wound healing.
C1 [Lou, Jiaqi; Fan, Youfen; Huang, Neng; Li, Jiliang; Jin, Guoying; Cui, Shengyong] Ningbo No 2 Hosp, Burn Dept, 41 Northwest St, Ningbo 315010, Zhejiang, Peoples R China.
   [Zhu, Xiaoyu] Ningbo Univ, Hlth Sci Ctr, Ningbo, Zhejiang, Peoples R China.
   [Xiang, Ziyi] Univ Bonn, Fac Med, Dept Psychiat & Psychotherapy, Sect Med Psychol, D-53127 Bonn, Germany.
   [Song, Jingyao] Wenzhou Med Univ, Sch Mental Hlth, Whenzhou, Zhejiang, Peoples R China.
C3 Ningbo University; University of Bonn; Wenzhou Medical University
RP Cui, SY (通讯作者)，Ningbo No 2 Hosp, Burn Dept, 41 Northwest St, Ningbo 315010, Zhejiang, Peoples R China.
EM csy00544@163.com
RI Lou, Jiaqi/GSN-0304-2022
OI Lou, Jiaqi/0000-0003-1316-7507
FU Project of NINGBO Leading Medical & Health Discipline
FX Not applicable.
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NR 70
TC 13
Z9 15
U1 1
U2 7
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2431
J9 BMC PEDIATR
JI BMC Pediatr.
PD DEC 18
PY 2024
VL 24
IS 1
AR 807
DI 10.1186/s12887-024-05302-z
PG 27
WC Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics
GA P9K8J
UT WOS:001381014700005
PM 39696096
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Wang, Y
   Beekman, J
   Hew, J
   Jackson, S
   Issler-Fisher, AC
   Parungao, R
   Lajevardi, SS
   Li, Z
   Maitz, PKM
AF Wang, Yiwei
   Beekman, Joanneke
   Hew, Jonathan
   Jackson, Stuart
   Issler-Fisher, Andrea C.
   Parungao, Roxanne
   Lajevardi, Sepher S.
   Li, Zhe
   Maitz, Peter K. M.
TI Burn injury: Challenges and advances in burn wound healing, infection,
   pain and scarring
SO ADVANCED DRUG DELIVERY REVIEWS
LA English
DT Review
DE Severe burn injuries; Burn wound infections; Burn pain management;
   Scarring; Skin tissue engineering; Stem cells; Negative pressure wound
   therapy; Laser therapy for scarring
ID ABLATIVE FRACTIONAL LASER; PULSED-DYE-LASER; DERMAL REGENERATION
   TEMPLATE; VACUUM-ASSISTED CLOSURE; COLLAGEN-ELASTIN MATRIX;
   PARTIAL-THICKNESS BURNS; TISSUE-ENGINEERED SKIN; AUTOLOGOUS FAT GRAFT;
   NEGATIVE-PRESSURE; HYPERTROPHIC SCARS
AB Severe burn injuries are the most traumatic and physically debilitating injuries affecting nearly every organ system and leading to significant morbidity and mortality. Early bum wound excision and skin grafting are common clinical practices that have significantly improved the outcomes for severe burn injured patients by reducing mortality rate and days of hospital stay. However, slow wound healing, infection, pain, and hypertrophic scarring continue to remain a major challenge in burn research and management. In the present article, we review and discuss issues in the current treatment of burn injuries; the advances and novel strategies developed in the past decade that have improved burn management; and also, pioneer ideas and studies in burn research which aims to enhance bum wound care with a focus on burn wound infection, pain management, treatments for scarring and skin tissue engineering. (C) 2017 Elsevier B.V. All rights reserved.
C1 [Wang, Yiwei; Beekman, Joanneke; Hew, Jonathan; Jackson, Stuart; Parungao, Roxanne; Li, Zhe; Maitz, Peter K. M.] Univ Sydney, Concord Hosp, ANZAC Res Inst, Burns Res Grp, Concord West, NSW 2139, Australia.
   [Issler-Fisher, Andrea C.; Lajevardi, Sepher S.; Li, Zhe; Maitz, Peter K. M.] Concord Hosp, Burns & Reconstruct Surg Unit, Concord West, NSW 2139, Australia.
C3 University of Sydney; ANZAC Research Institute; Concord Repatriation
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RP Maitz, PKM (通讯作者)，Univ Sydney, Concord Hosp, Sydney, NSW, Australia.
EM peter.maitz@sydney.edu.au
RI ; Maitz, Peter/GQI-2475-2022; Maitz, Joanneke/CAG-5361-2022; Wang,
   Yiwei/AAE-9739-2021; Hew, Jonathan/KVA-6055-2024
OI Lajevardi, Sepehr Seyed/0000-0001-6228-4596; Li,
   Zhe/0000-0001-7988-1012; Maitz, Peter/0000-0002-8257-7414; Maitz,
   Joanneke/0000-0001-5276-9637; Wang, Yiwei/0000-0001-6585-6641; 
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   Yeong WY, 2014, HIGH VALUE MANUFACTURING: ADVANCED RESEARCH IN VIRTUAL AND RAPID PROTOTYPING, P65, DOI 10.1201/b15961-14
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   Zhang F, 2015, J SURG RES, V195, P344, DOI 10.1016/j.jss.2014.12.025
   Zhang GY, 2009, MED HYPOTHESES, V73, P332, DOI 10.1016/j.mehy.2008.10.037
   Zhang J, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0116888
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   Zhibo X, 2009, PLAST RECONSTR SURG, V124, P275, DOI DOI 10.1097/PRS.0B013
   Zhong SP, 2010, WIRES NANOMED NANOBI, V2, P510, DOI 10.1002/wnan.100
   Zor F, 2010, BURNS, V36, P501, DOI 10.1016/j.burns.2009.08.007
NR 294
TC 564
Z9 645
U1 27
U2 676
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 0169-409X
EI 1872-8294
J9 ADV DRUG DELIVER REV
JI Adv. Drug Deliv. Rev.
PD JAN 1
PY 2018
VL 123
BP 3
EP 17
DI 10.1016/j.addr.2017.09.018
PG 15
WC Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pharmacology & Pharmacy
GA FU1YN
UT WOS:000423645500002
PM 28941987
HC Y
HP N
DA 2026-07-24
ER

PT J
AU Özkan, B
   Kapdagli, M
   Duman, S
   Demir, A
   Toker, A
AF Ozkan, Berker
   Kapdagli, Murat
   Duman, Salih
   Demir, Adalet
   Toker, Alper
TI Endobronchial valve and vacuum-assisted closure treatment for a
   complicated air leak problem after cardiac surgery
SO TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND
   CARDIOVASCULAR SURGERY
LA English
DT Article
DE Mediastinal infection; pleural air leak; surgery complications
ID BRONCHOPLEURAL FISTULAS; COILS
AB In this article, we report a 57-year-old male patient who developed mediastinitis due to massive air leak after coronary bypass surgery and deteriorated with endobronchial valve application. The patient underwent a long and complicated treatment process with open drainage and vacuum-assisted closure applications and recovered. Although endobronchial valve applications are efficient in the treatment of prolonged air leak, we recommend considering open drainage and vacuum-assisted closure if infectious complications occur.
C1 [Ozkan, Berker; Kapdagli, Murat; Duman, Salih; Demir, Adalet; Toker, Alper] Istanbul Univ, Istanbul Fac Med, Dept Thorac Surg, Istanbul, Turkey.
C3 Istanbul University
RP Özkan, B (通讯作者)，Istanbul Univ, Istanbul Tip Fak, Gogus Cerrahisi Anabilim Dali, TR-34093 Istanbul, Turkey.
EM berkerozkan@yahoo.com
RI Özkan, Berker/AAE-8781-2020; /AAW-1876-2020; Demir, Adalet/PGF-0550-2026
CR Ferguson JS, 2006, CHEST, V129, P479, DOI 10.1378/chest.129.2.479
   Lin J, 2004, ANN THORAC SURG, V77, P326, DOI 10.1016/S0003-4975(03)00750-1
   PONN RB, 1993, ANN THORAC SURG, V56, P1343, DOI 10.1016/0003-4975(93)90679-C
   Varoli F, 1998, ANN THORAC SURG, V65, P807, DOI 10.1016/S0003-4975(97)01427-6
   Watanabe S, 2003, THORAC CARDIOV SURG, V51, P106, DOI 10.1055/s-2003-38981
NR 5
TC 0
Z9 0
U1 0
U2 3
PU BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK
PI ATASEHIR
PA ORNEK MH DR SUPHI EZGI SK SARAY APT NO 11 D 6, ATASEHIR, ISTANBUL 34704,
   TURKEY
SN 1301-5680
J9 TURK GOGUS KALP DAMA
JI Turk Gogus Kalp Damar Cerrahisi Derg.
PD JUL
PY 2016
VL 24
IS 3
BP 589
EP 591
DI 10.5606/tgkdc.dergisi.2016.12211
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DY6XJ
UT WOS:000385272300032
OA hybrid
DA 2026-07-24
ER

PT J
AU Shvartsman, HS
   Langstein, H
   Worley, C
   Malpica, A
   Ramondetta, LM
AF Shvartsman, HS
   Langstein, H
   Worley, C
   Malpica, A
   Ramondetta, LM
TI Use of a vacuum-assisted closure device in the treatment of recurrent
   Paget's disease of the vulva
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Editorial Material
AB BACKGROUND: Paget's disease of the vulva is a rare malignancy for which common recurrence is related to inadequate surgical margins. Excision with adequate surgical margins might leave a large defect that does not readily heal.
   CASE: A 41-year-old woman with recurrent Paget's disease of the vulva underwent a skinning excision of the vulva and perineum. A vacuum-assisted closure device was placed on the wound until final pathologic analysis confirmed the adequacy of surgical margins.
   CONCLUSION: The vacuum-assisted closure device not only allowed us to safely temporize wound closure until the final histopathologic results, but also helped secure the skin graft to the large and irregular surface. Additional studies are needed to determine the effectiveness of vacuum-assisted closure device therapy in Paget's disease of the vulva.
C1 Univ Texas, MD Anderson Canc Ctr, Dept Gynecol Oncol, Houston, TX 77030 USA.
   Univ Texas, MD Anderson Canc Ctr, Dept Plast Surg, Houston, TX 77030 USA.
   Univ Texas, MD Anderson Canc Ctr, Dept Nursing Wound Ostomy & Continence, Houston, TX 77030 USA.
   Univ Texas, MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA.
C3 University of Texas System; UTMD Anderson Cancer Center; University of
   Texas System; UTMD Anderson Cancer Center; University of Texas System;
   UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson
   Cancer Center
RP Shvartsman, HS (通讯作者)，Univ Texas, MD Anderson Canc Ctr, Dept Gynecol Oncol, 1515 Holcombe Blvd,Unit 440, Houston, TX 77030 USA.
EM hshvarts@mdanderson.org
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Choi JB, 2001, BJU INT, V88, P297, DOI 10.1046/j.1464-410x.2001.02326.x
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   Tjalma WA, 2001, EUR J GYNAECOL ONCOL, V22, P13
NR 8
TC 15
Z9 23
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0029-7844
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD NOV
PY 2003
VL 102
IS 5
BP 1163
EP 1166
DI 10.1016/S0029-7844(03)00716-6
PN 2
PG 4
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 738NJ
UT WOS:000186294500015
PM 14607043
DA 2026-07-24
ER

PT J
AU Polzer, H
   Mutschler, W
AF Polzer, H.
   Mutschler, W.
TI Vacuum assisted closure therapy. Management of a severe blast injury to
   the lower limb
SO UNFALLCHIRURG
LA German
DT Article
DE Blast injury; Lower extremity; Negative pressure wound therapy; Soft
   tissue injury; Wound management
ID SOFT-TISSUE INJURY; OPEN FRACTURES; NEGATIVE-PRESSURE; WOUND CONTROL
AB This article reports the case of a 23-year-old woman who sustained severe soft tissue injuries with open fractures of the left distal femur, the left proximal tibia, a subtotal amputation of the left foot with injuries to the anterior and posterior tibial artery due to a bomb blast. When the patient was transferred to our hospital 17 days after the trauma, all primarily closed wounds were severely infected. The fractures were treated by external fixateur and k-wire fixation. After debridement and initiation of negative pressure therapy the anterior tibial artery was reconstructed after 3 days and partial wound closure by a rectus abdominis muscle flap was achieved after 19 days. After almost total wound closure was accomplished open reduction internal fixation (ORIF) was performed for the distal femur fracture and a modification of the external fixateur for the tibial and foot fractures. The negative pressure therapy is an important component for treatment of complex soft tissue injuries and open fractures; however, it must be embedded in an interdisciplinary treatment plan with well-defined treatment goals.
C1 [Polzer, H.; Mutschler, W.] Klinikum Ludwig Maximilians Univ Munchen, Chirurg Klin & Poliklin, D-80336 Munich, Germany.
C3 University of Munich
RP Polzer, H (通讯作者)，Klinikum Ludwig Maximilians Univ Munchen, Chirurg Klin & Poliklin, Campus Innenstadt,Nussbaumstr 20, D-80336 Munich, Germany.
EM hans.polzer@med.uni-muenchen.de
RI Polzer, Hans/Q-3864-2019
OI Polzer, Hans/0000-0002-6713-4017
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Evans D, 2001, BRIT J PLAST SURG, V54, P238, DOI 10.1054/bjps.2001.3547
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
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   Holle G, 2007, UNFALLCHIRURG, V110, P289, DOI 10.1007/s00113-007-1265-z
   Kamolz LP, 2004, BURNS, V30, P253, DOI 10.1016/j.burns.2003.12.003
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   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
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NR 11
TC 1
Z9 1
U1 0
U2 7
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0177-5537
J9 UNFALLCHIRURG
JI Unfallchirurg
PD SEP
PY 2012
VL 115
IS 9
BP 792
EP 797
DI 10.1007/s00113-012-2210-3
PG 6
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA 998JV
UT WOS:000308235200008
PM 22935897
DA 2026-07-24
ER

PT J
AU Prasetyono, TOH
   Rini, IS
   Wibisono, C
AF Prasetyono, Theddeus O. H.
   Rini, Irena Sakura
   Wibisono, Cindy
TI EASEPort NPWT System to Enhance Skin Graft Survival - A Simple Assembly
SO INTERNATIONAL SURGERY
LA English
DT Article
DE Bandages; Foreign body; Exudate and transudate; Skin transplantation
   Wound; healing
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; NEGATIVE-PRESSURE;
   TRIAL; MODEL
AB Skin graft has been known to be prone to failure. This study was aimed to make a simplification of the negative pressure wound therapy (NPWT), which follows EASEPort (effective, affordable, safe, easily handled, and portable) concept to support the take of skin graft. The design of the EASEPort-NPWT was then made and technically verified. Thereafter, an animal experimental study comparing the EASEPort-NPWT to the classic tie-over technique on skin graft over exudative wound was conducted. The EASEPortNPWT was verified to be able to yield and sustain the subatmospheric pressure needed. In the animal study, the treatment group showed better skin graft survival rate (97.55 +/- 11.18% take) than the control group (54.88 +/- 19.73%) on day-7. Histopathology examination showed good quality of the skin structures taken from the treatment group, which was better than the structures of the skin in the control group. In summary, this study has been able to fulfill its objective to create a device following EASEPort concept. Subsequently, the EASEPort-NPWT was able to enhance skin graft survival rate in exudative wound.
C1 [Prasetyono, Theddeus O. H.; Wibisono, Cindy] Univ Indonesia, Cipto Mangunkusumo Hosp, Dept Surg, Div Plast Surg,Fac Med, Jakarta 13410, Indonesia.
   [Rini, Irena Sakura] Dharmais Hosp, Dept Surg, Div Plast Surg, Jakarta, Indonesia.
C3 University of Indonesia; Dr. Cipto Mangunkusumo National Public
   Hospital; Dharmais Hospital
RP Prasetyono, TOH (通讯作者)，Univ Indonesia, Cipto Mangunkusumo Hosp, Dept Surg, Div Plast Surg, Jl Diponegoro 71, Jakarta 13410, Indonesia.
EM teddyohprasetyono@yahoo.com
RI Prasetyono, Theddeus/GSD-6856-2022
OI Rini, Irena Sakura/0000-0003-4173-5911
CR [Anonymous], 2004, VAC ASS CLOS THER WO, P1
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NR 19
TC 3
Z9 3
U1 0
U2 1
PU INT COLLEGE OF SURGEONS
PI CHICAGO
PA 1516 N LAKE SHORE DR, CHICAGO, IL 60610 USA
SN 0020-8868
J9 INT SURG
JI Int. Surg.
PD MAR
PY 2015
VL 100
IS 3
BP 518
EP 523
DI 10.9738/INTSURG-D-14-00029.1
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CE2RX
UT WOS:000351665100024
PM 25785338
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Juntermanns, B
   Cyrek, AE
   Bernheim, J
   Hoffmann, JN
AF Juntermanns, B.
   Cyrek, A. E.
   Bernheim, J.
   Hoffmann, J. N.
TI Management of lymphatic fistulas in the groin from a surgeon's
   perspective
SO CHIRURG
LA German
DT Article
ID VACUUM-ASSISTED-CLOSURE; ARTERIAL RECONSTRUCTION; DOXYCYCLINE TREATMENT;
   VASCULAR-SURGERY; VARICOSE-VEINS; THERAPY; COMPLICATIONS; LYMPHORRHEA;
   LYMPHADENECTOMY; RADIOTHERAPY
AB The postoperative occurrence of lymph fistulas in the groin is a complication that should be taken seriously. These fistulas cause an increase in morbidity and can support local and ascending infections. The treatment of this complication ranges from conservative procedures, such as compression dressings and bed rest to operative treatment with detection of the fistulas and ligation, negative pressure wound therapy (NPWT) or even muscle flaps. This review provides an overview of current therapeutic modalities.
   On the basis of a current literature search via PubMed, we identified possible treatment options, which are described in this article.
   The conservative treatment options presented still have an importance in treating groin fistulas. A selection of safe and effective interventional and operative treatments is presented.
   If there are indications for an interventional or operative treatment a variety of safe and effective therapies are available, which can significantly reduce the length of hospital stay. The option of treatment using a muscle flap is of value as a last resort in the treatment of infected vascular prosthesis in the groin of Szilagyi type III and should be used when necessary.
C1 [Juntermanns, B.; Cyrek, A. E.; Bernheim, J.] Univ Duisburg Essen, Univ Klinikum Essen, Klin Allgemein Viszeral & Transplantat Chirurg, Essen, Germany.
   [Hoffmann, J. N.] Elisabeth Krankenhaus Essen, Contilia Herz & Gefasszentrum, Klin Gefasschirurg & Phlebol, Essen, Germany.
C3 University of Duisburg Essen
RP Juntermanns, B (通讯作者)，Univ Duisburg Essen, Univ Klinikum Essen, Klin Allgemein Viszeral & Transplantat Chirurg, Essen, Germany.
EM benjamin.juntermanns@uk-essen.de
RI Cyrek, Anna/NAZ-7454-2025
OI Cyrek, Anna/0000-0001-5611-809X
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NR 30
TC 8
Z9 8
U1 0
U2 6
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0009-4722
EI 1433-0385
J9 CHIRURG
JI Chirurg
PD JUL
PY 2017
VL 88
IS 7
BP 582
EP 586
DI 10.1007/s00104-017-0378-3
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FA2ZL
UT WOS:000405310600006
PM 28180975
DA 2026-07-24
ER

PT J
AU Heller, L
   Ballo, MT
   Cormier, JN
   Oates, SD
   Butler, CE
AF Heller, Lior
   Ballo, Matthew T.
   Cormier, Janice N.
   Oates, Scott D.
   Butler, Charles E.
TI Staged reconstruction for resection wounds in sarcoma patients treated
   with brachytherapy
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE surgical flaps; sarcoma; brachytherapy; radiotherapy; microsurgery;
   wound healing; VAC; vacuum-assisted closure
ID SOFT-TISSUE SARCOMA; ADJUVANT RADIATION-THERAPY; PRIOR SURGERY;
   EXTREMITY; COMPLICATIONS; IRRADIATION; MANAGEMENT
AB Adjuvant brachytherapy reduces local recurrences following wide local excision of large, high-grade sarcomas; but its use with immediate flap reconstruction is associated with a high wound complication rate following previous radiotherapy. To avoid flap irradiation and reduce wound-healing morbidity, a treatment strategy using negative-pressure wound therapy (NPWT) for temporary wound coverage during brachytherapy followed by delayed flap reconstruction was used in 3 previously irradiated sarcoma patients. NPWT was continued after brachytherapy catheter removal to stimulate vascularization, granulation, and wound contraction. Flap reconstructions were performed after the adequacy of the resection margins was pathologically confirmed and the wound bed appeared grossly vascularized. Prior to reconstruction, 2 patients required additional excision of positive or close permanent-section surgical margins. There were no major wound-healing complications during 9-18 months' follow-up. Staged closure using this approach may have advantages over immediate flap reconstruction in some sarcoma patients. Potential advantages include avoiding flap irradiation, reducing wound size and magnitude of the reconstructive procedure, and ensuring tumor-free surgical margins before definitive reconstruction.
C1 [Heller, Lior; Oates, Scott D.; Butler, Charles E.] Univ Texas MD Anderson Canc Ctr, Dept Plast Surg, Houston, TX 77030 USA.
   [Ballo, Matthew T.] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX 77030 USA.
   [Cormier, Janice N.] Univ Texas MD Anderson Canc Ctr, Dept Surg Oncol, Houston, TX 77030 USA.
C3 University of Texas System; UTMD Anderson Cancer Center; University of
   Texas System; UTMD Anderson Cancer Center; University of Texas System;
   UTMD Anderson Cancer Center
RP Butler, CE (通讯作者)，Univ Texas MD Anderson Canc Ctr, Dept Plast Surg, Unit 443,1515 Holcombe Blvd, Houston, TX 77030 USA.
EM cbutler@mdanderson.org
RI Butler, Charles/GOH-1645-2022
OI Ballo, Matthew/0000-0003-0270-8726
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NR 15
TC 13
Z9 14
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-7043
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD JAN
PY 2008
VL 60
IS 1
BP 58
EP 63
DI 10.1097/01.sap.0000258956.66990.9a
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 243UL
UT WOS:000251822700016
PM 18281799
DA 2026-07-24
ER

PT J
AU Angarita, AM
   Jayakumaran, J
   Di Mascio, D
   Berghella, V
AF Angarita, Ana M.
   Jayakumaran, Jenani
   Di Mascio, Daniele
   Berghella, Vincenzo
TI Prophylactic negative pressure wound therapy on wound complications
   after cesarean delivery in women with obesity: a meta-analysis of
   randomized controlled trials
SO AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
LA English
DT Review
DE cesarean delivery; negative pressure wound therapy; obesity; surgical
   site infection; wound; wound complications
ID SURGICAL-SITE INFECTION; RISK; SECTION
AB OBJECTIVE: This systematic review and meta-analysis of randomized controlled trials aimed to assess whether negative pressure wound therapy affects the rate of wound complications when applied to women with obesity after cesarean delivery compared with standard postoperative dressings.
   DATA SOURCES: This research used PubMed, Scopus, ClinicalTrials.gov, and the Cochrane Central Register of Controlled Trials as electronic databases, from the inception of each database to January 2021, with randomized controlled trial as the publication type. There was no restriction applied for language or geographic location.
   STUDY ELIGIBILITY CRITERIA: The selection criteria included only randomized controlled trials comparing the effect of negative pressure wound therapy with that of standard dressings on wound complications in women with obesity undergoing cesarean delivery.
   METHODS: The primary outcome was a wound complication composite outcome (wound infection, separation or dehiscence, hematoma, seroma, or readmission secondary to a wound concern). The wound complication composite was analyzed by counting events once per patient. The summary measures were reported as relative risk or as mean difference with 95% confidence intervals using the random-effects model of DerSimonian and Laird. An I squared (Higgins I-2) value of >0% was used to identify heterogeneity.
   RESULTS: Overall, 11 randomized controlled trials, which included 5746 participants with obesity undergoing cesarean delivery, were included. Of those participants, 2869 (49.9%) were randomized to the intervention group (negative pressure wound therapy), and 2877 (50.1%) were randomized to the control group (standard dressing). Prophylactic negative pressure wound therapy was not associated with a significant change in the rate of wound complications (relative risk, 1.00; 95% confidence interval, 0.81-1.23) compared with standard postoperative dressings. However, the use of negative pressure wound therapy decreased the rate of wound infections (relative risk, 0.79; 95% confidence interval, 0.66-0.96) and increased the frequency of skin reactions (relative risk, 4.59; 95% confidence interval, 1.29-16.38). Negative pressure wound therapy did not result in a significant difference in the rate of dehiscence, hematoma, seroma, readmission, reoperation, and antibiotic use for wound infection.
   CONCLUSION: Compared with standard postoperative incision dressings, negative pressure wound therapy did not affect the rate of wound complications but decreased the frequency of wound infections when applied to women with obesity after cesarean delivery. However, results should be interpreted with caution, as wound infection outcome includes different defi-nitions per the individual trials.
   CONDENSATION: Prophylactic negative pressure wound therapy has no effect on overall wound complications in women with obesity after cesarean delivery compared with standard dressings.
C1 [Angarita, Ana M.; Jayakumaran, Jenani; Berghella, Vincenzo] Thomas Jefferson Univ, Div Maternal Fetal Med, Dept Obstet & Gynecol, Sidney Kimmel Med Coll, Philadelphia, PA 19107 USA.
   [Di Mascio, Daniele] Sapienza Univ Rome, Dept Maternal & Child Hlth & Urol Sci, Rome, Italy.
C3 Thomas Jefferson University; Sapienza University Rome
RP Berghella, V (通讯作者)，Thomas Jefferson Univ, Div Maternal Fetal Med, Dept Obstet & Gynecol, Sidney Kimmel Med Coll, Philadelphia, PA 19107 USA.
EM vincenzo.berghella@jefferson.edu
RI Di Mascio, Daniele/AAK-2534-2020; Berghella, Vincenzo/K-8634-2018
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NR 34
TC 9
Z9 10
U1 0
U2 5
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 2589-9333
J9 AM J OBST GYNEC MFM
JI Amer. J. Obstet. Gynecol. MFM
PD MAY
PY 2022
VL 4
IS 3
AR 100617
DI 10.1016/j.ajogmf.2022.100617
EA APR 2022
PG 13
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 1F0KB
UT WOS:000794865000032
PM 35283349
DA 2026-07-24
ER

PT J
AU Yu, YL
   Xia, JQ
   Jiang, Q
AF Yu, Yalu
   Xia, Jiaqi
   Jiang, Qin
TI Causes of Mediastinitis and Its Surgical Treatment
SO HEART SURGERY FORUM
LA English
DT Review
DE mediastinitis; risk factors; sternal fixation devices
ID STERNAL WOUND-INFECTION; POST-STERNOTOMY MEDIASTINITIS; CARDIAC-SURGERY;
   RISK-FACTORS; POSTOPERATIVE MEDIASTINITIS; STAPHYLOCOCCUS-AUREUS;
   CLINICAL-FEATURES; PLATE FIXATION; CLOSURE; TRANSFUSION
AB Mediastinitis remains a potentially fatal complication of cardiac surgery. This study reviews the risk factors for mediastinitis after cardiac surgery, and discusses current treatment and prevention of this complication. This review explores three major independent risk factors for mediastinitis including individual patient factors, surgical procedures and microbiology. The perioperative period is influenced by the utilization of the internal mammary artery in conjunction with coronary artery bypass grafting, sternal fixation, vacuum-assisted closure, and negative pressure wound therapy. Staphylococcus aureus and Staphylococcus epidermidis are frequently encountered microorganisms. Additionally, aerobic gram-negative microorganisms and other infrequent microorganisms are also exhibiting a rising trend. Since sternal fixation devices effectively enhance sternal stability, alleviate wound pain, and decrease the occurrence of postoperative mediastinitis, they have been specifically incorporated into certain therapeutic and prophylactic approaches for addressing this complication. Despite the heightened awareness regarding mediastinitis, the large proportion of individuals at risk underscores the crucial need for rigorous monitoring of potential risk factors, posing a significant challenge to the implementation of effective therapeutic and preventative strategies.
C1 [Yu, Yalu; Xia, Jiaqi; Jiang, Qin] Univ Elect Sci & Technol China, Sch Med, Chengdu 610054, Sichuan, Peoples R China.
   [Jiang, Qin] Univ Elect Sci & Technol, Sichuan Prov Peoples Hosp, Affiliated Hosp, Dept Cardiac Surg, Chengdu 610072, Sichuan, Peoples R China.
   [Jiang, Qin] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Ultrasound Cardiac Electrophysiol & Biomech Key La, Chengdu 610072, Sichuan, Peoples R China.
C3 University of Electronic Science & Technology of China; Sichuan
   Provincial People's Hospital; University of Electronic Science &
   Technology of China; Sichuan Provincial People's Hospital; University of
   Electronic Science & Technology of China
RP Jiang, Q (通讯作者)，Univ Elect Sci & Technol, Sichuan Prov Peoples Hosp, Affiliated Hosp, Dept Cardiac Surg, Chengdu 610072, Sichuan, Peoples R China.; Jiang, Q (通讯作者)，Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Ultrasound Cardiac Electrophysiol & Biomech Key La, Chengdu 610072, Sichuan, Peoples R China.
EM jq349@163.com
FU Huanhua Talent for Discipline Backbone of Sichuan Provincial People's
   Hospital [SY2022017]; Science Fund for Distinguished Young Scholars of
   Sichuan Province [2021JDJQ0041]; National Natural Science and Technology
   Foundation of China [81800274]
FX This work was supported by Huanhua Talent for Discipline Backbone of
   Sichuan Provincial People's Hospital [SY2022017] , Science Fund for
   Distinguished Young Scholars of Sichuan Province [2021JDJQ0041] ,
   National Natural Science and Technology Foundation of China [81800274] .
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NR 84
TC 0
Z9 0
U1 0
U2 6
PU FORUM MULTIMEDIA PUBLISHING, LLC
PI CHARLOTTESVILLE
PA 375 GREENBRIER DR, CHARLOTTESVILLE, VA 22901 USA
SN 1098-3511
EI 1522-6662
J9 HEART SURG FORUM
JI Heart Surg. Forum
PY 2024
VL 27
IS 7
BP E838
EP E846
DI 10.59958/hsf.7617
PG 9
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA D2Y3B
UT WOS:001294888300016
OA gold
DA 2026-07-24
ER

PT J
AU Patel, RRV
   Giaquinto-Cillers, M
   Kotze, J
   Hartnick, RS
   van der Merwe, LW
   Holford, EB
AF Patel, R. R. V.
   Giaquinto-Cillers, M.
   Kotze, J.
   Hartnick, R. S.
   van der Merwe, L. W.
   Holford, E. B.
TI Management of acute complex traumatic wound with a dermal regeneration
   template: Case report
SO SOUTH AFRICAN JOURNAL OF SURGERY
LA English
DT Article
DE reconstruction of lower limbs; dermal regeneration template; complex
   acute wounds; leg trauma; traumatic wounds
ID VACUUM-ASSISTED CLOSURE; NEGATIVE-PRESSURE; SKIN; THERAPY
AB Background: Acute complex traumatic wounds of the lower limbs are usually managed by a combination of multiple debridements, dressing changes, and specialized surgical procedures which may include tissue transfers for the reconstruction of the soft tissue injury. The recovery is lengthy, and the outcome dependent on the initial injury, the surgical procedures undertaken and rehabilitation programs with a multidisciplinary team.
   Methods: A nine-year-old male patient presented to Kimberly Hospital with an extensive soft tissue injury of the leg associated with a tibia fracture caused by a high velocity pedestrian vehicle accident.
   Results: A combination of proper wound care, "homemade" negative pressure wound therapy dressings, reduction of fracture and use of a dermal regeneration template over the fracture site, followed by skin grafting was used to manage the wound.
   Conclusion: The final functional and cosmetic results obtained with the case suggest that the dermal regeneration template may provide a potential alternative for coverage of complex wounds, which might include an open fracture, without the need for complex tissue transfer interventions.
C1 [Patel, R. R. V.; Giaquinto-Cillers, M.; Kotze, J.; Hartnick, R. S.; van der Merwe, L. W.; Holford, E. B.] Kimberley Hosp Complex, Dept Plast & Reconstruct Surg & Burns, Kimberley, Northern Cape P, South Africa.
RP Patel, RRV (通讯作者)，Kimberley Hosp Complex, Dept Plast & Reconstruct Surg & Burns, Kimberley, Northern Cape P, South Africa.
EM ravin.patel.3@gmail.com
CR [Anonymous], ARCH PLAST SURG
   [Anonymous], WOUNDS
   [Anonymous], ISRN ORTHOPEDICS
   [Anonymous], NEXT GENERATION PROD
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   [Anonymous], 38 ANN M AM BURN ASS
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   [Anonymous], COMPLEX WOUND MANAGE
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   Milcheski DA, 2014, PRS-GLOB OPEN, V2, DOI 10.1097/GOX.0000000000000108
   Moiemen NS, 2010, BURNS, V36, P764, DOI 10.1016/j.burns.2010.04.011
   Morozzo U, 2015, INDIAN J SURG, V77, pS1180, DOI 10.1007/s12262-015-1235-6
   Muangman P, 2006, ANN PLAS SURG, V57, P199, DOI 10.1097/01.sap.0000218636.61803.d6
   Nguyen DQA, 2010, BURNS, V36, P23, DOI 10.1016/j.burns.2009.07.011
   Cemile N, 2015, J FOOT ANKLE SURG, V54, P1132, DOI 10.1053/j.jfas.2014.06.014
   Reddy Vikram, 2008, Plast Reconstr Surg, V121, P1, DOI 10.1097/01.prs.0000305928.98611.87
   Rozen WM, 2008, J PLAST RECONSTR AES, V61, P334, DOI 10.1016/j.bjps.2007.01.064
   Shalom A, 2008, ISR MED ASSOC J, V10, P613
   Stiefel D, 2009, J PEDIATR SURG, V44, P575, DOI 10.1016/j.jpedsurg.2008.07.006
   Tufaro AP, 2007, PLAST RECONSTR SURG, V120, P638, DOI 10.1097/01.prs.0000270298.68331.8a
NR 28
TC 0
Z9 0
U1 0
U2 4
PU SA MEDICAL ASSOC
PI PRETORIA
PA BLOCK F CASTLE WALK CORPORATE PARK, NOSSOB STREET, ERASMUSKLOOF EXT3,
   PRETORIA, 0002, SOUTH AFRICA
SN 0038-2361
EI 2078-5151
J9 S AFR J SURG
JI South Afr. J. Surg.
PD NOV
PY 2016
VL 54
IS 4
BP 52
EP 57
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EJ5AJ
UT WOS:000393228600013
PM 28272857
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI Negative-Pressure Wound Therapy
SO JOURNAL OF HAND SURGERY-AMERICAN VOLUME
LA English
DT Editorial Material
NR 0
TC 0
Z9 0
U1 0
U2 1
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0363-5023
J9 J HAND SURG-AM
JI J. Hand Surg.-Am. Vol.
PD SEP
PY 2013
VL 38A
IS 9
BP 1832
EP 1832
PG 1
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 214QD
UT WOS:000324149500042
DA 2026-07-24
ER

PT J
AU Szabo, D
   Turi, S
   Vadász, G
   Gadácsi, M
   Fazekas, G
   Javor, S
   Kasza, G
   Jancsó, G
   Benkö, L
AF Szabo, Dorottya
   Turi, Szamanta
   Vadasz, Gergely
   Gadacsi, Melinda
   Fazekas, Gabor
   Javor, Szaniszlo
   Kasza, Gabor
   Jancso, Gabor
   Benko, Laszlo
TI Prevention of vascular surgical site infections in the groin with
   negative pressure wound therapy
SO ORVOSI HETILAP
LA Hungarian
DT Article
DE negative pressure wound therapy; surgical site infection; groin
AB Introduction: The role of negative pressure wound therapy in the treatment of chronic, difficult-to-heal, infected wounds is becoming increasingly significant. The site most susceptible to infection following vascular surgery is the longitudinal incision wound in the groin. The following factors are predisposing factors for the development of wound infection: diabetes, obesity, previous surgery in the region, lower limb gangrene and ulcers. Objective: The objective of this study was to investigate whether closed incision negative pressure wound therapy reduces the incidence of surgical site infections and wound healing disorders in high-risk patients and whether closed incision negative pressure wound therapy reduces septic graft formation. Method: A total of 38 patients who met at least one of the inclusion criteria (body mass index >30, previous surgery in the same region, wound necrosis) were included in the study. The control group (n = 19) was treated with conventional wound coverage (Cosmopor E). In the closed incision negative pressure wound therapy group (n = 19), the primarily closed wound was covered with polyvinyl alcohol foam (VivanoMed White Foam) intraoperatively, then sealed with an airtight foil. Once the port of the vacuum machine had been connected, wound suction was initiated immediately (continuous suction, 100 mmHg). The duration of treatment was 7 days. Patients were followed up postoperatively at 10, 30, and 60 days. Results: In the control group, 42.1% of patients (n = 8) developed wound healing defects, and 36.8% (n = 7) developed surgical site infection. One patient underwent reoperation for septic graft formation. In the closed incision negative pressure wound therapy group, 31.6% (n = 6) of the patients developed wound healing problem, and 26.3% (n = 5) developed infection; in one case reoperation was performed due to septic graft formation. Conclusion: Regarding the primary endpoint, no notable discrepancies were observed between the examined groups. The results of this study demonstrate that closed incision negative pressure wound therapy may be advantageous over conventional wound care in obese patients and in those who have undergone previous inguinal surgery. A potential avenue for further investigation would be to implement more rigorous inclusion criteria.
C1 [Szabo, Dorottya; Turi, Szamanta; Vadasz, Gergely; Gadacsi, Melinda; Fazekas, Gabor; Javor, Szaniszlo; Kasza, Gabor; Jancso, Gabor; Benko, Laszlo] Pecsi Tudomanyegyet, Klin Kozpont, Altalanos Orvostudomanyi Kar, Ersebeszeti Klin, Pecs, Hungary.
C3 University of Pecs
RP Szabo, D (通讯作者)，Ifjusag Utja 13, H-7624 Pecs, Hungary.
EM dr.szabo.dorottya@pte.hu
CR Aref R, 2022, ORVOSI HETILAP, V163, P271, DOI 10.1556/650.2022.32369
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Barry IP, 2023, VASCULAR, V31, P1128, DOI 10.1177/17085381221111007
   Boll G, 2022, J VASC SURG, V75, P2086, DOI 10.1016/j.jvs.2021.12.070
   Collinge C, 2011, J ORTHOP TRAUMA, V25, P96, DOI 10.1097/BOT.0b013e3181de0134
   Erzsébet SR, 2024, ORVOSI HETILAP, V165, P59, DOI 10.1556/650.2024.32947
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Hajimohammadi Kazem, 2019, Br J Nurs, V28, pS6, DOI [10.12968/bjon.2019.28.12.s6, 10.12968/bjon.2019.28.12.S6]
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   McNulty AK, 2009, WOUND REPAIR REGEN, V17, P192, DOI 10.1111/j.1524-475X.2009.00460.x
   Sabat J, 2016, J VASC SURG, V63, p94S, DOI 10.1016/j.jvs.2016.03.099
   Saleem BR, 2010, AM J SURG, V200, P47, DOI 10.1016/j.amjsurg.2009.05.018
   Sibaja P, 2017, INT J SURG CASE REP, V30, P26, DOI 10.1016/j.ijscr.2016.11.024
NR 15
TC 1
Z9 1
U1 2
U2 2
PU AKADEMIAI KIADO ZRT
PI BUDAPEST
PA BUDAFOKI UT 187-189-A-3, H-1117 BUDAPEST, HUNGARY
SN 0030-6002
EI 1788-6120
J9 ORVOSI HETILAP
JI Orvosi Hetilap
PD OCT
PY 2024
VL 165
IS 42
BP 1652
EP 1658
DI 10.1556/650.2024.33142
PG 7
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA M0H6N
UT WOS:001354445700002
PM 39427290
OA hybrid
DA 2026-07-24
ER

PT J
AU Gibson, K
AF Gibson, K
TI Vacuum-assisted closure
SO AMERICAN JOURNAL OF NURSING
LA English
DT Letter
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0002-936X
J9 AM J NURS
JI Am. J. Nurs.
PD DEC
PY 2004
VL 104
IS 12
BP 16
EP 16
DI 10.1097/00000446-200412000-00008
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 880HV
UT WOS:000225780500012
PM 15621950
DA 2026-07-24
ER

PT J
AU Howell-Taylor, M
   Hall, MG
   Brownlee, WJ
   Taylor, M
AF Howell-Taylor, Melania
   Hall, Macy G., Jr.
   Brownlee, William J., III
   Taylor, Mary
TI Negative pressure wound therapy combined with acoustic pressure wound
   therapy for infected post surgery wounds: A case series
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE acoustic pressure wound therapy; wound care; infection; surgery;
   negative pressure wound therapy
ID LOW-FREQUENCY; ULTRASOUND; NONCONTACT; FOOT
AB Acute infection of surgical incision sites often requires specialized wound care in preparation for surgical closure. Optimal therapy for preparing such wounds for a secondary closure procedure remains uncertain. The authors report wound outcomes after administering acoustic pressure wound therapy in conjunction with negative pressure wound therapy with reticulated open-cell foam dressing changes to assist with bacteria removal from open, infected surgical-incision sites in preparation for secondary surgical closure in three patients. Before incorporating acoustic pressure wound therapy at the authors' facility, the average negative pressure wound therapy with reticulated open-cell foam dressing course prior to secondary surgical closure was 30 days; with its addition, two of three patients underwent successful surgical closure with no postoperative complications after 21 and 14 days, respectively; one patient succumbed to nonwound-related complications before wound closure. Larger, prospective studies are needed to evaluate combining negative pressure wound therapy with reticulated open-cell foam dressing and acoustic pressure wound therapy for infected, acute post surgery wounds.
C1 [Howell-Taylor, Melania; Hall, Macy G., Jr.; Brownlee, William J., III; Taylor, Mary] Specialty Hosp Washington Capitol Hill, Washington, DC USA.
RP Howell-Taylor, M (通讯作者)，Specialty Hosp Washington Capitol Hill, Washington, DC USA.
FU Celleration, Inc; Eden Prairie, Minn; HMP Communications/Ostomy Wound
   Management
FX Support for Sound Evidence is provided by an educational grant from
   Celleration, Inc, Eden Prairie, Minn, to HMP Communications/Ostomy Wound
   Management. Celleration support to authors included medical writing
   and/or statistical support only; study design, patient selection, data
   collection, and metrics to measure wound healing are specific to the
   author The opinions and statements herein are also specific to the
   author and are not necessarily those of Celleration, Inc., OWM, or HMP
   Communications. Please note: these articles are subject to peer review.
   The opinions herein may not be consistent with the labeling for MIST
   Therapy Systems. Patients are selected for educational benefit. Visit
   www.celleration.com for the full package insert. Results may vary.
CR Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   *CELL INC, 2006, MIST THER SYST INSTR
   Gehling ML, 2007, OSTOMY WOUND MANAG, V53, P44
   Kavros SJ, 2007, J AM PODIAT MED ASSN, V97, P95, DOI 10.7547/0970095
   Kent Dea J, 2007, Nursing, V37, P36
   Lewis R, 2001, Health Technol Assess, V5, P1
   Liguori PA, 2008, OSTOMY WOUND MANAG, V54, P50
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stevens DL, 2005, CLIN INFECT DIS, V41, P1373, DOI 10.1086/497143
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   Unger PG, 2008, OSTOMY WOUND MANAG, V54, P57
   Vermeulen H, 2005, BJS-BRIT J SURG, V92, P665, DOI 10.1002/bjs.5055
NR 13
TC 3
Z9 3
U1 0
U2 5
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD SEP
PY 2008
VL 54
IS 9
BP 49
EP 52
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 352CZ
UT WOS:000259474100009
PM 18812625
DA 2026-07-24
ER

PT J
AU Shah, AP
   Kurian, R
   Leung, E
AF Shah, A. P.
   Kurian, R.
   Leung, E.
TI Negative pressure wound therapy in elective stoma reversal surgery:
   results of a UK district general hospital pilot
SO JOURNAL OF HOSPITAL INFECTION
LA English
DT Article
DE Surgical site infection; Negative pressure wound therapy; Stoma reversal
   surgery; Colorectal cancer surgery; Wound management; Infection
   prevention
ID SURGICAL SITE INFECTION
AB The role of negative pressure wound therapy in stoma reversal surgery remains unknown. To evaluate this, a retrospective, non-randomized, single-institution, pilot study was conducted. Surgeon preference determined type of wound closure and application of the single-brand negative wound pressure device. No patient in the intervention group suffered wound complications, but five of the thirty-six patients in the control group suffered surgical site infection-related complications. Primary closure and negative pressure wound therapy use decreases wound complications in stoma reversal surgery, thereby alleviating the wound-management burden in hospitals and in the community. This has cost-saving implications, but further studies are needed. (C) 2019 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
C1 [Shah, A. P.; Kurian, R.; Leung, E.] Cty Hosp, Dept Gen Surg, Stonebow Rd, Hereford HR1 2ER, England.
RP Shah, AP (通讯作者)，Cty Hosp, Dept Gen Surg, Stonebow Rd, Hereford HR1 2ER, England.
EM adarsh.shah3@nhs.net
OI Shah, Adarsh/0000-0002-7004-1751
CR Badia JM, 2017, J HOSP INFECT, V96, P1, DOI 10.1016/j.jhin.2017.03.004
   Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   Gachabayov M, 2019, TECH COLOPROCTOL, V23, P207, DOI 10.1007/s10151-019-01952-9
   Hall C, 2019, J AM COLL SURGEONS, V228, P393, DOI 10.1016/j.jamcollsurg.2018.12.006
   Jenks PJ, 2014, J HOSP INFECT, V86, P24, DOI 10.1016/j.jhin.2013.09.012
   Jones SM, 2005, POSTGRAD MED J, V81, P353, DOI 10.1136/pgmj.2004.026351
   NICE. PICO, NEG PRESS WOUND DRES
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Tanner J, 2009, J HOSP INFECT, V72, P243, DOI 10.1016/j.jhin.2009.03.021
NR 10
TC 2
Z9 2
U1 0
U2 1
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 0195-6701
EI 1532-2939
J9 J HOSP INFECT
JI J. Hosp. Infect.
PD MAR
PY 2020
VL 104
IS 3
BP 332
EP 335
DI 10.1016/j.jhin.2019.11.006
PG 4
WC Public, Environmental & Occupational Health; Infectious Diseases
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Public, Environmental & Occupational Health; Infectious Diseases
GA KR7DA
UT WOS:000517774900017
PM 31738986
DA 2026-07-24
ER

PT J
AU Hung, WC
   Chicco, M
   Huang, TCT
   Cheng, HT
AF Hung, Wei-Chung
   Chicco, Maria
   Huang, Tony Chieh-Ting
   Cheng, Hsu-Tang
TI Reconstruction of an Octogenarian Major Pretibial Degloving Injury
   Utilizing Negative Pressure Wound Therapy and Subsequently Combining
   Fenestrated-Type Artificial Dermis Without Skin Grafting
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Letter
DE major pretibial degloving injury; negative pressure wound therapy;
   artificial dermis
AB Major pretibial degloving injuries are complex wounds, which can be challenging to treat. Despite recent advances in reconstructive options, most of these injuries still require a prolonged healing period and may result in amputation. Few reports have been published on the management of these complex traumatic injuries. In this article, we present a case of an octogenarian, frail patient with a major pretibial degloving injury. Treatment included serial surgical debridements in combination with negative pressure wound therapy aimed at salvaging the avulsed tissue. Subsequently, a fenestrated-type artificial dermis and negative pressure wound therapy were used as combined therapy so as to obtain adequate soft tissue coverage. The patient made an unremarkable recovery and was discharged on day 22 after injury. The wound healed by secondary intention without need for skin grafting.
C1 [Hung, Wei-Chung] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Dept Surg, Taoyuan, Taiwan.
   [Chicco, Maria] Frimley Hlth NHS Fdn Trust, Wexham Pk Hosp, Dept Plast & Reconstruct Surg, Slough, Berks, England.
   [Huang, Tony Chieh-Ting] Mayo Clin, Div Plast & Reconstruct Surg, Rochester, MN USA.
   [Cheng, Hsu-Tang] Asia Univ, Asia Univ Hosp, Coll Med & Hlth Sci, Div Plast & Reconstruct Surg,Dept Surg, 222 Fuxin Rd, Taichung 41354, Taiwan.
   [Cheng, Hsu-Tang] China Med Univ Hosp, Big Data Ctr, Taichung, Taiwan.
C3 Chang Gung University; Chang Gung Memorial Hospital; Mayo Clinic; Asia
   University Taiwan; China Medical University Taiwan; China Medical
   University Hospital - Taiwan
RP Cheng, HT (通讯作者)，Asia Univ, Asia Univ Hosp, Coll Med & Hlth Sci, Div Plast & Reconstruct Surg,Dept Surg, 222 Fuxin Rd, Taichung 41354, Taiwan.; Cheng, HT (通讯作者)，China Med Univ Hosp, Big Data Ctr, Taichung, Taiwan.
EM hsutangcheng@gmail.com
OI Cheng, Hsu-Tang/0000-0003-2835-4372
FU Asia University Hospital Research Program [10851006]; Asia University
   and Asia University Hospital Joint Research Program [ASIA-107-AUH-09];
   Asia University and China Medical University Hospital Joint Research
   Program [ASIA-108-CMUH-23]
FX The author(s) disclosed receipt of the following financial support for
   the research, authorship, and/or publication of this article: This study
   is supported in part by Asia University Hospital Research Program
   (10851006), Asia University and Asia University Hospital Joint Research
   Program (ASIA-107-AUH-09), and Asia University and China Medical
   University Hospital Joint Research Program (ASIA-108-CMUH-23).
CR Brongo S, 2014, CASE REP SURG, V2014, DOI 10.1155/2014/783812
   Kuro A, 2015, J PLAST RECONSTR AES, V68, P286, DOI 10.1016/j.bjps.2014.09.048
   Cemile N, 2015, J FOOT ANKLE SURG, V54, P1132, DOI 10.1053/j.jfas.2014.06.014
   Singh P, 2017, ANN ROY COLL SURG, V99, P637, DOI 10.1308/rcsann.2017.0137
NR 4
TC 0
Z9 1
U1 0
U2 3
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD MAR
PY 2023
VL 22
IS 1
BP 210
EP 212
DI 10.1177/1534734620983251
EA MAR 2021
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 8O4OX
UT WOS:000627084700001
PM 33686897
DA 2026-07-24
ER

PT J
AU Shimono, A
   Sakuma, H
   Watanabe, S
   Kono, H
AF Shimono, Ayano
   Sakuma, Hisashi
   Watanabe, Shiho
   Kono, Hikaru
TI Effective combination of lymphatico-venous anastomosis and negative
   pressure wound therapy for lymphocyst: A Case Study
SO JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
LA English
DT Article
DE lymph node excision; lymphatic cyst; negative pressure wound therapy;
   surgical anastomosis; vaginal cancer
AB Lymphorrhea and lymphocysts are complications that occur after lymph node dissection or biopsy and are difficult to treat. Conventional treatments for lymphocysts are not always effective. For instance, lymphatico-venous anastomosis has a limited treatment efficacy when the cyst wall is thickened, and negative pressure wound therapy is limited by the installation site and longer treatment times. To overcome these individual shortcomings, we aimed to assess whether a combination of both interventions would be effective. In this study, we report the application of a lymphatico-venous anastomosis combined with negative pressure wound therapy for treating bilateral inguinal lymph nodes and pelvic lymph node dissection following treatment of vaginal cancer. Short-term improvements were observed with no recurrence of lymphocysts at 1-year follow-up.
C1 [Shimono, Ayano; Sakuma, Hisashi] Yokohama Municipal Citizens Hosp, Dept Plast & Reconstruct Surg, 56 Okazawa, Yokohama, Kanagawa 2408555, Japan.
   [Watanabe, Shiho] Tokyo Saiseikai Cent Hosp, Dept Plast & Reconstruct Surg, Tokyo, Japan.
   [Kono, Hikaru] Natl Ctr Child Hlth & Dev, Dept Plast & Reconstruct Surg, Tokyo, Japan.
C3 Tokyo Saiseikai Central Hospital; National Center for Child Health &
   Development - Japan
RP Shimono, A (通讯作者)，Yokohama Municipal Citizens Hosp, Dept Plast & Reconstruct Surg, 56 Okazawa, Yokohama, Kanagawa 2408555, Japan.
EM prsshimono@gmail.com
CR FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Greer SE, 2000, BRIT J PLAST SURG, V53, P484, DOI 10.1054/bjps.2000.3360
   Hamed O, 2008, J VASC SURG, V48, P1520, DOI 10.1016/j.jvs.2008.07.059
   Ito Y, 2012, NIHON HINYOKIKA GAKK, V103, P22
   Iwamoto T, 2008, APPL LYMPHATIC VENOU, V22, P80
   Koshima I, 2012, JPN J UROL SURG, V25, P1303
   Mitate E, 2016, Journal of Japanese Society of Oral Oncology, V28, P155, DOI 10.5843/jsot.28.155
   Tauber R, 2013, J PLAST RECONSTR AES, V66, P390, DOI 10.1016/j.bjps.2012.09.030
   Todokoro T, 2013, GYNECOL ONCOL, V128, P209, DOI 10.1016/j.ygyno.2012.11.014
   Yuan Y, 2019, J SURG RES, V235, P329, DOI 10.1016/j.jss.2018.09.065
NR 10
TC 1
Z9 2
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1341-8076
EI 1447-0756
J9 J OBSTET GYNAECOL RE
JI J. Obstet. Gynaecol. Res.
PD JUL
PY 2020
VL 46
IS 7
BP 1224
EP 1228
DI 10.1111/jog.14300
EA MAY 2020
PG 5
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA ME2NK
UT WOS:000535853500001
PM 32464690
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Fujisawa, K
   Miyamoto, S
   Saito, Y
   Okazaki, M
AF Fujisawa, Kou
   Miyamoto, Shimpei
   Saito, Yuki
   Okazaki, Mutsumi
TI Negative Pressure Wound Therapy with Instillation and Dwell Time for
   Pharyngocutaneous Fistula
SO LARYNGOSCOPE
LA English
DT Article
DE head and neck reconstruction; negative pressure wound therapy with
   instillation and dwell time; pharyngocutaneous fistula
AB Pharyngocutaneous fistula is a critical complication of head and neck cancer reconstruction and it is often difficult to manage. We herein report two cases of pharyngocutaneous fistulas that developed after oropharyngeal reconstruction and were successfully treated with negative pressure wound therapy with instillation and dwell time (NPWTi-d), an advanced form of traditional NPWT. NPWTi-d may be a useful nonsurgical treatment for pharyngocutaneous fistula. Laryngoscope, 2024
   Pharyngocutaneous fistula is a critical complication of head and neck cancer reconstruction and it is often difficult to manage. We herein report two cases of pharyngocutaneous fistulas that developed after oropharyngeal reconstruction and were successfully treated with negative pressure wound therapy with instillation and dwell time (NPWTi-d), an advanced form of traditional NPWT. NPWTi-d may be a useful nonsurgical treatment for pharyngocutaneous fistula. image
C1 [Fujisawa, Kou; Miyamoto, Shimpei; Okazaki, Mutsumi] Univ Tokyo, Dept Plast & Reconstruct Surg, 7-3-1 Hongo,Bunkyo Ku, Tokyo 1138655, Japan.
   [Saito, Yuki] Univ Tokyo, Dept Otolaryngol & Head & Neck Surg, Tokyo, Japan.
C3 University of Tokyo; University of Tokyo
RP Fujisawa, K (通讯作者)，Univ Tokyo, Dept Plast & Reconstruct Surg, 7-3-1 Hongo,Bunkyo Ku, Tokyo 1138655, Japan.
EM kofujisawa@gmail.com
RI ; Okazaki, Mutsumi/ISU-1959-2023; Fujisawa, Kou/AIB-5993-2022
OI Fujisawa, Kou/0000-0003-3601-7739; 
CR Asher SA, 2014, JAMA FACIAL PLAST SU, V16, P120, DOI 10.1001/jamafacial.2013.2163
   De Pellegrin L, 2023, INT WOUND J, V20, P2402, DOI 10.1111/iwj.14072
   Liebman RM, 2023, SEMIN PLAST SURG, V37, P9, DOI 10.1055/s-0042-1759562
   Migacz E, 2018, NEG PRESS WOUND THER, V5, P14, DOI 10.18487/npwtj.v5i2.40
   Steinbichler TB, 2021, HEAD NECK-J SCI SPEC, V43, P2377, DOI 10.1002/hed.26684
NR 5
TC 3
Z9 4
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0023-852X
EI 1531-4995
J9 LARYNGOSCOPE
JI Laryngoscope
PD NOV
PY 2024
VL 134
IS 11
BP 4573
EP 4576
DI 10.1002/lary.31549
EA JUN 2024
PG 4
WC Medicine, Research & Experimental; Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Otorhinolaryngology
GA J8A7V
UT WOS:001236216500001
PM 38822695
DA 2026-07-24
ER

PT J
AU Liu, JY
   Hu, F
   Tang, JT
   Tang, SJ
   Xia, K
   Wu, S
   Yin, CQ
   Wang, SH
   He, QY
   Xie, HQ
   Zhou, JD
AF Liu, Jinyan
   Hu, Feng
   Tang, Jintian
   Tang, Shijie
   Xia, Kun
   Wu, Song
   Yin, Chaoqi
   Wang, Shaohua
   He, Quanyong
   Xie, Huiqing
   Zhou, Jianda
TI Homemade-device-induced negative pressure promotes wound healing more
   efficiently than VSD-induced positive pressure by regulating
   inflammation, proliferation and remodeling
SO INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
LA English
DT Article
DE wound healing; negative pressure; cell infiltration; positive pressure;
   vacuum sealing drainage; growth factor; inflammation; extracellular
   matrix
ID VACUUM-ASSISTED CLOSURE; STEM-CELLS; THERAPY; STATE
AB Vacuum sealing drainage (VSD) is an effective technique used to promote wound healing. However, recent studies have shown that it exerts positive pressure (PP) rather than negative pressure (NP) on skin. In this study, we created a homemade device that could maintain NP on the wound, and compared the therapeutic effects of VSD-induced PP to those of our home-made device which induced NP on wound healing. The NP induced by our device required less time for wound healing and decreased the wound area more efficiently than the PP induced by VSD. NP and PP both promoted the inflammatory response by upregulating neutrophil infiltration and interleukin (IL)-1 expression, and downregulating IL-10 expression. Higher levels of epidermal growth factor (EGF), transforming growth factor (TGF)- and platelet-derived growth factor (PDGF), and lower levels of basic fibroblast growth factor (bFGF) were observed in the wound tissue treated with NP compared to the wound tissue exposed to PP. Proliferation in the wound tissue exposed to NP on day 10 was significantly higher than that in wound tissue exposed to PP. NP generated more fibroblasts, keratinized stratified epithelium, and less epithelia with stemness than PP. The levels of ccollagen I and III were both decreased in both the NP and PP groups. NP induced a statistically significant increase in the expression of fibronectin (FN) on days 3 and 10 compared to PP. Furthermore, the level of matrix metalloproteinase (MMP)-13 increased in the NP group, but decreased in the PP group on day 3. NP also induced a decrease in the levels of tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 during the early stages of wound healing, which was significantly different from the increasing effect of PP on TIMP-1 and TIMP-2 levels at the corresponding time points. On the whole, our data indicate that our homemade device which induced NP, was more efficient than VSD-induced PP on wound healing by regulating inflammation, secretion, proliferation and the distribution of different cells in wound tissue.
C1 [Liu, Jinyan] Cent S Univ, Xiangya Hosp 1, Dept Nucl Med, Changsha 410008, Hunan, Peoples R China.
   [Hu, Feng; Yin, Chaoqi; Wang, Shaohua; He, Quanyong; Zhou, Jianda] Cent S Univ, Xiangya Hosp 3, Dept Plast Surg, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.
   [Tang, Jintian] Tsinghua Univ, Inst Med Phys & Engn, Beijing 100084, Peoples R China.
   [Tang, Shijie] Shantou Univ, Coll Med, Affiliated Hosp 2, Cleft Lip & Palate Treatment Ctr, Shantou 515041, Guangdong, Peoples R China.
   [Xia, Kun] Cent S Univ, Key Lab Med Informat Res, Changsha, Hunan, Peoples R China.
   [Wu, Song] Cent S Univ, Xiangya Hosp 3, Dept Orthoped, Changsha 410013, Hunan, Peoples R China.
   [Xie, Huiqing] Cent S Univ, Xiangya Hosp 3, Dept Rehabil Med, Changsha 410013, Hunan, Peoples R China.
C3 Central South University; Central South University; Tsinghua University;
   Shantou University; Central South University; Central South University;
   Central South University
RP Zhou, JD (通讯作者)，Cent S Univ, Xiangya Hosp 3, Dept Plast Surg, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.
EM zhoujianda_csu@163.com
FU Key Projects of the Fund of Science and Technology Department of Hunan
   Province [2014SK2018]; Scientific Research Fund of the Health Department
   of Hunan Province [132013-026]
FX This study was supported by the Key Projects of the Fund of Science and
   Technology Department of Hunan Province (2014SK2018) and the Scientific
   Research Fund of the Health Department of Hunan Province (132013-026).
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NR 27
TC 14
Z9 23
U1 1
U2 18
PU SPANDIDOS PUBL LTD
PI ATHENS
PA POB 18179, ATHENS, 116 10, GREECE
SN 1107-3756
EI 1791-244X
J9 INT J MOL MED
JI Int. J. Mol. Med.
PD APR
PY 2017
VL 39
IS 4
BP 879
EP 888
DI 10.3892/ijmm.2017.2919
PG 10
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA ES9XK
UT WOS:000399915100012
PM 28290607
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Nguyen, DC
   Buettner, AM
   Dousa, KM
AF Nguyen, David C.
   Buettner, Angel M.
   Dousa, Khalid M.
TI Case Commentary: Another prong of attack? Topical antibiotic
   instillation with negative pressure wound therapy for nontuberculous
   mycobacterial skin and soft tissue infections
SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
LA English
DT Article
DE Mycobacterium; skin and soft tissue Infection; negative pressure wound
   therapy; wound
AB Nontuberculous mycobacteria (NTM) skin infections remain therapeutically challenging. Given the diversity in infections, host responses, and antimicrobials, clinical guidelines are often built on case series and observational studies. In this commentary, we respond to a paper by Stemkens et al. that introduces an emerging strategy: adjunctive negative pressure wound therapy with instillation and dwell time combined with topical antibiotics for refractory NTM skin and soft tissue infections. We delve into the primary considerations surrounding this innovative approach.
C1 [Nguyen, David C.] Rush Med Coll, Div Pediat Infect Dis, Dept Pediat, Chicago, IL USA.
   [Nguyen, David C.] Rush Med Coll, Div Infect Dis, Dept Internal Med, Chicago, IL USA.
   [Buettner, Angel M.] Advocate Aurora Healthcare Syst, Dept Hyperbar Med & Wound Care, Sheboygan, WI USA.
   [Dousa, Khalid M.] Case Western Reserve Univ, Dept Med, Cleveland, OH 44106 USA.
   [Dousa, Khalid M.] Vet Affairs Northeast Ohio Healthcare Syst, Cleveland, OH 44106 USA.
C3 Rush University; Rush University; University System of Ohio; Case
   Western Reserve University
RP Dousa, KM (通讯作者)，Case Western Reserve Univ, Dept Med, Cleveland, OH 44106 USA.; Dousa, KM (通讯作者)，Vet Affairs Northeast Ohio Healthcare Syst, Cleveland, OH 44106 USA.
EM kxd231@case.edu
OI Nguyen, David/0000-0001-5738-2976; Dousa, Khalid M/0000-0003-3272-7231
CR Bovill E, 2008, INT WOUND J, V5, P511, DOI 10.1111/j.1742-481X.2008.00437.x
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   van Wijk F, 2020, ANTIMICROB AGENTS CH, V64, DOI 10.1128/AAC.01203-19
NR 14
TC 1
Z9 2
U1 0
U2 1
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0066-4804
EI 1098-6596
J9 ANTIMICROB AGENTS CH
JI Antimicrob. Agents Chemother.
PD DEC
PY 2023
VL 67
IS 12
DI 10.1128/aac.01048-23
EA NOV 2023
PG 3
WC Microbiology; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Microbiology; Pharmacology & Pharmacy
GA 6DF8D
UT WOS:001124422800003
PM 38014943
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Mochizuki, T
   Ikari, K
   Hiroshima, R
   Takaoka, H
   Kawakami, K
   Koenuma, N
   Ishibashi, M
   Momohara, S
AF Mochizuki, Takeshi
   Ikari, Katsunori
   Hiroshima, Ryo
   Takaoka, Hiromitsu
   Kawakami, Kosei
   Koenuma, Naoko
   Ishibashi, Mina
   Momohara, Shigeki
TI Negative pressure wound therapy and skin grafting for necrotizing
   fasciitis in a patient with rheumatoid arthritis treated with abatacept:
   A case report
SO MODERN RHEUMATOLOGY
LA English
DT Article
DE Abatacept; Necrotizing fasciitis; Negative pressure wound therapy;
   Rheumatoid arthritis
ID INADEQUATE RESPONSE; LONG-TERM; TOCILIZUMAB; SAFETY; TRIAL
AB Herein, we present a case of necrotizing fasciitis (NF) in a patient with rheumatoid arthritis (RA) treated with abatacept. Cultures of the patient's leg effusion revealed group A Streptococcus. Treatment included antibiological drugs, repeat debridement, negative pressure wound therapy (NPWT), and skin grafting. This case highlights the need for suspicion of severe bacterial infection for early diagnosis and effective treatment. NF with RA can be treated effectively with repeat debridement and NPWT.
C1 [Mochizuki, Takeshi; Hiroshima, Ryo; Takaoka, Hiromitsu; Kawakami, Kosei; Koenuma, Naoko; Ishibashi, Mina] Kamagaya Gen Hosp, Dept Orthoped Surg, 929-6 Hatsutomi, Kamagaya, Chiba 2730121, Japan.
   [Ikari, Katsunori; Momohara, Shigeki] Tokyo Womens Med Univ, Inst Rheumatol, Tokyo, Japan.
C3 Tokyo Women's Medical University
RP Mochizuki, T (通讯作者)，Kamagaya Gen Hosp, Dept Orthoped Surg, 929-6 Hatsutomi, Kamagaya, Chiba 2730121, Japan.
EM twmutamo@gmail.com
FU AbbVie, Inc.; Asahi Kasei Pharma Corp.; Astellas Pharma Inc.;
   Bristol-Myers Squibb Co.; Chugai Pharmaceutical Co.; Eisai Co., Ltd.;
   Hisamitsu Pharmaceutical Co. Inc.; Janssen Pharmaceutical K. K.; Kaken
   Pharmaceutical Co. Ltd.; Mitsubishi Tanabe Pharma Co.; Santen
   Pharmaceutical Co., Ltd.; Taisho Toyama Pharmaceutical Co. Ltd.; Daiichi
   Sankyo Co., Ltd.; Nakashima Medical Co., Ltd.; Takeda Pharmaceutical
   Co., Ltd.
FX T. M. received honorarium for the lecture from AbbVie, Inc., Asahi Kasei
   Pharma Corp., Bristol-Myers Squibb Co., Chugai Pharmaceutical Co.,
   Daiichi Sankyo Co., Ltd., Eisai Co., Ltd., Eli Lilly Japan Co., Janssen
   Pharmaceutical K.K., Mitsubishi Tanabe Pharma Co., and Takeda
   Pharmaceutical Co., Ltd. K. Y. received honorarium for the lecture from
   Janssen Pharmaceutical K. K., Mitsubishi Tanabe Pharma Co., Santen
   Pharmaceutical Co., Ltd. and Takeda Pharmaceutical Co., Ltd. K. I.
   received honorarium for the lecture and/or unrestricted research grants
   from AbbVie, Inc., Asahi Kasei Pharma Corp., Astellas Pharma Inc.,
   Bristol-Myers Squibb Co., Chugai Pharmaceutical Co., Eisai Co., Ltd.
   Hisamitsu Pharmaceutical Co. Inc., Janssen Pharmaceutical K. K., Kaken
   Pharmaceutical Co. Ltd., Mitsubishi Tanabe Pharma Co., Santen
   Pharmaceutical Co., Ltd., Taisho Toyama Pharmaceutical Co. Ltd. and
   Takeda Pharmaceutical Co., Ltd. S. M. received honorarium for the
   lecture and/or unrestricted research grants from AbbVie, Inc., Asahi
   Kasei Pharma Corp., Bristol-Myers Squibb Co., Chugai Pharmaceutical Co.,
   Daiichi Sankyo Co., Ltd., Eisai Co., Ltd., Mitsubishi Tanabe Pharma Co.,
   Nakashima Medical Co., Ltd., Santen Pharmaceutical Co., Ltd., Taisho
   Toyama Pharmaceutical Co. Ltd. and Takeda Pharmaceutical Co., Ltd. The
   other authors declare that they have no conflicts of interest.
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   Cheung Jason P. Y., 2009, Hong Kong Medical Journal, V15, P44
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NR 15
TC 0
Z9 1
U1 0
U2 3
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND
SN 1439-7595
EI 1439-7609
J9 MOD RHEUMATOL
JI Mod. Rheumatol.
PY 2018
VL 28
IS 2
BP 358
EP 360
DI 10.3109/14397595.2015.1106645
PG 3
WC Rheumatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Rheumatology
GA FY6FG
UT WOS:000426937600023
PM 26457807
DA 2026-07-24
ER

PT J
AU Garas, G
   Ifeacho, S
   Millard, R
   Tolley, N
AF Garas, G.
   Ifeacho, S.
   Millard, R.
   Tolley, N.
TI Melioidosis and the vacuum-assisted closure device: a rare cause of a
   discharging neck wound, and a new approach to management
SO JOURNAL OF LARYNGOLOGY AND OTOLOGY
LA English
DT Article
DE Melioidosis; Burkholderia Pseudomallei; Vacuum Pump
ID BURKHOLDERIA-PSEUDOMALLEI; STERNAL WOUNDS; AUSTRALIA; SYSTEM;
   EPIDEMIOLOGY; HEAD; MASS
AB Objective: We report a case of melioidosis presenting as a discharging neck abscess, and we describe the use of a vacuum-assisted closure device in its management.
   Method: We report the case of a 44-year-old, Afro-Caribbean woman with melioidosis. We also present the results of a literature search using the search terms 'melioidosis', 'Burkholderia pseudomallei' and 'vacuum-assisted closure device'.
   Results: Microbiological analysis identified the causative organism as being the bacterium Burkholderia pseudomallei, and its antimicrobial sensitivities to imipenem and ciprofloxacin. A vacuum-assisted closure device was used to manage the patient's melioidosis of the neck; we believe this is the first report of such treatment.
   Conclusions: Melioidosis is rare in the UK and western world; however, exposure can occur during travel to endemic areas. We therefore draw attention to this infection as part of the differential diagnosis of a neck abscess. We propose the use of vacuum-assisted closure devices as useful adjuncts to the management of discharging neck wounds.
C1 [Garas, G.; Ifeacho, S.; Millard, R.; Tolley, N.] St Marys Hosp, Dept Otorhinolaryngol Head & Neck Surg, London W2 1NY, England.
C3 Imperial College London
RP Garas, G (通讯作者)，St Marys Hosp, Dept Otorhinolaryngol Head & Neck Surg, Praed St, London W2 1NY, England.
EM garas_george@yahoo.com
RI Garas, George/AAC-1968-2019
OI Garas, George/0000-0001-7468-3287
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NR 32
TC 8
Z9 9
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA EDINBURGH BLDG, SHAFTESBURY RD, CB2 8RU CAMBRIDGE, ENGLAND
SN 0022-2151
EI 1748-5460
J9 J LARYNGOL OTOL
JI J. Laryngol. Otol.
PD SEP
PY 2010
VL 124
IS 9
BP 1021
EP 1024
DI 10.1017/S0022215110000381
PG 4
WC Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology
GA 655GV
UT WOS:000282237900018
PM 20219147
DA 2026-07-24
ER

PT J
AU Al-Benna, S
AF Al-Benna, Sammy
TI Economical negative pressure wound therapy
SO ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND
LA English
DT Editorial Material
C1 Ruhr Univ Bochum, BG Univ Hosp Bergmannsheil, Bochum, Germany.
C3 Ruhr University Bochum
RP Al-Benna, S (通讯作者)，Ruhr Univ Bochum, BG Univ Hosp Bergmannsheil, Univ Str 150, Bochum, Germany.
EM sammy.al-benna@ruhr-uni-bochum.de
RI Al-Benna, Sammy/AAG-1463-2019
OI Al-Benna, Sammy/0000-0003-4079-9286
CR Al-Benna S, 2008, PLAST RECONSTR SURG, V121, P681, DOI 10.1097/01.prs.0000298544.24607.ca
   Al-Benna S, 2010, OSTOMY WOUND MANAG, V56, P48
NR 2
TC 4
Z9 4
U1 0
U2 3
PU ROYAL COLL SURGEONS ENGLAND
PI LONDON
PA 35-43 LINCOLN'S INN FIELDS, LONDON WC2A 3PN, ENGLAND
SN 0035-8843
J9 ANN ROY COLL SURG
JI Ann. R. Coll. Surg. Engl.
PD APR
PY 2012
VL 94
IS 3
BP 214
EP 214
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 931PK
UT WOS:000303231600026
PM 22507736
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Wedemeyer, J
   Helfritz, FA
   Brangewitz, M
   Winkler, M
   Manns, MP
   Schneider, A
AF Wedemeyer, J.
   Helfritz, F. A.
   Brangewitz, M.
   Winkler, M.
   Manns, M. P.
   Schneider, A.
TI Endoscopic Vacuum Assisted Closure for Intestinal Leakages
SO ENDOSKOPIE HEUTE
LA German
DT Article
DE anastomotic leakage; stent; endoscopic vacuum assisted closure
ID ESOPHAGEAL ANASTOMOTIC LEAKS; EXPANDING PLASTIC STENTS; PRESSURE WOUND
   THERAPY; GASTRIC-CARCINOMA; PERFORATIONS; MULTICENTER; EXPERIENCE;
   MANAGEMENT; SURGERY
AB Anastomotic leakage in the upper and lower intestinal tract is associated with high morbidity and mortality. Endoscopic vacuum assisted closure (E-V.A.C.) is a new innovative endoscopic therapeutic option. E-V.A.C. transfers the positive effects of vacuum assisted closure (V.A.C.) on infected cutaneous Wounds to infected cavities that can only be reached endoscopically. For the treatment of rectal insufficiency, a commercially available vacuum system (Endosponge (R)) is available. In the upper gastrointestinal tract the method has been applied successfully for the treatment of intrathoracic anastomotic leakages. E-V.A.C. might be an important alternative to stent placement in intrathoracic anastomotic leakage. Additional indications for the application of E-V.A.C. are expected to be developed within the near future.
C1 [Wedemeyer, J.; Brangewitz, M.; Manns, M. P.; Schneider, A.] Hannover Med Sch, Klin Gastroenterol Hepatol & Endokrinol, D-30625 Hannover, Germany.
   [Helfritz, F. A.; Winkler, M.] Hannover Med Sch, Klin Allgemein Viszeral & Transplantat Chirurg, D-30625 Hannover, Germany.
C3 Hannover Medical School; Hannover Medical School
RP Wedemeyer, J (通讯作者)，Hannover Med Sch, Klin Gastroenterol Hepatol & Endokrinol, Carl Neuberg Str 1, D-30625 Hannover, Germany.
EM wedemeyer.jochen@mh-hannover.de
RI Manns, Michael/AFG-3063-2022
CR Choudhury SH, 2001, AM J ROENTGENOL, V176, P161, DOI 10.2214/ajr.176.1.1760161
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NR 28
TC 1
Z9 1
U1 0
U2 2
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0933-811X
EI 1439-2577
J9 ENDOSKOPIE HEUTE
JI Endoskopie Heute
PD MAR
PY 2010
VL 23
IS 1
BP 41
EP 45
DI 10.1055/s-0030-1247247
PG 5
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 571WF
UT WOS:000275785900009
DA 2026-07-24
ER

PT J
AU Ailaney, N
   Johns, WL
   Golladay, GJ
   Strong, B
   Kalore, N
AF Ailaney, Nikhil
   Johns, William L.
   Golladay, Gregory J.
   Strong, Benjamin
   Kalore, Niraj, V
TI Closed Incision Negative Pressure Wound Therapy for Elective Hip and
   Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized
   Controlled Trials
SO JOURNAL OF ARTHROPLASTY
LA English
DT Review
DE closed incision negative pressure wound; therapy; surgical site
   infection; wound complication; total knee arthroplasty; total hip
   arthroplasty
ID VACUUM-ASSISTED CLOSURE; MICROVASCULAR BLOOD-FLOW; COMPLICATIONS;
   DRESSINGS; DRAINAGE; SURGERY; MANAGEMENT; FRACTURES; INFECTION
AB Background: Persistent wound drainage after total joint arthroplasty (TJA) increases the risk of surgical site infections (SSIs). Closed incision negative pressure wound therapy (ciNPWT) decreases infections in traumatic wounds, but evidence for its use after elective TJA is limited. The purpose of this meta-analysis of level I studies is to determine the effect of ciNPWT on risk of SSI and wound complications following TJA.
   Methods: MEDLINE, EMBASE, CINAHL, and Cochrane Library were searched for randomized controlled trials comparing ciNPWT vs standard dressings after total hip (THA) and total knee arthroplasty (TKA). Studies exclusively involving THA for femoral neck fractures were excluded. Risk of SSI and noninfectious wound complications (blisters, seroma, hematoma, persistent drainage, dehiscence, and wound edge necrosis) following TJA were analyzed.
   Results: SSI risk was lower with ciNPWT compared to standard dressings (3.4% vs 7%; relative risk [RR] 0.48, P = .007), specifically in revision THA and TKA (4.1% vs 10.5%; RR 0.41, P = .03). ciNPWT increased the noninfectious complication risk after primary TKA (RR 4.71, P<.0001), especially causing wound blistering (RR 12.66, P<.0001). ciNPWT decreased hospital length of stay by 0.73 days (P = .04) and reoperation rate (RR 0.28, P = .01).
   Conclusion: ciNPWT decreases SSI risk compared to standard dressings after revision TJA, but not primary TJA. ciNPWT is associated with >12-fold increased risk of wound blistering after primary TKA. ciNPWT plays a role in revision TJA management, but additional randomized controlled trials with uniform wound assessment methods must be performed to sufficiently power findings and draw conclusions on the use of ciNPWT after primary TJA. (C) 2020 Elsevier Inc. All rights reserved.
C1 [Ailaney, Nikhil; Johns, William L.] Virginia Commonwealth Univ, Sch Med, Dept Orthopaed Surg, 1200 East Broad St,9th Floor, Richmond, VA 23298 USA.
   [Golladay, Gregory J.; Strong, Benjamin; Kalore, Niraj, V] Virginia Commonwealth Univ Hlth, Dept Orthopaed Surg, Richmond, VA USA.
C3 Virginia Commonwealth University
RP Ailaney, N (通讯作者)，Virginia Commonwealth Univ, Sch Med, Dept Orthopaed Surg, 1200 East Broad St,9th Floor, Richmond, VA 23298 USA.
RI Kalore, Niraj/J-1828-2012; Golladay, Gregory/AAF-5244-2020
OI Kalore, Niraj/0000-0003-3452-418X; Ailaney, Nikhil/0000-0003-2309-6909; 
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NR 43
TC 34
Z9 44
U1 0
U2 6
PU CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS
PI PHILADELPHIA
PA CURTIS CENTER, INDEPENDENCE SQUARE WEST, PHILADELPHIA, PA 19106-3399 USA
SN 0883-5403
EI 1532-8406
J9 J ARTHROPLASTY
JI J. Arthroplast.
PD JUL
PY 2021
VL 36
IS 7
BP 2402
EP 2411
DI 10.1016/j.arth.2020.11.039
EA JUN 2021
PG 10
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA SR5II
UT WOS:000661074600033
PM 33358608
DA 2026-07-24
ER

PT J
AU Frenda, G
   Baker, L
   Zhang, YM
   Nessim, C
AF Frenda, Giuseppe
   Baker, Laura
   Zhang, Yimeng
   Nessim, Carolyn
TI Role of a skin bridge incision and prophylactic incisional
   negative-pressure wound therapy in the prevention of surgical site
   infection after inguinal lymph node dissection
SO CANADIAN JOURNAL OF SURGERY
LA English
DT Article; Proceedings Paper
CT Annual Meeting of the Society-for-Surgical-Oncology (SSO) /
   International Conference on Surgical Cancer Care
CY AUG 17-18, 2020
CL ELECTR NETWORK
SP Soc Surg Oncol
ID VACUUM-ASSISTED CLOSURE; RISK-FACTORS; MELANOMA; COMPLICATIONS;
   MORBIDITY; GUIDELINE; OUTCOMES; MODEL; STATE
AB Background:Modification of the surgical technique to a 2-incision technique with skin bridge from the traditional lazy S (LS) incision, as well as use of prophylactic incisional negative-pressure wound therapy (iNPWT), are theorized to reduce the risk of surgical site infection (SSI) after inguinal lymph node dissection (ILND). We sought to investigate the role of a perioperative ILND bundle on adverse events after ILND and lymph node harvest. Methods:We performed a retrospective review of patients who underwent ILND before and after implementation of the ILND bundle (September 2016) at 1 centre in southeastern Ontario between 2013 and 2018. The ILND bundle included a skin bridge incision, running subcuticular skin closure and NPWT. Previously, an LS incision was used, with stapled skin closure and conventional dressing. Development of SSI was the primary outcome, and dehiscence and seroma and hematoma formation were secondary outcomes. We estimated the associations using multivariable logistic regression. Results:Thirty-four ILNDs in 33 patients were included, 15 in the LS incision group and 19 in the perioperative bundle group. The baseline demographic characteristics of the 2 groups were similar. The perioperative bundle was associated with a reduction in the SSI rate (11 [73%] v. 6 [32%], p = 0.02) and elimination of wound dehiscence (0 [0%] v. 5 [33%], p = 0.006). On multivariable logistic regression, it was associated with a 5.9-fold reduction in the SSI rate (odds ratio 0.17, 95% confidence interval 0.03-0.74). Conclusion:The results suggest a decrease in SSI rates with use of a perioperative bundle compared to the LS incision and a standard dressing. Randomized controlled trials are required to better understand the associations among the skin bridge incision, iNPWT and SSI.
C1 [Frenda, Giuseppe] McGill Univ, Div Gen Surg, Montreal, PQ, Canada.
   [Baker, Laura; Zhang, Yimeng; Nessim, Carolyn] Univ Ottawa, Ottawa Hosp Res Inst, Div Gen Surg, Ottawa, ON, Canada.
   [Nessim, Carolyn] Univ Ottawa, Ottawa Hosp, Canc Therapeut Program, OHRI Surg Oncol, Room CCW 1617d,POB 202,501 Smyth Rd, Ottawa, ON K1H 8L6, Canada.
C3 McGill University; University of Ottawa; Ottawa Hospital Research
   Institute; University of Ottawa; Ottawa Hospital Research Institute
RP Nessim, C (通讯作者)，Univ Ottawa, Ottawa Hosp, Canc Therapeut Program, OHRI Surg Oncol, Room CCW 1617d,POB 202,501 Smyth Rd, Ottawa, ON K1H 8L6, Canada.
EM cnessim@toh.ca
RI Nessim, Carolyn/AAH-8293-2019
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NR 37
TC 1
Z9 1
U1 0
U2 5
PU CMA-CANADIAN MEDICAL ASSOC
PI OTTAWA
PA 1867 ALTA VISTA DR, OTTAWA, ONTARIO K1G 5W8, CANADA
SN 0008-428X
EI 1488-2310
J9 CAN J SURG
JI Can. J. Surg.
PD OCT 20
PY 2022
VL 65
IS 5
BP E688
EP E694
DI 10.1503/cjs.005621
EA DEC 2022
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 5R5SN
UT WOS:000874570300001
PM 36265898
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Goda, H
   Hamakawa, T
   Nakashiro, KI
AF Goda, Hiroyuki
   Hamakawa, Tomohiro
   Nakashiro, Koh-Ichi
TI Successful management of an orocutaneous fistula and exposed mandibular
   plate with the vacuum-assisted closure system: A case report
SO EXPERIMENTAL AND THERAPEUTIC MEDICINE
LA English
DT Article
DE vacuum-assisted closure; mandibular plate exposure; orocutaneous fistula
ID WOUND CONTROL; THERAPY; DEVICE
AB Orocutaneous fistulas are one of the most problematic postoperative complications after oral cancer surgery. Notably, in patients with mandibular plate exposure it is necessary to remove the plate. However, it takes longer for these patients to achieve complete fistula closure. The present report described an 84-year-old man with a postoperative orocutaneous fistula and exposed mandibular plate who was treated with the vacuum-assisted closure system. This system protects the wound from contamination while the negative pressure prevents tissue fluid retention, promotes blood flow, facilitates granulation tissue formation and decreases the bacterial cell count. Vacuum-assisted closure was successful in the present case, and complete fistula closure took 20 days. Additionally, there was no evidence of recurrence over the 11-month follow-up.
C1 [Goda, Hiroyuki; Hamakawa, Tomohiro; Nakashiro, Koh-Ichi] Ehime Univ, Grad Sch Med, Dept Oral & Maxillofacial Surg, 454 Shitsukawa, Toon, Ehime 7910204, Japan.
C3 Ehime University
RP Goda, H (通讯作者)，Ehime Univ, Grad Sch Med, Dept Oral & Maxillofacial Surg, 454 Shitsukawa, Toon, Ehime 7910204, Japan.
EM hiro9832@m.ehime-u.ac.jp
RI Nakashiro, Koh-ichi/AAV-6317-2020
OI Nakashiro, Koh-ichi/0000-0002-9975-902X
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NR 14
TC 4
Z9 4
U1 0
U2 1
PU SPANDIDOS PUBL LTD
PI ATHENS
PA POB 18179, ATHENS, 116 10, GREECE
SN 1792-0981
EI 1792-1015
J9 EXP THER MED
JI Exp. Ther. Med.
PD DEC
PY 2018
VL 16
IS 6
BP 5315
EP 5317
DI 10.3892/etm.2018.6869
PG 3
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA HC9UF
UT WOS:000452151700139
PM 30542489
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Seidel, D
   Storck, M
   Lawall, H
   Wozniak, G
   Mauckner, P
   Hochlenert, D
   Wetzel-Roth, W
   Sondern, K
   Hahn, M
   Rothenaicher, G
   Krönert, T
   Zink, K
   Neugebauer, E
AF Seidel, Doerthe
   Storck, Martin
   Lawall, Holger
   Wozniak, Gernold
   Mauckner, Peter
   Hochlenert, Dirk
   Wetzel-Roth, Walter
   Sondern, Klemens
   Hahn, Matthias
   Rothenaicher, Gerhard
   Kroenert, Thomas
   Zink, Karl
   Neugebauer, Edmund
TI Negative pressure wound therapy compared with standard moist wound care
   on diabetic foot ulcers in real-life clinical practice: results of the
   German DiaFu-RCT
SO BMJ OPEN
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MULTICENTER; AMPUTATION
AB Objectives The aim of the DiaFu study was to evaluate effectiveness and safety of negative pressure wound therapy (NPWT) in patients with diabetic foot wounds in clinical practice.
   Design In this controlled clinical superiority trial with blinded outcome assessment patients were randomised in a 1:1 ratio stratified by study site and ulcer severity grade using a web-based-tool.
   Setting This German national study was conducted in 40 surgical and internal medicine inpatient and outpatient facilities specialised in diabetes foot care.
   Participants 368 patients were randomised and 345 participants were included in the modified intention-to-treat (ITT) population. Adult patients suffering from a diabetic foot ulcer at least for 4 weeks and without contraindication for NPWT were allowed to be included.
   Interventions NPWT was compared with standard moist wound care (SMWC) according to local standards and guidelines.
   Primary and secondary outcome measures Primary outcome was wound closure within 16 weeks. Secondary outcomes were wound-related and treatment-related adverse events (AEs), amputations, time until optimal wound bed preparation, wound size and wound tissue composition, pain and quality of life (QoL) within 16 weeks, and recurrences and wound closure within 6 months.
   Results In the ITT population, neither the wound closure rate (difference: n=4 (2.5% (95% CI-4.7% - 9.7%); p=0.53)) nor the time to wound closure (p=0.244) was significantly different between the treatment arms. 191 participants (NPWT 127; SMWC 64) had missing endpoint documentations, premature therapy ends or unauthorised treatment changes. 96 participants in the NPWT arm and 72 participants in the SMWC arm had at least one AE (p=0.007), but only 16 AEs were related to NPWT.
   Conclusions NPWT was not superior to SMWC in diabetic foot wounds in German clinical practice. Overall, wound closure rate was low. Documentation deficits and deviations from treatment guidelines negatively impacted the outcome wound closure.
C1 [Seidel, Doerthe] Univ Witten Herdecke, IFOM, Cologne, Germany.
   [Storck, Martin] Stadtisches Klinikum Karlsruhe gGmbH, Klin Gefass & Thoraxchirurg, Karlsruhe, Germany.
   [Lawall, Holger] Max Grundig Klin, Innere Med, Buhlerhohe, Germany.
   [Wozniak, Gernold] Knappschaftskrankenhaus Bottrop GmbH, Gefasschirurg Klin, Bottrop, Germany.
   [Mauckner, Peter] St Remigius Krankenhaus Opladen, Innere Med, Leverkusen, Germany.
   [Hochlenert, Dirk] Gemeinschaftspraxis Schlotmann Hochlenert Zavalet, Cologne, Germany.
   [Wetzel-Roth, Walter] Chirurg Praxis Wetzel Roth, Buchloe, Germany.
   [Sondern, Klemens] Marien Hosp Dortmund Hombruch, Klin Innere Med Diabetol, Dortmund, Germany.
   [Hahn, Matthias] Helfenstein Klin, Allgemein & Viszeralchirurg, Geisslingen, Germany.
   [Rothenaicher, Gerhard] Chirurg Praxis Rothenaicher, Munich, Germany.
   [Kroenert, Thomas] Thuringen Kliniken Georgius Agr GmbH, Klin Gefasschirurg, Saalfeld, Germany.
   [Zink, Karl] Diabet Zentrum Mergentheim, Diabet Klin, Bad Mergentheim, Germany.
   [Neugebauer, Edmund] Univ Witten Herdecke, Dept Humanmed, Witten, Germany.
   [Neugebauer, Edmund] Med Hsch Brandenburg Theodor Fontane, Neuruppin, Germany.
C3 Witten Herdecke University; Witten Herdecke University
RP Seidel, D (通讯作者)，Univ Witten Herdecke, IFOM, Cologne, Germany.
EM Doerthe.Seidel@uni-wh.de
RI /L-6893-2017
FU KCI; SN
FX Through a European tender, the study was initiated by a consortium of 19
   statutory German health insurance funds, which provided integrated care
   contracts for all study participants and for up to 7000 patients with
   acute and chronic wounds in Germany; defined basic rules for study
   design based on the requirements of the German authorities; and provided
   a critical review of the study protocol and the final report. The study
   was funded by the manufacturers KCI and S&N. Both companies provided the
   NPWT devices and associated consumable supplies in the assigned regions
   of Germany as well as all necessary support and information about the
   used material. All authors had full access to all of the data (including
   statistical reports and tables) in the study and take full
   responsibility for the accuracy of the data analysis.
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NR 33
TC 68
Z9 88
U1 4
U2 24
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 2044-6055
J9 BMJ OPEN
JI BMJ Open
PD MAR
PY 2020
VL 10
IS 3
AR e026345
DI 10.1136/bmjopen-2018-026345
PG 16
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA LG0KT
UT WOS:000527801000001
PM 32209619
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Anesäter, E
   Borgquist, O
   Torbrand, C
   Roupé, KM
   Ingemansson, R
   Lindstedt, S
   Malmsjö, M
AF Anesater, Erik
   Borgquist, Ola
   Torbrand, Christian
   Roupe, K. Markus
   Ingemansson, Richard
   Lindstedt, Sandra
   Malmsjo, Malin
TI The use of a rigid disc to protect exposed structures in wounds treated
   with negative pressure wound therapy: Effects on wound bed pressure and
   microvascular blood flow
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; POSTSTERNOTOMY MEDIASTINITIS; EXPERIENCE;
   RUPTURE
AB There are increasing reports of deaths and serious complications associated with the use of negative pressure wound therapy (NPWT). Bleeding may occur in patients when NPWT is applied to a wound with exposed blood vessels or vascular grafts, possibly due to mechanical deformation and hypoperfusion of the vessel walls. Recent evidence suggests that using a rigid barrier disc to protect underlying tissue can prevent this mechanical deformation. The aim of this study was to examine the effect of rigid discs on the tissue exposed to negative pressure with regard to tissue pressure and microvascular blood flow. Peripheral wounds were created on the backs of eight pigs. The pressure and microvascular blood flow in the wound bed were measured when NPWT was applied. The wound was filled with foam, and rigid discs of different designs were inserted between the wound bed and the foam. The discs were created with or without channels (to accommodate exposed sensitive structures such as blood vessels and nerves), perforations, or a porous dressing that covered the underside of the discs (to facilitate pressure transduction and fluid evacuation). When comparing the results for pressure transduction to the wound bed, no significant differences were found using different discs covered with dressing, whereas pressure transduction was lower with bare discs. Microvascular blood flow in the wound bed decreased by 49?+/-?7% when NPWT was applied to control wounds. The reduction in blood flow was less in the presence of a protective disc (e.g., -6?+/-?5% for a dressing-covered, perforated disc, p?=?0.006). In conclusion, NPWT causes hypoperfusion of superficial tissue in the wound bed. The insertion of a rigid barrier counteracts this effect. The placement of a rigid disc over exposed blood vessels or nerves may protect these structures from rupture and damage.
C1 [Anesater, Erik; Borgquist, Ola; Torbrand, Christian; Roupe, K. Markus; Malmsjo, Malin] Lund Univ, Dept Ophthalmol, Lund, Sweden.
   [Anesater, Erik; Borgquist, Ola; Torbrand, Christian; Roupe, K. Markus; Ingemansson, Richard; Lindstedt, Sandra; Malmsjo, Malin] Skane Univ Hosp, Lund, Sweden.
   [Borgquist, Ola] Lund Univ, Dept Anesthesiol, Lund, Sweden.
   [Torbrand, Christian] Lund Univ, Dept Urol, Lund, Sweden.
   [Ingemansson, Richard; Lindstedt, Sandra] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
C3 Lund University; Lund University; Skane University Hospital; Lund
   University; Lund University; Lund University
RP Malmsjö, M (通讯作者)，BMC A13, SE-22184 Lund, Sweden.
EM malin.malmsjo@med.lu.se
RI Torbrand, Christian/HIZ-8092-2022; Roupé, Markus/K-6502-2014; Lindstedt,
   Sandra/AEM-2892-2022; Borgquist, Ola/AAO-6451-2020
OI Torbrand, Christian/0000-0001-6442-7554; Roupé,
   Markus/0000-0001-5472-8134; Maljö, Malin/0000-0001-9849-9599;
   Ingemansson, Richard/0000-0001-7623-8953; Lindstedt,
   Sandra/0000-0003-4484-6473; 
FU Swedish Medical Research Council, Lund University Faculty of Medicine;
   Swedish Government Grant for Clinical Research, Lund University Hospital
   Research Grants; Swedish Medical Association; Royal Physiographic
   Society in Lund; Ake Wiberg Foundation; Anders Otto Sward
   Foundation/Ulrika Eklund Foundation; Magn Bergvall Foundation; Crafoord
   Foundation; Anna-Lisa and Sven-Erik Nilsson Foundation; Jeansson
   Foundation; Swedish Heart-Lung Foundation; Anna and Edvin Berger's
   Foundation; Marta Lundqvist Foundation; Lars Hierta Memorial Foundation
FX This study was supported by the Swedish Medical Research Council, Lund
   University Faculty of Medicine, the Swedish Government Grant for
   Clinical Research, Lund University Hospital Research Grants, the Swedish
   Medical Association, the Royal Physiographic Society in Lund, the Ake
   Wiberg Foundation, the Anders Otto Sward Foundation/Ulrika Eklund
   Foundation, the Magn Bergvall Foundation, the Crafoord Foundation, the
   Anna-Lisa and Sven-Erik Nilsson Foundation, the Jeansson Foundation, the
   Swedish Heart-Lung Foundation, Anna and Edvin Berger's Foundation, the
   Marta Lundqvist Foundation, and the Lars Hierta Memorial Foundation.
CR [Anonymous], PLAST RECONSTR SURG
   [Anonymous], S ADV WOUND CAR 2012
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NR 25
TC 10
Z9 12
U1 0
U2 10
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JUL-AUG
PY 2012
VL 20
IS 4
BP 611
EP 616
DI 10.1111/j.1524-475X.2012.00801.x
PG 6
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 967HA
UT WOS:000305896300019
PM 22672059
OA Bronze
DA 2026-07-24
ER

PT J
AU Lindstedt, S
   Malmsjö, M
   Hansson, J
   Hlebowicz, J
   Ingemansson, R
AF Lindstedt, Sandra
   Malmsjo, Malin
   Hansson, Johan
   Hlebowicz, Joanna
   Ingemansson, Richard
TI Pressure transduction and fluid evacuation during conventional negative
   pressure wound therapy of the open abdomen and NPWT using a protective
   disc over the intestines
SO BMC SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; ABDOMINAL COMPARTMENT SYNDROME; PACK TECHNIQUE;
   7-YEAR EXPERIENCE; TEMPORARY CLOSURE; LAPAROSTOMY; FISTULAS; SEPSIS;
   WALL
AB Background: Negative pressure wound therapy (NPWT) has gained acceptance among surgeons, for the treatment of open abdomen, since very high closure rates have been reported with this method, compared to other kinds of wound management for the open abdomen. However, the method has occasionally been associated with increased development of fistulae. We have previously shown that NPWT induces ischemia in the underlying small intestines close to the vacuum source, and that a protective disc placed between the intestines and the vacuum source prevents the induction of ischemia. In this study we compare pressure transduction and fluid evacuation of the open abdomen with conventional NPWT and NPWT with a protective disc.
   Methods: Six pigs underwent midline incision and the application of conventional NPWT and NPWT with a protective disc between the intestines and the vacuum source. The pressure transduction was measured centrally beneath the dressing, and at the anterior abdominal wall, before and after the application of topical negative pressures of -50, -70 and -120 mmHg. The drainage of fluid from the abdomen was measured, with and without the protective disc.
   Results: Abdominal drainage was significantly better (p < 0. 001) using NPWT with the protective disc at -120 mmHg (439 +/- 25 ml vs. 239 +/- 31 ml), at -70 mmHg (341 +/- 27 ml vs. 166 +/- 9 ml) and at -50 mmHg (350 +/- 50 ml vs. 151 +/- 21 ml) than with conventional NPWT. The pressure transduction was more even at all pressure levels using NPWT with the protective disc than with conventional NPWT.
   Conclusions: The drainage of the open abdomen was significantly more effective when using NWPT with the protective disc than with conventional NWPT. This is believed to be due to the more even and effective pressure transduction in the open abdomen using a protective disc in combination with NPWT.
C1 [Lindstedt, Sandra; Ingemansson, Richard] Univ Lund Hosp, Dept Cardiothorac Surg, SE-22185 Lund, Sweden.
   [Malmsjo, Malin] Univ Lund Hosp, Dept Ophthalmol, SE-22185 Lund, Sweden.
   [Hansson, Johan] Uppsala Univ, Fac Med, Inst Surg Sci, Uppsala, Sweden.
   [Hlebowicz, Joanna] Malmo Univ Hosp, Dept Med, Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital; Uppsala University; Lund University; Skane
   University Hospital
RP Lindstedt, S (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, SE-22185 Lund, Sweden.
EM sandra.lindstedt@skane.se
RI Lindstedt, Sandra/AEM-2892-2022
OI Lindstedt, Sandra/0000-0003-4484-6473; Ingemansson,
   Richard/0000-0001-7623-8953; Maljö, Malin/0000-0001-9849-9599
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NR 26
TC 15
Z9 17
U1 0
U2 4
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1471-2482
J9 BMC SURG
JI BMC Surg.
PD MAR 24
PY 2012
VL 12
AR 4
DI 10.1186/1471-2482-12-4
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 933DC
UT WOS:000303338600001
PM 22443416
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Assadian, O
   Assadian, A
   Stadler, M
   Diab-Elschahawi, M
   Kramer, A
AF Assadian, Ojan
   Assadian, Afshin
   Stadler, Maria
   Diab-Elschahawi, Magda
   Kramer, Axel
TI Bacterial growth kinetic without the influence of the immune system
   using vacuum-assisted closure dressing with and without negative
   pressure in an in vitro wound model
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Bacterial load; MRSA; Negative pressure wound therapy; Occlusive
   dressing; VAC therapy; Vacuum-assisted therapy
ID INFECTION; THERAPY
AB The physical capacity of negative pressure wound therapy (NPWT) dressing on the bacterial growth in an in vitro wound model was investigated. Standardised wounds were contaminated with a clinical Staphylococcus aureus strain and incubated at 35 degrees C for 6 hours. Four wounds were treated with continuous negative pressure (125 mmHg) and four controls without. Bacterial load per gram tissue and per gram polyurethane sponge were measured after 24, 36 and 72 hours. Without negative pressure, the initial mean S. aureus load per gram tissue was 1.42 x 10(4), with negative pressure 1.84 x 10(4), P = 0.294. After 24, 36 and 72 hours, both models yielded comparable numbers of organisms (24 hours: P = 0.081; 48 hours: P = 0.455; 72 hours: P = 0.825, respectively). Bacterial load of sponges with or without negative pressure also did not differ. Over a period of 72 hours, sponges with negative pressure yielded 1.60 x 108, those without negative pressure yielded 1.74 x 10(8) CFU/g sponge (P = 0.876). In non vital tissue without the influence of the immune system, the bacterial load did not decrease in our in vitro model using an NPWT dressing. This observation was independent of the physical effect of continuous negative pressure at 125 mmHg. The reduction in bacteria demonstrated in previous studies appears to be caused by other effects than physical suction alone. However, the results obtained are limited as non viable tissue was used and the effect of suction on dead tissue might be very different from that occurring on perfused tissue, for example, in an animal model or in patients.
C1 [Assadian, Ojan; Stadler, Maria; Diab-Elschahawi, Magda] Med Univ Vienna, Clin Inst Hyg & Med Microbiol, Div Hosp Hyg, A-1090 Vienna, Austria.
   [Assadian, Afshin] Wilhelminenspital Vienna, Dept Gen & Vasc Surg, Vienna, Austria.
   [Kramer, Axel] Ernst Moritz Arndt Univ Greifswald, Inst Hyg & Environm Med, Greifswald, Germany.
C3 Medical University of Vienna; Wilhelminenspital; Universitat Greifswald
RP Assadian, O (通讯作者)，Med Univ Vienna, Vienna Gen Hosp, Clin Inst Hyg & Med Microbiol, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
EM ojan.assadian@meduniwien.ac.at
RI ; Assadian, Ojan/H-9753-2019
OI Assadian, Ojan/0000-0003-0129-8761; Assadian, Ojan/0000-0003-0129-8761
FU Clinical Department for Hygiene and Medical Microbiology at the Medical
   University of Vienna
FX The financial support for this study was provided by the Clinical
   Department for Hygiene and Medical Microbiology at the Medical
   University of Vienna. The NPWT units and consumables used were kindly
   lent by the KCI Austria GmbH Company. The authors declare no conflict of
   interest. There has been no connection with any company or organisation,
   whose products are mentioned in this article, nor is there any link to a
   competitor for these products.
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NR 33
TC 47
Z9 56
U1 0
U2 8
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD AUG
PY 2010
VL 7
IS 4
BP 283
EP 289
DI 10.1111/j.1742-481X.2010.00686.x
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 723NS
UT WOS:000287514100008
PM 20550601
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Jiang, ZY
   Yu, XT
   Liao, XC
   Liu, MZ
   Fu, ZH
   Min, DH
   Guo, GH
AF Jiang, Zheng-Ying
   Yu, Xiao-Ting
   Liao, Xin-Cheng
   Liu, Ming-Zhuo
   Fu, Zhong-Hua
   Min, Ding-Hong
   Guo, Guang-Hua
TI Negative-pressure wound therapy in skin grafts: A systematic review and
   meta-analysis of randomized controlled trials
SO BURNS
LA English
DT Review
DE Negative-pressure therapy; Skin grafting; Systematic review;
   Meta-analysis
ID VACUUM-ASSISTED CLOSURE; INTEGRATION
AB Introduction: Although skin grafts are widely used in reconstruction of large skin defect and complex wounds, many factors lead to suboptimal graft take. Negative-pressure wound therapy (NPWT) reportedly increases the graft take rates when added to skin grafting, but a summary analysis of the data of randomized controlled trials has yet to be performed. We conducted this systematic review and meta-analysis of randomized controlled trials to compare the effectiveness and safety of NPWT and non-NPWT for patients with skin grafts.
   Methods: We searched PubMed, Embase, Cochrane Library, and CNKI for relevant trials based on predetermined eligibility criteria from database establishment to February 2020. Two reviewers screened citations and extracted data independently. The quality of the included studies was evaluated according to the Cochrane Handbook, whereas statistical heteroge-neity was assessed using chi-square tests and I2 statistics. Review Manager 5.3 was used for statistical analysis.
   Results: Ten randomized controlled trials with 488 patients who underwent NPWT or non-NPWT were included. Compared with non-NPWT, NPWT yielded an improved the percentage of graft take, a reduction in days from grafting to discharge, with lower relative risk of re-operation, and no increased relative risk of adverse event. Further, the subgroup analysis showed an improved the percentage of graft take in negative pressure of 80 mmHg, and no improved the percentage of graft take in negative pressure of 125 mmHg.
   Conclusion: NPWT is more effective than non-NPWT for the integration of skin grafts, and the negative pressure of 80 mmHg can be recommended. Data on adverse events and negative pressure are, however, limited. A better understanding of complications after NPWT and the ideal negative pressure for the integration of skin grafts is imperative.
   (c) 2021 Elsevier Ltd and ISBI. All rights reserved.
C1 [Jiang, Zheng-Ying; Yu, Xiao-Ting; Liao, Xin-Cheng; Liu, Ming-Zhuo; Fu, Zhong-Hua; Min, Ding-Hong; Guo, Guang-Hua] Nanchang Univ, Dept Burn, Affiliated Hosp 1, 17 Yong Wai St, Nanchang 330006, Jiangxi, Peoples R China.
C3 Nanchang University
RP Guo, GH (通讯作者)，Nanchang Univ, Dept Burn, Affiliated Hosp 1, 17 Yong Wai St, Nanchang 330006, Jiangxi, Peoples R China.
EM guoghtg@sina.com
FU National Natural Science Foundation of China [81960352, 81760342];
   Special Fund for Innovation of Postgraduates in Jiangxi Province, China
   [YC2020B039]; Key Program of Jiangxi Provincial Natural Science
   Foundation, China [20171ACB20031]
FX This work was supported by the National Natural Science Foundation of
   China (81760342) , the National Natural Science Foundation of China
   (81960352) , the Special Fund for Innovation of Postgraduates in Jiangxi
   Province, China (YC2020B039) , and the Key Program of Jiangxi Provincial
   Natural Science Foundation, China (20171ACB20031) .
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NR 29
TC 29
Z9 36
U1 1
U2 4
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0305-4179
EI 1879-1409
J9 BURNS
JI Burns
PD JUN
PY 2021
VL 47
IS 4
BP 747
EP 755
DI 10.1016/j.burns.2021.02.012
EA JUN 2021
PG 9
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA SS0QY
UT WOS:000661448400003
PM 33814213
DA 2026-07-24
ER

PT J
AU Cagney, D
   Simmons, L
   O'Leary, DP
   Corrigan, M
   Kelly, L
   O'Sullivan, MJ
   Liew, A
   Redmond, HP
AF Cagney, David
   Simmons, Lydia
   O'Leary, Donal Peter
   Corrigan, Mark
   Kelly, Louise
   O'Sullivan, M. J.
   Liew, Aaron
   Redmond, Henry Paul
TI The Efficacy of Prophylactic Negative Pressure Wound Therapy for Closed
   Incisions in Breast Surgery: A Systematic Review and Meta-Analysis
SO WORLD JOURNAL OF SURGERY
LA English
DT Article; Proceedings Paper
CT International Surgical Congress of the
   Association-of-Surgeons-of-Great-Britain-and-Ireland (ASGBI)
CY MAY 07-09, 2019
CL Telford, ENGLAND
SP Assoc Surg Great Britain & Ireland
ID SURGICAL SITE INFECTION; VACUUM-ASSISTED CLOSURE; COST-EFFECTIVENESS
   ANALYSIS; CARE-ASSOCIATED INFECTIONS; FINANCIAL IMPACT; MANAGEMENT;
   MASTECTOMY; PREVENTION; STANDARD; DELAY
AB Background Negative pressure wound therapy (NPWT) is a promising advance in the management of closed surgical incisions. NPWT application induces several effects locally within the wound including reduced lateral tension and improving lymphatic drainage. As a result, NPWT may improve wound healing and reduce surgical site complications. We aim to evaluate the efficacy of prophylactic application of NPWT in preventing surgical site complications for closed incisions in breast surgery. Methods This systematic review was reported according to PRISMA guidelines. The protocol was published in PROSPERO (CRD42018114625). Medline, Embase, CINAHL and Cochrane Library databases were searched for studies which compare the efficacy of NPWT versus non-NPWT dressings for closed incisions in breast surgery. Specific outcomes of interest were total wound complications, surgical site infection (SSI), seroma, haematoma, wound dehiscence and necrosis. Results Seven studies (1500 breast incisions in 904 patients) met the inclusion criteria. NPWT was associated with a significantly lower rate of total wound complications [odds ratio (OR) 0.36; 95% CI 0.19-069; P = 0.002], SSI (OR 0.45; 95% CI 0.24-0.86; P = 0.015), seroma (OR 0.28; 95% CI 0.13-0.59; P = 0.001), wound dehiscence (OR 0.49; 95% CI 0.32-0.72; P < 0.001) and wound necrosis (OR 0.38; 95% CI 0.19-0.78; P = 0.008). There was no significant difference in haematoma rate (OR 0.8; 95% CI 0.19-3.2; P = 0.75). Statistically significant heterogeneity existed for total wound complications, but no other outcomes. Conclusion Compared with conventional non-NPWT dressings, prophylactic application of NPWT is associated with significantly fewer surgical site complications including SSI, seroma, wound dehiscence and wound necrosis for closed breast incisions.
C1 [Cagney, David; Simmons, Lydia; O'Leary, Donal Peter; Corrigan, Mark; Kelly, Louise; O'Sullivan, M. J.; Redmond, Henry Paul] Cork Univ Hosp, Dept Surg, Cork, Ireland.
   [Liew, Aaron] Natl Univ Ireland, Galway, Ireland.
   [Liew, Aaron] Portiuncula Univ Hosp, Galway, Ireland.
   [Corrigan, Mark; Kelly, Louise; O'Sullivan, M. J.] Cork Univ Hosp, Breast Canc Res Ctr, Cork, Ireland.
C3 University College Cork; Ollscoil na Gaillimhe-University of Galway;
   University College Cork
RP Cagney, D (通讯作者)，Cork Univ Hosp, Dept Surg, Cork, Ireland.
EM cagney.davej@gmail.com
OI Corrigan, Mark/0000-0002-9615-6450; Cagney, David/0000-0001-5505-3175
CR [Anonymous], 2016, Global Guidelines for the Prevention of Surgical Site Infection
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NR 43
TC 51
Z9 55
U1 1
U2 5
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD MAY
PY 2020
VL 44
IS 5
BP 1526
EP 1537
DI 10.1007/s00268-019-05335-x
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA KY8OY
UT WOS:000522837000024
PM 31900568
DA 2026-07-24
ER

PT J
AU Vas, P
   Rayman, G
   Dhatariya, K
   Driver, V
   Hartemann, A
   Londahl, M
   Piaggesi, A
   Apelqvist, J
   Attinger, C
   Game, F
AF Vas, Prashanth
   Rayman, Gerry
   Dhatariya, Ketan
   Driver, Vickie
   Hartemann, Agnes
   Londahl, Magnus
   Piaggesi, Alberto
   Apelqvist, Jan
   Attinger, Chris
   Game, Fran
TI Effectiveness of interventions to enhance healing of chronic foot ulcers
   in diabetes: a systematic review
SO DIABETES-METABOLISM RESEARCH AND REVIEWS
LA English
DT Review
DE debridement; diabetic foot; dressing; foot ulcer; guidelines; hyperbaric
   oxygen; negative pressure wound therapy; placental-derived products;
   topical oxygen; wound healing
ID HYPERBARIC-OXYGEN THERAPY; PRESSURE WOUND THERAPY; COLONY-STIMULATING
   FACTOR; VACUUM-ASSISTED CLOSURE; RANDOMIZED CONTROLLED-TRIAL; CONTROLLED
   CLINICAL-TRIAL; EPIDERMAL-GROWTH-FACTOR; CRITICAL LIMB ISCHEMIA;
   INTERMITTENT PNEUMATIC COMPRESSION; AMNIOTIC MEMBRANE ALLOGRAFT
AB The management of diabetic foot ulcers (DFU) remains a challenge, and there is continuing uncertainty concerning optimal approaches to wound healing. The International Working Group of the Diabetic Foot (IWGDF) working group on wound healing has previously published systematic reviews of the evidence in 2008, 2012 and 2016 to inform protocols for routine care and to highlight areas which should be considered for further study. The working group has now updated this review by considering papers on the interventions to improve the healing of DFU's published between June 2014 and August 2018. Methodological quality of selected studies was independently assessed by a minimum of two reviewers using the recently published 21-point questionnaire as recommended by IWGDF/European Wound Management Association, as well as the previously incorporated Scottish Intercollegiate Guidelines Network criteria. Of the 2275 papers identified, 97 were finally selected for grading following full text review. Overall, there has been an improvement in study design and a significant rise in the number of published studies. While previous systematic reviews did not find any evidence to justify the use of newer therapies, except for negative pressure wound therapy in post-surgical wounds, in this review we found additional evidence to support some interventions including a sucrose-octasulfate dressing, the combined leucocyte, fibrin and platelet patch as well as topical application of some placental membrane products, all when used in addition to usual best care. Nonetheless, the assessment and comparison of published trials remains difficult with marked clinical heterogeneity between studies: in patient selection, study duration, standard of usual care provision and the timing and description of the clinical endpoints.
C1 [Vas, Prashanth] Kings Coll Hosp London, Diabet Foot Clin, London, England.
   [Rayman, Gerry] East Suffolk & North East Essex Fdn Trust, Diabet Ctr, Colchester, Essex, England.
   [Rayman, Gerry] East Suffolk & North East Essex Fdn Trust, Res Unit, Colchester, Essex, England.
   [Dhatariya, Ketan] Univ East Anglia, Norfolk & Norwich Univ Hosp NHS Fdn Trust, Dept Diabet, Norwich, Norfolk, England.
   [Driver, Vickie] Brown Univ, Sch Med, Providence, RI 02912 USA.
   [Hartemann, Agnes] Hop La Pitie Salpetriere, APHP, Paris, France.
   [Londahl, Magnus] ICAN, Lyon, France.
   [Londahl, Magnus] Lund Univ, Dept Endocrinol, Skane Univ Hosp, Lund, Sweden.
   [Londahl, Magnus] Lund Univ, Dept Clin Sci, Lund, Sweden.
   [Piaggesi, Alberto] Univ Pisa, Diabet Foot Sect, Dept Med, Pisa, Italy.
   [Apelqvist, Jan] Univ Hosp Malmo, Dept Endocrinol, Malmo, Sweden.
   [Attinger, Chris] Medstar Georgetown Univ Hosp, Dept Plast Surg, Washington, DC USA.
   [Game, Fran] Univ Hosp Derby & Burton NHS Fdn Trust, Dept Diabet & Endocrinol, Derby, England.
C3 King's College Hospital NHS Foundation Trust; King's College Hospital;
   University of East Anglia; Norfolk & Norwich University Hospitals NHS
   Foundation Trust; Brown University; Sorbonne Universite; Assistance
   Publique Hopitaux Paris (APHP); Hopital Universitaire Ambroise-Pare -
   APHP; Hopital Universitaire Pitie-Salpetriere - APHP; Universite Paris
   Cite; Hopital Universitaire Hotel-Dieu - APHP; Institut National de la
   Sante et de la Recherche Medicale (Inserm); Lund University; Skane
   University Hospital; Lund University; University of Pisa; Lund
   University; Skane University Hospital; Georgetown University
RP Vas, P (通讯作者)，Kings Coll Hosp London, Diabet Foot Clin, London, England.
EM prashanth.vas@nhs.net
RI ; Rayman, Gerry/KLZ-2200-2024
OI Löndahl, Magnus/0000-0003-1522-3920; Vas, Prashanth/0000-0001-7448-2995;
   Game, Frances/0000-0002-5294-4789
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   Xu JS, 2018, EXP THER MED, V15, P5365, DOI 10.3892/etm.2018.6131
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   You HJ, 2014, J WOUND CARE, V23, P521, DOI 10.12968/jowc.2014.23.11.521
   You HJ, 2012, WOUND REPAIR REGEN, V20, P491, DOI 10.1111/j.1524-475X.2012.00809.x
   Yu J, 2016, WOUND REPAIR REGEN, V24, P1066, DOI 10.1111/wrr.12490
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NR 235
TC 63
Z9 78
U1 2
U2 36
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1520-7552
EI 1520-7560
J9 DIABETES-METAB RES
JI Diabetes-Metab. Res. Rev.
PD MAR
PY 2020
VL 36
SU 1
DI 10.1002/dmrr.3284
PG 23
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA MZ6RW
UT WOS:000559257300036
PM 32176446
OA Bronze
DA 2026-07-24
ER

PT J
AU Naylor, RM
   Gilder, HE
   Gupta, N
   Hydrick, TC
   Labott, JR
   Mauler, DJ
   Trentadue, TP
   Ghislain, B
   Elder, BD
   Fogelson, JL
AF Naylor, Ryan M.
   Gilder, Hannah E.
   Gupta, Nikita
   Hydrick, Thomas C.
   Labott, Joshua R.
   Mauler, David J.
   Trentadue, Taylor P.
   Ghislain, Brandon
   Elder, Benjamin D.
   Fogelson, Jeremy L.
TI Effects of Negative Pressure Wound Therapy on Wound Dehiscence and
   Surgical Site Infection Following Instrumented Spinal Fusion Surgery-A
   Single Surgeon's Experience
SO WORLD NEUROSURGERY
LA English
DT Article
DE NPWT; Prevention; Spine fusion; Surgical wound complications
ID VACUUM ASSISTED CLOSURE; LUMBAR FUSION; MANAGEMENT; COMPLICATIONS;
   MECHANISMS; INCISION; RISK
AB BACKGROUND: Incisional negative pressure wound therapy (NPWT) is used in many surgical specialties to prevent postoperative dehiscence and surgical site infections (SSIs). However, little is known about the role of incisional NPWT in spine fusion surgery. Therefore, we sought to report a single surgeon's experience using incisional NPWT and describe its effects on dehiscence and SSIs after instrumented spine surgery.
   METHODS: We compared rates of hospital readmission and return to the operating room for dehiscence and SSIs in a consecutive series of patients who underwent spinal fusion surgery with or without NPWT from 2015 to 2018.
   RESULTS: A total of 393 patients without and 76 patients with NPWTwere included for analysis. Half way through the data collection period, all patients who underwent anterior lumbar fusion received NPWT. Three of 15 (20.0%) of nonNPWT patients who underwent anterior lumbar fusion had dehiscence or SSI compared with zero of 23 (0.0%) of NPWT patients (P = 0.01). NPWT for posterior surgeries was used on a case-by-case basis using risk factors that contribute to SSIs and dehiscence. NPWT patients had higher rates of spinal neoplasia (0.5% vs. 11.3%, P < 0.0001), osteomyelitis/diskitis (1.3% vs. 7.5%, P = 0.02), durotomy (14.9% vs. 28.6%, P = 0.007), revision surgery (32.2% vs. 59.6%, P = 0.0001), and longer fusion constructs (7 vs. 11 levels, P < 0.0001) but had similar rates of dehiscence and SSIs as non-NPWT patients (5.6% vs. 5.7%, P = 0.98).
   CONCLUSIONS: NPWT decreases dehiscence and SSIs in patients undergoing lumbar fusion through an anterior approach. When preferentially used in patients at high risk for postoperative wound complications, NPWT prevents increased rates of dehiscence and SSI.
C1 [Naylor, Ryan M.; Gilder, Hannah E.; Elder, Benjamin D.; Fogelson, Jeremy L.] Mayo Clin, Dept Neurol Surg, Rochester, MN 55905 USA.
   [Labott, Joshua R.; Trentadue, Taylor P.; Ghislain, Brandon] Mayo Clin, Alix Sch Med, Rochester, MN USA.
   [Trentadue, Taylor P.] Mayo Clin, Med Scientist Training Program, Rochester, MN USA.
   [Elder, Benjamin D.; Fogelson, Jeremy L.] Mayo Clin, Dept Orthoped Surg, Rochester, MN 55905 USA.
   [Elder, Benjamin D.] Mayo Clin, Dept Biomed Engn, Rochester, MN USA.
   [Gupta, Nikita; Hydrick, Thomas C.; Mauler, David J.] Mayo Clin, Alix Sch Med, Scottsdale, AZ USA.
C3 Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo
   Clinic; Mayo Clinic Phoenix
RP Fogelson, JL (通讯作者)，Mayo Clin, Dept Neurol Surg, Rochester, MN 55905 USA.; Fogelson, JL (通讯作者)，Mayo Clin, Dept Orthoped Surg, Rochester, MN 55905 USA.
EM fogelson.jeremy@mayo.edu
RI Naylor, Ryan/AFP-1072-2022
OI GUPTA, NIKITA/0000-0003-3098-6598; Mauler, David/0000-0003-0247-5854;
   Trentadue, Taylor/0000-0002-0390-3243
FU National Institute of General Medical Sciences [T32GM065841] Funding
   Source: NIH RePORTER; NIGMS NIH HHS [T32 GM065841] Funding Source:
   Medline
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
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NR 28
TC 22
Z9 25
U1 0
U2 5
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1878-8750
EI 1878-8769
J9 WORLD NEUROSURG
JI World Neurosurg.
PD MAY
PY 2020
VL 137
BP E257
EP E262
DI 10.1016/j.wneu.2020.01.152
PG 6
WC Clinical Neurology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA LN1TU
UT WOS:000532728700012
PM 32004742
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Bakaeen, FG
   Haddad, O
   Ibrahim, M
   Pasadyn, SR
   Germano, E
   Mok, S
   Halbreiner, MS
   McCurry, KR
   Johnston, DR
   Mick, SL
   Navia, JL
   Roselli, EE
   Smedira, NG
   Soltesz, EG
   Tong, MZ
   Wierup, P
   Gillinov, AM
   Svensson, LG
   Houghtaling, PL
   Blackstone, EH
   Pettersson, GB
AF Bakaeen, Faisal G.
   Haddad, Osama
   Ibrahim, Mudathir
   Pasadyn, Selena R.
   Germano, Emidio
   Mok, Salvior
   Halbreiner, M. Scott
   McCurry, Kenneth R.
   Johnston, Douglas R.
   Mick, Stephanie L.
   Navia, Jose L.
   Roselli, Eric E.
   Smedira, Nicholas G.
   Soltesz, Edward G.
   Tong, Michael Z.
   Wierup, Per
   Gillinov, A. Marc
   Svensson, Lars G.
   Houghtaling, Penny L.
   Blackstone, Eugene H.
   Pettersson, Gosta B.
TI Advances in managing the noninfected open chest after cardiac surgery:
   Negative-pressure wound therapy
SO JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article; Proceedings Paper
CT 98th Annual Meeting of the American-Association-for-Thoracic-Surgery
   (AATS)
CY APR 28-MAY 18, 2018
CL San Diego, CA
SP Amer Assoc Thorac Surg
DE hemodynamics; coagulopathy; survival; propensity score
ID DELAYED STERNAL CLOSURE; VACUUM-ASSISTED CLOSURE; STERNOTOMY; INFECTION;
   TRANSFUSION; COMPRESSION; HEMORRHAGE; TAMPONADE; RISK
AB Objective: The objective of this study was to compare safety and clinical effectiveness of negative-pressure wound therapy (NPWT) with traditional wound therapy for managing noninfected open chests with delayed sternal closure after cardiac surgery.
   Methods: From January 2000 to July 2015, 452 of 47,325 patients who underwent full sternotomy left the operating room with a noninfected open chest (0.96%), managed using NPWT in 214-with frequency of use rapidly increasing to near 100%-and traditionally in 238. Predominant indications for open-chest management were uncontrolled coagulopathy or hemodynamic compromise on attempted chest closure. Weighted propensity-score matching was used to assess in-hospital complications and time-related survival.
   Results: NPWT and traditionally managed patients had similar high-risk preoperative profiles. Most underwent reoperations (63% of the NPWT group and 57% of the traditional group), and 21% versus 25% were emergency procedures. Reexplorations for bleeding were less common with NPWT versus traditional wound therapy (n = 63 [29%] vs 104 [44%], P =.002). Median duration of open-chest to definitive sternal closure was 3.5 days for NPWT versus 3.1 for traditionally managed patients (P[log rank] =.07). Seven patients (3.3%) were converted from NPWT to traditional therapy because of hemodynamic intolerance and 6 (2.5%) from traditional to NPWT. No NPWT-related cardiovascular injuries occurred. Among matched patients, NPWT was associated with better early survival (61% vs 44% at 6 months; P =.02).
   Conclusions: NPWT is safe and effective for managing noninfected open chests after cardiac surgery. By facilitating open-chest management and potentially improving outcomes, it has become our therapy of choice and perhaps has lowered our threshold for leaving the chest open after cardiac surgery.
C1 [Bakaeen, Faisal G.; Haddad, Osama; Ibrahim, Mudathir; Pasadyn, Selena R.; Germano, Emidio; Mok, Salvior; Halbreiner, M. Scott; McCurry, Kenneth R.; Johnston, Douglas R.; Mick, Stephanie L.; Navia, Jose L.; Roselli, Eric E.; Smedira, Nicholas G.; Soltesz, Edward G.; Tong, Michael Z.; Wierup, Per; Gillinov, A. Marc; Svensson, Lars G.; Blackstone, Eugene H.; Pettersson, Gosta B.] Cleveland Clin, Dept Thorac & Cardiovasc Surg, Inst Heart & Vasc, Cleveland, OH 44106 USA.
   [Houghtaling, Penny L.; Blackstone, Eugene H.] Cleveland Clin, Dept Quantitat Hlth Sci, Res Inst, Cleveland, OH 44106 USA.
C3 Cleveland Clinic Foundation; Cleveland Clinic Foundation
RP Pettersson, GB (通讯作者)，Cleveland Clin, Dept Thorac & Cardiovasc Surg, 9500 Euclid Ave Desk J4-1, Cleveland, OH 44915 USA.
EM petterg@ccf.org
RI ; IBRAHIM, MUDATHIR/AAZ-1557-2020; Haddad, Osama/AAY-3238-2021; mok,
   salvior/NBY-2568-2025; Svensson, Lars/ABY-1869-2022
OI Blackstone, Eugene/0000-0001-9839-3567; IBRAHIM,
   MUDATHIR/0000-0002-6345-1533; , Sal/0009-0009-0183-2048; Haddad,
   Osama/0000-0001-6308-6372; 
FU Gus P. Karos Registry Fund; David Whitmire Hearst, Jr. Foundation; Marty
   and Michelle Weinberg and Family Fund; Sheikh Hamdan bin Rashid Al
   Maktoum Distinguished Chair in Thoracic and Cardiovascular Surgery;
   Stephens Family Endowed Chair in Cardiothoracic Surgery; Delos M.
   Cosgrove, MD, Chair for Heart Disease Research; Drs Sidney and Becca
   Fleischer Heart and Vascular Education Chair; Peter and Elizabeth C.
   Tower and Family Endowed Chair in Cardiothoracic Research; Slosburg
   Family Charitable Trust
FX This study was funded in part by the Gus P. Karos Registry Fund, the
   David Whitmire Hearst, Jr. Foundation, the Marty and Michelle Weinberg
   and Family Fund, the Sheikh Hamdan bin Rashid Al Maktoum Distinguished
   Chair in Thoracic and Cardiovascular Surgery, the Stephens Family
   Endowed Chair in Cardiothoracic Surgery, the Delos M. Cosgrove, MD,
   Chair for Heart Disease Research, the Drs Sidney and Becca Fleischer
   Heart and Vascular Education Chair, the Peter and Elizabeth C. Tower and
   Family Endowed Chair in Cardiothoracic Research, James and Sharon
   Kennedy, the Slosburg Family Charitable Trust, Stephen and Saundra
   Spencer, and Martin Nielsen.
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NR 35
TC 19
Z9 22
U1 0
U2 5
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0022-5223
EI 1097-685X
J9 J THORAC CARDIOV SUR
JI J. Thorac. Cardiovasc. Surg.
PD MAY
PY 2019
VL 157
IS 5
BP 1891
EP +
DI 10.1016/j.jtcvs.2018.10.152
PG 21
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA HT3AY
UT WOS:000464437100077
PM 30709676
OA Bronze
DA 2026-07-24
ER

PT J
AU Anagnostakos, K
   Mosser, P
AF Anagnostakos, K.
   Mosser, P.
TI Bacteria identification on NPWT foams: clinical relevance or
   contamination?
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE negative pressure wound therapy; bacteria growth; microbiological
   findings; bone infection
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; NEGATIVE-PRESSURE;
   BIOFILM FORMATION; STAPHYLOCOCCUS-AUREUS; GROWING BACTERIA; FOUNDATION;
   CANDIDA; STATE; MODEL
AB Objective: To compare and interpret the microbiological findings of tissue samples prior to and during negative pressure wound therapy (NPWT), as well as those of NPWT foams.
   Method: A retrospective evaluation of 101 NPWT dressings (29 polyurethane, 72 polyvinylalcohol; 43 deeply inserted, 56 superficially, two combined deeply and superficially; 67 hardware present and 34 no hardware present) in 64 patients was conducted. All foam and tissue samples were cultured over a period of 7 days. Tissue and foam samples were incubated on blood agar plates and in tryptic soya broth. Positive results indicated a microbial growth with > 10(5) colony forming units (CFU)/ml.
   Results: Total mean implantation period was 6 +/- 2 days (2-14 days). On 39 foams (39%), at least one organism could be identified. While S. aureus and S. epidermidis were the most common organisms prior to NPWT, during therapy S. epidermidis and S. aureus were most frequently identified in the tissue samples, with E. faecalis and S. epidermidis on the foams. In 12 cases (31%), the organisms in the tissue samples during NPWT and on the foams were identical, whereas in two cases a different organism was evident on the foam. In 6 cases (15%) the microbiological examination of the tissue samples was negative while positive on the foam. In the remaining 19 cases (54%), an organism could be identified on the foams while no tissue samples were microbiologically examined.
   Conclusion:This study shows that, in at least 20% of the cases, a bacterium might be solely identified on the NPWT foam or differ to those isolated in the tissue; whether this is a contamination, bacterial switch or the results of insufficient microbiological diagnostics prior to NPWT cannot be surely stated.
C1 [Anagnostakos, K.; Mosser, P.] Univ Hosp Saarland, Dept Orthopaed Surg, Saarland, Germany.
C3 Universitatsklinikum des Saarlandes
RP Anagnostakos, K (通讯作者)，Univ Hosp Saarland, Dept Orthopaed Surg, Saarland, Germany.
EM k.anagnostakos@web.de
RI Anagnostakos, Konstantinos/MGC-8753-2025
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NR 21
TC 14
Z9 16
U1 0
U2 8
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
J9 J WOUND CARE
JI J. Wound Care
PD JUL
PY 2012
VL 21
IS 7
BP 333
EP +
DI 10.12968/jowc.2012.21.7.333
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 973VJ
UT WOS:000306387600006
PM 22886333
DA 2026-07-24
ER

PT J
AU Hall, C
   Regner, J
   Abernathy, S
   Isbell, C
   Isbell, T
   Kurek, S
   Smith, R
   Frazee, R
AF Hall, Chad
   Regner, Justin
   Abernathy, Stephen
   Isbell, Claire
   Isbell, Travis
   Kurek, Stan
   Smith, Randall
   Frazee, Richard
TI Surgical Site Infection after Primary Closure of High-Risk Surgical
   Wounds in Emergency General Surgery Laparotomy and Closed
   Negative-Pressure Wound Therapy
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Article; Proceedings Paper
CT 130th Annual Meeting of the Southern-Surgical-Association
CY DEC, 2018
CL Palm Beach, FL
SP So Surg Assoc
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED-TRIAL; MANAGEMENT; METAANALYSIS;
   SYSTEM
AB BACKGROUND: We hypothesized that the universal adoption of closed wounds with negative pressure wound therapy (NPWT) in emergency general surgery patients would result in low superficial surgical infection (SSI) rates.
   STUDY DESIGN: We performed a retrospective observational study using primary wound closure with external NPWT, from May 2017 to May 2018. Patients with active soft tissue infection of the abdominal wall were excluded. Data were analyzed by Fisher's exact tests and Wilcoxon-Mann-Whitney tests, with significance is set at a value of p < 0.05.
   RESULTS: Eighty-five patients (53% female) with a median age of 65 years (range 19 to 98 years) underwent laparotomies. Four patients were excluded for active soft tissue infection. Wounds were classified as dirty (n = 18), contaminated (n = 52), and clean contaminated (n = 11). Median BMI was 27 kg/m(2) (interquartile range [IQR] 23.4 to 33.0 kg/m(2)). Median antibiotic therapy was 4 days (IQR 1 to 7 days). Twenty-six patients had open abdomen management. Patient follow-up was a median of 20 days (range 14 to 120 days). Six patients (7%) developed superficial SSI requiring conversion to open wound management. No patients developed fascial dehiscence. There were no statistically significant associations between SSI and wound class (p = 0.072), antibiotic duration (p = 0.702), open abdomen management, or preoperative risk factors (p < 0.1). Overall morbidity was 38% and mortality was 6%.
   CONCLUSIONS: Primary closure of high risk incisions combined with NPWT is associated with acceptably low SSI rates. Due to the low morbidity and decreased cost associated with this technique, primary closure with NPWT should replace open wound management in the emergency general surgery population. (C) 2018 by the American College of Surgeons. Published by Elsevier Inc. All rights reserved.
C1 [Hall, Chad; Regner, Justin; Abernathy, Stephen; Isbell, Claire; Isbell, Travis; Kurek, Stan; Smith, Randall; Frazee, Richard] Baylor Scott & White Mem Hosp, Dept Trauma & Acute Care Surg, Temple, TX USA.
C3 Baylor Scott & White Health
RP Frazee, R (通讯作者)，2401 S 31st St, Temple, TX 76508 USA.
EM Richard.frazee@bswhealth.org
OI Kurek, Stanley/0000-0001-6608-5404
CR Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
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NR 17
TC 28
Z9 39
U1 0
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD APR
PY 2019
VL 228
IS 4
BP 393
EP 397
DI 10.1016/j.jamcollsurg.2018.12.006
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA HP0LI
UT WOS:000461357100012
PM 30586643
DA 2026-07-24
ER

PT J
AU Wilkin, G
   Khogali, S
   Garbedian, S
   Slagel, B
   Blais, S
   Gofton, W
   Liew, A
   Renaud, JM
   Papp, S
AF Wilkin, Geoffrey
   Khogali, Shiemaa
   Garbedian, Shawn
   Slagel, Bradley
   Blais, Simon
   Gofton, Wade
   Liew, Allan
   Renaud, Jean-Marc
   Papp, Steven
TI Negative-Pressure Wound Therapy After Fasciotomy Reduces Muscle-Fiber
   Regeneration in a Pig Model
SO JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MICROVASCULAR BLOOD-FLOW; RANDOMIZED
   CONTROLLED-TRIAL; SOFT-TISSUE INJURIES; SKELETAL-MUSCLE; COMPARTMENT
   SYNDROME; ISCHEMIA; EXPERIENCE; MANAGEMENT; DEVICE
AB Background: Negative-pressure wound therapy (NPWT) can improve fasciotomy wound closure, but its effects on skeletal muscle are largely unknown. The purpose of this study was to evaluate NPWT effects on skeletal muscle after fasciotomy for compartment syndrome in an animal model and to assess regional variability in muscle fiber regeneration.
   Methods: Compartment syndrome was induced in the hindlimb of twenty-two adult female pigs with use of a continuous intracompartmental serum-infusion model. Fasciotomy was performed after six hours, and animals were randomized to receive either wet-to-dry gauze dressings (control group) or NPWT dressings (2125 mm Hg, continuous suction) for seven days. Delayed primary wound closure was attempted at seven days, and the peroneus tertius was harvested for analysis seven days or twenty-one days after fasciotomy. Muscles were weighed, and hematoxylin and eosin-stained samples from four regions of the muscle (superficial central, deep central, lateral, and proximal) were mapped for different cellular morphologies.
   Results: Muscle weight was greater in the affected limb at all time points with no difference between treatment groups. At seven days, only the deep central samples in the NPWT group had a significantly greater cross-sectional area containing normal fibers as compared with that found in the controls. By twenty-one days, the deep central, lateral, and proximal regions of the NPWT-treated muscles had a smaller cross-sectional area containing normal fiber morphology and a greater cross-sectional area containing only mononucleated cells as compared with the controls.
   Conclusions: NPWT did not decrease muscle weight. At twenty-one days, the extent of muscle fiber regeneration after fasciotomy for compartment syndrome was reduced in muscles treated with NPWT for seven days compared with the values in the control group treated with wet-to-dry gauze dressings.
C1 [Wilkin, Geoffrey; Gofton, Wade; Liew, Allan; Papp, Steven] Univ Ottawa, Div Orthopaed Surg, Ottawa Hosp, Ottawa, ON K1Y 4E9, Canada.
   [Khogali, Shiemaa; Blais, Simon; Renaud, Jean-Marc] Univ Ottawa, Dept Cellular & Mol Med, Ottawa, ON K1H 8M5, Canada.
C3 University of Ottawa; Ottawa Hospital Research Institute; University of
   Ottawa
RP Wilkin, G (通讯作者)，Univ Ottawa, Div Orthopaed Surg, Ottawa Hosp, Civ Campus,1053 Carling Ave, Ottawa, ON K1Y 4E9, Canada.
EM geoff.wilkin@gmail.com
RI Wilkin, Geoffrey/KHU-8540-2024
OI Wilkin, Geoffrey/0000-0002-9807-7916
FU KCI Ltd (San Antonio, Texas); Canadian Institutes of Health Research
   (CIHR); Department of Surgery
FX Funding for study materials was provided by grants from KCI Ltd (San
   Antonio, Texas), the Canadian Institutes of Health Research (CIHR), and
   the institution's Department of Surgery. Funding sources had no role in
   designing or conducting the experimental procedures, in drafting the
   manuscript, or in the decision to publish the findings.
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NR 32
TC 14
Z9 19
U1 0
U2 7
PU JOURNAL BONE JOINT SURGERY
PI NEEDHAM
PA 20 PICKERING ST, NEEDHAM, MA 02492 USA
SN 0021-9355
EI 1535-1386
J9 J BONE JOINT SURG AM
JI J. Bone Joint Surg.-Am. Vol.
PD AUG 20
PY 2014
VL 96A
IS 16
BP 1378
EP 1385
DI 10.2106/JBJS.M.01010
PG 8
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA AR8BB
UT WOS:000343799400017
PM 25143498
DA 2026-07-24
ER

PT J
AU Vincent, CN
   Venkatesan, AS
   Rai, D
   Muthuswamy, AKS
AF Vincent, Chandan Noel
   Venkatesan, Aakash Sethuraman
   Rai, Dinakar
   Muthuswamy, Arvind Kumar Salem
TI The Use of Custom-Made Negative Pressure Wound Therapy to Manage Acute
   Wound Infections: A Retrospective Outcomes Study
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE infected wound; lower limb; negative pressure wound therapy; secondary
   suture; split-thickness skin graft
ID VACUUM-ASSISTED CLOSURE; STERNAL OSTEOMYELITIS; DEVICE
AB Background. NPWT has been used to treat various wounds. Scant evidence exists on the use of custom-made NPWT for infected wounds. NPWT dressings promote wound healing by increasing local blood flow and antibiotic concentration, and by removing exudates from the wound. Objective. To report the use of custom-made NPWT dressings to manage complex infected wounds of the lower limb. Materials and Methods. The authors retrospectively reviewed the records of 43 patients with complex infected wounds of the lower limb treated with debridement and low-cost, custom-made NPWT dressing connected to wall suction from January 1, 2018 to December 31, 2020, at PSG Medical College Hospital, Coimbatore, India. Results. A total of 43 patients with infected wounds of the lower limb were treated with the custom-made NPWT dressings. Second -look debridement was required in 5 patients. An average of 5 dressing changes were required for optimal wound granulation, with 23% of patients (n = 10) requiring secondary suturing and 62% (n = 27) requiring STSG for definitive coverage of the wound. Healing by secondary intention was achieved in 6 patients. The average duration from the start of therapy until the wound was ready for coverage (STSG or secondary suturing) was 2.5 weeks (range, 1-5 weeks), with an average time to complete wound healing of 5 weeks (range, 3-7 weeks). The most common wound isolate was Staphylococcus aureus (60%). No complications occurred. Conclusions. Custom-made NPWT dressings are safe to use in complex infected lower limb wounds. These dressings keep the wound dry and promote healing. Wound debridement followed by NPWT combined with antibiotic therapy can act synergistically to promote wound healing and control infection.
C1 [Vincent, Chandan Noel] Manchester Royal Infirm Hosp, Orthopaed, Manchester, England.
   [Venkatesan, Aakash Sethuraman] NHS Wales Aneurin Bevan Univ Hlth Board, Newport, Wales.
   [Rai, Dinakar; Muthuswamy, Arvind Kumar Salem] PSG Inst Med Sci & Res, Coimbatore, India.
   [Vincent, Chandan Noel] Manchester Royal Infirm, Orthopaed, Oxford Rd, Manchester M13 9WL, England.
C3 University of Manchester
RP Vincent, CN (通讯作者)，Manchester Royal Infirm, Orthopaed, Oxford Rd, Manchester M13 9WL, England.
EM chandannoel@gmail.com
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NR 27
TC 0
Z9 0
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD MAR
PY 2024
VL 36
IS 3
BP 90
EP 94
DI 10.25270/wnds/23102
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA QM3U1
UT WOS:001221259200004
PM 38684124
DA 2026-07-24
ER

PT J
AU Gruener, JS
   Horch, RE
   Geierlehner, A
   Mueller-Seubert, W
   Cai, AJ
   Arkudas, A
   Ludolph, I
AF Gruener, Jasmin S.
   Horch, Raymund E.
   Geierlehner, Alexander
   Mueller-Seubert, Wibke
   Cai, Aijia
   Arkudas, Andreas
   Ludolph, Ingo
TI Is Instillational Topical Negative Pressure Wound Therapy in
   Peri-Prosthetic Infections of the Breast Effective? A Pilot Study
SO JOURNAL OF PERSONALIZED MEDICINE
LA English
DT Article
DE breast infection; peri-prosthetic infection; breast implant infection;
   silicone prostheses; negative pressure wound therapy; instillation
ID VACUUM-ASSISTED CLOSURE; TISSUE EXPANDER; IMPLANT; RECONSTRUCTION;
   SALVAGE; MANAGEMENT; HIP; COMPLICATIONS; SURGERY; DEVICE
AB Peri-prosthetic breast infections pose a risk of severe complications after breast implant surgery. The need to remove the breast implant, control the infection and perform additional surgical procedures are the consequences. Reimplantation of an alloplastic implant is only appropriate after an infection-free interval. In this retrospective cohort study, we investigated the effectiveness of negative pressure wound treatment with instillation and dwell time (NPWTi-d) on peri-prosthetic breast infections in combination with implant removal and antibiotic therapy. Twelve patients treated with NPWTi-d due to breast implant infection were included in the study. The bacterial burden was analyzed using wound swabs before and after NPWTi-d. Additionally, laboratory values were determined before NPWTi-d and immediately before wound closure. A total of 13 peri-prosthetic breast infections in 12 patients were treated using implant removal and NPWTi-d. In 76.9% (n = 10) of the cases, the patients had undergone alloplastic breast reconstruction following cancer-related mastectomy, whereas 23.1% (n = 3) of the patients had undergone breast augmentation for cosmetic reasons. The bacterial burden in the breast pocket decreased statistically significant after implant removal and NPWTi-d. No shift from Gram-positive to Gram-negative bacteria was observed. Inflammatory markers rapidly decreased following treatment. NPWTi-d had a positive impact on the healing process after peri-prosthetic breast infections, leading to a decrease in bacterial burden within the wounds and contributing to uneventful healing. Therefore, secondary reimplantation of breast prostheses might be positively influenced when compared to conventional implant removal and simple secondary closure. Further studies are required to conclusively establish the beneficial long-term effects of using NPWTi-d for the treatment of peri-prosthetic breast infections.
C1 [Gruener, Jasmin S.; Horch, Raymund E.; Geierlehner, Alexander; Mueller-Seubert, Wibke; Cai, Aijia; Arkudas, Andreas; Ludolph, Ingo] Friedrich Alexander Univ Erlangen Nurnberg FAU, Univ Hosp Erlangen, Dept Plast & Hand Surg, Lab Tissue Engn & Regenerat Med, D-91054 Erlangen, Germany.
C3 University of Erlangen Nuremberg
RP Gruener, JS (通讯作者)，Friedrich Alexander Univ Erlangen Nurnberg FAU, Univ Hosp Erlangen, Dept Plast & Hand Surg, Lab Tissue Engn & Regenerat Med, D-91054 Erlangen, Germany.
EM jasmin.gruener@uk-erlangen.de
RI Horch, Raymund E/H-8128-2019; Arkudas, Andreas/AAQ-6745-2021; Cai,
   Aijia/JXN-8479-2024; Grüner, Jasmin/ABF-2976-2021
OI Horch, Raymund E/0000-0002-6561-2353; Arkudas,
   Andreas/0000-0002-2473-5816; Barth, Jasmin S/0000-0002-8033-7644;
   Ludolph, Ingo/0000-0003-4806-7717; Cai, Aijia/0000-0001-8738-9298; 
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NR 51
TC 11
Z9 11
U1 1
U2 4
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
EI 2075-4426
J9 J PERS MED
JI J. Pers. Med.
PD DEC
PY 2022
VL 12
IS 12
AR 2054
DI 10.3390/jpm12122054
PG 12
WC Health Care Sciences & Services; Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services; General & Internal Medicine
GA 7E2ZB
UT WOS:000901041700001
PM 36556274
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Seidel, D
   Lefering, R
AF Seidel, Doerthe
   Lefering, Rolf
CA DiaFu Study Grp
TI NPWT resource use compared with standard moist wound care in diabetic
   foot wounds: DiaFu randomized clinical trial results
SO JOURNAL OF FOOT AND ANKLE RESEARCH
LA English
DT Article
DE Negative pressure wound therapy; Diabetic foot; Wound care; Wound;
   Resource use
ID VACUUM-ASSISTED CLOSURE; THERAPY; ULCERS; MULTICENTER
AB Background: Diabetic foot ulcers not only have a negative impact on patient mortality, morbidity and quality of life, but also require high resource utilization to achieve complete wound healing. The aim of this evaluation was to compare resource utilization of negative pressure wound therapy (NPWT) and standard moist wound care (SMWC) for diabetic foot wounds after amputation, surgical debridement or wound cleansing.
   Methods: The multicenter clinical DiaFu study enrolled 368 adults with diabetic foot ulcers between December 23, 2011 and October 21, 2014. Patients were randomly assigned to NPWT and SMWC. Evaluation of direct resource use comprised inpatient and outpatient treatment time, and personnel and material for wound treatment within 16 weeks. This resource use analysis was primarily based on the per protocol population (NPWT 44; SMWC 110).
   Results: Treatment duration was 16 days shorter with NPWT (mean (SD) 82.8 (31.6), SMWC 98.8 (24.6); U test, p = 0.001) with 14.9 days shorter outpatient treatment (mean (SD) NPWT 68.3 (31.1), SMWC 83.2 (29.7)). The number of dressing changes per study participant was lower with NPWT (mean (SD) 35.1 (18.6), SMWC (42.9 (21.4); U test, p = 0.067). Time per dressing change was significantly lower with SMWC (mean (SD) 19.7 (12.8), NPWT (16.5 (8.2) minutes; U test, p < < 0.0001). Time for surgical debridements per study participant was 23.3 minutes shorter with NPWT (mean (SD) 20.5 (20.5), SMWC (43.8 (46.7); U test, p = 0.395).
   Conclusions: Resource use was lower for NPWT, which may be an efficient treatment alternative to SMWC for diabetic foot wounds, to be demonstrated in subsequent cost analyses.
C1 [Seidel, Doerthe; Lefering, Rolf; DiaFu Study Grp] Univ Witten Herdecke, Inst Forsch Operativen Med IFOM, Ostmerheimerstr 200 Haus 38, D-51109 Cologne, Germany.
C3 Witten Herdecke University
RP Seidel, D (通讯作者)，Univ Witten Herdecke, Inst Forsch Operativen Med IFOM, Ostmerheimerstr 200 Haus 38, D-51109 Cologne, Germany.
EM DoertheSeidel@gmx.de
OI Lefering, Rolf/0000-0002-0141-1747
FU Projekt DEAL
FX Open Access funding enabled and organized by Projekt DEAL. Through a
   European tender, the study was initiated by a consortium of 19 statutory
   German health insurance funds, which provided integrated care contracts
   for all study participants and for up to 7000 patients with acute and
   chronic wounds in Germany, defined basic rules for study design based on
   the requirements of the German authorities; and provided a critical
   review of the study protocol and the final report. The study was funded
   by the manufacturers KCI (Acelity) and S&N. Both companies provided the
   NPWT devices and associated consumable supplies in the assigned regions
   of Germany as well as all necessary support and information about the
   used material. The manufacturers had no role in study design, data
   collection, data analysis, data interpretation or writing of the report.
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NR 26
TC 20
Z9 22
U1 4
U2 22
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
EI 1757-1146
J9 J FOOT ANKLE RES
JI J. Foot Ankle Res.
PD SEP 30
PY 2022
VL 15
IS 1
AR 72
DI 10.1186/s13047-022-00569-w
PG 14
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 4Z7WQ
UT WOS:000862414300001
PM 36180953
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Patel, BJ
   Asher, CM
   Bystrzonowski, N
   Healy, C
AF Patel, Benjamin J.
   Asher, Christian M.
   Bystrzonowski, Nicola
   Healy, Ciaran
TI Safeguarding Skin Grafts An Evidence-Based Summary of Fixation
   Techniques
SO ANNALS OF PLASTIC SURGERY
LA English
DT Review
DE skin graft; plastic surgery; fibrin glue; tie-over bolster; negative
   pressure wound therapy
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; RANDOMIZED
   CONTROLLED-TRIAL; OVER BOLSTER DRESSINGS; FIBRIN SEALANT; BURN WOUNDS;
   THICKNESS; EFFICACY; DEVICE; GLUE
AB Background Effective skin graft fixation is vital in preventing sheering forces, seroma, and hematoma from compromising graft take. Yet, selecting the ideal technique for securing skin grafts remains a contentious subject, with significant variation in practice existing between surgeons. There is, therefore, benefit to be derived from assessing the literature for evidence-based recommendations to guide the decision-making process. Methods A search of Medline and Embase was performed using appropriate key terms, yielding 419 articles. Reference lists were analyzed. Inclusion and exclusion criteria were composed. Level I to III studies, as defined by the Centre for Evidence-Based Medicine, that compared skin graft fixation methods were analyzed. Rayyan QCRI was used for abstract and title screening. After full text screening, 41 studies were included for qualitative analysis. All included randomized control trials (RCTs) were assessed for risk of bias using the Cochrane Risk-of-Bias 2 (ROB2) tool. Results We identified 4 groups of fixation technique: "tie-over bolster" (TOB), "no TOB," "adhesive glues," and "negative pressure wound therapy" (NPWT). Twelve studies compared TOB with no TOB, with no difference in graft take demonstrated. Sixteen studies compared adhesive glues with traditional methods, with no difference in graft take demonstrated. Thirteen studies compared NPWT with traditional methods, with enhanced graft take demonstrated. Risk of bias was deemed low in 1 of 13 RCTs. Conclusions Based on the current evidence, only NPWT is associated with enhanced graft take. However, there is a scarcity of robust level I evidence comparing different fixation techniques, meaning that strong recommendations cannot be made. We propose examples of hypothesis-driven RCTs, in predetermined clinical settings, based on the theoretical benefits of the techniques that would add value to clinical practice.
C1 [Patel, Benjamin J.; Asher, Christian M.; Bystrzonowski, Nicola; Healy, Ciaran] Guys & St Thomas NHS Fdn Trust, Dept Plast Surg, London, England.
C3 Guy's & St Thomas' NHS Foundation Trust
RP Patel, BJ (通讯作者)，Southmead Hosp, Southmead Rd, Bristol BS10 5NB, Avon, England.
EM benjpatel@gmail.com
RI Asher, Christian/AAK-5121-2020
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NR 69
TC 7
Z9 7
U1 1
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD DEC
PY 2021
VL 87
IS 6
BP E180
EP E188
DI 10.1097/SAP.0000000000002937
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA XC4HA
UT WOS:000721974600009
PM 34117134
DA 2026-07-24
ER

PT J
AU Zwanenburg, PR
   Tol, BT
   Obdeijn, MC
   Lapid, O
   Gans, SL
   Boermeester, MA
AF Zwanenburg, Pieter R.
   Tol, Berend T.
   Obdeijn, Miryam C.
   Lapid, Oren
   Gans, Sarah L.
   Boermeester, Marja A.
TI Meta-analysis, Meta-regression, and GRADE Assessment of Randomized and
   Nonrandomized Studies of Incisional Negative Pressure Wound Therapy
   Versus Control Dressings for the Prevention of Postoperative Wound
   Complications
SO ANNALS OF SURGERY
LA English
DT Article
DE hematoma; incision; necrosis; negative pressure wound therapy;
   prevention; seroma; surgical site infection; surgical wound; wound care;
   wound dehiscence
ID SURGICAL-SITE INFECTIONS; VACUUM-ASSISTED CLOSURE; HIGH-RISK PATIENTS;
   MAJOR MUSCLE FLAP; VASCULAR-SURGERY; MANAGEMENT-SYSTEM; OBESE-PATIENTS;
   LAPAROTOMY INCISIONS; CESAREAN DELIVERY; CLOSED INCISIONS
AB Objective: The aim of this study was to evaluate the efficacy of iNPWT for the prevention of postoperative wound complications such as SSI. Summary of Background Data: The 2016 WHO recommendation on the use of iNPWT for the prevention of SSI is based on low-level evidence, and many trials have been published since. Preclinical evidence suggests that iNPWT may also prevent wound dehiscence, skin necrosis, seroma, and hematoma. Methods: PubMed, EMBASE, CINAHL, and CENTRAL were searched for randomized and nonrandomized studies that compared iNPWT with control dressings. The evidence was assessed using the Cochrane Risk of Bias Tool, the Newcastle-Ottawa scale, and GRADE. Meta-analyses were performed using random-effects models. Results: High level evidence indicated that iNPWT reduced SSI [28 RCTs, n = 4398, relative risk (RR) 0.61, 95% confidence interval [CI]: 0.49-0.76,P< 0.0001,I-2= 27%] with a number needed to treat of 19. Low level evidence indicated that iNPWT reduced wound dehiscence (16 RCTs, n = 3058, RR 0.78, 95% CI: 0.64-0.94). Very low-level evidence indicated that iNPWT also reduced skin necrosis (RR 0.49, 95% CI: 0.33-0.74), seroma (RR 0.43, 95% CI: 0.32-0.59), and length of stay (pooled mean difference -2.01, 95% CI: -2.99 to 1.14). Conclusions: High-level evidence indicates that incisional iNPWT reduces the risk of SSI with limited heterogeneity. Low to very low-level evidence indicates that iNPWT also reduces the risk of wound dehiscence, skin necrosis, and seroma.
C1 [Zwanenburg, Pieter R.; Tol, Berend T.; Gans, Sarah L.; Boermeester, Marja A.] Univ Amsterdam, Dept Surg Amsterdam Gastroenterol & Metab, Amsterdam Infect & Immun, Amsterdam UMC, Amsterdam, Netherlands.
   [Obdeijn, Miryam C.; Lapid, Oren] Univ Amsterdam, Dept Plast Reconstruct & Hand Surg, Amsterdam UMC, Amsterdam, Netherlands.
C3 University of Amsterdam; University of Amsterdam
RP Boermeester, MA (通讯作者)，Univ Amsterdam, Dept Surg Amsterdam Gastroenterol & Metab, Amsterdam Infect & Immun, Amsterdam UMC, Amsterdam, Netherlands.
EM m.a.boermeester@amc.nl
RI ; Lapid, Oren/S-6331-2019
OI Boermeester, Marja/0000-0003-3890-8105; Lapid, Oren/0000-0001-8921-9866
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NR 141
TC 56
Z9 58
U1 0
U2 15
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0003-4932
EI 1528-1140
J9 ANN SURG
JI Ann. Surg.
PD JUL
PY 2020
VL 272
IS 1
BP 81
EP 91
DI 10.1097/SLA.0000000000003644
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA NN6KR
UT WOS:000568895500030
PM 31592899
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Shin, SJ
   Han, D
   Song, H
   Jang, YJ
   Park, DH
   Park, MC
AF Shin, Seung Jun
   Han, DaeHee
   Song, Hyunsuk
   Jang, Yu Jin
   Park, Dong Ha
   Park, Myong Chul
TI Continuous High-Pressure Negative Suction Drain: New Powerful Tool for
   Closed Wound Management: Clinical Experience
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Seroma; wall suction; continuous high-pressure negative suction drain
ID VACUUM-ASSISTED CLOSURE; THERAPY; SKIN
AB Background: Although various reconstructive flap surgeries have been successfully performed, there still are difficult wound complications, such as seroma formation, wound margin necrosis, delayed wound healing, and even flap failures. The negative-pressure wound therapy has been described in detail in the literature to assist open chronic/complex wound closure in reconstructive surgery. However, the negative-pressure wound therapy was difficult to be applied under the incisional closed wounds.
   Methods: A total of 23 patients underwent the various reconstructive flap surgeries with continuous high-pressure negative suction drain. Instead of using regular suction units, Barovac (50-90 mm Hg, Sewoon Medical, Seoul, Republic of Korea) drainage tubes were connected to the wall suction unit, providing continuous high-powered negative pressure. In addition, continuous subatmospheric suction pressure (100-300 mm Hg) was applied. Outcome of the measures was obtained from the incidence of seroma, volume of postoperative drainage, hospitalization period, and incidence of other typical wound complications. Dead space was evaluated postoperatively with ultrasonography.
   Results: Using continuous high-pressure negative suction drain, successful management of seroma was obtained without any major complication such as wound infection, flap loss, and wound margin necrosis, except for only 1 case of seroma after discharge from the hospital. The indwelling time of the drain in the latissimus dorsi donor site was significantly reduced in comparison with the authors' previous data (P = 0.047). The volume of drainage and hospitalization period were also reduced; however, these were not statistically significant. The dead space with continuous high-pressure negative suction drain was more reduced than in the control group in the immediate postoperative period and confirmed with ultrasonography.
   Conclusions: Continuous high-pressure negative suction drain might be the simple and powerful solution in the management of challenging closed wounds.
C1 [Shin, Seung Jun; Han, DaeHee; Song, Hyunsuk; Jang, Yu Jin; Park, Dong Ha; Park, Myong Chul] Ajou Univ Hosp, Dept Plast & Reconstruct Surg, Suwon 443721, Gyeonggi Do, South Korea.
C3 Ajou University; Ajou University Hospital
RP Park, MC (通讯作者)，Ajou Univ Hosp, Dept Plast & Reconstruct Surg, Suwon 443721, Gyeonggi Do, South Korea.
EM mpark@ajou.ac.kr
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NR 15
TC 6
Z9 10
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD JUL
PY 2014
VL 25
IS 4
BP 1427
EP 1431
DI 10.1097/SCS.0000000000000575
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AN0EZ
UT WOS:000340257800116
PM 24905942
DA 2026-07-24
ER

PT J
AU Ho, CH
   Powell, HL
   Collins, JF
   Bauman, WA
   Spungen, AM
AF Ho, Chester H.
   Powell, Heather L.
   Collins, Joseph F.
   Bauman, William A.
   Spungen, Ann M.
TI Poor Nutrition Is a Relative Contraindication to Negative Pressure Wound
   Therapy for Pressure Ulcers: Preliminary Observations in Patients with
   Spinal Cord Injury
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; PREVALENCE
AB OBJECTIVE: To assess the efficacy of negative-pressure wound therapy (NPWT) for healing of pressure ulcers (PrUs) in individuals with spinal-cord injury (SCI).
   DESIGN: Multicenter, 28-day observational study.
   SETTING: Ten Veterans Affairs Medical Center SCI centers.
   PATIENTS: Eighty-six SCI inpatients with Stage III/IV pelvic PrUs.
   INTERVENTIONS: Standard wound care with NPWT versus standard wound care alone (NoNPWT).
   MAIN OUTCOME MEASURES: Change in wound surface area (WSA) using the Verg Videometer Measurement Documentation software.
   MAIN RESULTS: The proportion of patients demonstrating a decrease in WSA (healing subgroup) was not significantly different between the NPWT (n = 33) and NoNPWT (n = 53) groups (67% vs 70%, respectively). In the healing subgroup, there was no significant difference between the NPWT versus NoNPWT groups in WSA decrease (-43 +/- 22% vs -50% +/- 26%, not statistically significant). Similarly, in the nonhealing subgroup, there was no significant difference between NPWT and NoNPWT groups (31% +/- 26% vs 32% +/- 34%). In the NPWT group, the nonhealing subgroup (11/33) had significantly lower serum albumin levels than the healing subgroup (22/33) (2.9 +/- 0.4 vs 3.3 +/- 0.5 mg/dL, P < .05). In the NoNPWT group, there was no significant difference in serum albumin levels between the healing versus nonhealing subgroups (3.2 +/- 0.3 vs 3.2 +/- 0.3 mg/dL).
   CONCLUSION: In SCI patients with Stage III/IV pelvic PrUs, NPWT did not significantly influence the rate of healing. Additionally, in malnourished individuals (albumin <3.0 mg/dL), NPWT was not efficacious. Healing outcomes in the NPWT group were significantly influenced by albumin levels, whereas no such disparity was noted between the healing and nonhealing PrUs for the NoNPWT group. Nutritional status appears to be important in the effectiveness of NPWT.
C1 [Ho, Chester H.; Powell, Heather L.] Louis Stokes Cleveland Dept Vet Affairs Med Ctr, Cleveland, OH USA.
   [Ho, Chester H.; Powell, Heather L.] Case Western Reserve Univ, Dept Phys Med & Rehabil, Cleveland, OH 44106 USA.
   [Collins, Joseph F.] VA Med Ctr, Cooperat Studies Program Coordinating Ctr, Perry Point, MD USA.
   [Bauman, William A.; Spungen, Ann M.] James J Peters VA Med Ctr, RR&D Ctr Excellence Med Consequences Spinal Cord, Bronx, NY USA.
   [Bauman, William A.; Spungen, Ann M.] Mt Sinai Sch Med, Dept Med, New York, NY USA.
   [Bauman, William A.; Spungen, Ann M.] Mt Sinai Sch Med, Dept Rehabil Med, New York, NY USA.
C3 University System of Ohio; Case Western Reserve University; US
   Department of Veterans Affairs; Veterans Health Administration (VHA);
   Louis Stokes Cleveland Veterans Affairs Medical Center; University
   System of Ohio; Case Western Reserve University; US Department of
   Veterans Affairs; Veterans Health Administration (VHA); James J. Peters
   VA Medical Center; Icahn School of Medicine at Mount Sinai; Icahn School
   of Medicine at Mount Sinai
RI ; Collins, Joe/LBH-9523-2024
OI Ho, Chester/0000-0002-4238-5506; 
FU Department of Veterans Affairs, VA Office of Research and Development,
   Clinical Sciences Service [535]; SCI Service and Rehabilitation Research
   and Development Center of Excellence for the Medical Consequences of
   SCI, VA Medical Center, Bronx, New York [B4162C]
FX Funding for this study was provided by the Department of Veterans
   Affairs, VA Office of Research and Development, Clinical Sciences
   Service, Cooperative Studies Program, CS #535; SCI Service and
   Rehabilitation Research and Development Center of Excellence for the
   Medical Consequences of SCI #B4162C, James J. Peters VA Medical Center,
   Bronx, New York. The authors acknowledge Dr William Krol, as well as the
   following participating sites and site investigators for their effort
   and participation in this project: Charlie Norwood VA Medical Center
   (Augusta, Georgia)-Rose C. Trincher, MD; James J. Peters VA Medical
   Center (Bronx, New York)-George A. Deitrick, MD; Louis Stokes VA Medical
   Center (Cleveland, Ohio)-Chester H. Ho, MD; VA North Texas Healthcare
   System: Dallas VA Medical Center-Lance L. Goetz, MD; Edward Hines Jr VA
   Hospital (Hines, Illinois)-Bernard A. Nemchausky, MD; Michael E. Debakey
   VA Medical Center (Houston, Texas)-Sally A. Holmes, MD; VA Palo Alto
   Health Care System (Palo Alto, California)-Roy Sasaki, MD; Hunter Holmes
   McGuire VA Medical Center (Richmond, Virginia)-Meena Midha, MD; James A.
   Haley Veterans' Hospital (Tampa, Florida)-John L. Merritt, MD; and VA
   Boston Healthcare System, West Roxbury Campus (Boston,
   Massachusetts)-Sunil Sabharwal, MD.
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NR 21
TC 17
Z9 19
U1 0
U2 11
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD NOV
PY 2010
VL 23
IS 11
BP 508
EP 516
DI 10.1097/01.ASW.0000390493.43835.ec
PG 9
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA 832ZF
UT WOS:000295849100004
PM 20975334
DA 2026-07-24
ER

PT J
AU Matsumine, H
   Giatsidis, G
   Fujimaki, H
   Yoshimoto, N
   Makino, Y
   Hosoi, S
   Takagi, M
   Shimizu, M
   Takeuchi, M
AF Matsumine, Hajime
   Giatsidis, Giorgio
   Fujimaki, Hiroshi
   Yoshimoto, Nobuyuki
   Makino, Yuma
   Hosoi, Satoshi
   Takagi, Mika
   Shimizu, Mari
   Takeuchi, Masaki
TI NPWTi allows safe delayed free flap repair of Gustilo IIIb injuries: A
   prospective case series
SO REGENERATIVE THERAPY
LA English
DT Letter
DE Free flap; Microsurgery; Lower extremity; Negative Pressure Wound
   Therapy; NPWTi
ID PRESSURE WOUND THERAPY; VACUUM-ASSISTED CLOSURE; SOFT-TISSUE COVERAGE;
   OPEN FRACTURES; EXTREMITY FRACTURES; ANTISEPTIC SOLUTION; INSTILLATION;
   MANAGEMENT; INFECTION; SALINE
AB Introduction: Free flap lower extremity repair is associated with a high complication rate (>31%); higher rates are observed in more severe patients. In cases requiring prior systemic/local stabilization, delayed repair increases complication rate (thorn10% at 7 days): Negative-pressure Wound Therapy (NPWT) decreases complications but only when applied for less than 7 days. Recent limited evidence suggests that augmentation of NPWT with instillation for wound irrigation (NPWTi) might safely extend such window. This study hypothesizes that, through the combined cleansing effect of NPWT and instillation, NPWTi allows safe (low complication rate) delayed free flap repair in severe patients with Gustilo IIIb injuries (GIIIb).
   Methods: A prospective case series was designed (inclusion criteria: GIIIb requiring microsurgical repair, severe patient/injury condition preventing immediate/early repair; exclusion criteria: allergy to NPWTi dressing). Patients received NPWTi (suction: 125 mmHg continuous; irrigation: NaCl 0.9%) until considered clinically ready for repair. Preoperative/postoperative complications (dehiscence, wound infection, bone non-union, osteomyelitis, flap failure) were monitored with clinical signs, imaging, and serum markers (CRP, WBC).
   Results: Four patients (male: N = 4, female N = 1; Age: 59 [44-75] years-old) were treated. NPWTi was applied for 15.2 [9-28] days. No complication (0%) was observed preoperatively or postoperatively. Delayed repair occurred by latissimus dorsi musculocutaneous flap (N = 3), and anterolateral thigh flap (N = 2). All patients walked weight-bearing 12 [6-20] weeks after injury.
   Conclusions: NPWTi seems to allow safe delayed free flap repair in patients with severe lower extremity injuries unable to undergo immediate/early repair. (C) 2021, The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V.
C1 [Matsumine, Hajime; Fujimaki, Hiroshi; Makino, Yuma; Hosoi, Satoshi; Takagi, Mika; Shimizu, Mari; Takeuchi, Masaki] Tokyo Womens Med Univ, Yachiyo Med Ctr, Dept Plast & Reconstruct Surg, 477-96 Owada Shinden, Yachiyo, Chiba 2768524, Japan.
   [Giatsidis, Giorgio] Univ Massachusetts, Sch Med, Div Plast Surg, Worcester, MA 01655 USA.
   [Yoshimoto, Nobuyuki] Tokyo Womens Med Univ, Yachiyo Med Ctr, Dept Orthoped, Yachiyo, Chiba 2768524, Japan.
C3 Tokyo Women's Medical University; University of Massachusetts System;
   University of Massachusetts Worcester; Tokyo Women's Medical University
RP Matsumine, H (通讯作者)，Tokyo Womens Med Univ, Yachiyo Med Ctr, Dept Plast & Reconstruct Surg, 477-96 Owada Shinden, Yachiyo, Chiba 2768524, Japan.
EM matsumine.hajime@twmu.ac.jp
RI ; /M-9982-2013; Matsumine, Hajime/ITW-3111-2023; Giatsidis,
   Giorgio/B-4950-2013
OI Fujiamki, Hiroshi/0009-0003-2109-1829; 
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NR 55
TC 2
Z9 4
U1 0
U2 9
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 2352-3204
J9 REGEN THER
JI Regen. Ther.
PD DEC
PY 2021
VL 18
BP 82
EP 87
DI 10.1016/j.reth.2021.04.001
PG 6
WC Cell & Tissue Engineering; Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Engineering
GA WA7TW
UT WOS:000703088900012
PM 33997186
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Steen, EH
   Wang, XY
   Boochoon, KS
   Ewing, DC
   Strang, HE
   Kaul, A
   Masri, L
   Balaji, S
   Hollier, LH 
   Keswani, S
AF Steen, Emily H.
   Wang, Xinyi
   Boochoon, Kieran S.
   Ewing, Donald C.
   Strang, Harrison E.
   Kaul, Aditya
   Masri, Leighanne
   Balaji, Swathi
   Hollier, Larry H., Jr.
   Keswani, Sundeep
TI Wound Healing and Wound Care in Neonates: Current Therapies and Novel
   Options
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
DE alginate; adhesive; collagen dressing; foam; hydrocolloid; hydrogel;
   moisture-associated skin damage; negative-pressure wound therapy;
   neonate; wound healing
ID VACUUM-ASSISTED CLOSURE; MANAGEMENT; PRESSURE; HYDROGEL; SKIN
AB GENERAL PURPOSE To provide wound care information that considers the specific physiology of neonates.
   TARGET AUDIENCE This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.
   LEARNING OBJECTIVES/OUTCOMES After participating in this educational activity, the participant will: 1. Differentiate the use of hydrocolloids, hydrogels, foam dressings, and barrier creams in the neonatal population. 2. Identify issues related to the use of solvents, alginates, collagen dressings, and negative-pressure wound therapy in neonates.
   ABSTRACT
   OBJECTIVE To discuss what is known about the wound milieu in premature and full-term neonates, including the unique challenges pediatric clinicians face, the therapies that have proven effective, and the therapies contraindicated for use in neonatal wound healing to guide treatment that accounts for the specific physiological characteristics of this often overlooked population.
   DATA SOURCES Data were collected on neonatal wound healing from a wide variety of sources, including PubMed, Google Scholar, journals, and textbooks.
   STUDY SELECTION Selection criteria included publications focused on the differences and nuances of wound healing in neonates in comparison with all other age groups.
   DATA EXTRACTION Data were extracted based on articles covering wound healing therapies with proven effectiveness in neonates. Terms for neonatal wound care were compiled, and then a comprehensive literature search was performed by the authors.
   DATA SYNTHESIS Although many therapies are safe for treatment of older children and adolescents, most have not been explicitly tested for neonatal use. This article reviews therapies with proven effectiveness and/or specific concerns in the neonatal population.
   CONCLUSION This review sheds light on the advantages and disadvantages of current standards of care regarding wound healing for neonates to direct researchers and clinicians toward developing treatments specifically for this delicate population.
C1 [Steen, Emily H.] Baylor Coll Med, Dept Surg, Houston, TX 77030 USA.
   [Wang, Xinyi; Strang, Harrison E.; Kaul, Aditya; Masri, Leighanne; Balaji, Swathi] Texas Childrens Hosp, Dept Surg, Lab Regenerat Tissue Repair, Houston, TX 77030 USA.
   [Boochoon, Kieran S.; Ewing, Donald C.] Texas A&M Coll Med, Bryan, TX USA.
   [Hollier, Larry H., Jr.; Keswani, Sundeep] Baylor Coll Med, Houston, TX 77030 USA.
   [Hollier, Larry H., Jr.; Keswani, Sundeep] Texas Childrens Hosp, Dept Surg, Div Plast Surg, Houston, TX 77030 USA.
C3 Baylor College of Medicine; Baylor College of Medicine; Baylor College
   Medical Hospital; Texas A&M University System; Texas A&M University
   College Station; Texas A&M Health Science Center; Baylor College of
   Medicine; Baylor College of Medicine; Baylor College Medical Hospital
RP Steen, EH (通讯作者)，Baylor Coll Med, Dept Surg, Houston, TX 77030 USA.
RI Wang, Xinyi/AAN-4271-2020
OI Wang, Xinyi/0000-0003-1780-7719
FU National Institute of General Medical Sciences [R01GM111808] Funding
   Source: NIH RePORTER
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NR 30
TC 14
Z9 23
U1 0
U2 25
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD JUN
PY 2020
VL 33
IS 6
BP 294
EP 300
DI 10.1097/01.ASW.0000661804.09496.8c
PG 7
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA LT5MB
UT WOS:000537113600005
PM 32427785
DA 2026-07-24
ER

PT J
AU Malmsjö, M
   Ingemansson, R
AF Malmsjo, Malin
   Ingemansson, Richard
TI Effects of green foam, black foam and gauze on contraction, blood flow
   and pressure delivery to the wound bed in negative pressure wound
   therapy
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article
DE Experimental surgery; Wound healing; Negative pressure; wound therapy;
   Wound contraction; Blood flow; Wound dressing
ID VACUUM-ASSISTED CLOSURE; PERISTERNAL THORACIC WALL; MATRIX
   METALLOPROTEINASES
AB Background: Negative pressure wound therapy (NPWT) contracts the wound and alters the microvascular blood flow in the wound edge, which may be crucial in promoting wound healing. The aim of the present study was to examine these biological effects in the wound edge using different types of wound fillers.
   Methods: Wounds were created on the backs of pigs and filled with green foam, black foam or gauze. Dressings for NPWT were then applied. The immediate effects of continuous NPWT, including pressure transmission to the wound bed and microvascular blood flow (using laser Doppler velocimetry), were studied in eight pigs that were anaesthetised for 12 h. In another eight pigs, wound contraction was studied during 72 h of NPWT.
   Results: Pressure transduction to the wound bed was similar through green foam, black foam and gauze, with only small pressure drop. Wound contraction was more pronounced for green and black foam than for gauze. Blood flow was found to decrease 0.5 cm from the wound edge and increase 2.5 cm from the wound edge. The increase in blood flow was similar with all wound fillers, while the decrease was less pronounced with gauze than with both foams.
   Conclusions: The biological effects of NPWT depend on the type of wound filler. Green and black foam have similar effects, while gauze results in less pronounced wound contraction and hypoperfusion. NPWT may be tailored to the individual wound type to optimise the effects and minimise the complications by choosing different wound fillers. (C) 2011 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Malmsjo, Malin] Lund Univ, Dept Ophthalmol, Lund, Sweden.
   [Malmsjo, Malin; Ingemansson, Richard] Skane Univ Hosp, Lund, Sweden.
   [Ingemansson, Richard] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
C3 Lund University; Lund University; Skane University Hospital; Lund
   University
RP Malmsjö, M (通讯作者)，BMC A13, SE-22184 Lund, Sweden.
EM malin.malmsjo@med.lu.se
OI Ingemansson, Richard/0000-0001-7623-8953; Maljö,
   Malin/0000-0001-9849-9599
FU Molnlycke Health Care AB
FX Molnlycke Health Care AB.
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NR 37
TC 16
Z9 19
U1 0
U2 10
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD DEC
PY 2011
VL 64
IS 12
BP E289
EP E296
DI 10.1016/j.bjps.2011.06.023
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 847GC
UT WOS:000296959000001
PM 21788163
DA 2026-07-24
ER

PT J
AU Driver, VR
   Blume, PA
AF Driver, Vickie R.
   Blume, Peter A.
TI Evaluation of Wound Care and Health-Care Use Costs in Patients with
   Diabetic Foot Ulcers Treated with Negative Pressure Wound Therapy versus
   Advanced Moist Wound Therapy
SO JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MULTICENTER; IMPACT
AB Background: We conducted a post-hoc retrospective analysis of patients enrolled in a randomized controlled trial to evaluate overall costs of negative pressure wound therapy (NPWT; V.A.C. Therapy; KCI USA, Inc, San Antonio, Texas) versus advanced moist wound therapy (AMWT) in treating grade 2 and 3 diabetic foot wounds during a 12-week therapy course.
   Methods: Data from two study arms (NPWT [n = 169] or AMWT [n = 166]) originating from Protocol VAC2001-08 were collected from patient records and used as the basis of the calculations performed in our cost analysis.
   Results: A total of 324 patient records (NPWT = 162; AMWT = 162) were analyzed. There was a median wound area reduction of 85.0% from baseline in patients treated with NPWT compared to a 61.8% reduction in those treated with AMWT. The total cost for all patients, regardless of closure, was $1,941,472.07 in the NPWT group compared to $2,196,315.86 in the AMWT group. In patients who achieved complete wound closure, the mean cost per patient in the NPWT group was $10,172 compared to $9,505 in the AMWT group; the median cost per 1 cm(2) of closure was $1,227 with NPWT and $1,695 with AMWT. In patients who did not achieve complete wound closure, the mean total wound care cost per patient in the NPWT group was $13,262, compared to $15,069 in the AMWT group. The median cost to close 1 cm2 in wounds that didn't heal using NPWT was $1,633, compared to $2,927 with AMWT.
   Conclusions: Our results show greater cost effectiveness with NPWT versus AMWT in recalcitrant wounds that didn't close during a 12-week period, due to lower expenditures on procedures and use of health-care resources.
C1 [Driver, Vickie R.] VA New England Hlth Care Div, Dept Surg, Providence, RI 02908 USA.
   [Blume, Peter A.] Yale Univ, Sch Med, Dept Anesthesiol, New Haven, CT 06510 USA.
C3 Yale University
RP Driver, VR (通讯作者)，VA New England Hlth Care Div, Dept Surg, 830 Chalkstone Ave, Providence, RI 02908 USA.
EM drvdriver@aol.com
CR [Anonymous], 3 C WORLD UN WOUND H
   [Anonymous], 2002, WOCN CLIN PRACTICE G, V1
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NR 27
TC 43
Z9 46
U1 1
U2 25
PU AMER PODIATRIC MED ASSOC
PI BETHESDA
PA 9312 OLD GEORGETOWN ROAD, BETHESDA, MD 20814-1621 USA
SN 8750-7315
EI 1930-8264
J9 J AM PODIAT MED ASSN
JI J. Am. Podiatr. Med. Assoc.
PD MAR-APR
PY 2014
VL 104
IS 2
BP 147
EP 153
DI 10.7547/0003-0538-104.2.147
PG 7
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA AI4QD
UT WOS:000336849000004
PM 24725034
DA 2026-07-24
ER

PT J
AU Steingrímsson, S
   Gustafsson, R
   Gudbjartsson, T
   Mokhtari, A
   Ingemansson, R
   Sjögren, J
AF Steingrimsson, Steinn
   Gustafsson, Ronny
   Gudbjartsson, Tomas
   Mokhtari, Arash
   Ingemansson, Richard
   Sjogren, Johan
TI Sternocutaneous Fistulas After Cardiac Surgery: Incidence and Late
   Outcome During a Ten-Year Follow-Up
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; STERNAL OSTEOMYELITIS; WOUND-INFECTION;
   STERNOTOMY; COMPLICATIONS; MEDIASTINITIS; MANAGEMENT
AB Background. Sternocutaneous fistulas (SCFs) after cardiac surgery represent a complex surgical problem involving multiple hospital admissions, prolonged antibiotic treatment, and repeated debridements. Our objective was to identify the incidence of and risk factors for SCF, and to evaluate long-term survival.
   Methods. A total of 12,297 patients underwent sternotomy for cardiac surgery between January 1999 and December 2008, and 32 patients were diagnosed as having SCF during follow-up. Risk factors were identified with multivariate analysis and survival was compared using the log-rank test.
   Results. The cumulative incidence of SCF at one year was 0.23%. There was no significant difference in mean time from sternal closure after cardiac surgery to intervention for SCF with (n = 9) or without (n = 23) preceding sternal wound infection (SWI); 6.1 +/- 4.2 versus 6.9 +/- 4.6 months, (p = ns). Risk factors for developing SCF were previous SWI (odds ratio [OR] = 15.7), renal failure (OR = 12.5), smoking (OR = 4.7), and use of bone wax during cardiac surgery (OR = 4.2). Negative-pressure wound therapy was applied in 20 cases of extensive SCFs. Five-year survival of SCF patients was 58% +/- 1% as compared with 85% +/- 4% in the control group (p = 0.003).
   Conclusions. Sternocutaneous fistula is a devastating diagnosis with significant morbidity and mortality. Previous SWI, renal failure, smoking, and use of bone wax are major risk factors. However, in a majority of patients SCF is not preceded by SWI and our results indicate that SCF may be a foreign body infection that develops in susceptible patients with risk factors for poor wound healing. Negative-pressure wound therapy may be a valuable adjunct in the treatment of extensive SCF. (Ann Thorac Surg 2009;88:1910-5) (C) 2009 by The Society of Thoracic Surgeons
C1 [Sjogren, Johan] Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, SE-22185 Lund, Sweden.
   Univ Iceland, Fac Med, Landspitali Univ Hosp, Dept Cardiothorac Surg, Reykjavik, Iceland.
C3 Lund University; Skane University Hospital; University of Iceland;
   Landspitali National University Hospital
RP Sjögren, J (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, SE-22185 Lund, Sweden.
EM johan.sjogren@med.lu.se
RI Steingrimsson, Steinn/AAF-5475-2021; Sjögren, Johan/AAZ-6448-2021
OI Steingrimsson, Steinn/0000-0001-8320-5607; Ingemansson,
   Richard/0000-0001-7623-8953; 
CR Darouiche RO, 2004, NEW ENGL J MED, V350, P1422, DOI 10.1056/NEJMra035415
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NR 16
TC 29
Z9 30
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD DEC
PY 2009
VL 88
IS 6
BP 1910
EP 1915
DI 10.1016/j.athoracsur.2009.07.012
PG 6
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 522VV
UT WOS:000272029100028
PM 19932261
DA 2026-07-24
ER

PT J
AU Fan, W
   Hou, FS
   Xi, K
   Hao, C
   Lu, XD
   Zhao, B
AF Fan, Wei
   Hou, Fushan
   Xi, Kun
   Hao, Chen
   Lu, Xiangdong
   Zhao, Bin
TI A filled chocolates technique to seal negative-pressure wound therapy
   around external fixation devices: a randomized controlled trial
SO JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE
AB Background: In complex injuries, external fixation device represents a challenge to maintain negative-pressure wound therapy (NPWT). In this trial, we compared a combination of bone wax and colostomy paste versus bone wax alone to seal NPWT around external fixation devices.
   Methods: Debridement surgeries of limbs with open fracture and large soft tissue defect need NPWT to be applied around the external fixation devices were randomized into two groups. The seal between external fixation devices and the drape was established using either bone wax first and then reinforced with colostomy paste or bone wax alone. The primary outcome was seal failure within 3 days of debridement. Secondary outcomes included the number of seal failure per debridement surgery and the time spent in repairing the seal within 3 days.
   Results: A total of 56 debridement surgeries were enrolled: 28 to the bone wax/colostomy paste group versus 28 to the bone wax control group. One patient in the control group died 1 day after the first debridement surgery. One patient in the bone wax/colostomy paste group was transferred to other hospitals within 3 days. The final analysis included 27 debridement surgeries in the bone wax/colostomy paste group and 27 debridement surgeries in the control group. The rate of seal failure (defined by loss of negative pressure at anytime within 3 days) was 81.5% (22/27) in the control group versus 11.1% (3/27) in the bone wax/colostomy paste group (p < 0.001; chi(2) test). The bone wax/colostomy paste group also had significantly lower number of seal failures per debridement (median of 0 vs. 2; p = 0.004), and shorter time spent in repairing the seal (median of 0 vs. 18 min; p < 0.001).
   Conclusions: Using bone wax followed by colostomy paste to seal NPWT around external fixation devices reduces seal failure.
C1 [Fan, Wei; Hou, Fushan; Hao, Chen; Lu, Xiangdong; Zhao, Bin] Shanxi Med Univ, Hosp 2, Dept Orthoped, 382 Wuyi Rd, Taiyuan 030001, Shanxi, Peoples R China.
   [Xi, Kun] Soochow Univ, Affiliated Hosp 1, Dept Orthoped, 188 Shizi Rd, Suzhou 215006, Jiangsu, Peoples R China.
C3 Shanxi Medical University; Soochow University - China
RP Lu, XD (通讯作者)，Shanxi Med Univ, Hosp 2, Dept Orthoped, 382 Wuyi Rd, Taiyuan 030001, Shanxi, Peoples R China.
EM luxiangdd@sohu.com; zzbb3737@163.com
RI Xi, Kun/JMQ-1169-2023
OI Xi, Kun/0000-0002-0458-9866; Hou, Fushan/0000-0002-7546-7890
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bulla A, 2014, J ORTHOP TRAUMA, V28, pE176, DOI 10.1097/BOT.0000000000000013
   Caputo GG, 2019, J ORTHOP TRAUMA, V33, pE24, DOI 10.1097/BOT.0000000000001281
   Hendricks N, 2014, OSTOMY WOUND MANAG, V60, P40
   Karadsheh Murad, 2017, Wounds, V29, pE106
   Karadsheh MJ, 2015, WOUNDS, V27, P244
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   Mannino BJ, 2017, J ORTHOP TRAUMA, V31, pE101, DOI 10.1097/BOT.0000000000000709
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   Yim GH, 2018, J BONE JOINT SURG AM, V100, DOI 10.2106/JBJS.18.00342
NR 12
TC 1
Z9 2
U1 0
U2 7
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-799X
J9 J ORTHOP SURG RES
JI J. Orthop. Surg. Res.
PD OCT 12
PY 2021
VL 16
IS 1
AR 587
DI 10.1186/s13018-021-02747-1
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA WG1AB
UT WOS:000706729800001
PM 34641918
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ridwan, S
   Grote, A
   Simon, M
AF Ridwan, Sami
   Grote, Alexander
   Simon, Matthias
TI Safety and Efficacy of Negative Pressure Wound Therapy for Deep Spinal
   Wound Infections After Dural Exposure, Durotomy, or Intradural Surgery
SO WORLD NEUROSURGERY
LA English
DT Article
DE Dura; NPWT; Revision surgery; Spinal surgery; Spinal infection; Spine;
   VAC
ID VACUUM-ASSISTED-CLOSURE; CEREBELLAR HEMORRHAGE; POSTOPERATIVE
   INFECTIONS; LUMBAR SPINE; RISK-FACTORS; MANAGEMENT; FUSION;
   INSTRUMENTATION; COMPLICATIONS; IRRIGATION
AB BACKGROUND: Negative pressure wound therapy (NPWT) for deep spinal wound infections after exposure or opening of the dura can carry significant risks (i.e., cerebrospinal fluid infections and fistulas). In the present study, we reviewed a fairly large and recent experience with such patients.
   METHODS: We identified 25 patients with exposure and/or incision of the dura who had undergone NPWT from January 2014 to June 2018 for deep spinal wound infections. The demographic data, specifics of primary surgery and NPWT (i.e., dressing changes, duration, time required for wound healing), patients' clinical course, outcomes, and microbiological findings were studied. Application of a Granufoam vacuum dressing with a continuous negative pressure of 60 mm Hg was performed after proper debridement.
   RESULTS: Of the 25 patients, 13 were women and 12 were men (median age, 69 years). They had primarily undergone treatment for spinal tumors (n = 7), infections and degenerative disease (n = 8 each), or fractures (n = 2), with instrumentation in 18 patients (72%). The dura was exposed in all 25 patients and had been incised in 10 (40%) patients (intended incision, 3; accidental incision, 7). Most patients had been treated for a lumbar wound infection (64%). A microorganism was detected in 84% of the cases, with Staphylococcus aureus accounting for most of the infections (48%). NPWT was concluded after a median of 4 dressing changes (range, 2-14) and 19 days (range, 10-70), with no implant removal required in any patient. NPWT application was observed to be safe without cerebrospinal fluid-related complications. The presence of comorbidities (28% had diabetes) had no effect on the treatment results.
   CONCLUSIONS: NPWT can be safely applied for deep spinal wound infections after dura exposure or durotomy during previous spine surgery.
C1 [Ridwan, Sami; Grote, Alexander; Simon, Matthias] Bethel Clin, Dept Neurosurg, Bielefeld, Germany.
RP Ridwan, S (通讯作者)，Bethel Clin, Dept Neurosurg, Bielefeld, Germany.
EM sami.ridwan@yahoo.de
RI Ridwan, Sami/U-9749-2019; Grote, Alexander/HLP-5518-2023
OI Ridwan, Sami/0000-0001-5103-9560; Grote, Alexander/0000-0002-6545-0622
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   Takai K, 2019, WORLD NEUROSURG, V121, pE700, DOI 10.1016/j.wneu.2018.09.193
   Tsubouchi N, 2018, EUR SPINE J, V27, P2481, DOI 10.1007/s00586-017-5294-1
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NR 43
TC 13
Z9 18
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1878-8750
EI 1878-8769
J9 WORLD NEUROSURG
JI World Neurosurg.
PD FEB
PY 2020
VL 134
BP E624
EP E630
DI 10.1016/j.wneu.2019.10.146
PG 7
WC Clinical Neurology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA KK6VS
UT WOS:000512878200076
PM 31678318
DA 2026-07-24
ER

PT J
AU Stinner, DJ
   Waterman, SM
   Masini, BD
   Wenke, JC
AF Stinner, Daniel J.
   Waterman, Scott M.
   Masini, Brendan D.
   Wenke, Joseph C.
TI Silver Dressings Augment the Ability of Negative Pressure Wound Therapy
   to Reduce Bacteria in a Contaminated Open Fracture Model
SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
LA English
DT Article; Proceedings Paper
CT 52nd Annual Meeting of the Society-of-Military-Orthopedic-Surgeons
   (SOMOS)
CY DEC 14-17, 2010
CL Vail, CO
SP Soc Mil Orthoped Surg
DE Contamination; Infection; Open fracture; Negative pressure; Silver
   dressing
ID VACUUM-ASSISTED CLOSURE
AB Background: Despite a lack of evidence supporting their use, silver dressings are often used with negative pressure wound therapy (NPWT). This study investigates the effectiveness of silver dressings to reduce bacteria in contaminated wounds when used with NPWT.
   Methods: Complex orthopedic wounds were created on the proximal left legs of anesthetized goats. The wounds were inoculated with either a strain of bioluminescent Pseudomonas aeruginosa or Staphylococcus aureus. These bacteria are genetically modified to emit photons, thereby allowing quantification of bacterial concentration with a photon-counting camera system. The wounds were debrided 6 hours after inoculation and were treated with silver impregnated gauze combined with NPWT. Repeat debridements were performed every 48 hours for 6 days. Imaging was performed pre- and postdebridement. These results were compared with standard NPWT controls that used dressings without silver.
   Results: There were fewer bacteria in the silver groups than the standard NPWT groups at 6 days. In the groups that were inoculated with P. aeruginosa, wounds in the silver group contained 21% +/- 5% of baseline bacterial load compared with 43% +/- 14% in the standard NPWT group. The addition of the silver dressings has a more pronounced effect on Staphylococcus. Wounds in the silver group contained 25% +/- 8% of baseline bacterial load compared with 115% +/- 19% in the standard NPWT group.
   Conclusions: The use of silver dressings with NPWT is a fairly common practice with limited literature to support its use in contaminated wounds. This study demonstrates that the addition of a silver dressing to NPWT effectively reduces bacteria in contaminated wounds and is more beneficial on the gram-positive bacteria. These data support the use of silver dressings in contaminated wounds, particularly ones contaminated by S. aureus.
C1 [Stinner, Daniel J.; Waterman, Scott M.; Masini, Brendan D.; Wenke, Joseph C.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
RP Wenke, JC (通讯作者)，USA, Inst Surg Res, 3400 Rawley E Chambers Ave, Ft Sam Houston, TX 78234 USA.
EM joseph.wenke@us.army.mil
RI Stinner, Daniel/KSM-9513-2024
OI Stinner, Daniel/0000-0002-8981-6262
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 18
TC 44
Z9 54
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0022-5282
J9 J TRAUMA
JI J. Trauma-Injury Infect. Crit. Care
PD JUL
PY 2011
VL 71
SU 1
BP S147
EP S150
DI 10.1097/TA.0b013e318221944a
PG 4
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC General & Internal Medicine; Surgery
GA 790RW
UT WOS:000292607900025
PM 21795872
DA 2026-07-24
ER

PT J
AU Atkins, BZ
   Wooten, MK
   Kistler, J
   Hurley, K
   Hughes, GC
   Wolfe, WG
AF Atkins, Broadus Zane
   Wooten, Mary Kay
   Kistler, Jean
   Hurley, Kista
   Hughes, G. Chad
   Wolfe, Walter G.
TI Does Negative Pressure Wound Therapy Have a Role in Preventing
   Poststernotomy Wound Complications?
SO SURGICAL INNOVATION
LA English
DT Article
DE subatmospheric pressure; wound healing; cardiac surgery; median
   sternotomy
ID VACUUM-ASSISTED CLOSURE; BYPASS GRAFT-SURGERY; LONG-TERM SURVIVAL;
   PERISTERNAL THORACIC WALL; SURGICAL-SITE INFECTIONS; RISK-FACTORS;
   BLOOD-FLOW; DEEP; MORTALITY; MEDIASTINITIS
AB Background: Sternal wound infection (SWI) remains a devastating complication after cardiac surgery, decreasing long-term and short-term survival. In treating documented SWI, negative pressure wound therapy (NPWT) reduces wound edema and time to definitive closure and improves peristernal blood flow after internal mammary artery (IMA) harvesting. The authors evaluated NPWT as a form of "well wound" therapy in patients at substantial risk for SWI based on existing risk stratification models. Methods: Records of 57 adult cardiac surgery patients (September 2006 to April 2008) were reviewed. After preoperative risk assessment, NPWT was instituted on the clean, closed sternotomy immediately after surgery and continued 4 days postoperatively. Adverse postoperative events, including SWI, need for readmission, and other complications, were documented. Results: Mean age was 60.4 +/- 10 years, and 89.5% were male; 77.2% were obese (mean body mass index 35.3 +/- 6.7), 54.4% were diabetic, and 29 (50.9%) were both obese and diabetic. Coronary artery bypass (CAB) with single IMA was performed in 50.9% of the patients followed in frequency by combined CAB/valve, non-CAB surgery, and CAB with bilateral IMA. Estimated risk for SWI was 6.1 +/- 4%. All patients tolerated NPWT to completion. Thirty-day and in-hospital mortality was 1.8% and unrelated to DSWI. No treatment of SWI was required. Conclusions: In this high-risk cohort, 3 postoperative SWI cases were anticipated but may have been mitigated by NPWT. This is an easily applied and well-tolerated therapy and may stimulate more effective wound healing. Among patients with increased SWI risk, strong consideration should be given to NPWT as a form of "well wound" therapy.
C1 [Atkins, Broadus Zane; Wooten, Mary Kay; Kistler, Jean; Hurley, Kista; Wolfe, Walter G.] Vet Affairs Med Ctr, Dept Surg, Minnepolis, MN USA.
   [Kistler, Jean; Hughes, G. Chad; Wolfe, Walter G.] Duke Univ, Med Ctr, Dept Surg, Durham, NC 27710 USA.
C3 US Department of Veterans Affairs; Veterans Health Administration (VHA);
   Duke University
RP Atkins, BZ (通讯作者)，Surg Serv, 112,508 Fulton St, Durham, NC 27705 USA.
EM Broadus.atkins@va.gov
RI Hughes, G. Chad/NOE-9906-2025
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   Sjögren J, 2005, ANN THORAC SURG, V80, P1270, DOI 10.1016/j.athoracsur.2005.04.010
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
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NR 41
TC 108
Z9 128
U1 0
U2 4
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1553-3506
EI 1553-3514
J9 SURG INNOV
JI Surg. Innov.
PD JUN
PY 2009
VL 16
IS 2
BP 140
EP 146
DI 10.1177/1553350609334821
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 479EQ
UT WOS:000268642900009
PM 19460818
DA 2026-07-24
ER

PT J
AU Collinge, C
   Reddix, R
AF Collinge, Cory
   Reddix, Robert
TI The Incidence of Wound Complications Related to Negative Pressure Wound
   Therapy Power Outage and Interruption of Treatment in Orthopaedic Trauma
   Patients
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article; Proceedings Paper
CT 51st Annual Meeting of the Society-of-Military-Orthopedic-Surgeons
   (SOMOS)
CY DEC 08, 2009
CL Honolulu, HI
SP Soc Mil Orthoped Surg
DE wound VAC; complications; wound; wound complications; negative pressure;
   infection
ID OPEN CELL FOAM; FRACTURES
AB Objective: Negative pressure wound therapy (NPWT) using the Vacuum Assisted Closure system is an invaluable tool for use on patients with complex limb and soft tissue problems. Recently, the manufacturer (Kinetic Concepts, Inc, San Antonio, TX) made significant modifications to the NPWT platform, including computer software, battery, alarming systems, electric cord and plug apparatus, and others. Since these modifications, we have seen several cases in which the NPWT device has powered off resulting in an unrecognized interruption of therapy. We sought to evaluate the conditions and clinical effects, if any, to orthopaedic trauma patients who experienced an interruption of NPWT therapy when the device powers off.
   Design: Retrospective study of consecutive patients.
   Setting: Two neighboring regional trauma centers.
   Patients: One hundred twenty-three consecutive orthopaedic trauma patients treated with NPWT by two orthopaedic trauma surgeons between May and November 2008.
   Main Outcome Measurements: Patient/injury, treatment, and perioperative clinical outcomes data (with emphasis on wound complications such as infection, graft loss, and unscheduled surgery) were collected from medical records and wound care databases.
   Results: Twelve patients (10%) had problems with the NPWT device powering off causing an unrecognized interruption of therapy. Eleven patients underwent early (less than 6 hours) wound debridement and reapplication of NPWT after detection, of which nine required unplanned surgery. Seven of the 12 patients recognized as having failed NPWT of this type ultimately experienced wound complications, including five deep infections and both patients being treated with an Integra graft (loss of graft).
   Conclusions: We have seen substantial problems in orthopaedic trauma patients treated with the NPWT, in which the device has powered off resulting in an unrecognized interruption of therapy. This has resulted in atypically unhealthy-appearing wounds, unplanned surgeries for debridement, and most importantly, an increased incidence of wound complications, including infection and graft loss (P < 0.05).
C1 [Collinge, Cory] Harris Methodist Ft Worth Hosp, Dept Orthoped Trauma, Ft Worth, TX USA.
   [Reddix, Robert] Univ N Texas, Orthopaed Training Program, Ft Worth Affiliated Hosp, Dept Orthoped Trauma,Dept Orthoped Surg,John Pete, Ft Worth, TX USA.
C3 University of North Texas System; University of North Texas Health
   Science Center
RP Collinge, C (通讯作者)，800 5th Ave,Suite 500, Ft Worth, TX 76104 USA.
EM ccollinge@msn.com
CR Dedmond BT, 2007, J ORTHOP TRAUMA, V21, P11, DOI 10.1097/BOT.0b013e31802cbc54
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   2007, EXTREMITY WAR INJURI
   2003, NATL PATIENT SAFETY
NR 20
TC 34
Z9 40
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0890-5339
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD FEB
PY 2011
VL 25
IS 2
BP 96
EP 100
DI 10.1097/BOT.0b013e3181de0134
PG 5
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Orthopedics; Sport Sciences
GA 708PA
UT WOS:000286375000011
PM 21245712
DA 2026-07-24
ER

PT J
AU Wedemeyer, J
   Lankisch, T
AF Wedemeyer, J.
   Lankisch, T.
TI Endoscopic vacuum-assisted closure
SO INTERNIST
LA German
DT Article
DE Anastomotic leak; Esophagus; Rectum; Vacuum-assisted closure; Drainage
ID ESOPHAGEAL ANASTOMOTIC LEAKS; PRESSURE WOUND THERAPY; ANTERIOR
   RESECTION; PLASTIC STENTS; RECTAL-CANCER; RISK-FACTORS; PANCREATITIS;
   NECROSECTOMY; PERFORATIONS; DRAINAGE
AB Anastomotic leakage in the upper and lower intestinal tract is associated with high morbidity and mortality. Within the last 10 years endoscopic treatment options have been accepted as sufficient treatment option of these surgical complications. Endoscopic vacuum assisted closure (E-VAC) is a new innovative endoscopic therapeutic option in this field. E-VAC transfers the positive effects of vacuum assisted closure (VAC) on infected cutaneous wounds to infected cavities that can only be reached endoscopically. A sponge connected to a drainage tube is endoscopically placed in the leakage and a continuous vacuum is applied. Sponge and vacuum allow removal of infected fluids and promote granulation of the leakage. This results in clean wound grounds and finally allows wound closure. Meanwhile the method was also successfully used in the treatment of necrotic pancreatitis.
C1 [Wedemeyer, J.] Klinikum Reg Hannover GmbH, Klinikum Robert Koch Gehrden, Schwerpunkt Gastroenterol & Hepatol, Med Klin 1, D-30989 Gehrden, Germany.
   [Lankisch, T.] Hannover Med Sch, Klin Gastroenterol Hepatol & Endokrinol, Hannover, Germany.
C3 Hannover Medical School
RP Wedemeyer, J (通讯作者)，Klinikum Reg Hannover GmbH, Klinikum Robert Koch Gehrden, Schwerpunkt Gastroenterol & Hepatol, Med Klin 1, Von Reden Str 1, D-30989 Gehrden, Germany.
EM jochen.wedemeyer@krh.eu
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NR 25
TC 1
Z9 1
U1 0
U2 4
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0020-9554
EI 1432-1289
J9 INTERNIST
JI Internist
PD MAR
PY 2013
VL 54
IS 3
BP 309
EP 313
DI 10.1007/s00108-012-3182-7
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 098TT
UT WOS:000315572700005
PM 23430199
DA 2026-07-24
ER

PT J
AU Masden, D
   Goldstein, J
   Endara, M
   Xu, K
   Steinberg, J
   Attinger, C
AF Masden, Derek
   Goldstein, Jesse
   Endara, Mathew
   Xu, Kyle
   Steinberg, John
   Attinger, Christopher
TI Negative Pressure Wound Therapy for At-Risk Surgical Closures in
   Patients With Multiple Comorbidities A Prospective Randomized
   Controlled Study
SO ANNALS OF SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; MESH GRAFTS; SKIN-GRAFTS;
   MULTICENTER; AMPUTATION; INCISIONS; IMPROVES
AB Purpose: The purpose of this study is to evaluate the effect of Negative Pressure Wound Therapy (NPWT) on closed surgical incisions. We performed a prospective randomized controlled clinical trial comparing NPWT to standard dry dressings on surgical incisions.
   Methods: Patients presenting to a high-volume wound center were randomized to receive either a V. A. C. (KCI, San Antonio, TX) or a standard dry dressing over their incision at the conclusion of surgery. These were primarily high-risk patients with multiple comorbidities. The 2 groups were compared, and all incisions were evaluated for infection and dehiscence postoperatively.
   Results: Eighty-one patients were included for analysis. Thirty-seven received dry dressings, and 44 received NPWT. Seventy-four of these underwent lower extremity wound closure. Average follow-up was 113 days. There were no differences in demographic, preoperative, and operative variables between groups; 6.8% of the NPWT group and 13.5% of the dry dressing group developed wound infection, but this was not statistically significant (P = 0.46). There was no difference in time to develop infection between the groups. There was no statistical difference in dehiscence between NPWT and dry dressing group (36.4% vs 29.7%; P = 0.54) or mean time to dehiscence between the 2 groups (P = 0.45). Overall, 35% of the dry dressing group and 40% of the NPWT group had a wound infection, dehiscence, or both. Of these, 9 in the NPWT group (21%) and 8 in the dry dressing group (22%) required reoperation.
   Conclusions: There is a significant rate of postoperative infection and dehiscence in patients with multiple comorbidities. There was no difference in the incidence of infection or dehiscence between the NPWT and dry dressing group. This study is registered with ClinicalTrials.gov. The unique registration number is NCT01366105.
C1 [Masden, Derek; Goldstein, Jesse; Endara, Mathew; Xu, Kyle; Steinberg, John; Attinger, Christopher] Georgetown Univ Hosp, Dept Plast Surg, Washington, DC 20007 USA.
C3 Georgetown University
RP Attinger, C (通讯作者)，Georgetown Univ Hosp, Dept Plast Surg, 3800 Reservoir Rd NW,Bless Bldg,1st Floor, Washington, DC 20007 USA.
EM cattinger@aol.com
RI Xu, Kyle/HCI-5630-2022
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NR 53
TC 88
Z9 104
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0003-4932
EI 1528-1140
J9 ANN SURG
JI Ann. Surg.
PD JUN
PY 2012
VL 255
IS 6
BP 1043
EP 1047
DI 10.1097/SLA.0b013e3182501bae
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 943DQ
UT WOS:000304101100016
PM 22549748
DA 2026-07-24
ER

PT J
AU Gamel, M
   Gael, M
   Bursztejn, AC
AF Gamel, M.
   Gael, M.
   Bursztejn, A. C.
TI Skin graft bolstered by negative pressure therapy in chronic wounds: A
   systematic review
SO JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
LA English
DT Review
DE chronic wounds; negative pressure wound therapy; skin graft
ID VACUUM-ASSISTED CLOSURE; CHRONIC LEG ULCERS; BED PREPARATION; TRIAL;
   INSTILLATION; MANAGEMENT; DEVICE
AB Background Chronic ulcers represent a significant burden for patients, often requiring advanced therapeutic interventions. Skin grafting is a critical treatment option, yet the risk of graft failure remains substantial. Negative pressure wound therapy (NPWT) has demonstrated efficacy in enhancing graft survival in acute wounds, but its effectiveness in chronic ulcers remains underexplored.Objective This systematic review aimed to evaluate the efficacy of NPWT in bolstering skin grafts for the treatment of chronic ulcers.Methods We conducted this systematic literature review using the scientific databases PUBMED, COCHRANE and EMBASE. Studies involving skin grafts supported by NPWT for chronic wounds were included, while those focussing on acute wounds, burns or post-surgical wounds were excluded. Data on patient demographics, wound characteristics, NPWT parameters and graft outcomes were extracted and analysed.Results A total of 21 articles, encompassing 186 patients, were included. The maximal graft uptake (>= 95%) was observed in 33% of patients, while 77% achieved a graft uptake of >= 90%. The mean graft take was 92% (89.7, 93.5, 95% confidence interval). Complete recovery was achieved in 79% of patients, with a mean recovery time of 73 days. Complete response without recurrence was noticed in 38% of the cases, with a mean time without recurrence of 197 days. Exploratory analyses indicated higher graft take rates in patients under 65 years, males, diabetics and those without arterial disease. Venous and neurotrophic ulcers also showed superior graft uptake.Conclusion NPWT appears to significantly enhance graft survival in chronic ulcers, with an excellent safety and tolerance profile. As there was no control group, historical controls of graft take without NPWT were used. Short-term NPWT application (less than 1 week) is recommended for optimal outcomes. These findings suggest that NPWT should be considered a preferred method for securing skin grafts in chronic ulcer management.
C1 [Gamel, M.; Gael, M.; Bursztejn, A. C.] Ctr Hosp Univ Nancy, Batiment P Canton, Dermatol, Vandoeuvre les Nancy, France.
C3 CHU de Nancy
RP Bursztejn, AC (通讯作者)，CHRU Nancy, Dermatol & Allergol Dept, Batiment Philippe Canton, Rue Morvan, F-54500 Vandoeuvre les Nancy, France.
EM ac.bursztejn@chru-nancy.fr
OI GAMEL, Mélina/0009-0006-8432-4505
CR Alavi A, 2016, J AM ACAD DERMATOL, V74, P627, DOI 10.1016/j.jaad.2014.10.048
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NR 37
TC 3
Z9 4
U1 3
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0926-9959
EI 1468-3083
J9 J EUR ACAD DERMATOL
JI J. Eur. Acad. Dermatol. Venereol.
PD FEB
PY 2026
VL 40
IS 2
BP 296
EP 304
DI 10.1111/jdv.20808
EA AUG 2025
PG 9
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA DC5FK
UT WOS:001557061600001
PM 40862371
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Shehata, MSA
   Bahbah, E
   El-Ayman, Y
   Abdelkarim, AH
   Abdalla, AR
   Morshedy, A
   Turkmani, K
   Seth, I
   Seth, N
AF Shehata, Mohamed S. A.
   Bahbah, Eshak
   El-Ayman, Yousef
   Abdelkarim, Ahmed H.
   Abdalla, Ahmed R.
   Morshedy, Ahmed
   Turkmani, Khaled
   Seth, Ishith
   Seth, Nimish
TI Effectiveness of Negative Pressure Wound Therapy in Patients With
   Challenging Wounds:A Systematic Review and Meta-analysis br
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Review
DE meta-analysis; negative pressure wound therapy; vacuum-assisted wound
   closure; wound healing
ID VACUUM-ASSISTED CLOSURE; MANAGEMENT; TRIAL; MULTICENTER; INFECTION;
   ULCERS; IMPACT; CARE
AB Introduction. Controversy exists regarding the use of NPWT for wound healing. Objective. This study assessed the effectiveness of NPWT compared with conventional treatment in the management of different wound types, including acute and chronic wounds. Materials and Methods. PubMed, Cochrane Central Register of Controlled Trials, Scopus, EMBASE, EBSCO, Ovid, and Web of Science were searched, from database inception up to October 2021, for relevant studies comparing NPWT with conventional treatment for wound healing. Primary outcomes included time to healing, wound healing rate, and duration of treatment. Secondary outcomes included adverse events, length of hospital stay, and 30-day mortality rate. Pooled analysis of the outcomes data is presented as SMD (95% CI) for continuous data and OR (95% CI) for dichotomous data. Results. Twenty-four studies (3064 patients) were included in the meta-analysis. NPWT was associated with shorter time to healing (SMD, -0.79; 95% CI, -1.22 to -0.37), shorter duration of treatment (SMD, -1.24; 95% CI, -1.92 to -0.56), and higher rate of wound healing (OR, 2.05; 95% CI, 1.49-2.83) compared with control. NPWT was also associated with a lower incidence of adverse events (OR, 0.42; 95% CI, 0.23-0.77) and a lower 30-day mortality rate (OR, 0.25; 95% CI, 0.12-0.56). There were no significant differences between NPWT and control regarding hospital stay (SMD, -0.52; 95% CI, -1.06 to 0.03). Conclusions. NPWT is seemingly associated with better wound healing outcomes compared with conventional therapy. However, the data should be interpreted with substantial caution given limitations such as high heterogeneity between studies and the small sample size of the included studies.
C1 [Shehata, Mohamed S. A.; El-Ayman, Yousef; Abdelkarim, Ahmed H.] Zagazig Univ, Fac Med, Zagazig, Egypt.
   [Shehata, Mohamed S. A.] Nasr City Insurance Hosp, Cairo, Egypt.
   [Bahbah, Eshak] Al Azhar Univ, Fac Med, Dumyat, Egypt.
   [Abdalla, Ahmed R.] Mansoura Univ, Fac Med, Mansoura, Egypt.
   [Morshedy, Ahmed] Kafrelsheikh Univ, Fac Med, Kafrelsheikh, Egypt.
   [Turkmani, Khaled] Damascus Univ, Fac Med, Damascus, Syria.
   [Seth, Ishith] Illawarra Shoalhaven Local Hlth Dist, Wollongong, Australia.
   [Seth, Nimish] Alfred Hosp, Dept Orthopaed, Melbourne, Australia.
   [Shehata, Mohamed S. A.] Nasr City Insurance Hosp, Cairo 44771, Egypt.
C3 Egyptian Knowledge Bank (EKB); Zagazig University; Egyptian Knowledge
   Bank (EKB); Al Azhar University; Egyptian Knowledge Bank (EKB); Mansoura
   University; Egyptian Knowledge Bank (EKB); Kafrelsheikh University;
   Damascus University; Illawarra Shoalhaven Local Health District; Florey
   Institute of Neuroscience & Mental Health; Howard Florey Institute
   Affiliates
RP Shehata, MSA (通讯作者)，Nasr City Insurance Hosp, Cairo 44771, Egypt.
EM mohamed.shehata6@outlook.com
RI ; El-Ayman, Yousef/ACI-3730-2022; Bahbah, Eshak/I-4504-2019; Abdelkarim,
   Ahmed/MAH-4449-2025; /S-9752-2017; Shehata, Mohamed/J-2933-2014
OI Shehata, Mohamed S.A/0000-0001-9580-4279; El-Ayman,
   Yousef/0000-0003-0711-4257; Bahbah, Eshak/0000-0002-6168-9134;
   Abdelkarim, Ahmed/0000-0002-6514-0077; 
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NR 53
TC 12
Z9 12
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD DEC
PY 2022
VL 34
IS 12
BP E126
EP E134
DI 10.25270/wnds/21061
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA A0QV4
UT WOS:000952271300004
PM 36645658
DA 2026-07-24
ER

PT J
AU Thomas, M
   Makey, IA
   Buchanan, MA
   Heckman, MG
   White, LJ
   Lechtenberg, BJ
   Wigle, D
   Shen, KR
   Blackmon, SH
AF Thomas, Mathew
   Makey, Ian A.
   Buchanan, Mauricia A.
   Heckman, Michael G.
   White, Launia J.
   Lechtenberg, Bettie J.
   Wigle, Dennis
   Shen, K. Robert
   Blackmon, Shanda H.
TI A Comparison of Negative Pressure and Conventional Therapy in Infected
   Open Chest Wounds
SO SURGICAL INFECTIONS
LA English
DT Article
DE bronchopleural fistula; chronic wound; empyema; negative pressure
   therapy; wound care
ID VACUUM-ASSISTED CLOSURE; ONSET ATRIAL-FIBRILLATION; OPEN WINDOW
   THORACOSTOMY; POSTPNEUMONECTOMY EMPYEMA; INTRATHORACIC APPLICATION;
   ACCELERATED TREATMENT; MANAGEMENT; RESECTION; DEVICE
AB Background: The role of negative pressure wound therapy (NPWT) in the management of open chest wounds is unclear. Our aim was to determine the safety and efficacy of NPWT compared with conventional therapy for open chest wounds.
   Methods: Ten patients with infected open chest wounds were included in a prospective trial of NPWT after surgical debridement. Their outcomes were compared with those of 11 control patients treated during the same period with surgical debridement and open chest packing only. The control group data were obtained by retrospective review of medical records.
   Results: The median duration of NPWT was eight days (range 2-29 days), with closure in eight patients (80%). Two patients having NPWT had unveiling of occult pleural fistulas leading to early discontinuation. The patients having NPWT had a shorter median time to closure (7 versus 18 days; p = 0.071) and shorter initial (median 6 versus 20 days; p = 0.026) and total (median 6 versus 25 days; p = 0.024) hospital length of stay. Control patients had higher rates of new-onset atrial fibrillation (46% versus 0; p = 0.035) and septic shock (64% versus 10%; p = 0.024). The chest was either closed or healing at the time of the last visit in 100% of the NPWT patients versus 73% of control patients (p = 0.28). The 1-year survival estimates were 90% for the NPWT patients and 80% for the control patients (p = 0.69).
   Conclusion: Negative pressure wound therapy is feasible and safe for open infected chest wounds in selected patients compared with open packing alone and may reduce hospital stay duration and major complication rates.
C1 [Thomas, Mathew; Makey, Ian A.; Buchanan, Mauricia A.] Mayo Clin, Dept Cardiothorac Surg, Jacksonville, FL 32224 USA.
   [Heckman, Michael G.; White, Launia J.] Mayo Clin, Dept Biomed Stat & Informat, Jacksonville, FL 32224 USA.
   [Lechtenberg, Bettie J.; Wigle, Dennis; Shen, K. Robert; Blackmon, Shanda H.] Mayo Clin, Div Thorac Surg, Rochester, MN USA.
C3 Mayo Clinic; Mayo Clinic; Mayo Clinic
RP Thomas, M (通讯作者)，Mayo Clin, Dept Cardiothorac Surg, Jacksonville, FL 32224 USA.
EM Thomas.mathew@mayo.edu
OI Thomas, Mathew/0000-0003-4609-0833
FU Thoracic Surgery Foundation through Acelity, Inc.
FX This project was funded by a peer-reviewed grant from the Thoracic
   Surgery Foundation through Acelity, Inc.
CR Al-Mufarrej F, 2010, SURG TODAY, V40, P711, DOI 10.1007/s00595-008-4096-9
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NR 25
TC 2
Z9 2
U1 0
U2 0
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD NOV 1
PY 2021
VL 22
IS 9
BP 955
EP 961
DI 10.1089/sur.2020.397
EA MAY 2021
PG 7
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA XB7KP
UT WOS:000655228200001
PM 34042543
DA 2026-07-24
ER

PT J
AU Ludwig-Slomczynska, AH
   Borys, S
   Seweryn, MT
   Hohendorff, J
   Kapusta, P
   Kiec-Wilk, B
   Pitera, E
   Wolkow, PP
   Malecki, MT
AF Ludwig-Slomczynska, A. H.
   Borys, S.
   Seweryn, M. T.
   Hohendorff, J.
   Kapusta, P.
   Kiec-Wilk, B.
   Pitera, E.
   Wolkow, P. P.
   Malecki, M. T.
TI DNA methylation analysis of negative pressure therapy effect in diabetic
   foot ulcers
SO ENDOCRINE CONNECTIONS
LA English
DT Article
DE diabetic foot syndrome; diabetic foot ulceration; DNA methylation;
   negative-pressure wound therapy; type 2 diabetes
ID VACUUM-ASSISTED CLOSURE; ALTERNATIVE ACTIVATION; CHRONIC INFLAMMATION;
   CLASSICAL PATHWAY; GENE-EXPRESSION; ELEVATED LEVELS; COMPLEMENT; GROWTH;
   INTERVENTIONS; EPIDEMIOLOGY
AB Objective: Negative pressure wound therapy (NPWT) has been used to treat diabetic foot ulcerations (DFUs). Its action on the molecular level, however, is only partially understood. Some earlier data suggested NPWT may be mediated through modification of local gene expression. As methylation is a key epigenetic regulatory mechanism of gene expression, we assessed the effect of NPWT on its profile in patients with type 2 diabetes (T2DM) and neuropathic non-infected DFUs.
   Methods: Of 36 included patients, 23 were assigned to NPWT and 13 to standard therapy. Due to ethical concerns, the assignment was non-randomized and based on wound characteristics. Tissue samples were obtained before and 8 +/- 1 days after therapy initiation. DNA methylation patterns were checked by Illumina Methylation EPIC kit.
   Results: In terms of clinical characteristics, the groups presented typical features of T2DM; however, the NPWT group had significantly greater wound area: 16.8 cm2 vs 1.4 cm(2) (P = 0.0003). Initially only one region at chromosome 5 was differentially methylated. After treatment, 57 differentially methylated genes were found, mainly located on chromosomes 6 (chr6p21) and 20 (chr20p13); they were associated with DNA repair and autocrine signaling via retinoic acid receptor. We performed differential analyses pre treatment and post treatment. The analysis revealed 426 differentially methylated regions in the NPWT group, but none in the control group. The enrichment analysis showed 11 processes significantly associated with NPWT, of which 4 were linked with complement system activation. All but one were hypermethylated after NPWT.
   Conclusion: The NPWT effect on DFUs may be mediated through epigenetic changes resulting in the inhibition of complement system activation.
C1 [Ludwig-Slomczynska, A. H.; Seweryn, M. T.; Kapusta, P.; Pitera, E.; Wolkow, P. P.] Jagiellonian Univ, Ctr Med Genom OMICRON, Med Coll, Krakow, Poland.
   [Borys, S.; Hohendorff, J.; Kiec-Wilk, B.; Malecki, M. T.] Jagiellonian Univ, Dept Metab Dis, Med Coll, Krakow, Poland.
   [Borys, S.; Hohendorff, J.; Kiec-Wilk, B.; Malecki, M. T.] Univ Hosp, Krakow, Poland.
C3 Jagiellonian University; Collegium Medicum Jagiellonian University;
   Jagiellonian University; Collegium Medicum Jagiellonian University;
   Jagiellonian University; Collegium Medicum Jagiellonian University
RP Wolkow, PP (通讯作者)，Jagiellonian Univ, Ctr Med Genom OMICRON, Med Coll, Krakow, Poland.; Malecki, MT (通讯作者)，Jagiellonian Univ, Dept Metab Dis, Med Coll, Krakow, Poland.; Malecki, MT (通讯作者)，Univ Hosp, Krakow, Poland.
EM pawel.wolkow@uj.edu.pl; maciej.malecki@uj.edu.pl
RI Seweryn, Michal/OEO-9216-2025; Pitera, Ewelina/G-6432-2019; Hohendorff,
   Jerzy/U-1857-2018; Wolkow, Pawel/AAI-4222-2021
OI Seweryn, Michal/0000-0002-9090-3435; Ludwig-Słomczyńska, Agnieszka
   H/0000-0002-0548-4767; Pitera, Ewelina/0000-0001-6208-5976; Hohendorff,
   Jerzy/0000-0003-1153-8669; Kapusta, Przemysław/0000-0003-4467-1175;
   Wolkow, Pawel/0000-0002-9322-5545
FU National Science Centre in Poland [2013/11/B/NZ5/03298]; European Union
   [FP7-REGPOT-2011-1, 286038]
FX The study was funded by the National Science Centre in Poland through
   the Opus Grant 'Assessment of molecular mechanisms of negative pressure
   wound therapy in the treatment of neuropathic ulceration in diabetic
   foot syndrome' to M T M (Nr 2013/11/B/NZ5/03298). The Omicron laboratory
   was funded by the European Union (7th Framework Programme, Call number
   FP7-REGPOT-2011-1, Grant number 286038).
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NR 45
TC 15
Z9 18
U1 0
U2 6
PU BIOSCIENTIFICA LTD
PI BRISTOL
PA STARLING HOUSE, 1600 BRISTOL PARKWAY N, BRISTOL, ENGLAND
SN 2049-3614
J9 ENDOCR CONNECT
JI Endocr. Connect.
PD NOV
PY 2019
VL 8
IS 11
BP 1474
EP 1482
DI 10.1530/EC-19-0373
PG 9
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA JS3XM
UT WOS:000500241600006
PM 31634866
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kepa, K
   Krzych, L
   Waclawczyk, T
   Krejca, M
AF Kepa, Krzysztof
   Krzych, Lukasz
   Waclawczyk, Tomasz
   Krejca, Michal
TI The use of negative pressure wound therapy in the treatment of wound
   infections - a single-center 12-month experience
SO KARDIOCHIRURGIA I TORAKOCHIRURGIA POLSKA-POLISH JOURNAL OF THORACIC AND
   CARDIOVASCULAR SURGERY
LA English
DT Article
DE cardiac surgery; infection; treatment; NPWT; VAC
ID VACUUM-ASSISTED CLOSURE; SURGICAL SITE INFECTION; RISK; MEDIASTINITIS
AB Background: The prevalence of surgical site infections (SSI) in cardiac surgery is about 0.5-10%, according to different sources, and leads to a prolonged hospital stay and higher mortality.
   The aim of the study was to describe the clinical outcomes of our 12-month experience using negative pressure wound therapy (NPWT).
   Material and methods: We performed a retrospective analysis of 32 patients undergoing NPWT between October 1, 2011 and September 30, 2012 (i.e. 2.7% of all patients who underwent surgical treatment in this period). Patient characteristics, risk factors, and procedure-related variables were analyzed and compared in two groups: group 1 included patients with infection of skin and subcutaneous tissue (1.2%), while group 2 consisted of patients with mediastinitis (1.6%).
   Results: Mediastinitis was three times more frequent among women (p = 0.09) and diabetics (p = 0.08), and four times more frequent in patients with chronic obstructive pulmonary disease (p = 0.2). The most frequently performed procedure was coronary artery bypass grafting (87.5%). Methicillin-resistant Staphylococcus epidermidis (26.2%) and Pseudomonas aeruginosa (21%) were the pathogens that were most frequently isolated from the infected wounds. The mean time of hospitalization was 64 +/- 35 days, which was similar in the two studied groups. In-hospital mortality in the mediastinitis group was 16.7%; no deaths were related to the use of NPWT therapy.
   Results: Our findings indicate that NPWT is a viable option for SSI treatment. Moreover, the use of NPWT may lower patient mortality, as well as reduce the length and costs of hospitalization. In order to achieve this, however, it is necessary to diagnose the infection early and to implement adequate treatment.
C1 [Kepa, Krzysztof; Krzych, Lukasz; Waclawczyk, Tomasz; Krejca, Michal] Gornoslaskie Ctr Med Katowicach, Oddzial Kardiochirurg, Katowicach, Poland.
RP Kepa, K (通讯作者)，Slaska 18-1, PL-40741 Katowice, Poland.
EM kepa.krzysiek@gmail.com
OI Wacławczyk, Tomasz/0000-0001-6504-2779; Krzych,
   Lukasz/0000-0002-5252-8398
CR Abu-Omar Y, 2003, ANN THORAC SURG, V76, P974, DOI 10.1016/S0003-4975(03)00180-2
   Berg TC, 2011, EUR J CARDIO-THORAC, V40, P1291, DOI 10.1016/j.ejcts.2011.02.038
   Berríos-Torres SI, 2012, INFECT CONT HOSP EP, V33, P463, DOI 10.1086/665313
   Darouiche R, 2012, PACE, V35, P1348, DOI 10.1111/j.1540-8159.2012.03506.x
   Eklund AM, 2006, ANN THORAC SURG, V82, P1784, DOI 10.1016/j.athoracsur.2006.05.097
   Faraday N, 2013, ANN SURG, V257, P150, DOI 10.1097/SLA.0b013e3182588abf
   Gummert JF, 2002, THORAC CARDIOV SURG, V50, P87, DOI 10.1055/s-2002-26691
   Mokhtari A, 2008, SCAND CARDIOVASC J, V42, P85, DOI 10.1080/14017430701744469
   Petzina R, 2010, EUR J CARDIO-THORAC, V38, P110, DOI 10.1016/j.ejcts.2010.01.028
   Raja Shahzad G, 2007, Interact Cardiovasc Thorac Surg, V6, P523, DOI 10.1510/icvts.2007.157370
   Simek M, 2012, J CARDIOVASC SURG, V53, P113
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   Tadros MA, 2013, AM J INFECT CONTROL, V41, P509, DOI 10.1016/j.ajic.2012.07.016
   Vos RJ, 2012, EUR J CARDIO-THORAC, V42, pE53, DOI 10.1093/ejcts/ezs404
NR 14
TC 1
Z9 1
U1 0
U2 4
PU TERMEDIA PUBLISHING HOUSE LTD
PI POZNAN
PA KLEEBERGA ST 2, POZNAN, 61-615, POLAND
SN 1731-5530
EI 1897-4252
J9 KARDIOCHIR TORAKOCHI
JI Kardiochirurgia Torakochirurg. Pol.
PD SEP
PY 2013
VL 10
IS 3
BP 204
EP 210
DI 10.5114/kitp.2013.38093
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 239EB
UT WOS:000326004300003
OA gold
DA 2026-07-24
ER

PT J
AU Listewnik, MJ
   Sielicki, P
   Mokrzycki, K
   Biskupski, A
   Brykczynski, M
AF Listewnik, Mariusz J.
   Sielicki, Piotr
   Mokrzycki, Krzysztof
   Biskupski, Andrzej
   Brykczynski, Miroslaw
TI The Use of Vacuum-Assisted Closure in Purulent Complications and
   Difficult-To-Heal Wounds in Cardiac Surgery
SO ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
LA English
DT Article
DE cardiac surgery; vacuum assisted therapy; wound infection
ID RISK-FACTORS; POSTOPERATIVE MEDIASTINITIS; INFECTIONS; THERAPY; SITE
AB Background. Sternal wound infections are a serious and potentially fatal complication of cardiac surgery.
   Objectives. The aim of the study was to analyze the results of using the vacuum-assisted closure (VAC) system over a 4-year period.
   Material and Methods. Quantitative VAC performance data from a retrospective review of a consecutive cohort of 47 patients treated with VAC for post-cardiac surgery wound complications were collected and statistically analyzed. In the study group 35 patients developed infections of the post-operative chest wound. In 12 other patients wound dehiscence was observed, but repeated cultures did not reveal the presence of any bacteria.
   Results. The statistical analysis identified the following as significant risk factors: age, female sex, being overweight, a high total logistic EuroScore, the use of both internal thoracic arteries for bypass grafting, and diabetes. In the wound negative culture group the total length of hospital stay was significantly shorter than in the wound positive culture group. Mortality in this group was 0.0% vs. 5.7% in the wound positive culture group. In the study material, Gram-negative bacteria were responsible for 77% of the post-operative wound infections, with only 14% Gram-positive wound cultures. No complications were related to VAC use.
   Conclusions. The use of negative-pressure wound therapy with other concomitant surgical procedures is a good method of treating infected wounds as well as non-contaminated dehiscence of the wound and sternum. Considering that most of the infections within the authors' department are caused by Gram-negative bacteria, it would be beneficial to consider modifying the model of preventive antibiotic treatment to cover the Gram-negative spectrum in addition to the Gram-positive bacteria currently targeted.
C1 [Listewnik, Mariusz J.; Sielicki, Piotr; Mokrzycki, Krzysztof; Biskupski, Andrzej; Brykczynski, Miroslaw] Pomeranian Med Univ, Dept Cardiac Surg, PL-70111 Szczecin, Poland.
C3 Pomeranian Medical University
RP Listewnik, MJ (通讯作者)，Pomeranian Med Univ, Dept Cardiac Surg, Powstancow Wielkopolskich 72, PL-70111 Szczecin, Poland.
EM sindbaad@poczta.onet.pl
RI Biskupski, Andrzej/J-2941-2014
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NR 15
TC 11
Z9 14
U1 1
U2 7
PU WROCLAW MEDICAL UNIV
PI WROCLAW
PA UL K MARCINKOWSKIEGO 2-6, WROCLAW, 50-368, POLAND
SN 1899-5276
EI 2451-2680
J9 ADV CLIN EXP MED
JI Adv. Clin. Exp. Med.
PD MAY-JUN
PY 2015
VL 24
IS 4
BP 643
EP 650
DI 10.17219/acem/28111
PG 8
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA CQ0LL
UT WOS:000360287300012
PM 26469109
OA gold
DA 2026-07-24
ER

PT J
AU Apelqvist, J
   Armstrong, DG
   Lavery, LA
   Boulton, AJM
AF Apelqvist, Jan
   Armstrong, David G.
   Lavery, Lawrence A.
   Boulton, Andrew J. M.
TI Resource utilization and economic costs of care based on a randomized
   trial of vacuum-assisted closure therapy in the treatment of diabetic
   foot wounds
SO AMERICAN JOURNAL OF SURGERY
LA English
DT Article
DE amputation; wound; ulcer; infection; resource utilization; diabetes
ID ULCERS; AMPUTATION; MELLITUS
AB BACKGROUND: To evaluate resource utilization and direct economic costs of care for patients treated with negative-pressure wound therapy (NPWT), using the Vacuum-Assisted Closure (V.A.C.) system, compared to standard moist wound therapy (MWT).
   METHODS: A total of 162 diabetic patients with post-amputation wounds (up to the trans-metatarsal level) entered a 16-week, randomized clinical trial. Patients randomized to V.A.C. (n = 77) received therapy with dressing changes every 48 hours. Control patients (n = 85) received standard MWT. Resource utilization, procedures, and direct costs were calculated and analyzed in this post hoc retrospective study.
   RESULTS: There was no difference between groups for in-patient hospital stay (number of admissions or length of stay). More surgical procedures (including debridement) were required in the MWT group (120 vs 43 NPWT, P < .001). The average number of dressing changes performed per patient was 118.0 (range 12-226) for MWT versus 41 (6-140) for NPWT (P = .0001). The MWT group had 11 (range 0-106) outpatient treatment visits during the study versus 4 (range 0-47) in the NPWT group (P < .05). The average direct cost per patient treated for 8 weeks or longer (independent of clinical outcome) was $27,270 and $36,096 in the NPWT and MWT groups, respectively. The average total cost to achieve healing was $25,954 for patients treated with NPWT (n = 43) compared with $38,806 for the MWT group (n = 33).
   CONCLUSION: Treatment of diabetic patients with post amputation wounds using NPWT resulted in lower resource utilization and a greater proportion of patients obtaining wound healing at a lower overall cost of care when compared to MWT. (C) 2008 Elsevier Inc. All rights reserved.
C1 [Armstrong, David G.] Rosalind Franklin Univ Med & Sci, Scholls Ctr Lower Extrem Ambulatory Res, Chicago, IL 60064 USA.
   [Apelqvist, Jan] Lund Univ, Div Clin Sci, Lund, Sweden.
   [Lavery, Lawrence A.] Texas A&M Univ, Dept Surg, Scott & White Hosp, Hlth Sci Ctr,Coll Med, Temple, TX USA.
   [Boulton, Andrew J. M.] Univ Miami, Miami, FL USA.
   [Boulton, Andrew J. M.] Manchester Royal Infirm, Univ Dept Med, Manchester M13 9WL, Lancs, England.
   [Apelqvist, Jan] Malmo Univ Hosp, Dept Endocrinol, Malmo, Sweden.
C3 Chicago Medical School; Rosalind Franklin University of Medicine &
   Science; Lund University; Texas A&M University System; Texas A&M
   University College Station; Texas A&M Health Science Center; University
   of Miami; University of Manchester; Lund University; Skane University
   Hospital
RP Armstrong, DG (通讯作者)，Rosalind Franklin Univ Med & Sci, Scholls Ctr Lower Extrem Ambulatory Res, 3333 Green Bay Rd, Chicago, IL 60064 USA.
EM david.armstrong@rosalindfranklin.edu
OI Lavery, Lawrence/0000-0002-7920-9952
CR Allenet B, 1999, DIABETOLOGIA, V42, pA308
   [Anonymous], 2004, WOUNDS, p3S
   Apelqvist J, 1998, Clin Podiatr Med Surg, V15, P21
   APELQVIST J, 1994, J INTERN MED, V235, P463, DOI 10.1111/j.1365-2796.1994.tb01104.x
   Armstrong David G, 2002, Ostomy Wound Manage, V48, P64
   Armstrong DG, 1998, DIABETES CARE, V21, P855, DOI 10.2337/diacare.21.5.855
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Boulton AJM, 2005, LANCET, V366, P1719, DOI 10.1016/S0140-6736(05)67698-2
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NR 24
TC 125
Z9 152
U1 0
U2 24
PU EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
PI BRIDGEWATER
PA 685 ROUTE 202-206 STE 3, BRIDGEWATER, NJ 08807 USA
SN 0002-9610
EI 1879-1883
J9 AM J SURG
JI Am. J. Surg.
PD JUN
PY 2008
VL 195
IS 6
BP 782
EP 788
DI 10.1016/j.amjsurg.2007.06.023
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 311FI
UT WOS:000256585700010
PM 18355797
DA 2026-07-24
ER

PT J
AU Chen, SF
   Chang, CC
AF Chen, Shiuan-Fu
   Chang, Chang-Cheng
TI Case Report: Negative pressure wound therapy with instillation and dwell
   time as adjuvant therapy for limb salvage in a complicated necrotizing
   fasciitis on ischemic diabetic foot
SO FRONTIERS IN SURGERY
LA English
DT Article
DE dermal substitute; diabetic foot ulcer; limb salvage; multidisciplinary
   management; multimodal therapy; necrotizing fasciitis; negative-pressure
   wound therapy with instillation and dwell time; negative-pressure wound
   therapy
ID DERMAL MATRIX; MANAGEMENT; DETERMINANTS; MORTALITY; ULCERS; SKIN
AB Background Necrotizing fasciitis superimposed on ischemic diabetic foot ulcers represents a complex and limb-threatening condition, especially in patients with multiple comorbidities such as end-stage renal disease, peripheral arterial occlusive disease, and poorly controlled diabetes mellitus. Optimal wound management strategies that minimize surgical burden while enhancing infection control and tissue regeneration are essential. This case highlights the use of multimodal adjuvant therapies and multidisciplinary management for limb salvage in a high-risk patient.Case presentation A 60-year-old woman with a Wagner grade 4 ischemic diabetic foot ulcer complicated by deep invasive necrotizing fasciitis underwent urgent extensive debridement, fasciotomy, and sequestrectomy, resulting in a large soft tissue defect with substantial bone and tendon exposure.Management A staged wound management approach was adopted, beginning with negative pressure wound therapy with instillation and dwell time using normal saline to promote bioburden reduction and granulation tissue formation. This was followed by the application of a dermal substitute combined with conventional negative pressure wound therapy to support dermal regeneration. Throughout the treatment course, multidisciplinary care was provided to optimize the management of systemic comorbidities.Outcome After four cycles of negative pressure wound therapy with instillation and dwell time, more than 70 percent of the wound bed, including previously exposed bone and tendon areas, was covered with healthy granulation tissue. Over the following three months, further tissue regeneration was achieved with the dermal substitute and negative pressure wound therapy. No additional surgical debridement was required, and limb preservation was successfully maintained without progression to systemic sepsis. Functionally, the patient ambulated with mobility assistance and reported minimal pain with good treatment acceptability. The patient subsequently died at month 5 from cardiovascular disease unrelated to the wound; wound stability through month 5 was recorded only in treating-team documentation.Conclusion This case demonstrates that a carefully staged multimodal adjuvant therapy protocol, incorporating negative pressure wound therapy with instillation and dwell time, dermal substitute application with negative pressure wound therapy, and multidisciplinary management of comorbidities, can serve as an effective limb salvage strategy in high-risk patients with diabetic foot ulcer-associated necrotizing fasciitis and extensive soft tissue defects when conventional reconstructive options are not feasible. This multimodal protocol may inform practice in high-risk or resource-limited settings.
C1 [Chen, Shiuan-Fu] Changhua Christian Hosp, Dept Med Educ, Div Gen Practice, Changhua, Taiwan.
   [Chang, Chang-Cheng] China Med Univ, Coll Med, Sch Med, Taichung, Taiwan.
   [Chang, Chang-Cheng] China Med Univ, Dept Cosmeceut, Taichung, Taiwan.
   [Chang, Chang-Cheng] China Med Univ Hosp, Dept Surg, Div Plast & Reconstruct Surg, Taichung, Taiwan.
   [Chang, Chang-Cheng] China Med Univ Hosp, Aesthet Med Ctr, Taichung, Taiwan.
C3 Changhua Christian Hospital; China Medical University Taiwan; China
   Medical University Taiwan; China Medical University Taiwan; China
   Medical University Hospital - Taiwan; China Medical University Taiwan;
   China Medical University Hospital - Taiwan
RP Chang, CC (通讯作者)，China Med Univ, Coll Med, Sch Med, Taichung, Taiwan.; Chang, CC (通讯作者)，China Med Univ, Dept Cosmeceut, Taichung, Taiwan.; Chang, CC (通讯作者)，China Med Univ Hosp, Dept Surg, Div Plast & Reconstruct Surg, Taichung, Taiwan.; Chang, CC (通讯作者)，China Med Univ Hosp, Aesthet Med Ctr, Taichung, Taiwan.
EM changcc1975@gmail.com
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NR 30
TC 0
Z9 0
U1 0
U2 0
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-875X
J9 FRONT SURG
JI Front. Surg.
PD FEB 5
PY 2026
VL 13
AR 1687275
DI 10.3389/fsurg.2026.1687275
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DX5AG
UT WOS:001694409300001
PM 41727898
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Izadpanah, K
   Hansen, S
   Six-Merker, J
   Helwig, P
   Südkamp, NP
   Schmal, H
AF Izadpanah, Kaywan
   Hansen, Stephanie
   Six-Merker, Julia
   Helwig, Peter
   Suedkamp, Norbert P.
   Schmal, Hagen
TI Factors influencing treatment success of negative pressure wound therapy
   in patients with postoperative infections after Osteosynthetic fracture
   fixation
SO BMC MUSCULOSKELETAL DISORDERS
LA English
DT Article
DE Infection; Osteosynthesis; Npwt; Vac; Clinical trial; Logistic
   regression models
ID VACUUM-ASSISTED CLOSURE; SOFT-TISSUE RECONSTRUCTION; MANAGEMENT;
   MULTICENTER
AB Background: Negative Pressure Wound Therapy (NPWT) is being increasingly used to treat postoperative infections after osteosynthetic fracture fixation. The aim of the present study was to analyze the influence of epidemiological and microbiological parameters on outcome.
   Methods: Infections following operative fracture fixation were registered in a comprehensive Critical Incidence Reporting System and subsequently analyzed retrospectively for characteristics of patients including comorbidity, bacteria, and clinical factors. The influence of the investigated parameters was analyzed using logistic regression models based on data from 106 patients.
   Results: Staged wound lavage in combination with NPWT allowed implant preservation in 44% and led to successful healing in 73% of patients. Fermentation characteristics, load and behavior after gram staining revealed no statistically significant correlation with either healing or implant preservation. Infecting bacteria were successfully isolated in 87% of patients. 20% of all infections were caused by bacterial combinations. We observed a change in the infecting bacterial species under therapy in 23%. Age, gender, metabolic diseases or comorbidities did not influence the probability of implant preservation or healing. The delayed manifestation of infection (>4 weeks) correlated with a higher risk for implant loss (OR 5.1 [95% CI 1.41-17.92]) as did the presence of bacterial mixture (OR 5.0 [95% CI 1.41-17.92]) and open soft-tissue damage >= grade 3 (OR 10.2 [CI 1.88-55.28]). Wounds were less likely to heal in conjunction with high CRP blood levels (>20 mg/l) at the time of discharge (OR 3.6 [95% CI 1.31-10.08]) or following a change of the infecting bacterial species under therapy (OR 3.2 [95% CI, 1.13-8.99]).
   Conclusions: These results indicate that the delayed manifestation of infection, high CRP blood levels at discharge, and alterations in the infecting bacterial species under therapy raise the risk of NPWT failure.
C1 [Izadpanah, Kaywan; Hansen, Stephanie; Helwig, Peter; Suedkamp, Norbert P.; Schmal, Hagen] Univ Hosp Freiburg, Dept Orthoped & Trauma Surg, Freiburg, Germany.
   [Six-Merker, Julia] Helmholtz Zentrum Munchen, Munich, Germany.
   [Schmal, Hagen] Univ Southern Denmark, Dept Orthoped & Traumatol, Odense Univ Hosp, Sdr Blvd 29, DK-5000 Odense C, Denmark.
   [Schmal, Hagen] Univ Southern Denmark, Dept Clin Res, Sdr Blvd 29, DK-5000 Odense C, Denmark.
C3 University of Freiburg; Helmholtz Association; Helmholtz-Center Munich -
   German Research Center for Environmental Health; University of Southern
   Denmark; Odense University Hospital; University of Southern Denmark
RP Schmal, H (通讯作者)，Univ Hosp Freiburg, Dept Orthoped & Trauma Surg, Freiburg, Germany.; Schmal, H (通讯作者)，Univ Southern Denmark, Dept Orthoped & Traumatol, Odense Univ Hosp, Sdr Blvd 29, DK-5000 Odense C, Denmark.; Schmal, H (通讯作者)，Univ Southern Denmark, Dept Clin Res, Sdr Blvd 29, DK-5000 Odense C, Denmark.
EM hagen.schmal@freenet.de
RI Suedkamp, Norbert/AAF-2931-2019; Izadpanah, Kaywan/OGO-0168-2025;
   Schmal, Hagen/B-2684-2016
OI Schmal, Hagen/0000-0002-8801-2385
FU German Research Foundation (DFG); University of Freiburg in the funding
   program Open Access Publishing
FX The article processing charge was funded by the German Research
   Foundation (DFG) and the University of Freiburg in the funding program
   Open Access Publishing.
CR [Anonymous], 2001, COCHRANE DB SYST REV, DOI [DOI 10.001002/14651858.CD14000244.PUB14651852, DOI 10.1002/14651858]
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NR 26
TC 6
Z9 8
U1 0
U2 5
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2474
J9 BMC MUSCULOSKEL DIS
JI BMC Musculoskelet. Disord.
PD JUN 7
PY 2017
VL 18
AR 247
DI 10.1186/s12891-017-1607-0
PG 10
WC Orthopedics; Rheumatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Rheumatology
GA EW9NO
UT WOS:000402846700002
PM 28592300
OA Green Submitted, Green Published, gold
DA 2026-07-24
ER

PT J
AU Friedman, T
   Westreich, M
   Shalom, A
AF Friedman, T
   Westreich, M
   Shalom, A
TI Vacuum-assisted closure treatment complicated by anasarca
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE vacuum-assisted treatment; hypoalbuminemia; anasarca; compromised
   patient; rare complication
ID WOUND CONTROL
AB The vacuum-assisted closure system has proven to be effective and safe in the treatment of a variety of wound types. in this case report, we present a rare complication of anasarca due to hypoalbuminemia, which developed during vacuum-assisted closure treatment. The patient was known to suffer from clinically stable congestive heart failure and had not had previous hypoalbuminemia. We emphasize the need for careful monitoring of electrolytes and proteins in compromised patients that have marked wound drainage when they are treated with a negative-pressure apparatus.
C1 Assaf Harofeh Med Ctr, Dept Plast Surg, IL-70300 Zerifin, Israel.
   Tel Aviv Univ, Sackler Fac Med, Ramat Aviv, Israel.
C3 Tel Aviv University; Shamir Medical Center (Assaf Harofeh); Tel Aviv
   University; Sackler Faculty of Medicine
RP Friedman, T (通讯作者)，Assaf Harofeh Med Ctr, Dept Plast Surg, IL-70300 Zerifin, Israel.
EM mony@netvision.net.il
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   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
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NR 8
TC 9
Z9 10
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD OCT
PY 2005
VL 55
IS 4
BP 420
EP 421
DI 10.1097/01.sap.0000174361.52084.6e
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 970CM
UT WOS:000232282800018
PM 16186711
DA 2026-07-24
ER

PT J
AU Sziklavari, Z
   Ried, M
   Zeman, F
   Grosser, C
   Szöke, T
   Neu, R
   Schemm, R
   Hofmann, HS
AF Sziklavari, Zsolt
   Ried, Michael
   Zeman, Florian
   Grosser, Christian
   Szoke, Tamas
   Neu, Reiner
   Schemm, Rudolf
   Hofmann, Hans-Stefan
TI Short-term and long-term outcomes of intrathoracic vacuum therapy of
   empyema in debilitated patients
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
DE Negative pressure wound therapy; VAC; Vacuum-assisted closure;
   Intrapleural; Intrathoracic; Empyema
ID OPEN-WINDOW THORACOSTOMY; ASSISTED CLOSURE THERAPY; PLEURAL EMPYEMA;
   LUNG RESECTION; INSTILLATION
AB Background: This retrospective study analyzed the effectiveness of intrathoracic negative pressure therapy for debilitated patients with empyema and compared the short-term and long-term outcomes of three different intrapleural vacuum-assisted closure (VAC) techniques.
   Methods: We investigated 43 consecutive (pre) septic patients with poor general condition (Karnofsky index <= 50 %) and multimorbidity (>= 3 organ diseases) or immunosuppression, who had been treated for primary, postoperative, or recurrent pleural empyema with VAC in combination with open window thoracostomy (OWT-VAC) with minimally invasive technique (Mini-VAC), and instillation (Mini-VAC-Instill).
   Results: The overall duration of intrathoracic vacuum therapy was 14 days (5-48 days). Vacuum duration in the Mini-VAC and Mini-VAC-Instill groups (12.4 +/- 5.7 and 10.4 +/- 5.4 days) was significantly shorter (p = 0.001) than in the group treated with open window thoracostomy (OWT)-VAC (20.3 +/- 9.4 days). No major complication was related to intrathoracic VAC therapy. Chest wall closure rates were significantly higher in the Mini-VAC and Mini-VAC-Instill groups than in the OWT-VAC group (p = 0.034 and p = 0.026). Overall, the mean postoperative length of stay in hospital (LOS) was 21 days (median 18, 6-51 days). LOS was significantly shorter (p = 0.027) in the Mini-VAC-Instill group (15.1 +/- 4.8) than in the other two groups (23.8 +/- 12.3 and 22.7 +/- 1.5). Overall, the 30-day and 60-day mortality rates were 4.7 % (2/43) and 9.3 % (4/43), and none of the deaths was related to infection.
   Conclusions: For debilitated patients, immediate minimally invasive intrathoracic vacuum therapy is a safe and viable alternative to OWT. Mini-VAC-Instill may have the fastest clearance and healing rates of empyema.
C1 [Sziklavari, Zsolt; Grosser, Christian; Szoke, Tamas; Schemm, Rudolf; Hofmann, Hans-Stefan] Krankenhaus Barmherzige Bruder Regensburg, Dept Thorac Surg, Prufeningerstr 86, D-93049 Regensburg, Germany.
   [Ried, Michael; Neu, Reiner; Hofmann, Hans-Stefan] Univ Med Ctr Regensburg, Dept Thorac Surg, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany.
   [Zeman, Florian] Univ Med Ctr Regensburg, Ctr Clin Studies, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany.
C3 University of Regensburg; University of Regensburg
RP Sziklavari, Z (通讯作者)，Krankenhaus Barmherzige Bruder Regensburg, Dept Thorac Surg, Prufeningerstr 86, D-93049 Regensburg, Germany.
EM sziklavari_zsolt@yahoo.com
RI Ried, Michael/AAC-4518-2022; Zeman, Florian/GNH-3239-2022; Sziklavari,
   Zsolt/AGI-2440-2022
OI Ried, Michael/0000-0002-2365-4803; Zeman, Florian/0000-0002-8425-984X; 
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NR 14
TC 16
Z9 22
U1 0
U2 4
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD OCT 21
PY 2016
VL 11
AR 148
DI 10.1186/s13019-016-0543-7
PG 8
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA DZ8BQ
UT WOS:000386094000001
PM 27769303
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Hobeika, C
   Allard, MA
   Bucur, PO
   Naili, S
   Cunha, AS
   Cherqui, D
   Castaing, D
   Adam, R
   Vibert, E
AF Hobeika, Christian
   Allard, Marc-Antoine
   Bucur, Petru-Octav
   Naili, Salima
   Cunha, Antonio Sa
   Cherqui, Daniel
   Castaing, Denis
   Adam, Rene
   Vibert, Eric
TI Management of the Open Abdomen after Liver Transplantation
SO WORLD JOURNAL OF SURGERY
LA English
DT Article
ID ABDOMINAL-WALL RECONSTRUCTION; VACUUM-ASSISTED CLOSURE; PRESSURE WOUND
   THERAPY; FASCIAL CLOSURE; VENTRAL HERNIA; TRAUMA
AB The optimal management of the open abdomen (OA) after liver transplantation (LT) is unclear. The negative pressure wound therapy (NPWT) has been shown to be safe and can increase the chance for early fascial closure in trauma or septic patients. However, little data are available on the specific setting of LT. We aimed to report our experience of OA after LT, marked by the recent use of NPWT.
   All patients with postponed wall closure after LT, from 2002 to 2014, in a single institution were included and retrospectively analyzed. Our management of OA after LT has shifted from skin-only closure (SOC) followed by abdominal wall reconstruction at a distance to the use of NPWT with early fascial closure.
   Of the 1559 LTs performed during the study period, immediate abdominal wall closure at the end of transplantation could not be achieved in 46 (2.9%) patients. Of them, SOC was performed in 22 (47.8%) patients, whereas vacuum-assisted closure (VAC) therapy was used in 24 (52.1%) patients. The comprehensive complication indexes (CCI) were similar [CCI: 66 (0-100) in the SOC group vs. 56 (0-100) in the VAC group; p = 0.55]. No evisceration or fistula occurred in both groups. One (4.2%) postoperative bleeding case was reported in the VAC group. Early fascial closure was achieved within a median of 5.5 days (1-12) for the 24 patients (100%) of the VAC group. In four of them, a biological mesh was necessary. Only nine patients (52.9%) of the survivors in the SOC group underwent abdominal reconstruction.
   The NPWT in patients with OA after LT enables early fascial closure with limited morbidity provided a specific attention is given to the risk of bleeding. These results support the use of NPWT as the first option in OA patients after LT.
C1 [Hobeika, Christian; Allard, Marc-Antoine; Bucur, Petru-Octav; Naili, Salima; Cunha, Antonio Sa; Cherqui, Daniel; Castaing, Denis; Adam, Rene; Vibert, Eric] Hop Paul Brousse, Ctr Hepatobiliaire, 14 Av Paul Vaillant Couturier, F-94800 Villejuif, France.
   [Allard, Marc-Antoine; Bucur, Petru-Octav; Cunha, Antonio Sa; Cherqui, Daniel; Castaing, Denis; Adam, Rene; Vibert, Eric] Univ Paris Sud, Villejuif, France.
   [Allard, Marc-Antoine; Cunha, Antonio Sa; Adam, Rene] INSERM, Unite 935, Inst Natl Sante & Rech, Paris, France.
   [Bucur, Petru-Octav; Cherqui, Daniel; Castaing, Denis; Vibert, Eric] INSERM, Unite 785, Paris, France.
C3 Assistance Publique Hopitaux Paris (APHP); Hopital Universitaire
   Paul-Brousse - APHP; Universite Paris Saclay; Institut National de la
   Sante et de la Recherche Medicale (Inserm); Institut National de la
   Sante et de la Recherche Medicale (Inserm)
RP Allard, MA (通讯作者)，Hop Paul Brousse, Ctr Hepatobiliaire, 14 Av Paul Vaillant Couturier, F-94800 Villejuif, France.; Allard, MA (通讯作者)，Univ Paris Sud, Villejuif, France.; Allard, MA (通讯作者)，INSERM, Unite 935, Inst Natl Sante & Rech, Paris, France.
EM marcantoineallard@yahoo.fr
RI Hobeika, Christian/AAN-5865-2020; Cherqui, Daniel/T-6831-2018; VIBERT,
   Eric/T-7746-2018; Allaes, Marc Antoine/HTM-5009-2023; sa cunha,
   antonio/B-5781-2012
OI Hobeika, Christian/0000-0002-9592-2520; sa cunha,
   antonio/0000-0003-4015-5368
CR Assirati G, 2016, TRANSPL P, V48, P383, DOI 10.1016/j.transproceed.2015.12.037
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NR 22
TC 6
Z9 8
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD DEC
PY 2017
VL 41
IS 12
BP 3199
EP 3204
DI 10.1007/s00268-017-4125-1
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FM5RK
UT WOS:000415095500027
PM 28717912
DA 2026-07-24
ER

PT J
AU Jordan, CJ
   Kulendra, E
   Perry, KL
   Halfacree, ZJ
AF Jordan, C. J.
   Kulendra, E.
   Perry, K. L.
   Halfacree, Z. J.
TI Management of peristomal tissue necrosis following prepubic urethrostomy
   in a cat
SO VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY
LA English
DT Article
DE Prepubic urethrostomy; vacuum assisted closure; urogenital;
   reconstructive surgery; temporary urethral ligation
ID VACUUM-ASSISTED CLOSURE; WOUND CONTROL; SKIN; DOGS
AB This report describes the successful management of peristomal tissue necrosis following prepubic urethrostomy in a cat. The novel technique of temporary urethral ligation was used in combination with temporary tube cystostomy and vacuum assisted closure to allow for wound management prior to performing wound closure by utilization of a flank fold skin flap then definitive prepubic urethrostomy. Eleven month follow-up indicated excellent outcome with the cat having returned to normal behaviour apart from having adapted its posture to urinate.
C1 [Kulendra, E.; Perry, K. L.; Halfacree, Z. J.] Royal Vet Coll, Small Anim Med & Surg Grp, Hatfield, Herts, England.
C3 University of London; University of London Royal Veterinary College
RP Jordan, CJ (通讯作者)，Poles Lane, Winchester SO21 2LL, Hants, England.
EM chris@andersonmoores.com
RI Perry, Karen/AAY-7641-2020
OI Perry, Karen/0000-0001-6456-1817; Halfacree, Zoe/0000-0001-6891-8828;
   Kulena, Elvin/0000-0002-2026-3065
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NR 19
TC 6
Z9 7
U1 0
U2 5
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0932-0814
EI 2567-6911
J9 VET COMP ORTHOPAED
JI Vet. Comp. Orthop. Traumatol.
PY 2012
VL 25
IS 5
BP 433
EP 437
DI 10.3415/VCOT-11-11-0168
PG 5
WC Veterinary Sciences; Zoology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences; Zoology
GA 012QU
UT WOS:000309252400014
PM 22829103
OA Bronze
DA 2026-07-24
ER

PT J
AU Wilkes, RP
   McNulty, AK
   Feeley, TD
   Schmidt, MA
   Kieswetter, K
AF Wilkes, Robert P.
   McNulty, Amy K.
   Feeley, Teri D.
   Schmidt, Marisa A.
   Kieswetter, Kris
TI Bioreactor for application of subatmospheric pressure to
   three-dimensional cell culture
SO TISSUE ENGINEERING
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; COLLAGEN-MATRIX; IN-VITRO; FIBROBLASTS; WOUNDS;
   MECHANOTRANSDUCTION; DIFFERENTIATION; PROLIFERATION; STIMULATION;
   FOUNDATION
AB Vacuum-assisted closure (VAC) negative pressure wound therapy (NPWT) is a highly successful and widely used treatment modality for wound healing, although no apparatus exists to monitor the effects of subatmospheric pressure application in vitro. Such an apparatus is desirable to better understand the biological effects of this therapy and potentially improve upon them. This article describes the development and validation of a novel bioreactor that permits such study. Tissue analogues consisting of 3-dimensional fibroblast-containing fibrin clots were cultured in off-the-shelf disposable cell culture inserts and multiwell plates that were integrated into the bioreactor module. Negative pressure dressings, commercialized for wound therapy, were placed on top of the culture, and subatmospheric pressure was applied to the dressing. Cultures were perfused with media at controlled physiologic wound exudate flow rates. The design of this bioreactor permits observation of the culture using an inverted microscope in brightfield and fluorescence modes and sustained incubation of the system in a 5% carbon dioxide atmosphere. This closed-system mimics the wound micro-environment under VAC NPWT. Matrix compression occurs as the subatmospheric pressure draws the dressing material down. At the contact zone, surface undulations were clearly evident on the fibroblast-containing tissue analogues at 24 h and appeared to correspond to the dressing microstructure. The bioreactor design, consisting of sterilizable machined plastics and disposable labware, can be easily scaled to multiple units. Validation experiments show that cell survival in this system is comparable with that seen in cells grown in static tissue culture. After application of VAC NPWT, cell morphology changed, with cells appearing thicker and with an organized actin cytoskeleton. The development and validation of this new culture system establishes a stable platform for in vitro investigations of subatmospheric pressure application to tissues.
C1 [Wilkes, Robert P.; McNulty, Amy K.; Feeley, Teri D.; Schmidt, Marisa A.; Kieswetter, Kris] Kinetic Concepts Inc, San Antonio, TX USA.
RP Wilkes, RP (通讯作者)，Kinetic Concepts Inc, San Antonio, TX USA.
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NR 27
TC 20
Z9 26
U1 0
U2 10
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 2152-4947
J9 TISSUE ENG
JI Tissue Eng.
PD DEC
PY 2007
VL 13
IS 12
BP 3003
EP 3010
DI 10.1089/ten.2007.0036
PG 8
WC Cell & Tissue Engineering
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology
GA 243HW
UT WOS:000251788400020
PM 17988192
DA 2026-07-24
ER

PT J
AU Tian, C
   Xu, KH
   Zhao, YN
   Li, YH
   Wu, KP
   Jiao, DC
   Han, XW
AF Tian, Chuan
   Xu, Kaihao
   Zhao, Yanan
   Li, Yahua
   Wu, Kunpeng
   Jiao, Dechao
   Han, Xinwei
TI Vacuum sealing drainage combined with naso-intestinal and gastric
   decompression tubes for the treatment of esophagogastrostomy neck
   fistula
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
DE Vacuum sealing drainage; Nutritional tube; Gastric decompression tube;
   Esophagogastrostomy; Fistula
ID ANASTOMOTIC LEAK; RISK-FACTORS; STENT; ESOPHAGECTOMY; VANCOMYCIN;
   STRICTURE
AB Objective To evaluate the clinical results of the vacuum sealing drainage (VSD) combined with a naso-intestinal nutritional tube (NIT) and a gastric decompression tube (GDT) for the treatment of esophagogastrostomy neck fistula (ENF). Methods From January 2018 to October 2020, twenty patients (13 men and 7 women, ages 46-72) with ENF secondary to esophagogastrostomy were treated with VSD combined with NIT and GDT. Technical and clinical success rates, the incidence of early/late complications, the time of fistula closure (TFC) and therapy-related indicators were analyzed. The Karnofsky score and Eastern Cooperative Oncology Group (ECOG) score were compared before and after triple treatment. Results Technical and clinical success rates were 100% and 85%, respectively. Early complications occurred in 5/20 (25%) patients, and late complications occurred in 8/20 (40%) patients. The median TFC was 18 days (range 10-23). All therapy-related indicators were normalized posttreatment. The Karnofsky score and ECOG score after treatment were significantly different compared with pretreatment scores (p < 0.001). Conclusion VSD combined with NIT and GDT is a safe and effective strategy for ENF, while severe strictures warrant further research.
C1 [Tian, Chuan; Xu, Kaihao; Zhao, Yanan; Li, Yahua; Wu, Kunpeng; Jiao, Dechao; Han, Xinwei] Zhengzhou Univ, Affiliated Hosp 1, Dept Intervent Radiol, 1 Jianshe East Rd, Zhengzhou 450052, Henan, Peoples R China.
C3 Zhengzhou University
RP Jiao, DC; Han, XW (通讯作者)，Zhengzhou Univ, Affiliated Hosp 1, Dept Intervent Radiol, 1 Jianshe East Rd, Zhengzhou 450052, Henan, Peoples R China.
EM jiaodechao007@126.com; fcchanxw@zzu.edu.cn
RI Wu, Kunpeng/AEB-7274-2022; Zhao, Yanan/KHY-2872-2024; han,
   wei/ABG-2691-2021; Dechao, Jiao/ABH-1680-2021
OI Wu, Kunpeng/0000-0001-6408-8927; 
FU Young and Middle-aged Health Science and Technology Innovation Talent
   Project of Henan Province in 2020 [yxkc2020037]; Youth Project of Henan
   Provincial Health Commission and Ministry Jointly Support [sb201902014]
FX This work was supported by the Young and Middle-aged Health Science and
   Technology Innovation Talent Project of Henan Province in 2020
   (yxkc2020037) and the Youth Project of Henan Provincial Health
   Commission and Ministry Jointly Support (sb201902014).
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NR 33
TC 6
Z9 6
U1 0
U2 6
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD JUN 13
PY 2022
VL 17
IS 1
AR 153
DI 10.1186/s13019-022-01883-x
PG 8
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 2C2DL
UT WOS:000810685000002
PM 35698141
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Chang, CC
   Tang, WR
   Huang, WL
   Chen, YY
   Yen, YT
   Tseng, YL
AF Chang, Chao-Chun
   Tang, Wen-Ruei
   Huang, Wei-Li
   Chen, Ying-Yuan
   Yen, Yi-Ting
   Tseng, Yau-Lin
TI Algorithmic Approach Using Negative Pressure Wound Therapy Improved
   Survival for Patients with Synchronous Hypopharyngeal and Esophageal
   Cancer Undergoing Pharyngolaryngoesophagectomy with Gastric Tube
   Reconstruction
SO ANNALS OF SURGICAL ONCOLOGY
LA English
DT Article
ID SQUAMOUS-CELL CARCINOMA; INTRAABDOMINAL ABSCESS; PHARYNGOCUTANEOUS
   FISTULA; PERCUTANEOUS DRAINAGE; PULL-UP; HEAD; NECK; MANAGEMENT; IMPACT;
   SURGERY
AB Background This study retrospectively analyzed the feasibility and surgical outcome of an algorithmic approach using negative pressure wound therapy for patients with synchronous hypopharyngeal and esophageal cancer undergoing pharyngolaryngoesophagectomy with gastric tube reconstruction. Methods Patients undergoing pharyngolaryngoesophagectomy and gastric tube reconstruction for hypopharyngeal cancer between 2011 and 2019 were candidates for this study. Data were collected on patient demographics, comorbidities, performance status, cancer stage, treatment, complication, and survival. Survival analysis was performed using the Kaplan-Meier method. The Cox proportional hazards model was used for prognostic factors. Results The study enrolled 43 patients. Anastomotic leakage was found in 21 of the patients with a conventional surgical drain (61.9%) and in 10 of the 22 patients with negative pressure wound therapy (45.5%) (p = 0.280). Nine patients in the conventional drain group (42.9%) and two patients in the negative pressure wound therapy group (9.1%) had leakage-associated complications (p = 0.011). The incidence of pulmonary complications was higher in the conventional surgical drain group (9 vs 2; p = 0.011). The number of complications requiring surgery was higher in the conventional drain group (7 vs 0; p = 0.004). The overall survival in the negative pressure wound therapy group was better (hazard ratio [HR], 0.33; 95% confidence interval [CI], 0.15-0.76; p = 0.009). Negative pressure wound therapy was independently associated with overall survival (HR, 0.31; 95% CI, 0.13-0.77; p = 0.011). Conclusions Negative pressure wound therapy with an algorithmic approach improved the overall survival for the patients undergoing gastric tube reconstruction after pharyngolaryngoesophagectomy for hypopharyngeal and esophageal cancer by preventing deadly complications secondary to anastomotic leakage
C1 [Chang, Chao-Chun; Tang, Wen-Ruei; Huang, Wei-Li; Chen, Ying-Yuan; Yen, Yi-Ting; Tseng, Yau-Lin] Natl Cheng Kung Univ Hosp, Dept Surg, Div Thorac Surg, Tainan, Taiwan.
   [Chang, Chao-Chun; Yen, Yi-Ting] Natl Cheng Kung Univ Hosp, Dept Surg, Div Trauma & Acute Care Surg, Tainan, Taiwan.
C3 National Cheng Kung University; National Cheng Kung University Hospital;
   National Cheng Kung University; National Cheng Kung University Hospital
RP Yen, YT (通讯作者)，Natl Cheng Kung Univ Hosp, Dept Surg, Div Thorac Surg, Tainan, Taiwan.; Yen, YT (通讯作者)，Natl Cheng Kung Univ Hosp, Dept Surg, Div Trauma & Acute Care Surg, Tainan, Taiwan.
EM b85401067@gmail.com
RI Yen, Yi-Ting/AAQ-1691-2020
OI Tang, Wen-Ruei/0000-0003-4006-5506
CR Andrews BT, 2006, HEAD NECK-J SCI SPEC, V28, P974, DOI 10.1002/hed.20496
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NR 39
TC 3
Z9 3
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1068-9265
EI 1534-4681
J9 ANN SURG ONCOL
JI Ann. Surg. Oncol.
PD DEC
PY 2021
VL 28
IS 13
BP 8996
EP 9007
DI 10.1245/s10434-021-10365-8
EA SEP 2021
PG 12
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA WX4LM
UT WOS:000701661100001
PM 34585295
DA 2026-07-24
ER

PT J
AU Duan, HJ
   He, YQ
   Zhang, HB
   Wang, F
   Chen, S
   Wang, J
AF Duan, Hongjie
   He, Yanqi
   Zhang, Hengbo
   Wang, Fang
   Chen, Shuai
   Wang, Jue
TI Vacuum sealing drainage with instillation in the treatment of
   necrotising soft-tissue infection: a retrospective analysis
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE debridement; necrotising soft-tissue infection; vacuum sealing drainage
   with instillation; wound healing
ID LABORATORY RISK INDICATOR; PRESSURE WOUND THERAPY; FASCIITIS
AB Objective: Necrotising soft-tissue infection is a rare but life-threatening infectious disease with high morbidity and mortality. It is typically caused by toxin-producing bacteria and characterised clinically by a very rapid progression of the disease with significant local tissue destruction. In this study, we intend to explore effective wound management to control the invasive infection and to decrease the high mortality.
   Method: This retrospective analysis explored the wound management and mortality in patients with necrotising soft-tissue infection. Extensive debridement, vacuum sealing drainage (VSD) with normal saline instillation combined with broad-spectrum or sensitive antibiotics, and supportive therapies were used.
   Results: All 17 patients included in the analysis survived. The microbiology of 11 patients was found to be polymicrobial. Of the patients, 14 were discharged with completely healed wounds and three were transferred to a local hospital after the systemic and invasive wound infection was controlled.
   Conclusion: Our experiences revealed the outstanding effect of VSD with instillation in removing the debris of necrotising tissue on the wound bed, in the continual and complete drainage of wound exudates, and in prompting wound healing.
C1 [Duan, Hongjie; He, Yanqi; Zhang, Hengbo; Wang, Fang; Chen, Shuai; Wang, Jue] Peoples Liberat Army Gen Hosp, Dept Burns & Traumat Surg, Hainan Branch, Sanya 572013, Peoples R China.
C3 Chinese People's Liberation Army General Hospital
RP Duan, HJ (通讯作者)，Peoples Liberat Army Gen Hosp, Dept Burns & Traumat Surg, Hainan Branch, Sanya 572013, Peoples R China.
EM duanhongjie@hotmail.com
RI Wang, Jue/PSM-2082-2026; Duan, Hongjie/HCI-0703-2022
OI Duan, Hongjie/0000-0001-9037-4679; Wang, Jue/0000-0003-2375-3753
FU National Natural Scientific Foundation of China [81171807]; Hainan
   Province Natural Scientific Foundation [817348]
FX The authors would like to thank all staff from the Emergency Department
   and ICU at the Hainan Branch of PLA General Hospital, Sanya, China, for
   their cooperation with monitoring and treatment. This work was supported
   partly by grants from the National Natural Scientific Foundation of
   China (#81171807) and Hainan Province Natural Scientific Foundation
   (#817348).
CR Anaya DA, 2007, CLIN INFECT DIS, V44, P705, DOI 10.1086/511638
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NR 21
TC 20
Z9 31
U1 0
U2 13
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD SEP
PY 2020
VL 29
IS 9
BP 510
EP 517
DI 10.12968/jowc.2020.29.9.510
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA NS1AC
UT WOS:000571991400006
PM 32924816
DA 2026-07-24
ER

PT J
AU Langley-Hawthorne, C
AF Langley-Hawthorne, C
TI Economics of negative pressure wound therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
C1 Eth Strategies Ltd, Oakland, CA USA.
RP Langley-Hawthorne, C (通讯作者)，Eth Strategies Ltd, Oakland, CA USA.
EM clare@ethicalstrategies.com
CR *AM POD MED ASS, 2002, AM POD MED ASS ANN S
   DRUMMOND M, 2003, VAUE HLTH, V6, P707
   LANGLEY PC, 1997, PHARMACEONOMICS ACHI
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   *WEINB GROUP INC, 1999, TECHN ASS VAC INH TR
   Weinstein MC, 2003, VALUE HEALTH, V6, P9, DOI 10.1046/j.1524-4733.2003.00234.x
NR 8
TC 3
Z9 8
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2004
SU S
BP 35
EP C3
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 817VB
UT WOS:000221203900012
PM 15317245
DA 2026-07-24
ER

PT J
AU Chen, L
   Li, D
   Lei, XD
   Zhou, BX
   Chen, LL
AF Chen, Lan
   Li, Dong
   Lei, Xiaodong
   Zhou, Bixia
   Chen, Lili
TI Evaluation of the effect of a novel nursing intervention in the
   treatment of vacuum sealing drainage in patients with chronic orthopedic
   wounds
SO AFRICAN HEALTH SCIENCES
LA English
DT Article
DE Orthopedics; chronic wounds; pattern construction; vacuum sealing
   drainage; wound care
AB Background: To explore the application effect of "4+1" nursing intervention in the treatment of chronic orthopaedic trauma with negative pressure vacuum sealing drainage.
   Methodology: Patients before the implementation of the "4+1 nursing intervention" program were selected as the control group (60 cases). 60 patients after the implementation of the "4+1 nursing intervention" program were selected as the research group. Control group was given routine care. Research group adopted the "4+1" nursing intervention. Hamilton Depression score, wound healing time, pain visual analogue scale, treatment compliance, Self-Rating Anxiety Scale, and nursing satisfaction were compared between the two groups.
   Results: After the intervention, the Self-Rating Anxiety Scale and Hamilton Depression scores in the study group were lower than those in the control group; visual analogue scale on the 3rd and 5th days after the study were lower than those in the control group, and the wound healing time was shorter than that in the control group. The treatment compliance rate and nursing satisfaction of the study group were higher than those of the control group (P<0.05).
   Conclusion: The application of "4 + 1" nursing intervention in treatment of orthopaedic chronic wounds has a good effect.
C1 [Chen, Lan; Li, Dong; Lei, Xiaodong; Zhou, Bixia; Chen, Lili] Third Peoples Hosp Chengdu, Dept Orthoped, 82 Qinglong St, Chengdu 610031, Sichuan, Peoples R China.
RP Chen, LL (通讯作者)，Third Peoples Hosp Chengdu, Dept Orthoped, 82 Qinglong St, Chengdu 610031, Sichuan, Peoples R China.
EM cdsdsrmyygk@163.com
RI zhou, bixia/HTN-5864-2023
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NR 15
TC 1
Z9 1
U1 0
U2 2
PU MAKERERE UNIV, COLL HEALTH SCIENCES,SCH MED
PI KAMPALA
PA PO BOX 7072, KAMPALA, 00000, UGANDA
SN 1680-6905
EI 1729-0503
J9 AFR HEALTH SCI
JI Afr. Health Sci.
PD DEC
PY 2024
VL 24
IS 4
DI 10.4314/ahs.v24i4.13
PG 7
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA Z7T4C
UT WOS:001440881400005
PM 40190495
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Li, TT
   Wang, GQ
   Yin, P
   Li, ZR
   Zhang, LH
   Tang, PF
AF Li, Tongtong
   Wang, Guoqi
   Yin, Peng
   Li, Zhirui
   Zhang, Lihai
   Tang, Peifu
TI Adaptive expression of biofilm regulators and adhesion factors of
   Staphylococcus aureus during acute wound infection under the
   treatment of negative pressure wound therapy in vivo
SO EXPERIMENTAL AND THERAPEUTIC MEDICINE
LA English
DT Article
DE negative pressure wound therapy; biofilm; bacterial colonization;
   Staphylococcus aureus; acute wound
ID VACUUM-ASSISTED CLOSURE; DETERMINANTS; MECHANISMS; GROWTH; MODEL
AB Negative pressure wound therapy (NPWT) is gaining acceptance as a physical therapy for a wide variety of infected wounds. To gain insight into the response of bacteria to NPWTin vivo, the adaptive expression of biofilm regulators and adhesion factors ofStaphylococcus aureus (S. aureus), the most frequently isolated pathogen in the clinic, during acute wound infection was investigated. A 3 cm full-thickness dermal wound was created on each side of a rabbit back and inoculated with green fluorescent protein-labeledS. aureus. NPWT was initiated at 6 h post inoculation, with the wound on the contralateral side as the untreated self-control. The wounds were subjected to a 28 day observation period. Histological analysis, laser scanning confocal microscopy and scanning electron microscopy revealed a transition ofS. aureusto a free-living phenotype in tissues treated with NPWT, compared with microcolonies in untreated wounds. Viable bacteria counts showed a modest reduction in the bioburden of NPWT group on day 8 (P<0.001), with similar to 1x10(6)colony-forming units/g tissue. Transcript analysis of biofilm- and colonization-related genes were investigated using reverse transcription-quantitative PCR on postoperative days 1, 2, 4 and 8. The poly-beta-1,6-N-acetyl-D-glucosamine synthase locus and holin-like protein CidA/antiholin-like protein LrgA network were less active in the NPWT group compared with the untreated control group. Accordingly, the expression profile switched to an elevated expression of the adhesive factors UDP-phosphate N-acetylglucosaminyl 1-phosphate transferase (at days 0-4) and fibronectin-binding protein A and iron-regulated surface determinant protein A at >4 days during both stages of colonization. Meanwhile, low expression levels of the effector molecule (RNAIII) of the accessory gene regulator type I (agr) system was detected in NPWT group, suggesting that the bacterial density in NPWT-treated wounds was under the threshold foragractivation, thus not leading to an active and invasive infection. The wounds treated by NPWT healed completely on day 28, compared with an average of an 8.11% defect area in the control group (P<0.001). The results of the current study indicated thatS. aureusresponds to NPWT by regulating gene expression, manifesting a decrease in biofilm formation and an increase in bacterial colonizationin vivo, which potentially benefits the wound repair and healing process.
C1 [Li, Tongtong] Tianjin Hosp, Dept Orthoped, Tianjin 300211, Peoples R China.
   [Wang, Guoqi] Chinese Peoples Liberat Army PLA Gen Hosp, Dept Pediat, Beijing 100853, Peoples R China.
   [Yin, Peng] Beijing Chao Yang Hosp, Dept Orthoped, Beijing 100043, Peoples R China.
   [Li, Zhirui; Zhang, Lihai; Tang, Peifu] Chinese Peoples Liberat Army PLA Gen Hosp, Dept Orthoped, 28 Fuxing Rd, Beijing 100853, Peoples R China.
C3 Tianjin University; Chinese People's Liberation Army General Hospital;
   Capital Medical University; Chinese People's Liberation Army General
   Hospital
RP Tang, PF (通讯作者)，Chinese Peoples Liberat Army PLA Gen Hosp, Dept Orthoped, 28 Fuxing Rd, Beijing 100853, Peoples R China.
EM tangpeifu301@sina.cn
RI Li, Zhirui/OJT-0490-2025
FU National Natural Science Foundation of China [81472112]
FX The present study was supported by the National Natural Science
   Foundation of China (grant no. 81472112).
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   Singh D, 2017, WOUNDS, V29, P175
   Song J, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0037294
   Speziale P, 2009, FUTURE MICROBIOL, V4, P1337, DOI 10.2217/FMB.09.102
   Swanson EA, 2014, JAVMA-J AM VET MED A, V244, P699, DOI 10.2460/javma.244.6.699
   Tahir S, 2018, MATERIALS, V11, DOI 10.3390/ma11050811
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   Weidenmaier C, 2008, INT J MED MICROBIOL, V298, P505, DOI 10.1016/j.ijmm.2007.11.006
NR 42
TC 8
Z9 10
U1 0
U2 14
PU SPANDIDOS PUBL LTD
PI ATHENS
PA POB 18179, ATHENS, 116 10, GREECE
SN 1792-0981
EI 1792-1015
J9 EXP THER MED
JI Exp. Ther. Med.
PD JUL
PY 2020
VL 20
IS 1
BP 512
EP 520
DI 10.3892/etm.2020.8679
PG 9
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA MM0YU
UT WOS:000549886400068
PM 32509022
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Fraccalvieri, M
   Zingarelli, E
   Ruka, E
   Antoniotti, U
   Coda, R
   Sarno, A
   Bocchiotti, MA
   Bruschi, S
AF Fraccalvieri, Marco
   Zingarelli, Enrico
   Ruka, Erind
   Antoniotti, Umberto
   Coda, Renato
   Sarno, Antonino
   Bocchiotti, Maria Alessandra
   Bruschi, Stefano
TI Negative pressure wound therapy using gauze and foam: histological,
   immunohistochemical and ultrasonography morphological analysis of the
   granulation tissue and scar tissue. Preliminary report of a clinical
   study
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Chariker-Jeter method; Foam; Gauze; Negative pressure wound therapy; VAC
   therapy
ID VACUUM-ASSISTED CLOSURE; STATE
AB Negative pressure wound therapy (NPWT) is becoming routine for the preparation of wounds prior to grafting for wound closure. We have been using both foam- and gauze-based NPWT to prepare wounds for closure prior to skin grafting and have obtained similar proportions of closed wounds; 7/7 for wounds treated with gauze-based NPWT and 11/11 for wounds treated with foam-based NPWT. In our follow-up consultations we observed that skin grafts on the foam-treated patients were less pliable than those on the gauze-treated patients. To assess what the mechanism of this effect might be, we compared the specific details of the treatments of both 11 foam and 7 gauze patients, including depth, location, patients' age and co-morbidity; biopsies of granulation and scar tissue were taken and stained with haematoxylin-eosin and by Masson's trichrome staining and conducted ultrasound analysis of the closed wounds, to see if there were features which explained those effects. All foam patients were treated at -125 mm Hg for an average of 25.9 days before skin grafts were applied. All gauze patients were treated at -80 mm Hg for an average of 24.7 days before skin grafts were applied. Biopsies of granulation tissue prior to skin grafting from five foam and four gauze-based NPWT patients did not reveal any obvious histological differences between the treatments. Ultrasound analysis of the skin-grafted wounds showed an average depth of scar tissue of 18 mm in the wound beds of the foam-treated wounds and 7 mm in the gauze-treated ones. Biopsies taken on the scar tissue after treatment with the gauze showed a minor tissue thickness and disorganisation and less sclerotic components. The findings of this preliminary analysis suggest that foam-based NPWT may induce a thicker layer of scar tissue beneath skin grafts than gauze-based NPWT which might explain a reduced pliability of the reconstructed bed. At present it is unclear which mechanism might be responsible for the difference in pressure (-125 versus -80 mm Hg), either the length of the time taken to reconstruct the wound bed or the intrinsic nature of the foam or gauze on the tissue surface. Prospective studies are necessary to investigate whether these preliminary observations are confirmed and to investigate what the mechanism might be.
C1 [Fraccalvieri, Marco; Zingarelli, Enrico; Ruka, Erind; Antoniotti, Umberto; Bocchiotti, Maria Alessandra; Bruschi, Stefano] Univ Turin, San Giovanni Battista Hosp, Dept Reconstruct & Aesthet Plast Surg, Turin, Italy.
   [Coda, Renato] Gradenigo Hosp, Dept Pathol Anat, Turin, Italy.
   [Sarno, Antonino] San Giovanni Battista Hosp, Dept Radiodiagnost, Turin, Italy.
C3 University of Turin; A.O.U. Citta della Salute e della Scienza di
   Torino; AOU San Giovanni Battista-Molinette; Humanitas Hospital
   Gradenigo; A.O.U. Citta della Salute e della Scienza di Torino; AOU San
   Giovanni Battista-Molinette
RP Fraccalvieri, M (通讯作者)，Univ Turin, San Giovanni Battista Hosp, Dept Reconstruct & Aesthet Plast Surg, Turin, Italy.
EM marco@fraccalvieri.it
RI ; /AAF-4387-2019
OI Bruschi, Stefano/0000-0002-4746-9864; Bocchiotti, Maria
   Alessana/0000-0003-0723-1074; 
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
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   *SMITH NEPH, VISTA REC US PROT
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NR 25
TC 23
Z9 32
U1 0
U2 11
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD AUG
PY 2011
VL 8
IS 4
BP 355
EP 364
DI 10.1111/j.1742-481X.2011.00798.x
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 791HB
UT WOS:000292654600006
PM 21564551
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Pouzet, L
   Lancien, U
   Hamel, A
   Perrot, P
   Duteille, F
AF Pouzet, L.
   Lancien, U.
   Hamel, A.
   Perrot, P.
   Duteille, F.
TI Negative Pressure Wound Therapy in children: A 25 cases series
SO ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE
LA English
DT Article
DE Negative Pressure Wound Therapy; Pediatric surgery; Wound; NPWT; Plastic
   pediatric surgery
ID CLOSURE; INFECTIONS; MANAGEMENT; INFANTS
AB Negative Pressure Wound Therapy is a device applied to a wound that causes local depression. There are a few series showing the effectiveness of this treatment in Pediatric. The objective of this work is to try to clarify the indications in children. This is a retrospective series of 25 children between 2004 and 2019. The inclusion criteria were all children with a wound treated with Negative Pressure Wound Therapy. The characteristics retained were their age, the context of occurrence, the treatment time, the depression applied, the technique of skin covering wound and the average healing time. We included 25 patients. The average age was 8.8 years. The context of the wound occurrence was mainly a road (44%) or a domestic (36%) accident. Substance losses were mainly located in the lower limb (84%). The depression applied was -90 mmHg. The healing time was 18.4 days. Thin skin grafting was the main method chosen (88%). No complications related to Negative Pressure Wound Therapy equipment have been identified. Despite the weakness of the literature and the lack of consensus regarding its use, Negative Pressure Wound Therapy is an essential therapy in pediatric. It is a simple and effective technique in children. It can reduce the need for flaps coverage, even in the event of exposure of noble elements. The flaps should not, however, be excluded from the decision-making algorithm, on pain of complications or sequelae. (C) 2020 Elsevier Masson SAS. All rights reserved.
C1 [Pouzet, L.; Lancien, U.; Perrot, P.; Duteille, F.] CHU Nantes, Plast & Reconstruct Surg Dept, Burns Ctr, Hotel Dieu, 30 Blvd Jean Monnet, F-44093 Nantes 1, France.
   [Hamel, A.] CHU Nantes, Pediat Orthoped Dept, Hop Mere Enfant, 38 Blvd Jean Monnet, F-44093 Nantes 1, France.
   [Pouzet, L.] CHU Reims, Plast & Reconstruct Surg Dept, Hop Maison Blanche, 45 Rue Cognacq Jay, F-51092 Reims, France.
C3 Nantes Universite; CHU de Nantes; Nantes Universite; CHU de Nantes; CHU
   de Reims; Universite de Reims Champagne-Ardenne
RP Pouzet, L (通讯作者)，CHU Reims, Plast & Reconstruct Surg Dept, Hop Maison Blanche, 45 Rue Cognacq Jay, F-51092 Reims, France.
EM lpouzet@chu-reims.fr
RI Hamel, Antoine/AAH-7437-2020; Lancien, Ugo/PNE-8797-2026
OI Hamel, Antoine/0000-0003-3348-9060; Lancien, Ugo/0000-0003-1262-5510; 
CR Aboelatta YA, 2013, J HAND MICROSURG, V5, P74, DOI 10.1007/s12593-013-0101-7
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NR 33
TC 3
Z9 3
U1 0
U2 4
PU ELSEVIER
PI BRIDGEWATER
PA 685 ROUTE 202-206, BRIDGEWATER, NJ 08807 USA
SN 0294-1260
EI 1768-319X
J9 ANN CHIR PLAST ESTH
JI Ann. Chir. Plast. Esthet.
PD JUN
PY 2021
VL 66
IS 3
BP 242
EP 249
DI 10.1016/j.anplas.2020.06.002
EA MAY 2021
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA SH7YO
UT WOS:000654349700007
PM 32665064
DA 2026-07-24
ER

PT J
AU Scalise, A
   Calamita, R
   Tartaglione, C
   Pierangeli, M
   Bolletta, E
   Gioacchini, M
   Gesuita, R
   Di Benedetto, G
AF Scalise, Alessandro
   Calamita, Roberto
   Tartaglione, Caterina
   Pierangeli, Marina
   Bolletta, Elisa
   Gioacchini, Matteo
   Gesuita, Rosaria
   Di Benedetto, Giovanni
TI Improving wound healing and preventing surgical site complications of
   closed surgical incisions: a possible role of Incisional Negative
   Pressure Wound Therapy. A systematic review of the literature
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Closed wounds; Incisional Negative Pressure Wound Therapy; Surgical
   incision; Surgical wound infection; Wound healing
ID VACUUM-ASSISTED CLOSURE; PERISTERNAL THORACIC WALL; LONG-TERM SURVIVAL;
   HIGH-RISK; CARDIAC-SURGERY; EXCESS LENGTH; BLOOD-FLOW; POSTOPERATIVE
   MEDIASTINITIS; CDC DEFINITIONS; INFECTIONS
AB Advances in preoperative care, surgical techniques and technologies have enabled surgeons to achieve primary closure in a high percentage of surgical procedures. However, often, underlying patient comorbidities in addition to surgical-related factors make the management of surgical wounds primary closure challenging because of the higher risk of developing complications. To date, extensive evidence exists, which demonstrate the benefits of negative pressure dressing in the treatment of open wounds; recently, Incisional Negative Pressure Wound Therapy (INPWT) technology as delivered by Prevena (KCI USA, Inc., San Antonio, TX) and Pico (Smith & Nephew Inc, Andover, MA) systems has been the focus of a new investigation on possible prophylactic measures to prevent complications via application immediately after surgery in high-risk, clean, closed surgical incisions. A systematic review was performed to evaluate INPWT's effect on surgical sites healing by primary intention. The primary outcomes of interest are an understanding of INPWT functioning and mechanisms of action, extrapolated from animal and biomedical engineering studies and incidence of complications (infection, dehiscence, seroma, hematoma, skin and fat necrosis, skin and fascial dehiscence or blistering) and other variables influenced by applying INPWT (re-operation and re-hospitalization rates, time to dry wound, cost saving) extrapolated from human studies. A search was conducted for published articles in various databases including PubMed, Google Scholar and Scopus Database from 2006 to March 2014. Supplemental searches were performed using reference lists and conference proceedings. Studies selection was based on predetermined inclusion and exclusion criteria and data extraction regarding study quality, model investigated, epidemiological and clinical characteristics and type of surgery, and the outcomes were applied to all the articles included. 1 biomedical engineering study, 2 animal studies, 15 human studies for a total of 6 randomized controlled trials, 5 prospective cohort studies, 7 retrospective analyses, were included. Human studies investigated the outcomes of 1042 incisions on 1003 patients. The literature shows a decrease in the incidence of infection, sero-haematoma formation and on the re-operation rates when using INPWT. Lower level of evidence was found on dehiscence, decreased in some studies, and was inconsistent to make a conclusion. Because of limited studies, it is difficult to make any assertions on the other variables, suggesting a requirement for further studies for proper recommendations on INPWT.
C1 [Scalise, Alessandro; Calamita, Roberto; Tartaglione, Caterina; Pierangeli, Marina; Bolletta, Elisa; Gioacchini, Matteo; Di Benedetto, Giovanni] Univ Politecn Marche, Dept Plast & Reconstruct Surg, Via Conca 71, I-60126 Ancona, Italy.
   [Gesuita, Rosaria] Univ Politecn Marche, Interdept Ctr Epidemiol Biostat & Med Informat EB, Ancona, Italy.
C3 Marche Polytechnic University; Marche Polytechnic University
RP Scalise, A (通讯作者)，Univ Politecn Marche, Dept Plast & Reconstruct Surg, Via Conca 71, I-60126 Ancona, Italy.
EM chiplast@univpm.it
RI ; Gesuita, Rosaria/AAU-8863-2020
OI Scalise, Alessandro/0000-0002-9198-4943; Gesuita,
   Rosaria/0000-0002-6943-0602
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NR 121
TC 186
Z9 197
U1 2
U2 29
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2016
VL 13
IS 6
BP 1260
EP 1281
DI 10.1111/iwj.12492
PG 22
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA EB8TQ
UT WOS:000387664400024
PM 26424609
OA Green Submitted
DA 2026-07-24
ER

PT J
AU DeFranzo, AJ
   Argenta, L
AF DeFranzo, AJ
   Argenta, L
TI Vacuum-assisted closure for the treatment of abdominal wounds
SO CLINICS IN PLASTIC SURGERY
LA English
DT Article
ID GROWTH-FACTOR; ELONGATION
AB Abdominal wall defects pose a significant surgical challenge. The defect may result from trauma, infections, previous major surgery or some combination of these etiologies. This article describes the Vacuum-Assisted Closure device (VAC, KCl, San Antonio, Texas) and how it can help in treating these defects.
C1 Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27157 USA.
C3 Wake Forest University
RP DeFranzo, AJ (通讯作者)，Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Med Ctr Blvd, Winston Salem, NC 27157 USA.
EM adefranz@wfubmc.edu
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NR 39
TC 19
Z9 38
U1 0
U2 0
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0094-1298
EI 1558-0504
J9 CLIN PLAST SURG
JI Clin. Plast. Surg.
PD APR
PY 2006
VL 33
IS 2
BP 213
EP +
DI 10.1016/j.cps.2005.12.007
PG 13
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 039AD
UT WOS:000237270500005
PM 16638464
DA 2026-07-24
ER

PT J
AU Morisaki, A
   Hosono, M
   Murakami, T
   Sakaguchi, M
   Suehiro, Y
   Nishimura, S
   Sakon, Y
   Yasumizu, D
   Kawase, T
   Shibata, T
AF Morisaki, Akimasa
   Hosono, Mitsuharu
   Murakami, Takashi
   Sakaguchi, Masanori
   Suehiro, Yasuo
   Nishimura, Shinsuke
   Sakon, Yoshito
   Yasumizu, Daisuke
   Kawase, Takumi
   Shibata, Toshihiko
TI Effect of negative pressure wound therapy followed by tissue flaps for
   deep sternal wound infection after cardiovascular surgery: propensity
   score matching analysis
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Deep sternal wound infection; MRSA; Negative pressure wound therapy;
   Tissue flaps
ID VACUUM-ASSISTED CLOSURE; POST-STERNOTOMY MEDIASTINITIS; POSTSTERNOTOMY
   MEDIASTINITIS; RISK-FACTORS; MUSCLE FLAP; COMPLICATIONS
AB OBJECTIVES: Deep sternal wound infection (DSWI) after cardiovascular surgery via median sternotomy remains a severe complication associated with a drastic decrease in the quality of life. We assessed the risk factors for in- hospital death caused by DSWI and the available treatments for DSWI.
   METHODS: Between January 1991 and August 2015, we retrospectively reviewed 73 patients (51 males and 22 females, mean age 67.5 +/- 10.3 years) who developed DSWI after cardiovascular surgery via median sternotomy. Pathogenic bacteria mainly comprised methicillin- resistant Staphylococcus aureus (MRSA) (49.3%). Fifteen patients (20.5%) died in hospital with DSWI. Treatment of DSWI consisted of open daily irrigation (up to 2006) or negative pressure wound therapy (NPWT) (2007 onwards), followed by primary closure or reconstruction of tissue flaps. We assessed the risk factors for in- hospital mortality from DSWI by comparing data from the 15 patients who died and the 58 survivors using propensity score matching analysis of the treatments used for DSWI.
   RESULTS: Univariate analysis identified age, use of intra-aortic balloon pumping, prolonged mechanical ventilation, tracheotomy, prolonged intensive care unit stay, postoperative low output syndrome, postoperative myocardial infarction, postoperative renal failure, postoperative use of haemodialysis, postoperative pneumonia, postoperative cerebral disorder, MRSA infection, NPWT and tissue flaps as being associated with in- hospital mortality (P < 0.05). Multivariate analysis identified NPWT (odds ratio, 0.062; 95% confidence interval, 0.004-0.897; P = 0.041) and tissue flaps (odds ratio, 0.022; 95% confidence interval, 0.000-0.960; P = 0.048) as independently associated with reduced in- hospital mortality after DSWI. On comparing 22 patients receiving NPWT with 22 not on NPWT using propensity score matching, patients on NPWT had significantly lower in- hospital mortality than those without NPWT (NPWT vs non-NPWT, 5 vs 36%, P = 0.021). In DSWI infected by MRSA, NPWT significantly reduced the in- hospital mortality caused by DSWI (NPWT vs non-NPWT, 0 vs 52%, P = 0.003).
   CONCLUSIONS: NPWT and tissue flaps may be favourable factors associated with reduced in- hospital mortality attributable to DSWI. NPWT as a bridge therapy to tissue flaps may play a major role in treating DSWI and improve the prognosis for patients withMRSA-infected DSWI.
C1 [Morisaki, Akimasa; Hosono, Mitsuharu; Murakami, Takashi; Sakaguchi, Masanori; Suehiro, Yasuo; Nishimura, Shinsuke; Sakon, Yoshito; Yasumizu, Daisuke; Kawase, Takumi; Shibata, Toshihiko] Osaka City Univ, Grad Sch Med, Dept Cardiovasc Surg, Osaka, Japan.
C3 Osaka Metropolitan University
RP Morisaki, A (通讯作者)，Osaka City Univ, Grad Sch Med, Dept Cardiovasc Surg, Abeno Ku, 1-4-3 Asahimachi, Osaka 5458585, Japan.
EM m3_514@yahoo.co.jp
RI MORISAKI, AKIMASA/ADI-0738-2022; Shibata, Toshihiko/ISB-3776-2023
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NR 24
TC 36
Z9 45
U1 0
U2 9
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
EI 1569-9285
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD SEP
PY 2016
VL 23
IS 3
BP 397
EP 402
DI 10.1093/icvts/ivw141
PG 6
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA DW8JX
UT WOS:000383902600009
PM 27199380
OA Bronze
DA 2026-07-24
ER

PT J
AU Herold, JM
   Selkridge, I
   Nocon, AA
   Bornes, TD
   Sculco, TP
   Carli, AV
   Sculco, PK
AF Herold, Johannes M.
   Selkridge, Isaiah
   Nocon, Allina A.
   Bornes, Troy D.
   Sculco, Thomas P.
   Carli, Alberto V.
   Sculco, Peter K.
TI Closed-Incision Negative Pressure Wound Therapy Improves Outcomes in
   Obese Aseptic Revision Total Hip and Knee Arthroplasty
SO JOURNAL OF ARTHROPLASTY
LA English
DT Article
DE aseptic revision; revision total knee arthroplasty; revision total hip
   arthroplasty; closed-incision negative pressure wound therapy; high-risk
   patients; obese patients; obese patients
ID TOTAL JOINT ARTHROPLASTY; VACUUM-ASSISTED CLOSURE; HOSPITAL READMISSION;
   UNITED-STATES; RISK-FACTORS; INFECTION; MORBIDITY; SURGERY;
   COMPLICATIONS; PROJECTIONS
AB Background: The burden of revision total joint arthroplasty (rTJA) is increasing. Revision procedures are associated with an increased risk of perioperative complications. Obese patients undergoing rTJA may have a higher risk of wound complications due to their soft-tissue envelope. Closed-incision negative pressure wound therapy (ciNPWT) has been rigorously investigated for its effect on reducing wound complications; however, the literature is limited to primary total joint arthroplasty. The purpose of the current study was to investigate the association between ciNPWT and clinical outcomes for obese patients undergoing aseptic revision total hip and knee arthroplasty. Methods: This was a retrospective study examining aseptic rTJA procedures from January 2017 to December 2021 at a high-volume institution. Patients were included if their body mass index was > 35 and had a minimum follow-up of 2 years. The cohorts were rTJA procedures that used ciNPWT versus procedures without ciNPWT use. A total of 214 rTJA (Hip, n = 61; Knee, n = 153) patients qualified for analysis. After surgery, ciNPWT was applied on 130 (60.7%) patients (92 knees and 38 hips), and standard dressing was used on 84 (39.3%) patients (61 knees and 23 hips). There were no significant baseline differences between the groups. Outcomes evaluated were as follows: (1) revision for infection; (2) superficial wound complications; (3) overall complications; (4) all-cause revision; and (5) all-cause readmissions. The association between ciNPWT use and outcomes was evaluated using Chi-square tests. Results: When controlling for all variables, ciNPWT use was associated with significantly fewer revisions for infection (0.8 versus 8.3%), overall complications (3.8 versus 11.9%), all-cause revisions (3.1 versus 13.1%), and readmissions (10.8 versus 21.7%) compared to those who did not use ciNPWT. Secondary superficial wound complication-specific outcomes did not show significant differences. Conclusions: To our knowledge, this study is the largest retrospective study to date examining the effect of ciNPWT on outcomes in obese aseptic revision rTJA patients. Our results demonstrated major benefits associated with the use of ciNPWT in obese patients undergoing aseptic rTJA in reference to infectionrelated revision, overall complications, all-cause revisions, and early readmission for any reason. (c) 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
C1 [Herold, Johannes M.; Selkridge, Isaiah; Nocon, Allina A.; Bornes, Troy D.; Sculco, Thomas P.; Carli, Alberto V.; Sculco, Peter K.] Hosp Special Surg, Stavros Niarchos Fdn Complex Joint Reconstruct Ctr, New York, NY USA.
   [Nocon, Allina A.; Sculco, Thomas P.; Carli, Alberto V.; Sculco, Peter K.] Hosp Special Surg, Dept Orthoped Surg, Adult Reconstruct & Joint Replacement Serv, New York, NY USA.
   [Bornes, Troy D.] Univ Alberta, Royal Alexandra Hosp, Div Orthopaed Surg, Edmonton, AB, Canada.
C3 University of Alberta; Royal Alexandra Hospital
RP Herold, JM (通讯作者)，Hosp Special Surg, Complex Joint Reconstruct Ctr, 535 East 70th St, New York, NY 10021 USA.
OI Herold, Johannes Maximilian/0009-0002-7025-3786; Usukumah-Nocon,
   Allina/0000-0003-4905-5689
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NR 48
TC 2
Z9 2
U1 0
U2 0
PU CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS
PI PHILADELPHIA
PA CURTIS CENTER, INDEPENDENCE SQUARE WEST, PHILADELPHIA, PA 19106-3399 USA
SN 0883-5403
EI 1532-8406
J9 J ARTHROPLASTY
JI J. Arthroplast.
PD JUL
PY 2025
VL 40
IS 7
SU 1
BP S271
EP S276
DI 10.1016/j.arth.2025.03.004
EA JUN 2025
PG 6
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 3ZG4V
UT WOS:001512550800041
PM 40074094
DA 2026-07-24
ER

PT J
AU Corona, PS
   Erimeiku, F
   Reverté-Vinaixa, MM
   Soldado, F
   Amat, C
   Carrera, L
AF Corona, Pablo S.
   Erimeiku, Frank
   Mercedes Reverte-Vinaixa, Maria
   Soldado, Francisco
   Amat, Carles
   Carrera, Lluis
TI Necrotising fasciitis of the extremities: implementation of new
   management technologies
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Article
DE Necrotising fasciitis; Upper extremity; Lower extremity; LRINEC;
   Negative pressure wound therapy; Hydro-bisturi debridement
ID PRESSURE WOUND THERAPY; SOFT-TISSUE INFECTIONS; LABORATORY RISK
   INDICATOR; VACUUM-ASSISTED CLOSURE; NEGATIVE-PRESSURE; HYDROSURGERY
   DEBRIDEMENT; CLINICAL PRESENTATION; SCORING SYSTEMS; LRINEC SCORE;
   DIAGNOSIS
AB Introduction: Necrotising fasciitis (NF) is potentially life-threatening soft-tissue infection. Early diagnosis and aggressive surgical debridement are critical to decrease mortality and morbidity. The impacts of new management technologies such as hydro-bisturi-assisted debridement (HAD) and negative pressure wound therapy (NPWT) are not yet clear with respect to treatment of NF. The objective of this study was to describe laboratory (including LRINEC score), clinical and microbiological factors, treatment methods and outcomes related to managing necrotising fasciitis, focusing on the implementation of new treatment methods in our centre.
   Methods: From June 2010 to June 2014, adult patients diagnosed with necrotising fasciitis affecting an upper or lower limb that were admitted to our hospital, a referral tertiary care centre, were eligible to participate in this study. Demographic data, clinical features, location of infection, Laboratory Risk Indicator for Necrotising Fasciitis (LRINEC) score on the day of admission, microbiology and laboratory results, use of HAD, wound management using NPWT, and patient outcomes were retrospectively analysed. A univariate risk factor analysis was performed, in an attempt to define prognostic factors for mortality.
   Results: A total of 20 patients satisfied the inclusion criteria. Type II NF (Group A beta-haemolytic streptococci) was found in 8 cases (40%). The average LRINEC score on the day of admission was 6. The lower extremity was affected in 60% of the cases. All patients were treated operatively, with 2.5 interventions on average. Hydro-bisturi was used in the first debridement in 40% of the cases (8 out 20). In 75% of the studied cases, Negative Pressure Wound Therapy (NPWT) was the technique selected for surgical wound management. The global mortality rate was 30%. On univariate analysis, the only factors significantly associated with mortality were high levels of creatin in (p = 0.033) and low blood glucose levels (p = 0.012). Finally, four amputations were observed in this series.
   Conclusion: We confirm that necrotising fasciitis (NF) of the extremities, despite new advancements in treatment and critical care management, is still a potentially life-threatening soft-tissue infection (30% mortality). New, advanced wound management modalities have been heavily used in management of necrotising fasciitis, but these have not had significant impacts on morbidity and mortality rates. (C) 2016 Elsevier Ltd. All rights reserved.
C1 [Corona, Pablo S.; Amat, Carles; Carrera, Lluis] Univ Autonoma Barcelona, Vall Hebron Univ Hosp, Dept Orthopaed Surg, Sept & Reconstruct Surg Unit, Pg Vall Hebron 119-129, Barcelona 08035, Spain.
   [Erimeiku, Frank; Mercedes Reverte-Vinaixa, Maria] Univ Autonoma Barcelona, Vall Hebron Univ Hosp, Dept Orthopaed Surg, Barcelona, Spain.
   [Soldado, Francisco] Hosp St Joan de Deu, Paediat Hand Surg & Microsurg Unit, Barcelona, Spain.
C3 Hospital Universitari Vall d'Hebron; Autonomous University of Barcelona;
   Autonomous University of Barcelona; Hospital Universitari Vall d'Hebron;
   University of Barcelona
RP Corona, PS (通讯作者)，Univ Autonoma Barcelona, Vall Hebron Univ Hosp, Dept Orthopaed Surg, Sept & Reconstruct Surg Unit, Pg Vall Hebron 119-129, Barcelona 08035, Spain.
EM pcorona@vhebron.net
RI Soldado, Francisco Antonio/AAR-3116-2021; Corona, Pablo S/F-7968-2012;
   Amat, Carles/E-9405-2017
OI Soldado, Francisco Antonio/0000-0003-1759-9868; Corona, Pablo
   S/0000-0003-4128-3142; Reverte-Vinaixa, Maria
   Mercedes/0000-0001-9212-7188; Amat, Carles/0000-0002-3057-0595
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NR 41
TC 25
Z9 29
U1 1
U2 10
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0020-1383
EI 1879-0267
J9 INJURY
JI Injury-Int. J. Care Inj.
PD SEP
PY 2016
VL 47
SU 3
BP S66
EP S71
DI 10.1016/S0020-1383(16)30609-X
PG 6
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA EF7VW
UT WOS:000390538400012
PM 27692110
DA 2026-07-24
ER

PT J
AU Brace, JA
AF Brace, Jacalyn A.
TI Negative pressure wound therapy for abdominal wounds
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Editorial Material
C1 Thomas Jefferson Univ Hosp, Philadelphia, PA 19107 USA.
   Univ Virginia, Charlottesville, VA USA.
C3 Thomas Jefferson University; University of Virginia
RP Brace, JA (通讯作者)，Thomas Jefferson Univ Hosp, 111 S 11th St, Philadelphia, PA 19107 USA.
EM jacalyn.brace@mail.tju.edu
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NR 6
TC 8
Z9 8
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JUL-AUG
PY 2007
VL 34
IS 4
BP 428
EP 430
DI 10.1097/01.WON.0000281661.77086.d1
PG 3
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 192HY
UT WOS:000248193100012
PM 17667091
DA 2026-07-24
ER

PT J
AU Villalba-Aguilar, C
   Carmona-Torres, JM
   Villalba-Aguilar, L
   Castillo-Hermoso, MI
   Molina-Madueño, RM
   Laredo-Aguilera, JA
AF Villalba-Aguilar, Celia
   Carmona-Torres, Juan Manuel
   Villalba-Aguilar, Lucia
   Castillo-Hermoso, Matilde Isabel
   Molina-Madueno, Rosa Maria
   Laredo-Aguilera, Jose Alberto
TI Effectiveness of Negative Pressure Wound Therapy in Burns in Pediatric
   and Adolescent Patients: A Systematic Review and Meta-Analysis
SO HEALTHCARE
LA English
DT Review
DE burn; child; negative pressure wound therapy; scar; graft; cost
ID VACUUM-ASSISTED CLOSURE; INJURIES; COSTS; CARE
AB Background: Burns represent a public health problem because they generate both physical and psychological damage, especially in the child and adolescent population, and high costs, especially due to the management of scars. Advances in burn care have improved survival and quality of life for this population. New clinical trials have been conducted on the benefits of negative pressure wound therapy (NPWT), showing that it improves the healing of burns and the appearance of scars. Therefore, this study aims to analyze the efficacy of NPWT both alone and as an adjunct to conventional dressings in pediatric and adolescent patients compared with conventional treatments. Methodology: A systematic search was carried out between December 2023 and the last quarter of 2025 in databases such as PubMed, Scopus, CINAHL, and the Cochrane Library. This meta-analysis was performed following the PRISMA statement (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and was registered in PROSPERO with registration number CRD42024597293. The risk of bias 2 (RoB2) tool was used to assess the risk of bias in the studies. Quantitative meta-analyses using random-model effects were performed only for variables with sufficient comparable data among studies. For other outcomes, where meta-analysis was not feasible due to lack of comparable data or control groups, results were synthesized qualitatively. Results: A total of seven articles (three clinical trials and four retrospective studies), in which a total of 323 subjects participated, were included. The main results demonstrate the efficacy of NPWT, as it decreases the re-epithelialization time, improves the appearance of scars (MD = -1.25 (95% CI between -1.80 and -0.70)), reduces the probability of skin grafts (OR = 0.17 (95% CI between 0.06 and 0.46)), and therefore, as there is less need for surgery and fewer dressing changes, reduces costs. Conclusions: NPWT offers significant clinical benefits in the treatment of burns in children and adolescents. Although a meta-analysis could not be performed due to the lack of a control group in some studies, studies with larger samples and multicenter designs will be necessary to better assess the relevant clinical outcomes. However, the results of this study show that NPWT is effective in treating burns in children and adolescents and that its use in clinical practice may represent a promising adjunctive therapy.
C1 [Villalba-Aguilar, Celia] Hosp Laboral Solimat, Calle San Pedro el Verde 35, Toledo 45004, Spain.
   [Villalba-Aguilar, Celia; Carmona-Torres, Juan Manuel; Castillo-Hermoso, Matilde Isabel; Molina-Madueno, Rosa Maria; Laredo-Aguilera, Jose Alberto] Univ Castilla La Mancha, Fac Fisioterapia & Enfermeria Toledo, Avda Carlos 3 S-N, Toledo 45071, Spain.
   [Carmona-Torres, Juan Manuel; Laredo-Aguilera, Jose Alberto] Univ Castilla La Mancha, Grp Invest Multidisciplinar Cuidados IMCU, Avda Carlos 3 S-N, Toledo 45071, Spain.
   [Carmona-Torres, Juan Manuel; Laredo-Aguilera, Jose Alberto] Inst Invest Sanitaria Castilla La Mancha IDISCAM, Finca Peraleda S-N, Toledo 45004, Spain.
   [Villalba-Aguilar, Lucia] Univ Rey Juan Carlos, Fac Ciencias Salud, Alcorcon 28922, Spain.
   [Castillo-Hermoso, Matilde Isabel] Hosp Nacl Paraplej, Finca Peraleda S-N, Toledo 45004, Spain.
C3 Universidad de Castilla-La Mancha; Universidad de Castilla-La Mancha;
   Universidad Rey Juan Carlos; Hospital Nacional de Paraplejicos
RP Carmona-Torres, JM (通讯作者)，Univ Castilla La Mancha, Fac Fisioterapia & Enfermeria Toledo, Avda Carlos 3 S-N, Toledo 45071, Spain.; Carmona-Torres, JM (通讯作者)，Univ Castilla La Mancha, Grp Invest Multidisciplinar Cuidados IMCU, Avda Carlos 3 S-N, Toledo 45071, Spain.; Carmona-Torres, JM (通讯作者)，Inst Invest Sanitaria Castilla La Mancha IDISCAM, Finca Peraleda S-N, Toledo 45004, Spain.
EM celia.villalba@alu.uclm.es; juanmanuel.carmona@uclm.es;
   luciavillalbaaguilar12@gmail.com; matildei.castillo@uclm.es;
   rosam.molina@uclm.es; josealberto.laredo@uclm.es
RI Carmona-Torres, Juan/E-1579-2018; Laredo, José/ABR-3810-2022; Castillo
   Hermoso, Matilde/LTF-0979-2024
OI Villalba Aguilar, Celia/0009-0003-2766-224X; Molina Madueño, Rosa
   María/0000-0002-5085-8377
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NR 52
TC 0
Z9 0
U1 1
U2 1
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2227-9032
J9 HEALTHCARE-BASEL
JI Healthcare
PD JAN 19
PY 2026
VL 14
IS 2
AR 242
DI 10.3390/healthcare14020242
PG 23
WC Health Care Sciences & Services; Health Policy & Services
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Health Care Sciences & Services
GA CO3IB
UT WOS:001670544700001
PM 41595378
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Fackler, ML
AF Fackler, Martin L.
TI Vacuum-assisted closure of the abdomen
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Letter
CR Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
NR 1
TC 2
Z9 5
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1072-7515
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD FEB
PY 2008
VL 206
IS 2
BP 400
EP 400
DI 10.1016/j.jamcollsurg.2007.11.009
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 257UA
UT WOS:000252822900031
PM 18222401
DA 2026-07-24
ER

PT J
AU Pang, PC
   Liu, YH
   Song, HC
   Ye, ZF
   Zhou, H
   Zhang, R
   Kumeria, T
   She, WT
   Xu, C
   Mei, PL
   He, Y
   Ye, QS
AF Pang, Pengcheng
   Liu, Yonghao
   Song, Haicheng
   Ye, Zhifei
   Zhou, Heng
   Zhang, Rui
   Kumeria, Tushar
   She, Wenting
   Xu, Chun
   Mei, Peter L.
   He, Yan
   Ye, Qingsong
TI Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for
   Diabetic Wound Healing
SO DIABETES
LA English
DT Article
ID SMALL EXTRACELLULAR VESICLES; MITOCHONDRIAL-DNA RELEASE; MACROPHAGE
   POLARIZATION; RECOVERY; LYSATE; ACTIVATION
AB Diabetic wounds represent a significant clinical and economic burden, affecting both patients and health care systems. While current therapeutic approaches, such as negative pressure wound therapy, offer benefits, their limitations necessitate alternative strategies. Newly discovered dental pulp stem cell-derived intracellular vesicles have emerged as a promising candidate in regenerative medicine due to their therapeutic potential. In vitro assessments using HUVECs, HaCaTs, and RAW264.7 cells revealed that intracellular vesicles enhance cell migration, angiogenesis, and proliferation while suppressing the cGAS-STING pathway. Additionally, intracellular vesicles promoted M2 macrophage polarization and maintained mitochondrial function. In a diabetic mouse wound model, both intracellular vesicles and negative pressure wound therapy individually improved wound healing, but their combination exhibited a synergistic effect, resulting in faster wound closure, enhanced angiogenesis, and reduced inflammation. The combined treatment also exhibited excellent biocompatibility. These findings highlight the therapeutic potential of intracellular vesicles as an adjunct to negative pressure wound therapy for diabetic wound treatment.Article Highlights Chronic diabetic wounds are difficult to heal, and current treatments, such as negative pressure wound therapy, have limited effectiveness. The potential of intracellular vesicles derived from dental pulp stem cell lysate for diabetic wound healing is well worth exploring. Intracellular vesicles promoted angiogenesis, cell proliferation, and M2 macrophage polarization by inhibiting cGAS-STING signaling and restoring mitochondrial function. Combined with negative pressure wound therapy, intracellular vesicles accelerated wound healing in diabetic mice. Intracellular vesicles offer a promising cell-free strategy to enhance negative pressure wound therapy outcomes and improve diabetic wound treatment.
C1 [Pang, Pengcheng; Liu, Yonghao; Song, Haicheng; Ye, Zhifei; Zhou, Heng; Zhang, Rui; She, Wenting; Ye, Qingsong] Wuhan Univ, Renmin Hosp, Ctr Regenerat Med, Dept Stomatol, Wuhan, Peoples R China.
   [Kumeria, Tushar] Univ New South Wales, Sch Mat Sci & Engn, Kensington, NSW, Australia.
   [Xu, Chun; Ye, Qingsong] Univ Sydney, Sydney Sch Dent, Sydney, NSW, Australia.
   [Mei, Peter L.] Univ Otago, Fac Dent, Dept Orthodont, Dunedin, Otago, New Zealand.
   [He, Yan] Harvard Sch Med, Massachusetts Gen Hosp, Dept Oral & Maxillofacial Surg, Boston, MA USA.
   [He, Yan] Wuhan Univ Sci & Technol, Tianyou Hosp, Inst Regenerat & Translat Med, Wuhan, Hubei, Peoples R China.
C3 Wuhan University; University of New South Wales Sydney; University of
   Sydney; University of Otago; Harvard University; Harvard Medical School;
   Harvard University Medical Affiliates; Massachusetts General Hospital;
   Wuhan University of Science & Technology
RP Ye, QS (通讯作者)，Wuhan Univ, Renmin Hosp, Ctr Regenerat Med, Dept Stomatol, Wuhan, Peoples R China.; Ye, QS (通讯作者)，Univ Sydney, Sydney Sch Dent, Sydney, NSW, Australia.
EM qingsongye@whu.edu.cn
RI Pang, pengcheng/MGV-5338-2025; Xu, Chun/C-3649-2017
OI Xu, Chun/0000-0001-8831-3607
FU Qingsong Ye [2022YFC2504200,2022BCA029]
FX Funding. This work was financially supported by the Key Project of
   Ministry of Science and Technology China (grant 2022YFC2504200 to Q.Y.)
   and Key Research and Development Project of Hubei Province (grant
   2022BCA029 to Q.Y.).
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NR 49
TC 2
Z9 2
U1 11
U2 16
PU AMER DIABETES ASSOC
PI ALEXANDRIA
PA 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA
SN 0012-1797
EI 1939-327X
J9 DIABETES
JI Diabetes
PD NOV
PY 2025
VL 74
IS 11
DI 10.2337/db24-0686
PG 16
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA EE2BH
UT WOS:001698970600027
PM 40906538
DA 2026-07-24
ER

PT J
AU Mo, JM
   Huang, YJ
   Wang, Q
   Zhong, H
   Zhai, ZW
   Nong, YC
   Yan, XD
   Huang, XL
   Huang, JH
   Yang, SP
   Sun, JX
   Han, JX
   Zhou, X
   Lu, WS
AF Mo, Jianming
   Huang, Yuanjing
   Wang, Qiu
   Zhong, Hua
   Zhai, Zhenwei
   Nong, Yuechou
   Yan, Xiaodong
   Huang, Xiulu
   Huang, Jianhao
   Yang, Suping
   Sun, Jingxia
   Han, Jiaxia
   Zhou, Xing
   Lu, Wensheng
TI Autologous wound margin point columnar full-thickness skin grafting
   combined with negative pressure wound therapy improves wound healing in
   refractory diabetic foot ulcers
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE autologous full-thickness skin graft; diabetic lower extremity ulcers;
   negative pressure wound therapy; refractory wound
ID VACUUM-ASSISTED CLOSURE; LOWER-EXTREMITY ULCERS; BLOOD-FLOW;
   PROLIFERATION; COMPLICATIONS; MELLITUS; DISEASE; IMPACT; CELLS
AB Diabetic lower extremity ulcers (DLEUs) are a severe complication of diabetes mellitus (DM) and are difficult to heal. This study aimed to explore the efficacy of autologous point columnar full-thickness skin graft taken from the ulcer wound margin combined with negative pressure wound therapy (NPWT) in refractory DLEUs. This is a prospective cohort study. A total of 40 inpatients with refractory DLEUs were recruited in the Diabetes Foot Center of Guangxi Zhuang Autonomous Region People's Hospital from October 2019 to November 2021. According to the doctors' professional suggestions and the patients' personal wishes, these enrolled patients were divided into two groups based on different topical wound management: the graft group (n = 18) and the conventional wound therapeutic (CWT) group (n = 22). The efficacy evaluations included the time to complete re-epithelialization of the wound and healing speed within 14 days of graft treatment or after 14 days of graft treatment in the two groups. Before the treatment, the graft group had a significantly larger ulcer area than the CWT group [27.22 (15.28, 46.59) versus 10.92 (7.00, 24.93) cm(2), P < .01]. However, the time to complete wound re-epithelialization in the graft group was shorter than in the CWT group [58.22 +/- 30.60 versus 86.09 +/- 49.54 d, P < .05]. Meanwhile, the healing speed in graft group was markedly faster than in CWT group, whether within 14 days [0.60 (0.40, 0.92) versus 0.16 (0.07, 0.34) cm(2)/d, P < .01] or after 14 days of graft treatment [0.57 (0.45, 0.91) versus 0.13 (0.08, 0.27) cm(2)/d, P < .01]. However, the total treatment cost in the graft group was lower than in the CWT group [419.59 +/- 137.20 versus 663.97 +/- 497.02 $, P < .05]. The novel treatment modality of autologous full-thickness skin graft taken from the ulcer wound margin combined with NPWT has hereby proposed for the first time, and is a safe, effective, and reliable method with a good performance-to-cost ratio to promote wound healing and shorten the healing time for DLEUs.
C1 [Mo, Jianming] Jinan Univ, Dept Endocrinol & Metab, Guangzhou, Peoples R China.
   [Mo, Jianming; Wang, Qiu; Zhong, Hua; Zhai, Zhenwei; Nong, Yuechou; Yan, Xiaodong; Huang, Xiulu; Huang, Jianhao; Sun, Jingxia; Han, Jiaxia; Zhou, Xing; Lu, Wensheng] Guangxi Acad Med Sci, Dept Endocrinol & Metab, Nanning 530021, Guangxi, Peoples R China.
   [Mo, Jianming; Huang, Yuanjing; Wang, Qiu; Zhong, Hua; Zhai, Zhenwei; Nong, Yuechou; Yan, Xiaodong; Huang, Xiulu; Huang, Jianhao; Yang, Suping; Sun, Jingxia; Han, Jiaxia; Zhou, Xing; Lu, Wensheng] Peoples Hosp Guangxi Zhuang Autonomous Reg, Nanning 530021, Guangxi, Peoples R China.
   [Huang, Yuanjing; Yang, Suping] Guangxi Acad Med Sci, Hlth Management Ctr, Nanning, Guangxi, Peoples R China.
C3 Jinan University
RP Lu, WS (通讯作者)，Guangxi Acad Med Sci, Dept Endocrinol & Metab, Nanning 530021, Guangxi, Peoples R China.; Lu, WS (通讯作者)，Peoples Hosp Guangxi Zhuang Autonomous Reg, Nanning 530021, Guangxi, Peoples R China.
EM lws2613676@sohu.com
RI Wang, Rundong/LTY-8296-2024; Yan, Xiaodong/KFO-2574-2024; lu,
   wensheng/AAW-7161-2021; lu, wensheng/AAW-7161-2021
OI lu, wensheng/0000-0003-4179-1171; lu, wensheng/0000-0002-0212-3624
FU Guangxi Medical and Health Appropriate Technology Research and
   Development Project [S201422-01]; Natural Science Foundation of China
   [82160052, 81560044, 30860113]; Shanxi Health Research Project [2019165]
FX Guangxi Medical and Health Appropriate Technology Research and
   Development Project, Grant/Award Number: S201422-01; Natural Science
   Foundation of China, Grant/Award Numbers: 82160052, 81560044, 30860113;
   Shanxi Health Research Project, Grant/Award Number: 2019165
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NR 53
TC 9
Z9 11
U1 1
U2 29
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAY
PY 2023
VL 20
IS 5
BP 1506
EP 1516
DI 10.1111/iwj.14005
EA OCT 2022
PG 11
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA D5KM3
UT WOS:000875308400001
PM 36307147
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Joo, HS
   Lee, SJ
   Lee, SY
   Sung, KY
AF Joo, Hong Sil
   Lee, Seung Je
   Lee, Sang-Yeul
   Sung, Kun Yong
TI The Efficacy of Negative Pressure Wound Therapy for Split-thickness Skin
   Grafts for Wounds on the Trunk or the Neck: A Randomized Controlled
   Trial
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE split-thickness skin graft; negative pressure wound therapy;
   conventional bolster dressing
ID VACUUM-ASSISTED CLOSURE; EXPERIENCE; RUBBER; TIE
AB Introduction. Because applying a splint for a wound on a patient's trunk or neck (including areas such as the shoulder, chest, buttock, axilla, and abdomen) is considerably difficult, grafted skin may not firmly affix at the wound site. Objective. A study was conducted to compare negative pressure wound therapy (NPWT) to conventional bolster dressings in facilitating firm split-thickness skin graft (STSG) attachment and allowing relatively easy removal of exudates. Materials and Methods. A randomized controlled trial was conducted among 57 patients with wounds on the trunk or the neck who received STSGs between January 2013 and December 2017. Prospective and retrospective data were used for analysis in this study. Patients who were pregnant, immunocompromised, or had severely infected wounds were excluded from the study. Due to discomfort, splints were not used. Patients were divided into 2 groups. Group 1 was provided a NPWT dressing; NPWT was applied continuously for 6 days between -75 mm Hg and -100 mm Hg with dressing changes at postoperative days 3 and 6. After postoperative day 6, antibiotic cream and a nonadherent foam dressing were used on the wounds. Group 2 was provided a conventional bolster dressing for the same time frame. The Mann-Whitney U test was used to compare the variables and outcomes between the 2 groups. Differences were considered statistically significant for P<.05. Results. Among the 57 patients, 27 received NPWT and 30 received the bolster dressing. The size of the wounds in these patients ranged between 100 cm(2) and 400 cm(2). In group 1, the average survival score for the skin graft was more than 80 in all patients after postoperative day 7. In group 2, major graft loss occurred in 5 patients, requiring a second STSG. The average score of STSG survival on postoperative day 7 in group 2 was lower than that of group 1. The differences observed between the 2 groups were overall statistically significant (P < .01) based on the results of the Mann-Whitney U test. Conclusions. Owing to the flexibility and elasticity afforded by the transparent adhesive film that is used in NPWT technique, patients were more mobile and felt little discomfort compared to conventional procedures. The negative pressure dressing increased the percentage of graft survival and may reduce need for a second STSG.
C1 [Joo, Hong Sil; Lee, Seung Je] Hanil Gen Hosp, Dept Plast & Reconstruct Surg, Seoul, South Korea.
   [Lee, Sang-Yeul; Sung, Kun Yong] Kangwon Natl Univ, Chunchon, South Korea.
C3 Kangwon National University
RP Sung, KY (通讯作者)，Kangwon Natl Univ, Med, 1 Kangwondaehak Gil, Chuncheon Si 24341, Kangwondo, South Korea.
EM ps@kangwon.ac.kr
CR [Anonymous], 2017, J WOUND MANAGEMENT R, DOI DOI 10.22467/
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NR 22
TC 3
Z9 4
U1 0
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD DEC
PY 2020
VL 32
IS 12
BP 334
EP 338
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA QI0SU
UT WOS:000618686200002
PM 33465041
DA 2026-07-24
ER

PT J
AU Zens, Y
   Barth, M
   Bucher, HC
   Dreck, K
   Felsch, M
   Gross, W
   Jaschinski, T
   Kölsch, H
   Kromp, M
   Overesch, I
   Sauerland, S
   Gregor, S
AF Zens, Yvonne
   Barth, Michael
   Bucher, Heiner C.
   Dreck, Katrin
   Felsch, Moritz
   Gross, Wolfram
   Jaschinski, Thomas
   Kolsch, Heike
   Kromp, Mandy
   Overesch, Inga
   Sauerland, Stefan
   Gregor, Sven
TI Negative pressure wound therapy in patients with wounds healing by
   secondary intention: a systematic review and meta-analysis of randomised
   controlled trials
SO SYSTEMATIC REVIEWS
LA English
DT Review
DE Negative-pressure wound therapy; Wound healing; Benefit assessment;
   Systematic review; Publication bias
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; CHRONIC LEG ULCERS;
   QUALITY-OF-LIFE; THICKNESS SKIN-GRAFTS; THE-ART TREATMENT; OPEN ABDOMEN;
   CLINICAL-TRIAL; OPEN FRACTURE; MANAGEMENT
AB Background: Negative pressure wound therapy (NPWT) is a widely used method of wound treatment. We performed a systematic review of randomised controlled trials (RCTs) comparing the patient-relevant benefits and harms of NPWT with standard wound therapy (SWT) in patients with wounds healing by secondary intention.
   Methods: We searched for RCTs in MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, and study registries (last search: July 2018) and screened reference lists of relevant systematic reviews and health technology assessments. Manufacturers and investigators were asked to provide unpublished data. Eligible studies investigated at least one patient-relevant outcome (e.g. wound closure). We assessed publication bias and, if feasible, performed meta-analyses, grading the results into different categories (hint, indication or proof of a greater benefit or harm).
   Results: We identified 48 eligible studies of generally low quality with evaluable data for 4315 patients and 30 eligible studies with missing data for at least 1386 patients. Due to potential publication bias (proportion of inaccessible data, 24%), we downgraded our conclusions. A meta-analysis of all wound healing data showed a significant effect in favour of NPWT (OR 1.56, 95% CI 1.15 to 2.13, p = 0.008). As further analyses of different definitions of wound closure did not contradict that analysis, we inferred an indication of a greater benefit of NPWT. A meta-analysis of hospital stay (in days) showed a significant difference in favour of NPWT (MD - 4.78, 95% CI - 7.79 to - 1.76, p = 0.005). As further analyses of different definitions of hospital stay/readmission did not contradict that analysis, we inferred an indication of a greater benefit of NPWT. There was neither proof (nor indication nor hint) of greater benefit or harm of NPWT for other patient-relevant outcomes such as mortality and adverse events.
   Conclusions: In summary, low-quality data indicate a greater benefit of NPWT versus SWT for wound closure in patients with wounds healing by secondary intention. The length of hospital stay is also shortened. The data show no advantages or disadvantages of NPWT for other patient-relevant outcomes. Publication bias is an important problem in studies on NPWT, underlining that all clinical studies need to be fully reported.
C1 [Zens, Yvonne; Dreck, Katrin; Felsch, Moritz; Gross, Wolfram; Jaschinski, Thomas; Kolsch, Heike; Kromp, Mandy; Overesch, Inga; Sauerland, Stefan] Inst Qual & Efficiency Hlth Care IQWiG, Mediapk 8, D-50670 Cologne, Germany.
   [Bucher, Heiner C.] Univ Hosp Basel, Basel Inst Clin Epidemiol & Biostat, Basel, Switzerland.
   [Bucher, Heiner C.] Univ Basel, Basel, Switzerland.
C3 University of Basel; Swiss School of Public Health (SSPH+); University
   of Basel
RP Zens, Y (通讯作者)，Inst Qual & Efficiency Hlth Care IQWiG, Mediapk 8, D-50670 Cologne, Germany.
EM Yvonne.Zens@iqwig.de
OI Zens, Yvonne/0000-0002-6301-9361
FU Projekt DEAL
FX Open Access funding enabled and organized by Projekt DEAL.
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NR 149
TC 44
Z9 56
U1 0
U2 16
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 2046-4053
J9 SYST REV-LONDON
JI Syst. Rev.
PD OCT 10
PY 2020
VL 9
IS 1
AR 238
DI 10.1186/s13643-020-01476-6
PG 26
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA OB6UB
UT WOS:000578603300003
PM 33038929
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU García-Marirrodriga, I
   Ruiz, SF
   Matías, AH
   Gil, JB
   Esteban, ML
AF Garcia-Marirrodriga, I.
   Fuerte Ruiz, S.
   Hernandez Matias, A.
   Bouzada Gil, J.
   Limones Esteban, M.
TI Vacuum-assisted closure of abdominal wounds
SO OBESITY SURGERY
LA English
DT Meeting Abstract
CT 9th Congress of the Spanish-Society-for-the-Surgery-of-Obesity
CY MAR 07-09, 2007
CL Getafe Madrid, SPAIN
SP Spanish Soc Surg Obes
C1 Univ Hosp, Madrid, Spain.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU F D-COMMUNICATIONS INC
PI TORONTO
PA 3100 BAYVIEW AVE, UNIT 4, TORONTO, ONTARIO M2N 5L3, CANADA
SN 0960-8923
J9 OBES SURG
JI Obes. Surg.
PD FEB
PY 2007
VL 17
IS 2
MA 5
BP 272
EP 272
PG 1
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 137OF
UT WOS:000244301200031
DA 2026-07-24
ER

PT J
AU Madura, J
AF Madura, Judy
TI NEGATIVE PRESSURE WOUND THERAPY FOR FISTULA MANAGEMENT?
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Madura, Judy] Good Samaritan Wound Care Ctr, Phoenix, AZ USA.
EM Judith.Madura@bannerhealth.com
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2010
VL 37
IS 3
SU S
BP S38
EP S38
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 600RG
UT WOS:000278004200100
DA 2026-07-24
ER

PT J
AU Nguyen, KA
   Taylor, GA
   Webster, TK
   Jenkins, RA
   Houston, NS
   Kahler, DL
   Gassman, AA
   Jones, CM
AF Nguyen, Kaitlin A.
   Taylor, George A.
   Webster, Theresa K.
   Jenkins, Rachel A.
   Houston, Nicklaus S.
   Kahler, Dylan L.
   Gassman, Andrew A.
   Jones, Christine M.
TI Incisional Negative Pressure Wound Therapy Is Protective Against
   Postoperative Cardiothoracic Wound Infection
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE closed incision negative pressure therapy; ciNPT; wound healing; wound
   infection; sternal wound; Prevena
ID MANAGEMENT; RISK; STATINS; IMPACT
AB Background Sternal wound infections are a rare but life-threatening complication of cardiothoracic surgery. Prior literature has supported the use of negative pressure wound therapy to decrease sternal wound infections and promote healing. This study sought to determine whether closed incision negative pressure therapy reduced wound infection and improved outcomes in cardiothoracic surgery. Methods A retrospective cohort study was performed including all adult patients who underwent nontraumatic cardiothoracic surgery at a single institution between 2016 and 2018 (n = 1199). Patient characteristics, clinical variables, and surgical outcomes were compared between those who did and did not receive incisional negative pressure wound therapy intraoperatively. Multivariable logistic regression analysis determined factors predictive or protective of the development of complications. Results Incisional negative pressure wound therapy was used in 58.9% of patients. Patients who received this therapy were older with statistically higher rates of hyperlipidemia, statin, and antihypertensive use. The use of negative pressure wound therapy was found to significantly reduce rates of both wound infection (3.0% vs 6.3%, P = 0.01) and readmission for wound infection (0.7% vs 2.6%, P = 0.01). After controlling for confounding variables, negative pressure wound therapy was found to be a protective factor of surgical wound infection (odds ratio, 0.497; 95% confidence interval, 0.262-0.945). Conclusions In the largest population studied to date, this study supported the expanded use of negative pressure therapy on sternal wound incisions to decrease infection rates.
C1 [Nguyen, Kaitlin A.; Taylor, George A.; Webster, Theresa K.; Jenkins, Rachel A.; Houston, Nicklaus S.; Kahler, Dylan L.; Jones, Christine M.] Temple Univ Hosp & Med Sch, Dept Surg, 3401 N Broad St, Philadelphia, PA 19140 USA.
   [Gassman, Andrew A.] PRMA Plast Surg Ctr Adv Reconstruct, San Antonio, TX USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple
   University
RP Nguyen, KA; Jones, CM (通讯作者)，Temple Univ Hosp & Med Sch, Dept Surg, 3401 N Broad St, Philadelphia, PA 19140 USA.
EM kaitlin.nguyen@temple.edu; christine.jones@tuhs.temple.edu
RI ; Taylor, George/GLV-2344-2022
OI Jones, Christine/0000-0002-6333-8039; Nguyen,
   Kaitlin/0000-0002-9563-0106; 
CR [Anonymous], PREVENA INCISION MAN
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NR 19
TC 6
Z9 7
U1 2
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD MAY
PY 2022
VL 88
IS 3
SU 3
BP S197
EP S200
DI 10.1097/SAP.0000000000003196
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 0Z3SX
UT WOS:000791002000013
PM 35513319
DA 2026-07-24
ER

PT J
AU Kline, B
   Olecki, E
   Brinton, D
   Koltun, W
AF Kline, B.
   Olecki, E.
   Brinton, D.
   Koltun, W.
TI NEGATIVE PRESSURE WOUND THERAPY AFTER OSTOMY CLOSURE.
SO DISEASES OF THE COLON & RECTUM
LA English
DT Meeting Abstract
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD JUN
PY 2020
VL 63
IS 6
MA P1234
BP E265
EP E266
PG 2
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA LO8LL
UT WOS:000533877100434
DA 2026-07-24
ER

PT J
AU Schlatterer, D
   Webb, LX
AF Schlatterer, D
   Webb, LX
TI Orthopedic indications for negative pressure wound therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article; Proceedings Paper
CT National Vacuum-Assisted Closure Education Conference
CY NOV 05-07, 2004
CL Los Angeles, CA
CR Morykwas MJ, 1999, J BURN CARE REHABIL, V20, P15, DOI 10.1097/00004630-199901001-00003
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Webb LX, 2001, UNFALLCHIRURG, V104, P918, DOI 10.1007/PL00002776
NR 3
TC 2
Z9 7
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD FEB
PY 2005
SU S
BP 27S
EP 28S
PG 2
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Dermatology; Surgery
GA 906AP
UT WOS:000227613200006
PM 15699561
DA 2026-07-24
ER

PT J
AU Webster, R
   Ely, PB
   Milani, A
   Pereira, G
   Valiati, A
   Minuzzi, A
   Cunha, T
   Rech, D
AF Webster, Ronaldo
   Ely, Pedro Bins
   Milani, Adriana
   Pereira Filho, Gustavo
   Valiati, Andre
   Minuzzi Filho, Antonio
   Cunha, Tiago
   Rech, Darwin
TI Alternative Materials in Vacuum-Assisted Closure
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Letter
C1 [Webster, Ronaldo; Ely, Pedro Bins; Milani, Adriana; Pereira Filho, Gustavo; Valiati, Andre; Minuzzi Filho, Antonio; Cunha, Tiago; Rech, Darwin] Fed Univ Hlth Sci Porto Alegre, BR-90035210 Porto Alegre, RS, Brazil.
RP Webster, R (通讯作者)，Fed Univ Hlth Sci Porto Alegre, BR-90035210 Porto Alegre, RS, Brazil.
EM ronaldowebster@hotmail.com
CR Dastouri P, 2011, PLAST RECONSTR SURG, V127, P1460, DOI 10.1097/PRS.0b013e31820a63cb
NR 1
TC 3
Z9 5
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0032-1052
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD DEC
PY 2011
VL 128
IS 6
BP 784E
EP 785E
DI 10.1097/PRS.0b013e318230be64
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 852DU
UT WOS:000297329700038
PM 22094790
DA 2026-07-24
ER

PT J
AU Matsumoto, K
   Furukawa, M
   Sato, S
AF Matsumoto, K.
   Furukawa, M.
   Sato, S.
TI NEGATIVE PRESSURE WOUND THERAPY FOR DIABETIC ULCERS
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Matsumoto, K.; Furukawa, M.; Sato, S.] Oitaoka Hosp, Dept Plast Surg, Wound Care Ctr, Oita, Japan.
NR 0
TC 0
Z9 0
U1 0
U2 2
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JAN-FEB
PY 2015
VL 23
IS 1
MA PD1-03
BP A1
EP A1
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA CH0DP
UT WOS:000353689600002
DA 2026-07-24
ER

PT J
AU Wallis, L
AF Wallis, Laura
TI FDA Warning About Negative Pressure Wound Therapy
SO AMERICAN JOURNAL OF NURSING
LA English
DT News Item
NR 0
TC 12
Z9 12
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0002-936X
J9 AM J NURS
JI Am. J. Nurs.
PD MAR
PY 2010
VL 110
IS 3
BP 16
EP 16
DI 10.1097/01.NAJ.0000368938.90936.17
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 622VB
UT WOS:000279692800007
DA 2026-07-24
ER

PT J
AU Uhl, RL
AF Uhl, Richard L.
TI Vacuum-assisted Closure for Hand Injuries
SO ORTHOPEDICS
LA English
DT Editorial Material
C1 Albany Med Coll, Div Orthopaed Surg, Albany, NY 12206 USA.
C3 Albany Medical College
RP Uhl, RL (通讯作者)，Albany Med Coll, Div Orthopaed Surg, 1367 Washington Ave,Ste 200, Albany, NY 12206 USA.
EM uhlr@aol.com
RI /U-6751-2019
NR 0
TC 1
Z9 1
U1 0
U2 1
PU SLACK INC
PI THOROFARE
PA 6900 GROVE RD, THOROFARE, NJ 08086 USA
SN 0147-7447
EI 1938-2367
J9 ORTHOPEDICS
JI Orthopedics
PD OCT
PY 2013
VL 36
IS 10
BP 773
EP 774
DI 10.3928/01477447-20130920-05
PG 2
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 247QI
UT WOS:000326633500025
PM 24093689
DA 2026-07-24
ER

PT J
AU Madura, J
   Murphy, W
AF Madura, Judy
   Murphy, Wendy
TI NEGATIVE PRESSURE WOUND THERAPY FOR FISTULA MANAGEMENT?
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Madura, Judy] Good Samaritan Wound Care Ctr, Phoenix, AZ USA.
   [Murphy, Wendy] Banner Good Samaritan Wound Care Program, Phoenix, AZ USA.
C3 Banner Research; Banner Health
EM judyamadura@hotmail.com; Wendy.Murphy@bannerhealth.com
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2009
VL 36
IS 3
BP S24
EP S24
DI 10.1097/01.WON.0000351953.38458.83
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 446KH
UT WOS:000266120000068
DA 2026-07-24
ER

PT J
AU Kuang, XW
   Liang, ZY
   Xia, YJ
   Shan, MJ
   Hao, Y
   Liu, H
   Wang, Z
   He, QJ
   Xia, C
   Feng, C
   Chang, GJ
   Wang, YB
AF Kuang, Xinwen
   Liang, Zhengyun
   Xia, Yijun
   Shan, Mengjie
   Hao, Yan
   Liu, Hao
   Wang, Zhi
   He, Qianjun
   Xia, Chao
   Feng, Cheng
   Chang, Guojing
   Wang, Youbin
TI Hydrogen-Rich Saline Combined With Vacuum Sealing Drainage Promotes
   Wound Healing by Altering Biotin Metabolism
SO JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
LA English
DT Article
DE biotin metabolism; hydrogen-rich saline; metabolomics; oxidative stress;
   vacuum sealing drainage; wound healing
ID WATER PROTECTS; PRESSURE; INFLAMMATION; MECHANISM; CYTOKINES; HEALTHY;
   INJURY; DAMAGE; MICE
AB Impaired wound healing affects the life quality of patients and causes a substantial financial burden. Hydrogen-rich medium is reported to have antioxidant and anti-inflammatory effects. However, the role of hydrogen-rich saline (HRS) in cutaneous wound healing remains largely unexplored, especially by metabolomics. Thus, untargeted metabolomics profiling was analysed to study the effects and mechanism of HRS combined with vacuum sealing drainage (VSD) in a rabbit full-thickness wound model. Our results indicated that the combination treatment of HRS and VSD could accelerate wound healing. In vitro experiments further confirmed its effects on HaCaT keratinocytes. We found that 45 metabolites were significantly changed between the VSD + HRS group and the VSD + saline-treated group. Pathway enrichment analysis indicated that biotin metabolism was the potential target pathway. The biochemical interpretation analysis demonstrated that combining HRS and VSD might enhance mitochondrial function, ATP synthesis, and GSH homeostasis by altering biotin metabolism. The detection of representative indicators of oxidative stress supported the critical metabolic pathway analysis as well. In summary, VSD combined with HRS might provide a new strategy to enhance wound healing.
C1 [Kuang, Xinwen; Liang, Zhengyun; Xia, Yijun; Shan, Mengjie; Hao, Yan; Liu, Hao; Wang, Zhi; Feng, Cheng; Chang, Guojing; Wang, Youbin] Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Plast Surg, Beijing, Peoples R China.
   [Liang, Zhengyun] Shenzhen Inst Dermatol, Shenzhen Ctr Chron Dis Control, Dept Dermatol, Shenzhen, Peoples R China.
   [He, Qianjun; Xia, Chao] Shanghai Jiao Tong Univ, Shanghai Key Lab Hydrogen Sci, Shanghai, Peoples R China.
   [He, Qianjun; Xia, Chao] Shanghai Jiao Tong Univ, Ctr Hydrogen Sci, Sch Mat Sci & Engn, Shanghai, Peoples R China.
C3 Chinese Academy of Medical Sciences - Peking Union Medical College;
   Peking Union Medical College; Peking Union Medical College Hospital;
   Shanghai Jiao Tong University; Shanghai Jiao Tong University
RP Wang, YB (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Plast Surg, Beijing, Peoples R China.
EM wybenz@sina.com
RI He, Qianjun/M-2642-2013
OI Kuang, Xinwen/0000-0002-6876-7844
FU Clinical Research Special Fund of Peking Union Medical College Hospital,
   Peking Union Medical College;  [2022-PUMCH-B-040]
FX This research was funded by the Clinical Research Special Fund of Peking
   Union Medical College Hospital, Peking Union Medical College
   (2022-PUMCH-B-040). We thank Nanobubble Technology (Shanghai, China) for
   providing the hydrogen-rich water-generating electrolytic bottles.
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NR 60
TC 1
Z9 1
U1 1
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1582-1838
EI 1582-4934
J9 J CELL MOL MED
JI J. Cell. Mol. Med.
PD JAN 13
PY 2025
VL 29
IS 1
AR e70292
DI 10.1111/jcmm.70292
PG 14
WC Cell Biology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Research & Experimental Medicine
GA S0R8H
UT WOS:001395413000001
PM 39804806
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Tokusa, M
   Rikimaru, H
AF Tokusa, M.
   Rikimaru, H.
TI Negative pressure wound therapy for three outpatients
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Tokusa, M.; Rikimaru, H.] Souryu Kai Asahi Hosp, Kyoto, Japan.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD SEP
PY 2020
VL 28
IS 5
MA P-17
BP A11
EP A12
PG 2
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA NN7RN
UT WOS:000568983900036
DA 2026-07-24
ER

PT J
AU Armstrong, DG
AF Armstrong, David G.
TI Discussion: Update on Negative-Pressure Wound Therapy
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Editorial Material
C1 Univ Arizona, Tucson, AZ 85724 USA.
C3 University of Arizona
RP Armstrong, DG (通讯作者)，Univ Arizona, Tucson, AZ 85724 USA.
EM armstrong@usa.net
CR Armstrong DG, 2009, INT WOUND J, V6, P211, DOI 10.1111/j.1742-481X.2009.00598.x
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
NR 3
TC 4
Z9 5
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JAN
PY 2011
VL 127
IS 1
SU S
BP 116S
EP 116S
DI 10.1097/PRS.0b013e3181fb5431
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 705IP
UT WOS:000286122400017
PM 21200281
DA 2026-07-24
ER

PT J
AU Neiswender, LO
AF Neiswender, Linda O.
TI NEGATIVE PRESSURE WOUND THERAPY IN AN INFANT
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Neiswender, Linda O.] Primary Childrens Med Ctr, Salt Lake City, UT 84103 USA.
EM linda.neiswender@imail.org
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2009
VL 36
IS 3
BP S14
EP S14
DI 10.1097/01.WON.0000351922.68952.cf
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 446KH
UT WOS:000266120000037
DA 2026-07-24
ER

PT J
AU Lee, MJ
   Pinkney, TD
AF Lee, Matthew J.
   Pinkney, Thomas D.
TI Negative pressure wound therapy: does it suck?
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Editorial Material
C1 [Lee, Matthew J.; Pinkney, Thomas D.] Univ Birmingham, Coll Med & Hlth, Dept Appl Hlth Sci, Birmingham B15 2TT, England.
C3 University of Birmingham
RP Lee, MJ (通讯作者)，Univ Birmingham, Coll Med & Hlth, Dept Appl Hlth Sci, Birmingham B15 2TT, England.
EM m.j.lee.1@bham.ac.uk
RI Pinkney, Thomas/HGA-4022-2022; Lee, Matthew/I-3538-2019
OI Pinkney, Thomas/0000-0001-7320-6673; Lee, Matthew/0000-0001-9971-1635
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Arundel C., 2025, Lancet
   Atherton K, 2025, JAMA-J AM MED ASSOC, V333, P853, DOI 10.1001/jama.2024.24764
   Dumville JC, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011278.pub2
   Leaper DJ, 2017, J HOSP INFECT, V95, P135, DOI 10.1016/j.jhin.2016.12.016
   NICE, 2019, Medical Technologies Guidance (MTG43)
   NIHR, About us
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   Saramago P, 2025, BJS-BRIT J SURG, V112, DOI 10.1093/bjs/znaf077
NR 9
TC 1
Z9 1
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD MAY
PY 2025
VL 112
IS 5
AR znaf093
DI 10.1093/bjs/znaf093
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 2GH7T
UT WOS:001481970300001
PM 40326753
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Hughes, J
   Leavitt, T
AF Hughes, Janice
   Leavitt, Tracy
TI VENOUS ULCERS AND NEGATIVE PRESSURE WOUND THERAPY
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Hughes, Janice] Heritage Home Hlth Care, Murray, UT USA.
   [Leavitt, Tracy] Kci, Salt Lake City, UT USA.
EM jan@jtechcons.com; tracy.leavitt@kci1.com
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2012
VL 39
IS 3
SU S
MA 6129
BP S18
EP S18
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 948MP
UT WOS:000304507600048
DA 2026-07-24
ER

PT J
AU Sjögren, J
   Nilsson, J
   Gustafsson, R
   Malmsjö, M
   Ingemansson, R
AF Sjögren, J
   Nilsson, J
   Gustafsson, R
   Malmsjö, M
   Ingemansson, R
TI The impact of vacuum-assisted closure on long-term survival after
   post-sternotomy mediastinitis
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID STERNAL WOUND-INFECTION; RISK-FACTORS; EUROPEAN SYSTEM; MUSCLE FLAPS;
   COMPLICATIONS; THERAPY; MANAGEMENT; MORTALITY; SURGERY
AB Background. Post-sternotomy mediastinitis after coronary artery bypass grafting is reported to be a strong predictor for poor late survival when using conventional wound-healing therapies. The aim of this study was to compare the long-term survival after vacuum-assisted closure treated mediastinitis following coronary artery bypass grafting with that of patients without mediastinitis. Another objective was to identify risk factors for developing mediastinitis.
   Methods. Forty-six patients were treated for mediastinitis, with vacuum-assisted closure but without additional tissue flaps, after isolated coronary bypass grafting between January 1999 and September 2004. During this period, 4,781 patients underwent isolated coronary bypass grafting without mediastinitis. Actuarial survival was compared with the log-rank test. Univariate and multivariate analysis were used to identify risk factors for mediastinitis.
   Results. There was no difference in early or late survival between the mediastinitis group treated with vacuum-assisted closure and the control group (p = not significant). The survival at 1, 3, and 5 years was 92.9% +/- 4.0%, 89.2% +/- 5.2%, and 89.2% +/- 5.2%, respectively, in the vacuum-assisted closure group; and 96.5% +/- 0.3%, 92.1% +/- 0.5%, and 86.9% +/- 0.8%, respectively, in the control group. Diabetes mellitus, low left ventricular ejection fraction, obesity, renal failure, and three-vessel disease were identified as risk factors for developing mediastinitis.
   Conclusions. This study suggests that patients with vacuum-assisted closure treated mediastinitis may have similar long-term survival as patients without mediastinitis after coronary artery bypass grafting. The independent risk factors identified were similar to those found in previous studies. Our data support that vacuum-assisted closure therapy minimizes the negative effects of mediastinitis on late survival after coronary artery bypass grafting.
C1 Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Div, SE-22185 Lund, Sweden.
   Univ Lund Hosp, Dept Internal Med, SE-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital
RP Sjögren, J (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Div, SE-22185 Lund, Sweden.
EM johan.sjogren@thorax.lu.se
RI ; Sjögren, Johan/AAZ-6448-2021; Nilsson, Johan/A-4742-2011
OI Maljö, Malin/0000-0001-9849-9599; Ingemansson,
   Richard/0000-0001-7623-8953; Nilsson, Johan/0000-0001-6860-6090
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   Nilsson J, 2004, ANN THORAC SURG, V77, P1235, DOI 10.1016/j.athoracsur.2003.08.034
   Rand RP, 1998, ANN THORAC SURG, V65, P1046, DOI 10.1016/S0003-4975(98)00087-3
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   RINGELMAN PR, 1994, PLAST RECONSTR SURG, V93, P1208, DOI 10.1097/00006534-199405000-00015
   SARR MG, 1984, ANN THORAC SURG, V38, P415, DOI 10.1016/S0003-4975(10)62300-4
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   Toumpoulis IK, 2005, CHEST, V127, P464, DOI 10.1378/chest.127.2.464
   Toumpoulis IK, 2004, EUR J CARDIO-THORAC, V25, P51, DOI 10.1016/S1010-7940(03)00651-1
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Yuen JC, 1995, ANN PLAS SURG, V35, P585, DOI 10.1097/00000637-199512000-00005
NR 38
TC 88
Z9 96
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD OCT
PY 2005
VL 80
IS 4
BP 1270
EP 1275
DI 10.1016/j.athoracsur.2005.04.010
PG 6
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 972GK
UT WOS:000232442100017
PM 16181853
DA 2026-07-24
ER

PT J
AU McBride, CA
   Stockton, K
   Storey, K
   Kimble, RM
AF McBride, Craig A.
   Stockton, Kellie
   Storey, Kristen
   Kimble, Roy M.
TI Negative pressure wound therapy facilitates closure of large congenital
   abdominal wall defects
SO PEDIATRIC SURGERY INTERNATIONAL
LA English
DT Article
DE Negative pressure wound therapy; Abdominal wall defect; Hernia,
   abdominal; Gastroschisis; Pediatric; Repair
ID GIANT OMPHALOCELE
AB The degree of viscero-abdominal disproportion often makes single-stage reduction difficult in large abdominal wall defects, without risking respiratory or hemodynamic compromise. As a consequence, clinicians have adopted a number of different methods to control these defects. Repair may be in the neonatal period, or later in life. Delayed repairs require epithelialization of the gastroschisis or omphalocele. Definitive repair may be in single or multiple stages. This paper describes four children in whom negative pressure wound therapy (NPWT) was used to facilitate closure of these complex defects.
C1 [McBride, Craig A.; Stockton, Kellie; Storey, Kristen; Kimble, Roy M.] Univ Queensland, Queensland Childrens Med Res Inst, Ctr Childrens Burns & Trauma Res, Brisbane, Qld, Australia.
   [McBride, Craig A.; Stockton, Kellie; Storey, Kristen; Kimble, Roy M.] Childrens Hlth Queensland, Stuart Pegg Paediat Burns Ctr, Brisbane, Qld, Australia.
   [McBride, Craig A.] Univ Queensland, Royal Childrens Hosp, Dept Paediat & Child Hlth, Herston, Qld 4029, Australia.
C3 University of Queensland; Royal Children's Hospital Brisbane; University
   of Queensland
RP McBride, CA (通讯作者)，Univ Queensland, Queensland Childrens Med Res Inst, Ctr Childrens Burns & Trauma Res, Brisbane, Qld, Australia.
EM craig.a.mcbride@gmail.com
RI Stockton, Kellie/F-2423-2015; McBride, Craig/G-4805-2011; Kimble,
   Roy/B-4160-2011
OI Stockton, Kellie/0000-0002-0756-5157; McBride,
   Craig/0000-0001-8377-1748; Kimble, Roy/0000-0002-2449-7707
CR Adetayo OA, 2012, ANN PLAS SURG, V69, P104, DOI 10.1097/SAP.0b013e31822128f5
   Choi WW, 2011, PEDIATR SURG INT, V27, P907, DOI 10.1007/s00383-011-2868-6
   Davies MW, 2002, COCHRANE DB SYST REV, V3, DOI DOI 10.1002/14651858.CD003671
   Foroutan H, 2013, ANN COLORECTAL RES, V1, P32, DOI [10.5812/acr.11475, DOI 10.5812/ACR.11475]
   Kaabachi O, 1998, EUR J PEDIATR SURG, V8, P371, DOI 10.1055/s-2008-1071236
   Kilbride KE, 2006, J PEDIATR SURG, V41, P212, DOI 10.1016/j.jpedsurg.2005.10.003
   Leppäniemi A, 2013, SCAND J SURG, V102, P14, DOI 10.1177/145749691310200104
   Levy S, 2013, J PEDIATR SURG, V48, P2525, DOI 10.1016/j.jpedsurg.2013.05.067
   Morris MW, 2013, J PEDIATR SURG, V48, pE13, DOI 10.1016/j.jpedsurg.2013.03.005
   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
   Sakata S, 2009, PEDIATR SURG INT, V25, P117, DOI 10.1007/s00383-008-2289-3
   van Eijck FC, 2011, J PEDIATR SURG, V46, P482, DOI 10.1016/j.jpedsurg.2010.08.050
NR 12
TC 10
Z9 11
U1 0
U2 4
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0179-0358
EI 1437-9813
J9 PEDIATR SURG INT
JI Pediatr. Surg. Int.
PD NOV
PY 2014
VL 30
IS 11
BP 1163
EP 1168
DI 10.1007/s00383-014-3545-3
PG 6
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA AS5UX
UT WOS:000344335900013
PM 25060123
DA 2026-07-24
ER

PT J
AU Engel, R
   Greenberg, Y
   Siddiqui, A
AF Engel, Ricardo
   Greenberg, Yitzchok
   Siddiqui, Aamir
TI Negative Pressure Wound Therapy for Improved Nipple Survival in Large
   Volume Reduction Mammaplasty
SO AESTHETIC PLASTIC SURGERY
LA English
DT Article
DE Negative pressure wound therapy; npwt; Breast reduction; Mammaplasty;
   Macromastia; Gigantomastia; Nipple ischemia; Nipple necrosis
ID BREAST REDUCTION; GRAFT; COMPLICATIONS; SENSATION; SUPERIOR
AB Background Large volume breast reductions are at increased risk of nipple ischemia and necrosis due to tenuous blood supply of long pedicles. We adapted incisional negative pressure wound therapy to augment nipple survival in such patients undergoing mammaplasty by inferior pedicle technique.
   Methods Patients with nipple-to-inframammary fold distance > 14 cm were informed of increased risk of requiring free nipple graft. All patients underwent inferior pedicle technique with Wise pattern skin incision. Once incisions were closed and the nipple-areolar complex was inset, the complex was assessed for vascularity. In 12 cases there was evidence of compromised arterial inflow or venous outflow. For these patients, incisional negative pressure wound therapy was applied to the bilateral nipple-areolar complexes for 5-7 days.
   Results None of the 12 patients (24 breasts) in this series experienced nipple-areolar complex ischemia or necrosis. Only 2 patients experienced delayed wound healing which was successfully managed by local wound care.
   Conclusions This study demonstrates the utility of negative pressure wound therapy in nipple survival for at-risk patients. We believe it augments healing by allowing improved micro-circulation.
C1 [Engel, Ricardo] Wayne State Univ, Sch Med, 540 E Canfield, Detroit, MI 48201 USA.
   [Greenberg, Yitzchok; Siddiqui, Aamir] Henry Ford Hlth Syst, Detroit, MI USA.
C3 Wayne State University; Henry Ford Health System; Henry Ford Hospital
RP Engel, R (通讯作者)，Wayne State Univ, Sch Med, 540 E Canfield, Detroit, MI 48201 USA.
EM ricardo.engel@med.wayne.edu
RI siddiqui, aamir/B-1708-2009
OI Engel, Ricardo/0000-0002-7184-7714
CR Ahmed OA, 2000, BRIT J PLAST SURG, V53, P126, DOI 10.1054/bjps.1999.3235
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   Galiano RD, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001560
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   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Hudson DA, 2015, INT WOUND J, V12, P195, DOI 10.1111/iwj.12080
   Karacor-Altuntas Z, 2016, ANN PLAS SURG, V76, P383, DOI 10.1097/SAP.0000000000000388
   Karsidag S, 2011, AESTHET PLAST SURG, V35, P254, DOI 10.1007/s00266-010-9592-9
   Lo AY, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9063
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   Nelson JA, 2014, J PLAST SURG HAND SU, V48, P334, DOI 10.3109/2000656X.2014.886582
   Özerdem ÖR, 2002, ANN PLAS SURG, V49, P506, DOI 10.1097/01.SAP.0000015433.35151.D8
   ROMANO JJ, 1992, ANN PLAS SURG, V28, P271, DOI 10.1097/00000637-199203000-00012
   Stranz G, 1999, Zentralbl Gynakol, V121, P434
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   van Deventer PV, 2008, AESTHET PLAST SURG, V32, P307, DOI 10.1007/s00266-007-9070-1
   Yin YC, 2018, INT J SURG, V50, P43, DOI 10.1016/j.ijsu.2017.12.020
NR 23
TC 6
Z9 8
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0364-216X
EI 1432-5241
J9 AESTHET PLAST SURG
JI Aesthet. Plast. Surg.
PD FEB
PY 2022
VL 46
IS 1
BP 108
EP 112
DI 10.1007/s00266-021-02492-0
EA AUG 2021
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA YX3GN
UT WOS:000681528000003
PM 34355263
DA 2026-07-24
ER

PT J
AU Girard, P
   Plancq, MC
   Tourneux, P
   Deroussen, F
   Gouron, R
   Klein, C
AF Girard, P.
   Plancq, M. -C.
   Tourneux, P.
   Deroussen, F.
   Gouron, R.
   Klein, C.
TI Extravasation of calcium solution in the child: Value of
   negative-pressure wound therapy
SO ARCHIVES DE PEDIATRIE
LA English
DT Article
DE Extravasation; Calcium solutions; Negative-pressure wound therapy
ID MANAGEMENT; GLUCONATE; EFFICACY
AB The extravasation of a calcium solution into soft tissue constitutes a medical emergency, and a lack of adequate management can lead to significant functional and cosmetic sequelae. Here, we report on the management of and long-term outcome in two children who experienced calcium infusion leakage. We also describe the emergency procedures used in cases of extravasation and discuss the role of negative pressure wound therapy as an appropriate adjunct to conventional techniques for dealing with serious extravasation-related injuries. (C) 2019 French Society of Pediatrics. Published by Elsevier Masson SAS. All rights reserved.
C1 [Girard, P.; Plancq, M. -C.; Deroussen, F.; Gouron, R.; Klein, C.] CHU Amiens Picardie, Grp Hosp Sud, Serv Orthoped Pediat, F-80054 Amiens 1, France.
   [Tourneux, P.] Grp Hosp Sud, Pole Femme Couple Enfant Med Neonatale & Reanimat, F-80054 Amiens 1, France.
C3 Universite de Picardie Jules Verne (UPJV); CHU Amiens
RP Klein, C (通讯作者)，CHU Amiens Picardie, Grp Hosp Sud, Serv Orthoped Pediat, F-80054 Amiens 1, France.
EM celinekleinfr@yahoo.fr
RI Gouron, Richard/AGM-3039-2022; Tourneux, Pierre/AAX-3748-2021
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   Compaña FJP, 2017, ANN PLAS SURG, V79, P444, DOI 10.1097/SAP.0000000000001110
   Pasquesoone L, 2016, ANN CHIR PLAST ESTH, V61, P598, DOI 10.1016/j.anplas.2016.07.016
   Tofani BF, 2012, J PEDIATR NURS, V27, P682, DOI 10.1016/j.pedn.2012.01.005
   Xu C, 2016, ANZ J SURG, V86, P421, DOI 10.1111/ans.13437
NR 13
TC 6
Z9 8
U1 0
U2 6
PU ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
PI ISSY-LES-MOULINEAUX
PA 65 RUE CAMILLE DESMOULINS, CS50083, 92442 ISSY-LES-MOULINEAUX, FRANCE
SN 0929-693X
EI 1769-664X
J9 ARCH PEDIATRIE
JI Arch. Pediatr.
PD OCT
PY 2019
VL 26
IS 7
BP 407
EP 410
DI 10.1016/j.arcped.2019.09.011
PG 4
WC Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics
GA JR6WV
UT WOS:000499764100003
PM 31630900
OA Bronze
DA 2026-07-24
ER

PT J
AU Lee, J
   Lee, KJ
   Sun, WY
AF Lee, Jina
   Lee, Kwan Ju
   Sun, Woo Young
TI Necrotizing fasciitis of the breast in a pregnant woman successfully
   treated using negative-pressure wound therapy
SO ANNALS OF SURGICAL TREATMENT AND RESEARCH
LA English
DT Article
DE Necrotizing fasciitis; Breast; Pregnancy; Negative-pressure wound
   therapy
ID SOFT-TISSUE INFECTIONS
AB Necrotizing fasciitis (NF) is a rare and rapidly progressive disease involving the skin, subcutaneous tissue, and deep soft tissue. Although NF can occur any part of the body, the breast is an uncommon primary site for NF, and its occurrence in the breast during pregnancy has never previously been reported. Here, we report the case of a healthy 31-year-old pregnant woman who presented with NF of the left breast that was successfully treated with breast-conserving debridement and secondary wound closure using negative-pressure wound therapy.
C1 [Lee, Jina; Lee, Kwan Ju; Sun, Woo Young] Catholic Univ Korea, Coll Med, Daejeon St Marys Hosp, Dept Surg, Taejon 301723, South Korea.
C3 Catholic University of Korea
RP Sun, WY (通讯作者)，Catholic Univ Korea, Coll Med, Daejeon St Marys Hosp, Dept Surg, 64 Daeheung Ro, Taejon 301723, South Korea.
EM sun2729@naver.com
OI Sun, Woo Young/0000-0002-5447-4266
CR Angarita FA, 2014, BREAST CANCER-TOKYO, V21, P108, DOI 10.1007/s12282-010-0219-4
   Cho YS, 2010, J KOREAN SURG SOC, V79, P71, DOI 10.4174/jkss.2010.79.1.71
   Elliott D, 2000, AM J SURG, V179, P361, DOI 10.1016/S0002-9610(00)00360-3
   Flandrin A, 2009, BREAST J, V15, P199, DOI 10.1111/j.1524-4741.2009.00697.x
   Hanif MA, 2008, J CLIN ULTRASOUND, V36, P517, DOI 10.1002/jcu.20492
   Liao EC, 2007, ANN PLAS SURG, V59, P218, DOI 10.1097/SAP.0b013e31802c148c
   Salcido Richard Sal, 2007, Adv Skin Wound Care, V20, P288, DOI 10.1097/01.ASW.0000269317.76380.3b
   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
   Wong CH, 2004, CRIT CARE MED, V32, P1535, DOI 10.1097/01.CCM.0000129486.35458.7D
   Yen ZS, 2002, ACAD EMERG MED, V9, P1448, DOI 10.1111/j.1553-2712.2002.tb01619.x
NR 10
TC 18
Z9 22
U1 0
U2 7
PU KOREAN SURGICAL SOCIETY
PI SEOUL
PA 3304HO, 101 DONG, BROWNSTONE SEOUL, 335, JUNGMIN-DONG, JUNG-GU, SEOUL,
   100-859, SOUTH KOREA
SN 2288-6575
EI 2288-6796
J9 ANN SURG TREAT RES
JI Ann. Surg. Treat. Res.
PD AUG
PY 2015
VL 89
IS 2
BP 102
EP 106
DI 10.4174/astr.2015.89.2.102
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CO1ET
UT WOS:000358897300009
PM 26236701
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Benrashid, E
   Youngwirth, LM
   Guest, K
   Cox, MW
   Shortell, CK
   Dillavou, ED
AF Benrashid, Ehsan
   Youngwirth, Linda M.
   Guest, Kimberly
   Cox, Mitchell W.
   Shortell, Cynthia K.
   Dillavou, Ellen D.
TI Negative Pressure Wound Therapy Reduces Surgical Site Infections
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Meeting Abstract
CT 32nd Annual Meeting of the Eastern-Vascular-Society (EVS)
CY SEP 06-08, 2018
CL Washington, DC
SP Eastern Vasc Soc
C1 [Benrashid, Ehsan; Youngwirth, Linda M.; Guest, Kimberly; Cox, Mitchell W.; Shortell, Cynthia K.; Dillavou, Ellen D.] Duke Univ, Durham, NC USA.
C3 Duke University
RI Cox, Mitchell/AHD-6296-2022
NR 0
TC 0
Z9 0
U1 0
U2 1
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
J9 J VASC SURG
JI J. Vasc. Surg.
PD AUG
PY 2018
VL 68
IS 2
BP E14
EP E15
DI 10.1016/j.jvs.2018.05.056
PG 4
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery; Cardiovascular System & Cardiology
GA GN7KU
UT WOS:000439318700027
DA 2026-07-24
ER

PT J
AU Climent, MT
   Coll, CM
   Cardona, MDM
   Orpinell, MB
   Montané, JR
   Farnós, MJP
   Sebastià, JP
AF Climent, M. T.
   Molinet Coll, C.
   Marti Cardona, M. D.
   Barahona Orpinell, M.
   Rovira Montane, J.
   Pla Farnos, M. J.
   Ponce Sebastia, J.
TI INCISIONAL NEGATIVE PRESSURE WOUND THERAPY IN ONCOLOGICAL PATIENTS
SO INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
LA English
DT Meeting Abstract
C1 [Climent, M. T.; Marti Cardona, M. D.; Barahona Orpinell, M.; Rovira Montane, J.; Pla Farnos, M. J.; Ponce Sebastia, J.] Bellvitge Univ Hosp, Gynecol, Barcelona, Spain.
   [Molinet Coll, C.] Hosp St Joan de Deu, Gynecol, Barcelona, Spain.
C3 Institut d'Investigacio Biomedica de Bellvitge (IDIBELL); Bellvitge
   University Hospital; University of Barcelona; University of Barcelona
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1048-891X
EI 1525-1438
J9 INT J GYNECOL CANCER
JI Int. J. Gynecol. Cancer
PD NOV
PY 2017
VL 27
SU 4
MA ESGO7-1284
BP 1317
EP 1317
PG 1
WC Oncology; Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Obstetrics & Gynecology
GA FT6AO
UT WOS:000423235204012
DA 2026-07-24
ER

PT J
AU Gupta, S
   Cho, T
AF Gupta, S
   Cho, T
TI A literature review of negative pressure wound therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
RI Gupta, Subhas/C-5458-2018
OI Gupta, Subhas/0000-0001-5091-3922
NR 0
TC 4
Z9 9
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD NOV
PY 2004
SU A
BP 2S
EP 4S
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 875YA
UT WOS:000225457800002
DA 2026-07-24
ER

PT J
AU Buzhardt, S
   Chapple, AG
   LeMoine, F
   McCune, K
   Sutton, EF
AF Buzhardt, Sarah
   Chapple, Andrew G.
   LeMoine, Felicia
   McCune, Kelly
   Sutton, Elizabeth F.
TI Surgical site infection risk in cesarean delivery patients with obesity
   after negative pressure wound therapy: A retrospective cohort study
SO SURGERY
LA English
DT Article
ID COMPLICATIONS; WOMEN; POPULATION; PREVENTION; PREGNANCY; OUTCOMES;
   SECTION; SYSTEM; TRIAL
AB Background: There are conflicting reports of postoperative efficacy of negative pressure wound therapy in patients with obesity after cesarean delivery. Methods: Retrospective cohort study for patients with obesity and negative pressure wound therapy or abdominal dressing after cesarean delivery between April 1, 2014 and January 31, 2018. Postoperative surgical site infection was defined from medical record charting or positive wound culture and confirmed by the hospital's Infection Prevention team. Multivariable logistic regression model for surgical site infection was conducted including additional potential confounding variables. Mantel-Haenszel tests were conducted to stratify by body mass index class and operative time, and we performed quasi-Poisson regression to determine which factors were associated with an increased operative time. Results: We included 4,391 Black or White patients with obesity, 696 (15.9%) underwent negative pressure wound therapy and 3,695 (84.1%) abdominal dressing after cesarean delivery. Incidence of surgical site infection after negative pressure wound therapy and abdominal dressing were 6.1% and 3.4%, respectively (2-sample test of proportions P < .001). The multivariable logistic regression (covariates: race, diabetes, body mass index category, insurance, scheduled/emergency, artificial rupture, previous c-section, operative time, age, closure type) found negative pressure wound therapy dressing was associated with an increased risk of surgical site infection (adjusted odds ratio 1.54; 95% confidence interval, 1.01-2.34), as did a Mantel-Haenszel test which was stratified by body mass index (odds ratio 1.62; 95% confidence interval, 1.08-2.43) and a Mantel-Haenszel test stratified by operative time (odds ratio 1.85; 95% confidence interval, 1.28-2.65). Negative pressure wound therapy dressing also led to an increase in operative time in the Quasi-Poisson regression, which was the primary predictor of infection. Conclusion: Negative pressure wound therapy was associated with an increased the risk of postoperative surgical site infection after cesarean delivery in our obstetric patients with obesity. Future prospective studies are needed to determine a dressing type and other intervention to decrease postoperative cesarean surgical site infection in women with obesity. (c) 2021 Elsevier Inc. All rights reserved.
C1 [Buzhardt, Sarah; LeMoine, Felicia; McCune, Kelly] Louisiana State Univ, Dept Obstet & Gynecol, Hlth Sci Ctr, Baton Rouge, LA 70803 USA.
   [Chapple, Andrew G.] Louisiana State Univ, Sch Publ Hlth, Biostat Program, Hlth Sci Ctr, New Orleans, LA 70803 USA.
   [Sutton, Elizabeth F.] Womans Hosp, Womans Hosp Res Ctr, 100 Womans Way, Baton Rouge, LA 70817 USA.
C3 Louisiana State University System; Louisiana State University Health
   Sciences Center at Shreveport; Louisiana State University; Louisiana
   State University System; Louisiana State University Health Sciences
   Center New Orleans
RP Sutton, EF (通讯作者)，Womans Hosp, Womans Hosp Res Ctr, 100 Womans Way, Baton Rouge, LA 70817 USA.
EM Elizabeth.Sutton@womans.org
FU Louisiana State University Health Sciences Center; Obstetrics and
   Gynecology Residency Research Program; Woman's Hospital Research Center
   of Woman's Hospital, Baton Rouge, Louisiana
FX This research study was supported generously by donated time and effort
   by the Louisiana State University Health Sciences Center, Obstetrics and
   Gynecology Residency Research Program and Woman's Hospital Research
   Center of Woman's Hospital, Baton Rouge, Louisiana.
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   Yang ZJ, 2019, AUST NZ J OBSTET GYN, V59, P367, DOI 10.1111/ajo.12866
NR 31
TC 3
Z9 5
U1 0
U2 7
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
EI 1532-7361
J9 SURGERY
JI Surgery
PD JUL
PY 2021
VL 170
IS 1
BP 153
EP 159
DI 10.1016/j.surg.2021.02.056
EA JUN 2021
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA TA5OR
UT WOS:000667298800025
PM 33838882
DA 2026-07-24
ER

PT J
AU Close, M
AF Close, Malinda
TI NEGATIVE-PRESSURE WOUND THERAPY ON MUCOCUTANEOUS JUNCTION SEPARATION
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Close, Malinda] Wound Ost, Salem, OR USA.
EM Malinda.Close@salemhealth.org
CR Aboulian A, 2019, CLIN COLON RECT SURG, V32, P314, DOI 10.1055/s-0039-1683924
   El-Sabbagh AH, 2017, CHIN J TRAUMATOL, V20, P103, DOI 10.1016/j.cjtee.2016.09.004
   Murken DR, 2019, CLIN COLON RECT SURG, V32, P176, DOI 10.1055/s-0038-1676995
   Tsujinaka S, 2020, J ANUS RECTUM COLON, V4, P25, DOI 10.23922/jarc.2019-032
   Wirth U, 2018, INT WOUND J, V15, P722, DOI 10.1111/iwj.12916
NR 5
TC 0
Z9 0
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2023
VL 50
IS 3
SU S
MA PI71
BP S49
EP S50
PG 2
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA S6IO9
UT WOS:001072181900109
DA 2026-07-24
ER

PT J
AU Rhee, P
   Velmahos, GC
AF Rhee, P
   Velmahos, GC
TI Traumatic wounds
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; OPEN ABDOMENS
C1 Univ So Calif, Keck Sch Med, Los Angeles, CA 90089 USA.
   Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
   USN, Trauma Training Ctr, Los Angeles, CA USA.
C3 University of Southern California; Uniformed Services University of the
   Health Sciences - USA; United States Department of Defense; United
   States Navy
RP Rhee, P (通讯作者)，Univ So Calif, Keck Sch Med, Los Angeles, CA 90089 USA.
EM prhee@nshs-sd.med.navy.mil
RI Rhee, Peter/GPP-0883-2022
CR Alvarez AA, 2001, GYNECOL ONCOL, V80, P413, DOI 10.1006/gyno.2000.6092
   Büttgenbach S, 2001, MICROSYST TECHNOL, V7, P165, DOI 10.1007/s005420000082
   Demaria R, 2001, J Wound Care, V10, P12
   Elwood ET, 2001, ANN PLAS SURG, V46, P49, DOI 10.1097/00000637-200101000-00010
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   Greer SE, 2000, BRIT J PLAST SURG, V53, P484, DOI 10.1054/bjps.2000.3360
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   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Yuan-Innes M. J., 2001, Spine, V26, pE1
NR 9
TC 0
Z9 0
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2004
SU S
BP 22
EP 25
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 817VB
UT WOS:000221203900008
PM 15317241
DA 2026-07-24
ER

PT J
AU de Leon, J
AF de Leon, J
TI Negative pressure wound therapy in pressure ulcer management
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article; Proceedings Paper
CT National Vacuum-Assisted Closure Education Conference
CY NOV 05-07, 2004
CL Los Angeles, CA
CR *AHCPR, 1992, CLIN GUID, V3
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NR 10
TC 2
Z9 7
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD FEB
PY 2005
SU S
BP 3S
EP 8S
PG 6
WC Dermatology; Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 906AP
UT WOS:000227613200002
DA 2026-07-24
ER

PT J
AU Gijón, MM
   Sánchez, AS
   Alvarez, ID
   Miravalles, JLR
   Pais, SA
   Uría, RR
   Navarro, SS
   Vico, TD
   Santos, ET
   Alvarez, LS
AF Gijon, Maria Moreno
   Sanchez, Aida Suarez
   Alvarez, Irene de Santiago
   Miravalles, Jose Luis Rodicio
   Pais, Sonia Amoza
   Uria, Raquel Rodriguez
   Navarro, Sandra Sanz
   Vico, Tamara Diaz
   Santos, Estrella Turienzo
   Alvarez, Lourdes Sanz
TI The efficacy of negative-pressure wound therapy (NPWT) in the prevention
   of surgical site occurrences in open abdominal surgery: A randomized
   clinical trial
SO SURGERY
LA English
DT Article
ID CARE-ASSOCIATED INFECTIONS; METAANALYSIS; COSTS
AB Background: The secondary consequences of surgical site occurrences, especially surgical site infections, worsen the patient's outcomes while significantly increasing health care costs. The implementation of preventive measures to reduce this complication rate should be one of the priorities to improve health care. Methods: A randomized, open-label clinical trial was conducted between March 2019 and March 2021 in a general surgery department. Individuals who had undergone laparotomy and had risk factors for developing surgical site infections and surgical site occurrences were included and randomized to use either negative-pressure wound therapy or conventional dressing (control group) on the closed surgical incision. The aim of our study was to evaluate the benefit of negative-pressure wound therapy in the surgical site infection rates and other surgical site occurrences in both groups at a 30-day follow-up. Results: Two hundred seventy-five participants were recruited and were analyzed, 147 (53.5%) in the negative-pressure wound therapy group and 128 (46.5%) in the control group. Thirty-one (11.3%) surgical site infections and 71 (25.8%) other surgical site occurrences were observed, being significantly lower in the negative-pressure wound therapy group (odds ratio 0.31, 95% confidence interval 0.14-0.71; P = .005) and (odds ratio 0.51, 95% confidence interval 0.29-0.90; P = .02), respectively. Absolute risk reduction was 13% for surgical site infection and 12% for other surgical site occurrences. Number needed to treat 9 (95% confidence interval 5-29) for surgical site infection and number needed to treat of 8 (95% confidence interval 5-51) for other surgical site occurrences. Median hospital stay was 3 days lower in the negative-pressure wound therapy group than in the control group (9 vs 12 days; P = .03). No severe adverse events attributable to the negative-pressure wound therapy dressing were reported. Conclusion: Negative-pressure wound therapy decreases the risk of surgical site occurrences and surgical site infection after laparotomy, so that its use should be considered in patients with risk factors. (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
C1 [Gijon, Maria Moreno; Sanchez, Aida Suarez; Miravalles, Jose Luis Rodicio; Pais, Sonia Amoza; Uria, Raquel Rodriguez; Navarro, Sandra Sanz; Santos, Estrella Turienzo; Alvarez, Lourdes Sanz] Asturias Cent Univ Hosp HUCA, Gen Surg Dept, Oviedo, Spain.
   [Gijon, Maria Moreno; Sanchez, Aida Suarez; Miravalles, Jose Luis Rodicio; Pais, Sonia Amoza; Uria, Raquel Rodriguez; Navarro, Sandra Sanz; Santos, Estrella Turienzo; Alvarez, Lourdes Sanz] Hlth Res Inst Principal Asturias ISPA, Oviedo, Spain.
   [Alvarez, Irene de Santiago] San Agustin Hosp, Gen Surg Dept, Aviles, Spain.
   [Vico, Tamara Diaz] Rey Juan Carlos Univ Hosp, Gen Surg Dept, Madrid, Spain.
C3 Central University Hospital Asturias; Instituto de Investigacion
   Sanitaria del Principado de Asturias (ISPA)
RP Gijón, MM (通讯作者)，Hosp Univ Cent Asturias HUCA, Gen Surg Dept, Ave Roma S-N, Oviedo, Asturias, Spain.
EM mmorensue@gmail.com
RI ; Díaz Vico, Tamara/AAU-4374-2021
OI Moreno Gijón, María/0000-0003-2328-9874; Rodicio Miravalles, Jose
   Luis/0000-0002-3223-6128; Díaz Vico, Tamara/0000-0002-4084-0501
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   Bueno-Lledó J, 2023, SURGERY, V173, P1052, DOI 10.1016/j.surg.2022.11.033
   Bueno-Lledó J, 2021, ANN SURG, V273, P1081, DOI 10.1097/SLA.0000000000004310
   CDC Ncezid DHQP, 2022, Surgical site infection event (SSI)
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   European Centre for Disease Prevention and Control, 2019, ECDC ANN EP REP 2017
   Gong SY, 2021, EXPERT REV GASTROENT, V15, P1309, DOI 10.1080/17474124.2021.1967143
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   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Pellino G, 2015, UPDATES SURG, V67, P235, DOI 10.1007/s13304-015-0298-z
   Petrosyan Y, 2021, ANN SURG, V273, P917, DOI 10.1097/SLA.0000000000003285
   Poehnert D, 2017, WOUND REPAIR REGEN, V25, P994, DOI 10.1111/wrr.12606
   Sahebally SM, 2018, JAMA SURG, V153, DOI 10.1001/jamasurg.2018.3467
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Schurtz E, 2018, AM J SURG, V215, P113, DOI 10.1016/j.amjsurg.2017.08.009
   Semsarzadeh NN, 2015, PLAST RECONSTR SURG, V136, P592, DOI 10.1097/PRS.0000000000001519
   Sorour AA, 2022, WOUNDS, V34, pE22, DOI 10.25270/wnds/2022.e22e28
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Tomsic I, 2020, BMC HEALTH SERV RES, V20, DOI 10.1186/s12913-020-4995-z
   Umscheid CA, 2011, INFECT CONT HOSP EP, V32, P101, DOI 10.1086/657912
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Young PY, 2014, SURG CLIN N AM, V94, P1245, DOI 10.1016/j.suc.2014.08.008
   Zimlichman E, 2013, JAMA INTERN MED, V173, P2039, DOI 10.1001/jamainternmed.2013.9763
NR 39
TC 6
Z9 7
U1 1
U2 6
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
J9 SURGERY
JI Surgery
PD FEB
PY 2025
VL 178
AR 108920
DI 10.1016/j.surg.2024.10.011
EA JAN 2025
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA T7Z0T
UT WOS:001407128700001
PM 39613656
DA 2026-07-24
ER

PT J
AU Gustafsson, R
   Sjögren, J
AF Gustafsson, R
   Sjögren, J
TI Untitled
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Letter
ID VACUUM-ASSISTED CLOSURE; BLOOD-FLOW; THERAPY
C1 Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital
RP Gustafsson, R (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden.
RI Sjögren, Johan/AAZ-6448-2021
CR Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Trabold O, 2003, WOUND REPAIR REGEN, V11, P504, DOI 10.1046/j.1524-475X.2003.11621.x
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
NR 4
TC 0
Z9 0
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2006
VL 18
IS 4
BP A16
EP A16
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 041HM
UT WOS:000237445300003
DA 2026-07-24
ER

PT J
AU Costa, ML
AF Costa, Matthew L.
TI Negative Pressure Wound Therapy for Open Fractures Reply
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Letter
C1 [Costa, Matthew L.] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford, England.
C3 University of Oxford
RP Costa, ML (通讯作者)，Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford Trauma, Oxford OX3 9DU, England.
EM matthew.costa@ndorms.ox.ac.uk
OI Costa, Matthew/0000-0003-3644-1388
FU UK National Institute for Health Research Health Technology Assessment
FX The author has completed and submitted the ICMJE Form for Disclosure of
   Potential Conflicts of Interest and reported receiving a grant from and
   being a member of the board of the UK National Institute for Health
   Research Health Technology Assessment.
CR Costa ML, 2018, JAMA-J AM MED ASSOC, V319, P2280, DOI 10.1001/jama.2018.6452
NR 1
TC 1
Z9 2
U1 0
U2 1
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD OCT 23
PY 2018
VL 320
IS 16
BP 1709
EP 1710
DI 10.1001/jama.2018.11751
PG 3
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GX8UQ
UT WOS:000448069100025
PM 30357290
DA 2026-07-24
ER

PT J
AU Heeney, A
   Mulsow, J
   O'Connell, PR
AF Heeney, Anna
   Mulsow, Jurgen
   O'Connell, P. Ronan
TI Vacuum-assisted closure of chronic anorectal fistula
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Letter
C1 [Heeney, Anna; Mulsow, Jurgen; O'Connell, P. Ronan] St Vincents Univ Hosp, Dept Surg, Dublin 4, Ireland.
C3 University College Dublin; Saint Vincent's University Hospital
RP O'Connell, PR (通讯作者)，St Vincents Univ Hosp, Dept Surg, Elm Pk, Dublin 4, Ireland.
EM ronan.oconnell@ucd.ie
RI O'Connell, P. Ronan/H-6583-2019
OI O'Connell, P. Ronan/0000-0002-1846-5629
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
NR 1
TC 1
Z9 1
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0179-1958
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD AUG
PY 2010
VL 25
IS 8
BP 1029
EP 1030
DI 10.1007/s00384-010-0909-6
PG 2
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 614UD
UT WOS:000279084400018
PM 20195619
DA 2026-07-24
ER

PT J
AU Bar-Meir, E
   Tamir, J
   Winkler, E
AF Bar-Meir, E
   Tamir, J
   Winkler, E
TI "Maya technique" for vacuum-assisted closure sealing
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Letter
C1 Chaim Sheba Med Ctr, Dept Plast & Reconstruct Surg, IL-52621 Tel Hashomer, Israel.
C3 Tel Aviv University; Chaim Sheba Medical Center
RP Bar-Meir, E (通讯作者)，St Hailanot 16, IL-49925 Kfar Mass, Israel.
EM eranbarmeir@yahoo.com
RI Tamir, Jonathan/KMY-3289-2024
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD SEP 1
PY 2005
VL 116
IS 3
BP 931
EP 931
DI 10.1097/01.prs.0000181257.24928.aa
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 961PY
UT WOS:000231675500046
PM 16141852
DA 2026-07-24
ER

PT J
AU Orgill, DP
   Zurovcik, DR
   Mody, GN
AF Orgill, Dennis P.
   Zurovcik, Danielle R.
   Mody, Gita N.
TI Reply: Alternative Materials in Vacuum-Assisted Closure
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Letter
C1 [Orgill, Dennis P.] Harvard Univ, Div Plast Surg, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USA.
   [Zurovcik, Danielle R.] MIT, Cambridge, MA 02139 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard Medical School; Massachusetts Institute of
   Technology (MIT)
RP Orgill, DP (通讯作者)，Harvard Univ, Div Plast Surg, Brigham & Womens Hosp, Sch Med, 75 Francis St, Boston, MA 02115 USA.
EM dorgill@partners.org
RI Mody, Gita/KQV-0468-2024; Orgill, Dennis/H-7596-2019
OI Mody, Gita/0000-0003-0218-6948; 
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1997, ANN PLAST SURG, V38, P577
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   U.S. Food and Drug administration, FDA SAF COMM UPDATE
NR 4
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD DEC
PY 2011
VL 128
IS 6
BP 785E
EP 786E
DI 10.1097/PRS.0b013e318230be8a
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 852DU
UT WOS:000297329700039
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI NEW DATA SUPPORT CONVATEC NEGATIVE PRESSURE WOUND THERAPY
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT News Item
NR 0
TC 0
Z9 0
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD SEP
PY 2009
VL 21
IS 9
BP A20
EP A20
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 507GB
UT WOS:000270839000008
DA 2026-07-24
ER

PT J
AU Gupta, S
   Cho, T
AF Gupta, S
   Cho, T
TI A literature review of negative pressure wound therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
C1 Loma Linda Univ, Med Ctr, Div Plast & Reconstruct Surg, Loma Linda, CA 92350 USA.
C3 Loma Linda University
RP Gupta, S (通讯作者)，Loma Linda Univ, Med Ctr, Div Plast & Reconstruct Surg, Loma Linda, CA 92350 USA.
EM sgupta@ahs.llumc.edu
RI Gupta, Subhas/C-5458-2018
OI Gupta, Subhas/0000-0001-5091-3922
NR 0
TC 0
Z9 1
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2004
SU S
BP 6
EP 8
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 817VB
UT WOS:000221203900003
PM 15317236
DA 2026-07-24
ER

PT J
AU Karabacak, E
   Mutluoglu, M
   Memis, A
   Ay, H
AF Karabacak, Ercan
   Mutluoglu, Mesut
   Memis, Ali
   Ay, Hakan
TI Unexpected wound occurring following negative pressure wound therapy
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Letter
C1 [Karabacak, Ercan] GATA Haydarpasa Teaching Hosp, Dept Dermatol, Istanbul, Turkey.
   [Mutluoglu, Mesut; Memis, Ali; Ay, Hakan] GATA Haydarpasa Teaching Hosp, Dept Underwater & Hyperbar Med, Istanbul, Turkey.
C3 Istanbul Haydarpasa Sultan Abdulhamid Training & Research Hospital;
   Gulhane Training & Research Hospital; Gulhane Training & Research
   Hospital; Istanbul Haydarpasa Sultan Abdulhamid Training & Research
   Hospital
RP Mutluoglu, M (通讯作者)，GATA Haydarpasa Teaching Hosp, Dept Underwater & Hyperbar Med, Istanbul, Turkey.
EM drmutluoglu@gmail.com
RI Mutluoglu, Mesut/B-4451-2009
OI Mutluoglu, Mesut/0000-0002-1112-5779
CR Mutluoglu M, 2013, J BURN CARE RES, V34, pE309, DOI 10.1097/BCR.0b013e3182777919
NR 1
TC 7
Z9 7
U1 0
U2 5
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2016
VL 13
IS 2
BP 289
EP 290
DI 10.1111/iwj.12232
PG 2
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA DH2UF
UT WOS:000372641400023
PM 24698303
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Ewart, E
   Wilson, J
   Kaur, G
AF Ewart, E.
   Wilson, J.
   Kaur, G.
TI LONG TERM RESULTS OF NEGATIVE PRESSURE WOUND THERAPY
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Ewart, E.; Wilson, J.; Kaur, G.] Scunthorpe Gen Hosp, Scunthorpe, England.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1067-1927
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV-DEC
PY 2010
VL 18
IS 6
MA 019
BP A81
EP A81
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 677KJ
UT WOS:000283991000020
DA 2026-07-24
ER

PT J
AU Papes, D
AF Papes, Dino
TI Negative Pressure Wound Therapy for Open Fractures
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Letter
ID CLASSIFICATION
C1 [Papes, Dino] Univ Hosp Ctr Zagreb, Dept Surg, Kispaticeva 12, Zagreb 10000, Croatia.
C3 University of Zagreb
RP Papes, D (通讯作者)，Univ Hosp Ctr Zagreb, Dept Surg, Kispaticeva 12, Zagreb 10000, Croatia.
EM dino.papes@kbc-zagreb.hr
CR [Anonymous], 2018, JAMA-J AM MED ASSOC, V319, P2280
   BRUMBACK RJ, 1994, J BONE JOINT SURG AM, V76A, P1162, DOI 10.2106/00004623-199408000-00006
   Durrant CAT, 2011, ANN PLAS SURG, V66, P9, DOI 10.1097/SAP.0b013e3181f88ecf
   HORN BD, 1993, J ORTHOP TRAUMA, V7, P357, DOI 10.1097/00005131-199308000-00012
NR 4
TC 3
Z9 5
U1 0
U2 3
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD OCT 23
PY 2018
VL 320
IS 16
BP 1709
EP 1709
DI 10.1001/jama.2018.11747
PG 1
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GX8UQ
UT WOS:000448069100024
PM 30357287
DA 2026-07-24
ER

PT J
AU Climent, MT
   Coll, CM
   Cardona, MDM
   Orpinell, MB
   Montané, JR
   Farnós, MJP
   Sebastià, JP
AF Climent, M. T.
   Molinet Coll, C.
   Marti Cardona, M. D.
   Barahona Orpinell, M.
   Rovira Montane, J.
   Pla Farnos, M. J.
   Ponce Sebastia, J.
TI INCISIONAL NEGATIVE PRESSURE WOUND THERAPY IN ONCOLOGICAL PATIENTS
SO INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
LA English
DT Meeting Abstract
C1 [Climent, M. T.; Marti Cardona, M. D.; Barahona Orpinell, M.; Rovira Montane, J.; Pla Farnos, M. J.; Ponce Sebastia, J.] Bellvitge Univ Hosp, Gynecol, Barcelona, Spain.
   [Molinet Coll, C.] Hosp St Joan Deu, Gynecol, Barcelona, Spain.
C3 Institut d'Investigacio Biomedica de Bellvitge (IDIBELL); Bellvitge
   University Hospital; University of Barcelona; University of Barcelona
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1048-891X
EI 1525-1438
J9 INT J GYNECOL CANCER
JI Int. J. Gynecol. Cancer
PD NOV
PY 2017
VL 27
SU 4
MA ESGO7-1284
BP 241
EP 241
PG 1
WC Oncology; Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Obstetrics & Gynecology
GA FT6AO
UT WOS:000423235201231
DA 2026-07-24
ER

PT J
AU Rowan, M
   Niece, K
   Chung, K
   Akers, K
AF Rowan, Matthew
   Niece, Krista
   Chung, Kevin
   Akers, Kevin
TI ANTIBIOTIC WOUND PENETRANCE DURING NEGATIVE PRESSURE WOUND THERAPY
SO CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
CT 45th Critical Care Congress of the Society-of-Critical-Care-Medicine
CY FEB 20-24, 2016
CL Orlando, FL
SP Soc Crit Care Med
RI Rowan, Matthew/LIC-3246-2024
NR 0
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0090-3493
EI 1530-0293
J9 CRIT CARE MED
JI Crit. Care Med.
PD DEC
PY 2015
VL 43
IS 12
SU 1
MA 641
PG 1
WC Critical Care Medicine
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC General & Internal Medicine
GA DK2XT
UT WOS:000374778400642
DA 2026-07-24
ER

PT J
AU Schaum, KD
AF Schaum, KD
TI Negative pressure wound therapy pumps and ostomy supplies
SO OSTOMY WOUND MANAGEMENT
LA English
DT Editorial Material
C1 Kathleen D Schaum & Associates Inc, Lake Worth, FL USA.
C3 Kathleen D. Schaum & Associates
RP Schaum, KD (通讯作者)，Kathleen D Schaum & Associates Inc, Lake Worth, FL USA.
EM kathleendschaum@bellsouth.net
NR 0
TC 0
Z9 0
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD MAR
PY 2005
VL 51
IS 3
BP 20
EP +
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 000QS
UT WOS:000234477900003
PM 15984396
DA 2026-07-24
ER

PT J
AU Wu, YJ
   Chen, L
   Mao, XL
   Ru, ZL
   Yu, LY
   Chen, MM
   Wang, JN
   Chen, JJ
   Pang, QJ
AF Wu, Yaojun
   Chen, Liang
   Mao, Xinliang
   Ru, Zhengliang
   Yu, Liying
   Chen, Mimi
   Wang, Jingnan
   Chen, Jiejie
   Pang, Qingjiang
TI Closure of Complex Wounds by a Simple Skin Stretching System Associated
   With Vacuum Sealing Drainage-Clinical Outcome of 34 Patients
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE complex wounds; a simple skin stretching system; vacuum sealing drainage
ID ASSISTED CLOSURE; FASCIOTOMY; THERAPY; SECURE
AB Management of complex wounds with large skin defects presents a real challenge for orthopedic or reconstructive surgeons. We developed a simple skin stretching system associated with vacuum sealing drainage to examine the efficiency and complication. A total of 34 patients with different types of complex wounds were retrospectively included from January 2015 to March 2021. All patients in the study were underwent the treatment by 2 stages. The method was used to the wounds from 4.71 to 169.65 cm(2) with a median defect size of 25.13 cm(2). The median time for wound closure was 11.5 days (range: 5-32 days), although the median absolute reduction was 2.08 cm(2)/day (range: 0.15-25.66 cm(2)/day). Depending on the site of the wounds, the cause of the wound, and the rate of max-width/max-length (W/L), these complex wounds could be separately divided into several groups. There were statistically significant differences in the median value of the above variables (P < .05 Kruskal-Wallis test). The results showed that different anatomical sites had different viscoelastic properties, the complex wounds caused by trauma were easier to close than caused by diabetic foot and the complex wounds in group A (W/L > 0.5) were more difficult to close than in group B (W/L <= 0.5). No major complications were encountered in this study. In summary, the results of our study showed that the simple skin stretching system associated with vacuum sealing drainage was a safe approach for closure of complex wounds. Nevertheless, more attention should be paid to the viscoelasticity of the wounds to ensure closure and avoid undue complications when applying the method.
C1 [Wu, Yaojun; Chen, Liang; Mao, Xinliang; Yu, Liying; Chen, Mimi; Wang, Jingnan; Chen, Jiejie; Pang, Qingjiang] Univ Chinese Acad Sci, Hwa Mei Hosp, Ningbo, Peoples R China.
   [Wu, Yaojun; Chen, Liang; Mao, Xinliang; Yu, Liying; Chen, Mimi; Wang, Jingnan; Chen, Jiejie; Pang, Qingjiang] Univ Chinese Acad Sci, Ningbo Inst Life & Hlth Ind, Ningbo, Peoples R China.
   [Ru, Zhengliang] Cixi Third Peoples Hosp, Ningbo, Peoples R China.
C3 Chinese Academy of Sciences; University of Chinese Academy of Sciences,
   CAS; Chinese Academy of Sciences; University of Chinese Academy of
   Sciences, CAS
RP Chen, L (通讯作者)，Univ Chinese Acad Sci, Hwa Mei Hosp, Dept Orthoped, Ningbo Hosp2, Ningbo, Zhejiang, Peoples R China.
EM alanchen1@aliyun.com
FU Medical Scientific Research Foundation of Zhejiang Province, China
   [2020KY843, 2015KYB342]; Key Program of Ningbo Natural Science
   Foundation, China [2016A610146]; HwaMei Reasearch Foundation of Ningbo
   No. 2 Hospital, China [2019HMKY10]
FX This work was supported by supported by Medical Scientific Research
   Foundation of Zhejiang Province, China (Grant No. 2020KY843,
   2015KYB342); the Key Program of Ningbo Natural Science Foundation, China
   (Grant No. 2016A610146); HwaMei Reasearch Foundation of Ningbo No. 2
   Hospital, China (Grant No. 2019HMKY10).
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NR 33
TC 2
Z9 2
U1 0
U2 5
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD SEP
PY 2023
VL 22
IS 3
BP 555
EP 562
AR 15347346211032046
DI 10.1177/15347346211032046
EA JUL 2021
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA O1KU3
UT WOS:000678003300001
PM 34279133
DA 2026-07-24
ER

PT J
AU Helm, DL
   Dastouri, P
   Scherer, S
   Pietramaggiori, G
   Orgill, DP
AF Helm, Douglas L.
   Dastouri, Pouya
   Scherer, Saja
   Pietramaggiori, Giorgio
   Orgill, Dennis P.
TI Waveform optimization of the Vacuum Assisted Closure device
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Meeting Abstract
CT 95th Annual Clinical Congress of the American-College-of-Surgeons/64th
   Annual Sessions of the Owen H Wangensteen Forum on Fundamental Surgical
   Problems
CY OCT 11-15, 2009
CL Chicago, IL
SP Amer Coll Surg
C1 [Helm, Douglas L.; Dastouri, Pouya; Scherer, Saja; Pietramaggiori, Giorgio; Orgill, Dennis P.] Brigham & Womens Hosp, Boston, MA 02115 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital
RI PIETRAMAGGIORI, Giorgio/HJA-1920-2022; Orgill, Dennis/H-7596-2019
NR 0
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD SEP
PY 2009
VL 209
IS 3
SU S
BP S77
EP S77
DI 10.1016/j.jamcollsurg.2009.06.188
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 493RJ
UT WOS:000269755300168
DA 2026-07-24
ER

PT J
AU Jin, SY
   Chen, M
   Wang, FY
   Wang, F
AF Jin, Shi-Ying
   Chen, Mei
   Wang, Feng-Yuan
   Wang, Fei
TI Applying Intravenous Immunoglobulin and Negative-Pressure Wound Therapy
   to Treat Refractory Pyoderma Gangrenosum: A Case Report
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE pyoderma gangrenosum; neutrophilic dermatosis; negative-pressure wound
   therapy; intravenous immunoglobulin; ulcer
AB Pyoderma gangrenosum (PG) is a rare chronic neutrophilic dermatosis that causes undermining ulcers. Unfortunately, standardization of PG treatment remains a challenge. In this article, we describe a case in which a 69-year-old man presented with a painful ulcer on the right lower leg. The diagnosis of PG was made after excluding other diseases. He had a history of PG on his left lower leg 2 years earlier and was cured by the treatment of systemic corticosteroids and cyclosporin A for 43 days. However, such a treatment was not effective this time. Hence, we applied intravenous immunoglobulin and negative-pressure wound therapy, and the patient was cured. Altogether, this case supports the use of intravenous immunoglobulin as an effective adjuvant for refractory PG, and indicates negative-pressure wound therapy as a treatment option to advance ulcer healing under adequate immunosuppression.
C1 [Jin, Shi-Ying; Chen, Mei; Wang, Feng-Yuan; Wang, Fei] Southeast Univ, Zhongda Hosp, Nanjing, Jiangsu, Peoples R China.
C3 Southeast University - China
RP Wang, F (通讯作者)，87 Dingjiaqiao Rd, Nanjing 210009, Jiangsu, Peoples R China.
EM ffwangfei@163.com
OI Jin, Shiying/0000-0003-1278-0123
CR Adisen E, 2016, INT J LOW EXTR WOUND, V15, P148, DOI 10.1177/1534734616639172
   Alavi A, 2017, AM J CLIN DERMATOL, V18, P355, DOI 10.1007/s40257-017-0251-7
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Baliu-Piqué C, 2017, AUSTRALAS J DERMATOL, V58, pE83, DOI 10.1111/ajd.12498
   Binus AM, 2011, BRIT J DERMATOL, V165, P1244, DOI 10.1111/j.1365-2133.2011.10565.x
   Crowson AN, 2003, J CUTAN PATHOL, V30, P97
   Haag CK, 2020, J DERMATOL TREAT, V31, P723, DOI 10.1080/09546634.2019.1606888
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Ormerod AD, 2015, BMJ-BRIT MED J, V350, DOI 10.1136/bmj.h2958
   Pichler M, 2017, J EUR ACAD DERMATOL, V31, pE61, DOI 10.1111/jdv.13727
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   Song H, 2018, BRIT J DERMATOL, V178, P363, DOI 10.1111/bjd.15850
   Xu A, 2020, J AM ACAD DERMATOL, V83, P425, DOI 10.1016/j.jaad.2019.08.001
NR 13
TC 6
Z9 8
U1 0
U2 4
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD JUN
PY 2021
VL 20
IS 2
BP 158
EP 161
AR 1534734620940459
DI 10.1177/1534734620940459
EA JUL 2020
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA SO1ZP
UT WOS:000554385400001
PM 32734793
DA 2026-07-24
ER

PT J
AU Sartipy, U
   Lockowandt, U
   Gäbel, J
   Jidéus, L
   Dellgren, G
AF Sartipy, Ulrik
   Lockowandt, Ulf
   Gabel, Jakob
   Jideus, Lena
   Dellgren, Goran
TI Cardiac rupture during vacuum-assisted closure therapy
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
AB Vacuum-assisted closure therapy is a recently introduced technique for treatment of deep sternal wound infections after cardiac surgery. We present five cases of vacuumassisted closure therapy-related major bleeding complications due to rupture of the right ventricle. This potentially lethal complication may be avoided by covering the heart with protective layers of paraffin gauze dressings.
C1 Karolinska Univ Hosp, Dept Cardiothorac Surg & Anesthesiol, Karolinska Inst, SE-17176 Stockholm, Sweden.
   Sahlgrens Univ Hosp, Dept Cardiothorac Surg, S-41345 Gothenburg, Sweden.
   Univ Uppsala Hosp, Dept Cardiothorac Surg, Uppsala, Sweden.
C3 Karolinska Institutet; Karolinska University Hospital; Sahlgrenska
   University Hospital; Uppsala University; Uppsala University Hospital
RP Sartipy, U (通讯作者)，Karolinska Univ Hosp, Dept Cardiothorac Surg & Anesthesiol, Karolinska Inst, SE-17176 Stockholm, Sweden.
EM ulrik.sartipy@karolinska.se
RI Sartipy, Ulrik/E-9780-2014
OI Sartipy, Ulrik/0000-0003-2707-0263
CR Abu-Omar Y, 2003, ANN THORAC SURG, V76, P974, DOI 10.1016/S0003-4975(03)00180-2
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
NR 4
TC 66
Z9 81
U1 0
U2 5
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD SEP
PY 2006
VL 82
IS 3
BP 1110
EP 1111
DI 10.1016/j.athoracsur.2006.01.060
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 076ZD
UT WOS:000239996300060
PM 16928555
DA 2026-07-24
ER

PT J
AU Sarman, H
   Muezzinoglu, US
   Memisoglu, K
   Baran, T
AF Sarman, Hakan
   Muezzinoglu, Umit S.
   Memisoglu, Kaya
   Baran, Tuncay
TI Vacuum-assisted closure for skin necrosis after revision total knee
   arthroplasty
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Revision total knee arthroplasty; Skin necrosis; Therapy;
   Vacuum-assisted closure
ID WOUND COMPLICATIONS
AB Although skin necrosis following total knee arthroplasty or revision total knee arthroplasty is rare, it may cause severe complications. Skin changes begin with superficial infections and may result in removal of the prosthesis. Treatment of skin necrosis is an important factor, which determines the prognosis of the prosthesis. Several techniques have been defined for sufficient closure. In this article, we present the case of a patient who was treated for skin necrosis that developed after knee revision arthroplasty, using serial debridement, convergence sutures and an intermittent vacuum-assisted closure device (KCI Inc., San Antonio, TX).
C1 [Sarman, Hakan] Abant Izzet Baysal Univ, Dept Orthoped & Traumatol, Bolu, Turkey.
   [Muezzinoglu, Umit S.; Memisoglu, Kaya; Baran, Tuncay] Kocaeli Univ, Dept Orthoped & Traumatol, Kocaeli, Turkey.
C3 Abant Izzet Baysal University; Kocaeli University
RP Sarman, H (通讯作者)，Abant Izzet Baysal Univ, Sch Med, Dept Orthoped & Traumatol, Bolu, Turkey.
EM hakansarman@yahoo.com
RI Sarman, Hakan/B-5281-2015; /AAK-3514-2020
OI Sarman, Hakan/0000-0003-2221-4731; 
CR Ayers DC, 1997, J BONE JOINT SURG AM, V79A, P278, DOI 10.2106/00004623-199702000-00018
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   Garbedian S, 2011, ORTHOPEDICS, V34, pE516, DOI 10.3928/01477447-20110714-42
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Menderes A, 2002, KNEE, V9, P215, DOI 10.1016/S0968-0160(02)00010-8
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NR 17
TC 2
Z9 3
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2016
VL 13
IS 5
BP 843
EP 847
DI 10.1111/iwj.12390
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA EB8UV
UT WOS:000387667600090
PM 25597628
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Aldridge, B
   Ladd, AP
   Kepple, J
   Wingle, T
   Ring, C
   Kokoska, ER
AF Aldridge, Beau
   Ladd, Alan P.
   Kepple, Jacqueline
   Wingle, Teresa
   Ring, Christopher
   Kokoska, Evan R.
TI Negative pressure wound therapy for initial management of giant
   omphalocele
SO AMERICAN JOURNAL OF SURGERY
LA English
DT Article
DE Omphalocele; Wound VAC; Negative pressure wound therapy
AB BACKGROUND: Current treatment of giant omphalocele includes "paint and wait'' or placement of mesh or silo. These methods are associated with high complication rates. We propose negative pressure wound therapy as an alternative.
   METHODS: Patients born between 2009 and 2014 with giant omphalocele were included. Outcomes analyzed were duration of therapy, time to full enteral feeds, treatment related complications, wound surface area over time, type, and time to definitive closure.
   RESULTS: Eight patients were reviewed. The median duration of therapy was 68 days. Median time to full enteral feeds was 19 days. There were no treatment discontinuations or complications including sac ruptures, wound infections, or fistulas. Wound contraction stopped at 2 months or around 7 cm(2). All surviving patients underwent definitive closure.
   CONCLUSIONS: Negative pressure wound therapy is a safe and effective treatment for giant omphalocele that allows feeding, has a low complication rate, and is completed in 2 months. (C) 2016 Elsevier Inc. All rights reserved.
C1 [Aldridge, Beau; Kepple, Jacqueline; Wingle, Teresa; Ring, Christopher; Kokoska, Evan R.] Peyton Manning Childrens Hosp, Dept Pediat Surg, 2001 W 86th St, Indianapolis, IN 46260 USA.
   [Ladd, Alan P.] Indiana Univ, Sch Med, Dept Surg, Riley Hosp Children, Indianapolis, IN 46202 USA.
C3 Indiana University Health; James Whitcomb Riley Hospital Children;
   Indiana University System; Indiana University Indianapolis
RP Kokoska, ER (通讯作者)，Peyton Manning Childrens Hosp, Dept Pediat Surg, 2001 W 86th St, Indianapolis, IN 46260 USA.
EM erkokosk@stvincent.org
CR Binet A, 2013, J PLAST RECONSTR AES, V66, pE373, DOI 10.1016/j.bjps.2013.05.010
   Canfield MA, 2006, BIRTH DEFECTS RES A, V76, P747, DOI 10.1002/bdra.20294
   Coran A, 2012, PEDIAT SURG, P973
   Elin SH, 2012, J PEDIATR SURG, V47, P494
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   Mitanchez D, 2010, J PEDIATR SURG, V45, P1727, DOI 10.1016/j.jpedsurg.2010.04.011
   van Eijck FC, 2011, J PEDIATR SURG, V46, P482, DOI 10.1016/j.jpedsurg.2010.08.050
NR 7
TC 20
Z9 25
U1 0
U2 3
PU EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
PI BRIDGEWATER
PA 685 ROUTE 202-206 STE 3, BRIDGEWATER, NJ 08807 USA
SN 0002-9610
EI 1879-1883
J9 AM J SURG
JI Am. J. Surg.
PD MAR
PY 2016
VL 211
IS 3
BP 605
EP 608
DI 10.1016/j.amjsurg.2015.11.009
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DE5YR
UT WOS:000370709900041
PM 26778271
DA 2026-07-24
ER

PT J
AU Wolvos, T
AF Wolvos, Tom
TI THE EVOLUTION OF NEGATIVE PRESSURE WOUND THERAPY: NEGATIVE PRESSURE
   WOUND THERAPY WITH INSTILLATION
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE negative pressure wound therapy with instillation; wound healing; dwell
   time; instillation therapy
ID SALINE INSTILLATION; FIBRIN MATRIX; PROLIFERATION; CONJUNCTION; MODEL
AB Complex wounds pose a considerable burden to patients and the health-care system. The development of negative pressure wound therapy (NPWT) has revolutionised the treatment of these wounds. NPWT helps create a favourable wound healing environment by removing infectious material, decreasing oedema and promoting perfusion and granulation tissue formation. Additionally, NPWT has been reported to help reduce time to wound closure and length of hospital stay. Modifications of this foundation of wound care have added intermittent instillation with a dwell time to NPWT (NPWTi-d). This new system offers more comprehensive wound care through automated wound irrigation, allowing more control over the wound environment and the opportunity to deliver topical wound solutions directly to the affected tissues. A comparison between the two therapies, NPWT and NPWTi-d, is described, and two real-world applications of NPWTi-d are presented.
C1 Scottsdale Healthcare Osborn Med Ctr, Gen Surg, Scottsdale, AZ 85251 USA.
C3 Scottsdale Healthcare Osborn
RP Wolvos, T (通讯作者)，Scottsdale Healthcare Osborn Med Ctr, Gen Surg, Scottsdale, AZ 85251 USA.
EM twolvosmd@scottsdalesurgical.com
FU KCI, an Acelity company, Edinburgh, Scotland
FX TW presented as a faculty member during the 2014 International Surgical
   Wound Forum (ISWF), an annual educational event sponsored by KCI, an
   Acelity company, held in 2014 in Edinburgh, Scotland. This article is
   part of a KCI-funded educational supplement based on 2014 ISWF faculty
   presentations about wound-care strategies using negative pressure wound
   therapy. Acelity assisted with the editorial review of the manuscript.
   TW also has a consultant agreement with KCI, an Aecilty company.
CR Brinkert D, 2013, INT WOUND J, V10, P56, DOI 10.1111/iwj.12176
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NR 21
TC 21
Z9 29
U1 0
U2 20
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
J9 J WOUND CARE
JI J. Wound Care
PD APR
PY 2015
VL 24
IS 4
SU S
BP 15
EP 20
DI 10.12968/jowc.2015.24.Sup4b.15
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA CG1YK
UT WOS:000353071900003
PM 25853644
DA 2026-07-24
ER

PT J
AU Ding, JR
   Zhu, YQ
   Ge, HQ
   Chen, H
   Wang, LM
   Xie, SX
   Zhang, SW
   Deng, YM
   Yang, R
   Guo, HQ
AF Ding, Jiarong
   Zhu, Yiqi
   Ge, Huaqiang
   Chen, Hui
   Wang, Liangmei
   Xie, Shangxun
   Zhang, Shiwei
   Deng, Yongming
   Yang, Rong
   Guo, Hongqian
TI Negative Pressure Wound Therapy for Patients With Complicated
   Mucocutaneous Separation Following Ileal Conduit Urinary Diversion
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Case series; Ileal conduit; Mucocutaneous separation; Negative pressure
   wound therapy
ID MANAGEMENT
AB BACKGROUND:Mucocutaneous separation (MCS) is one of the early stomal complications of ileal conduit diversion after radical cystectomy. It can result in abdominal infection and sepsis, prolonging patient recovery. Negative pressure wound therapy (NPWT) has been widely used for abdominal wounds after orthopedic and burn surgery. This case series describes its use in complicated MCS and ostomy retraction after ileal conduit diversion.CASES:We describe a case series of 3 patients with moderate to severe MCS with and without infection after robot-assisted radical cystectomy with ileal conduit diversion. Our patients were treated with NPWT to avoid infection and create a satisfactory environment for healing MCS. After 2 to 4 weeks of NPWT, all 3 patients had normal micturition function with no additional peristomal wounds or complications.CONCLUSION:Negative pressure wound therapy may be used in the management of complicated MCS after ileal conduit diversion.
C1 [Ding, Jiarong; Yang, Rong; Guo, Hongqian] Nanjing Univ Chinese Med, Nanjing Drum Tower Hosp, Clin Coll, Dept Urol, 321 Zhongshan Rd, Nanjing 210008, Jiangsu, Peoples R China.
   [Zhu, Yiqi; Chen, Hui; Wang, Liangmei; Zhang, Shiwei; Deng, Yongming] Nanjing Univ Med Sch, Nanjing Drum Tower Hosp, Dept Urol, Affiliated Hosp, Nanjing, Jiangsu, Peoples R China.
   [Ge, Huaqiang] Nanjing Univ Med Sch, Nanjing Drum Tower Hosp, Dept Burn & Plast Surg, Affiliated Hosp, Nanjing, Jiangsu, Peoples R China.
   [Xie, Shangxun] Wenzhou Med Univ, Affiliated Hosp 2, Dept Urol, Wenzhou, Zhejiang, Peoples R China.
   [Xie, Shangxun] Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou, Zhejiang, Peoples R China.
C3 Nanjing University; Nanjing University of Chinese Medicine; Nanjing
   University; Nanjing University; Wenzhou Medical University; Wenzhou
   Medical University
RP Yang, R; Guo, HQ (通讯作者)，Nanjing Univ Chinese Med, Nanjing Drum Tower Hosp, Clin Coll, Dept Urol, 321 Zhongshan Rd, Nanjing 210008, Jiangsu, Peoples R China.
EM gydjiarong@126.com; 354599496@qq.com; 845162074@qq.com;
   845162074@qq.com; 13770835727@163.com; sipangxie@yeah.net;
   zsw999@hotmail.com; dr.dym@foxmail.com; doctoryr@gmail.com;
   dr.ghq@nju.edu.cn
FU National Natural Science Foundation of China [82172691, 81772727,
   81972388, 81772710]; Nanjing Health Science and Technology Development
   Fund [ZKX19011]
FX The authors thank Hui Chen, BSN, ET, who provided guidance and
   assistance during the management of the three complex stomas discussed
   in this paper.r This study was supported by the National Natural Science
   Foundation of China (82172691, 81772727, 81972388, and 81772710) and
   Nanjing Health Science and Technology Development Fund (ZKX19011).
CR Bayci A, 2018, J WOUND OSTOMY CONT, V45, P468, DOI 10.1097/WON.0000000000000471
   Berti-Hearn Linda, 2019, Home Healthc Now, V37, P248, DOI [10.1097/nhh.0000000000000792, 10.1097/NHH.0000000000000792]
   Bilgin IA, 2020, J WOUND OSTOMY CONT, V47, P72, DOI 10.1097/WON.0000000000000611
   Carlsson E, 2016, OSTOMY WOUND MANAG, V62, P34
   Dwivedi MK, 2017, J WOUND OSTOMY CONT, V44, P343, DOI 10.1097/WON.0000000000000333
   Hall KD, 2019, J WOUND OSTOMY CONT, V46, P251, DOI 10.1097/WON.0000000000000516
   Koc U, 2017, OSTOMY WOUND MANAG, V63, P28
   Krishnamurty DM, 2017, CLIN COLON RECT SURG, V30, P193, DOI 10.1055/s-0037-1598160
   Li Chun-Mei, 2019, Hua Xi Kou Qiang Yi Xue Za Zhi, V37, P62, DOI 10.7518/hxkq.2019.01.012
   Murken DR, 2019, CLIN COLON RECT SURG, V32, P176, DOI 10.1055/s-0038-1676995
   O'Flynn Sinead Kelly, 2018, Br J Community Nurs, V23, P382, DOI [10.12968/bjcn.2018.23.8.382, 10.12968/bjcn.2018.23.8.382]
   Tsujinaka S, 2020, J ANUS RECTUM COLON, V4, P25, DOI 10.23922/jarc.2019-032
   Zhang D, 2020, WOUND MANAG PREV, V66, P22, DOI 10.25270/wmp.2020.8.2225
   Zhou HY, 2019, J WOUND OSTOMY CONT, V46, P413, DOI 10.1097/WON.0000000000000574
NR 14
TC 0
Z9 1
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD SEP-OCT
PY 2023
VL 50
IS 5
BP 420
EP 426
DI 10.1097/WON.0000000000001000
PG 7
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA S0DP8
UT WOS:001067966400015
PM 37713355
DA 2026-07-24
ER

PT J
AU Gomez, G
   Sie, KCY
   Osterbauer, B
   Arom, G
   Kochhar, A
AF Gomez, Gabriel
   Sie, Kathleen C. Y.
   Osterbauer, Beth
   Arom, Gabriel
   Kochhar, Amit
TI Salvage of Infected Alloplastic Ear Reconstructions via Negative
   Pressure Wound Therapy
SO LARYNGOSCOPE
LA English
DT Article
DE ear deformity; microtia; negative-pressure wound therapy; pediatric;
   porous polyethylene PPE framework
AB This is the first description of Negative Pressure Wound Therapy (NPWT) use in rescuing alloplastic ear reconstructions. Previously considered a sign of certain impending failure, severe infections with frank purulence can be salvaged. As a more recently developed technique, porous polyethylene (PPE) ear reconstruction provides benefits when compared to rib techniques. Increasing surgeon awareness of complication management may lead to further adoption of the technique and improve reconstructive results. Described herein are two cases of draining infections following PPE ear reconstruction that were salvaged with satisfactory results. Laryngoscope, 2024
   This is the first description of Negative Pressure Wound Therapy (NPWT) use in rescuing alloplastic ear reconstructions. Previously considered a sign of certain impending failure, severe infections with frank purulence can be salvaged. As a more recently developed technique, porous polyethylene (PPE) ear reconstruction provides benefits when compared to rib techniques. Increasing surgeon awareness of complication management may lead to further adoption of the technique and improve reconstructive results. image
C1 [Gomez, Gabriel; Osterbauer, Beth; Arom, Gabriel; Kochhar, Amit] Childrens Hosp Los Angeles, Div Otolaryngol Head & Neck Surg, Los Angeles, CA USA.
   [Sie, Kathleen C. Y.] Seattle Childrens, Div Otolaryngol Head & Neck Surg, Seattle, WA USA.
   [Gomez, Gabriel] Childrens Hosp Los Angeles, Div Otolaryngol Head & Neck Surg, 4650 Sunset Blvd MS58, Los Angeles, CA 90027 USA.
C3 Children's Hospital Los Angeles; Seattle Children's Hospital; Children's
   Hospital Los Angeles
RP Gomez, G (通讯作者)，Childrens Hosp Los Angeles, Div Otolaryngol Head & Neck Surg, 4650 Sunset Blvd MS58, Los Angeles, CA 90027 USA.
EM ggomez@chla.usc.edu
CR Lewin S, 2015, FACIAL PLAST SURG, V31, P617, DOI 10.1055/s-0035-1567890
   Mir A, 2019, LARYNGOSCOPE, V129, P671, DOI 10.1002/lary.27262
   Sasaki K, 2021, J PLAST RECONSTR AES, V74, P1380, DOI 10.1016/j.bjps.2020.11.010
   Stephan S, 2018, FACIAL PLAST SURG CL, V26, P69, DOI 10.1016/j.fsc.2017.09.009
   TANZER R C, 1959, Plast Reconstr Surg Transplant Bull, V23, P1
NR 5
TC 2
Z9 2
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0023-852X
EI 1531-4995
J9 LARYNGOSCOPE
JI Laryngoscope
PD SEP
PY 2024
VL 134
IS 9
BP 4122
EP 4125
DI 10.1002/lary.31403
EA MAR 2024
PG 4
WC Medicine, Research & Experimental; Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Otorhinolaryngology
GA A9C2D
UT WOS:001187610600001
PM 38506413
DA 2026-07-24
ER

PT J
AU Ribeiro, LM
   Guerra, AS
AF Ribeiro, Luis Mata
   Guerra, Ana Silva
TI Hidradenitis Suppurativa: Combined Treatment with Dermal Template, Skin
   Graft and Negative Pressure Wound Therapy, a Case Study
SO ACTA MEDICA PORTUGUESA
LA Portuguese
DT Article
DE Hidradenitis Suppurativa; Negative-Pressure Wound Therapy; Skin
   Transplantation
ID AXILLARY HIDRADENITIS; SURGICAL-TREATMENT; ACNE INVERSA; SURGERY;
   DRESSINGS; FLAP
AB Hidrosadenitis supurativa is a chronic inflammatory disease with great physical and psychological impact. Although conservative treatments may be effective in mild forms of the disease, extensive surgical resection and reconstruction are necessary in more severe forms of the disease. The purpose of this paper is to describe our two-stage reconstructive procedure regarding this kind of disease. We present a clinical case of a patient with severe, bilateral axillary hidrosadenitis. In the first surgical step we excised the lesions and applied the artificial dermis secured with negative pressure wound therapy. In the second step we used a split thickness skin graft to close the wound and again applied negative pressure wound therapy. The graft take was very good, without complications. The cosmetic outcome is acceptable and shoulder mobility was not compromised. No recurrence was detected (nine months follow up).
C1 [Ribeiro, Luis Mata; Guerra, Ana Silva] Ctr Hosp Lisboa Cent, Hosp Sao Jose, Serv Cirurgia Plast Reconstrut & Estet, Lisbon, Portugal.
   [Guerra, Ana Silva] Hosp CUF Descobertas, Serv Cirurgia Plast Reconstrut & Estet, Lisbon, Portugal.
C3 Universidade de Lisboa; Centro Hospitalar de Lisboa Central, EPE
RP Ribeiro, LM (通讯作者)，Ctr Hosp Lisboa Cent, Hosp Sao Jose, Serv Cirurgia Plast Reconstrut & Estet, Lisbon, Portugal.
EM Luis1989ribeiro@gmail.com
RI Mata Ribeiro, Luís/AAZ-2661-2020
OI Mata Ribeiro, Luís/0000-0002-4714-8737
CR [Anonymous], 1989, Axillary hyperhidrosis, apocrine bromhidrosis, hidradenitis suppurativa and familial benign pemphigus: surgical approach
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NR 14
TC 1
Z9 3
U1 0
U2 1
PU ORDEM MEDICOS
PI LISBON
PA AV ALMIRANTE GAGO COUTINHO, 151, LISBON, 1749-084, PORTUGAL
SN 1646-0758
J9 ACTA MEDICA PORT
JI Acta Medica Port.
PD JAN
PY 2018
VL 31
IS 1
BP 59
EP 62
DI 10.20344/amp.8656
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA FW6YF
UT WOS:000425465600011
PM 29573770
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Ruiz, E
   Moreno, P
   Poveda, DS
   Fernández, AM
   González, FJ
   Algar, FJ
   Cerezo, F
   Baamonde, C
   Salvatierra, A
   Alvarez, A
AF Ruiz, Eloisa
   Moreno, Paula
   Sebastian Poveda, David
   Maria Fernandez, Alba
   Javier Gonzalez, Francisco
   Javier Algar, Francisco
   Cerezo, Francisco
   Baamonde, Carlos
   Salvatierra, Angel
   Alvarez, Antonio
TI Case Report on Sternal Osteomyelitis by Trichosporon inkin
   Complicating Lung Transplantation: Effective Treatment With
   Vacuum-Assisted Closure and Surgical Reconstruction
SO TRANSPLANTATION PROCEEDINGS
LA English
DT Article; Proceedings Paper
CT 12th Congress of the
   Andalusian-Society-of-Organ-and-Tissue-Transplantation (SATOT)
CY JUN 09-10, 2021
CL ELECTR NETWORK
SP Andalusian Soc Organ & Tissue Transplantat
ID MEDIASTINITIS; INFECTIONS; HEART
AB Sternal osteomyelitis is a serious complication that significantly increases morbidity and mortality after thoracic surgery. We describe a case of sternal osteomyelitis by Trichosporon inkin following lung transplantation and the excellent results achieved with vacuum-assisted closure therapy.
C1 [Ruiz, Eloisa; Moreno, Paula; Sebastian Poveda, David; Maria Fernandez, Alba; Javier Gonzalez, Francisco; Javier Algar, Francisco; Cerezo, Francisco; Baamonde, Carlos; Salvatierra, Angel; Alvarez, Antonio] Univ Hosp Reina Sofia, Dept Thorac Surg & Lung Transplantat, Avda Menendez Pidal S-N, Cordoba 14004, Spain.
RP Alvarez, A (通讯作者)，Univ Hosp Reina Sofia, Dept Thorac Surg & Lung Transplantat, Avda Menendez Pidal S-N, Cordoba 14004, Spain.
EM aalvarez53@gmail.com
RI /E-4530-2015; Gonzalez, Fernando/AFQ-4244-2022; Alvarez Kindelan,
   Antonio/AAM-6126-2021
OI Fernández González, Alba María/0000-0001-6426-5460; Alvarez Kindelan,
   Antonio/0000-0003-1531-9543
CR Abid Q, 2003, ANN THORAC SURG, V75, P1565, DOI 10.1016/S0003-4975(02)04905-6
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Braxton JH, 2000, ANN THORAC SURG, V70, P2004, DOI 10.1016/S0003-4975(00)01814-2
   Christie JD, 2010, J HEART LUNG TRANSPL, V29, P1104, DOI 10.1016/j.healun.2010.08.004
   Davies F, 2006, J CLIN MICROBIOL, V44, P2657, DOI 10.1128/JCM.00208-06
   GUEHO E, 1994, MYCOSES, V37, P3, DOI 10.1111/j.1439-0507.1994.tb00277.x
   Jonkers D, 2003, EUR J CARDIO-THORAC, V23, P97, DOI 10.1016/S1010-7940(02)00662-0
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   Speich R, 2001, CLIN INFECT DIS, V33, pS58, DOI 10.1086/320906
NR 9
TC 5
Z9 6
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0041-1345
EI 1873-2623
J9 TRANSPL P
JI Transplant. Proc.
PD JAN-FEB
PY 2022
VL 54
IS 1
BP 54
EP 56
DI 10.1016/j.transproceed.2021.09.062
EA FEB 2022
PG 3
WC Immunology; Surgery; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Immunology; Surgery; Transplantation
GA YU2FP
UT WOS:000751863500017
PM 34876268
DA 2026-07-24
ER

PT J
AU Archdeacon, MT
   Messerschmitt, P
AF Archdeacon, MT
   Messerschmitt, P
TI Modern Papineau technique with vacuum-assisted closure
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE Papineau; bone graft; vacuum-assisted closure; wound; osteomyelitis
ID INFECTED TIBIAL NONUNION; CHRONIC OSTEOMYELITIS; MANAGEMENT; EXCISION;
   THERAPY
AB We describe a contemporary modification of the Papineau technique by implementing a vacuum-assisted closure (V.A.C.(R)) device in lieu of wet-to-dry dressing changes. The method makes use of a protocol similar to that of Papineau and others for the treatment of chronic osteomyelitis. This protocol includes aggressive excisional debridement of infected or necrotic bone, open bone grafting with cancellous autograft, vacuum-assisted wound closure by secondary intent, and eradication of chronic infection with concomitant parenteral antibiotics. A representative case report is included to illustrate the technique.
C1 Univ Cincinnati, Coll Med, Dept Orthopaed Surg, Cincinnati, OH 45267 USA.
C3 University System of Ohio; University of Cincinnati
RP Archdeacon, MT (通讯作者)，Univ Cincinnati, Coll Med, Dept Orthopaed Surg, POB 670212, Cincinnati, OH 45267 USA.
EM michael.archdeacon@uc.edu
OI Archdeacon, Michael/0000-0002-4171-0303
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 12
TC 32
Z9 47
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0890-5339
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD FEB
PY 2006
VL 20
IS 2
BP 134
EP 137
DI 10.1097/01.bot.0000184147.82824.7c
PG 4
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 014YI
UT WOS:000235516500009
PM 16462567
DA 2026-07-24
ER

PT J
AU Sherman, G
   Shulman-Manor, O
   Dagan, O
   Livni, G
   Scheuerman, O
   Amir, G
   Frenkel, G
   Levy, I
AF Sherman, Gilad
   Shulman-Manor, Orit
   Dagan, Ovadia
   Livni, Gilat
   Scheuerman, Oded
   Amir, Gabriel
   Frenkel, George
   Levy, Itzhak
TI Vacuum-Assisted Closure for the Treatment of Deep Sternal Wound
   Infection After Pediatric Cardiac Surgery
SO PEDIATRIC CRITICAL CARE MEDICINE
LA English
DT Article
DE children; sternal wound infection; vacuum-assisted closure
ID POST-STERNOTOMY MEDIASTINITIS; POSTSTERNOTOMY MEDIASTINITIS;
   POSTOPERATIVE MEDIASTINITIS; NEGATIVE PRESSURES; MANAGEMENT; DRAINAGE
AB Objectives:
   Vacuum-assisted closure is being increasingly used to treat deep sternal wound infection following cardiac surgery, but most of the data refer to adults. This study investigated the safety and efficacy of vacuum-assisted closure in pediatric patients.
   Design:
   Retrospective file review.
   Setting:
   Tertiary pediatric medical center.
   Patients:
   All children with deep sternal wound infection treated with vacuum-assisted closure in 2003-2016.
   Interventions:
   Epidemiological, clinical, and microbiological data were collected from the medical records.
   Measurements and Main Results:
   The cohort included 50 patients (0.9% of cardiac patients operated during the study period) of median age 6.5 months (interquartile range, 2-12.75 mo; range, 1 wk to 14 yr) and median weight 5.1 kg (interquartile range, 4-9.75 kg). The most frequent heart defects were tetralogy of Fallot (22%) and ventricular septal defect (20%); 38% of patients had cyanotic heart disease. Deep sternal wound infections appeared a median of 10 days postoperatively (interquartile range, 7-14 d; range 3-100 d). Vacuum-assisted closure was applied a median of 13 days postoperatively (interquartile range, 10-18.5 d; range, 5-103 d) for a median duration of 10 days (interquartile range, 7-13.25 d; range, 1-21 d). Wound cultures were positive in 48 patients (96%); most isolates were Gram-positive (76%). The main bacterial pathogen was methicillin-susceptible Staphylococcus aureus (61%). Most patients were treated with cloxacillin for a median of 38 days (interquartile range, 28-42 d; range, 9-189 d). There were no statistically significant differences in clinical or treatment characteristics between bacteremic (56%) and nonbacteremic patients. Compared with older patients, infants less than 3 months old (36%) had a significantly longer hospitalization time (41 vs 25 d; p = 0.001) and higher Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery Mortality Category (3 vs 2; p = 0.003). All cases except one (contact dermatitis) were uneventful. In 10 patients, wounds were closed surgically after vacuum-assisted closure. Two patients required a pectoralis flap, both treated before 2005. One of the two deaths was infection-related.
   Conclusions:
   Vacuum-assisted closure is a feasible treatment option of deep sternal wound infection after pediatric cardiac surgery and was not associated with independent morbidity.
C1 [Sherman, Gilad; Scheuerman, Oded; Levy, Itzhak] Schneider Childrens Med Ctr Israel, Infect Dis Unit, Petah Tiqwa, Israel.
   [Sherman, Gilad; Shulman-Manor, Orit; Dagan, Ovadia; Livni, Gilat; Scheuerman, Oded; Amir, Gabriel; Levy, Itzhak] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel.
   [Shulman-Manor, Orit; Dagan, Ovadia; Amir, Gabriel; Frenkel, George] Schneider Childrens Med Ctr Israel, Pediat Cardiac Intens Care Unit, Petah Tiqwa, Israel.
   [Livni, Gilat] Schneider Childrens Med Ctr Israel, Dept Pediat A, Petah Tiqwa, Israel.
   [Scheuerman, Oded] Schneider Childrens Med Ctr Israel, Dept Pediat B, Petah Tiqwa, Israel.
C3 Tel Aviv University; Tel Aviv University; Sackler Faculty of Medicine;
   Tel Aviv University; Tel Aviv University; Tel Aviv University
RP Levy, I (通讯作者)，Schneider Childrens Med Ctr Israel, Infect Dis Unit, Petah Tiqwa, Israel.; Levy, I (通讯作者)，Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel.
EM itzhakl@clalit.org.il
RI Sherman, Gilad/MTG-4350-2025
OI Sherman, Gilad/0000-0001-9290-6667
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   Ugaki S, 2010, INTERACT CARDIOV TH, V11, P247, DOI 10.1510/icvts.2010.235903
   Yu AW, 2013, INTERACT CARDIOV TH, V17, P861, DOI 10.1093/icvts/ivt326
NR 25
TC 9
Z9 15
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1529-7535
EI 1947-3893
J9 PEDIATR CRIT CARE ME
JI Pediatr. Crit. Care Med.
PD FEB
PY 2020
VL 21
IS 2
BP 150
EP 155
DI 10.1097/PCC.0000000000002131
PG 6
WC Critical Care Medicine; Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Pediatrics
GA LH6KK
UT WOS:000528892100011
PM 31568260
DA 2026-07-24
ER

PT J
AU Steenvoorde, P
   van Engeland, A
   Oskam, J
AF Steenvoorde, P
   van Engeland, A
   Oskam, J
TI Vacuum-assisted closure therapy and oral anticoagulation therapy
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Letter
C1 Rijnland Hosp Leiderdorp, Dept Surg, NL-2353 GA Leiderdorp, Netherlands.
C3 Rijnland Hospital
RP Steenvoorde, P (通讯作者)，Rijnland Hosp Leiderdorp, Dept Surg, Simon Smitweg 1, NL-2353 GA Leiderdorp, Netherlands.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Voinchet V, 1996, Ann Chir Plast Esthet, V41, P583
   Wanner MB, 2003, SCAND J PLAST RECONS, V37, P28
   Webb LX, 2001, UNFALLCHIRURG, V104, P918, DOI 10.1007/PL00002776
NR 4
TC 7
Z9 9
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JUN
PY 2004
VL 113
IS 7
BP 2220
EP 2221
DI 10.1097/01.PRS.0000123603.32963.11
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 827RI
UT WOS:000221917700059
PM 15253223
DA 2026-07-24
ER

PT J
AU Cooper, SM
   Young, E
AF Cooper, SM
   Young, E
TI Topical negative pressure
SO INTERNATIONAL JOURNAL OF DERMATOLOGY
LA English
DT Editorial Material
ID VACUUM-ASSISTED CLOSURE; WOUND CONTROL
C1 Amersham Hosp, Dermatol Unit, Amersham HP7 0JD, Bucks, England.
RP Cooper, SM (通讯作者)，Amersham Hosp, Dermatol Unit, Amersham HP7 0JD, Bucks, England.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Banwell P, 1998, BRIT J PLAST SURG, V51, P79, DOI 10.1016/S0007-1226(98)80142-2
   Banwell P E, 1999, J Wound Care, V8, P79
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   FLETCHER J, 1997, J WOUND CARE, V6, P398
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   *KCI INT, 1999, V A C OPERATIONS SUM
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   RYAN TJ, 1993, PHYSICAL FACTORS ANG
NR 9
TC 4
Z9 18
U1 0
U2 0
PU BLACKWELL SCIENCE LTD
PI OXFORD
PA P O BOX 88, OSNEY MEAD, OXFORD OX2 0NE, OXON, ENGLAND
SN 0011-9059
J9 INT J DERMATOL
JI Int. J. Dermatol.
PD DEC
PY 2000
VL 39
IS 12
BP 896
EP 898
DI 10.1046/j.1365-4362.2000.00157-3.x
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 399EG
UT WOS:000166797900004
PM 11168656
OA Bronze
DA 2026-07-24
ER

PT J
AU Mang, R
   Kovnerystyy, O
   Stege, H
AF Mang, R
   Kovnerystyy, O
   Stege, H
TI Vacuum therapy in a pre- and postsurgical ulcera crurum
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Country Congress on VAC Therapy for Outpatients as well as
   In-Hospital Patients
CY MAY 21-22, 2003
CL Mainz, GERMANY
DE vacuum assisted closure; leg ulcer; necrobiosis lipoidica; basal cell
   carcinoma; wound heating
AB Chronic wounds are often a diagnostic as well as a therapeutic problem. Three case reports depi important differential diagnoses. The importance and efficacy of vacuum assisted closure in a presurgical treatment as well as after mesh graft transplanation will be described.
C1 Univ Klinikum Dusseldorf, Hautklin, Dusseldorf, Germany.
C3 Heinrich Heine University Dusseldorf; Heinrich Heine University
   Dusseldorf Hospital
RP Stege, H (通讯作者)，Moorenstr 5, D-40225 Dusseldorf, Germany.
EM stege@med.uni-duesseldorf.de
CR Gallenkemper G, 1996, PHLEBOLOGIE, V25, P254
   Marinella MA, 2002, LANCET, V360, P1143, DOI 10.1016/S0140-6736(02)11200-1
   Pannier-Fischer F, 2003, HAUTARZT, V54, P1037, DOI 10.1007/s00105-003-0616-0
   Sibbald R Gary, 2003, Ostomy Wound Manage, V49, P52
NR 4
TC 1
Z9 1
U1 0
U2 1
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD MAY
PY 2004
VL 129
SU 1
BP S101
EP S103
DI 10.1055/s-2004-822652
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 826GF
UT WOS:000221816600032
PM 15168302
DA 2026-07-24
ER

PT J
AU Abbitt, D
   Hadley, J
   Choy, K
   McCarter, MD
   Chauhan, A
   Raeburn, CD
   Wikiel, KJ
   Jones, EL
AF Abbitt, Danielle
   Hadley, Jamie
   Choy, Kevin
   McCarter, Martin D.
   Chauhan, Akshay
   Raeburn, Christopher D.
   Wikiel, Krzysztof J.
   Jones, Edward L.
TI Endoluminal Wound Vacuum-Assisted Closure: Bridging the Gap
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Meeting Abstract
CT 8th Annual Own H Wangensteen Scientific Forum and Annual Clinical
   Congress of the American-College-of-Surgeons (ACS)
CY OCT 16-20, 2022
CL San Diego, CA
SP Amer Coll Surg
C1 Univ Colorado, Aurora, CO USA.
   Rocky Mt Reg VA Med Ctr, Aurora, CO USA.
C3 University of Colorado System; University of Colorado Anschutz
RI Chauhan, Akshay/PFR-4434-2026; Jones, Edward/KYV-5676-2024
OI Jones, Edward/0000-0002-1449-8255
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD NOV
PY 2022
VL 235
IS 5
SU 1
BP S77
EP S77
DI 10.1097/01.XCS.0000893528.78520.8d
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 5H7YD
UT WOS:000867889300135
DA 2026-07-24
ER

PT J
AU Schwartz, BF
   Stewart, J
   Mukerji, R
   Bewsy, K
AF Schwartz, BF
   Stewart, J
   Mukerji, R
   Bewsy, K
TI Urologic applications of the vacuum assisted closure device
SO JOURNAL OF UROLOGY
LA English
DT Meeting Abstract
CT 99th Annual Meeting of the American-Urological-Association
CY MAY 08-13, 2004
CL San Francisco, CA
SP Amer Urol Assoc
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0022-5347
J9 J UROLOGY
JI J. Urol.
PD APR
PY 2004
VL 171
IS 4
SU S
BP 20
EP 20
DI 10.1016/S0022-5347(18)37338-5
PG 1
WC Urology & Nephrology
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Urology & Nephrology
GA 807IP
UT WOS:000220495500077
OA Bronze
DA 2026-07-24
ER

PT J
AU Linder, F
   Drott, CJ
   Muhrbeck, M
   Oussi, N
   Osterman, E
AF Linder, Fredrik
   Drott, Carl Johan
   Muhrbeck, Mans
   Oussi, Ninos
   Osterman, Erik
TI Treating emergency laparotomy incisions with negative pressure wound
   therapy
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
C1 [Linder, Fredrik; Osterman, Erik] Uppsala Univ Hosp, Dept Surg & Urol, Uppsala, Sweden.
   [Drott, Carl Johan; Oussi, Ninos] Malar Hosp Eskilstuna, Dept Surg, Eskilstuna, Sweden.
   [Muhrbeck, Mans] Linkoping Univ Hosp, Dept Surg, Linkoping, Sweden.
C3 Uppsala University; Uppsala University Hospital; Linkoping University
RI Osterman, Erik/AAM-1247-2020
OI Osterman, Erik/0000-0003-1621-7872
NR 0
TC 0
Z9 0
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD AUG
PY 2025
VL 112
SU _11
SI SI
MA znaf149.00
BP xi2
EP xi2
DI 10.1093/bjs/znaf149.006
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 6DN7X
UT WOS:001550788800001
OA Bronze
DA 2026-07-24
ER

PT J
AU Alvarez, ML
AF Alvarez, M. L.
TI DELIVERING POSITIVE OUTCOMES FROM NEGATIVE PRESSURE WOUND THERAPY (NPWT)
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Alvarez, M. L.] Riyadh Mil Hosp, Riyadh, Ksa, Saudi Arabia.
C3 Prince Sultan Military Medical City
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1067-1927
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR-APR
PY 2011
VL 19
IS 2
BP A10
EP A10
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 728ML
UT WOS:000287878100009
DA 2026-07-24
ER

PT J
AU Long, MA
   Blevins, A
AF Long, Mary Arnold
   Blevins, Anne
TI Options in Negative Pressure Wound Therapy Five Case Studies
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
C1 [Long, Mary Arnold; Blevins, Anne] Drake Ctr, Cincinnati, OH 45216 USA.
RP Long, MA (通讯作者)，Drake Ctr, 151 Galbraith Rd, Cincinnati, OH 45216 USA.
EM mary.long@healthall.com
CR BROCK W, 1991, AM SURGEON, V61, P30
   Campbell PE, 2006, J WOUND OSTOMY CONT, V33, P176, DOI 10.1097/00152192-200603000-00014
   CHARIKER M E, 1989, Contemporary Surgery, V34, P59
   Davydov YA, 1986, VESTNIK KHIRURGII, V9, P66
   FLECK CA, 2004, EXTENDED CARE PRODUC, V92, P20
   FOX J, 1978, AM J SURG, V132, P573
   KHOKHOLEVA MA, 1970, TRANSPLANTATION TISS, P179
   Kostiuchenko II, 1986, VESTNIK KHIRURGII, V9, P18
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   Mendonca Derick A, 2006, Int Wound J, V3, P261, DOI 10.1111/j.1742-481X.2006.00266.x
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   NAKAYAMA Y, 1991, ANN PLAS SURG, V26, P499, DOI 10.1097/00000637-199105000-00017
   OKHOTSKY VI, 1973, SOVETSKAYA MEDISTINA, V1, P17
NR 13
TC 3
Z9 4
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAR-APR
PY 2009
VL 36
IS 2
BP 202
EP 211
DI 10.1097/01.WON.0000347664.10217.2e
PG 10
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 423LZ
UT WOS:000264499100011
PM 19287271
DA 2026-07-24
ER

PT J
AU Montecamozzo, G
   Leopaldi, E
   Baratti, C
   Previde, P
   Ferla, F
   Pizzi, M
   Sposato, J
   Pariani, D
   Sartani, A
   Trabucchi, E
AF Montecamozzo, G.
   Leopaldi, E.
   Baratti, C.
   Previde, P.
   Ferla, F.
   Pizzi, M.
   Sposato, J.
   Pariani, D.
   Sartani, A.
   Trabucchi, E.
TI Incarcerated massive incisional hernia: extensive necrosis of the colon
   in a very obese patient. Surgical treatment and vacuum-assisted closure
   therapy: a case report
SO HERNIA
LA English
DT Article
DE Massive incisional hernia; Bowel strangulation; Vacuum-assisted closure;
   Obesity
ID WOUND CONTROL; METALLOPROTEINASES
AB We discuss a diabetic obese patient with an extensive necrosis of the ascending and transverse colon plus segmental necrosis of the small bowel incarcerated in a massive median incisional hernia below the umbilicus. After a blood test and an abdominal CT scan (without contrast dial), the patient underwent an urgent operation. We performed an extended right hemicolectomy, multiple segmental small bowel resections and a terminal ileostomy. The defect of the abdominal wall was treated with vacuum-assisted closure (VAC) therapy with good results.
C1 [Montecamozzo, G.; Leopaldi, E.; Baratti, C.; Previde, P.; Ferla, F.; Pizzi, M.; Sposato, J.; Pariani, D.; Sartani, A.; Trabucchi, E.] AO Luigi Sacco Univ Milano, Chirurg Oncogastrosurg Dept 1, I-20157 Milan, Italy.
C3 University of Milan; Luigi Sacco Hospital
RP Ferla, F (通讯作者)，AO Luigi Sacco Univ Milano, Chirurg Oncogastrosurg Dept 1, Via GH Grassi 74, I-20157 Milan, Italy.
EM fabioferla@hotmail.com
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta PA, 2002, OBSTET GYNECOL, V99, P497, DOI 10.1016/S0029-7844(01)01752-5
   Baynham S A, 1999, Ostomy Wound Manage, V45, P28
   BUCKNALL TE, 1983, ANN ROY COLL SURG, V65, P71
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
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   DIEBEL L, 1992, AM SURGEON, V58, P573
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   MORYKWAS MJ, 1993, ANN M FED AM SOC EXP
   Moses MA, 1996, J CELL BIOCHEM, V60, P379, DOI 10.1002/(SICI)1097-4644(19960301)60:3<379::AID-JCB9>3.3.CO;2-0
   Mutter D., 2000, Hernia, V4, pS3
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
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NR 16
TC 3
Z9 3
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1265-4906
EI 1248-9204
J9 HERNIA
JI Hernia
PD DEC
PY 2008
VL 12
IS 6
BP 641
EP 643
DI 10.1007/s10029-008-0370-4
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 398XA
UT WOS:000262763600015
PM 18427907
DA 2026-07-24
ER

PT J
AU Ogino, A
   Takayama, M
   Takeda, K
   Okada, E
AF Ogino, A.
   Takayama, M.
   Takeda, K.
   Okada, E.
TI EXPERIENCE WITH INTERMITTEN MODE IN NEGATIVE PRESSURE WOUND THERAPY
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Ogino, A.; Takayama, M.; Takeda, K.; Okada, E.] Toho Univ, Dept Plast & Reconstruct Surg, Omori Med Ctr, Ota City, Japan.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD SEP
PY 2021
VL 29
IS 5
MA O6-5
BP A14
EP A15
PG 2
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA UK1FO
UT WOS:000691720500042
DA 2026-07-24
ER

PT J
AU Lemmon, JA
   Ahmad, J
   Ghavami, A
   Bidic, SM
AF Lemmon, Joshua A.
   Ahmad, Jamil
   Ghavami, Ashkan
   Bidic, Sean M.
TI Vacuum-Assisted Closure over an External Fixation Device
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Letter
C1 [Lemmon, Joshua A.; Ahmad, Jamil; Ghavami, Ashkan; Bidic, Sean M.] Univ Texas SW Med Ctr Dallas, Dept Plast Surg, Dallas, TX 75390 USA.
C3 University of Texas System; University of Texas Southwestern Medical
   Center
RP Bidic, SM (通讯作者)，Univ Texas SW Med Ctr Dallas, Dept Plast Surg, 5323 Harry Hines Blvd, Dallas, TX 75390 USA.
EM sean.bidic@utsouthwestern.edu
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
NR 3
TC 11
Z9 11
U1 0
U2 9
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD APR
PY 2008
VL 121
IS 4
BP 234E
EP 235E
DI 10.1097/01.prs.0000305394.80769.8b
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA V13KY
UT WOS:000207666900026
PM 18349619
DA 2026-07-24
ER

PT J
AU Fifes, CE
   Otto, G
   Walker, D
   Turner, T
   Smith, L
AF Fifes, CE
   Otto, G
   Walker, D
   Turner, T
   Smith, L
TI Healing dehisced surgical wounds with negative pressure wound therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
C1 Texas Wound & Lymphedema Ctr, Tomball, TX USA.
   Texas Wound & Lymphedema Ctr, Bryan, TX USA.
   Univ Texas, Hlth Sci Ctr, Houston, TX USA.
C3 University of Texas System; University of Texas Health Science Center
   Houston
RP Fifes, CE (通讯作者)，Texas Wound & Lymphedema Ctr, Tomball, TX USA.
EM caroline.e.fife@uth.tmc.edu
CR Cutting K F, 1994, J Wound Care, V3, P198
   FIFE CE, 2003, NAT VAC ED C LOS ANG
   ROSS C, 2003, UNDERSEA HYPERBAR S, V33
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   Wongworawat MD, 2003, CLIN ORTHOP RELAT R, P45, DOI 10.1097/01.blo.0000084400.53464.02
NR 5
TC 4
Z9 10
U1 0
U2 1
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2004
SU S
BP 28
EP 31
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 817VB
UT WOS:000221203900010
PM 15317243
DA 2026-07-24
ER

PT J
AU Frazee, RC
AF Frazee, Richard C.
TI Closed Negative Pressure Wound Therapy In Reply to Fujita
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Letter
CR Frazee R, 2018, J AM COLL SURGEONS, V226, P507, DOI 10.1016/j.jamcollsurg.2017.12.008
NR 1
TC 0
Z9 0
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD SEP
PY 2018
VL 227
IS 3
BP 388
EP 388
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GR3TD
UT WOS:000442517200011
PM 30146103
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI Negative pressure wound therapy decreases the risk of infections
SO AORN JOURNAL
LA English
DT News Item
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0001-2092
EI 1878-0369
J9 ASSOC OPER ROOM NURS
JI AORN J.
PD AUG
PY 2019
VL 110
IS 2
BP P6
EP P6
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA IM3SU
UT WOS:000477915900004
DA 2026-07-24
ER

PT J
AU Bourke, MH
   Healy, DG
AF Bourke, M. H.
   Healy, D. G.
TI Cost Implications of Negative Pressure Wound Therapy: A Review
SO IRISH JOURNAL OF MEDICAL SCIENCE
LA English
DT Meeting Abstract
C1 [Bourke, M. H.; Healy, D. G.] Mater Misericordiae Univ Hosp, Dept Cardiothorac Surg, Dublin, Ireland.
C3 University College Dublin; Mater Misericordiae University Hospital
NR 0
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER LONDON LTD
PI LONDON
PA 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND
SN 0021-1265
J9 IRISH J MED SCI
JI Irish J. Med. Sci.
PD JUL
PY 2012
VL 181
SU 3
BP S94
EP S95
PG 2
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 985FC
UT WOS:000307247800025
DA 2026-07-24
ER

PT J
AU Fawcett, K
   Gilmore, D
   Harris, N
AF Fawcett, Kristina
   Gilmore, Denise
   Harris, Nicole
TI HARDWARE SALVAGE USING NEGATIVE PRESSURE WOUND THERAPY WITH INSTILLATION
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Gilmore, Denise; Harris, Nicole] Wound Ostomy, Glendale, AZ USA.
EM kristinanp@drberman.me; denise.gilmore@bannerhealth.com;
   nic.r.harris85@gmail.com
CR Lehner B, 2011, INT ORTHOP, V35, P1415, DOI 10.1007/s00264-011-1274-y
NR 1
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2014
VL 41
SU 3
BP S64
EP S64
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA AH2XY
UT WOS:000335986600172
DA 2026-07-24
ER

PT J
AU Molnar, JA
AF Molnar, JA
TI The science behind negative pressure wound therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID SUBATMOSPHERIC PRESSURE
C1 Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27109 USA.
   Wake Forest Univ, Sch Med, Burn Unit, Winston Salem, NC 27109 USA.
C3 Wake Forest University; Wake Forest University
RP Molnar, JA (通讯作者)，Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27109 USA.
EM jmolnar@wfubmc.edu
RI Molnar, Joseph/AEK-5540-2022
CR BENNETT DC, 2002, 47 ANN M MASS APR 17
   Chen KD, 1999, J BIOL CHEM, V274, P18393, DOI 10.1074/jbc.274.26.18393
   GEMEINHARDT K, UNPUB J EQUINE VET S
   JACKSON DM, 1953, BRIT J SURG, V40, P588, DOI 10.1002/bjs.18004016413
   KREMERS L, 2003, PRESENTATION EUROPEA
   MOLNAR J, UNPUB
   Molnar JA, 2000, PLAST RECONSTR SURG, V105, P174, DOI 10.1097/00006534-200001000-00030
   MOLNAR JA, 1997, 13 ANN REG 4 BURN SE
   MOLNAR JA, UNPUB APPL SUBATMOSP
   Morykwas MJ, 1999, J BURN CARE REHABIL, V20, P15, DOI 10.1097/00004630-199901001-00003
   Morykwas MJ, 2002, J TRAUMA, V53, P537, DOI 10.1097/00005373-200209000-00023
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   MORYKWAS MJ, UNPUB EFFECTS SUBATM
   SCHNEIDER AM, PLAST RECONSTR SURG
   WOLFF J, 1918, GAETZ TRANSFORMATION
NR 15
TC 8
Z9 14
U1 1
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2004
SU S
BP 2
EP 5
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 817VB
UT WOS:000221203900002
PM 15317235
DA 2026-07-24
ER

PT J
AU Leiria, M
   Molina, J
   Villagra, F
   Nazra, A
   Oliva, A
   Pagano, C
   Leitner, W
   Petrochelli, L
AF Leiria, M.
   Molina, J.
   Villagra, F.
   Nazra, A.
   Oliva, A.
   Pagano, C.
   Leitner, W.
   Petrochelli, L.
TI Vacuum-Assisted Closure (VAC) in Post-Operative Fistula
SO OBESITY SURGERY
LA English
DT Meeting Abstract
CT 14th World Congress of the
   International-Federation-for-the-Surgery-of-Obesity-and-Metabolic-Disord
   ers
CY AUG 26-29, 2009
CL Paris, FRANCE
SP Int Federat Surg Obes & Metabol Disorders
C1 [Leiria, M.; Molina, J.; Villagra, F.; Nazra, A.; Oliva, A.; Pagano, C.; Leitner, W.; Petrochelli, L.] CITO, Neuquen, Argentina.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0960-8923
J9 OBES SURG
JI Obes. Surg.
PD AUG
PY 2009
VL 19
IS 8
BP 1060
EP 1060
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 472HG
UT WOS:000268120600407
DA 2026-07-24
ER

PT J
AU Netsch, D
   VanWatermulen, L
   Freyberg, J
AF Netsch, Debra
   VanWatermulen, Lisa
   Freyberg, Julie
TI OVERVIEW OF VARIOUS NEGATIVE PRESSURE WOUND THERAPY (NPWT) SYSTEMS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Netsch, Debra; VanWatermulen, Lisa; Freyberg, Julie] Mankato Clin, Mankato, MN USA.
EM debnetsch@charter.net; LisaV@mankato-clinic.com;
   juliefr@mankato-clinic.com
CR Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
NR 1
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2011
VL 38
IS 3
SU S
MA 5235
BP S42
EP S42
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 772LI
UT WOS:000291235000115
DA 2026-07-24
ER

PT J
AU Davis, JM
AF Davis, JM
TI Combining wound debridement modalities with negative pressure wound
   therapy
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA.
C3 University of Texas System; UTMD Anderson Cancer Center
EM jmdavis@mdanderson.org
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2006
VL 33
IS 3
SU 1
BP S11
EP S12
PG 2
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 047AN
UT WOS:000237852300022
DA 2026-07-24
ER

PT J
AU Murase, C
   Kono, M
   Nakanaga, K
   Md, NI
   Akiyama, M
AF Murase, Chiaki
   Kono, Michihiro
   Nakanaga, Kazue
   Md, Norihisa Ishii
   Akiyama, Masashi
TI Buruli Ulcer Successfully Treated With Negative-Pressure Wound Therapy
SO JAMA DERMATOLOGY
LA English
DT Letter
C1 [Murase, Chiaki; Kono, Michihiro; Akiyama, Masashi] Nagoya Univ, Grad Sch Med, Dept Dermatol, Nagoya, Aichi 4668550, Japan.
   [Nakanaga, Kazue; Md, Norihisa Ishii] Natl Inst Infect Dis, Leprosy Res Ctr, Tokyo, Japan.
C3 Nagoya University; Japan Institute for Health Security (JIHS); National
   Institute of Infectious Diseases (NIID)
RP Kono, M (通讯作者)，Nagoya Univ, Grad Sch Med, Dept Dermatol, Showa Ku, 65 Tsurumai Cho, Nagoya, Aichi 4668550, Japan.
EM miro@med.nagoya-u.ac.jp
RI Akiyama, Masashi/ITT-0847-2023; Kono, Michihiro/I-1238-2012
OI Akiyama, Masashi/0000-0001-5863-9315; 
CR Nakanaga K, 2007, J CLIN MICROBIOL, V45, P3840, DOI 10.1128/JCM.01041-07
   O'Brien DP, 2014, LANCET INFECT DIS, V14, P435, DOI 10.1016/S1473-3099(13)70201-9
   Saaiq M, 2010, JCPSP-J COLL PHYSICI, V20, P675, DOI 04.2010/JCPSP.675679
   WHO, 2010, WORKING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES: FIRST WHO REPORT ON NEGLECTED TROPICAL DISEASES, P1
   WHO, 2014, LAB DIAGN BUR ULC MA
   World Health Organization, 2012, Treatment of Mycobacteriumulcerans disease (Buruli Ulcer): guidance for health workers
NR 6
TC 9
Z9 11
U1 0
U2 3
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 2168-6068
EI 2168-6084
J9 JAMA DERMATOL
JI JAMA Dermatol.
PD OCT
PY 2015
VL 151
IS 10
BP 1137
EP 1139
DI 10.1001/jamadermatol.2015.1567
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA CT6XF
UT WOS:000362955700025
PM 26106826
OA Bronze
DA 2026-07-24
ER

PT J
AU Lee, HJ
   Lee, H
AF Lee, Hyun Jik
   Lee, Hyuk
TI Endoscopic Vacuum-assisted Closure With Sponge for Esophagotracheal
   Fistula After Esophagectomy
SO SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES
LA English
DT Article
DE endoscopic vacuum-assisted closure with sponge; esophagotracheal
   fistula; esophagectomy
ID INTESTINAL ANASTOMOTIC LEAKS; EXPERIENCE; MANAGEMENT; SURGERY
AB We experienced a case of endoscopic vacuum-assisted closure with sponge for esophagotracheal fistula diagnosed after esophagectomy due to squamous cell esophageal cancer. The patient, who had undergone a robotic-assisted thoracoscopic esophagectomy and esophageal reconstruction of the stomach, was referred for the management of esophagotracheal fistula. Diagnostic esophagogastroduodenoscopy and imaging studies were performed, and they indicated anastomotic leakage with esophagotracheal fistula. The patient was treated by the endoscopic placement of full-covered self-expanding metal stents, but the fistula persisted. Then, we applied a size-adjusted sponge endoscopically with continuous suction by a vacuum system in the fistula lesion. Complete closure was achieved without any procedure-related complications. After 40 days, symptomatic esophageal stricture was detected and treated successfully with endoscopic balloon dilation. Endoscopic vacuum-assisted closure with a sponge might be an adequate alternative treatment option for esophageal stenting for esophagotracheal fistula after esophagectomy.
C1 [Lee, Hyun Jik] Minimally Invas Image Guided Surg Inst, IHU, Strasbourg, France.
   [Lee, Hyuk] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med,Div Gastroenterol, Seoul 135710, South Korea.
C3 Sungkyunkwan University (SKKU); Samsung Medical Center
RP Lee, H (通讯作者)，Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med,Div Gastroenterol, 50 Irwon Dong, Seoul 135710, South Korea.
EM leehyuk@skku.edu
CR Babor Richard, 2009, Surg Laparosc Endosc Percutan Tech, V19, pe1, DOI 10.1097/SLE.0b013e318196c706
   Bludau M, 2014, SURG ENDOSC, V28, P896, DOI 10.1007/s00464-013-3244-5
   Doniec JM, 2003, ENDOSCOPY, V35, P652
   Faller J, 1996, SURG TODAY, V26, P368, DOI 10.1007/BF00311610
   Loske G, 2009, GASTROINTEST ENDOSC, V69, P601, DOI 10.1016/j.gie.2008.06.058
   Miller JD, 1997, J SURG ONCOL, V65, P20, DOI 10.1002/(SICI)1096-9098(199705)65:1<20::AID-JSO4>3.0.CO;2-Q
   Vallböhmer D, 2010, DIS ESOPHAGUS, V23, P185, DOI 10.1111/j.1442-2050.2009.01017.x
   van Koperen PJ, 2009, SURG ENDOSC, V23, P1379, DOI 10.1007/s00464-008-0186-4
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
NR 9
TC 13
Z9 13
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1530-4515
EI 1534-4908
J9 SURG LAPARO ENDO PER
JI Surg. Laparosc. Endosc. Pct. Tech.
PD APR
PY 2015
VL 25
IS 2
BP E76
EP E77
DI 10.1097/SLE.0000000000000143
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CF0JV
UT WOS:000352230800008
PM 25799256
DA 2026-07-24
ER

PT J
AU Canavese, F
   Krajbich, JI
   Kuang, AA
AF Canavese, Federico
   Krajbich, Joseph I.
   Kuang, Anna A.
TI Application of the vacuum-assisted closure in pediatric patients with
   orthopedic sequelae of meningococcemia: report of a case successfully
   treated
SO JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B
LA English
DT Article
DE meningococcemia; soft tissue loss; vacuum-assisted closure therapy;
   wound healing
ID WOUND MANAGEMENT; SOFT; EXPERIENCE; SEPTICEMIA
AB Patients who survive the initial acute phase of fulminant meningococcemia are at an increased risk for serious complications as a result of poor tissue perfusion. It is rare that early surgical intervention is required, as it is relatively difficult to determine the degree of tissue loss early on. Once the patient is stable, debridement of all necrotic tissue is essential and may necessitate extensive removal of skin, subcutaneous tissue, and muscle. Widespread use of the vacuum-assisted closure for complex soft tissue injuries has generally showed accelerated wound healing compared with traditional methods. We report a new possible application of the vacuum-assisted closure system in very young patients with loss of tissue as a result of purpura fulminans secondary to meningococcemia. J Pediatr Orthop B 18:388-391 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
C1 [Canavese, Federico; Krajbich, Joseph I.; Kuang, Anna A.] Shriners Hosp Crippled Children, Portland, OR 97239 USA.
RP Canavese, F (通讯作者)，Shriners Hosp Crippled Children, 3101 SW Sam Jackson Pk Rd, Portland, OR 97239 USA.
EM canavese_federico@yahoo.fr
OI CANAVESE, Federico/0000-0002-6114-5372
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bache CE, 2006, J PEDIATR ORTHOPED, V26, P135, DOI 10.1097/01.bpo.0000187991.71645.e7
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   Bütter A, 2006, J PEDIATR SURG, V41, P940, DOI 10.1016/j.jpedsurg.2006.01.061
   Canavese F, 2008, J BONE JOINT SURG BR, V90B, P377, DOI 10.1302/0301-620X.90B3.19890
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Contractor D, 2008, J ORTHOP TRAUMA, V22, pS167, DOI 10.1097/BOT.0b013e318188e295
   HAMDY RC, 1993, J PEDIATR ORTHOPED, V13, P447, DOI 10.1097/01241398-199307000-00006
   KOLLER A, 1991, AM J PHYSIOL, V62, pH868
   Milonovich Lisa M, 2007, J Pediatr Health Care, V21, P75, DOI 10.1016/j.pedhc.2006.05.001
   Mooney JF, 2000, CLIN ORTHOP RELAT R, P26
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Muangman P, 2006, ANN PLAS SURG, V57, P199, DOI 10.1097/01.sap.0000218636.61803.d6
   O'Connor J, 2005, ANN THORAC SURG, V79, P1196, DOI 10.1016/j.athoracsur.2004.09.041
   Penington AJ, 2007, ANN PLAS SURG, V58, P308, DOI 10.1097/01.sap.0000237642.46000.e6
   URSCHEL JD, 1988, BRIT J PLAST SURG, V41, P182, DOI 10.1016/0007-1226(88)90049-5
NR 16
TC 4
Z9 5
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1060-152X
J9 J PEDIATR ORTHOP B
JI J. Pediatr. Orthop.-Part B
PD NOV
PY 2009
VL 18
IS 6
BP 388
EP 391
DI 10.1097/BPB.0b013e32832d83c9
PG 4
WC Orthopedics; Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Pediatrics
GA 506HI
UT WOS:000270765400022
PM 19620896
DA 2026-07-24
ER

PT J
AU McGuinness, JG
   Winter, DC
   O'Connell, PR
AF McGuinness, JG
   Winter, DC
   O'Connell, PR
TI Vacuum-assisted closure of a complex pilonidal sinus
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article
DE pilonidal sinus; closure; vacuum-assisted
ID SUBATMOSPHERIC PRESSURE; WOUND CONTROL; COMPLICATIONS
AB INTRODUCTION: The annual incidence of pilonidal sinus is approximately 26 per 100,000, of which complex pilonidal sinuses are the minority. Many different approaches have been described for managing simple cases. Treatment options for complex pilonidal sinus include excision with healing by secondary intention or plastic surgical procedures to obliterate the defect. Recently, vacuum-assisted closure has been used by plastic surgeons to facilitate healing of chronic or complicated,wounds with particular success in treating pressure wounds overlying the sacrum. METHODS: A patient with a complex pilonidal sinus was managed with excision and vacuum-assisted closure. RESULTS: A large tissue defect after radical excision healed relatively quickly when the subatmospheric pressure dressing was applied. The patient was discharged with the vacuum pump and change of dressings for alternate days. CONCLUSION: Vacuum-assisted closure of a complex pilonidal sinus shortened the length of hospital stay and the need for further surgery and provided a cosmetically acceptable result.
C1 Univ Coll Dublin, Mater Misericordiae Hosp, Dept Surg, Dublin 7, Ireland.
C3 University College Dublin; Mater Misericordiae University Hospital
RP O'Connell, PR (通讯作者)，Univ Coll Dublin, Mater Misericordiae Hosp, Dept Surg, Dublin 7, Ireland.
RI O'Connell, P. Ronan/H-6583-2019
OI O'Connell, P. Ronan/0000-0002-1846-5629
CR ALLENMERSH TG, 1990, BRIT J SURG, V77, P123, DOI 10.1002/bjs.1800770203
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Berger A, 1995, ANN CHIR, V49, P889
   Cervelli V, 1997, Minerva Chir, V52, P659
   da Silva JH, 2000, DIS COLON RECTUM, V43, P1146
   Destito C, 1997, G Chir, V18, P441
   Fabian TS, 2000, AM SURGEON, V66, P1136
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   Greer SE, 1999, ANN PLAS SURG, V43, P551, DOI 10.1097/00000637-199911000-00016
   Greer SE, 2001, ANN THORAC SURG, V71, P1038, DOI 10.1016/S0003-4975(00)02431-0
   GREER SE, ANN PLAST SURG, V45, P332
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   Morykwas MJ, 1999, J BURN CARE REHABIL, V20, P15, DOI 10.1097/00004630-199901001-00003
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   SURRELL JA, 1994, SURG CLIN N AM, V74, P1309
NR 15
TC 48
Z9 60
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD FEB
PY 2003
VL 46
IS 2
BP 274
EP 276
DI 10.1007/s10350-004-6535-z
PG 3
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 646KB
UT WOS:000181033200019
PM 12576904
DA 2026-07-24
ER

PT J
AU Wagner, A
AF Wagner, Andreas
TI Use of Vacuum-Assisted Closure Therapy for the Conditioning of
   Soft-Tissue Defects
SO OPERATIVE ORTHOPADIE UND TRAUMATOLOGIE
LA German
DT Article
DE Vacuum sealing technique; Vacuum-assisted closure; VAC therapy
AB The Problem
   Acute or chronic wounds requiring temporary wound coverage and closure.
   Soft-tissue defects unsuitable for any type of wound closure.
   Soft-tissue defects associated with infection.
   The Solution
   Temporary or definite wound closure according to a general concept for treatment of acute or chronic wounds. Support of wound healing through enhanced cell proliferation and formation of granulation tissue. Improvement of local blood circulation and eradication of infection.
   Surgical Technique
   Surgical debridement.
   Temporary wound closure with vacuum-assisted closure therapy.
   Second look with change of vacuum-assisted closure systems, irrigation and debridement procedures.
   Definitive wound closure through
   vacuum-aided wound reduction and secondary suture or
   mesh grafting or
   debridement and flap coverage.
   Results
   Embedded in the general concept of treatment algorithm for acute or chronic wounds, vacuum-assisted wound closure is part of the therapy. Vacuum therapy facilitates direct wound closure or improves wound conditioning to assist further surgical procedures.
C1 Rudolf Elle gGmbH, Waldkrankenhaus, Lehrstuhl Orthopadie, D-07607 Eisenberg, Germany.
RP Wagner, A (通讯作者)，Rudolf Elle gGmbH, Waldkrankenhaus, Lehrstuhl Orthopadie, Klosterlausnitzer Str 81, D-07607 Eisenberg, Germany.
EM XAndreasWagnerX@aol.com
CR FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Fleischmann W, 1997, UNFALLCHIRURG, V100, P301, DOI 10.1007/s001130050123
   Holle G, 2007, UNFALLCHIRURG, V110, P490, DOI 10.1007/s00113-007-1267-x
   *IQWIG, 2006, 0403 IQWIG
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
NR 6
TC 1
Z9 2
U1 0
U2 2
PU URBAN & VOGEL
PI MUNICH
PA NEUMARKTER STRASSE 43, D-81673 MUNICH, GERMANY
SN 0934-6694
J9 OPER ORTHOPADE TRAUM
JI Oper. Orthopade Traumatol.
PD DEC
PY 2008
VL 20
IS 6
BP 525
EP 533
DI 10.1007/s00064-008-1508-3
PG 9
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 403FB
UT WOS:000263067400009
PM 19137399
DA 2026-07-24
ER

PT J
AU Schwien, T
   Gilbert, J
   Lang, C
AF Schwien, T
   Gilbert, J
   Lang, C
TI Pressure ulcer prevalence and the role of negative pressure wound
   therapy in home health quality outcomes
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE home health; pressure ulcer prevalence; outcomes; negative pressure
   wound therapy
ID CLOSURE
AB Home health agencies, challenged to demonstrate quality while containing costs, are motivated to find best practices for managing patient and wound care. The effects of different wound therapies on frequency of hospitalization and emergent care, two prominent quality measures, have not been studied. A retrospective study was conducted to determine the prevalence of Stage III and Stage IV pressure ulcers in the home health population and to quantify the impact of negative pressure wound therapy in reducing acute care hospitalizations and emergent care in general, and wound infection or deteriorating wound status in particular. Data from 1.94 million OASIS start-of-care assessments in 2003 and 2004 were evaluated to estimate pressure ulcer prevalence and a retrospective matched group analysis compared patients using (n = 60) and not using (n = 2,288) negative pressure wound therapy. In 2003, 6.9% and in 2004, 7% of patients had pressure ulcers at start of care. Of these, 23% were Stage III or Stage IV and 31% were "not healing." In the matched analysis group, it was found that compared to comparison group patients, those receiving negative pressure wound therapy experienced lower rates of hospitalization (35% versus.48%, P < .05), hospitalization due to wound problems (5% versus 14%, P < .01), and emergent care for wound problems (0% versus 8%, P = .01). To offset potential limitations in generalizability and increase practical application of these results, further research is needed with a larger, nationally representative sample to compare other quality outcomes as well as the cost of providing negative pressure wound therapy to other specific wound care modalities.
C1 Outcome Concept Syst Inc, Data Consulting, Seattle, WA 98112 USA.
   Outcome Concept Syst Inc, Data & Prod Serv, Seattle, WA 98112 USA.
RP Schwien, T (通讯作者)，Outcome Concept Syst Inc, Data Consulting, 1818 E Mercer St, Seattle, WA 98112 USA.
EM tinsch@ocsys.com
CR Barak A, 2003, J CAREER ASSESSMENT, V11, P3, DOI 10.1177/106907202237457
   *DEP HLTH HUM SERV, 2002, FIN REP HOM HLTH OUT
   *DEP HLTH HUM SERV, 2005, OUTC BAS QUAL IMPR O
   *DEP HLTH HUM SERV, 2005, OUTC BAS QUAL MON RE
   Department of Health and Human Services Healthcare Financing Administration, 2001, QUAL MON US CAS MIX
   Ford CN, 2002, ANN PLAS SURG, V49, P55, DOI 10.1097/00000637-200207000-00009
   Isago T, 2003, J DERMATOL, V30, P299, DOI 10.1111/j.1346-8138.2003.tb00391.x
   Kinsella Audrey, 2002, Home Healthc Nurse, V20, P457, DOI 10.1097/00004045-200207000-00012
   Kobza L, 2000, Ostomy Wound Manage, V46, P48
   Langemo Diane, 2003, Home Healthc Nurse, V21, P309, DOI 10.1097/00004045-200305000-00007
   Madigan EA, 2003, RES NURS HEALTH, V26, P273, DOI 10.1002/nur.10094
   Metzger Stephanie, 2004, Home Healthc Nurse, V22, P586, DOI 10.1097/00004045-200409000-00003
   Ovington L G, 2001, Home Healthc Nurse, V19, P477, DOI 10.1097/00004045-200108000-00007
   Page Jeffrey C, 2004, Adv Skin Wound Care, V17, P354, DOI 10.1097/00129334-200409000-00015
   Pieper B, 1999, Adv Wound Care, V12, P117
   Wanner MB, 2003, SCAND J PLAST RECONS, V37, P28
NR 16
TC 55
Z9 65
U1 1
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD SEP
PY 2005
VL 51
IS 9
BP 47
EP +
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 000QZ
UT WOS:000234478700010
PM 16230764
DA 2026-07-24
ER

PT J
AU Mizutani, T
   Yagi, N
   Sakai, S
   Sakamoto, Y
   Ochiai, H
AF Mizutani, T.
   Yagi, N.
   Sakai, S.
   Sakamoto, Y.
   Ochiai, H.
TI OUR THERAPEUTIC APPROACH WITH VACUUM ASSISTED CLOSURE (VAC) SYSTEM
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Mizutani, T.; Yagi, N.; Ochiai, H.] Natl Hosp Org, Tokyo Med Ctr, Tokyo, Japan.
   [Sakai, S.; Sakamoto, Y.] Keio Univ, Sch Med, Tokyo 108, Japan.
C3 Keio University
RI /ABC-3869-2020
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JAN
PY 2014
VL 22
IS 1
BP A15
EP A15
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 284DL
UT WOS:000329296200059
DA 2026-07-24
ER

PT J
AU Adegboye, O
   Pillay, K
   Adams, S
AF Adegboye, Oluwatobi
   Pillay, Kamlen
   Adams, Saleigh
TI Acellular Dermal Matrices in Reconstructive Pediatric Complex Lower Limb
   Trauma: An Observational Study
SO JOURNAL OF TRAUMA NURSING
LA English
DT Article
DE Acellular dermal matrices (ADMs); Lower limb trauma; Negative pressure
   wound therapy (NPWTs); Observational study; Pediatric trauma;
   Retrospective study; Trauma complications
ID PRESSURE WOUND THERAPY; MANAGEMENT; COVERAGE; FLAPS
AB BACKGROUND:Contemporary research has shown that acellular dermal matrices can benefit adult lower extremity traumatic injuries; however, its use in children has not been explored.OBJECTIVE:This study aims to explore the use of acellular dermal matrices in pediatric complex lower extremity trauma.METHODS:This single-center retrospective observational cohort study of children with complex lower extremity trauma treated with Pelnac (TM), commercial acellular dermal matrices, was conducted at a tertiary hospital in South Africa from 2010 to 2017. Demographic and clinical data were collected from medical records. The primary outcome was the rate and type of acellular dermal matrices-related complications. Secondary outcomes included the usage of negative pressure wound therapy.RESULTS:A total of 54 children were studied; 30 (55%) were male, and the median age was six. Forty-five children healed without complications, while nine experienced complications - four acute and five chronic. Four patients had complete loss of acellular dermal matrices, and three developed acute infections. More than 30 days post-acellular dermal matrices application, five patients had hypertrophic scarring, four had joint contractures, and two had non-healing wounds. All patients who healed without complication received negative pressure wound therapy (n = 45), while those who did not (n = 5) developed complications. Three of the five patients without negative pressure wound therapy had acute acellular dermal matrices loss, compared to only one of the 49 patients who received negative pressure wound therapy.CONCLUSION:Our findings suggest that acellular dermal matrices may be an effective and safe reconstructive adjunct or alternative when used with negative pressure wound therapy.
C1 [Adegboye, Oluwatobi] Anglia Ruskin Univ, Fac Hlth Educ Med & Social Care, St Andrews Anglia Ruskin StAAR Res Grp, Chelmsford, England.
   [Pillay, Kamlen; Adams, Saleigh] Red Cross War Mem Childrens Hosp, Div Plast & Reconstruct Surg, Cape Town, South Africa.
   [Pillay, Kamlen; Adams, Saleigh] Univ Cape Town, Groote Schuur Hosp, Div Plast & Reconstruct Surg, Cape Town, South Africa.
C3 Anglia Ruskin University; University of Cape Town
RP Adegboye, O (通讯作者)，Broomfield Hosp, St Andrews Anglia Ruskin Res Grp StAAR, Chelmsford CM1 7ET, England.; Adegboye, O (通讯作者)，Broomfield Hosp, St Andrews Ctr Plast Surg & Burns, Chelmsford CM1 7ET, England.
EM oa34@aru.ac.uk; drpillay@scinmed.com; saleigh.adams@uct.ac.za
RI Ada, Saleigh/AGI-8895-2022; Adegboye, Oluwatobi/KOC-8212-2024
OI Ada, Saleigh/0000-0002-0552-9400; Adegboye,
   Oluwatobi/0000-0003-1659-9444
CR Adams WP, 2018, AESTHET SURG J, V38, P502, DOI 10.1093/asj/sjy022
   Ahn J, 2022, J WOUND CARE, V31, P310, DOI 10.12968/jowc.2022.31.4.310
   Alam HB, 2015, CURR TRAUMA REP, V1, P61, DOI 10.1007/s40719-014-0007-2
   Ali RA, 2024, PRS-GLOB OPEN, V12, DOI 10.1097/GOX.0000000000005673
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   Butowicz CM, 2017, ADV WOUND CARE, V6, P269, DOI 10.1089/wound.2016.0714
   Dadlani Shashi, 2021, Int J Dent, V2021, P1652032, DOI [10.1155/2021/1652032, 10.1155/2021/1652032]
   di Summa PG, 2013, ANN PLAS SURG, V71, P461, DOI 10.1097/SAP.0b013e3182503ad9
   Diller RB, 2022, BIOMIMETICS-BASEL, V7, DOI 10.3390/biomimetics7030087
   Duncan D I, 2001, Aesthet Surg J, V21, P81, DOI 10.1067/maj.2001.113438
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   Haney NM, 2021, SEX MED REV, V9, P488, DOI 10.1016/j.sxmr.2020.07.003
   HEIMBACH D, 1988, ANN SURG, V208, P313, DOI 10.1097/00000658-198809000-00008
   Hsu KF, 2021, MEDICINE, V100, DOI 10.1097/MD.0000000000025395
   Jackson SR, 2019, J BURN CARE RES, V40, P251, DOI 10.1093/jbcr/irz006
   Jorgensen AM, 2023, J BURN CARE RES, V44, pS33, DOI 10.1093/jbcr/irac126
   Kim MJ, 2022, FRONT MATER, V9, DOI 10.3389/fmats.2022.1013245
   Kim YJ, 2024, EUR J ORTHOP SURG TR, V34, P1971, DOI 10.1007/s00590-024-03888-9
   Kim YH, 2019, J WOUND CARE, V28, pS12, DOI 10.12968/jowc.2019.28.Sup4.S12
   Kirsner RS, 2015, INT WOUND J, V12, P646, DOI 10.1111/iwj.12185
   Koul Ashok Raj, 2013, Indian J Plast Surg, V46, P247, DOI 10.4103/0970-0358.118600
   Larsen AK, 2020, ANN BREAST SURG, V4, P5, DOI [10.21037/abs.2020.01.01, DOI 10.21037/ABS.2020.01.01]
   Lewis RE, 2019, AM SURGEON, V85, P1056
   Li GC, 2023, BMC SURG, V23, DOI 10.1186/s12893-022-01871-x
   Liu JX, 2017, CELL DEATH DIS, V8, DOI 10.1038/cddis.2017.564
   Lumley ES, 2021, EUR J PLAST SURG, V44, P679, DOI 10.1007/s00238-021-01803-7
   Macadam SA, 2012, CAN J PLAST SURG, V20, P75, DOI 10.1177/229255031202000201
   Messner J, 2020, INJURY, V51, P1576, DOI 10.1016/j.injury.2020.03.059
   Mohammadyari F, 2023, FRONT TRANSPLANT, V2, DOI [10.3389/frtra.2023.1133806, 10.3389/frtra.2023.1133806]
   Ndung'u A, 2019, AFR J EMERG MED, V9, pS47, DOI 10.1016/j.afjem.2018.12.004
   Nguyen DQA, 2010, BURNS, V36, P23, DOI 10.1016/j.burns.2009.07.011
   Nordmeyer M, 2016, INT WOUND J, V13, P1176, DOI 10.1111/iwj.12436
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   Quaba O, 2006, SEMIN PLAST SURG, V20, P103, DOI DOI 10.1055/S-2006-941717
   Salzano G, 2023, J CLIN MED, V12, DOI 10.3390/jcm12113700
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   van Zuijlen PPM, 2015, BURNS TRAUMA, V3, DOI 10.1186/s41038-015-0017-5
NR 43
TC 0
Z9 1
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1078-7496
EI 1932-3883
J9 J TRAUMA NURS
JI J. Trauma Nurs.
PD JAN-FEB
PY 2025
VL 32
IS 1
BP 23
EP 29
DI 10.1097/JTN.0000000000000829
PG 7
WC Critical Care Medicine; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC General & Internal Medicine; Nursing
GA U3L5A
UT WOS:001410848700003
PM 39879269
DA 2026-07-24
ER

PT J
AU Leitao, MM Jr
   Zhou, QC
   Schiavone, MB
   Cowan, RA
   Smith, ES
   Iasonos, A
   Veith, M
   Rafizadeh, M
   Curran, K
   Ramesh, B
   Chi, DS
   Sonoda, Y
   Brown, AK
   Cosin, JA
   Abu-Rustum, NR
   Martino, MA
   Mueller, JJ
   Roche, KL
   Jewell, EL
   Broach, V
   Lambrou, NC
   Diaz, JP
   Zivanovic, O
AF Leitao, Mario M., Jr.
   Zhou, Qin C.
   Schiavone, Maria B.
   Cowan, Renee A.
   Smith, Evan S.
   Iasonos, Alexia
   Veith, Mitchell
   Rafizadeh, Michael
   Curran, Katherine
   Ramesh, Bhavani
   Chi, Dennis S.
   Sonoda, Yukio
   Brown, Amy K.
   Cosin, Jonathan A.
   Abu-Rustum, Nadeem R.
   Martino, Martin A.
   Mueller, Jennifer J.
   Roche, Kara Long
   Jewell, Elizabeth L.
   Broach, Vance
   Lambrou, Nicholas C.
   Diaz, John P.
   Zivanovic, Oliver
TI Prophylactic Negative Pressure Wound Therapy After Laparotomy for
   Gynecologic Surgery A Randomized Controlled Trial
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Article; Proceedings Paper
CT 51st Virtual Annual Meeting of the Society-of-Gynecologic-Oncology on
   Women's Cancer
CY MAR 27-31, 2020
CL ELECTR NETWORK
SP Soc Gynecol Oncol
ID SURGICAL-SITE INFECTION; OBESE WOMEN; CANCER; IMPACT; COSTS; PREDICTORS
AB OBJECTIVE: To estimate the effectiveness of prophylactic negative pressure wound therapy in patients undergoing laparotomy for gynecologic surgery.
   METHODS: We conducted a randomized controlled trial. Eligible, consenting patients, regardless of body mass index (BMI), who were undergoing laparotomy for presumed gynecologic malignancy were randomly allocated to standard gauze or negative pressure wound therapy. Patients with BMIs of 40 or greater and benign disease also were eligible. Randomization, stratified by BMI, occurred after skin closure. The primary outcome was wound complication within 30 (+/- 5) days of surgery. A sample size of 343 per group (N=686) was planned.
   RESULTS: From March 1, 2016, to August 20, 2019, we identified 663 potential patients; 289 were randomized to negative pressure wound therapy (254 evaluable participants) and 294 to standard gauze (251 evaluable participants), for a total of 505 evaluable patients. The median age of the entire cohort was 61 years (range 20-87). Four hundred ninety-five patients (98%) underwent laparotomy for malignancy. The trial was eventually stopped for futility after an interim analysis of 444 patients. The rate of wound complications was 17.3% in the negative pressure wound therapy (NPWT) group and 16.3% in the gauze group, absolute risk difference 1% (90% CI -4.5 to 6.5%; P =.77). Adjusted odds ratio controlling for estimated blood loss and diabetes was 0.99 (90% CI 0.621.60). Skin blistering occurred in 33 patients (13%) in the NPWT group and in three patients (1.2%) in the gauze group (P<.001).
   CONCLUSION: Negative pressure wound therapy after laparotomy for gynecologic surgery did not lower the wound complication rate but did increase skin blistering.
C1 Mem Sloan Kettering Canc Ctr, Dept Biostat & Epidemiol, Weill Cornell Med Coll,Dept Surg,Gynecol Serv, Dept Obstet & Gynecol,Mem Sloan Kettering Canc Ct, 1275 York Ave, New York, NY 10021 USA.
   Hartford Healthcare Canc Inst, Div Gynecol Oncol, Hartford, CT USA.
   Lehigh Valley Canc Inst, Allentown, PA USA.
   Miami Canc Inst, Miami, FL USA.
C3 Memorial Sloan Kettering Cancer Center; Cornell University; Weill
   Cornell Medicine
RP Leitao, MM Jr (通讯作者)，Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, New York, NY 10021 USA.
EM leitaom@mskcc.org
RI Zivanovic, Oliver/AAK-9955-2021; zhou, qin/ISV-5657-2023
FU Stryker/Novadaq; Olympus; GRAIL; Merck; AstraZeneca; National Cancer
   Institute [P30CA008748] Funding Source: NIH RePORTER
FX Dr. Leitao reports personal fees from Intuitive Surgical, Inc. and
   JNJ/Ethicon; Dr. Jewell reports personal fees from Covidien/Medtronic;
   Dr. Chi reports personal fees from Bovie Medical Co., Verthermia Inc.
   (now Apyx Medical Corp.), C Surgeries, and Biom `Up, as well as previous
   stock ownership in Intuitive Surgical, Inc. and TransEnterix, Inc. Dr.
   Abu-Rustum reports grants from Stryker/Novadaq, Olympus, and GRAIL. Dr.
   Iasonos reports personal fees from Mylan. Dr. Martino is a patient
   safety consultant for Intuitive, Surgical, Inc., JNJ, Medtronic, and
   CMR, as well as an education speaker for GlaxoSmithKline and a peer
   reviewer for UpToDate. Dr. Lambrou is a consultant for Ethicon and
   Intuitive Surgical, Inc. Dr. Diaz is a speaker and has research grant
   support from Merck and AstraZeneca, and he is a consultant for ConMed.
   Dr. Cosin is a consultant for Medtronic. The other authors did not
   report any potential conflicts of interest.
CR Bakkum-Gamez JN, 2013, GYNECOL ONCOL, V130, P100, DOI 10.1016/j.ygyno.2013.03.022
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   Costa ML, 2020, JAMA-J AM MED ASSOC, V323, P519, DOI 10.1001/jama.2020.0059
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   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
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NR 21
TC 18
Z9 24
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0029-7844
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD FEB
PY 2021
VL 137
IS 2
BP 334
EP 341
DI 10.1097/AOG.0000000000004243
PG 8
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Obstetrics & Gynecology
GA SL0UE
UT WOS:000656630800023
PM 33416292
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Williams, DV
AF Williams, DV
TI An interactive economic model for vacuum assisted closure therapy
SO VALUE IN HEALTH
LA English
DT Meeting Abstract
C1 Milliman, Windsor, CT USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 1098-3015
J9 VALUE HEALTH
JI Value Health
PD MAY-JUN
PY 2006
VL 9
IS 3
BP A58
EP A58
DI 10.1016/S1098-3015(10)64483-X
PG 1
WC Economics; Health Care Sciences & Services; Health Policy & Services
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Business & Economics; Health Care Sciences & Services
GA 038MC
UT WOS:000237224200180
OA Bronze
DA 2026-07-24
ER

PT J
AU Rigel, A
   Rothemich, R
   Botham, P
   Ross, J
   Pellegrini, E
   Brunette, G
AF Rigel, Allyson
   Rothemich, Rebecca
   Botham, Phill
   Ross, Julie
   Pellegrini, Emily
   Brunette, Glenda
TI MANAGEMENT OF FLAP HARVEST SITES WITH NEGATIVE PRESSURE WOUND THERAPY
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
EM dodsona@musc.edu; ROTHEMIC@MUSC.EDU; BOTHAM@MUSC.EDU; rossje@musc.edu;
   Ekpellegrini@gmail.com; brunette@musc.edu
CR Schmedes GW, 2012, OTOLARYNG HEAD NECK, V147, P1049, DOI 10.1177/0194599812459015
NR 1
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2016
VL 43
IS 3
SU S
MA PI16-002
BP S29
EP S29
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA DR7WM
UT WOS:000380110400069
DA 2026-07-24
ER

PT J
AU Close, M
   Cooper, C
AF Close, Malinda
   Cooper, Cassie
TI MANAGING AN OPEN TRACHEOSTOMY SITE WITH NEGATIVE PRESSURE WOUND THERAPY
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Close, Malinda; Cooper, Cassie] Wound Ostomy, Salem, OR USA.
EM Malinda.Close@salemhealth.org; cassie.cooper@salemhealth.org
CR Bode Kenneth, 2011, J Surg Orthop Adv, V20, P44
   Johnston JJ, 2013, NEW ZEAL MED J, V126, P74
   Philippe G, 2012, CRIT CARE RES PRACT, V2012, DOI 10.1155/2012/252719
NR 3
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2018
VL 45
SU 3
MA ePI95
BP S70
EP S70
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA VJ3IV
UT WOS:000579808400166
DA 2026-07-24
ER

PT J
AU Rand, BC
   Wenke, JC
AF Rand, B. C.
   Wenke, Joseph C.
TI Is Local Antibiotic Delivery Compatible with Negative Pressure Wound
   Therapy?
SO BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
CT International Surgical Congress of the
   Association-of-Surgeons-of-Great-Britain-and-Ireland
CY APR 22-24, 2015
CL Manchester, ENGLAND
SP Assoc Surg Great Britain & Ireland
C1 [Rand, B. C.] Acad Dept Mil Surg & Trauma, San Antonio, TX USA.
   [Wenke, Joseph C.] US Army Inst Surg Res Extrem Trauma, San Antonio, TX USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0007-1323
EI 1365-2168
J9 BRIT J SURG
JI Br. J. Surg.
PD SEP
PY 2015
VL 102
SU 7
SI SI
MA 1018
BP 194
EP 194
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA DA9LN
UT WOS:000368130400657
DA 2026-07-24
ER

PT J
AU Doughty, D
AF Doughty, Dorothy
TI WOC Nurse Wound Consult Negative Pressure Wound Therapy
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
ID HERNIA REPAIR
C1 Emory Univ, WOCNEC, Atlanta, GA 30322 USA.
C3 Emory University
RP Doughty, D (通讯作者)，Emory Univ, WOCNEC, Atlanta, GA 30322 USA.
EM ddought@emory.edu
CR Candage R, 2008, SURGERY, V144, P703, DOI 10.1016/j.surg.2008.06.018
   Frantz R.A., 2007, Acute and chronic wounds; current management concepts, V3e, P427
   Hiles M, 2009, SURG INNOV, V16, P26, DOI 10.1177/1553350609331397
   Taner T, 2009, DIS COLON RECTUM, V52, P349, DOI 10.1007/DCR.0b013e31819a3e69
NR 4
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD SEP-OCT
PY 2009
VL 36
IS 5
BP 483
EP 485
DI 10.1097/WON.0b013e3181b51f84
PG 3
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 501ZK
UT WOS:000270423200003
PM 19752656
DA 2026-07-24
ER

PT J
AU Brace, JA
AF Brace, Jacalyn A.
TI THE USE OF NEGATIVE PRESSURE WOUND THERAPY IN VULVAR WOUNDS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Brace, Jacalyn A.] Thomas Jefferson Univ Hosp, Philadelphia, PA 19107 USA.
C3 Thomas Jefferson University
EM jb3130@hotmail.com
NR 0
TC 1
Z9 1
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2009
VL 36
IS 3
SU S
BP S10
EP S11
DI 10.1097/01.WON.0000351910.18266.ee
PG 2
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 446KH
UT WOS:000266120000025
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI Use of vacuum assisted closure (VAC) in genitourinary surgery
SO JOURNAL OF ENDOUROLOGY
LA English
DT Meeting Abstract
NR 0
TC 0
Z9 0
U1 0
U2 0
PU MARY ANN LIEBERT INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 0892-7790
J9 J ENDOUROL
JI J. Endourol.
PD NOV
PY 2004
VL 18
SU 1
BP A109
EP A109
PG 1
WC Urology & Nephrology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Urology & Nephrology
GA 932UO
UT WOS:000229579400425
DA 2026-07-24
ER

PT J
AU Germann, G
AF Germann, G.
TI Here stands the advertisement Reply
SO UNFALLCHIRURG
LA German
DT Letter
ID VACUUM-ASSISTED CLOSURE; THERAPY
C1 Univ Heidelberg, BG Unfallklin Ludwigshafen Plast & Handchirurg, Klin Hand Plast & Rekonstrukt Chirurg, D-67071 Ludwigshafen, Germany.
C3 Ruprecht Karls University Heidelberg
RP Germann, G (通讯作者)，Univ Heidelberg, BG Unfallklin Ludwigshafen Plast & Handchirurg, Klin Hand Plast & Rekonstrukt Chirurg, Ludwig Guttmann Str 13, D-67071 Ludwigshafen, Germany.
EM guenter.germann@urz.uni-heidelberg.de
CR Dieu T, 2003, ANZ J SURG, V73, P1057, DOI 10.1046/j.1445-2197.2003.t01-10-.x
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Isago T, 2003, J DERMATOL, V30, P596, DOI 10.1111/j.1346-8138.2003.tb00441.x
   SEIBERLICH H, 2004, ZENTRALBL CHIR, V129, P125
   STUPPARDT R, 2007, IKK BUNDESVERBAND VO
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Willy C, 2006, ZENTRALBL CHIR S1, V131, P50
   WILLY C, 2006, MMW-FORTSCH MEDIZ S1, V148, P33
   Willy C, 2007, EUR J TRAUMA EMERG S, V33, P33, DOI 10.1007/s00068-007-6143-4
NR 9
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0177-5537
J9 UNFALLCHIRURG
JI Unfallchirurg
PD MAR
PY 2009
VL 112
IS 3
BP 356
EP 356
PG 1
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA 417TI
UT WOS:000264101000013
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI VALIDITY OF KCI'S NEGATIVE PRESSURE WOUND THERAPY PATENTS CONFIRMED
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT News Item
NR 0
TC 0
Z9 0
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD SEP
PY 2009
VL 21
IS 9
BP A20
EP A20
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 507GB
UT WOS:000270839000009
DA 2026-07-24
ER

PT J
AU Karimi, MT
AF Karimi, Mohammad Taghi
TI Tropical pressure wound therapy
SO JOURNAL OF RESEARCH IN MEDICAL SCIENCES
LA English
DT Letter
ID VACUUM-ASSISTED CLOSURE; NEGATIVE-PRESSURE
C1 Isfahan Univ Med Sci, Muscoloskeletal Res Ctr, Esfahan, Iran.
C3 Isfahan University of Medical Sciences
RP Karimi, MT (通讯作者)，Isfahan Univ Med Sci, Muscoloskeletal Res Ctr, Esfahan, Iran.
EM Mohammad.karimi.bioengineering@gmail.com
RI /W-1980-2017
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Deodhar A K, 1997, J Postgrad Med, V43, P52
   Evans D, 2001, BRIT J PLAST SURG, V54, P238, DOI 10.1054/bjps.2001.3547
   Gregor S, 2008, ARCH SURG-CHICAGO, V143, P189, DOI 10.1001/archsurg.2007.54
   Guo S, 2010, J DENT RES, V89, P219, DOI 10.1177/0022034509359125
   Hammell K, 1995, SPINAL CORD INJURY R
   Kirby M, 2007, BR J DIABETES VASC D, V7, P230, DOI DOI 10.1177/1474651407007005060
   Liverman C.T., 2005, SPINAL CORD INJURY P
   Morris GS, 2007, OSTOMY WOUND MANAG, V53, P52
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Pollack S V, 1979, J Dermatol Surg Oncol, V5, P615
   RANZATO E, 2009, MED SURG DERMATOLOGY, V10, P62
NR 12
TC 0
Z9 0
U1 0
U2 0
PU ISFAHAN UNIV MED SCIENCES
PI ISFAHAN
PA HEZARJERIB AVE, PO BOX 81745-319, ISFAHAN, 00000, IRAN
SN 1735-1995
J9 J RES MED SCI
JI J. Res. Med. Sci.
PD AUG
PY 2011
VL 16
IS 8
BP 1092
EP 1093
PG 2
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 833ST
UT WOS:000295905900018
PM 22279488
DA 2026-07-24
ER

PT J
AU Price, RD
   Nagarajan, M
   Srinivasan, JR
AF Price, RD
   Nagarajan, M
   Srinivasan, JR
TI Local anesthetic for change of vacuum-assisted closure dressings
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Letter
C1 Royal Preston Hosp, Dept Plast Surg, Lancashire Teaching Hosp NHS Trust, Preston PR2 9HT, Lancs, England.
C3 Royal Preston Hospital
RP Price, RD (通讯作者)，Royal Preston Hosp, Dept Plast Surg, Lancashire Teaching Hosp NHS Trust, Sharoe Green Lane N, Preston PR2 9HT, Lancs, England.
EM rdp@rick-price.co.uk
RI Manigandan, Nagarajan/E-9005-2019
NR 0
TC 1
Z9 2
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0032-1052
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JUN
PY 2006
VL 117
IS 7
BP 2537
EP 2538
DI 10.1097/01.prs.0000219993.04484.2a
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 055DZ
UT WOS:000238431500094
PM 16772999
DA 2026-07-24
ER

PT J
AU Siddiqui, A
   Tepper, D
AF Siddiqui, Aamir
   Tepper, Donna
TI Muscle Flap Arterialization by Means of Negative-Pressure Wound Therapy
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Editorial Material
C1 [Siddiqui, Aamir; Tepper, Donna] Henry Ford Hosp, Div Plast Surg, Detroit, MI USA.
C3 Henry Ford Health System; Henry Ford Hospital
RP Siddiqui, A (通讯作者)，Henry Ford Hosp, Div Plast Surg, 2799 West Grand Blvd,K-16, Detroit, MI 48230 USA.
EM asiddiq1@hfhs.org
RI siddiqui, aamir/B-1708-2009
NR 0
TC 1
Z9 3
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD FEB
PY 2010
VL 125
IS 2
BP 89E
EP 89E
DI 10.1097/PRS.0b013e3181c72296
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA VM8YY
UT WOS:001055116900026
PM 20124826
DA 2026-07-24
ER

PT J
AU Molnar, JA
AF Molnar, JA
TI Applications of negative pressure wound therapy to thermal injury
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID SKIN
C1 Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27109 USA.
   Wake Forest Univ, Sch Med, Burn Unit, Winston Salem, NC 27109 USA.
C3 Wake Forest University; Wake Forest University
RP Molnar, JA (通讯作者)，Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27109 USA.
EM jmolnar@wfubmc.edu
RI Molnar, Joseph/AEK-5540-2022
CR BURKE JF, 1981, ANN SURG, V194, P413, DOI 10.1097/00000658-198110000-00005
   FEIERABEND TC, 1985, PLAST RECONSTR SURG, V76, P189, DOI 10.1097/00006534-198508000-00002
   Molnar JA, 2000, PLAST RECONSTR SURG, V105, P174, DOI 10.1097/00006534-200001000-00030
   MOLNAR JA, 2002, 11 QUADR C M SEATTL
   MOLNAR JA, 1997, 10 ANN REG BURN SEM
   MOLNAR JA, IN PRESS PLAST RECON
   MOLNAR JA, 2002, AM BURN ASS 34 ANN M
   MOLNAR JA, UNPUB USE SUBATMOSPH
   Morykwas MJ, 1999, J BURN CARE REHABIL, V20, P15, DOI 10.1097/00004630-199901001-00003
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
NR 10
TC 14
Z9 19
U1 1
U2 1
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2004
SU S
BP 17
EP 19
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 817VB
UT WOS:000221203900006
PM 15317239
DA 2026-07-24
ER

PT J
AU Ali, SR
   Mohamedbhai, H
AF Ali, S. R.
   Mohamedbhai, H.
TI Lidocaine analgesia for removal of vacuum-assisted closure dressings
SO ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND
LA English
DT Editorial Material
C1 [Ali, S. R.] Southmead Hosp, Dept Plast Reconstruct & Burns Surg, Bristol, Avon, England.
   [Mohamedbhai, H.] Kings Coll London, London, England.
C3 Southmead Hospital; University of London; King's College London
RP Ali, SR (通讯作者)，Southmead Hosp, Dept Plast Reconstruct & Burns Surg, Bristol, Avon, England.
EM stephenrahemali@gmail.com
NR 0
TC 3
Z9 3
U1 0
U2 0
PU ROYAL COLL SURGEONS ENGLAND
PI LONDON
PA 35-43 LINCOLN'S INN FIELDS, LONDON WC2A 3PN, ENGLAND
SN 0035-8843
EI 1478-7083
J9 ANN ROY COLL SURG
JI Ann. R. Coll. Surg. Engl.
PD APR
PY 2018
VL 100
IS 4
BP 347
EP 347
DI 10.1308/rcsann.2018.0010
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GG9ZA
UT WOS:000433059000034
PM 29364014
DA 2026-07-24
ER

PT J
AU Xie, X
   McGregor, M
   Dendukuri, N
AF Xie, X.
   McGregor, M.
   Dendukuri, N.
TI Effectiveness of negative pressure wound therapy is still unproven reply
SO JOURNAL OF WOUND CARE
LA English
DT Letter
C1 [Xie, X.; McGregor, M.; Dendukuri, N.] McGill Univ, Ctr Hlth, Montreal, PQ, Canada.
   [McGregor, M.] McGill Univ, Div Cardiovasc, Dept Med, Montreal, PQ, Canada.
   [Dendukuri, N.] McGill Univ, Dept Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada.
C3 McGill University; McGill University; McGill University
RP Xie, X (通讯作者)，McGill Univ, Ctr Hlth, Montreal, PQ, Canada.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
J9 J WOUND CARE
JI J. Wound Care
PD FEB
PY 2011
VL 20
IS 2
BP 88
EP 89
DI 10.12968/jowc.2011.20.2.88a
PG 2
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 929YV
UT WOS:000303102700008
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI Negative Pressure Wound-Therapy shortened Healing Period and increased
   Comfort
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT News Item
CR Deroo K, S ADV WOUND CAR 2012
NR 1
TC 0
Z9 0
U1 0
U2 0
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD DEC
PY 2012
VL 137
IS 6
BP 513
EP 513
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 095FP
UT WOS:000315320400006
DA 2026-07-24
ER

PT J
AU Poch, T
   Vidim, T
   Stíchová, M
AF Poch, T.
   Vidim, T.
   Stichova, M.
TI Negative wound pressure therapy in treatment of a pressure ulcer in
   paraplegics
SO CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE
LA Czech
DT Article
DE pressure ulcer; paraplegia; negative pressure wound therapy
AB This is a case report about the treatment of a patient with post-traumatic paraplegia and pressure ulcer using negative pressure wound therapy. After treating the septic state of the patient, the necessary necrectomy was performed, which was followed by performing a sigmoideostomy and orchiectomy. Negative pressure wound therapy was then used to clean the defect. Despite the application of low molecular weight heparin, the condition was complicated by pulmonary embolism and subsequent heart failure, resulting in the death of the patient. This case report also documents the financial and time benefits of this treatment in the care of a complicated patient
C1 [Poch, T.; Vidim, T.; Stichova, M.] Oblastni Nemocnice Kolin AS, Ctr Vaskularnich Intervenci, Chirurg, Kolin, Czech Republic.
RP Poch, T (通讯作者)，Oblastni Nemocnice Kolin AS, Ctr Vaskularnich Intervenci, Zizkova 146, Kolin 28002, Czech Republic.
EM tomas.poch@seznam.cz
CR Mrna L, 2015, Rozhl Chir, V94, P329
   Vasícková L, 2018, CESK SLOV NEUROL N, V81, pS38, DOI 10.14735/amcsnn2018S38
NR 2
TC 0
Z9 0
U1 0
U2 8
PU CZECH MEDICAL SOC
PI PRAGUE 2
PA SOKOLSKA 31, PRAGUE 2 120 26, CZECH REPUBLIC
SN 1210-7859
EI 1802-4041
J9 CESK SLOV NEUROL N
JI Cesk. Slov. Neurol. Neurochir.
PY 2019
VL 82
SU 1
BP S26
EP S28
DI 10.14735/amcsnn2019S26
PG 3
WC Neurosciences; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA JT4SO
UT WOS:000500981300005
DA 2026-07-24
ER

PT J
AU Murakami, M
   Morikage, N
   Samura, M
   Yamashita, O
   Suehiro, K
   Hamano, K
AF Murakami, Masanori
   Morikage, Noriyasu
   Samura, Makoto
   Yamashita, Osamu
   Suehiro, Kotaro
   Hamano, Kimikazu
TI Shoelace technique plus vacuum-assisted closure in leg fasciotomy
SO ANZ JOURNAL OF SURGERY
LA English
DT Letter
C1 [Murakami, Masanori; Morikage, Noriyasu; Samura, Makoto; Yamashita, Osamu; Suehiro, Kotaro; Hamano, Kimikazu] Yamaguchi Univ, Div Vasc Surg, Grad Sch Med, Dept Surg & Clin Sci, Ube, Yamaguchi 755, Japan.
C3 Yamaguchi University
RP Murakami, M (通讯作者)，Yamaguchi Univ, Div Vasc Surg, Grad Sch Med, Dept Surg & Clin Sci, Ube, Yamaguchi 755, Japan.
CR HARRIS I, 1993, INJURY, V24, P565, DOI 10.1016/0020-1383(93)90040-D
   Moran S G, 2003, J Wound Care, V12, P212
   Zannis J, 2009, ANN PLAS SURG, V62, P407, DOI 10.1097/SAP.0b013e3181881b29
NR 3
TC 3
Z9 5
U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1445-1433
EI 1445-2197
J9 ANZ J SURG
JI ANZ J. Surg.
PD OCT
PY 2014
VL 84
IS 10
BP 795
EP 795
DI 10.1111/ans.12662
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AQ4LD
UT WOS:000342767600026
PM 25270316
DA 2026-07-24
ER

PT J
AU Sarkar, D
AF Sarkar, Dibakar
TI Vacuum-Assisted Closure Therapy: A Small Journey in Nitor
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Meeting Abstract
C1 [Sarkar, Dibakar] Natl Inst Traumatol & Orthopaed Rehabil NITOR, Dhaka, Bangladesh.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD NOV
PY 2021
VL 233
IS 5
SU 2
BP E212
EP E212
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WX0PI
UT WOS:000718306700517
DA 2026-07-24
ER

PT J
AU Rand, BC
   Wenke, JC
AF Rand, B. C.
   Wenke, Joseph C.
TI Is Local Antibiotic Delivery Compatible with Negative Pressure Wound
   Therapy?
SO BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
CT International Surgical Congress of the
   Association-of-Surgeons-of-Great-Britain-and-Ireland
CY APR 22-24, 2015
CL Manchester, ENGLAND
SP Assoc Surg Great Britain & Ireland
C1 [Rand, B. C.] Acad Dept Mil Surg & Trauma, San Antonio, TX USA.
   [Wenke, Joseph C.] US Army Inst Surg Res Extrem Trauma, San Antonio, TX USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0007-1323
EI 1365-2168
J9 BRIT J SURG
JI Br. J. Surg.
PD SEP
PY 2015
VL 102
SU 7
SI SI
MA 1018
BP 184
EP 184
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA DA9LN
UT WOS:000368130400624
DA 2026-07-24
ER

PT J
AU Caraganis, A
   Burton, SL
   Goswami, U
   Dincer, H
AF Caraganis, A.
   Burton, S. L.
   Goswami, U.
   Dincer, H.
TI Use of Vacuum Assisted Closure for Massive Subcutaneous Emphysema
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
CT International Conference of the American-Thoracic-Society
CY MAY 18-23, 2018
CL San Diego, CA
SP Amer Thoracic Soc
C1 [Caraganis, A.; Burton, S. L.; Goswami, U.; Dincer, H.] Univ Minnesota, Minneapolis, MN USA.
C3 University of Minnesota System; University of Minnesota Twin Cities
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2018
VL 197
MA A3164
PG 2
WC Critical Care Medicine; Respiratory System
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC General & Internal Medicine; Respiratory System
GA HA1NA
UT WOS:000449978903392
DA 2026-07-24
ER

PT J
AU Pericleous, A
   Dimitrakakis, G
AF Pericleous, Agamemnon
   Dimitrakakis, Georgios
TI Vacuum-assisted closure therapy for deep sternal wound infections
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Letter
C1 [Pericleous, Agamemnon; Dimitrakakis, Georgios] Univ Wales Hosp, Dept Cardiothorac Surg, Cardiff CF4 4XW, S Glam, Wales.
C3 Cardiff University
RP Pericleous, A (通讯作者)，Univ Wales Hosp, Dept Cardiothorac Surg, Cardiff CF4 4XW, S Glam, Wales.
OI DIMITRAKAKIS, GEORGIOS/0000-0002-2426-7178
CR Bruce J, 2001, Health Technol Assess, V5, P1
   Gdalevitch P, 2010, J PLAST RECONSTR AES, V63, P180, DOI 10.1016/j.bjps.2008.08.020
   Luckraz H, 2003, J THORAC CARDIOV SUR, V125, P301, DOI 10.1067/mtc.2003.74
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Steingrimsson S, 2012, INTERACT CARDIOV TH, V15, P406, DOI 10.1093/icvts/ivs254
NR 5
TC 1
Z9 1
U1 0
U2 4
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD SEP
PY 2012
VL 15
IS 3
BP 410
EP 410
DI 10.1093/icvts/ivs349
PG 1
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 025GN
UT WOS:000310175900017
PM 22908178
OA Bronze
DA 2026-07-24
ER

PT J
AU Ogawa, R
   Hyakusoku, H
   Lu, F
   Orgill, DP
AF Ogawa, R.
   Hyakusoku, H.
   Lu, F.
   Orgill, D. P.
TI IN VITRO ANALYSIS OF VACUUM ASSISTED CLOSURE (VAC) THERAPY
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Ogawa, R.; Hyakusoku, H.] Dept Plast Reconstruct & Aesthet Surg, Tokyo, Japan.
   [Ogawa, R.; Lu, F.; Orgill, D. P.] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Plast Surg, Boston, MA 02115 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard Medical School
RI Orgill, Dennis/H-7596-2019; Lu, Fa-Ke/I-7482-2012
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1067-1927
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JAN-FEB
PY 2011
VL 19
IS 1
BP A2
EP A2
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 706JL
UT WOS:000286214600005
DA 2026-07-24
ER

PT J
AU Inaba, K
   Martin, M
AF Inaba, Kenji
   Martin, Matthew
TI Is negative pressure wound therapy beneficial for post-surgical wounds?
SO LANCET
LA English
DT Editorial Material
C1 [Inaba, Kenji; Martin, Matthew] Univ Southern Calif, Keck Sch Med, Dept Surg, Los Angeles, CA 90033 USA.
C3 University of Southern California
RP Inaba, K (通讯作者)，Univ Southern Calif, Keck Sch Med, Dept Surg, Los Angeles, CA 90033 USA.
EM Kenji.Inaba@med.usc.edu
RI Inaba, Kenji/AAC-8532-2020; Martin, Matthew/B-2676-2014
OI Inaba, Kenji/0000-0002-5191-596X; 
CR Arundel C, 2025, LANCET, V405, P1689, DOI 10.1016/S0140-6736(25)00143-6
   Liu ZM, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD010318.pub3
   Martinengo L, 2019, ANN EPIDEMIOL, V29, P8, DOI 10.1016/j.annepidem.2018.10.005
   Seidel D, 2020, JAMA SURG, V155, P469, DOI 10.1001/jamasurg.2020.0414
   Zens Y, 2020, SYST REV-LONDON, V9, DOI 10.1186/s13643-020-01476-6
NR 5
TC 0
Z9 0
U1 0
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0140-6736
EI 1474-547X
J9 LANCET
JI Lancet
PD MAY 10
PY 2025
VL 405
IS 10490
BP 1646
EP 1647
DI 10.1016/S0140-6736(25)00682-8
EA JAN 2025
PG 2
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 3UC3R
UT WOS:001509043200004
PM 40250456
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI Smith & Nephew to launch new negative pressure wound therapy systems
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT News Item
NR 0
TC 0
Z9 0
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD FEB
PY 2008
VL 20
IS 2
BP A18
EP A18
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 266JF
UT WOS:000253430400012
DA 2026-07-24
ER

PT J
AU Wiegering, A
   Dietz, UA
   Corteville, C
   Plassmeier, L
   Jurowich, C
   Germer, CT
   Krajinovic, K
AF Wiegering, Armin
   Dietz, Ulrich A.
   Corteville, Caroline
   Plassmeier, Lars
   Jurowich, Christian
   Germer, Christoph-Thomas
   Krajinovic, Katica
TI Impact of incisional negative pressure wound therapy on perineal wound
   healing after abdominoperineal rectum extirpation
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Article
DE Negative pressure wound therapy; Colorectal cancer; Rectum extirpation
ID INFECTIONS; PREVENTION
AB Perineal wound healing disorders are one of the major complications following abdominoperineal rectum extirpation.
   We evaluated the impact of an "incisional negative pressure wound therapy" (iNPWT) system after abdominoperineal rectum extirpation in six patients. All patients had a neoadjuvant radiochemotherapy with 50.4 Gy and 5-FU. Five of the six patients (83%) experienced complication-free healing of the perineal wound after 5 to 12 days of iNPWT. One patient developed a wound healing disorder 8 days after abdominoperineal rectum extirpation during current iNPWT.
   Use of an iNPWT system can be of favor after abominoperineal rectum extirpation.
C1 [Wiegering, Armin; Dietz, Ulrich A.; Corteville, Caroline; Plassmeier, Lars; Jurowich, Christian; Germer, Christoph-Thomas; Krajinovic, Katica] Univ Wurzburg, Julius Maximilians Univ, Univ Hosp, Dept Gen Visceral Vasc & Pediat Surg, Oberduerrbacherstr 6, D-97080 Wurzburg, Germany.
   [Wiegering, Armin] Univ Wurzburg, Dept Biochem & Mol Biol, D-97074 Wurzburg, Germany.
   [Germer, Christoph-Thomas] Univ Wurzburg, Univ Hosp, Comprehens Canc Ctr Mainfranken, Josef Schneiderstr 6, D-97080 Wurzburg, Germany.
C3 University of Wurzburg; University of Wurzburg; University of Wurzburg
RP Wiegering, A; Krajinovic, K (通讯作者)，Univ Wurzburg, Julius Maximilians Univ, Univ Hosp, Dept Gen Visceral Vasc & Pediat Surg, Oberduerrbacherstr 6, D-97080 Wurzburg, Germany.; Wiegering, A (通讯作者)，Univ Wurzburg, Dept Biochem & Mol Biol, D-97074 Wurzburg, Germany.
EM wiegering_a@ukw.de; krajinovic_k@ukw.de
RI Wiegering, Armin/X-7541-2018; Jurowich, Christian/JLL-2410-2023
CR Blackham AU, 2013, AM J SURG, V205, P647, DOI 10.1016/j.amjsurg.2012.06.007
   Dohmen PM, 2014, MED SCI MONITOR, V20, P1814, DOI 10.12659/MSM.891169
   Grauhan O, 2013, J THORAC CARDIOV SUR, V145, P1387, DOI 10.1016/j.jtcvs.2012.09.040
   Horch RE, 2015, J WOUND CARE, V24, P21, DOI 10.12968/jowc.2015.24.Sup4b.21
   Musters GD, 2014, DIS COLON RECTUM, V57, P1129, DOI 10.1097/DCR.0000000000000182
   Soares KC, 2015, AM J SURG, V209, P324, DOI 10.1016/j.amjsurg.2014.06.022
NR 6
TC 13
Z9 15
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0179-1958
EI 1432-1262
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD FEB
PY 2017
VL 32
IS 2
BP 291
EP 293
DI 10.1007/s00384-016-2704-5
PG 3
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA EK8FO
UT WOS:000394159500017
PM 27844201
DA 2026-07-24
ER

PT J
AU Shah, A
   Kurian, R
   Leung, E
AF Shah, A.
   Kurian, R.
   Leung, E.
TI Use of Negative-Pressure Wound Therapy Following Stoma Reversal Surgery
SO BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
CT International Surgical Conference of the
   Association-of-Surgeons-in-Training (ASIT)
CY MAR 22-24, 2019
CL Belfast, NORTH IRELAND
SP Assoc Surg Training
C1 [Shah, A.; Kurian, R.; Leung, E.] Cty Hosp, Hereford, England.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0007-1323
EI 1365-2168
J9 BRIT J SURG
JI Br. J. Surg.
PD SEP
PY 2019
VL 106
SU 6
SI SI
MA 0586
BP 50
EP 50
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA JA8UZ
UT WOS:000488128100199
DA 2026-07-24
ER

PT J
AU Sasaki, K
   Sasaki, M
   Oshima, J
   Nishijima, A
   Aihara, Y
   Sekido, M
AF Sasaki, Kaoru
   Sasaki, Masahiro
   Oshima, Junya
   Nishijima, Akio
   Aihara, Yukiko
   Sekido, Mitsuru
TI Salvaging exposed microtia cartilage framework with negative pressure
   wound therapy
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Letter
C1 [Sasaki, Kaoru; Sasaki, Masahiro; Oshima, Junya; Nishijima, Akio; Aihara, Yukiko; Sekido, Mitsuru] Univ Tsukuba, Dept Plast & Reconstruct Surg, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan.
C3 University of Tsukuba
RP Sasaki, K (通讯作者)，Univ Tsukuba, Dept Plast & Reconstruct Surg, Tennodai 1-1-1, Tsukuba, Ibaraki, Japan.
EM kaoru-ssk@md.tsukuba.ac.jp
CR Concepción LG, 2019, J PLAST RECONSTR AES, V72, pE3, DOI 10.1016/j.bjps.2018.10.044
   Eto A., 2012, J JPN PLAST RECONSTR, V32, P686
   Siqueira MBP, 2016, WORLD J ORTHOP, V7, P30, DOI 10.5312/wjo.v7.i1.30
NR 3
TC 6
Z9 7
U1 0
U2 1
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD JUN
PY 2021
VL 74
IS 6
BP 1380
EP 1383
DI 10.1016/j.bjps.2020.11.010
EA MAY 2021
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA SJ4FB
UT WOS:000655486600024
PM 33248937
DA 2026-07-24
ER

PT J
AU Bhattacharyya, T
   Mehta, P
   Smith, RM
   Pomahac, B
AF Bhattacharyya, Timothy
   Mehta, Priyesh
   Smith, R. Malcolm
   Pomahac, Bohdan
TI Routine use of wound vacuum-assisted closure does not allow coverage
   delay for open tibia fractures
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID SOFT-TISSUE INJURIES; SEVERE COMPOUND FRACTURES; MANAGEMENT; THERAPY;
   RECONSTRUCTION; COMPLICATIONS; FOUNDATION; EXPERIENCE; TRAUMA; TRENDS
AB Background: Prevention of infection is a paramount concern after open fracture of the tibia. Previous studies have shown that delay in soft-tissue coverage may raise infection rates. Use of vacuum-assisted closure devices in open fracture wounds has become common. The authors analyzed whether use of the vacuum-assisted closure sponge can allow delay of flap coverage for open tibia fractures without an increase in infection rate.
   Methods: The authors identified 38 patients with Gustilo grade IIIB open fractures from their trauma registry with a minimum I-year follow-up. From the medical record, the authors collected information on the time from injury to definitive wound coverage, type of fixation, type of coverage, and demographics. Infected patients were defined as patients that required surgical debridement after coverage with positive cultures.
   Results: Patients who underwent definitive coverage within 7 days had a significantly decreased rate of infection (12.5 percent) compared with patients who had coverage at 7 days or more after injury (57 percent) (p < 0.008). The overall infection rate was 36 percent with routine use of the vacuum-assisted closure sponge. Patients who developed infection had a greater mean time to coverage than patients who did not develop infection (8.9 days versus 4.8 days; p < 0.029).
   Conclusions: Routine use of vacuum-assisted closure with open tibia fractures is safe and provides a good primary dressing over open wounds. For Gustilo grade IIIB tibia fractures, vacuum-assisted closure therapy does not allow delay of soft-tissue coverage past 7 days without a concomitant elevation in infection rates.
C1 [Bhattacharyya, Timothy] Brigham & Womens Hosp, Massachusetts Gen Hosp, Partners Orthoped Trauma Serv, Boston, MA 02118 USA.
   Brigham & Womens Hosp, Div Plast Surg, Boston, MA 02118 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Massachusetts General Hospital; Harvard University;
   Harvard University Medical Affiliates; Brigham & Women's Hospital
RP Bhattacharyya, T (通讯作者)，Brigham & Womens Hosp, Massachusetts Gen Hosp, Partners Orthoped Trauma Serv, 55 Fruit St,Yawkey 3600, Boston, MA 02118 USA.
RI Pomahac, Bohdan/AAH-1792-2019
OI Pomahac, Bohdan/0000-0003-3703-8240
CR Alberts KA, 1999, INJURY, V30, P519, DOI 10.1016/S0020-1383(99)00143-6
   Archdeacon MT, 2006, J ORTHOP TRAUMA, V20, P134, DOI 10.1097/01.bot.0000184147.82824.7c
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bowyer G W, 1993, J R Army Med Corps, V139, P100
   Breugem Corstiaan C, 2006, Int J Low Extrem Wounds, V5, P261, DOI 10.1177/1534734606295030
   Carsenti-Etesse H, 1999, EUR J CLIN MICROBIOL, V18, P315, DOI 10.1007/PL00015012
   Castillo RC, 2005, J ORTHOP TRAUMA, V19, P151, DOI 10.1097/00005131-200503000-00001
   Dedmond BT, 2007, J ORTHOP TRAUMA, V21, P11, DOI 10.1097/BOT.0b013e31802cbc54
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Gopal S, 2000, J BONE JOINT SURG BR, V82B, P959, DOI 10.1302/0301-620X.82B7.10482
   Heitmann C, 2003, J TRAUMA, V54, P379, DOI 10.1097/01.TA.0000028859.26504.7C
   HENRY SL, 1993, CLIN ORTHOP RELAT R, V295, P54
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Leininger BE, 2006, J TRAUMA, V61, P1207, DOI 10.1097/01.ta.0000241150.15342.da
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Okike K, 2006, J BONE JOINT SURG AM, V88A, P2739, DOI 10.2106/JBJS.F.00146
   Olson SA, 1996, J ORTHOP TRAUMA, V10, P395, DOI 10.1097/00005131-199608000-00006
   Olson Steven A, 2003, Instr Course Lect, V52, P623
   OSTERMANN PAW, 1994, ORTHOPEDICS, V17, P397
   Parrett BM, 2006, PLAST RECONSTR SURG, V117, P1315, DOI 10.1097/01.prs.0000204959.18136.36
   Pollak AN, 2000, J BONE JOINT SURG AM, V82A, P1681, DOI 10.2106/00004623-200012000-00001
   Webb Lawrence X, 2002, J Am Acad Orthop Surg, V10, P303
   Webb LX, 2004, WOUNDS, P26
NR 25
TC 107
Z9 131
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD APR
PY 2008
VL 121
IS 4
BP 1263
EP 1266
DI 10.1097/01.prs.0000305536.09242.a6
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 277AA
UT WOS:000254183600023
PM 18349645
DA 2026-07-24
ER

PT J
AU Santos, A
   Endsley, A
   Shrestha, K
   Cruz, A
   Gilman, A
   Huynh, J
   Vaughan, J
AF Santos, Ariel
   Endsley, Avery
   Shrestha, Kripa
   Cruz, Alexis
   Gilman, Anastazia
   Huynh, Jonathan
   Vaughan, Justin
TI NEGATIVE PRESSURE WOUND THERAPY IN EXPLORATORY LAPAROTOMIES WITH
   COEXISTING OSTOMY
SO CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Santos, Ariel; Endsley, Avery; Cruz, Alexis; Gilman, Anastazia; Vaughan, Justin] Texas Tech Univ Hlth Sci Ctr, Lubbock, TX USA.
   [Shrestha, Kripa] Texas Tech Univ Hlth Sci Ctr, Dept Surg, Lubbock, TX USA.
   [Huynh, Jonathan] TTUHSC, Dept Surg, Lubbock, TX USA.
C3 Texas Tech University System; Texas Tech University Health Sciences
   Center; Texas Tech University System; Texas Tech University Health
   Sciences Center; Texas Tech University System; Texas Tech University
   Health Sciences Center
OI Willia, Avery/0000-0001-6981-8490
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0090-3493
EI 1530-0293
J9 CRIT CARE MED
JI Crit. Care Med.
PD JAN
PY 2022
VL 50
IS 1
SU S
MA 689
BP 338
EP 338
PG 1
WC Critical Care Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 0G3HN
UT WOS:000777939300654
DA 2026-07-24
ER

PT J
AU Rand, BC
   Wenke, JC
AF Rand, B. C.
   Wenke, Joseph C.
TI Is Local Antibiotic Delivery Compatible With Negative Pressure Wound
   Therapy?
SO BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
CT International Surgical Congress of the
   Association-of-Surgeons-of-Great-Britain-and-Ireland
CY APR 22-24, 2015
CL Manchester, ENGLAND
SP Assoc Surg Great Britain & Ireland
C1 [Rand, B. C.] Acad Dept Mil Surg & Trauma, San Antonio, TX USA.
   [Wenke, Joseph C.] US Army Inst Surg Res Extrem Trauma, San Antonio, TX USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0007-1323
EI 1365-2168
J9 BRIT J SURG
JI Br. J. Surg.
PD SEP
PY 2015
VL 102
SU 7
SI SI
MA 1018
BP 191
EP 191
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA DA9LN
UT WOS:000368130400648
DA 2026-07-24
ER

PT J
AU Derrick, K
   Schmidt, M
   Robinson, T
   Locke, C
   Kieswetter, K
AF Derrick, Kathleen
   Schmidt, Marisa
   Robinson, Tim
   Locke, Chris
   Kieswetter, Kris
TI A genomic evaluation of novel negative pressure wound therapy dressing
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Derrick, Kathleen; Schmidt, Marisa; Kieswetter, Kris] KCI, San Antonio, TX USA.
   [Robinson, Tim; Locke, Chris] KCI, Ferndown, England.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JUL
PY 2020
VL 28
SU 1
SI SI
MA P.NOV02
BP S58
EP S59
PG 2
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA MJ9PS
UT WOS:000548418300134
DA 2026-07-24
ER

PT J
AU Ashley, SW
AF Ashley, Stanley W.
TI Impact of Negative Pressure Wound Therapy on Wound Healing Foreword
SO CURRENT PROBLEMS IN SURGERY
LA English
DT Editorial Material
NR 0
TC 0
Z9 0
U1 0
U2 1
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0011-3840
EI 1535-6337
J9 CURR PROB SURG
JI Curr. Probl. Surg.
PD JUL
PY 2014
VL 51
IS 7
BP 297
EP 297
DI 10.1067/j.cpsurg.2014.05.002
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AJ8TX
UT WOS:000337981700001
DA 2026-07-24
ER

PT J
AU Wilson, T
   Coleman, B
AF Wilson, Terri
   Coleman, Beverly
TI MANAGING COMPLEX WOUNDS USING NEGATIVE PRESSURE WOUND THERAPY WITH
   INSTILLATION
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Wilson, Terri; Coleman, Beverly] Spinal Cord Injury Unit, Dallas, TX USA.
EM terrijwilson@yahoo.com; beverlyr.Coleman@va.gov
CR Andriessen AE, 2008, WOUNDS, V20, P171
   Back DA, 2013, INT WOUND J, V10, P32, DOI 10.1111/iwj.12183
NR 2
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2018
VL 45
SU 3
MA eCS57
BP S26
EP S26
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA VJ3IV
UT WOS:000579808400063
DA 2026-07-24
ER

PT J
AU Kotz, P
   Fisher, J
AF Kotz, Paula
   Fisher, Jane
TI CREATIVE PRODUCT SELECTION RESULTS IN SUCCESSFUL NEGATIVE PRESSURE WOUND
   THERAPY
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Kotz, Paula; Fisher, Jane] E T Consultant Serv Inc, Asheville, NC USA.
EM etcsinc@charter.net; etcsinc@charter.net
NR 0
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2009
VL 36
IS 3
SU S
BP S20
EP S20
DI 10.1097/01.WON.0000351940.46974.7e
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 446KH
UT WOS:000266120000055
DA 2026-07-24
ER

PT J
AU Grant, MP
   Lamaris, GA
AF Grant, Michael P.
   Lamaris, Gregory A.
TI Enhanced Free Flap Monitoring through Negative Pressure Wound Therapy
   Devices
SO JOURNAL OF RECONSTRUCTIVE MICROSURGERY
LA English
DT Letter
C1 [Lamaris, Gregory A.] Univ Maryland, R Adams Cowley Shock Trauma Ctr, Med Ctr, Div Plast & Reconstruct Surg, Baltimore, MD USA.
   [Lamaris, Gregory A.] Univ Maryland, R Adams Cowley Shock Trauma Ctr, Med Ctr, Div Plast & Reconstruct Surg, 110 S Paca St,Suite 4-S-125, Baltimore, MD 21201 USA.
C3 University System of Maryland; University of Maryland Baltimore;
   University System of Maryland; University of Maryland Baltimore
RP Lamaris, GA (通讯作者)，Univ Maryland, R Adams Cowley Shock Trauma Ctr, Med Ctr, Div Plast & Reconstruct Surg, 110 S Paca St,Suite 4-S-125, Baltimore, MD 21201 USA.
EM glamaris@som.umaryland.edu
CR Anghel EL, 2016, PLAST RECONSTR SURG, V138, p129S, DOI 10.1097/PRS.0000000000002645
   Bi HD, 2018, J RECONSTR MICROSURG, V34, P200, DOI 10.1055/s-0037-1608621
   Eisenhardt SU, 2010, J RECONSTR MICROSURG, V26, P615, DOI 10.1055/s-0030-1267378
   Henry SL, 2011, J RECONSTR MICROSURG, V27, P215, DOI 10.1055/s-0031-1272962
   Lachica RD, 2017, PLAST RECONSTR SURG, V139, p287E, DOI 10.1097/PRS.0000000000002860
NR 5
TC 1
Z9 1
U1 0
U2 3
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 0743-684X
EI 1098-8947
J9 J RECONSTR MICROSURG
JI J. Reconstr. Microsurg.
PD SEP
PY 2024
VL 40
IS 07
BP e1
EP e2
DI 10.1055/a-2238-7706
EA FEB 2024
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA C1A8P
UT WOS:001160942300001
PM 38176426
DA 2026-07-24
ER

PT J
AU Chen, XX
   Tang, QZ
   Luo, HB
   Zhong, XH
AF Chen, Xiaoxia
   Tang, Qingzhu
   Luo, Hongbiao
   Zhong, Xianghong
TI Intervention Effect of Evidence-Based Nursing on Postoperative Recovery
   of Vacuum Sealing Drainage in Patients with High Perianal Abscess with
   Magnetic Resonance Imaging Sequence Images
SO COMPUTATIONAL INTELLIGENCE AND NEUROSCIENCE
LA English
DT Article
AB The purpose of this study was to evaluate the intervention effect of evidence-based nursing (EBN) on vacuum sealing drainage (VSD) recovery of patients with high perianal abscess after vacuum sealing drainage based on magnetic resonance imaging (MRI) sequence images. 60 patients with high perianal abscess were selected, and 30 patients before VSD were selected as the control group. Routine nursing was implemented in the control group, 30 patients after VSD were observed, and EBN was implemented in the observation group. The detection rates of various types of perianal abscess with different sequence combinations were studied, and the effects of EBN on pain and anal function scores of perianal abscess patients were analyzed. Anal function and defecation were assessed, and postoperative complications were calculated. Different combinations of MRI sequences can reach higher detection rates of intersphincter abscess and ischial anal abscess. The observation group had better pain relief and anal function recovery. The complication rate of the observation group was 16.67%, which was significantly lower than that of the control group (P < 0.05). It was confirmed that different MRI sequence combinations had higher detection rates for intersphincter abscess and ischial fossa abscess. EBN can promote the recovery of anal function and reduce complications in patients with perianal abscess.
C1 [Chen, Xiaoxia; Tang, Qingzhu; Luo, Hongbiao; Zhong, Xianghong] Chenzhou First Peoples Hosp, Dept Anorectal Surg, Chenzhou 423000, Hunan, Peoples R China.
RP Zhong, XH (通讯作者)，Chenzhou First Peoples Hosp, Dept Anorectal Surg, Chenzhou 423000, Hunan, Peoples R China.
EM chenxiaoxiaxlng@163.com; tangqingzhugyx7@126.com;
   luohongbiaogznz@yeah.net; 201801110700064@stu.hubu.edu.cn
FU Chenzhou Science and Technology Bureau Project [lcyl2021062]
FX AcknowledgmentsThis work was supported by the Chenzhou Science and
   Technology Bureau Project (no. lcyl2021062).
CR Balaz K, 2020, POL J SURG, V92, P29, DOI 10.5604/01.3001.0013.8158
   Campos TA, 2021, PHOTODIAGN PHOTODYN, V35, DOI 10.1016/j.pdpdt.2021.102437
   Chen BL, 2017, MEDICINE, V96, DOI [10.1097/MD.0000000000006511, 10.1097/md.0000000000006511]
   Ding W, 2021, AM SURGEON, V87, P927, DOI 10.1177/0003134820954829
   Duan HJ, 2020, J WOUND CARE, V29, P510, DOI 10.12968/jowc.2020.29.9.510
   Haghgoshayie E, 2021, CREAT NURS, V27, P94, DOI 10.1891/CRNR-D-19-00080
   Han S, 2021, J HEALTHC ENG, V2021, DOI 10.1155/2021/3706265
   Hiraoka Y, 2020, CLIN J GASTROENTEROL, V13, P26, DOI 10.1007/s12328-019-01003-8
   Huang QQ, 2021, TRANSL PEDIATR, V10, P2489, DOI 10.21037/tp-21-399
   Liu YP, 2021, RESTOR NEUROL NEUROS, V39, P129, DOI 10.3233/RNN-201080
   Ma SY, 2022, MEDICINE, V101, DOI 10.1097/MD.0000000000028278
   Meng J, 2022, STRESS HEALTH, V38, P435, DOI 10.1002/smi.3104
   Pang LM, 2015, AM SURGEON, V81, pE379
   Sun Y, 2021, GUT PATHOG, V13, DOI 10.1186/s13099-021-00457-x
   Um SH, 2021, PEDIATR GASTROENTERO, V24, P564, DOI 10.5223/pghn.2021.24.6.564
   Wang JP, 2019, ANZ J SURG, V89, P244, DOI 10.1111/ans.14874
   Wang X, 2020, MEDICINE, V99, DOI 10.1097/MD.0000000000019183
   Wu XM, 2022, J COSMET DERMATOL-US, V21, P2140, DOI 10.1111/jocd.14375
   Xue X, 2021, INT WOUND J, V18, P639, DOI 10.1111/iwj.13565
   Yang J, 2021, CONTRAST MEDIA MOL I, V2021, DOI 10.1155/2021/9066128
   Yu X, 2021, MEDICINE, V100, DOI 10.1097/MD.0000000000025990
   Yue JK, 2020, MEDICINA-LITHUANIA, V56, DOI 10.3390/medicina56020087
   Zhang JJ, 2020, J ADV NURS, V76, P3623, DOI 10.1111/jan.14515
   Zhong ZF, 2019, EXP THER MED, V18, P1539, DOI 10.3892/etm.2019.7773
NR 24
TC 3
Z9 4
U1 0
U2 7
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1687-5265
EI 1687-5273
J9 COMPUT INTEL NEUROSC
JI Comput. Intell. Neurosci.
PD JUN 24
PY 2022
VL 2022
AR 1405134
DI 10.1155/2022/1405134
PG 7
WC Mathematical & Computational Biology; Neurosciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Mathematical & Computational Biology; Neurosciences & Neurology
GA 3K6AJ
UT WOS:000834156700016
PM 35785101
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Atwood, RE
   Bradley, MJ
   Elster, EA
AF Atwood, Rex E.
   Bradley, Matthew J.
   Elster, Eric A.
TI Use of negative pressure wound therapy on conflict-related wounds
SO LANCET GLOBAL HEALTH
LA English
DT Editorial Material
C1 [Atwood, Rex E.; Bradley, Matthew J.] Walter Reed Natl Mil Med Ctr, Bethesda, MD USA.
   [Atwood, Rex E.; Bradley, Matthew J.; Elster, Eric A.] Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA.
C3 Walter Reed National Military Medical Center; Uniformed Services
   University of the Health Sciences - USA
RP Elster, EA (通讯作者)，Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA.
EM eric.elster@usuhs.edu
RI Elster, Eric/ABG-6091-2021; Bradley, Matthew/JHU-7574-2023
OI Elster, Eric/0000-0002-0981-2748; 
CR Älgå A, 2020, LANCET GLOB HEALTH, V8, pE423, DOI 10.1016/S2214-109X(19)30547-9
   Connolly M, 2016, MILITARY MED RES, V3, DOI 10.1186/s40779-016-0080-7
   Cubano M, 2018, EMERGENCY WAR SURG, P97
   Lisboa FA, 2019, ANN SURG, V270, P535, DOI 10.1097/SLA.0000000000003470
   Milcheski Dimas André, 2013, Rev. Col. Bras. Cir., V40, P312
   Tiwari N, 2013, HEART LUNG CIRC, V22, P542, DOI 10.1016/j.hlc.2012.11.013
NR 6
TC 9
Z9 14
U1 0
U2 3
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 2214-109X
J9 LANCET GLOB HEALTH
JI Lancet Glob. Health
PY 2020
VL 8
IS 3
BP E319
EP E320
DI 10.1016/S2214-109X(20)30041-3
PG 2
WC Public, Environmental & Occupational Health
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Public, Environmental & Occupational Health
GA KN5BJ
UT WOS:000514852000009
PM 32087160
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Petrozzello, D
AF Petrozzello, Donna
TI Perioperative teams play critical role in negative pressure wound
   therapy
SO AORN JOURNAL
LA English
DT Editorial Material
CR Bak J., 2015, ALEXANDERS CARE PATI, P253
   KCI Medical, 2015, VAC THER CLIN GUID R
   Mafi R, 2014, INT J INFECT CONTROL, V10, pi2, DOI [10.3396/IJIC.v10i2.011.14, DOI 10.3396/IJIC.V10I2.011.14]
   Mark KS, 2014, SURG INNOV, V21, P345, DOI 10.1177/1553350613503736
   Mendez-Eastman S, 2001, Adv Skin Wound Care, V14, P314, DOI 10.1097/00129334-200111000-00015
   SAMES CP, 1977, BMJ-BRIT MED J, V2, P1223
NR 6
TC 0
Z9 0
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0001-2092
EI 1878-0369
J9 AORN J
JI AORN J.
PD AUG
PY 2017
VL 106
IS 2
SI SI
BP P7
EP P9
DI 10.1016/S0001-2092(17)30650-6
PG 3
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA FF0BJ
UT WOS:000408566900002
DA 2026-07-24
ER

PT J
AU Cook, SJ
   Jeyapalina, S
   Nichols, FR
   Bachus, KN
AF Cook, S. J.
   Jeyapalina, S.
   Nichols, F. R.
   Bachus, K. N.
TI CONTINUOUS VACUUM-ASSISTED CLOSURE LIMITS EPITHELIAL DOWNGROWTH AROUND
   PERCUTANEOUS DEVICES
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Cook, S. J.; Jeyapalina, S.; Nichols, F. R.; Bachus, K. N.] Univ Utah, Salt Lake City, UT USA.
   [Bachus, K. N.] VA Salt Lake City Hlth Care Syst, Salt Lake City, UT USA.
C3 Utah System of Higher Education; University of Utah; US Department of
   Veterans Affairs
RI Bachus, Kent/KYO-7869-2024
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR
PY 2014
VL 22
IS 2
BP A36
EP A36
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA AC9DV
UT WOS:000332835400037
DA 2026-07-24
ER

PT J
AU Saklani, AP
   Delicata, RJ
AF Saklani, AP
   Delicata, RJ
TI Vacuum assisted closure system in the management of enterocutaneous
   fistula
SO POSTGRADUATE MEDICAL JOURNAL
LA English
DT Letter
C1 Nevill Hall Hosp, Abergavenny, Wales.
RP Saklani, AP (通讯作者)，Nevill Hall Hosp, Abergavenny, Wales.
OI Saklani, Avanish/0000-0003-4498-7612
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
NR 2
TC 4
Z9 9
U1 0
U2 0
PU BRITISH MED JOURNAL PUBL GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 0032-5473
J9 POSTGRAD MED J
JI Postgrad. Med. J.
PD NOV
PY 2002
VL 78
IS 925
BP 699
EP 699
DI 10.1136/pmj.78.925.699
PG 1
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 633VZ
UT WOS:000180306300027
PM 12496345
OA Bronze
DA 2026-07-24
ER

PT J
AU Yuh, DD
   Albaugh, M
   Ullrich, S
   Conte, JV
AF Yuh, DD
   Albaugh, M
   Ullrich, S
   Conte, JV
TI Treatment of ventricular assist device driveline infection with
   vacuum-assisted closure system
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID WOUND CONTROL
AB Deep driveline infection is a serious complication after left ventricular assist device implantation. Current treatment strategies are associated with significant morbidity related to healing or relocation of the driveline tract. We present a case of deep driveline infection successfully treated with a vacuum-assisted closure system as a potentially improved alternative therapy.
C1 Johns Hopkins Univ Hosp, Div Cardiac Surg, Baltimore, MD 21287 USA.
C3 Johns Hopkins University; Johns Hopkins Medicine
RP Yuh, DD (通讯作者)，Johns Hopkins Univ Hosp, Div Cardiac Surg, 600 N Wolfe St,Blalock 618, Baltimore, MD 21287 USA.
EM dyuh@csurg.jhmi.jhu.edu
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   FISHER SA, 1997, CLIN INFECT DIS, V24, P18
   Grossi P, 2001, TRANSPLANT P, V33, P1969, DOI 10.1016/S0041-1345(00)02757-3
   Holman WL, 2003, ANN THORAC SURG, V75, pS48, DOI 10.1016/S0003-4975(03)00479-X
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Pasque MK, 2002, ANN THORAC SURG, V74, P1267, DOI 10.1016/S0003-4975(02)03752-9
   Rose EA, 2001, NEW ENGL J MED, V345, P1435, DOI 10.1056/NEJMoa012175
NR 8
TC 22
Z9 24
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD OCT
PY 2005
VL 80
IS 4
BP 1493
EP 1495
DI 10.1016/j.athoracsur.2004.03.043
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 972GK
UT WOS:000232442100052
PM 16181898
DA 2026-07-24
ER

PT J
AU Gillespie, BM
AF Gillespie, Brigid M.
CA ADding Negative pRESSure Improve H
TI Prophylactic Use of Negative Pressure Wound Therapy After Cesarean
   Delivery
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Letter
C1 [Gillespie, Brigid M.] Griffith Univ, Ctr Hlth Practice Innovat, NHMRC Ctr Res Excellence Nursing NCREN, Gold Coast, Australia.
   [Gillespie, Brigid M.] Griffith Univ, Menzies Hlth Inst Qld, Gold Coast, Australia.
C3 Griffith University; Griffith University; Menzies Health Institute
   Queensland
RP Gillespie, BM (通讯作者)，Griffith Univ, Ctr Hlth Practice Innovat, NHMRC Ctr Res Excellence Nursing NCREN, Gold Coast, Australia.
RI Gillespie, Brigid/E-7799-2012
OI Gillespie, Brigid/0000-0003-3186-5691
CR Chaboyer W, 2014, HEALTHCARE, V2, P417, DOI 10.3390/healthcare2040417
   Echebiri NC, 2015, OBSTET GYNECOL, V125, P299, DOI 10.1097/AOG.0000000000000634
NR 2
TC 1
Z9 1
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0029-7844
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD JUL
PY 2015
VL 126
IS 1
BP 214
EP 214
DI 10.1097/AOG.0000000000000937
PG 1
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA DC2WS
UT WOS:000369080100036
PM 26241279
DA 2026-07-24
ER

PT J
AU De Leon, JC
   Karia, RA
AF De Leon, Jorge C.
   Karia, Ravi A.
TI Incisional and Surrounding Periarticular Soft Tissue Management With
   Negative Pressure Therapy
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE incisional wound therapy; lower extremity periarticular fractures;
   negative pressure incisional wound therapy
ID WOUND THERAPY; INTERNAL-FIXATION; TIBIAL PLAFOND; OPEN REDUCTION;
   FRACTURES; COMPLICATIONS; PREVENTION
AB Periarticular injuries of the lower extremity are known for wound healing and infection complications. The role for incisional negative pressure wound therapy for lower extremity periarticular fractures has expanded over the last 10 years in hopes of minimizing complications. To date, there is no standardized published protocol of how negative pressure wound therapy is best used in lower extremity periarticular fractures. A review of strategies to decrease complications associated with the operative management of lower extremity periarticular fractures to include the use of incisional negative pressure wound therapy is presented.
C1 [De Leon, Jorge C.; Karia, Ravi A.] UT Hlth San Antonio, Dept Orthopaed, 4502 Med Dr, San Antonio, TX 78229 USA.
C3 University of Texas System; University of Texas at San Antonio
RP Karia, RA (通讯作者)，UT Hlth San Antonio, Dept Orthopaed, 4502 Med Dr, San Antonio, TX 78229 USA.
EM karia@uthscsa.edu
CR Akiboye F, 2017, CURR DIABETES REP, V17, DOI 10.1007/s11892-017-0839-6
   [Anonymous], 2011, DIABETES RES CLIN PR, V93, P299, DOI 10.1016/j.diabres.2011.03.012
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   Chang YP, 2019, JBJS REV, V7, DOI 10.2106/JBJS.RVW.17.00197
   Egbert RC, 2020, SCI REP-UK, V10, DOI 10.1038/s41598-020-58987-4
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   Koski A, 2005, SCAND J SURG, V94, P243, DOI 10.1177/145749690509400313
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   Prabhakar G, 2021, INT ORTHOP, V45, P275, DOI 10.1007/s00264-020-04816-2
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NR 31
TC 0
Z9 0
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD SEP
PY 2022
VL 36
SU 4
BP S26
EP S30
DI 10.1097/BOT.0000000000002429
PG 5
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 3Y2NF
UT WOS:000843564400007
PM 35994306
DA 2026-07-24
ER

PT J
AU Tekin, EE
   Yesiltas, MA
   Uysal, A
   Haberal, I
AF Tekin, Esra Erturk
   Yesiltas, Mehmet Ali
   Uysal, Ayhan
   Haberal, Ismail
TI The effectiveness of vacuum-assisted closure therapy in patients with
   infected venous leg ulcers
SO CARDIOVASCULAR JOURNAL OF AFRICA
LA English
DT Article
DE vacuum-assisted closure therapy; venous ulcer; post-thrombotic syndrome;
   wound infection; rapid wound healing
ID MANAGEMENT; MICROBIOLOGY; PREVALENCE; POPULATION; SOCIETY; TRIAL
AB Aim: In this study, we aimed to investigate the effect of vacu-um-assisted closure therapy on venous stasis wound healing in patients with chronic venous leg ulcers. Methods: Vacuum-assisted closure therapy was applied on a total of 14 venous leg ulcers. All patients had post-thrombotic syndrome. Quantitative wound culture samples were obtained before the procedure and local wound assessments were performed. The primary outcome measures included wound healing as assessed by a local wound examination during each dressing change and the rate and velocity of ulcer reduc-tion. Wound healing was defined as the complete closure of the ulcer, while rapid wound healing was defined as a >= 30% reduction in the ulcer size by week four. Results: No surgical debridement or surgical corrective procedure was applied in any patient. The mean length of hospital stay was 32.3 days. The mean number of vacuum-assisted closure therapies for each case was 17.8 and the mean time to dressing change was 72.3 hours. Multidrug-resistant Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus were detected in three and four patients, respectively. Wound culture results became negative after a mean duration of vacuum-assisted closure therapy of 12.1 days. None of the patients needed antibiotic therapy until the procedure was completed. Compared to baseline, the mean ulcer reduction rates were 46.4% for the first six applications and 72.8% for the subsequent applications. Conclusion: Our study results suggest that vacuum-assisted closure therapy promotes rapid wound healing in patients with severe post-thrombotic syndrome with venous stasis leg ulcers, and reduces the need for antibiotics by reducing the biological burden.
C1 [Tekin, Esra Erturk] Mersin City Training & Res Hosp, Dept Cardiovasc Surg, Mersin, Turkey.
   [Yesiltas, Mehmet Ali] Bakirkoy Dr Sadi Konuk Training & Res Hosp, Dept Cardiovasc Surg, Istanbul, Turkey.
   [Uysal, Ayhan] Firat Univ, Cardiovasc Surg Clin, Med Fac, Elazig, Turkey.
   [Haberal, Ismail] Istanbul Univ, Dept Cardiovasc Surg, Cerrahpasa Inst Cardiol, Istanbul, Turkey.
C3 Bakirkoy Dr. Sadi Konuk Research & Training Hospital; Firat University;
   Istanbul University
RP Tekin, EE (通讯作者)，Mersin City Training & Res Hosp, Dept Cardiovasc Surg, Mersin, Turkey.
EM dresraer@yahoo.com
RI /D-8323-2019; erturk tekin, esra/AFI-8190-2022; /W-5118-2018; YESILTAS,
   Mehmet Ali/D-8568-2019
OI YESILTAS, Mehmet Ali/0000-0002-5208-0626
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NR 44
TC 4
Z9 5
U1 0
U2 4
PU CLINICS CARDIVE PUBL PTY LTD
PI DURBANVILLE
PA PO BOX 1013, DURBANVILLE, 7551, SOUTH AFRICA
SN 1995-1892
EI 1680-0745
J9 CARDIOVASC J AFR
JI Cardiovasc. J. Afr.
PD MAR-APR
PY 2022
VL 33
IS 2
BP 44
EP 50
DI 10.5830/CVJA-2021-034
EA JUL 2021
PG 7
WC Cardiac & Cardiovascular Systems
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA 1S3IG
UT WOS:000720104000001
PM 34309617
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Gustafsson, RI
   Sjögren, J
   Ingemansson, R
AF Gustafsson, RI
   Sjögren, J
   Ingemansson, R
TI Deep sternal wound infection:: A sternal-sparing technique with
   vacuum-assisted closure therapy
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID POSTOPERATIVE MEDIASTINITIS; CARDIAC-SURGERY; EXPERIENCE; STERNOTOMY;
   MANAGEMENT; SYSTEM; RECONSTRUCTION; FLAPS
AB Background. Vacuum-assisted closure therapy is a novel treatment employed to aid wound healing in different areas of the body and recently also in sternotomy wounds. Aggressive vacuum-assisted closure treatment of the sternum in postoperative deep wound infection enhances sternal preservation and the rate of possible rewiring.
   Methods. The records of 40 consecutive patients with deep sternal wound infection were reviewed. Sternal bone sparing was achieved by using layers of paraffin gauze (Jelonet; Smith and Nephew Medical, Hull, UK) at the bottom of the wound in order to cover and protect visible parts of the right ventricle, lung tissue, and grafts from the sternal edges. Two separate layers of polyurethane foam (KCI, Copenhagen, Denmark) were placed so as to fit between the sternal edges and subcutaneously. A continuous negative pressure of 125 mm Hg was applied and subsequent revision was made exclusively in non-granulation areas.
   Results. There were no deaths during the 90 days of follow-up. Three late deaths unrelated to the infection and three subcutaneous fistulas occurred during the total follow-up period (3 to 41 months). The median duration of the vacuum-assisted closure therapy was 10 days (range, 3 to 34). The series represents a total of 474 days with the vacuum-assisted closure device without serious adverse events.
   Conclusions. In our opinion this modified vacuum-assisted closure therapy is a safe and reproducible option to bridge patients with postoperative deep sternal wound infection to complete healing. Reconstruction of the sternum was achieved in all patients without the use of muscle or omental flap surgery. (C) 2003 by The Society of Thoracic Surgeons.
C1 Univ Lund Hosp, Heart & Lund Div, Dept Cardiothorac Surg, SE-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital
RP Gustafsson, RI (通讯作者)，Univ Lund Hosp, Heart & Lund Div, Dept Cardiothorac Surg, SE-22185 Lund, Sweden.
RI ; Sjögren, Johan/AAZ-6448-2021
OI Ingemansson, Richard/0000-0001-7623-8953; 
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 21
TC 83
Z9 100
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD DEC
PY 2003
VL 76
IS 6
BP 2048
EP 2053
DI 10.1016/S0003-4975(03)01337-7
PG 6
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 750JA
UT WOS:000186986500057
PM 14667639
DA 2026-07-24
ER

PT J
AU Kutschka, I
   Frauendorfer, P
   Harringer, W
AF Kutschka, I
   Frauendorfer, P
   Harringer, W
TI Vacuum assisted closure therapy improves early postoperative lung
   function in patients with large sternal wounds
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Country Congress on VAC Therapy for Outpatients as well as
   In-Hospital Patients
CY MAY 21-22, 2003
CL Mainz, GERMANY
DE vacuum therapy; sternal infection; lung function
AB Vacuum assisted closure of sternal wounds is a sound strategy for patients with severe poststernotomy mediastinitis and sternal bone necrosis. As a bridging therapy to reconstructive surgery it provides an adequate temporary stabilization of the thorax. It enhances lung function and reduces pulmonary complications.
C1 Klin Herz Thorax & Gefasschirurg, Stadt Klinikum Braunschweig, D-38126 Braunschweig, Germany.
RP Kutschka, I (通讯作者)，Klin Herz Thorax & Gefasschirurg, Stadt Klinikum Braunschweig, Salzdahlumerstr 90, D-38126 Braunschweig, Germany.
EM htg@klinikum-braunschweig.de
OI Harringer, Wolfgang/0000-0001-8899-4828; Kutschka,
   Ingo/0000-0002-7358-3513
NR 0
TC 14
Z9 20
U1 0
U2 1
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD MAY
PY 2004
VL 129
SU 1
BP S33
EP S34
DI 10.1055/s-2004-822607
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 826GF
UT WOS:000221816600010
PM 15168280
DA 2026-07-24
ER

PT J
AU Manfredi, MA
   Clark, SJ
   Staffa, SJ
   Ngo, PD
   Smithers, CJ
   Hamilton, TE
   Jennings, RW
AF Manfredi, Michael A.
   Clark, Susannah J.
   Staffa, Steven J.
   Ngo, Peter D.
   Smithers, C. Jason
   Hamilton, Thomas E.
   Jennings, Russell W.
TI Endoscopic Esophageal Vacuum Therapy: A Novel Therapy for Esophageal
   Perforations in Pediatric Patients
SO JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
LA English
DT Article
DE esophageal atresia; esophageal leak; esophageal perforation; esophageal
   stent; esophageal vacuum-assisted closure; negative-pressure wound
   therapy
ID ASSISTED CLOSURE; ANASTOMOTIC LEAKAGE; STENT; MANAGEMENT; DEFECTS
AB Background: Esophageal perforation is a potentially life-threatening problem if not quickly diagnosed and treated appropriately. Negative-pressure wound therapy, commercially known as V.A.C. therapy, was developed in the early 1990s and is now standard of care for chronic surface wounds, ulcers, and burns. Adapting vacuum sponge therapy for use intraluminally for perforations of the esophagus was first reported in 2008. We report the first pediatric experience on a customized esophageal vacuum-assisted closure (EVAC) device for closure of esophageal perforations. Aim: To evaluate the technical feasibility, safety, and efficacy of EVAC in a pediatric population with esophageal perforations and compare efficacy to a cohort of patients who underwent stenting for esophageal perforation. Methods: We performed an institutional review board-approved retrospective chart review on all patients who underwent EVAC for esophageal perforations (October 2013-September 2017) and who underwent externally removable stent placement for esophageal perforation (January 2010-December 2017) at our institution. Our primary aim was to evaluate technical feasibility, efficacy, and safety in the treatment of pediatric esophageal perforations. A secondary aim was to compare the efficacy of EVAC to esophageal stenting in healing esophageal perforations in our pediatric population. Results: A total of 17 patients with esophageal atresia underwent therapy for esophageal perforation. Eight sponges were placed for surgical perforation and 9 were placed after endoscopic therapy perforation. The median age of patients was 24 months with the youngest patient being 3 months of age. The success rate of EVAC to seal all esophageal perforations was 88% (15/17). The success rate was similar in both subgroups: surgical anastomotic leaks at 88% (7/8) and endoscopic therapy leaks at 89% (8/9). There were no technical failures with placement. The stent group had a total of 24 patients: 19 were placed secondary to perforations from endoscopic therapy and 5 were placed secondary to surgical anastomotic perforations. The success rate of stents to seal all esophageal perforations was 63% (15/24). The success rate in the subgroups was 74% (14/19) for endoscopic therapy leaks and 20% (1/5) for surgical anastomotic leaks. In comparing success of EVAC and stent therapy, we found a statistically significant difference in favor of EVAC in healing surgical anastomotic perforations (P = 0.032). There was, however, no statistical difference in healing endoscopic therapy perforations (P = 0.360). Conclusions: EVAC is a novel, promising technique for the treatment of esophageal perforations in a pediatric population. This treatment is comparable to esophageal stenting in iatrogenic endoscopic therapy perforations and superior to stenting surgical perforations. Further prospective studies are needed to compare the effectiveness of EVAC to esophageal stenting. Improvement in device design and customization could further improve success and ease of placement.
C1 [Manfredi, Michael A.; Ngo, Peter D.] Boston Childrens Hosp, Div Gastroenterol, Boston, MA USA.
   [Manfredi, Michael A.; Clark, Susannah J.; Ngo, Peter D.; Smithers, C. Jason; Hamilton, Thomas E.; Jennings, Russell W.] Boston Childrens Hosp, Esophageal & Airway Treatment Ctr, Boston, MA USA.
   [Clark, Susannah J.; Smithers, C. Jason; Hamilton, Thomas E.; Jennings, Russell W.] Boston Childrens Hosp, Dept Surg, Boston, MA USA.
   [Staffa, Steven J.] Boston Childrens Hosp, Dept Anesthesiol Perioperat & Pain Med, Boston, MA USA.
C3 Harvard University; Harvard University Medical Affiliates; Boston
   Children's Hospital; Harvard University; Harvard University Medical
   Affiliates; Boston Children's Hospital; Harvard University; Harvard
   University Medical Affiliates; Boston Children's Hospital; Harvard
   University; Harvard University Medical Affiliates; Boston Children's
   Hospital
RP Manfredi, MA (通讯作者)，Boston Childrens Hosp, 300 Longwood Ave, Boston, MA 02132 USA.
EM Michael.Manfredi@childrens.harvard.edu
RI Hamilton, Thomas/GQB-4837-2022
OI Clark, Susannah/0000-0003-4873-0582
CR Bludau M, 2014, SURG ENDOSC, V28, P896, DOI 10.1007/s00464-013-3244-5
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
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   Heits N, 2014, ANN THORAC SURG, V97, P1029, DOI 10.1016/j.athoracsur.2013.11.014
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Kuehn F, 2016, J GASTROINTEST SURG, V20, P237, DOI 10.1007/s11605-015-3044-4
   Laukoetter MG, 2017, SURG ENDOSC, V31, P2687, DOI 10.1007/s00464-016-5265-3
   Leeds SG, 2016, SURG OBES RELAT DIS, V12, P1278, DOI 10.1016/j.soard.2016.01.017
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   Schorsch T, 2013, SURG ENDOSC, V27, P2040, DOI 10.1007/s00464-012-2707-4
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   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
NR 17
TC 46
Z9 59
U1 0
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0277-2116
EI 1536-4801
J9 J PEDIATR GASTR NUTR
JI J. Pediatr. Gastroenterol. Nutr.
PD DEC
PY 2018
VL 67
IS 6
BP 706
EP 712
DI 10.1097/MPG.0000000000002073
PG 7
WC Gastroenterology & Hepatology; Nutrition & Dietetics; Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Nutrition & Dietetics; Pediatrics
GA HD8CI
UT WOS:000452781500011
PM 29927863
DA 2026-07-24
ER

PT J
AU Ewart, E
   Kaur, G
AF Ewart, E.
   Kaur, G.
TI THE USE OF VACUUM ASSISTED CLOSURE IN COMPLEX COLORECTAL WOUNDS
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Ewart, E.; Kaur, G.] Scunthorpe Gen Hosp, Scunthorpe, England.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1067-1927
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV-DEC
PY 2010
VL 18
IS 6
MA 018
BP A81
EP A81
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 677KJ
UT WOS:000283991000019
DA 2026-07-24
ER

PT J
AU Renner, C
   Reschke, S
   Richter, W
AF Renner, Christian
   Reschke, Susanne
   Richter, Wolfgang
TI Thoracic Empyema After Pneumonectomy: Intrathoracic Application of
   Vacuum-Assisted Closure Therapy
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
AB We report the use of vacuum-assisted closure (V.A.C. Therapy, KCI Medical, Wiesbaden, Germany) to treat an intrathoracic empyema that occurred after resection of the right lung. Successful closure of the thoracic cavity was achieved with an omental plombage. (Ann Thorac Surg 2010;89:603-4) (C) 2010 by The Society of Thoracic Surgeons
C1 [Renner, Christian; Reschke, Susanne; Richter, Wolfgang] Kliniken Kreis Muehldorf Inn, Dept Surg, D-84453 Muehldorf, Germany.
RP Renner, C (通讯作者)，Kliniken Kreis Muehldorf Inn, Dept Surg, Krankenhausstr 1, D-84453 Muehldorf, Germany.
EM mail@drchristianrenner.de
CR Ditterich D, 2006, ZBL CHIR, V131, pS133, DOI 10.1055/s-2006-921499
   Ditterich D, 2004, ZBL CHIR, V129, pS137
   Varker KA, 2006, ANN THORAC SURG, V81, P723, DOI 10.1016/j.athoracsur.2004.10.040
NR 3
TC 10
Z9 10
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD FEB
PY 2010
VL 89
IS 2
BP 603
EP 604
DI 10.1016/j.athoracsur.2009.06.037
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 547BV
UT WOS:000273861100050
PM 20103353
DA 2026-07-24
ER

PT J
AU Descheemaeker, V
   Aillet, S
   Morcel, K
   Gravier, A
   Meyer, N
   Leveque, J
AF Descheemaeker, V.
   Aillet, S.
   Morcel, K.
   Gravier, A.
   Meyer, N.
   Leveque, J.
TI Pyoderma gangrenosum and breast cancer: A case report
SO JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION
LA French
DT Article
DE Breast cancer; Pyoderma gangrenosum; Surgery
ID GANGRAENOSUM
AB The authors report a case of pyoderma gangrenosum (PG) following a breast lumpectomy for a relapse of a breast cancer. The treatment has associated a systemic corticosteroid therapy and local wound care with vacuum assisted closure Vacuum-Assisted Closure (R) and skin graft. (C) 2008 Elsevier Masson SAS. Tous droits reserves.
C1 [Descheemaeker, V.; Aillet, S.; Morcel, K.; Leveque, J.] CHU Anne de Bretagne, Dept Obstet Gynecol & Med Reprod, Unite Chirurg Plast & Reconstruct, F-35203 Rennes 2, France.
   [Descheemaeker, V.; Leveque, J.] Ctr Reg Lutte Canc Eugene Marquis, Dept Chirurg, Rennes, France.
   [Gravier, A.] Ctr Hosp Y Le Foll, Serv Gynecol Obstet, St Brieuc, France.
   [Meyer, N.] CHU Pontchaillou, Serv Dermatol, Rennes, France.
C3 CHU Rennes; UNICANCER; Centre Eugene Marquis; Universite de Rennes; CHU
   Rennes; Universite de Rennes
RP Leveque, J (通讯作者)，CHU Anne de Bretagne, Dept Obstet Gynecol & Med Reprod, Unite Chirurg Plast & Reconstruct, 16 Blvd Bulgarie,BP 90347, F-35203 Rennes 2, France.
EM jean.leveque@chu-rennes.fr
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   Henseler H, 2001, CHIRURG, V72, P1196, DOI 10.1007/s001040170060
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   Mahé E, 2002, PRESSE MED, V31, P1476
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   Wollina Uwe, 2002, Am J Clin Dermatol, V3, P149
NR 31
TC 12
Z9 12
U1 0
U2 1
PU ELSEVIER MASSON, CORPORATION OFFICE
PI PARIS
PA 65 CAMILLE DESMOULINS CS50083 ISSY-LES-MOULINEAUX, 92442 PARIS, FRANCE
SN 0368-2315
EI 1773-0430
J9 J GYNECOL OBST BIO R
JI J. Gynecol. Obstet. Biol. Reprod.
PD OCT
PY 2008
VL 37
IS 6
BP 618
EP 621
DI 10.1016/j.jgyn.2008.06.001
PG 4
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 381ZT
UT WOS:000261575100013
PM 18640792
DA 2026-07-24
ER

PT J
AU Gu, X
   Chen, W
   Yuan, K
   Tan, J
   Sun, SG
AF Gu, Xiang
   Chen, Wei
   Yuan, Kun
   Tan, Jian
   Sun, Suguang
TI The efficacy of artificial dermis combined with continuous vacuum
   sealing drainage in deep neck multiple spaces infection treatment
SO MEDICINE
LA English
DT Article
DE efficacies analysis; multiple spaces infection; the neck abscess; vacuum
   sealing drainage
ID ANTIBIOTIC-SENSITIVITY; MICROBIOLOGY; HEAD; ABSCESSES
AB Deep neck abscesses are dangerous. Artificial dermis combined with seal negative pressure drainage is a new technique for treating refractory wounds. To compare the efficacy of vacuum sealing drainage (VSD) with that of traditional incision drainage approaches for treating deep neck multiple spaces infections. This retrospective analysis includes patient data from our hospital collected from January 2010 to March 2020. A total of 20 cases were identified. Based on the treatment methods, the patients were divided into the VSD group and the traditional group. Inflammation indicators (white blood count, WBC), duration of antibiotic use, hospitalization time, doctors' workload (frequency of dressing changes) and treatment cost were analyzed and compared between the two groups. Of the 20 patients, 11 patients underwent treatment with VSD, while the other 9 underwent traditional treatment. All patients were cured after treatment. Compared with the traditional group, the VSD group had a slower decline in the inflammation index, shorter duration of antibiotic use, shorter hospital stay, and lower doctor workloads (P < .001). There was no significant difference in treatment cost between the two groups (P > .05). VSD technology can markedly improve the therapeutic effect of deep neck multiple spaces infection. This treatment method can be used to rapidly control infections and is valuable in the clinic (P > .05).
C1 [Gu, Xiang; Chen, Wei; Yuan, Kun; Tan, Jian; Sun, Suguang] Huazhong Univ Sci & Technol, Cent Hosp Wuhan, Tongji Med Coll, Dept Otolaryngol Head & Neck Surg, 26 Shengli St, Wuhan 430000, Peoples R China.
C3 Huazhong University of Science & Technology
RP Sun, SG (通讯作者)，Huazhong Univ Sci & Technol, Cent Hosp Wuhan, Tongji Med Coll, Dept Otolaryngol Head & Neck Surg, 26 Shengli St, Wuhan 430000, Peoples R China.
EM 250971686@qq.com
FU Hubei Special Fund for Knowledge Innovation [2017CFB558]
FX This research is funded by Hubei Special Fund for Knowledge Innovation.
   Project number: 2017CFB558.
CR Brito TP, 2017, BRAZ J OTORHINOLAR, V83, P341, DOI 10.1016/j.bjorl.2016.04.004
   Chen S, 2019, Zhonghua Shao Shang Za Zhi, V35, P608, DOI 10.3760/cma.j.issn.1009-2587.2019.08.010
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   Cramer JD, 2016, LARYNGOSCOPE, V126, P1753, DOI 10.1002/lary.25835
   Farmahan S, 2015, SURG-J R COLL SURG E, V13, P316, DOI 10.1016/j.surge.2014.02.006
   Hansen BW, 2020, SEMIN ULTRASOUND CT, V41, P74, DOI 10.1053/j.sult.2019.10.001
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   Hu Chenghao, 2018, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V32, P1061, DOI 10.7507/1002-1892.201802024
   Huang Q, 2019, J FOOT ANKLE SURG, V58, P954, DOI 10.1053/j.jfas.2018.12.020
   Lawrence R, 2017, CLIN OTOLARYNGOL, V42, P156, DOI 10.1111/coa.12692
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   Zhang Fl, 2019, MEDICINE, V98, DOI 10.1097/MD.0000000000018027
NR 20
TC 11
Z9 15
U1 0
U2 8
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD FEB 5
PY 2021
VL 100
IS 5
AR e24367
DI 10.1097/MD.0000000000024367
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA QB6GS
UT WOS:000614237200071
PM 33592884
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ito, E
   Yoshida, M
   Ohdaira, H
   Nakashima, K
   Suzuki, N
   Imakita, T
   Tsutsui, N
   Kitajima, M
   Suzuki, Y
AF Ito, E.
   Yoshida, M.
   Ohdaira, H.
   Nakashima, K.
   Suzuki, N.
   Imakita, T.
   Tsutsui, N.
   Kitajima, M.
   Suzuki, Y.
TI NEGATIVE PRESSURE WOUND THERAPY FOR SURGICAL SITE INFECTION AFTER
   DIGESTIVE SURGERY
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Ito, E.; Yoshida, M.; Ohdaira, H.; Nakashima, K.; Suzuki, N.; Imakita, T.; Tsutsui, N.; Kitajima, M.; Suzuki, Y.] Int Univ Hlth & Welf Hosp, Dept Surg, Otawara, Tochigi, Japan.
C3 International University of Health & Welfare
RI Yoshida, Masashi/ABG-7085-2021
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV-DEC
PY 2016
VL 24
IS 6
MA T-23
BP A6
EP A6
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA EI9JV
UT WOS:000392825000025
DA 2026-07-24
ER

PT J
AU Schaum, KD
AF Schaum, Kathleen D.
TI Disposable Negative-Pressure Wound Therapy Reimbursement Simplified for
   Home Health Agencies
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
C1 [Schaum, Kathleen D.] Kathleen D Schaum & Associates Inc, Lake Worth, FL USA.
   [Schaum, Kathleen D.] 6491 Rock Creek Dr, Lake Worth, FL 33467 USA.
C3 Kathleen D. Schaum & Associates
RP Schaum, KD (通讯作者)，6491 Rock Creek Dr, Lake Worth, FL 33467 USA.
EM kathleendschaum@bellsouth.net
CR Centers for Medicare & Medicaid Services, 2024, HOME HLTH CONSOLIDAT
   Department of Health and Human Services Centers for Medicare & Medicaid Services, 2024, HOME HLTH PROSPECTIV
NR 2
TC 0
Z9 1
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD FEB
PY 2024
VL 37
IS 2
BP 65
EP 66
DI 10.1097/ASW.0000000000000100
PG 2
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA FQ1X8
UT WOS:001147234700005
PM 38241448
DA 2026-07-24
ER

PT J
AU Brunette, G
   Ross, J
   Lee, LW
   Cina, R
AF Brunette, Glenda
   Ross, Julie
   Lee, Lara Wine
   Cina, Robert
TI NEGATIVE PRESSURE WOUND THERAPY AND PEDIATRIC PYODERMA GANGRENOSUM: AN
   UNLIKELY COMBINATION
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Brunette, Glenda] Quality, Charleston, SC USA.
   [Ross, Julie] Wound Care, Charleston, SC USA.
   [Lee, Lara Wine] Dermatology, Charleston, SC USA.
   [Cina, Robert] Pediat Surg, Charleston, SC USA.
EM brunette@musc.edu; rossje@musc.edu; winelee@musc.edu; cina@musc.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2019
VL 46
SU 3
MA PI09
BP S28
EP S28
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA IH1JR
UT WOS:000474247600067
DA 2026-07-24
ER

PT J
AU Wagner, WD
   Liu, J
   Morykwas, M
   Argenta, L
AF Wagner, William D.
   Liu, Jie
   Morykwas, Michael
   Argenta, Louis
TI Biodegradable polymers useful in wound repair requiring negative
   pressure wound therapy
SO FASEB JOURNAL
LA English
DT Meeting Abstract
C1 [Wagner, William D.; Liu, Jie; Morykwas, Michael; Argenta, Louis] Wake Forest Univ, Bowman Gray Sch Med, Winston Salem, NC USA.
C3 Wake Forest University; Wake Forest Baptist Medical Center
NR 0
TC 0
Z9 0
U1 0
U2 1
PU FEDERATION AMER SOC EXP BIOL
PI BETHESDA
PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA
SN 0892-6638
J9 FASEB J
JI Faseb J.
PD APR
PY 2009
VL 23
MA 469.7
PG 1
WC Biochemistry & Molecular Biology; Biology; Cell Biology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other
   Topics; Cell Biology
GA V27OC
UT WOS:000208621505480
DA 2026-07-24
ER

PT J
AU Argo, R
AF Argo, Rosie
TI Necrotizing Enterocolitis in a Neonate A Case Study Using Negative
   Pressure Wound Therapy
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE abdominal wall defects; negative pressure wound therapy neonates;
   negative pressure wound therapy; neonate necrotizing enterocolitis
ID MANAGEMENT
AB BACKGROUND: Necrotizing enterocolitis (NEC) is a disease of the intestine detrimental that occurs in approximately 10% of neonates who weigh 1500 g or less; it is associated with a 25% mortality rate. Additional abdominal wall defects and disturbance of environmental surroundings further compromise the likelihood of mortality. Early intervention and aggressive surgical treatment have been shown to decrease the mortality rate of this disease process.
   CASE STUDY: This case study describes wound and ostomy management on a neonate with NEC who, after bowel perforation, required a distal and proximal jejunostomy and a colostomy. Frequent dressing changes were disrupting the neonates' environmental factors that affect growth. Management began with an alginate dressing, but it was unsuccessful in containing the drainage. Negative pressure wound therapy was then applied to eliminate exudate and infectious material, control odor, and decrease environmental factors affecting growth, as well as to assist in wound closure.
   CONCLUSION: Necrotizing enterocolitis and potential complications such as perforation and dehiscence can be devastating for hospitalized neonates. In this case, negative pressure wound therapy promoted tissue growth and managed exudate and odor, while decreasing intervals between dressing changes. The abdominal wound healed, allowing for a better plane for stoma pouching. The neonate's ostomies were successfully reversed and he continues to thrive to date.
C1 Banner Estrella Med Ctr, Phoenix, AZ 85037 USA.
C3 Banner Research; Banner Health; Banner Estrella Medical Center
RP Argo, R (通讯作者)，Banner Estrella Med Ctr, 9201 West Thomas Rd, Phoenix, AZ 85037 USA.
EM Rosie.argo@bannerhealth.com
CR Altimier L, 2003, COMPREHENSIVE NEONAT, p[229, 20]
   Borgquist O, 2011, OSTOMY WOUND MANAG, V57, P44
   Bryant PA, 2004, NAT REV IMMUNOL, V4, P457, DOI 10.1038/nri1369
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   Razmus IS, 2011, J WOUND OSTOMY CONT, V38, P22, DOI [10.1097/WON.0b013e318202abdd, 10.1097/WON.0b013e3181fee6e9]
NR 5
TC 2
Z9 3
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2014
VL 41
IS 3
BP 222
EP 225
DI 10.1097/WON.0000000000000033
PG 4
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA AH9ZN
UT WOS:000336505400006
PM 24805173
DA 2026-07-24
ER

PT J
AU Vaz, TP
   Silva, AC
   Pestana, M
   Silva, CM
   Lopes, TA
   Silva, JA
AF Vaz, T. Pina
   Silva, A. Costa
   Pestana, M.
   Silva, C. Martins
   Lopes, T. Antunes
   Silva, J. Alturas
TI Negative prEssure Wound thErapy in Renal transplant (NEWER
   study)-preliminary results
SO EUROPEAN UROLOGY
LA English
DT Meeting Abstract
C1 [Vaz, T. Pina; Silva, A. Costa; Silva, C. Martins; Lopes, T. Antunes; Silva, J. Alturas] Ctr Hosp Univ Sao Joao, Dept Urol, Porto, Portugal.
   [Pestana, M.] Ctr Hosp Univ Sao Joao, Dept Nephrol, Porto, Portugal.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 0302-2838
EI 1873-7560
J9 EUR UROL
JI Eur. Urol.
PD MAR
PY 2025
VL 87
SU 2
MA P175
PG 202
WC Urology & Nephrology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Urology & Nephrology
GA 7SQ8C
UT WOS:001578717000165
DA 2026-07-24
ER

PT J
AU Niezgoda, JA
AF Niezgoda, JA
TI Combining negative pressure wound therapy with other wound management
   modalities
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article; Proceedings Paper
CT National Vacuum-Assisted Closure Education Conference
CY NOV 05-07, 2004
CL Los Angeles, CA
ID EXPRESSION
RI /AAV-2360-2021
CR Banwell P E, 1999, J Wound Care, V8, P79
   Buras JA, 2000, AM J PHYSIOL-CELL PH, V278, pC292, DOI 10.1152/ajpcell.2000.278.2.C292
   Hyperbaric Medical Solutions, Cardiology and Oxygen Therapy|Hyperbaric Medical Solutions
   KINDWALL EP, 1995, HYPERBARIC MED PRACT
   KNIGHTON DR, 1983, SCIENCE, V221, P1283, DOI 10.1126/science.6612342
   KNIGHTON DR, 1948, SOFT HARD TISSUE REP, P41
   MORYKWAS MJ, 1998, WOUND HEALING SOC NE, V8, P4
   Niezgoda JA, 1997, PLAST RECONSTR SURG, V99, P1620, DOI 10.1097/00006534-199705000-00023
   NIEZGODA JA, 2000, HYPERBARIC MED TODAY, V1, P10
   NIEZGODA JA, IN PRESS J PLAST REC
   PIERSON T, UNPUB EFFECTS LOW FR
NR 11
TC 3
Z9 8
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD FEB
PY 2005
SU S
BP 36S
EP 38S
PG 3
WC Dermatology; Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 906AP
UT WOS:000227613200008
DA 2026-07-24
ER

PT J
AU Winter, D
AF Winter, D
TI Perspectives on vacuum-assisted closure therapy in pilonidal sinus
   surgery
SO DISEASES OF THE COLON & RECTUM
LA English
DT Letter
CR Duxbury M S, 2003, J Wound Care, V12, P355
   Lynch JB, 2004, DIS COLON RECTUM, V47, P929, DOI 10.1007/s10350-004-0522-2
   McGuinness JG, 2003, DIS COLON RECTUM, V46, P274, DOI 10.1007/s10350-004-6535-z
   Schaffzin DM, 2004, DIS COLON RECTUM, V47, P1745, DOI 10.1007/s10350-004-0633-9
NR 4
TC 3
Z9 8
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013 USA
SN 0012-3706
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD SEP
PY 2005
VL 48
IS 9
BP 1829
EP 1829
DI 10.1007/s10350-005-0109-6
PG 1
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 958HT
UT WOS:000231436000025
PM 15981070
DA 2026-07-24
ER

PT J
AU Huan, NC
   Arifin, NM
   Khoo, TS
   Lai, YC
AF Huan, Nai Chien
   Arifin, Noorasyikin Mohamed
   Khoo, Teng Shin
   Lai, Yean Chen
TI MANAGEMENT OF MASSIVE SUBCUTANEOUS EMPHYSEMA USING NEGATIVE PRESSURE
   WOUND THERAPY DRESSINGS
SO RESPIROLOGY
LA English
DT Meeting Abstract
C1 [Huan, Nai Chien; Arifin, Noorasyikin Mohamed; Khoo, Teng Shin; Lai, Yean Chen] Labuan Hosp, Dept Internal Med, Labuan, Malaysia.
RI Huan, Nai-Chien/AAU-2503-2021
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1323-7799
EI 1440-1843
J9 RESPIROLOGY
JI Respirology
PD NOV
PY 2019
VL 24
SU 2
MA AP1037
BP 218
EP 218
PG 1
WC Respiratory System
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System
GA LK9DC
UT WOS:000531157100519
DA 2026-07-24
ER

PT J
AU Fukuda, S
   Nakano, M
   Kusumoto, K
   Miyake, Y
AF Fukuda, S.
   Nakano, M.
   Kusumoto, K.
   Miyake, Y.
TI ADVANTAGE AND DISADVANTAGE OF OUR OWN METHOD - NEGATIVE PRESSURE WOUND
   THERAPY
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Fukuda, S.; Nakano, M.] Iseikai Hosp, Plast Surg Aesthet Surg, Wound Healing Ctr, Osaka, Japan.
   [Kusumoto, K.] Kansai Med Univ Hosp, Plast Surg, Osaka, Japan.
   [Miyake, Y.] Yao Municipal Hosp, Plast Surg, Yao, Osaka, Japan.
C3 Kansai Medical University
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JAN-FEB
PY 2015
VL 23
IS 1
MA T6-01
BP A6
EP A7
PG 2
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA CH0DP
UT WOS:000353689600029
DA 2026-07-24
ER

PT J
AU Berger, RE
AF Berger, Richard E.
TI Fournier's Gangrene: Vacuum-Assisted Closure Versus Conventional
   Dressings Comment
SO JOURNAL OF UROLOGY
LA English
DT Editorial Material
NR 0
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0022-5347
J9 J UROLOGY
JI J. Urol.
PD JAN
PY 2010
VL 183
IS 1
BP 182
EP 182
DI 10.1016/j.juro.2009.09.048
PG 1
WC Urology & Nephrology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Urology & Nephrology
GA 531FO
UT WOS:000272649300069
DA 2026-07-24
ER

PT J
AU Brauns, B
   Schön, MP
   Zutt, M
AF Brauns, Birka
   Schoen, Michael P.
   Zutt, Markus
TI Ulcerative necrobiosis lipoidica successfully treated by vacuum-assisted
   closure therapy
SO EUROPEAN JOURNAL OF DERMATOLOGY
LA English
DT Letter
C1 [Brauns, Birka; Schoen, Michael P.] Univ Gottingen, Dept Dermatol, D-37075 Gottingen, Germany.
   [Zutt, Markus] Klinikum Bremen Mitte, Dept Dermatol, Bremen, Germany.
C3 University of Gottingen; Klinikum Bremen-Mitte
RP Brauns, B (通讯作者)，Univ Gottingen, Dept Dermatol, Robert Koch Str 40, D-37075 Gottingen, Germany.
EM b.brauns@med.uni-goettingen.de
OI Schön, Michael/0000-0002-0698-4130
CR Eberle FC, 2010, ACTA DERM-VENEREOL, V90, P104, DOI 10.2340/00015555-0757
   Hu SW, 2009, ARCH DERMATOL, V145, P437, DOI 10.1001/archdermatol.2009.6
   Negosanti L, 2010, EUR J DERMATOL, V20, P501, DOI 10.1684/ejd.2010.0964
   Suárez-Amor O, 2010, DERMATOLOGY, V221, P117, DOI 10.1159/000314694
   Zutt M, 2007, DERMATOLOGY, V214, P319, DOI 10.1159/000100882
NR 5
TC 4
Z9 5
U1 0
U2 4
PU JOHN LIBBEY EUROTEXT LTD
PI MONTROUGE
PA 127 AVE DE LA REPUBLIQUE, 92120 MONTROUGE, FRANCE
SN 1167-1122
J9 EUR J DERMATOL
JI Eur. J. Dermatol.
PD SEP-OCT
PY 2011
VL 21
IS 5
BP 791
EP 792
DI 10.1684/ejd.2011.1445
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 848AE
UT WOS:000297017400035
PM 21700546
DA 2026-07-24
ER

PT J
AU Fritze, F
   Hollerbuhl, H
   Gellert, K
AF Fritze, F
   Hollerbuhl, H
   Gellert, K
TI Vacuum assisted closure system in treatment of small bowel fistula
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nuernberg, GERMANY
C1 Oskar Ziethen Krankenhaus, Sana Klinikum Lichtenberg, Klin Allgemein & Viszeralchirurg, D-10365 Berlin, Germany.
RP Fritze, F (通讯作者)，Oskar Ziethen Krankenhaus, Sana Klinikum Lichtenberg, Klin Allgemein & Viszeralchirurg, Fanningerstr 32, D-10365 Berlin, Germany.
EM Fraukefritze@aol.com
NR 0
TC 1
Z9 1
U1 0
U2 0
PU JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
PI STUTTGART
PA RUEDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S105
EP S107
DI 10.1055/s-2006-921494
PG 3
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 034DB
UT WOS:000236904100024
PM 16575657
DA 2026-07-24
ER

PT J
AU Timmer, AS
   Zwanenburg, PR
   Boermeester, MA
AF Timmer, Allard S.
   Zwanenburg, Pieter R.
   Boermeester, Marja A.
TI Comment on "Prophylactic Negative Pressure Wound Therapy for Closed
   Laparotomy Incisions''
SO ANNALS OF SURGERY
LA English
DT Letter
C1 [Timmer, Allard S.; Zwanenburg, Pieter R.; Boermeester, Marja A.] Amsterdam UMC, Dept Surg, Locat AMC, Amsterdam, Netherlands.
C3 University of Amsterdam
RP Boermeester, MA (通讯作者)，Amsterdam UMC, Dept Surg, Locat AMC, Amsterdam, Netherlands.
EM m.a.boermeester@amsterdamumc.nl
OI Boermeester, Marja/0000-0003-3890-8105
CR [Anonymous]
   Bowater RJ, 2009, ANN SURG, V249, P551, DOI 10.1097/SLA.0b013e318199f202
   Guyatt GH, 2011, J CLIN EPIDEMIOL, V64, P1283, DOI 10.1016/j.jclinepi.2011.01.012
   Kuper TM, 2020, ANN SURG, V271, P67, DOI 10.1097/SLA.0000000000003435
   Zwanenburg PR, 2019, ANN SURG
NR 5
TC 0
Z9 0
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0003-4932
EI 1528-1140
J9 ANN SURG
JI Ann. Surg.
PD DEC
PY 2021
VL 274
IS 6
BP E716
EP E717
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WX3XK
UT WOS:000718532600094
PM 32502080
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Smith, J
AF Smith, Joshua
TI DETERMINING PROPERTIES OF WOUND DRESSINGS FOR NEGATIVE PRESSURE WOUND
   THERAPY (NPWT)
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Smith, Joshua] Vanderbilt Univ, Pioneer Technol, Dept Biomed Engn, Franklin, TN USA.
C3 Vanderbilt University
EM josh.smith@pioneertechnology1.com
CR BORGQUIST O, PLAST RECON IN PRESS
   Ljungh A, 2006, J Wound Care, V15, P175
   Smith J, 2010, METHOD DRESSING WOUN
NR 3
TC 0
Z9 0
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2012
VL 39
IS 3
SU S
MA 6416
BP S68
EP S68
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 948MP
UT WOS:000304507600201
DA 2026-07-24
ER

PT J
AU Elsass, F
AF Elsass, Ferne
TI SINGLE-USE NEGATIVE PRESSURE WOUND THERAPY SYSTEM AND THE PEDIATRIC
   PATIENT
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
EM ferne.elsass@chkd.org
CR Bryant R.A., 2012, Acute chronic wounds: Current management concepts
NR 1
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2019
VL 46
SU 3
MA eCS38
BP S21
EP S21
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA IH1JR
UT WOS:000474247600049
DA 2026-07-24
ER

PT J
AU Vijayan, R
   Singh, P
   Mosahebi, A
AF Vijayan, Roshan
   Singh, Prateush
   Mosahebi, Afshin
TI Single use negative-pressure wound therapy: Are we being sucked in?
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Letter
C1 [Vijayan, Roshan; Singh, Prateush; Mosahebi, Afshin] Royal Free Hosp, Dept Plast Surg, London NW3 2QG, England.
C3 University of London; University College London; Royal Free London NHS
   Foundation Trust; UCL Medical School
RP Vijayan, R (通讯作者)，Royal Free Hosp, Dept Plast Surg, London NW3 2QG, England.
EM Roshan.vijayan@gmail.com; Singh.prateush@gmail.com; a.mosahebi@ucl.ac.uk
OI Singh, Prateush/0000-0001-9904-1299
CR NICE, 2018, PICO NEG PRESS WOUND
   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Tanaydin V, 2018, AESTHET PLAST SURG, V42, P927, DOI 10.1007/s00266-018-1095-0
NR 4
TC 0
Z9 0
U1 0
U2 1
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD FEB
PY 2019
VL 72
IS 2
BP 344
EP 345
DI 10.1016/j.bjps.2018.10.034
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HI1EN
UT WOS:000456187300028
PM 30467001
DA 2026-07-24
ER

PT J
AU Cindass, R
   Wu, KY
   Lawson, SD
   Gorantla, VS
   Davis, MR
AF Cindass, Renford, Jr.
   Wu, Kevin Y.
   Lawson, Sharon D.
   Gorantla, Vijay S.
   Davis, Michael R.
TI A Novel Bioresorbable/Biointegratable/Biocompatible Dressing for
   Negative Pressure Wound Therapy
SO BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
CT International Surgical Congress of the
   Association-of-Surgeons-of-Great-Britain-and-Ireland
CY 2016
CL Belfast, IRELAND
SP Assoc Surg Great Britain & Ireland
C1 [Cindass, Renford, Jr.; Wu, Kevin Y.; Lawson, Sharon D.; Davis, Michael R.] RESTORTM Program, Afb, TX USA.
   [Cindass, Renford, Jr.] San Antonio Mil Med Ctr, Jbsa Ft Sam Houston, TX USA.
   [Lawson, Sharon D.] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA.
   [Gorantla, Vijay S.] Univ Pittsburgh, Med Ctr, Pittsburgh, PA USA.
   [Davis, Michael R.] US Army Inst Surg Res, Jbsa Ft Sam Houston, TX USA.
C3 Brooke Army Medical Center; University of Texas System; University of
   Texas at San Antonio; Pennsylvania Commonwealth System of Higher
   Education (PCSHE); University of Pittsburgh; United States Department of
   Defense; United States Army
RI Davis, Michael/PKR-9961-2026; Wu, Kevin Yang/AAY-8121-2020
NR 0
TC 0
Z9 0
U1 0
U2 2
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0007-1323
EI 1365-2168
J9 BRIT J SURG
JI Br. J. Surg.
PD AUG
PY 2016
VL 103
SU 6
SI SI
MA E033
BP 91
EP 91
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA DV9VF
UT WOS:000383289600288
DA 2026-07-24
ER

PT J
AU Holbert, MD
   Duff, J
   Wood, F
   Holland, AJA
   Teague, W
   Frear, C
   Crellin, D
   Phillips, N
   Storey, K
   Martin, L
   Singer, Y
   Dimanopoulos, TA
   Cuttle, L
   Vagenas, D
   McPhail, S
   Calleja, P
   De Young, A
   Kimble, RM
   Griffi, BR
AF Holbert, Maleea D.
   Duff, Jed
   Wood, Fiona
   Holland, Andrew J. A.
   Teague, Warwick
   Frear, Cody
   Crellin, Dianne
   Phillips, Natalie
   Storey, Kristen
   Martin, Lisa
   Singer, Yvonne
   Dimanopoulos, Tanesha A.
   Cuttle, Leila
   Vagenas, Dimitrios
   McPhail, Steven
   Calleja, Pauline
   De Young, Alexandra
   Kimble, Roy M.
   Griffi, Bronwyn R.
TI Barriers and co-designed strategies for the implementation of negative
   pressure wound therapy in acute pediatric burn care in Australia: A
   mixed method study
SO JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES
LA English
DT Article
DE Pediatric burn; Re-epithelialization; Negative pressure wound therapy;
   Implementation science; Implementation barriers
ID SUBATMOSPHERIC PRESSURE; PROGRESSION; EXPERIENCE; RECOMMENDATIONS;
   MANAGEMENT; DRESSINGS; PAIN; TIME
AB Purpose: Pediatric burn injuries are a global clinical issue causing significant morbidity . Early adjunctive negative pressure wound therapy improves re-epithelialization rates in children with burns, yet adoption in acute burn care is inconsistent. This investigation aimed to determine barriers to the implementation of adjunctive negative pressure wound therapy for the acute management of pediatric burns and co-design targeted implementation strategies. Methods: A sequential mixed methods design was used explore barriers to adjunctive negative pressure wound therapy implementation in acute pediatric burn care. An online questionnaire was disseminated to healthcare professionals within four major Australian pediatric hospitals, each with a dedicated burns service. Barriers were coded according to the Consolidated Framework for Implementation Research (CFIR). Semi-structured interviews with senior clinicians tailored implementation strategies to local contexts. A stakeholder consensus meeting consolidated implementation strategies and local processes. Results: Sixty-three healthcare professionals participated in the questionnaire, and semi-structured interviews involved nine senior burn clinicians. We identified eight implementation barriers across all five CFIR domains then co-designed targeted strategies to address identified barriers. Barriers included lack of available resources, limited access to knowledge and information, individual stage of change, patient needs and resources, limited knowledge and beliefs about the intervention, lack of external policies, intervention complexity, and poor implementation planning. Conclusion: Multiple contextual factors affect negative pressure wound therapy uptake in acute pediatric burn settings. Results will inform a multi-state stepped-wedge cluster randomized controlled trial. Additional resources, education, training, updated policies, and guidelines are required for successful implementation. It is anticipated that adjunctive negative pressure wound therapy, in conjunction with tailored implementation strategies, will enhance adoption and sustainability. Trial registration: Australian and New Zealand Clinical Trials Registry: ACTRN12622000166774. Registered 1 February 2022. Crown Copyright (c) 2024 Published by Elsevier Inc. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/).
C1 [Holbert, Maleea D.; Storey, Kristen; Singer, Yvonne; Dimanopoulos, Tanesha A.; Griffi, Bronwyn R.] Griffith Univ, Sch Nursing & Midwifery, Nathan Campus, Brisbane, Qld 4111, Australia.
   [Holbert, Maleea D.; Frear, Cody; Crellin, Dianne; Phillips, Natalie; Storey, Kristen; Dimanopoulos, Tanesha A.; De Young, Alexandra; Kimble, Roy M.; Griffi, Bronwyn R.] Childrens Hlth Queensland Hosp & Hlth Serv, South Brisbane, Qld 4101, Australia.
   [Duff, Jed] Queensland Univ Technol, Fac Hlth, Ctr Healthcare Transformat, Brisbane, Australia.
   [Wood, Fiona; Martin, Lisa] Perth Childrens Hosp, Nedlands, WA 6009, Australia.
   [Wood, Fiona; Martin, Lisa] Univ Western Australia, Burn Injury Res Unit, Crawley, WA 6009, Australia.
   [Holland, Andrew J. A.] Childrens Hosp Westmead, Burns Unit, Westmead, NSW 2145, Australia.
   [Holland, Andrew J. A.] Univ Sydney, Fac Med & Hlth, Sydney Med Sch, Sydney, NSW 2050, Australia.
   [Teague, Warwick] Murdoch Childrens Res Inst, Surg Res, Parkville, Vic 3052, Australia.
   [Teague, Warwick; Crellin, Dianne] Royal Childrens Hosp Melbourne, Burns Serv, Parkville, Vic 3052, Australia.
   [Teague, Warwick] Univ Melbourne, Dept Paediat, Parkville, Vic 3052, Australia.
   [Teague, Warwick] Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic 3004, Australia.
   [Frear, Cody] Univ Queensland, Fac Med, Brisbane, QLD 4006, Australia.
   [Crellin, Dianne] Univ Melbourne, Dept Nursing, Melbourne, Vic 3010, Australia.
   [Phillips, Natalie] Univ Queensland, Child Hlth Res Ctr, South Brisbane, Qld 4101, Australia.
   [Cuttle, Leila; Vagenas, Dimitrios] Queensland Univ Technol, Fac Hlth, Sch Biomed Sci, Brisbane, Australia.
   [McPhail, Steven] Queensland Univ Technol, Australian Ctr Hlth Serv Innovat, Sch Publ Hlth & Social Work, Kelvin Grove 4059, Australia.
   [McPhail, Steven] Queensland Univ Technol, Ctr Healthcare Transformat, Sch Publ Hlth & Social Work, Kelvin Grove 4059, Australia.
   [Calleja, Pauline] James Cook Univ, Coll Healthcare Sci, Cairns 4870, Australia.
C3 Griffith University; Childrens Health Queensland Hospital & Health
   Service; Queensland University of Technology (QUT); Perth Childrens
   Hospital; University of Western Australia; NSW Health; Sydney Childrens
   Hospitals Network; The Children's Hospital at Westmead; University of
   Sydney; University of Sydney; Murdoch Children's Research Institute;
   Royal Children's Hospital Melbourne; University of Melbourne; Monash
   University; University of Queensland; University of Melbourne;
   University of Queensland; Queensland University of Technology (QUT);
   Queensland University of Technology (QUT); Queensland University of
   Technology (QUT); James Cook University
RP Holbert, MD (通讯作者)，Griffith Univ, Sch Nursing & Midwifery, Nathan Campus, Brisbane, Qld 4111, Australia.
EM m.holbert@griffith.edu.au
RI Duff, Jed/AAV-9927-2020; Phillips, Natalie/LBI-7045-2024; De Young,
   Alex/D-9093-2019; Kimble, Roy/B-4160-2011; McPhail,
   Steven/JMR-2141-2023; Wood, Fiona/F-4703-2013; Cuttle,
   Leila/C-5223-2008; Teague, Warwick/AAY-7260-2020; Griffin,
   Bronwyn/AEB-6299-2022; Calleja, Pauline/AAE-7981-2020; fiona,
   wood/F-4703-2013; Singer, Yvonne/LEN-2822-2024
OI Duff, Jed/0000-0003-1427-0303; Holbert, Maleea/0000-0002-9902-5122;
   McPhail, Steven/0000-0002-1463-662X; Wood, Fiona/0000-0001-7397-4074;
   Cuttle, Leila/0000-0002-2282-4815; Teague, Warwick/0000-0003-4747-6025;
   Martin, Lisa Joanne/0000-0001-8947-834X; Griffin,
   Bronwyn/0000-0002-6182-9125; Calleja, Pauline/0000-0001-5674-1404;
   fiona, wood/0000-0001-5427-6588; Singer, Yvonne/0000-0001-6225-5891
FU National Health and Medical Research Council (NHMRC) Partnership
   Projects PRC2 [2006970]; National Health and Medical Research Council
   (NHMRC) [2006970] Funding Source: National Health and Medical Research
   Council (NHMRC)
FX This project has been awarded funding from the National Health and
   Medical Research Council (NHMRC) Partnership Projects PRC2 Funding ID:
   2006970.
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NR 60
TC 3
Z9 6
U1 0
U2 7
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0882-5963
J9 J PEDIATR NURS
JI J. Pediatr. Nurs.
PD JUL-AUG
PY 2024
VL 77
BP e520
EP e530
DI 10.1016/j.pedn.2024.05.018
EA JUL 2024
PG 11
WC Nursing; Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing; Pediatrics
GA YH3S6
UT WOS:001267564100001
PM 38762422
OA Green Published, Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Luster, S
   Johnson, D
   Beck, C
AF Luster, Stephanie
   Johnson, David
   Beck, Cassandra
TI Negative Pressure Wound Therapy: Wound Healing Complications via
   Retained Foreign Body
SO AMERICAN JOURNAL OF CLINICAL PATHOLOGY
LA English
DT Meeting Abstract
CT Annual Meeting of the American-Society-for-Clinical-Pathology (ASCP)
CY OCT 08-10, 2014
CL Tampa, FL
SP Amer Soc Clin Pathol
C1 [Luster, Stephanie; Johnson, David; Beck, Cassandra] Lake Erie Coll Osteopath Med, Bradenton, FL USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC CLINICAL PATHOLOGY
PI CHICAGO
PA 2100 W HARRISON ST, CHICAGO, IL 60612 USA
SN 0002-9173
EI 1943-7722
J9 AM J CLIN PATHOL
JI Am. J. Clin. Pathol.
PD OCT
PY 2014
VL 142
SU 1
MA 168
PG 1
WC Pathology
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Pathology
GA CO6ED
UT WOS:000359249100169
DA 2026-07-24
ER

PT J
AU Yermashkevich, S
   Petukhov, V
AF Yermashkevich, S.
   Petukhov, V.
TI Vacuum-Assisted Closure Therapy for the Management of Lung Abscess
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Yermashkevich, S.; Petukhov, V.] Vitebsk State Med Univ, Hosp Surg, Vitebsk, BELARUS.
C3 Vitebsk State Order of Peoples' Friendship Medical University
EM ermashkevich_sn@tut.by
NR 0
TC 0
Z9 0
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PD MAY
PY 2021
VL 203
SU _1
AR A3866
DI 10.1164/ajrccm-conference.2021.203.1_MeetingAbstracts.A3866
PG 1
WC Critical Care Medicine; Respiratory System
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Respiratory System
GA IQ7AN
UT WOS:001778050900007
OA gold
DA 2026-07-24
ER

PT J
AU Yermashkevich, S
   Petukhov, V
AF Yermashkevich, S.
   Petukhov, V.
TI Vacuum-Assisted Closure Therapy for the Management of Lung Abscess
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
CT International Conference of the American-Thoracic-Society (ATS)
CY MAY 14-19, 2021
CL ELECTR NETWORK
SP Amer Thorac Soc
C1 [Yermashkevich, S.; Petukhov, V.] Vitebsk State Med Univ, Hosp Surg, Vitebsk, BELARUS.
C3 Vitebsk State Order of Peoples' Friendship Medical University
EM ermashkevich_sn@tut.by
NR 0
TC 0
Z9 0
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PD MAY 1
PY 2021
VL 203
SU 1
MA A3866
PG 1
WC Critical Care Medicine; Respiratory System
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC General & Internal Medicine; Respiratory System
GA UA9IX
UT WOS:000685468903630
DA 2026-07-24
ER

PT J
AU Loske, G
   Müller, C
AF Loske, Gunnar
   Mueller, Christian
TI Endoscopic vacuum-assisted closure of upper intestinal anastomotic leaks
SO GASTROINTESTINAL ENDOSCOPY
LA English
DT Letter
ID SEPSIS
C1 [Loske, Gunnar; Mueller, Christian] Kathol Marienkrankenhaus GmbH, Dept Surg, Hamburg, Germany.
C3 St. Marien Hospital
RP Loske, G (通讯作者)，Kathol Marienkrankenhaus GmbH, Dept Surg, Hamburg, Germany.
CR Nagell CF, 2006, INT J COLORECTAL DIS, V21, P657, DOI 10.1007/s00384-005-0083-4
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Weidenhagen R, 2007, VISZERALCHIRURGIE, V42, P165, DOI 10.1055/s-2007-960720
   Weidenhagen R, 2006, ZBL CHIR, V131, pS115, DOI 10.1055/s-2006-921512
   Weidenhagen R, 2004, SHOCK, V21, P152, DOI 10.1097/00024382-200403001-00608
   Weidenhagen R, 2003, COLOR DIS, V5, P1, DOI DOI 10.1046/J.1463-1318.5.S2.1.X
NR 6
TC 34
Z9 40
U1 0
U2 2
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0016-5107
EI 1097-6779
J9 GASTROINTEST ENDOSC
JI Gastrointest. Endosc.
PD MAR
PY 2009
VL 69
IS 3
BP 601
EP 602
DI 10.1016/j.gie.2008.06.058
PN 1
PG 2
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA 416NF
UT WOS:000264012100049
PM 19231507
OA Bronze
DA 2026-07-24
ER

PT J
AU Orsini, JA
AF Orsini, JA
TI Use of vacuum-assisted closure for management of traumatic wounds
SO EQUINE VETERINARY EDUCATION
LA English
DT Article
C1 Univ Penn, Sch Vet Med, New Bolton Ctr, Philadelphia, PA 19104 USA.
C3 University of Pennsylvania
RP Orsini, JA (通讯作者)，Univ Penn, Sch Vet Med, New Bolton Ctr, Philadelphia, PA 19104 USA.
CR Gemeinhardt KD, 2005, EQUINE VET EDUC, V17, P27, DOI 10.1111/j.2042-3292.2005.tb00331.x
NR 1
TC 0
Z9 0
U1 0
U2 2
PU EQUINE VETERINARY JOURNAL LTD
PI NEWMARKET
PA GRASEBY HOUSE, ENXING ROAD, NEWMARKET CB8 0AU, SUFFOLK, ENGLAND
SN 0957-7734
J9 EQUINE VET EDUC
JI Equine Vet. Educ.
PD FEB
PY 2005
VL 17
IS 1
BP 33
EP 33
PG 1
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA 895JQ
UT WOS:000226857600009
OA Bronze
DA 2026-07-24
ER

PT J
AU Kalakish, SR
   Carbone, DJ
   Molnar, J
AF Kalakish, SR
   Carbone, DJ
   Molnar, J
TI Vacuum-assisted closure for the treatment of degloving penile injuries
SO JOURNAL OF UROLOGY
LA English
DT Meeting Abstract
CT Annual Meeting of the American-Urological-Association
CY MAY 20-25, 2006
CL Atlanta, GA
SP Amer Urolog Assoc
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0022-5347
J9 J UROLOGY
JI J. Urol.
PD APR
PY 2006
VL 175
IS 4
SU S
MA 302
BP 100
EP 100
DI 10.1016/S0022-5347(18)32569-2
PG 1
WC Urology & Nephrology
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Urology & Nephrology
GA 022EZ
UT WOS:000236039200303
DA 2026-07-24
ER

PT J
AU Menzies, S
   McGrath, E
   Wynne, B
   Ormond, P
   Barry, R
AF Menzies, S.
   McGrath, E.
   Wynne, B.
   Ormond, P.
   Barry, R.
TI Portable negative-pressure wound therapy for management of poorly
   healing wounds
SO BRITISH JOURNAL OF DERMATOLOGY
LA English
DT Meeting Abstract
CT 96th Annual Meeting of the British-Association-of-Dermatologist
CY JUL 05-07, 2016
CL Birmingham, ENGLAND
SP British Assoc Dermatologist
C1 [Menzies, S.; McGrath, E.; Wynne, B.; Ormond, P.; Barry, R.] St James Hosp, Dublin 8, Ireland.
C3 Trinity College Dublin
NR 0
TC 0
Z9 0
U1 0
U2 2
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0007-0963
EI 1365-2133
J9 BRIT J DERMATOL
JI Br. J. Dermatol.
PD JUL
PY 2016
VL 175
SU 1
SI SI
MA DS15
BP 113
EP 114
PG 2
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Dermatology
GA DR1FA
UT WOS:000379650200220
DA 2026-07-24
ER

PT J
AU Argo, R
AF Argo, Rosie
TI NEGATIVE PRESSURE WOUND THERAPY: A CASE STUDY ON NEONATE NECROTIZING
   ENTEROCOLITIS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Argo, Rosie] BEMC, Phoenix, AZ USA.
EM rosie.argo@bannerhealth.com
CR Eichel M, 2009, DEV SUPPORTIVE CARE
   Kurichi JE, 2012, AM J PHYS MED REHABI
   Molan P C, 2006, Int J Low Extrem Wounds, V5, P40, DOI 10.1177/1534734605286014
   Peterson M, 2011, 12 NPUAP BIENN C LAS
   Pieper B, 2009, J WOUND OSTOMY CONT, V36, P60, DOI 10.1097/01.WON.0000345177.58740.7d
   Robson V, 2012, BRIT J ORAL MAX SURG, V50, P321, DOI 10.1016/j.bjoms.2011.07.014
NR 6
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2013
VL 40
SU 3
MA 1438
BP S20
EP S21
PG 2
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 300KD
UT WOS:000330461900054
DA 2026-07-24
ER

PT J
AU Fan, L
   Luo, H
   Liu, B
   Fa, XN
   Liu, T
   Ma, C
AF Fan, Lei
   Luo, Huan
   Liu, Bing
   Fa, Xianen
   Liu, Tao
   Ma, Chao
TI Clinical treatment of diabetic foot ulcer combined with Budd-Chiari
   syndrome A case report
SO MEDICINE
LA English
DT Article
DE Budd-Chiari syndrome; clinical practice; debridement; diabetic foot
   ulcer; foam dressing; moist healing; vacuum sealing drainage
ID MOIST
AB Rationale: Diabetic foot ulcer is a severe complication of diabetes, and most patients with diabetic foot ulcer require amputation. The incidence of Budd-Chiari syndrome is low; it is relatively rare. Diabetic foot ulcer combined with Budd-Chiari syndrome has not been reported so far.
   Patient concerns: A 52-year-old man presented with uncontrolled high body temperature, continued expansion of the lower leg and foot ulcer with increasing malodor.
   Diagnosis: The patient was diagnosed with Wagner grade 4 diabetic foot ulcer combined with Budd-Chiari syndrome.
   Interventions: Critical treatment was performed immediately after his admission to the hospital. After the patient's condition was stable, we performed an interventional procedure to relieve the inferior vena cava obstruction. Debridement was then performed on the diabetic foot ulcer. Finally, skin grafting was performed due to condition of the wound. We completed moist healing and vacuum sealing drainage throughout the treatment process.
   Outcomes: The patient was hospitalized for 56 days, and all his right lower extremity ulcers eventually healed.
   Lessons: In the treatment of diabetic foot ulcer combined with Budd-Chiari syndrome, it is necessary to develop a unified treatment plan that includes the timely treatment of Budd-Chiari syndrome upon admission, the strategic use of debridement, and the application of moist healing and vacuum sealing drainage.
C1 [Fan, Lei; Liu, Tao; Ma, Chao] Zhengzhou Univ, Peoples Hosp, Henan Prov Peoples Hosp, Dept Orthoped Surg, Zhengzhou, Henan, Peoples R China.
   [Luo, Huan] Charite Univ Med Berlin, Dept Ophthalmol, Campus Virchow, Berlin, Germany.
   [Luo, Huan] Zhengzhou Univ, Peoples Hosp, Henan Prov Peoples Hosp, Dept Ophthalmol, Zhengzhou, Henan, Peoples R China.
   [Liu, Bing; Fa, Xianen; Ma, Chao] Zhengzhou Univ, Affiliated Hosp 2, Dept Cardiovasc Surg, Zhengzhou, Henan, Peoples R China.
   [Ma, Chao] Charite Univ Med Berlin, Dept Cardiol, Campus Virchow, Berlin, Germany.
   [Ma, Chao] German Ctr Cardiovasc Res DZHK, Partner Site Berlin, Berlin, Germany.
C3 Zhengzhou University; Free University of Berlin; Humboldt University of
   Berlin; Charite Universitatsmedizin Berlin; Zhengzhou University;
   Zhengzhou University; Free University of Berlin; Humboldt University of
   Berlin; Charite Universitatsmedizin Berlin; German Centre for
   Cardiovascular Research
RP Ma, C (通讯作者)，Charite Univ Med Berlin, Berlin, Germany.
EM chao.ma@charite.de
RI Ma, Chao/HLQ-3961-2023
OI Ma, Chao/0000-0003-1444-4668
FU Zhengzhou University Overseas Virtual Research Institute Special Fund,
   Zhengzhou University
FX This study was funded by Zhengzhou University Overseas Virtual Research
   Institute Special Fund, Zhengzhou University.
CR Amer Diabet Assoc, 2018, DIABETES CARE, V41, pS55, DOI 10.2337/dc18-S006
   Anghel EL, 2016, PLAST RECONSTR SURG, V138, p82S, DOI 10.1097/PRS.0000000000002651
   Boateng J, 2015, J PHARM SCI-US, V104, P3653, DOI 10.1002/jps.24610
   Clark N, 2003, DIABETES CARE, V26, P3333
   Gethin G., 2015, COCHRANE DB SYST REV, V9
   Junker JPE, 2013, ADV WOUND CARE, V2, P348, DOI 10.1089/wound.2012.0412
   Korting HC, 2011, J EUR ACAD DERMATOL, V25, P130, DOI 10.1111/j.1468-3083.2010.03775.x
   Pemayun TGD, 2015, DIABET FOOT ANKLE, V6, DOI 10.3402/dfa.v6.29629
   Rajani R, 2009, LIVER INT, V29, P253, DOI 10.1111/j.1478-3231.2008.01838.x
   Singh N, 2005, JAMA-J AM MED ASSOC, V293, P217, DOI 10.1001/jama.293.2.217
   Xu B, 2017, Zhonghua Nei Ke Za Zhi, V56, P24, DOI 10.3760/cma.j.issn.0578-1426.2017.01.007
NR 11
TC 4
Z9 4
U1 1
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD JAN
PY 2019
VL 98
IS 4
AR e14224
DI 10.1097/MD.0000000000014224
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA HQ3FY
UT WOS:000462296900050
PM 30681600
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Yuan, XG
   Zhang, X
   Fu, YX
   Tian, XF
   Liu, Y
   Xiao, J
   Li, TW
   Qiu, L
AF Yuan, X. -g.
   Zhang, X.
   Fu, Y. -x.
   Tian, X. -f.
   Liu, Y.
   Xiao, J.
   Li, T. -w.
   Qiu, L.
TI Sequential therapy with "vacuum sealing drainage-artificial dermis
   implantation-thin partial thickness skin grafting" for deep and infected
   wound surfaces in children
SO ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH
LA English
DT Article
DE Vacuum sealing drainage; Artificial dermis; Thin partial thickness skin
   grafting; Children
ID MANAGEMENT; INJURY; TRIAL
AB Objective: To evaluate the efficacy of a "vacuum sealing drainage (VSD) - artificial dermis implantation (ADI) - thin partial thickness skin grafting (TSG)" sequential therapy for deep and infected wounds in children.
   Materials and methods: Fifty-three pediatric patients with deep and infected wounds were treated with sequential VSD-ADI-TSG therapy. The efficacy of this treatment was compared with that of the surgical debridement-change dressings-thin partial thickness skin grafting previously performed on 20 patients. Survival of tissue grafts, color and flexibility, subcutaneous fullness and scar formation of the graft site were examined and compared.
   Results: The sequential therapy combined the advantages of the VSD treatment, in reducing tissue necrosis and infection on the wound surfaces and promoting the growth of granulation tissue, with the enhancement of grafting by artificial dermis. Compared with the 20 controls, skin grafted on the artificial dermis was more smooth and glossy, while the textures of the region were more elastic, and the scars were significantly lighter in Vancouver scale.
   Conclusion: The sequential VSD-ADI-TSG therapy is a simple and effective treatment for children with deep and infected wounds.
   Level of evidence: IV. (c) 2016 Published by Elsevier Masson SAS.
C1 [Yuan, X. -g.; Fu, Y. -x.; Tian, X. -f.; Liu, Y.; Xiao, J.; Li, T. -w.; Qiu, L.] Chongqing Med Univ, Childrens Hosp, Dept Burns & Plast Surg, 136 Zhongshan 2nd Rd, Chongqing 400014, Peoples R China.
   [Yuan, X. -g.; Zhang, X.; Fu, Y. -x.; Tian, X. -f.; Liu, Y.; Xiao, J.; Li, T. -w.; Qiu, L.] Chongqing Int Sci & Technol Cooperat Ctr Child De, Minist Educ, Key Lab Child Dev & Disorders, Key Lab Pediat Chongqing CSTC2009CA5002, Chongqing, Peoples R China.
C3 Chongqing Medical University
RP Qiu, L (通讯作者)，Chongqing Med Univ, Childrens Hosp, Dept Burns & Plast Surg, 136 Zhongshan 2nd Rd, Chongqing 400014, Peoples R China.
EM qinlin118@126.com
RI ; zhang, xuan/HNQ-7981-2023
OI 张, 萱/0000-0002-5657-9424; 
CR [Anonymous], 2008, World Report on Child Injury Prevention
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   Feldmann ME, 2008, J CRANIOFAC SURG, V19, P942, DOI 10.1097/SCS.0b013e318175f38d
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Fleischmann W, 1997, UNFALLCHIRURG, V100, P301, DOI 10.1007/s001130050123
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   Stannard JP, 2010, INJURY, V41, P780, DOI 10.1016/j.injury.2009.08.011
   STERN R, 1990, Journal of Burn Care and Rehabilitation, V11, P7, DOI 10.1097/00004630-199001000-00003
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   Towner E, 2009, GLOB PUBLIC HEALTH, V4, P402, DOI 10.1080/17441690802449842
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Wang WY, 2014, EXP THER MED, V7, P1221, DOI 10.3892/etm.2014.1567
   Whelan C, 2005, J UROLOGY, V173, P1463, DOI 10.1097/01.ju.0000157339.05939.21
   Wyrzykowski D, 2015, BURNS, V41, P359, DOI 10.1016/j.burns.2014.07.009
   Yeong EK, 2013, J BURN CARE RES, V34, P161, DOI 10.1097/BCR.0b013e3182685f0a
NR 34
TC 14
Z9 20
U1 0
U2 11
PU ELSEVIER MASSON, CORPORATION OFFICE
PI PARIS
PA 65 CAMILLE DESMOULINS CS50083 ISSY-LES-MOULINEAUX, 92442 PARIS, FRANCE
SN 1877-0568
J9 ORTHOP TRAUMATOL-SUR
JI Orthop. Traumatol.-Surg. Res.
PD MAY
PY 2016
VL 102
IS 3
BP 369
EP 373
DI 10.1016/j.otsr.2016.01.020
PG 5
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA DK8EQ
UT WOS:000375160400016
PM 27038673
DA 2026-07-24
ER

PT J
AU Taets, GGC
AF Taets, Gunnar G. C., Sr.
TI VACUUM ASSISTED CLOSURE: A TECHNOLOGY USED BY THE NURSE SPECIALIST
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Taets, Gunnar G. C., Sr.] Fed Univ State Rio de Janeiro UNIRIO, Rio De Janeiro, Brazil.
C3 Universidade Federal do Estado do Rio de Janeiro
EM oenfermeiro2007@hotmail.com
RI /Q-1388-2019
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BERGESTROM N, 1987, NURS RES, V26, P205
   Bryant RA., 1992, Acute and chronics wounds nursing management, VFourth
   GUYNTON AC, 1981, FISIOLOGIA HUMANA, P84112
   *VAC, 2007, THER CLIN GUID REF S
NR 5
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2010
VL 37
IS 3
SU S
BP S52
EP S52
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 600RG
UT WOS:000278004200141
DA 2026-07-24
ER

PT J
AU Wedemeyer, J
   Manns, MP
AF Wedemeyer, Jochen
   Manns, Michael P.
TI Endoscopic vacuum-assisted closure of upper intestinal anastomotic leaks
   Response
SO GASTROINTESTINAL ENDOSCOPY
LA English
DT Letter
C1 [Wedemeyer, Jochen; Manns, Michael P.] Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany.
C3 Hannover Medical School
RP Wedemeyer, J (通讯作者)，Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany.
RI Manns, Michael/AFG-3063-2022
CR Glitsch A, 2008, ENDOSCOPY, V40, P192, DOI 10.1055/s-2007-995384
   Nagell CF, 2006, INT J COLORECTAL DIS, V21, P657, DOI 10.1007/s00384-005-0083-4
   VANKOPEREN PJ, 2008, COLORECTAL DIS  0209, DOI DOI 10.1016/J.GIE.2008.08.020
   WEDEMEYER J, 2007, ENDOSKOPIE HEUTE, V20, P94
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
NR 6
TC 0
Z9 0
U1 0
U2 0
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0016-5107
EI 1097-6779
J9 GASTROINTEST ENDOSC
JI Gastrointest. Endosc.
PD MAR
PY 2009
VL 69
IS 3
BP 602
EP 602
DI 10.1016/j.gie.2008.08.020
PN 1
PG 1
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA 416NF
UT WOS:000264012100050
OA Bronze
DA 2026-07-24
ER

PT J
AU de Steur, W
   Steenvoorde, P
   van Doorn, L
   da Costa, SA
   Oskam, J
AF de Steur, W.
   Steenvoorde, P.
   van Doorn, L.
   da Costa, S. A.
   Oskam, J.
TI Vacuum-assisted closure (VAC) therapy in a home care setting
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [de Steur, W.; Steenvoorde, P.; da Costa, S. A.; Oskam, J.] Rijnland Med Ctr, Dept Surg, Leiderdorp, Netherlands.
   [Steenvoorde, P.; van Doorn, L.; Oskam, J.] Rijnland Wound Ctr, Leiderdorp, Netherlands.
C3 Rijnland Hospital
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 1067-1927
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV-DEC
PY 2007
VL 15
IS 6
BP A144
EP A144
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 232OR
UT WOS:000251029500111
DA 2026-07-24
ER

PT J
AU Khan, M
   Pestana, IA
   Bi, HD
AF Khan, Mija
   Pestana, Ivo A.
   Bi, Hongda
TI Use of Negative Pressure Wound Therapy in Fasciocutaneous Free-Tissue
   Transfer
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Meeting Abstract
CT Annual Clinical Congress of the American-College-of-Surgeons (ACS)
CY OCT 22-26, 2017
CL San Diego, CA
SP Amer Coll Surg
C1 Wake Forest Univ, Baptist Med Ctr, Winston Salem, NC 27109 USA.
   Shanghai Hosp, Shanghai, Peoples R China.
C3 Wake Forest University; Wake Forest Baptist Medical Center
RI Pestana, Ivo/JMR-2324-2023
NR 0
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD OCT
PY 2017
VL 225
IS 4
SU 1
BP S168
EP S168
DI 10.1016/j.jamcollsurg.2017.07.380
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA FK2MC
UT WOS:000413315300359
DA 2026-07-24
ER

PT J
AU Goncalves, V
AF Goncalves, Viviana
TI PREVENTION OF STERNOTOMY DEHISCENCE WITH NEGATIVE-PRESSURE WOUND THERAPY
   IN PAEDIATRICS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Goncalves, Viviana] Cardiothorac Surg, Porto, Portugal.
EM enf.vivianagoncalves@gmail.com
CR [Anonymous], 2016, CLOS SURG INC MAN UN
   Ciprandi G, 2018, J TISSUE VIABILITY, V27, P244, DOI 10.1016/j.jtv.2018.08.001
   Dohmen PM, 2014, MED SCI MONITOR, V20, P1814, DOI 10.12659/MSM.891169
   European Wound Management Association-EWMA Document, 2017, NEG PRESS WOUND THER
   Philip B, 2017, J WOUND CARE, V26, P491, DOI 10.12968/jowc.2017.26.8.491
NR 5
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2023
VL 50
IS 3
SU S
MA PI48
BP S40
EP S40
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA S6IO9
UT WOS:001072181900088
DA 2026-07-24
ER

PT J
AU Salgarello, M
   Tambasco, D
   Farallo, E
   Savino, G
   Bonomo, L
AF Salgarello, Marzia
   Tambasco, Damiano
   Farallo, Eugenio
   Savino, Giancarlo
   Bonomo, Lorenzo
TI New therapeutic horizons for the use of negative pressure wound therapy?
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Letter
C1 [Salgarello, Marzia; Tambasco, Damiano; Farallo, Eugenio] Univ Cattolica Sacro Cuore, Univ Hosp A Gemelli, Dept Plast & Reconstruct Surg, I-00168 Rome, Italy.
   [Savino, Giancarlo; Bonomo, Lorenzo] Univ Cattolica Sacro Cuore, Univ Hosp A Gemelli, Dept Radiol, I-00168 Rome, Italy.
C3 Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli;
   Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli
RP Tambasco, D (通讯作者)，Univ Cattolica Sacro Cuore, Univ Hosp A Gemelli, Dept Plast & Reconstruct Surg, Largo A Gemelli 8, I-00168 Rome, Italy.
EM damtam@hotmail.it
RI Salgarello, Marzia/GYJ-2938-2022; Tambasco, Damiano/GMX-2383-2022
OI Tambasco, Damiano/0000-0001-9119-6667
CR [Anonymous], 1926, Surg Gynecol Obstet
   Hauser CJ, 2008, CURRENT THERAPY TRAU, P269
   HUDSON TR, 1954, JAMA-J AM MED ASSOC, V156, P768, DOI 10.1001/jama.1954.02950080016007
   JASLOW IA, 1946, AM J SURG, V72, P753, DOI 10.1016/0002-9610(46)90358-3
   Nirula R, 2010, AM SURGEON, V76, P793
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
NR 7
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0020-1383
EI 1879-0267
J9 INJURY
JI Injury-Int. J. Care Inj.
PD NOV
PY 2011
VL 42
IS 11
BP 1388
EP 1390
DI 10.1016/j.injury.2011.03.060
PG 4
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA 841UN
UT WOS:000296540300041
PM 21514586
DA 2026-07-24
ER

PT J
AU Kostiuk, V
   Setia, O
   Cardella, J
   Strosberg, D
   Tonnessen, BH
   Guzman, RJ
   Aboian, E
AF Kostiuk, Valentyna
   Setia, Ocean
   Cardella, Jonathan
   Strosberg, David
   Tonnessen, Britt H.
   Guzman, Raul J.
   Aboian, Edouard
TI The Use of Negative Pressure Wound Therapy After Arterial Vascular
   Reconstructions
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Meeting Abstract
CT 36th Annual Meeting of the Eastern-Vascular-Society (EVS)
CY SEP 29-OCT 01, 2022
CL Philadelphia, PA
SP Eastern Vasc Soc
C1 [Kostiuk, Valentyna] Yale Univ, Sch Med, New Haven, CT USA.
   [Setia, Ocean; Cardella, Jonathan; Strosberg, David; Tonnessen, Britt H.; Guzman, Raul J.; Aboian, Edouard] Yale Univ, Div Vasc Surg & Endovasc Therapy, Dept Surg, Sch Med, New Haven, CT USA.
C3 Yale University; Yale University
RI Tonnessen, Britt/KIA-8309-2024
NR 0
TC 0
Z9 0
U1 0
U2 0
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
J9 J VASC SURG
JI J. Vasc. Surg.
PD SEP
PY 2022
VL 76
IS 3
MA 0667_0933_
BP E26
EP E27
PG 2
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery; Cardiovascular System & Cardiology
GA 4I8PB
UT WOS:000850835400027
DA 2026-07-24
ER

PT J
AU Asano, T
   Hirai, A
AF Asano, T.
   Hirai, A.
TI Pitfall of negative pressure wound therapy ∼ reconsideration of
   neagative pressure sytem
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Asano, T.; Hirai, A.] Fratern Mem Hosp, Div Plast Surg, Bengaluru, Karnataka, India.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD SEP
PY 2020
VL 28
IS 5
MA O2-1
BP A8
EP A8
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA NN7RN
UT WOS:000568983900025
DA 2026-07-24
ER

PT J
AU Schaum, KD
AF Schaum, Kathleen D.
TI Changing Misperceptions about Separate Billing for Disposable Negative
   Pressure Wound Therapy
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Editorial Material
C1 [Schaum, Kathleen D.] Kathleen Schaum & Associates Inc, Lake Worth, FL USA.
C3 Kathleen D. Schaum & Associates
RP Schaum, KD (通讯作者)，6491 Rock Creek Dr, Lake Worth, FL 33467 USA.
EM kathleendschaum@bellsouth.net
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD NOV
PY 2017
VL 30
IS 11
BP 524
EP 525
DI 10.1097/01.ASW.0000524613.69666.c9
PG 2
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA FQ7EH
UT WOS:000418525200009
PM 29049262
DA 2026-07-24
ER

EF