﻿FN Clarivate Analytics Web of Science
VR 1.0
PT J
AU Nair, D
   Banks, J
   Guy, R
AF Nair, Dheepa
   Banks, Jessica
   Guy, Richard
TI Active management of the open abdomen in non-trauma catastrophes,
   including use of negative pressure wound therapy, is associated with
   high primary fascial closure rates
SO BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
C1 [Nair, Dheepa; Banks, Jessica; Guy, Richard] Arrowe Pk Hosp, Emergency Surg Dept, Birkenhead, Merseyside, England.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BRIT J SURG
JI Br. J. Surg.
PD OCT
PY 2021
VL 108
SU 7
MA EP.FRI.337
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WR6RR
UT WOS:000714625800409
DA 2026-07-24
ER

PT J
AU Evans, SL
AF Evans, Susan L.
TI Does treatment of split-thickness skin grafts with negative-pressure
   wound therapy improve tissue markers of wound healing in a porcine
   experimental model? EDITORIAL CRITIQUE
SO JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
LA English
DT Editorial Material
C1 Carolinas Med Ctr, Dept Surg, Charlotte, NC 28203 USA.
C3 Carolinas Medical Center
RP Evans, SL (通讯作者)，Carolinas Med Ctr, Dept Surg, Charlotte, NC 28203 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 2163-0755
J9 J TRAUMA ACUTE CARE
JI J. Trauma Acute Care Surg.
PD AUG
PY 2012
VL 73
IS 2
BP 451
EP 451
PG 1
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Surgery
GA 992VG
UT WOS:000307807400040
DA 2026-07-24
ER

PT J
AU Li, J
   Wang, HY
   Yang, YF
   Wang, AN
   Shi, Y
   Cui, TB
AF Li, J.
   Wang, H. -Y.
   Yang, Y. -F.
   Wang, A. -N.
   Shi, Y.
   Cui, T. -B.
TI 撤稿声明: Efficacy of the Combination of Chinese Herbal Medicine and
   Negative Pressure Wound Therapy in the Treatment of Patients With
   Diabetic Foot Ulcer: A Meta-Analysis
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Retraction
CR Li J, 2024, INT WOUND J, V21, DOI 10.1111/iwj.14536
NR 1
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAR
PY 2025
VL 22
IS 3
AR e14536
DI 10.1111/iwj.70327
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA DA8BN
UT WOS:001679006300001
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Tedesco, BAN
   De Onofre, ALR
   de Amorim, PCH
   Lourencao, PLTD
   Ortolan, EVP
AF Tedesco, Bruna Aliotto Nalin
   De Onofre, Ana Luiza Rodakowski
   de Amorim, Paulo Cezar Haddad
   Lourencao, Pedro Luiz Toledo de Arruda
   Ortolan, Erika Veruska Paiva
TI Letter to the Editor in regard to: Vacuum-assisted closure (VAC)
   prevents wound dehiscence following posterior sagittal anorectoplasty
   (PSARP): An exploratory case-control study
SO JOURNAL OF PEDIATRIC SURGERY
LA English
DT Letter
C1 [Tedesco, Bruna Aliotto Nalin; De Onofre, Ana Luiza Rodakowski; de Amorim, Paulo Cezar Haddad; Lourencao, Pedro Luiz Toledo de Arruda; Ortolan, Erika Veruska Paiva] Botucatu Med Sch UNESP, Dept Surg & Orthoped, s-n Green Annex, BR-18618687 Botucatu, SP, Brazil.
RP Tedesco, BAN (通讯作者)，Botucatu Med Sch UNESP, Dept Surg & Orthoped, s-n Green Annex, BR-18618687 Botucatu, SP, Brazil.
EM brunalin@hotmail.com
RI ; de Arruda Lourenção, Pedro/AAH-1896-2021; /M-7258-2013; de Amorim,
   Paulo Cezar/AAZ-9258-2021
OI Tedesco, Bruna/0000-0002-3604-7762; 
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   de Jesus LE, 2018, J PEDIATR SURG, V53, P585, DOI 10.1016/j.jpedsurg.2017.11.048
   Martynov I, 2021, J PEDIATR SURG, V56, P745, DOI 10.1016/j.jpedsurg.2020.07.009
   Ritz LA, 2021, FRONT PEDIATR, V9, DOI 10.3389/fped.2021.727472
   Santosa KB, 2019, J SURG RES, V235, P560, DOI 10.1016/j.jss.2018.10.043
NR 5
TC 0
Z9 0
U1 0
U2 0
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0022-3468
EI 1531-5037
J9 J PEDIATR SURG
JI J. Pediatr. Surg.
PD JUN
PY 2022
VL 57
IS 6
BP 1174
EP 1176
DI 10.1016/j.jpedsurg.2021.12.009
EA MAY 2022
PG 3
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA 1V6II
UT WOS:000806190500022
PM 35027210
DA 2026-07-24
ER

PT J
AU Chandan, S
   Mohan, BP
   Khan, SR
   Malik, S
   Bhogal, N
   Chandan, OC
   Adler, DG
AF Chandan, Saurabh
   Mohan, Babu P.
   Khan, Shahab R.
   Malik, Sarah
   Bhogal, Neil
   Chandan, Ojasvini Choudhry
   Adler, Douglas G.
TI Clinical Efficacy of Endoscopic Vacuum-Assisted Closure Therapy (EVAC)
   in Gastroesophageal Defects: A Systematic Review and Comparative
   Meta-Analysis With Endoscopic Stent Therapy (EST)
SO AMERICAN JOURNAL OF GASTROENTEROLOGY
LA English
DT Meeting Abstract
CT Annual Scientific Meeting of the American-College-of-Gastroenterology
   (ACG)
CY OCT 25-30, 2019
CL San Antonio, TX
SP Amer Coll Gastroenterol
C1 [Chandan, Saurabh; Malik, Sarah; Bhogal, Neil; Chandan, Ojasvini Choudhry] Univ Nebraska Med Ctr, Omaha, NE USA.
   [Mohan, Babu P.; Khan, Shahab R.] Univ Arizona, Tucson, AZ USA.
   [Mohan, Babu P.; Khan, Shahab R.] Banner Univ, Med Ctr, Tucson, AZ USA.
   [Adler, Douglas G.] Univ Utah, Sch Med, Salt Lake City, UT USA.
C3 University of Nebraska System; University of Nebraska Medical Center;
   University of Arizona; Utah System of Higher Education; University of
   Utah
RI Chandan, Saurabh/M-9244-2019; Khan, Shahab/GSO-1694-2022
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0002-9270
EI 1572-0241
J9 AM J GASTROENTEROL
JI Am. J. Gastroenterol.
PD OCT
PY 2019
VL 114
SU S
MA 887
BP S514
EP S515
DI 10.14309/01.ajg.0000593084.69847.f6
PG 2
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Gastroenterology & Hepatology
GA KG2FF
UT WOS:000509756002108
DA 2026-07-24
ER

PT J
AU Song, J
   Liu, X
   Wu, T
AF Song, J.
   Liu, X.
   Wu, T.
TI 撤稿声明: Effectiveness of Prophylactic Application of Negative Pressure
   Wound Therapy in Stopping Surgical Site Wound Problems for Closed
   Incisions in Breast Cancer Surgery: A Meta-Analysis
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Retraction
CR Song JY, 2023, INT WOUND J, V20, P241, DOI 10.1111/iwj.13866
NR 1
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2025
VL 22
IS 4
AR e70459
DI 10.1111/iwj.70459
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA E9739
UT WOS:001623075600001
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ohta, K
   Danno, K
   Ota, H
   Matsumura, T
   Komori, T
   Okamura, S
   Okano, M
   Ogawa, A
   Tamagawa, H
   Sakata, K
   Noura, S
   Uemura, M
   Matsuda, C
   Mizushima, T
   Ikenaga, M
   Yamada, T
   Mori, M
   Doki, Y
AF Ohta, K.
   Danno, K.
   Ota, H.
   Matsumura, T.
   Komori, T.
   Okamura, S.
   Okano, M.
   Ogawa, A.
   Tamagawa, H.
   Sakata, K.
   Noura, S.
   Uemura, M.
   Matsuda, C.
   Mizushima, T.
   Ikenaga, M.
   Yamada, T.
   Mori, M.
   Doki, Y.
TI EFFICACY OF NEGATIVE PRESSURE WOUND THERAPY FOLLOWED BY DELAYED PRIMARY
   CLOSURE FOR THE ABDOMINAL WOUND IN PATIENTS WITH LOWER GASTROINTESTINAL
   PERFORATION: MULTI-CENTER PROSPECTIVE STUDY.
SO DISEASES OF THE COLON & RECTUM
LA English
DT Meeting Abstract
RI Mizushima, Tsunekazu/MSX-7856-2025
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD JUN
PY 2020
VL 63
IS 6
MA QS331
BP E122
EP E123
PG 2
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA LO8LL
UT WOS:000533877100091
DA 2026-07-24
ER

PT J
AU Frenda, G
   Baker, L
   Zhang, Y
   Nessim, C
AF Frenda, G.
   Baker, L.
   Zhang, Y.
   Nessim, C.
TI Use of a Skin Bridge Incision and Prophylactic Incisional Negative
   Pressure Wound Therapy Associated with Reduction in Surgical Site
   Infection Following Inguinal Lymph Node Dissection
SO ANNALS OF SURGICAL ONCOLOGY
LA English
DT Meeting Abstract
CT Society-of-Surgical-Oncology (SSO) International Conference on Surgical
   Cancer Care
CY MAR 25-28, 2020
CL Boston, MA
SP Soc Surg Oncol
C1 [Frenda, G.] McGill Univ, Gen Surg, Montreal Nord, PQ, Canada.
   [Baker, L.; Zhang, Y.; Nessim, C.] Univ Ottawa, Ottawa, ON, Canada.
C3 University of Ottawa
RI Nessim, Carolyn/AAH-8293-2019
NR 0
TC 0
Z9 0
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1068-9265
EI 1534-4681
J9 ANN SURG ONCOL
JI Ann. Surg. Oncol.
PD FEB
PY 2020
VL 27
IS SUPPL 1
SU 1
SI SI
MA 115
BP S48
EP S48
PG 1
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Oncology; Surgery
GA KU2TV
UT WOS:000519561700105
DA 2026-07-24
ER

PT J
AU Mueller, KB
   D'Antuono, M
   Patel, N
   Pivazyan, G
   Aulisi, EF
   Evans, KK
   Nair, MN
AF Mueller, Kyle B.
   D'Antuono, Matthew
   Patel, Nirali
   Pivazyan, Gnel
   Aulisi, Edward F.
   Evans, Karen K.
   Nair, M. Nathan
TI Effect of Incisional Negative Pressure Wound Therapy vs Standard Wound
   Dressing on the Development of Surgical Site Infection after Spinal
   Surgery: A Prospective Observational Study
SO NEUROSURGERY
LA English
DT Meeting Abstract
CT Conference on Neurosurgery 20/20
CY DEC, 2021
CL ELECTR NETWORK
RI Mueller, Kyle/HSI-4288-2023; D'Antuono, Matthew/AAD-5725-2020; Pivayzan,
   Gnel/JJF-1220-2023
NR 0
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-396X
EI 1524-4040
J9 NEUROSURGERY
JI Neurosurgery
PD DEC
PY 2021
VL 89
SU 2
BP S129
EP S129
PG 1
WC Clinical Neurology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Neurosciences & Neurology; Surgery
GA YY2HG
UT WOS:000754613500129
DA 2026-07-24
ER

PT J
AU Dutton, M
   Curtis, K
AF Dutton, M.
   Curtis, K.
TI Well-wound therapy: use of NPWT to prevent laparotomy breakdown
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE negative pressure wound therapy; prevention strategy; well-wound
   therapy; laparotomy breakdown
AB The use of negative pressure wound therapy (NPWT) for the treatment of wounds is not uncommon in modern health-care systems. However, use of NPWT as a wound prevention strategy, or 'well-wound therapy', is not so common. To date, papers that do discuss the use of NPWT in this way have focused mainly on orthopaedic and sternotomy wounds. This case study will present the use of NPWT with the goal of preventing laparotomy breakdown, utilising an innovative splinting technique.
C1 [Dutton, M.; Curtis, K.] St George Hosp, Trauma Serv, Sydney, NSW, Australia.
   [Dutton, M.; Curtis, K.] Univ Sydney, Sydney Nursing Sch, Sydney, NSW 2006, Australia.
   [Curtis, K.] George Inst Global Hlth, Sydney, NSW, Australia.
C3 St George Hospital; University of Sydney; George Institute for Global
   Health
RP Dutton, M (通讯作者)，St George Hosp, Trauma Serv, Sydney, NSW, Australia.
EM Matthew.Dutton@sesiahs.health.nsw.gov.au
RI ; Dutton, Matthew/PTF-9105-2026
OI Curtis, Kate/0000-0002-3746-0348; 
CR Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Doughty Dorothy B, 2004, Home Healthc Nurse, V22, P364, DOI 10.1097/00004045-200406000-00003
   Ferguson M, 1999, NUTRITION, V15, P458, DOI 10.1016/S0899-9007(99)00084-2
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   Witham Gary, 2003, Nurs Times, V99, P30
NR 10
TC 4
Z9 5
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD AUG
PY 2012
VL 21
IS 8
BP 386
EP 388
DI 10.12968/jowc.2012.21.8.386
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 990EX
UT WOS:000307614900006
PM 22885311
DA 2026-07-24
ER

PT J
AU Andrianello, S
   Landoni, L
   Bortolato, C
   Iudici, L
   Tuveri, M
   Pea, A
   De Pastena, M
   Malleo, G
   Bonamini, D
   Manzini, G
   Bassi, C
   Salvia, R
AF Andrianello, Stefano
   Landoni, Luca
   Bortolato, Cecilia
   Iudici, Livio
   Tuveri, Massimiliano
   Pea, Antonio
   De Pastena, Matteo
   Malleo, Giuseppe
   Bonamini, Deborah
   Manzini, Gessica
   Bassi, Claudio
   Salvia, Roberto
TI Negative pressure wound therapy for prevention of surgical site
   infection in patients at high risk after clean-contaminated major
   pancreatic resections: A single-center, phase 3, randomized clinical
   trial
SO SURGERY
LA English
DT Article
ID INTERNATIONAL STUDY-GROUP; COMPLICATIONS; SURGERY;
   PANCREATICODUODENECTOMY; DEFINITION; LAPAROTOMY
AB Background: Surgical site infections are an important burden of pancreatic surgery, prolonging hospitalization and delaying adjuvant treatment. The aim of this study was to compare negative pressure wound therapy with standard sterile dressing in terms of the prevention of non-organ-space surgical site infection (superficial and deep surgical site infection) in the high risk setting.
   Methods: The trial was conducted at the University of Verona Hospital Trust, Verona, Italy, from July 25, 2018, through October 10, 2019, among adults undergoing surgery for periampullary neoplasms. Only patients at high-risk for surgical site infection based on body mass index, diabetes, steroids, neoadjuvant therapy, American Society of Anesthesiologists score, Charlson comorbidity index, duration of surgery, and blood loss were included and randomized.
   Results: A total of 351 patients were screened, 100 met the inclusion criteria and were 1:1 allocated in the 2 arms. The difference in terms of non-organ-space surgical site infection comparing negative pressure wound therapy with standard sterile dressing was not significant (10.9 vs 12.2%, risk ratio [RR] 1.144, confidence interval [CI] 95% 0.324-4.040, P = 1.000). Hematomas (4.3 vs 2%, RR 1.565, CI 95% 0.312-7.848, P =.609) and organ-space infections (46.7 vs 43.8%, RR 1.059, CI 95% 0.711-1.576, P =.836) were similar. Negative pressure wound therapy prevented the development of seromas (0 vs 12.2%, RR 0.483, CI 95% 0.390-0.599, P = .027). The aesthetic result assessed on postoperative day 7 was better in the negative pressure wound therapy group (visual analogue scale, 8 vs 7, P = .029; Stony Brook Scar Evaluation Scale, 3.2 vs 2.5, P = .009), but it was no more evident on postoperative day 30 after a total number of 23 dropouts.
   Conclusion: Compared with standard sterile dressing, negative pressure wound therapy is not associated with an improved rate of non-organ-space surgical site infection after surgery for periampullary neoplasms in patients at high risk for surgical site infection. Additional studies will help identify the population that could benefit most from this intervention.
   (c) 2020 Elsevier Inc. All rights reserved.
C1 [Andrianello, Stefano; Landoni, Luca; Bortolato, Cecilia; Iudici, Livio; Tuveri, Massimiliano; Pea, Antonio; De Pastena, Matteo; Malleo, Giuseppe; Bonamini, Deborah; Manzini, Gessica; Bassi, Claudio; Salvia, Roberto] Univ Verona Hosp Trust, Dept Gen & Pancreat Surg, Pancreas Inst, Ple Scuro 10, I-37134 Verona, Italy.
C3 University of Verona; Azienda Ospedaliera Universitaria Integrata Verona
RP Bassi, C (通讯作者)，Univ Verona Hosp Trust, Dept Gen & Pancreat Surg, Pancreas Inst, Ple Scuro 10, I-37134 Verona, Italy.
EM claudio.bassi@univr.it
RI Pea, Antonio/AAC-5994-2022; De Pastena, Matteo/J-5623-2019; Malleo,
   Giuseppe/J-1773-2018; Malleo, Giuseppe/J-4395-2012; Andrianello,
   Stefano/H-9655-2019
OI Pea, Antonio/0000-0002-0509-6756; Landoni, Luca/0000-0002-2474-3496; De
   Pastena, Matteo/0000-0001-5244-4357; Malleo,
   Giuseppe/0000-0001-5467-2628; BONAMINI, Deborah/0000-0001-7439-2754;
   Malleo, Giuseppe/0000-0001-5467-2628; 
FU Associazione Italiana per la Ricerca sul Cancro (AIRC) [12182, 17132];
   Italian Ministry of Health [FIMPCUP_J33G13000210001]; FP7 European
   Community Grant Cam-Pac [602783]
FX This work was supported by Associazione Italiana per la Ricerca sul
   Cancro (AIRC n.12182 and n.17132); the Italian Ministry of Health
   (FIMPCUP_J33G13000210001); and the FP7 European Community Grant Cam-Pac
   (n. 602783). The funding agencies had no role in the collection,
   analysis, and interpretation of data or in the writing of the
   manuscript. The authors did not provide preregistration for this study.
   If requested, de-identified data collected for this randomized clinical
   trial, the study protocol, and informed consent forms will be made
   available. Please contact the institutional review board (Comitato Etico
   delle Provice di Verona e Rovigo), which will review all requests
   received. All studies carried out with these data will be supported by
   the investigators of this trial only after approval by the institutional
   review board.
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   Wente MN, 2007, SURGERY, V142, P20, DOI 10.1016/j.surg.2007.02.001
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NR 36
TC 19
Z9 22
U1 0
U2 10
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
EI 1532-7361
J9 SURGERY
JI Surgery
PD MAY
PY 2021
VL 169
IS 5
BP 1069
EP 1075
DI 10.1016/j.surg.2020.10.029
EA MAY 2021
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA RY1PQ
UT WOS:000647689600021
PM 33257037
DA 2026-07-24
ER

PT J
AU Afzal, H
   Dawson, E
   Fonseca, R
   Canas, M
   Diaz, L
   Filippis, AD
   Mazuski, J
   Bochicchio, KM
   Bochicchio, GV
AF Afzal, Hussain
   Dawson, Erin
   Fonseca, Ricardo
   Canas, Melissa
   Diaz, Leonardo
   Filippis, Alejandro De
   Mazuski, John
   Bochicchio, Kelly M.
   Bochicchio, Grant V.
TI Negative Pressure Wound Therapy With and Without Instillation in
   Necrotizing Soft Tissue Infections
SO SURGICAL INFECTIONS
LA English
DT Article
DE necrotizing soft tissue infection; negative pressure wound therapy;
   negative pressure wound therapy with instillation
ID RETROSPECTIVE ANALYSIS; MORTALITY; PREDICTORS; MANAGEMENT
AB Background: Necrotizing soft tissue infections (NSTIs) are rare but deadly infections that require early and often extensive surgical debridement. After debridement, patients frequently have substantial morbidity because of large, open wounds. Hypothesis: Negative pressure wound therapy with instillation (NPWTi) results in higher wound closure rates compared with traditional negative pressure wound therapy (NPWT) or wet to dry dressings (moist wound care dressing). Patients and Methods: A prospectively maintained Acute and Critical Care Surgery database spanning 2008-2018 was queried for patients with a diagnosis of necrotizing fasciitis, Fournier gangrene, or gas gangrene. Data were collected on patient comorbidities, operative management, and clinical outcomes. Patients were stratified by use of moist wound care dressing, traditional NPWT, or NPWTi. Data were analyzed using analysis of variance (ANOVA), chi(2), and logistic regression. Results: During the 10-year study period, patients were treated for NSTI; 173 were managed with moist wound care dressing, 150 with NPWT, and 48 with NPWTi. Patients were similar in terms of demographics, body mass index (BMI), diabetes mellitus, and smoking rates. Overall, complication rates were not substantially different, but mortality was higher in the moist wound care dressing group (16.2% vs. 10.7% NPWT vs. 2.1% NPWTi; p = 0.02). In the moist wound care dressing group, 81.5% of patients had an open wound at discharge compared with 52.7% of the NPWT group and only 14.6% of the NPWTi group (p < 0.001). On multivariable regression, NPWTi was associated with closure rates five times higher than the NPWT group (odds ratio [OR], 5.28; 95% confidence interval [CI], 2.40-11.61; p < 0.001) after controlling for smoking status, intravenous drug use, number of operations, and involvement of the most common region of the body. Conclusions: Negative pressure wound therapy with instillation is associated with higher rates of wound closure without increasing complication rates in patients with NSTI compared with traditional NPWT or moist wound care dressing. Although prospective studies are needed, this indicates the potential to improve patient quality of life through reduced pain and outpatient home health needs.
C1 [Afzal, Hussain; Fonseca, Ricardo; Canas, Melissa; Diaz, Leonardo; Mazuski, John; Bochicchio, Kelly M.; Bochicchio, Grant V.] Washington Univ, Sch Med, Acute & Crit Care Surg, 660 South Euclid Ave,Campus Box 8109, St Louis, MO 63110 USA.
   [Dawson, Erin] Penn Med, Trauma & Surg Crit Care, Philadelphia, PA USA.
   [Filippis, Alejandro De] Dartmouth Hlth, Gen Surg, Lebanon, NH USA.
C3 Washington University (WUSTL); University of Pennsylvania; Pennsylvania
   Medicine
RP Afzal, H (通讯作者)，Washington Univ, Sch Med, Acute & Crit Care Surg, 660 South Euclid Ave,Campus Box 8109, St Louis, MO 63110 USA.
EM hussain.afzal@wustl.edu
RI ; Fonseca, Ricardo/JCO-8533-2023; hizmali, lokman/AAA-8899-2021;
   Batirel, Ayse/KUC-6287-2024; zerdali, esra/AAQ-3482-2021; Yardimci,
   Ahmet Cem/AAQ-8148-2021; Singil, Sarp/JAC-2738-2023; /AAF-5652-2021;
   Rasa, Huseyin/AAG-3531-2021; GUL, OZLEM/KUF-4319-2024; Şahin,
   Ahmet/IZP-6944-2023
OI Díaz Agurto, Leonardo/0000-0002-4261-2000; Dawson,
   Erin/0000-0003-0702-4032; Fonseca, Ricardo/0000-0003-2363-1270; 
CR Anaya DA, 2007, CLIN INFECT DIS, V44, P705, DOI 10.1086/511638
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NR 20
TC 13
Z9 15
U1 0
U2 9
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD APR 1
PY 2024
VL 25
IS 3
BP 199
EP 205
DI 10.1089/sur.2023.299
EA FEB 2024
PG 7
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA A3T7Q
UT WOS:001179140700001
PM 38417035
DA 2026-07-24
ER

PT J
AU Richterich, JP
   Heigl, A
   Muff, B
   Luchsinger, S
   Gutzwiller, JP
AF Richterich, Jean-Pierre
   Heigl, Andres
   Muff, Brigitte
   Luchsinger, Sylke
   Gutzwiller, Jean-Pierre
TI Endo-SPONGE-a new endoscopic treatment option in colonoscopy
SO GASTROINTESTINAL ENDOSCOPY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; IATROGENIC PERFORATION; ANASTOMOTIC LEAKAGE;
   COLORECTAL-CANCER; WOUND CONTROL; MANAGEMENT; COMPLICATIONS;
   MULTICENTER; GUIDELINES; EXPERIENCE
C1 [Gutzwiller, Jean-Pierre] Spital Zofingen, Gastroenterol Unit, CH-4800 Zofingen, Switzerland.
   [Richterich, Jean-Pierre] Spital Zofingen, Div Surg, CH-4800 Zofingen, Switzerland.
   [Heigl, Andres; Muff, Brigitte] Spital Bulach, Dept Surg, Bulach, Switzerland.
RP Richterich, JP (通讯作者)，Spital Zofingen, Gastroenterol Unit, Muhlethalstr 27, CH-4800 Zofingen, Switzerland.
CR Anderson ML, 2000, AM J GASTROENTEROL, V95, P3418, DOI 10.1111/j.1572-0241.2000.03356.x
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NR 19
TC 5
Z9 7
U1 0
U2 0
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0016-5107
J9 GASTROINTEST ENDOSC
JI Gastrointest. Endosc.
PD NOV
PY 2008
VL 68
IS 5
BP 1019
EP 1022
DI 10.1016/j.gie.2008.02.038
PG 4
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA 368MC
UT WOS:000260624200048
PM 18534581
DA 2026-07-24
ER

PT J
AU Sapci, I
   Camargo, M
   Duraes, L
   Jia, X
   Hull, TL
   Ashburn, J
   Valente, MA
   Holubar, SD
   Delaney, CP
   Gorgun, E
   Steele, SR
   Liska, D
AF Sapci, Ipek
   Camargo, Mariane
   Duraes, Leonardo
   Jia, Xue
   Hull, Tracy L.
   Ashburn, Jean
   Valente, Michael A.
   Holubar, Stefan D.
   Delaney, Conor P.
   Gorgun, Emre
   Steele, Scott R.
   Liska, David
TI Effect of Incisional Negative Pressure Wound Therapy on Surgical Site
   Infections in High-Risk Reoperative Colorectal Surgery: A Randomized
   Controlled Trial
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article; Proceedings Paper
CT Annual Meeting of the American-Society-of-Colon-and-Rectal-Surgeons
CY APR 24-28, 2021
CL San Diego, CA
SP Amer Soc Colon & Rectal Surg
DE Negative pressure wound therapy; Reoperative colorectal surgery;
   Surgical site infection
ID CARE IMPROVEMENT PROJECT; LAPAROTOMY; PREVENTION; IMPACT
AB BACKGROUND: Colorectal resections have relatively high rates of surgical site infections causing significant morbidity. Incisional negative pressure wound therapy was introduced to improve wound healing of closed surgical incisions and to prevent surgical site infections.
   OBJECTIVE: This randomized controlled trial aimed to investigate the effect of incisional NPWT on superficial surgical site infections in high-risk, open, reoperative colorectal surgery.
   DESIGN: This was a single-center randomized controlled trial conducted between July 2015-October 2020. Patients were randomly assigned to incisional negative pressure wound therapy or standard gauze dressing with a 1:1 ratio. A total of 298 patients were included.
   SETTINGS: This study was conducted at the colorectal surgery department of a tertiary-level hospital.
   PATIENTS: This study included patients older than 18 years who underwent elective reoperative open colorectal resections. Patients were excluded who had open surgery within the past 3 months, who had active surgical site infection, and who underwent laparoscopic procedures.
   MAIN OUTCOME MEASURES: The primary outcome was superficial surgical site infection within 30 days. Secondary outcomes were deep and organ-space surgical site infections within 7 days and 30 days, postoperative complications, and length of hospital stay.
   RESULTS: A total of 149 patients were included in each arm. The mean age was 51 years, and 49.5% were women. Demographics, preoperative comorbidities, and preoperative albumin levels were comparable between the groups. Overall, most surgeries were performed for IBD, and 77% of the patients had an ostomy fashioned during the surgery. No significant difference was found between the groups in 30-day superficial surgical site infection rate (14.1% in control versus 9.4% in incisional negative pressure wound therapy; p = 0.28). Deep and organ-space surgical site infections rates at 7 and 30 days were also comparable between the groups. Postoperative length of stay and complication rates (Clavien-Dindo grade) were also comparable between the groups.
   LIMITATIONS: The patient population included in the trial consisted of a selected group of high-risk patients.
   CONCLUSIONS: Incisional negative pressure wound therapy was not associated with reduced superficial surgical site infection or overall complication rates in patients undergoing high-risk reoperative colorectal resections. See Video Abstract at http://links.lww.com/DCR/B956.
C1 [Sapci, Ipek; Camargo, Mariane; Duraes, Leonardo; Jia, Xue; Hull, Tracy L.; Ashburn, Jean; Valente, Michael A.; Holubar, Stefan D.; Delaney, Conor P.; Gorgun, Emre; Steele, Scott R.; Liska, David] Cleveland Clin, Digest Dis & Surg Inst, Dept Colorectal Surg, 9500 Euclid Ave,Desk A-30, Cleveland, OH 44106 USA.
C3 Cleveland Clinic Foundation
RP Liska, D (通讯作者)，Cleveland Clin, Digest Dis & Surg Inst, Dept Colorectal Surg, 9500 Euclid Ave,Desk A-30, Cleveland, OH 44106 USA.
RI Liska, David/L-9180-2019; de Castro Duraes, Leonardo/G-7629-2016;
   Holubar, Stefan/I-3798-2019; Camargo, Mariane/LPP-8946-2024
OI Liska, David/0000-0002-8632-6065; de Castro Duraes,
   Leonardo/0000-0002-9161-5806; 
CR Abadía P, 2021, SURG INFECT, V22, P234, DOI 10.1089/sur.2019.309
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   Bonds AM, 2013, DIS COLON RECTUM, V56, P1403, DOI 10.1097/DCR.0b013e3182a39959
   Curran T, 2019, COLORECTAL DIS, V21, P110, DOI 10.1111/codi.14350
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
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NR 30
TC 5
Z9 7
U1 1
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD FEB
PY 2023
VL 66
IS 2
BP 306
EP 313
DI 10.1097/DCR.0000000000002415
PG 8
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Gastroenterology & Hepatology; Surgery
GA L3BA4
UT WOS:001022032900026
PM 35358097
DA 2026-07-24
ER

PT J
AU Zins, JE
   Djohan, RS
AF Zins, JE
   Djohan, RS
TI Use of vacuum-assisted closure for healing of a persistent perineal
   sinus following panproctocolectomy: Report of a case - Invited
   commentary
SO DISEASES OF THE COLON & RECTUM
LA English
DT Editorial Material
ID NEGATIVE-PRESSURE; WOUNDS; MANAGEMENT; SYSTEM
CR Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
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NR 12
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD AUG
PY 2004
VL 47
IS 8
BP 1407
EP 1408
PG 2
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 852JJ
UT WOS:000223751300021
DA 2026-07-24
ER

PT J
AU Maeda, T
   Yamamoto, Y
   Tanaka, S
   Hayashi, T
AF Maeda, Taku
   Yamamoto, Yuhei
   Tanaka, Soichi
   Hayashi, Toshihiko
TI Application of Vacuum-Assisted Closure Therapy and Hyperbaric Oxygen
   Therapy for an Exposed Titanium Plate After Mandible Reconstruction
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Craniofacial wound; exposed mandibular plate; hyperbaric oxygen therapy;
   vacuum-assisted closure
ID BONE MORPHOGENETIC PROTEIN-2; CLINICAL-EXPERIENCE; FREE-FLAP; DEFECTS;
   WOUNDS; HEAD
AB The authors report a case of an 84-year-old woman with an exposed mandibular plate after reconstruction, which finally healed with combination therapy using vacuum-assisted closure therapy and hyperbaric oxygen therapy. The woman was diagnosed with mucosal carcinoma of the right oral cavity. During reconstruction after segmental excision of the mandible, a titanium plate was selected based on several risk factors. After the operation, the plate became exposed at the center of the chin. A second surgery was deemed inappropriate because of her age, malnutrition, and recurrent aspiration pneumonia. Instead, combination therapy consisting of vacuum-assisted closure therapy and hyperbaric oxygen therapy was initiated, leading to epithelizaion of the wound. Adapt Barrier Rings was effectively used to generate a stable negative pressure at the complicated craniofacial wound. A surgical or conservative approach is chosen as salvage treatment of an exposed plate. In this patient, only conservative treatment involving combination therapy resulted in complete healing of the wound with plate exposure. This patient highlights 2 important clinical issues: combination therapy was effective for an exposed mandibular plate, and a dressing technique using Adapt Barrier Rings enabled stable negative pressure in the craniofacial wound.
C1 [Maeda, Taku; Yamamoto, Yuhei; Hayashi, Toshihiko] Hokkaido Univ, Grad Sch Med, Dept Plast & Reconstruct Surg, Sapporo, Hokkaido, Japan.
   [Tanaka, Soichi] Hokkaido Univ, Grad Sch Dent Med, Div Oral Pathobiol, Dept Oral & Maxillofacial Surg, Sapporo, Hokkaido, Japan.
C3 Hokkaido University; Hokkaido University
RP Hayashi, T (通讯作者)，107 Nishi 7 Chome,Kita 15 Jo,Kita Ku, Sapporo, Hokkaido, Japan.
EM toshi-116@nifty.com
RI Hayashi, Toshihiko/AAU-9776-2020
OI Hayashi, Toshihiko/0000-0002-1180-1685; MAEDA, TAKU/0000-0003-3612-8201
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   Thom SR, 2011, PLAST RECONSTR SURG, V127, p131S, DOI 10.1097/PRS.0b013e3181fbe2bf
   Wei FC, 2003, PLAST RECONSTR SURG, V112, P37, DOI 10.1097/01.PRS.0000065911.00623.BD
   Yang YH, 2013, J PLAST RECONSTR AES, V66, pE209, DOI 10.1016/j.bjps.2013.03.006
NR 13
TC 4
Z9 4
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD OCT
PY 2016
VL 27
IS 7
BP E601
EP E604
DI 10.1097/SCS.0000000000002917
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EA1KW
UT WOS:000386352100006
PM 27464555
DA 2026-07-24
ER

PT J
AU Janis, JE
   Attinger, CE
AF Janis, Jeffrey E.
   Attinger, Christopher E.
TI The clinical efficacy and cost effectiveness of the vacuum-assisted
   closure technique in the management of acute and chronic wounds: A
   randomized controlled trial - Discussion
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Editorial Material
C1 Univ Texas, SW Med Ctr Dallas, Dallas, TX 75390 USA.
C3 University of Texas System; University of Texas Southwestern Medical
   Center; University of Texas Dallas
RP Janis, JE (通讯作者)，Univ Texas, SW Med Ctr Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 USA.
EM jeffrey.janis@utsouthwestern.edu
RI Janis, Jeffrey/W-6760-2019
OI Janis, Jeffrey/0000-0001-6103-4798
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong DG, 1998, DIABETES CARE, V21, P855, DOI 10.2337/diacare.21.5.855
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   ATTINGER CF, IN PRESS PLAST RECON
   Bucalo Brian, 1993, Wound Repair and Regeneration, V1, P181, DOI 10.1046/j.1524-475X.1993.10308.x
   HEGGERS J P, 1991, Journal of Burn Care and Rehabilitation, V12, P420, DOI 10.1097/00004630-199109000-00005
   KJOLSETH D, 1994, J AM COLL SURGEONS, V179, P305
   LINEAWEAVER W, 1985, PLAST RECONSTR SURG, V75, P394, DOI 10.1097/00006534-198503000-00016
   LINEAWEAVER W, 1985, ARCH SURG-CHICAGO, V120, P267
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   NASUTION AF, 1981, BRIT J SURG, V68, P306, DOI 10.1002/bjs.1800680505
NR 11
TC 0
Z9 0
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD AUG
PY 2006
VL 118
IS 2
BP 398
EP 400
DI 10.1097/01.prs.0000227613.45038.26
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 072LM
UT WOS:000239674900019
DA 2026-07-24
ER

PT J
AU Al-Zahid, S
   Izadi, D
   Day, CJ
   Wilson, A
   Stone, C
   Smith, J
AF Al-Zahid, S.
   Izadi, D.
   Day, C. J.
   Wilson, A.
   Stone, C.
   Smith, J.
TI A novel airway management strategy for cervical necrotising fasciitis
   secondary to Bezold's abscess
SO ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND
LA English
DT Article
DE Necrotising fasciitis; Mastoiditis; Tracheotomy; Permacol (TM); Negative
   pressure wound therapy
AB We describe a rare case of cervical necrotising fasciitis caused by mastoiditis and Bezold's abscess. This case was complicated by a tracheostomy delaying wound healing. A novel strategy to repair the tracheotomy defect using Permacol (TM), an acellular porcine dermal substitute, and a local muscle flap not previously reported in the literature is described to allow the use of negative pressure wound therapy dressing. This technique may be employed in similar applications for non-healing tracheotomy wounds.
C1 [Al-Zahid, S.; Izadi, D.; Day, C. J.; Wilson, A.; Stone, C.; Smith, J.] Royal Devon & Exeter NHS Fdn Trust, Exeter, Devon, England.
C3 University of Exeter
RP Al-Zahid, S (通讯作者)，Royal Devon & Exeter NHS Fdn Trust, Exeter, Devon, England.
EM saif.alzahid@gmail.com
CR Chen SJ, 2015, BRIT J ORAL MAX SURG, V53, P642, DOI 10.1016/j.bjoms.2015.04.017
   Krenk L, 2007, EUR ARCH OTO-RHINO-L, V264, P917, DOI 10.1007/s00405-007-0275-3
NR 2
TC 4
Z9 6
U1 0
U2 2
PU ROYAL COLL SURGEONS ENGLAND
PI LONDON
PA 35-43 LINCOLN'S INN FIELDS, LONDON WC2A 3PN, ENGLAND
SN 0035-8843
EI 1478-7083
J9 ANN ROY COLL SURG
JI Ann. R. Coll. Surg. Engl.
PD JAN
PY 2019
VL 101
IS 1
BP E23
EP E25
DI 10.1308/rcsann.2018.0181
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HF3KL
UT WOS:000454133800008
PM 30322284
OA Bronze
DA 2026-07-24
ER

PT J
AU Gilbert, A
   Flynn, J
AF Gilbert, Angela
   Flynn, Joan
TI SUCCESSFUL COMBINATION OF NEGATIVE PRESSURE WOUND THERAPY (NPWT) AND A
   FISTULA/WOUND MANAGER TO CONTAIN AND PROMOTE HEALING OF WOUNDS WITH
   NONPOUCHABLE HIGH OUTPUT EC FISTULAS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Gilbert, Angela] Texas NeuroRehab, Austin, TX USA.
   [Flynn, Joan] Smith & Nephew, Austin, TX USA.
C3 Smith & Nephew
EM albgilbert@hotmail.com; joan.flynn@smith-nephew.com
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2011
VL 38
IS 3
SU S
MA 5205
BP S32
EP S32
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 772LI
UT WOS:000291235000085
DA 2026-07-24
ER

PT J
AU Altintas, B
   Biber, R
   Brem, MH
AF Altintas, Burak
   Biber, Roland
   Brem, Matthias H.
TI The accelerating effect of negative pressure wound therapy with Prevena™
   on the healing of a closed wound with persistent serous secretion
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Closed wound; NPWT; Wound secretion
AB Negative pressure wound therapy has been lately used on closed incisions in the immediate postoperative period to accelerate wound healing. However, there are no data in the literature regarding the use of this type of therapy for wounds with persistent secretion in the early postoperative care. We present the first report of persistent postoperative serous wound secretion in a patient after femoral nailing treated successfully with Prevena (KCI), a closed incision negative pressure management system (CINPWT).
C1 [Altintas, Burak; Biber, Roland; Brem, Matthias H.] Klinikum Nurnberg, Dept Trauma & Orthoped Surg, Nurnberg, Germany.
C3 Klinikum Nurnberg
RP Brem, MH (通讯作者)，Klinikum Nurnberg, Dept Trauma & Orthoped Surg, Breslauerstr 201, Nurnberg, Germany.
EM Matthias.brem@klinikum-nuernberg.de
RI Biber, Roland/AAP-6691-2021
OI Biber, Roland/0000-0002-7700-0311
CR DeCarbo WT, 2010, J FOOT ANKLE SURG, V49, P299, DOI 10.1053/j.jfas.2010.01.002
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Meeker J, 2011, J ORTHOP TRAUMA, V25, P756, DOI 10.1097/BOT.0b013e318211363a
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
NR 5
TC 12
Z9 13
U1 0
U2 10
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2015
VL 12
IS 6
BP 662
EP 663
DI 10.1111/iwj.12198
PG 2
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CW0VP
UT WOS:000364708200009
PM 24393137
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Lu, F
   Ogawa, R
   Nguyen, DT
   Chen, B
   Guo, DF
   Helm, DL
   Zhan, QA
   Murphy, GF
   Orgill, DP
AF Lu, Feng
   Ogawa, Rei
   Nguyen, Dinh T.
   Chen, Bin
   Guo, Danfeng
   Helm, Douglas L.
   Zhan, Qian
   Murphy, George F.
   Orgill, Dennis P.
TI Microdeformation of Three-Dimensional Cultured Fibroblasts Induces Gene
   Expression and Morphological Changes
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE vacuum-assisted closure (VAC); mechanotransduction; microdeformations;
   wound healing; fibroblast; collagen; smooth muscle actin; fibroblast
   growth factor; transforming growth factor; myofibroblast
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; PATHWAY
AB Background: Vacuum-assisted closure induces microdeformations of the wound surface and accelerates healing of complex wounds; however, a thorough understanding of the biology of cellular mechanotransduction is lacking. We hypothesized that fibroblast shape and function can be altered in an in vitro vacuum-assisted closure device.
   Methods: A 3-dimensional fibrin matrix with cultured murine fibroblasts and an intervening polyurethane foam was exposed to 125 mm Hg suction and compared with similar wells without suction. We measured fibroblast proliferation and morphology using fluorescence microscopy and gene expression change using real-time reverse-transcriptase polymerase chain reaction at 24, 48, and 72 hours.
   Results: Wells exposed to suction induced significant proliferation of fibroblasts and morphologic changes visible by larger, rounder, and notable dendrite-like branching and process extensions. Type 1 collagen alpha 1 (COL1A1), fibroblast growth factor 2 (FGF2, bFGF), and transforming growth factor beta 1 (TGF beta 1) were all up-regulated after 48 hours of exposure to suction. Smooth muscle actin alpha 2 (Acta2, alpha-SMA) was up-regulated after 72 hours.
   Conclusions: Microdeformations produced by the combination of polyurethane foam and suction are associated with increased fibroblast proliferation and up-regulation of gene expressions in fibroblasts.
C1 [Lu, Feng; Ogawa, Rei; Nguyen, Dinh T.; Chen, Bin; Guo, Danfeng; Helm, Douglas L.; Orgill, Dennis P.] Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, Boston, MA 02115 USA.
   [Lu, Feng] So Med Univ, Dept Plast & Reconstruct Surg, Nanfang Hosp, Guangzhou, Guangdong, Peoples R China.
   [Ogawa, Rei] Nippon Med Sch, Dept Plast Reconstruct & Aesthet Surg, Tokyo 113, Japan.
   [Chen, Bin] Kunming Med Coll, Affiliated Hosp 2, Dept Burn & Plast Surg, Kunming, Peoples R China.
   [Guo, Danfeng] Cent Hosp Jian, Dept Plast Surg, Jian, Shandong, Peoples R China.
   [Zhan, Qian; Murphy, George F.] Harvard Univ, Sch Med, Brigham & Womens Hosp, Program Dermatopathol,Dept Pathol, Boston, MA 02115 USA.
C3 Harvard University; Harvard Medical School; Harvard University Medical
   Affiliates; Brigham & Women's Hospital; Southern Medical University -
   China; Nippon Medical School; Kunming Medical University; Harvard
   University; Harvard Medical School; Harvard University Medical
   Affiliates; Brigham & Women's Hospital
RP Orgill, DP (通讯作者)，Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
EM dorgill@partners.org
RI /AAG-3449-2019; Orgill, Dennis/H-7596-2019
OI Chen, Bin/0000-0002-7606-1382; Orgill, Dennis/0000-0002-8279-7310
FU KCI
FX Dennis P. Orgill, MD, PhD, is the principal investigator on research
   grants to Brigham and Women's Hospital by KCI, and is an expert witness
   for KCI, San Antonio, Texas. The bioreactor used in this study, suction
   apparatus, and foam were provided by KCI.
CR Abe R, 2001, J IMMUNOL, V166, P7556, DOI 10.4049/jimmunol.166.12.7556
   Angele P, 2003, J ORTHOPAED RES, V21, P451, DOI 10.1016/S0736-0266(02)00230-9
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Branski LK, 2009, BURNS, V35, P171, DOI 10.1016/j.burns.2008.03.009
   Chin MS, 2009, PLAST RECONSTR SURG, V124, P102, DOI 10.1097/PRS.0b013e3181a81542
   Danciu TE, 2003, FEBS LETT, V536, P193, DOI 10.1016/S0014-5793(03)00055-3
   Elder SH, 2008, BIORHEOLOGY, V45, P479, DOI 10.3233/BIR-2008-0496
   Gurtner GC, 2008, NATURE, V453, P314, DOI 10.1038/nature07039
   Hinz B, 2001, MOL BIOL CELL, V12, P2730, DOI 10.1091/mbc.12.9.2730
   Kim H, 2008, BIOCHEM BIOPH RES CO, V377, P636, DOI 10.1016/j.bbrc.2008.10.030
   Kim K, 2002, EXP CELL RES, V275, P171, DOI 10.1006/excr.2002.5503
   MCNULTY A, 2007, WOUND REPAIR REGEN, V15, pA41
   McNulty AK, 2009, WOUND REPAIR REGEN, V17, P192, DOI 10.1111/j.1524-475X.2009.00460.x
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   SPURGER L, 2002, ENDOPLASMIC RETICULU
   Thampatty Bhavani P., 2008, V1, P351, DOI 10.1007/978-1-4020-6426-5_16
   Wang Z, 2006, J CELL PHYSIOL, V206, P510, DOI 10.1002/jcp.20486
   Wilkes RP, 2007, TISSUE ENG, V13, P3003, DOI 10.1089/ten.2007.0036
NR 21
TC 70
Z9 83
U1 0
U2 16
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD MAR
PY 2011
VL 66
IS 3
BP 296
EP 300
DI 10.1097/SAP.0b013e3181ea1e9b
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 719UX
UT WOS:000287237800017
PM 21233699
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Passera, E
   Guanella, G
   Meroni, A
   Chiesa, G
   Rizzi, A
   Rocco, G
AF Passera, Eliseo
   Guanella, Giovanni
   Meroni, Alberto
   Chiesa, Giuseppe
   Rizzi, Adriano
   Rocco, Gaetano
TI Amplatzer Device and Vacuum-Assisted Closure Therapy to Treat a Thoracic
   Empyema With Bronchopleural Fistula
SO ANNALS OF THORACIC SURGERY
LA English
DT Editorial Material
ID OPEN WINDOW THORACOSTOMY; POSTPNEUMONECTOMY EMPYEMA; ENDOBRONCHIAL
   CLOSURE; MANAGEMENT
AB We present a case of lower bilobectomy complicated by a large bronchopleural fistula and empyema 1 month after primary surgery. The patient was immediately treated with an open window thoracostomy. After surgical debridement, an Amplatzer Septal Occluder device (AGA Medical Corp, Plymouth, MN) was positioned to close the fistula. Thereafter, the thoracostomy rapidly and spontaneously closed with vacuum-assisted closure therapy. (Ann Thorac Surg 2011;92:e23-5) (C) 2011 by The Society of Thoracic Surgeons
C1 Humanitas Gavazzeni Hosp, Dept Thorac Surg, Bergamo, Italy.
   Natl Canc Inst, Div Thorac Surg, Dept Thorac Surg & Oncol, Naples, Italy.
C3 Istituto Clinico Humanitas Gavazzeni; IRCCS Fondazione Pascale
RP Passera, E (通讯作者)，Via Quintino Basso 13-B, I-24123 Bergamo, Italy.
EM eliseo.passera@gavazzeni.it
RI Rocco, Gaetano/K-4801-2016
OI Rocco, Gaetano/0000-0003-4150-8604
CR Aru GM, 2010, ANN THORAC SURG, V90, P266, DOI 10.1016/j.athoracsur.2010.04.092
   CLAGETT OT, 1963, J THORAC CARDIOV SUR, V45, P141, DOI 10.1016/S0022-5223(19)32877-6
   Kramer MR, 2008, CHEST, V133, P1481, DOI 10.1378/chest.07-1961
   Lois M, 2005, CHEST, V128, P3955, DOI 10.1378/chest.128.6.3955
   Massera F, 2006, ANN THORAC SURG, V82, P288, DOI 10.1016/j.athoracsur.2005.11.046
   Masura J, 2005, J AM COLL CARDIOL, V45, P505, DOI 10.1016/j.jacc.2004.10.066
   Palmen M, 2009, ANN THORAC SURG, V88, P1131, DOI 10.1016/j.athoracsur.2009.06.030
   Tedde ML, 2009, ANN THORAC SURG, V88, pE25, DOI 10.1016/j.athoracsur.2009.06.069
NR 8
TC 12
Z9 21
U1 0
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD AUG
PY 2011
VL 92
IS 2
BP E23
EP E25
DI 10.1016/j.athoracsur.2011.03.047
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 798OX
UT WOS:000293221000002
PM 21801895
DA 2026-07-24
ER

PT J
AU Rajabaleyan, P
   Vang, A
   Möller, S
   Khalaf, S
   Ladegaard, AG
   Qvist, N
   Ellebæk, MB
AF Rajabaleyan, Pooya
   Vang, Ask
   Moller, Soeren
   Khalaf, Sardar
   Ladegaard, Anna Gosvig
   Qvist, Niels
   Ellebaek, Mark Bremholm
TI Author's Reply: Vacuum-Assisted Closure Significantly Reduces Surgical
   Postoperative Complications Compared With Primary Abdominal Closure in
   Patients With Secondary Peritonitis: A Comparative Retrospective Study
SO WORLD JOURNAL OF SURGERY
LA English
DT Letter
C1 [Rajabaleyan, Pooya; Vang, Ask; Khalaf, Sardar; Ladegaard, Anna Gosvig; Qvist, Niels; Ellebaek, Mark Bremholm] Odense Univ Hosp, Res Unit Surg, Odense, Denmark.
   [Moller, Soeren] Odense Univ Hosp, Open Patient Data Explorat Network OPEN, Odense, Denmark.
   [Moller, Soeren] Univ Southern Denmark, Dept Clin Res, Odense, Denmark.
C3 University of Southern Denmark; Odense University Hospital; University
   of Southern Denmark; Odense University Hospital; University of Southern
   Denmark
RP Rajabaleyan, P (通讯作者)，Odense Univ Hosp, Res Unit Surg, Odense, Denmark.
EM Pooya.rajabaleyan@skane.se
RI Möller, Sören/X-8738-2019; Ellebaek, Mark Bremholm/ADW-1803-2022
OI Möller, Sören/0000-0003-0858-4269; , Sardar Khalaf/0009-0008-4358-4663;
   Rajabaleyan, Pooya/0000-0002-6882-9427; Ellebaek, Mark
   Bremholm/0000-0001-6550-7505
CR Rajabaleyan P, 2025, WORLD J SURG, V49, P387, DOI 10.1002/wjs.12472
NR 1
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD APR
PY 2025
VL 49
IS 4
BP 1137
EP 1138
DI 10.1002/wjs.12518
EA FEB 2025
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 1IV5A
UT WOS:001428062200001
PM 39984293
OA Bronze
DA 2026-07-24
ER

PT J
AU Agosti, JK
   Sharks, N
AF Agosti, Jennifer K.
   Sharks, Nurse
TI A study of combined interventions: Negative pressure wound therapy and a
   100% sodium carboxymethylcellulose fiber dressing with ionic silver for
   the management of a surgical flap
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 Nurse Sharks Inc, Weedville, PA USA.
   Nursing Consulting Serv, Weedville, PA USA.
EM nursesharks1@windstream.net
NR 0
TC 1
Z9 1
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2007
VL 34
IS 3
SU S
BP S67
EP S68
DI 10.1097/01.WON.0000271037.07681.84
PG 2
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 171ZK
UT WOS:000246773700186
DA 2026-07-24
ER

PT J
AU Schmidt, I
   Andersen, HF
   Zinther, N
AF Schmidt, Irene
   Andersen, Hans Friis
   Zinther, Nellie
TI BOTULINUM TOXIN A IN CONJUNCTION WITH NEGATIVE PRESSURE WOUND THERAPY
   AND MESH-MEDIATED FASCIAL TRACTION PROVIDES HIGH RATE OF FASCIAL CLOSURE
   IN PATIENTS WITH OPEN ABDOMEN
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
CT 8th Joint Congress of the European-Hernia-Society (EHS) and
   Americas-Hernia-Society
CY OCT 13-16, 2021
CL Copenhagen, DENMARK
SP European Hernia Soc, Americas Hernia Soc
C1 [Schmidt, Irene; Zinther, Nellie] Horsens Reg Hosp, Surg Dept, Horsens, Denmark.
   [Andersen, Hans Friis] Horsens Reg Hosp, Horsens, Denmark.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD NOV
PY 2021
VL 108
SU 8
MA P128
AR znab395.121
DI 10.1093/bjs/znab395.121
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA XT1NC
UT WOS:000733361300121
OA Bronze
DA 2026-07-24
ER

PT J
AU Schellenberg, M
   Chong, V
   Cone, J
   Keeley, J
   Inaba, K
AF Schellenberg, Morgan
   Chong, Vincent
   Cone, Jennifer
   Keeley, Jessica
   Inaba, Kenji
TI Extremity compartment syndrome
SO CURRENT PROBLEMS IN SURGERY
LA English
DT Review
ID NEAR-INFRARED SPECTROSCOPY; ACUTE KIDNEY INJURY; VACUUM-ASSISTED
   CLOSURE; SERUM CREATINE-KINASE; LOWER LEG; LITHOTOMY POSITION; TISSUE
   PRESSURE; RENAL-FAILURE; FASCIOTOMY; TRAUMA
C1 [Schellenberg, Morgan; Chong, Vincent; Keeley, Jessica] Trauma & Surg Crit Care LAC USC Med Ctr, Los Angeles, CA USA.
   [Cone, Jennifer] Univ Chicago, Med Ctr, Div Trauma & Acute Care Surg, Surg, Chicago, IL 60637 USA.
   [Inaba, Kenji] Univ Southern Calif, Surg, Emergency Med, Los Angeles, CA USA.
   [Inaba, Kenji] Univ Southern Calif, Surg Intens Care Unit, Los Angeles, CA USA.
   [Inaba, Kenji] Univ Southern Calif, Los Angeles, CA USA.
C3 University of Chicago; University of Chicago Medical Center; University
   of Southern California; University of Southern California; University of
   Southern California
RP Inaba, K (通讯作者)，Univ Southern Calif, LAC USC Med Ctr, Div Trauma & Surg Crit Care, 2051 Marengo St,Inpatient Tower,C5L100, Los Angeles, CA 90033 USA.
EM kinaba@surgery.usc.edu
RI Inaba, Kenji/AAC-8532-2020
OI Inaba, Kenji/0000-0002-5191-596X
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NR 75
TC 3
Z9 3
U1 0
U2 4
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0011-3840
EI 1535-6337
J9 CURR PROB SURG
JI Curr. Probl. Surg.
PD JUL
PY 2018
VL 55
IS 7
BP 256
EP 273
DI 10.1067/j.cpsurg.2018.08.002
PG 18
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HE0FM
UT WOS:000452942200002
PM 30470346
DA 2026-07-24
ER

PT J
AU Chang, CC
   Tang, WR
   Huang, WL
   Chen, YY
   Yen, YT
   Tseng, YL
AF Chang, Chao-Chun
   Tang, Wen-Ruei
   Huang, Wei-Li
   Chen, Ying-Yuan
   Yen, Yi-Ting
   Tseng, Yau-Lin
TI ASO Visual Abstract: Algorithmic Approach with Negative Pressure Wound
   Therapy Improved Survival in Patients with Synchronous Hypopharyngeal
   and Esophageal Cancer Undergoing Pharyngolaryngoesophagectomy with
   Gastric Tube Reconstruction
SO ANNALS OF SURGICAL ONCOLOGY
LA English
DT Editorial Material
C1 [Chang, Chao-Chun; Tang, Wen-Ruei; Huang, Wei-Li; Chen, Ying-Yuan; Yen, Yi-Ting; Tseng, Yau-Lin] Natl Cheng Kung Univ Hosp, Div Thorac Surg, Dept Surg, Tainan, Taiwan.
   [Chang, Chao-Chun; Yen, Yi-Ting] Natl Cheng Kung Univ Hosp, Div Trauma & Acute Care Surg, Dept Surg, Tainan, Taiwan.
C3 National Cheng Kung University; National Cheng Kung University Hospital;
   National Cheng Kung University; National Cheng Kung University Hospital
RP Yen, YT (通讯作者)，Natl Cheng Kung Univ Hosp, Div Thorac Surg, Dept Surg, Tainan, Taiwan.; Yen, YT (通讯作者)，Natl Cheng Kung Univ Hosp, Div Trauma & Acute Care Surg, Dept Surg, Tainan, Taiwan.
EM b85401067@gmail.com
RI Yen, Yi-Ting/AAQ-1691-2020
NR 0
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1068-9265
EI 1534-4681
J9 ANN SURG ONCOL
JI Ann. Surg. Oncol.
PD DEC
PY 2021
VL 28
IS SUPPL 3
SU 3
BP 769
EP 770
DI 10.1245/s10434-021-10471-7
EA OCT 2021
PG 2
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA XD7PH
UT WOS:000707525700004
PM 34652565
DA 2026-07-24
ER

PT J
AU Alcantara, S
   Goss, S
   Schwartz, J
   Gendics, C
   Lantis, J
AF Alcantara, Sean
   Goss, Selena
   Schwartz, Jamie
   Gendics, Cynthia
   Lantis, John
TI Cost Analysis of Negative Pressure Wound Therapy with Instillation for
   Wound Bed Preparation Preceding Split-Thickness Skin Grafts for Massive
   (&gt;100 cm2) Chronic Venous Leg Ulcers
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Meeting Abstract
CT Vascular Annual Meeting of the Society-for-Vascular-Surgery
CY JUN 05-07, 2014
CL Boston, MA
SP Soc Vasc Surg
C1 [Alcantara, Sean; Goss, Selena; Schwartz, Jamie; Gendics, Cynthia; Lantis, John] St Lukes Roosevelt Hosp, New York, NY 10025 USA.
C3 Mount Sinai Morningside; Mount Sinai West
NR 0
TC 0
Z9 0
U1 0
U2 3
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
J9 J VASC SURG
JI J. Vasc. Surg.
PD JUN
PY 2014
VL 59
IS 6
SU S
BP 77S
EP 78S
DI 10.1016/j.jvs.2014.03.173
PG 2
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery; Cardiovascular System & Cardiology
GA AI9ND
UT WOS:000337258400160
OA Bronze
DA 2026-07-24
ER

PT J
AU Tahir, M
   Chaudhry, EA
   Zimri, FK
   Ahmed, N
   Shaikh, SA
   Khan, S
   Choudry, UK
   Aziz, A
   Jamali, AR
AF Tahir, M.
   Chaudhry, E. A.
   Zimri, F. K.
   Ahmed, N.
   Shaikh, S. A.
   Khan, S.
   Choudry, U. K.
   Aziz, A.
   Jamali, A. R.
TI 撤稿声明: Negative pressure wound therapy versus conventional dressing for
   open fractures in lower extremity trauma: a multicentre randomized
   controlled trial (Retraction of Vol 103, Pg 912, 2020)
SO BONE & JOINT JOURNAL
LA English
DT Retraction
CR Costa ML, 2018, JAMA-J AM MED ASSOC, V319, P2280, DOI 10.1001/jama.2018.6452
NR 1
TC 0
Z9 0
U1 0
U2 1
PU BRITISH EDITORIAL SOC BONE & JOINT SURGERY
PI LONDON
PA 22 BUCKINGHAM STREET, LONDON WC2N 6ET, ENGLAND
SN 2049-4394
J9 BONE JOINT J
JI Bone Joint J.
PD SEP
PY 2021
VL 103B
IS 9
BP 1550
EP 1550
PG 1
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA WC7KE
UT WOS:000704432100016
DA 2026-07-24
ER

PT J
AU Agarwal, P
   Sharma, D
AF Agarwal, Pawan
   Sharma, D.
TI Correspondence: Comment on 'Randomized clinical trial of negative
   pressure wound therapy as an adjunctive treatment for small-area thermal
   burns in children' by Frear et al.
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Letter
C1 [Agarwal, Pawan; Sharma, D.] NSCB Govt Med Coll, Dept Surg, Jabalpur, India.
RP Agarwal, P (通讯作者)，292-293 Napier Town, Jabalpur 482003, MP, India.
EM drpawanagarwal@yahoo.com
RI ; Agarwal, Pawan/E-1885-2011
OI Sharma, Dhananjaya/0000-0002-0604-8676; Agarwal,
   Pawan/0000-0002-9031-8690
CR Frear CC, 2020, BJS-BRIT J SURG, V107, P1741, DOI 10.1002/bjs.11993
NR 1
TC 0
Z9 0
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD FEB
PY 2021
VL 108
IS 2
BP E86
EP E86
DI 10.1093/bjs/znaa077
EA JAN 2021
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA RI6NP
UT WOS:000637024200017
PM 33711130
OA Bronze
DA 2026-07-24
ER

PT J
AU Johnson, R
   Arnold-Long, M
AF Johnson, Richard, Sr.
   Arnold-Long, Mary
TI CASE STUDY: THE USE OF A COLLAGEN ALGINATE-To ACCELERATE THE HEALING
   PROCESS OF UNDERMINED AND TUNNELED TISSUE IN CONJUNCTION WITH NEGATIVE
   PRESSURE WOUND THERAPY (NPWT)
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Johnson, Richard, Sr.; Arnold-Long, Mary] Drake Ctr, Cincinnati, OH USA.
EM mary.long@healthall.com; mary.long@healthall.com
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2009
VL 36
IS 3
SU S
BP S16
EP S16
DI 10.1097/01.WON.0000351927.76576.6f
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 446KH
UT WOS:000266120000042
DA 2026-07-24
ER

PT J
AU Hill, R
AF Hill, Rosemary
TI THE POSITIVE OUTCOMES ASSOCIATED WITH THE USE OF INCISIONAL NEGATIVE
   PRESSURE WOUND THERAPY WITH 6 PATIENTS WHO WERE CONSIDERED HIGH-RISK FOR
   WOUND COMPLICATIONS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
ID PREVENTION; INFECTION
C1 [Hill, Rosemary] Ambulatory Program, N Vancouver, BC, Canada.
EM rosemary.hill@vch.ca
CR Blackham AU, 2013, AM J SURG, V205, P647, DOI 10.1016/j.amjsurg.2012.06.007
   Bonds AM, 2013, DIS COLON RECTUM, V56, P1403, DOI 10.1097/DCR.0b013e3182a39959
   Vargo D, 2012, AM J SURG, V204, P1021, DOI 10.1016/j.amjsurg.2012.10.004
NR 3
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2017
VL 44
IS 3
SU S
MA CS32
BP S19
EP S19
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA EV4HE
UT WOS:000401718800045
DA 2026-07-24
ER

PT J
AU Gamblin, TC
   D'Angelica, M
   Bender, J
   Stanley, JD
   Shen, P
AF Gamblin, T. Clark
   D'Angelica, Michael
   Bender, Jeffrey
   Stanley, J. Dan
   Shen, Perry
TI Phase II Randomized Trial of Negative-Pressure Wound Therapy to Decrease
   Surgical Site Infection in Patients Undergoing Laparotomy for
   Gastrointestinal, Pancreatic, and Peritoneal Surface Malignancies
   Discussion
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Editorial Material
NR 0
TC 0
Z9 0
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD APR
PY 2017
VL 224
IS 4
BP 737
EP 739
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EW4SR
UT WOS:000402491700067
DA 2026-07-24
ER

PT J
AU Chicco, M
   Ahmadi, AR
   Lin, FY
   Cheng, HT
   Lee, MM
AF Chicco, Maria
   Ahmadi, Ali R.
   Lin, Fu-Yu
   Cheng, Hsu-Tang
   Lee, Min-Min
TI Combination of Autologous Fat Grafting and Negative-Pressure Wound
   Therapy for the Treatment of Scalp Linear Scleroderma
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Craniofacial reconstruction; fat grafting; negative-pressure wound
   therapy; scalp linear scleroderma
ID TERM
AB Scalp linear scleroderma (LSc) is a subtype of localized scleroderma which typically affects young patients and which can be severely disfiguring. Traditional treatment options include bone grafting or tissue expansion. in this report, we present the case of a patient with scalp LSc successfully treated with scar release, autologous fat grafting, and negative-pressure wound therapy (NPWT). A 55-year-old female, with a history of craniectomy for a benign sellar tumor 10 years previously, developed LSc over the frontal scalp with exposure of titanium plates and screws. She was treated with removal of metalwork, scar release, autologous fat grafting from the abdominal wall and immediate application of NPWT. At 3-month postoperative follow-up, the appearance of the depressed lesion and of its margins had significantly improved. Our experience suggests that the combination of autologous fat grafting and NPWT is an effective treatment modality for scalp LSc.
C1 [Chicco, Maria] Oxford Univ Hosp NHS Fdn Trust, Dept Surg, John Radcliffe Hosp, Oxford, England.
   [Ahmadi, Ali R.] Erasmus MC, Dept Plast & Reconstruct Surg, Rotterdam, Netherlands.
   [Lin, Fu-Yu] China Med Univ, Dept Neurol, China Med Univ Hosp, Sch Med, Taichung, Taiwan.
   [Cheng, Hsu-Tang] Asia Univ, Coll Med & Hlth Sci, Div Plast & Reconstruct Surg, Dept Surg,Asia Univ Hosp, 222 Fuxin Rd, Taichung 41354, Taiwan.
   [Cheng, Hsu-Tang] China Med Univ Hosp, Big Data Ctr, Taichung, Taiwan.
   [Cheng, Hsu-Tang; Lee, Min-Min] Asia Univ, Dept Food Nutr & Hlth Biotechnol, Taichung, Taiwan.
C3 University of Oxford; Oxford University Hospitals NHS Foundation Trust;
   Erasmus University Rotterdam; Erasmus MC; China Medical University
   Taiwan; China Medical University Hospital - Taiwan; Asia University
   Taiwan; China Medical University Taiwan; China Medical University
   Hospital - Taiwan; Asia University Taiwan
RP Cheng, HT (通讯作者)，Asia Univ, Coll Med & Hlth Sci, Div Plast & Reconstruct Surg, Dept Surg,Asia Univ Hosp, 222 Fuxin Rd, Taichung 41354, Taiwan.
EM hsutangcheng@gmail.com
FU Asia University Hospital Research Program [AUH-10951018]
FX This study is supported in part by Asia University Hospital Research
   Program (AUH-10951018).
CR Careta MF, 2015, AN BRAS DERMATOL, V90, P62, DOI 10.1590/abd1806-4841.20152890
   Hwang Dong Yeon, 2009, J Plast Reconstr Aesthet Surg, V62, pe25, DOI 10.1016/j.bjps.2007.12.019
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   Lee SS, 2017, J CRANIOFAC SURG, V28, P629, DOI 10.1097/SCS.0000000000003410
   Thareja SK, 2015, INT J DERMATOL, V54, P823, DOI 10.1111/ijd.12108
   Zuk PA, 2002, MOL BIOL CELL, V13, P4279, DOI 10.1091/mbc.E02-02-0105
NR 7
TC 1
Z9 1
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD JUL-AUG
PY 2022
VL 33
IS 5
BP E459
EP E461
DI 10.1097/SCS.0000000000008355
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 2U5AT
UT WOS:000823174200007
PM 34759251
DA 2026-07-24
ER

PT J
AU Matthews, MR
   Fernandez, LG
AF Matthews, Marc R.
   Fernandez, Luis G.
TI Applications of a New Silicone-acrylic Hybrid Semiocclusive Drape With
   Negative Pressure Wound Therapies in a Burn Center
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE negative pressure wound therapy; wounds; silicone; acrylic; occlusive
   drape
AB It is essential that occlusive drapes provide both an airtight, watertight seal and prevent intrusion of the external environment into a healing wound bed. Removal of an acrylic drape, however, may result in pain, reflex erythema, and a denuding of the epidermis, including the stratum corneum. Recently, a new silicone-acrylic hybrid drape was introduced for use with negative pressure wound therapy. Five unique and varied clinical cases from a burn center that used such negative pressure wound therapy dressings with the silicone-acrylic hybrid drape are presented. These cases highlight the excellent sealing capabilities of this new occlusive drape and minimal pain upon its removal. In addition, this hybrid drape may decrease waste of dressing supply because it is easily reconfigured to its original form and can be repositioned if the initial placement is suboptimal. The drape also maintains a tight seal with repositioning, making it more user-friendly to the clinical provider.
C1 [Matthews, Marc R.] Arizona Burn Ctr, Surg, Phoenix, AZ 85008 USA.
   [Fernandez, Luis G.] Univ Texas Hlth Sci Ctr, Dept Surg, Surg, Tyler, TX USA.
   [Fernandez, Luis G.] UT Hlth East, Trauma Wound Care, Tyler, TX USA.
C3 University of Texas System; University of Texas at Tyler; University of
   Texas-Health Sciences Center at Tyler (UTHSCT)
RP Matthews, MR (通讯作者)，Arizona Burn Ctr, 2601 East Roosevelt St, Phoenix, AZ 85008 USA.
EM azmrmltc@gmail.com
CR [Anonymous], 2019, KCI ANN SIGN ADV NEG
   Ballard K, 2000, Br J Nurs, V9, P405
   Dykes P J, 2001, J Wound Care, V10, P7
   Dykes P J, 2007, J Wound Care, V16, P97
   Hollingworth H, 2009, TRAUMA PAIN WOUND CA, P87
   KCI an Acelity Company, 2019, DERMC DRAP PROD BROC
   Kilbride KE, 2006, J PEDIATR SURG, V41, P212, DOI 10.1016/j.jpedsurg.2005.10.003
   Matsumura H, 2014, INT WOUND J, V11, P50, DOI 10.1111/j.1742-481X.2012.01061.x
   Rippon MG, 2007, EUROPEAN WOUND MANAG
NR 9
TC 2
Z9 2
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD MAY
PY 2022
VL 34
IS 5
BP 141
EP 145
DI 10.25270/wnds/082421.02
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA D0PH5
UT WOS:000965827900003
PM 35839159
DA 2026-07-24
ER

PT J
AU Kamata, T
   Yoshida, S
   Hirai, Y
   Karita, R
   Onozato, Y
   Wada, H
   Anayama, T
AF Kamata, Toshiko
   Yoshida, Shigetoshi
   Hirai, Yuki
   Karita, Ryo
   Onozato, Yuki
   Wada, Hironobu
   Anayama, Takashi
TI Case Series of Blowhole Creation with or without Negative Pressure Wound
   Therapy for Severe Subcutaneous Emphysema
SO ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
DE blowhole; negative pressure wound therapy; subcutaneous emphysema; Japan
AB Severe subcutaneous emphysema that is refractory to chest tube drainage can result in significant patient discomfort, airway compromise, and hemodynamic instability. Various interventional approaches, including subcutaneous drain insertion and the blowhole technique, with or without negative pressure wound therapy (NPWT), have been proposed to manage this condition. In this case series, we describe 10 patients who developed severe subcutaneous emphysema following surgery or pneumothorax and were treated using the blowhole technique, with or without NPWT. A Wound Protector/Retractor XXS or LapProtector was used to maintain the patency of the blowhole, facilitating continuous decompression. In cases with more extensive emphysema, the application of NPWT led to rapid respiratory improvement, thereby enabling additional invasive interventions to address the underlying pulmonary air leak. These findings highlight the potential utility of a structured approach incorporating NPWT for the management of severe subcutaneous emphysema, particularly in cases refractory to conventional chest tube drainage.
C1 [Kamata, Toshiko; Yoshida, Shigetoshi; Onozato, Yuki; Wada, Hironobu; Anayama, Takashi] Int Univ Hlth & Welf, Sch Med, Dept Thorac Surg, 4-3 Kozunomori, Narita, Chiba 2868686, Japan.
   [Kamata, Toshiko] Int Univ Hlth & Welf, Atami Hosp, Dept Thorac Surg, Atami, Shizuoka, Japan.
   [Yoshida, Shigetoshi; Hirai, Yuki; Karita, Ryo; Onozato, Yuki; Wada, Hironobu; Anayama, Takashi] Int Univ Hlth & Welf, Narita Hosp, Dept Thorac Surg, Narita, Chiba, Japan.
C3 International University of Health & Welfare; International University
   of Health & Welfare; International University of Health & Welfare
RP Yoshida, S (通讯作者)，Int Univ Hlth & Welf, Sch Med, Dept Thorac Surg, 4-3 Kozunomori, Narita, Chiba 2868686, Japan.
EM shigeyoshida@iuhw.ac.jp
RI ; Karita, Ryo/IYJ-4815-2023; Onozato, Yuki/GYJ-0819-2022
OI Wada, Hironobu/0000-0002-5691-4886; Karita, Ryo/0009-0000-5911-4799; 
CR Bouwmeester NH, 2020, SAGE OPEN MED CASE R, V8, DOI 10.1177/2050313X20918989
   Fernandez L, 2024, Trauma Case Rep, V51
   Huan NC, 2020, RESPIROL CASE REP, V8, DOI 10.1002/rcr2.544
   Janssen N, 2022, J THORAC DIS, V14, P43, DOI 10.21037/jtd-21-1483
   Johnson CHN, 2014, INTERACT CARDIOV TH, V18, P825, DOI 10.1093/icvts/ivt532
   Mihanovia J, 2017, TRAUMA CASE REP, V13, P42
   Prakash M, 2021, ANZ J SURG, V91, P194, DOI 10.1111/ans.16365
   Sciortino Christopher M, 2009, Eplasty, V9, pe1
   Son BS, 2014, INTERACT CARDIOV TH, V19, P904, DOI 10.1093/icvts/ivu287
   Taylor BC, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.7399
   Towe C, 2014, BMJ Case Rep, V2014
NR 11
TC 0
Z9 0
U1 0
U2 2
PU Int Acad Publishing Co Ltd
PI Tokyo
PA Academy center, 358-5 yamabukicho, shinjuku-ku, Tokyo, JAPAN
SN 1341-1098
EI 2186-1005
J9 ANN THORAC CARDIOVAS
JI Ann. Thorac. Cardiovasc. Surg.
PY 2025
VL 31
IS 1
AR 2500034
DI 10.5761/atcs.cr.25-00034
PG 6
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 3ED7P
UT WOS:001498189200001
PM 40436767
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Sreelesh, LS
   Bhandari, PL
AF Sreelesh, L. S.
   Bhandari, P. Laxminarayan
TI An Easy Technique for Negative-Pressure Wound Therapy for Extremities
   Using Collagen Powder and Sterile Gloves
SO INDIAN JOURNAL OF SURGERY
LA English
DT Article
DE Negative-pressure wound therapy; Collagen; Sterile gloves; Extremity VAC
AB Negative-pressure wound therapy (NPWT) has become the standard of care for wound management. Application of NPWT to the hand and foot is technically challenging due to difficulty in obtaining a proper air seal. The cost of the treatment is another negative factor affecting NPWT in developing countries. We describe an easy and economical technique for the application of NPWT to the extremities using collage powder and sterile surgical glove. Collagen creates a physiological interface between the wound surface and the environment and is also non-immunogenic, non-pyrogenic, hypoallergenic, and pain-free. We used this method in 20 patients. In all cases, we could achieve a proper air seal and significantly reduce the cost. The median duration of NPWT application was 9 days. This combination turned out to be a good alternative to traditional VAC with respect to the duration and cost of treatment and also ergonomically better in the management of extremity wounds.
C1 [Sreelesh, L. S.; Bhandari, P. Laxminarayan] Govt Med Coll, Dept Plast Surg, Kozhikode 673008, Kerala, India.
RP Sreelesh, LS (通讯作者)，Govt Med Coll, Dept Plast Surg, Kozhikode 673008, Kerala, India.
EM sreeleshls@yahoo.com
RI Bhandari, Panambur Laxminarayan/AAW-4512-2020
CR Hemmanur SR, 2013, ARCH PLAST SURG-APS, V40, P630, DOI 10.5999/aps.2013.40.5.630
   Nataraj C, 2007, WOUNDS, V19, P148
   Ng R, 2006, J PLAST RECONSTR AES, V59, P1011, DOI 10.1016/j.bjps.2006.02.002
   NODA K, 1984, GANN, V75, P109
   Tauro LF, 2007, INDIAN J PLAST SURG, V40, P133, DOI 10.4103/0970-0358.33429
NR 5
TC 7
Z9 8
U1 0
U2 1
PU SPRINGER INDIA
PI NEW DELHI
PA 7TH FLOOR, VIJAYA BUILDING, 17, BARAKHAMBA ROAD, NEW DELHI, 110 001,
   INDIA
SN 0972-2068
EI 0973-9793
J9 INDIAN J SURG
JI Indian J. Surg
PD FEB
PY 2017
VL 79
IS 1
BP 81
EP 83
DI 10.1007/s12262-017-1589-z
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EP2TM
UT WOS:000397236200020
PM 28331276
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Onderkova, A
   Butler, PEM
   Kalavrezos, N
AF Onderkova, Anna
   Butler, Peter E. M.
   Kalavrezos, Nicholas
TI The efficacy of negative-pressure wound therapy for head and neck
   wounds: A systematic review and update
SO HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND
   NECK
LA English
DT Review
DE head and neck wounds; negative-pressure wound therapy; systematic
   review; wound healing
ID THICKNESS SKIN-GRAFTS; SPACE INFECTIONS; MANAGEMENT; FLAP
AB Despite the established benefits of negative-pressure wound therapy (NPWT) in various wound healing contexts, its application in head and neck surgical cases remains under-explored. This study aimed to systematically review its effectiveness, safety, and comparative efficacy. Thirty-one studies from a systematic literature search were identified and analyzed for wound healing response, overall success rate, improvements compared to conventional wound care, and variation in pressure settings, treatment lengths, and dressing change frequency. NPWT showed enhanced outcomes across diverse head and neck wounds, particularly complex post-reconstructive wounds and severe infections. Despite the predominantly case report/series evidence and lack of standardized NPWT protocols, its benefits over conventional care were clear. NPWT emerges as a promising approach for head and neck wound management, potentially improving patient outcomes and reducing complications. More randomized controlled trials are needed to solidify the evidence and standardize NPWT application protocols.
C1 [Onderkova, Anna; Butler, Peter E. M.] Royal Free Hosp, Charles Wolfson Ctr Reconstruct Surg, London, England.
   [Onderkova, Anna; Kalavrezos, Nicholas] Univ Coll London Hosp UCLH, Dept Head & Neck, London, England.
   [Butler, Peter E. M.] Royal Free Hosp, Dept Plast Surg, London, England.
   [Onderkova, Anna] Royal Free Hosp, Charles Wolfson Ctr Reconstruct Surg, London, England.
C3 University of London; University College London; Royal Free London NHS
   Foundation Trust; UCL Medical School; University College London
   Hospitals NHS Foundation Trust; University of London; University College
   London; UCL Medical School; Royal Free London NHS Foundation Trust;
   University of London; University College London; UCL Medical School;
   Royal Free London NHS Foundation Trust
RP Onderkova, A (通讯作者)，Royal Free Hosp, Charles Wolfson Ctr Reconstruct Surg, London, England.
EM annaonderkova@doctors.org.uk
RI Onderková, Anna/HDO-7019-2022
OI Onderková, Anna/0000-0002-4383-3040; Butler, Peter/0000-0001-7419-1493
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   Eckstein FM, 2019, J CRANIO MAXILL SURG, V47, P389, DOI 10.1016/j.jcms.2018.12.006
   Faisal M, 2021, CANCERS, V13, DOI 10.3390/cancers13102482
   Fukushima S, 2020, J WOUND CARE, V29, P568, DOI 10.12968/jowc.2020.29.10.568
   Gheuens L, 2020, INT J PEDIATR OTORHI, V138, DOI 10.1016/j.ijporl.2020.110195
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   Lin PY, 2018, LARYNGOSCOPE, V128, P2478, DOI 10.1002/lary.27169
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   Ngo CV, 2022, CHIRURGIA-ITALY, V35, P197, DOI 10.23736/S0394-9508.21.05307-9
   Ni ZM, 2020, SURG INFECT, V21, P722, DOI 10.1089/sur.2019.184
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   Pines G, 2020, INNOVATIONS, V15, P481, DOI 10.1177/1556984520935535
   Qian YY, 2022, WORLD J SURG, V46, P2973, DOI 10.1007/s00268-022-06758-9
   Satteson ES, 2015, J CRANIOFAC SURG, V26, pE599, DOI 10.1097/SCS.0000000000002047
   Slim K, 2003, ANZ J SURG, V73, P712, DOI 10.1046/j.1445-2197.2003.02748.x
   Steinbichler TB, 2021, HEAD NECK-J SCI SPEC, V43, P2377, DOI 10.1002/hed.26684
   Thierauf J, 2018, LARYNGO RHINO OTOL, V97, P474, DOI 10.1055/a-0606-5166
   Tian CH, 2021, INFECT DRUG RESIST, V14, P4765, DOI 10.2147/IDR.S337833
   Umezawa H, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001885
NR 43
TC 6
Z9 9
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1043-3074
EI 1097-0347
J9 HEAD NECK-J SCI SPEC
JI Head Neck-J. Sci. Spec. Head Neck
PD DEC
PY 2023
VL 45
IS 12
BP 3168
EP 3179
DI 10.1002/hed.27547
EA OCT 2023
PG 12
WC Otorhinolaryngology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology; Surgery
GA X7PI4
UT WOS:001086035200001
PM 37860929
OA hybrid
DA 2026-07-24
ER

PT J
AU Kimura, M
   Nawata, K
   Kinoshita, O
   Hatano, M
   Imamura, T
   Kinugawa, K
   Ono, M
AF Kimura, Mitsutoshi
   Nawata, Kan
   Kinoshita, Osamu
   Hatano, Masaru
   Imamura, Teruhiko
   Kinugawa, Koichiro
   Ono, Minoru
TI Successful Treatment of Intractable Fluid Retention Using Tolvaptan
   After Treatment for Postoperative Mediastinitis in a Patient With a Left
   Ventricular Assist Device
SO INTERNATIONAL HEART JOURNAL
LA English
DT Article
DE Congestive symptom; Hyponatremia; Volume overload negative-pressure
   wound therapy
ID HEART-FAILURE; URINE OSMOLALITY; EXPERIENCE; TRANSPLANTATION;
   ANTAGONIST; SINGLE; BRIDGE; TRIAL
AB The use of implantable continuous-flow left ventricular assist devices (LVADs) as a bridge to transplant is effective for patients with congestive heart failure (I-IF). However, some patients develop congestive symptoms due to right-sided 11F even with LVAD support. Tolvaptan, a vasopressin type 2 receptor antagonist, corrects both congestion and hyponatremia in patients with advanced HE We report herein a case involving a patient who underwent LVAD implantation and developed hyponatremia and congestive symptoms after negative-pressure wound therapy and omental transposition for postoperative mediastinitis. Hemodynarnic evaluation performed after negative-pressure wound therapy revealed elevation of both right arterial pressure and pulmonary capillary wedge pressure, and suggested biventricular dysfunction despite LVAD support. Symptoms improved after starting administration of tolvaptan. Tolvaptan may be useful for correcting hyponatremia and volume overload in patients under LVAD support.
C1 [Kimura, Mitsutoshi; Nawata, Kan; Kinoshita, Osamu; Ono, Minoru] Univ Tokyo, Grad Sch Med, Dept Cardiac Surg, Tokyo 1138655, Japan.
   [Hatano, Masaru] Univ Tokyo, Grad Sch Med, Dept Cardiovasc Med, Tokyo 1138655, Japan.
   [Imamura, Teruhiko; Kinugawa, Koichiro] Univ Tokyo, Grad Sch Med, Dept Therapeut Strategy Heart Failure, Tokyo 1138655, Japan.
C3 University of Tokyo; University of Tokyo; University of Tokyo
RP Ono, M (通讯作者)，Univ Tokyo, Grad Sch Med, Dept Cardiac Surg, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan.
EM ono-tho@h.u-tokyo.ac.jp
RI ; Imamura, Teruhiko/AFD-8074-2022; Nawata, Kan/AAD-7153-2020
OI Kimura, Mitsutoshi/0009-0007-9071-4400; 
FU Otsuka Pharmaceutical (Tokyo); Grants-in-Aid for Scientific Research
   [15K09065] Funding Source: KAKEN
FX Dr. Teruhiko Imamura and Dr. Koichiro Kinugawa belong to the Department
   of Therapeutic Strategy for Heart Failure, which is an endowed
   department sponsored by 13 companies including Otsuka Pharmaceutical
   (Tokyo). Koichiro Kinugawa was a consultant for Otsuka Pharmaceutical
   and has received honoraria from Otsuka Pharmaceutical for lectures. The
   other authors have no conflicts of interest to declare.
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NR 18
TC 6
Z9 6
U1 0
U2 2
PU INT HEART JOURNAL ASSOC
PI TOKYO
PA UNIV TOKYO, GRADUATE SCHOOL MEDICINE, DEPT CARDIOVASCULAR MEDICINE,
   HONGO 7-3-1, BUNKYO-KU, TOKYO, 113-8655, JAPAN
SN 1349-2365
EI 1349-3299
J9 INT HEART J
JI Int. Heart J.
PD SEP
PY 2015
VL 56
IS 5
BP 574
EP 577
DI 10.1536/ihj.14-412
PG 4
WC Cardiac & Cardiovascular Systems
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA CX1LR
UT WOS:000365458200020
PM 26370363
OA Bronze
DA 2026-07-24
ER

PT J
AU Magalini, S
   Pepe, G
   Cozza, V
   Tilli, P
   La Greca, A
   Longo, F
   Gui, D
AF Magalini, S.
   Pepe, G.
   Cozza, V.
   Tilli, P.
   La Greca, A.
   Longo, F.
   Gui, D.
TI Negative pressure wound therapy (NPWT) in duodenal breakdown fistulas:
   negative pressure fistula therapy (NPFT)?
SO EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
LA English
DT Article
DE NPWT; Negative pressure; Wound therapy; Duodenal fistula
ID MANAGEMENT; SURGERY; COMPLICATIONS; GASTRECTOMY; CLOSURE; RESCUE
AB OBJECTIVE: To describe for the first time in literature the specific methodology of use of negative pressure wound therapy (NPWT) for duodenal fistula through clinical cases. The constant increase of use of NPWT for complex surgical situations imposes tailored previously undescribed solutions for the technique.
   PATIENTS AND METHODS: Herein, three cases of high output duodenal fistula successfully treated with Negative Pressure Wound Therapy (NPWT) are reported. The technical details for the application of NPWT to these fistulas are discussed and described.
   RESULTS: All three patients recovered without the necessity of further surgical operations.
   CONCLUSIONS: When using NPWT, management of high-output duodenal fistulas must rely on some degree of customization of the aspiration systems. The aim of the procedure is to put under depression the duodenal hole and surrounding tissues "all in one" and not to separate the complex wound in sectors as usually indicated. We suggest calling this technique Negative Pressure Fistula Therapy.
C1 [Magalini, S.; Pepe, G.; Cozza, V.; La Greca, A.; Longo, F.; Gui, D.] Univ Cattolica Sacro Cuore, Emergency Surg Dept, Fdn Policlin A Gemelli, Sch Med, Rome, Italy.
   [Tilli, P.] Univ Cattolica Sacro Cuore, Sch Med, Emergency Med Dept, Fdn Policlin A Gemelli, Rome, Italy.
C3 Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli;
   Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli
RP Pepe, G (通讯作者)，Univ Cattolica Sacro Cuore, Emergency Surg Dept, Fdn Policlin A Gemelli, Sch Med, Rome, Italy.
EM gildapepe@yahoo.it
RI La Greca, Antonio/V-2593-2018; Longo, Francesco/AAE-5148-2021
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   Jannasch O., 2014, NEGAT PRESS WOUND, V1, P112
   Kocakusak A, 2017, EUR REV MED PHARMACO, V21, P150
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NR 26
TC 5
Z9 7
U1 0
U2 6
PU VERDUCI PUBLISHER
PI ROME
PA VIA GREGORIO VII, ROME, 186-00165, ITALY
SN 1128-3602
J9 EUR REV MED PHARMACO
JI Eur. Rev. Med. Pharmacol. Sci.
PD MAY
PY 2017
VL 21
IS 10
BP 2452
EP 2457
PG 6
WC Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pharmacology & Pharmacy
GA EZ3ZP
UT WOS:000404650900021
PM 28617541
DA 2026-07-24
ER

PT J
AU Tabayashi, N
   Yoshikawa, Y
   Abe, T
   Naito, H
   Hayata, Y
   Hirose, T
   Yamashita, K
   Taniguchi, S
AF Tabayashi, Nobuoki
   Yoshikawa, Yoshiro
   Abe, Takehisa
   Naito, Hiroshi
   Hayata, Yosihiro
   Hirose, Tomoaki
   Yamashita, Keigo
   Taniguchi, Shigeki
TI PREVENTION OF ABDOMINAL COMPARTMENT SYNDROME AFTER RUPTURED ABDOMINAL
   AORTIC ANEURYSM REPAIR - IMPACT OF INTRA-ABDOMINAL PRESSURE MONITORING
   AND OPEN WOUND WITH VACUUM ASSISTED CLOSURE TECHNIQUE
SO ACTA CLINICA BELGICA
LA English
DT Meeting Abstract
C1 [Tabayashi, Nobuoki; Yoshikawa, Yoshiro; Abe, Takehisa; Naito, Hiroshi; Hayata, Yosihiro; Hirose, Tomoaki; Yamashita, Keigo; Taniguchi, Shigeki] Nara Med Univ, Dept Thorac & Cardiovasc Surg, Nara, Japan.
C3 Nara Medical University
NR 0
TC 0
Z9 0
U1 0
U2 1
PU ACTA CLINICA BELGICA
PI GHENT
PA UNIV HOSPITAL GENT, DE PINTELAAN 185, RENAL DIVISION, B-9000 GHENT,
   BELGIUM
SN 0001-5512
J9 ACTA CLIN BELG
JI Acta Clin. Belg.
PD MAY-JUN
PY 2009
VL 64
IS 3
BP 273
EP 273
PG 1
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 468VN
UT WOS:000267852400134
DA 2026-07-24
ER

PT J
AU Smid, MC
   Dotters-Katz, SK
   Grace, M
   Wright, ST
   Villers, MS
   Hardy-Fairbanks, A
   Stamilio, DM
AF Smid, Marcela C.
   Dotters-Katz, Sarah K.
   Grace, Matthew
   Wright, Sarah T.
   Villers, Margaret S.
   Hardy-Fairbanks, Abbey
   Stamilio, David M.
TI Prophylactic Negative Pressure Wound Therapy for Obese Women After
   Cesarean Delivery A Systematic Review and Meta-analysis
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Review
ID SURGICAL SITE INFECTIONS; RANDOMIZED CONTROLLED-TRIAL; EXTREME OBESITY;
   COMPLICATIONS; SECTION; CEFAZOLIN; OUTCOMES
AB OBJECTIVE: To summarize available studies on wound complication outcomes after prophylactic negative pressure wound therapy for obese women (body mass index 30 or greater).
   DATA SOURCES: We conducted a systematic review and meta-analysis using electronic database search (PubMed, Cumulative Index to Nursing and Allied Health Literature, EMBASE, Google scholar, and Web of Science), Cochrane, and trial registries including ClinicalTrials.gov.
   METHODS OF STUDY SELECTION: We conducted an electronic search of research articles from 1966 to January 2017 for randomized controlled trials (RCTs), prospective cohort, and retrospective cohort studies of negative pressure wound therapy compared with standard dressing after cesarean delivery among obese women. Our primary outcome was defined as a composite of wound complication, including wound or surgical site infection, cellulitis, seroma, hematoma, wound disruption, or dehiscence. For cohort studies and RCTs, we performed a descriptive systematic review. For available RCTs, we performed a meta-analysis and pooled risk ratios using a random-effects model. We assessed for heterogeneity using chi(2) test for heterogeneity and I-2 test. We assessed for publication bias using a funnel plot.
   TABULATION, INTEGRATION, AND RESULTS: Of 10 studies meeting eligibility criteria, five were RCTs and five were cohort studies. Results of cohort studies were varied; however, all had a high potential for selection bias. In the meta-analysis, there was no difference in primary composite outcome among those women with negative pressure wound therapy (16.8%) compared with those who had standard dressing (17.8%) (risk ratio 0.97, 95% CI 0.63-1.49). There was no statistically significant heterogeneity (chi(2) test 4.80, P=.31, I-2=17%).
   CONCLUSION: Currently available evidence does not support negative pressure wound therapy use among obese women for cesarean wound complication prevention.
C1 Univ Utah, Dept Obstet & Gynecol, Div Maternal Fetal Med, Salt Lake City, UT USA.
   Univ North Carolina Chapel Hill, Div Maternal Fetal Med, Dept Obstet & Gynecol, Chapel Hill, NC USA.
   Univ North Carolina Chapel Hill, Hlth Sci Lib, Chapel Hill, NC USA.
   Duke Univ, Dept Obstet & Gynecol, Div Maternal Fetal Med, Durham, NC USA.
   Univ Iowa, Div Maternal Fetal Med, Dept Obstet & Gynecol, Iowa City, IA USA.
C3 Utah System of Higher Education; University of Utah; University of North
   Carolina; University of North Carolina Chapel Hill; University of North
   Carolina School of Medicine; University of North Carolina; University of
   North Carolina Chapel Hill; University of North Carolina School of
   Medicine; Duke University; University of Iowa
RP Smid, MC (通讯作者)，Univ Utah, 30 N 1900 E,2B200, Salt Lake City, UT 84312 USA.
EM Marcela.Smid@hsc.utah.edu
RI ; Grace, Matthew/GYD-4980-2022; Wright, Sarah/P-8166-2016; Wright,
   Sarah/P-8166-2016
OI Hardy-Fairbanks, Abbey/0000-0003-4041-3937; Grace,
   Matthew/0000-0003-3654-0677; Wright, Sarah/0000-0003-2076-8343
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NR 44
TC 48
Z9 53
U1 0
U2 9
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0029-7844
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD NOV
PY 2017
VL 130
IS 5
BP 969
EP 978
DI 10.1097/AOG.0000000000002259
PG 10
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA FP5HS
UT WOS:000417651200018
PM 29016508
DA 2026-07-24
ER

PT J
AU Reed, T
   Economon, D
   Wiersema-Bryant, L
AF Reed, T
   Economon, D
   Wiersema-Bryant, L
TI Colocutaneous fistula management in a dehisced wound: A case study
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE fistula; wound dehiscence; negative pressure wound therapy; drainage
ID ENTEROCUTANEOUS FISTULAS
AB A fistula is an abnormal opening between two or more organs or structures. Wound drainage containment is a key component of nonsurgical fistula management and may include pouches, skin barriers, transparent dressings, troughing procedures, saddle bagging, bridging, and condom and suction catheters used in combination with complex or routine pouching. Following extensive abdominal surgery, the wound of a 50-year-old woman dehisced and a colocutaneous fistula formed inside the wound. The wound containing the fistula, which was draining liquid stool, was too large for existing commercial pouching systems. When initial management efforts, including negative pressure wound therapy, failed to achieve containment goals, clinicians adapted the negative pressure wound therapy dressing to surround the fistula, which helped facilitate therapy while providing a platform for an ostomy appliance to contain the fistula drainage. The system was changed every 2 days until discharge. The wound and fistula management combination improved patient comfort and mobility, facilitated healing, and reduced patient dietary restrictions.
C1 Barnes Jewish Hosp, BJC Hlth Care, St Louis, MO 63110 USA.
C3 Barnes-Jewish Hospital; Washington University (WUSTL)
RP Reed, T (通讯作者)，Barnes Jewish Hosp, BJC Hlth Care, St Louis, MO 63110 USA.
EM txr9446@bjc.org
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   MCKEE M, MANAGEMENT COMPLEX O
NR 8
TC 8
Z9 8
U1 0
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD APR
PY 2006
VL 52
IS 4
BP 60
EP +
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 036AY
UT WOS:000237044400012
PM 16636363
DA 2026-07-24
ER

PT J
AU Vilkins, A
   Nherera, L
   Searle, R
   Welsh, T
AF Vilkins, Annmarie
   Nherera, Leo
   Searle, Richard
   Welsh, Tia
TI Comparison of the Effectiveness of Two Prophylactic Single-Use Negative
   Pressure Wound Therapy Devices in Reducing Surgical Site Complications
   After Cesarean Delivery: Insights From a Large US Claims Database
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE single-use negative pressure wound therapy; surgical site complications;
   surgical site infections; cesarean delivery; real-world evidence
ID INFECTION; SECTION
AB Background. Single-use negative pressure wound therapy (sNPWT) has emerged as a promising intervention for patients at high risk of surgical site complications (SSCs) after a cesarean delivery. However, the available studies primarily compare negative pressure wound therapy to standard dressings rather than evaluating differences between negative pressure wound therapy devices or pressure settings. Objective. To compare the effectiveness of 2 commonly used sNPWT devices, a -80 mm Hg device and a -125 mm Hg device, in reducing the risk of SSCs following cesarean delivery. Materials and Methods. Real-world data were obtained from a large claims database in the United States from January 2017 through June 2022. Adult patients who had an inpatient encounter in which the -80 mm Hg device or the -125 mm Hg device was used after a cesarean delivery were included. Propensity score matching was used to balance the cohorts. Study end points included incidence of overall surgical site infection (SSI), superficial SSI, dehiscence, seroma, hematoma, deep SSI, length of stay (LOS), and costs. Results. The study included 5332 cases in each group. Overall SSI, superficial SSI, dehiscence, seroma, and costs were significantly lower with the -80 mm Hg device compared with the -125 mm Hg device (P <= .05). No differences between the 2 devices were observed for hematoma, deep SSI, and LOS (P > .05). Conclusion. Of the 2 commonly used sNPWT devices, use of the -80 mm Hg device was associated with a lower likelihood of developing overall SSI, superficial SSI, dehiscence, and seroma, and was associated with lower costs after cesarean delivery compared with the -125 mm Hg device. There were nonsignificant differences in LOS, deep SSI, and hematoma. Further studies are required to confirm these findings.
C1 [Vilkins, Annmarie] Henry Ford Med Ctr, Detroit, MI USA.
   [Nherera, Leo; Searle, Richard] Smith Nephew, Ft Worth, TX USA.
   [Welsh, Tia] Valley Hlth Syst, Ridgewood, NJ USA.
C3 Henry Ford Health System; Smith & Nephew
RP Welsh, T (通讯作者)，Valley Hlth Syst, Obstet & Gynecol, 223 N Dien Ave, Ridgewood, NJ 07450 USA.
EM welsti@Valleyhealth.com
FU Smith + Nephew, Inc.
FX Funding: This study was funded by Smith + Nephew, Inc.
CR American Hospital Association, 2016, Trends in inpatient utilization in community hospitals, 1995-2016
   [Anonymous], 2019, MedTech Innovation Briefing
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   Hamilton B.E., 2020, Births: Provisional data for 2021
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   Olsen MA, 2010, INFECT CONT HOSP EP, V31, P276, DOI 10.1086/650755
   PINC AITM Applied Sciences PI, 2020, PINC AITM Healthcare Database: Data That Informs and Performs
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NR 31
TC 0
Z9 0
U1 1
U2 1
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2025
VL 37
IS 4
DI 10.25270/wnds/24183
PG 11
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 3KV6M
UT WOS:001502754300003
PM 40368390
DA 2026-07-24
ER

PT J
AU Bonds, AM
   Novick, TK
   Dietert, JB
   Araghizadeh, FY
   Olson, CH
AF Bonds, Allison M.
   Novick, Tessa K.
   Dietert, Jessica B.
   Araghizadeh, Farshid Y.
   Olson, Craig H.
TI Incisional Negative Pressure Wound Therapy Significantly Reduces
   Surgical Site Infection in Open Colorectal Surgery
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article
DE Wound closure; Wound healing; Outcomes research; Colon and rectal
   surgery
ID PERIOPERATIVE INTRAPERITONEAL CHEMOTHERAPY; SYNCHRONOUS PERITONEAL
   CARCINOMATOSIS; CYTOREDUCTIVE SURGERY; LIVER METASTASES; HYPERTHERMIC
   CHEMOTHERAPY; CANCER PATIENTS; ORIGIN; SURVIVAL; OUTCOMES;
   CHEMOHYPERTHERMIA
AB BACKGROUND: Surgical site infections in colorectal surgery remain a common problem, and are associated with an increase in cost of care and length of stay.
   OBJECTIVE: This study aims to evaluate the effect of known risk factors and the use of incisional negative pressure wound therapy on surgical site infection rates.
   DESIGN: This is a single-center retrospective study with the use of chart review.
   SETTINGS: The study took place at a tertiary academic medical center.
   PATIENTS: All patients undergoing open colectomy at a single institution from 2009 through 2011 were studied.
   MAIN OUTCOME MEASURES: The primary outcome measured was the presence or absence of surgical site infection.
   RESULTS: Overall, 69 of the 254 patients (27.2%) experienced surgical site infection; 4 (12.5%) surgical site infections were seen in patients undergoing incisional negative pressure wound therapy and 65 (29.3%) were seen in patients undergoing standard closure. Multiple logistic regression revealed 2 significant factors: diabetes mellitus increased the chance of surgical site infection (OR, 1.98; p < 0.05), and the use of incisional negative pressure wound therapy decreased the chance of surgical site infection (OR, 0.32; p < 0.05). Obesity was associated with a trend toward increasing surgical site infection (OR, 1.64; p = 0.10).
   LIMITATIONS: This study is limited by its retrospective nature and the high baseline prevalence of surgical site infection.
   CONCLUSIONS: Incisional negative pressure wound therapy appears to reduce surgical site infection in open colorectal surgery. Further study may be helpful to identify patient populations who would have the greatest benefit from this technique (see Video, Supplemental Digital Content 1, http://links.lww.com/DCR/A115).
C1 [Bonds, Allison M.; Novick, Tessa K.; Dietert, Jessica B.; Araghizadeh, Farshid Y.; Olson, Craig H.] Univ Texas Southwestern, Sect Colorectal Surg, Dept Surg, Dallas, TX 75390 USA.
C3 University of Texas System; University of Texas Southwestern Medical
   Center
RP Olson, CH (通讯作者)，Univ Texas Southwestern, 1801 Inwood Rd,Ste WA4 416, Dallas, TX 75390 USA.
EM Craig.Olson@utsouthwestern.edu
OI Novick, Tessa/0000-0002-5659-8772
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   Glehen O, 2010, CANCER-AM CANCER SOC, V116, P5608, DOI 10.1002/cncr.25356
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NR 39
TC 87
Z9 97
U1 0
U2 9
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD DEC
PY 2013
VL 56
IS 12
BP 1403
EP 1408
DI 10.1097/DCR.0b013e3182a39959
PG 6
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 292SR
UT WOS:000329923200013
PM 24201395
DA 2026-07-24
ER

PT J
AU Singh, PK
   Sethi, MK
   Mishra, TS
   Kumar, P
   Ali, SM
   Sasmal, PK
AF Singh, Pradeep K.
   Sethi, Mahesh K.
   Mishra, Tushar S.
   Kumar, Pankaj
   Ali, S. Manwar
   Sasmal, Prakash Kumar
TI Comparison of Surgical Site Infection Between Conventional and Negative
   Pressure Wound Therapy-Assisted Delayed Primary Skin Closure in Grossly
   Contaminated Emergency Abdominal Surgeries: A Randomized Controlled
   Trial
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Meeting Abstract
C1 All India Inst Med Sci, Bhubaneswar, India.
   All India Inst Med Sci, Bhubaneswar, Odisha, India.
C3 All India Institute of Medical Sciences (AIIMS) Bhubaneswar; All India
   Institute of Medical Sciences (AIIMS) Bhubaneswar
RI MISHRA, TUSHAR/KFS-1512-2024
NR 0
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD NOV
PY 2022
VL 235
IS 5
SU 2
BP S30
EP S30
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 5H7TK
UT WOS:000867877000072
DA 2026-07-24
ER

PT J
AU He, S
   Tang, N
   Li, S
AF He, Si
   Tang, Na
   Li, Sha
TI Comparison of negative pressure wound therapy with conventional wound
   care in the treatment of sternal wound infection after cardiac surgery:
   A meta-analysis with trial sequential analysis
SO PLOS ONE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; POST-STERNOTOMY MEDIASTINITIS; CARDIOTHORACIC
   SURGERY; INCISION MANAGEMENT; PREVENTION; SYSTEM; BIAS
AB Background Negative pressure wound therapy (NPWT) has become a popular treatment option for sternal wound infection (SWI). However, it remains uncertain whether the therapeutic benefits of NPWT are superior to conventional wound care. This study aimed to systematically evaluate the therapeutic effects of NPWT on SWI compared to conventional wound care through meta-analysis. Methods A comprehensive search of PubMed, Web of Science, Embase, and the Cochrane Library databases was conducted from inception to April 29, 2024 for all potential studies. The pooling of dichotomous outcome data was achieved using relative risk (RR), with results presented within a 95% confidence interval (CI). We utilized the standard mean difference (SMD) and 95% CI for continuous outcomes. Heterogeneity test, publication bias assessment, sensitivity analysis, and trial sequential analysis (TSA) were conducted. Publication bias was detected through the Begg's and Egger's tests. Software R 4.3.1, Stata 12.0, and TSA v0.9.5.10 Beta software were utilized for all analyses. Results Out of 1832 articles identified, 10 were included in this study. The overall results revealed that NPWT significantly decreased the sternal wound reinfection (SWRI) rate (RR [95% CI] = 0.179 [0.099 to 0.323], 95% prediction interval [PI]: 0.082 to 0.442), in-hospital mortality (RR [95% CI] = 0.242 [0.149 to 0.394], 95% PI: 0.144 to 0.461), and shortened the length of intensive care unit (ICU) stay (SMD [95% CI] = -0.601 [-0.820 to -0.382], 95% PI: -1.317 to 0.128) compared with conventional wound care. There was no significant difference in length of hospital stay (SMD [95% CI] = -0.402 [-0.815 to 0.012], 95% PI: -1.801 to 0.998) and treatment duration (SMD [95% CI] = -0.398 [-1.646 to 0.849], 95% PI: -16.340 to 15.543) between the NPWT group and control group. Further subgroup analysis demonstrated the benefits of NPWT in shortening hospitalization length in the European population (p < 0.05). Conclusion The present evidence corroborates that the application of NPWT in the treatment of SWI after cardiac surgery effectively reduces the SWRI incidence and in-hospital mortality while shortening the length of ICU stay.
C1 [He, Si; Tang, Na; Li, Sha] Hunan Univ Chinese Med, Hosp Infect Management Dept, Changsha Stomatol Hosp, Stomatol Clin Coll, Changsha, Peoples R China.
C3 Hunan University of Chinese Medicine
RP Li, S (通讯作者)，Hunan Univ Chinese Med, Hosp Infect Management Dept, Changsha Stomatol Hosp, Stomatol Clin Coll, Changsha, Peoples R China.
EM 1192063955@qq.com
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NR 54
TC 1
Z9 2
U1 0
U2 0
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
EI 1932-6203
J9 PLOS ONE
JI PLoS One
PD AUG 7
PY 2025
VL 20
IS 8
AR e0328771
DI 10.1371/journal.pone.0328771
PG 16
WC Multidisciplinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Science & Technology - Other Topics
GA 5XE7X
UT WOS:001546478300040
PM 40773424
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Malmsjö, M
   Ingemansson, R
AF Malmsjo, M.
   Ingemansson, R.
TI Green foam, black foam or gauze for NWPT: effects on granulation tissue
   formation
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE experimental surgery; wound healing; negative pressure wound therapy;
   granulation tissue formation
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; NEGATIVE-PRESSURE;
   DRESSING CHANGES
AB Objective: To compare the effects of green foam with black foam and gauze during negative pressure wound therapy (NPWT), with regard to wound bed appearance and granulation tissue formation, and monitoring of wound exudate.
   Method: Wounds on the backs of eight pigs underwent 72 hours of NPWT plus either green polyurethane foam with an open pore structure, black polyurethane foam with an open pore structure or saline-moistened AMD gauze. Sections of biopsies from the wound bed, including the overlying dressing, were examined histologically with regard to microdeformation of the wound bed and granulation tissue formation. The force required to remove the wound fillers was measured.
   Results: Wound exudate and bleeding could be easily seen when using gauze and green foam, but were not visible under the black foam. Such visibility facilitates monitoring of the wound status. No difference was found in the quantity or characteristics of the granulation tissue formed under the green foam or black foam. Both green foam and black foam resulted in more pronounced granulation tissue formation than gauze under negative pressure. There was also more leucocyte infiltration and tissue disorganisation under green foam and black foam than under gauze. All three wound fillers created microdeformation within the wound bed surface. Similar forces were required to remove green foam and black foam (5.0 +/- 0.6 N for green foam and 4.0 +/- 0.4 N for black foam), while less force was needed for gauze (2.1 +/- 0.2 N). This may be a result of tissue ingrowth into the foam (357 +/- 12 mu m for green foam and 362 +/- 14 mu m for black foam), but not into gauze (0 mu m), as shown by examination of biopsy sections from the wound bed.
   Conclusion: Green foam and black foam have similar biological effects on the wound bed. Bleeding and exudate can be more easily monitored when using green foam or gauze. Differences in the wound bed tissue morphology when using foam or gauze plus NPWT support clinical observations that granulation tissue under foam is thick but fragile, whereas that under foam is thinner but denser.
C1 [Malmsjo, M.] Lund Univ, Dept Ophthalmol, Lund, Sweden.
   [Ingemansson, R.] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
   [Ingemansson, R.] Skane Univ Hosp, Lund, Sweden.
C3 Lund University; Lund University; Lund University; Skane University
   Hospital
RP Malmsjö, M (通讯作者)，Lund Univ, Dept Ophthalmol, Lund, Sweden.
EM malin.malmsjo@med.lu.se
OI Ingemansson, Richard/0000-0001-7623-8953; Maljö,
   Malin/0000-0001-9849-9599
FU Molnlycke Health Care AB
FX The study was supported by Molnlycke Health Care AB.
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NR 20
TC 13
Z9 17
U1 0
U2 9
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD JUN
PY 2011
VL 20
IS 6
BP 294
EP 299
DI 10.12968/jowc.2011.20.6.294
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 929YZ
UT WOS:000303103100008
PM 21727880
DA 2026-07-24
ER

PT J
AU Rao, M
   Burke, D
   Finan, PJ
   Sagar, PM
AF Rao, M.
   Burke, D.
   Finan, P. J.
   Sagar, P. M.
TI The use of vacuum-assisted closure of abdominal wounds: a word of
   caution
SO COLORECTAL DISEASE
LA English
DT Article
DE vacuum-assisted closure; laparostomy; abdominal closure
ID FASCIAL CLOSURE; TEMPORARY CLOSURE; VENTRAL HERNIA; PACK TECHNIQUE; OPEN
   ABDOMENS; TRAUMA
AB Objective Vacuum-assisted closure (VAC) has been used in our centre to aid the closure of abdominal wounds. The aim of this study was to examine the clinical outcome of patients in whom VAC therapy had been used in conjunction with laparostomy.
   Method All patients in whom VAC was used in the management of open abdominal wounds from November 2003 to March 2005 were included in this study.
   Results There were 29 patients in the study. Nineteen (65.5%) needed ICU care. Six (20%) patients developed leakage of small bowel contents into the abdominal wound cavity because of intestinal fistulation during the VAC therapy. Four of the six (66%) died, all from multi-organ failure.
   Conclusion Our study has demonstrated a high incidence of intestinal leakage following VAC therapy. The reasons for this are multifactorial. We would recommend caution in using it on patients with bowel anastomoses or enterotomy repairs.
C1 Gen Infirm, Dept Colorectal Surg, Leeds LS1 3EX, W Yorkshire, England.
C3 Leeds General Infirmary
RP Sagar, PM (通讯作者)，Gen Infirm, Dept Colorectal Surg, Great George St, Leeds LS1 3EX, W Yorkshire, England.
EM peter.sagar@leedsth.nhs.uk
OI Burke, Dermot/0000-0002-4342-7464
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NR 12
TC 129
Z9 146
U1 0
U2 2
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 1462-8910
J9 COLORECTAL DIS
JI Colorectal Dis.
PD MAR 3
PY 2007
VL 9
IS 3
BP 266
EP 268
DI 10.1111/j.1463-1318.2006.01154.x
PG 3
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 134IN
UT WOS:000244076800014
PM 17298627
DA 2026-07-24
ER

PT J
AU Waugh, L
   D'Agostino, J
   Cole, GA
   Hahn, A
   Day, JD
AF Waugh, Lynnette
   D'Agostino, Jennifer
   Cole, Gretchen A.
   Hahn, Alicia
   Day, Jonathan D.
TI MANAGEMENT OF PODODERMATITIS WITH AN ORTHOTIC BOOT IN A SOUTHERN ISABELA
   GIANT TORTOISE (CHELONOIDIS VICINA)
SO JOURNAL OF ZOO AND WILDLIFE MEDICINE
LA English
DT Article
DE Chelonoidis vicina; orthotic; boot; pododermatitis; total contact
   casting; vacuum-assisted closure
ID VACUUM-ASSISTED CLOSURE; WOUNDS
AB A 62-yr-old male Southern Isabela giant tortoise (Chelonoidis vicina) had a 1-yr history of chronic, reoccurring pododermatitis on the palmar surface of the left forelimb. Aggressive wound management was instituted and included surgical debridement, vacuum-assisted closure, and orthotic boot support during healing. A custom fabricated, carbon fiber clamshell Charcot Restraint Orthotic Walker walking boot was utilized to reduce focal pressure over the wound during weight bearing and promote a more normal gait. Distal padding was used to distribute pressure on the palmar surface of the left forelimb, with a focal depression in the padding preventing pressure directly over the wound. The design and trim lines were adjusted to allow shoulder and elbow motion without impingement. The clamshell design allowed relatively easy removal for wound inspection and dressing changes. The wound ultimately resolved after 9 wk of management with the orthotic boot, with no reoccurrence over the next 3 yr.
C1 [Waugh, Lynnette; D'Agostino, Jennifer; Cole, Gretchen A.; Hahn, Alicia] Oklahoma City Zoo, 2101 NE 50th St, Oklahoma City, OK 73111 USA.
   [Day, Jonathan D.] Univ Oklahoma, Coll Med, Hlth Sci Ctr, 1200 Childrens Ave, Oklahoma City, OK 73104 USA.
   [Hahn, Alicia] Pittsburgh Zoo & PPG Aquarium, 7340 Butler St, Pittsburgh, PA 15206 USA.
C3 University of Oklahoma System; University of Oklahoma Health Sciences
   Center
RP D'Agostino, J (通讯作者)，Oklahoma City Zoo, 2101 NE 50th St, Oklahoma City, OK 73111 USA.
EM jdagostino@okczoo.org
OI D'Agostino, Jennifer/0009-0001-3542-8416
CR Adkesson MJ, 2007, JAVMA-J AM VET MED A, V231, P1249, DOI 10.2460/javma.231.8.1249
   Armstrong David G, 2004, Int J Low Extrem Wounds, V3, P12, DOI 10.1177/1534734604263291
   Bezjian M, 2014, J ZOO WILDLIFE MED, V45, P428, DOI 10.1638/2013-0178R.1
   Clare MP, 2002, FOOT ANKLE INT, V23, P896, DOI 10.1177/107110070202301002
   Hawkins MG, 2012, FERRETS RABBITS RODE, P305
   Hebs L, 2012, FERRETS RABBITS RODE, P235
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   Schmidt Robert E., 2006, P395
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   Wu SC, 2007, VASC HEALTH RISK MAN, V3, P65
NR 10
TC 0
Z9 1
U1 0
U2 2
PU AMER ASSOC ZOO VETERINARIANS
PI YULEE
PA 581705 WHITE OAK ROAD, YULEE, FL 32097 USA
SN 1042-7260
EI 1937-2825
J9 J ZOO WILDLIFE MED
JI J. Zoo Wildl. Med.
PD JUN
PY 2017
VL 48
IS 2
BP 594
EP 597
DI 10.1638/2016-0185.1
PG 4
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA FB8IM
UT WOS:000406382700050
PM 28749259
DA 2026-07-24
ER

PT J
AU Berkowitz, J
   Rediske, WR
   Chance, J
   Kim, DH
AF Berkowitz, Jacob
   Rediske, William R.
   Chance, John
   Kim, David H.
TI Technique tip: Creation of a vacuum-assisted closure system for wound
   management in an austere environment
SO FOOT & ANKLE INTERNATIONAL
LA English
DT Article
ID NEGATIVE-PRESSURE; SUBATMOSPHERIC PRESSURE; SKIN-GRAFTS; EXPERIENCE;
   DRESSINGS; THERAPY; TRIAL
C1 Tripler Army Med Ctr, Honolulu, HI 96859 USA.
   Darnall Army Community Hosp, Ft Hood, TX USA.
   Kaiser Permanente, Denver, CO USA.
C3 United States Department of Defense; United States Army; Tripler Army
   Medical Center; Kaiser Permanente
RP Berkowitz, J (通讯作者)，Tripler Army Med Ctr, 1 Jarrett White Rd, Honolulu, HI 96859 USA.
EM mark.j.berkowitz@us.army.mil
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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   Clare MP, 2002, FOOT ANKLE INT, V23, P896, DOI 10.1177/107110070202301002
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
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NR 14
TC 4
Z9 4
U1 0
U2 0
PU AMER ORTHOPAEDIC FOOT & ANKLE SOC, INC
PI SEATTLE
PA 2517 EASTLAKE AVE EAST, STE 200, SEATTLE, WA 98102 USA
SN 1071-1007
J9 FOOT ANKLE INT
JI Foot Ankle Int.
PD MAR
PY 2007
VL 28
IS 3
BP 388
EP 391
DI 10.3113/FAI.2007.0388
PG 4
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 140WF
UT WOS:000244536700018
PM 17371665
DA 2026-07-24
ER

PT J
AU Roupé, KM
AF Roupe, K. Markus
TI The influence on wound contraction and fluid evacuation of a rigid disc
   inserted to protect exposed organs during negative pressure wound
   therapy (vol 8, pg 393, 2011)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Correction
RI /K-6502-2014
CR Anesäter E, 2011, INT WOUND J, V8, P393, DOI 10.1111/j.1742-481X.2011.00805.x
NR 1
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1742-4801
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2011
VL 8
IS 6
BP 661
EP 661
DI 10.1111/j.1742-481X.2011.00866.x
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 854AL
UT WOS:000297466800015
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Whitaker, IS
   Rozen, WM
   Shokrollahi, K
AF Whitaker, Iain S.
   Rozen, Warren M.
   Shokrollahi, Kayvan
TI The Management of Open Lower Limb Fractures: The Journey From Amputation
   to Evidence-Based Reconstruction and Harpsichords
SO ANNALS OF PLASTIC SURGERY
LA English
DT Editorial Material
ID VACUUM-ASSISTED CLOSURE; MICROVASCULAR ANASTOMOSES; WOUND CONTROL;
   ISLAND FLAP
C1 [Whitaker, Iain S.; Shokrollahi, Kayvan] Morriston Hosp, Welsh Ctr Burns & Plast Surg, Swansea, W Glam, Wales.
   [Rozen, Warren M.] Univ Melbourne, Dept Anat & Cell Biol, Jack Brockhoff Reconstruct Plast Surg Res Unit, Parkville, Vic 3052, Australia.
C3 Morriston Hospital; University of Melbourne
RP Whitaker, IS (通讯作者)，Morriston Hosp, Welsh Ctr Burns & Plast Surg, Swansea, W Glam, Wales.
EM iainwhitaker@fastmail.fm
RI Rozen, Warren Matthew/AAE-6296-2022; Whitaker, Iain/O-5896-2019;
   Shokrollahi, Kayvan/V-4993-2019
OI Rozen, Warren Matthew/0000-0002-4092-182X; Whitaker,
   Iain/0000-0002-3922-2079; Shokrollahi, Kayvan/0000-0003-1044-7781
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   DANIEL RK, 1973, PLAST RECONSTR SURG, V52, P111, DOI 10.1097/00006534-197308000-00001
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   Nanchalal J, 2009, STANDARDS MANAGEMENT
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   Yazar S, 2006, PLAST RECONSTR SURG, V117, P2468, DOI 10.1097/01.prs.0000224304.56885.c2
NR 12
TC 3
Z9 6
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-7043
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD JAN
PY 2011
VL 66
IS 1
BP 3
EP 5
DI 10.1097/SAP.0b013e318208f210
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 697GZ
UT WOS:000285502600002
PM 21173596
DA 2026-07-24
ER

PT J
AU Zizzo, M
   Morini, A
   Parini, D
   Bonelli, C
   Fabozzi, M
AF Zizzo, Maurizio
   Morini, Andrea
   Parini, Dario
   Bonelli, Candida
   Fabozzi, Massimiliano
TI An update on "The use of negative pressure wound therapy following stoma
   reversal: a systematic review and meta-analysis of randomized controlled
   trials" by Drumm et al
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Letter
C1 [Zizzo, Maurizio; Morini, Andrea; Bonelli, Candida; Fabozzi, Massimiliano] Azienda Un Sanit Locale IRCCS Reggio Emilia, Surg Oncol Unit, Via Giovanni Amendola,2, I-42122 Reggio Emilia, Italy.
   [Parini, Dario] Osped Santa Maria Misericordia Rovigo, Unit Gen Surg, Viale Tre Martiri,140, I-45100 Rovigo, Italy.
RP Zizzo, M (通讯作者)，Azienda Un Sanit Locale IRCCS Reggio Emilia, Surg Oncol Unit, Via Giovanni Amendola,2, I-42122 Reggio Emilia, Italy.
EM zizzomaurizio@gmail.com
RI Fabozzi, Massimiliano/AAE-6037-2022; Parini, Dario/ABC-5476-2020; Zizzo,
   Maurizio/AAE-2724-2020; Morini, Andrea/M-1579-2019
OI Zizzo, Maurizio/0000-0001-9841-7856; Morini, Andrea/0000-0001-9140-0488
CR Borejsza-Wysocki M, 2021, VIDEOSURGERY MINIINV, V16, P686, DOI 10.5114/wiitm.2021.106426
   Carrano FM, 2021, BJS OPEN, V5, DOI 10.1093/bjsopen/zrab116
   Drumm C, 2025, INT J COLORECTAL DIS, V40, DOI 10.1007/s00384-025-04865-2
   Hajibandeh S, 2024, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD014763.pub2
   Harris IM, 2024, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD013530.pub2
   Higgins J., 2011, CHAPTER 8 ASSESSING
   Kang SI, 2023, ANN SURG TREAT RES, V105, P126, DOI 10.4174/astr.2023.105.3.126
   Kojima K, 2021, BMC SURG, V21, DOI 10.1186/s12893-021-01446-2
   Nickolls BJ, 2024, BMJ OPEN, V14, DOI 10.1136/bmjopen-2023-075601
   Tiang T, 2024, ANZ J SURG, V94, P1627, DOI 10.1111/ans.18941
   Uchino M, 2016, DIGEST SURG, V33, P449, DOI 10.1159/000446550
   Wan X, 2014, BMC MED RES METHODOL, V14, DOI 10.1186/1471-2288-14-135
   Wierdak M, 2021, TECH COLOPROCTOL, V25, P185, DOI 10.1007/s10151-020-02372-w
NR 13
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0179-1958
EI 1432-1262
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD JUL 3
PY 2025
VL 40
IS 1
AR 151
DI 10.1007/s00384-025-04947-1
PG 3
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 4OS6L
UT WOS:001523051600001
PM 40608074
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Adkesson, MJ
   Travis, EK
   Weber, MA
   Kirby, JP
   Junge, RE
AF Adkesson, Michael J.
   Travis, Erika K.
   Weber, Martha A.
   Kirby, John P.
   Junge, Randall E.
TI Vacuum-assisted closure for treatment of a deep shell abscess and
   osteomyelitis in a tortoise
SO JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION
LA English
DT Article
ID PRESSURE WOUND THERAPY; BLOOD-FLOW; MANAGEMENT; EXPERIENCE
AB Case Description-A female Aldabra tortoise (Geochelone gigantea) was evaluated because of focal necrosis of the carapace.
   Clinical Findings-Debridement revealed a 14.5 X 11.5-cm area of shell necrosis, deep abscess formation, and osteomyelitis involving bacterial (Klebsiella pneumoniae, Staphylococcus aureus, and Pseudomonas spp) and fungal pathogens.
   Treatment and Outcome-Following extensive debridement, vacuum-assisted closure incorporating silver-impregnated bandaging materials was used. The wound was considered healed after 55 days, at which time a layer of epidermal tissue with progressing keratinization was present, with smooth underlying ossification. Keratinization with normal pigmentation continued over the next 67 days.
   Clinical Relevance-Findings suggested that vacuum-assisted closure with silver-impregnated bandaging materials may provide advantages over traditional methods in the treatment of shell lesions in chelonians, including faster wound healing, improved cosmetic appearance of the healed wound, superior control of microbial contamination, and lower overall treatment costs.
C1 Utahs Hogle Zoo, Salt Lake City, UT 84108 USA.
   Univ Missouri, Coll Vet Med, Dept Vet Med & Surg, Columbia, MO 65211 USA.
   Washington Univ, Sch Med, St Louis, MO 63110 USA.
C3 University of Missouri System; University of Missouri Columbia;
   Washington University (WUSTL)
RP Adkesson, MJ (通讯作者)，Utahs Hogle Zoo, 2600 E Sunnyside Ave, Salt Lake City, UT 84108 USA.
OI Adkesson, Michael/0000-0002-8766-5296
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Barten S L., 2006, Reptile Medicine and Surgery, V2nd, P893
   BENAMOTZ R, 2007, IN PRESS VET SURG
   Boyer TH., 2006, Reptile Medicine and Surgery, P696
   Bui TD, 2006, AM J SURG, V192, P235, DOI 10.1016/j.amjsurg.2006.01.013
   Caniano DA, 2005, J PEDIATR SURG, V40, P128, DOI 10.1016/j.jpedsurg.2004.09.016
   CLAYTON L, 2003, P ASS REP AMPH VET, P103
   Coke Rob L., 2006, Journal of Herpetological Medicine and Surgery, V16, P102
   Gemeinhardt KD, 2005, EQUINE VET EDUC, V17, P27, DOI 10.1111/j.2042-3292.2005.tb00331.x
   Heller L, 2006, AM J SURG, V191, P165, DOI 10.1016/j.amjsurg.2005.09.003
   Kirby JP, 2002, J TRAUMA, V53, P117, DOI 10.1097/00005373-200207000-00024
   Lafortune M, 2002, P AM ASS ZOO VET, P38
   Lafortune Maud, 2005, Journal of Herpetological Medicine and Surgery, V15, P4
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   LANZ OI, 2007, P N AM VET C, P1419
   McArthur Stuart, 2004, P403, DOI 10.1002/9780470698877.ch15
   McArthur Stuart, 2004, P35, DOI 10.1002/9780470698877.ch3
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   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   O'Malley B., 2005, CLIN ANATOMY PHYSL E
   Paul Julia Claire, 2005, Plast Surg Nurs, V25, P61
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Sibbald G, 2006, ADV SKIN WOUND CARE, V19, P447
   Tian J, 2007, CHEMMEDCHEM, V2, P129, DOI 10.1002/cmdc.200600171
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   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
NR 31
TC 31
Z9 41
U1 0
U2 17
PU AMER VETERINARY MEDICAL ASSOC
PI SCHAUMBURG
PA 1931 N MEACHAM RD SUITE 100, SCHAUMBURG, IL 60173-4360 USA
SN 0003-1488
J9 JAVMA-J AM VET MED A
JI JAVMA-J. Am. Vet. Med. Assoc.
PD OCT 15
PY 2007
VL 231
IS 8
BP 1249
EP 1254
DI 10.2460/javma.231.8.1249
PG 6
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA 221RJ
UT WOS:000250244700027
PM 17937557
DA 2026-07-24
ER

PT J
AU Ning, T
   Guo, HH
   Song, QW
   Mei, SW
   Wang, H
   Yu, HY
AF Ning, Tao
   Guo, Huihui
   Song, Qiwei
   Mei, Siwei
   Wang, Hao
   Yu, Haiyang
TI A Modified Negative Pressure Wound Therapy Reduces the Occurrence of
   Tension Blisters Around Negative Pressure Dressings
SO ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE
AB Background center dot To date, there is no effective solution for preventing the formation of blisters around negative-pressure wound dressings. In this study, we aim to address this problem and identify techniques to improve the negative-pressure drainage technique.
   Methods center dot A total of 129 patients from 2021.11 to 2022.11 who were previously treated in Fuyang People's Hospital were included in this retrospective analysis. All patients had negative-pressure drainage dressings applied to their wounds after undergoing thorough wound debridement. The patients were divided into the following groups: a traditional treatment group and a modified treatment group. The traditional treatment group comprised 60 patients who received negative-pressure wound therapy (NPWT) and a modified treatment group comprised 69 patients who received NPWT plus Vaseline gauze. The dressing coverage area, wound location, incidence of blisters around the dressing 3 days after NPWT, wound infection rate, and length of hospitalization were recorded. The incidence of blisters, wound infection rate, and wound location in the 2 groups were included as the categorical data and were compared using a chi-squared test. The dressing coverage area and length of hospitalization in the 2 groups were included as the quantitative data and were compared using an independent samples t test or with the Mann-Whitney test if the data were abnormally distributed.
   Results center dot The incidence rates of blisters in the traditional and modified treatment groups were 33.3% (20/60) and 13.0% (9/69), respectively, displaying a statistically significant difference (chi(2) = 7.581, P = .006). The infection rates of the 2 groups were 38.3% (23/60) and 20.3% (14/69), respectively, showing a statistically significant difference (chi(2) = 5.108; P = .024). The lengths of hospitalization in the 2 groups were 26.05 +/- 14.74 days and 18.17 +/- 7.54 days, respectively, showing a statistically significant difference (t = 3.892; P = .000). The dressing coverage areas were 150 cm(2) (88.75 cm(2), 600 cm(2)) and 150 cm(2) (124 cm(2), 600 cm(2)), respectively, showing no statistical difference (P = .759).
   Conclusion center dot Modified NPWT can effectively reduce the incidence of blisters, length of hospitalization, and infection rate of patients.
C1 [Ning, Tao; Guo, Huihui; Song, Qiwei; Mei, Siwei; Wang, Hao; Yu, Haiyang] Fuyang Peoples Hosp, Dept Orthopaed Surg, Fuyang, Peoples R China.
RP Ning, T (通讯作者)，Fuyang Peoples Hosp, Dept Orthopaed Surg, Fuyang, Peoples R China.
EM doctorning87@163.com
RI Yu, Haiyang/JVO-2592-2024; guo, huihui/GYQ-8331-2022
FU Bengbu Medical College Project Fund [2020byzd347]; Clinical Science
   Foundation of Anhui Medical University [2022xkj225]; Fuyang city health
   commission project fund [FY2021-027]
FX This work was supported by the Bengbu Medical College Project Fund
   (NO.2020byzd347) Clinical Science Foundation of Anhui Medical University
   (NO.2022xkj225), and Fuyang city health commission project fund
   (NO.FY2021-027)
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NR 19
TC 0
Z9 0
U1 0
U2 0
PU InnoVision Professional Media
PI Eagan
PA 3470 Washington Drive Suite 102, Eagan, MN 55122, UNITED STATES
SN 1078-6791
J9 ALTERN THER HEALTH M
JI Altern. Ther. Health Med.
PD NOV-DEC
PY 2023
VL 29
IS 8
BP 540
EP 544
PG 5
WC Integrative & Complementary Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Integrative & Complementary Medicine
GA EG1E0
UT WOS:001137669200090
PM 37678851
DA 2026-07-24
ER

PT J
AU Clifford, S
   Kelsom, C
   Alicuben, ET
AF Clifford, Sarah
   Kelsom, Corey
   Alicuben, Evan T.
TI Endoscopic Management of Iatrogenic Perforations
SO THORACIC SURGERY CLINICS
LA English
DT Article
DE Esophageal perforation; Stent; Clip; Endoscopic vacuum therapy
ID VACUUM-ASSISTED CLOSURE; ESOPHAGEAL PERFORATIONS; MULTICENTER
   EXPERIENCE; THERAPY; STENT; DEVICE; LEAKS; DEFECTS; OPTIONS; REPAIR
C1 [Clifford, Sarah; Kelsom, Corey; Alicuben, Evan T.] Univ Pittsburgh, Med Ctr, Dept Cardiothorac Surg, Div Thorac Surg, Pittsburgh, PA USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); University
   of Pittsburgh
RP Alicuben, ET (通讯作者)，5200 Ctr Ave,Suite 715, Pittsburgh, PA 15232 USA.
EM alicubenet@upmc.edu
RI Alicuben, Evan/OAJ-8003-2025
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NR 46
TC 0
Z9 0
U1 0
U2 0
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1547-4127
EI 1558-5069
J9 THORAC SURG CLIN
JI Thorac. Surg. Clin.
PD NOV
PY 2024
VL 34
IS 4
BP 331
EP 339
DI 10.1016/j.thorsurg.2024.07.001
EA SEP 2024
PG 9
WC Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System; Surgery
GA H7F3E
UT WOS:001325056800001
PM 39332858
DA 2026-07-24
ER

PT J
AU Fleck, T
   Moidl, R
   Giovanoli, P
   Wolner, E
   Grabenwoger, M
AF Fleck, T
   Moidl, R
   Giovanoli, P
   Wolner, E
   Grabenwoger, M
TI Early treatment of sternal wound infections with vacuum assisted closure
   therapy reduces involvement of the mediastinum and further diminishes
   the need of plastic reconstructive surgery
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Country Congress on VAC Therapy for Outpatients as well as
   In-Hospital Patients
CY MAY 21-22, 2003
CL Mainz, GERMANY
ID BRIDGE
C1 AKH Wien, Abt Herz Thoraxchirurg, A-1090 Vienna, Austria.
   AKH Wien, Abt Plast Chirurg, A-1090 Vienna, Austria.
C3 University Hospital Vienna; University Hospital Vienna
RP Fleck, T (通讯作者)，AKH Wien, Abt Herz Thoraxchirurg, Leitstelle 20A,Wahringer Gurtel 18-20, A-1090 Vienna, Austria.
EM t9204604@hotmail.com
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NR 9
TC 6
Z9 7
U1 0
U2 1
PU JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
PI STUTTGART
PA RUEDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD MAY
PY 2004
VL 129
SU 1
BP S35
EP S37
DI 10.1055/s-2004-822615
PG 3
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 826GF
UT WOS:000221816600011
PM 15168281
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI In vitro and clinical experience of Cutimed Sorbact: the evidence
   base
SO JOURNAL OF WOUND CARE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; CELL-SURFACE HYDROPHOBICITY; PRESSURE WOUND
   THERAPY; STAPHYLOCOCCUS-AUREUS; INFECTIONS; STREPTOCOCCI; RESISTANCE;
   BIOFILMS
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NR 136
TC 5
Z9 7
U1 0
U2 3
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD MAY
PY 2015
VL 24
IS 5
SU 3
BP S6
EP S30
PG 25
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA CJ8PB
UT WOS:000355764200002
PM 26079060
DA 2026-07-24
ER

PT J
AU Topkara, A
   Ozkan, A
   Ozcan, RH
AF Topkara, Adem
   Ozkan, Adem
   Ozcan, Ramazan Hakan
TI The treatment of tissue defects related to the compartment syndrome
   occurring in the fibula osteocutaneous free flap donor area with vacuum
   assisted closure therapy
SO MICROSURGERY
LA English
DT Letter
ID RECONSTRUCTION; SITE
C1 [Topkara, Adem; Ozkan, Adem; Ozcan, Ramazan Hakan] Pamukkale Univ Hosp, Dept Plast & Reconstruct Surg, TR-20070 Pamukkale, Denizli, Turkey.
C3 Pamukkale University
RP Topkara, A (通讯作者)，Pamukkale Univ Hosp, Dept Plast & Reconstruct Surg, TR-20070 Pamukkale, Denizli, Turkey.
EM ademdr@mynet.com
CR Shindo M, 2000, ARCH OTOLARYNGOL, V126, P1467, DOI 10.1001/archotol.126.12.1467
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   Zhou M, 2013, MICROSURG, V33, P620, DOI 10.1002/micr.22178
NR 3
TC 0
Z9 1
U1 1
U2 4
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0738-1085
EI 1098-2752
J9 MICROSURG
JI Microsurgery
PD JUL
PY 2015
VL 35
IS 5
BP 417
EP 418
DI 10.1002/micr.22351
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CN1KV
UT WOS:000358179800015
PM 25382650
DA 2026-07-24
ER

PT J
AU Hiyama, A
   Sakai, D
   Hattori, N
   Watanabe, M
AF Hiyama, Akihiko
   Sakai, Daisuke
   Hattori, Nobuaki
   Watanabe, Masahiko
TI Risk stratification of surgical site infection in high-risk spine
   surgery under prophylactic ciNPWT
SO BMC MUSCULOSKELETAL DISORDERS
LA English
DT Article
DE Closed-incision negative pressure wound therapy; Surgical site
   infection; Spine surgery; High-risk patients; Risk stratification; PICO
   7
ID PRESSURE WOUND THERAPY; VACUUM-ASSISTED CLOSURE; LUMBAR FUSION;
   MANAGEMENT; DISEASE
AB Background This retrospective observational single-center cohort study evaluated real-world outcomes of prophylactic closed-incision negative pressure wound therapy (ciNPWT) in high-risk spine surgery patients and explored the distribution of surgical site infection (SSI) across cumulative risk burden (RiskN) strata within this selectively treated cohort. Methods We reviewed consecutive spine surgery patients who received prophylactic single-use PICO 7 (Smith & Nephew) ciNPWT immediately after wound closure between April 2023 and October 2025. High-risk status was defined according to Japanese reimbursable criteria. Cumulative risk burden was quantified as RiskN (1, 2, or >= 3). SSI was defined based on CDC criteria and reported with Wilson 95% confidence intervals (CIs). Results A total of 104 patients were analyzed (mean age 70.2 +/- 12.7 years; BMI 24.1 +/- 4.5 kg/m & sup2;). The mean RiskN was 1.50 +/- 0.78 (RiskN 1: 68 patients; RiskN 2: 22; RiskN 3-4: 14). The most frequent risk factor was hypoalbuminemia (57/104, 54.8%). Overall SSI occurred in 4 of 104 patients (3.8%; 95% CI, 1.5-9.5%). SSI rates were 2.9% (2/68) in RiskN 1, 0% (0/22) in RiskN 2, and 14.3% (2/14) in RiskN >= 3. Surgical procedures were mainly lumbar posterior (56/104, 53.8%) and thoracolumbar posterior (21/104, 20.2%); SSIs occurred after thoracolumbar posterior surgery (2/21), cervical posterior surgery (1/14), and lumbar posterior surgery (1/56). The most commonly used dressing size was 15 & times; 15 cm (51/104, 49.0%). Conclusions In this selectively treated, reimbursement-linked high-risk spine surgery cohort managed with prophylactic ciNPWT, SSI was uncommon overall but remained observed in patients with higher cumulative risk burden. RiskN was used to contextualize residual SSI risk within this pragmatically treated population. The observed SSI rate should be interpreted as a residual ("breakthrough") infection rate within a high-risk population. As a descriptive study without a control group, this study does not directly demonstrate the treatment effect of ciNPWT. Further comparative studies are needed to determine its incremental benefit, cost-effectiveness, and appropriate indications.
C1 [Hiyama, Akihiko; Sakai, Daisuke; Hattori, Nobuaki; Watanabe, Masahiko] Tokai Univ, Sch Med, Dept Orthopaed Surg, Surg Sci, 143 Shimokasuya, Isehara, Kanagawa 2591193, Japan.
C3 Tokai University
RP Hiyama, A (通讯作者)，Tokai Univ, Sch Med, Dept Orthopaed Surg, Surg Sci, 143 Shimokasuya, Isehara, Kanagawa 2591193, Japan.
EM a.hiyama@tokai.ac.jp
RI Sakai, Daisuke/X-9164-2019; Hiyama, Akihiko/AAW-7362-2021
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   Lambrechts MJ, 2022, WORLD NEUROSURG, V168, P258, DOI [10.1016/j.wneu.2022.09.048, 10.1016/J.WNEU.2022.09.048]
   Liu ZS, 2023, INT WOUND J, V20, P4193, DOI 10.1111/iwj.14317
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Oishi T, 2025, ACUTE MED SURG, V12, DOI 10.1002/ams2.70069
   Pappalardo G, 2024, EUR J ORTHOP SURG TR, V34, P2303, DOI 10.1007/s00590-024-03983-x
   Pesenti S, 2018, EUR SPINE J, V27, P2469, DOI 10.1007/s00586-018-5733-7
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   Yeramaneni S, 2016, CURR REV MUSCULOSKE, V9, P327, DOI 10.1007/s12178-016-9352-9
   Zhou JM, 2020, SPINE, V45, P208, DOI 10.1097/BRS.0000000000003218
NR 24
TC 0
Z9 0
U1 0
U2 0
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2474
J9 BMC MUSCULOSKEL DIS
JI BMC Musculoskelet. Disord.
PD APR 11
PY 2026
VL 27
IS 1
AR 438
DI 10.1186/s12891-026-09826-6
EA APR 2026
PG 10
WC Orthopedics; Rheumatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Rheumatology
GA II9NC
UT WOS:001772787300004
PM 41965669
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Alemdar, A
   Egin, S
AF Alemdar, Ali
   Egin, Seracettin
TI Improvement of Three Duodenal Re-leaks: Two-way Vacuum-assisted Closure
SO JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
LA English
DT Article
DE Open abdomen; Vacuum-assisted closure; Severe peritonitis; Duodenal leak
AB We share our experience of a two-way vacuum-assisted closure (VAC) technique that allows patients to heal when generalised peritonitis develops because of a recurrent duodenal leak. Two patients underwent omentoplasty for duodenal ulcer perforation and one patient underwent antrectomy, gastrojejunostomy, and tube duodenostomy. Two-way VAC was performed by taking an abdominal fluid culture and washing the abdomen with 6-12 litres of warm saline. Two-way VAC exchange procedures were continued every 3 days and total parenteral nutrition was administered until cessation of the duodenal re-leak. The two-way VAC application was terminated when improvement in the re-leak was macroscopically detected. The subcutaneous layer was dissected from the anterior abdominal wall fascial layer, and the abdominal skin was closed without tension. The patients were subsequently discharged. Controlling the primary source is often difficult when treating duodenal re-leaks, and two-way VAC can localise the source of the peritonitis and remove toxic peritoneal material.
C1 [Alemdar, Ali; Egin, Seracettin] Univ Hlth Sci, Okmeydani Educ & Res Hosp, Dept Surg, Istanbul, Turkey.
C3 Istanbul Okmeydani Training & Research Hospital; University of Health
   Sciences Turkey
RP Egin, S (通讯作者)，Univ Hlth Sci, Okmeydani Educ & Res Hosp, Dept Surg, Istanbul, Turkey.
EM seracettin_egin@hotmail.com
RI Alemdar, Ali/HKV-6078-2023; Eğin, Seracettin/GQZ-0908-2022
CR Chalya PL, 2011, WORLD J EMERG SURG, V6, DOI 10.1186/1749-7922-6-31
   Coccolini F, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0167-4
   Maghsoudi H, 2011, SAUDI J GASTROENTERO, V17, P124, DOI 10.4103/1319-3767.77243
   Sanjanwala S, 2016, International Surgery Journal, P1314, DOI [10.18203/2349-2902.isj20162230, DOI 10.18203/2349-2902.isj20162230, 10.18203/2349-2902.isj20162230, DOI 10.18203/2349-2902.ISJ20162230]
   Sartelli M, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0032-7
NR 5
TC 0
Z9 0
U1 0
U2 0
PU COLL PHYSICIANS & SURGEONS PAKISTAN
PI KARACHI
PA SEVENTH CENTRAL ST, DEFENCE HOUSING AUTHORITY, KARACHI, 75500, PAKISTAN
SN 1022-386X
EI 1681-7168
J9 JCPSP-J COLL PHYSICI
JI JCPSP-J. Coll. Physicians Surg.
PD APR
PY 2022
VL 32
SU S
BP 15
EP 17
DI 10.29271/jcpsp.2022.JCPSPCR.CR15
PG 3
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA K8OP5
UT WOS:001018979100006
DA 2026-07-24
ER

PT J
AU Perry, TL
   Kranker, LM
   Mobley, EE
   Curry, EE
   Johnson, RM
AF Perry, Travis L.
   Kranker, Lindsay M.
   Mobley, Erin E.
   Curry, Eileen E.
   Johnson, R. Michael
TI Outcomes in Fournier's Gangrene Using Skin and Soft Tissue Sparing Flap
   Preservation Surgery for Wound Closure: An Alternative Approach to Wide
   Radical Debridement
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE Fournier's gangrene; necrotizing fasciitis; necrotizing soft tissue
   infection; complete necrosectomy; negative pressure wound therapy;
   centrifugal and vertical infection transmission; surgical; infection
ID VACUUM-ASSISTED CLOSURE; NECROTIZING FASCIITIS; SEVERITY INDEX;
   INFECTIONS; MANAGEMENT; PREDICTION; VALIDATION; EXPERIENCE; MORTALITY;
   THERAPY
AB Introduction. Fournier's gangrene (FG) remains a forbidding necrotizing soft tissue infection (NSTI) that necessitates early recognition, prompt surgical excision, and goal-directed antibiotic therapy. Traditionally, surgical management has included wide radical excision for sepsis control, but this management often leaves large, morbid wounds that require complex wound coverage, prolonged hospitalizations, and/or delayed healing. Objective. The purpose of this case series is to report the outcomes of FG using a surrogate approach of concurrent debridement of spared skin and soft tissue, negative pressure wound therapy (NPWT), and serial delayed primary closure (DPC). Materials and Methods. A retrospective review of 17 consecutive patients with FG treated with concurrent skin and soft tissue sparing surgery, NPWT, and serial DPC at Miami Valley Hospital Regional Adult Burn and Wound Center (Dayton, OH) between 2008 and 2018 was conducted. Patients were included if the following were noted: clinical suspicion of FG based on genital and perinea! cellulitis, fever, leukocytosis, and confirmation of tissue necrosis upon surgical exploration. Patients not treated with skin sparing surgical debridement or wounds with an inability to maintain a NPWT dressing seal were excluded. Results. The mean number of total surgeries including simultaneous debridement and reconstruction was 5.5. The average intensive care unit and hospital length of stay was 3.2 and 18.9 days, respectively. The average number of days from initial consult to wound closure was 24.3. The need for colostomy and skin grafts were nearly eliminated with this surrogate approach. Using this reproducible technique, DPC was achieved in 100% of patients. Only 11.8% (2/17) required split-thickness skin grafting as part of wound closure. The majority (9/17; 52.9%) were partially managed as an outpatient during wound closure. During staged DPC, the mean number of outpatient management days was 16.0. There were no mortalities in this series of patients. Conclusions. To the best of the authors' knowledge, this is the largest case series reported in the literature using skin and soft tissue sparing surgery for wound closure of a FG NSTI.
C1 [Perry, Travis L.; Mobley, Erin E.] Miami Valley Hosp Reg Adult Burn & Wound Ctr, Dayton, OH USA.
   [Perry, Travis L.; Kranker, Lindsay M.] Wright State Univ, Boonshoft Sch Med, Dept Surg, Dayton, OH 45409 USA.
   [Curry, Eileen E.; Johnson, R. Michael] Wright State Univ, Boonshoft Sch Med, Div Plast Surg, Dayton, OH 45409 USA.
C3 University System of Ohio; Wright State University Dayton; University
   System of Ohio; Wright State University Dayton
RP Perry, TL (通讯作者)，Wright State Univ, Miami Valley Hosp, Boonshoft Sch Med, Dept Surg, One Wyoming St,Suite 3271, Dayton, OH 45409 USA.
EM tlperry@premierhealth.com
RI Kranker, Lindsay M/AAZ-7139-2020
OI Kranker, Lindsay M/0000-0002-0372-929X
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   Palvolgyi R, 2014, AM SURGEON, V80, P926
   Perry TL, 2010, WOUNDS, V22, P146
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   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
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   Tahmaz L, 2006, INT J UROL, V13, P960, DOI 10.1111/j.1442-2042.2006.01448.x
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NR 38
TC 18
Z9 20
U1 0
U2 1
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD OCT
PY 2018
VL 30
IS 10
BP 290
EP +
PG 16
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA IV1TW
UT WOS:000484062600005
PM 30299266
DA 2026-07-24
ER

PT J
AU Pérez-Acevedo, G
   Torra-Bou, JE
   Peiró-García, A
   Vilalta-Vidal, I
   Urrea-Ayala, M
   Bosch-Alcaraz, A
   Blanco-Blanco, J
AF Perez-Acevedo, Gemma
   Torra-Bou, Joan Enric
   Peiro-Garcia, Alejandro
   Vilalta-Vidal, Inmaculada
   Urrea-Ayala, Mireia
   Bosch-Alcaraz, Alejandro
   Blanco-Blanco, Joan
TI Incisional negative pressure wound therapy for the prevention of
   surgical site complications in paediatric patients with non-idiopathic
   scoliosis: A randomized clinical trial (vol 21, e70034, 2024)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Correction
RI Blanco-Blanco, Joan/E-2813-2012; Bosch Alcaraz, Alejandro/KDO-0418-2024
CR Pérez-Acevedo G, 2024, INT WOUND J, V21, DOI 10.1111/iwj.70034
NR 1
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2024
VL 21
IS 10
AR e70067
DI 10.1111/iwj.70067
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA DD3ZT
UT WOS:001680763000001
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Zhao, JC
   Xian, CJ
   Kai, S
   Yu, JA
AF Zhao Jing-Chun
   Xian Chun-Jing
   Kai Shi
   Yu Jia-Ao
TI Severe Multiple Necrotizing Fasciitis Complicated by Abdominal
   Compartment Syndrome in an Infant
SO IRANIAN JOURNAL OF PEDIATRICS
LA English
DT Letter
DE Necrotizing Fasciitis; Abdominal Compartment Syndrome; Negative-Pressure
   Wound Therapy; Infant
ID INTRAABDOMINAL HYPERTENSION; INTERNATIONAL-CONFERENCE; EXPERTS
C1 [Zhao Jing-Chun; Xian Chun-Jing; Kai Shi; Yu Jia-Ao] Jilin Univ, Hosp 1, Burns & Plast Reconstruct Unit, Changchun 130031, Jilin Province, Peoples R China.
C3 Jilin University
RP Kai, S (通讯作者)，Jilin Univ, Hosp 1, Burns & Plast Reconstruct Unit, 3302 Jilin Rd, Changchun 130031, Jilin Province, Peoples R China.
EM bu_dong007@163.com
CR Abbo O, 2010, PEDIATR BLOOD CANCER, V55, P213, DOI 10.1002/pbc.22502
   Aydin U, 2010, J PLAST RECONSTR AES, V63, pE277, DOI 10.1016/j.bjps.2009.05.049
   Baharestani MM, 2007, OSTOMY WOUND MANAG, V53, P34
   Cheatham ML, 2007, INTENS CARE MED, V33, P951, DOI 10.1007/s00134-007-0592-4
   Malbrain MLNG, 2006, INTENS CARE MED, V32, P1722, DOI 10.1007/s00134-006-0349-5
   Peker E, 2010, J DERMATOL, V37, P671, DOI 10.1111/j.1346-8138.2010.00840.x
NR 6
TC 2
Z9 2
U1 1
U2 1
PU IRANIAN SCIENTIFIC SOCIETY MEDICAL ENTOMOLOGY
PI TEHRAN
PA SCHOOL PUBLIC HEALTH & INST HEALTH RESEARCH, TEHRAN UNIV MEDICAL
   SCIENCES, P O BOX  6446-14155, TEHRAN, 00000, IRAN
SN 2008-2142
EI 2008-2150
J9 IRAN J PEDIATR
JI Iran. J. Pediatr.
PD OCT
PY 2013
VL 23
IS 5
BP 601
EP 603
PG 3
WC Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics
GA 242LZ
UT WOS:000326244800020
PM 24800025
DA 2026-07-24
ER

PT J
AU Campos, D
   Perez, V
   Merkel, M
   Santini, MP
AF Campos, D.
   Perez, V
   Merkel, M.
   Palka Santini, M.
TI POTENTIAL BUDGET IMPACT OF NEGATIVE PRESSURE WOUND THERAPY (NPWT) VERSUS
   CONVENTIONAL WOUND TREATMENT IN DIABETIC FOOT ULCERS (DFU), SURGICAL AND
   TRAUMA FOR SELECTED COUNTRIES IN LATIN AMERICA
SO VALUE IN HEALTH
LA English
DT Meeting Abstract
C1 [Campos, D.] 3M Hlth Care, Pavas, Costa Rica.
   [Perez, V] 3M Argentina SACIFIA, Escobar, Argentina.
   [Merkel, M.; Palka Santini, M.] 3M Deutschland GmbH, Neuss, NW, Germany.
C3 3M
RI Merkel, Madeline/JYP-5766-2024
NR 0
TC 1
Z9 1
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1098-3015
EI 1524-4733
J9 VALUE HEALTH
JI Value Health
PD DEC
PY 2022
VL 25
IS 12
SU S
MA EE576
BP S169
EP S169
PG 1
WC Economics; Health Care Sciences & Services; Health Policy & Services
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Business & Economics; Health Care Sciences & Services
GA 6Z2FF
UT WOS:000897594901174
DA 2026-07-24
ER

PT J
AU Borsuk, DJ
   Jarzabek, AJ
   Marecik, SJ
   Park, JJ
   Gantt, G
   Kochar, K
AF Borsuk, D. J.
   Jarzabek, A. J.
   Marecik, S. J.
   Park, J. J.
   Gantt, G.
   Kochar, K.
TI PRIMARY LINEAR CLOSURE (PLC) WITH INCISIONAL NEGATIVE PRESSURE WOUND
   THERAPY (INPWT) VS. PURSE-STRING APPROXIMATION (PSA) FOR WOUND CLOSURE
   AFTER ILEOSTOMY REVERSAL: PRELIMINARY RESULTS FROM A RCT.
SO DISEASES OF THE COLON & RECTUM
LA English
DT Meeting Abstract
CT Annual Scientific Meeting of the
   American-Society-of-Colon-and-Rectal-Surgeons
CY MAR 04-MAY 04, 2022
CL Tampa, FL
SP Amer Soc Colon & Rectal Surg
NR 0
TC 1
Z9 1
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD MAY
PY 2022
VL 65
IS 5
MA S28
BP 16
EP 16
PG 1
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Gastroenterology & Hepatology; Surgery
GA 0I5JN
UT WOS:000779456900071
DA 2026-07-24
ER

PT J
AU Liu, T
   Yang, F
   Li, ZF
   Yi, CL
   Bai, XJ
AF Liu, Tao
   Yang, Fan
   Li, Zhanfei
   Yi, Chengla
   Bai, Xiangjun
TI A Prospective Pilot Study to Evaluate Wound Outcomes and Levels of Serum
   C-reactive Protein and Interleukin-6 in the Wound Fluid of Patients with
   Trauma-related Chronic Wounds
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE trauma; chronic wound; C-reactive protein; interleukin-6; negative
   pressure wound therapy
ID VACUUM-ASSISTED CLOSURE; NEGATIVE-PRESSURE THERAPY; GROWTH-FACTOR;
   INFECTION; CARE; MARKERS
AB If surgical closure of chronic wounds is an option, choosing an appropriate time to definitely close these wounds remains a challenge. Although the underlying mechanisms of nonhealing are not completely understood, serum C-reactive protein (CRP) and interleukin-6 (IL-6) in wound fluid have been found to be markers of the systemic and local inflammation state of chronic wounds. The purpose of this prospective, descriptive pilot study was to evaluate the effect of debridement, systemic antibiotics, and negative pressure wound therapy (NPWT) on the outcomes of trauma-related chronic wounds and changes in local inflammation responses, measured using CRP and IL-6 levels as indicators of cytokine regulation. Between June 2012 and May 2013, 20 consecutive patients (14 men, six women, mean age 40 [range 17-561 years) with various trauma-related, nonhealing chronic wounds were enrolled in the study after failing to heal for an average of 8.5 (range 6-16) weeks using a protocol of regular debridement and gauze dressings. Before the start of the study, wounds were cultured, and laboratory values for white blood cell count (WBC), neutrophils, and levels of serum CRP and IL-6 in the wound fluid obtained. Wounds were surgically debrided and NPWT (continuous at 125 mm Hg) applied. All patients were prescribed systemic antibiotics, and mean time interval between NPWT dressing changes was 5 (range 3-7) days. During an average mean NPWT treatment time of 13 (range 5-20) days, CRP and IL-6 concentrations decreased from 66.4 mg/L to 10.4 mg/L and 44.1 pg/mL to 8.6 pg/mL, respectively (P <0.001). The presence/absence of bacteria, WBC, and neutrophil counts did not change. No complications were noted, and all wounds were successfully closed using various surgical procedures. In this study, clinical wound improvement and a significant decrease in wound fluid CRP and IL-6 levels were observed. Studies with a larger sample size and a more robust study design may help elucidate the relationship between inflammatory molecules, infection, and healing outcomes.
C1 [Liu, Tao; Yang, Fan; Li, Zhanfei; Yi, Chengla; Bai, Xiangjun] Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Traumat Surg, Wuhan 430074, Peoples R China.
C3 Huazhong University of Science & Technology
RP Bai, XJ (通讯作者)，Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Hangkong Rd 1095, Wuhan 430074, Peoples R China.
EM baixiangjun@hotmail.com
RI Li, Zhanfei/JQW-2611-2023; Liu, Tao/OZE-7740-2025
OI Bai, Xiangjun/0009-0003-4847-2285; Liu, Tao/0009-0009-7392-9260
FU Ministry of Health Industry Sector Funds [201002014]; National 12th
   Five-support program - Research and Integrate New Technology
   Demonstration of Trauma [2012BA111B00]; Hubei Science and Technology Key
   Project [2013CFA075]; Hubei Province's Outstanding Medical Academic
   Leader Program; National Nature Science Foundation of China [81271348]
FX Dr. Bai's efforts were supported by the Ministry of Health Industry
   Sector Funds (Item Number. 201002014), the National 12th Five-support
   program - Research and Integrate New Technology Demonstration of Trauma
   (Item Number. 2012BA111B00), Hubei Science and Technology Key Project
   (Item Number. 2013CFA075), and Hubei Province's Outstanding Medical
   Academic Leader Program. Dr. Yi received support from the National
   Nature Science Foundation of China (Grant No. 81271348).
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NR 37
TC 21
Z9 24
U1 0
U2 10
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD JUN
PY 2014
VL 60
IS 6
BP 30
EP 37
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AK0FU
UT WOS:000338089100006
PM 24905355
DA 2026-07-24
ER

PT J
AU Adam, S
   Sama, HD
   Chossegros, C
   Bouassalo, MK
   Akpoto, MY
   Kpemissi, E
AF Adam, S.
   Sama, H. D.
   Chossegros, C.
   Bouassalo, M. K.
   Akpoto, M. Y.
   Kpemissi, E.
TI Improvised Vacuum-Assisted Closure for severe neck infection in poorly
   equipped conditions
SO JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY
LA English
DT Editorial Material
DE Neck; Infection; Dental decay; Drainage; Vacuum-Assisted Closure
AB Introduction: Dental infections are common and are mainly due to dental caries. When left untreated, these infections can lead to severe life-threatening sepsis.
   Case report: The authors reported a case of a severe odontogenic deep neck space infection in a 54-yearold male. The patient was a heavy smoker with incidentally discovered diabetes. He was successfully treated by surgical drainage combined with an improvised Vacuum-Assisted Closure (VAC) system. The results of surgical drainage followed by insertion of an improvised VAC system were spectacular. The abscess resolved in response to dual-agent antibiotic therapy on day 17 and blood glucose control was achieved with insulin. Full-thickness skin graft was performed to repair the necrotic zone of the neck.
   Discussion: The use of VAC can be a valuable alternative to conventional dressings and hyperbaric oxygen therapy in poorly equipped conditions. Public awareness campaigns remain the most effective form of prevention against these odontogenic infections. (C) 2017 Published by Elsevier Masson SAS.
C1 [Adam, S.; Kpemissi, E.] CHU Sylvanus Olympio, Serv ORL & Chirurg Cerv Maxillofaciale, 08 BP, Lome 8146, Togo.
   [Sama, H. D.] CHU Sylvanus Olympio, Serv Anesthesie Reanimat, Lome, Togo.
   [Chossegros, C.] CHU Marseille, Hop Concept, Stomatol Chirurg Maxillofaciale & Orale, 147 Blvd Baille, F-13385 Marseille 5, France.
   [Adam, S.; Bouassalo, M. K.] CHU Sylvanus Olympio, Serv Odontostomatol & Chirurg Maxillofaciale, Lome, Togo.
   [Akpoto, M. Y.] CHU Sylvanus Olympio, Serv Chirurg Traumatol & Orthopedie, Lome, Togo.
C3 Aix-Marseille Universite; Assistance Publique-Hopitaux de Marseille
RP Adam, S (通讯作者)，Serv Odontostomatol & Chirurg Maxillofaciale, 08 BP, Tokoin Lome 8146, Togo.
EM saliou.adam1@yahoo.com
OI chossegros, cyrille/0000-0001-9140-2045; Sama, Hamza
   D/0000-0001-5365-8154
CR Ayoubi A., 2009, Med. Buccale Chir. Buccale, V15, P127, DOI DOI 10.1051/MBCB/2009011
   Dagain A, 2007, ENCY MED CHIR STOMAT
   Deroux E., 2001, REV MED BRUX, V22, P289
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   Oczenski W, 2004, J CARDIOTHOR VASC AN, V18, P336, DOI 10.1053/j.jvca.2004.03.016
   Odzili FAI, 2014, REV STOMATOL CHIR, V115, P349, DOI 10.1016/j.revsto.2014.10.010
   Pasquier P, 2012, J TRAUMA ACUTE CARE, V73, P1630, DOI 10.1097/TA.0b013e3182751bad
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Serradji Z, 2012, ANN FR OTO RHINO LAR, V129, pA132
   Thiery G, 2009, NOUV DERMATOL, V28, P64
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
NR 13
TC 2
Z9 4
U1 0
U2 4
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 2468-8509
EI 2468-7855
J9 J STOMATOL ORAL MAXI
JI J. Stomatol. Oral Maxillofac. Surg.
PD JUN
PY 2017
VL 118
IS 3
BP 178
EP 180
DI 10.1016/j.jormas.2017.03.008
PG 3
WC Dentistry, Oral Surgery & Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dentistry, Oral Surgery & Medicine
GA FW0MS
UT WOS:000424989800008
PM 28391076
DA 2026-07-24
ER

PT J
AU Mueller, KB
   D'Antuono, M
   Patel, N
   Pivazyan, G
   Aulisi, EF
   Evans, KK
   Nair, MN
AF Mueller, Kyle B.
   D'Antuono, Matthew
   Patel, Nirali
   Pivazyan, Gnel
   Aulisi, Edward F.
   Evans, Karen K.
   Nair, M. Nathan
TI In Reply: Effect of Incisional Negative Pressure Wound Therapy vs
   Standard Wound Dressing on the Development of Surgical Site Infection
   After Spinal Surgery: A Prospective Observational Study
SO NEUROSURGERY
LA English
DT Letter
C1 [Mueller, Kyle B.] Univ Penn, Dept Neurosurg, Philadelphia, PA 19104 USA.
   [Mueller, Kyle B.] Virtua Our Lady Lourdes Hosp, Penn Virtua Dept Neurosci, Camden, NJ 08103 USA.
   [D'Antuono, Matthew] Georgetown Univ, Sch Med, Washington, DC USA.
   [Patel, Nirali; Pivazyan, Gnel; Nair, M. Nathan] Georgetown Univ, Med Ctr, Dept Neurosurg, Washington, DC USA.
   [Aulisi, Edward F.] MedStar Washington Hosp Ctr, Dept Neurosurg, Washington, DC USA.
   [Evans, Karen K.] Georgetown Univ, Med Ctr, Dept Plast Surg, Washington, DC USA.
C3 University of Pennsylvania; Georgetown University; Georgetown
   University; MedStar Washington Hospital Center; Georgetown University
RP Mueller, KB (通讯作者)，Univ Penn, Dept Neurosurg, Philadelphia, PA 19104 USA.; Mueller, KB (通讯作者)，Virtua Our Lady Lourdes Hosp, Penn Virtua Dept Neurosci, Camden, NJ 08103 USA.
RI D'Antuono, Matthew/AAD-5725-2020; Mueller, Kyle/HSI-4288-2023; Pivayzan,
   Gnel/JJF-1220-2023
OI D'Antuono, Matthew/0000-0002-1837-7004; 
CR Cai YK, 2021, NEUROSURGERY, V89, pE341, DOI 10.1093/neuros/nyab350
   Flanders TM, 2020, PAIN MED, V21, P3283, DOI 10.1093/pm/pnaa233
   Mueller KB, 2021, WORLD NEUROSURG, V152, P233, DOI [10.1016/j.wneu.2021.06.049, 10.1016/J.WNeu.2021.06.049]
   Mueller KB, 2021, NEUROSURGERY, V88, pE445, DOI 10.1093/neuros/nyab040
NR 4
TC 0
Z9 2
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-396X
EI 1524-4040
J9 NEUROSURGERY
JI Neurosurgery
PD DEC
PY 2021
VL 89
IS 6
BP E343
EP E343
DI 10.1093/neuros/nyab351
EA SEP 2021
PG 1
WC Clinical Neurology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA XL8IC
UT WOS:000728383900008
PM 34498690
DA 2026-07-24
ER

PT J
AU Eskandarnejad, S
AF Eskandarnejad, Shahram
TI AN INITIATIVE FOR TREATMENT OF SINUS TRACT (ST) IN WOUNDS WITH DRESSINGS
   OTHER THAN POLYVINYL ALCOHOL (PVA) AND POLYURETHANE (PU) FOAMS UNDER
   NEGATIVE PRESSURE WOUND THERAPY (NPWT)
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Eskandarnejad, Shahram] Home Hlth, Santa Rosa, CA USA.
EM shahram.es@gmail.com
CR Gibson DJ, 2022, J WOUND OSTOMY CONT, V49, P51, DOI 10.1097/WON.0000000000000833
   Loh ML, 2020, INT WOUND J, V17, P1356, DOI 10.1111/iwj.13406
   Newton H, 2016, Wound Essentials, V11, P8
NR 3
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JUL-AUG
PY 2025
VL 52
IS 4S
SU 4
MA PI17
PG 93
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 5WF1Q
UT WOS:001545803300031
DA 2026-07-24
ER

PT J
AU Law, A
   Cyhaniuk, A
   Krebs, B
AF Law, Amy
   Cyhaniuk, Anissa
   Krebs, Blake
TI Comparison of Health Care Costs and Hospital Readmission Rates
   Associated With Negative Pressure Wound Therapies
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE negative pressure wound therapy; cost effective; comparative
   effectiveness; chronic wounds
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; RANDOMIZED-TRIAL;
   PREVALENCE; IMPACT
AB Objective. A retrospective national claims database analysis evaluated total and wound-related costs (eg, hospital readmission rates) for patients with chronic wounds treated with negative pressure wound therapy (NPWT), comparing NPWT-V (V.A.C. Therapy, KCI, an Acelity company, San Antonio, TX) and NPWT-O (other non-KCI models of NPWT, the brands of which were not known to the researchers). Methods. Patients with >= 1 NPWT claim from January 2009-June 2012 in outpatient settings in the United States were included, if they had continuous medical and pharmacy benefits for 12 months before the initial index date of their NPWT claim and at least 3 months post index. Mean total health care costs were assessed at 3 months and 12 months; wound-related hospital readmission rates were assessed at 3 months and 6 months. Cost differences between cohorts were analyzed by t test and readmission rates were analyzed by chi-square test. Results. At 3 months, the cohort of NPWT-V patients was significantly younger (59.2 vs 63.6 years, P < 0.01). The same patients were followed at 3, 6, and 12 months, although some fell out as time progressed. At the 3-month assessment, mean comorbidity scores did not differ between the NPWT-V group and the NPWT-O groups (3.38 vs 3.66). Total costs were lower for NPWT-V vs NPWT-O at 3 months ($35,498 vs $39,722, respectively; P = 0.08) and 12 months ($80,768 vs $111,212; P = 0.03). Significantly lower inpatient (P = 0.01), emergency room (P < 0.01), and home (P = 0.05) costs, despite higher (P = 0.04) NPWT costs, accounted for lower 12-month NPWT-V total costs. Wound-related readmission rates were significantly lower for NPWT-V at 3 months (5% vs 8%; P <= 0.01) and 6 months (6% vs 11%; P = 0.01). For all wound types, NPWT-O patients had a 17-fold higher rate of switching to alternate NPWT models compared with NPWT-V patients. Conclusion. In this retrospective analysis, NPWT-V patients had lower total costs, lower wound-related costs, and lower hospital readmission rates than NPWT-O patients at all time points assessed.
C1 [Law, Amy] Acelity Co, KCI, San Antonio, TX 78249 USA.
   [Cyhaniuk, Anissa; Krebs, Blake] Optum Life Sci, Eden Prairie, MN USA.
C3 Optum
RP Law, A (通讯作者)，Acelity Co, KCI, 12930 Interstate Highway 10 West, San Antonio, TX 78249 USA.
EM amy.law@acelity.com
FU Optum Life Sciences (Eden Prairie, MN)
FX The authors disclose that Amy Law is an employee of KCI, an Acelity
   Company (San Antonio, TX); Anissa Cyhaniuk and Blake Krebs, with Optum
   Life Sciences (Eden Prairie, MN), were paid consultants on this study.
   Claims data and analytics were provided by Optum Life Sciences.
CR [Anonymous], 3 C WORLD UN WOUND H
   [Anonymous], CONGR BUDG OFF PUB
   [Anonymous], 2009, NURS MANAGE
   [Anonymous], AG HEALTHC RES QUAL
   [Anonymous], PODIATRY TODAY
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   Baharestani MM, 2008, OSTOMY WOUND MANAG, V54, P48
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   Charlson ME, 2008, J CLIN EPIDEMIOL, V61, P1234, DOI 10.1016/j.jclinepi.2008.01.006
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   Fife CE, 2012, OSTOMY WOUND MANAG, V58, P20
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   Joseph E, 2000, WOUNDS, V12, P60
   Kaplan M, 2009, ADV SKIN WOUND CARE, V22, P128, DOI 10.1097/01.ASW.0000305451.71811.d5
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   Shearer A, 2003, DIABETES CARE, V26, P2305, DOI 10.2337/diacare.26.8.2305
   Suissa D, 2011, PLAST RECONSTR SURG, V128, p498E, DOI 10.1097/PRS.0b013e31822b675c
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   Wanner MB, 2003, SCAND J PLAST RECONS, V37, P28
   Word R, 2010, SURG CLIN N AM, V90, P1195, DOI 10.1016/j.suc.2010.08.008
NR 28
TC 6
Z9 6
U1 0
U2 12
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD MAR
PY 2015
VL 27
IS 3
BP 63
EP 72
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CD7UA
UT WOS:000351297600004
PM 25786078
DA 2026-07-24
ER

PT J
AU Albert, NM
   Rock, R
   Sammon, MA
   Bena, JF
   Morrison, SL
   Whitman, A
   Kato, I
   Landis-Erdman, JC
AF Albert, Nancy M.
   Rock, Ronald
   Sammon, Mary Ann
   Bena, James F.
   Morrison, Shannon L.
   Whitman, Angela
   Kato, Irene
   Landis-Erdman, Judith C.
TI Do Patient and Nurse Outcome Differences Exist Between 2 Negative
   Pressure Wound Therapy Systems?
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED-TRIAL; MANAGEMENT; ULCERS; COST
AB PURPOSE: We prospectively compared the effectiveness of foam- and gauze-based negative pressure wound therapy (NPWT) systems on wound healing, pain, cost, and hospital length of stay. We also compare ease of use and time in performing dressing changes reported by nurses.
   DESIGN: Randomized, controlled clinical trial comparing foam- and gauze-based NPWT systems.
   SUBJECTS AND SETTING: Eleven adult subjects with physician orders for NPWT participated in the study. Subjects were middle-aged, white, and male.
   METHODS: Six subjects were randomly allocated to foam- based and 5 to gauze-based NPWT systems. Wound healing rates and pain at the first dressing change were measured using a centimeter ruler and a visual analog scale, respectively. Wound care costs were tabulated from a checklist of supplies used and nurse perceptions were measured by responses to Likert-type surveys. Relationships between NPWT system and selected variables were measured using Wilcoxon rank sum tests.
   RESULTS: Median wound healing rates did not differ significantly between foam- based and gauze-based NPWT systems when measured in centimeters at first dressing change for length (10.6 vs 16.5, P = .58), width (2.7 vs 4.2, P = .41), depth (2.2 vs 2.5, P = .78), and tunneling and undermining (both 0 vs 0, P = .82 and.79, respectively). No differences were detected in pain rating at first dressing change (3.2 vs 2.4, P = .77), cost of wound care ($510.18 vs $333.54 P = .86), or hospital length of stay (26.33 vs 14.8 days; P = .58), respectively. There were no differences in nurses' experiences in ease of performing dressing changes and mean time to perform the first dressing change for foam- or gauze-based NPWT systems: 32.3 vs 38.8 minutes; P = .52, respectively.
   CONCLUSIONS: In a pilot study comparing the effectiveness of foam- and gauze-based NPWT systems, no statistically significant differences were found in patient wound healing, pain, length of stay, or cost of wound care. Nursing time and perceptions about the ease of preparing and completing dressing changes did not differ between systems. Additional research is needed to more definitively determine any differences in wound healing or nurse satisfaction using gauze-versus foam-based NPWT systems.
C1 [Albert, Nancy M.] Cleveland Clin, Nursing Inst, Cleveland, OH 44195 USA.
   [Sammon, Mary Ann; Landis-Erdman, Judith C.] Cleveland Clin, Wound Care Consult Team, Cleveland, OH 44195 USA.
   [Whitman, Angela] Cleveland Clin, Vasc Surg Stepdown Unit, Cleveland, OH 44195 USA.
   [Kato, Irene] Cleveland Clin, Colo Rectal Surg Unit, Cleveland, OH 44195 USA.
C3 Cleveland Clinic Foundation; Cleveland Clinic Foundation; Cleveland
   Clinic Foundation; Cleveland Clinic Foundation
RP Albert, NM (通讯作者)，Cleveland Clin, Nursing Inst, 9500 Euclid Ave,Mail Code J3-4, Cleveland, OH 44195 USA.
EM albertn@ccf.org
RI Albert, Nancy/ACQ-4895-2022
FU Smith & Nephew (St. Petersburg, Florida)
FX We thank Cheryl Patterson, PhD, MBA, RN, and Patricia Adler, PhD, RN,
   for their roles in study oversight and Laura Rinker, RN, CPN, for her
   role in coordination of patient enrollment. Smith & Nephew (St.
   Petersburg, Florida) provided partial funding for data collection and
   full funding of statistical analysis.
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NR 30
TC 14
Z9 14
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2012
VL 39
IS 3
BP 259
EP 266
DI 10.1097/WON.0b013e3182487a50
PG 8
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 940VJ
UT WOS:000303920900006
PM 22552107
DA 2026-07-24
ER

PT J
AU Peinemann, F
   McGauran, N
   Sauerland, S
   Lange, S
AF Peinemann, Frank
   McGauran, Natalie
   Sauerland, Stefan
   Lange, Stefan
TI Disagreement in primary study selection between systematic reviews on
   negative pressure wound therapy
SO BMC MEDICAL RESEARCH METHODOLOGY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; SUCTION DRAINAGE; RANDOMIZED-TRIAL; MANAGEMENT;
   QUALITY; INTERVENTIONS; STATEMENT; CAUTION
AB Background: Primary study selection between systematic reviews is inconsistent, and reviews on the same topic may reach different conclusions. Our main objective was to compare systematic reviews on negative pressure wound therapy ( NPWT) regarding their agreement in primary study selection.
   Methods: This retrospective analysis was conducted within the framework of a systematic review ( a full review and a subsequent rapid report) on NPWT prepared by the Institute for Quality and Efficiency in Health Care ( IQWiG). For the IQWiG review and rapid report, 4 bibliographic databases ( MEDLINE, EMBASE, The Cochrane Library, and CINAHL) were searched to identify systematic reviews and primary studies on NPWT versus conventional wound therapy in patients with acute or chronic wounds. All databases were searched from inception to December 2006. For the present analysis, reviews on NPWT were classified as eligible systematic reviews if multiple sources were systematically searched and the search strategy was documented. To ensure comparability between reviews, only reviews published in or after December 2004 and only studies published before June 2004 were considered. Eligible reviews were compared in respect of the methodology applied and the selection of primary studies.
   Results: A total of 5 systematic reviews ( including the IQWiG review) and 16 primary studies were analysed. The reviews included between 4 and 13 primary studies published before June 2004. Two reviews considered only randomised controlled trials ( RCTs). Three reviews considered both RCTs and non- RCTs. The overall agreement in study selection between reviews was 96% for RCTs ( 24 of 25 options) and 57% for non- RCTs ( 12 of 21 options). Due to considerable disagreement in the citation and selection of non- RCTs, we contacted the review authors for clarification ( this was not initially planned); all authors or institutions responded. According to published information and the additional information provided, most differences between reviews arose from variations in inclusion criteria or interauthor study classification, as well as from different reporting styles ( citation or non- citation) for excluded studies.
   Conclusion: The citation and selection of primary studies differ between systematic reviews on NPWT, particularly with regard to non- RCTs. Uniform methodological and reporting standards need to be applied to ensure comparability between reviews as well as the validity of their conclusions.
C1 [Peinemann, Frank; McGauran, Natalie; Lange, Stefan] Inst Qual & Efficiency Hlth Care IQWiG, D-51105 Cologne, Germany.
   [Sauerland, Stefan] Univ Witten Herdecke, Inst Res Operat Med, D-51109 Cologne, Germany.
C3 Witten Herdecke University
RP Peinemann, F (通讯作者)，Inst Qual & Efficiency Hlth Care IQWiG, Dillen Burger Str 27, D-51105 Cologne, Germany.
EM frank.peinemann@iqwig.de; n.mcgauran@iqwig.de;
   stefan.sauerland@ifomuni-wh.de; stefan.lange@iqwig.de
RI ; Peinemann, Frank/H-2800-2019
OI Sauerland, Stefan/0000-0003-1048-796X; Peinemann,
   Frank/0000-0002-4727-1313
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NR 70
TC 16
Z9 17
U1 0
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2288
J9 BMC MED RES METHODOL
JI BMC Med. Res. Methodol.
PD JUN 26
PY 2008
VL 8
AR 41
DI 10.1186/1471-2288-8-41
PG 16
WC Health Care Sciences & Services
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services
GA 335PM
UT WOS:000258302500001
PM 18582373
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Egin, S
AF Egin, Seracettin
TI Management of Leakage into the Abdomen due to the Involvement of Jejunum
   in the Incision Line
SO JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
LA English
DT Article
DE Open abdomen; Vacuum-assisted closure; Intraabdominal sepsis
ID ABDOMINAL SEPSIS
AB Here, we present the management of a patient, developing severe peritonitis due to laceration of the jejunum, involving sutures applied to facial layers after anterior resection for adenocarcinoma of the sigmoid colon. The patient, an 83-year woman, was operated by anterior resection, and relaparotomy was performed because the small bowel contents leaked from the incision. A compulsory stoma on the top of the incision was performed. Bilateral fasciocutaneous advancement flaps were carried out to treat the patient with severe intraabdominal sepsis via vacuum-assisted closure. The patient, with Apache-II score 12, open abdomen Bjorck score 2C, and Mannheim peritonitis index score 28, was monitored in the intensive care unit. Based on our experience, open abdomen management with vacuum-assisted closure might be successful for patients with intraabdominal sepsis because of uncontrollable primer sources. We propose that the technique defined for this patient is an innovative technique for primary source control of open abdomen patients.
C1 [Egin, Seracettin] Univ Hlth Sci, Okmeydani Educ & Res Hosp, Dept Surg, Istanbul, Turkey.
C3 Istanbul Okmeydani Training & Research Hospital; University of Health
   Sciences Turkey
RP Egin, S (通讯作者)，Univ Hlth Sci, Okmeydani Educ & Res Hosp, Dept Surg, Istanbul, Turkey.
EM seracettin_egin@hotmail.com
RI Eğin, Seracettin/GQZ-0908-2022
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NR 8
TC 0
Z9 0
U1 0
U2 1
PU COLL PHYSICIANS & SURGEONS PAKISTAN
PI KARACHI
PA SEVENTH CENTRAL ST, DEFENCE HOUSING AUTHORITY, KARACHI, 75500, PAKISTAN
SN 1022-386X
EI 1681-7168
J9 JCPSP-J COLL PHYSICI
JI JCPSP-J. Coll. Physicians Surg.
PD MAY
PY 2019
VL 29
IS 5
BP 476
EP 477
DI 10.29271/jcpsp.2019.05.476
PG 2
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA HV7MC
UT WOS:000466164100020
PM 31036123
OA gold
DA 2026-07-24
ER

PT J
AU Kim, Y
   Cui, CL
   Shafique, HS
   Weissler, EH
   Johnson, AP
   Coleman, DM
   Southerland, KW
AF Kim, Young
   Cui, Christina L.
   Shafique, Hana S.
   Weissler, E. Hope
   Johnson, Adam P.
   Coleman, Dawn M.
   Southerland, Kevin W.
TI Effectiveness of Negative Pressure Wound Therapy on Groin Surgical Site
   Infection After Lower Extremity Bypass for Chronic Limb-Threatening
   Ischemia
SO ANNALS OF VASCULAR SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; VASCULAR-SURGERY; REVASCULARIZATION;
   COMPLICATIONS; EPIDEMIOLOGY; PREDICTORS; REDUCTION; DISEASE; TRIAL;
   CINPT
AB Background: Surgical site infections (SSIs) are a common cause of patient morbidity, hospital readmission, and reoperation after lower extremity bypass (LEBs) surgery for chronic limbthreatening ischemia (CLTI). Recent studies on the use of incisional negative pressure wound therapy (NPWT) in LEB surgery have reported conflicting results. In this single-center study, we examined our experience on the impact of NPWT on groin SSI rates after LEB surgery.<br /> Methods: We retrospectively queried electronic medical records for all LEB operations performed for CLTI. Multivariate logistic regression analysis was used to identify risk factors associated with postoperative SSI. Using these risk factors, subset analysis was performed to determine whether NPWT was associated with reduced SSI in high-risk patients.<br /> Results: From 2018 to 2022, a total of 367 patients underwent LEB surgery for CLTI. Mean patient age was 66 years. Postoperative groin SSI was diagnosed in 22.9% (n - 84) of patients. Patients suffering SSI were more frequently morbidly obese (6.0% vs 1.8%, P - 0.03) and had higher rates of chronic obstructive pulmonary disease (35.7% vs 23.3%, P - 0.02). Other comorbidities and demographic data were similar between groups. NPWT was utilized in 19.6% (n - 72) of patients, with no baseline differences between SSI and no SSI cohorts (15.5% vs 20.9%, P - 0.28). On multivariate analysis, female sex (odds ratio [OR] 1.88, 95% confidence interval [CI] 1.06-3.35, P - 0.03), white race (OR 2.17, 95% CI 1.23-3.82, P - 0.007), morbid obesity (OR 3.67, 95% CI 0.93-14.4, P - 0.05), and active smoking (OR 4.07, 95% CI 1.20-13.8, P - 0.02) were independently associated with postoperative SSI. Subset analysis among patients at increased risk of SSI did not reveal any differences in wound infection with NPWT usage.<br /> Conclusions: In our experience, NPWT does not appear to be more effective than standard dressings in preventing groin SSI after LEB surgery for CLTI, even among populations at heightened risk for wound infection.
C1 [Kim, Young; Cui, Christina L.; Shafique, Hana S.; Weissler, E. Hope; Johnson, Adam P.; Coleman, Dawn M.; Southerland, Kevin W.] Duke Univ, Div Vasc & Endovasc Surg, Durham, NC USA.
C3 Duke University
RP Kim, Y (通讯作者)，Duke Univ, Med Ctr, Div Vasc & Endovasc Surg, 2301 Erwin Rd, Durham, NC 27708 USA.
EM y.kim@duke.edu
OI Johnson, Adam/0000-0002-3014-6372; Kim, Young/0000-0001-8763-8813;
   Coleman, Dawn/0000-0001-5622-7253
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NR 45
TC 3
Z9 3
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD FEB
PY 2025
VL 111
BP 143
EP 150
DI 10.1016/j.avsg.2024.10.020
EA DEC 2024
PG 8
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA R1B0P
UT WOS:001388881300001
PM 39581325
DA 2026-07-24
ER

PT J
AU Coulter, J
   O'Leary, M
   Hudson, A
   Murdoch, J
   Spitzer, M
AF Coulter, John
   O'Leary, Michael
   Hudson, Ashley
   Murdoch, Julie
   Spitzer, Mandy
TI A SERVICE EVALUATION DEMONSTRATING THE PROTOCOLIZATION OF A SINGLE-USE
   NEGATIVE PRESSURE WOUND THERAPY DEVICE FOR REDUCING SURGICAL SITE
   COMPLICATION RISK FOLLOWING GYNECOLOGY AND GYNECOLOGICAL ONCOLOGICAL
   SURGERY
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [O'Leary, Michael] Dept Gynaecol, Galway, Ireland.
EM coulter.j1@googlemail.com; drmoleary@gmail.com;
   Ashley.Hudson@smith-nephew.com; Julie.Murdoch@smith-nephew.com;
   amanda.spitzer@smith-nephew.com
CR Beecher SM, 2018, ONCOL RES TREAT, V41, P478, DOI 10.1159/000487510
   Deptula M, 2019, POSTEP DERM ALERGOL, V36, P139, DOI 10.5114/ada.2018.72585
   Nugent EK, 2011, Gynecol Oncol, V121, P272
   O'Donnell RL, 2019, BMJ OPEN, V9, DOI 10.1136/bmjopen-2018-024853
   Taylor JS, 2017, ANN SURG ONCOL, V24, P362, DOI 10.1245/s10434-016-5517-4
NR 5
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2024
VL 51
IS 3
SU S
MA R11
BP S69
EP S70
PG 2
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA C6T5F
UT WOS:001290677800147
DA 2026-07-24
ER

PT J
AU Tiensawang, T
AF Tiensawang, Thanuttha
TI MANAGEMENT OF A COLOCUTANEOUS FISTULA IN A LARGE ABDOMINAL WOUND WITH A
   COLLAPSIBLE SILICONE FISTULA ISOLATION DEVICE AND NEGATIVE PRESSURE
   WOUND THERAPY WITH INSTILLATION THERAPY (NPWT-i)
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Tiensawang, Thanuttha] Wound Ost Continence Nursing Serv, Los Angeles, CA USA.
EM ttiensawang@mednet.ucla.edu
CR Di Saverio S, 2016, LANGENBECK ARCH SURG, V401, P1, DOI 10.1007/s00423-015-1370-3
NR 1
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2017
VL 44
IS 3
SU S
MA PI59
BP S48
EP S48
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA EV4HE
UT WOS:000401718800116
DA 2026-07-24
ER

PT J
AU Barzilay, O
   Gefen, A
AF Barzilay, Ofek
   Gefen, Amit
TI Be there or be square: Should we adopt non-rectangular dressing shapes
   in single-use negative pressure wound therapy?
SO JOURNAL OF TISSUE VIABILITY
LA English
DT Article
DE Dressing design and shape optimization; Wound healing biomechanics;
   Computational finite element modeling and simulations; Mechanobiology in
   wound care; Skin and subdermal tissue stress concentrations
ID VACUUM-ASSISTED CLOSURE; TISSUE LOADS
AB Background: Single-use negative-pressure wound therapy (suNPWT) dressings for closed surgical incisions are predominantly rectangular, despite long-time evidence from biomechanics that sharp or small-radius corners generate localized stress concentrations in underlying tissues. Optimizing dressing geometry and stiffness distribution may reduce the peri-incisional stress concentrations and improve closure. Objectives: To determine how dressing shape and regional stiffness variations influence the peri-wound skin stresses and stress concentrations and the incision closure biomechanics under a negative pressure level of-125 mmHg. Methods: A validated three-dimensional finite element model of a sutured midline incision was developed. Five homogeneous dressing shapes (rectangular, circular, elliptical, stadium, and dome) of identical contact area and material properties were compared for reduction in peak lateral skin stresses (Delta S). The best-performing dressing shape underwent further testing in eight stiffness configurations (homogeneous, or with stiffer/softer peripheral regions in symmetric or axisymmetric patterns). The lateral displacement of the peri-wound skin was used as a measure for the closure work. A sensitivity analysis was conducted on chosen model variants for broader transferability and for exploring potential covariance between dressing shape and material properties. Results: Among the homogeneous dressing shapes, the circular dressing achieved the greatest stress reduction (Delta S = 2.9 %) versus the rectangular control (0.9 %). In the circular form, incorporating a stiffer peripheral symmetric ring around a softer core improved performance (Delta S = 3.2 %) while maintaining substantial lateral displacement (3.35 mm), achieving an optimal combination of stress relief with closure assistance. A fully stiff homogeneous dressing maximized the Delta S (6.5 %) but provided negligible closure support, whereas a fully soft dressing behaved conversely. The sensitivity analysis did not change these quantitative rankings across the studied model variants. Conclusions: Eliminating sharp or small-radius geometric discontinuities and tuning the regional stiffness can markedly attenuate peri-incisional stresses without compromising the contribution of the dressing to the closure work. Circular suNPWT dressings with a peripheral stiffer ring offer a biomechanically superior, manufacturable alternative to conventional rectangular designs, warranting further pre-clinical and clinical evaluations.
C1 [Barzilay, Ofek; Gefen, Amit] Tel Aviv Univ, Fac Engn, Sch Biomed Engn, Tel Aviv, Israel.
   [Gefen, Amit] Univ Ghent, Univ Ctr Nursing & Midwifery, Dept Publ Hlth & Primary Care, Skin Integr Res Grp SKINT, Ghent, Belgium.
   [Gefen, Amit] Hasselt Univ, Dept Math & Stat, Fac Sci, Hasselt, Belgium.
   [Gefen, Amit] Hasselt Univ, Data Sci Inst, Fac Sci, Hasselt, Belgium.
C3 Tel Aviv University; Ghent University; Ghent University Hospital;
   Hasselt University; Hasselt University
RP Gefen, A (通讯作者)，Tel Aviv Univ, Fac Engn, Herbert J Berman Chair Vasc Bioengn, Sch Biomed Engn,Biomed Engn, IL-69978 Tel Aviv, Israel.
EM gefen@tauex.tau.ac.il
RI Gefen, Amit/M-4720-2015
OI Gefen, Amit/0000-0002-0223-7218
FU Israeli Ministry of Innovation, Science and Technology: Breakthrough
   Research Program [1001702603]
FX This work was partially supported by the Israeli Ministry of Innovation,
   Science and Technology: Breakthrough Research Program Grant no.
   1001702603, awarded to Professor Amit Gefen in 2023.
CR Adie GC, United States patent, Patent No. [2015;9, 20159]
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NR 25
TC 1
Z9 1
U1 1
U2 2
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0965-206X
EI 1876-4746
J9 J TISSUE VIABILITY
JI J. Viab.
PD FEB
PY 2026
VL 35
IS 1
AR 100977
DI 10.1016/j.jtv.2025.100977
EA DEC 2025
PG 10
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA S8008
UT WOS:001636957400001
PM 41351949
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Todd, JR
   Zaman, K
   Bayat, A
AF Todd, J. R.
   Zaman, K.
   Bayat, A.
TI INNOVATIVE TREATMENT FOR EXTENSIVE SELF HARM SCARRING THROUGH
   SIMULTANEOUS USE OF A SINGLE LAYER SKIN SUBSTITUTE AND A SPLIT THICKNESS
   SKIN GRAFT WITH NEGATIVE PRESSURE WOUND THERAPY
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Todd, J. R.; Zaman, K.; Bayat, A.] Plast & Reconstruct Surg Res, Manchester, Lancs, England.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1067-1927
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR-APR
PY 2011
VL 19
IS 2
BP A57
EP A57
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 728ML
UT WOS:000287878100200
DA 2026-07-24
ER

PT J
AU Fussey, JM
   Luesley, DM
   Sterne, GD
AF Fussey, Jonathan M.
   Luesley, David M.
   Sterne, Guy D.
TI Vaginoplasty: A Modern Approach A Report of 2 Cases
SO JOURNAL OF REPRODUCTIVE MEDICINE
LA English
DT Article
DE fibrin tissue sealant; grafting; skin; plastic surgery; split-thickness
   skin graft; surgical procedure; reconstructive; vacuum-assisted closure;
   vaginoplasty
AB BACKGROUND: Split-thickness skin graft vaginoplasty is one of many methods for vaginal reconstruction. In its 130-year history it has been modified by numerous authors in attempts to improve graft viability and neovaginal function. We describe a modern approach that aims to improve outcomes and reduce complications.
   CASES: Two cases of split-thickness skin graft vaginoplasty are presented in which the traditional Abbe-McIndoe technique was supplemented by the combined use of vacuum-assisted closure and fibrin tissue sealant. In both cases 100% graft survival and normal neovaginal function were observed, with no recipient site complications. Both patients mobilized on postoperative day 3, and both were sexually active 4 months postoperatively.
   CONCLUSION: This approach has not been described previously in the literature. The impressive results seen in these cases suggest that the use of vacuum-assisted closure and fibrin tissue sealant in combination may improve graft survival and resulting neovaginal function.
C1 City Hosp, Dept Gynecol, Birmingham B18 7QH, W Midlands, England.
   [Fussey, Jonathan M.] City Hosp, Dept Plast Surg, Birmingham B18 7QH, W Midlands, England.
C3 University of Birmingham; University of Birmingham
RP Fussey, JM (通讯作者)，City Hosp, Dept Plast Surg, Dudley Rd, Birmingham B18 7QH, W Midlands, England.
EM jfussey@doctors.org.uk
OI Fussey, Jonathan/0000-0001-9971-4334
CR Abbe R., 1898, Med. Rec, V54, P836
   Banister J B, 1938, Proc R Soc Med, V31, P1055
   Goessl A., 2005, EUR SURG, V37, P43, DOI 10.1007/s10353-004-0115-2
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   Tercan M, 2002, PLAST RECONSTR SURG, V109, P706, DOI 10.1097/00006534-200202000-00044
   Vedung Sigfrid, 1993, Journal of Burn Care and Rehabilitation, V14, P356, DOI 10.1097/00004630-199305000-00009
NR 6
TC 5
Z9 5
U1 0
U2 2
PU SCI PRINTERS & PUBL INC
PI ST LOUIS
PA PO DRAWER 12425 8342 OLIVE BLVD, ST LOUIS, MO 63132 USA
SN 0024-7758
J9 J REPROD MED
JI J. Reprod. Med.
PD SEP-OCT
PY 2013
VL 58
IS 9-10
BP 441
EP 444
PG 4
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 210UF
UT WOS:000323859500013
PM 24050035
DA 2026-07-24
ER

PT J
AU Motomura, H
   Ohashi, N
   Harada, T
   Muraoka, M
   Ishii, M
AF Motomura, Hisashi
   Ohashi, Natsuko
   Harada, Teruichi
   Muraoka, Michinari
   Ishii, Masaiiiitsu
TI Aggressive conservative therapy for refractory ulcer with diabetes
   and/or arteriosclerosis
SO JOURNAL OF DERMATOLOGY
LA English
DT Article
DE arteriosclerosis; diabetes; foot ulcer; trafermin; vacuum-assisted
   closure therapy
ID VACUUM-ASSISTED CLOSURE; LIMB SALVAGE; LOWER-EXTREMITY; EXPERIENCE; FOOT
AB A foot ulcer due to diabetes and/or arteriosclerosis obliterans (ASO) frequently results in an intractable condition that resists treatment. To cope with this condition, we have developed a combination therapy that includes conventional conservative therapy plus surgical therapy. This aggressive conservative therapy using aggressive debridement, trafermin (Fiblast Spray, Kaken, Japan) treatment and vacuum-assisted closure (VAC) therapy was adopted to treat seven patients suffering from diabetes and ASO-related refractory foot ulcer accompanied by bone exposure. With the exception of one patient who died during the treatment, the remaining six patients obtained limb salvage. The mean time to cure was 8.3 months. This approach should be considered before amputation. Some patients may refuse amputation or cannot tolerate highly invasive surgical treatment including tissue transplantation. In such cases, this aggressive conservative therapy can be employed as a highly useful and reproducible technique requiring simple techniques.
C1 Osaka City Univ, Grad Sch Med, Dept Plast & Reconstruct Surg, Abeno Ku, Osaka 5458585, Japan.
   Osaka City Univ, Grad Sch Med, Dept Dermatol, Abeno Ku, Osaka 5458585, Japan.
C3 Osaka Metropolitan University; Osaka Metropolitan University
RP Motomura, H (通讯作者)，Osaka City Univ, Grad Sch Med, Dept Plast & Reconstruct Surg, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, Japan.
EM motoniura@med.osaka-cu.ac.jp
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NR 7
TC 5
Z9 6
U1 0
U2 3
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 0385-2407
J9 J DERMATOL
JI J. Dermatol.
PD MAY
PY 2006
VL 33
IS 5
BP 353
EP 359
DI 10.1111/j.1346-8138.2006.00082.x
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 063NU
UT WOS:000239027300008
PM 16700669
OA Bronze
DA 2026-07-24
ER

PT J
AU Argenta, LC
   Morykwas, MJ
AF Argenta, LC
   Morykwas, MJ
TI Vacuum-assisted closure: A new method for wound control and treatment:
   Clinical experience
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article; Proceedings Paper
CT Annual Meeting of the
   American-Society-of-Plastic-and-Reconstructive-Surgeons
CY NOV 09-13, 1996
CL DALLAS, TX
SP Amer Soc Plast & Reconstruct Surgeons
ID FLUID; FIBRONECTIN; ELONGATION; ULCERS; SKIN
AB Despite numerous advances, chronic and other difficult-to-manage wounds continue to be a treatment challenge. Presented is a new subatmospheric pressure technique: vacuum-assisted closure (The V.A.C.). The V.A.C. technique entails placing an open-cell foam dressing into the wound cavity and applying a controlled subatmospheric pressure (125 mmHg below ambient pressure). Three hundred wounds were treated: 175 chronic wounds, 94 subacute wounds, and 31 acute wounds. Two hundred ninety-six wounds responded favorably to subatmospheric pressure treatment, with an increased rate of granulation tissue formation. Wounds were treated until completely closed, were covered with a split-thickness skin graft, or a flap was rotated into the healthy, granulating wound bed. The technique removes chronic edema, leading to increased localized blood flow, and the applied forces result in the enhanced formation of granulation tissue. Vacuum-assisted closure is an extremely efficacious modality for treating chronic and difficult wounds.
RP Argenta, LC (通讯作者)，WAKE FOREST UNIV, BOWMAN GRAY SCH MED, DEPT PLAST & RECONSTRUCT SURG, MED CTR BLVD, WINSTON SALEM, NC 27157 USA.
OI Morykwas, Michael/0009-0001-5547-5172
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NR 30
TC 1708
Z9 2623
U1 6
U2 154
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD JUN
PY 1997
VL 38
IS 6
BP 563
EP 576
DI 10.1097/00000637-199706000-00002
PG 14
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA XE010
UT WOS:A1997XE01000002
PM 9188971
DA 2026-07-24
ER

PT J
AU Argenta, LC
   Morykwas, MJ
   Marks, MW
   DeFranzo, AJ
   Molnar, JA
   David, LR
AF Argenta, Louis C.
   Morykwas, Michael J.
   Marks, Malcolm W.
   DeFranzo, Anthony J.
   Molnar, Joseph A.
   David, Lisa R.
TI Vacuum-assisted closure: State of clinic art
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID PRESSURE WOUND THERAPY; DIABETIC FOOT WOUNDS; SECURING SKIN-GRAFTS;
   SUBATMOSPHERIC PRESSURE; ABDOMINAL-WALL; POSTSTERNOTOMY MEDIASTINITIS;
   DEGLOVING INJURIES; DEFINITIVE CLOSURE; RANDOMIZED-TRIAL; FASCIAL
   CLOSURE
AB Treatment of wounds has been the cornerstone of plastic surgery since its inception. Vacuum-assisted closure provides a new paradigm that can be used in concert with a wide variety of standard existing plastic surgery techniques. It was originally developed as an alternative treatment for debilitated patients with chronic wounds. It has rapidly evolved into a widely accepted treatment of chronic and acute wounds, contaminated wounds, burns, envenomations, infiltrations, and wound complications from failed operations. The ease of technique and a high rate of success have encouraged its adaptation by thoracic, general, trauma, burn, orthopedic, urologic, as well as plastic surgeons. This article discusses multidisciplinary advances in the use of the vacuum-assisted closure technique over the past 10 years and its status as of 2006. Creative surgeons continue to regularly adapt the system to difficult problems. This technique in trained surgical hands greatly enhances the scope and safety of wound treatment.
C1 Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27157 USA.
C3 Wake Forest University
RP Argenta, LC (通讯作者)，Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Med Ctr Blvd, Winston Salem, NC 27157 USA.
EM largenta@wfubmc.edu
RI ; Molnar, Joseph/AEK-5540-2022
OI Morykwas, Michael/0009-0001-5547-5172; 
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NR 85
TC 228
Z9 281
U1 1
U2 12
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JUN
PY 2006
VL 117
IS 7
SU S
BP 127S
EP 142S
DI 10.1097/01.prs.0000222551.10793.51
PG 16
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 056UA
UT WOS:000238549400012
PM 16799380
DA 2026-07-24
ER

PT J
AU Hanasono, MM
   Skoracki, RJ
AF Hanasono, Matthew M.
   Skoracki, Roman J.
TI Securing skin grafts to microvascular free flaps using the
   vacuum-assisted closure (VAC) device
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE microvascular free flap; negative pressure dressing; vacuum-assisted
   closure (VAC) device
ID NEGATIVE-PRESSURE DRESSINGS; WOUND CONTROL; BOLSTER
AB We performed microvascular free muscle flaps on 5 patients using the vacuum-assisted closure (VAC) device (KCI, San Antonio, TX) to secure a split-thickness skin graft to the external surface of the flap in each case. This method of skin-graft fixation was selected in each case because of the complex 3-dimensional shape of the flap or because of concerns of inadequate fixation provided by conventional tie-over bolster techniques in regions that experience a significant amount of shear stress. All 5 flaps remained viable throughout the treatment course and all 5 patients experienced excellent skin-graft take. Also, decreased edema was noted in all 5 flaps. We conclude that the VAC device is a useful tool in the fixation of skin grafts to microvascular free flaps and that its use does not compromise free-flap viability.
C1 Univ Texas, MD Anderson Canc Ctr, Dept Plast Surg, Houston, TX 77030 USA.
C3 University of Texas System; UTMD Anderson Cancer Center
RP Hanasono, MM (通讯作者)，Univ Texas, MD Anderson Canc Ctr, Dept Plast Surg, 1515 Holcombe Blvd, Houston, TX 77030 USA.
EM mhanasono@mdanderson.org
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
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NR 8
TC 53
Z9 63
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-7043
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD MAY
PY 2007
VL 58
IS 5
BP 573
EP 576
DI 10.1097/01.sap.0000237638.93453.66
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 161RK
UT WOS:000246033000020
PM 17452846
DA 2026-07-24
ER

PT J
AU Fukui, M
   Matsuoka, Y
   Taketani, S
   Higasa, K
   Hihara, M
   Kuro, A
   Kakudo, N
AF Fukui, Michika
   Matsuoka, Yuki
   Taketani, Shigeru
   Higasa, Koichiro
   Hihara, Masakatsu
   Kuro, Atsuyuki
   Kakudo, Natsuko
TI Accelerated Angiogenesis of Human Umbilical Vein Endothelial Cells Under
   Negative Pressure Was Associated With the Regulation of Gene Expression
   Involved in the Proliferation and Migration
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE angiogenesis; HUVECs; migration; negative-pressure wound therapy;
   proliferation; RNA sequencing
ID VACUUM-ASSISTED CLOSURE; WOUND THERAPY; MECHANISM; TISSUE
AB Negative pressure has been used as a preferred therapy for wound healing; however, the mechanisms by which negative pressure promotes tissue restoration remain unclear. In the present study, RNA-sequencing analysis was performed to identify differentially expressed genes in human umbilical vein endothelial cells (HUVECs) exposed to negative pressure. Cell viability and DNA synthesis were examined using the cell counting kit-8 assay and bromodeoxyuridine incorporation, respectively. Cell migration was assessed using tube formation, Transwell, and wound healing assays. Activity of the serine/threonine kinase (AKT) signaling pathway was also examined by measuring the levels of phospho-paxicillin, phospho-focal adhesion kinase (p-FAK), and p-AKT1. The exposure of HUVECs to negative pressure enhanced cell proliferation and DNA synthesis. Negative pressure enhanced the migration and invasion of HUVECs, which was accompanied by upregulation of genes involved in angiogenesis, extracellular matrix organization, and cytoskeletal organization. The mRNA levels of growth factors, including placental growth factor and platelet-derived growth factor B, also increased. In addition, phosphorylation of paxicillin, focal adhesion kinase, and AKT increased under negative pressure. Collectively, the findings of this study demonstrated that negative pressure stimulates the angiogenic activity of HUVECs by increasing their proliferation and migration via activation of the AKT signaling pathway.
C1 [Fukui, Michika; Matsuoka, Yuki; Taketani, Shigeru; Hihara, Masakatsu; Kakudo, Natsuko] Kansai Med Univ, Dept Plast & Reconstruct Surg, Hirakata, Japan.
   [Higasa, Koichiro] Kansai Med Univ, Dept Genome Anal, Hirakata, Japan.
   [Kuro, Atsuyuki] Kansai Med Univ, Med Ctr, Dept Plast & Reconstruct Surg, Moriguchi, Osaka, Japan.
   [Fukui, Michika] 2-5-1 Shin-Machi, Hirakata, Osaka 5731010, Japan.
C3 Kansai Medical University; Kansai Medical University; Kansai Medical
   University
RP Fukui, M (通讯作者)，2-5-1 Shin-Machi, Hirakata, Osaka 5731010, Japan.
EM mekam0zunevaneva@gmail.com; matsuoyk@hirakata.kmu.ac.jp;
   atakechan.man9@gmail.com; higasa@genome.med.kyoto-u.ac.jp;
   hiharams@hirakata.kmu.ac.jp; kuroa@hirakata.kmu.ac.jp;
   kakudon@hirakata.kmu.ac.jp
FU Grants-in-Aid for Scientific Research [21H03548, 23K21722] Funding
   Source: KAKEN
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NR 45
TC 2
Z9 2
U1 1
U2 20
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD DEC
PY 2022
VL 89
IS 6
BP e51
EP e59
DI 10.1097/SAP.0000000000003298
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 6P8JQ
UT WOS:000891172800008
PM 36416703
DA 2026-07-24
ER

PT J
AU Hsiao, SFY
   Ma, H
   Wang, YH
   Wang, TH
AF Hsiao, Sara Fu-yin
   Ma, Hsu
   Wang, Yu-Hei
   Wang, Tien-Hsiang
TI Occlusive drainage system for split-thickness skin graft: A prospective
   randomized controlled trial
SO BURNS
LA English
DT Article
DE Negative pressure wound therapy; Occlusive drainage system;
   Split-thickness skin graft; Wound care; Wound dressing
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; DRESSINGS; LAYER; PAIN
AB Background: Split-thickness skin grafts are widely used in reconstruction of large area defects. Conventional postoperative recipient site care includes saline-moistened gauze with a protective layer of petroleum gauze and splints for immobilization. This method causes pain while changing the dressing. We designed a better occlusive drainage system for split thickness skin grafts. We compared the treatment effect and subjective evaluation of our occlusive drainage system with that of the conventional method for coverage of split-thickness skin grafts.
   Methods: A randomized controlled trial was carried out in patients who received split thickness skin grafts. Patients aged 24-76 years were randomly assigned to the occlusive drainage system or the conventional indirect wet dressing method. The status of graft take, pain, and subjective evaluations were compared.
   Results: Twenty-eight participants were enrolled, with 14 in each group. The percentage of graft take was no difference between the 2 groups. No wound infection developed. Patients in the occlusive drainage system group experienced less pain and greater satisfaction. All patients followed up for at least 3 months, and no hypertrophic scar formation was noted.
   Conclusion: Comparing with the indirect wet dressing method, this new method is practical for covering split-thickness skin grafts, causes less pain, and provides a better experience for patients. (C) 2016 Elsevier Ltd and ISBI. All rights reserved.
C1 [Hsiao, Sara Fu-yin; Ma, Hsu; Wang, Tien-Hsiang] Taipei Vet Gen Hosp, Dept Surg, Div Plast & Reconstruct Surg, 19-F,201,Sec 2,Shipai Rd, Taipei 11217, Taiwan.
   [Hsiao, Sara Fu-yin; Ma, Hsu; Wang, Tien-Hsiang] Natl Yang Ming Univ, Sch Med, Taipei, Taiwan.
   [Wang, Yu-Hei] Taipei Vet Gen Hosp, Dept Nursing, Taipei, Taiwan.
C3 Taipei Veterans General Hospital; National Yang Ming Chiao Tung
   University; Taipei Veterans General Hospital
RP Wang, TH (通讯作者)，Taipei Vet Gen Hosp, Dept Surg, Div Plast & Reconstruct Surg, 19-F,201,Sec 2,Shipai Rd, Taipei 11217, Taiwan.
EM wangts@vghtpe.gov.tw
RI Wang, Tien-Hsiang/AAJ-4677-2020
FU Taipei Veterans General Hospital [VGH-102-C-153]; Veterans General
   Hospital-National Yang-Ming University Excellent Physician Scientists
   Cultivation Program [103-V-B-063]
FX This work was supported by the Taipei Veterans General Hospital
   (VGH-102-C-153) and Taipei Veterans General Hospital-National Yang-Ming
   University Excellent Physician Scientists Cultivation Program, No.
   103-V-B-063.
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NR 21
TC 18
Z9 19
U1 0
U2 4
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0305-4179
EI 1879-1409
J9 BURNS
JI Burns
PD MAR
PY 2017
VL 43
IS 2
BP 379
EP 387
DI 10.1016/j.burns.2016.08.025
PG 9
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA EN2LI
UT WOS:000395841300018
PM 28341261
DA 2026-07-24
ER

PT J
AU Twine, CP
   Lane, IF
   Williams, IM
AF Twine, Christopher P.
   Lane, Ian F.
   Williams, Ian M.
TI Management of Lymphatic Fistulas After Arterial Reconstruction in the
   Groin
SO ANNALS OF VASCULAR SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MUSCLE FLAP COVERAGE; LYMPHOCUTANEOUS FISTULAS;
   SURGICAL-MANAGEMENT; VASCULAR PROCEDURES; GRAFT INFECTIONS; WOUND
   CONTROL; FIBRIN GLUE; COMPLICATIONS; SARTORIUS
AB Background: Since its original description in the British Medical Journal in 1978, the treatment of lymphatic fistulas in the groin remains contentious. Lymph leaks remain a common cause of morbidity in patients who have undergone groin dissection. The aim of this review was to examine the evidence for prevention and treatment of lymphatic fistulas after arterial surgery in the groin.
   Methods: A systematic review of the English language literature was undertaken to determine the success of the various treatment options described.
   Results: A comprehensive literature search identified 46 studies describing several treatment options for lymphatic fistulas. A qualitative synthesis of these studies was performed. There was no consensus definition of lymphatic fistula. Treatments reviewed were: conservative management; lymphatic ligation; vascularized muscle flaps; and negative pressure wound therapy (NPWT). Due to poor study quality and the paucity of data no one treatment could be identified as superior.
   Conclusions: There was no quantifiable cut-off for either the amount of lymphatic output or number of days postoperatively that leakage continued to help determine when conservative measures should be abandoned and surgical intervention undertaken. There is some evidence supporting use of vascularized muscle flaps to reduce the volume of lymphatic drainage and help prevent secondary graft infection. The use of NPWT is also promising, but must be weighed against the associated risk of anastomotic bleeding and requirement for additional inpatient stay.
C1 [Twine, Christopher P.; Lane, Ian F.; Williams, Ian M.] Univ Wales Hosp, Cardiff Reg Vasc Unit, Cardiff CF14 4XW, S Glam, Wales.
C3 Cardiff University
RP Williams, IM (通讯作者)，Univ Wales Hosp, Reg Vasc Unit, Heath Pk, Cardiff CF14 4XW, S Glam, Wales.
EM Ian.williams5@wales.nhs.uk
RI Twine, Christopher/GLS-2275-2022
OI Twine, Christopher/0000-0003-0385-5760
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NR 51
TC 34
Z9 44
U1 0
U2 7
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD NOV
PY 2013
VL 27
IS 8
BP 1207
EP 1215
DI 10.1016/j.avsg.2013.01.003
PG 9
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA 243CN
UT WOS:000326294300051
PM 23850312
DA 2026-07-24
ER

PT J
AU Fujii, T
   Kawasaki, M
   Katayanagi, T
   Okuma, S
   Masuhara, H
   Shiono, N
   Watanabe, Y
AF Fujii, Takeshiro
   Kawasaki, Muneyasu
   Katayanagi, Tomoyuki
   Okuma, Shinnosuke
   Masuhara, Hiroshi
   Shiono, Noritsugu
   Watanabe, Yoshinori
TI A Case of an Aortic Abscess around the Elephant Trunk
SO ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
DE aortic abscess; elephant trunk; prosthetic vascular graft infection;
   vacuum-assisted closure; omental flap
ID STERNAL WOUND-INFECTION; VACUUM-ASSISTED CLOSURE; IN-SITU PRESERVATION;
   GRAFT INFECTIONS; PROSTHETIC GRAFTS; THORACIC AORTA; MANAGEMENT;
   SURGERY; THERAPY
AB A 52-year-old male patient with a history of total arch replacement using the elephant trunk technique for acute aortic dissection 4 years before visited our hospital with the chief complaint of persistent fever. Chest computed tomography (CT) suggested prosthetic vascular graft infection, which was treated surgically after chemotherapy. The first surgery consisted of debridement of an abscess around the vascular graft and in the aorta around the elephant trunk, and thoracic descending aorta replacement and vacuum-assisted closure (VAC) in view of the risk of bleeding from the peripheral region of the elephant trunk. One week later, omental filling was performed as the second step. This is a very rare case of aortic abscess around the elephant trunk that could successfully be managed by graft-conserving treatment.
C1 [Fujii, Takeshiro; Kawasaki, Muneyasu; Katayanagi, Tomoyuki; Okuma, Shinnosuke; Masuhara, Hiroshi; Shiono, Noritsugu; Watanabe, Yoshinori] Toho Univ, Fac Med, Sch Med, Div Cardiovasc Surg,Dept Surg, Tokyo 1438541, Japan.
C3 Toho University
RP Fujii, T (通讯作者)，Toho Univ, Fac Med, Sch Med, Div Cardiovasc Surg,Dept Surg,Ota Ku, 6-11-1 Omorinishi, Tokyo 1438541, Japan.
EM fujiit@med.toho-u.ac.jp
RI MASUHARA, Hiroshi/G-3148-2011
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NR 19
TC 4
Z9 4
U1 0
U2 0
PU MEDICAL TRIBUNE INC
PI TOKYO
PA ED COMM ANNALS THORACIC CARDIOVASCULAR SURG, 2-1-30 KUDAN MINAMI,
   CHIYODA-KU, TOKYO, 102-0074, JAPAN
SN 1341-1098
EI 2186-1005
J9 ANN THORAC CARDIOVAS
JI Ann. Thorac. Cardiovasc. Surg.
PY 2015
VL 21
IS 6
BP 570
EP 573
DI 10.5761/atcs.cr.15-00141
PG 4
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA CZ0OL
UT WOS:000366805200012
PM 26226888
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Oczenski, W
   Waldenberger, F
   Nehrer, G
   Kneifel, W
   Swoboda, H
   Schwarz, S
   Fitzgerald, RD
AF Oczenski, W
   Waldenberger, F
   Nehrer, G
   Kneifel, W
   Swoboda, H
   Schwarz, S
   Fitzgerald, RD
TI Vacuum-assisted closure for the treatment of cervical and mediastinal
   necrotizing fasciitis
SO JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
LA English
DT Article
DE vacuum-assisted closure; necrotizing fasciitis; mediastinitis;
   complications; infections; wound treatment; sepsis
ID WOUND CONTROL
AB NECROTIZING FASCIITIS is a rare but life-threatening infection of the soft tissue that is characterized by widespread fascial necrosis sparing the skin and the underlying muscle. The clinical course is often characterized by a severe hyperacute sepsis and a very high mortality rate of up to 70%.(1-3) Localization in the neck is rare and usually occurs secondary to dental, pharyngeal, and tonsillar infections. Crucial in treatment is the early recognition of the disease and immediate aggressive surgical treatment.(4) The course of the disease is often complicated by the great amount of necrotic tissue causing infection and mutilation.
   The authors report a case of cervical necrotizing fasciitis arising from a peritonsillar abscess complicated by severe mediastinitis and septic shock and, for the first time in this context, the successful use of a vacuum-assisted closure technique as an adjunctive wound treatment.
C1 Vienna City Hosp Lainz, Dept Anesthesia & Intens Care, A-1130 Vienna, Austria.
   Lainz Hosp, Dept Cardiac Surg, Vienna, Austria.
   Lainz Hosp, Dept Plast Surg, Vienna, Austria.
   Lainz Hosp, Dept Otorhinolaryngol, Vienna, Austria.
   Ludwig Boltzmann Inst Econ Med Anesthesia & Inten, Vienna, Austria.
C3 Ludwig Boltzmann Institute; Ludwig Boltzmann Institute for Clinical
   Anesthesia & Intensive Care
RP Oczenski, W (通讯作者)，Vienna City Hosp Lainz, Dept Anesthesia & Intens Care, Wolkersbergenstr 1, A-1130 Vienna, Austria.
EM wolfgang.oczenski@wienkav.at
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Banerjee AR, 1996, J LARYNGOL OTOL, V110, P81, DOI 10.1017/S0022215100132797
   Bilton BD, 1998, AM SURGEON, V64, P397
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   Hersh RE, 2001, HEART SURG FORUM, V4, P211
   Lin C, 2001, PLAST RECONSTR SURG, V107, P1684, DOI 10.1097/00006534-200106000-00008
   Molnar JA, 2000, PLAST RECONSTR SURG, V105, P174, DOI 10.1097/00006534-200001000-00030
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
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   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
NR 11
TC 19
Z9 27
U1 0
U2 0
PU W B SAUNDERS CO
PI PHILADELPHIA
PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA
   19106-3399 USA
SN 1053-0770
J9 J CARDIOTHOR VASC AN
JI J. Cardiothorac. Vasc. Anesth.
PD JUN
PY 2004
VL 18
IS 3
BP 336
EP 338
DI 10.1053/j.jvca.2004.03.016
PG 3
WC Anesthesiology; Cardiac & Cardiovascular Systems; Respiratory System;
   Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Anesthesiology; Cardiovascular System & Cardiology; Respiratory System
GA 840MR
UT WOS:000222863400016
PM 15232816
DA 2026-07-24
ER

PT J
AU Satteson, ES
   Crantford, JC
   Wood, J
   David, LR
AF Satteson, Ellen S.
   Crantford, John Clayton
   Wood, Jeyhan
   David, Lisa R.
TI Outcomes of Vacuum-Assisted Therapy in the Treatment of Head and Neck
   Wounds
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Head and neck reconstruction; head and neck wounds; negative pressure
   wound therapy; subatmospheric pressure therapy; vacuum-assisted closure
AB Introduction: Head and neck wounds can present a reconstructive challenge for the plastic surgeon. Whether from skin cancer, trauma, or burns, there are many different treatment modalities used to dress and manage complex head and neck wounds. Vacuum-assisted closure (VAC) therapy has been used on wounds of nearly every aspect of the body but not routinely in the head and neck area. This study was conducted to demonstrate our results using the VAC in the treatment of complex head and neck wounds.
   Methods: This is an IRB-approved, retrospective review of 69 patients with 73 head and neck wounds that were managed using the VAC between 1999 and 2008. The wound mechanism, location, and size, length of VAC therapy, patient comorbidities, use of radiation, complications, and ultimate outcome were assessed. In this patient population, the VAC was utilized because the standard reconstructive ladder was not a good option or had previously failed.
   Results: Sixty-nine patients with complex head and neck wounds were treated with the wound VAC. The mean age of the patients was 66 years, with a range of 5-96 years. Males outnumbered females in this study nearly 2:1. Eighty-six percent of patients had wounds secondary to cancer, 8% secondary to trauma, 3% secondary to infection, and 3% secondary to burns. The VAC was used as a dressing over skin grafts in 50%, over Integra in 21%, and over open debrided wounds in 29%. Wounds healed without complication in 44% of the skin grafts, 67% of Integra-covered wounds, and 71% of debrided wounds. Minor complications included failure of complete graft take, failure of granulation tissue formation in open debrided wounds, infection, and hematoma formation under skin grafts. Major complications included positive cancer margins requiring reexcision and death secondary to pulmonary embolism, sepsis, and metastatic cancer. Most complications resolved with dressing changes, repeat grafting, or the administration of antibiotics.
   Conclusions: Our results demonstrate that the wound VAC provides a reliable, effective, and durable dressing for a multitude of complex head and neck wounds. Additionally, it is a valuable tool when traditional surgical procedures are not a viable option.
C1 [Satteson, Ellen S.; Crantford, John Clayton; David, Lisa R.] Wake Forest Univ, Dept Plast & Reconstruct Surg, Sch Med, Med Ctr Blvd, Winston Salem, NC 27157 USA.
   [Wood, Jeyhan] Univ N Carolina, Sch Med, Div Plast & Reconstruct Surg, Chapel Hill, NC USA.
C3 Wake Forest University; University of North Carolina; University of
   North Carolina Chapel Hill; University of North Carolina School of
   Medicine
RP David, LR (通讯作者)，Wake Forest Univ, Dept Plast & Reconstruct Surg, Sch Med, Med Ctr Blvd, Winston Salem, NC 27157 USA.
EM ldavid@wakehealth.edu
CR Batacchi S, 2009, CRIT CARE, V13, DOI 10.1186/cc8193
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   Kanakaris NK, 2007, INJURY, V38, pS9, DOI 10.1016/j.injury.2007.10.029
   Llanos S, 2006, ANN SURG, V244, P700, DOI 10.1097/01.sla.0000217745.56657.e5
   Moisidis E, 2004, PLAST RECONSTR SURG, V114, P917, DOI 10.1097/01.PRS.0000133168.57199.E1
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   Molnar JA, 2000, PLAST RECONSTR SURG, V105, P174, DOI 10.1097/00006534-200001000-00030
   Perez D, 2010, AM J SURG, V199, P14, DOI 10.1016/j.amjsurg.2008.12.029
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   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Schimp VL, 2004, GYNECOL ONCOL, V92, P586, DOI 10.1016/j.ygyno.2003.10.055
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   Subramonia S, 2009, WORLD J SURG, V33, P931, DOI 10.1007/s00268-009-9947-z
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Zannis J, 2009, ANN PLAS SURG, V62, P407, DOI 10.1097/SAP.0b013e3181881b29
NR 19
TC 19
Z9 25
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD OCT
PY 2015
VL 26
IS 7
BP E599
EP E602
DI 10.1097/SCS.0000000000002047
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA VO0TC
UT WOS:001289276100004
PM 26468835
DA 2026-07-24
ER

PT J
AU Zutt, M
   Haas, E
   Krüger, U
   Distler, M
   Neumann, C
AF Zutt, Markus
   Haas, Ellen
   Krueger, Ullrich
   Distler, Meike
   Neumann, Christine
TI Successful use of vacuum-assisted closure therapy for leg ulcers caused
   by occluding vasculopathy and inflammatory vascular diseases -: A case
   series
SO DERMATOLOGY
LA English
DT Article
DE vacuum-assisted closure; leg ulcus; vasculitis; vaso-occlusion
ID WOUND MANAGEMENT
AB Background: Leg ulcers caused by vasculitis, small vessel occlusion or other rare conditions often prove to be very difficult to treat. Despite polypragmatic, systemic and localized therapy, many of these wounds are progressive and characterized by severe pain. Methods and Results: We here portray the cases of 5 patients with ulcers resistant to systemic therapy for the underlying disease, who were treated successfully using vacuum-assisted closure ( VAC) for wound management. We present the advantages and disadvantages of this method, as well as illustrating the essential and known therapeutic principles. Conclusions: Our experience shows VAC to be an excellent and effective alternative in the treatment of therapy-resistant chronic wounds caused by vasculopathy (small vessel occlusion or vasculitis). We did not observe any pathergy or proinflammatory effects caused by VAC. Copyright (c) 2007 S. Karger AG, Basel
C1 Univ Gottingen, Abt Dermatol & Venerol, Dept Dermatol & Venerol, DE-37075 Gottingen, Germany.
C3 University of Gottingen
RP Zutt, M (通讯作者)，Univ Gottingen, Abt Dermatol & Venerol, Dept Dermatol & Venerol, Von Siebold Str 3, DE-37075 Gottingen, Germany.
EM mzutt@gwdg.de
CR Chester DL, 2002, BRIT J PLAST SURG, V55, P510, DOI 10.1054/bjps.2002.3890
   Daróczy J, 2006, DERMATOLOGY, V212, P82, DOI 10.1159/000089204
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Gwan-Nulla DN, 2001, ANN PLAS SURG, V47, P552, DOI 10.1097/00000637-200111000-00014
   KOPP J, 2003, WOUND REPAIR REGEN, V11
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Shi W, 2003, SURF ENG, V19, P279, DOI [10.1179/026708403322499209, 10.1179/026708403225006221]
   *WEINB GROUP INC, 1999, TECHN ASS VAC HOM TR
   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
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   Willy C, 2005, VAKUUMTHERAPIE GRUND
NR 11
TC 19
Z9 19
U1 0
U2 0
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 1018-8665
J9 DERMATOLOGY
JI Dermatology
PY 2007
VL 214
IS 4
BP 319
EP 324
DI 10.1159/000100882
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 162CF
UT WOS:000246063700008
PM 17460403
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU van Kessel, CS
   Mendes, C
   Young, CJ
AF van Kessel, Charlotte S.
   Mendes, Colleen
   Young, Christopher J.
TI Peristomal Necrosis Following Cytoreductive Surgery and Hyperthermic
   Intraperitoneal Chemotherapy: A Case Report
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Abcarian stoma; Colostomy; Ileostomy; Multidisciplinary approach; NPWT
   therapy; Peristomal necrosis; Stoma; Wound debridement
ID VACUUM-ASSISTED CLOSURE; STOMA; COMPLICATIONS; ILEOSTOMY; MORBIDITY;
   LIFE
AB BACKGROUND: Peristomal necrosis is a rare but challenging condition requiring multidisciplinary management involving surgical debridement and intensive WOC nurse management.
   CASE: Mr T was a 56-year-old man who underwent cytoreductive surgery with intraperitoneal chemotherapy for a high-grade appendiceal neoplasm. As part of the procedure, an Abcarian stoma (end-ileostomy with a distal lumen from the transverse colon brought out flush with skin beside the proximal stoma) was created. Postoperatively there was leakage of effluent under the subcutaneous skin resulting in full-thickness necrosis of the peristomal area requiring surgical debridement. Consequently, a large peristomal skin defect occurred, resulting in difficulty achieving a good seal of the ostomy pouching system. To overcome these challenges, a multidisciplinary approach with WOC nurses, colorectal surgeons, and plastic surgeons was implemented. Initially, the defect was managed with a negative pressure wound therapy system, followed by a primary closure of the peristomal skin by the plastic surgeons. Mr T was discharged to home 58 days after his initial surgery; by that time, the peristomal skin was healed and he was able to manage ostomy pouching changes independently. Eight months later his ileostomy was successfully reversed.
   CONCLUSIONS: Large peristomal defects are challenging but can be managed successfully via a multidisciplinary approach including WOC nurses, colorectal surgeons, and plastic surgeons.
C1 [van Kessel, Charlotte S.; Young, Christopher J.] Royal Pnnce Alfred Hosp, Dept Colorectal Surg, Sydney, NSW, Australia.
   [Mendes, Colleen] Royal Prince Alfred Hosp, Dept Stomal Therapy, Sydney, NSW, Australia.
C3 University of Sydney; NSW Health; Royal Prince Alfred Hospital
RP van Kessel, CS (通讯作者)，Royal Prince Alfred Hosp, Surg Outcome & Res Unit, Sydney, NSW, Australia.
EM charlottevankessel@hotmail.com
RI Young, Christopher John/JTZ-5903-2023
OI Young, Christopher John/0000-0002-7213-5137
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NR 19
TC 0
Z9 0
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD NOV-DEC
PY 2022
VL 49
IS 6
BP 564
EP 569
DI 10.1097/WON.0000000000000914
PG 6
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 8R9XV
UT WOS:000928240300012
PM 36417381
DA 2026-07-24
ER

PT J
AU Boateng, J
   Catanzano, O
AF Boateng, Joshua
   Catanzano, Ovidio
TI Advanced Therapeutic Dressings for Effective Wound HealingA Review
SO JOURNAL OF PHARMACEUTICAL SCIENCES
LA English
DT Review
DE natural products; wound healing; polymeric biomaterials; macromolecular
   drug delivery; tissue engineering
ID HYPERBARIC-OXYGEN THERAPY; IN-VITRO EFFICACY; VACUUM-ASSISTED CLOSURE;
   MESENCHYMAL STEM-CELLS; DRUG-DELIVERY SYSTEM; GROWTH-FACTORS;
   NEGATIVE-PRESSURE; ANTIMICROBIAL PEPTIDES; PLATELET LYSATE; DOUBLE-BLIND
AB Advanced therapeutic dressings that take active part in wound healing to achieve rapid and complete healing of chronic wounds is of current research interest. There is a desire for novel strategies to achieve expeditious wound healing because of the enormous financial burden worldwide. This paper reviews the current state of wound healing and wound management products, with emphasis on the demand for more advanced forms of wound therapy and some of the current challenges and driving forces behind this demand. The paper reviews information mainly from peer-reviewed literature and other publicly available sources such as the US FDA. A major focus is the treatment of chronic wounds including amputations, diabetic and leg ulcers, pressure sores, and surgical and traumatic wounds (e.g., accidents and burns) where patient immunity is low and the risk of infections and complications are high. The main dressings include medicated moist dressings, tissue-engineered substitutes, biomaterials-based biological dressings, biological and naturally derived dressings, medicated sutures, and various combinations of the above classes. Finally, the review briefly discusses possible prospects of advanced wound healing including some of the emerging physical approaches such as hyperbaric oxygen, negative pressure wound therapy and laser wound healing, in routine clinical care. (c) 2015 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 104:3653-3680, 2015
C1 [Boateng, Joshua; Catanzano, Ovidio] Univ Greenwich, Fac Sci & Engn, Dept Pharmaceut Chem & Environm Sci, Chatham ME4 4TB, Kent, England.
C3 University of Greenwich
RP Boateng, J (通讯作者)，Univ Greenwich, Fac Sci & Engn, Dept Pharmaceut Chem & Environm Sci, Chatham ME4 4TB, Kent, England.
EM J.S.Boateng@gre.ac.uk
RI Boateng, Joshua/C-2006-2008; Catanzano, Ovidio/B-8744-2017
OI Boateng, Joshua/0000-0002-6310-729X; Catanzano,
   Ovidio/0000-0002-8284-0841
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NR 361
TC 787
Z9 872
U1 6
U2 903
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0022-3549
EI 1520-6017
J9 J PHARM SCI-US
JI J. Pharm. Sci.
PD NOV
PY 2015
VL 104
IS 11
BP 3653
EP 3680
DI 10.1002/jps.24610
PG 28
WC Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology &
   Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pharmacology & Pharmacy; Chemistry
GA CT7GY
UT WOS:000362984100004
PM 26308473
DA 2026-07-24
ER

PT J
AU Gaus, M
   Rohn, K
   Roetting, AK
AF Gaus, Moritz
   Rohn, Karl
   Roetting, Anna K.
TI Applicability and effect of a vacuum-assisted wound therapy after median
   laparotomy in horses
SO PFERDEHEILKUNDE
LA English
DT Article
DE horse; ventral median laparotomy; colic; wound healing complication;
   negative pressure wound therapy; vacuum-assisted closure
ID NEGATIVE-PRESSURE; COMPLICATION RATES; SURGICAL INCISIONS; TERM
   SURVIVAL; PART 1; CLOSURE; RISK; INFECTIONS; PREVENTION; MANAGEMENT
AB In a randomized, prospective, clinical trial the applicability of a vacuum therapy system was evaluated at the ventral abdomen in 50 horses with laparotomy due to acute abdominal pain. The effects on the incidence of wound healing complications after ventral median laparotomy in horses with acute abdominal pain is described. The horses were allocated to the treatment or control group after laparotomy and equipped with a wound dressing and a vacuum (125 mmHg) or with the wound dressing alone. Relevant parameters were collected preoperatively, intraoperatively, six consecutive days postoperatively, and three and eight weeks after surgery. Pre-, intra- and postoperative parameters were not significantly different between the groups. Nine horses (36%) in the treatment group and four horses (16%) in the control group developed a wound healing complication. This difference was not statistically significant and neither were the differences in oedema formation and the occurrence of dehiscence. No significant differences concerning exudation, oedema or dehiscence were found between the groups three and eight weeks after surgery. Overall, the vacuum system used in this study is an easy to apply system for general use at the ventral abdomen of the horse, with good toleration by the patients. The results indicate that the use of vacuum therapy for primary closed wounds after median laparotomy has no beneficial effect on wound healing.
C1 [Gaus, Moritz; Roetting, Anna K.] Univ Vet Med Hannover, Equine Clin, Hannover, Germany.
   [Rohn, Karl] Univ Vet Med Hannover, Inst Biometry Epidemiol & Informat Proc, Hannover, Germany.
C3 University of Veterinary Medicine Hannover; University of Veterinary
   Medicine Hannover
RP Gaus, M (通讯作者)，Vet Univ Hannover Fdn, Clin Horses, Buenteweg 9, D-30559 Hannover, Germany.
EM moritz.gaus@tiho-hannover.de
FU KCI Medizinprodukte GmbH, Germany
FX This study was supported by KCI Medizinprodukte GmbH, Germany, with the
   supply of the vacuum pump systems. We would like to thank all our
   interns for their intense assistance throughout the study, especially
   for the wound dressing applications during night hours.
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NR 32
TC 7
Z9 8
U1 0
U2 3
PU HIPPIATRIKA VERLAG MBH
PI STUTTGART
PA POSTFACH 102251, 70018 STUTTGART, GERMANY
SN 0177-7726
J9 PFERDEHEILKUNDE
JI Pferdeheilkunde
PD NOV-DEC
PY 2017
VL 33
IS 6
BP 563
EP 572
DI 10.21836/PEM20170604
PG 10
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA FW3JN
UT WOS:000425202800004
OA Bronze
DA 2026-07-24
ER

PT J
AU Deborre, C
   Ezissi, A
   Jaenisch, M
   Khoury, M
   Burger, C
   Randau, TM
   Kohlhof, H
AF Deborre, Christoph
   Ezissi, Afoma
   Jaenisch, Max
   Khoury, Mona
   Burger, Christof
   Randau, Thomas Martin
   Kohlhof, Hendrik
TI Use of a Negative-Pressure Wound Dressing to Prevent Surgical Site
   Complications after Revision Knee Arthroplasty-A Randomized Controlled
   Trial
SO APPLIED SCIENCES-BASEL
LA English
DT Article
DE knee; revision; arthroplasty; negative-pressure wound dressing
ID VACUUM-ASSISTED CLOSURE; QUALITY-OF-LIFE; TOTAL HIP; JOINT INFECTION;
   THERAPY; REPLACEMENT; OUTCOMES; SURGERY; RISK; AGE
AB The aim of this study was to determine if a negative pressure wound therapy (NPWT) system can facilitate wound healing and withstand mechanical stress owing to the high range of motion of the knee joint in total knee arthroplasty. The benefits of NPWT include aiding wound granulation and a reduction in wound edema and secretion; our goal is to investigate its benefits in primary wound closure. Within an eight-day duration of treatment, we compared standard wound dressing (gauze and compression) with the disposable NPWT system (PICO)(TM). A total of 79 patients were recruited in a controlled, randomized, prospective, single-institution clinical trial. A total of 40 patients were allocated to the study group and 39 to the control group. In terms of blood loss and infection parameters, there was no significant difference between both groups. In the NPWT group, we determined a significant reduction in wound edema but none in wound secretion. While the NPWT dressings survived the mechanical effects of movement during postoperative physiotherapy, conventional compressive dressings were often renewed. Even though the risk factors that could lead to delayed wound healing were reduced in the test group, we could not identify any significant difference pertaining to delayed wound healing that required surgical treatment.
C1 [Deborre, Christoph; Ezissi, Afoma; Jaenisch, Max; Khoury, Mona; Burger, Christof; Randau, Thomas Martin; Kohlhof, Hendrik] Univ Hosp Bonn, Dept Orthopaed & Traumatol, Venusberg Campus 1, D-53127 Bonn, Germany.
C3 University of Bonn
RP Jaenisch, M (通讯作者)，Univ Hosp Bonn, Dept Orthopaed & Traumatol, Venusberg Campus 1, D-53127 Bonn, Germany.
EM chrisdeborre@gmx.de; aezissi@googlemail.com; max.jaenisch@ukbonn.de;
   mona.khoury@ukb.uni-bonn.de; christof.burger@ukb.uni-bonn.de;
   thomassandau@ukb.uni-bonn.de; hendrik.kohlhof@ukb.uni-bonn.de
RI Randau, Thomas/AEP-9749-2022; Kohlhof, Hendrik/IYS-6108-2023; Jaenisch,
   Max/KXR-7055-2024
OI Randau, Thomas/0000-0002-5224-9639; Jaenisch, Max/0000-0001-5998-0224
FU Smith and Nephew, London, Great Britain [N-014.0099]
FX E.A. received a personal grant from Smith and Nephew, London, Great
   Britain (N-014.0099).
CR [Anonymous], Surgical site infections: prevention and treatment
   [Anonymous], BONE JOINT J
   [Anonymous], SINGL US NEG PRESS W
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NR 36
TC 1
Z9 1
U1 0
U2 3
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2076-3417
J9 APPL SCI-BASEL
JI Appl. Sci.-Basel
PD OCT
PY 2021
VL 11
IS 19
AR 9102
DI 10.3390/app11199102
PG 11
WC Chemistry, Multidisciplinary; Engineering, Multidisciplinary; Materials
   Science, Multidisciplinary; Physics, Applied
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Chemistry; Engineering; Materials Science; Physics
GA WH3HC
UT WOS:000707572400001
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Badia, JM
   Rubio-Pérez, I
   Morales-Pérez, C
   Bueno-Lledo, J
   Rodríguez-Lorenzo, LM
   Sancho, J
   Marín-Peña, O
   Lopez, S
   Masià, J
   Balibrea, JM
AF Badia, Josep M.
   Rubio-Perez, Ines
   Morales-Perez, Carlos
   Bueno-Lledo, Jose
   Rodriguez-Lorenzo, Laura M.
   Sancho, Joan
   Marin-Pena, Oliver
   Lopez, Susana
   Masia, Jaume
   Balibrea, Jose M.
TI Closed-Incision Negative Pressure Therapy: Scoping Review and
   Multidisciplinary Consensus Recommendations of the Spanish Observatory
   of Infection in Surgery
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE consensus recommendation; negative-pressure wound therapy;
   seroma/prevention and control*; surgical wound infection/epidemiology;
   surgical wound*/complications; wound healing
ID SURGICAL SITE INFECTION; VACUUM-ASSISTED CLOSURE; CHARLSON COMORBIDITY
   INDEX; WOUND THERAPY; COMPLICATIONS; METAANALYSIS; PREVENTION; EFFICACY;
   IMPACT; COSTS
AB Surgical site infections (SSI) and surgical site complications (SSC) significantly impact surgery outcomes, increasing hospital stays and mortality rates, and negatively affecting patients' quality of life. Closed-incision negative pressure therapy (ciNPT) emerged as a prophylactic strategy to reduce these complications. However, its applicability across different surgical procedures remains unclear. A scoping review was conducted to synthesise the available evidence on the use of ciNPT in different surgical contexts. A multidisciplinary panel of experts from different surgical specialties was assembled to identify patient risk factors for SSCs specific to each modality. Surgical procedures were categorised based on anticipated SSC rates and the impact of SSI. A decision diagram was finally developed, providing tailored recommendations for ciNPT use according to individual surgical circumstances. The findings of the review indicate that ciNPT effectively reduces SSI and SSC in most surgical procedures. Key patient-related factors influencing outcomes, such as age, obesity, and malnutrition, were outlined. Additionally, a specialty-based list of surgical procedures was compiled, specifying whether ciNPT is recommended, not recommended, or conditionally recommended based on specific criteria. This study underscores the benefits of ciNPT and provides a comprehensive guide to its application across several surgical specialties, aiming to optimise patient management and inform clinical practise.
C1 [Badia, Josep M.] Hosp Gen Granollers, Dept Surg, Granollers, Spain.
   [Badia, Josep M.] Univ Int Catalunya, Barcelona, Spain.
   [Rubio-Perez, Ines] Hosp Univ La Paz, Dept Surg, Madrid, Spain.
   [Morales-Perez, Carlos] Cent Univ Hosp Asturias HUCA, Cardiac Surg Serv, Oviedo, Spain.
   [Bueno-Lledo, Jose] Hosp Univ & Politecn La Fe, Dept Surg, Unit Abdominal Wall, Valencia, Spain.
   [Bueno-Lledo, Jose] Univ Valencia, Valencia, Spain.
   [Rodriguez-Lorenzo, Laura M.] Hosp Univ Parc Tauli, Dept Vasc Surg, Sabadell, Spain.
   [Sancho, Joan] Hosp Mar, Dept Surg, Barcelona, Spain.
   [Marin-Pena, Oliver] Hosp Univ Infanta Leonor, Dept Orthoped Surg & Traumatol, Madrid, Spain.
   [Lopez, Susana; Masia, Jaume] Hosp Univ St Pau, Dept Plast Surg, Barcelona, Spain.
   [Balibrea, Jose M.] Hosp Univ Germans Trias, Dept Surg, Endocrine Metab & Bariatr Surg Unit, Badalona, Spain.
   [Balibrea, Jose M.] Univ Autonoma Barcelona, Barcelona, Spain.
C3 Universitat Internacional de Catalunya (UIC); Hospital Universitario La
   Paz; Central University Hospital Asturias; Hospital Universitari i
   Politecnic La Fe; University of Valencia; Autonomous University of
   Barcelona; Parc Tauli Hospital Universitari; Hospital del Mar Research
   Institute; Hospital del Mar; Hospital Universitario Infanta Leonor;
   Hospital Germans Trias i Pujol; Autonomous University of Barcelona
RP Badia, JM (通讯作者)，Hosp Gen Granollers, Dept Surg, Granollers, Spain.; Badia, JM (通讯作者)，Univ Int Catalunya, Barcelona, Spain.
EM jmbadiaperez@gmail.com
RI ; Bueno-Lledó, Jose/I-2674-2019; MARIN-PEÑA, OLIVER/I-6265-2019;
   Balibrea, José M/V-5007-2019; Badia, Josep M/IVV-5872-2023
OI ROIGUEZ LORENZO, LAURA/0000-0003-2977-4627; Masia,
   Jaume/0000-0003-0141-9586; Bueno-Lledó, Jose/0000-0002-3116-5022;
   MARIN-PEÑA, OLIVER/0000-0002-7814-5766; Balibrea, José
   M/0000-0002-0764-7179; Badia, Josep M/0000-0003-2928-5233; Rubio-Perez,
   Ines/0000-0002-3960-6865
FU Smith+Nephew
FX Writing/editorial support was funded by Smith+Nephew, which also
   provided the funding for the travel and accommodation of the panellists
   during the meetings. Smith+Nephew market the PICO Single-use Negative
   Pressure Wound Therapy System. The funding source had no role in the
   study design, data analysis, data interpretation, expert conclusions and
   recommendations, or report writing. All authors submitted disclosure
   statements in accor-dance with JMI guidelines and format
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NR 133
TC 3
Z9 3
U1 3
U2 4
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT 6
PY 2025
VL 22
IS 10
AR e70750
DI 10.1111/iwj.70750
PG 15
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA E9454
UT WOS:001623047000001
PM 41054272
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Fluieraru, S
   Bekara, F
   Naud, M
   Herlin, C
   Faure, C
   Trial, C
   Téot, L
AF Fluieraru, S.
   Bekara, F.
   Naud, M.
   Herlin, C.
   Faure, C.
   Trial, C.
   Teot, L.
TI Sterile-water negative pressure instillation therapy for complex wounds
   and NPWT failures
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE instillation; negative pressure therapy; complex wounds; granulation
   tissue formation; surgical closure
ID VACUUM-ASSISTED CLOSURE; MULTICENTER; FOAM
AB Objective: To investigate use of negative pressure wound therapy (NPWT) combined with instillation for patients either presenting with a complex wound or after failure of classic NPWT.
   Method: A retrospective case series study conducted on patients treated using an NPWT instillation system (V.A.C. Instill; KCI Inc.) from January to December 2012. The instillation machine was used with pure saline so as not to interfere with local antibacterial solutions. Two clinical indications-patients presenting either large undermining, deep inaccessible wounds or infected wounds and those for whom conventional NPWT had proved ineffective, were analysed-with efficacy of the promotion of granulation tissue as the primary outcome. Length of instillation time, the rhythm and the amount of liquid to be injected compared with the estimated volume of the cavity were also evaluated.
   Results: Twenty-four patients were included in this series-12 post-NPWT failures and 12 complex wounds-with positive outcomes in 23 cases. Surgical closure was realised after promotion of granulation tissue, using either flaps or skin grafts alone, or combined with previous application of a dermal substitute. No complications linked to instillation were observed during the period of use.
   Conclusion: The results of this case series suggests that use of NPWT combined with pure saline instillation could have a positive impact on the healing trajectory of patients with complex wounds or after failure of classic NPWT.
C1 [Fluieraru, S.; Bekara, F.; Herlin, C.; Trial, C.; Teot, L.] Montpellier Univ Hosp, Dept Surg, Wound Healing Unit, Pole EMMBRUN, Montpellier, France.
   [Naud, M.; Faure, C.] Montpellier Univ Hosp, Med Device Unit, Dept Pharm, Montpellier, France.
C3 Universite de Montpellier; CHU de Montpellier; Universite de
   Montpellier; CHU de Montpellier
RP Fluieraru, S (通讯作者)，Montpellier Univ Hosp, Dept Surg, Wound Healing Unit, Pole EMMBRUN, Montpellier, France.
EM l-teot@chu-montpellier.fr
CR [Anonymous], COCHRANE DATABASE SY
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NR 23
TC 41
Z9 58
U1 0
U2 4
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD JUN
PY 2013
VL 22
IS 6
BP 293
EP 299
DI 10.12968/jowc.2013.22.6.293
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 157BX
UT WOS:000319871500002
PM 24049811
DA 2026-07-24
ER

PT J
AU Kubat, E
   Abaci, M
   Ünal, CS
AF Kubat, Emre
   Abaci, Malik
   Unal, Celal Selcuk
TI Z-plasty as an alternative choice for the treatment of recurrent local
   sternal wound infections
SO GENERAL THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
DE Z-plasty; Sternal wound infection; Sternotomy; Fasciocutaneous flap
ID VACUUM-ASSISTED CLOSURE; FASCIOCUTANEOUS FLAP; MUSCLE FLAPS;
   RISK-FACTORS; MANAGEMENT; SURGERY; CLASSIFICATION; MEDIASTINITIS
AB ObjectiveSternal wound infections after sternotomy are associated with high morbidity, high mortality, and prolonged hospital stay. The recurrence rate of sternal wound infections after single-stage closure is greater than expected. The aim of the study is to present our results of a consecutive series of Z-plasty for the treatment of recurrent sternal wound infections.MethodsBetween March 2015 and March 2017, a total of 9 patients were referred to our clinic with a recurrent sternal wound infection due to sternotomy with or without osteomyelitis. All patients previously underwent one or more surgical procedures for sternal infection. Negative pressure wound therapy and several debridement methods were performed before reconstruction. Two triangular double-transposition fasciocutaneous flap techniques as Z-plasty under local anesthesia was performed for all of the patients.ResultsThe flaps survived completely without any tissue loss. There were no major postoperative complications. One patient had recurrent infection after the flap procedure and was treated with antibiotic therapy. At 6months of follow-up, all of the patients were able to return to normal activities of daily living with a high patient satisfaction rate.ConclusionsLocal sternal wound reconstruction is an effective, rapid, and simple with Z-plasty associated with low recurrence risk. We believe that Z-plasty can be used for recurrent local sternal wound infections as an alternative treatment option for selected patients without mechanical dehiscence.
C1 [Kubat, Emre] Gulhane Training & Res Hosp, Dept Cardiovasc Surg, Gen Dr Tevfik Saglam Cd 1, TR-06010 Ankara, Turkey.
   [Abaci, Malik] Karabuk Training & Res Hosp, Dept Plast Reconstruct & Aesthet Surg, Karabuk, Turkey.
   [Unal, Celal Selcuk] Karabuk Training & Res Hosp, Dept Cardiovasc Surg, Karabuk, Turkey.
C3 Gulhane Training & Research Hospital
RP Kubat, E (通讯作者)，Gulhane Training & Res Hosp, Dept Cardiovasc Surg, Gen Dr Tevfik Saglam Cd 1, TR-06010 Ankara, Turkey.
EM ekubat@gmail.com
RI Abaci, Malik/A-2140-2019; Kubat, Emre/AAQ-3227-2021
OI Abaci, Malik/0000-0001-5145-9629; 
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NR 26
TC 2
Z9 3
U1 0
U2 3
PU SPRINGER JAPAN KK
PI TOKYO
PA SHIROYAMA TRUST TOWER 5F, 4-3-1 TORANOMON, MINATO-KU, TOKYO, 105-6005,
   JAPAN
SN 1863-6705
EI 1863-6713
J9 GEN THORAC CARDIOVAS
JI Gen. Thorac. Cardiovasc. Surg.
PD JUN
PY 2019
VL 67
IS 6
BP 518
EP 523
DI 10.1007/s11748-018-1052-5
PG 6
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA HZ4VQ
UT WOS:000468849900004
PM 30569256
DA 2026-07-24
ER

PT J
AU Jreije, S
   Fadel, M
   Karam, C
   Ghadieh, HE
   Ghanem, A
AF Jreije, Sasha
   Fadel, Marwan
   Karam, Carl
   Ghadieh, Hilda E.
   Ghanem, Antoine
TI Diabetes and Delayed Wound Healing: Molecular Mechanisms and
   Dermatological Interventions
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Review
DE diabetes mellitus; diabetic ulcers; regenerative medicine; therapeutics;
   wound healing
ID HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED CLOSURE; FOOT ULCERS; LEG
   ULCERS; MATRIX; INTERLEUKIN-1; INFLAMMATION; MANAGEMENT; DRESSINGS;
   EFFICACY
AB Diabetes mellitus is a global burden that affects wound healing at nearly every stage, transforming what should be a coordinated and self-limited repair process into a chronic, non-healing state. In diabetic patients, sustained hyperglycemia drives persistent inflammation, impaired angiogenesis, fibroblast dysfunction and extracellular matrix instability, resulting in refractory ulcers and often causing severe complications such as infection, hospitalisation, amputation and premature death. This review integrates mechanistic insights with dermatological advancements providing a comprehensive picture of diabetic wound pathophysiology and emerging therapeutic approaches. The normal sequence of wound healing is outlined and contrasted with the cellular and molecular derailments seen in diabetes, with a focus on macrophage polarisation, neutrophil dysfunction, mast cell and dendritic cell dysregulation, impaired regulatory T cell function, pericyte loss, disrupted neuroimmunomodulation, oxidative stress and defective tissue remodelling. Current and novel interventions including hyperbaric oxygen therapy, negative pressure wound therapy, advanced dressings, biologic grafts, phototherapy, as well as regenerative strategies involving stem cells, nanomaterials and exosome-based treatments are critically examined for their clinical utility, limitations and translational promise. No single modality fully addresses the multifactorial nature of diabetic wounds, but multimodal, mechanism-driven strategies hold potential to synergistically restore tissue repair. Bridging basic science with innovative dermatological interventions remains essential to reduce the global burden of diabetic wounds and improving quality of life for diabetics.
C1 [Jreije, Sasha; Fadel, Marwan; Karam, Carl; Ghadieh, Hilda E.] Univ Balamand, Fac Med & Med Sci, Dept Biomed Sci, Al Koura, Lebanon.
   [Ghanem, Antoine] St Joseph Univ, Fac Med, Dept Dermatol, Beirut, Lebanon.
   [Ghanem, Antoine] Clemenceau Med Ctr, Dept Dermatol, Dubai, U Arab Emirates.
C3 University Balamand; Saint Joseph University Beirut; American University
   of Beirut
RP Karam, C (通讯作者)，Univ Balamand, Fac Med & Med Sci, Dept Biomed Sci, Al Koura, Lebanon.
EM carl.karam@std.balamand.edu.lb
OI Fadel, Marwan/0009-0002-5880-3423; Karam, Carl/0009-0004-6499-8049
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NR 86
TC 0
Z9 0
U1 4
U2 4
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN 8
PY 2026
VL 23
IS 6
AR e70972
DI 10.1111/iwj.70972
PG 13
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA JD3IF
UT WOS:001786620800001
PM 42253027
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Mercut, R
   Sinna, R
   Vaucher, R
   Giroux, PA
   Assaf, N
   Lari, A
   Dast, S
AF Mercut, R.
   Sinna, R.
   Vaucher, R.
   Giroux, P. A.
   Assaf, N.
   Lari, A.
   Dast, S.
TI Triple flap technique for vulvar reconstruction
SO ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE
LA English
DT Article
DE Vulvar cancer; Reconstruction; V-Y advancement flaps; Pudendal
   perforator
ID VACUUM-ASSISTED CLOSURE; V-Y FLAP; ABDOMINOPERINEAL RESECTION; PERINEAL
   RECONSTRUCTION; VAGINAL RECONSTRUCTION; CANCER; MANAGEMENT
AB Objective. - Perineal defects are encountered ever more frequently, in the treatment of vulvar cancers or abdominoperineal resection. The surgical treatment of vulvar cancer leads to significant skin defect. The aim of the reconstruction is not to provide volume but rather to resurface perineum. We propose a new solution to cover the extensive skin defect remaining after excision.
   Methods. - We report 3 patients who underwent large excision for vulvar cancer, with lymph node dissection. For reconstruction, we performed 3 advancement flaps. Two V-Y flaps cantered on the infra-gluteal folds and based on pudendal perforator arteries were used to cover the postero-lateral parts of the defect. The third advancement flap from the superior aspect of the defect was a Y-V Mons pubis flap.
   Results. - The defects were successfully covered by the 3 flap technique. The first patient suffered a non-union that slowly healed by secondary intention. For the other cases, we used the same technique, but applied negative pressure wound therapy on the sutures, with excellent results.
   Conclusion. - The 3 flap technique is a simple and reliable method and the donor site morbidity is minimal. It can be realised without changing the position of the patient after tumour excision, and does not require delicate perforator dissection. This surgical option can be easily applied, allowing better management of these cases. (C) 2018 Elsevier Masson SAS. All rights reserved.
C1 [Mercut, R.; Sinna, R.; Vaucher, R.; Giroux, P. A.; Assaf, N.; Dast, S.] Univ Hosp Picardie, Dept Plast Reconstruct & Aesthet Surg, F-80054 Picardie 1, France.
   [Lari, A.] CHU Lyon, Serv Chirurg Plast Reconstructrice & Esthet, Hop Croix Rousse, 103 Grande Rue Croix Rousse, Lyon, France.
C3 CHU Lyon
RP Dast, S (通讯作者)，Amiens Univ Hosp, Dept Plast Reconstruct & Aesthet Surg, F-80054 Amiens 01, France.
EM s.dast@hotmail.fr
RI /AAR-2977-2021
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NR 18
TC 5
Z9 5
U1 0
U2 2
PU ELSEVIER
PI BRIDGEWATER
PA 685 ROUTE 202-206, BRIDGEWATER, NJ 08807 USA
SN 0294-1260
EI 1768-319X
J9 ANN CHIR PLAST ESTH
JI Ann. Chir. Plast. Esthet.
PD JUL
PY 2018
VL 63
IS 4
BP 343
EP 348
DI 10.1016/j.anplas.2018.03.007
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GN4VL
UT WOS:000439037400010
PM 29650262
DA 2026-07-24
ER

PT J
AU Desvigne, M
   Montgomery, K
   Holifield, K
   Day, K
   Gilmore, D
   Wardman, AL
AF Desvigne, Michael
   Montgomery, Krista
   Holifield, Kurt
   Day, Kari
   Gilmore, Denise
   Wardman, Ashley L.
TI Rotation Flap Closure of Pressure Injuries Following Negative Pressure
   Wound Therapy With Instillation for Wound Cleansing
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE closed incision negative pressure therapy; negative pressure wound
   therap with instillation and dwell time; pressure injury; pressure
   ulcer; surgical flaps; wound cleansing
ID VACUUM-ASSISTED CLOSURE
AB Introduction. Wound cleansing is integral during early-stage wound management and affords the transition to modalities promoting granulation tissue formation and reepithelialization, or preparation for wound coverage/closure. NPWTi-d includes periodic instillation of topical wound cleansing solutions and negative pressure for infectious material removal. Materials and Methods. This was a retrospective study of 5 patients who were admitted to an acute care hospital and treated for PI. After initial wound debridement, NPWTi-d instilled normal saline or HOCl solution (40 mL-80 mL) onto the wound for a dwell time of 20 minutes followed by 2 hours of subatmospheric pressure (-125 mm Hg). NPWTi-d duration was 3 to 6 days with 48-hour dressing changes. Results. NPWTi-d helped cleanse 10 PIs in 5 patients (age, 39-89 years) with comorbidities to facilitate primary closure using rotation flaps. In 4 patients, rotation flap closures were performed without immediate postoperative complications, followed by hospital discharge within 72 hours. In one patient, closure was preempted due to an unrelated medical issue. A stoma was created to prevent further contamination. The patient returned for flap coverage post colostomy. Conclusion. The findings herein support the use of NPWTi-d in the cleansing of complex wounds and suggest that it may facilitate an expedited transition to rotation flap closure for this wound type.
C1 [Desvigne, Michael; Montgomery, Krista; Holifield, Kurt; Day, Kari; Gilmore, Denise] Valley Wound Care Specialists, Peoria, IL USA.
   [Desvigne, Michael; Wardman, Ashley L.] Desvigne Plast Surg, Scottsdale, AZ USA.
   [Desvigne, Michael; Montgomery, Krista; Holifield, Kurt; Day, Kari; Gilmore, Denise] Abrazo Arrowhead Hosp, Glendale, AZ USA.
RP Desvigne, M (通讯作者)，Valley Wound Care Specialists, Wound Reconstruct, 24654 N Lake Pleasant Pkwy, Peoria, IL 85383 USA.
EM mndesvigne@yahoo.com
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NR 21
TC 1
Z9 1
U1 2
U2 7
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2023
VL 35
IS 4
BP E173
EP E177
DI 10.25270/wnds/20167
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA S5MQ2
UT WOS:001071610200007
PM 37220254
DA 2026-07-24
ER

PT J
AU Aref, R
   János, F
   Lóránd, C
   Roland, T
   Rezan, W
AF Aref, Rashed
   Janos, Fulop
   Lorand, Caicut
   Roland, Toth
   Rezan, Watti
TI The role of negative pressure wound therapy in the modern surgery
SO ORVOSI HETILAP
LA English
DT Article
DE modern wound care; wound therapy; wound healing; negative pressure
ID VACUUM-ASSISTED CLOSURE; PERFUSION
AB The introduction of negative pressure wound treatment in its current form into the daily surgical practice started in the 1990s. In addition to the suction of secretions, the aim of the treatment is to improve microcirculation and stimulate the granulation processes in the wound bed. Considering the modern wound management approach, the above method can be used to facilitate the wound healing process of both acute and chronic wounds. In the applica-tion of this method, it is important to emphasize the role of both the properly trained staff and the good patient selection. In our summary, we describe the components of the negative pressure system, the operation of wound care in this form, to present the different types of devices, and to identify the range of patients for whom the treatment can be used successfully. We cover the various technical methods of wound care systems, present the exact practice of treatment, the indications and contraindications, answer important questions that arise during treatment, draw atten-tion to possible complications and discuss how to eliminate them. There are special forms of negative pressure wound care (incisional, endoluminal, and intracavitary negative pressure wound care), which are also presented in detail, as well as application of this treatment in outpatient care. Finally, we draw attention to some special issues that may arise during negative pressure wound treatment, e.g., modification of anticoagulant therapy and treatment of wounds contaminated by multidrug-resistant pathogens.
C1 [Aref, Rashed; Janos, Fulop; Lorand, Caicut; Roland, Toth; Rezan, Watti] Pecsi Tud Egyet, Altalanos Orvostudomanyi Kar, Kihelyezett Szivsebeszeti Tanszek, Zala Megyei Szent Rafael Korhaz,Szivsebeszeti Osz, Zalaegerszeg, Hungary.
C3 University of Pecs
RP Aref, R (通讯作者)，Zrinyi M Ut 1, H-8900 Zalaegerszeg, Hungary.
EM aref.rashed.szv@zmkorhaz.hu
RI /AAO-3555-2020
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NR 34
TC 3
Z9 3
U1 0
U2 5
PU AKADEMIAI KIADO ZRT
PI BUDAPEST
PA BUDAFOKI UT 187-189-A-3, H-1117 BUDAPEST, HUNGARY
SN 0030-6002
EI 1788-6120
J9 ORVOSI HETILAP
JI Orvosi Hetilap
PD FEB
PY 2022
VL 163
IS 7
BP 271
EP 278
DI 10.1556/650.2022.32369
PG 8
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA ZF7JA
UT WOS:000759740300003
PM 35152209
OA Green Accepted, hybrid
DA 2026-07-24
ER

PT J
AU Wiegand, C
   White, R
AF Wiegand, Cornelia
   White, Richard
TI Microdeformation in wound healing
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MESENCHYMAL STEM-CELLS; EXTRACELLULAR-MATRIX;
   MECHANICAL STRETCH; TISSUE-RESPONSE; SCAR FORMATION; IN-VITRO;
   FIBROBLASTS; PRESSURE; FIBROSIS
AB Mechanical forces greatly influence cellular organization and behavior. Cells respond to applied stress by changes in form and composition until a suitable state is reestablished. However, without any mechanical stimuli cells stop proliferating, discontinue migration, go into cell-cycle arrest, and eventually die. Hence, one can assume that pathologies closely depending on cell migration like cancer or atherosclerosis might be governed by biophysical parameters. Moreover, mechanical cues will have fundamental effects in wound healing. Especially negative pressure wound therapy has the potential to endorse wound healing by induction of both macrodeformation (wound contraction) and microdeformation (tissue reactions at microscopic level). So far, the capacity for researchers to study the link between mechanical stimulation and biological response has been limited by the lack of instrumentation capable of stimulating the tissue in an appropriate manner. However, first reports on application of micromechanical forces to wounds elucidate the roles of cell stretch, substrate stiffness, and tissue deformation during cell proliferation and differentiation. This review deals with their findings and tries to establish a link between the current knowledge and the questions that are essential to clinicians in the field: What is the significance of mirodeformations for wound healing? Does dead space impede propagation of mechanical cues? How can microdeformations induce cell proliferation? What role do fibroblasts, myofibroblasts, and mesenchymal stem cells play in chronic wounds with regard to micromechanical forces?
C1 [Wiegand, Cornelia] Univ Med Ctr Jena, Dept Dermatol, D-07743 Jena, Germany.
   [White, Richard] Univ Worcester, Inst Hlth & Soc, Worcester, MA USA.
RP Wiegand, C (通讯作者)，Univ Med Ctr Jena, Dept Dermatol, Erfurter Str 35, D-07743 Jena, Germany.
EM c.wiegand@med.uni-jena.de
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NR 59
TC 41
Z9 52
U1 1
U2 37
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV
PY 2013
VL 21
IS 6
BP 793
EP 799
DI 10.1111/wrr.12111
PG 7
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 243OU
UT WOS:000326327100149
PM 24134318
DA 2026-07-24
ER

PT J
AU Straub, A
   Brands, R
   Borgmann, A
   Vollmer, A
   Hohm, J
   Linz, C
   Müller-Richter, U
   Kübler, AC
   Hartmann, S
AF Straub, Anton
   Brands, Roman
   Borgmann, Anna
   Vollmer, Andreas
   Hohm, Julian
   Linz, Christian
   Mueller-Richter, Urs
   Kuebler, Alexander C.
   Hartmann, Stefan
TI Free Skin Grafting to Reconstruct Donor Sites after Radial Forearm Flap
   Harvesting: A Prospective Study with Platelet-Rich Fibrin (PRF)
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE platelet-rich fibrin; free skin grafts; radial forearm flap; donor-site
   morbidity
ID FULL; CLOSURE; COMPLICATIONS; MORBIDITY
AB Reconstruction of the donor site after radial forearm flap harvesting is a common procedure in maxillofacial plastic surgery. It is normally carried out with split-thickness or full-thickness free skin grafts. Unfortunately, free skin graft transplantation faces wound healing impairments such as necrosis, (partial) graft loss, or tendon exposure. Several studies have investigated methods to reduce these impairments and demonstrated improvements if the wound bed is optimised, for example, through negative-pressure wound therapy or vacuum-assisted closure. However, these methods are device-dependent, expansive, and time-consuming. Therefore, the application of platelet-rich fibrin (PRF) to the wound bed could be a simple, cost-effective, and device-independent method to optimise wound-bed conditions instead. In this study, PRF membranes were applied between the wound bed and skin graft. Results of this study indicate improvements in the PRF versus non-PRF group (93.44% versus 86.96% graft survival, p = 0.0292). PRF applied to the wound bed increases graft survival and reduces impairments. A possible explanation for this is the release of growth factors, which stimulate angiogenesis and fibroblast migration. Furthermore, the solid PRF membranes act as a mechanical barrier ("lubrication" layer) to protect the skin graft from tendon motion. The results of this study support the application of PRF in donor-site reconstruction with free skin grafts.
C1 [Straub, Anton; Brands, Roman; Borgmann, Anna; Vollmer, Andreas; Hohm, Julian; Linz, Christian; Mueller-Richter, Urs; Kuebler, Alexander C.; Hartmann, Stefan] Univ Hosp Wurzburg, Dept Oral & Maxillofacial Plast Surg, Pleicherwall 2, D-97070 Wurzburg, Germany.
   [Mueller-Richter, Urs] Univ Hosp Wurzburg, Comprehens Canc Ctr Mainfranken, Josef Schneider Str 6, D-97080 Wurzburg, Germany.
   [Mueller-Richter, Urs] Bavarian Canc Res Ctr BZKF, D-91054 Erlangen, Germany.
C3 University of Wurzburg; University of Wurzburg
RP Straub, A (通讯作者)，Univ Hosp Wurzburg, Dept Oral & Maxillofacial Plast Surg, Pleicherwall 2, D-97070 Wurzburg, Germany.
EM straub_a@ukw.de; brandsr@ukw.de; borgmann_a@ukw.de; vollmer_a@ukw.de;
   hohm_j@ukw.de; linz_c@ukw.de; mueller_u2@ukw.de; kuebler_a@ukw.de;
   hartmann_s2@ukw.de
RI ; Vollmer, Andreas/ABD-1971-2021; Müller-Richter, Urs/P-5864-2014;
   Kübler, Alexander/ABA-9297-2021
OI Straub, Anton/0000-0002-9452-9380; Vollmer, Andreas/0000-0002-2697-5143;
   Müller-Richter, Urs/0000-0001-7869-7686; Linz,
   Christian/0000-0002-1155-8478
CR Andrews BT, 2006, LARYNGOSCOPE, V116, P1918, DOI 10.1097/01.mlg.0000235935.07261.98
   Braza ME, 2020, SPLIT THICKNESS SKIN
   Chang EI, 2020, PLAST RECONSTR SURG, V145, P1267, DOI 10.1097/PRS.0000000000006790
   Chen JG, 2020, INT WOUND J, V17, P1650, DOI 10.1111/iwj.13445
   Choukroun J, 2006, ORAL SURG ORAL MED O, V101, P299, DOI 10.1016/j.tripleo.2005.07.012
   Clark JM, 2019, J OTOLARYNGOL-HEAD N, V48, DOI 10.1186/s40463-019-0344-9
   Davis WJ, 2011, J HAND MICROSURG, V3, P18, DOI 10.1007/s12593-011-0036-9
   Di Giuli R, 2021, ANN PLAS SURG, V86, P655, DOI 10.1097/SAP.0000000000002777
   Dohan David M, 2006, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, V101, pe45, DOI 10.1016/j.tripleo.2005.07.009
   Ehrenfest DMD, 2009, TRENDS BIOTECHNOL, V27, P158, DOI 10.1016/j.tibtech.2008.11.009
   Ekström K, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0075227
   El Bagdadi K, 2019, EUR J TRAUMA EMERG S, V45, P467, DOI 10.1007/s00068-017-0785-7
   Mourao CFDB, 2020, J STOMATOL ORAL MAXI, V121, P84, DOI 10.1016/j.jormas.2019.02.011
   Ghanaati S, 2014, J ORAL IMPLANTOL, V40, P679, DOI 10.1563/aaid-joi-D-14-00138
   He L, 2009, ORAL SURG ORAL MED O, V108, P707, DOI 10.1016/j.tripleo.2009.06.044
   Huang FM, 2010, J ENDODONT, V36, P1628, DOI 10.1016/j.joen.2010.07.004
   Karimi A, 2007, J CRANIO MAXILL SURG, V35, P369, DOI 10.1016/j.jcms.2007.07.004
   Maciel J, 2014, TISSUE ENG PT A, V20, P250, DOI [10.1089/ten.tea.2012.0439, 10.1089/ten.TEA.2012.0439]
   Miron RJ, 2017, CLIN ORAL INVEST, V21, P1913, DOI 10.1007/s00784-017-2133-z
   Moreno-Sánchez M, 2016, J ORAL MAXIL SURG, V74, P204, DOI 10.1016/j.joms.2015.08.003
   Nica O, 2019, ROM J MORPHOL EMBRYO, V60, P581
   Pirraco RP, 2013, J TISSUE ENG REGEN M, V7, P392, DOI 10.1002/term.535
   Pohlenz P, 2012, INT J ORAL MAX SURG, V41, P739, DOI 10.1016/j.ijom.2012.02.012
   Richardson D, 1997, PLAST RECONSTR SURG, V99, P109, DOI 10.1097/00006534-199701000-00017
   Riecke B, 2015, INT J ORAL MAX SURG, V44, P937, DOI 10.1016/j.ijom.2015.02.021
   Tyagi A, 2021, CUREUS J MED SCIENCE, V13, DOI 10.7759/cureus.15160
   Vidrine DM, 2005, OTOLARYNG HEAD NECK, V133, P403, DOI 10.1016/j.otohns.2005.04.028
   Wend S, 2017, J MATER SCI-MATER M, V28, DOI 10.1007/s10856-017-5992-6
   Wu PIK, 2016, PHYS MED REH CLIN N, V27, P825, DOI 10.1016/j.pmr.2016.06.002
   Xia CY, 2014, MOL MED REP, V9, P1749, DOI 10.3892/mmr.2014.1997
NR 30
TC 14
Z9 14
U1 1
U2 4
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD JUN
PY 2022
VL 11
IS 12
AR 3506
DI 10.3390/jcm11123506
PG 12
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 2K6AB
UT WOS:000816415100001
PM 35743574
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Bassetto, F
   Lancerotto, L
   Salmaso, R
   Pandis, L
   Pajardi, G
   Schiavon, M
   Tiengo, C
   Vindigni, V
AF Bassetto, Franco
   Lancerotto, Luca
   Salmaso, Roberto
   Pandis, Laura
   Pajardi, Giorgio
   Schiavon, Mauro
   Tiengo, Cesare
   Vindigni, Vincenzo
TI Histological evolution of chronic wounds under negative pressure therapy
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article
DE Negative pressure therapy; VAC Therapy; Vacuum; Wound; Ulcer
ID VACUUM-ASSISTED CLOSURE; GROWTH; MECHANISMS
AB Background: Negative pressure wound therapy (NPT) has achieved widespread success in the treatment of difficult wounds. However, its effects are but partially explored, and investigations mostly concentrated at the wound-dressing interface; a detailed histological description of the evolution of wounds under NPT is still lacking.
   Materials and Methods: Subsequent punch biopsies of NPT-treated chronic wounds of human patients were analysed. Phenomena occurring in wounds were quantified by analysis of proliferating cells nuclear antigen (PCNA) (proliferating nuclei), CD31 (blood vessels), CD68p (macrophages) and CD45 (lymphocytes) stained slides.
   Results: Three layers were identified in day-0 wounds. Over time, under NPT, the layers behaved differently: the most superficial (1.5 mm) developed granulation tissue, constant in thickness, with high proliferation index, increased in blood vessels density and developed acute inflammation. Instead, the two deeper layers decreased in proliferation rate, maintained vessels density unchanged, were cleared of chronic inflammation and oedema and underwent progression towards stable tissue.
   Discussion: Indeed, while most research has focused on induction of superficial granulation tissue by NPT, deeper layers appear to be also affected, with relieving of chronic inflammation and tissue stabilisation. This may be an important and under-appreciated effect, playing a role in the known positive outcomes of NPT, such as better graft-taking rates. (C) 2011 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Bassetto, Franco; Lancerotto, Luca; Pandis, Laura; Tiengo, Cesare; Vindigni, Vincenzo] Univ Padua, Inst Plast Surg, Padua, Italy.
   [Salmaso, Roberto] Hosp Padova, Dept Pathol, Padua, Italy.
   [Pajardi, Giorgio] Univ Milan, Hand Surg Unit, Dept Plast Surg, Milan, Italy.
   [Schiavon, Mauro] Univ Hosp Udine, Div Plast Surg, Udine, Italy.
C3 University of Padua; University of Padua; Azienda Ospedaliera -
   Universita di Padova; University of Milan; University of Udine;
   University Hospital of Udine
RP Lancerotto, L (通讯作者)，Univ Padua, Inst Plast Surg, Padua, Italy.
EM luca.lancerotto@unipd.it
RI Lancerotto, Luca/A-5745-2013; Vindigni, Vincenzo/K-5059-2016
OI PAJARDI, GIORGIO EUGENIO/0000-0001-6232-034X; TIENGO,
   CESARE/0000-0002-7493-563X; Vindigni, Vincenzo/0000-0001-6638-9010
CR Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
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   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Pietramaggiori G, 2007, ANN SURG, V246, P896, DOI 10.1097/SLA.0b013e3180caa47f
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
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   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Wilkes R, 2009, J MECH BEHAV BIOMED, V2, P272, DOI 10.1016/j.jmbbm.2008.10.006
NR 28
TC 42
Z9 50
U1 0
U2 16
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD JAN
PY 2012
VL 65
IS 1
BP 91
EP 99
DI 10.1016/j.bjps.2011.08.016
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 863DW
UT WOS:000298144000021
PM 21885358
DA 2026-07-24
ER

PT J
AU Wetzel-Roth, W
AF Wetzel-Roth, W
TI VAC®-Therapy as a hygienic procedure tool: Protection of the environment
   of wounds and patients with multiresistant bacteria in clinical and
   outpatient treatment
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nurnberg, GERMANY
ID VACUUM-ASSISTED CLOSURE
C1 Buchloe Tagesklin, Belegarzt Stad Krankenhaus Schwabmunchen, D-86807 Buchloe, Germany.
RP Wetzel-Roth, W (通讯作者)，Facharzt Chirurg Thorax Kardiovaskularchirurg, Hindenburgstr 1, D-86807 Buchloe, Germany.
EM info@wetzel-roth.de
CR Horch R E, 2005, MMW Fortschr Med, V147 Suppl 1, P1
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   WILLY C, 2005, VAKUUMTHERAPIE
   2000, BGBL, V1, P1045
NR 5
TC 0
Z9 0
U1 0
U2 0
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S180
EP S181
DI 10.1055/s-2006-921516
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 034DB
UT WOS:000236904100044
PM 16575677
DA 2026-07-24
ER

PT J
AU Pichler, M
   Larcher, L
   Holzer, M
   Exler, G
   Thuile, T
   Gatscher, B
   Tappeiner, L
   Deluca, J
   Carriere, C
   Nguyen, VA
   Moosbrugger-Martinz, V
   Schmuth, M
   Klein, GF
   Eisendle, K
AF Pichler, Maria
   Larcher, Lorenz
   Holzer, Michael
   Exler, Gerald
   Thuile, Tobias
   Gatscher, Barbara
   Tappeiner, Lukas
   Deluca, Jenny
   Carriere, Cinzia
   Van Anh Nguyen
   Moosbrugger-Martinz, Verena
   Schmuth, Matthias
   Klein, Georg F.
   Eisendle, Klaus
TI Surgical treatment of pyoderma gangrenosum with negative pressure wound
   therapy and split thickness skin grafting under adequate
   immunosuppression is a valuable treatment option: Case series of 15
   patients
SO JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
LA English
DT Letter
C1 [Pichler, Maria; Thuile, Tobias; Gatscher, Barbara; Tappeiner, Lukas; Deluca, Jenny; Carriere, Cinzia; Eisendle, Klaus] Med Univ Innsbruck, Cent Teaching Hosp Bolzano Bozen, Dept Dermatol Venereol & Allergol, Acad Teaching Dept, Innsbruck, Austria.
   [Eisendle, Klaus] IMREST Interdisciplinary Med Res Ctr South Tyrol, Claudiana, Coll Hlth Care Profess, Bolzano, Italy.
   [Larcher, Lorenz] Paracelsus Med Univ Salzburg, Hosp St John God Salzburg, Dept Plast Aesthet & Reconstruct Surg, Salzburg, Austria.
   [Holzer, Michael; Van Anh Nguyen; Moosbrugger-Martinz, Verena; Schmuth, Matthias] Med Univ Innsbruck, Univ Dept Dermatol & Venereol, Innsbruck, Austria.
   [Exler, Gerald; Klein, Georg F.] Hosp Elisabethinen, Dept Dermatol, Linz, Austria.
C3 Medical University of Innsbruck; Paracelsus Private Medical University;
   Medical University of Innsbruck; Ordensklinikum Linz Elisabethinen
RP Eisendle, K (通讯作者)，Med Univ Innsbruck, Cent Teaching Hosp Bolzano Bozen, Dept Dermatol Venereol & Allergol, Acad Teaching Dept, Innsbruck, Austria.
EM Klauseisendle@hotmail.com
RI ; Eisendle, Klaus/H-6798-2019; Holzer, Michael/R-9784-2018
OI Schmuth, Matthias/0000-0002-4064-1334; Eisendle,
   Klaus/0000-0002-8234-9964; 
CR Binus AM, 2011, BRIT J DERMATOL, V165, P1244, DOI 10.1111/j.1365-2133.2011.10565.x
   Cabalag MS, 2015, ANN PLAS SURG, V74, P354, DOI 10.1097/SAP.0b013e31829565f3
   Ormerod AD, 2015, BMJ-BRIT MED J, V350, DOI 10.1136/bmj.h2958
   Pichler M, 2014, INT J DERMATOL, V53, P1520, DOI 10.1111/ijd.12616
   Webster J, 2014, COCHRANE DATABASE SY, V10
NR 5
TC 46
Z9 49
U1 0
U2 2
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0190-9622
J9 J AM ACAD DERMATOL
JI J. Am. Acad. Dermatol.
PD APR
PY 2016
VL 74
IS 4
BP 760
EP +
DI 10.1016/j.jaad.2015.09.009
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA DG0ZM
UT WOS:000371794800034
PM 26979359
OA Bronze
DA 2026-07-24
ER

PT J
AU Ehrl, D
   Heidekrueger, PI
   Broer, PN
   Erne, HC
AF Ehrl, Denis
   Heidekrueger, Paul I.
   Broer, P. Niclas
   Erne, Holger C.
TI Topical Negative Pressure Wound Therapy of Burned Hands: Functional
   Outcomes
SO JOURNAL OF BURN CARE & RESEARCH
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; THICKNESS SKIN-GRAFTS; SUBATMOSPHERIC PRESSURE;
   PROGRESSION; GLOVE; RECONSTRUCTION; DISABILITIES; MANAGEMENT; DIFFUSION;
   AUTOGRAFT
AB Extensive partial-and full-thickness burns, especially of the hands, continue to pose a surgical challenge. With improved knowledge regarding fluid balance, burn pathophysiology, and lately also given the introduction of topical negative pressure wound (TNPW) therapy, treatment regimes have changed in many burn centers. The authors evaluated the results regarding long-term outcomes of patients with partial-and full-thickness burns of the hands treated with TNPW. Over a period of 72 months, 51 patients with 80 hand burns received TNPW treatment. Medical records of all patients were reviewed retrospectively. All patients were further invited by letter, telephone, and/or email to participate in follow-up examinations. Finally, 30 patients with 47 involved hands participated in this study. Follow-up examinations were performed at a mean of 35 (range: 14-72) months postinjury. Measurements regarding the ability to completely dorsally extend the fingers and complete active fist closure showed no restrictions in 85.1 and 78.7% of cases. Mean Disabilities of the Arm, Shoulder, and Hand score among all patients was 13.8 (range: 0-35.8). Regarding the quality of the scars of the hand, 41 hands showed good quality with no signs of hypertrophic scar formation and 6 hands showed acceptable quality of scars with partial hypertrophic scar formation. In the authors' experience, TNPW therapy is a safe and effective modality to treat burns of the hand.
C1 [Ehrl, Denis; Heidekrueger, Paul I.; Broer, P. Niclas] Tech Univ Munich, Acad Teaching Hosp, StKM Klinikum Bogenhausen, Dept Plast Reconstruct Hand & Burn Surg, Munich, Germany.
   [Erne, Holger C.] Tech Univ Munich, Klinikum Rechts Isar, Dept Plast Surg & Hand Surg, Munich, Germany.
C3 Technical University of Munich; Munchen Klinik; Technical University of
   Munich
RP Ehrl, D (通讯作者)，Tech Univ Munich, Bogenhausen Acad Hosp, Dept Plast Reconstruct Hand & Burn Surg, Englschalkingerstr 77, D-81925 Munich, Germany.
EM Denis.Ehrl@klinikum-muenchen.de
RI ; Broer, Niclas/AAF-6580-2019; Heidekrueger, Paul/AAC-8342-2022
OI Ehrl, Denis/0000-0001-9394-8412; 
CR Adamkova M, 2005, Acta Chir Plast, V47, P24
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NR 43
TC 11
Z9 12
U1 0
U2 7
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1559-047X
EI 1559-0488
J9 J BURN CARE RES
JI J. Burn Care Res.
PD JAN-FEB
PY 2018
VL 39
IS 1
BP 121
EP 128
DI 10.1097/BCR.0000000000000557
PG 8
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA FW4UM
UT WOS:000425310400017
PM 28368916
DA 2026-07-24
ER

PT J
AU Orgill, DP
   Manders, EK
   Sumpio, BE
   Lee, RC
   Attinger, CE
   Gurtner, GC
   Ehrlich, HP
AF Orgill, Dennis P.
   Manders, Ernest K.
   Sumpio, Bauer E.
   Lee, Raphael C.
   Attinger, Christopher E.
   Gurtner, Geoffrey C.
   Ehrlich, H. Paul
TI The mechanisms of action of vacuum assisted closure: More to learn
SO SURGERY
LA English
DT Review
ID PRESSURE WOUND THERAPY; TOPICAL NEGATIVE-PRESSURE; SUBATMOSPHERIC
   PRESSURE; CELL-SHAPE; PROLIFERATION; PROGRESSION; ULCERS; STRAIN;
   GROWTH; SKIN
C1 [Orgill, Dennis P.] Brigham & Womens Hosp, Div Plast & Reconstruct Surg, Boston, MA 02115 USA.
   [Manders, Ernest K.] Univ Pittsburgh, Sch Med, Div Plast & Reconstruct Surg, Pittsburgh, PA USA.
   [Sumpio, Bauer E.] Yale Univ, Sch Med, Dept Surg, New Haven, CT 06510 USA.
   [Lee, Raphael C.] Univ Chicago Hosp, Dept Surg, Chicago, IL 60637 USA.
   [Attinger, Christopher E.] Georgetown Univ, Med Ctr, Limb Ctr, Washington, DC 20007 USA.
   [Gurtner, Geoffrey C.] Stanford Univ, Med Ctr, Dept Surg, Stanford, CA 94305 USA.
   [Ehrlich, H. Paul] Penn State Univ, Milton S Hershey Med Ctr, Dept Surg, Div Plast Surg, Hershey, PA 17033 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Pennsylvania Commonwealth System of Higher Education
   (PCSHE); University of Pittsburgh; Yale University; University of
   Illinois System; University of Chicago; University of Chicago Medical
   Center; Georgetown University; Stanford University; Pennsylvania
   Commonwealth System of Higher Education (PCSHE); Pennsylvania State
   University; Penn State Health
RP Orgill, DP (通讯作者)，Brigham & Womens Hosp, Div Plast & Reconstruct Surg, 75 Francis St, Boston, MA 02115 USA.
EM dorgill@partners.org
RI Orgill, Dennis/H-7596-2019; Lee, Raphael C/KIE-5231-2024
OI Orgill, Dennis/0000-0002-8279-7310; Lee, Raphael C/0000-0002-6628-1867
FU Kinetic Concepts, Inc. (KCI)
FX Supported by a grant from Kinetic Concepts, Inc. (KCI). This document
   reflects the opinion of the authors and was not influenced by KCI.
CR [Anonymous], LAW BONE REMODELING
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NR 71
TC 210
Z9 253
U1 0
U2 23
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
J9 SURGERY
JI Surgery
PD JUL
PY 2009
VL 146
IS 1
BP 40
EP 51
DI 10.1016/j.surg.2009.02.002
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 464IM
UT WOS:000267498600007
PM 19541009
DA 2026-07-24
ER

PT J
AU Hariri, M
   Maaz, B
   Netfagi, M
   Alawa, J
   Sattouf, A
   Dubies, HA
   Alahmad, J
   Seyitisa, MF
   Godier-Furnemont, A
   Ghali, A
   Ghandour, A
   Abdullah, Z
   Alsaleh, M
   Almousa, I
   Habib, W
   Alshaer, H
AF Hariri, Mahmoud
   Maaz, Bakry
   Netfagi, Measser
   Alawa, Jude
   Sattouf, Ahmad
   Dubies, Hussam Alden
   Alahmad, Jehad
   Seyitisa, Muhammet Fuat
   Godier-Furnemont, Amandine
   Ghali, Abedalkarem
   Ghandour, Ahmad
   Abdullah, Zohair
   Alsaleh, Munther
   Almousa, Ibrahim
   Habib, Waiel
   Alshaer, Hisham
TI Validation of a Manual Negative Pressure Wound Therapy Device
   (PragmaVAC) for Acute and Chronic Wounds: A Prospective, Randomized,
   Controlled Trial (September, 10.1007/s00268-022-06713-8, 2022)
SO WORLD JOURNAL OF SURGERY
LA English
DT Correction
C1 [Hariri, Mahmoud; Seyitisa, Muhammet Fuat; Alshaer, Hisham] Pragmat Innovat Inc, Mississauga, ON, Canada.
   [Hariri, Mahmoud; Alahmad, Jehad] Syrian Board Med Specialties SBOMS, Gaziantep, Turkey.
   [Maaz, Bakry; Ghali, Abedalkarem; Alsaleh, Munther] Mohamed Waseem Maaz Hosp, Northern Aleppo, Syria.
   [Netfagi, Measser; Ghandour, Ahmad; Abdullah, Zohair] Rahma Darkoush Hosp, Darkoush, Syria.
   [Alawa, Jude] Stanford Univ, Sch Med, Stanford, CA USA.
   [Dubies, Hussam Alden; Alahmad, Jehad; Almousa, Ibrahim] Idleb Surg Hosp, Idleb, Syria.
   [Godier-Furnemont, Amandine] Univ Calif San Francisco, Dept Surg, San Francisco, CA USA.
   [Sattouf, Ahmad; Habib, Waiel] Idleb Cent Hosp, Idleb, Syria.
C3 Stanford University; University of California System; University of
   California San Francisco
RP Hariri, M (通讯作者)，Pragmat Innovat Inc, Mississauga, ON, Canada.; Hariri, M (通讯作者)，Syrian Board Med Specialties SBOMS, Gaziantep, Turkey.
EM m.hariri@sboms.org
RI ; Alawa, Jude/QJX-2484-2026
OI Godier-Furnemont, Amandine/0000-0002-3613-0881; Alawa,
   Jude/0000-0003-3600-4356; 
CR Hariri M, 2022, WORLD J SURG, V46, P2946, DOI 10.1007/s00268-022-06713-8
NR 1
TC 0
Z9 0
U1 1
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD DEC
PY 2022
VL 46
IS 12
BP 2954
EP 2954
DI 10.1007/s00268-022-06785-6
EA OCT 2022
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 5Y1GG
UT WOS:000869621100001
PM 36255479
OA Bronze
DA 2026-07-24
ER

PT J
AU Wolf, CA
   Coleman, TA
   Wilson, JL
   Hughes, S
AF Wolf, Carol A.
   Coleman, Taylor A.
   Wilson, J. Leigh
   Hughes, Stacy
TI Reduction of Surgical Site Infections in Cesareans Through
   Implementation of Negative Pressure Dressings
SO JOGNN-JOURNAL OF OBSTETRIC GYNECOLOGIC AND NEONATAL NURSING
LA English
DT Meeting Abstract
DE negative pressure wound therapy; HAIs; surgical site infections; silver
   dressings; prevention of surgical site infections
C1 [Wolf, Carol A.; Coleman, Taylor A.; Wilson, J. Leigh; Hughes, Stacy] Texas Hlth Resources Harris Methodist Hurst Eules, Bedford, TX USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0884-2175
EI 1552-6909
J9 JOGNN-J OBST GYN NEO
JI JOGNN
PD JUN
PY 2017
VL 46
IS 3
SU S
BP S15
EP S15
DI 10.1016/j.jogn.2017.04.025
PG 1
WC Nursing; Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing; Obstetrics & Gynecology
GA GG0HI
UT WOS:000432358700030
OA Bronze
DA 2026-07-24
ER

PT J
AU Kairinos, N
   Hudson, DA
   Solomons, MW
AF Kairinos, Nicolas
   Hudson, Donald Anthony
   Solomons, Michael Wayne
TI Comment on "Novel imaging methods reveal positive impact of topical
   negative pressure application on tissue perfusion in an in vivo skin
   model"
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Letter
ID VACUUM-ASSISTED CLOSURE; WOUND THERAPY
C1 [Kairinos, Nicolas; Hudson, Donald Anthony; Solomons, Michael Wayne] Univ Cape Town, Dept Plast & Reconstruct Surg, Cape Town, South Africa.
C3 University of Cape Town
RP Kairinos, N (通讯作者)，Century Med Suites, 4 Pk Lane, ZA-7441 Cape Town, South Africa.
EM nickykairinos@gmail.com
OI Kairinos, Nicolas/0000-0001-9944-2033
CR Biermann N, 2020, J TISSUE VIABILITY, V29, P32, DOI 10.1016/j.jtv.2019.12.004
   Grahn DA, 2005, J APPL PHYSIOL, V99, P972, DOI 10.1152/japplphysiol.00093.2005
   Kairinos N., 2011, BIOMECHANICS NEGATIV
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   Kairinos N, 2010, J PLAST RECONSTR AES, V63, P174, DOI 10.1016/j.bjps.2008.08.037
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P601, DOI 10.1097/PRS.0b013e318196b97b
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P589, DOI 10.1097/PRS.0b013e3181956551
   Macionis V, 2023, INT J LOW EXTR WOUND, V22, P625, DOI 10.1177/15347346211024566
   Maier D, 2005, ZBL CHIR, V130, P463, DOI 10.1055/s-2005-836850
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Muller-Seubert W, 2021, INT WOUND J, V18, P932, DOI 10.1111/iwj.13639
   Sogorski A, 2019, J TISSUE VIABILITY, V28, P48, DOI 10.1016/j.jtv.2018.10.003
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
   Zwanenburg PR, 2019, J TISSUE VIABILITY, V28, P46, DOI 10.1016/j.jtv.2018.10.002
NR 15
TC 0
Z9 0
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2021
VL 18
IS 6
BP 940
EP 941
DI 10.1111/iwj.13677
EA SEP 2021
PG 2
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA XM0ZU
UT WOS:000693772800001
PM 34498372
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Frear, CC
   Cuttle, L
   McPhail, SM
   Chatfield, MD
   Kimble, R
   Griffin, BR
AF Frear, Cody C.
   Cuttle, Leila
   McPhail, Steven M.
   Chatfield, Mark D.
   Kimble, Roy
   Griffin, Bronwyn R.
TI Author response to: Comment on: "Randomized clinical trial of negative
   pressure wound therapy as an adjunctive treatment for small-area thermal
   burns in children" by Frear et al.
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Letter
C1 [Frear, Cody C.; Cuttle, Leila; Kimble, Roy; Griffin, Bronwyn R.] Ctr Childrens Hlth Res, Ctr Childrens Burns & Trauma Res, South Brisbane, Australia.
   [Frear, Cody C.; Chatfield, Mark D.; Kimble, Roy] Univ Queensland, Fac Med, Herston, Qld, Australia.
   [Cuttle, Leila] Queensland Univ Technol, Fac Hlth, Sch Biomed Sci, Brisbane, Qld, Australia.
   [McPhail, Steven M.] Australian Ctr Hlth Serv Innovat, Brisbane, Qld, Australia.
   [McPhail, Steven M.] Fac Hlth, Sch Publ Hlth & Social Work, Ctr Healthcare Transformat, Brisbane, Qld, Australia.
   [McPhail, Steven M.] Metro South Hlth, Clin Informat Directorate, Brisbane, Qld, Australia.
   [Kimble, Roy] Queensland Childrens Hosp, South Brisbane, Australia.
   [Griffin, Bronwyn R.] Queensland Univ Technol, Fac Hlth, Sch Nursing, Brisbane, Qld, Australia.
C3 University of Queensland; Queensland University of Technology (QUT);
   Childrens Health Queensland Hospital & Health Service; Queensland
   Childrens Hospital; Queensland University of Technology (QUT)
RP Frear, CC (通讯作者)，Univ Queensland, Childrens Hlth Res Ctr, Ctr Childrens Burns & Trauma Res, Level 7,62 Graham St, South Brisbane, Qld 4101, Australia.
EM cody.frear@uqconnect.edu.au
RI ; Chatfield, Mark/N-2278-2013; Griffin, Bronwyn/AEB-6299-2022; Cuttle,
   Leila/C-5223-2008; McPhail, Steven/JMR-2141-2023; Kimble,
   Roy/B-4160-2011
OI Frear, Cody/0000-0002-6011-2472; Chatfield, Mark/0000-0002-0004-6274;
   Griffin, Bronwyn/0000-0002-6182-9125; Cuttle, Leila/0000-0002-2282-4815;
   McPhail, Steven/0000-0002-1463-662X; 
FU Smith Nephew
FX Smith & Nephew provided funding for the original study in the form of a
   research grant, but had no role in the design of the trial, data
   collection, analysis, decision to publish, drafting and revision of the
   trial manuscript, or preparation of this response.
CR Frear CC, 2020, BJS-BRIT J SURG, V107, P1741, DOI 10.1002/bjs.11993
NR 1
TC 0
Z9 0
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD FEB
PY 2021
VL 108
IS 2
BP E87
EP E87
DI 10.1093/bjs/znaa078
EA JAN 2021
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA RI6NP
UT WOS:000637024200018
PM 33711134
OA Bronze
DA 2026-07-24
ER

PT J
AU Costa, ML
   Achten, J
   Knight, R
   Png, ME
   Bruce, J
   Dutton, S
   Madan, J
   Vadher, K
   Dritsaki, M
   Masters, J
   Spoors, L
   Campolier, M
   Parsons, N
   Fernandez, M
   Jones, S
   Grant, R
   Nanchahal, J
AF Costa, Matthew L.
   Achten, Juul
   Knight, Ruth
   Png, May Ee
   Bruce, Julie
   Dutton, Susan
   Madan, Jason
   Vadher, Karan
   Dritsaki, Melina
   Masters, James
   Spoors, Louise
   Campolier, Marta
   Parsons, Nick
   Fernandez, Miguel
   Jones, Suzanne
   Grant, Richard
   Nanchahal, Jagdeep
CA WhiST Collaborators
TI Negative-pressure wound therapy compared with standard dressings
   following surgical treatment of major trauma to the lower limb: the
   WHiST RCT
SO HEALTH TECHNOLOGY ASSESSMENT
LA English
DT Article
ID TIBIAL PLAFOND; OPEN FRACTURE; HEALTH; DISABILITY; FIXATION; EQ-5D-5L;
   PATIENT; ADULTS; PAIN
AB Background: Major trauma is the leading cause of death in people aged < 45 years. Patients with major trauma usually have lower-limb fractures. Surgery to fix the fractures is complicated and the risk of infection may be as high as 27%. The type of dressing applied after surgery could potentially reduce the risk of infection.
   Objectives: To assess the deep surgical site infection rate, disability, quality of life, patient assessment of the surgical scar and resource use in patients with surgical incisions associated with fractures following major trauma to the lower limbs treated with incisional negative-pressure wound therapy versus standard dressings.
   Design: A pragmatic, multicentre, randomised controlled trial.
   Setting: Twenty-four specialist trauma hospitals representing the UK Major Trauma Network.
   Participants: A total of 1548 adult patients were randomised from September 2016 to April 2018. Exclusion criteria included presentation > 72 hours after injury and inability to complete questionnaires.
   Interventions: Incisional negative-pressure wound therapy (n = 785), in which a non-adherent absorbent dressing covered with a semipermeable membrane is connected to a pump to create a partial vacuum over the wound, versus standard dressings not involving negative pressure (n = 763). Trial participants and the treating surgeon could not be blinded to treatment allocation.
   Main outcome measures: Deep surgical site infection at 30 days was the primary outcome measure. Secondary outcomes were deep infection at 90 days, the results of the Disability Rating Index, health-related quality of life, the results of the Patient and Observer Scar Assessment Scale and resource use collected at 3 and 6 months post surgery.
   Results: A total of 98% of participants provided primary outcome data. There was no evidence of a difference in the rate of deep surgical site infection at 30 days. The infection rate was 6.7% (50/749) in the standard dressing group and 5.8% (45/770) in the incisional negative-pressure wound therapy group (intention-to-treat odds ratio 0.87; 95% confidence interval 0.57 to 1.33; p = 0.52). There was no difference in the deep surgical site infection rate at 90 days: 13.2% in the standard dressing group and 11.4% in the incisional negative-pressure wound therapy group (odds ratio 0.84, 95% confidence interval 0.59 to 1.19; p = 0.32). There was no difference between the two groups in disability, quality of life or scar appearance at 3 or 6 months. Incisional negative-pressure wound therapy did not reduce the cost of treatment and was associated with a low probability of cost-effectiveness.
   Limitations: Owing to the emergency nature of the surgery, we anticipated that some patients who were randomised would subsequently be unable or unwilling to participate. However, the majority of the patients (85%) agreed to participate. Therefore, participants were representative of the population with lower-limb fractures associated with major trauma.
   Conclusions: The findings of this study do not support the use of negative-pressure wound therapy in patients having surgery for major trauma to the lower limbs.
   Future work: Our work suggests that the use of incisional negative-pressure wound therapy dressings in other at-risk surgical wounds requires further investigation. Future research may also investigate different approaches to reduce postoperative infections, for example the use of topical antibiotic preparations in surgical wounds and the role of orthopaedic implants with antimicrobial coatings when fixing the associated fracture.
C1 [Costa, Matthew L.; Achten, Juul; Masters, James; Spoors, Louise; Campolier, Marta; Fernandez, Miguel; Nanchahal, Jagdeep] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford Trauma, Oxford, England.
   [Knight, Ruth; Png, May Ee; Dutton, Susan; Vadher, Karan; Dritsaki, Melina] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford Clin Trials Res Unit, Oxford, England.
   [Bruce, Julie; Madan, Jason] Univ Warwick, Warwick Med Sch, Clin Trials Unit, Coventry, W Midlands, England.
   [Parsons, Nick] Univ Warwick, Warwick Med Sch, Stat & Epidemiol Unit, Coventry, W Midlands, England.
C3 University of Oxford; University of Oxford; University of Warwick;
   University of Warwick
RP Costa, ML (通讯作者)，Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford Trauma, Oxford, England.
EM matthew.costa@ndorms.ox.ac.uk
RI ; Masters, James/U-8764-2019; Achten, Juul/KUD-8515-2024; Bruce,
   Julie/G-7588-2014; Parsons, Nick/AAA-8713-2019; Png, May
   Ee/AAG-4902-2019
OI Madan, Jason/0000-0003-4316-1480; Masters, James/0000-0001-9663-8858;
   Achten, Juul/0000-0002-8857-5743; Costa, Matthew/0000-0003-3644-1388;
   Bruce, Julie/0000-0002-8462-7999; Parsons, Nick/0000-0001-9975-888X;
   Knight, Ruth/0000-0001-6810-2845; Nanchahal,
   Jagdeep/0000-0002-9579-9411; Png, May Ee/0000-0001-5876-9363; Campolier,
   Marta/0000-0002-7168-2534; Vadher, Karan/0000-0002-6287-5596
FU National Institute for Health Research Health Technology Assessment
   programme; National Institute for Health Research [14/199/14] Funding
   Source: researchfish
FX This project was funded by the National Institute for Health Research
   Health Technology Assessment programme and will be published in full in
   Health Technology Assessment; Vol. 24, No. 38. See the NIHR Journals
   Library for further project information.
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NR 62
TC 17
Z9 20
U1 0
U2 9
PU NIHR JOURNALS LIBRARY
PI SOUTHAMPTON
PA UNIV SOUTHAMPTON, EVALUATION, TRIALS & STUDIES COORDINATING CENTRE,
   ALPHA HOUSE, ENTERPRISE RD, SOUTHAMPTON, SO16 7NS, ENGLAND
SN 1366-5278
EI 2046-4924
J9 HEALTH TECHNOL ASSES
JI Health Technol. Assess.
PD AUG
PY 2020
VL 24
IS 38
BP I
EP +
DI 10.3310/hta24380
PG 108
WC Health Care Sciences & Services
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services
GA NF0MJ
UT WOS:000562997400001
PM 32821038
OA Green Submitted, gold
DA 2026-07-24
ER

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SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
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DT Meeting Abstract
ID INFECTION
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U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
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J9 J WOUND OSTOMY CONT
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PY 2024
VL 51
IS 3
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EP S77
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WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA C6T5F
UT WOS:001290677800163
DA 2026-07-24
ER

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TI Response to Letter to the Editor: The impact of negative pressure wound
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   A systematic review and meta-analysis
SO SURGERY
LA English
DT Letter
C1 [Shiroky, Jonah; Karanicolas, Paul J.] Sunnybrook Hlth Sci Ctr, Div Gen Surg, Toronto, ON, Canada.
   [Lillie, Erin; Karanicolas, Paul J.] Sunnybrook Hlth Sci Ctr, Sunnybrook Res Inst, Toronto, ON, Canada.
   [Muaddi, Hala; Sevigny, Marika; Choi, Woo Jin; Karanicolas, Paul J.] Univ Toronto, Dept Surg, Div Gen Surg, Toronto, ON, Canada.
   [Karanicolas, Paul J.] Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada.
C3 University of Toronto; Sunnybrook Research Institute; Sunnybrook Health
   Science Center; University of Toronto; Sunnybrook Health Science Center;
   Sunnybrook Research Institute; University of Toronto; University of
   Toronto
RP Karanicolas, PJ (通讯作者)，Sunnybrook Hlth Sci Ctr, Div Gen Surg, Toronto, ON, Canada.; Karanicolas, PJ (通讯作者)，Sunnybrook Hlth Sci Ctr, Sunnybrook Res Inst, Toronto, ON, Canada.; Karanicolas, PJ (通讯作者)，Univ Toronto, Dept Surg, Div Gen Surg, Toronto, ON, Canada.; Karanicolas, PJ (通讯作者)，Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada.
EM paul.karanicolas@sunnybrook.ca
RI Muaddi, Hala/AAE-1264-2021
OI Shiroky, Jonah/0000-0003-1113-9676
NR 0
TC 2
Z9 2
U1 0
U2 1
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
EI 1532-7361
J9 SURGERY
JI Surgery
PD MAY
PY 2021
VL 169
IS 5
BP 1259
EP 1259
DI 10.1016/j.surg.2020.10.005
EA MAY 2021
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA RY1PQ
UT WOS:000647689600051
PM 33172622
DA 2026-07-24
ER

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   Therapy System on Wound Complications and Surgical Site Infections in
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SO AMERICAN JOURNAL OF TRANSPLANTATION
LA English
DT Meeting Abstract
CT American Transplant Congress (ATC)
CY MAY 30-JUN 01, 2020
CL ELECTR NETWORK
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C3 NSW Health; Royal Prince Alfred Hospital; University of Sydney
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PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1600-6135
EI 1600-6143
J9 AM J TRANSPLANT
JI Am. J. Transplant.
PD APR
PY 2020
VL 20
SU 3
SI SI
MA A-99
BP 603
EP 603
PG 1
WC Surgery; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery; Transplantation
GA MH3JZ
UT WOS:000546629502163
DA 2026-07-24
ER

PT J
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SO INTERNATIONAL WOUND JOURNAL
LA English
DT Correction
C1 [Morais, Liliana Patricia Ferreira; Moore, Zena Elizabeth Helen; Patton, Declan; O' Connor, Tom; Avsar, Pinar; Wilson, Hannah Jane Elizabeth] Univ Med & Hlth Sci, Royal Coll Surg Ireland RCSI, Dublin, Ireland.
   [Morais, Liliana Patricia Ferreira; Moore, Zena Elizabeth Helen; Patton, Declan; O' Connor, Tom; Avsar, Pinar; Wilson, Hannah Jane Elizabeth] RCSI Univ Med & Hlth Sci, Sch Nursing & Midwifery, Dublin, Ireland.
   [Moore, Zena Elizabeth Helen; Patton, Declan; O' Connor, Tom; Avsar, Pinar; Wilson, Hannah Jane Elizabeth] RCSI Univ Med & Hlth Sci, Skin Wounds & Trauma Res Ctr, Dublin, Ireland.
   [Moore, Zena Elizabeth Helen; Patton, Declan; O' Connor, Tom] Fakeeh Coll Hlth Sci, Jeddah, Saudi Arabia.
   [Moore, Zena Elizabeth Helen; Patton, Declan; O' Connor, Tom] Griffith Univ, Sch Nursing & Midwifery, Brisbane, Qld, Australia.
   [Moore, Zena Elizabeth Helen] Univ Ghent, Fac Med & Hlth Sci, Dept Publ Hlth, Shanghai, Peoples R China.
   [Moore, Zena Elizabeth Helen] Menzies Hlth Inst, Natl Hlth & Med Res Council Ctr Res Excellence Wis, Brisbane, Qld, Australia.
   [Moore, Zena Elizabeth Helen] Cardiff Univ, Cardiff, Wales.
   [Patton, Declan] Univ Wollongong, Fac Sci Med & Hlth, Wollongong, NSW, Australia.
   [O' Connor, Tom] Lida Inst, Shanghai, Peoples R China.
C3 Royal College of Surgeons in Ireland - RCSI; Royal College of Surgeons
   in Ireland - RCSI; Royal College of Surgeons in Ireland - RCSI; Fakeeh
   College for Medical Sciences; Griffith University; Ghent University;
   Menzies Health Institute Queensland; Cardiff University; University of
   Wollongong
RP Morais, LPF (通讯作者)，Univ Med & Hlth Sci, Royal Coll Surg Ireland RCSI, Dublin, Ireland.; Morais, LPF (通讯作者)，RCSI Univ Med & Hlth Sci, Sch Nursing & Midwifery, Dublin, Ireland.
CR Morais LPF, 2025, INT WOUND J, V22, DOI 10.1111/iwj.70194
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TC 0
Z9 0
U1 0
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PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2025
VL 22
IS 6
AR e70696
DI 10.1111/iwj.70696
PG 1
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA F0229
UT WOS:001623124600001
OA Green Submitted, gold
DA 2026-07-24
ER

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SO ANNALS OF SURGICAL ONCOLOGY
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DT Editorial Material
C1 [Moncrieff, Marc; Heaton, Martin] Norfolk & Norwich Univ Hosp, Plast & Reconstruct Surg, Norwich, Norfolk, England.
   [Moncrieff, Marc] Univ East Anglia, Norwich Med Sch, Fac Med & Hlth Sci, Norwich, Norfolk, England.
C3 Norfolk & Norwich University Hospitals NHS Foundation Trust; Norfolk &
   Norwich University Hospital; University of East Anglia
RP Moncrieff, M (通讯作者)，Norfolk & Norwich Univ Hosp, Plast & Reconstruct Surg, Norwich, Norfolk, England.; Moncrieff, M (通讯作者)，Univ East Anglia, Norwich Med Sch, Fac Med & Hlth Sci, Norwich, Norfolk, England.
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U2 1
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J9 ANN SURG ONCOL
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PD OCT
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WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA NJ1JU
UT WOS:000558863800004
PM 32462528
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU McNulty, AK
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SO WOUND REPAIR AND REGENERATION
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DT Meeting Abstract
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TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JUL
PY 2024
VL 32
IS 4
MA P26
BP 567
EP 568
PG 2
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA C6R8X
UT WOS:001290635400145
DA 2026-07-24
ER

PT J
AU Zuckerman, J
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AF Zuckerman, Jesse
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TI Inconclusive trial results regarding prophylactic negative pressure
   wound therapy for major pancreatic surgery: Mitigating publication bias
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SO SURGERY
LA English
DT Editorial Material
ID SURGICAL SITE INFECTION; POSTOPERATIVE COMPLICATIONS; IMPACT
C1 [Zuckerman, Jesse; Hallet, Julie] Univ Toronto, Dept Surg, Div Gen Surg, Toronto, ON, Canada.
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C3 University of Toronto; University of Toronto; University of Toronto;
   Sunnybrook Health Science Center; Sunnybrook Research Institute;
   University of Toronto; Sunnybrook Health Science Center; Sunnybrook
   Research Institute
RP Zuckerman, J (通讯作者)，Univ Toronto, Dept Surg, Div Gen Surg, Toronto, ON, Canada.; Zuckerman, J (通讯作者)，Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada.
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NR 15
TC 1
Z9 1
U1 0
U2 0
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
EI 1532-7361
J9 SURGERY
JI Surgery
PD MAY
PY 2021
VL 169
IS 5
BP 1076
EP 1077
DI 10.1016/j.surg.2020.11.036
EA MAY 2021
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA RY1PQ
UT WOS:000647689600022
PM 33353733
DA 2026-07-24
ER

PT J
AU Sharr, PJ
   Buckley, RE
AF Sharr, P. J.
   Buckley, R. E.
TI Current Concepts Review: Open Tibial Fractures
SO ACTA CHIRURGIAE ORTHOPAEDICAE ET TRAUMATOLOGIAE CECHOSLOVACA
LA English
DT Review
ID PRESSURE WOUND THERAPY; VACUUM-ASSISTED CLOSURE; OPEN EXTREMITY
   FRACTURES; SOFT-TISSUE COVERAGE; ANTIBIOTIC-PROPHYLAXIS; SURGICAL
   DEBRIDEMENT; INFECTION-RATE; BONE; CLASSIFICATION; EPIDEMIOLOGY
C1 [Sharr, P. J.; Buckley, R. E.] Univ Calgary, Foothills Med Ctr, Dept Orthopaed Surg, Calgary, AB T2N 1N4, Canada.
C3 University of Calgary; University Calgary Hospital
RP Buckley, RE (通讯作者)，Univ Calgary, Foothills Med Ctr, Dept Orthopaed Surg, Calgary, AB T2N 1N4, Canada.
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NR 105
TC 5
Z9 8
U1 0
U2 6
PU GALEN SRO
PI PRAGUE 5
PA NA BELIDLE 34, PRAGUE 5, 150 00, CZECH REPUBLIC
SN 0001-5415
J9 ACTA CHIR ORTHOP TR
JI Acta Chir. Orthop. Traumatol. Cechoslov.
PD APR
PY 2014
VL 81
IS 2
BP 95
EP 107
PG 13
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA AG4DG
UT WOS:000335368900001
PM 25105791
DA 2026-07-24
ER

PT J
AU Fox, CM
   Johnson, B
   Storey, K
   Das Gupta, R
   Kimble, R
AF Fox, Carly M.
   Johnson, Bethan
   Storey, Kristen
   Das Gupta, Romi
   Kimble, Roy
TI Negative pressure wound therapy in the treatment of ulcerated infantile
   haemangioma
SO PEDIATRIC SURGERY INTERNATIONAL
LA English
DT Article
DE Negative pressure wound therapy; Infantile haemangioma; Vascular
   malformations; Wound healing
ID SUBATMOSPHERIC PRESSURE; PREVENTION; PROPRANOLOL; MULTICENTER;
   MANAGEMENT; INFECTION
AB Infantile haemangioma is a common benign tumour of infancy. Ulceration is the most common complication and is often painful and difficult to treat. Propranolol therapy is widely used to induce involution in rapidly growing or ulcerated lesions, or those in anatomically awkward locations. The ideal dressing regimen for these lesions would provide effective analgesia, act as a wound dressing, and aid involution of the primary lesion. To date, no ideal regimen has been established. Negative pressure wound therapy (NPWT) has been used in adult and paediatric populations to help improve wound healing in a variety of settings. It may provide a useful alternative to traditional dressing regimens in ulcerated infantile haemangioma.
   Six consecutive patients with ulcerating infantile haemangioma presenting to the Royal Children's Hospital vascular anomalies clinic were included in the study. Each patient was treated with a combination of NPWT and propranolol. Outcomes including time to wound healing, perceived ease of dressing management, and analgesia were recorded.
   Complete wound healing was obtained in all cases. Patient outcomes in terms of analgesia, comfort, and ease of wound dressing were improved following application of NPWT.
   We propose that this regimen represents a novel therapy for management of ulcerated infantile haemangioma. Possible mechanisms for healing effect, and improved analgesia are discussed. Further investigation is required to determine if negative pressure wound therapy results in faster healing times compared to traditional dressing regimens.
C1 [Fox, Carly M.; Johnson, Bethan; Storey, Kristen; Das Gupta, Romi; Kimble, Roy] Lady Cilento Childrens Hosp, Dept Paediat & Child Hlth, Vasc Anomalies Grp, Royal Childrens Hosp, South Brisbane, Qld 4101, Australia.
   [Johnson, Bethan; Storey, Kristen; Das Gupta, Romi; Kimble, Roy] Univ Queensland, Lady Cilento Childrens Hosp, Dept Paediat Surg, South Brisbane, Qld 4101, Australia.
   [Fox, Carly M.] Lady Cilento Childrens Hosp, Dept Plast & Reconstruct Surg, South Brisbane, Qld 4101, Australia.
C3 Childrens Health Queensland Hospital & Health Service; Queensland
   Childrens Hospital; University of Queensland; Childrens Health
   Queensland Hospital & Health Service; Queensland Childrens Hospital;
   Childrens Health Queensland Hospital & Health Service; Queensland
   Childrens Hospital
RP Fox, CM (通讯作者)，Lady Cilento Childrens Hosp, Dept Paediat & Child Hlth, Vasc Anomalies Grp, Royal Childrens Hosp, South Brisbane, Qld 4101, Australia.
EM carlymfox@gmail.com
RI Kimble, Roy/B-4160-2011
OI Kimble, Roy/0000-0002-2449-7707
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NR 25
TC 11
Z9 12
U1 0
U2 6
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0179-0358
EI 1437-9813
J9 PEDIATR SURG INT
JI Pediatr. Surg. Int.
PD JUL
PY 2015
VL 31
IS 7
BP 653
EP 658
DI 10.1007/s00383-015-3716-x
PG 6
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA CK0ZI
UT WOS:000355934000008
PM 25966985
DA 2026-07-24
ER

PT J
AU Keskin, M
   Bayram, O
   Bulut, T
   Balik, E
AF Keskin, Metin
   Bayram, Onur
   Bulut, Turker
   Balik, Emre
TI Effectiveness of Endoluminal Vacuum-assisted Closure Therapy
   (Endosponge) for the Treatment of Pelvic Anastomotic Leakage After
   Colorectal Surgery
SO SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES
LA English
DT Article
ID ENDO-SPONGE TREATMENT; ANTERIOR RESECTION; WOUND CONTROL; EXPERIENCE;
   RECTUM
C1 [Keskin, Metin; Bayram, Onur; Bulut, Turker] Istanbul Univ, Sch Med, Dept Gen Surg, Istanbul, Turkey.
   [Balik, Emre] Koc Univ, Dept Gen Surg, Sch Med, TR-34450 Istanbul, Turkey.
C3 Istanbul University; Koc University
RP Balik, E (通讯作者)，Koc Univ, Dept Gen Surg, Sch Med, TR-34450 Istanbul, Turkey.
EM ebalik@ku.edu.tr
RI BALIK, Emre/C-2438-2014; Bulut, Mehmet/AAY-6153-2020; Keskin,
   Metin/AAY-8567-2020
OI BALIK, Emre/0000-0001-5751-1133; 
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NR 17
TC 24
Z9 27
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1530-4515
EI 1534-4908
J9 SURG LAPARO ENDO PER
JI Surg. Laparosc. Endosc. Pct. Tech.
PD DEC
PY 2015
VL 25
IS 6
BP 505
EP 508
DI 10.1097/SLE.0000000000000216
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CY8XR
UT WOS:000366692500010
PM 26551234
DA 2026-07-24
ER

PT J
AU Morais, LPF
   Moore, ZEH
   Patton, D
   Connor, TO
   Wilson, HJE
AF Morais, Liliana Patricia Ferreira
   Moore, Zena Elizabeth Helen
   Patton, Declan
   Connor, Tom O'
   Wilson, Hannah Jane Elizabeth
TI What is the Impact of Negative Pressure Wound Therapy on Healing in
   Patients Post Excision of Pilonidal Sinus? A Systematic Review and
   Meta-Analysis
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Review
DE negative pressure wound therapy; NPWT; pilonidal cyst; pilonidal sinus;
   systematic review
ID SURGERY; DISEASE
AB This systematic review aimed to determine the impact of negative pressure wound therapy on healing in patients with pilonidal sinus following surgical excision. Using systematic review methodology, we included original research studies written in English. The search was conducted using CINAHL Plus, Ovid, PubMed, EBSCO Host and Cochrane databases. Quality appraisal was undertaken using the Cochrane Collaboration tool for assessing risk of bias and the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Data were analysed using meta-analysis where appropriate; otherwise, the data are presented narratively. Ten studies were included with a mean sample size of 61 (SD: 33). Three studies were randomised control trials, four were retrospective studies, two were prospective cohort studies and one was pre-post study. Studies showed reduction in healing time, recurrence rates and postoperative pain, as well as higher patients' satisfaction with the use negative pressure wound therapy, however, the certainty of the evidence was very low. The evidence for the intervention is uncertain thus, it is unclear whether NPWT makes any difference when compared to any other dressings, on time to healing, recurrence, pain or patient's experience. Further high-quality research with larger sample sizes is recommended to clearly explore the impact of NPWT on PS healing, recurrence, pain and patient's satisfaction.
C1 [Morais, Liliana Patricia Ferreira; Moore, Zena Elizabeth Helen; Patton, Declan; Connor, Tom O'; Wilson, Hannah Jane Elizabeth] Univ Med & Hlth Sci, Royal Coll Surg Ireland RCSI, Dublin, Ireland.
   [Morais, Liliana Patricia Ferreira; Moore, Zena Elizabeth Helen; Patton, Declan; Connor, Tom O'; Wilson, Hannah Jane Elizabeth] RCSI Univ Med & Hlth Sci, Sch Nursing & Midwifery, Dublin, Ireland.
   [Moore, Zena Elizabeth Helen; Patton, Declan; Connor, Tom O'; Wilson, Hannah Jane Elizabeth] RCSI Univ Med & Hlth Sci, Skin Wounds & Trauma Res Ctr, Dublin, Ireland.
   [Moore, Zena Elizabeth Helen; Patton, Declan; Connor, Tom O'] Fakeeh Coll Med Sci, Jeddah, Saudi Arabia.
   [Moore, Zena Elizabeth Helen; Connor, Tom O'] Griffith Univ, Sch Nursing & Midwifery, Brisbane, Qld, Australia.
   [Moore, Zena Elizabeth Helen; Connor, Tom O'] Lida Inst, Shanghai, Peoples R China.
   [Moore, Zena Elizabeth Helen] Monash Univ, Fac Med Nursing & Hlth Sci, Melbourne, Vic, Australia.
   [Moore, Zena Elizabeth Helen] Univ Ghent, Fac Med & Hlth Sci, Dept Publ Hlth, Shanghai, Peoples R China.
   [Moore, Zena Elizabeth Helen] Univ Wales Coll Cardiff, Cardiff, Wales.
   [Moore, Zena Elizabeth Helen] Natl Hlth & Med Res Council Ctr Res Excellence Wis, Menzies Hlth Inst Queensland, Brisbane, Qld, Australia.
   [Patton, Declan] Univ Wollongong, Fac Sci Med & Hlth, Wollongong, NSW, Australia.
C3 Royal College of Surgeons in Ireland - RCSI; Royal College of Surgeons
   in Ireland - RCSI; Royal College of Surgeons in Ireland - RCSI; Fakeeh
   College for Medical Sciences; Griffith University; Monash University;
   Ghent University; Cardiff University; Menzies Health Institute
   Queensland; University of Wollongong
RP Morais, LPF (通讯作者)，Univ Med & Hlth Sci, Royal Coll Surg Ireland RCSI, Dublin, Ireland.; Morais, LPF (通讯作者)，RCSI Univ Med & Hlth Sci, Sch Nursing & Midwifery, Dublin, Ireland.
EM lilianamorais21@rcsi.com; zmoore@rcsi.com; declanpatton@rcsi.com;
   tomoconnor@rcsi.ie; wilsonhannah@rcsi.com
OI Patricia Ferreira Morais, Liliana/0009-0007-8750-9393
CR El-Tohfa YAY, 2020, Al-Azhar Medical Journal, V49, P1303, DOI 10.21608/amj.2020.107126
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   Zaver V., 2025, StatPearls [Internet]
NR 40
TC 2
Z9 2
U1 2
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAY
PY 2025
VL 22
IS 5
AR e70194
DI 10.1111/iwj.70194
PG 12
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA F0169
UT WOS:001623118600001
PM 40288765
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Accurso, A
   Rocco, N
   Accardo, G
   Reale, P
   Salerno, C
   Mattera, E
   D'Andrea, F
AF Accurso, Antonello
   Rocco, Nicola
   Accardo, Giuseppe
   Reale, Paola
   Salerno, Carmela
   Mattera, Edi
   D'Andrea, Francesco
TI Innovative Management of Implant Exposure in ADM/Implant-Based Breast
   Reconstruction with Negative Pressure Wound Therapy
SO AESTHETIC PLASTIC SURGERY
LA English
DT Article
DE Breast reconstruction; A cellular dermal matrix; Negative pressure wound
   therapy; Implant exposure
ID ACELLULAR DERMAL MATRIX; SURGERY; ALLODERM; MESH
AB One-stage implant-based breast reconstruction has been recently improved by the introduction of biological [acellular dermal matrix (ADM)] and synthetic meshes. Advantages of ADMs in implant-based breast reconstruction derive from the expansion of the space available for the direct positioning of an implant, but their use could be associated with several complications. Although the majority of complications can be easily managed, mistakes in dealing with the first clinical signs of a potential adverse event can lead to implant loss.
   We report a case of ADM/implant exposure following NAC-sparing mastectomy and immediate implant-based reconstruction, successfully managed with an innovative staged treatment using negative pressure wound therapy, which allowed a rapid re-positioning of the prosthesis after complete clearance of bacteria from the implant pocket.
   The safest strategy to manage implant exposure and concomitant bacterial growth is reported to be implant removal and delayed re-positioning after several months, following prolonged targeted antibiotic therapy. Our case shows how a short-time implant re-positioning following implant removal for implant exposure could be successfully pursued thanks to the shrewd use of negative pressure wound therapy with great advantages in terms of patient satisfaction and post-operative quality of life, offering women experiencing this complication the option of not delaying reconstruction for months after resolution of the complication, potentially avoiding major surgical procedures such as autologous tissue reconstructions.
C1 [Accurso, Antonello; Accardo, Giuseppe; Reale, Paola; Salerno, Carmela] Univ Hosp Federico II, Dept Surg, Breast Unit, Naples, Italy.
   [Rocco, Nicola] Univ Naples Federico II, Dept Clin Med & Surg, Via S Pansini 5, I-80131 Naples, Italy.
   [Mattera, Edi] Univ Naples 2, Dept Clin & Expt Med Flaviano Magrassi, Clin Med Hosp Unit, Ambulatory Vulnol, Naples, Italy.
   [D'Andrea, Francesco] Univ Naples Federico II, Dept Plast & Reconstruct Surg, Naples, Italy.
C3 University of Naples Federico II; Universita della Campania Vanvitelli;
   University of Naples Federico II
RP Rocco, N (通讯作者)，Univ Naples Federico II, Dept Clin Med & Surg, Via S Pansini 5, I-80131 Naples, Italy.
EM nicolarocco2003@gmail.com
OI Rocco, Nicola/0000-0001-6941-7873
CR Becker S, 2009, PLAST RECONSTR SURG, V123, P1, DOI 10.1097/PRS.0b013e3181904bff
   Citron I, 2016, GMS INTERDISCIP PLAS, V5, DOI 10.3205/iprs000085
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NR 11
TC 17
Z9 19
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0364-216X
EI 1432-5241
J9 AESTHET PLAST SURG
JI Aesthet. Plast. Surg.
PD FEB
PY 2017
VL 41
IS 1
BP 36
EP 39
DI 10.1007/s00266-016-0739-1
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EL2DL
UT WOS:000394430200006
PM 28032164
DA 2026-07-24
ER

PT J
AU Waddell, L
AF Waddell, Lindsey
TI EVALUATION OF NEGATIVE PRESSURE WOUND THERAPY WITH INSTILLATION AND A
   NOVEL RETICULATED OPEN CELL FOAM INSTILLATION DRESSING WITH THROUGH
   HOLES AT A WOUND CARE CENTER: A CASE SERIES
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
EM lindsey@integumetrix.com
CR Brinkert D, 2013, INT WOUND J, V10, P56, DOI 10.1111/iwj.12176
   Gabriel Allen, 2014, Eplasty, V14, pe41
   Kim PJ, 2015, PLAST RECONSTR SURG, V136, p657E, DOI 10.1097/PRS.0000000000001709
   Téot L, 2017, INT WOUND J, V14, P842, DOI 10.1111/iwj.12719
NR 4
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2018
VL 45
SU 3
MA CS45
BP S21
EP S22
PG 2
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA VJ3IV
UT WOS:000579808400051
DA 2026-07-24
ER

PT J
AU Zhang, XL
   Chen, YJ
   Xiao, XD
   Wang, Z
   Yang, X
   Zhao, ZM
AF Zhang, Xinling
   Chen, Yujie
   Xiao, Xiaodi
   Wang, Zheng
   Yang, Xin
   Zhao, Zhenmin
TI 被撤回的出版物: Application of VSD technique in adults with chronic
   osteomyelitis of the extremities combined with soft tissue defects
   (Retracted article. See vol. 22, 2025)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article; Retracted Publication
DE osteomyelitis; skin grafting; soft tissue defects; vacuum sealing
   drainage (VSD)
AB To investigate the clinical application of vacuum sealing drainage (VSD) in chronic osteomyelitis of the extremities combined with soft tissue defects in adults. This study retrospectively included 32 adult patients with clearly diagnosed chronic osteomyelitis of the extremities combined with local soft tissue defects, and the trauma was covered by VSD after debridement, osteotomy, and vancomycin-laden bone cement filling of the occupancy, and the trauma was covered by selecting a suitable flap transfer repair according to the site and extent of the soft tissue defect after the trauma condition was suitable, and the secondary trauma was taken from the abdominal full-thickness skin free skin slice graft, according to whether the skin graft area was performed. The skin flap hematoma and infection rate, as well as the skin flap survival rate and implant fixation time were compared and analysed between the two groups. The primary outcome is the implant fixation time, and the secondary outcome is the skin fragment survival rate. In 32 patients, VSD was performed on the bone cement surface to cover the trauma, and 33.2 to 39.8 kPa continuous vacuum sealing drainage was set. The average VSD time duration before soft tissue coverage was 47.87 +/- 23.14 days, and the average number of VSD use was 7.18 +/- 3.23. The use of VSD before soft tissue coverage did not cause complications such as negative pressure could not be maintained, vacuum sealing drainage was not smooth, skin blistering, trauma. Among the 32 patients, 12 cases of soft tissue coverage were followed by trauma free skin grafting with packing + VSD, and 20 cases were fixed with packing alone, and the duration of continuous packing and fixation of free skin pieces in the VSD group was significantly less than that in the control group (P = .006). The survival rate was significantly higher than that of the control group (P = .019). VSD in adult patients with chronic osteomyelitis of the extremities combined with soft tissue defects can effectively improve the trauma condition, provide the possibility of second-stage soft tissue coverage, and significantly shorten the preparation time for soft tissue coverage. In addition, when soft tissue coverage trauma is performed, VSD combined with skin graft packing technique can significantly improve the survival rate of skin pieces, shorten the time of skin graft fixation.
C1 [Zhang, Xinling; Chen, Yujie; Xiao, Xiaodi; Wang, Zheng; Yang, Xin; Zhao, Zhenmin] Peking Univ Third Hosp, Dept Plast Surg, 49 North Garden Rd, Beijing 100191, Peoples R China.
C3 Peking University
RP Yang, X; Zhao, ZM (通讯作者)，Peking Univ Third Hosp, Dept Plast Surg, 49 North Garden Rd, Beijing 100191, Peoples R China.
EM yangxin6@126.com; zhaozhenmin0098@vip.sina.com
RI Zhao, Zhenmin/NCV-1162-2025
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NR 18
TC 8
Z9 10
U1 1
U2 14
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAR
PY 2023
VL 20
IS 3
BP 768
EP 773
DI 10.1111/iwj.13921
EA AUG 2022
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 9E2HG
UT WOS:000851451300001
PM 36382601
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Guo, CC
   Cheng, T
   Li, JS
AF Guo, Chenchen
   Cheng, Tao
   Li, Junsheng
TI Prophylactic negative pressure wound therapy on surgical site infection
   in obese women after cesarean section: A systematic review and
   meta-analysis
SO INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
LA English
DT Review
DE cesarean section; negative pressure wound therapy; obesity; surgical
   site infection; wound complications
ID DELIVERY; RISK; TRIAL
AB Prevention of surgical site infection (SSI) is a public health challenge. The objective of the study was to evaluate the efficacy of negative pressure wound therapy (NPWT) for preventing SSI and other wound complications in obese women undergoing cesarean section. The search terms included "negative pressure wound therapy", "obesity" and "cesarean section/delivery". Randomized controlled trials were used to compare the use of NPWT to standard dressings in preventing SSI in obese women after cesarean section. A comprehensive literature search of four databases was performed up to June 2021. The primary outcome was SSI. Secondary outcomes were seroma, hematoma, overall wound complications, and adverse skin reactions. Ten RCTs involving 5586 patients met the inclusion criteria. The use of NPWT reduced SSI (RR = 0.76, 95%CI: 0.63-0.92, P = 0.004). No statistically significant difference was detected in the incidence of overall wound complications (RR = 0.93, P = 0.48), seroma (RR = 1.10, P = 0.79), hematoma (RR = 0.63, P = 0.36) and hospital readmission (RR = 1.41, P = 0.15). NPWT significantly increased the occurrence of skin blistering with a RR of 4.60 (P = 0.04). Use of prophylactic NPWT after cesarean delivery among obese women is associated with a significant reduction of surgical site infection.
C1 [Guo, Chenchen] Southeast Univ, Sch Med, Nanjing, Peoples R China.
   [Cheng, Tao; Li, Junsheng] Southeast Univ, Affiliated Zhongda Hosp, Dept Gen Surg, Nanjing 210009, Peoples R China.
C3 Southeast University - China; Southeast University - China
RP Li, JS (通讯作者)，Southeast Univ, Affiliated Zhongda Hosp, Dept Gen Surg, Nanjing 210009, Peoples R China.
EM lijunshenghd@126.com
RI Li, Junsheng/E-4990-2013
OI Guo, Chenchen/0000-0003-3182-8671
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 32
TC 9
Z9 11
U1 1
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0020-7292
EI 1879-3479
J9 INT J GYNECOL OBSTET
JI Int. J. Gynecol. Obstet.
PD SEP
PY 2022
VL 158
IS 3
BP 502
EP 511
DI 10.1002/ijgo.14058
EA DEC 2021
PG 10
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 3R2NM
UT WOS:000731212700001
PM 34860421
DA 2026-07-24
ER

PT J
AU McKanna, M
   Geraci, J
   Hall, K
   Hauan, B
   Howell, M
   Huey, T
   Lucius, A
   Mendez-Eastman, S
   Purcell, K
   Raizman, R
   Shepherd, D
   Gabriel, A
AF McKanna, Melissa
   Geraci, Jamie
   Hall, Kimberly
   Hauan, Brigitta
   Howell, Melania
   Huey, Trudy
   Lucius, Adora
   Mendez-Eastman, Susan
   Purcell, Kedrin
   Raizman, Rose
   Shepherd, Dawn
   Gabriel, Allen
TI Clinician Panel Recommendations for Use of Negative Pressure Wound
   Therapy with Instillation
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE negative pressure wound therapy; therapeutic irrigation; nursing care;
   clinical skills
AB Addition, of an instilled topical wound solution to negative pressure wound therapy (NPWT) is, designed to facilitate regular Wound cleansing to help improve outcomes of some complex wounds, but the addition of instillation to NPWT adds a level of complexity to the wound care process. The paucity of knowledge and experience with instillation may affect optimal use of this treatment modality. In an effort to address this knowledge gap, a 2-day panel meeting of nurses (N = 11) with experience using negative pressure wound therapy with instillation and dwell time (NPWTi-d) was convened to discuss their usage recommendations for managing wounds with this treatment modality in the acute care setting. Panelists reviewed available evidence and presented recommendations for managing wounds treated with NPWTi-d. Panelists agreed NPWTi-d is primarily suited to prepare surgical or nonsurgical wounds for delayed, primary closure and preparing/protecting periwound skin improves maintenance of a tight seal. Educating a team of nurses on basic NPWTi-d troubleshooting, providing a short checklist of tasks to perform every shift, and organizing needed supplies and resources may help continuity of care and prevent problems. Panelists also emphasized the importance of wound assessment and documentation and recommend educating the patient, family members; and other members of the patient-care team. Research to compare the safety, efficacy, and effectiveness of NPWTi-d and other irrigation techniques on patient outcomes and research to validate these recommendations is needed.
C1 [McKanna, Melissa] Union Hosp, 1606 N 7th St, Terre Haute, IN 47804 USA.
   [Geraci, Jamie] Bethesda North Hosp, Amelia, OH USA.
   [Hall, Kimberly] Carilion Clin, Roanoke, VA USA.
   [Hauan, Brigitta] UW Northwest Hosp, Seattle, WA USA.
   [Howell, Melania] Emanuel Med Ctr, Turlock, CA USA.
   [Huey, Trudy] Catawba Valley Med Ctr, Hickory, NC USA.
   [Lucius, Adora] UT Southwestern Med Ctr, Dallas, TX USA.
   [Mendez-Eastman, Susan] Nebraska Med, Bellevue, NE USA.
   [Purcell, Kedrin] Select Specialty Hosp, Newberry, FL USA.
   [Raizman, Rose] Shoshray Consulting, ET, Toronto, ON, Canada.
   [Shepherd, Dawn] Parkland Hlth & Hosp Syst, Dallas, TX USA.
   [Gabriel, Allen] PeaceHlth Med Grp, Dept Plast Surg, Vancouver, WA USA.
C3 University of Texas System; University of Texas Southwestern Medical
   Center
RP McKanna, M (通讯作者)，Union Hosp, 1606 N 7th St, Terre Haute, IN 47804 USA.
EM mmckanna@uhhg.org
RI Gabriel, Allen/AFK-3548-2022
CR Brinkert D, 2013, INT WOUND J, V10, P56, DOI 10.1111/iwj.12176
   Fluieraru S, 2013, J WOUND CARE, V22, P293, DOI 10.12968/jowc.2013.22.6.293
   Gabriel Allen, 2014, Eplasty, V14, pe41
   Gabriel Allen, 2014, Plast Surg Nurs, V34, P88, DOI 10.1097/PSN.0000000000000033
   Gabriel A, 2012, INT WOUND J, V9, P25, DOI 10.1111/j.1742-481X.2012.01014.x
   Gabriel A, 2008, INT WOUND J, V5, P399, DOI 10.1111/j.1742-481X.2007.00423.x
   Goss SG, 2014, J AM COLL CLIN WOUND, V4, P74, DOI DOI 10.1016/J.JCCW.2014.02.001
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Kim PJ, 2015, PLAST RECONSTR SURG, V136, p657E, DOI 10.1097/PRS.0000000000001709
   Kim Paul J, 2015, Surg Technol Int, V26, P51
   Kim PJ, 2014, PLAST RECONSTR SURG, V133, P709, DOI 10.1097/01.prs.0000438060.46290.7a
   Kim Pyoungsik., 2015, PODIATR TODAY S, P1
   Lessing C, 2011, WOUNDS, V23, P309
   Raad W, 2010, INT WOUND J, V7, P81, DOI 10.1111/j.1742-481X.2010.00658.x
   Schintler MV, 2010, J PLAST RECONSTR AES, V63, pE564, DOI 10.1016/j.bjps.2009.12.013
   Wolvos T, 2013, WOUNDS, V25, P75
NR 16
TC 16
Z9 18
U1 0
U2 5
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD APR
PY 2016
SU S
BP 3
EP 14
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DK2AP
UT WOS:000374717300001
DA 2026-07-24
ER

PT J
AU Kurazumi, H
   Suzuki, R
   Nawata, R
   Yokoyama, T
   Tsubone, S
   Matsuno, Y
   Mikamo, A
   Hamano, K
AF Kurazumi, Hiroshi
   Suzuki, Ryo
   Nawata, Ryosuke
   Yokoyama, Toshiki
   Tsubone, Sarii
   Matsuno, Yutaro
   Mikamo, Akihito
   Hamano, Kimikazu
TI Feasibility of open chest management with modified negative pressure
   wound therapy immediately after cardiac surgery
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Delayed sternal closure; Open chest management; Negative wound pressure
   therapy
ID DELAYED STERNAL CLOSURE
AB Prolonged surgery, cardiopulmonary bypass or cardiac arrest can lead to myocardial, mediastinal and pulmonary oedema.
   OBJECTIVES To evaluate the feasibility of open chest management with our modified negative pressure wound therapy immediately after cardiac surgery as a therapy for atypical tamponade. METHODS Open chest with modified negative pressure wound therapy was performed immediately after cardiac surgery. The surface of the heart and the vessels were covered with non-adherent siliconized gauze. The sternal halves were stented using edge-cut disposable syringes to maintain a larger mediastinal cavity. Approximately 45 mm of distance was kept between the sternal edges. A trimmed sterile polyvinyl foam sponge was inserted into the mediastinum, the entire wound was sealed and negative pressure (-50 to -75 mmHg) was applied using a suction generator. Delayed chest closure was performed in a standard manner once the haemodynamic status was stabilizsed. RESULTS The mortality rate was 3/15 (20%) patients. Deep sternal wound infection occurred in 1/15 (6.7%) patients. Five patients were extubated during the open chest management. Sternal closure was delayed for median of 3 days after the initial surgery. There was no incidence of bleeding complications or need for additional haemostatic procedures. CONCLUSIONS Negative pressure wound therapy performed immediately after cardiac surgery was feasible in our small number of patients. Clinical registration number Study ID: 2020-149.
C1 [Kurazumi, Hiroshi; Suzuki, Ryo; Nawata, Ryosuke; Yokoyama, Toshiki; Tsubone, Sarii; Matsuno, Yutaro; Mikamo, Akihito; Hamano, Kimikazu] Yamaguchi Univ, Dept Surg & Clin Sci, Div Cardiac Surg, Grad Sch Med, Ube, Yamaguchi 7558505, Japan.
C3 Yamaguchi University
RP Suzuki, R (通讯作者)，Yamaguchi Univ, Dept Surg & Clin Sci, Div Cardiac Surg, Grad Sch Med, Ube, Yamaguchi 7558505, Japan.
EM ryo-s@yamaguchi-u.ac.jp
OI Kurazumi, Hiroshi/0000-0002-4009-7391
FU Grants-in-Aid for Scientific Research [22K08960] Funding Source: KAKEN
CR HAKIMI M, 1994, J THORAC CARDIOV SUR, V107, P925
   Howk K, 2016, ANN VASC SURG, V31, P186, DOI 10.1016/j.avsg.2015.09.007
   Kay P H, 1989, Eur J Cardiothorac Surg, V3, P255, DOI 10.1016/1010-7940(89)90075-4
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   Petzina R, 2010, EUR J CARDIO-THORAC, V38, P110, DOI 10.1016/j.ejcts.2010.01.028
NR 5
TC 5
Z9 5
U1 0
U2 2
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
EI 1569-9285
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD JUN 15
PY 2022
VL 35
IS 1
DI 10.1093/icvts/ivac041
EA MAR 2022
PG 4
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 2Q4PZ
UT WOS:000767455500001
PM 35257176
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Jorgensen, MG
   Toyserkani, NM
   Hyldig, N
   Chakera, AH
   Hölmich, LR
   Thomsen, JB
   Sorensen, JA
AF Jorgensen, Mads Gustaf
   Toyserkani, Navid Mohammadpour
   Hyldig, Nana
   Chakera, Annette Hougaard
   Holmich, Lisbet Rosenkrantz
   Thomsen, Jorn Bo
   Sorensen, Jens Ahm
TI Prevention of seroma following inguinal lymph node dissection with
   prophylactic, incisional, negative-pressure wound therapy (SEROMA
   trial): study protocol for a randomized controlled trial
SO TRIALS
LA English
DT Article
DE Prevention; Negative-pressure wound therapy; Seroma; Surgical-site
   infection; Lymphedema; Lymph node dissection; Melanoma
AB Background: Radical inguinal lymphadenectomy (ILND) for metastatic melanoma is associated with a high complication rate. Seroma is often the first postoperative complication, followed by prolonged wound healing sometimes requiring reoperation, infection, multiple outpatient visits and re-hospitalization. Prevention of seroma may, therefore, lead to a reduction in many of the other complications.
   Methods/design: The primary aim of this randomized study is to investigate whether fewer patients require treatment for seroma by immediate prophylactic application of incisional, Negative-pressure Wound Therapy (iNPWT) following ILND, compared to standard postoperative treatment The secondary outcomes include surgical-site infection, dehiscence, hematoma, length of hospitalization, quality of life, safety, long-term assessment of lymphedema and non-inferiority oncological outcome. Data will be registered prospectively at check-ups after 7 and 14 days, 1 and 3 months and 2 years after inguinal lymphadenectomy using case report forms and questionnaires and stored in a secure online database.
   Discussion: To our knowledge, this trial is the first randomized study evaluating negative-pressure wound therapy as a prophylactic intervention for complications following melanoma-related ILND. The results from this trial will hopefully determine the efficacy and safety of prophylactic iNPWT treatment in prevention of the clinical relevant short- and long-term postoperative complications following ILND and may provide an evidence base for the an improved postoperative regimen.
C1 [Jorgensen, Mads Gustaf; Toyserkani, Navid Mohammadpour; Thomsen, Jorn Bo; Sorensen, Jens Ahm] Odense Univ Hosp, Dept Plast Surg, Sdr Blvd 29, DK-5000 Odense, Denmark.
   [Hyldig, Nana] Odense Univ Hosp, Hans Christian Andersens Children Hosp, Odense, Denmark.
   [Chakera, Annette Hougaard; Holmich, Lisbet Rosenkrantz] Herlev Gentofte Hosp, Dept Plast Surg, Herlev, Denmark.
   [Toyserkani, Navid Mohammadpour] Roskilde Hosp, Dept Plast Surg, Roskilde, Denmark.
C3 University of Southern Denmark; Odense University Hospital; University
   of Southern Denmark; Odense University Hospital
RP Sorensen, JA (通讯作者)，Odense Univ Hosp, Dept Plast Surg, Sdr Blvd 29, DK-5000 Odense, Denmark.
EM jens.sorensen@rsyd.dk
RI ; Sørensen, Jens Ahm/D-6279-2014; Hölmich, Lisbet/P-1614-2018; Hyldig,
   Nana/AAH-5220-2020
OI Chakera, Annette Hougaard/0000-0002-3859-0814; Sørensen, Jens
   Ahm/0000-0003-4903-0094; Jørgensen, Mads Gustaf/0000-0002-8755-3446;
   Hyldig, Nana/0000-0001-6758-6294
FU company SmithNephew
FX The iNPWT devices used in this study have been granted to JAS by the
   company Smith&Nephew. The grant is of unrestricted nature and the grant
   provider has no influence on the study design, data collection, data
   analysis, interpretation of results or writing of the report.
CR Agrawal A, 2006, ANZ J SURG, V76, P1088, DOI 10.1111/j.1445-2197.2006.03949.x
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NR 26
TC 11
Z9 15
U1 0
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1745-6215
J9 TRIALS
JI Trials
PD AUG 15
PY 2018
VL 19
AR 441
DI 10.1186/s13063-018-2757-6
PG 8
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA GQ6OX
UT WOS:000441839900001
PM 30111378
OA Green Submitted, Green Published, Green Accepted, gold
DA 2026-07-24
ER

PT J
AU Isik, A
   Memis, U
AF Isik, Arda
   Memis, Ufuk
TI Invited Commentary: The Efficacy of VAMMFT Compared to "Bogota Bag" in
   Achieving Sheath Closure Following Temporary Abdominal Closure at Index
   Laparotomy for Trauma
SO WORLD JOURNAL OF SURGERY
LA English
DT Editorial Material
ID VACUUM-ASSISTED CLOSURE; OPEN ABDOMEN
C1 [Isik, Arda] Istanbul Medeniyet Univ, Sch Med, Gen Surg Dept, Istanbul, Turkiye.
   [Memis, Ufuk] Erzincan Binali Yildirim Univ, Sch Med, Gen Surg Dept, Erzincan, Turkiye.
C3 Istanbul Medeniyet University; Erzincan Binali Yildirim University
RP Isik, A (通讯作者)，Istanbul Medeniyet Univ, Sch Med, Gen Surg Dept, Istanbul, Turkiye.
EM kararda@yahoo.com
RI ISIK, ARDA/H-4772-2019
OI ISIK, ARDA/0000-0001-9493-4055
CR Acosta S, 2016, EUR J VASC ENDOVASC, V51, P371, DOI 10.1016/j.ejvs.2015.10.014
   Hougaard HT, 2014, INT WOUND J, V11, P13, DOI 10.1111/iwj.12281
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   Seternes A, 2010, EUR J VASC ENDOVASC, V40, P60, DOI 10.1016/j.ejvs.2010.02.018
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NR 11
TC 3
Z9 3
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD JUN
PY 2023
VL 47
IS 6
BP 1442
EP 1443
DI 10.1007/s00268-023-06931-8
EA FEB 2023
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AK6A0
UT WOS:000927340000002
PM 36745199
DA 2026-07-24
ER

PT J
AU Cremonini, C
   Strambi, S
   Musetti, S
   Cobuccio, L
   Tartaglia, D
   Coccolini, F
   Chiarugi, M
AF Cremonini, C.
   Strambi, S.
   Musetti, S.
   Cobuccio, L.
   Tartaglia, D.
   Coccolini, F.
   Chiarugi, M.
TI Closed negative pressure wound therapy vs standard primary closure in
   emergency laparotomies: A prospective case-control study
SO JOURNAL OF TISSUE VIABILITY
LA English
DT Editorial Material
ID SURGICAL SITE INFECTION; RISK-FACTORS; INCISION MANAGEMENT;
   ABDOMINAL-SURGERY; OUTCOMES; IMPACT; TRIAL
C1 [Cremonini, C.; Strambi, S.; Musetti, S.; Cobuccio, L.; Tartaglia, D.; Coccolini, F.; Chiarugi, M.] Univ Pisa, Gen & Emergency Surg Unit, Pisa, Italy.
C3 University of Pisa
RP Cremonini, C (通讯作者)，Pisa Univ Hosp, Gen Emergency & Trauma Surg, Via Paradisa 2, I-56124 Pisa, Italy.
EM c.cremonini89@gmail.com
RI Cobuccio, Ludovico Gennaro/HKF-3630-2023; Strambi, Silvia/AAS-4799-2020;
   Tartaglia, Dario/AAJ-1735-2020
OI Strambi, Silvia/0000-0002-2757-2725; Cremonini,
   Camilla/0000-0003-1503-7087
CR Alkaaki A, 2019, CAN J SURG, V62, P111, DOI 10.1503/cjs.004818
   Badia JM, 2017, J HOSP INFECT, V96, P1, DOI 10.1016/j.jhin.2017.03.004
   Ban KA, 2017, J AM COLL SURGEONS, V224, P59, DOI 10.1016/j.jamcollsurg.2016.10.029
   Bohnen JD, 2016, J TRAUMA ACUTE CARE, V81, P122, DOI 10.1097/TA.0000000000001015
   Boland PA, 2021, IRISH J MED SCI, V190, P261, DOI 10.1007/s11845-020-02283-7
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   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
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NR 30
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0965-206X
EI 1876-4746
J9 J TISSUE VIABILITY
JI J. Viab.
PD MAY
PY 2025
VL 34
IS 2
AR 100864
DI 10.1016/j.jtv.2025.100864
EA FEB 2025
PG 6
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA X6J6F
UT WOS:001426390200001
PM 39923732
OA hybrid
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI Effect of negative pressure wound therapy on the expression of TNF- α,
   IL-β, MMP-2, MMP-3, and TIMP-1 in wound fluid of adults with pressure
   ulcers
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 1067-1927
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR-APR
PY 2005
VL 13
IS 2
BP A16
EP A16
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 913EA
UT WOS:000228133200068
DA 2026-07-24
ER

PT J
AU Doody, R
   Cronin, B
   O'Brien, EO
AF Doody, Robert
   Cronin, Brett
   O'Brien, E. Orestes
TI Right Ventricular Rupture After Extubation of a Patient With an Open
   Chest
SO JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
LA English
DT Article
DE extubation; open chest; ventricular rupture; mediastinitis; right
   ventricle
ID VACUUM-ASSISTED CLOSURE; CARDIAC-SURGERY; MEDIASTINITIS; COMPLICATION;
   DEVICE
C1 [Doody, Robert; O'Brien, E. Orestes] Univ Calif San Diego, Anesthesiol Crit Care, San Diego, CA USA.
   [Cronin, Brett] Univ Calif San Diego, Anesthesiol Cardiothorac Anesthesia, San Diego, CA USA.
C3 University of California System; University of California San Diego;
   University of California System; University of California San Diego
RP Doody, R (通讯作者)，Univ Calif San Diego, Dept Anesthesiol, 200 W Arbor Dr 8770, San Diego, CA 92103 USA.
EM rmdoody@gmail.com
OI Doody, Robert/0000-0001-7651-9456
CR Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
   Baillot R, 2010, EUR J CARDIO-THORAC, V37, P880, DOI 10.1016/j.ejcts.2009.09.023
   Bapat V, 2008, J CARDIAC SURG, V23, P227, DOI 10.1111/j.1540-8191.2008.00595.x
   CARTIER R, 1993, J THORAC CARDIOV SUR, V106, P1036, DOI 10.1016/S0022-5223(19)33974-1
   Edwin F, 2010, INTERACT CARDIOV TH, V10, P472, DOI 10.1510/icvts.2009.223891C
   Francel TJ, 2001, ANN THORAC SURG, V72, P1411, DOI 10.1016/S0003-4975(00)02008-7
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   Hersh RE, 2001, HEART SURG FORUM, V4, P211
   Hillis LD, 2011, CIRCULATION, V124, P2610, DOI 10.1161/CIR.0b013e31823b5fee
   McCool FD, 2006, CHEST, V129, p48S, DOI 10.1378/chest.129.1_suppl.48S
   Sjögren J, 2011, INTERACT CARDIOV TH, V12, P117, DOI 10.1510/icvts.2010.252668
   Suen HC, 1998, ANN THORAC SURG, V66, P2115, DOI 10.1016/S0003-4975(98)01083-2
NR 12
TC 2
Z9 2
U1 0
U2 0
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1053-0770
EI 1532-8422
J9 J CARDIOTHOR VASC AN
JI J. Cardiothorac. Vasc. Anesth.
PD FEB
PY 2018
VL 32
IS 1
BP 461
EP 463
DI 10.1053/j.jvca.2017.06.037
PG 3
WC Anesthesiology; Cardiac & Cardiovascular Systems; Respiratory System;
   Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Anesthesiology; Cardiovascular System & Cardiology; Respiratory System
GA FV6ZG
UT WOS:000424730300071
PM 29217247
DA 2026-07-24
ER

PT J
AU Muthu, S
   Viswanathan, VK
   Ponnusamy, DVK
AF Muthu, Sathish
   Viswanathan, Vibhu Krishnan
   Ponnusamy, Dhibin Vikash Kolarpatti
TI Response to the Letter to the Editor on "Role of Prophylactic Negative
   Pressure Wound Therapy in Reducing Surgical-Site Infections in Spine
   Surgery - A Systematic Review and Meta-Analysis"
SO GLOBAL SPINE JOURNAL
LA English
DT Letter; Early Access
C1 [Muthu, Sathish; Viswanathan, Vibhu Krishnan; Ponnusamy, Dhibin Vikash Kolarpatti] Orthopaed Res Grp, Dept Spine Surg, Coimbatore 641045, Tamil Nadu, India.
   [Muthu, Sathish] Vinayaka Missions Res Fdn, Aarupadai Veedu Med Coll & Hosp, Cent Res Lab, Pondicherry, India.
   [Viswanathan, Vibhu Krishnan] Univ Alabama Birmingham, Dept Orthopaed Surg, Birmingham, AL USA.
   [Ponnusamy, Dhibin Vikash Kolarpatti] Govt Med Coll, Dept Orthopaed, Karur, India.
C3 Vinayaka Mission's Research Foundation; Aarupadai Veedu Medical College
   & Hospital; University of Alabama System; University of Alabama
   Birmingham
RP Muthu, S (通讯作者)，Orthopaed Res Grp, Dept Spine Surg, Coimbatore 641045, Tamil Nadu, India.
EM drsathishmuthu@gmail.com
RI Viswanathan, Vibhu/Q-1461-2017; Muthu, Sathish/G-5756-2018
OI K P, DHIBIN VIKASH/0000-0003-1071-0084
CR Aung Nyan Min, 2026, Cochrane Evid Synth Methods, V4, pe70067, DOI 10.1002/cesm.70067
   Imtiaz H, 2024, CUREUS J MED SCIENCE, V16, DOI 10.7759/cureus.69214
   Muthu S, 2026, GLOB SPINE J, DOI 10.1177/21925682261426264
   Sathish M, 2021, GLOB SPINE J, V11, P378, DOI 10.1177/2192568220906810
NR 4
TC 0
Z9 0
U1 0
U2 0
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 2192-5682
EI 2192-5690
J9 GLOB SPINE J
JI Glob. Spine J.
PD 2026 MAR 16
PY 2026
DI 10.1177/21925682261436404
EA MAR 2026
PG 2
WC Clinical Neurology; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Orthopedics
GA FD9LF
UT WOS:001716451500001
PM 41839832
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Lin, XY
   Zan, T
   Wu, XL
   Li, GS
   Tan, WQ
AF Lin, Xiao-Ying
   Zan, Tao
   Wu, Xiao-Li
   Li, Guang-Shuai
   Tan, Wei-Qiang
TI Editorial: Recent innovations to inhibit scar formation for better skin
   regeneration (vol 11, 1351577, 2024)
SO FRONTIERS IN SURGERY
LA English
DT Correction
DE wound healing; scar formation; scar treatment; mechanical force;
   negative pressure wound therapy; skin flap
C1 [Lin, Xiao-Ying; Tan, Wei-Qiang] Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Dept Plast Surg, Hangzhou, Peoples R China.
   [Zan, Tao; Wu, Xiao-Li] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Dept Plast & Reconstruct Surg, Shanghai, Peoples R China.
   [Li, Guang-Shuai] Zhengzhou Univ, Affiliated Hosp 1, Dept Plast & Reconstruct Surg, Zhengzhou, Peoples R China.
C3 Zhejiang University; Shanghai Jiao Tong University; Zhengzhou University
RP Tan, WQ (通讯作者)，Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Dept Plast Surg, Hangzhou, Peoples R China.
EM tanweixxxx@zju.edu.cn
RI lin, xiaoying/ACG-0057-2022; Tan, Wei-Qiang/JCE-4732-2023
OI 黎, 奇刚/0009-0003-5227-6420
CR Tan WQ, 2023, FRONT SURG, V10, DOI 10.3389/fsurg.2023.1325832
NR 1
TC 0
Z9 0
U1 1
U2 3
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-875X
J9 FRONT SURG
JI Front. Surg.
PD JAN 10
PY 2024
VL 11
AR 1351577
DI 10.3389/fsurg.2024.1351577
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA IZ6D8
UT WOS:001170196500001
PM 38274982
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Pu, LLQ
AF Pu, Lee L. Q.
TI An alternative approach for soft-tissue coverage of a complex wound in
   the foot and ankle with vacuum-assisted closure over artificial dermis
   and subsequent skin graft
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Letter
ID DEFECTS
C1 Univ Calif Davis, Div Plast Surg, Sacramento, CA 95817 USA.
C3 University of California System; University of California Davis
RP Pu, LLQ (通讯作者)，Univ Calif Davis, Div Plast Surg, 2221 Stockton Blvd,Suite 2123, Sacramento, CA 95817 USA.
EM lee.pu@ucdmc.ucdavis.edu
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Komorowska-Timek E, 2005, PLAST RECONSTR SURG, V115, P1010, DOI 10.1097/01.PRS.0000154210.60284.C6
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Tufaro AP, 2007, PLAST RECONSTR SURG, V120, P638, DOI 10.1097/01.prs.0000270298.68331.8a
NR 5
TC 11
Z9 12
U1 0
U2 0
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD DEC
PY 2009
VL 62
IS 12
BP E682
EP E684
DI 10.1016/j.bjps.2008.08.032
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 529NK
UT WOS:000272524100080
PM 19027380
DA 2026-07-24
ER

PT J
AU Yi, BS
   Xu, LC
AF Yi, Bingshu
   Xu, Lianchun
TI Comment on "Comparison of Scar Quality Between Primary Incisional
   Negative Pressure Wound Therapy and Conventional Surgical Dressing in
   Patients with Closed Forearm Fractures Treated Surgically: A Randomised
   Controlled Trial"
SO AESTHETIC PLASTIC SURGERY
LA English
DT Letter; Early Access
C1 [Xu, Lianchun] Dalian Univ Technol, Dalian Municipal Cent Hosp, Dept Hand & Foot Microsurg, Cent Hosp, Dalian 116021, Peoples R China.
   [Yi, Bingshu] Dalian Aidelige Med Aesthet Clin Co Ltd, Dept Plast Surg, Dalian 116021, Peoples R China.
C3 Dalian University of Technology
RP Xu, LC (通讯作者)，Dalian Univ Technol, Dalian Municipal Cent Hosp, Dept Hand & Foot Microsurg, Cent Hosp, Dalian 116021, Peoples R China.
EM 15940820737@163.com; xulianchun120@163.com
CR Cooper HJ, 2023, PRS-GLOB OPEN, V11, DOI 10.1097/GOX.0000000000004722
   Groenen H, 2023, ECLINICALMEDICINE, V62, DOI 10.1016/j.eclinm.2023.102105
   Liu H, 2024, J ORTHOP SURG RES, V19, DOI 10.1186/s13018-024-05038-7
   Sharran M, 2026, AESTHET PLAST SURG, V50, P1411, DOI 10.1007/s00266-025-05014-4
   Timmermans FW, 2022, WOUND REPAIR REGEN, V30, P210, DOI 10.1111/wrr.13001
NR 5
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0364-216X
EI 1432-5241
J9 AESTHET PLAST SURG
JI Aesthet. Plast. Surg.
PD 2026 JUN 15
PY 2026
DI 10.1007/s00266-026-06080-y
EA JUN 2026
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA JO3RB
UT WOS:001794106800001
PM 42298153
DA 2026-07-24
ER

PT J
AU Li, Z
   Wu, JW
   Zhang, HW
   Topaz, M
   He, F
AF Li, Zhen
   Wu, Jiang-Wen
   Zhang, Hong-Wei
   Topaz, Moris
   He, Fang
TI 撤稿声明: Regulated negative pressure wound therapy combined TopClosure® in
   treatment of skin defect for open fracture in lower extremity: a case
   report (Retraction of Vol 10, Pg 12659, 2017)
SO INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
LA English
DT Retraction
CR Li Z, 2017, INT J CLIN EXP MED, V10, P12659
NR 1
TC 0
Z9 0
U1 0
U2 5
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1940-5901
J9 INT J CLIN EXP MED
JI Int. J. Clin. Exp. Med.
PY 2018
VL 11
IS 6
BP 6383
EP 6383
PG 1
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA GL8HL
UT WOS:000437459200125
DA 2026-07-24
ER

PT J
AU Chen, JH
   Li, YB
   Li, DG
   Zeng, XM
   Yao, QY
   Fu, J
   Wang, GH
   Huang, XY
AF Chen, Ju-hua
   Li, Yu-bo
   Li, De-gang
   Zeng, Xiao-mei
   Yao, Qiu-yuan
   Fu, Jun
   Wang, Gong-he
   Huang, Xiao-yan
TI Vacuum sealing drainage to treat Fournier's gangrene
SO BMC SURGERY
LA English
DT Article
DE Fournier's gangrene; Vacuum sealing drainage; Debridement; Wound
   reconstruction; Soft tissue infection; Necrosis
ID ASSISTED CLOSURE; RETROSPECTIVE ANALYSIS; THERAPY
AB BackgroundVacuum sealing drainage (VSD) is widely applied in complex wound repair. We aimed to compare traditional debridement and drainage and VSD in treating Fournier's gangrene (FG).MethodsData of patients surgically treated for FG were retrospectively analyzed.ResultsOf the 36 patients (men: 31, women: 5; mean age: 53.5 & PLUSMN; 11.3 [range: 28-74] years) included in the study, no patients died. Between-group differences regarding sex, age, BMI, time from first debridement to wound healing, number of debridements, FGSI, and shock were not statistically significant (P > 0.05). However, lesion diameter, colostomy, VAS score, dressing changes, analgesic use, length of hospital stay, and wound reconstruction method (& chi;(2) = 5.43, P = 0.04) exhibited statistically significant differences. Tension-relieving sutures (6 vs. 21) and flap transfer (4 vs. 2) were applied in Groups I and II, respectively.ConclusionVSD can reduce postoperative dressing changes and analgesic use, and shrunk the wound area, thereby reducing flap transfer in wound reconstruction.
C1 [Chen, Ju-hua] Jinggangshan Univ, Colorectal Surg Div, Affiliated Hosp, Jian 343000, Jiangxi, Peoples R China.
   [Li, Yu-bo; Li, De-gang; Yao, Qiu-yuan; Fu, Jun; Wang, Gong-he; Huang, Xiao-yan] Guangxi Univ Chinese Med, Colorectal Surg Div, Affiliated Hosp 1, Dongge Rd 89-9, Nanning 530023, Guangxi, Peoples R China.
   [Zeng, Xiao-mei] Colorectal Surg Div, Tradit Chinese Med Guiping city, Guiping 537200, Guangxi, Peoples R China.
C3 Jinggangshan University; Guangxi University of Chinese Medicine
RP Li, YB (通讯作者)，Guangxi Univ Chinese Med, Colorectal Surg Div, Affiliated Hosp 1, Dongge Rd 89-9, Nanning 530023, Guangxi, Peoples R China.
EM liyubo0323004@126.com
OI Li, Yubo/0009-0006-1016-1408
CR Boughanmi F, 2021, PAN AFR MED J, V38, DOI 10.11604/pamj.2021.38.23.25863
   Cuccia G, 2009, UROL INT, V82, P426, DOI 10.1159/000218532
   Czymek R, 2009, AM J SURG, V197, P168, DOI 10.1016/j.amjsurg.2008.07.053
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   Gul MO, 2021, NIGER J CLIN PRACT, V24, P1277, DOI 10.4103/njcp.njcp_387_20
   Huang QQ, 2021, TRANSL PEDIATR, V10, P2489, DOI 10.21037/tp-21-399
   Hung MC, 2016, UROL SCI, V27, P148, DOI 10.1016/j.urols.2015.06.294
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NR 19
TC 11
Z9 13
U1 1
U2 17
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2482
J9 BMC SURG
JI BMC Surg.
PD JUL 26
PY 2023
VL 23
IS 1
AR 211
DI 10.1186/s12893-023-02109-0
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA N0FZ7
UT WOS:001033891800003
PM 37496026
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Nie, PF
   Zhang, CH
AF Nie, Pengfei
   Zhang, Canhong
TI Effect of Vacuum Sealing Drainage on Soft Tissue Injury of Traumatic
   Fracture and Its Effect on Wound Recovery
SO EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
LA English
DT Article
ID HIP DISLOCATION; THERAPY; EPIDEMIOLOGY; STRAINS
AB Purpose. The current work is mainly to explore the effect of vacuum sealing drainage (VSD) on soft tissue injury (STI) caused by traumatic fractures (TFs) and its effect on wound recovery. Methods. We first selected 90 patients with TF STI from May 2019 to May 2021, of which 40 patients (control group) received routine treatment, and the other 50 patients (observation group) were treated with VSD. The curative effect, rehabilitation (changing dressing frequency, healing time, and hospitalization time), pain severity, patient comfort, and complications were evaluated and compared. Results. The observation group exhibited a higher total effective rate, lower dressing change frequency, complication rate, and shorter healing time and hospital stay than the control group, which are statistically significant. Statistically milder pain sensation and better patient comfort were also determined in the observation group. Conclusions. VSD is effective and safe in the treatment of TF-induced sexually transmitted infections, which can effectively accelerate wound recovery while reducing pain sensation and improving patient comfort, with clinical promotion value.
C1 [Nie, Pengfei] Beilun Dist Peoples Hosp, Dept Orthoped, Ningbo 315800, Zhejiang, Peoples R China.
   [Zhang, Canhong] Fujian Med Univ, Quanzhou Hosp 1, Dept Orthopaed, Quanzhou 362000, Fujian, Peoples R China.
C3 Fujian Medical University
RP Nie, PF (通讯作者)，Beilun Dist Peoples Hosp, Dept Orthoped, Ningbo 315800, Zhejiang, Peoples R China.
EM niepengfei188@163.com; zhangch1988@126.com
FU Ningbo Beilun People's Hospital Fund;  [2022YJJJYB04]
FX The subject in Beilun District people's Hospital and A preliminary study
   on mechanical analysis of fracture around clavicular hook Ningbo Beilun
   People's Hospital Fund (2022YJJJYB04).
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NR 33
TC 5
Z9 7
U1 1
U2 7
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1741-427X
EI 1741-4288
J9 EVID-BASED COMPL ALT
JI Evid.-based Complement Altern. Med.
PD SEP 29
PY 2022
VL 2022
AR 7107090
DI 10.1155/2022/7107090
PG 6
WC Integrative & Complementary Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Integrative & Complementary Medicine
GA 5I4JM
UT WOS:000868325000002
PM 36212953
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Walls, B
   Mohammad, S
   Campbell, J
   Archer, L
   Beale, J
AF Walls, B.
   Mohammad, S.
   Campbell, J.
   Archer, L.
   Beale, J.
TI Negative pressure dressings for severe hidradenitis suppurativa (acne
   inversa): a case report
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE hidradenitis suppurativa; negative pressure wound therapy
AB Hidradenitis suppurativa (HS) is a frustrating disease to treat for both the patient and the practitioner. In severe cases, aggressive management will often have a more tolerable outcome. We present the case of a 46-year-old gentleman with a long-standing history of severe HS, who was treated successfully with wide surgical excision, followed by a full-thickness skin graft and negative pressure wound therapy (both pre- and post-operatively). A review of the literature revealed few reports of HS treatment using these sequential steps
C1 [Walls, B.; Mohammad, S.; Campbell, J.; Archer, L.; Beale, J.] HCA Largo Med Ctr, Wound Care Ctr, Largo, FL USA.
RP Walls, B (通讯作者)，HCA Largo Med Ctr, Wound Care Ctr, Largo, FL USA.
EM blissy79@comcast.net
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NR 19
TC 5
Z9 8
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
J9 J WOUND CARE
JI J. Wound Care
PD OCT
PY 2010
VL 19
IS 10
BP 457
EP 460
DI 10.12968/jowc.2010.19.10.79094
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA V29CP
UT WOS:000208726800008
PM 20948495
DA 2026-07-24
ER

PT J
AU Luo, HM
   Chi, YF
   Chen, X
   Chai, JK
AF Luo, Hongmin
   Chi, Yunfei
   Chen, Xin
   Chai, Jiake
TI Usage of Negative Pressure Wound Therapy in Pseudoepitheliomatous
   Hyperplasia Secondary to Burn Injury: A Case Series
SO JOURNAL OF BURN CARE & RESEARCH
LA English
DT Article
AB Pseudoepitheliomatous hyperplasia (PEH) is a reactive epithelial proliferation secondary to a wide range of stimuli, including traumatic injury, inflammation, infection, and tumors of the skin. PEH secondary to burn injury is rarely reported. We report three cases of PEH patients after burn injury. All three cases were confirmed with the existence of bacterial infection, and all these cases were second- or third-degree burns. All three patients were treated with negative pressure wound therapy after wound debridement or tangential excision. All the wounds healed without split-thickness skin grafting and recurrence.
C1 [Luo, Hongmin] Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Dept Burns & Wound Repair Surg, Guangzhou, Guangdong, Peoples R China.
   [Chi, Yunfei; Chen, Xin; Chai, Jiake] Peoples Liberat Army Gen Hosp, Burn Inst, Med Ctr 4, 51 Fu Cheng Rd, Beijing 100048, Peoples R China.
C3 Guangdong Academy of Medical Sciences & Guangdong General Hospital;
   Southern Medical University - China; Chinese People's Liberation Army
   General Hospital
RP Chi, YF (通讯作者)，Peoples Liberat Army Gen Hosp, Burn Inst, Med Ctr 4, 51 Fu Cheng Rd, Beijing 100048, Peoples R China.
EM chi_yunfei@126.com
RI Luo, Hongmin/ABG-6510-2021
FU People's Liberation Army General Hospital Big Data Project "The
   establishment of emergency clinical database for burn and study of scar
   prediction model" [2019MBD-054]
FX People's Liberation Army General Hospital Big Data Project "The
   establishment of emergency clinical database for burn and study of scar
   prediction model" (2019MBD-054).
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NR 11
TC 1
Z9 1
U1 1
U2 9
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1559-047X
EI 1559-0488
J9 J BURN CARE RES
JI J. Burn Care Res.
PD MAR 23
PY 2022
VL 43
IS 2
BP 492
EP 495
DI 10.1093/jbcr/irab207
EA NOV 2021
PG 4
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA ZY5BX
UT WOS:000772602800031
PM 34695202
DA 2026-07-24
ER

PT J
AU Ullmann, Y
   Fodor, L
   Ramon, Y
   Soudry, M
   Lerner, L
AF Ullmann, Y
   Fodor, L
   Ramon, Y
   Soudry, M
   Lerner, L
TI The revised "reconstructive ladder" and its applications for high-energy
   injuries to the extremities
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE high-energy injuries; reconstructive ladder; acute shortening; VAC
ID VACUUM-ASSISTED CLOSURE; EXTERNAL FIXATION; THERAPY; MANAGEMENT; SYSTEM;
   BONE; WOUNDS; WAR
AB In this report, we tried to evaluate the merits of the classic "reconstructive ladder" and other reconstructive tools, such as acute shortening followed by distraction osteogenesis and a vacuum-assisted closure device, for the treatment of high-energy injuries. Thirty-sevcn patients suffering from high-velocity injuries to the extremities caused by war weapons and blast terror attacks were treated at our institution. The fractures were initially stabilized by the Association for the Study of Internal Fixation (AO/ASIF) unilateral tubular external fixator, which was changed 2-3 days later to a circular Ilizarov frame for 19 patients. Temporary acute shortening was performed for 5 patients. Skin grafts were performed for 21 patients, local or regional flaps for 14 patients, and free flaps for 6. Vacuum-assisted closure was selected for 8 patients. The wounds were successfully closed in all the patients. Two patients with upper-linib injuries had nonunion. Motor nerve injuries recovered in 7/10 patients. Due to hypergranulating tissue, 2 patients treated with vacuum-assisted closure (VAC) had to stop treatment early. Their wounds were closed with skin graft or local flap. The classic reconstructive ladder, starting from direct closure and ending with a free flap, should be extended for limb traumas and include acute shortening with or without angulation, followed by distraction osteogenesis and the VAC system on the same step as the free flap.
C1 Technion Israel Inst Technol, Rambam Med Ctr, Dept Plast & Reconstruct Surg, IL-31096 Haifa, Israel.
   Technion Israel Inst Technol, Rambam Med Ctr, Dept Orthopaed Surg, IL-31096 Haifa, Israel.
   Technion Israel Inst Technol, Fac Med, IL-31096 Haifa, Israel.
C3 Technion Israel Institute of Technology; Rambam Health Care Campus;
   Technion Israel Institute of Technology; Rambam Health Care Campus;
   Technion Israel Institute of Technology; Rappaport Faculty of Medicine
RP Ullmann, Y (通讯作者)，Technion Israel Inst Technol, Rambam Med Ctr, Dept Plast & Reconstruct Surg, 8 Haaliya St, IL-31096 Haifa, Israel.
EM y_ullmann@rambam.health.gov.il
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NR 43
TC 41
Z9 47
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD APR
PY 2006
VL 56
IS 4
BP 401
EP 405
DI 10.1097/01.sap.0000201552.81612.68
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 026XP
UT WOS:000236376900014
PM 16557072
DA 2026-07-24
ER

PT J
AU Watt, AJ
   Friedrich, JB
   Huang, JI
AF Watt, Andrew J.
   Friedrich, Jeffrey B.
   Huang, Jerry I.
TI Advances in Treating Skin Defects of the Hand Skin Substitutes and
   Negative-Pressure Wound Therapy
SO HAND CLINICS
LA English
DT Article
DE Hand reconstruction; Skin substitute; Dermal substitute; VAC; Integra
ID DERMAL REGENERATION TEMPLATE; CLINICAL-TRIAL; TISSUE DEFECTS; MATRIX;
   ALLOGRAFT; CLOSURE; INTEGRA; GRAFTS; RECONSTRUCTION; MANAGEMENT
AB Surgeons and scientists have been developing alternative methods of hand reconstruction that may play an adjunctive role to, or completely supplant, more traditional reconstructive modalities. This article provides an overview of these emerging techniques, with an emphasis on skin substitutes and negative-pressure wound therapy as they apply to the treatment of soft tissue defects of the hand. The indications, contraindications, and relative advantages and disadvantages of these techniques are discussed in detail.
C1 [Watt, Andrew J.; Huang, Jerry I.] Univ Washington, Hand Ctr, Seattle, WA 98105 USA.
   [Watt, Andrew J.; Huang, Jerry I.] Univ Washington, Dept Orthoped Surg & Sports Med, Seattle, WA 98105 USA.
   [Friedrich, Jeffrey B.] Univ Washington, Dept Surg, Div Plast Surg, Seattle, WA 98105 USA.
   [Friedrich, Jeffrey B.] Univ Washington, Dept Orthopaed, Seattle, WA 98105 USA.
   [Friedrich, Jeffrey B.] Univ Washington, Harborview Med Ctr, Seattle, WA 98104 USA.
C3 University of Washington; University of Washington Seattle; University
   of Washington; University of Washington Seattle; University of
   Washington; University of Washington Seattle; University of Washington;
   University of Washington Seattle; Harborview Medical Center; University
   of Washington; University of Washington Seattle
RP Watt, AJ (通讯作者)，Univ Washington, Hand Ctr, 4245 Roosevelt Ave NE,Box 354740, Seattle, WA 98105 USA.
EM ajwatt50@gmail.com
OI Friedrich, Jeffrey/0000-0002-5245-9708
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NR 35
TC 14
Z9 15
U1 0
U2 9
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0749-0712
EI 1558-1969
J9 HAND CLIN
JI Hand Clin.
PD NOV
PY 2012
VL 28
IS 4
BP 519
EP +
DI 10.1016/j.hcl.2012.08.010
PG 11
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 047XW
UT WOS:000311875800008
PM 23101602
DA 2026-07-24
ER

PT J
AU Hu, FX
   Hu, XX
   Yang, XL
   Han, XH
   Xu, YB
   Li, K
   Yan, L
   Chu, HB
AF Hu, Fu Xing
   Hu, Xiao Xuan
   Yang, Xue Lin
   Han, Xing Hai
   Xu, Yong Bo
   Li, Kun
   Yan, Li
   Chu, Hai Bo
TI Treatment of large avulsion injury in perianal, sacral, and perineal
   regions by island flaps or skin graft combined with vacuum assisted
   closure
SO BMC SURGERY
LA English
DT Article
DE Avulsion; Flap; Trauma; Wound closure techniques
ID PRESSURE WOUND THERAPY; RECTAL GUNSHOT WOUNDS; SEALING DRAINAGE;
   MANAGEMENT; TISSUE; DEVICE; TRAUMA
AB BackgroundTraumatic avulsion injuries to the anus, although uncommon, can result in serious complications and even death. Management of anal avulsion injuries remains controversial and challenging. This study aimed to investigate the clinical effects of treating large skin and subcutaneous tissue avulsion injuries in the perianal, sacral, and perineal regions with island flaps or skin graft combined with vacuum assisted closure.MethodsIsland flaps or skin graft combined with vacuum assisted closure, diverting ileostomy, the rectum packed with double-lumen tubes around Vaseline gauze, negative pressure drainage with continuous distal washing, wounds with skin grafting as well as specialized treatment were performed.ResultsThe injuries healed in all patients. Six cases had incomplete perianal avulsion without wound infection. Wound infection was seen in four cases with annular perianal avulsion and was controlled, and the separated prowl lacuna was closed. The survival rate in 10 patients who underwent skin grafting was higher than 90%. No anal stenosis was observed after surgery, and ileostomy closure was performed at 3months (six cases) and 6months (four cases) after surgery, respectively.ConclusionsCovering a wound with an island flap or skin graft combined with vacuum assisted closure is successful in solving technical problems, protects the function of the anus and rapidly seals the wound at the same time.
C1 [Hu, Fu Xing; Yang, Xue Lin; Han, Xing Hai] 89th Hosp PLA, Dept Burn & Plast Surg, Weifang 261021, Peoples R China.
   [Hu, Xiao Xuan] Ningxia Med Univ, Dept Postgrad, Yinchuan 750004, Peoples R China.
   [Xu, Yong Bo; Li, Kun; Yan, Li; Chu, Hai Bo] 89th Hosp PLA, Dept Gen Surg, Weifang 261021, Peoples R China.
C3 Ningxia Medical University
RP Yan, L; Chu, HB (通讯作者)，89th Hosp PLA, Dept Gen Surg, Weifang 261021, Peoples R China.
EM hfx0323@sina.com; yanli2423@163.com; haibochuwf@163.com
FU Weifang City Scientific Development Project of China [2017YX032]
FX This work was supported by the Weifang City Scientific Development
   Project of China (Grant No. 2017YX032). The funding body had no role in
   the study design, data collection and analysis, or preparation of
   manuscript.
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NR 24
TC 9
Z9 12
U1 0
U2 6
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1471-2482
J9 BMC SURG
JI BMC Surg.
PD JUN 18
PY 2019
VL 19
AR 65
DI 10.1186/s12893-019-0529-1
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA ID9SN
UT WOS:000472027500002
PM 31215452
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Lu, ZY
   Zhang, XX
   Huo, YX
   Zhang, SK
AF Lu, Ziyi
   Zhang, Xinxin
   Huo, Yixuan
   Zhang, Shoukai
TI A case of deep neck abscess treated with a disposable VSD wound care
   device: Case report and review of literature
SO MEDICINE
LA English
DT Article
DE deep neck abscess; treatment; vacuum sealing drainage
AB Rationale: Vacuum sealing drainage is a novel technique for wound treatment that is characterized by adequate drainage and promotes wound healing. We report a case in which negative pressure sealing drainage was applied to treat a deep cervical abscess and achieved a good therapeutic effect. Patient concerns: The abscess in the neck will go down. Diagnoses: Deep neck abscess. Interventions: The usual surgical approach to treating this condition is to make a small incision to incise and drain the patient infected area where it is most visibly swollen or fluctuating, and to place a negative pressure drainage device. Outcomes: Eleven days after the operation, the patient neck recovered well, there was no infection in the operation area, and the patient was discharged from the hospital with improved symptoms. Lessons: This proves that the negative pressure closed drainage technique has potential in the treatment of deep neck abscesses and is also an effective choice in promoting wound healing, which is expected to bring better therapeutic effects to patients treated for deep neck abscesses.
C1 [Lu, Ziyi; Zhang, Xinxin] Gansu Univ Chinese Med, Clin Med Coll 1, Lanzhou, Gansu, Peoples R China.
   [Huo, Yixuan] Ningxia Med Univ, Ningxia, Peoples R China.
   [Zhang, Shoukai] Gansu Prov Hosp, Dept Otolaryngol Head & Neck Surg, Lanzhou, Gansu, Peoples R China.
   [Zhang, Shoukai] Gansu Prov Hosp, Otolaryngol Head Neck Surg, Lanzhou 730000, Peoples R China.
C3 Gansu University of Chinese Medicine; Ningxia Medical University
RP Zhang, SK (通讯作者)，Gansu Prov Hosp, Otolaryngol Head Neck Surg, Lanzhou 730000, Peoples R China.
EM drluziyi@163.com; zhangshoukai1977@126.com; hyxluck0202z@163.com;
   zhangshoukai1977@126.com
OI lu, ziyi/0009-0002-9237-6314
FU Gansu Provincial Natural Fund [22JR5RA664]
FX Gansu Provincial Natural Fund: 22JR5RA664.
CR Chen BL, 2017, MEDICINE, V96, DOI [10.1097/MD.0000000000006511, 10.1097/md.0000000000006511]
   Fiorella ML, 2020, ACTA OTORHINOLARYNGO, V40, P332, DOI 10.14639/0392-100X-N0790
   Gu X, 2021, MEDICINE, V100, DOI 10.1097/MD.0000000000024367
   Hansen BW, 2020, SEMIN ULTRASOUND CT, V41, P74, DOI 10.1053/j.sult.2019.10.001
   Huang T., 2023, Medicine (Baltim), V102, pe32785
   Subspecialty Group of Head and Neck Surgery Editorial Board of Chinese Journal of Otorhinolaryngology Head, 2022, Chin J Otolaryngol Head Neck Surg, V57, P405
NR 6
TC 0
Z9 0
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD MAR 22
PY 2024
VL 103
IS 12
AR e37397
DI 10.1097/MD.0000000000037397
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA MW6J1
UT WOS:001196708800065
PM 38518028
OA Green Published, gold
DA 2026-07-24
ER

PT J
AU Bütter, A
   Emran, M
   Al-Jazaeri, A
   Ouimet, A
AF Butter, Andreana
   Emran, Mohammad
   Al-Jazaeri, Ayman
   Ouimet, Alain
TI Vacuum-assisted closure for wound management in the pediatric population
SO JOURNAL OF PEDIATRIC SURGERY
LA English
DT Article; Proceedings Paper
CT 37th Annual Meeting of the Canadian-Association-of-Paediatric-Surgeons
CY SEP 22-25, 2005
CL Quebec City, CANADA
SP Canadian Assoc Paediat Surg
DE vacuum-assisted closure; wound care; pediatric
ID EXPERIENCE
AB Background/Purpose: Wound management in children has traditionally consisted of daily dressings. Although vacuum-assisted closure (VAC) is well described in the adult literature, there are few reports about children. We reviewed our experience with VAC.
   Methods: A retrospective review from 2003 to 2005 revealed that 16 children underwent VAC. Variables analyzed included demographics, diagnosis, duration and characteristics of VAC, wound closure, recurrence, complications, and cost analysis.
   Results: Sixteen children received VAC therapy at an average age of 12.1 years (range, 1 month -18 years). Indications included tissue loss after pilonidal sinus excision (n = 8, primary = 5, recurrent 3) after wound dehiscence of the abdomen (3), the sternum (2), the back (1), the leg (1), and after chronic postoperative perineal fistula. Average length of VAC use was 23 days, with an average pressure of 104 nun Hg. Wound closure occurred in 15 of 16 patients. Patients with primary pilonidal disease obtained wound closure by 45 days, whereas those with recurrent disease required 72 days. Children with wound dehiscence healed by 28 days. Recurrent sinuses developed in all 3 patients with known recurrent pilonidal disease. Pain in 1 patient required cessation of VAC therapy after 7 days. Follow-up after wound closure averaged 8 months.
   Conclusions: Vacuum-assisted closure is well tolerated in our pediatric population and offers many advantages including fewer dressing changes and an earlier return to daily activities. (c) 2006 Elsevier Inc. All rights reserved.
C1 Hop St Justine, Div Pediat Surg, Montreal, PQ H3T 1C5, Canada.
C3 Universite de Montreal
RP Ouimet, A (通讯作者)，Hop St Justine, Div Pediat Surg, Montreal, PQ H3T 1C5, Canada.
EM amouimet@videotron.ca
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Caniano DA, 2005, J PEDIATR SURG, V40, P128, DOI 10.1016/j.jpedsurg.2004.09.016
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   Mooney JF, 2000, CLIN ORTHOP RELAT R, P26
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Philbeck T E Jr, 1999, Ostomy Wound Manage, V45, P41
   Ramnarine IR, 2002, EUR J CARDIO-THORAC, V22, P1029, DOI 10.1016/S1010-7940(02)00562-6
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
NR 8
TC 59
Z9 65
U1 0
U2 2
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0022-3468
EI 1531-5037
J9 J PEDIATR SURG
JI J. Pediatr. Surg.
PD MAY
PY 2006
VL 41
IS 5
BP 940
EP 942
DI 10.1016/j.jpedsurg.2006.01.061
PG 3
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Pediatrics; Surgery
GA 054PI
UT WOS:000238390700014
PM 16677888
DA 2026-07-24
ER

PT J
AU Thorsteinsson, DT
   Valsson, F
   Geirsson, A
   Gudbjartsson, T
AF Thorsteinsson, David T.
   Valsson, Felix
   Geirsson, Arnar
   Gudbjartsson, Tomas
TI Major cardiac rupture following surgical treatment for deep sternal
   wound infection
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Rupture; Heart; Right ventricle; Deep sternal wound infection; Negative
   pressure wound therapy
AB We report a case of an 80-year old male patient who sustained a major rupture of the right ventricle after surgical revision of an infected sternotomy wound following coronary artery bypass surgery. The rupture of the right ventricle occurred despite an early wound debridement and the use of negative pressure wound therapy on the sternum that did not provide sufficient stability to the sternum after the sternal wires were removed. The rupture resulted in a major bleeding but by establishing emergent cardiopulmonary bypass, the patient was saved.
C1 [Thorsteinsson, David T.; Geirsson, Arnar; Gudbjartsson, Tomas] Landspitali Univ Hosp, Dept Cardiothorac Surg, Reykjavik, Iceland.
   [Valsson, Felix] Landspitali Univ Hosp, Dept Anesthesia & Intens Care, Reykjavik, Iceland.
   [Geirsson, Arnar] Yale Univ, Sect Cardiac Surg, New Haven, CT USA.
   [Gudbjartsson, Tomas] Univ Iceland, Fac Med, Reykjavik, Iceland.
C3 Landspitali National University Hospital; Landspitali National
   University Hospital; Yale University; University of Iceland
RP Gudbjartsson, T (通讯作者)，Landspitali Univ Hosp, Dept Cardiothorac Surg, Reykjavik, Iceland.
EM tomasgud@landspitali.is
RI Thorsteinsson, David/JFB-6115-2023; Geirsson, Arnar/S-4735-2019
OI Thorsteinsson, David/0009-0004-1043-1733; 
CR Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
   Khoynezhad A, 2004, J CARDIAC SURG, V19, P74, DOI 10.1111/j.0886-0440.2004.04015.x
   Sartipy U, 2006, ANN THORAC SURG, V82, P1110, DOI 10.1016/j.athoracsur.2006.01.060
   Sjögren J, 2011, INTERACT CARDIOV TH, V12, P117, DOI 10.1510/icvts.2010.252668
   Yellin A, 2003, J THORAC CARDIOV SUR, V125, P554, DOI 10.1067/mtc.2003.31
NR 5
TC 7
Z9 11
U1 0
U2 2
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD MAY
PY 2013
VL 16
IS 5
BP 708
EP 709
DI 10.1093/icvts/ivt004
PG 2
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 132UX
UT WOS:000318095300042
PM 23357524
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Facchin, F
   Bassetto, F
   Vindigni, V
AF Facchin, Federico
   Bassetto, Franco
   Vindigni, Vincenzo
TI Invited Response on: Comment on "The Role of Portable Incisional
   Negative Pressure Wound Therapy (piNPWT) in Reducing Local Complications
   of Post-bariatric Brachioplasty: A Case-Control Study"
SO AESTHETIC PLASTIC SURGERY
LA English
DT Editorial Material
ID SINGLE-SURGEON; PANNICULECTOMIES
C1 [Facchin, Federico; Bassetto, Franco; Vindigni, Vincenzo] Univ Padua, Dept Neurosci, Plast & Reconstruct Surg Unit, Via Nicolo Giustininani 2, I-35128 Padua, Italy.
C3 University of Padua
RP Facchin, F (通讯作者)，Univ Padua, Dept Neurosci, Plast & Reconstruct Surg Unit, Via Nicolo Giustininani 2, I-35128 Padua, Italy.
EM federicofacchin@yahoo.it
RI Facchin, Federico/GLN-4990-2022; Vindigni, Vincenzo/K-5059-2016
OI Facchin, Federico/0000-0002-6695-1103; 
CR Abatangelo S, 2018, OBES SURG, V28, P2096, DOI 10.1007/s11695-018-3279-8
   Tran BNN, 2019, J SURG RES, V241, P63, DOI 10.1016/j.jss.2019.03.033
   Dragu A, 2011, OBES SURG, V21, P1781, DOI 10.1007/s11695-010-0328-3
   Facchin F, 2021, AESTHET PLAST SURG, V45, P1653, DOI 10.1007/s00266-020-02122-1
   Botero AG, 2017, ANN PLAS SURG, V79, P293, DOI 10.1097/SAP.0000000000001109
   Hammond DC, 2019, PLAST RECONSTR SURG, V144, P847, DOI 10.1097/PRS.0000000000006018
   Marchica P, 2022, J PLAST SURG HAND SU, V56, P326, DOI 10.1080/2000656X.2020.1788043
   Michaels J, 2011, PLAST RECONSTR SURG, V127, P1352, DOI 10.1097/PRS.0b013e3182063144
   Patel AA, 2020, PLAST RECONSTR SURG, V146, P390, DOI 10.1097/PRS.0000000000007026
   Pong A, 2020, PLAST RECONSTR SURG, V146, P398, DOI 10.1097/PRS.0000000000007039
NR 10
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0364-216X
EI 1432-5241
J9 AESTHET PLAST SURG
JI Aesthet. Plast. Surg.
PD FEB
PY 2022
VL 46
IS 1
BP 550
EP 551
DI 10.1007/s00266-021-02453-7
EA JUL 2021
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA YX3GN
UT WOS:000672115600003
PM 34241665
DA 2026-07-24
ER

PT J
AU Marlin, AE
   Robinson, S
AF Marlin, Arthur E.
   Robinson, Shenandoah
TI Community-Associated Methicillin-Resistant Staphylococcus
   Aureus-Infected Chronic Scalp Wound With Exposed Dura in a
   10-Year-Old Boy: Vacuum-Assisted Closure Is a Feasible Option: Case
   Report COMMENTS
SO NEUROSURGERY
LA English
DT Editorial Material
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-396X
J9 NEUROSURGERY
JI Neurosurgery
PD MAY
PY 2011
VL 68
IS 5
BP E1484
EP E1484
PG 1
WC Clinical Neurology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA 746GE
UT WOS:000289230300007
DA 2026-07-24
ER

PT J
AU Faust, E
   Kim, E
AF Faust, Elizabeth
   Kim, Esther
TI DEVELOPMENT OF A SOFT TISSUE RECONSTRUCTIVE LADDER IN TRAUMA PATIENTS TO
   IMPROVE PATIENT AND HEALTH CARE OUTCOMES WITH THE USE OF
   NEGATIVE-PRESSURE WOUND THERAPY SYSTEMS AND CELLULAR TISSUE PRODUCTS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
EM elizabeth.faust@towerhealth.org; esther.kim@towerhealth.org
CR Eriksson E, 2022, WOUND REPAIR REGEN, V30, P156, DOI 10.1111/wrr.12994
   Krost William S, 2008, EMS Mag, V37, P67
   Sartelli M, 2022, WORLD J EMERG SURG, V17, DOI 10.1186/s13017-022-00406-2
NR 3
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2023
VL 50
IS 3
SU S
MA PI85
BP S56
EP S56
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA S6IO9
UT WOS:001072181900123
DA 2026-07-24
ER

PT J
AU Greer, S
   Kasabian, A
   Thorne, C
   Borud, L
   Sims, CD
   Hsu, M
AF Greer, S
   Kasabian, A
   Thorne, C
   Borud, L
   Sims, CD
   Hsu, M
TI The use of a subatmospheric pressure dressing to salvage a gustilo grade
   IIIB open tibial fracture with concomitant osteomyelitis to avert a free
   flap
SO ANNALS OF PLASTIC SURGERY
LA English
DT Letter
ID VACUUM-ASSISTED CLOSURE; WOUND CONTROL
C1 NYU, Med Ctr, Inst Reconstruct Plast Surg, New York, NY 10016 USA.
   NYU, Med Ctr, Dept Gen Surg, New York, NY 10016 USA.
C3 New York University; New York University
RP Kasabian, A (通讯作者)，NYU, Med Ctr, Inst Reconstruct Plast Surg, 550 1st Ave, New York, NY 10016 USA.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   COLE JD, 1995, CLIN ORTHOP RELAT R, P84
   KASABIAN KK, 1997, GRABB SMITHS PLASTIC, P1031
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Thordarson DB, 1997, FOOT ANKLE INT, V18, P151, DOI 10.1177/107110079701800307
NR 5
TC 15
Z9 22
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 USA
SN 0148-7043
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD DEC
PY 1998
VL 41
IS 6
BP 687
EP 687
DI 10.1097/00000637-199812000-00022
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 147DT
UT WOS:000077473500025
PM 9869150
DA 2026-07-24
ER

PT J
AU Huang, CC
   Yang, MJ
   Zhang, ZG
   Chang, IL
AF Huang, Ching-Cheng
   Yang, Meng-Jen
   Zhang, Zhiguo
   Chang, Ing-Lin
TI Preclinical Evaluation and Characteristics of New Designed Anti-Adhesion
   Extra Thin Polyvinyl Alcohol Foam Dressings Derived from a Super Clean
   Air-Foaming Process for Negative Pressure Wound Therapy in Orthopedics
SO BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
LA English
DT Meeting Abstract
C1 [Huang, Ching-Cheng] Ming Chuan Univ, Dept Biomed Engn, Taoyuan, Taiwan.
   [Huang, Ching-Cheng; Yang, Meng-Jen] PARSD Biomed Mat Res Ctr, Changzhou, Jiangsu, Peoples R China.
   [Zhang, Zhiguo] Hohai Univ, Coll Mech & Elect Engn, Jiangsu Key Lab Special Robot Technol, Nanjing, Jiangsu, Peoples R China.
   [Chang, Ing-Lin] Changhua Christian Hosp, Dept Orthopaed, Changhua, Taiwan.
C3 Ming Chuan University; Hohai University; Changhua Christian Hospital
RI HUANG, CHING-CHENG/AFV-1816-2022
FU Taiwan PARSD Pharm. Tech. Ltd Co.
FX Authors would like to acknowledge the Taiwan PARSD Pharm. Tech. Ltd Co.
   for financial and technical supports. The authors also thank for
   technical assistances of C.-H. Shen.
NR 0
TC 0
Z9 0
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-7835
EI 1742-7843
J9 BASIC CLIN PHARMACOL
JI Basic Clin. Pharmacol. Toxicol.
PD APR
PY 2019
VL 124
SU 3
SI SI
MA 020
BP 15
EP 15
PG 1
WC Pharmacology & Pharmacy; Toxicology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pharmacology & Pharmacy; Toxicology
GA HU2HA
UT WOS:000465090800021
DA 2026-07-24
ER

PT J
AU Joyce, MR
   Dietz, DW
AF Joyce, Myles R.
   Dietz, David W.
TI Management of Complex Gastrointestinal Fistula
SO CURRENT PROBLEMS IN SURGERY
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; ABDOMINAL-WALL DEFECTS; POUCH-ANAL ANASTOMOSIS;
   OF-THE-LITERATURE; ENTEROCUTANEOUS FISTULA; RESTORATIVE PROCTOCOLECTOMY;
   CROHNS-DISEASE; SURGICAL-MANAGEMENT; LAPAROSCOPIC RESECTION;
   AORTOENTERIC FISTULA
C1 [Joyce, Myles R.; Dietz, David W.] Cleveland Clin, Dept Colorectal Surg, Cleveland, OH 44106 USA.
   [Dietz, David W.] Washington Univ, Sch Med, St Louis, MO USA.
C3 Cleveland Clinic Foundation; Washington University (WUSTL)
RP Joyce, MR (通讯作者)，Cleveland Clin, Dept Colorectal Surg, Cleveland, OH 44106 USA.
RI Dietz, David/J-9458-2015
CR Agrawal Vivek, 2003, Trop Gastroenterol, V24, P87
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   Carbonell AM, 2005, SURG ENDOSC, V19, P430, DOI 10.1007/s00464-004-8810-4
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   Raval MJ, 2007, ANN SURG, V246, P763, DOI 10.1097/SLA.0b013e31814539b1
   Reilingh TSD, 2007, BRIT J SURG, V94, P791, DOI 10.1002/bjs.5817
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NR 121
TC 28
Z9 33
U1 0
U2 3
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0011-3840
EI 1535-6337
J9 CURR PROB SURG
JI Curr. Probl. Surg.
PD MAY
PY 2009
VL 46
IS 5
BP 378
EP 430
DI 10.1067/j.cpsurg.2008.12.005
PG 53
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 432HR
UT WOS:000265124600002
PM 19328884
DA 2026-07-24
ER

PT J
AU Chetter, I
   Arundel, C
AF Chetter, Ian
   Arundel, Catherine
TI A pragmatic multicentre randomised controlled trial to assess the
   clinical and cost-effectiveness of negative pressure wound therapy
   versus usual care for surgical wounds healing by secondary intention
   (SWHSI 2)
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Meeting Abstract
C1 [Chetter, Ian] Univ Hull, Kingston Upon Hull, England.
   [Chetter, Ian] Hull York Med Sch, Kingston Upon Hull, England.
   [Chetter, Ian] Hull Univ Teaching Hosp NHS Trust, Kingston Upon Hull, England.
   [Arundel, Catherine] Univ York, York, England.
C3 University of Hull; University of York - UK; University of Hull;
   University of York - UK
NR 0
TC 0
Z9 0
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD AUG
PY 2025
VL 112
SU _13
SI SI
MA SP4.01
AR znaf166048
DI 10.1093/bjs/znaf166.048
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 6RQ0K
UT WOS:001560368700001
DA 2026-07-24
ER

PT J
AU Deschka, H
   Machner, M
   Wimmer-Greinecker, G
AF Deschka, Heinz
   Machner, Matthias
   Wimmer-Greinecker, Gerhard
TI Presternal False Aneurysm Due to Osseous Arrosion of the Right Ventricle
SO THORACIC AND CARDIOVASCULAR SURGEON
LA English
DT Article
DE aneurysm; myocardial injury (includes blunt penetrating and iatrogenic);
   sternum; wound healing
ID VACUUM-ASSISTED CLOSURE; STERNAL INFECTION; CARDIAC-SURGERY; RUPTURE
AB Right ventricular rupture after open heart surgery is a rare but severe postoperative complication. In most cases, right ventricular bleeding is associated with mediastinitis and either directly caused by inflammatory processes or iatrogenically through penetration of dehiscent sternal edges or vacuum-assisted closure therapy. We describe a case of right ventricular rupture due to osseous arrosion in a closed chest in the absence of mediastinitis which led to the creation of a massive presternal false aneurysm.
C1 [Deschka, Heinz; Machner, Matthias; Wimmer-Greinecker, Gerhard] Heart & Vessel Ctr Bad Bevensen, Dept Cardiothorac Surg, D-29549 Bad Bevensen, Germany.
RP Deschka, H (通讯作者)，Heart & Vessel Ctr Bad Bevensen, Dept Cardiothorac Surg, Romstedterstr 25, D-29549 Bad Bevensen, Germany.
EM deschkaheinz@hotmail.com
CR Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
   Bapat V, 2008, J CARDIAC SURG, V23, P227, DOI 10.1111/j.1540-8191.2008.00595.x
   Khoynezhad A, 2004, J CARDIAC SURG, V19, P74, DOI 10.1111/j.0886-0440.2004.04015.x
   Niclauss L, 2010, INTERACT CARDIOV TH, V10, P470, DOI 10.1510/icvts.2009.223891
   Sartipy U, 2006, ANN THORAC SURG, V82, P1110, DOI 10.1016/j.athoracsur.2006.01.060
   Yellin A, 2003, J THORAC CARDIOV SUR, V125, P554, DOI 10.1067/mtc.2003.31
NR 6
TC 0
Z9 0
U1 0
U2 2
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0171-6425
EI 1439-1902
J9 THORAC CARDIOV SURG
JI Thorac. Cardiovasc. Surg.
PD APR
PY 2013
VL 61
IS 3
BP 261
EP 263
DI 10.1055/s-0032-1327761
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 120MY
UT WOS:000317175800016
PM 23258758
DA 2026-07-24
ER

PT J
AU Birnbaum, DJ
   D'Journo, XB
   Casanova, D
   Thomas, PA
AF Birnbaum, David J.
   D'Journo, Xavier Benoit
   Casanova, Dominique
   Thomas, Pascal A.
TI Necrotizing fasciitis of the chest wall
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Necrotizing fasciitis; Chest wall; Group A beta-haemolytic
   streptococcus; Vacuum-assisted closure
AB Necrotizing fasciitis (NF) is an uncommon infection caused by microorganisms called `flesh eating bacteria'. It remains a life-threatening condition associated with high mortality rate. Its location to the chest wall is exceptional. Herein, we report the case of a 39-year-old female, without comorbidity, presenting a NF of the chest wall complicating an empyema. We describe the surgical management with a three-step procedure: antibiotherapy-debridement, vacuum-assisted closure and delayed surgical reconstruction. (C) 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.
C1 Univ Mediterranean, Dept Thorac Surg, Hop St Marguerite, Marseille, France.
   Assistance Publ Hop Marseille, Marseille, France.
C3 Aix-Marseille Universite; Assistance Publique-Hopitaux de Marseille;
   Aix-Marseille Universite; Assistance Publique-Hopitaux de Marseille
RP Thomas, PA (通讯作者)，CHU Sud, Dept Chirurg Thorac & Malad Oesophage, Hop St Marguerite, 270 Bd Ste Marguerite, F-13274 Marseille 9, France.
EM Pascal-alexandre.Thomas@mail.ap-hm.fr
RI D'journo, Xavier Benoit/AAJ-4457-2021; Birnbaum, David/Z-1563-2019;
   Thomas, Pascal/L-3355-2019
OI D'journo, Xavier Benoit/0000-0001-6747-4583; Thomas,
   Pascal/0000-0002-3305-6989
CR Barbosa RF, 2006, MICROSURG, V26, P519, DOI 10.1002/micr.20280
   Kalkat M S, 2003, Interact Cardiovasc Thorac Surg, V2, P358, DOI 10.1016/S1569-9293(03)00050-1
   Konstantinov IE, 2008, ANN THORAC SURG, V86, P1973, DOI 10.1016/j.athoracsur.2008.05.004
   Safran DB, 2001, ANN THORAC SURG, V72, P1362, DOI 10.1016/S0003-4975(00)02588-1
   Urschel JD, 1997, ANN THORAC SURG, V64, P276, DOI 10.1016/S0003-4975(97)00514-6
NR 5
TC 11
Z9 12
U1 0
U2 3
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
EI 1569-9285
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD MAR
PY 2010
VL 10
IS 3
BP 483
EP 484
DI 10.1510/icvts.2009.222323
PG 2
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA V25LY
UT WOS:000208480700049
PM 20019031
OA Bronze
DA 2026-07-24
ER

PT J
AU Pines, G
   Lazar, L
   Mashni, I
   Miller, R
   Gal, E
AF Pines, Guy
   Lazar, Li Or
   Mashni, Ibrahim
   Miller, Rafael
   Gal, Eyal
TI Modified Endoscopic Vacuum-Assisted Closure (EVAC) for Esophageal
   Perforation: a Promising and Simplified Technique - Report of Three
   Patients
SO INDIAN JOURNAL OF SURGERY
LA English
DT Article
DE Esophageal perforation; Stent; Endoscopic VAC; Mediastinitis
ID THERAPY; DRAINAGE; RUPTURE; STENT
AB Intrathoracic esophageal perforation is a devastating event bearing high mortality rates. Prompt recognition and aggressive treatment are key. Traditionally, most patients required surgical treatment, but recently, endoscopic techniques, mainly endoscopic vacuum-assisted closure (EVAC), have been recognized as a valuable alternative in selected patients. Herein, we describe a novel technique in which a nasogastric tube (NGT) was placed endoscopically into a mediastinal abscess and covered with a self-expanding metal stent to treat esophageal defects in three patients.
C1 [Pines, Guy; Lazar, Li Or; Mashni, Ibrahim] Kaplan Med Ctr, Dept Thorac Surg, Rehovot, Israel.
   [Pines, Guy; Lazar, Li Or; Mashni, Ibrahim; Miller, Rafael; Gal, Eyal] Hebrew Univ Jerusalem, Fac Med, Rehovot, Israel.
   [Pines, Guy; Miller, Rafael] Kaplan Med Ctr, Dept Surg, Rehovot, Israel.
   [Gal, Eyal] Kaplan Med Ctr, Dept Gastroenterol & Liver Dis, Rehovot, Israel.
C3 Hebrew University of Jerusalem; Kaplan Medical Center; Hebrew University
   of Jerusalem; Hebrew University of Jerusalem; Kaplan Medical Center;
   Hebrew University of Jerusalem; Kaplan Medical Center
RP Pines, G (通讯作者)，Kaplan Med Ctr, Dept Thorac Surg, Rehovot, Israel.; Pines, G (通讯作者)，Hebrew Univ Jerusalem, Fac Med, Rehovot, Israel.; Pines, G (通讯作者)，Kaplan Med Ctr, Dept Surg, Rehovot, Israel.
EM Guypi@clalit.org.il
RI Pines, Guy/A-4251-2017
OI Pines, Guy/0000-0003-2923-660X
CR Aziz M, 2021, ENDOSC INT OPEN, V09, pE1371, DOI 10.1055/a-1508-5947
   Bi YH, 2019, RADIOL MED, V124, P1253, DOI 10.1007/s11547-019-01074-0
   Han XW, 2016, J SURG ONCOL, V114, P725, DOI 10.1002/jso.24384
   de Moura DTH, 2019, WORLD J GASTRO ENDOS, V11, P329, DOI 10.4253/wjge.v11.i5.329
   Kuehn F, 2016, J GASTROINTEST SURG, V20, P237, DOI 10.1007/s11605-015-3044-4
   Loske G, 2011, ENDOSCOPY, V43, P540, DOI 10.1055/s-0030-1256345
   Newton NJ, 2017, DIS ESOPHAGUS, V30, DOI 10.1111/dote.12531
   Pines G, 2018, J LAPAROENDOSC ADV S, V28, P33, DOI 10.1089/lap.2017.0318
   Sharp G, 2021, ANZ J SURG, V91, P537, DOI 10.1111/ans.16581
   Sohda M, 2020, ESOPHAGUS-TOKYO, V17, P230, DOI 10.1007/s10388-020-00744-7
   Wu G, 2017, J TRAUMA ACUTE CARE, V82, P141, DOI 10.1097/TA.0000000000001272
   Yu LL, 2018, J INT MED RES, V46, P1528, DOI 10.1177/0300060517752995
NR 12
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER INDIA
PI NEW DELHI
PA 7TH FLOOR, VIJAYA BUILDING, 17, BARAKHAMBA ROAD, NEW DELHI, 110 001,
   INDIA
SN 0972-2068
EI 0973-9793
J9 INDIAN J SURG
JI Indian J. Surg
PD OCT
PY 2023
VL 85
IS SUPPL 2
SU 2
SI SI
BP 597
EP 601
DI 10.1007/s12262-023-03793-1
EA APR 2023
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CA3A1
UT WOS:000978061300001
DA 2026-07-24
ER

PT J
AU Tang, ATM
   Ohri, SK
   Haw, MP
AF Tang, ATM
   Ohri, SK
   Haw, MP
TI Novel application of vacuum assisted closure technique to the treatment
   of sternotomy wound infection
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article
DE negative pressure therapy; sternal dehiscence; mediastinitis; treatment
AB Infection of the sternotomy wound is a potentially devastating and sometimes lethal complication following cardiac surgery. Established treatment may involve a combination of debridement, packing, delayed closure, plastic reconstruction, re-wiring and irrigation dependent on the severity of infection. Vacuum assisted closure, originally adopted for the treatment of non-healing wounds, has recently gained popularity among various surgical specialities in managing complex wound infection. Here we describe this novel technique of managing postoperative sternal wound infection. (C) 2000 Elsevier Science B.V. All rights reserved.
C1 Southampton Gen Hosp, Wessex Reg Thorac & Cardiac Unit, Dept Cardiac Surg, Southampton SO16 6YD, Hants, England.
C3 University of Southampton
RP Tang, ATM (通讯作者)，Southampton Gen Hosp, Wessex Reg Thorac & Cardiac Unit, Dept Cardiac Surg, Tremona Rd, Southampton SO16 6YD, Hants, England.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Davydov Iu A, 1994, Khirurgiia (Mosk), P7
   Davydov Iu A, 1992, Khirurgiia (Mosk), P21
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Raudat CW, 1997, AM SURGEON, V63, P238
NR 6
TC 87
Z9 102
U1 0
U2 4
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1010-7940
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD APR
PY 2000
VL 17
IS 4
BP 482
EP 484
DI 10.1016/S1010-7940(00)00349-3
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 311WT
UT WOS:000086909700037
PM 10773574
OA Bronze
DA 2026-07-24
ER

PT J
AU Lygrisse, KA
   Teo, G
   Singh, V
   Muthusamy, N
   Schwarzkopf, R
   Long, W
AF Lygrisse, Katherine A.
   Teo, Greg
   Singh, Vivek
   Muthusamy, Nishanth
   Schwarzkopf, Ran
   Long, William
TI Comparison of silver-embedded occlusive dressings and negative pressure
   wound therapy following total joint arthroplasty in high BMI patients: a
   randomized controlled trial (Jul, 10.1007/s00402-022-04530-1, 2022)
SO ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
LA English
DT Correction
C1 [Lygrisse, Katherine A.] Huntington Hosp, Zucker Sch Med Hofstra Northwell, Dept Orthoped Surg, 270 Pk Ave, Huntington, NY 11743 USA.
   [Teo, Greg; Long, William] Hosp Special Surgeries, Dept Orthoped Surg, 541 East 71st St,7th Fl, New York, NY 10021 USA.
   [Singh, Vivek; Muthusamy, Nishanth; Schwarzkopf, Ran] NYU, Langone Hlth, Dept Orthoped Surg, 301 East 17th St,15th Fl Suite 1518, New York, NY 10003 USA.
   [Muthusamy, Nishanth] NYU, Langone Hlth, Dept Orthoped Surg, Div Adult Reconstruct Surg, 301 East 17th St, New York, NY 10003 USA.
C3 Northwell Health; New York University; New York University
RP Muthusamy, N (通讯作者)，NYU, Langone Hlth, Dept Orthoped Surg, 301 East 17th St,15th Fl Suite 1518, New York, NY 10003 USA.; Muthusamy, N (通讯作者)，NYU, Langone Hlth, Dept Orthoped Surg, Div Adult Reconstruct Surg, 301 East 17th St, New York, NY 10003 USA.
EM nmuthusamy13@gmail.com
OI Muthusamy, Nishanth/0000-0003-1227-7093
CR Lygrisse KA, 2023, ARCH ORTHOP TRAUM SU, V143, P2989, DOI 10.1007/s00402-022-04530-1
NR 1
TC 0
Z9 0
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0936-8051
EI 1434-3916
J9 ARCH ORTHOP TRAUM SU
JI Arch. Orthop. Trauma Surg.
PD JUN
PY 2023
VL 143
IS 6
BP 2997
EP 2997
DI 10.1007/s00402-022-04552-9
EA JUL 2022
PG 1
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA G9CW0
UT WOS:000826261000001
PM 35842883
OA Bronze
DA 2026-07-24
ER

PT J
AU Kairinos, N
   Hudson, DA
   Solomons, M
AF Kairinos, Nicolas
   Hudson, Donald Anthony
   Solomons, Michael
TI Letter: The influence of different sizes and types of wound fillers on
   wound contraction and tissue pressure during negative pressure wound
   therapy
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Letter
ID MICROVASCULAR BLOOD-FLOW; ASSISTED CLOSURE THERAPY; POLYURETHANE-FOAM;
   GAUZE
C1 [Kairinos, Nicolas; Hudson, Donald Anthony] Groote Schuur Hosp, Dept Plast & Reconstruct Surg, ZA-7925 Cape Town, South Africa.
   [Solomons, Michael] Univ Cape Town, Groote Schuur Hosp, Dept Martin Singer Hand Unit, ZA-7925 Cape Town, South Africa.
C3 University of Cape Town; University of Cape Town
RP Kairinos, N (通讯作者)，Groote Schuur Hosp, Dept Plast & Reconstruct Surg, H53 Old Main Bldg Observ,Main Rd, ZA-7925 Cape Town, South Africa.
EM nickykairinos@gmail.com
CR Anesäter E, 2011, INT WOUND J, V8, P336, DOI 10.1111/j.1742-481X.2011.00790.x
   Borgquist O, 2010, ANN PLAS SURG, V64, P789, DOI 10.1097/SAP.0b013e3181ba578a
   Borgquist O, 2010, OSTOMY WOUND MANAG, V56, P60
   Borgquist O, 2010, PLAST RECONSTR SURG, V125, P502, DOI 10.1097/PRS.0b013e3181c82e1f
   Kairinos N, 2010, J PLAST RECONSTR AES, V63, P174, DOI 10.1016/j.bjps.2008.08.037
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P601, DOI 10.1097/PRS.0b013e318196b97b
   Malmsjö M, 2011, INTERACT CARDIOV TH, V12, P349, DOI 10.1510/icvts.2010.249078
   Malmsjö M, 2009, ANN PLAS SURG, V63, P676, DOI 10.1097/SAP.0b013e31819ae01b
   Malmsjö M, 2009, WOUND REPAIR REGEN, V17, P200, DOI 10.1111/j.1524-475X.2009.00461.x
   Sjögren J, 2003, ANN THORAC SURG, V75, P1311, DOI 10.1016/S0003-4975(02)04570-8
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
NR 12
TC 8
Z9 9
U1 0
U2 1
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1742-4801
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2011
VL 8
IS 6
BP 656
EP 657
DI 10.1111/j.1742-481X.2011.00825.x
PG 2
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 854AL
UT WOS:000297466800013
PM 21848729
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Müller-Seubert, W
   Roth, S
   Hauck, T
   Arkudas, A
   Horch, RE
   Ludolph, I
AF Muller-Seubert, Wibke
   Roth, Sascha
   Hauck, Theresa
   Arkudas, Andreas
   Horch, Raymund E.
   Ludolph, Ingo
TI Response to the letter to the editor 'Novel imaging methods reveal
   positive impact of topical negative pressure application on tissue
   perfusion in an in-vivo skin model'
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Letter
ID VACUUM-ASSISTED CLOSURE
C1 [Muller-Seubert, Wibke; Roth, Sascha; Hauck, Theresa; Arkudas, Andreas; Horch, Raymund E.; Ludolph, Ingo] Friedrich Alexander Univ Erlangen Nuernberg FAU, Dept Plast & Hand Surg & Lab Tissue Engn & Regene, Univ Hosp Erlangen, Erlangen, Germany.
C3 University of Erlangen Nuremberg
RP Müller-Seubert, W (通讯作者)，Krankenhaus Str 12, D-91054 Erlangen, Germany.
EM wibke.mueller-seubert@uk-erlangen.de
RI Horch, Raymund E/H-8128-2019; Arkudas, Andreas/AAQ-6745-2021
OI Horch, Raymund E/0000-0002-6561-2353; Arkudas,
   Andreas/0000-0002-2473-5816
CR Atkins BZ, 2011, INT WOUND J, V8, P56, DOI 10.1111/j.1742-481X.2010.00743.x
   CHERRY GW, 1983, PLAST RECONSTR SURG, V72, P680, DOI 10.1097/00006534-198311000-00018
   Daigle P, 2013, WOUND REPAIR REGEN, V21, P498, DOI 10.1111/wrr.12052
   MARKS MW, 1986, J TRAUMA, V26, P913, DOI 10.1097/00005373-198610000-00009
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Muller-Seubert W, 2021, INT WOUND J, V18, P932, DOI 10.1111/iwj.13639
   Patmo ASP, 2014, ADV WOUND CARE, V3, P383, DOI 10.1089/wound.2013.0510
   Sogorski A, 2018, J TISSUE VIABILITY, V27, P267, DOI 10.1016/j.jtv.2018.08.004
   Timmers MS, 2005, ANN PLAS SURG, V55, P665, DOI 10.1097/01.sap.0000187182.90907.3d
NR 9
TC 4
Z9 4
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2021
VL 18
IS 6
BP 942
EP 943
DI 10.1111/iwj.13683
EA SEP 2021
PG 2
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA XM0ZU
UT WOS:000693738400001
PM 34498375
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Gendics, C
   Schwartz, J
   Avdagic, E
   Lantis, J
AF Gendics, Cynthia
   Schwartz, Jamie
   Avdagic, Ema
   Lantis, John, II
TI ROLE OF THE SENIOR NURSE IN IDENTIFYING PATIENTS THAT MAY BENEFIT FROM
   NEGATIVE PRESSURE WOUND THERAPY WITH INSTILLATION AS AN OPTION TO
   ENHANCE CLOSURE IN DIFFICULT LOWER LEG AND FOOT WOUNDS
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
EM cgendics@chpnet.org; jschwartz@chpnet.org; emaavdagic2377@gmail.com;
   JLantis@chpnet.org
CR Gabriel A, 2012, INT WOUND J, V9, P25, DOI 10.1111/j.1742-481X.2012.01014.x
   Wolvos T, 2013, WOUNDS, V25, P75
NR 2
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2014
VL 41
SU 3
BP S12
EP S13
PG 2
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA AH2XY
UT WOS:000335986600032
DA 2026-07-24
ER

PT J
AU Koch, GE
   Abbasi, B
   Agoubi, L
   Breyer, BN
   Clark, N
   Dick, BP
   Friedrich, JB
   Hampson, LA
   Hernandez, A
   Maine, R
   Osterberg, EC
   Teal, L
   Woodle, T
   Hagedorn, JC
AF Koch, George E.
   Abbasi, Behzad
   Agoubi, Lauren
   Breyer, Benjamin N.
   Clark, Nina
   Dick, Brian P.
   Friedrich, Jeffrey B.
   Hampson, Lindsay A.
   Hernandez, Alexandra
   Maine, Rebecca
   Osterberg, E. Charles
   Teal, Lindsey
   Woodle, Tarah
   Hagedorn, Judith C.
TI Multidisciplinary management in Fournier's gangrene
SO CURRENT PROBLEMS IN SURGERY
LA English
DT Review
ID SOFT-TISSUE INFECTIONS; HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED
   CLOSURE; PRESSURE WOUND THERAPY; LOTUS PETAL FLAP; NECROTIZING
   FASCIITIS; SEVERITY INDEX; RISK-FACTORS; RETROSPECTIVE ANALYSIS;
   RECONSTRUCTION
C1 [Koch, George E.; Hagedorn, Judith C.] Univ Washington, Dept Urol, Ninth & Jefferson Bldg,908 Jefferson St,9th Floor, Seattle, WA 98104 USA.
   [Abbasi, Behzad; Dick, Brian P.; Hampson, Lindsay A.] Univ Calif San Francisco, Dept Urol, San Francisco, CA USA.
   [Agoubi, Lauren; Clark, Nina; Hernandez, Alexandra] Univ Washington, Dept Surg, Seattle, WA USA.
   [Breyer, Benjamin N.] Univ Calif San Francisco, Dept Urol, San Francisco, CA USA.
   [Breyer, Benjamin N.] Univ Calif San Francisco, Dept Epidemiol, San Francisco, CA USA.
   [Breyer, Benjamin N.] Univ Calif San Francisco, Dept Biostat, San Francisco, CA USA.
   [Friedrich, Jeffrey B.] Univ Washington, Dept Surg, Div Plast Surg, Seattle, WA USA.
   [Maine, Rebecca; Osterberg, E. Charles; Teal, Lindsey] Dell Med Sch, Dept Surg & Perioperat Care, Austin, TX USA.
   [Woodle, Tarah] Brooke Army Med Ctr, Dept Surg, Ft Sam Houston, TX USA.
C3 University of Washington; University of Washington Seattle; University
   of California System; University of California San Francisco; University
   of Washington; University of Washington Seattle; University of
   California System; University of California San Francisco; University of
   California System; University of California San Francisco; University of
   California System; University of California San Francisco; University of
   Washington; University of Washington Seattle; United States Department
   of Defense; United States Army; Brooke Army Medical Center
RP Koch, GE (通讯作者)，Univ Washington, Dept Urol, Ninth & Jefferson Bldg,908 Jefferson St,9th Floor, Seattle, WA 98104 USA.
EM Kochge@uw.edu
RI Hampson, Lindsay/GZL-8235-2022; Hernandez, Alexana/AAJ-8735-2020;
   Abbasi, Behzad/PLD-2046-2026; Clark, Nina/MHQ-3799-2025
OI Hampson, Lindsay/0000-0002-0740-7984; Hernandez,
   Alexana/0000-0002-4012-6164; Abbasi, Behzad/0000-0002-7175-9984;
   Friedrich, Jeffrey/0000-0002-5245-9708; Clark, Nina/0000-0002-1573-554X
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NR 206
TC 7
Z9 8
U1 0
U2 8
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0011-3840
EI 1535-6337
J9 CURR PROB SURG
JI Curr. Probl. Surg.
PD JUL
PY 2024
VL 61
IS 7
AR 101499
DI 10.1016/j.cpsurg.2024.101499
EA JUN 2024
PG 47
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WM5S0
UT WOS:001255307000001
PM 38879239
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Lygrisse, KA
   Teo, G
   Singh, V
   Muthusamy, N
   Schwarzkopf, R
   Long, WJ
AF Lygrisse, Katherine A.
   Teo, Greg
   Singh, Vivek
   Muthusamy, Nishanth
   Schwarzkopf, Ran
   Long, William John
TI Comparison of silver-embedded occlusive dressings and negative pressure
   wound therapy following total joint arthroplasty in high BMI patients: a
   randomized controlled trial (Nov, 10.1007/s00402-022-04530-1, 2022)
SO ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
LA English
DT Correction
C1 [Lygrisse, Katherine A.] Zucker Sch Med Hofstra Northwell, Huntington Hosp, Dept Orthped Surg, 270 Pk Ave, Huntington, NY 11743 USA.
   [Teo, Greg; Long, William John] Hosp Special Surgeries, Dept Orthped Surg, 541 East 71st St,7th Fl, New York, NY 10021 USA.
   [Singh, Vivek; Muthusamy, Nishanth; Schwarzkopf, Ran] NYU Langone Hlth, Dept Orthped Surg, 301 East 17th St,15th Fl Suite 1518, New York, NY 10003 USA.
   [Muthusamy, Nishanth] NYU Langone Hlth, Dept Orthped Surg, Div Adult Reconstruct Surg, 301 East 17th St, New York, NY 10003 USA.
C3 Northwell Health; NYU Langone Medical Center; NYU Langone Medical Center
RP Muthusamy, N (通讯作者)，NYU Langone Hlth, Dept Orthped Surg, 301 East 17th St,15th Fl Suite 1518, New York, NY 10003 USA.; Muthusamy, N (通讯作者)，NYU Langone Hlth, Dept Orthped Surg, Div Adult Reconstruct Surg, 301 East 17th St, New York, NY 10003 USA.
EM nmuthusamy13@gmail.com
OI Muthusamy, Nishanth/0000-0003-1227-7093
CR Lygrisse KA, 2023, ARCH ORTHOP TRAUM SU, V143, P2989, DOI 10.1007/s00402-022-04530-1
NR 1
TC 0
Z9 0
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0936-8051
EI 1434-3916
J9 ARCH ORTHOP TRAUM SU
JI Arch. Orthop. Trauma Surg.
PD JUL
PY 2023
VL 143
IS 7
BP 4575
EP 4575
DI 10.1007/s00402-022-04691-z
EA NOV 2022
PG 1
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA L1BH1
UT WOS:000882342200001
PM 36370161
OA Bronze
DA 2026-07-24
ER

PT J
AU Allen, D
   Schmidt, M
   Kieswetter, K
   Kendrick, R
   Stokes, B
   Robinson, T
   Locke, C
AF Allen, Diwi
   Schmidt, Marisa
   Kieswetter, Kristine
   Kendrick, Rosella
   Stokes, Ben
   Robinson, Tim
   Locke, Christopher
TI EVALUATION OF A NOVEL NEGATIVE PRESSURE WOUND THERAPY DRESSING:
   USABILITY AND PRECLINICAL STUDIES SHOW POTENTIAL BENEFITS AND EASE OF
   USE COMPARED TO STANDARD FOAM DRESSING AFTER 7 DAYS OF CONTINUOUS
   THERAPY
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Allen, Diwi; Schmidt, Marisa; Kieswetter, Kristine] R&D, San Antonio, TX USA.
   [Kendrick, Rosella; Stokes, Ben; Robinson, Tim; Locke, Christopher] R&D, Dorset, TX USA.
EM diwi.allen@acelity.com; marisa.schmidt@acelity.com;
   kris.kieswetter@acelity.com; rosella.kendrick@acelity.com;
   ben.stokes@acelity.com; tim.robinson@acelity.com;
   christopher.locke@acelity.com
NR 0
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2020
VL 47
SU 3
MA R10
BP S56
EP S56
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA MR0UY
UT WOS:000553309900134
DA 2026-07-24
ER

PT J
AU Banasiewicz, T
   Paszkowski, J
   Hermann, J
   Cwalinski, J
   Eder, P
   Stawczyk-Eder, K
   Waszak, K
   Dobrowolska, A
AF Banasiewicz, T.
   Paszkowski, J.
   Hermann, J.
   Cwalinski, J.
   Eder, P.
   Stawczyk-Eder, K.
   Waszak, K.
   Dobrowolska, A.
TI The minimal invasive surgery in combination with negative pressure wound
   therapy for perianal fistulas in Crohn's colitis lead to the fast
   introduction of the biological treatment and improve the results
SO JOURNAL OF CROHNS & COLITIS
LA English
DT Meeting Abstract
C1 [Banasiewicz, T.; Paszkowski, J.; Hermann, J.; Cwalinski, J.] Univ Med Sci, Gen Endocrinol Surg & Gastrointestinal Oncol, Poznan, Poland.
   Univ Med Sci, Dept Gastroenterol, Poznan, Poland.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1873-9946
EI 1876-4479
J9 J CROHNS COLITIS
JI J. Crohns Colitis
PD MAR
PY 2019
VL 13
SU 1
MA P363
BP S286
EP S286
DI 10.1093/ecco-jcc/jjy222.487
PG 1
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA HN9UA
UT WOS:000460544501214
OA Bronze
DA 2026-07-24
ER

PT J
AU Ubbink, DT
   Vermeulen, H
   Legemate, DA
AF Ubbink, D. T.
   Vermeulen, H.
   Legemate, D. A.
TI Comment on: "Negative Pressure Wound Therapy: a Systematic Review of
   Effectiveness and Safety", P. Vikatmaa, V. Juutilainen, P. Kuukasjarvi,
   A. Malmivaara, Eur J Vasc Endovasc Surg 2008;36(4):438-48
SO EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
LA English
DT Letter
C1 Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands.
C3 University of Amsterdam; Academic Medical Center Amsterdam
RP Ubbink, DT (通讯作者)，Univ Amsterdam, Acad Med Ctr, Meibergdreef 9,Room J1B-215, NL-1105 AZ Amsterdam, Netherlands.
EM d.ubbink@amc.nl
RI Vermeulen, Hester/P-5739-2016; Ubbink, Dirk/AAF-1266-2021
OI Vermeulen, Hester/0000-0002-0743-2979; Ubbink, Dirk/0000-0001-9398-8879
CR Murie JA, 2006, BRIT J SURG, V93, P1560, DOI 10.1002/bjs.5642
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   Ubbink DT, 2008, COCHRANE DB SYST REV, V3
   VIKATMAA P, 2008, J VASC SURG, V48, P1065
NR 4
TC 0
Z9 1
U1 0
U2 0
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 1078-5884
J9 EUR J VASC ENDOVASC
JI Eur. J. Vasc. Endovasc. Surg.
PD JUN
PY 2009
VL 37
IS 6
BP 740
EP 741
DI 10.1016/j.ejvs.2009.01.018
PG 2
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA 465LC
UT WOS:000267585100019
PM 19328731
OA Bronze
DA 2026-07-24
ER

PT J
AU Driver, VR
   Blume, PA
AF Driver, Vickie R.
   Blume, Peter A.
TI Evaluation of Wound Care and Health-Care Use Costs in Patients with
   Diabetic Foot Ulcers Treated with Negative Pressure Wound Therapy versus
   Advanced Moist Wound Therapy (vol 104, pg 147, 2014)
SO JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION
LA English
DT Correction
CR Driver VR, 2014, J AM PODIAT MED ASSN, V104, P147, DOI 10.7547/0003-0538-104.2.147
NR 1
TC 2
Z9 2
U1 0
U2 7
PU AMER PODIATRIC MED ASSOC
PI BETHESDA
PA 9312 OLD GEORGETOWN ROAD, BETHESDA, MD 20814-1621 USA
SN 8750-7315
EI 1930-8264
J9 J AM PODIAT MED ASSN
JI J. Am. Podiatr. Med. Assoc.
PD JUL-AUG
PY 2014
VL 104
IS 4
BP 374
EP 374
PG 1
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA AQ3KG
UT WOS:000342690700007
DA 2026-07-24
ER

PT J
AU Campos, D
   Hernandez, DV
   Perez, 
   Palka-Santini, M
AF Campos, D.
   Hernandez, Vega D.
   Perez, V
   Palka-Santini, M.
TI POTENTIAL BUDGET IMPACT OF NEGATIVE PRESSURE WOUND THERAPY (NPWT) VERSUS
   CONVENTIONAL WOUND TREATMENT (CWT) IN DIABETIC FOOT ULCERS (DFU),
   SURGICAL ABDOMINAL WOUNDS WITH HEALING IMPAIRMENT (SAWHI), AND TRAUMA
   WOUNDS FOR MEXICO
SO VALUE IN HEALTH
LA English
DT Meeting Abstract
C1 [Campos, D.] 3M Hlth Care, Pavas, Costa Rica.
   [Hernandez, Vega D.] 3M Hlth Care, Mexico City, DF, Mexico.
   [Perez, V] 3M Argentina SACIFIA, Escobar, Argentina.
   [Palka-Santini, M.] 3M Deutschland GmbH, Neuss, NW, Germany.
C3 3M
NR 0
TC 0
Z9 0
U1 2
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1098-3015
EI 1524-4733
J9 VALUE HEALTH
JI Value Health
PD DEC
PY 2023
VL 26
IS 12
SU S
MA EE133
BP S76
EP S76
PG 1
WC Economics; Health Care Sciences & Services; Health Policy & Services
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Business & Economics; Health Care Sciences & Services
GA EE6J4
UT WOS:001137279500327
DA 2026-07-24
ER

PT J
AU Nieto, D
   Sendagorta, E
   Rueda, JM
   Herranz, P
AF Nieto, D.
   Sendagorta, E.
   Rueda, J. M.
   Herranz, P.
TI Successful treatment with ustekinumab and vacuum-assisted closure
   therapy in recalcitrant myelodysplastic syndrome-associated pyoderma
   gangrenosum: case report and literature review
SO CLINICAL AND EXPERIMENTAL DERMATOLOGY
LA English
DT Editorial Material
ID EXPRESSION
AB Click for the corresponding questions to this CME article.
C1 [Nieto, D.; Sendagorta, E.; Rueda, J. M.; Herranz, P.] La Paz Hosp, Dept Dermatol, Madrid, Spain.
C3 Hospital Universitario La Paz
RP Nieto, D (通讯作者)，La Paz Hosp, Paseo Castellana 261, Madrid 28046, Spain.
EM dnr348@gmail.com
OI Herranz, Pedro/0000-0002-9840-6628
CR Fahmy M, 2012, AM J GASTROENTEROL, V107, P794, DOI 10.1038/ajg.2012.42
   Goldminz AM, 2012, J AM ACAD DERMATOL, V67, pE237, DOI 10.1016/j.jaad.2012.04.045
   Greb JE, 2016, DERMATOL THER, V29, P482, DOI 10.1111/dth.12387
   Guenova E, 2011, ARCH DERMATOL, V147, P1203, DOI 10.1001/archdermatol.2011.168
   Langan SM, 2012, J INVEST DERMATOL, V132, P2166, DOI 10.1038/jid.2012.130
   Marzano AV, 2016, BRIT J DERMATOL, V175, P882, DOI 10.1111/bjd.14691
   Marzano AV, 2014, CLIN EXP IMMUNOL, V178, P48, DOI 10.1111/cei.12394
   Patel F, 2015, ACTA DERM-VENEREOL, V95, P525, DOI 10.2340/00015555-2008
   Pichler M, 2017, J EUR ACAD DERMATOL, V31, pE61, DOI 10.1111/jdv.13727
NR 9
TC 18
Z9 19
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0307-6938
EI 1365-2230
J9 CLIN EXP DERMATOL
JI Clin. Exp. Dermatol.
PD JAN
PY 2019
VL 44
IS 1
BP 116
EP 119
DI 10.1111/ced.13679
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA HD0BZ
UT WOS:000452173800037
PM 29851121
OA Bronze
DA 2026-07-24
ER

PT J
AU Brisinda, G
   Chiarello, MM
AF Brisinda, Giuseppe
   Chiarello, Maria Michela
TI The impact of negative pressure wound therapy for closed surgical
   incisions on surgical site infection: A systematic review and
   meta-analysis
SO SURGERY
LA English
DT Letter
ID ABDOMINAL-WALL RECONSTRUCTION; RETROSPECTIVE COHORT ANALYSIS;
   PERIOPERATIVE COMPLICATIONS; BIOLOGIC MESH
C1 [Brisinda, Giuseppe] Univ Cattolica Sacro Cuore, Fdn Policlin Univ Agostino Gemelli IRCC, Dept Surg, Rome, Italy.
   [Chiarello, Maria Michela] San Giovanni di Dio Hosp, Gen Surg Operat Unit, Dept Surg, Crotone, Italy.
C3 Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli
RP Brisinda, G (通讯作者)，Univ Cattolica Sacro Cuore, Fdn Policlin Univ Agostino Gemelli IRCC, Dept Surg, Rome, Italy.
EM gbrisin@tin.it
RI Brisinda, Giuseppe/G-6436-2010; chiarello, MARIA MICHELA/GVS-7109-2022
OI Brisinda, Giuseppe/0000-0001-8820-9471; chiarello, MARIA
   MICHELA/0000-0003-3455-0062
FU Research Funds of Azienda Unita Sanitaria Locale-IRCCS di Reggio Emilia
FX This study was supported by the Research Funds of Azienda Unita
   Sanitaria Locale-IRCCS di Reggio Emilia.
CR Abadía P, 2021, SURG INFECT, V22, P234, DOI 10.1089/sur.2019.309
   Bakaeen FG, 2019, J THORAC CARDIOV SUR, V157, P1891, DOI 10.1016/j.jtcvs.2018.10.152
   Brisinda G, 2021, SURGERY, V169, P1257, DOI 10.1016/j.surg.2020.07.039
   Chambers LM, 2020, AM J OBSTET GYNECOL, V223, DOI 10.1016/j.ajog.2020.05.011
   Chiarello MM, 2020, INT J SURG, V76, P14, DOI 10.1016/j.ijsu.2020.02.002
   Cuomo R, 2021, J INVEST SURG, V34, P335, DOI 10.1080/08941939.2019.1616009
   Galiano RD, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001560
   Gassman A, 2015, HERNIA, V19, P273, DOI 10.1007/s10029-014-1312-y
   Latifi R, 2020, INT J SURG, V74, P94, DOI 10.1016/j.ijsu.2019.12.035
   Swanson EW, 2016, PLAST SURG-CHIR PLAS, V24, P113, DOI 10.1177/229255031602400207
NR 10
TC 3
Z9 3
U1 0
U2 2
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
EI 1532-7361
J9 SURGERY
JI Surgery
PD MAY
PY 2021
VL 169
IS 5
BP 1257
EP 1259
DI 10.1016/j.surg.2020.07.039
EA MAY 2021
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA RY1PQ
UT WOS:000647689600050
PM 32888710
DA 2026-07-24
ER

PT J
AU Pour, SM
AF Pour, Saman Mohammadi
TI Use of Negative Pressure Wound Therapy With Silver Base Dressing for
   Necrotizing Fasciitis
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
AB BACKGROUND: Necrotizing fasciitis is a life-threatening infection requiring urgent surgical and medical therapy. Hemodynamic stabilization and antimicrobial therapy precede aggressive surgical excision of necrotic tissue, which should be performed as soon as possible. The rapidly spreading infection and aggressive surgical intervention create challenges for wound management. Multiple dressings are available to address the various challenges associated with management of these wounds; this article discusses negative pressure therapy and antimicrobial dressings in the management of Fournier's gangrene, a form of necrotizing fasciitis that involves tissue of the genital or perianal areas.
   CASE PRESENTATION: This article reviews the case of a 56-year-old man with fever, tachycardia, and perianal pain associated with necrotizing fasciitis. Extensive surgical debridement was done on the day of admission. After several irrigations, the wound was dressed by negative pressure wound therapy with a silver dressing that minimized hospital stay and enabled early reconstruction.
   CONCLUSION: We found that negative pressure wound therapy with a silver-based dressing promoted wound healing and provided a solid matrix for surgical reconstruction.
C1 Univ Tehran Med Sci, Hazrat Rasool Hosp, Dept Gen Surg, Tehran, Iran.
C3 Tehran University of Medical Sciences
RP Pour, SM (通讯作者)，Univ Tehran Med Sci, Hazrat Rasool Hosp, Dept Gen Surg, Niayesh Ave, Tehran, Iran.
EM samanmp@yahoo.com
RI mohammadipour, saman/AAN-5852-2021
OI mohammadipour, saman/0000-0002-9178-6701
CR BARANOSKI S, 2008, WOUND CARE ESSENTIAL, P151
   Campbell PE, 2006, J WOUND OSTOMY CONT, V33, P176, DOI 10.1097/00152192-200603000-00014
   DWYER S, SILVER IS PRECIOUS W
   Miller LG, 2005, NEW ENGL J MED, V352, P1445, DOI 10.1056/NEJMoa042683
   Park H, 2010, SURG CLIN N AM, V90, P1181, DOI 10.1016/j.suc.2010.08.001
   Thwaini A, 2006, POSTGRAD MED J, V82, P516, DOI 10.1136/pgmj.2005.042069
NR 6
TC 13
Z9 19
U1 0
U2 8
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JUL-AUG
PY 2011
VL 38
IS 4
BP 449
EP 452
DI 10.1097/WON.0b013e31821e43f1
PG 4
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 791BC
UT WOS:000292633800018
PM 21747263
DA 2026-07-24
ER

PT J
AU Upton, D
   Andrews, A
AF Upton, D.
   Andrews, A.
TI Negative pressure wound therapy: improving the patient experience Part 2
   of 3
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE negative pressure wound therapy; pain; patient experience; skin trauma;
   stress; wound treatment
ID PAIN; DISTRESS; STRESS
AB Despite the clear benefits of negative pressure wound therapy (NPWT) as a treatment for wounds, it is essential that greater focus is given to the patient experience of this treatment. In particular, it is important that any unpleasant consequences, such as pain, stress, and skin trauma are minimised, so as to promote quality of life and healing. This article presents part two of three studies which aim to explore ways in which the patient experience of NPWT can be improved. In this study, the views of wound care clinicians (n=12) were investigated in greater depth through semi-structured interviews. Findings indicate a pressing need to minimise pain, particularly through ongoing assessment and collaboration with patients, and also through the use of appropriate dressings, films and other products that promote patient comfort. Additionally, it is evident that greater education is needed for both nurses and patients about NPWT, in order to promote high-quality care and patient wellbeing.
C1 [Upton, D.; Andrews, A.] Univ Worcester, Inst Hlth & Soc, Worcester, England.
C3 University of Worcester
RP Upton, D (通讯作者)，Univ Worcester, Inst Hlth & Soc, Worcester, England.
EM d.upton@worc.ac.uk
FU Molnlycke Health Care
FX This study was supported by a financial grant from Molnlycke Health
   Care. The authors have no commercial or social conflicts of interest
   with respect to the article or its content.
CR Apostoli Alberto, 2008, Prof Inferm, V61, P158
   Briggs Shiu-Ling, 2005, Prof Nurse, V20, P39
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NR 23
TC 7
Z9 9
U1 0
U2 7
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD NOV
PY 2013
VL 22
IS 11
BP 582
EP +
DI 10.12968/jowc.2013.22.11.582
PG 9
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 253PV
UT WOS:000327102700003
PM 24225598
DA 2026-07-24
ER

PT J
AU Upton, D
   Andrews, A
AF Upton, D.
   Andrews, A.
TI Negative pressure wound therapy: improving the patient experience Part 1
   of 3
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE negative pressure wound therapy; pain; patient experience; skin trauma;
   stress; wound treatment
ID DIABETIC FOOT ULCERS; PAIN; STRESS; IMPACT; CARE
AB Negative pressure wound therapy (NPWT) is an effective treatment for healing wounds, which may have additional benefits, such as reduced time spent in hospital and fewer dressing changes. However, as with most wound treatments, NPWT can be painful for some patients. Research has shown that the pain and accompanying stress of wound care can impair patient quality of life and delay the healing process, highlighting the need to explore ways in which the patient experience of NPWT might be improved. This article presents part one of three studies which aimed to investigate the above. In the present study, an online survey was used to explore the views of wound care clinicians worldwide (n = 221) on NPWT and levels of pain, stress and skin trauma in patients during the different stages of treatment. Findings suggest that, in the opinion of clinicians, patients' pain levels vary during the different stages of NPWT and that removal of the wound fillers and dressings or covering films are the most painful stages.
C1 [Upton, D.; Andrews, A.] Univ Worcester, Inst Hlth & Soc, Worcester, MA USA.
RP Upton, D (通讯作者)，Univ Worcester, Inst Hlth & Soc, Worcester, MA USA.
EM d.upton@worc.ac.uk
OI Upton, Dominic/0000-0002-5547-6204
FU Molnlycke Health Care
FX This study was supported by a financial grant from Molnlycke Health
   Care. The authors have no commercial or social conflicts of interest
   with respect to the article or its content.
CR Abbotts Joanne, 2010, Br J Nurs, V19, pS37
   Apostoli Alberto, 2008, Prof Inferm, V61, P158
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NR 34
TC 6
Z9 9
U1 0
U2 15
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD OCT
PY 2013
VL 22
IS 10
BP 552
EP 557
DI 10.12968/jowc.2013.22.10.552
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 228JS
UT WOS:000325182900005
PM 24142077
DA 2026-07-24
ER

PT J
AU Oshima, J
   Kamma, T
   Inoue, Y
   Shibuya, Y
   Sasaki, K
   Sekido, M
AF Oshima, Junya
   Kamma, Taiki
   Inoue, Yoshiaki
   Shibuya, Yoichiro
   Sasaki, Kaoru
   Sekido, Mitsuru
TI Hydrocolloid Wound Dressing for Sealing Periwound With Poor Normal Skin:
   Negative Pressure Wound Therapy for Deep Limb Burns With Extensive Burns
SO WOUND MANAGEMENT & PREVENTION
LA English
DT Article
DE burn; hydrocolloid wound dressing; negative pressure wound therapy
AB BACKGROUND: Negative pressure wound therapy (NPWT) is effective for wounds with exposed bones and tendons, but when the wound is accompanied by extensive burns, sealing is difficult. The authors performed sealing with a hydrocolloid wound dressing on limb burns. CASE REPORT: A 61-year-old woman was burned in a fire at her home. Split-thickness skin grafting was performed 14- and 35-days post-injury, but exposure of the right patella and patellar tendon became apparent. The hydrocolloid wound dressing was wrapped around the proximal and distal aspects of a deep wound. The limb was sandwiched from the front and back surfaces and sealed with 2 film dressings, including the hydrocolloid, according to the sandwich method. Using this method, NPWT could be performed without leakage, the exposed tendons and bones were covered with granulation, and skin grafts were performed on day 88 after injury. CONCLUSION: This method allows NPWT to be easily and effectively performed for deep limb burns with poor normal skin periwound area.
C1 [Oshima, Junya; Kamma, Taiki; Shibuya, Yoichiro; Sasaki, Kaoru; Sekido, Mitsuru] Univ Tsukuba, Dept Plast Reconstruct & Hand Surg, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058577, Japan.
   [Inoue, Yoshiaki] Univ Tsukuba, Dept Emergency & Crit Care Med, Tsukuba, Ibaraki, Japan.
C3 University of Tsukuba; University of Tsukuba
RP Oshima, J (通讯作者)，Univ Tsukuba, Dept Plast Reconstruct & Hand Surg, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058577, Japan.
EM ooshima-tuk@umin.ac.jp
CR Kantak NA, 2017, CLIN PLAST SURG, V44, P671, DOI 10.1016/j.cps.2017.02.023
   Niimi Y, 2021, JPRAS OPEN, V30, P156, DOI 10.1016/j.jpra.2018.08.001
   Oshima J, 2022, J BURN CARE RES, V43, P479, DOI 10.1093/jbcr/irab228
   Sahin I, 2012, Ann Burns Fire Disasters, V25, P92
NR 4
TC 0
Z9 0
U1 0
U2 5
PU HMP
PI MALVERN
PA 70 E SWEDESFORD RD, STE 100, MALVERN, PA 19355 USA
SN 2640-5237
EI 2640-5245
J9 WOUND MANAG PREV
JI Wound Manag. Prev.
PD SEP
PY 2023
VL 69
IS 3
BP 25
EP +
DI 10.25270/wmp.22095
PG 4
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA WG0L5
UT WOS:001253597800003
PM 38052012
DA 2026-07-24
ER

PT J
AU Ch'ng, JK
   Yap, CJQ
   Mo, MJ
   Chew, KY
   Png, W
   Feng, JJ
AF Ch'ng, Jack Kian
   Yap, Charyl Jia Qi
   Mo, Michelle Jiaqi
   Chew, Khong Yik
   Png, Wenxian
   Feng, Jiajun
TI Diabetic Ray Amputation Wounds Managed With Local Flap Surgery and
   Negative Pressure Wound Therapy: A Case Series
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE amputation; case series; diabetic; foot ulcer; negative-pressure wound
   therapy; surgical
ID FOOT ULCERS
AB A new surgical technique for ray amputation of the diabetic foot is described. The procedure provides soft tissue reconstruction using a local flap in combination with negative pressure wound therapy to close these wounds safely and effectively. This article reports on 12 patients treated with this technique in a Tertiary Hospital/General Hospital in Singapore and compares their outcomes to those of 12 comparative cases from neighbouring institutions under the same health group who received conventional dressings. The new technique led to a higher number of healed wounds (12 vs. 4) and a shorter median time to healing (46.5 vs. 196.5 days). No major amputation or further minor amputation of the target limb occurred in the group treated with the new technique, whereas one major amputation and two further minor amputations took place in the comparison group. Our results suggest that the new technique is promising in this diabetic population with concurrent comorbidities.
C1 [Ch'ng, Jack Kian] Sengkang Gen Hosp, Vasc Surg Serv, Singapore, Singapore.
   [Ch'ng, Jack Kian; Yap, Charyl Jia Qi] Singapore Gen Hosp, Dept Vasc Surg, Singapore, Singapore.
   [Mo, Michelle Jiaqi] Sengkang Gen Hosp, Dept Populat Hlth & Integrated Care, Singapore, Singapore.
   [Chew, Khong Yik; Feng, Jiajun] Sengkang Gen Hosp, Dept Plast Reconstruct & Aesthet Surg, Singapore, Singapore.
   [Png, Wenxian] Sengkang Gen Hosp, Dept Orthopaed Surg, Singapore, Singapore.
C3 Singapore General Hospital
RP Feng, JJ (通讯作者)，Sengkang Gen Hosp, Dept Plast Reconstruct & Aesthet Surg, Singapore, Singapore.
EM fengjj@gmail.com
RI ; FENG, Jiajun/JFJ-1528-2023
OI Yap, Charyl Jia Qi/0000-0002-8606-0842; Feng,
   Jiajun/0000-0002-6988-4145; Mo, Michelle/0009-0006-6130-5440; 
CR Armstrong David G, 2007, Int Wound J, V4, P79, DOI 10.1111/j.1742-481X.2006.00270.x
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   Thng CB, 2024, J WOUND CARE, V33, P926, DOI 10.12968/jowc.2023.0008
NR 30
TC 0
Z9 1
U1 1
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JAN 11
PY 2026
VL 23
IS 1
AR e70819
DI 10.1111/iwj.70819
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA AX6EN
UT WOS:001659179300001
PM 41520662
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Zhao, JC
   Xian, CJ
   Yu, JA
   Shi, K
AF Zhao Jing-Chun
   Xian Chun-Jing
   Yu Jia-Ao
   Shi Kai
TI Reconstruction of infected and denuded scrotum and penis by combined
   application of negative pressure wound therapy and split-thickness skin
   grafting
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Genital defects; Negative pressure wound therapy; Reconstruction;
   Split-thickness skin graft
ID GANGRENE
AB Trauma to the genital region and perineum can leave behind lifelong sequelae and pose significant challenges to surgeons in the restoration of functional ability and aesthetic status. Effective methods and techniques are indispensable during the treatment period. Negative pressure wound therapy (NPWT) is a widely accepted technique that is becoming a commonplace treatment in many clinical settings. The purpose of this case report was to introduce the efficacy of the concurrent usage of NPWT and split-thickness skin grafting (STSG) in the reconstruction of genital injuries. A man suffered a traffic accident that caused necrosis of the scrotum and penis associated with a severe infection caused by Pseudomonas aeruginosa and Enterobacter cloacea. After debridement, we adopted NPWT during the postoperative dressing changes and the application of meshed STSG. The outcomes showed that combination of NPWT and split-thickness skin grafts is safe, well-tolerated and efficient in the reconstruction of penoscrotal defects. This could be a versatile tool for reconstruction after perineal and penoscrotal trauma.
C1 [Zhao Jing-Chun; Xian Chun-Jing; Yu Jia-Ao; Shi Kai] Jilin Univ, Hosp 1, Burns & Plast Reconstruct Unit, Changchun 130031, Jilin Province, Peoples R China.
C3 Jilin University
RP Yu, JA (通讯作者)，Jilin Univ, Hosp 1, Burns & Plast Reconstruct Unit, 3302 Jilin Rd, Changchun 130031, Jilin Province, Peoples R China.
EM bu_dong007@163.com
CR Aydin T, 2010, J PLAST RECONSTR AES, V63, P1394, DOI 10.1016/j.bjps.2010.01.006
   Borgquist O, 2011, OSTOMY WOUND MANAG, V57, P44
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   Kieser DC, 2011, J WOUND CARE, V20, P35, DOI 10.12968/jowc.2011.20.1.35
   Maguiña P, 2003, BURNS, V29, P857, DOI 10.1016/j.burns.2003.07.001
   Maguina P, 2010, PLAST RECONSTR SURG, V125, p28E, DOI 10.1097/PRS.0b013e3181c2a292
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   Wang DL, 2003, BRIT J PLAST SURG, V56, P484, DOI 10.1016/S0007-1226(03)00187-5
NR 14
TC 16
Z9 16
U1 0
U2 9
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
J9 INT WOUND J
JI Int. Wound J.
PD AUG
PY 2013
VL 10
IS 4
BP 407
EP 410
DI 10.1111/j.1742-481X.2012.00997.x
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 187YM
UT WOS:000322157600010
PM 22672131
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Tian, YL
   Li, K
   Zeng, L
AF Tian, Yali
   Li, Ka
   Zeng, Ling
TI A systematic review with meta-analysis on prophylactic negative pressure
   wound therapy versus standard dressing for obese women after caesarean
   section
SO NURSING OPEN
LA English
DT Review
DE caesarean section; meta-analysis; negative-pressure wound therapy;
   nursing care; obesity; randomized controlled trial
ID SURGICAL-SITE INFECTION; PREPREGNANCY OBESITY; MATERNAL AGE; DELIVERY;
   COST; RISK; COMPLICATIONS; PREGNANCY; INCISION; OUTCOMES
AB AimsThe purpose of this study is to assess the efficacy of prophylactic negative pressure wound therapy (NPWT) in obese women undergoing caesarean section. DesignAn updated review and meta-analysis of randomized controlled trials following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. MethodsPubMed, Embase, Medline, Web of Science, and Cochrane Library were searched from inception up to March 2022 without restriction in language. We chose surgical site infection as the primary outcome. ResultsNPWT resulted in a lower surgical site infection rate compared with conventional dressing (risk ratio [RR] = 0.76). The infection rate after low transverse incision was lower comparing the NPWT group with the control group ([RR] = 0.76). No statistically significant difference was detected in blistering([RR] = 2.91). The trial sequential analysis did not support the 20% relative decrease in surgical site infection in the NPWT group. (type II error of 20%).
C1 [Tian, Yali; Li, Ka] Sichuan Univ, West China Hosp, West China Sch Nursing, Chengdu, Peoples R China.
   [Zeng, Ling] Sichuan Univ, West China Hosp, West China Sch Nursing, Dept Crit Care Med, Chengdu, Peoples R China.
   [Li, Ka; Zeng, Ling] Sichuan Univ, 37 Guoxue Alley, Chengdu, Sichuan, Peoples R China.
C3 Sichuan University; Sichuan University; Sichuan University
RP Li, K; Zeng, L (通讯作者)，Sichuan Univ, 37 Guoxue Alley, Chengdu, Sichuan, Peoples R China.
EM lika127@126.com; zengling510@163.com
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NR 75
TC 5
Z9 7
U1 1
U2 10
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN, NJ 07030 USA
SN 2054-1058
J9 NURS OPEN
JI NURS. OPEN
PD SEP
PY 2023
VL 10
IS 9
BP 5999
EP 6013
DI 10.1002/nop2.1912
EA JUN 2023
PG 15
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA W7DY2
UT WOS:001013370400001
PM 37365685
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kashimura, T
   Yoshida, K
   Soejima, K
AF Kashimura, Tsutomu
   Yoshida, Kotoku
   Soejima, Kazutaka
TI A Novel Technique of Negative Pressure Wound Therapy for Pharyngeal
   Cutaneous Fistulas Around Tracheostomas
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Esophago-jejunal anastomosis; free jejunal transplantation; negative
   pressure wound therapy; pharyngeal cutaneous fistula; tracheostoma
ID CLOSURE
AB Fistula formation after free jejunal transplantation is relatively common; however, treating esophago-jejunal anastomosis fistulas is difficult. Herein, the authors report a case of esophago-jejunal anastomosis fistula adjacent to the permanent tracheostoma after free jejunal transplantation that was closed using negative pressure wound therapy (NPWT). A 70-year-old man underwent total pharyngo-laryngo-cervical esophagectomy and free jejunal transplantation for hypopharyngeal cancer. After reconstruction, an esophago-jejunal anastomosis fistula developed on the permanent tracheostoma margin. The fistula was sutured, but it recurred. Therefore, NPWT was performed to close the fistula via the bridge method and balloon compression using a tracheal cannula. NPWT requires the maintenance of local negative pressure. However, esophago-jejunal anastomosis fistula formation after free jejunal transplantation makes this difficult because of the unevenness of the permanent tracheostoma and moist surface of the tracheal mucosa. NPWT performed using the bridge method and balloon compression is an effective option for fistula treatment.
C1 [Kashimura, Tsutomu; Yoshida, Kotoku; Soejima, Kazutaka] Nihon Univ, Sch Med, Dept Plast & Reconstruct Surg, Tokyo, Japan.
C3 Nihon University
RP Kashimura, T (通讯作者)，Nihon Univ, Sch Med, Dept Plast & Reconstruct Surg, Itabashi Ku, 30-1 Ooyaguchikami Cho, Tokyo 1738610, Japan.
EM kashimura.tsutomu@nihon-u.ac.jp
CR Aksakal IA, 2014, J HAND SURG-AM, V39, P1022, DOI 10.1016/j.jhsa.2014.02.016
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   Mir A, 2019, LARYNGOSCOPE, V129, P671, DOI 10.1002/lary.27262
NR 8
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD NOV-DEC
PY 2021
VL 32
IS 8
BP E765
EP E767
DI 10.1097/SCS.0000000000007763
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WP8DF
UT WOS:000713355900046
PM 34224456
DA 2026-07-24
ER

PT J
AU Takai, K
   Saeki, M
   Takaoka, S
   Tada, Y
   Fujimura, R
   Harada, T
   Yamauchi, T
   Kumano, H
AF Takai, Kanako
   Saeki, Maki
   Takaoka, Seiji
   Tada, Yusuke
   Fujimura, Ryuta
   Harada, Tamaki
   Yamauchi, Takashi
   Kumano, Hodaka
TI Negative pressure wound therapy for prolonged surgical wound healing
   after brachiobasilic arteriovenous fistula creation in a patient with
   end-stage liver failure
SO JOURNAL OF VASCULAR ACCESS
LA English
DT Editorial Material
DE Hemodialysis vascular access; arteriovenous fistula creation; excessive
   exudative discharge; negative pressure wound therapy; brachiobasilic
   arteriovenous fistula
ID MALNUTRITION; DISEASE
AB A 54-year-old male patient diagnosed with hepatorenal syndrome caused by decompensated alcoholic cirrhosis was referred for arteriovenous fistula (AVF) creation after initiation of hemodialysis. A brachiobasilic arteriovenous fistula (BBAVF) was created because neither forearm had suitable vasculature. Large-volume serous effusion from the incision persisted postoperatively, and we started negative pressure wound therapy (NPWT) for wound protection. The effusion volume decreased gradually; however, up to 80 ml of discharge continued daily. Re-operation was performed 35 days after the initial operation, followed by continued NPWT. The wound was almost healed 85 days after the primary surgery. We present a case of severe surgical wound complication after AVF creation in a patient with hemostatic and coagulation disorders and malnutrition caused by end-stage hepatic failure. We confirmed the usefulness of NPWT for excessive surgical wound effusion and the adequacy of BBAVF for vascular access.
C1 [Takai, Kanako; Tada, Yusuke; Kumano, Hodaka] Higashiosaka City Med Ctr, Dept Crit Care Med, 3-4-5 Nishiiwata, Higashiosaka, Osaka 5788588, Japan.
   [Saeki, Maki] Higashiosaka City Med Ctr, Nursing Dept, Higashiosaka, Osaka, Japan.
   [Takaoka, Seiji; Fujimura, Ryuta; Harada, Tamaki] Higashiosaka City Med Ctr, Dept Nephrol, Higashiosaka, Osaka, Japan.
   [Yamauchi, Takashi] Higashiosaka City Med Ctr, Dept Cardiovasc Surg, Higashiosaka, Osaka, Japan.
RP Takai, K (通讯作者)，Higashiosaka City Med Ctr, Dept Crit Care Med, 3-4-5 Nishiiwata, Higashiosaka, Osaka 5788588, Japan.
EM takai-k@higashiosaka-hosp.jp
OI Takai, Kanako/0000-0001-9107-3691
CR Artigas A, 2016, J CRIT CARE, V33, P62, DOI 10.1016/j.jcrc.2015.12.019
   Berbel-Franco D, 2020, J CARDIOTHORAC SURG, V15, DOI 10.1186/s13019-020-01133-y
   Chan KS, 2020, INT WOUND J, V17, P1231, DOI 10.1111/iwj.13376
   Cheung K, 2012, CLIN GASTROENTEROL H, V10, P117, DOI 10.1016/j.cgh.2011.08.016
   COBURN MC, 1994, J VASC SURG, V20, P896, DOI 10.1016/0741-5214(94)90226-7
   Ho JWC, 2015, CLIN NUTR, V34, P679, DOI 10.1016/j.clnu.2014.07.012
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Traub J, 2021, NUTRIENTS, V13, DOI 10.3390/nu13020540
   Wetterkamp M, 2020, BIOLOGY-BASEL, V9, DOI 10.3390/biology9110349
NR 10
TC 0
Z9 0
U1 0
U2 1
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1129-7298
EI 1724-6032
J9 J VASC ACCESS
JI J. Vasc. Access
PD JAN
PY 2024
VL 25
IS 1
BP 327
EP 330
AR 11297298221106102
DI 10.1177/11297298221106102
EA JUN 2022
PG 4
WC Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA HG2C3
UT WOS:000812284800001
PM 35708249
DA 2026-07-24
ER

PT J
AU Jang, MY
   Hong, JP
   Bordianu, A
   Suh, HS
AF Jang, Min Young
   Hong, Joon Pio
   Bordianu, Anca
   Suh, Hyun Suk
TI Using a Contradictory Approach to Treat a Wound Induced by Hematoma in a
   Patient With Antiphospholipid Antibody Syndrome Using Negative Pressure
   Wound Therapy: Lessons Learnt
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE negative pressure wound therapy (NPWT); wound; antiphospholipid antibody
   syndrome; hematoma; bleeding
ID MANAGEMENT; EFFICACY
AB A 48-year-old woman with antiphospholipid syndrome (APS) had multiple skin necrosis caused by massive bleeding and hematoma collection at the right lower leg, left thigh, and abdomen. During the first month, we did surgical debridement every 2 to 3 days with meticulous coagulation and applied negative pressure wound therapy (NPWT). Then as the base showed initial granulation, we changed the NPWT every 4 days. NPWT was used with lower pressure and cyclic mode (-40 to -75 mm Hg) to minimize trauma and to reduce the possibility of bleeding from the wounds. After 2 months of NPWT treatment, all the wounds eventually healed with secondary intension despite the patient's condition with diabetes, hemodialysis, anticoagulant use, and corticosteroid therapy. This report supports the idea that if accompanied by conservative debridement with meticulous bleeding control, application of NPWT in low pressures and close monitoring of the patient, NPWT is possible to use even in wounds of patients with risk for bleeding.
C1 [Jang, Min Young; Hong, Joon Pio; Suh, Hyun Suk] Univ Ulsan, Seoul Asan Med Ctr, Coll Med, Seoul, South Korea.
   [Bordianu, Anca] Carol Davila Univ Med & Pharm, Bucharest, Romania.
C3 University of Ulsan; Asan Medical Center; Carol Davila University of
   Medicine & Pharmacy
RP Suh, HS (通讯作者)，Asan Med Ctr, Dept Plast Surg, Poongnap2 Dong,388-1, Seoul 138736, South Korea.
EM hyunsuk.suh@amc.seoul.kr
RI SUH, Hyunsuk/ABE-9911-2020; Hong, Joon/AEV-0712-2022; /AAS-5572-2020
CR [Anonymous], 2014, CADTH Rapid Response Reports
   Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   Bovill E, 2008, INT WOUND J, V5, P511, DOI 10.1111/j.1742-481X.2008.00437.x
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Kim EK, 2007, ANN PLAS SURG, V58, P536, DOI 10.1097/01.sap.0000245121.32831.47
   Lee KN, 2015, INT WOUND J, V12, P686, DOI 10.1111/iwj.12201
   Pasquali JL, 2008, BEST PRACT RES CL RH, V22, P831, DOI 10.1016/j.berh.2008.08.008
   Pazzola G, 2015, CURR RHEUMATOL REP, V17, DOI 10.1007/s11926-014-0481-0
NR 9
TC 8
Z9 10
U1 1
U2 10
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD SEP
PY 2015
VL 14
IS 3
SI SI
BP 303
EP 306
DI 10.1177/1534734615598421
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CT3MN
UT WOS:000362710900016
PM 26248826
DA 2026-07-24
ER

PT J
AU Lin, FY
   Kempny, T
   Knoz, M
   Cheng, HT
AF Lin, Fu-Yu
   Kempny, Tomas
   Knoz, Martin
   Cheng, Hsu-Tang
TI Meta-analysis of randomized controlled studies of closed incisional
   negative pressure wound therapy versus standard wound dressing in the
   prevention of surgical site infections for patients undergoing surgeries
   for lower extremity fractures
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Letter
C1 [Lin, Fu-Yu] China Med Univ, China Med Univ Hosp, Sch Med, Dept Neurol, Taichung, Taiwan.
   [Kempny, Tomas; Knoz, Martin] Masaryk Univ, Univ Hosp Brno, Fac Med, Dept Burns & Plast Surg, Jihlavska 20, Brno 62500, Czech Republic.
   [Kempny, Tomas] MEDICent Clin, Ctvrti 22, Ostrava 70300, Czech Republic.
   [Kempny, Tomas] Univ Ostrava, Inst Emergency Med, Fac Med, Syllabova 19, Ostrava 70300, Czech Republic.
   [Knoz, Martin] St Annes Univ Hosp, Fac Med, Clin Plast & Aesthet Surg, Pekarska 664-53, Brno 60200, Czech Republic.
   [Cheng, Hsu-Tang] Asia Univ, Asia Univ Hosp, Coll Med & Hlth Sci, Div Plast & Reconstruct Surg,Dept Surg, Taichung, Taiwan.
   [Cheng, Hsu-Tang] Asia Univ, Dept Food Nutr & Hlth Biotechnol, Taichung, Taiwan.
   [Cheng, Hsu-Tang] China Med Univ Hosp, Big Data Ctr, Taichung, Taiwan.
   [Cheng, Hsu-Tang] 222 Fuxin Rd, Taichung 41354, Taiwan.
C3 China Medical University Taiwan; China Medical University Hospital -
   Taiwan; University Hospital Brno; University Hospital Vinohrady; Masaryk
   University; University of Ostrava; St. Anne's University Hospital Brno
   (FNUSA); Masaryk University; Asia University Taiwan; Asia University
   Taiwan; China Medical University Taiwan; China Medical University
   Hospital - Taiwan
RP Cheng, HT (通讯作者)，Asia Univ, Asia Univ Hosp, Coll Med & Hlth Sci, Div Plast & Reconstruct Surg,Dept Surg, Taichung, Taiwan.
EM hsutangcheng@gmail.com
RI Knoz, Martin/IUM-3364-2023
FU China Medical University Hospital Research Grant [DMR-112083]; Asia
   University Hospital Research Program [AUH-11151009]; European Union
   [CZ.02.1.01/0.0/0.0/17_049/0008441]; state budget of the Czech Republic
FX China Medical University Hospital Research Grant DMR-112-083.Asia
   University Hospital Research Program, Grant Number: AUH-11151009This
   paper was supported by project No. CZ.02.1.01/0.0/0.0/17_049/0008441
   "Innovative Therapeutic Methods of Musculoskeletal System in Accident
   Surgery" within the Operational Programme Research, Development and
   Education financed by the European Union and by the state budget of the
   Czech Republic.
NR 0
TC 0
Z9 0
U1 1
U2 6
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD APR
PY 2023
VL 79
BP 68
EP 73
DI 10.1016/j.bjps.2023.01.034
EA MAR 2023
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA H4GN1
UT WOS:000995566300001
PM 36870102
DA 2026-07-24
ER

PT J
AU Schecter, WP
   Hirshberg, A
   Chang, DS
   Harris, HW
   Napolitano, LM
   Wexner, SD
   Dudrick, SJ
AF Schecter, William P.
   Hirshberg, Asher
   Chang, David S.
   Harris, Hobart W.
   Napolitano, Lena M.
   Wexner, Steven D.
   Dudrick, Stanley J.
TI Enteric Fistulas: Principles of Management
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Article; Proceedings Paper
CT 94th Annual Clinical Congress of the American-College-of-Surgeons (ACS)
   / 63rd Annual Sessions of the Owen H Wangensteen Forum on Fundamental
   Surgical Problems
CY OCT 12-16, 2008
CL San Francisco, CA
SP Amer Coll Surg (ACS)
ID POSTOPERATIVE ENTEROCUTANEOUS FISTULAS; VACUUM-ASSISTED CLOSURE;
   ABDOMINAL-WALL DEFECTS; ACELLULAR DERMAL MATRIX; CRITICALLY-ILL
   PATIENTS; HUMAN GROWTH-HORMONE; GASTROINTESTINAL FISTULAS; OPEN ABDOMEN;
   RANDOMIZED-TRIAL; CROHNS-DISEASE
C1 [Schecter, William P.; Hirshberg, Asher; Chang, David S.; Harris, Hobart W.; Napolitano, Lena M.; Wexner, Steven D.; Dudrick, Stanley J.] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Surg, San Francisco, CA 94110 USA.
C3 University of California System; University of California San Francisco
RP Schecter, WP (通讯作者)，Univ Calif San Francisco, San Francisco Gen Hosp, Dept Surg, 1001 Potrero Ave, San Francisco, CA 94110 USA.
RI Wexner, Steven D/AFG-8251-2022; Napolitano, Lena/AAZ-8651-2021
OI Wexner, Steven D/0000-0001-8046-5753; 
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NR 84
TC 143
Z9 170
U1 0
U2 12
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD OCT
PY 2009
VL 209
IS 4
BP 484
EP 491
DI 10.1016/j.jamcollsurg.2009.05.025
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 506CD
UT WOS:000270749900009
PM 19801322
DA 2026-07-24
ER

PT J
AU Dueñas, V
   Kindt, P
AF Duenas, Violeta
   Kindt, Philipp
TI Flank fold flap after tumor resection on the right thigh of a dog
SO KLEINTIERPRAXIS
LA German
DT Article
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; ADVANCEMENT FLAPS;
   SURGICAL EXCISION; PATTERN FLAPS; SKIN FLAPS; TISSUE; PRINCIPLES;
   MANAGEMENT; PERFUSION
C1 [Duenas, Violeta] AniCura Kleintierzentrum Reutlingen, August Lammle Str 51, D-72766 Reutlingen, Germany.
   [Kindt, Philipp] Kleintierklin Ludwigsburg Ossweil Part AniCura, Ludwigsburg, Germany.
RP Dueñas, V (通讯作者)，AniCura Kleintierzentrum Reutlingen, August Lammle Str 51, D-72766 Reutlingen, Germany.
EM violeta.duenas@anicura.de
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NR 30
TC 0
Z9 0
U1 0
U2 1
PU M H SCHAPER GMBH CO KG
PI ALFELD
PA BORSIGSTRASSE 5, POSTFACH 16 42, 310460 ALFELD, GERMANY
SN 0023-2076
J9 KLEINTIERPRAXIS
JI Kleintierpraxis
PD FEB
PY 2024
VL 69
IS 2
DI 10.2377/0023-2076-69-58
PG 52
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA HZ4F0
UT WOS:001163313800002
DA 2026-07-24
ER

PT J
AU Png, ME
   Madan, JJ
   Dritsaki, M
   Achten, J
   Parsons, N
   Fernandez, M
   Grant, R
   Nanchahal, J
   Costa, ML
AF Png, May Ee
   Madan, Jason J.
   Dritsaki, Melina
   Achten, Juul
   Parsons, Nick
   Fernandez, Miguel
   Grant, Richard
   Nanchahal, Jagdeep
   Costa, Matthew L.
CA WHiST Trial Collaborators
TI Cost-utility analysis of standard dressing compared with incisional
   negative-pressure wound therapy among patients with closed surgical
   wounds following major trauma to the lower limb (vol 102-B, pg 1072,
   2020)
SO BONE & JOINT JOURNAL
LA English
DT Correction
RI Achten, Juul/KUD-8515-2024
CR Png ME, 2020, BONE JOINT J, V102B, P1072, DOI 10.1302/0301-620X.102B8.BJJ-2020-0126.R1
NR 1
TC 0
Z9 0
U1 0
U2 0
PU BRITISH EDITORIAL SOC BONE & JOINT SURGERY
PI LONDON
PA 22 BUCKINGHAM STREET, LONDON WC2N 6ET, ENGLAND
SN 2049-4394
J9 BONE JOINT J
JI Bone Joint J.
PD OCT
PY 2022
VL 104B
IS 10
BP 1190
EP 1190
PG 1
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA H2EZ0
UT WOS:000994161000014
DA 2026-07-24
ER

PT J
AU Eo, S
   Kim, Y
   Cho, S
AF Eo, SuRak
   Kim, YoongSoo
   Cho, SangHun
TI Vacuum-assisted closure improves the incorporation of artificial dermis
   in soft tissue defects: Terudermis® and Pelnac®
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Artificial dermal substitutes; Pelnac (R); Terudermis (R);
   Vacuum-assisted closure
ID SECURING SKIN-GRAFTS; NEGATIVE-PRESSURE DRESSINGS; CLINICAL-TRIAL;
   PENILE SHAFT; RECONSTRUCTION; THERAPY; BOLSTER; INTEGRA; DEVICE
AB As a dermal scaffold, artificial dermal substitutes allow the body to accomplish its own tissue regeneration through infiltration of cells and neovascularisation. However, they show not only rather lower take rates compared to autologous skin grafts alone, but they also require more time for sufficient vascular ingrowth to overlay the skin graft. To accelerate this overlaying, we applied vacuum-assisted closure negative-pressure settings over the artificial dermis: Terudermis (R) and Pelnac (R) grafts. Fourteen patients with complex tissue defects were treated, including bone exposure in two cases, tendon exposure in seven cases and soft tissue defects in five cases. Nine cases had combined wound infections. The time interval between the first artificial dermis graft and the second split-thickness skin graft over it was 7 center dot 64 days on average. Dermal substitutes took place completely in all cases and there were no graft failures.
C1 [Eo, SuRak; Cho, SangHun] DongGuk Univ Int Hosp, Dept Plast & Reconstruct Surg, Ilsan, South Korea.
   [Kim, YoongSoo] Kims Plast Surg Clin, Seoul, South Korea.
C3 Dongguk University
RP Eo, S (通讯作者)，DongGuk Univ Int Hosp, Dept Plast & Reconstruct Surg, 814 SikSa Dong, Goyang Si 410773, Gyeonggi Do, South Korea.
EM surakeo@yahoo.com
RI Eo, SuRak/JXM-4124-2024
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NR 39
TC 57
Z9 66
U1 0
U2 13
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2011
VL 8
IS 3
BP 261
EP 267
DI 10.1111/j.1742-481X.2011.00780.x
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 762OI
UT WOS:000290488900009
PM 21561535
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Vikatmaa, P
   Juutilainen, V
AF Vikatmaa, P.
   Juutilainen, V.
TI Comment on: "Negative Pressure Wound Therapy: a Systematic Review of
   Effectiveness and Safety", P. Vikatmaa, V. Juutilainen, P. Kuukasjarvi,
   A. Malmivaara, Eur J Vasc Endovasc Surg 2008;36(4):438-48
   Response
SO EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
LA English
DT Letter
C1 [Vikatmaa, P.] Univ Helsinki, Cent Hosp, Dept Surg, Div Vasc Surg, Helsinki 00029, HUS, Finland.
   [Juutilainen, V.] Univ Helsinki, Cent Hosp, Dept Surg, Div Plast & Reconstruct Surg, Helsinki 00029, HUS, Finland.
C3 University of Helsinki; Helsinki University Central Hospital; Hyvinkaan
   Sairaala; University of Helsinki; Helsinki University Central Hospital;
   Hyvinkaan Sairaala
RP Vikatmaa, P (通讯作者)，Univ Helsinki, Cent Hosp, Dept Surg, Div Vasc Surg, PB 340, Helsinki 00029, HUS, Finland.
EM pirkka.vikatmaa@hus.fi
CR *INT COMM MED J ED, 2008, BIOMED J OCT UNPUB
NR 1
TC 0
Z9 0
U1 0
U2 3
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 1078-5884
J9 EUR J VASC ENDOVASC
JI Eur. J. Vasc. Endovasc. Surg.
PD JUN
PY 2009
VL 37
IS 6
BP 741
EP 742
DI 10.1016/j.ejvs.2009.01.024
PG 2
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA 465LC
UT WOS:000267585100020
DA 2026-07-24
ER

PT J
AU Atema, JJ
   van Buijtenen, JM
   Lamme, B
   Boermeester, MA
AF Atema, Jasper J.
   van Buijtenen, Jesse M.
   Lamme, Bas
   Boermeester, Marja A.
TI Clinical studies on intra-abdominal hypertension and abdominal
   compartment syndrome
SO JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
LA English
DT Review
ID SEVERE ACUTE-PANCREATITIS; CRITICALLY-ILL PATIENTS; VACUUM-ASSISTED
   CLOSURE; MULTIPLE ORGAN FAILURE; LAPAROSCOPIC CHOLECYSTECTOMY;
   INTERNATIONAL-CONFERENCE; ANEURYSM REPAIR; BURNED PATIENTS; PRESSURE;
   RESUSCITATION
C1 [Atema, Jasper J.; Boermeester, Marja A.] Acad Med Ctr, Dept Surg, Dordrecht, Netherlands.
   [van Buijtenen, Jesse M.] Vrije Univ Amsterdam, Med Ctr, Dept Surg, Dordrecht, Netherlands.
   [Lamme, Bas] Albert Schweitzer Hosp, Dept Surg, Dordrecht, Netherlands.
C3 Vrije Universiteit Amsterdam; Albert Schweitzer Ziekenhuis
RP Boermeester, MA (通讯作者)，Acad Med Ctr, Dept Surg G4 132 1, PB 22660, NL-10100 DD Amsterdam, Netherlands.
EM m.a.boermeester@amc.uva.nl
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NR 76
TC 9
Z9 11
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 2163-0755
EI 2163-0763
J9 J TRAUMA ACUTE CARE
JI J. Trauma Acute Care Surg.
PD JAN
PY 2014
VL 76
IS 1
BP 234
EP 240
DI 10.1097/TA.0b013e3182a85f59
PG 7
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Surgery
GA AH8JN
UT WOS:000336384200043
PM 24368386
DA 2026-07-24
ER

PT J
AU Portou, M
   Bernaerts, K
   Bassetto, F
   Cherubino, M
   Collier, M
   Hirche, C
   Horch, RE
   Mall, JW
   O'Brien, G
   Piaggesi, A
   Porter, C
   Probst, S
   Rashid, ST
   Trivedi, S
AF Portou, Mark
   Bernaerts, Kris
   Bassetto, Franco
   Cherubino, Mario
   Collier, Mark
   Hirche, Christoph
   Horch, Raymund E.
   Mall, Julian W.
   O'Brien, Gillian
   Piaggesi, Alberto
   Porter, Claire
   Probst, Sebastian
   Rashid, S. Tawqeer
   Trivedi, Sadhana
TI Negative pressure wound therapy made simple: expert panel
   recommendations
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE algorithm; negative pressure wound therapy; negative pressure wound
   therapy with instillation; NPWT; NPWTi-d; single-use NPWT system; sNPWT;
   wound; wound care; wound dressing; wound healing
ID INSTILLATION
AB Objective: Wound management poses a substantial economic burden, and the prevalence of hard-to-heal (chronic) wounds is a growing health concern. Negative pressure wound therapy (NPWT), with and without instillation, is an adjunctive therapy commonly used to manage acute and hard-to-heal wounds and has demonstrated positive clinical outcomes. The variety of NPWT modalities, patient needs, wound characteristics and care requirements can make selecting the optimal system challenging, leading to uncertainty and inconsistent practices among new users, increasing the risk of suboptimal outcomes. This article provides practical guidance to help new NPWT users make confident, evidence-based decisions. Method: An expert panel was convened in Amsterdam, the Netherlands, in November 2023 to review published treatment guidelines and the current literature and to develop simplified recommendations on the use of NPWT in hospital and community care settings. Results: Expert panel members discussed published wound management evidence and their real-world experiences as wound management specialists to generate recommendations for healthcare professionals to aid them in the selection of NPWT modalities. Conclusion: This summary presents nine expert panel recommendations, including simplified risk assessment algorithms and guidance to improve NPWT use across clinical settings. Declaration of interest: ST is an employee of Solventum. All other authors have consulting agreements with Solventum. Funding for the advisory panel meeting was provided by Solventum. The authors have no other conflicts of interest to declare.
C1 [Portou, Mark] Royal Free London NHS Fdn Trust, London, England.
   [Bernaerts, Kris] Univ Hosp Leuven, Leuven, Belgium.
   [Bassetto, Franco] Univ Padua, Clin Plast & Reconstruct Surg, Padua, Italy.
   [Cherubino, Mario] Cleveland Clin Abu Dhabi, Abu Dhabi, U Arab Emirates.
   [Collier, Mark] Tissue Viabil, Lincoln, Lincs, England.
   [Collier, Mark] Univ Lincoln, Lincoln, England.
   [Hirche, Christoph] Goethe Univ Frankfurt, BG Unfallklin Frankfurt am Main, Frankfurt, Germany.
   [Horch, Raymund E.] Univ Hosp Erlangen, Erlangen, Bavaria, Germany.
   [Mall, Julian W.] Klinikum Reg Hannover, Hannover, Germany.
   [O'Brien, Gillian] Naas Gen Hosp, Naas, Kildare, Ireland.
   [Piaggesi, Alberto] Univ Pisa, Pisa, Italy.
   [Porter, Claire] Univ Hosp Leicester, Leicester, England.
   [Probst, Sebastian] HES SO Univ Appl Sci & Arts Western Switzerland, Geneva, Switzerland.
   [Rashid, S. Tawqeer] Manchester Univ Hosp NHS Fdn Trust, Manchester, England.
   [Trivedi, Sadhana] Solventum, Med Surg, Dublin, Ireland.
C3 University of London; University College London; Royal Free London NHS
   Foundation Trust; KU Leuven; University Hospital Leuven; University of
   Padua; Cleveland Clinic Foundation; University of Lincoln; Goethe
   University Frankfurt; University of Erlangen Nuremberg; University of
   Pisa; University of Leicester; University Hospitals of Leicester NHS
   Trust; University of Applied Sciences & Arts Western Switzerland;
   Wythenshawe Hospital NHS Foundation Trust
RP Portou, M (通讯作者)，Royal Free London NHS Fdn Trust, London, England.
EM m.portou@nhs.net
RI Probst, Sebastian/AAN-6968-2020; Horch, Raymund/H-8128-2019; Cherubino,
   Mario/N-1780-2019; Rashid, T/B-9474-2008
OI Probst, Sebastian/0000-0001-9603-1570; 
FX Acknowledgements The authors would like to thank Matthew Cooper and
   Christian Seelandt (Solventum) for their participation in the expert
   panel, and to thank Maritza Quintero, Ashley Collinsworth, Julissa Ramos
   and Ricardo R Martinez (Solventum) for their assistance with manuscript
   preparation and editing.
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NR 35
TC 0
Z9 0
U1 1
U2 1
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD APR
PY 2026
VL 35
IS 4
BP 292
EP 298
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA GF4ZS
UT WOS:001735160400001
PM 41926464
DA 2026-07-24
ER

PT J
AU Steinbichler, TB
   Wolfram, D
   Runge, A
   Hartl, R
   Dejaco, D
   Rauchenwald, T
   Pototschnig, C
   Riechelmann, H
   Schartinger, VH
AF Steinbichler, Teresa Bernadette
   Wolfram, Dolores
   Runge, Annette
   Hartl, Roland
   Dejaco, Daniel
   Rauchenwald, Tina
   Pototschnig, Claus
   Riechelmann, Herbert
   Schartinger, Volker Hans
TI Modified vacuum-assisted closure (EndoVAC) therapy for treatment of
   pharyngocutaneous fistula: A case series and a review of the literature
SO HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND
   NECK
LA English
DT Review
DE head and neck cancer; laryngectomy; negative&#8208; pressure wound
   therapy; radiochemotherapy; salvage surgery
AB Background Pharyngocutaneous fistula is a potential life-threatening complication following head and neck surgery. There is only limited evidence about the efficacy of vacuum-assisted closure (VAC) therapy and endoscopic vacuum-assisted closure (EndoVAC) therapy for the treatment of pharyngocutaneous fistulas.
   Methods In this article, we report on a consecutive case series of six male patients with pharyngocutaneous fistula treated with a modified outside-in EndoVAC technique. We also present a review of the current related literature.
   Results EndoVAC therapy alone was successful in five of the six patients (83.3%) with a median duration of EndoVAC therapy of 18.5 days (range: 7 to 32 days) and a median number of EndoVAC sponge changes of 4 (range: 1 to 9 changes). One patient needed additional reconstructive surgery after prior radiochemotherapy and jejunal transfer. No treatment-related complications were observed.
   Conclusion EndoVAC therapy is an easy-to-perform, safe procedure for the treatment of pharyngocutaneous fistulae.
C1 [Steinbichler, Teresa Bernadette; Runge, Annette; Hartl, Roland; Dejaco, Daniel; Pototschnig, Claus; Riechelmann, Herbert; Schartinger, Volker Hans] Med Univ Innsbruck, Dept Otorhinolaryngol Head & Neck Surg, Anichstr 35, A-6020 Innsbruck, Austria.
   [Wolfram, Dolores; Rauchenwald, Tina] Med Univ Innsbruck, Dept Plast Reconstruct & Aesthet Surg, Innsbruck, Austria.
C3 Medical University of Innsbruck; Medical University of Innsbruck
RP Schartinger, VH (通讯作者)，Med Univ Innsbruck, Dept Otorhinolaryngol Head & Neck Surg, Anichstr 35, A-6020 Innsbruck, Austria.
EM volker.schartinger@i-med.ac.at
OI Schartinger, Volker/0000-0002-5887-7644; Wolfram,
   Dolores/0000-0003-0920-7211; Steinbichler, Teresa
   Bernadette/0000-0002-2666-226X; Runge, Annette/0000-0003-1211-3996;
   Deutinger, Tina/0000-0002-7555-1582
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   Wetzel-Roth W, 2004, ZBL CHIR, V129, pS7, DOI 10.1055/s-2004-822677
NR 31
TC 15
Z9 16
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1043-3074
EI 1097-0347
J9 HEAD NECK-J SCI SPEC
JI Head Neck-J. Sci. Spec. Head Neck
PD AUG
PY 2021
VL 43
IS 8
BP 2377
EP 2384
DI 10.1002/hed.26684
EA APR 2021
PG 8
WC Otorhinolaryngology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology; Surgery
GA TE2IF
UT WOS:000637780800001
PM 33830587
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Shilt, JS
   Yoder, JS
   Manuck, TA
   Jacks, L
   Rushing, J
   Smith, BP
AF Shilt, JS
   Yoder, JS
   Manuck, TA
   Jacks, L
   Rushing, J
   Smith, BP
TI Role of vacuum-assisted closure in the treatment of pediatric lawnmower
   injuries
SO JOURNAL OF PEDIATRIC ORTHOPAEDICS
LA English
DT Article
DE lawnmower injuries; vacuum-assisted closure; pediatric trauma; soft
   tissue defects
ID LAWN-MOWER INJURIES; LOWER-EXTREMITY; DEGLOVING INJURIES; WOUND CONTROL;
   CHILDREN; MANAGEMENT; AMPUTATION; PRESSURE; FOOT
AB Lawnmower injuries in children often present treatment challenges due to complex soft tissue damage. Vacuum-assisted closure (VAC), the application of controlled subatmospheric pressure to a wound surface, has been used to treat complex lacerations in many patients and has been shown to be safe and effective in children. However, VAC treatment of lawnmower injuries in children has not been reported. This study analyzes the outcomes of treatment following the use of VAC in children with lawnmower injuries and compares the results of VAC treatment to historical controls who were treated before VAC was available for wound treatment. The use of VAC demonstrated a trend toward a decrease in revision amputations and an improvement in function after treatment. There were no complications or adverse reactions related to VAC treatment. The VAC system is a safe and effective method of treating soft tissue injuries resulting from lawnmower accidents in children.
C1 Wake Forest Univ, Sch Med, Dept Orthopaed Surg, Winston Salem, NC USA.
   Wake Forest Univ, Sch Med, Dept Publ Hlth Sci, Winston Salem, NC USA.
C3 Wake Forest University; Wake Forest University
RP Shilt, JS (通讯作者)，Wake Forest Univ, Sch Med, Dept Orthopaed, Winston Salem, NC 27157 USA.
EM jshilt@wfubmc.edu
OI Manuck, Tracy/0000-0002-2465-6747
CR ALONSO JE, 1995, J PEDIATR ORTHOPED, V15, P83, DOI 10.1097/01241398-199501000-00018
   ANGER DM, 1995, J BONE JOINT SURG AM, V77A, P719, DOI 10.2106/00004623-199505000-00008
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NR 23
TC 30
Z9 42
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0271-6798
J9 J PEDIATR ORTHOPED
JI J. Pediatr. Orthop.
PD SEP-OCT
PY 2004
VL 24
IS 5
BP 482
EP 487
DI 10.1097/01241398-200409000-00006
PG 6
WC Orthopedics; Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Pediatrics
GA 849YA
UT WOS:000223576400006
PM 15308896
DA 2026-07-24
ER

PT J
AU Luedders, DW
   Bohlmann, MK
   Hornemann, A
   Dittmer, C
   Diedrich, K
   Thill, M
AF Luedders, Doerte W.
   Bohlmann, Michael K.
   Hornemann, Amadeus
   Dittmer, Christine
   Diedrich, Klaus
   Thill, Marc
TI Successful application of vacuum-assisted closure therapy for treatment
   of mastitis-associated chronic breast wounds
SO ARCHIVES OF GYNECOLOGY AND OBSTETRICS
LA English
DT Article
DE Breast; Mastitis; Surgery; Vacuum-assisted closure
ID TOPICAL NEGATIVE-PRESSURE; SALVAGE; RECONSTRUCTION; MANAGEMENT; DEVICE
AB Although non-puerperal mastitis is rare and its cause is rather unclear, the number of patients diagnosed with this defect is increasing. In some cases, standard therapy fails and it progresses to a chronic disease. Vacuum-assisted closure (VAC) therapy has shown good results in healing complex wounds.
   The goal of this study was to evaluate our experiences with VAC therapy and to answer the question whether or not should be accepted as an effective treatment in healing chronic wounds caused by non-puerperal mastitis. Retrospectively, we identified five patients with a non-puerperal mastitis chronic wound that was treated using VAC and report on their outcome.
   We reached both wound control and closure of the breast wounds in all patients.
   According to our findings, the VAC therapy can be considered when managing challenging breast wounds, particularly when other therapeutic options have failed. The role of VAC therapy as a primary therapeutic option has not yet been evaluated.
C1 [Luedders, Doerte W.; Bohlmann, Michael K.; Dittmer, Christine; Diedrich, Klaus; Thill, Marc] Univ Hosp Schleswig Holstein, Dept Obstet & Gynaecol, D-23538 Lubeck, Germany.
   [Hornemann, Amadeus] Univ Heidelberg, Univ Hosp Mannheim, Dept Obstet & Gynaecol, D-68167 Mannheim, Germany.
C3 University of Kiel; Schleswig Holstein University Hospital; Ruprecht
   Karls University Heidelberg
RP Luedders, DW (通讯作者)，Univ Hosp Schleswig Holstein, Dept Obstet & Gynaecol, Campus Lubeck,Ratzeburger Allee 160, D-23538 Lubeck, Germany.
EM doerte.luedders@uk-sh.de
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NR 21
TC 9
Z9 11
U1 0
U2 5
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0932-0067
J9 ARCH GYNECOL OBSTET
JI Arch. Gynecol. Obstet.
PD JUN
PY 2011
VL 283
IS 6
BP 1357
EP 1362
DI 10.1007/s00404-010-1594-y
PG 6
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 763DZ
UT WOS:000290536100028
PM 20652284
DA 2026-07-24
ER

PT J
AU Linkov, G
   Cracchiolo, J
   Fielding, AF
   Liu, JC
AF Linkov, Gary
   Cracchiolo, Jennifer
   Fielding, Allen F.
   Liu, Jeffrey C.
TI Facial Nerve Function Preservation With Vacuum-Assisted Closure
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Vacuum-assisted closure; necrotizing fasciitis; facial nerve
   preservation; facial wound
ID NECK; WOUNDS; HEAD; MANAGEMENT
AB Importance: Laboratory and clinical studies have shown that vacuum-assisted closure (VAC) therapy increases wound blood flow and granulation tissue formation and decreases accumulation of fluid and bacteria. Many publications outline the use of VAC dressings in the treatment of sternal, sacral, upper and lower extremity, perineal, and abdominal wounds, but few describe its use in the head and neck region. No report to date has addressed the use of VAC therapy in helping to preserve facial nerve integrity.
   Observations: We present a case of a 64-year-old woman who underwent tissue debridement for necrotizing fasciitis of the left face, neck, and upper chest. She subsequently had exposed facial nerve that was covered with a VAC dressing and demonstrated complete granulation by postoperative day 7 with preservation of function.
   Conclusions and Relevance: This case highlights the effectiveness of VAC in eliminating infectious material and promoting granulation tissue formation. This is the first time that VAC therapy has been shown to maintain neural function when placed directly on functioning cranial nerves.
C1 [Linkov, Gary; Cracchiolo, Jennifer; Liu, Jeffrey C.] Temple Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Philadelphia, PA 19140 USA.
   [Fielding, Allen F.] Temple Univ, Sch Med, Dept Oral & Maxillofacial Surg, Philadelphia, PA 19140 USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple
   University; Pennsylvania Commonwealth System of Higher Education
   (PCSHE); Temple University
RP Linkov, G (通讯作者)，Temple Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, 3401 N Broad St, Philadelphia, PA 19140 USA.
EM Gary.Linkov@tuhs.temple.edu
OI Liu, Jeffrey/0000-0001-8377-0905; Linkov, Gary/0000-0001-8584-5851
CR Byrnside V, 2010, J ORAL MAXIL SURG, V68, P935, DOI 10.1016/j.joms.2009.09.113
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   Yang YH, 2013, J PLAST RECONSTR AES, V66, pE209, DOI 10.1016/j.bjps.2013.03.006
NR 5
TC 7
Z9 8
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD JUL
PY 2014
VL 25
IS 4
BP 1560
EP 1561
DI 10.1097/SCS.0000000000000963
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AN0EZ
UT WOS:000340257800152
PM 24926725
DA 2026-07-24
ER

PT J
AU Whitney, J
   Phillips, L
   Aslam, R
   Barbul, A
   Gottrup, F
   Gould, L
   Robson, MC
   Rodeheaver, G
   Thomas, D
   Stotts, N
AF Whitney, JoAnne
   Phillips, Linda
   Aslam, Rummana
   Barbul, Adrian
   Gottrup, Finn
   Gould, Lisa
   Robson, Martin C.
   Rodeheaver, George
   Thomas, David
   Stotts, Nancy
TI Guidelines for the treatment of pressure ulcers
SO WOUND REPAIR AND REGENERATION
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; CORD INJURY PATIENTS; NURSING-HOME RESIDENTS;
   TISSUE OXYGEN-TENSION; GROWTH-FACTOR; DECUBITUS ULCERS; WOUND-INFECTION;
   BACTERIAL INOCULATION; CALCIUM ALGINATE; RISK-FACTORS
C1 Univ Washington, Seattle, WA 98195 USA.
   Univ Texas, Med Branch, Galveston, TX 77555 USA.
   Sinai Hosp, Baltimore, MD 21215 USA.
   Johns Hopkins Med Inst, Baltimore, MD 21205 USA.
   Univ So Denmark, Odense Hosp, Odense, Denmark.
   Univ S Florida, Tampa, FL USA.
   Univ Virginia, Hlth Syst, Charlottesville, VA USA.
   St Louis Med Ctr, St Louis, MO USA.
   Univ San Francisco, San Francisco, CA 94117 USA.
C3 University of Washington; University of Washington Seattle; University
   of Texas System; University of Texas Medical Branch Galveston; Sinai
   Hospital of Baltimore; Johns Hopkins University; Johns Hopkins Medicine;
   University of Southern Denmark; Odense University Hospital; State
   University System of Florida; University of South Florida; University of
   Virginia; Saint Louis University; University of San Francisco
RP Whitney, J (通讯作者)，Univ Washington, Seattle, WA 98195 USA.
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NR 243
TC 168
Z9 196
U1 0
U2 22
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV-DEC
PY 2006
VL 14
IS 6
BP 663
EP 679
DI 10.1111/j.1524-475X.2006.00175.x
PG 17
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 117KN
UT WOS:000242872100004
PM 17199832
OA Bronze
DA 2026-07-24
ER

PT J
AU Davis, J
   Caruso, DM
   Foster, KN
   Matthews, MR
AF Davis, John
   Caruso, Daniel M.
   Foster, Kevin N.
   Matthews, Marc R.
TI A Novel Approach To Sealing The Denuded Dermis of the Abdominal Wall
   With A Negative Pressure Wound Device After A Decompressive Laparotomy
SO JOURNAL OF BURN CARE & RESEARCH
LA English
DT Article
ID OPEN ABDOMEN; MANAGEMENT; THERAPY
AB The open abdomen is a well-known technique that is applied in a wide variety of clinical situations, including treatment of abdominal compartment syndrome, damage control laparotomy, and severe intraabdominal sepsis. Disease states such as Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis or extensive deep partial and/or full-thickness torso burns involving the abdomen often result in a complete epidermal and partial dermal loss. When ABThera Open Abdomen Negative Pressure Wound Therapy is attempted in these patients, the exposed subcutaneous tissue rarely allows for an adequate seal between the adhesive barrier and the denuded skin. This is because successful placement of negative pressure wound therapy device necessitates having a dry epidermal surface allowing the adhesive tape to actually adhere. The ABThera Open Abdomen Negative Pressure Wound Therapy visceral protective layer was placed over the exposed bowel, followed by the blue perforated foam interface and then the adhesive barrier drape. Over the top of the "less-than-air-tight" adhesive barrier drape was placed a standard isolation transport bowel bag, which was stapled to the dermis, but outside of the previously placed adhesive barrier drape's diameter to "bolster" the adhesive barrier drape, only allowing the suction tube to extend inferiorly. This ABThera Open Abdomen Negative Pressure Wound Therapy ABNPWT held suction, even during multiple adjacent dressing changes, despite the exposed dermis. This case report reveals a unique approach that solves the issue of inadequate seal due to extensive burns to the torso and has significant benefit in burn and wound care practices.
C1 [Davis, John; Caruso, Daniel M.; Matthews, Marc R.] Maricopa Integrated Hlth Syst, Dept Surg, Phoenix, AZ USA.
   [Foster, Kevin N.] Maricopa Integrated Hlth Syst, Arizona Burn Ctr, Dept Surg, 2601 East Roosevelt St, Phoenix, AZ 85008 USA.
C3 Maricopa County General Hospital; Maricopa Integrated Health System;
   Maricopa County General Hospital; Maricopa Integrated Health System
RP Matthews, MR (通讯作者)，Maricopa Integrated Hlth Syst, Arizona Burn Ctr, Dept Surg, 2601 East Roosevelt St, Phoenix, AZ 85008 USA.
EM marc_matthews@dmgaz.org
CR Cheatham ML, 2013, WORLD J SURG, V37, P2018, DOI 10.1007/s00268-013-2080-z
   Chong Si Jack, 2010, Burns, V36, pe127, DOI 10.1016/j.burns.2010.05.007
   Hardin MO, 2012, J BURN CARE RES, V33, P491, DOI 10.1097/BCR.0b013e3182479b00
   Low OW, 2013, BURNS, V39, P1420, DOI 10.1016/j.burns.2013.03.010
   Navsaria P, 2013, WORLD J EMERG SURG, V8, DOI 10.1186/1749-7922-8-4
   Regner JL, 2012, WORLD J SURG, V36, P497, DOI 10.1007/s00268-011-1203-7
   Roberts DJ, 2012, J TRAUMA ACUTE CARE, V73, P629, DOI 10.1097/TA.0b013e31825c130e
NR 7
TC 3
Z9 3
U1 0
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1559-047X
EI 1559-0488
J9 J BURN CARE RES
JI J. Burn Care Res.
PD SEP-OCT
PY 2018
VL 39
IS 5
BP 838
EP 842
DI 10.1097/BCR.0000000000000615
PG 5
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA GS6KY
UT WOS:000443806000031
PM 28661985
DA 2026-07-24
ER

PT J
AU Hallberg, H
   Holmström, H
AF Hallberg, H
   Holmström, H
TI Vaginal construction with skin grafts and vacuum-assisted closure
SO SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND
   SURGERY
LA English
DT Article
DE congenital absence of the vagina; neovagina; vaginal construction;
   vacuum assisted closure; VAC
AB Probably the most common method of constructing a vagina in patients with the Mayer-Rokitansky-Kuster syndrome is the technique popularised by McIndoe and Banister in 1938. A cavity is created between the rectum and urethra-bladder complex and is lined with split-thickness skin grafts. One of the disadvantages of using split-thickness skin grafts is the incidence of late contraction of the neovagina. To avoid this problem full-thickness skin grafts have been used, but their take is less reliable. A new technique to improve the take of skin grafts is the VAC-system (vacuum assisted closure, KCI(R)) which has proved to be particularly valuable in grafting difficult anatomical sites. We have used the VAC-system in the construction of a vagina in one case with split-thickness skin grafts and in two cases with full-thickness skin grafts. In all three cases the take was excellent with little discomfort for the patients. It was not necessary to stent the neovagina in the postoperative period and coitus was possible within a month of operation.
C1 Univ Gothenburg, Sahlgrens Univ Hosp, Dept Plast Surg, SE-41345 Gothenburg, Sweden.
C3 Sahlgrenska University Hospital; University of Gothenburg
RP Holmström, H (通讯作者)，Univ Gothenburg, Sahlgrens Univ Hosp, Dept Plast Surg, SE-41345 Gothenburg, Sweden.
CR Abbe R., 1898, Med. Rec, V54, P836
   HOLMSTROM H, 1976, SCAND J PLAST RECONS, V10, P231, DOI 10.3109/02844317609012974
   McIndoe A H., 1938, J Obstet Gynecol Br Emp, V45, P490, DOI [DOI 10.1111/J.1471-0528.1938.TB11141.X, 10.1111/j.1471-0528.1938.tb11141.x]
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   SADOVE RC, 1988, CLIN PLAST SURG, V15, P443
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
NR 6
TC 25
Z9 32
U1 0
U2 2
PU TAYLOR & FRANCIS AS
PI OSLO
PA CORT ADELERSGT 17, PO BOX 2562, SOLLI, 0202 OSLO, NORWAY
SN 0284-4311
J9 SCAND J PLAST RECONS
JI Scand. J. Plast. Reconstr. Surg. Hand Surg.
PY 2003
VL 37
IS 2
BP 97
EP 101
DI 10.1080/02844310310005621
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 672RV
UT WOS:000182536000006
PM 12755509
DA 2026-07-24
ER

PT J
AU Reiss, N
   Schuett, U
   Kemper, M
   Bairaktaris, A
   Koerfer, R
AF Reiss, Nils
   Schuett, Ulrich
   Kemper, Michael
   Bairaktaris, Andreas
   Koerfer, Reiner
TI New method for sternal closure after vacuum-assisted therapy in deep
   sternal infections after cardiac surgery
SO ANNALS OF THORACIC SURGERY
LA English
DT Editorial Material
ID WOUND-INFECTION
AB The treatment of nonhealing and infected sternotomies after cardiac surgery is a challenging task with increased rates of mortality and morbidity, as well as high costs. Alocal vacuum therapy (ie, the vacuum-assisted closure system) permits the treatment of deep sternal infections due to continuous aspiration and a sealed dressing that stimulates granulation tissue formation. Aggressive vacuum-assisted closure treatment of the sternum in postoperative deep wound infection enhances sternal preservation and the speed of potential rewiring. After some weeks of vacuum-assisted closure therapy, a complete preparation of the substernal structures is necessary. In this context, laceration of the right ventricle is a rare but life-threatening complication. We describe a new technique for sternal closure after vacuum-assisted wound treatment using Nitinol clips ( Praesidia, Bologna, Italy), which can prevent these severe complications. Without any preparation of the substernal tissue the clips can be inserted in the parasternal space with consecutive proper stabilization of the sternum. This new method represents an easy, low-cost and complication-free procedure.
C1 Ruhr Univ Bochum, Heart Ctr N Rhine Westphalia, Clin Thorac & Cardiovasc Surg, Bad Oeynhausen, Germany.
C3 Ruhr University Bochum
RP Reiss, N (通讯作者)，Grp Hosp Pitie Salpetriere, Serv Chirurg Thorac & Cardiovasc, 47-83 Blvd Hop, F-75651 Paris 13, France.
EM nreiss@gmx.de
CR Demaria RG, 2003, HEART SURG FORUM, V6, P434
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Fuchs U, 2005, ANN THORAC SURG, V79, P526, DOI 10.1016/j.athoracsur.2004.08.032
   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
   Klesius AA, 2004, EUR J CARDIO-THORAC, V25, P218, DOI 10.1016/j.ejcts.2003.11.019
   Lu JCY, 2003, EUR J CARDIO-THORAC, V23, P943, DOI 10.1016/S1010-7940(03)00137-4
   Scholl L, 2004, J CARDIAC SURG, V19, P453, DOI 10.1111/j.0886-0440.2004.05002.x
   Totaro P, 2002, EUR J CARDIO-THORAC, V21, P765, DOI 10.1016/S1010-7940(02)00048-9
NR 8
TC 18
Z9 20
U1 0
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD JUN
PY 2007
VL 83
IS 6
BP 2246
EP 2247
DI 10.1016/j.athoracsur.2006.07.077
PG 2
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 172GD
UT WOS:000246791200066
PM 17532448
OA Bronze
DA 2026-07-24
ER

PT J
AU Hou, SL
   Li, XW
   Chen, XS
   Yan, J
   Wang, BH
   Liu, CH
AF Hou, Shulin
   Li, Xiaowen
   Chen, Xushu
   Yan, Jing
   Wang, Bihua
   Liu, Chunhua
TI Application of Negative Pressure Wound Therapy in Neonatal Bone-Exposed
   Wounds: Nursing Interventions and Clinical Outcomes
SO NURSING IN CRITICAL CARE
LA English
DT Article
DE coccygectomy; negative pressure wound therapy; neonate; sacral bone
   exposure; Sacrococcygeal teratoma
ID SACROCOCCYGEAL TERATOMA; CHILDREN; CLOSURE
AB Sacrococcygeal teratoma (SCT) is the most common extragonadal germ cell tumor in neonates, with an incidence of approximately 1 in 35,000-40,000 live births. Postoperative management of SCT poses significant challenges due to the extensive surgical field and the anatomical proximity of the lesion to the perianal region. Altman type IV SCT, characterized by its entirely intrapelvic location and higher risk of malignancy, often requires radical resection in conjunction with coccygectomy. This procedure frequently results in deep tissue defects and exposes the sacral bone, increasing the risk of secondary infection. Conventional flap reconstruction is often impractical in neonates due to limited donor tissue availability, tissue fragility, and a high risk of complications. Negative Pressure Wound Therapy (NPWT) has demonstrated efficacy in promoting wound healing through multiple mechanisms, yet its application in neonatal wounds with exposed bone has not been previously reported. The aim of this case study is to summarise the experience of successfully treating postoperative SCT wounds complicated by sacral bone exposure using negative pressure wound therapy (NPWT) in combination with a sodium carboxymethylcellulose silver dressing (CMC-Ag). NPWT in combination with a sodium CMC-Ag. After 43 days of intensive treatment and care, the child recovered and was discharged. The insights gained from this case can provide valuable references for nursing practice in pediatric intensive care units. Relevance to Clinical Practice Offering a novel treatment strategy for this challenging clinical scenario.
C1 [Hou, Shulin; Li, Xiaowen; Chen, Xushu; Yan, Jing; Wang, Bihua; Liu, Chunhua] Sichuan Univ, West China Univ Hosp 2, Dept Neonatol Nursing, Chengdu, Peoples R China.
   [Hou, Shulin; Li, Xiaowen; Chen, Xushu; Yan, Jing; Wang, Bihua; Liu, Chunhua] Sichuan Univ, Key Lab Birth Defects & Related Dis Women & Childr, Minist Educ, Chengdu, Peoples R China.
C3 Sichuan University; Sichuan University
RP Li, XW (通讯作者)，Sichuan Univ, West China Univ Hosp 2, Dept Neonatol Nursing, Chengdu, Peoples R China.; Li, XW (通讯作者)，Sichuan Univ, Key Lab Birth Defects & Related Dis Women & Childr, Minist Educ, Chengdu, Peoples R China.
EM xiaowenli@scu.edu.cn
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NR 27
TC 1
Z9 1
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1362-1017
EI 1478-5153
J9 NURS CRIT CARE
JI Nurs. Crit. Care
PD NOV
PY 2025
VL 30
IS 6
AR e70250
DI 10.1111/nicc.70250
PG 6
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA G2507
UT WOS:001624354200009
PM 41277281
DA 2026-07-24
ER

PT J
AU Nelson, JA
   Kim, EM
   Serletti, JM
   Wu, LC
AF Nelson, Jonas A.
   Kim, Elizabeth M.
   Serletti, Joseph M.
   Wu, Liza C.
TI A Novel Technique for Lower Extremity Limb Salvage: The Vastus Lateralis
   Muscle Flap with Concurrent Use of the Vacuum-Assisted Closure Device
SO JOURNAL OF RECONSTRUCTIVE MICROSURGERY
LA English
DT Article
DE Cook Doppler; vastus lateralis; vacuum-assisted closure device
ID MICROVASCULAR FREE FLAPS; IMPLANTABLE DOPPLER; EXPERIENCE;
   RECONSTRUCTION; PROBE
AB Free tissue transfer is an essential component of lower extremity limb reconstruction and has dramatically improved salvage attempts. In this report, we examine the use of the underutilized free vastus lateralis muscle flap and describe our treatment protocol that involves a novel application for the vacuum-assisted closure device in an effort to reduce edema and congestion in lower extremity limb salvage. Thirteen patients underwent reconstruction with 14 vastus lateralis flaps with closure occurring on average 35.2 days after injury and an average case duration of 4:34 hours. We report one flap failure, one superficial abscess, and one donor site hematoma. All patients were ambulatory at 6 months. Our early experience using this underutilized flap and novel protocol demonstrate successful lower extremity reconstruction with few complications, and good function and contour. Given its advantages, this versatile flap should be included as an option in lower extremity limb salvage operations.
C1 [Nelson, Jonas A.; Kim, Elizabeth M.; Serletti, Joseph M.; Wu, Liza C.] Univ Penn, Sch Med, Div Plast Surg, Philadelphia, PA 19104 USA.
C3 University of Pennsylvania
RP Wu, LC (通讯作者)，Univ Penn, Sch Med, Div Plast Surg, 10 Penn Tower,3400 Spruce St, Philadelphia, PA 19104 USA.
EM Liza.Wu@uphs.upenn.edu
OI Nelson, Jonas/0000-0003-0329-4422
FU Doris Duke Clinical Research Fellowship
FX This project was made possible in part by the Doris Duke Clinical
   Research Fellowship.
CR Bosse MJ, 2002, NEW ENGL J MED, V347, P1924, DOI 10.1056/NEJMoa012604
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NR 14
TC 13
Z9 14
U1 0
U2 0
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 0743-684X
EI 1098-8947
J9 J RECONSTR MICROSURG
JI J. Reconstr. Microsurg.
PD SEP
PY 2010
VL 26
IS 7
BP 427
EP 431
DI 10.1055/s-0030-1251561
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 637GL
UT WOS:000280805300001
PM 20309803
DA 2026-07-24
ER

PT J
AU Lim, XX
   Zhang, L
   Hong, QT
   Yong, EM
   Neo, S
   Chandrasekar, S
   Tan, GWL
   Lo, ZJ
AF Lim, Xuxin
   Zhang, Li
   Hong, Qiantai
   Yong, Enming
   Neo, Shufen
   Chandrasekar, Sadhana
   Tan, Glenn Wei Leong
   Lo, Zhiwen Joseph
TI Novel home use of mechanical negative pressure wound therapy in diabetic
   foot ulcers
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE diabetes; diabetic foot wounds; home therapy; leg wounds; limb salvage;
   mechanical negative pressure wound therapy; NPWT; outcomes; ulcers;
   wound; wound care; wound healing
ID MULTICENTER; DEVICE
AB Objective: Mechanical negative pressure wound therapy is an ultraportable, light weight and disposable single-use device that has been shown to promote wound healing. This study evaluated home use of a mechanically powered negative pressure wound therapy (NPWT) in diabetic foot wounds.
   Methods: Patients underwent revascularisation and/or debridement or amputation before starting mechanical NPWT. Wound outcomes and images of the wounds were recorded at each follow-up visit by the wound nurse. Patients were followed up until wound closure or end of therapy.
   Results: A total of 12 patients (each with one wound) were included in the study. Of the 12 wounds, 33.3% (n=4) of wounds achieved primary wound closure while the remaining 66.6% (n=8) of wounds demonstrated a mean wound size reduction of 37.5 +/- 0.13%. Of the closed wounds, mean time to healing was 4.75 +/- 2.50 weeks. There was 100% limb salvage with no further debridement or amputations, and no 30-day unplanned readmissions. Mean length of hospital stay before starting home NPWT was 9.75 +/- 6.31 days. Mean number of NPWT changes was 8.33 +/- 2.67 sessions, while mean duration of therapy was 4.0 +/- 1.54 weeks. Mean cost of home NWPT therapy was US$1904 +/- 731 per patient.
   Conclusion: The home use of mechanically powered NPWT in diabetic foot wounds demonstrated excellent wound healing rates and 100% limb salvage, with no complications.
C1 [Lim, Xuxin; Zhang, Li; Hong, Qiantai; Yong, Enming; Neo, Shufen; Chandrasekar, Sadhana; Tan, Glenn Wei Leong] Tan Tock Seng Hosp, Dept Gen Surg, Vasc Surg Serv, Singapore, Singapore.
   [Lo, Zhiwen Joseph] Woodlands Hlth, Vasc Surg Serv, Dept Surg, Singapore, Singapore.
C3 Tan Tock Seng Hospital
RP Lim, XX (通讯作者)，Tan Tock Seng Hosp, Dept Gen Surg, Vasc Surg Serv, Singapore, Singapore.
EM meghan.lim@mohh.com.sg
RI ; Yong, Enming/LXB-4566-2024
OI Chanasekar, Sadhana/0000-0002-3650-8020; Yong,
   Enming/0000-0002-9461-0066
CR Ang Y, 2017, PROC SINGAP HEALTHC, V26, P76, DOI 10.1177/2010105816663521
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   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Bommer C, 2018, DIABETES CARE, V41, P963, DOI 10.2337/dc17-1962
   Cuomo R, 2021, J INVEST SURG, V34, P335, DOI 10.1080/08941939.2019.1616009
   Dalla Paola L, 2013, INT WOUND J, V10, P25, DOI 10.1111/iwj.12174
   Dowsett C, 2013, BR J COMMUNITY NURS, pS12, DOI [10.12968/bjcn.2013.18.sup6.s6, DOI 10.12968/BJCN.2013.18.SUP6.S6]
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NR 22
TC 6
Z9 7
U1 0
U2 11
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD DEC
PY 2021
VL 30
IS 12
BP 1006
EP 1010
DI 10.12968/jowc.2021.30.12.1006
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA XN8PR
UT WOS:000729761400007
PM 34882000
DA 2026-07-24
ER

PT J
AU Andrews, BT
   Smith, RB
   Hoffman, HT
   Funk, GF
AF Andrews, Brian T.
   Smith, Russell B.
   Hoffman, Henry T.
   Funk, Gerry F.
TI Orocutaneous and pharyngocutaneous fistula closure using a
   vacuum-assisted closure system
SO ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
LA English
DT Article
DE fistula closure; salivary leak; topical negative pressure dressing;
   vacuum-assisted closure
ID ENTEROCUTANEOUS FISTULAS; RADIATION-THERAPY; WOUND CONTROL; MANAGEMENT;
   COMPLICATIONS; LARYNGECTOMY; SURGERY; HEAD
AB Objectives: The vacuum-assisted closure (VAC) system is a topical negative pressure dressing that has been used extensively to manage a multitude of complicated wounds, including enterocutaneous fistula. We hypothesize that the VAC system may also facilitate the closure of orocutaneous and pharyngocutaneous fistulas.
   Methods: A retrospective chart review was performed.
   Results: Three patients were identified. Two patients developed fistulas after undergoing salvage laryngectomy, and 1 patient developed a fistula after having a hemiglossectomy defect reconstructed by a radial forearm free flap. The VAC system was successful in closing the fistula in 2 of the 3 patients. Complete fistula closure took 3 and 11 days in the 2 cases. The 1 failure of fistula closure was due to poor collapsibility of the neck tissue along the fistula tract caused by fibrosis following prior radiotherapy.
   Conclusions: The VAC system is a feasible treatment option for closing head and neck fistulas, especially when collapsible tissue is present at the fistula site.
C1 [Andrews, Brian T.; Smith, Russell B.; Hoffman, Henry T.; Funk, Gerry F.] Univ Iowa, Coll Med, Dept Otolaryngol Head & Neck Surg, Iowa City, IA 52242 USA.
C3 University of Iowa
RP Funk, GF (通讯作者)，Univ Iowa, Coll Med, Dept Otolaryngol Head & Neck Surg, 21200 Pomerantz Pavil,200 Hawkins Dr, Iowa City, IA 52242 USA.
OI Hoffman, Henry/0000-0003-4486-855X; Andrews, Brian/0000-0003-3994-6808
CR Andrews BT, 2006, HEAD NECK-J SCI SPEC, V28, P974, DOI 10.1002/hed.20496
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   de Weerd L, 2007, ANN PLAS SURG, V58, P580, DOI 10.1097/01.sap.0000237643.45125.8b
   Draus JM, 2006, SURGERY, V140, P570, DOI 10.1016/j.surg.2006.07.003
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NR 15
TC 34
Z9 42
U1 0
U2 1
PU ANNALS PUBL CO
PI ST LOUIS
PA 4507 LACLEDE AVE, ST LOUIS, MO 63108 USA
SN 0003-4894
J9 ANN OTO RHINOL LARYN
JI Ann. Otol. Rhinol. Laryngol.
PD APR
PY 2008
VL 117
IS 4
BP 298
EP 302
DI 10.1177/000348940811700410
PG 5
WC Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology
GA 288JU
UT WOS:000254983500010
PM 18478840
DA 2026-07-24
ER

PT J
AU Nguyen, SH
   Defnet, AM
   Pati, BA
   Russell, DM
   Gillern, SM
   Lin, E
   Sullivan, PS
   Yheulon, C
AF Nguyen, Scott H.
   Defnet, Ann M.
   Pati, Brooke A.
   Russell, Dylan M.
   Gillern, Suzanne M.
   Lin, Edward
   Sullivan, Patrick S.
   Yheulon, Christopher
TI Role of Negative Pressure Wound Therapy When Performing Elective Open
   Colectomy
SO SURGICAL INFECTIONS
LA English
DT Article
DE colectomy; negative pressure wound therapy; surgical site infection;
   wound complication; wound vac
ID SURGICAL SITE INFECTIONS; SURGERY
AB Background: The impact of negative pressure wound therapy (NPWT) as an adjunct to colorectal surgery is largely unknown. The purpose of this study was to determine whether NPWT impacts wound complications during elective open colectomy.
   Methods: The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) and colectomy targeted procedure databases were queried from 2012-2018 for patients undergoing non-emergent planned open colectomies. Groups were propensity score matched for anastomosis type (ileo-colic, colo-colic, colo-rectal), age, body mass index (BMI), diabetes, smoking, steroid use, wound classification, American Society of Anesthesiologists (ASA) class, operative time, and wound layers closed. Wound complications were defined as superficial surgical site infection (SSI), deep incisional SSI, and dehiscence.
   Results: A total of 15,770 patients were identified; 92 underwent simultaneous NPWT (0.58%). Non-NPWT patients were matched at a 5:1 ratio, producing 460 comparisons. There was no difference in wound complications (8.26% non-NPWT vs. 6.52% NPWT; p = 0.574). In addition, there were no differences in wound complications when only including patients who had NPWT placed over closed skin (9.11% non-NPWT vs. 7.25% NPWT; p = 0.789). On multivariable analysis, NPWT was not associated with wound complications (odds ratio [OR] 0.79; 95% confidence interval [CI], 0.37-1.69).
   Conclusions: Negative pressure wound therapy does not reduce wound complications in open elective colectomies. Large randomized studies and more granular data are needed to ascertain if there is any benefit in select patient populations.
C1 [Nguyen, Scott H.; Pati, Brooke A.; Russell, Dylan M.; Gillern, Suzanne M.; Yheulon, Christopher] Tripler Army Med Ctr, Dept Surg, 1 Jarrett White Rd, Honolulu, HI 96859 USA.
   [Defnet, Ann M.; Lin, Edward; Yheulon, Christopher] Emory Univ, Div GI & Gen Surg, Atlanta, GA 30322 USA.
   [Sullivan, Patrick S.] Emory Univ, Div Surg Oncol, Atlanta, GA 30322 USA.
C3 Tripler Army Medical Center; United States Department of Defense; United
   States Army; Emory University; Emory University
RP Nguyen, SH (通讯作者)，Tripler Army Med Ctr, Dept Surg, 1 Jarrett White Rd, Honolulu, HI 96859 USA.
EM scott.h.nguyen.mil@mail.mil
RI ; Yheulon, Christopher/AAS-6917-2020
OI Russell, Dylan/0000-0002-9543-9897; 
CR Austin PC, 2010, AM J EPIDEMIOL, V172, P1092, DOI 10.1093/aje/kwq224
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   Clavien PA, 2009, ANN SURG, V250, P187, DOI 10.1097/SLA.0b013e3181b13ca2
   Cone MM, 2012, J GASTROINTEST SURG, V16, P1212, DOI 10.1007/s11605-012-1860-3
   DeCarbo WT, 2010, J FOOT ANKLE SURG, V49, P299, DOI 10.1053/j.jfas.2010.01.002
   Gantz O, 2019, AM SURGEON, V85, P142
   Kobayashi M, 2008, WORLD J SURG, V32, P1142, DOI 10.1007/s00268-008-9536-6
   Konishi T, 2006, ANN SURG, V244, P758, DOI 10.1097/01.sla.0000219017.78611.49
   Mihaljevic AL, 2015, TRIALS, V16, DOI 10.1186/s13063-015-0995-4
   Murphy PB, 2019, ANN SURG, V270, P38, DOI 10.1097/SLA.0000000000003111
   Novitsky YW, 2005, AM SURGEON, V71, P627
   Orgill DP, 2013, INT WOUND J, V10, P15, DOI 10.1111/iwj.12170
   Panayi AC, 2017, World Journal of Dermatology, V6, P1, DOI [10.5314/wjd.v6.i1.1, 10.5314/wjd.v6.i1.1, DOI 10.5314/WJD.V6.I1.1]
   Pellino G, 2015, UPDATES SURG, V67, P235, DOI 10.1007/s13304-015-0298-z
   Randolph J.J., 2014, PRACTICAL ASSESSMENT, V19
   Regner Justin L, 2018, Proc (Bayl Univ Med Cent), V31, P25, DOI [10.1080/08998280.2017.1400312, 10.1080/08998280.2017.1400312]
   Smith RL, 2004, ANN SURG, V239, P599, DOI 10.1097/01.sla.0000124292.21605.99
   Srinivas TR, 2015, TRANSPLANTATION, V99, P17, DOI 10.1097/TP.0000000000000581
   Tyagi V, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.7394
   Webb MA, 2019, AM J SURG, V217, P948, DOI 10.1016/j.amjsurg.2018.12.019
NR 20
TC 3
Z9 3
U1 0
U2 0
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD JUN 1
PY 2021
VL 22
IS 5
BP 562
EP 567
DI 10.1089/sur.2020.183
EA NOV 2020
PG 6
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA SL7FG
UT WOS:000593364100001
PM 33232647
DA 2026-07-24
ER

PT J
AU Rettig, MJ
   Lischer, CJ
AF Rettig, M. J.
   Lischer, C. J.
TI Treatment of chronic septic osteoarthritis of the antebrachiocarpal
   joint with a synovial-cutaneous fistula utilising arthroscopic lavage
   combined with ultrasonic assisted wound therapy and vacuum assisted
   closure with a novel wound lavage system
SO EQUINE VETERINARY EDUCATION
LA English
DT Article
DE horse; synovial fistula; septic arthritis; multiresistant
   microorganisms; fistulating wound; chronic wound
ID INTERSYNOVIAL FISTULA; LIMB PERFUSION; HORSE; DEBRIDEMENT;
   MARBOFLOXACIN; MANAGEMENT; AMIKACIN; EFFICACY; HERNIA; FLUID
AB This case report describes the successful management of a chronic multidrug resistant infection of the antebrachiocarpal joint with a synovial-cutaneous fistula 7 weeks after initial trauma in a 14-year-old Icelandic stallion. Resolution of the multiresistant Enterobacter cloacae (extended-spectrum blactamase) infection from the joint and complete closure of the fistula was achieved by arthroscopic lavage under general anaesthesia repeated on 3 occasions, surgical debridement, ultrasound assisted wound therapy and vacuum assisted closure. Lavage of the wound with the vacuum assisted closure in place was facilitated via the novel VeraFlo instillation system consisting of specially designed therapeutic regulated accurate care pad tubing. The combination of these therapies resulted in resolution of the septic arthritis and fistula. Six weeks after admission the horse was discharged from the hospital with a completely healed wound and was not lame at a walk.
C1 [Rettig, M. J.; Lischer, C. J.] Free Univ Berlin, Fac Vet Med, Equine Clin, Berlin, Germany.
C3 Free University of Berlin
RP Rettig, MJ (通讯作者)，Free Univ Berlin, Fac Vet Med, Equine Clin, Berlin, Germany.
EM matthias.rettig@fu-berlin.de
CR Baxter G.M., 2008, Em Equine wound managemente, V2nd, P463
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NR 28
TC 6
Z9 7
U1 0
U2 3
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0957-7734
EI 2042-3292
J9 EQUINE VET EDUC
JI Equine Vet. Educ.
PD JAN
PY 2017
VL 29
IS 1
BP 27
EP 32
DI 10.1111/eve.12390
PG 6
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA EK1LU
UT WOS:000393687700006
DA 2026-07-24
ER

PT J
AU Klein, RJ
AF Klein, Robert J.
TI Managing Wound Dehiscence With Mechanical Negative Pressure Wound
   Therapy: A Case Report
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE mechanical negative pressure wound therapy; wound dehiscence; diabetic
   foot ulceration; negative pressure wound therapy; ray resection
AB Mechanical negative pressure wound therapy (mNPWT) is commonly used in the management of a variety of wounds, including diabetic foot ulcerations, surgical wounds, venous ulcerations, and wound dehiscence. This mechanically powered, disposable modality can be used to manage wounds in the outpatient setting and has been shown to be an effective wound care option when transitioning patients from the inpatient to outpatient setting and continuing NPWT for wound care. Mechanical NPWT helps promote wound healing by decreasing edema and via removal of tissue debris and exudate. Traditional NPWT is bulky, is often noisy, and requires a power source. A mechanically powered, disposable, easily applied, off-the-shelf mNPWT device is available for patients with small- to medium-sized wounds with mild to moderate exudate. The disposable mNPWT device provides -125 mm Hg pressure, is silent and small, can be worn under clothes, and allows the patient to be fully ambulatory, thus, more mobile. The mNPWT device tubing can be cut to fit to enable safer ambulation than the powered system and to enable the patient to work and enjoy social activities without a medical device showing. This single case study of a patient with chronic diabetic foot ulcerations of the medial first metatarsal head and dorsal proximal interphalangeal joints of the second and third toes of the left foot, which had not been successfully treated with conservative care and had been present for more than 1 year.
C1 [Klein, Robert J.] Wound Healing & Hyperbar Oxygen Ctr, Greenville, SC USA.
   [Klein, Robert J.] Univ South Carolina, Sch Med, Greenville, SC USA.
RP Klein, RJ (通讯作者)，200 Patewood Dr,Suite C300, Greenville, SC 29615 USA.
EM robklein63@gmail.com
CR Fong KD, 2010, WOUNDS, V22, P230
   Fong KD, 2010, PLAST RECONSTR SURG, V125, P1362, DOI 10.1097/PRS.0b013e3181d62b25
   Landers S, 2016, HOME HLTH CARE MAN P, V28, P262, DOI 10.1177/1084822316666368
   Lerman Bruce, 2010, J Diabetes Sci Technol, V4, P825
   Nussbaum SR, 2018, VALUE HEALTH, V21, P27, DOI 10.1016/j.jval.2017.07.007
   Tettelbach William, 2019, Wounds, V31, pS1
NR 6
TC 2
Z9 2
U1 2
U2 8
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD DEC
PY 2021
VL 33
IS 12
BP E75
EP E78
DI 10.25270/wnds/2021.e7578
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA XN8PK
UT WOS:000729760700001
PM 34882095
DA 2026-07-24
ER

PT J
AU Giudicelli, G
   Rossetti, A
   Scarpa, C
   Buchs, NC
   Hompes, R
   Guy, RJ
   Ukegjini, K
   Morel, P
   Ris, F
   Adamina, M
AF Giudicelli, Guillaume
   Rossetti, A.
   Scarpa, C.
   Buchs, N. C.
   Hompes, R.
   Guy, R. J.
   Ukegjini, K.
   Morel, P.
   Ris, F.
   Adamina, M.
TI Prognostic Factors for Enteroatmospheric Fistula in Open Abdomen Treated
   with Negative Pressure Wound Therapy: a Multicentre Experience
SO JOURNAL OF GASTROINTESTINAL SURGERY
LA English
DT Article; Proceedings Paper
CT 103rd Annual Congress of the Swiss-Society-of-Surgery
CY JUN 01-03, 2016
CL Bern, SWITZERLAND
SP Swiss Soc Surg
DE Open abdomen; Negative pressure wound therapy; Enteroatmospheric fistula
ID ABDOMINAL COMPARTMENT SYNDROME; UPDATED CONSENSUS DEFINITIONS;
   CLINICAL-PRACTICE GUIDELINES; INTRAABDOMINAL HYPERTENSION; MANAGEMENT;
   CLASSIFICATION; SOCIETY; CLOSURE; COMPLICATIONS; LAPAROTOMY
AB Background Reductions in mortality were reported with negative pressure wound therapy for laparostomy. However, some authors have voiced concern over an increased risk of enteroatmospheric fistulae. In this retrospective study, we hypothesized that surgical and metabolic derangements could increase the incidence of enteroatmospheric fistulae. We aimed to assess our experience and report long-term outcomes.
   Methods A multicentre review of all patients with a laparostomy managed with negative pressure wound therapy between 2005 and 2015 was undertaken. Features associated with enteroatmospheric fistulae were included in multivariate logistic regression.
   Results Fifty-seven patients were treated according to uniform protocol. Fourteen per cent (8/57) presented enteroatmospheric fistulae. Mesenteric ischaemia and preoperative arterial serum lactate > 3.5 mmol/L were associated with a significantly increased risk of enteroatmospheric fistulae. Preoperative arterial serum lactate > 3.5 mmol/L was an independent predictor of enteroatmospheric fistulae with an odds ratio of 12.41 (95% CI 1.54-99.99). All mesenteric ischaemia patients with anastomosis (5/15) presented enteroatmospheric fistulae. In-hospital mortality was 26.3% (15/57). One-year mortality was 33.3% (19/57). Incisional hernia rate was 5.2% (2/38) after 14.2 (2.4-56.3) months of follow-up.
   Discussion Mesenteric ischaemia increases the risk of enteroatmospheric fistulae. Anastomosis should only be created in revascularized patients. When mesenteric vascularization is not restored, diversion is advised.
C1 [Giudicelli, Guillaume; Scarpa, C.; Buchs, N. C.; Morel, P.; Ris, F.] Geneva Univ Hosp, Div Visceral Surg, Dept Surg, Gabrielle Perret Gentil 4, CH-1211 Geneva 14, Switzerland.
   [Rossetti, A.; Ukegjini, K.] Cantonal Hosp Sankt Gallen, Dept Visceral Surg, St Gallen, Switzerland.
   [Buchs, N. C.; Hompes, R.; Guy, R. J.] Oxford Univ Hosp, Churchill Hosp, Dept Colorectal Surg, Oxford, England.
   [Adamina, M.] Kantonsspital Winterthur, Div Visceral & Thorac Surg, Dept Surg, Winterthur, Switzerland.
   [Adamina, M.] Univ Basel, Basel, Switzerland.
C3 Kantonsspital St. Gallen; University of Oxford; University of Basel
RP Giudicelli, G (通讯作者)，Geneva Univ Hosp, Div Visceral Surg, Dept Surg, Gabrielle Perret Gentil 4, CH-1211 Geneva 14, Switzerland.
EM guillaume.giudicelli@hcuge.ch
RI Adamina, Michel/J-8034-2019; Giudicelli, Guillaume/AAY-3512-2021; Ris,
   Frederic/H-7030-2019; Hompes, Roel/AAN-6249-2020
OI Adamina, Michel/0000-0002-5464-6953; Buchs, Nicolas/0000-0001-9255-3929;
   Giudicelli, Guillaume/0000-0002-0213-9335; Ris,
   Frederic/0000-0001-7421-6101; Hompes, Roel/0000-0001-6094-8950
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NR 28
TC 17
Z9 27
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1091-255X
EI 1873-4626
J9 J GASTROINTEST SURG
JI J. Gastrointest. Surg.
PD AUG
PY 2017
VL 21
IS 8
BP 1328
EP 1334
DI 10.1007/s11605-017-3453-7
PG 7
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Gastroenterology & Hepatology; Surgery
GA FB3EV
UT WOS:000406026400017
PM 28536807
DA 2026-07-24
ER

PT J
AU Joubert, C
   Sellier, A
   Morvan, JB
   Beucler, N
   Bordes, J
   Dagain, A
AF Joubert, Christophe
   Sellier, A.
   Morvan, J-B
   Beucler, N.
   Bordes, J.
   Dagain, A.
TI Vacuum-assisted closure (VAC) for craniocerebral wounds in severely
   injured patients: technical note of a damage control procedure
SO JOURNAL OF THE ROYAL ARMY MEDICAL CORPS
LA English
DT Article
DE vacuum-assisted closure; penetrating craniocerebral trauma; severe
   traumatic brain injury; damage control; trauma management
ID GUNSHOT WOUNDS; BRAIN; HEAD; MANAGEMENT; SCALP
AB The management of a craniocerebral wound (CCW) remains challenging, particularly in a severely injured patient. Considering the complexity of the multilayer insult and damage control care in an unstable patient, every procedure performed should promptly benefit the patient. We report an illustrative case of a patient with a gunshot wound to the head that resulted in a CCW for which we applied vacuum-assisted closure (VAC) therapy according to damage control principles. We describe the technical approach and discuss the indications, results and technique by considering the literature available. VAC can be used for CCWs, particularly for large defects in selected patients according to clinical and CT evaluations following immediate resuscitation. In severely injured and unstable patients, VAC aims to delay definitive reconstructive and time-consuming treatment. Interestingly, it appears to be a safe treatment based on the previously described-but not exclusively trauma-cases with no secondary cerebrospinal fluid leakage encountered.
C1 [Joubert, Christophe; Sellier, A.; Beucler, N.; Dagain, A.] Mil Teaching Hosp St Anne, Neurosurg, Toulon Armees, France.
   [Morvan, J-B] Mil Teaching Hosp St Anne, Ear Nose Throat & Cervicofacial Surg, Toulon Armee, France.
   [Bordes, J.] HIA St Anne, Anesthesiol & Intens Care Unit, Toulon Armees, France.
RP Joubert, C (通讯作者)，Neurosurg, F-83000 Toulon, France.
EM christophe.joubert@neurochirurgie.fr
RI Morvan, Jean-baptiste/N-7724-2015; Joubert, Christophe/AAU-4807-2020
OI BEUCLER, Nathan/0000-0003-3047-4234; Joubert,
   Christophe/0000-0002-8935-6710
CR Aarabi B, 2001, J TRAUMA, V51, pS3
   Afifi AM, 2010, J CRANIOFAC SURG, V21, P1205, DOI 10.1097/SCS.0b013e3181e17c1e
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   Andrews BT, 2006, HEAD NECK-J SCI SPEC, V28, P974, DOI 10.1002/hed.20496
   Bordes J, 2017, INJURY, V48, P1047, DOI 10.1016/j.injury.2016.11.023
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   CAVALIERE R, 1988, ACTA NEUROCHIR, V94, P133, DOI 10.1007/BF01435866
   Dagain A, 2018, NEUROSURG FOCUS, V45, DOI 10.3171/2018.9.FOCUS18368
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   Hofbauer M, 2010, J TRAUMA, V69, P770, DOI 10.1097/TA.0b013e3181c81d7d
   Kim EK, 2008, J CRANIOFAC SURG, V19, P1577, DOI 10.1097/SCS.0b013e3181897376
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Powers AK, 2013, J NEUROSURG, V118, P302, DOI 10.3171/2012.10.JNS112241
   Prince N, 2015, ANN PLAS SURG, V74, pS218, DOI 10.1097/SAP.0000000000000374
   Satteson ES, 2015, J CRANIOFAC SURG, V26, pE599, DOI 10.1097/SCS.0000000000002047
NR 16
TC 5
Z9 7
U1 0
U2 5
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 0035-8665
EI 2052-0468
J9 J ROY ARMY MED CORPS
JI J. R. Army Med. Corps
PD DEC
PY 2019
VL 165
IS 6
DI 10.1136/jramc-2019-001201
PG 3
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA JT1MJ
UT WOS:000500761800001
PM 30992341
DA 2026-07-24
ER

PT J
AU Loos, B
   Kopp, J
   Kneser, U
   Weyand, M
   Horch, RE
AF Loos, B
   Kopp, J
   Kneser, U
   Weyand, M
   Horch, RE
TI The importance of vacuum therapy in the treatment of sternal
   osteomyelitis from the plastic surgeons point of view
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nurnberg, GERMANY
DE sternal osteomyelitis; plastic reconstruction; wound conditioning;
   vacuum therapy; tissue transfer
ID MUSCLE FLAPS; ASSISTED CLOSURE; WOUND CONTROL; FOUNDATION; EXPERIENCE
AB Background: Since its introduction in 1997 the vacuum assisted closure therapy has gained widespread and is for its indications international accepted. It is also well established in the treatment of sternal infections a dreaded complication after median sternotomy in cardiac surgery. The well known positive effects of the vacuum therapy act as a dignified cleaning procedure between debridement and plastic coverage or as a temporarily closure method if the first debridement was properbly not sufficient. Method and patients: Between January 2003 and December 2005 twenty-eight patients with advanced sternal infection after median sternotomy were treated by radical debridement, vacuum assisted closure therapy and definitive plastic coverage by muscle flaps. In this article three patients are exemplarily introduced. Results: In all patients a sufficient plastic coverage was achieved after radical debridement an vacuum assisted closure therapy. The patients received a pedicaled muscle flap. Stable wound condition with no signs of a recurrend sternal infection were observed in all patients. Discussion: Vacuum assisted closure therapy acts as a link between radical Debridement and definitive plastic coverage in prolonged sternal infection after median sternotomy. Before the invention of V.A.C.(R) dressing changes were obliged every day in patients with deep sternal infection. The V.A.C.(R) therapy reduces the frequency of this painful dressing changes significantly and on this behalf makes life more comfortable for this mostly multimorbide patients.
C1 Univ Erlangen Nurnberg, Chirurg Klin, Abt Plast & Handchirurg, D-91054 Erlangen, Germany.
   Univ Erlangen Nurnberg, Klin Herzchirurg, D-91054 Erlangen, Germany.
C3 University of Erlangen Nuremberg; University of Erlangen Nuremberg
RP Loos, B (通讯作者)，Univ Erlangen Nurnberg, Chirurg Klin, Abt Plast & Handchirurg, Krankenhausstr 12, D-91054 Erlangen, Germany.
EM Bernd.Loos@chir.imed.uni-erlangen.de
RI Horch, Raymund E/H-8128-2019
OI Horch, Raymund E/0000-0002-6561-2353
CR Agarwal JP, 2005, PLAST RECONSTR SURG, V116, P1035, DOI 10.1097/01.prs.0000178401.52143.32
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   BJERNO T, 1990, UGESKRIFT LAEGER, P3699
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NR 15
TC 7
Z9 8
U1 0
U2 0
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S124
EP S128
DI 10.1055/s-2006-921425
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 034DB
UT WOS:000236904100029
PM 16575662
DA 2026-07-24
ER

PT J
AU Ekwobi, CC
   Culliford, A
   Spector, J
   Levine, J
AF Ekwobi, C. C.
   Culliford, A.
   Spector, J.
   Levine, J.
TI Re:: A novel technique for vacuum assisted closure device application in
   non-contiguous wounds, by A.!Culliford IV, J.!Spector, J.!Levine,
   Journal of Plastic, Reconstructive & Aesthetic Surgery, 2007;60:99-100
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Letter
C1 Royal Preston Hosp, Dept Plast Surg, Preston PR2 9HT, Lancs, England.
C3 Royal Preston Hospital
RP Ekwobi, CC (通讯作者)，Royal Preston Hosp, Dept Plast Surg, Sharoe Green Lane, Fulwood, Preston PR2 9HT, Lancs, England.
EM cekwobi@toucansurf.com
CR Culliford AT, 2007, J PLAST RECONSTR AES, V60, P99, DOI 10.1016/j.bjps.2006.03.070
NR 1
TC 1
Z9 1
U1 0
U2 0
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PY 2007
VL 60
IS 11
BP 1268
EP 1268
DI 10.1016/j.bjps.2007.01.083
PG 1
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 232SO
UT WOS:000251039900020
PM 17765671
DA 2026-07-24
ER

PT J
AU Sun, HX
   Fu, J
   Wen, B
   Zhang, LL
   Zhao, Y
   Li, X
   Li, ZJ
   Tang, LH
   Xin, JB
AF Sun, Haoxuan
   Fu, Jun
   Wen, Bo
   Zhang, Lili
   Zhao, Yi
   Li, Xiang
   Li, Zhijun
   Tang, Lihua
   Xin, Jiangbo
TI Original Negative pressure sealing drainage technology combined with
   adequate irrigation for oral and maxillofacial space infection can
   improve serum inflammatory factor levels
SO AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
LA English
DT Article
DE Vacuum sealing drainage; full irrigation treatment; oral and
   maxillofacial space infection; clinical efficacy; inflammatory factors
ID COMPLICATIONS; MANAGEMENT; WOUNDS
AB Objective: This study aimed to assess the clinical efficacy of combining vacuum sealing drainage with full irrigation in managing oral and maxillofacial space infections and its impact on serum inflammatory factor levels in patients. Methods: We retrospectively analyzed data from 110 patients with oral and maxillofacial space infections treated at our hospital between February 2018 and March 2022. Among them, 50 patients underwent simple negative pressure closed drainage (control group), while 60 patients received combined full irrigation using 0.9% sodium chloride solution (observation group). We compared clinical treatment outcomes, treatment duration, antibiotic usage duration, quality of life scores, Visual Analogue Scale (VAS) scores, changes in serum IL-6 and TNF-alpha levels be-fore and after treatment, and the incidence of complications between the two groups. Additionally, we conducted an analysis of risk factors influencing patient prognosis. Results: The observation group exhibited significantly superior treatment efficacy compared to the control group (P < 0.05). Treatment and antibiotic usage durations were shorter in the observation group (P < 0.05). VAS scores after treatment were significantly lower in the observation group (P < 0.05). Serum inflammatory factors improved significantly in both groups after treatment, with a more substantial improvement observed in the observation group (P < 0.05). Post-treatment quality of life was significantly higher, and the incidence of complications was lower in the observation group (P < 0.05). The choice of treatment method independently influenced patient prognosis (P < 0.05). Conclusion: Combining vacuum sealing drainage with full irrigation is an effective approach for managing oral and maxillofacial space infections. This treatment leads to improved clinical symptoms, reduced inflammatory responses, decreased pain intensity, and enhanced quality of life while maintaining safety.
C1 [Sun, Haoxuan; Zhang, Lili; Li, Xiang; Li, Zhijun; Xin, Jiangbo] Hebei Eye Hosp, Oral & Maxillofacial Surg Ward, 399 Quanbei East St,Xiangdu Dist, Xingtai 054001, Hebei, Peoples R China.
   [Fu, Jun] Hebei Eye Hosp, Med Imaging Dept, 399 Quanbei East St,Xiangdu Dist, Xingtai 054001, Hebei, Peoples R China.
   [Wen, Bo] Hebei Eye Hosp, Med Records & Stat Room,399 Quanbei East St,Xiangd, Xingtai 054001, Hebei, Peoples R China.
   [Zhao, Yi; Tang, Lihua] Hebei Eye Hosp, Hosp Operating Room, 399 Quanbei East St,Xiangdu Dist, Xingtai 054001, Hebei, Peoples R China.
   [Zhao, Yi; Tang, Lihua] Hebei Eye Hosp, Anesthesia Dept, 399 Quanbei East St,Xiangdu Dist, Xingtai 054001, Hebei, Peoples R China.
RP Xin, JB (通讯作者)，Hebei Eye Hosp, Oral & Maxillofacial Surg Ward, 399 Quanbei East St,Xiangdu Dist, Xingtai 054001, Hebei, Peoples R China.
EM xjb66880811@163.com
RI Li, Zhijun/LLK-0729-2024
CR Breckenridge JD, 2011, J PHYSIOTHER, V57, P197, DOI 10.1016/S1836-9553(11)70045-5
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   Chang Bing-ying, 2011, Zhongguo Gu Shang, V24, P952
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   Lins L, 2016, SAGE OPEN MED, V4, DOI [10.1177/2050312116671725, 10.3390/nu15153409, 10.1002/adma.201808200]
   Qian YY, 2022, WORLD J SURG, V46, P2973, DOI 10.1007/s00268-022-06758-9
   Qian YZ, 2021, IRISH J MED SCI, V190, P1045, DOI 10.1007/s11845-020-02431-z
   Qiu Y, 2019, J CRANIO MAXILL SURG, V47, P837, DOI 10.1016/j.jcms.2019.01.031
   Rao DD, 2010, ORAL SURG ORAL MED O, V110, pE7, DOI 10.1016/j.tripleo.2010.04.016
   Tan L, 2018, EXP THER MED, V15, P288, DOI [10.3892/emt.2017.5360, 10.3892/etm.2017.5360]
   Wang J, 2015, MINERVA CHIR, V70, P17
   Xu GK, 2022, J CRANIOFAC SURG, V33, pE696, DOI [10.1097/scs.0000000000008589, 10.1097/SCS.0000000000008589]
   Zhang Gongjie, 2015, Hua Xi Kou Qiang Yi Xue Za Zhi, V33, P393
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   Zhao N, 2020, ORAL DIS, V26, P1586, DOI 10.1111/odi.13421
NR 22
TC 8
Z9 8
U1 0
U2 5
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1943-8141
J9 AM J TRANSL RES
JI Am. J. Transl. Res.
PY 2023
VL 15
IS 11
BP 6605
EP 6612
PG 8
WC Oncology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Research & Experimental Medicine
GA Z8DG8
UT WOS:001114320500016
PM 38074802
DA 2026-07-24
ER

PT J
AU Kreibich, M
   Rylski, B
AF Kreibich, Maximilian
   Rylski, Bartosz
TI Post-sternotomy deep wound infection following aortic surgery: sometimes
   less may be more
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Editorial Material
DE Deep sternal wound infection; Perioperative care (intraoperative care);
   Surgery; Complications; Negative pressure wound therapy; Continuous
   irrigation
ID GRAFT INFECTION; EXPERIENCE; BYPASS
C1 [Kreibich, Maximilian; Rylski, Bartosz] Univ Heart Ctr Freiburg, Dept Cardiovasc Surg, Hugstetter Str 55, D-79106 Freiburg, Germany.
   [Kreibich, Maximilian; Rylski, Bartosz] Univ Freiburg, Fac Med, Freiburg, Germany.
C3 Universitats Herzzentrum Freiburg; University of Freiburg
RP Kreibich, M (通讯作者)，Univ Heart Ctr Freiburg, Dept Cardiovasc Surg, Hugstetter Str 55, D-79106 Freiburg, Germany.
EM maximilian.kreibich@universitaets-herzzentrum.de
RI Rylski, Bartosz/ABF-1642-2021; Kreibich, Maximilian/AAA-7396-2021
OI Rylski, Bartosz/0000-0001-6890-2172; 
CR Aavik A, 2008, EUR J VASC ENDOVASC, V36, P432, DOI 10.1016/j.ejvs.2008.06.034
   Batt M, 2008, EUR J VASC ENDOVASC, V36, P182, DOI 10.1016/j.ejvs.2008.02.013
   Ben Ahmed S, 2018, J VASC SURG, V67, P468, DOI 10.1016/j.jvs.2017.06.088
   Dobrowolski P, 2017, EUR J CARDIO-THORAC, V51, P395, DOI 10.1093/ejcts/ezw280
   FitzGerald SF, 2005, J ANTIMICROB CHEMOTH, V56, P996, DOI 10.1093/jac/dki382
   Fujii T, 2015, ANN THORAC CARDIOVAS, V21, P418, DOI 10.5761/atcs.ra.15-00187
   Ikeno Y, 2019, EUR J CARDIO-THORAC, V55, P975, DOI 10.1093/ejcts/ezy389
   Kreibich M, 2018, ANN THORAC SURG, V106, P498, DOI 10.1016/j.athoracsur.2018.03.012
   KUESTNER LM, 1995, J VASC SURG, V21, P184, DOI 10.1016/S0741-5214(95)70261-X
NR 9
TC 0
Z9 0
U1 0
U2 5
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
EI 1873-734X
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD MAY
PY 2019
VL 55
IS 5
BP 982
EP 983
DI 10.1093/ejcts/ezy462
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA IV2DK
UT WOS:000484087700027
PM 30649253
OA Bronze
DA 2026-07-24
ER

PT J
AU Karapinar, K
   Saydam, Ö
   Metin, M
   Erdogan, S
   Aker, C
   Arik, B
   Citak, N
AF Karapinar, Kemal
   Saydam, Ozkan
   Metin, Muzaffer
   Erdogan, Sertan
   Aker, Cemal
   Arik, Burcu
   Citak, Necati
TI Experience with Vacuum-Assisted Closure in the Management of
   Postpneumonectomy Empyema: An Analysis of Eight Cases
SO THORACIC AND CARDIOVASCULAR SURGEON
LA English
DT Article
DE vacuum-assisted closure; empyema; pneumonectomy
ID NEGATIVE-PRESSURE; WOUND CONTROL; PROMOTE
AB Background The treatment of postpneumonectomic empyema is challenging. The aim of this study was to test the efficacy of vacuum-assisted closure (VAC) in the treatment of patients with open window thoracostomy (OWT).
   Methods Between January 2010 and April 2014, eight patients developed empyema following pneumonectomy for malignant diseases in our department and then underwent an OWT with subsequent VAC therapy; their cases were retrospectively studied. Each session of VAC therapy lasted 72 hours, and therapy was completed after approximately 6 sessions.
   Results OWT in six patients resulted in either decreased size or complete closure after VAC treatment. Five patients had a bronchopleural fistula (BPF), which was closed either with a tracheal stent (three patients), primary suture, or omentoplasty. The BPF in one of these patients closed during VAC therapy. The treatment failed in two patients due to the microfistula becoming obvious in one and persistence of the fistula in the other.
   Conclusion We believe that the use of VAC in the treatment of postpneumonectomy empyema is effective, except for patients with BPF.
C1 [Karapinar, Kemal; Saydam, Ozkan; Metin, Muzaffer; Erdogan, Sertan; Aker, Cemal; Arik, Burcu; Citak, Necati] Yedikule Teaching Hosp Chest Dis & Thorac Surg, Dept Thorac Surg, TR-34020 Istanbul, Turkey.
C3 Istanbul Yedikule Chest Diseases & Thoracic Surgery Training & Research
   Hospital
RP Saydam, Ö (通讯作者)，Yedikule Teaching Hosp Chest Dis & Thorac Surg, Dept Thorac Surg, TR-34020 Istanbul, Turkey.
EM ozkan.saydam@gmail.com
RI Çitak, Necati/AAE-2169-2020; Saydam, Ozkan/ODK-5790-2025; Karapınar,
   Kemal/ISU-7287-2023; Aker, Cemal/AAG-6842-2021
OI Aker, Cemal/0000-0003-1269-7442
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Badreldin AMA, 2013, THORAC CARDIOV SURG, V61, P642, DOI 10.1055/s-0032-1330226
   Banwell P, 1998, BRIT J PLAST SURG, V51, P79, DOI 10.1016/S0007-1226(98)80142-2
   Begum SSS, 2012, ANN THORAC SURG, V94, P1835, DOI 10.1016/j.athoracsur.2012.08.009
   Celik A, 2013, THORAC CARDIOV SURG, V61, P631, DOI 10.1055/s-0032-1331263
   CLAGETT OT, 1963, J THORAC CARDIOV SUR, V45, P141, DOI 10.1016/S0022-5223(19)32877-6
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Gharagozloo Farid, 2006, Thorac Surg Clin, V16, P215, DOI 10.1016/j.thorsurg.2006.05.012
   Koegelenberg CFN, 2008, RESPIRATION, V75, P241, DOI 10.1159/000117172
   Massera F, 2006, ANN THORAC SURG, V82, P288, DOI 10.1016/j.athoracsur.2005.11.046
   Matzi V, 2007, ANN THORAC SURG, V84, P1762, DOI 10.1016/j.athoracsur.2007.05.052
   Miller JI, 2004, GEN THORACIC SURG, P709
   Molnar TF, 2007, EUR J CARDIO-THORAC, V32, P422, DOI 10.1016/j.ejcts.2007.05.028
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   Robinson S., 1915, COLLECTED PAPERS MAY, V7, P618
   Rocco G, 2012, EUR J CARDIO-THORAC, V41, P1069, DOI 10.1093/ejcts/ezr196
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   Varker KA, 2006, ANN THORAC SURG, V81, P723, DOI 10.1016/j.athoracsur.2004.10.040
NR 20
TC 11
Z9 16
U1 0
U2 3
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0171-6425
EI 1439-1902
J9 THORAC CARDIOV SURG
JI Thorac. Cardiovasc. Surg.
PD APR
PY 2016
VL 64
IS 3
BP 258
EP 262
DI 10.1055/s-0034-1390505
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA DI8GA
UT WOS:000373738300014
PM 25602849
DA 2026-07-24
ER

PT J
AU Fujie, M
   Shimizu, M
   Hara, M
   Morita, E
   Kaneko, S
   Imaoka, K
   Kusatake, K
   Ohta, S
AF Fujie, M.
   Shimizu, M.
   Hara, M.
   Morita, E.
   Kaneko, S.
   Imaoka, K.
   Kusatake, K.
   Ohta, S.
TI A CASE OF A MASSIVE ULCER: IMPROVEMENT IN A PATIENT'S SELF-EFFICACY AND
   ACTIVITIES OF DAILY LIVING BY ADMINISTERING NEGATIVE PRESSURE WOUND
   THERAPY AND ENSURING EFFECTIVE CLOSER COMMUNICATION AMONG MEDICAL STAFF
   MEMBERS
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Fujie, M.; Shimizu, M.; Hara, M.; Morita, E.; Kaneko, S.; Imaoka, K.; Kusatake, K.; Ohta, S.] Shimane Univ Hosp, Matsue, Shimane, Japan.
C3 Shimane University
NR 0
TC 0
Z9 0
U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JAN-FEB
PY 2013
VL 21
IS 1
BP A4
EP A4
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 068EQ
UT WOS:000313348500013
DA 2026-07-24
ER

PT J
AU Masters, J
   Cook, J
   Achten, J
   Costa, ML
AF Masters, J.
   Cook, J.
   Achten, J.
   Costa, M. L.
TI A feasibility study of standard dressings versus negative-pressure wound
   therapy in the treatment of adult patients having surgical incisions for
   hip fractures: the WHISH randomized controlled trial (vol 103B, pg 755,
   2021)
SO BONE & JOINT JOURNAL
LA English
DT Correction
RI Achten, Juul/KUD-8515-2024; Cook, Jonathan/D-3648-2015
OI Achten, Juul/0000-0002-8857-5743; Costa, Matthew/0000-0003-3644-1388
CR Masters J, 2021, BONE JOINT J, V103B, P755, DOI 10.1302/0301-620X.103B4.BJJ-2020-1603.R1
NR 1
TC 0
Z9 0
U1 0
U2 2
PU BRITISH EDITORIAL SOC BONE & JOINT SURGERY
PI LONDON
PA 22 BUCKINGHAM STREET, LONDON WC2N 6ET, ENGLAND
SN 2049-4394
J9 BONE JOINT J
JI Bone Joint J.
PD NOV
PY 2021
VL 103B
IS 11
BP 1742
EP 1742
PG 1
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA WS1VO
UT WOS:000714977400005
PM 34719279
DA 2026-07-24
ER

PT J
AU Huang, CC
   Yang, MJ
   Chang, IL
AF Huang, Ching-Cheng
   Yang, Meng-Jen
   Chang, Ing-Lin
TI Preclinical Evaluation and Characteristics of New Cross-Linked Polyvinyl
   Alcohol Extra Permeable Foam Dressings Derived from a combination of
   Super Clean Air foaming and Ultra Precision Machining Processes for
   Negative Pressure Wound Therapy
SO BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
LA English
DT Meeting Abstract
C1 [Huang, Ching-Cheng] Ming Chuan Univ, Dept Biomed Engn, Taoyuan, Taiwan.
   [Huang, Ching-Cheng; Yang, Meng-Jen] PARSD Biomed Mat Res Ctr PBMRC, Changzhou, Jiangsu, Peoples R China.
   [Chang, Ing-Lin] Changhua Christian Hosp, Dept Orthopaed, Changhua, Taiwan.
C3 Ming Chuan University; Changhua Christian Hospital
RI HUANG, CHING-CHENG/AFV-1816-2022
NR 0
TC 0
Z9 0
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-7835
EI 1742-7843
J9 BASIC CLIN PHARMACOL
JI Basic Clin. Pharmacol. Toxicol.
PD APR
PY 2019
VL 124
SU 3
SI SI
MA 016
BP 12
EP 13
PG 2
WC Pharmacology & Pharmacy; Toxicology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pharmacology & Pharmacy; Toxicology
GA HU2HA
UT WOS:000465090800017
DA 2026-07-24
ER

PT J
AU Muresan, M
   Suciu, H
   Marian, D
   Muresan, AV
   Gabor, RM
   Neagoe, RM
   Sala, D
   Denes, M
   Muresan, S
   Melano, MI
   Balmos, IA
AF Muresan, Mircea
   Suciu, Horatiu
   Marian, Dorin
   Muresan, Adrian Vasile
   Gabor, Rozalia Manuela
   Neagoe, Radu Mircea
   Sala, Daniela
   Denes, Marton
   Muresan, Simona
   Melano, Marina Isabella
   Balmos, Ioan Alexandru
TI A single-center prospective study on the efficiency of negative pressure
   wound therapy versus conventional wound therapy in the postoperative
   management of devitalized and infected wounds
SO ANNALI ITALIANI DI CHIRURGIA
LA English
DT Article
DE Negative pressure wound Therapy; Conventional wound therapy; Local
   healing; average cost
ID COST-EFFECTIVENESS
AB <bold>Introduction: </bold>In this study, we aim to present the benefits of using negative pressure wound therapy, particularly with respect to the speed up of recovery time of devitalized and infected post-operative wounds, cost-effectiveness of local healing, pain relief during treatment, and returning to work and resuming normal daily activities at an earlier time. <bold>Materials and methods: </bold>This was a prospective study performed in General Surgery Clinic, between 2016-2018. The study comprised 67 patients divided into two groups: A (29 patients who underwent negative pressure wound therapy) and B (38 patients who underwent conventional wound therapy). <bold>Results: </bold>The average age of patients included in group A was 64.2 +/- 12.3 years and in group B, 63.2 +/- 9.7 years (p=0.440). The wounds were located on the foot, thigh, abdomen, and other areas, and the average length of stay in hospital was 33 +/- 18 days for group A versus 17 +/- 14 days for group B (p=0.042) but with an average local healing time of 12 +/- 5 days in group A versus 44 +/- 17 days in group B (p<0.001). The average cost of hospitalization was higher in group A: 17,868 +/- 9,560 RON (3,834 +/- 2,051 euros) compared to group B: 6,025 +/- 4,137 RON (1,292 +/- 887 euros) (p=0.443) but the average cost of local healing was lower in group A: 5,437 +/- 2,238 RON (1,166 +/- 480 euro) compared to group B: 6,840 +/- 3,520 RON (1,467 +/- 755 euro) (p=0.005). <bold>Conclusions: </bold>The treatment of devitalized and infected post-operative wounds by using negative pressure wound therapy reduces local and complete healing time by approximately 30%, local healing costs by 26%, and allows better pain management during treatment with minimal complications.
C1 [Muresan, Mircea; Marian, Dorin; Neagoe, Radu Mircea; Sala, Daniela; Denes, Marton] Univ Med Pharm Sci & Technol Tirgu Mures, Surg Clin 2, Targu Mures, Romania.
   [Suciu, Horatiu] Univ Med Pharm Sci & Technol Tirgu Mures, Dept Surg, Targu Mures, Romania.
   [Muresan, Adrian Vasile] Univ Med Pharm Sci & Technol Tirgu Mures, Vasc Surg, Targu Mures, Romania.
   [Gabor, Rozalia Manuela] Univ Med Pharm Sci & Technol Tirgu Mures, Fac Econ Law & Adm Sci, Targu Mures, Romania.
   [Muresan, Simona; Melano, Marina Isabella] Univ Med Pharm Sci & Technol Tirgu Mures, Targu Mures, Romania.
   [Balmos, Ioan Alexandru] Univ Med Pharm Sci & Technol Tirgu Mures, Anat Dept, Targu Mures, Romania.
   [Muresan, Simona] Univ Med Pharm Sci & Technol Tirgu Mures, Physiol Dept, Gh Marinescu St 38, Targu Mures, Romania.
C3 George Emil Palade University of Medicine, Pharmacy, Science, &
   Technology of Targu Mures; George Emil Palade University of Medicine,
   Pharmacy, Science, & Technology of Targu Mures; George Emil Palade
   University of Medicine, Pharmacy, Science, & Technology of Targu Mures;
   George Emil Palade University of Medicine, Pharmacy, Science, &
   Technology of Targu Mures; George Emil Palade University of Medicine,
   Pharmacy, Science, & Technology of Targu Mures; George Emil Palade
   University of Medicine, Pharmacy, Science, & Technology of Targu Mures;
   George Emil Palade University of Medicine, Pharmacy, Science, &
   Technology of Targu Mures
RP Muresan, S (通讯作者)，Univ Med Pharm Sci & Technol Tirgu Mures, Physiol Dept, Gh Marinescu St 38, Targu Mures, Romania.
EM dr_mure-mir@yahoo.com
RI GABOR, Manuela Rozalia/AAK-9004-2020; Sala, Daniela
   Tatiana/IAM-2498-2023; Adrian, Muresan/HKM-3966-2023; Balmos, Ioan
   Alexanu/MBH-7042-2025; HORATIU, SUCIU/KFS-9863-2024; Muresan,
   Simona/KIG-8771-2024; Muresan, Mircea/LXV-0408-2024; Neagoe, Radu
   Mircea/AAE-6364-2022
OI GABOR, Manuela Rozalia/0000-0003-1025-869X; Balmos, Ioan
   Alexanu/0000-0002-7134-2660; Muresan, Mircea/0000-0002-5262-8524;
   Neagoe, Radu Mircea/0009-0006-0712-6070
CR [Anonymous], 2010, EQ EXC LIB NHS
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NR 27
TC 1
Z9 1
U1 0
U2 0
PU EDIZIONI LUIGI POZZI
PI ROME
PA VIA PANAMA 68, 00198 ROME, ITALY
SN 0003-469X
EI 2239-253X
J9 ANN ITAL CHIR
JI Ann. Ital. Chir.
PD JUL-AUG
PY 2023
VL 94
IS 4
BP 411
EP 418
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA RD4D1
UT WOS:001225710100001
PM 37794810
DA 2026-07-24
ER

PT J
AU Yin, XL
   Hu, L
   Li, T
   Zou, Y
   Li, HL
AF Yin, Xiao-Ling
   Hu, Ling
   Li, Ting
   Zou, Yi
   Li, Hong-lin
TI A meta-analysis on the efficacy of vacuum sealing drainage combined with
   autologous platelet-rich plasma in the treatment of Grade 2 and Grade 3
   diabetic foot ulcers
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE diabetic foot; meta-analysis; platelet-rich plasma; ulcer; vacuum
   sealing drainage
AB This meta-analysis aims to systemically evaluate the efficacy of vacuum sealing drainage (VSD) combined with autologous platelet-rich plasma (PRP) in the treatment of diabetic foot ulcers (DFU). The China HowNet, China Biomedical Literature, VIP periodical resource integration service platform, Wanfang, Embase, Cochrane Central, and PubMed databases were retrieved using the computer. The retrieval period was up to July 2021. Randomised controlled trials on VSD combined with PRP in the treatment of DFU were collected. Those trials that met the inclusion criteria were included for meta-analysis using RevMan 5.3 software. A total of 13 articles were included. In the trial group, 477 patients with DFU were treated with VSD combined with PRP, while in the control group, 482 patients with DFU were treated with conventional dressings and/or VSD. The meta-analysis showed that, compared with the control group, VSD combined with PRP has significant advantages in shortening healing time (standardised mean difference [SMD] = -0.87, 95% confidence interval [CI]: -1.07 to -0.67, P < .00001), improving ulcer healing rates (odds ratio 4.01, 95% CI: 2.95 similar to 5.46, P < .00001), and reducing hospital stays (mean difference = -15.29, 95% CI: -16.05 to -14.54, P < .00001), but the differences in dressing change times (SMD = -1.27, 95% CI: -2.71 to 0.17, P .08) and hospitalisation expenses (SMD = -0.16, 95% CI: -13.40 to 13.07, P = .98) were not statistically significant. VSD combined with autologous PRP has good curative efficacy in the treatment of DFU and is a better treatment option. However, this treatment is limited in patients with platelet dysfunction, thrombocytopenia, leukaemia, and poor general condition.
C1 [Yin, Xiao-Ling; Hu, Ling; Li, Ting; Zou, Yi] Nanchang Univ, Dept Endocrinol, Hosp Nanchang 1, Affiliated Hosp 3, 128 Xiangshan North Rd, Nanchang 330008, Jiangxi, Peoples R China.
   [Li, Hong-lin] Med Coll Georgia, Dept Biochem, Augusta, GA 30912 USA.
C3 Nanchang University; University System of Georgia; Augusta University
RP Hu, L (通讯作者)，Nanchang Univ, Dept Endocrinol, Hosp Nanchang 1, Affiliated Hosp 3, 128 Xiangshan North Rd, Nanchang 330008, Jiangxi, Peoples R China.
EM drhu_hl1172@163.com
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NR 35
TC 18
Z9 19
U1 1
U2 24
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2023
VL 20
IS 4
BP 1033
EP 1041
DI 10.1111/iwj.13956
EA SEP 2022
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA A7RQ8
UT WOS:000854080200001
PM 36111514
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Li, RG
   Ren, GH
   Tan, XJ
   Yu, B
   Hu, JJ
AF Li, Run-guang
   Ren, Gao-hong
   Tan, Xiong-jin
   Yu, Bin
   Hu, Ji-jie
TI Free flap transplantation combined with skin grafting and vacuum sealing
   drainage for repair of circumferential or sub-circumferential
   soft-tissue wounds of the lower leg
SO MEDICAL SCIENCE MONITOR
LA English
DT Article
DE free flap transplantation; skin grafting; circumferential wounds; vacuum
   sealing drainage (VSD); microsurgical techniques
ID NEGATIVE-PRESSURE THERAPY; ASSISTED CLOSURE; LOWER-EXTREMITY;
   RECONSTRUCTION; MANAGEMENT; COVERAGE; FRACTURES; OUTCOMES; TRAUMA; FLOW
AB Background: This study is aimed at evaluating the operation techniques and clinical significance of free flap transplantation combined with skin grafting and vacuum sealing drainage (VSD) in repairing severe traumatic extensive circumferential or semi-circumferential soft-tissue defects of the lower leg.
   Material/Methods: Thirty patients with severe lower leg injuries were treated by free flap transplantation combined with skin grafting and VSD from January 2008 to June 2011. The size of the wounds ranged from 23 x 8 cm to 44 x 28 cm and all affected more 70% of the low leg circumferential area. Wounds were complicated by exposure, necrosis, or infection of deep tissues. The wounds were first debrided and covered by VSD. When the condition of the wound had improved (5 to 7 days later), free flaps were harvested to reconstruct damaged tissue and skin grafts and VSD was used to cover granulation tissues around the transplanted flap.
   Results: Granulation tissues developed and the area requiring flap cover decreased in all 30 patients after debridement and VSD. In 28 of 30 cases, the transplanted flaps grew well without complication. Peripheral necrosis was observed in only 2 cases, which required a second debridement and skin graft. Ten wound areas covered by grafts were left with scattered peripheral wounds, which healed with the help of 1 more skin graft or dressing change. Morphological appearance and functional recovery were satisfactory in all 30 cases.
   Conclusions: Initial debridement and the temporary VSD cover followed after several days by free flap transplantation combined with skin grafting and VSD protection is a reliable treatment regimen for traumatic large circumferential or sub-circumferential soft tissue wounds of the lower leg with deep tissue exposure.
C1 [Li, Run-guang; Ren, Gao-hong; Yu, Bin; Hu, Ji-jie] Southern Med Univ, Nanfang Hosp, Dept Orthopaed & Traumatol, Guangzhou, Guangdong, Peoples R China.
   [Tan, Xiong-jin] 169th Hosp PLA, Dept Orthoped, Hengyang, Hunan, Peoples R China.
C3 Southern Medical University - China
RP Ren, GH (通讯作者)，Southern Med Univ, Nanfang Hosp, Dept Orthopaed & Traumatol, Guangzhou, Guangdong, Peoples R China.
EM doctor020@163.com
OI Gaohong, Ren/0000-0002-4941-6723; Runguang, Li/0000-0002-4703-7180
FU "Natural Science Foundation of Guangdong Province" in China
   [S2012010009434]; "Special Project on the Integration of Industry,
   Education and Research of Guangdong Province" in China [2012B091100462]
FX This work was supported by the "Natural Science Foundation of Guangdong
   Province" (Approval number S2012010009434) and "Special Project on the
   Integration of Industry, Education and Research of Guangdong Province"
   (Approval number 2012B091100462) in China
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NR 40
TC 35
Z9 56
U1 0
U2 23
PU INT SCIENTIFIC INFORMATION, INC
PI MELVILLE
PA 150 BROADHOLLOW RD, STE 114, MELVILLE, NY 11747 USA
SN 1643-3750
J9 MED SCI MONITOR
JI Med. Sci. Monitor
PD JUN 28
PY 2013
VL 19
BP 510
EP 517
PG 8
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA 174WW
UT WOS:000321188800001
PM 23807087
OA hybrid
DA 2026-07-24
ER

PT J
AU Du, WB
   He, LH
   Wang, LX
   Hu, HH
   Zhou, HT
   Bao, GN
   Chen, RL
   Shen, FX
   Quan, RF
AF Du, Weibin
   He, Lihong
   Wang, Lixiang
   Hu, Huahui
   Zhou, Huateng
   Bao, Guanai
   Chen, Rongliang
   Shen, Fuxiang
   Quan, Renfu
TI Experimental vascular protective shield combined with vacuum sealing
   drainage prevents pressure on exposed vessels and accelerates wound
   repair
SO ANNALS OF PALLIATIVE MEDICINE
LA English
DT Article
DE Vascular protective shield vacuum sealing drainage (VSD); exposed
   vessels; early vascularization; wound repair
ID DIABETIC FOOT ULCERS; THERAPY; SKIN; EXTREMITY
AB Background: The sustained negative pressure created by vacuum sealing drainage (VSD) on exposed vascular wounds can result in blood vessel compression, embolism, or necrosis. 'I'he objective of this research \V a s to explore the ability of an experimental vascular protective shield combined with VSD to protect exposed vessels of the lower limbs and accelerate wound repair.
   Methods: (I) The vascular protective shield was prepared; (II) the material was subjected to acute toxicity and hemolysis tests; (III) and 30 New Zealand rabbits were divided into three groups: the control, VSD-only, and combined shield-VSD groups (with ten rabbits in each group). The wotmd-healing rate, myocardial function, wound histopathology; expression of angiogenesis markers, and exposed vascular compression of these three groups were compared on day 7.
   Results: (I) The internal structure of the material was smooth; and (II) no toxicity or death was observed in mice of any group. 'I'he hemolysis rate in the combined shield-VSD group was very low. (Ill) The combined shield -VS') group showed a higher wound -healing rate, and higher levels of cluster of differentiation 31 (CD31), vascular endothelial growth factor (VEGF), and platelet -derived growth factor (PDGF), than the other groups (P<0.05), along with a better tissue healing rate. (IV) Left ventricular pressure fluctuations in the combined shield-VSD group were smaller than those in the VSD-only group (P<0.05). (V) Blood vessels in the control and combined shield-VSD group were not damaged, but were damaged in the VSD-only group.
   Conclusions: The experimental vascular protective shield exhibited exceptional biosafety. The combination of this shield with VSD reduces influences on systolic and diastolic capacities of myocardium and avoids multiple compressions of exposed vessels, thus contributing to early vascularization of wounds arid wound repair.
C1 [Du, Weibin; He, Lihong; Wang, Lixiang; Hu, Huahui; Zhou, Huateng; Chen, Rongliang; Shen, Fuxiang; Quan, Renfu] Zhejiang Chinese Med Univ, Jiangnan Hosp, Res Inst Orthoped, Hangzhou 312001, Peoples R China.
   [Bao, Guanai] Univ Chinese Acad Sci, Zhejiang Canc Hosp, Canc Hosp, Dept Rehabil, Hangzhou, Peoples R China.
   [Bao, Guanai] Chinese Acad Sci, Inst Canc & Basic Med IBMC, Hangzhou, Peoples R China.
C3 Zhejiang Chinese Medical University; Zhejiang Cancer Hospital; Chinese
   Academy of Sciences; University of Chinese Academy of Sciences, CAS;
   Chinese Academy of Sciences
RP Du, WB; Quan, RF (通讯作者)，Zhejiang Chinese Med Univ, Jiangnan Hosp, Res Inst Orthoped, Hangzhou 312001, Peoples R China.
EM dwbbdm@163.com; quanrenfu@126.com
FU National Natural Science Foundation of China [81904053]; Plan Guide
   Project of Hangzhou Technology Department [20171226Y93, 20171226Y96];
   Plan Project of Hangzhou Health Science and Technology Department
   [2018B030]; Great Technology Capture Project of Hangzhou Xiaoshan
   District [2017208, 2017214]
FX This work was supported by National Natural Science Foundation of China
   (No. 81904053), the Plan Guide Project of Hangzhou Technology Department
   (No. 20171226Y93, 20171226Y96), the Plan Project of Hangzhou Health
   Science and Technology Department (No. 2018B030), and the Great
   Technology Capture Project of Hangzhou Xiaoshan District (No. 2017208,
   2017214).
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NR 30
TC 3
Z9 3
U1 1
U2 11
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2224-5820
EI 2224-5839
J9 ANN PALLIAT MED
JI Ann. Pallliat. Med.
PD SEP
PY 2020
VL 9
IS 5
BP 3059
EP 3069
DI 10.21037/apm-20-625
PG 11
WC Health Care Sciences & Services
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services
GA NY8YP
UT WOS:000576670500071
PM 32819134
OA gold
DA 2026-07-24
ER

PT J
AU Schintler, MV
   Prandl, EC
AF Schintler, M. V.
   Prandl, E. -C.
TI Vacuum-assisted closure - what is evidence based?
SO EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA
LA English
DT Article
DE vacuum-assisted closure; conventional wound treatment; randomised
   clinical trials; evidence-based medicine
ID PRESSURE WOUND THERAPY; SUBATMOSPHERIC PRESSURE; NEGATIVE-PRESSURE;
   BASIC RESEARCH; FOUNDATION; INJURY; STATE
AB Background: VAC - vacuum-assisted closure, synonymous with TNP ( topical negative pressure) or VT ( Vacuum therapy) is a mode of therapy used to encourage wound healing. It is used both as primary treatment of chronic and complex wounds and as an adjunct for temporary closure and wound bed preparation preceding surgical procedures such as skin grafts and flap surgery. The device has come into wide and successful use although the physiological basis of its effect is not yet understood and few evidence-based data are available.
   Methods: A meta-analysis was made of peer-reviewed publications (PubMed-Medline) chosen on the basis of inclusion of the terms, randomised clinical trials, vacuum-assisted closure, and topical negative pressure.
   Results: Scientific data were evaluated from experimental animal studies, randomised clinical trials, observations of clinical applications and case reports on all known effects of VAC therapy. Systematic analysis of the data shows efficacy concerning induction of wound-healing mechanisms, especially in the early stage. Increased perfusion can be considered proven. Data analysis shows positive efficacy for the treatment of infection.
   Conclusions: Although this therapy appears effective, its superiority to conventional techniques has not been demonstrated. Because its mechanisms of action remain unclear, and as there is a gap between evidence-based data and the excellent clinical results, further prospective randomised blinded studies are needed. Even so, we conclude that VT ( vacuum therapy), used when indicated especially by experienced surgeons, is an excellent tool to support wound healing.
C1 [Schintler, M. V.; Prandl, E. -C.] Med Univ Graz, Dept Surg, Div Plast Surg, A-8036 Graz, Austria.
C3 Medical University of Graz
RP Schintler, MV (通讯作者)，Med Univ Graz, Dept Surg, Div Plast Surg, Auenbruggerpl 29, A-8036 Graz, Austria.
EM michael.schintler@meduni-graz.at
CR ADAMS TST, 2004, TOPICAL NEGATIVE PRE
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NR 45
TC 7
Z9 7
U1 0
U2 2
PU SPRINGER WIEN
PI WIEN
PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 WIEN, AUSTRIA
SN 1682-8631
J9 EUR SURG
JI Eur. Surg.
PD FEB
PY 2008
VL 40
IS 1
BP 11
EP 18
DI 10.1007/s10353-008-0381-5
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 315GA
UT WOS:000256865000003
DA 2026-07-24
ER

PT J
AU Huang, TH
   Huang, HP
AF Huang, Taihua
   Huang, Haiping
TI Application effect of vacuum sealing drainage combined with nano-silver
   dressings in the treatment of non-healing wounds after surgery for open
   limb fractures
SO JOURNAL OF ORTHOPAEDIC SCIENCE
LA English
DT Article
DE Vacuum sealing drainage; Nano-silver dressings; Fracture; Non-healing
   wound; Inflammatory factors; Scar proliferation
ID EFFICACY
AB Background Non-healing wounds after open limb fracture surgery pose clinical challenges, requiring effective management; vacuum sealing drainage (VSD) promotes healing by removing exudate and stimulating granulation, while nano-silver dressings provide antimicrobial protection to reduce infection risk. We aimed to probe the application effect of VSD combined with nano-silver dressings in the treatment of non-healing wounds after surgery for Gustilo type III open limb fractures. Methods A total of 60 patients with non-healing wounds after surgery for Gustilo type III open limb fractures were randomly divided into two groups, with 30 cases in each group. The control group received conventional therapy, and the study group received VSD combined with nano-silver dressings. Before treatment and after 7 days of treatment, inflammatory cytokines (C-reactive protein (CRP) and procalcitonin (PCT)) in serum and growth factors (transforming growth factor beta1 (TGF-beta 1) and vascular endothelial growth factor (VEGF)) in wound exudate were measured using enzyme-linked immunosorbent assay. The pain level of the patients was measured by the Visual Analogue Scale (VAS). Patients' skin quality was assessed by the Vancouver Scar Scale (VSS), and the efficacy of trauma treatment was observed in both groups. Results After 7-day treatment, the study group performed lower levels of CRP and PCT, higher levels of TGF-beta 1 and VEGF, lower VAS scores and VSS scores, and better overall treatment rate compared to the control group (all P < 0.05). Conclusion VSD combined with nano-silver dressings has good therapeutic efficacy in non-healing wounds after surgery for open limb fractures and can inhibit inflammatory response and improve skin quality. (c) 2025 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
C1 [Huang, Taihua; Huang, Haiping] Mianyang Orthoped Hosp, Dept Knee Joint, 158 South Sect Changhong Ave, Mianyang 621000, Sichuan, Peoples R China.
RP Huang, TH (通讯作者)，Mianyang Orthoped Hosp, Dept Knee Joint, 158 South Sect Changhong Ave, Mianyang 621000, Sichuan, Peoples R China.
EM Huangtaihua2868@163.com
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NR 27
TC 0
Z9 0
U1 3
U2 3
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 0949-2658
EI 1436-2023
J9 J ORTHOP SCI
JI J. Orthop. Sci.
PD JAN
PY 2026
VL 31
IS 1
BP 207
EP 212
DI 10.1016/j.jos.2025.05.012
EA JAN 2026
PG 6
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA CG6YN
UT WOS:001665354700001
PM 40675903
DA 2026-07-24
ER

PT J
AU Hu, N
   Wu, XH
   Liu, R
   Yang, SH
   Huang, W
   Jiang, DM
   Wu, Q
   Xia, T
   Shao, ZW
   Ye, ZW
AF Hu, Ning
   Wu, Xing-huo
   Liu, Rong
   Yang, Shu-hua
   Huang, Wei
   Jiang, Dian-ming
   Wu, Qiang
   Xia, Tian
   Shao, Zeng-wu
   Ye, Zhe-wei
TI Novel application of vacuum sealing drainage with continuous irrigation
   of potassium permanganate for managing infective wounds of gas gangrene
SO JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL
   SCIENCES
LA English
DT Article
DE vacuum sealing drainage; potassium permanganate; irrigation; gas
   gangrene; trauma
ID OF-THE-LITERATURE; NEGATIVE-PRESSURE; ASSISTED CLOSURE;
   HYPERBARIC-OXYGEN; TISSUE DEFECTS; THERAPY; MANAGEMENT
AB Traumatic gas gangrene is a fatal infection mainly caused by Clostridium perfringens. It is a challenge to manage gas gangrene in open wounds and control infection after debridement or amputation. The aim of the present study was to use vacuum sealing drainage (VSD) with continuous irrigation of potassium permanganate to manage infective wounds of gas gangrene and observe its clinical efficacy. A total of 48 patients with open traumatic gas gangrene infection were included in this study. Amputations were done for 27 patients, and limb salvage procedures were performed for the others. After amputation or aggressive debridement, the VSD system, including polyvinyl alcohol (PVA) foam dressing and polyurethane (PU) film, with continuous irrigation of 1:5000 potassium permanganate solutions, was applied to the wounds. During the follow-up, all the patients healed without recurrence within 8-18 months. There were four complications. Cardiac arrest during amputation surgery occurred in one patient who suffered from severe septic shock. Emergent resuscitation was performed and the patient returned to stable condition. One patient suffered from mixed infection of Staphylococcal aureus, and a second-stage debridement was performed. One patient suffered from severe pain of the limb after the debridement. Exploratory operation was done and the possible reason was trauma of a local peripheral nerve. Three cases of crush syndrome had dialysis treatment for concomitant renal failure. In conclusion, VSD can convert open wound to closed wound, and evacuate necrotic tissues. Furthermore, potassium permanganate solutions help eliminate anaerobic microenvironment and achieve good therapeutic effect on gas gangrene and mixed infection. VSD with continuous irrigation of potassium permanganate is a novel, simple and feasible alternative for severe traumatic open wounds with gas gangrene infection.
C1 [Hu, Ning; Jiang, Dian-ming] Chongqing Med Univ, Affiliated Hosp 1, Inst Orthopaed Res & Educ, Dept Orthopaed Surg, Chongqing 400016, Peoples R China.
   [Wu, Xing-huo; Yang, Shu-hua; Huang, Wei; Wu, Qiang; Xia, Tian; Shao, Zeng-wu; Ye, Zhe-wei] Huazhong Univ Sci & Technol, Tongji Med Coll, Union Hosp, Dept Orthopaed Surg, Wuhan 430022, Peoples R China.
   [Liu, Rong] Wuhan Univ Sci & Technol, Wuhan Puren Hosp, Dept Orthopaed Surg, Wuhan 430080, Peoples R China.
C3 Chongqing Medical University; Huazhong University of Science &
   Technology; Wuhan University of Science & Technology
RP Ye, ZW (通讯作者)，Huazhong Univ Sci & Technol, Tongji Med Coll, Union Hosp, Dept Orthopaed Surg, Wuhan 430022, Peoples R China.
EM ninghu@126.com; wuxinghuo@163.com; 56138779@qq.com
RI Shao, Zengwu/E-9301-2018; Ye, Zhewei/OMM-6832-2025
OI hu, ning/0000-0001-9933-5924; liu, yifei/0009-0002-3294-1668; Ye,
   Zhewei/0000-0002-2730-9820; Liu, Rong/0000-0002-0575-3293
FU National Natural Science Foundation of China [81201393]
FX This study was supported by a grant from the National Natural Science
   Foundation of China (No. 81201393).
CR Aggelidakis J, 2011, WORLD J EMERG SURG, V6, DOI 10.1186/1749-7922-6-28
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NR 30
TC 17
Z9 18
U1 0
U2 19
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1672-0733
EI 1993-1352
J9 J HUAZHONG U SCI-MED
JI J. Huazhong Univ. Sci. Tech.-Med.
PD AUG
PY 2015
VL 35
IS 4
BP 563
EP 568
DI 10.1007/s11596-015-1471-9
PG 6
WC Biochemistry & Molecular Biology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biochemistry & Molecular Biology
GA CN9JC
UT WOS:000358762100017
PM 26223928
DA 2026-07-24
ER

PT J
AU Ozer, MT
   Sinan, H
   Zeybek, N
   Peker, Y
AF Ozer, M. Tahir
   Sinan, Huseyin
   Zeybek, Nazif
   Peker, Yusuf
TI A simple novel technique for enteroatmospheric fistulae: silicone
   fistula plug
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE EAF; Enteroatmospheric fistula; Negative pressure wound therapy; NPWT;
   Open abdomen
ID OPEN ABDOMEN; MANAGEMENT
AB Enteroatmospheric fistulae (EAFs), a rare condition that develops in patients treated with an open abdomen, present serious problems for the surgeon. There are no fixed algorithms for treatment of EAF, and treatment options are determined based on the experience of the surgeon and status of the patient. We developed a 'suspended silicone fistula plug' for treating a patient who developed an EAF after undergoing multiple operations in a short period of time. Used in conjunction with negative pressure wound therapy, application of this novel therapy resulted in EAF closure and patient discharge.
C1 [Ozer, M. Tahir; Sinan, Huseyin; Zeybek, Nazif; Peker, Yusuf] Gulhane Mil Med Acad, Dept Gen Surg, Ankara, Turkey.
C3 Gulhane Training & Research Hospital
RP Ozer, MT (通讯作者)，Gulhane Mil Med Acad, Dept Gastrointestinal Surg, Ankara, Turkey.
EM mtahirozer@gmail.com
OI Zeybek, Nazif/0000-0001-5033-834X
CR D'Hondt M, 2011, AM J SURG, V202, pE20, DOI 10.1016/j.amjsurg.2010.06.025
   Di Saverio S, 2011, J TRAUMA, V71, P760, DOI 10.1097/TA.0b013e318216e340
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   Prichayudh S, 2011, SURG TODAY, V41, P72, DOI 10.1007/s00595-009-4202-7
NR 7
TC 14
Z9 17
U1 0
U2 6
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2014
VL 11
SU 1
SI SI
BP 22
EP 24
DI 10.1111/iwj.12308
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA AJ3MO
UT WOS:000337570900007
PM 24851733
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Hadawi, H
   Middleton, B
AF Hadawi, H.
   Middleton, B.
TI Negative Pressure Wound therapy (NPWT-PICO): reducing risk of surgical
   site infections (SSIs) postlower segment caesarean section (LSCS) in
   women with high BMI women? A study performed at Western Sussex Hospitals
   Foundation Trust (WSHFT)
SO BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
LA English
DT Meeting Abstract
C1 [Hadawi, H.] Royal Surrey Cty Hosp, Guildford, Surrey, England.
   [Middleton, B.] St Richards Hosp, Chichester, England.
C3 Royal Surrey County Hospital
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1470-0328
EI 1471-0528
J9 BJOG-INT J OBSTET GY
JI BJOG
PD MAY
PY 2021
VL 128
SU 1
SI SI
MA 372
BP 80
EP 80
PG 1
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA SG3IS
UT WOS:000653336100197
DA 2026-07-24
ER

PT J
AU Yuan, KZ
   Zhao, B
   Cooper, T
   Jin, ZY
   Zhou, XJ
   Chen, XL
   Li, ZJ
   Gao, WY
   Yan, HD
AF Yuan, Kaizong
   Zhao, Bin
   Cooper, Tokai
   Jin, Zeyuan
   Zhou, Xijie
   Chen, Xinglong
   Li, Zhijie
   Gao, Weiyang
   Yan, Hede
TI The management of degloving injuries of the limb with full thickness
   skin grafting using vacuum sealing drainage or traditional compression
   dressing: A comparative cohort study
SO JOURNAL OF ORTHOPAEDIC SCIENCE
LA English
DT Article
ID CIRCUMFERENTIALLY AVULSED SKIN; TECHNICAL REFINEMENT; ASSISTED CLOSURE;
   THERAPY; EXTREMITIES; FRACTURES; DEEP
AB Background: Degloving injuries of the limb are severe and frequently underrated. Few researches are available comparing the results of reattachment of the degloved skin grafts with the vacuum sealing drainage technique and the traditional compression dressing method. In this study, we aimed to compare the treatment outcomes of these two approaches.
   Methods: Eighty-three consecutive patients were treated for degloving injury of the limb. Based on the treatment approach, the patients were divided into vacuum sealing drainage group (VSD group, n = 55) and traditional compression dressing group (TCD group, n = 28). After reattachment, the degloved skin was secured with stitches and compressed with VSD or TCD. The outcomes were mainly assessed based on the percentage of skin graft take.
   Result: In VSD group, there were excellent results in 18, fair in 9 and poor in 28, respectively; In TCD group, there were excellent results in 11, fair in 10 and poor in 7, respectively. Statistically, no significant difference was found between two groups in terms of the category of excellent results. However, significant higher incidence of poor results with necrotic areas exceeding 50% was observed in the VSD group than that in the TCD group. In addition, although the duration of hospitalization in the VSD group was shorter than that in the TCD group, the medical supply costs and total costs were much higher than that of the TCD group.
   Conclusion: VSD and TCD are equally effective in the management of degloving injuries of the limb; however, VSD technique may potentially have a higher risk of poor results with increased hospital charges. The traditional approach still has its merits in clinical practice, especially in rural hospitals when VSD is not available or unaffordable. (C) 2019 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
C1 Wenzhou Med Univ, Affiliated Hosp 2, Dept Orthopaed Surg, Wenzhou 325000, Peoples R China.
   Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou 325000, Peoples R China.
C3 Wenzhou Medical University; Wenzhou Medical University
RP Yan, HD (通讯作者)，109 XueYuan West Rd, Wenzhou, Zhejiang, Peoples R China.
EM 513740828@qq.com; 969545367@qq.com; coopertokaib@yahoo.com;
   zjwzjzy@yeah.net; 493565783@qq.com; drchenxinglong@126.com;
   lzhjwh@126.com; 996020299@qq.com; yanhede@hotmail.com
RI Chen, Xinglong/ACE-2741-2022
CR Arnez ZM, 2010, J PLAST RECONSTR AES, V63, P1865, DOI 10.1016/j.bjps.2009.11.029
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NR 32
TC 11
Z9 16
U1 0
U2 2
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 0949-2658
EI 1436-2023
J9 J ORTHOP SCI
JI J. Orthop. Sci.
PD SEP
PY 2019
VL 24
IS 5
BP 881
EP 887
DI 10.1016/j.jos.2019.01.002
PG 7
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA IW2XN
UT WOS:000484844800021
PM 30709789
DA 2026-07-24
ER

PT J
AU Wei, S
   Wang, W
   Li, L
   Meng, HY
   Feng, CZ
   Dong, YY
   Fang, XC
   Dong, QQ
   Jiang, W
   Xin, HL
   Li, ZZ
   Wang, X
AF Wei, Shuai
   Wang, Wei
   Li, Li
   Meng, Hao-Ye
   Feng, Chun-Zhen
   Dong, Yu-Ying
   Fang, Xi-Chi
   Dong, Qi-Qiang
   Jiang, Wen
   Xin, Hai-Li
   Li, Zhan-Zhen
   Wang, Xin
TI Recombinant human epidermal growth factor combined with vacuum sealing
   drainage for wound healing in Bama pigs
SO MILITARY MEDICAL RESEARCH
LA English
DT Article
DE Vacuum sealing drainage; Epidermal growth factor; Skin wound healing;
   Full-thickness skin defect
AB Background Vacuum sealing drainage (VSD) and epidermal growth factor (EGF) both play an important role in the treatment of wounds. This study aims to explore the effects of the combination of VSD and EGF on wound healing and the optimal concentration and time of EGF. Methods We tested the proliferation and migration capacity of HaCaT and L929 cells at different EGF concentrations (0, 1, 5, 10, and 100 ng/ml) and different EGF action times (2, 10, and 30 min). A full-thickness skin defect model was established using male, 30-week-old Bama pigs. The experiment included groups as follows: routine dressing change after covering with sterile auxiliary material (Control), continuous negative pressure drainage of the wound (VSD), continuous negative pressure drainage of the wound and injection of EGF 10 min followed by removal by continuous lavage (V + E 10 min), and continuous negative pressure drainage of the wound and injection of EGF 30 min followed by removal by continuous lavage (V + E 30 min). The wound healing rate, histological repair effect and collagen deposition were compared among the four groups. Results An EGF concentration of 10 ng/ml and an action time of 10 min had optimal effects on the proliferation and migration capacities of HaCaT and L929 cells. The drug dispersion effect was better than drug infusion after bolus injection effect, and the contact surface was wider. Compared with other groups, the V + E 10 min group promoted wound healing to the greatest extent and obtained the best histological score. Conclusions A recombinant human epidermal growth factor (rhEGF) concentration of 10 ng/ml can promote the proliferation and migration of epithelial cells and fibroblasts to the greatest extent in vitro. VSD combined with rhEGF kept in place for 10 min and then washed, can promote wound healing better than the other treatments in vivo.
C1 [Wei, Shuai; Meng, Hao-Ye; Wang, Xin] Chinese Peoples Liberat Army Gen Hosp, Beijing Key Lab Regenerat Med Orthopaed, Inst Orthopaed, Beijing 100583, Peoples R China.
   [Wei, Shuai; Li, Zhan-Zhen; Wang, Xin] Zhoushan Dinghai Guanghua Hosp, Zhoushan 316000, Peoples R China.
   [Wei, Shuai] Tianjin Univ, Tianjin Hosp, Tianjin 300211, Peoples R China.
   [Wang, Wei] Chinese Peoples Liberat Army Gen Hosp, Med Ctr 2, Geriatr Neurol Dept, Beijing 100853, Peoples R China.
   [Wang, Wei] Chinese Peoples Liberat Army Gen Hosp, Natl Clin Res Ctr Geriatr Dis, Beijing 100853, Peoples R China.
   [Li, Li] Tradit Chinese Med Hosp Xinjiang Uygur Autonomous, Dept Orthoped, Urumqi 830000, Peoples R China.
   [Feng, Chun-Zhen] Chinese Peoples Liberat Army Gen Hosp, Dept Stomatol, Beijing 100853, Peoples R China.
   [Dong, Yu-Ying] Taiyuan Iron & Steel Ltd Co, Gen Hosp, Dept Plast Surg, Taiyuan 030009, Peoples R China.
   [Fang, Xi-Chi] Shenzhen Peoples Hosp, Hand Microsurg Dept, Shenzhen 518020, Peoples R China.
   [Dong, Qi-Qiang] Zhengzhou Renji Hosp, Surg Dept 3, Zhengzhou 450000, Peoples R China.
   [Jiang, Wen] Shihezi Univ, Med Coll, Affiliated Hosp 1, Dept Orthoped, Xinjiang 832000, Uygur Autonomou, Peoples R China.
   [Xin, Hai-Li] Chinese Peoples Liberat Army Gen Hosp, Pharm Dept, Beijing 100853, Peoples R China.
C3 Chinese People's Liberation Army General Hospital; Tianjin University;
   Chinese People's Liberation Army General Hospital; Chinese People's
   Liberation Army General Hospital; Chinese People's Liberation Army
   General Hospital; Taiyuan Iron & Steel Group; Jinan University; Shihezi
   University; Chinese People's Liberation Army General Hospital
RP Wang, X (通讯作者)，Chinese Peoples Liberat Army Gen Hosp, Beijing Key Lab Regenerat Med Orthopaed, Inst Orthopaed, Beijing 100583, Peoples R China.; Li, ZZ; Wang, X (通讯作者)，Zhoushan Dinghai Guanghua Hosp, Zhoushan 316000, Peoples R China.
EM lizz2688@163.com; wangx126@126.com
RI wei, shuai/AAD-7254-2021; WANG, Xinxin/MVW-1205-2025
OI wei, shuai/0000-0002-2435-815X; 
FU National Natural Science Foundation of China [81972047, 81603008,
   81572148]
FX This study was supported in part by the National Natural Science
   Foundation of China (81972047, 81603008, 81572148).
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NR 48
TC 41
Z9 47
U1 3
U2 37
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 2095-7467
EI 2054-9369
J9 MILITARY MED RES
JI MILITARY MED. RES.
PD MAR 9
PY 2021
VL 8
IS 1
AR 18
DI 10.1186/s40779-021-00308-5
PG 14
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA QT6BM
UT WOS:000626671200001
PM 33685528
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Chen, X
   Mei, ZJ
   Shao, XS
AF Chen, Xiong
   Mei, Zujun
   Shao, Xianshu
TI The combination of a local injection of insulin and vacuum sealing
   drainage in patients with diabetic foot disease
SO INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
LA English
DT Article
DE Insulin; vacuum sealing drainage; diabetic foot disease; granulation
   tissue; therapeutic effect
ID PLATELET-RICH PLASMA; CARE
AB Objective: To investigate the effect of a local injection of insulin in combination with vacuum sealing drainage (VSD) in patients with diabetic foot disease. Methods: A total of 98 patients with diabetic foot disease were randomly assigned to an observation group or a control group, with 49 patients in each group. The patients in the control group were assigned to VSD, and those in the observation group were given a local injection of insulin in addition to the treatment received by those in the control group. The clinical therapeutic effects of the regimens were compared between the two groups. The degree of granulation tissue regeneration was observed in both groups. The levels of insulin-like growth factor 1 (IGF1), serum inflammatory cytokines, oxidative stress, and the activities of lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) in the granulation tissues were measured and compared between the two groups. Results: After treatment, the effective rates and the degree of granulation tissue regeneration were significantly higher in the observation group than they were in the control group (both P<0.05); the levels of IGF1, vascular endothelial growth factor (VEGF), total antioxidant capacity (TAC) of serum, catalase (CAT), and SDH were significantly elevated in both groups (all P<0.001), with significantly higher levels of the markers in the observation group (all P<0.001); in contrast, the levels of interleukin 6 (IL-6), malondialdehyde (MDA), and LDH in both groups were reduced considerably (all P<0.001), with substantially lower levels in the observation group (all P<0.001). Conclusion: Conventional VSD and a concomitant local injection of insulin improved the clinical manifestations, reduced the inflammatory reaction, and promoted the regeneration of granulation tissues in patients with diabetic foot disease. Thus, it is worthy of generalization in clinical practice.
C1 [Chen, Xiong] Jingzhou Cent Hosp, Dept Emergency Surg, Jingzhou, Hubei, Peoples R China.
   [Mei, Zujun] Jingzhou Cent Hosp, Dept Emergency, Jingzhou, Hubei, Peoples R China.
   [Shao, Xianshu] Jianghan Univ, Hosp Wuhan 6, Affiliated Hosp, Dept Western Med, 168 Hong Kong Rd, Wuhan 430015, Hubei, Peoples R China.
C3 Jianghan University
RP Shao, XS (通讯作者)，Jianghan Univ, Hosp Wuhan 6, Affiliated Hosp, Dept Western Med, 168 Hong Kong Rd, Wuhan 430015, Hubei, Peoples R China.
EM sha-oxianshu7sx6s@163.com
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NR 21
TC 0
Z9 0
U1 0
U2 2
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1940-5901
J9 INT J CLIN EXP MED
JI Int. J. Clin. Exp. Med.
PY 2020
VL 13
IS 3
BP 1905
EP 1912
PG 8
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA KY7GN
UT WOS:000522742100071
DA 2026-07-24
ER

PT J
AU Egin, S
   Gökçek, B
   Yesiltas, M
   Hot, S
   Kamali, S
   Isil, RG
   Tok, H
   Karahan, SR
AF Egin, Seracettin
   Gokcek, Berk
   Yesiltas, Metin
   Hot, Semih
   Kamali, Sedat
   Isil, Riza Gurhan
   Tok, Hasan
   Karahan, Servet Rustu
TI THE FACTORS AFFECTING SURVIVAL IN OPEN ABDOMEN DUE TO SURGICAL ABDOMINAL
   SEPSIS
SO ACTA MEDICA MEDITERRANEA
LA English
DT Article
DE Abdominal sepsis; Open abdomen; Vacuum-assisted closure; Negative
   pressure therapy
ID COMPARTMENT SYNDROME; MANAGEMENT; GUIDELINES; SOCIETY; CLOSURE
AB Introduction: In the literature, there are studies comparing open abdomen technique and primary closure technique in terms of survival and other results in patients with surgical abdominal sepsis. There are no studies investigating the factors affecting survival in patients treated with open abdominal technique alone. These factors should be investigated retrospectively in open abdomen patients. We aimed to investigate the factors of survival in patients with severe intraabdominal sepsis treated with vacuum-assisted closure systems for open abdomen. We hypothesized that use of open abdomen with vacuum-assisted closure systems was reduced mortality in patients with severe intraabdominal sepsis.
   Materials and methods: We retrospectively reviewed 40 open abdomen patients performed vacuum-assisted closure for severe intraabdominal sepsis. Alive and mortal groups were evaluated in terms of age, gender, body mass index, etiology of surgical abdominal sepsis, Apache II score, Mannheim peritonitis index score, Bjorck classification, fascia score, abdominal defect size, stoma and fistula presence, and vacuum-assisted closure treatment duration. It was evaluated whether any of these parameters was effective on survival.
   Results: Mean age and body mass index were significantly elevated in the mortal group compared with the alive group. A significant difference with regard to Bjorck classification was detected between the alive and mortal groups. In Bjorck 1 and 2, mortality rates were 36.8% and 31.3%, respectively, while in Bjorck 4, mortality was 100%. The presence and ope of fistula were statistically significant for mortality. None of the other parameters were statistically significant for mortality.
   Discussion: The studies of the last twelve years showed that the open abdomen technique with the temporary abdominal wall closure using negative pressure dressing methods gave positive results. The 42.5% mortality rate in our study is much lower than the mortality rate for abdominal sepsis patients in the literature. Our study indicated that the management of open abdomen and negative pressure therapy was possible to increase the survival in patients with surgical abdominal sepsis.
C1 [Egin, Seracettin; Gokcek, Berk; Yesiltas, Metin; Hot, Semih; Kamali, Sedat; Isil, Riza Gurhan; Tok, Hasan; Karahan, Servet Rustu] Saglik Bilimleri Univ, Okmeydani Educ & Res Hosp, Darulaceze Cad 25, TR-34384 Istanbul, Turkey.
C3 Istanbul Okmeydani Training & Research Hospital; University of Health
   Sciences Turkey
RP Egin, S (通讯作者)，Saglik Bilimleri Univ, Okmeydani Educ & Res Hosp, Darulaceze Cad 25, TR-34384 Istanbul, Turkey.
EM seracettin_egin@hotmail.com
RI /ADG-3811-2022; /R-3639-2018; Gökçek, Berk/X-9343-2018; Eğin,
   Seracettin/GQZ-0908-2022; Kamalı, Sedat/GRS-4734-2022
OI Gökçek, Berk/0000-0001-9989-4152; 
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NR 23
TC 0
Z9 0
U1 0
U2 0
PU CARBONE EDITORE
PI PALERMO
PA VIA QUINTINO SELLA, 68, PALERMO, 90139, ITALY
SN 0393-6384
EI 2283-9720
J9 ACTA MEDICA MEDITERR
JI Acta Medica Mediterr.
PY 2018
VL 34
IS 6
BP 2031
EP 2036
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GX5TR
UT WOS:000447814400068
DA 2026-07-24
ER

PT J
AU Schecter, WP
   Ivatury, RR
   Rotondo, MF
   Hirshberg, A
AF Schecter, William P.
   Ivatury, Rao R.
   Rotondo, Michael F.
   Hirshberg, Asher
TI Open abdomen after trauma and abdominal sepsis: A strategy for
   management
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Article; Proceedings Paper
CT 91st Annual Clinical Congress of the American-College-of-Surgeons
CY OCT 16-20, 2005
CL San Francisco, CA
SP Amer Coll Surg
ID VACUUM-ASSISTED CLOSURE; PLANNED MULTIPLE LAPAROTOMIES; COMPARTMENT
   SYNDROME; ENTEROCUTANEOUS FISTULA; DAMAGE CONTROL; INTRAABDOMINAL
   HYPERTENSION; WALL RECONSTRUCTION; DIFFUSE PERITONITIS; MESENTERIC
   ISCHEMIA; PRIMARY ANASTOMOSIS
C1 Univ Calif San Francisco, Dept Surg, San Francisco, CA 94143 USA.
   Virginia Commonwealth Univ, Richmond, VA USA.
   E Carolina Univ, Sch Med, Greenville, NC USA.
   Baylor Coll Med, Houston, TX 77030 USA.
C3 University of California System; University of California San Francisco;
   Virginia Commonwealth University; University of North Carolina; East
   Carolina University; Baylor College of Medicine
RP Schecter, WP (通讯作者)，San Francisco Gen Hosp, Dept Surg, 1001 Potrero Ave,Ward 3A, San Francisco, CA 94110 USA.
RI Ivatury, Rao/H-2922-2019
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NR 57
TC 115
Z9 124
U1 0
U2 7
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1072-7515
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD SEP
PY 2006
VL 203
IS 3
BP 390
EP 396
DI 10.1016/j.jamcollsurg.2006.06.001
PG 7
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 081CT
UT WOS:000240295500015
PM 16931311
DA 2026-07-24
ER

PT J
AU Sjödin, LW
   Bosanquet, DC
AF Sjodin, Lina Walther
   Bosanquet, David C.
TI What Does NPWT Mean in the Context of Major Lower Limb Amputation: Not
   Proven with Tangible Evidence or Noteworthy Prevention of Wound
   Troubles?
SO EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
LA English
DT Editorial Material
DE Major lower extremity amputation; Negative pressure wound therapy;
   Surgical site infection
C1 [Sjodin, Lina Walther] Karolinska Inst, Dept Clin Sci & Educ, Sodersjukhuset, Stockholm, Sweden.
   [Sjodin, Lina Walther] Soder Sjukhuset, Dept Orthopaed, S-11883 Stockholm, Sweden.
   [Bosanquet, David C.] South East Wales Vasc Network, Cardiff, Wales.
   [Bosanquet, David C.] Royal Gwent Hosp, Gwent Vasc Inst, Newport, Wales.
C3 Karolinska Institutet; Sodersjukhuset Hospital; Sodersjukhuset Hospital;
   Royal Gwent Hospital
RP Sjödin, LW (通讯作者)，Soder Sjukhuset, Dept Orthopaed, S-11883 Stockholm, Sweden.
EM lina.walther.sjodin@ki.se
OI Bosanquet, David/0000-0003-2304-0489
CR Al-Saadi N, 2024, INT WOUND J, V21, DOI [10.1111/iwj.14946, 10.1111/iwj.14946]
   Foley MP, 2025, EUR J VASC ENDOVASC, V70, P346, DOI [10.1016/j.ejvs.2025.04.026, 10.1016/j.ejvs.2025.04.026]
   Gwilym BL, 2021, EUR J VASC ENDOVASC, V61, P636, DOI 10.1016/j.ejvs.2020.11.053
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   The ROSSINI-Platform Investigators Collaborating Group, 2024, NIHR Open Res, V4, P76
NR 5
TC 0
Z9 0
U1 0
U2 0
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 1078-5884
EI 1532-2165
J9 EUR J VASC ENDOVASC
JI Eur. J. Vasc. Endovasc. Surg.
PD SEP
PY 2025
VL 70
IS 3
BP 357
EP 358
DI 10.1016/j.ejvs.2025.05.024
EA SEP 2025
PG 2
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA 7NE7A
UT WOS:001575006100009
PM 40381725
DA 2026-07-24
ER

PT J
AU Felte, R
   Gallagher, K
   Cardenas, L
   Cipolle, M
AF Felte, R.
   Gallagher, K.
   Cardenas, L.
   Cipolle, M.
TI A CASE REVIEW SERIES OF NEGATIVE PRESSURE WOUND THERAPY WITH
   INSTILLATION AND DWELL TIME (NPWTI-D) USING HYPOCHLOROUS ACID (HOCL)
   VERSUS SODIUM HYPOCHLORITE (NAOCL) OR 0.9% NORMAL SALINE INSTILLATION IN
   COMPLEX INFECTED WOUNDS
SO WOUND REPAIR AND REGENERATION
LA English
DT Meeting Abstract
C1 [Felte, R.; Gallagher, K.; Cardenas, L.; Cipolle, M.] ChristianaCare Hlth Syst, Wilmington, DE USA.
NR 0
TC 0
Z9 0
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JUL-AUG
PY 2017
VL 25
IS 4
BP A39
EP A39
PG 1
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA FO2SH
UT WOS:000416631700168
DA 2026-07-24
ER

PT J
AU Robson, MC
   Cooper, DM
   Aslam, R
   Gould, LJ
   Harding, KG
   Margolis, DJ
   Ochs, DE
   Serena, TE
   Snyder, RJ
   Steed, DL
   Thomas, DR
   Wiersma-Bryant, L
AF Robson, Martin C.
   Cooper, Diane M.
   Aslam, Rummana
   Gould, Lisa J.
   Harding, Keith G.
   Margolis, David J.
   Ochs, Diane E.
   Serena, Thomas E.
   Snyder, Robert J.
   Steed, David L.
   Thomas, David R.
   Wiersma-Bryant, Laurel
TI Guidelines for the treatment of venous ulcers
SO WOUND REPAIR AND REGENERATION
LA English
DT Review
ID INCOMPETENT PERFORATING VEINS; PLACEBO-CONTROLLED TRIAL; OPEN SUBFASCIAL
   DIVISION; VACUUM-ASSISTED CLOSURE; TISSUE OXYGEN-TENSION; MUSCLE PUMP
   FUNCTION; LEG ULCERS; DOUBLE-BLIND; RANDOMIZED-TRIAL; WOUND-INFECTION
C1 Univ S Florida, Tampa, FL 33612 USA.
   Healthpoint Ltd, Ft Worth, TX USA.
   Univ Calif San Francisco, San Francisco, CA 94143 USA.
   Univ Texas, Med Branch, Galveston, TX 77555 USA.
   Cardiff Univ, Cardiff, Wales.
   Univ Penn, Philadelphia, PA 19104 USA.
   Univ Pittsburgh, Pittsburgh, PA USA.
   St Louis Univ, St Louis, MO 63103 USA.
   Washington Univ, St Louis, MO USA.
C3 State University System of Florida; University of South Florida;
   University of California System; University of California San Francisco;
   University of Texas System; University of Texas Medical Branch
   Galveston; Cardiff University; University of Pennsylvania; Pennsylvania
   Commonwealth System of Higher Education (PCSHE); University of
   Pittsburgh; Saint Louis University; Washington University (WUSTL)
RP Robson, MC (通讯作者)，Univ S Florida, Tampa, FL 33612 USA.
RI Harding, Keith/J-5605-2013
OI Harding, Keith/0000-0003-0048-3279; Margolis, David/0000-0002-0506-8085
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NR 221
TC 151
Z9 168
U1 0
U2 16
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV-DEC
PY 2006
VL 14
IS 6
BP 649
EP 662
DI 10.1111/j.1524-475X.2006.00174.x
PG 14
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 117KN
UT WOS:000242872100003
PM 17199831
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Kadohama, T
   Akasaka, N
   Nagamine, A
   Nakanishi, K
   Kiyokawa, K
   Goh, K
   Sasajima, T
AF Kadohama, Takayuki
   Akasaka, Nobuyuki
   Nagamine, Akira
   Nakanishi, Keisuke
   Kiyokawa, Keiko
   Goh, Kazutomo
   Sasajima, Tadahiro
TI Vacuum-assisted closure for pediatric post-sternotomy mediastinitis: Are
   low negative pressures sufficient?
SO ANNALS OF THORACIC SURGERY
LA English
DT Editorial Material
ID THERAPY
AB We present 3 cases of pediatric post-sternotomy mediastinitis treated by a vacuum-assisted closure (VAC). The patients 2 girls, aged 6 months and 10 months, and a 2-year-old boy. The onset of infection was at 9, 14, and 32 postoperative days. The culture examination detected coagulase-negative Staphylococci strains in 2 cases, and Staphylococcus aureus in 1 case. A VAC was performed at -50 mm Hg for 10, 12, and 7 days. The wounds were closed without vascularized soft tissue. A VAC under a low negative pressure is a useful and safe procedure for the management of pediatric post-sternotomy mediastinitis.
C1 Asahikawa Med Univ, Dept Surg, Asahikawa, Hokkaido, Japan.
   Asahikawa Med Univ, Dept Emergency Med, Asahikawa, Hokkaido, Japan.
C3 Asahikawa Medical University; Asahikawa Medical University
RP Kadohama, T (通讯作者)，Asahikawa Med Univ, Dept Surg, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Hokkaido, Japan.
EM tkadoha@asahikawa-med.ac.jp
OI Kadohama, Takayuki/0000-0002-5175-748X
CR Al-Sehly AA, 2005, ANN THORAC SURG, V80, P2314, DOI 10.1016/j.athoracsur.2005.05.035
   Fleck Tatjana, 2006, Interact Cardiovasc Thorac Surg, V5, P285, DOI 10.1510/icvts.2005.122424
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   SALAZARD B, 2007, J PLAST RECONSTR AES
   Sjogren Johan, 2004, Interact Cardiovasc Thorac Surg, V3, P666, DOI 10.1016/j.icvts.2004.08.003
NR 7
TC 29
Z9 34
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD MAR
PY 2008
VL 85
IS 3
BP 1094
EP 1096
DI 10.1016/j.athoracsur.2007.09.004
PG 4
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 266MZ
UT WOS:000253441500051
PM 18291211
OA Bronze
DA 2026-07-24
ER

PT J
AU Negosanti, L
   Aceti, A
   Bianchi, T
   Corvaglia, L
   Negosanti, F
   Sgarzani, R
   Morselli, PG
   Cipriani, R
   Negosanti, M
   Patrizi, A
   Faldella, G
AF Negosanti, Luca
   Aceti, Arianna
   Bianchi, Tommaso
   Corvaglia, Luigi
   Negosanti, Francesca
   Sgarzani, Rossella
   Morselli, Paolo Giovanni
   Cipriani, Riccardo
   Negosanti, Massimino
   Patrizi, Annalisa
   Faldella, Giacomo
TI Adapting a Vacuum Assisted Closure dressing to challenging wounds:
   negative pressure treatment for perineal necrotizing fasciitis with
   rectal prolapse in a newborn affected by acute myeloid leukaemia
SO EUROPEAN JOURNAL OF DERMATOLOGY
LA English
DT Article
DE necrotizing fascitiis; negative pressure therapy; neonatal infection;
   vacuum assisted closure dressing; wound care
ID PSEUDOMONAS-AERUGINOSA; THERAPY; CHILDREN
AB We report the case of a newborn with acute myeloid leukaemia, who developed perineal necrotizing fasciitis due to Pseudomonas Aeruginosa, after twenty days of life. Following surgical debridement, she was effectively treated with topical negative pressure therapy (V.A.C.(R) device) with silver foam dressings, this achieved complete closure in thirteen days. Negative pressure therapy should be considered when conventional wound care fails to achieve complete wound closure, even in neonates.
C1 [Negosanti, Luca; Sgarzani, Rossella; Morselli, Paolo Giovanni; Cipriani, Riccardo] St Orsola Marcello Malpighi Hosp, Unit Plast Surg, I-40138 Bologna, Italy.
   [Aceti, Arianna; Corvaglia, Luigi; Faldella, Giacomo] St Orsola Marcello Malpighi Hosp, Unit Neonatol & Neonatal Intens Care, I-40138 Bologna, Italy.
   [Bianchi, Tommaso] Bellaria Maggiore Hosp, Unit Dermatol, Bologna, Italy.
   [Negosanti, Francesca; Negosanti, Massimino; Patrizi, Annalisa] St Orsola Marcello Malpighi Hosp, Unit Dermatol, I-40138 Bologna, Italy.
C3 IRCCS Azienda Ospedaliero-Universitaria di Bologna; IRCCS Azienda
   Ospedaliero-Universitaria di Bologna; AUSL di Bologna; IRCCS Azienda
   Ospedaliero-Universitaria di Bologna
RP Negosanti, L (通讯作者)，St Orsola Marcello Malpighi Hosp, Unit Plast Surg, Via Massarenti 9, I-40138 Bologna, Italy.
EM luca.negosanti81@gmail.com
RI ; Aceti, Arianna/AAB-4007-2019; Negosanti, Luca/AAF-1605-2020; Sgarzani,
   Rossella/M-7495-2018
OI Annalisa, Patrizi/0000-0002-8398-0483; Aceti,
   Arianna/0000-0001-9274-985X; Negosanti, Luca/0000-0002-8110-3604;
   Sgarzani, Rossella/0000-0002-5543-8013; Negosanti,
   Massimino/0000-0001-8754-9992
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NR 13
TC 12
Z9 12
U1 0
U2 9
PU JOHN LIBBEY EUROTEXT LTD
PI MONTROUGE
PA 127 AVE DE LA REPUBLIQUE, 92120 MONTROUGE, FRANCE
SN 1167-1122
EI 1952-4013
J9 EUR J DERMATOL
JI Eur. J. Dermatol.
PD JUL-AUG
PY 2010
VL 20
IS 4
BP 501
EP 503
DI 10.1684/ejd.2010.0964
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 631LO
UT WOS:000280348700015
PM 20406723
DA 2026-07-24
ER

PT J
AU [Anonymous]
AF [Anonymous]
TI S3-Leitlinie (Langversion) Management der Mediastinitis nach
   herzchirurgischem Eingriff"*
SO THORACIC AND CARDIOVASCULAR SURGEON
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; STERNAL WOUND-INFECTION; OPEN-HEART-SURGERY;
   POST-STERNOTOMY MEDIASTINITIS; PERISTERNAL THORACIC WALL; MEDIAN
   STERNOTOMY; CARDIAC-SURGERY; POSTSTERNOTOMY MEDIASTINITIS; RISK-FACTORS;
   STAPHYLOCOCCUS-AUREUS
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NR 158
TC 1
Z9 1
U1 0
U2 4
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0171-6425
EI 1439-1902
J9 THORAC CARDIOV SURG
JI Thorac. Cardiovasc. Surg.
PD DEC
PY 2019
VL 67
SU 3
BP S131
EP S167
DI 10.1055/s-0039-3400459
PG 37
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA KA1HB
UT WOS:000505548800001
PM 31899924
DA 2026-07-24
ER

PT J
AU Varker, KA
   Ng, T
AF Varker, KA
   Ng, T
TI Management of empyema cavity with the vacuum-assisted closure device
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID WOUND CONTROL
AB Management of empyema after pulmonary resection remains a challenging problem. Along with mandatory drainage of the thoracic cavity and investigations to rule out bronchopleural fistula, a reliable method of thoracic cavity closure is needed. The open thoracic window and Eloesser flap techniques rarely represent definitive therapy. Muscle flap and thoracoplasty procedures may provide well-vascularized tissue to close bronchopleural fistula and obliterate the empyema cavity, but they are quite complex and involve significant patient morbidity. We report a case of empyema without bronchopleural fistula after lobectomy in which the vacuum-assisted closure device was used to achieve complete wound healing after open drainage.
C1 Brown Univ, Roger Williams Med Ctr, Dept Surg, Sch Med, Providence, RI 02912 USA.
C3 Brown University; Roger Williams Medical Center
RP Varker, KA (通讯作者)，424 Comprehens Canc Ctr, 410 W 12th Ave, Columbus, OH 43210 USA.
EM varker-1@medctr.osu.edu
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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   Vallieres Eric, 2002, Chest Surg Clin N Am, V12, P571, DOI 10.1016/S1052-3359(02)00019-4
NR 8
TC 39
Z9 46
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD FEB
PY 2006
VL 81
IS 2
BP 723
EP 725
DI 10.1016/j.athoracsur.2004.10.040
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 009VV
UT WOS:000235142400053
PM 16427885
DA 2026-07-24
ER

PT J
AU Türköz, R
   Dogan, A
   Türkekul, Y
   Özker, E
AF Turkoz, Riza
   Dogan, Abdullah
   Turkekul, Yasemin
   Ozker, Emre
TI Successful treatment of thoracic aortic graft infection by omental flap
   following vacuum-assisted closure therapy
SO JOURNAL OF CARDIAC SURGERY
LA English
DT Article
DE aortic graft infection; omental transposition; vacuum-assisted closure
AB Background Postoperative thoracic aortic graft infection (TAGI) is a serious and potentially fatal complication. The classical approach is to replace the infected graft. However, this approach has a high mortality rate. Alternatively, treatment of TAGI without graft replacement can be performed Method Herein, we present a 72-year-old case with mediastinitis and graft infection after type A aortic dissection operation and successful treatment using omental flap coverage following vacuum-assisted wound closure therapy without graft replacement. Conclusion The patient had an uneventful postoperative course and remains infection-free to date.
C1 [Dogan, Abdullah] Acibadem Bakirkoy Hosp, Dept Cardiovasc Surg, Istanbul, Turkey.
   [Turkekul, Yasemin] Univ Hlth Sci, Istanbul Training & Res Hosp, Dept Cardiovasc Surg, Istanbul, Turkey.
   [Ozker, Emre] Altunizade Acibadem Hosp, Dept Wound Care, Istanbul, Turkey.
C3 Acibadem Hospitals Group; Acibadem Hastaneleri; University of Health
   Sciences Turkey; Istanbul Training & Research Hospital
RP Dogan, A (通讯作者)，Halit Ziya Usakligil Cad 1 Bakirkoy, TR-34140 Istanbul, Turkey.
EM doganabdullah65@gmail.com
RI ; Doğan, Abdullah/OEN-7631-2025
OI Turkoz, Riza/0000-0002-6617-2601; Doğan, Abdullah/0000-0002-7446-2502
CR Bianco V, 2018, J CARDIAC SURG, V33, P658, DOI 10.1111/jocs.13792
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   Umminger J, 2016, EUR J CARDIO-THORAC, V50, P660, DOI 10.1093/ejcts/ezw150
NR 8
TC 1
Z9 1
U1 0
U2 12
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0886-0440
EI 1540-8191
J9 J CARDIAC SURG
JI J. Card. Surg.
PD OCT
PY 2020
VL 35
IS 10
BP 2857
EP 2859
DI 10.1111/jocs.14884
EA JUL 2020
PG 3
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA NT5YX
UT WOS:000552622100001
PM 32720391
DA 2026-07-24
ER

PT J
AU Brett, D
AF Brett, Dave
TI A PROSPECTIVE, RANDOMISED, INTRA-PATIENT, COMPARATIVE, OPEN,
   MULTI-CENTRE STUDY TO EVALUATE THE EFFICACY OF A SINGLE-USE NEGATIVE
   PRESSURE WOUND THERAPY (NPWT) SYSTEM☆ ON THE PREVENTION OF
   POSTSURGICAL INCISION HEALING COMPLICATIONS IN PATIENTS UNDERGOING
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
EM dave.brett@smith-nephew.com
CR Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Reddix Robert N Jr, 2009, Am J Orthop (Belle Mead NJ), V38, P446
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
NR 3
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2015
VL 42
IS 3
SU S
MA RS15-009
BP S57
EP S57
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA DR7WG
UT WOS:000380109800151
DA 2026-07-24
ER

PT J
AU Costa, ML
   Achten, J
   Knight, R
AF Costa, M. L.
   Achten, J.
   Knight, R.
TI Effect of Incisional Negative Pressure Wound Therapy vs StandardWound
   Dressing on Deep Surgical Site Infection After Surgery for Lower Limb
   Fractures Associated With Major Trauma: The WHIST Randomized Clinical
   Trial (vol 323, pg 519, 2020)
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Correction
RI Achten, Juul/KUD-8515-2024
OI Costa, Matthew/0000-0003-3644-1388
CR Oh NA, 2020, JAMA-J AM MED ASSOC, V324, P995, DOI 10.1001/jama.2020.8415
NR 1
TC 1
Z9 1
U1 0
U2 1
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD JUL 20
PY 2021
VL 326
IS 3
BP 279
EP 279
DI 10.1001/jama.2021.10237
PG 1
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA TP4YG
UT WOS:000677602400029
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Singh, K
   Samartzis, D
   Heller, JG
   An, HS
   Vaccaro, AR
AF Singh, K
   Samartzis, D
   Heller, JG
   An, HS
   Vaccaro, AR
TI The management of complex soft-tissue defects after spinal
   instrumentation
SO JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; TRAPEZIUS MUSCULOCUTANEOUS FLAP; POSTOPERATIVE
   WOUND INFECTIONS; PARASPINOUS MUSCLE FLAPS; MYOCUTANEOUS FLAP; OMENTAL
   FLAP; RISK-FACTORS; LOWER BACK; VERTEBRAL OSTEOMYELITIS; RECONSTRUCTIVE
   SURGERY
C1 Rush Univ, Med Ctr, Dept Orthopaed Surg, Chicago, IL 60612 USA.
C3 Rush University
RP Singh, K (通讯作者)，Rush Univ, Med Ctr, Dept Orthopaed Surg, 1725 W Harrison Pkwy, Chicago, IL 60612 USA.
EM kern.singh@rushortho.com
RI Samartzis, Dino/F-3359-2010
OI Samartzis, Dino/0000-0002-7473-1311; Heller, John/0009-0009-2595-7267
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NR 90
TC 27
Z9 27
U1 0
U2 17
PU BRITISH EDITORIAL SOC BONE & JOINT SURGERY
PI LONDON
PA 22 BUCKINGHAM STREET, LONDON WC2N 6ET, ENGLAND
SN 0301-620X
EI 2044-5377
J9 J BONE JOINT SURG BR
JI J. Bone Joint Surg.-Br. Vol.
PD JAN
PY 2006
VL 88B
IS 1
BP 8
EP 15
DI 10.1302/0301-620X.88B1.16837
PG 8
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 005KN
UT WOS:000234821200002
PM 16365112
DA 2026-07-24
ER

PT J
AU Stechmiller, JK
   Kilpadi, DV
   Childress, B
   Schultz, GS
AF Stechmiller, Joyce K.
   Kilpadi, Deepak V.
   Childress, Beverly
   Schultz, Gregory S.
TI Effect of Vacuum-Assisted Closure Therapy on the expression of cytokines
   and proteases in wound fluid of adults with pressure ulcers
SO WOUND REPAIR AND REGENERATION
LA English
DT Letter
ID MATRIX-METALLOPROTEINASE; TISSUE INHIBITOR; HUMAN SKIN; FIBROBLASTS;
   INDUCTION; TIMP-1; GROWTH; MMP-2
C1 Univ Florida, Coll Nursing Adult & Elderly Nursing, Gainesville, FL 32605 USA.
   Kinet Concepts Inc, San Antonio, TX USA.
   Univ Florida, Coll Nursing, Gainesville, FL 32611 USA.
   Univ Florida, Coll Med, Gainesville, FL 32611 USA.
C3 State University System of Florida; University of Florida; State
   University System of Florida; University of Florida; State University
   System of Florida; University of Florida
RP Stechmiller, JK (通讯作者)，Univ Florida, Coll Nursing Adult & Elderly Nursing, POB 100187, Gainesville, FL 32605 USA.
EM stechjk@nursing.ufl.edu
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NR 30
TC 67
Z9 86
U1 1
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAY-JUN
PY 2006
VL 14
IS 3
BP 371
EP 374
DI 10.1111/j.1743-6109.2006.00134.x
PG 4
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 057EY
UT WOS:000238580300019
PM 16808818
DA 2026-07-24
ER

PT J
AU Patton, D
   Avsar, P
   Wilson, P
   Mairghani, M
   O'Connor, T
   Nugent, L
   Moore, Z
AF Patton, Declan
   Avsar, Pinar
   Wilson, Pauline
   Mairghani, Maisoon
   O'Connor, Tom
   Nugent, Linda
   Moore, Zena
TI Treatment of diabetic foot ulcers: review of the literature with regard
   to the TIME clinical decision support tool
SO JOURNAL OF WOUND CARE
LA English
DT Review
DE debridement; diabetic foot ulcer; negative pressure wound therapy;
   ischaemia; wound; wound care; wound dressing; wound healing
ID PRESSURE WOUND THERAPY; VACUUM-ASSISTED CLOSURE; BED PREPARATION;
   MANAGEMENT; DRESSINGS; METAANALYSIS; DEBRIDEMENT; HONEY; PAIN; SKIN
AB Objective: The aim of this clinically orientated paper is to offer an overview of diabetic foot ulcer (DFU) dressings generally, and more specifically, their use in the treatment of DFUs.
   Method: The TIME clinical decision support tool (CDST) has been used as a clinical tool that can help clinicians bring together the different aspects of dressings for DFU treatment into a holistic approach to patient care.
   Results: DFUs are often difficult to heal, are painful and impact negatively on the individual's quality of life. Most DFU dressings are designed to support the healing of hard-to-heal wounds and represent one part of the management of DFUs. Apart from providing a moist environment, absorbing increased exudate, enhancing granulation and assisting in autolysis, the dressings need to be cost-effective. Wound dressing selection is based on clinical knowledge that ensures the dressing is most appropriate for the individual and the wound, taking into account the comorbidities that the individual may have.
   Conclusion: This paper has highlighted how the use of the TIME CDST model can enhance clinical care and is a further tool clinicians should consider when developing and executing DFU treatment plans. Future research needs to focus on large multicentre studies using robust methodologies, given the current gaps in the evidence, to determine the effectiveness of dressing products for DFUs.
C1 [Patton, Declan; O'Connor, Tom; Nugent, Linda; Moore, Zena] Univ Med & Hlth Sci, Sch Nursing & Midwifery, Royal Coll Surg Ireland RCSI, Dublin, Ireland.
   [Patton, Declan; Avsar, Pinar; Wilson, Pauline; O'Connor, Tom; Moore, Zena] RCSI Univ Med & Hlth Sci, Skin Wounds & Trauma Res Ctr, Sch Nursing & Midwifery, Dublin, Ireland.
   [Patton, Declan; O'Connor, Tom; Nugent, Linda; Moore, Zena] Fakeeh Coll Hlth Sci, Jeddah, Saudi Arabia.
   [Patton, Declan] Univ Wollongong, Fac Sci Med & Hlth, Wollongong, NSW, Australia.
   [Patton, Declan; O'Connor, Tom] Griffith Univ, Nathan, Qld, Australia.
   [Mairghani, Maisoon] RCSI Univ Med & Hlth Sci, Publ Hlth & Epidemiol, Dublin, Ireland.
   [O'Connor, Tom; Moore, Zena] Lida Inst, Shanghai, Peoples R China.
   [Moore, Zena] Monash Univ, Fac Med Nursing & Hlth Sci, Melbourne, Vic, Australia.
   [Moore, Zena] Univ Ghent, Fac Med & Hlth Sci, Dept Publ Hlth, Ghent, Belgium.
   [Moore, Zena] Univ Wales Coll Cardiff, Cardiff, Wales.
C3 Royal College of Surgeons in Ireland - RCSI; Royal College of Surgeons
   in Ireland - RCSI; Fakeeh College for Medical Sciences; University of
   Wollongong; Griffith University; Royal College of Surgeons in Ireland -
   RCSI; Monash University; Ghent University; Cardiff University
RP Avsar, P (通讯作者)，RCSI Univ Med & Hlth Sci, Skin Wounds & Trauma Res Ctr, Sch Nursing & Midwifery, Dublin, Ireland.
EM pinaraysar@rcsi.com
RI Nugent, Linda Elizabeth/P-1922-2015
OI Nugent, Linda Elizabeth/0000-0001-7480-8545; AVSAR,
   PINAR/0000-0002-7637-1700; Patton, Declan/0000-0003-1018-2605
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NR 94
TC 5
Z9 6
U1 1
U2 12
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD SEP
PY 2022
VL 31
IS 9
BP 771
EP 779
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 4R2DS
UT WOS:000856579500006
PM 36113541
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Ogur, HU
   Kapukaya, R
   Çiloglu, O
   Külahci, O
   Tekbas, VT
   Yörükoglu, A
AF Ogur, Hasan Ulas
   Kapukaya, Rana
   Ciloglu, Osman
   Kulahci, Ozgur
   Tekbas, Volkan Tolga
   Yorukoglu, Abdulkerim
TI Treatment of open wounds secondary to trauma using polyurethane foams
   with boric acid particles
SO ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA &
   EMERGENCY SURGERY
LA English
DT Article
DE Boric acid particle; boron foams; the negative pressure wound therapy
ID VACUUM-ASSISTED CLOSURE; NEGATIVE-PRESSURE; IN-VITRO; SILVER; BORON;
   ANTISEPTICS; MECHANISMS; THERAPY
AB BACKGROUND: To investigate the efficacy of new foams with boric acid particles combined with a negative pressure wound treatment (NPWT) system in open fractures with tissue defects secondary to trauma. METHODS: Forty-nine patients with open fractures secondary to trauma with soft tissue defects who were admitted between 2016 and 2018 were included in the study. Patients were examined in two groups. In Group 1, boric acid-impregnated foams combined with the NPWT system were used in 27 patients, and in Group 2, silver nitrate-impregnated foams combined with NPWT systems were used in 22 patients. In addition to evaluating the broad-spectrum antibacterial feature of silver nitrate, the antimicrobial, angiogenetic, and epithelializing effects of boric acid were investigated macroscopically and histopathologically. RESULTS: A reduction in wound size and granulation was observed in each group. Macroscopically, the reduction in wound size, epithelialization and granulation were pronounced in Group 1 and in Group 2. Microscopically, the number of fibroblasts, collagen synthesis, and angiogenesis were significantly increased in Group 1 compared with Group 2. CONCLUSION: In this clinical trial, both the broad spectrum antimicrobial feature of boric acid and its positive effect on the cells responsible for wound healing were found to be an alternative compared with silver nitrate. The use of new foams with boric acid particles combined with the NPWT system may be a good alternative method in the treatment of open wounds due to trauma.
C1 [Ogur, Hasan Ulas; Ciloglu, Osman; Tekbas, Volkan Tolga] Adana City Training & Res Hosp, Dept Orthopaed & Traumatol, Adana, Turkey.
   [Kapukaya, Rana] Adana City Training & Res Hosp, Dept Plast & Reconstruct Surg, Adana, Turkey.
   [Kulahci, Ozgur] Adana City Training & Res Hosp, Dept Med Pathol, Adana, Turkey.
   [Yorukoglu, Abdulkerim] Natl Boron Inst, Ankara, Turkey.
C3 Adana Numune Training & Research Hospital; Adana Numune Training &
   Research Hospital; Adana Numune Training & Research Hospital
RP Ogur, HU (通讯作者)，Adana Sehir Egitim & Arastirma Hastanesi, Ortopedi & Travmatol Klin, Adana, Turkey.
EM hasanulas@yahoo.com
RI KAPUKAYA, RANA/HKE-5389-2023; Yörükoğlu, Abdulkerim/AAR-5664-2021;
   ciloglu, osman/QKY-0989-2026; Külahcı, Özgür/AGG-0591-2022
OI KAPUKAYA, RANA/0000-0001-9709-328X; Tekbaş, Volkan
   Tolga/0000-0002-6462-2728; 
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NR 30
TC 3
Z9 4
U1 0
U2 6
PU TURKISH ASSOC TRAUMA EMERGENCY SURGERY
PI ISTANBUL
PA KOPRULU MEHMET PASA SOC, DENIZ ABDAL MAH, DADASOGLU AP, 25-1 SEHREMINI,
   ISTANBUL, 00000, TURKEY
SN 1306-696X
J9 ULUS TRAVMA ACIL CER
JI Ulus. Travma Acil Cerrahi Derg.
PD NOV
PY 2021
VL 27
IS 6
BP 624
EP 630
DI 10.14744/tjtes.2020.38613
PG 7
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA XF1GS
UT WOS:000723826200004
PM 34710221
OA hybrid
DA 2026-07-24
ER

PT J
AU Looby, MA
   Vogel, RI
   Bangdiwala, A
   Hyer, B
   Das, K
AF Looby, Maureen Ayers
   Vogel, Rachel Isaksson
   Bangdiwala, Ananta
   Hyer, Barbara
   Das, Kamalini
TI Prophylactic Negative Pressure Wound Therapy in Obese Patients Following
   Cesarean Delivery
SO SURGICAL INNOVATION
LA English
DT Article
DE tissue engineering; surgical oncology; evidence based medicine; surgery
ID VACUUM-ASSISTED CLOSURE; COMPLICATIONS
AB Objective. Negative pressure therapy (NPT) offers the potential to reduce infection in obese patients. The goal of this study was to explore the association between NPT use and infection after cesarean delivery among obese women. Methods: We initiated a hospital protocol wherein women with a body mass index (BMI) of 40 kg/m(2) or greater who delivered after January 1, 2011 were to receive NPT following cesarean section. A retrospective comparison of surgical site infection (SSI) in women receiving the intervention to a similar group with a BMI of 40 kg/m(2) or greater, a historical control group of women who delivered before January 1, 2011. Incidence of SSI was compared between time periods using logistic regression models. Results. A total of 233 patients in the preintervention (control) group and 234 patients in the intervention group were included in the analysis. In the control group, 23 (9.9%) developed SSI, compared with 13 (5.6%) in the intervention group. After adjustment for potential confounding factors, women in the postintervention period experienced a statistically significant reduction in SSI rates (adjusted odds ratio =0.45, 95% CI = 0.22-0.95); P = .04). Conclusion. Implementation of a hospital protocol of NPT following cesarean delivery in obese women resulted in reduced incidence of postoperative SSI. This study suggests that using NPT after cesarean delivery in women with a BMI 40 kg/m(2) is an efficacious method to reduce incidence of postoperative wound infections.
C1 [Looby, Maureen Ayers; Hyer, Barbara; Das, Kamalini] HealthPartners Dept Obstet & Gynecol, 205 South Wabasha St, St Paul, MN 55107 USA.
   [Looby, Maureen Ayers; Vogel, Rachel Isaksson; Bangdiwala, Ananta] Univ Minnesota, Minneapolis, MN USA.
C3 University of Minnesota System; University of Minnesota Twin Cities
RP Das, K (通讯作者)，HealthPartners Dept Obstet & Gynecol, 205 South Wabasha St, St Paul, MN 55107 USA.
EM kamalini.x.das@healthpartners.com
OI Das, Kamalini/0000-0003-4343-467X; Vogel, Rachel/0000-0003-0149-8464
FU Regions Hospital Red Fund from HealthPartners Medical Group [RG
   1415301]; NIH [P30 CA77598]; National Center for Advancing Translational
   Sciences of the National Institutes of Health [UL1TR000114]
FX The author(s) disclosed receipt of the following financial support for
   the research, authorship, and/or publication of this article: This study
   was supported in part by the Regions Hospital Red Fund RG 1415301 from
   HealthPartners Medical Group. Statistical data analysis was supported in
   part by NIH grant P30 CA77598 utilizing the Biostatistics and
   Bioinformatics Core shared resource of the Masonic Cancer Center,
   University of Minnesota and by the National Center for Advancing
   Translational Sciences of the National Institutes of Health Award Number
   UL1TR000114.
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NR 18
TC 10
Z9 12
U1 0
U2 2
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1553-3506
EI 1553-3514
J9 SURG INNOV
JI Surg. Innov.
PD FEB
PY 2018
VL 25
IS 1
BP 43
EP 49
DI 10.1177/1553350617736652
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FX3SP
UT WOS:000425992900007
PM 29090986
DA 2026-07-24
ER

PT J
AU Seretis, K
   Bounas, N
AF Seretis, Konstantinos
   Bounas, Nikolaos
TI Securing skin grafts: A network meta-analysis
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Review
DE Skin grafting; Graft; Meta-analysis; Fixation; Wound healing; Review
ID PRESSURE WOUND THERAPY; VACUUM-ASSISTED CLOSURE; FIBRIN SEALANT;
   CLINICAL-TRIAL; BURN WOUNDS; LEG ULCERS; THICKNESS; INTEGRATION;
   EFFICACY; MECHANISM
AB Background: Skin grafting is one of the most common procedures in plastic surgery. However, there are no defined guidelines for optimal fixation. The aim of this network metaanalysis (NMA) was to consolidate existing evidence by comparing various graft securing methods and determining the most effective approach for clinical practice. Methods: An NMA was conducted using a predetermined protocol after searching several electronic databases from inception to October 2023 for studies examining skin grafting fixation outcomes in adults. Results: A total of 27 studies were included in the analysis involving 1937 patients. Negative pressure wound therapy (NPWT) was the only method to significantly improve graft take percentages in comparison with the other modalities, whereas tie-over bolster (TOB) provided the worst results in take rates when examined as events. Fibrin glue (FIB) and TOB reduced hematoma and seroma rates when data were investigated in conjunction. Conclusions: NPWT appears to be the most effective for skin graft adherence as opposed to traditional techniques. Its cost-effectiveness remains unclear, as NPWT is a relatively costly intervention compared with other methods. FIB and TOB are methods that can serve as a method of reducing hematoma and seroma rates in patients at high risk of bleeding. Level of evidence: I. (c) 2024 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
C1 [Seretis, Konstantinos; Bounas, Nikolaos] Univ Ioannina, Med Sch, Dept Plast Surg, Ioannina, Greece.
   [Seretis, Konstantinos] Leoforos St Niarchou, Ioannina 45500, Greece.
C3 University of Ioannina
RP Seretis, K (通讯作者)，Leoforos St Niarchou, Ioannina 45500, Greece.
EM drseretis@uoi.gr
RI Seretis, Konstantinos/GPX-2431-2022; Bounas, Nikolaos/HQY-5525-2023
OI Seretis, Konstantinos/0000-0002-1844-1264; Bounas,
   Nikolaos/0000-0003-1243-5346
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NR 62
TC 6
Z9 6
U1 0
U2 5
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD SEP
PY 2024
VL 96
BP 146
EP 157
DI 10.1016/j.bjps.2024.07.005
EA JUL 2024
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA A9M5K
UT WOS:001285708600001
PM 39089211
DA 2026-07-24
ER

PT J
AU Ulusoy, S
   Kilinç, I
   Oruç, M
   Özdemir, B
   Ergani, HM
   Keskin, ÖH
   Özdemir, G
AF Ulusoy, Serap
   Kilinc, Ibrahim
   Oruc, Mustafa
   Ozdemir, Buket
   Ergani, Hasan Murat
   Keskin, Omer Halit
   Ozdemir, Guzelali
TI Analysis of wound types and wound care methods after the 2023
   Kahramanmaras earthquake
SO JOINT DISEASES AND RELATED SURGERY
LA English
DT Article
DE Collapsed buildings; earthquake; musculoskeletal injury; wound care
   wound
ID VACUUM-ASSISTED CLOSURE; MUSCULOSKELETAL INJURIES; HYPOCHLOROUS ACID;
   MANAGEMENT; THERAPY; REPAIR; OXYGEN
AB Objectives: This study aims to investigate the types of wounds and wound care in earthquake victims rescued from collapsed buildings after the 2023 Kahramanmaras earthquake.Patients and methods: Between February 8th, 2023 and March 1st, 2023, a total of 94 patients (46 males, 48 females; mean age: 40.2 & PLUSMN;15.5 years; range, 16 to 77 years) with earthquake-related wounds who were trapped under rubble were retrospectively analyzed. Data including age, sex, duration of being trapped under rubble, type and location of the wound, bacterial cultures from deep tissue, and wound care methods used were recorded.Results: The mean duration of being trapped under rubble was 58 & PLUSMN;38.1 h. Wounds were most commonly located on the lower extremities, followed by the upper extremities. The most common type of wounds were abrasions, followed by necrotic wounds due to crushing. Wound and skin antiseptics, debridement and negative pressure wound therapy (NPWT) were the most common wound care methods used.Conclusion: Various types of injuries and wounds may occur after natural disasters. Chronic wound care is as important as the management of life-threatening acute pathologies. Preparations should be made properly for the long-term treatment of patients after disasters. Methods such as NPWT, debridement creams containing collagenase, wound and skin antiseptics, and hyperbaric oxygen therapy can provide satisfactory short-term results. A broader and more intense application of these treatments is thought to be beneficial, particularly in crush injuries.
C1 [Ulusoy, Serap; Kilinc, Ibrahim; Oruc, Mustafa; Ozdemir, Buket] Ankara Bilkent City Hosp, Dept Gen Surg, Ankara, Turkiye.
   [Ergani, Hasan Murat] Univ Hlth Sci, Ankara Bilkent City Hosp, Dept Plast Reconstruct & Aesthet Surg, Ankara, Turkiye.
   [Keskin, Omer Halit; Ozdemir, Guzelali] Ankara Bilkent City Hosp, Dept Orthoped & Traumatol, Ankara, Turkiye.
C3 University of Health Sciences Turkey
RP Ulusoy, S (通讯作者)，Ankara Bilkent Sehir Hastanesi, Gen Cerrahi Klin, TR-06800 Ankara, Turkiye.
EM serapulusoy13@gmail.com
RI Ulusoy, Serap/JBS-7863-2023; Ergani, Hasan Murat/ADG-1790-2022; Keskin,
   Omer Halit/JNR-9917-2023; Oruc, Mustafa/LXW-0152-2024; Ozdemir,
   Guzelali/LBH-4760-2024; Özdemir Ulusoy, Bahar/ITU-9764-2023
OI Ulusoy, Serap/0000-0001-9014-7070; Ergani, Hasan
   Murat/0000-0002-0305-7032; Keskin, Omer Halit/0000-0003-2402-8465; Oruc,
   Mustafa/0000-0002-7918-1689; ALTUN ÖZDEMİR, BUKET/0000-0002-1043-8108; 
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
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NR 36
TC 16
Z9 20
U1 0
U2 2
PU TURKISH JOINT DISEASES FOUNDATION
PI CANKAYA
PA MUSTAFA KEMAL MAHALLESI, DUMLUPINAR BULVARI 274-2 C2 BLOK OFIS, 5,
   CANKAYA, ANKARA, TURKEY
EI 2687-4792
J9 JOINT DIS RELAT SURG
JI Joint Dis. Relat. Surg.
PY 2023
VL 34
IS 2
BP 488
EP 496
DI 10.52312/jdrs.2023.1128
PG 9
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA K9EW5
UT WOS:001019406000034
PM 37462657
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Li, XC
   Cui, JL
   Maharjan, S
   Yu, X
   Lu, LJ
   Gong, X
AF Li, Xiucun
   Cui, Jianli
   Maharjan, Suraj
   Yu, Xin
   Lu, Laijin
   Gong, Xu
TI Neo-digit functional reconstruction of mutilating hand injury using
   transplantation of multiple composite tissue flaps
SO MEDICINE
LA English
DT Article
DE composite tissue flap transplantation; functional reconstruction;
   mutilating hand injury
ID VACUUM-ASSISTED CLOSURE; UPPER EXTREMITY; REPLANTATION; RELIABILITY;
   VALIDITY; DEFECTS; THERAPY; JOINT
AB Purpose: Functional reconstruction of mutilating hand injuries poses a challenge to the surgeon. We present our experience with use of multiple composite tissue flaps transplant for functional reconstruction of hand in patients with mutilating hand injuries. The associated merits and demerits of these surgical approaches are briefly discussed.
   Methods: From August 2004 to October 2014, functional reconstruction of hand with transplantation of multiple composite tissue flaps was performed in 8 patients. These included the toe with dorsal pedis artery flap, the reverse posterior interosseous artery flap, and the anterolateral thigh flap. Mean interval from injury to functional reconstruction was 10.6 days.
   Results: All transplanted skin flaps and reconstructed neofingers survived completely. Only 1 patient developed wound infection at the recipient site (hand), which resolved without any debridement or revision surgery. At the donor site (foot), partial skin necrosis was observed in 1 patient, which healed with local wound care. In other patients, all wounds healed without any complications. The average range of movement at the neofinger metacarpophalangeal and interphalangeal joints was 38 degrees and 73 degrees, respectively. None of the patients required revision surgery.
   Conclusion: Use of negative pressure wound therapy and multiple composite tissue flap transplantation appears to be an effective strategy for hand functional reconstruction in patients with mutilating hand injuries. Among the multiple composite tissue flaps, use of toe transplantation combined with reverse posterior interosseous artery flap appears to be the best option.
C1 [Li, Xiucun; Cui, Jianli; Maharjan, Suraj; Yu, Xin; Lu, Laijin; Gong, Xu] Jilin Univ, Hosp 1, Dept Hand & Foot Surg, Changchun 130021, Jilin, Peoples R China.
C3 Jilin University
RP Lu, LJ; Gong, X (通讯作者)，Jilin Univ, Hosp 1, Dept Hand & Foot Surg, Changchun 130021, Jilin, Peoples R China.
EM triumphlixc@163.com; 13944099151@163.com
RI Li, xiucun/AAI-9002-2020
OI Li, xiucun/0000-0002-3260-6299
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NR 31
TC 5
Z9 8
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD JUL
PY 2016
VL 95
IS 27
AR e4179
DI 10.1097/MD.0000000000004179
PG 8
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA DS1QW
UT WOS:000380372400088
PM 27399142
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Timmers, MS
   Graafland, N
   Bernards, AT
   Nelissen, RGHH
   van Dissel, JT
   Jukema, GN
AF Timmers, Michael S.
   Graafland, Niels
   Bernards, Alexandra T.
   Nelissen, Rob G. H. H.
   van Dissel, Jaap T.
   Jukema, Gerrolt N.
TI Negative pressure wound treatment with polyvinyl alcohol foam and
   polyhexanide antiseptic solution instillation in posttraumatic
   osteomyelitis
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; CLINICAL-EXPERIENCE; THERAPY; INFECTIONS;
   TRIAL; BONE; FOOT
AB In a retrospective, case control cohort study an assessment was made of the clinical outcome of patients with osteomyelitis treated with a new modality of negative pressure wound therapy, so called negative pressure instillation therapy. In this approach, after surgical debridement, a site of osteomyelitis is treated with negative pressure of at least 300 mmHg applied through polyvinyl alcohol dressing. The polyvinyl alcohol foam is irrigated through the tubes three times a day with a polyhexanide antiseptic solution. In 30 patients ( 14 males; mean age 52 [ range, 26-81]) admitted between 1999 and 2003 with osteomyelitis of the pelvis or lower extremity, we assessed time to wound closure, number of surgical procedures and rate of recurrence of infection as well as need for rehospitalizations. For comparison, a control group of 94 patients ( males, 58; mean age 47 [ range, 9-85]), matched for site and severity of osteomyelitis, was identified in hospital records between 1982 and 2002. These patients underwent standard surgical debridement, implantation of gentamicin polymethylmethacrylate beads and long-term intravenous antibiotics. In the Instillation group the rate of recurrence of infection was 3/30 (10%), whereas 55/93 (58.5%) of the controls had a recurrence (p < 0.0001). Moreover, in those treated with instillation the total duration of hospital stay was shorter and number of surgical procedures smaller as compared with the controls ( all p < 0.0001). We conclude that in posttraumatic osteomyelitis negative pressure instillation therapy reduces the need for repeated surgical interventions in comparison with the present standard approach.
C1 [Timmers, Michael S.; Graafland, Niels; Jukema, Gerrolt N.] Free Univ Amsterdam, Dept Trauma Surg, Med Ctr, Amsterdam, Netherlands.
   [Timmers, Michael S.; Jukema, Gerrolt N.] Leiden Univ, Sect Traumatol, Dept Surg, Med Ctr, Leiden, Netherlands.
   [Bernards, Alexandra T.] Leiden Univ, Med Ctr, Dept Med Microbiol, Leiden, Netherlands.
   [Nelissen, Rob G. H. H.] Leiden Univ, Med Ctr, Dept Orthopaed Surg, Leiden, Netherlands.
   [van Dissel, Jaap T.] Leiden Univ, Med Ctr, Dept Infect Dis, Leiden, Netherlands.
C3 Vrije Universiteit Amsterdam; Leiden University - Excl LUMC; Leiden
   University; Leiden University Medical Center (LUMC); Leiden University -
   Excl LUMC; Leiden University; Leiden University Medical Center (LUMC);
   Leiden University - Excl LUMC; Leiden University; Leiden University
   Medical Center (LUMC); Leiden University - Excl LUMC; Leiden University;
   Leiden University Medical Center (LUMC)
RP Jukema, GN (通讯作者)，Vrije Univ Amsterdam, Med Ctr, Dept Trauma Surg, NL-1007 MB Amsterdam, Netherlands.
EM g.jukema@vumc.nl
RI Nelissen, Rob/AAD-8134-2020
OI Nelissen, Rob/0000-0003-1228-4162
FU Kinetic Concepts Inc. (KCI), San Antonio, TX
FX Conflict of interest: M. S. Timmers, N. M. Graafland, A. T. Bernards, J.
   T. van Dissel, and G. N. Jukema received unrestricted research grants
   from Kinetic Concepts Inc. (KCI), San Antonio, TX. KCI did not provide
   funding for the study reported in this paper.
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   VAC THERAPY CLIN GUI
NR 29
TC 101
Z9 116
U1 0
U2 9
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR-APR
PY 2009
VL 17
IS 2
BP 278
EP 286
DI 10.1111/j.1524-475X.2009.00458.x
PG 9
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 418ZJ
UT WOS:000264188600017
PM 19320897
DA 2026-07-24
ER

PT J
AU Meybodi, F
   Sedaghat, N
   French, J
   Keighley, C
   Mitchell, D
   Elder, E
AF Meybodi, Farid
   Sedaghat, Negin
   French, James
   Keighley, Caitlin
   Mitchell, David
   Elder, Elisabeth
TI Implant salvage in breast reconstruction with severe peri-prosthetic
   infection
SO ANZ JOURNAL OF SURGERY
LA English
DT Article
DE breast implant; breast reconstruction; infection
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; NEGATIVE-PRESSURE;
   IN-VITRO; MANAGEMENT; INSTILLATION; STRATEGIES; EXPANDER; IMPACT
AB BackgroundAlthough treatment of mild peri-prosthetic infection in implant-based breast reconstruction results in high rates of resolution, successful management of severe peri-prosthetic infection remains a significant challenge.
   MethodsIn this case series, a protocol utilizing a novel dressing - negative pressure wound therapy with instillation (NPWTi) - for the management of severe peri-prosthetic infection in breast reconstruction patients is described. This is an operative technique involving: (i) explantation of the breast prosthesis and application of the NPWTi dressing to the implant pocket; (ii) change of the NPWTi dressing; (iii) intraoperative fluid/tissue cultures; and (iv) reimplantation of the breast prosthesis when cultures yield no growth.
   ResultsThis protocol was utilized in six cases of severe peri-prosthetic infection in five patients with immediate breast reconstruction for breast cancer or risk-reducing surgery. Cultures of fluid/tissue grew typical and/or unusual organisms. Only one case did not yield an organism. The hospital length of stay upon completion of the protocol ranged from 7-16 days (mean, 12 days). Successful implant salvage was achieved in five of six cases. The protocol was aborted in one case to allow for completion of adjuvant chemotherapy.
   ConclusionsEarly findings from this case series suggest that in cases of severe peri-prosthetic infection this novel operative protocol may result in successful implant salvage for breast reconstruction patients. Further studies are needed to more fully elaborate the role of NPWTi to achieve implant salvage in challenging cases of peri-prosthetic infection.
C1 [Meybodi, Farid; Sedaghat, Negin; French, James; Elder, Elisabeth] Westmead Hosp, Westmead Breast Canc Inst, Sydney, NSW, Australia.
   [Keighley, Caitlin; Mitchell, David] Westmead Hosp, Ctr Infect Dis & Microbiol, Sydney, NSW, Australia.
C3 NSW Health; Westmead Hospital; University of Sydney; University of
   Sydney; NSW Health; Westmead Hospital
RP Meybodi, F (通讯作者)，Westmead Breast Canc Inst, POB 143, Westmead, NSW 2145, Australia.
EM faridmey@gmail.com
RI Sedaghat, Negin/AAX-4453-2021; Elder, Elisabeth/ABS-2803-2022
OI Elder, Elisabeth/0000-0002-6686-9898; Keighley,
   Caitlin/0000-0002-8892-3488
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NR 29
TC 23
Z9 25
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1445-1433
EI 1445-2197
J9 ANZ J SURG
JI ANZ J. Surg.
PD DEC
PY 2017
VL 87
IS 12
BP E293
EP E299
DI 10.1111/ans.13379
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FO9IR
UT WOS:000417201700013
PM 26572237
DA 2026-07-24
ER

PT J
AU Baltzis, D
   Eleftheriadou, I
   Veves, A
AF Baltzis, Dimitrios
   Eleftheriadou, Ioanna
   Veves, Aristidis
TI Pathogenesis and Treatment of Impaired Wound Healing in Diabetes
   Mellitus: New Insights
SO ADVANCES IN THERAPY
LA English
DT Review
DE Diabetes mellitus; Foot ulceration; Ulcer treatment strategies; Wound
   healing
ID ENDOTHELIAL PROGENITOR CELLS; HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED
   CLOSURE; GROWTH-FACTOR; FOOT ULCERS; MATRIX-METALLOPROTEINASES;
   NEUROPATHIC ULCERS; MAST-CELLS; ANGIOGENESIS; MANAGEMENT
AB Diabetic foot ulcers (DFUs) are one of the most common and serious complications of diabetes mellitus, as wound healing is impaired in the diabetic foot. Wound healing is a dynamic and complex biological process that can be divided into four partly overlapping phases: hemostasis, inflammation, proliferative and remodeling. These phases involve a large number of cell types, extracellular components, growth factors and cytokines. Diabetes mellitus causes impaired wound healing by affecting one or more biological mechanisms of these processes. Most often, it is triggered by hyperglycemia, chronic inflammation, micro- and macro-circulatory dysfunction, hypoxia, autonomic and sensory neuropathy, and impaired neuropeptide signaling. Research focused on thoroughly understanding these mechanisms would allow for specifically targeted treatment of diabetic foot ulcers. The main principles for DFU treatment are wound debridement, pressure off-loading, revascularization and infection management. New treatment options such as bioengineered skin substitutes, extracellular matrix proteins, growth factors, and negative pressure wound therapy, have emerged as adjunctive therapies for ulcers. Future treatment strategies include stem cell-based therapies, delivery of gene encoding growth factors, application of angiotensin receptors analogs and neuropeptides like substance P, as well as inhibition of inflammatory cytokines. This review provides an outlook of the pathophysiology in diabetic wound healing and summarizes the established and adjunctive treatment strategies, as well as the future therapeutic options for the treatment of DFUs.
C1 [Baltzis, Dimitrios; Eleftheriadou, Ioanna] Joslin Beth Israel Deaconess Foot Ctr & Microcirc, Boston, MA USA.
   [Veves, Aristidis] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA.
C3 Harvard University; Harvard University Medical Affiliates; Beth Israel
   Deaconess Medical Center; Harvard University; Harvard University Medical
   Affiliates; Beth Israel Deaconess Medical Center
RP Veves, A (通讯作者)，Beth Israel Deaconess Med Ctr, One Deaconess Rd,PA-321A, Boston, MA 02215 USA.
EM aveves@bidmc.harvard.edu
OI Veves, Aristidis/0000-0002-3901-4405; Eleftheriadou,
   Ioanna/0000-0003-2763-2481
FU National Institute of Health [1R01DK091949, 1R01NS066205, 1R01DK076937,
   1R01NS046710, 1R24DK091210-01]
FX Sponsorship for this study was funded by the National Institute of
   Health Grants 1R01DK091949 (AV), 1R01NS066205 (AV, LPN) 1R01DK076937
   (AV), 1R01NS046710 (AV) and 1R24DK091210-01 (AV). All named authors meet
   the ICMJE criteria for authorship for this manuscript, take
   responsibility for the integrity of the work as a whole, and have given
   final approval for the version to be published.
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NR 91
TC 587
Z9 672
U1 7
U2 491
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0741-238X
EI 1865-8652
J9 ADV THER
JI Adv. Ther.
PD AUG
PY 2014
VL 31
IS 8
BP 817
EP 836
DI 10.1007/s12325-014-0140-x
PG 20
WC Medicine, Research & Experimental; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Pharmacology & Pharmacy
GA AO5ZO
UT WOS:000341426600004
PM 25069580
DA 2026-07-24
ER

PT J
AU Matar, DY
   Ng, B
   Darwish, O
   Wu, MF
   Orgill, DP
   Panayi, AC
AF Matar, Dany Y.
   Ng, Brian
   Darwish, Oliver
   Wu, Mengfan
   Orgill, Dennis P.
   Panayi, Adriana C.
TI Skin Inflammation with a Focus on Wound Healing
SO ADVANCES IN WOUND CARE
LA English
DT Article
DE wound healing; inflammation; negative pressure wound therapy; diabetic
   wound; chronic wound; tissue regeneration
ID GENE-RELATED PEPTIDE; TOXIC EPIDERMAL NECROLYSIS; STEVENS-JOHNSON
   SYNDROME; VACUUM-ASSISTED CLOSURE; NECROSIS-FACTOR-ALPHA; SUBSTANCE-P;
   DENDRITIC CELLS; HIDRADENITIS SUPPURATIVA; PYODERMA-GANGRENOSUM; IN-VIVO
AB Significance: The skin is the crucial first-line barrier against foreign pathogens. Compromise of this barrier presents in the context of inflammatory skin conditions and in chronic wounds. Skin conditions arising from dysfunctional inflammatory pathways severely compromise the quality of life of patients and have a high economic impact on the U.S. health care system. The development of a thorough understanding of the mechanisms that can disrupt skin inflammation is imperative to successfully modulate this inflammation with therapies.Recent Advances: Many advances in the understanding of skin inflammation have occurred during the past decade, including the development of multiple new pharmaceuticals. Mechanical force application has been greatly advanced clinically. Bioscaffolds also promote healing, while reducing scarring.Critical Issues: Various skin inflammatory conditions provide a framework for analysis of our understanding of the phases of successful wound healing. The large burden of chronic wounds on our society continues to focus attention on the chronic inflammatory state induced in many of these skin conditions.Future Directions: Better preclinical models of disease states such as chronic wounds, coupled with enhanced diagnostic abilities of human skin, will allow a better understanding of the mechanism of action. This will lead to improved treatments with biologics and other modalities such as the strategic application of mechanical forces and scaffolds, which ultimately results in better outcomes for our patients.
C1 [Matar, Dany Y.; Ng, Brian; Darwish, Oliver; Wu, Mengfan; Orgill, Dennis P.; Panayi, Adriana C.] Brigham & Womens Hosp, Dept Surg, Div Plast Surg, Boston, MA USA.
   [Matar, Dany Y.] Washington Univ St Louis, Dept Biol, St Louis, MO USA.
   [Ng, Brian] St Louis Univ, Dept Med, Sch Med, St Louis, MO USA.
   [Darwish, Oliver] Calif Northstate Univ, Dept Med, Coll Med, Elk Grove, CA USA.
   [Wu, Mengfan] Peking Univ, Dept Plast Surg, Shenzhen Hosp, Shenzhen, Peoples R China.
   [Orgill, Dennis P.; Panayi, Adriana C.] Brigham & WomensHospital & Harvard Med Sch, Dept Surg, Div Plast Surg, 75 FrancisStreet, Boston, MA 02115 USA.
   [Matar, Dany Y.; Ng, Brian; Darwish, Oliver; Wu, Mengfan; Orgill, Dennis P.; Panayi, Adriana C.] Harvard Med Sch, Boston, MA USA.
   [Orgill, Dennis P.; Panayi, Adriana C.] Harvard Med Sch, 75 Francis St, Boston, MA 02115 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Washington University (WUSTL); Saint Louis University;
   Peking University; Harvard University; Harvard Medical School; Harvard
   University; Harvard Medical School
RP Orgill, DP; Panayi, AC (通讯作者)，Brigham & WomensHospital & Harvard Med Sch, Dept Surg, Div Plast Surg, 75 FrancisStreet, Boston, MA 02115 USA.; Orgill, DP; Panayi, AC (通讯作者)，Harvard Med Sch, Boston, MA USA.; Orgill, DP; Panayi, AC (通讯作者)，Harvard Med Sch, 75 Francis St, Boston, MA 02115 USA.
EM dorgill@bwh.harvard.edu; apanayi@bwh.harvard.edu
RI ; Panayi, Adriana/HHT-0513-2022; Orgill, Dennis/H-7596-2019
OI Matar, Dany/0000-0001-7108-0413; Panayi, Adriana/0000-0003-4053-9855;
   Wu, Mengfan/0000-0003-2646-3372; Orgill, Dennis/0000-0002-8279-7310
FU The Gillian Reny Stepping Strong Center for Trauma Innovation
   [T35HL110843]; NIH; National Heart Lung and Blood Institute
   [T35HL110843] Funding Source: NIH RePORTER
FX This work was funded by The Gillian Reny Stepping Strong Center for
   Trauma Innovation and is in part supported by NIH T35HL110843 fellowship
   to Brian Ng.
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NR 193
TC 56
Z9 61
U1 4
U2 63
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD MAY 1
PY 2023
VL 12
IS 5
BP 269
EP 287
DI 10.1089/wound.2021.0126
EA MAY 2022
PG 19
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 9D8GO
UT WOS:000802665800001
PM 35287486
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Glass, GE
   Murphy, GF
   Esmaeili, A
   Lai, LM
   Nanchahal, J
AF Glass, G. E.
   Murphy, G. F.
   Esmaeili, A.
   Lai, L. -M.
   Nanchahal, J.
TI Systematic review of molecular mechanism of action of negative-pressure
   wound therapy
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; ENDOTHELIAL GROWTH-FACTOR; MATRIX
   METALLOPROTEINASES; GENE-EXPRESSION; SHEAR-STRESS; TNF-ALPHA; EGR-1;
   HYPOXIA; INTERLEUKIN-8; TRANSCRIPTION
AB BackgroundNegative-pressure wound therapy (NPWT) promotes angiogenesis and granulation, in part by strain-induced production of growth factors and cytokines. As their expression profiles are being unravelled, it is pertinent to consider the mode of action of NPWT at the molecular level.
   MethodsMEDLINE (January 1997 to present), Embase (January 1997 to present), PubMed (no time limit), the Cochrane Database of Systematic Reviews and the Cochrane Controlled Trials Register were searched for articles that evaluated the influence of NPWT on growth factor expression quantitatively.
   ResultsSixteen studies met the inclusion criteria. Tumour necrosis factor expression was reduced in acute and chronic wounds, whereas expression of interleukin (IL) 1 was reduced in acute wounds only. Systemic IL-10 and local IL-8 expression were increased by NPWT. Expression of vascular endothelial growth factor, fibroblast growth factor 2, transforming growth factor and platelet-derived growth factor was increased, consistent with mechanoreceptor and chemoreceptor transduction in response to stress and hypoxia. Matrix metalloproteinase-1, -2, -9 and -13 expression was reduced but there was no effect on their enzymatic inhibitor, tissue inhibitor of metalloproteinase 1.
   ConclusionCytokine and growth factor expression profiles under NPWT suggest that promotion of wound healing occurs by modulation of cytokines to an anti-inflammatory profile, and mechanoreceptor and chemoreceptor-mediated cell signalling, culminating in angiogenesis, extracellular matrix remodelling and deposition of granulation tissue. This provides a molecular basis for understanding NPWT.
   How the vacuum works
C1 [Glass, G. E.; Nanchahal, J.] Univ Oxford, Kennedy Inst Rheumatol, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford OX3 7FY, England.
   [Murphy, G. F.] Univ Oxford, St Hughs Coll, Oxford OX3 7FY, England.
   [Glass, G. E.; Murphy, G. F.; Esmaeili, A.] Royal Free Hosp, Dept Plast Surg, London NW3 2QG, England.
   [Lai, L. -M.] Royal Free Hosp, Dept Gen & Breast Surg, London NW3 2QG, England.
   [Lai, L. -M.] St Albans Hosp, Dept Gen Surg, St Albans, Herts, England.
C3 University of Oxford; Kennedy Institute for Rheumatology; University of
   Oxford; University of London; University College London; UCL Medical
   School; Royal Free London NHS Foundation Trust; University of London;
   University College London; UCL Medical School; Royal Free London NHS
   Foundation Trust
RP Glass, GE (通讯作者)，Univ Oxford, Kennedy Inst Rheumatol, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Roosevelt Dr, Oxford OX3 7FY, England.
EM graeme.glass@ndorms.ox.ac.uk
RI ; Glass, Graeme/I-7011-2019
OI Esmaeili, Ali/0009-0003-5280-2574; Nanchahal,
   Jagdeep/0000-0002-9579-9411
FU Academy of Medical Sciences (AMS) [AMS-SGCL6-Glass] Funding Source:
   researchfish
CR [Anonymous], 2005, Zhongguo Linchuang Kangfu
   [Anonymous], 2004, Zhongguo Linchuang Kangfu
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NR 60
TC 176
Z9 214
U1 0
U2 37
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD DEC
PY 2014
VL 101
IS 13
BP 1627
EP 1636
DI 10.1002/bjs.9636
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AT2WI
UT WOS:000344794500002
PM 25294112
OA Bronze
DA 2026-07-24
ER

PT J
AU Ovaska, M
AF Ovaska, Mikko
TI Complications in ankle fracture surgery
SO ACTA ORTHOPAEDICA
LA English
DT Article
ID SURGICAL-SITE INFECTION; PRESSURE WOUND THERAPY; VACUUM-ASSISTED
   CLOSURE; LOWER-EXTREMITY TRAUMA; OF-THE-LITERATURE; DISTAL TIBIOFIBULAR
   SYNDESMOSIS; SOFT-TISSUE COMPLICATIONS; BREVIS MUSCLE FLAP; POSTERIOR
   MALLEOLAR FRACTURES; SUPERFICIAL PERONEAL NERVE
C1 Univ Helsinki, Cent Hosp, Dept Orthopaed Surg & Traumatol, Helsinki Bone & Joint Res Grp, Helsinki, Finland.
C3 University of Helsinki; Helsinki University Central Hospital
RP Ovaska, M (通讯作者)，Univ Helsinki, Cent Hosp, Dept Orthopaed Surg & Traumatol, Helsinki Bone & Joint Res Grp, Helsinki, Finland.
FU Research Foundation for Orthopaedics and Traumatology in Finland; Emil
   Aaltonen Foundation; Orion-Farmos Research Foundation; Duodecim
   Foundation; Helsinki University Central Hospital (EVO-grant)
FX This work was financially supported by The Research Foundation for
   Orthopaedics and Traumatology in Finland, The Emil Aaltonen Foundation,
   The Orion-Farmos Research Foundation, The Duodecim Foundation, and
   Helsinki University Central Hospital (EVO-grant).
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NR 256
TC 35
Z9 45
U1 0
U2 17
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND
SN 1745-3674
EI 1745-3682
J9 ACTA ORTHOP
JI Acta Orthop.
PD FEB
PY 2015
VL 86
SU 358
BP 2
EP 35
DI 10.3109/17453674.2014.1002273
PG 34
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA AZ3JL
UT WOS:000348123300001
PM 25586467
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Mutafchiyski, VM
   Popivanov, GI
   Kjossev, KT
   Chipeva, S
AF Mutafchiyski, Ventsislav M.
   Popivanov, G. I.
   Kjossev, K. T.
   Chipeva, S.
TI Open abdomen and VAC® in severe diffuse peritonitis
SO JOURNAL OF THE ROYAL ARMY MEDICAL CORPS
LA English
DT Article
DE SURGERY; WOUND MANAGEMENT
ID ASSISTED FASCIAL CLOSURE; MANAGEMENT; SYSTEMS
AB Background Currently, the open abdomen technique is the widely recognised method for treatment of life-threatening trauma, intra-abdominal sepsis, abdominal compartment syndrome and wound dehiscence. The techniques for temporary closure using negative pressure have gained increasing popularity. Although negative pressure wound therapy has been proved as an effective method in trauma, the results in diffuse peritonitis are contradictory.
   Methods Overall, 108 patients with diffuse peritonitis and open abdomen were prospectively enrolled from January 2006 to December 2013-69 treated with mesh-foil laparostomy without negative pressure and 49 with vacuum-assisted closure (VAC (R)) The primary endpoints were the rate of primary fascial closure and mortality. The secondary outcomes were the rate of complications-enteroatmospheric fistulas, intra-abdominal abscesses, wound infection and necrotising fasciitis, intensive care unit (ICU) and overall hospital stay.
   Results VAC was associated with higher overall (73% vs 53%) and late primary fascial closure rates (31% vs 7%), lower rates of necrotising fasciitis (2% vs 15%, p=0.012), intra-abdominal abscesses (10% vs 20%), enteroatmospheric fistulas (8% vs 19%), overall mortality (31% vs 53%, p<0.05), shorter ICU (6.1 vs 10.6days, p=0.002) and hospital stay (15.1 vs 25.9days, p=0.000).
   Conclusions The results clearly suggest the obvious advantage of VAC in comparison to the temporary abdominal closure without negative pressure in the cases with severe diffuse peritonitis. However, to a large extent, our results might be attributed to the combination of VAC with dynamic fascial closure.
C1 [Mutafchiyski, Ventsislav M.] Mil Med Acad, Dept Mil Surg, Clin Endoscop Endocrine Surg & Coloproctol, Sofia 1606, Bulgaria.
   [Popivanov, G. I.] Mil Med Acad, Clin Endoscop Endocrine Surg & Coloproctol, Sofia 1606, Bulgaria.
   [Kjossev, K. T.] Mil Med Acad, Clin Abdominal Surg, Sofia 1606, Bulgaria.
   [Chipeva, S.] Univ Natl & World Econ, Dept Stat & Econometr, Sofia, Bulgaria.
C3 Military Medical Academy Sofia; Military Medical Academy Sofia; Military
   Medical Academy Sofia; University of National & World Economics -
   Bulgaria
RP Popivanov, GI (通讯作者)，Mil Med Acad, 3 Georgi Sofijski Str, Sofia 1606, Bulgaria.
EM gerasimpopivanov@rocketmail.com
RI Popivanov, Georgi/IVH-4670-2023; Kjossev, Kirien/KQV-3036-2024
CR [Anonymous], 2000, ACTA CHIRURG AUSTRIA
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NR 25
TC 24
Z9 31
U1 0
U2 6
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 0035-8665
EI 2052-0468
J9 J ROY ARMY MED CORPS
JI J. R. Army Med. Corps
PD FEB
PY 2016
VL 162
IS 1
BP 30
EP 34
DI 10.1136/jramc-2014-000386
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA DD6BV
UT WOS:000370009600007
PM 25712560
DA 2026-07-24
ER

PT J
AU Zoeller, C
   Yoshizawa, E
   Sethi, MV
   Ure, BM
   Kuebler, JF
AF Zoeller, Christoph
   Yoshizawa, Emi
   Sethi, Mohammad V.
   Ure, Benno M.
   Kuebler, Joachim F.
TI Negative Pressure Wound Dressing Reduces Surgical Site Infections in
   Infants after Closed Abdominal Procedures: A Preliminary Report
SO EUROPEAN JOURNAL OF PEDIATRIC SURGERY
LA English
DT Article
DE negative pressure wound dressing; surgical site infection;
   clean-contaminated; contaminated; dirty abdominal procedure; infants
ID VACUUM-ASSISTED CLOSURE; THERAPY; INCISION; LAPAROTOMY; SURGERY;
   COMPLICATIONS; MECHANISMS; PREVENTION; COST
AB Introduction Negative pressure wound therapy (NPWT) is a novel tool to reduce surgical site infections (SSIs). Although SSIs are a common source of morbidity in infants undergoing laparotomy, the cost of the available NPWT devices has restricted its use to adult high-risk patients. We developed a low-cost method of NPWT in infants and analyzed its impact on the incidence of SSIs in infant patients.
   Materials and Methods A consecutive series of infants (age <= 12 months) who underwent a clean-contaminated, contaminated, or dirty abdominal procedure via laparotomy from 08/2015 to 12/2016 were included. The choice of the applied dressing, either NPWT or standard surgical dressing (SSD), was made at the surgeon's discretion. SSIs were documented prospectively. The Horan definition and the Clavien-Dindo classification were used. The cost of material was calculated for both groups.
   Results Ninety-three consecutive patients were included (65 SSD and 28 NPWT). SSI occurred in 10 patients in the SSD group, Grade I in 7 and Grade II in 3 (Clavien-Dindo classification). No SSI occurred in patients with NPWT (p < 0.05). The cost of an SSD was less than 1 (sic), and the cost of a NPWT was less than 10 (sic).
   Conclusion The routine use of this modified vacuum wound dressing may be an efficient and affordable technique to decrease SSIs in infants who underwent contaminated abdominal operations.
C1 [Zoeller, Christoph; Yoshizawa, Emi; Sethi, Mohammad V.; Ure, Benno M.; Kuebler, Joachim F.] Hannover Med Sch, Dept Pediat Surg, Carl Neuberg Str 1, D-30625 Hannover, Germany.
C3 Hannover Medical School
RP Zoeller, C (通讯作者)，Hannover Med Sch, Dept Pediat Surg, Carl Neuberg Str 1, D-30625 Hannover, Germany.
EM zoeller.christoph@mh-hannover.de
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NR 24
TC 5
Z9 6
U1 0
U2 2
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0939-7248
EI 1439-359X
J9 EUR J PEDIATR SURG
JI Eur. J. Pediatr. Surg.
PD AUG
PY 2019
VL 29
IS 4
BP 384
EP 387
DI 10.1055/s-0038-1660448
PG 4
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA JD1LS
UT WOS:000489736800011
PM 29920637
DA 2026-07-24
ER

PT J
AU Nordmyr, J
   Svensson, S
   Björck, M
   Acosta, S
AF Nordmyr, J.
   Svensson, S.
   Bjorck, M.
   Acosta, S.
TI Vacuum assisted wound closure in patients with lower extremity arterial
   disease
SO INTERNATIONAL ANGIOLOGY
LA English
DT Article
DE Negative-pressure wound therapy; Wound healing; Arterial occlusive
   diseases; Amputation, mortality
ID INFECTION; THERAPY; FOOT; PRESERVATION
AB Aim. The purpose of this investigation was to analyze predictors for wound healing, amputation and mortality after vacuum assisted closure (VAC (R)) therapy of wounds in the lower limb in patients with arterial disease.
   Methods. One hundred and twenty one wounds were treated and followed for 12 months at two vascular centres in Uppsala and Malmo, Sweden. VAC (R) therapy was applied in the wound at a topical negative pressure of 125 mmHg.
   Results. Median age of the patients was 74 years and critical lower limb ischemia was present in 87% of the patients at admission. Intestinal flora was cultivated in 74% of the wounds. VAC (R) associated bleeding occurred in four patients. Complete wound healing was achieved in 66%. Deep groin infections were associated with synthetic graft infection (P<0.001), treatment outside hospital (P<0.001), faster healing (P<0.01) and lower amputation rate (P<0.005). Diabetes mellitus (OR 2.7; [95% CI 1.2-6.2]) and foot wound (OR 3.0; (95% CI 1.2-7.4]) were independent predictors for amputation. The absence of complete wound healing was the strongest factor for both amputation (P<0.001) and death (P<0.001).
   Conclusion. VAC (R) therapy of complex wounds in the lower limbs in patients with vascular disease was associated with high healing rates. Non-healed wounds after VAC (R) therapy were predictors for amputation and death. [Int Angiol 2009;28:26-3 1]
C1 [Svensson, S.; Acosta, S.] Malmo Univ Hosp, Vasc Ctr, S-20502 Malmo, Sweden.
   [Nordmyr, J.; Bjorck, M.] Univ Uppsala Hosp, Inst Surg Sci, Vasc Surg Sect, Uppsala, Sweden.
   [Nordmyr, J.] Norrkoping Cty Hosp, Dept Surg, Norrkoping, Sweden.
C3 Lund University; Skane University Hospital; Uppsala University; Uppsala
   University Hospital
RP Acosta, S (通讯作者)，Malmo Univ Hosp, Vasc Ctr, S-20502 Malmo, Sweden.
EM stefan.acosta@telia.com
RI Acosta, Stefan/JAX-3225-2023; Acosta, Stefan/JAX-3225-2023
OI Acosta, Stefan/0000-0002-3225-0798; Acosta, Stefan/0000-0002-8895-6001
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 18
TC 13
Z9 14
U1 0
U2 2
PU EDIZIONI MINERVA MEDICA
PI TURIN
PA CORSO BRAMANTE 83-85 INT JOURNALS DEPT., 10126 TURIN, ITALY
SN 0392-9590
EI 1827-1839
J9 INT ANGIOL
JI Int. Angiol.
PD FEB
PY 2009
VL 28
IS 1
BP 26
EP 31
PG 6
WC Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA 448HU
UT WOS:000266254500005
PM 19190552
DA 2026-07-24
ER

PT J
AU Keshvari, A
   Mollamohammadi, L
   Keramati, MR
   Behboudi, B
   Fazeli, MS
   Kazemeini, A
   Naseri, A
   Shahmohammadi, E
   Foroutani, L
   Ayati, A
   Tayebi, A
   Sajjadian, Z
   Hadizadeh, A
   Ahmadi-Tafti, SM
AF Keshvari, Amir
   Mollamohammadi, Leila
   Keramati, Mohammad Reza
   Behboudi, Behnam
   Fazeli, Mohammad Sadegh
   Kazemeini, Alireza
   Naseri, Amirhossein
   Shahmohammadi, Elnaz
   Foroutani, Laleh
   Ayati, Aryan
   Tayebi, Amirhossein
   Sajjadian, Zahra
   Hadizadeh, Alireza
   Ahmadi-Tafti, Seyed-Mohsen
TI Pirfenidone in fibrotic hypersensitivity pneumonitis: a double-blind,
   randomised clinical trial of efficacy and safety
SO UPDATES IN SURGERY
LA English
DT Article
DE Colorectal Cancer; Anastomotic leakage; Negative-pressure wound therapy;
   Colon surgery; Endoscopic treatment; Endo-sponge
ID LOW ANTERIOR RESECTION; RECTAL-CANCER; ENDO-SPONGE; ANASTOMOTIC LEAKAGE;
   COMPLICATIONS; SURGERY; MANAGEMENT; THERAPY; COLON
AB Anastomotic leakage is one of the major complications of colorectal surgery, which might lead to reoperation, increased hospital stays, further intervention and mortality. Vacuum-assisted closure by devices such as Endo-SPONGE (R) produced by (B- Braun Medical B.V.) is currently being used to treat leakage and fistula. In this study, we aimed to assess the handmade vacuum-assisted sponge drain for anastomotic leakage following low anterior resection. This prospective study included 22 patients who had undergone sponge drain placement to treat anastomotic leakage. All patients had anastomotic leaks or defects after left anterior rectal resection (LAR) without ileostomy. They were treated with neo-adjuvant chemotherapy before the surgery and then subjected to rigid recto-sigmoidoscopy for 30 days following the operation. Any sign of leakage, such as perianal and pelvic pain, was immediately identified and followed up with a CT scan and another recto-sigmoidoscopy. Twenty-two patients were enrolled in this study, 12 men (54.5%) and 10 women (47.4%). All patients had received neoadjuvant chemotherapy with an average follow-up of 22.30 +/- 3.81. 75% of patients ( 15 cases) were successfully treated, and 17 patients (85%) underwent successful ostomy closure. Treatment failed in 5 patients (25%), including three men and two women. This study shows that handmade vacuum-assisted sponge drain is a cost-effective method of anastomotic leakage management with efficacy similar to that of Endo-SPONGE (R)
C1 [Keshvari, Amir; Mollamohammadi, Leila; Keramati, Mohammad Reza; Behboudi, Behnam; Fazeli, Mohammad Sadegh; Kazemeini, Alireza; Naseri, Amirhossein; Ahmadi-Tafti, Seyed-Mohsen] Univ Tehran Med Sci, Imam Hosp Complex, Colorectal Res Ctr, Tehran, Iran.
   [Keshvari, Amir; Mollamohammadi, Leila; Keramati, Mohammad Reza; Behboudi, Behnam; Fazeli, Mohammad Sadegh; Kazemeini, Alireza; Naseri, Amirhossein; Ahmadi-Tafti, Seyed-Mohsen] Univ Tehran Med Sci, Dept Surg, Div Colorectal Surg, Tehran 1419733141, Iran.
   [Shahmohammadi, Elnaz; Foroutani, Laleh; Ayati, Aryan; Tayebi, Amirhossein; Hadizadeh, Alireza] Univ Tehran Med Sci, Cardiovasc Res Inst, Res Ctr Adv Technol Cardiovasc Med, Tehran, Iran.
   [Sajjadian, Zahra] ACECR, Royan Inst Stem Cell Biol & Technol, Cell Sci Res Ctr, Dept Regenerat Med, Tehran, Iran.
C3 Tehran University of Medical Sciences; Tehran University of Medical
   Sciences; Tehran University of Medical Sciences; Academic Center for
   Education, Culture & Research (ACECR)
RP Ahmadi-Tafti, SM (通讯作者)，Univ Tehran Med Sci, Imam Hosp Complex, Colorectal Res Ctr, Tehran, Iran.; Ahmadi-Tafti, SM (通讯作者)，Univ Tehran Med Sci, Dept Surg, Div Colorectal Surg, Tehran 1419733141, Iran.; Hadizadeh, A (通讯作者)，Univ Tehran Med Sci, Cardiovasc Res Inst, Res Ctr Adv Technol Cardiovasc Med, Tehran, Iran.
EM ali1375hadi@gmail.com; smahmadit@sina.tums.ac.ir
RI hadizadeh, alireza/KHY-0892-2024; Ayati, Aryan/CAJ-1580-2022; Tayebi,
   Amirhossein/JRY-0103-2023; Keshvari, Amir/GYJ-0402-2022; Foroutani,
   Laleh/KPA-1877-2024; Keramati, Mohammad Reza/B-4144-2013; Ahmadi Tafti,
   Seyed Mohsen/AAS-4302-2020
OI hadizadeh, alireza/0000-0003-0821-7557; Ayati,
   Aryan/0000-0002-0241-6865; Foroutani, Laleh/0000-0002-2818-8477; Tayebi,
   Amirhossein/0000-0002-6327-7125; Naseri, Amirhosein/0000-0001-8548-1330;
   Ahmadi Tafti, Seyed Mohsen/0000-0002-3595-8353
CR [Anonymous], 2013, GE Port J Gastroenterol
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NR 32
TC 5
Z9 7
U1 0
U2 3
PU SPRINGER-VERLAG ITALIA SRL
PI MILAN
PA VIA DECEMBRIO, 28, MILAN, 20137, ITALY
SN 2038-131X
EI 2038-3312
J9 UPDATES SURG
JI Updates Surg.
PD JUN
PY 2023
VL 75
IS 4
BP 847
EP 854
DI 10.1007/s13304-023-01518-3
EA APR 2023
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA J4IH0
UT WOS:000976762900001
PM 37086350
DA 2026-07-24
ER

PT J
AU Magistri, P
   Olivieri, T
   Serra, V
   Tarantino, G
   Assirati, G
   Pecchi, A
   Ballarin, R
   Di Benedetto, F
AF Magistri, Paolo
   Olivieri, Tiziana
   Serra, Valentina
   Tarantino, Giuseppe
   Assirati, Giacomo
   Pecchi, Annarita
   Ballarin, Roberto
   Di Benedetto, Fabrizio
TI Vacuum-assisted management of surgical site infections after liver
   transplantation: 15-year experience in a tertiary hepatobiliary center
SO UPDATES IN SURGERY
LA English
DT Article
DE Wound healing; Vacuum therapy; Vacuum-assisted therapy; Vacuum-assisted
   closure; SSI; VAC
ID PRESSURE WOUND THERAPY; RISK-FACTORS; ASSOCIATION; RECIPIENTS; IMPACT
AB Immune compromised as well as critically ill patients are at higher risk of surgical wound infection and dehiscence. Wound infections critically influence the outcomes after liver transplantation. In particular, it was shown that they significantly reduce the overall survival rate when compared to patients with uneventful wound healing, and their occurrence is associated with death or graft loss within 1-year post-transplantation. From January 2001 through December 2017, 763 patients underwent liver transplantation in our Institution, the Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, "Policlinico" University Hospital, University of Modena and Reggio Emilia, Modena, Italy. We retrospectively analyzed data from our prospectively maintained database of patients treated with a negative pressure therapy device due to wound or abdominal infections. 13 patients underwent negative pressure treatments for surgical site infection after liver transplantation in our institution. Ten superficial "supra-fascial" applications (SF group) and three deeper abdominal (Ab group) were reported. Mean in-hospital stay for the SF group was 42.6 days, ranging from 8 to 80, while for the Ab group was 62 days (range 23-133), with an overall survival of 34 and 4.6 months, respectively. A multifactorial multidisciplinary approach is needed in the prevention of surgical site infections instead of mere antimicrobial prophylaxis The application of negative pressure wound therapy may help in controlling the diffusion of the infection and preventing sepsis.
C1 [Magistri, Paolo; Olivieri, Tiziana; Serra, Valentina; Tarantino, Giuseppe; Assirati, Giacomo; Ballarin, Roberto; Di Benedetto, Fabrizio] Univ Modena & Reggio Emilia, Hepatopancreatobiliary Surg Surg Oncol & Liver Tr, Via Pozzo 71, I-41124 Modena, MO, Italy.
   [Magistri, Paolo] Sapienza Univ Rome, Dept Med & Surg Sci & Translat Med, Rome, Italy.
   [Pecchi, Annarita] Univ Modena & Reggio Emilia, Dept Radiol, Modena, Italy.
C3 Universita di Modena e Reggio Emilia; Sapienza University Rome;
   Universita di Modena e Reggio Emilia
RP Di Benedetto, F (通讯作者)，Univ Modena & Reggio Emilia, Hepatopancreatobiliary Surg Surg Oncol & Liver Tr, Via Pozzo 71, I-41124 Modena, MO, Italy.
EM fabrizio.dibenedetto@unimore.it
RI Pecchi, Annarita/M-2559-2016; Tarantino, Giuseppe/AAD-1064-2022; Di
   Benedetto, Fabrizio/B-8388-2015; Magistri, Paolo/C-4425-2016
OI Pecchi, Annarita/0000-0001-8142-3256; Tarantino,
   Giuseppe/0000-0001-8102-6293; Di Benedetto,
   Fabrizio/0000-0002-6718-8760; Magistri, Paolo/0000-0001-8326-069X
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   Zanus G, 2011, TRANSPL INT, V24, pe23, DOI 10.1111/j.1432-2277.2010.01198.x
NR 20
TC 2
Z9 2
U1 0
U2 0
PU SPRINGER-VERLAG ITALIA SRL
PI MILAN
PA VIA DECEMBRIO, 28, MILAN, 20137, ITALY
SN 2038-131X
EI 2038-3312
J9 UPDATES SURG
JI Updates Surg.
PD SEP
PY 2019
VL 71
IS 3
BP 457
EP 462
DI 10.1007/s13304-018-0583-8
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA IO3AJ
UT WOS:000479252600008
PM 30143984
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Ernert, C
   Kielstein, H
   Azatyan, A
   Prantl, L
   Kehrer, A
AF Ernert, Carsten
   Kielstein, Heike
   Azatyan, Argine
   Prantl, Lukas
   Kehrer, Andreas
TI Extended arc of rotation of Latissimus Dorsi Musculocutaneous Flap
   providing well-vascularized tissue for reconstruction of complete
   defects of the sternum: An anatomical study of flap pedicle modification
SO CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
LA English
DT Article
DE Latissimus dorsi myocutaneous flap; deep sternal wound infection;
   circumflex scapular artery; microsurgery; single flap reconstruction;
   sternal reconstruction; sternal defect
ID VACUUM-ASSISTED CLOSURE; INFECTED MEDIAN STERNOTOMY; CHEST-WALL
   RECONSTRUCTION; RISK-FACTOR-ANALYSIS; WOUND INFECTIONS; MUSCLE FLAPS;
   CARDIAC-SURGERY; HEART-SURGERY; COMPLICATIONS; OSTEOMYELITIS
AB BACKGROUND: Deep sternal wound infections (DSWI) following cardiothoracic surgery represent a life quality endangering sequelae and may lead to sternal osteomyelitis. Radical debridement followed by Negative Pressure Wound Therapy (NPWT) may achieve infection control, provide angiogenesis, and improve respiratory function. When stable wound conditions have been established a sustainable plastic surgical flap reconstruction should be undertaken.
   OBJECTIVE: This study analyses a method to simplify defect coverage with a single Latissimus Dorsi Myocutaneous Flap (LDMF).
   METHODS: Preparation of 20 LDMF in ten fresh frozen cadavers was conducted. Surgical steps to increase pedicle length were evaluated. The common surgical preparation of LDMF was compared with additional transection of the Circumflex Scapular Artery (CSA).
   RESULTS: Alteration of the surgical preparation of LDMF by sacrificing the CSA may provide highly valuable wellvascularized muscle tissue above the sensitive area of the Xiphisternum. All defects could be completely reconstructed with a single LDMF. The gain in length of flap tissue in the inferior third of the sternum was 3.86 +/- 0.9 cm (range 2.2 to 8 cm).
   CONCLUSIONS: By sacrificing the CSA in harvesting the LDMF a promising gain in length, perfusion and volume may be achieved to cover big sternal defects with a single flap.
C1 [Ernert, Carsten] Ev Waldkrankenhaus Spandau, Dept Plast Hand & Microsurg, Berlin, Germany.
   [Kielstein, Heike] Martin Luther Univ Halle Wittenberg, Inst Anat, Halle, Germany.
   [Azatyan, Argine] Gorlitz Hosp, Dept Plast Reconstruct & Breast Surg, Gorlitz, Germany.
   [Prantl, Lukas; Kehrer, Andreas] Univ Med Ctr, Dept Plast & Reconstruct Surg, Regensburg, Germany.
   [Kehrer, Andreas] Ingolstadt Hosp, Div Hand & Plast Surg, Ingolstadt, Germany.
C3 Martin Luther University Halle Wittenberg; University of Regensburg
RP Ernert, C (通讯作者)，Ev Waldkrankenhaus Spandau, Dept Plast Hand & Microsurg, Berlin, Germany.
EM carstenernert@aol.com
RI Prantl, Lukas/AAM-1848-2021; Kehrer, Andreas/AAC-2483-2021; Kielstein,
   Heike/GNW-4839-2022
OI Kehrer, Andreas/0000-0001-9472-7662; 
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NR 67
TC 0
Z9 0
U1 0
U2 1
PU IOS PRESS
PI AMSTERDAM
PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS
SN 1386-0291
EI 1875-8622
J9 CLIN HEMORHEOL MICRO
JI Clin. Hemorheol. Microcirc.
PY 2024
VL 86
IS 1-2
BP 225
EP 236
DI 10.3233/CH-238115
PG 12
WC Hematology; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Hematology; Cardiovascular System & Cardiology
GA MK6X9
UT WOS:001193565600021
PM 37742631
OA Bronze
DA 2026-07-24
ER

PT J
AU Aslan-Horch, EC
   Horch, RE
   Arkudas, A
   Müller-Seubert, W
   Ludolph, I
AF Aslan-Horch, Emine Ceylan
   Horch, Raymund E.
   Arkudas, Andreas
   Mueller-Seubert, Wibke
   Ludolph, Ingo
TI Effects of Different Pressure Levels in Topical Negative Pressure
   Application-Analysis of Perfusion Parameters in a Clinical Skin Model
   Using Multimodal Imaging Techniques
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE negative pressure wound therapy; perfusion; pressure level; imaging;
   thermography; near infrared spectroscopy
ID VACUUM-ASSISTED CLOSURE; WOUND-THERAPY; BLOOD-FLOW; OXYGEN; GAUZE; WALL
AB The effects of topical negative pressure therapy (TNP) have been a subject of research for many years. In this study, we investigated new imaging devices to detect clinical changes that TNP causes on healthy tissue and identified differences in microcirculation created by different pressure levels. We used near-infrared spectroscopy (NIS), thermography, and a vein illuminator to measure the differences in oxygen saturation, tissue temperature, and vein pattern. A control group (-125 mmHg) and three comparison groups with only TNP dressing (Group 1), -25 mmHg (Group 2), and -175 mmHg (Group 3) were established. Thirty minutes of TNP on intact skin was followed by 30 min of resting. A total of 24 participants were measured by all imaging devices at predetermined time points. Oxygen saturation and skin temperature increased by 8.07% and 1.67 degrees C for the control group, 4.00% and 1.65 degrees C for Group 2, and 8.45% and 1.68 degrees C for Group 3. Group 1 showed a slight increase in oxygen saturation and a 2.7 degrees C increase in skin temperature. Over the 30 min following removal of TNP, oxygen saturation and temperature decreased gradually for all groups. The vein illuminator did not show significant differences in the venous pattern or flow. Our study showed that higher negative pressure values resulted in higher oxygen saturation and higher tissue temperature.
C1 [Ludolph, Ingo] Friedrich Alexander Univ Erlangen Nurnberg FAU, Univ Hosp Erlangen, Dept Plast & Hand Surg, Krankenhausstr 12, D-91054 Erlangen, Germany.
   Friedrich Alexander Univ Erlangen Nurnberg FAU, Univ Hosp Erlangen, Lab Tissue Engn & Regenerat Med, Krankenhausstr 12, D-91054 Erlangen, Germany.
C3 University of Erlangen Nuremberg; University of Erlangen Nuremberg
RP Ludolph, I (通讯作者)，Friedrich Alexander Univ Erlangen Nurnberg FAU, Univ Hosp Erlangen, Dept Plast & Hand Surg, Krankenhausstr 12, D-91054 Erlangen, Germany.
EM ingo.ludolph@uk-erlangen.de
RI Horch, Raymund E/H-8128-2019; Arkudas, Andreas/AAQ-6745-2021
OI Horch, Raymund E/0000-0002-6561-2353; Arkudas,
   Andreas/0000-0002-2473-5816; Ludolph, Ingo/0000-0003-4806-7717;
   Aslan-Horch, Emine Ceylan/0000-0001-7931-0439
CR Andres T, 2016, J FOOT ANKLE SURG, V55, P852, DOI 10.1053/j.jfas.2015.12.002
   Castilla DM, 2012, ADV WOUND CARE, V1, P225, DOI 10.1089/wound.2011.0319
   Geierlehner A, 2020, INT WOUND J, V17, P1496, DOI 10.1111/iwj.13428
   Horch R E, 2005, MMW Fortschr Med, V147 Suppl 1, P1
   Horch RE, 2020, EXPERT REV MED DEVIC, V17, P139, DOI 10.1080/17434440.2020.1714434
   Horch RE, 2018, ZBL CHIR, V143, P609, DOI 10.1055/a-0713-0517
   Horch RE, 2015, J WOUND CARE, V24, P21, DOI 10.12968/jowc.2015.24.Sup4b.21
   Hunter Judith E, 2007, Int Wound J, V4, P256, DOI 10.1111/j.1742-481X.2007.00361.x
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   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Yip WL, 2015, INT WOUND J, V12, P620, DOI 10.1111/iwj.12324
NR 30
TC 7
Z9 8
U1 0
U2 1
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD SEP
PY 2022
VL 11
IS 17
AR 5133
DI 10.3390/jcm11175133
PG 13
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 4J2NP
UT WOS:000851105800001
PM 36079063
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Innocenti, M
   Santini, M
   Dreassi, E
   Martin, R
   Melita, D
   Colombini, B
   Innocenti, A
AF Innocenti, Marco
   Santini, Mariella
   Dreassi, Emanuela
   Martin, Robin
   Melita, Dario
   Colombini, Barbara
   Innocenti, Alessandro
TI Effects of Cutaneous Negative Pressure Application on Perforator Artery
   Flow in Healthy Volunteers: A Preliminary Study
SO JOURNAL OF RECONSTRUCTIVE MICROSURGERY
LA English
DT Article
DE microsurgery; perforator flap; perforator; microsurgical procedures
ID VACUUM-ASSISTED CLOSURE; WOUND THERAPY; BLOOD-FLOW; ENDOTHELIAL-CELLS;
   FLAPS
AB Background The creation of skin flaps based on small perforator vessels is an increasingly popular procedure nowadays; the optimization of their blood supply enhances surgical success. This study evaluates the effects on the flowmetries of 7 days' negative pressure application on the skin surface overlying the muscle fascia emergence of periumbilical perforators of the deep inferior epigastric artery (DIEA).
   Methods Ten volunteer participants were enrolled. In each subject, one periumbilical perforator of the DIEA was identified on each side of the abdomen using an eco-color-Doppler. One of them was used as the control group, while the other (the study group) underwent 80mm Hg negative pressure for 7 days. The flowmetries of both perforators were measured before and after the application of negative pressure wound therapy.
   Results After the application of negative pressure, randomly applied on the skin surface over one of the two selected periumbilical perforators, an increase in the flowmetries was observed in both groups of perforators (2.74 cm/s; p <0.0001). The relative flowmetry increase in the control group was 9.55% (2.735 cm/s), while in the study group it was 44.03% (8.748 cm/s).
   Conclusion The application of negative pressure system on the skin surface over the muscle fascia emergence of the selected periumbilical perforators showed an increase in flowmetry. Although this is a preliminary study, this simple and economical procedure before surgery could be usefully employed to increase the rate of success in microsurgical procedures.
C1 [Innocenti, Marco; Melita, Dario; Innocenti, Alessandro] Careggi Univ Hosp, Dept Plast & Reconstruct Microsurg, Viale Giacomo Matteotti 42, I-50132 Florence, Italy.
   [Santini, Mariella] Careggi Univ Hosp, Dept Cardiovasc Diagnost, Florence, Italy.
   [Dreassi, Emanuela] Univ Florence, Dept Stat Informat Applicaz G Parenti DiSIA, Florence, Italy.
   [Martin, Robin] Sci Consulting, Foggathorpe, East Yorkshire, England.
   [Colombini, Barbara] Univ Florence, Sch Human Hlth Sci, Sect Physiol Sci, Dept Expt & Clin Med, Florence, Italy.
C3 University of Florence; Azienda Ospedaliero Universitaria Careggi;
   University of Florence; Azienda Ospedaliero Universitaria Careggi;
   University of Florence; University of Florence
RP Innocenti, A (通讯作者)，Careggi Univ Hosp, Dept Plast & Reconstruct Microsurg, Viale Giacomo Matteotti 42, I-50132 Florence, Italy.
EM innocentialessandro@alice.it
RI COLOMBINI, Barbara/AAG-3272-2020; innocenti, alessandro/KIC-1725-2024;
   Dreassi, Emanuela/B-5728-2012; Melita, Dario/OFO-1701-2025
OI COLOMBINI, Barbara/0000-0003-1397-9791; innocenti,
   alessandro/0000-0002-6959-4455; Martin, Robin/0000-0002-9314-0437;
   Dreassi, Emanuela/0000-0002-4863-1800; INNOCENTI,
   Marco/0000-0003-3533-1398; Melita, Dario/0000-0003-0560-800X
CR [Anonymous], 1835, LANCET
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NR 24
TC 5
Z9 6
U1 0
U2 1
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 0743-684X
EI 1098-8947
J9 J RECONSTR MICROSURG
JI J. Reconstr. Microsurg.
PD MAR
PY 2019
VL 35
IS 3
BP 189
EP 193
DI 10.1055/s-0038-1668157
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HO1AL
UT WOS:000460637500005
PM 30112753
DA 2026-07-24
ER

PT J
AU Nevitt, BN
   Adkesson, MJ
   Jankowski, G
   West, P
   Langan, JN
AF Nevitt, Benjamin N.
   Adkesson, Michael J.
   Jankowski, Gwen
   West, Paula
   Langan, Jennifer N.
TI Lumbar hemilaminectomy for treatment of diskospondylitis in an aardvark
   (Orycteropus afer)
SO JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION
LA English
DT Article
ID VACUUM-ASSISTED-CLOSURE; SPINAL DECOMPRESSION; OSTEOMYELITIS
AB CASE DESCRIPTION
   A 17-year-old sexually intact male aardvark (Orycteropus afer) was evaluated because of hind limb proprioception deficits and ataxia.
   CLINICAL FINDINGS
   Results of examination and CT suggested a diagnosis of intervertebral disk disease and diskospondylitis at the L2-3 intervertebral space. Magnetic resonance imaging of the vertebral column also indicated intervertebral disk rupture with spinal cord compression and inflammation of the adjacent epaxial musculature
   TREATMENT AND OUTCOME
   Hemilaminectomy was performed according to the technique described for dogs. Anatomic variations encountered intraoperatively limited the ability to completely remove the affected disk material; however, adequate decompression of the spinal cord was achieved. Microbial culture and susceptibility testing of surgical biopsy specimens yielded a multidrug-resistant Enterococcus faecalis that was treated with a 10-week course of linezolid. Intensive postoperative care required constant rate infusions for adequate sedation, analgesia, and antimicrobial treatment. Dehiscence of the surgical site occurred 3 weeks after surgery and was treated with negative pressure wound therapy. Physical rehabilitation initiated 5 days after surgery progressed from passive range of motion to the use of an underwater treadmill. Despite initial improvement, acute deterioration occurred 5.5 months after surgery. Repeated CT revealed progression of diskospondylitis, which prompted euthanasia.
   CLINICAL RELEVANCE
   Postoperative hind limb paresis and paralysis in this species presented considerable challenges for care and rehabilitation. Patient demeanor, size, and anatomy required development of custom mechanical devices. Despite the inability to eliminate the multidrug-resistant bacterial osteomyelitis that resulted in the death of this aardvark, information gained may benefit treatment of subsequent patients.
C1 [Nevitt, Benjamin N.; Adkesson, Michael J.; Langan, Jennifer N.] Brookfield Zoo, Chicago Zool Soc, 3300 Golf Rd, Brookfield, IL 60513 USA.
   [Jankowski, Gwen] Denver Zoo, 2300 Steele St, Denver, CO 80205 USA.
   [West, Paula] Vet Specialty Ctr, 1515 Busch Pkwy, Buffalo Grove, IL 60089 USA.
   [Langan, Jennifer N.] Univ Illinois, Dept Vet Clin Med, Coll Vet Med, Urbana, IL 61802 USA.
   [Nevitt, Benjamin N.] San Diego Zoo, 2920 Zoo Dr, San Diego, CA 92101 USA.
C3 University of Illinois System; University of Illinois Urbana-Champaign;
   Zoological Society of San Diego
RP Nevitt, BN (通讯作者)，Brookfield Zoo, Chicago Zool Soc, 3300 Golf Rd, Brookfield, IL 60513 USA.; Nevitt, BN (通讯作者)，San Diego Zoo, 2920 Zoo Dr, San Diego, CA 92101 USA.
EM bnevitt@sandiegozoo.org
OI Adkesson, Michael/0000-0002-8766-5296
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NR 21
TC 1
Z9 1
U1 0
U2 7
PU AMER VETERINARY MEDICAL ASSOC
PI SCHAUMBURG
PA 1931 N MEACHAM RD SUITE 100, SCHAUMBURG, IL 60173-4360 USA
SN 0003-1488
EI 1943-569X
J9 JAVMA-J AM VET MED A
JI JAVMA-J. Am. Vet. Med. Assoc.
PD FEB 15
PY 2018
VL 252
IS 4
BP 464
EP 472
PG 9
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA FU8JO
UT WOS:000424099400022
PM 29393738
DA 2026-07-24
ER

PT J
AU Mody, GN
   Mutabazi, V
   Zurovcik, DR
   Bitega, JP
   Nsanzimana, S
   Harward, SH
   Wagner, CM
   Nutt, CT
   Binagwaho, A
AF Mody, Gita N.
   Mutabazi, Vincent
   Zurovcik, Danielle R.
   Bitega, Jean Paul
   Nsanzimana, Sabin
   Harward, Sardis H.
   Wagner, Claire M.
   Nutt, Cameron T.
   Binagwaho, Agnes
TI Design, testing, and scale-up of medical devices for global health:
   negative pressure wound therapy and non-surgical male circumcision in
   Rwanda
SO GLOBALIZATION AND HEALTH
LA English
DT Editorial Material
ID RESOURCE-LIMITED SETTINGS; HIV PREVENTION; REVERSE INNOVATION; TRIAL;
   MEN; INFECTION; COUNTRIES; PROGRAM; SYSTEMS; FUTURE
C1 [Mody, Gita N.] Brigham & Womens Hosp, Ctr Surg & Publ Hlth, Dept Gen Surg, 75 Francis St, Boston, MA 02115 USA.
   [Mutabazi, Vincent; Nsanzimana, Sabin] Rwanda Biomed Ctr, Kigali, Rwanda.
   [Zurovcik, Danielle R.] Worldwide Innovat Healthcare WiCare, Cambridge, MA USA.
   [Bitega, Jean Paul] Minist Def Rwanda, Kigali, Rwanda.
   [Harward, Sardis H.] Dartmouth Ctr Hlth Care Delivery Sci, Hanover, NH USA.
   [Wagner, Claire M.] Global Hlth Delivery Partnership, Boston, MA USA.
   [Binagwaho, Agnes] Minist Hlth Rwanda, Kigali, Rwanda.
   [Binagwaho, Agnes] Harvard Univ, Sch Med, Boston, MA USA.
   [Binagwaho, Agnes] Geisel Sch Med Dartmouth, Hanover, NH USA.
   [Nutt, Cameron T.] Partners Hlth, Boston, MA USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Rwanda Biomedical Center; Dartmouth College; Harvard
   University; Harvard Medical School; Dartmouth College; Mass General
   Brigham
RP Mody, GN (通讯作者)，Brigham & Womens Hosp, Ctr Surg & Publ Hlth, Dept Gen Surg, 75 Francis St, Boston, MA 02115 USA.
EM gmody@partners.org
RI Mody, Gita/KQV-0468-2024
OI Mody, Gita/0000-0003-0218-6948
CR [Anonymous], 2014, LANCET, V383, P383, DOI 10.1016/S0140-6736(14)60134-3
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   World Health Organization, 2013, GUID US DEV AD MAL C
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NR 39
TC 7
Z9 8
U1 0
U2 8
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1744-8603
J9 GLOBALIZATION HEALTH
JI Global. Health
PD MAY 12
PY 2015
VL 11
AR 20
DI 10.1186/s12992-015-0101-4
PG 6
WC Public, Environmental & Occupational Health
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Public, Environmental & Occupational Health
GA CI9DV
UT WOS:000355071500002
PM 25963175
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ellenrieder, M
   Redanz, S
   Bader, R
   Mittelmeier, W
   Podbielski, A
AF Ellenrieder, Martin
   Redanz, Sylvio
   Bader, Rainer
   Mittelmeier, Wolfram
   Podbielski, Andreas
TI Influence of Antimicrobial Coatings of Vacuum-Assisted Closure Dressings
   on Methicillin-Resistant Staphylococcus aureus Growth Kinetics:
   An In Vitro Study
SO SURGICAL INFECTIONS
LA English
DT Article
ID NEGATIVE-PRESSURE; WOUND THERAPY; SILVER; ANTIBACTERIAL; PREVENTION;
   ULCERS; VIVO
AB Background: Silver-containing negative-pressure wound therapy (NPWT) foam dressings should reduce the microbial load of infected surgical sites and thereby promote healing. The effects of silver and an experimental copper coating of NPWT dressings on the growth kinetics of methicillin-resistant Staphylococcus aureus (MRSA) were investigated with a focus on the importance of the initial bacterial load and the incubation time.
   Methods: Commercially available foam samples with and without silver coating were inoculated in vitro with six MRSA suspensions differing in bacterial concentration (1.85x10(3) to 1.85x10(8) colony-forming units per milliliter [CFU/mL]). In a second series, uncoated, silver-containing and experimental copper-coated foam samples were inoculated with one MRSA suspension (1.85x10(6) CFU/mL). The MRSA viable counts in the entrapped fluid were evaluated statistically after 1, 3, 7, and 14 d incubation.
   Results: Silver foam samples reduced MRSA counts by two decimal powers compared with the corresponding inocula. With respect to the uncoated samples, silver coating reduced MRSA concentrations by up to 7 logs, which was significant (p <= 0.045) for all groups except the one with the highest MRSA concentration. The antibacterial effect of copper became apparent only after 7 d, but thereafter was far more pronounced than the effects of silver (p<0.01 after 14 d).
   Conclusions: Antimicrobial-coated foam dressings showed significant in vitro antibacterial properties and thus could be advantageous in the treatment of MRSA-infected incisions.
C1 [Ellenrieder, Martin; Bader, Rainer; Mittelmeier, Wolfram] Univ Med Rostock, Dept Orthopaed, D-18055 Rostock, Germany.
   [Redanz, Sylvio; Podbielski, Andreas] Univ Med Rostock, Inst Med Microbiol Virol & Hyg, D-18055 Rostock, Germany.
C3 University of Rostock; University of Rostock
RP Ellenrieder, M (通讯作者)，Univ Med Rostock, Dept Orthopaed, Doberaner Str 142, D-18055 Rostock, Germany.
EM martin.ellenrieder@uni-rostock.de
RI Redanz, Sylvio/AAH-1369-2020; Ellenrieder, Martin/JQJ-5155-2023
OI Redanz, Sylvio/0000-0003-1541-2545; 
CR [Anonymous], 2007, BUNDESGESUNDHEITSBLA, V50, P377, DOI 10.1007/s00103-007-0167-0
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NR 35
TC 9
Z9 10
U1 0
U2 9
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD APR 1
PY 2015
VL 16
IS 2
BP 139
EP 145
DI 10.1089/sur.2013.268
PG 7
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA CF2EN
UT WOS:000352360400004
PM 25658621
DA 2026-07-24
ER

PT J
AU Campisi, CC
   Boccardo, F
   Piazza, C
   Campisi, C
AF Campisi, Corrado C.
   Boccardo, Francesco
   Piazza, Cesare
   Campisi, Corradino
TI Evolution of chylous fistula management after neck dissection
SO CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY
LA English
DT Review
DE chyle leak; conservative management; lymphatic fistula; surgical
   options; thoracic duct
ID THORACIC-DUCT EMBOLIZATION; VACUUM-ASSISTED CLOSURE; PAPILLARY
   THYROID-CARCINOMA; PRESSURE WOUND THERAPY; POSTOPERATIVE COMPLICATIONS;
   PERCUTANEOUS EMBOLIZATION; CHYLOTHORAX; SOMATOSTATIN; LYMPHEDEMA;
   EXPERIENCE
AB Purpose of review
   The present review is focused on the management of lymphatic, chylous, and thoracic duct lesions following head and neck surgery, with particular attention to these complications after neck dissection. Postoperative scenarios may include chylous fistula, chylothorax, chylomediastinum, chylopericardium, lymphocele, persistent lymphorrhea, and secondary lymphedema.
   Recent findings
   There is a paucity of literature on the treatment of lymphatic, chylous, and thoracic duct injuries following head and neck surgery; however, this review suggests that the most appropriate treatment should include both conservative and surgical approaches. Nonsurgical options consist of low-fat diet with medium-chain triglycerides, total parenteral nutrition, careful monitoring of fluid and electrolytes, drainage of the leakage, somatostatin analogs such as octreotide, and negative-pressure wound therapy. On the other hand, surgical management includes therapeutic percutaneous lymphography-guided thoracic duct cannulation and embolization, thoracic duct ligation, excision and imbrication of leaking lymphatics, chylous fistula surgical/microsurgical repair, fistula closure by locoregional flaps, video-assisted thoracoscopic surgery, thoracotomy, pleurodesis and decortication, pericardial 'window', and pleura-venous/pleura-peritoneal shunts. In addition, single or, preferably, multiple lymphovenous anastomoses may be taken into account.
   Summary
   The various possible clinical presentations of such challenging lymphatic, chylous, and thoracic duct injuries require an appropriate multidisciplinary approach by experienced teams. Primary prevention of these complications can be achieved through adequate surgical planning to minimize lesions, including structured and thorough patient assessment, and centralization of resources and teams.
C1 [Campisi, Corrado C.] Univ Hosp San Martino, IRCCS, IST Natl Inst Canc Res, Dept Surg,Unit Plast & Reconstruct Surg, I-16132 Genoa, Italy.
   [Boccardo, Francesco; Campisi, Corradino] Univ Hosp San Martino, IRCCS, IST Natl Inst Canc Res, Dept Surg,Unit Lymphat Surg, I-16132 Genoa, Italy.
   [Piazza, Cesare] Univ Brescia, Dept Otorhinolaryngol Head & Neck Surg, Brescia, Italy.
C3 University of Genoa; IRCCS AOU San Martino IST; University of Genoa;
   IRCCS AOU San Martino IST; University of Brescia
RP Campisi, CC (通讯作者)，Univ Hosp San Martino, IRCCS, IST Natl Inst Canc Res, Dept Surg,Unit Plast & Reconstruct Surg, Largo Rosanna Benzi 10, I-16132 Genoa, Italy.
EM corrado.campisi@edu.unige.it
RI ; PIAZZA, Cesare/H-5925-2018; BOCCARDO, FRANCESCO MARIA/AAB-7086-2019
OI Campisi, Corrado/0000-0002-3565-8764; PIAZZA,
   Cesare/0000-0002-2391-9357; BOCCARDO, FRANCESCO
   MARIA/0000-0002-5369-6852; Campisi, Corrado/0000-0002-3565-8764
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NR 69
TC 71
Z9 95
U1 0
U2 15
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1068-9508
EI 1531-6998
J9 CURR OPIN OTOLARYNGO
JI Curr. Opin. Otolaryngol. Head Neck Surg.
PD APR
PY 2013
VL 21
IS 2
BP 150
EP 156
DI 10.1097/MOO.0b013e32835e9d97
PG 7
WC Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology
GA 105ZT
UT WOS:000316111900009
PM 23449286
DA 2026-07-24
ER

PT J
AU Kim, CW
   Kim, JS
   Lee, AH
   Kim, YS
AF Kim, Chai-Won
   Kim, Jeong-Soo
   Lee, Ae-Hee
   Kim, Yong-Seok
TI Viscum album extract (Helixor-M) treatment for thoracic duct
   injury after modified radical neck dissection: a case report
SO GLAND SURGERY
LA English
DT Article
DE Thoracic duct injury; radical neck dissection; chyle leakage; Viscum
   album; Helixor-M
ID CHEMICAL PLEURODESIS; LEAKAGE; CHYLOTHORAX; MANAGEMENT
AB Chyle leakage after modified radical neck dissection is a rare condition that could be occasionally life-threatening if untreated. We report the first case of successful management of a thoracic duct injury using Viscum album extract (Helixor-M). A 54-year-old woman diagnosed with papillary thyroid cancer of the right lobe of the thyroid with metastasis to cervical lymph node levels II-VI, bilaterally, underwent total thyroidectomy and modified radical neck dissection. Three days postoperatively, the surgical team identified a thoracic duct injury due to drainage of chyle from the Jackson-Pratt drain inserted in the right side of the patient's neck. Various medical treatments (octreotide, withdrawal of enteral feeding, and total parenteral nutrition) and surgical treatments [lymphatic ligation of cervical lymph node level IV and negative pressure wound therapy (vacuum-assisted closure)] were performed, but the drainage persisted. Viscum album extract (Helixor-M) was then injected through the drain. The dose of Viscum album extract was increased while being cautious of its adverse effects, such as nausea, vomiting, erythema, induration at the injection site, and flu-like symptoms. The injection was effective in stopping the drainage and the patient's condition improved, without recurrence. The patient was discharged on the 64th postoperative day without any further complications. Our results suggest that treatment of thoracic duct injury after neck surgery with Viscum album extract (Helixor-M) may be a novel, less invasive alternative approach to treat cases resistant to standard treatments.
C1 [Kim, Chai-Won; Kim, Yong-Seok] Catholic Univ Korea, Coll Med, Uijeongbu St Marys Hosp, Dept Surg, 271 Cheonbo Ro, Uijeongbu Si 11765, Gyenggi Do, South Korea.
   [Kim, Jeong-Soo] Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Dept Surg, 222 Banpo Daero, Seoul, South Korea.
   [Lee, Ae-Hee] Catholic Univ Korea, Coll Med, Uijeongbu St Marys Hosp, Gen Surg Unit, 271 Cheonbo Ro, Uijeongbu Si, Gyenggi Do, South Korea.
C3 Catholic University of Korea; Catholic University of Korea; Seoul St.
   Mary's Hospital; Catholic University of Korea
RP Kim, YS (通讯作者)，Catholic Univ Korea, Coll Med, Uijeongbu St Marys Hosp, Dept Surg, 271 Cheonbo Ro, Uijeongbu Si 11765, Gyenggi Do, South Korea.
EM dydtjr97@catholic.ac.kr
CR Ahn D, 2015, ANN SURG ONCOL, V22, pS1000, DOI 10.1245/s10434-015-4822-7
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NR 19
TC 4
Z9 5
U1 0
U2 5
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2227-684X
EI 2227-8575
J9 GLAND SURG
JI Gland Surg.
PD FEB
PY 2021
VL 10
IS 2
BP 832
EP 836
DI 10.21037/gs-20-629
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA QN5DD
UT WOS:000622479000032
PM 33708565
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Nickl, S
   Steindl, J
   Langthaler, D
   Nierlich-Hold, A
   Pona, I
   Hitzl, W
   Kocher, A
   Happak, W
   Radtke, C
   Tzou, CH
AF Nickl, Stefanie
   Steindl, Johannes
   Langthaler, Daniel
   Nierlich-Hold, Alina
   Pona, Igor
   Hitzl, Wolfgang
   Kocher, Alfred
   Happak, Wolfgang
   Radtke, Christine
   Tzou, Chieh-Han
TI First Experiences with Incisional Negative Pressure Wound Therapy in a
   High-Risk Poststernotomy Patient Population treated with Pectoralis
   Major Muscle Flap for Deep Sternal Wound Infection
SO JOURNAL OF RECONSTRUCTIVE MICROSURGERY
LA English
DT Article
DE deep sternal wound infection; pectoralis major muscle flap; surgical
   incision management system
ID VACUUM-ASSISTED CLOSURE; MYOCUTANEOUS ADVANCEMENT FLAPS;
   OPEN-HEART-SURGERY; MEDIAN STERNOTOMY; CARDIAC-SURGERY; SURGICAL
   INCISIONS; MANAGEMENT-SYSTEM; COMPLICATIONS; MEDIASTINITIS;
   RECONSTRUCTION
AB Background Radical debridement and wound closure with vascularized flaps has become a standard procedure in the treatment of deep sternal wound infections. Negative pressure incision management systems have been proven to diminish wound infections after sternotomy. In this study, the utility of Prevena Incision Management System (KCI Licensing Inc.) was evaluated in obese patients who received unilateral pectoralis major flap for the treatment of deep sternal wound infections.
   Methods The outcome and wound-related complication rates of 19 obese patients (mean body mass index, 33.7) treated for deep sternal wound infection with pectoralis major muscle flap in combination with Prevena between 2011 and 2016 were compared with 28 obese patients treated with conventional wound dressing only between 2000 and 2010.
   Results In patients additionally treated with Prevena, significantly fewer surgical revisions due to wound-related complications were necessary as compared with patients who received conventional wound dressing (5.3 vs. 32.1%, p =0.034). A significantly shorter ICU length of stay (median 0 vs. 3.5 days, p <0.001) and a trend toward shorter length of hospitalization (median 14 vs. 19.5 days after pectoralis major flap) could be observed.
   Conclusion The application of Prevena significantly reduced revision surgery rates in obese patients treated with unilateral pectoralis major flap for deep sternal wound infections.
C1 [Nickl, Stefanie; Langthaler, Daniel; Nierlich-Hold, Alina; Pona, Igor; Happak, Wolfgang; Radtke, Christine; Tzou, Chieh-Han] Med Univ Vienna, Div Plast & Reconstruct Surg, Dept Surg, Vienna, Austria.
   [Steindl, Johannes] Paracelsus Med Unvers, Dept Cardiac Surg, Salzburg, Austria.
   [Hitzl, Wolfgang] Paracelsus Med Univ Salzburg, Res Off, Biostat, Salzburg, Austria.
   [Kocher, Alfred] Med Univ Vienna, Div Cardiac Surg, Dept Surg, Vienna, Austria.
C3 Medical University of Vienna; Paracelsus Private Medical University;
   Medical University of Vienna
RP Tzou, CH (通讯作者)，Med Univ Vienna, Div Plast & Reconstruct Surg, Dept Surg, Vienna Gen Hosp, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
EM chieh-han.tzou@meduniwien.ac.at
RI Kocher, Alfred/OIS-7365-2025; Radtke, Christine/M-2927-2013; Hitzl,
   Wolfgang/A-1068-2013; Tzou, Chieh-Han John/A-4897-2017; Steindl,
   Johannes/OAJ-5398-2025
OI Kocher, Alfred/0000-0002-2818-2227; Radtke,
   Christine/0000-0001-6877-5038; Hitzl, Wolfgang/0000-0002-7696-1479;
   Nickl, Stefanie/0000-0002-3762-4840; Tzou, Chieh-Han
   John/0000-0002-3903-801X; 
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NR 53
TC 19
Z9 24
U1 1
U2 4
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 0743-684X
EI 1098-8947
J9 J RECONSTR MICROSURG
JI J. Reconstr. Microsurg.
PD JAN
PY 2018
VL 34
IS 1
BP 1
EP 7
DI 10.1055/s-0037-1605379
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FS8EN
UT WOS:000422643300001
PM 28992646
DA 2026-07-24
ER

PT J
AU Nuutila, K
   Siltanen, A
   Peura, M
   Harjula, A
   Nieminen, T
   Vuola, J
   Kankuri, E
   Aarnio, P
AF Nuutila, Kristo
   Siltanen, Antti
   Peura, Matti
   Harjula, Ari
   Nieminen, Tapio
   Vuola, Jyrki
   Kankuri, Esko
   Aarnio, Pertti
TI Gene expression profiling of negative-pressure-treated skin graft donor
   site wounds
SO BURNS
LA English
DT Article
DE Wound healing; Gene expression; Epidermis; Dermis
ID VACUUM-ASSISTED CLOSURE; THERAPY
AB Negative-pressure wound therapy (NPWT) is Widely used to improve skin wound healing. Although NPWT has been studied as a treatment for wound closure and healing, the molecular mechanisms explaining its therapeutic effects remain unclear. To investigate the effect of NPWT on gene expression, and to discover the genes most dominantly responding to this treatment during skin wound healing, we applied negative pressure on split-thickness skin graft donor sites from the first postoperative day (POD) to the seventh POD. Biopsies were collected from 4 NPWT-treated and 2 control patients. Two biopsy samples were taken from each patient: one from intact skin before graft harvesting, and one on the seventh POD from the donor site wound. Genome-wide microarrays were performed on all samples. Gene expression changes on the seventh POD were compared between NPWT and control patients, and were analyzed for statistical significance. In addition, we analyzed wound exudates for volume, and for concentrations of leukocytes, erythrocytes, and haemoglobin. NPWT induced major changes in gene expression during healing. These changes ranged from 10-fold induction to 27-fold suppression. The genes most induced were associated with cell proliferation and inflammation, and the most down-regulated genes were linked to epidermal differentiation. Our results provide the first insight into the molecular mechanisms behind NPWT, and suggest that NPWT enhances specific inflammatory gene expression at the acute phase associated with epithelial migration and wound healing. However, its continued use may inhibit epithelial differentiation. (c) 2012 Elsevier Ltd and ISBI. All rights reserved.
C1 [Nuutila, Kristo; Siltanen, Antti; Peura, Matti; Harjula, Ari; Kankuri, Esko] Univ Helsinki, Inst Biomed, FIN-00290 Helsinki, Finland.
   [Harjula, Ari] Univ Helsinki, Meilahti Hosp, Dept Cardiothorac Surg, FIN-00290 Helsinki, Finland.
   [Nieminen, Tapio; Aarnio, Pertti] Satakunta Cent Hosp, Dept Surg, Pori 28500, Finland.
   [Vuola, Jyrki] Univ Helsinki, Cent Hosp, Toolo Hosp, Helsinki Burn Ctr, Helsinki 00260, Finland.
C3 University of Helsinki; University of Helsinki; Satakunta Central
   Hospital; University of Helsinki; Helsinki University Central Hospital;
   Hyvinkaan Sairaala
RP Nuutila, K (通讯作者)，Univ Helsinki, Inst Biomed, POB 63, FIN-00014 Helsinki, Finland.
EM kristo.nuutila@helsinki.fi
RI Kankuri, Esko/AGF-5256-2022
OI Kankuri, Esko/0000-0002-2193-8773; harjula, ari/0000-0001-6691-3636
FU Finnish Funding Agency for Technology and Innovation (TEKES),
   Regenerative Active Matrix (RAM) [40102/08]
FX Lahja Eurajoki (Helsinki), Leena Liljeroos (Pori), and Ulla
   Hohtari-Kivimaki (Pori) are gratefully acknowledged for their skilful
   technical assistance. We thank Hannu Kuokkanen and Ilkka Kaartinen for
   kind assistance with the ethics permits. The project was funded by the
   Finnish Funding Agency for Technology and Innovation (TEKES),
   Regenerative Active Matrix (RAM) project (40102/08).
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NR 30
TC 36
Z9 41
U1 0
U2 16
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0305-4179
EI 1879-1409
J9 BURNS
JI Burns
PD JUN
PY 2013
VL 39
IS 4
BP 687
EP 693
DI 10.1016/j.burns.2012.09.014
PG 7
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA 161RC
UT WOS:000320210000022
PM 23141686
DA 2026-07-24
ER

PT J
AU Farré, R
   Rodríguez-Lázaro, MA
   Gonzalez-Martin, J
   Castro, P
   Hospital, T
   Compta, Y
   Solana, G
   Gozal, D
   Otero, J
AF Farre, Ramon
   Rodriguez-Lazaro, Miguel A.
   Gonzalez-Martin, Julian
   Castro, Pedro
   Hospital, Teresa
   Compta, Yaroslau
   Solana, Gorka
   Gozal, David
   Otero, Jorge
TI Device for Negative Pressure Wound Therapy in Low-Resource Regions:
   Open-Source Description and Bench Test Evaluation
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE vacuum pressure therapy; wound healing; low-cost medical device; low-and
   middle-income countries; open-source hardware
ID VACUUM-ASSISTED CLOSURE
AB Background: Negative (vacuum) pressure therapy promotes wound healing. However, commercially available devices are unaffordable to most potential users in low- and middle-income countries (LMICs), limiting access to many patients who could benefit from this treatment. This study aimed to design and test a cheap and easy-to-build negative pressure device and provide its detailed open-source description, thereby enabling free replication. Methods: the negative pressure device was built using off-the-shelf materials available via e-commerce and was based on a small pump, a pressure transducer, and the simplest Arduino controller with a digital display (total retail cost <= 75 US$). The device allows the user to set any therapeutic range of intermittent negative pressure and has two independent safety mechanisms. The performance of the low-cost device was carefully tested on the bench using a phantom wound, producing a realistic exudate flow rate. Results: the device generates the pressure patterns set by the user (25-175 mmHg of vacuum pressure, 0-60 min periods) and can drain exudate flows within the clinical range (up to 1 L/h). Conclusions: a novel, low-cost, easy-to-build negative pressure device for wound healing displays excellent technical performance. The open-source hardware description provided here, which allows for free replication and use in LMICs, will facilitate the application and wider utilization of this therapy to patients.
C1 [Farre, Ramon; Rodriguez-Lazaro, Miguel A.; Otero, Jorge] Univ Barcelona, Fac Med & Ciencies Salut, Unitat Biofis & Bioengn, Barcelona 08036, Spain.
   [Farre, Ramon; Otero, Jorge] CIBER Enfermedades Resp, Madrid 28029, Spain.
   [Farre, Ramon; Castro, Pedro; Compta, Yaroslau] Inst Investigac Biomed August Pi Sunyer, Barcelona 08036, Spain.
   [Gonzalez-Martin, Julian] Univ Barcelona, ISGlobal, Hosp Clin, Microbiol Dept,CDB, Barcelona 08036, Spain.
   [Gonzalez-Martin, Julian] Inst Salud Carlos III, CIBER Infect Dis CIBERINFEC, Madrid 28029, Spain.
   [Castro, Pedro; Hospital, Teresa] Hosp Clin Barcelona, Internal Med Dept, Intens Care Unit, Barcelona 08036, Spain.
   [Compta, Yaroslau] Hosp Clin Barcelona, Inst Neurociencies, Serv Neurol, Parkinsons Dis & Movement Disorders Unit, Barcelona 08036, Spain.
   [Compta, Yaroslau] Univ Barcelona, Maeztu Ctr, Inst Neurociencies, Barcelona 08036, Spain.
   [Solana, Gorka] Univ Save, Fac Engenharias & Tecnol, Maxixe, Mozambique.
   [Gozal, David] Univ Missouri, Sch Med, Dept Child Hlth, Columbia, MO 65212 USA.
C3 University of Barcelona; CIBER - Centro de Investigacion Biomedica en
   Red; CIBERES; University of Barcelona; Hospital Clinic de Barcelona;
   IDIBAPS; ISGlobal; University of Barcelona; Hospital Clinic de
   Barcelona; Instituto de Salud Carlos III; University of Barcelona;
   Hospital Clinic de Barcelona; University of Barcelona; Hospital Clinic
   de Barcelona; University of Barcelona; University of Missouri System;
   University of Missouri Columbia
RP Farré, R (通讯作者)，Univ Barcelona, Fac Med & Ciencies Salut, Unitat Biofis & Bioengn, Barcelona 08036, Spain.; Farré, R (通讯作者)，CIBER Enfermedades Resp, Madrid 28029, Spain.; Farré, R (通讯作者)，Inst Investigac Biomed August Pi Sunyer, Barcelona 08036, Spain.
EM rfarre@ub.edu
RI Gozal, David/ABH-3805-2020; Farre, Ramon/L-2664-2017; Castro Rebollo,
   Pedro/AAF-4792-2021; Compta, Yaroslau/U-8298-2017; Solana Arteche,
   Gorka/AAH-7925-2020; Gonzalez-Martin, Julian/AGS-6795-2022; Compta,
   Yaroslau/U-8298-2017
OI Gozal, David/0000-0001-8195-6036; Farre, Ramon/0000-0002-9084-7824;
   Castro Rebollo, Pedro/0000-0002-6118-8970; Compta,
   Yaroslau/0000-0001-6443-0104; Solana Arteche, Gorka/0000-0002-1212-0574;
   
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
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NR 38
TC 2
Z9 2
U1 0
U2 2
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD SEP
PY 2022
VL 11
IS 18
AR 5417
DI 10.3390/jcm11185417
PG 9
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 4S6GB
UT WOS:000857536000001
PM 36143070
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Graham, C
   Vuagniaux, A
   Adamo, M
   Knarr, J
AF Graham, Charlotte
   Vuagniaux, Andre
   Adamo, Morgan
   Knarr, Jacob
TI LIMB SALVAGE WITHOUT SURGICAL DEBRIDEMENT: WOC NURSE LED USE OF
   NEGATIVE-PRESSURE WOUND THERAPY WITH INSTILLATION AND DWELL (NPWTi-d) OF
   HYPOCHLOROUS ACID FOR LIMB SALVAGE AND SPLIT THICKNESS SKIN GRAFTING
   (STSG) PREPARATION WITHOUT SURGICAL DEBRIDEMENT
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Meeting Abstract
C1 [Graham, Charlotte; Vuagniaux, Andre; Adamo, Morgan] Wound Care, Aurora, CO USA.
   [Knarr, Jacob] Inpatient Wound Ost Care, Aurora, CO USA.
EM charlotte.graham@uchealth.org; andre.vuagniaux@uchealth.org;
   morgan.adamo@uchealth.org; jacob.knarr@uchealth.org
CR Bollero D, 2016, INT WOUND J, V13, P768, DOI 10.1111/iwj.12373
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   GABRIEL A, 2020, GLOBAL OPEN, V8, DOI DOI 10.1097/GOX.0000000000002801
NR 3
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2023
VL 50
IS 3
SU S
MA PI30
BP S32
EP S32
PG 1
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA S6IO9
UT WOS:001072181900071
DA 2026-07-24
ER

PT J
AU Kirsner, RS
   Hurd, T
AF Kirsner, Robert S.
   Hurd, Theresa
TI Assessing the Need for Negative Pressure Wound Therapy Utilization
   Guidelines: An Overview of the Challenges With Providing Optimal Care
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Review
DE negative pressure wound therapy; single-use negative pressure wound
   therapy; wound management; quality of life; operational efficiencies;
   financial efficiencies
ID COST-MINIMIZATION ANALYSIS; EXPERIENCES; IMPACT; DEVICE; NPWT
AB Negative pressure wound therapy (NPWT) has evolved beyond its original design as a stationary, reusable system (traditional NPWT [tNPWT]) and is now also available as a single-use, portable device (sNPWT). No established guidance exists for selecting the appropriate system to treat specific wound types in various settings. This article reviews the current practice and challenges associated with NPWT. Relevant literature was reviewed to provide a background on current practice. An online quantitative survey was performed during October and November 2018 among users of NPWT based in acute care settings across 6 countries (Australia, France, Germany, Italy, the United Kingdom, and the United States) to elucidate the operational and financial components considered in determining and/or thwarting efficacious use of NPWT. Data from recruited participants were collected, analyzed, and tabulated by an independent research company. All findings were reported as numbers/percentages. Wound size and depth, as well as the amount and/or type of exudate, were found to be among key factors in selecting NPWT; patient quality of life in terms of mobility, independence, and attitude toward treatment may be factors in adherence with prescribed care. Clinicians were not consistently knowledgeable about the financial and operational challenges of utilization presented by large fleets of NPWT pumps, nor were other institutional employees such as payers and discharge planners. Evidence-based recommendations are needed to guide decisions regarding NPWT systems, which in turn may improve therapy implementation, access to care, and patient quality of life, while driving operational and financial efficiencies for health care providers.
C1 [Kirsner, Robert S.] Univ Miami, Miller Sch Med, Hosp & Clin Wound Ctr, Dr Phillip Frost Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA.
   [Hurd, Theresa] Nursing Practice Solut, Stevensville, ON, Canada.
   [Hurd, Theresa] Catholic Hlth, Buffalo, NY USA.
C3 University of Miami
RP Kirsner, RS (通讯作者)，Univ Miami, Dept Dermatol & Cutaneous Surg, Sch Med, 1600 NW 10th Ave,RMSB 2023A, Miami, FL 33136 USA.
EM RKirsner@med.miami.edu
CR Adeyemi A, 2018, WOUNDS, V30, pE13
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   World Union of Wound Healing Societies consensus document, 2019, WOUNDS INT
NR 42
TC 11
Z9 11
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD DEC
PY 2020
VL 32
IS 12
BP 328
EP 333
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA QI0SU
UT WOS:000618686200001
PM 33472158
DA 2026-07-24
ER

PT J
AU Wihbey, KA
   Joyce, EM
   Spalding, ZT
   Jones, HJ
   MacKenzie, TA
   Evans, RH
   Fung, JL
   Goldman, MB
   Erekson, E
AF Wihbey, Kristina A.
   Joyce, Ellen M.
   Spalding, Zachary T.
   Jones, Hayley J.
   MacKenzie, Todd A.
   Evans, Rebecca H.
   Fung, June L.
   Goldman, Marlene B.
   Erekson, Elisabeth
TI Prophylactic Negative Pressure Wound Therapy and Wound Complication
   After Cesarean Delivery in Women With Class II or III Obesity A
   Randomized Controlled Trial
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Article
ID RISK
AB OBJECTIVE: To compare the occurrence of superficial surgical site infections in obese women using prophylactic negative pressure therapy with standard dressings after cesarean delivery.
   Methods: We conducted a randomized controlled, nonblinded, two-center study of prophylactic negative pressure therapy compared with standard surgical dressings placed at the time of primary closure at cesarean delivery in obese women with body mass indexes (BMI) of 35 or higher (ie, class II and III obesity). Our primary outcome was occurrence of a superficial surgical site infection. We assumed a superficial surgical site infection occurrence rate of 20% and intended to recruit 400 women. However, after low enrollment of 166 women over 24 months, an interim analysis for futility was conducted and the decision was made to halt the study.
   RESULTS: Women were recruited between January 5, 2015, and January 7, 2017, from two sites. The mean BMI on admission was 44.9 (68) for the prophylactic negative wound therapy group and 43.4 (67) for the standard dressing group. There were no differences in the occurrence of observed superficial surgical site infections between women using prophylactic negative pressure wound therapy (12/80 [15%]) compared with women who received the standard dressing (8/81 [10%], P=.35, relative risk 1.52, 95% CI 0.66-3.52). There were no differences in the occurrence of composite wound complications between women using prophylactic negative pressure wound therapy (25/80 [31%]) compared with women who received the standard dressing (24/81 [30%], P=.87).
   CONCLUSION: In this randomized controlled trial that did not achieve full anticipated enrollment, we did not observe a decrease in superficial surgical site infections after cesarean delivery in obese women with the use of prophylactic negative pressure wound therapy.
C1 Geisel Sch Med Dartmouth, Dept Obstet & Gynecol, Lebanon, NH USA.
   Geisel Sch Med Dartmouth, Dept Biomed Data Sci, Lebanon, NH USA.
   Geisel Sch Med Dartmouth, Dartmouth Inst Hlth Policy & Clin Practice, Lebanon, NH USA.
C3 Dartmouth College; Dartmouth College; Dartmouth College
RP Wihbey, KA (通讯作者)，Geisel Sch Med Dartmouth, Dept Obstet & Gynecol, 189 N Main St, Concord, NH 03301 USA.
EM kwihbey@crhc.org
OI Evans, Rebecca/0000-0002-0108-255X
FU KCI Medical (San Antonio, Texas)
FX The devices used in this study were provided by an unrestricted research
   grant from KCI Medical (San Antonio, Texas). KCI Medical had no role in
   the study design, data collection, or data analysis. Final results of
   the study were shared with the company before manuscript submission;
   however, the investigators were not bound to incorporate KCI's comments.
   The authors' decision as to what the manuscript contained was final.
CR Alanis MC, 2010, AM J OBSTET GYNECOL, V203, DOI 10.1016/j.ajog.2010.06.049
   [Anonymous], 2011, Obstet Gynecol, V117, P1472, DOI 10.1097/AOG.0b013e3182238c31
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   National Healthcare Safety Network Centers for Disease Control and Prevention, Surgical site infection (SSI) event
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NR 10
TC 31
Z9 33
U1 1
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0029-7844
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD AUG
PY 2018
VL 132
IS 2
BP 377
EP 384
DI 10.1097/AOG.0000000000002744
PG 8
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA GR3GB
UT WOS:000442476900021
PM 29995726
DA 2026-07-24
ER

PT J
AU Tuuli, MG
   Liu, JX
   Tita, ATN
   Longo, S
   Trudell, A
   Carter, EB
   Shanks, A
   Woolfolk, C
   Caughey, AB
   Warren, DK
   Odibo, AO
   Colditz, G
   Macones, GA
   Harper, L
AF Tuuli, Methodius G.
   Liu, Jingxia
   Tita, Alan T. N.
   Longo, Sherri
   Trudell, Amanda
   Carter, Ebony B.
   Shanks, Anthony
   Woolfolk, Candice
   Caughey, Aaron B.
   Warren, David K.
   Odibo, Anthony O.
   Colditz, Graham
   Macones, George A.
   Harper, Lorie
TI Effect of Prophylactic Negative Pressure Wound Therapy vs Standard Wound
   Dressing on Surgical-Site Infection in Obese Women After Cesarean
   Delivery: A Randomized Clinical Trial
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Article
ID POSTDISCHARGE SURVEILLANCE; MATERNAL OBESITY; RISK; MORBIDITY; SECTION
AB IMPORTANCE: Obesity increases the risk of both cesarean delivery and surgical-site infection. Despite widespread use, it is unclear whether prophylactic negative pressure wound therapy reduces surgical-site infection after cesarean delivery in obese women.
   OBJECTIVE: To evaluate whether prophylactic negative pressure wound therapy, initiated immediately after cesarean delivery, lowers the risk of surgical-site infections compared with standard wound dressing in obese women.
   DESIGN, SETTING, AND PARTICIPANTS: Multicenter randomized trial conducted from February 8, 2017, through November 13, 2019, at 4 academic and 2 community hospitals across the United States. Obese women undergoing planned or unplanned cesarean delivery were eligible. The study was terminated after 1624 of 2850 participants were recruited when a planned interim analysis showed increased adverse events in the negative pressure group and futility for the primary outcome. Final follow-up was December 18, 2019.
   INTERVENTIONS: Participants were randomly assigned to either undergo prophylactic negative pressure wound therapy, with application of the negative pressure device immediately after repair of the surgical incision (n = 816), or receive standard wound dressing (n = 808).
   MAIN OUTCOMES AND MEASURES: The primary outcome was superficial or deep surgical-site infection according to the Centers for Disease Control and Prevention definitions. Secondary outcomes included other wound complications, composite of surgical-site infections and other wound complications, and adverse skin reactions.
   RESULTS: Of the 1624 women randomized (mean age, 30.4 years, mean body mass index, 39.5), 1608 (99%) completed the study: 806 in the negative pressure group (median duration of negative pressure, 4 days) and 802 in the standard dressing group. Superficial or deep surgical-site infection was diagnosed in 29 participants (3.6%) in the negative pressure group and 27 (3.4%) in the standard dressing group (difference, 0.36%; 95% CI, -1.46% to 2.19%, P = .70). Of 30 prespecified secondary end points, 25 showed no significant differences, including other wound complications (2.6% vs 3.1%; difference, -0.53%; 95% CI, -1.93% to 0.88%; P = .46) and composite of surgical-site infections and other wound complications (6.5% vs 6.7%; difference, -0.27%; 95% CI, -2.71% to 2.25%; P = .83). Adverse skin reactions were significantly more frequent in the negative pressure group (7.0% vs 0.6%; difference, 6.95%; 95% CI, 1.86% to 12.03%; P < .001).
   CONCLUSIONS and relevance: Among obese women undergoing cesarean delivery, prophylactic negative pressure wound therapy, compared with standard wound dressing, did not significantly reduce the risk of surgical-site infection. These findings do not support routine use of prophylactic negative pressure wound therapy in obese women after cesarean delivery.
C1 [Tuuli, Methodius G.; Shanks, Anthony] Indiana Univ Sch Med, Dept Obstet & Gynecol, 550 N Univ Blvd,2440, Indianapolis, IN 46202 USA.
   [Liu, Jingxia; Colditz, Graham] Washington Univ, Sch Med, Dept Surg, St Louis, MO 63110 USA.
   [Tita, Alan T. N.; Harper, Lorie] Univ Alabama Birmingham, Dept Obstet & Gynecol, Birmingham, AL USA.
   [Tita, Alan T. N.; Harper, Lorie] Univ Alabama Birmingham, Ctr Womens Reprod Hlth, Birmingham, AL USA.
   [Longo, Sherri] Ochsner Hlth, Dept Obstet & Gynecol, New Orleans, LA USA.
   [Trudell, Amanda] BJC Med Grp, Div Maternal Fetal Med, St Louis, MO USA.
   [Carter, Ebony B.; Woolfolk, Candice] Washington Univ, Sch Med, Dept Obstet & Gynecol, St Louis, MO 63110 USA.
   [Caughey, Aaron B.] Oregon Hlth & Sci Univ, Dept Obstet & Gynecol, Portland, OR 97201 USA.
   [Warren, David K.] Washington Univ, Sch Med, Dept Med, St Louis, MO 63110 USA.
   [Odibo, Anthony O.] Univ S Florida, Dept Obstet & Gynecol, Sch Med, Tampa, FL 33620 USA.
   [Macones, George A.] Univ Texas Austin, Dell Sch Med, Dept Obstet & Gynecol, Austin, TX 78712 USA.
C3 Indiana University System; Indiana University Bloomington; Washington
   University (WUSTL); University of Alabama System; University of Alabama
   Birmingham; University of Alabama System; University of Alabama
   Birmingham; Washington University (WUSTL); Oregon Health & Science
   University; Washington University (WUSTL); State University System of
   Florida; University of South Florida; University of Texas System;
   University of Texas Austin
RP Tuuli, MG (通讯作者)，Indiana Univ Sch Med, Dept Obstet & Gynecol, 550 N Univ Blvd,2440, Indianapolis, IN 46202 USA.
EM methodiustuuli@yahoo.com
RI Longo, Sherri/G-3969-2011; Colditz, Graham/A-3963-2009
OI Colditz, Graham/0000-0002-7307-0291; Liu, Jingxia/0000-0002-9434-7907;
   Shanks, Anthony/0000-0001-5916-1683; Warren, David/0000-0001-8679-8241
FU Eunice Kennedy Shriver NICHD [R01HD086007]
FX The study was funded by grant R01HD086007 from the Eunice Kennedy
   Shriver NICHD (Drs Tuuli and Harper). In addition, Acelity donated
   negative pressure devices and provided supplemental funding.
CR Anaya Daniel A, 2006, Surg Infect (Larchmt), V7, P473, DOI 10.1089/sur.2006.7.473
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NR 37
TC 69
Z9 80
U1 0
U2 14
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD SEP 22
PY 2020
VL 324
IS 12
BP 1180
EP 1189
DI 10.1001/jama.2020.13361
PG 10
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA OS4RZ
UT WOS:000590153400031
PM 32960242
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Wei, ZY
   Zhu, JF
   Lin, TL
   Cai, HH
   Fang, XJ
   Zhu, YX
   Yang, XL
   Cheng, JT
AF Wei, Zhiyi
   Zhu, Jingfa
   Lin, Tianlai
   Cai, Hehui
   Fang, Xiangjian
   Zhu, Yixin
   Yang, Xiaolan
   Cheng, Juntao
TI Application of damage control surgery in patients with sacrococcygeal
   deep decubitus ulcers complicated by sepsis
SO JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
LA English
DT Article
DE Sacrococcygeal deep decubitus ulcer; sepsis; damage control surgery;
   modified rhomboid flap; vacuum sealing drainage; bedsore
ID DESIGN; FLAP
AB Objective To evaluate the clinical application of damage control surgery (DCS) in patients with sacrococcygeal deep decubitus ulcers complicated by sepsis. Methods We conducted a 3-year retrospective clinical study of 32 patients with deep sacrococcygeal bedsores and sepsis admitted from January 2018 to January 2021. According to the concept of DCS, the wound was temporarily closed with vacuum sealing drainage after primary debridement, and a local rhomboid flap was designed to repair the wound in the second stage. Finally, the clinical therapeutic effect was observed. Results Twenty-nine patients were treated with skin flap translocation and were cured clinically. Specifically, the skin flap survived in 27 of the 29 patients after the first translocation attempt (success rate of 93.1%). One patient developed incisional dehiscence, and one patient developed a hydrocele under the skin flap. Conclusions Application of DCS in patients with sacrococcygeal deep decubitus ulcers complicated by sepsis improves the therapeutic success rate and reduces the risks of the operation and complication rate. It has unique advantages and is worthy of clinical promotion.
C1 [Wei, Zhiyi; Fang, Xiangjian; Zhu, Yixin; Yang, Xiaolan; Cheng, Juntao] Quanzhou First Hosp, Dept Burn Intens Care Unit, 250 Dongjie Rd, Quanzhou 362000, Fujian, Peoples R China.
   [Zhu, Jingfa] Quanzhou First Hosp, Dept Emergency, Quanzhou, Fujian, Peoples R China.
   [Lin, Tianlai] Quanzhou First Hosp, Dept Intens Care Unit, Quanzhou, Fujian, Peoples R China.
   [Cai, Hehui] Quanzhou First Hosp, Dept Med Lab, Quanzhou, Fujian, Peoples R China.
RP Cheng, JT (通讯作者)，Quanzhou First Hosp, Dept Burn Intens Care Unit, 250 Dongjie Rd, Quanzhou 362000, Fujian, Peoples R China.
EM c5481@sina.com
OI Yang, Xiaolan/0000-0003-4177-5921; Cheng, Juntao/0000-0002-4236-3817
CR Chou CY, 2018, OSTOMY WOUND MANAG, V64, P40, DOI 10.25270/owm.2018.3.4044
   Cui N, 2019, J INT MED RES, V47, P1573, DOI 10.1177/0300060518822404
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NR 20
TC 3
Z9 3
U1 0
U2 6
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 0300-0605
EI 1473-2300
J9 J INT MED RES
JI J. Int. Med. Res.
PD OCT
PY 2021
VL 49
IS 10
AR 03000605211049876
DI 10.1177/03000605211049876
PG 10
WC Medicine, Research & Experimental; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Pharmacology & Pharmacy
GA WP7TV
UT WOS:000713330000001
PM 34719986
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Wu, CJ
   Tsai, YC
   Li, YC
   Su, MS
   Chou, YY
   Tsao, MC
   Tzeng, YS
AF Wu, Chien-Ju
   Tsai, Yu-Chi
   Li, Yi-Chen
   Su, Ming-Shan
   Chou, Yu-Yu
   Tsao, Ming-Cheng
   Tzeng, Yuan-Sheng
TI Is Primary Closure Safe and Effective for Sacral Pressure Ulcers?
   Single-Surgeon Experience With Negative Pressure Wound Therapy in a
   Medical Center and a Regional Hospital
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE closed-incision negative pressure wound therapy (CI-NPWT); negative
   pressure wound therapy (NPWT); primary closure; sacral pressure ulcer;
   tension-reducing wound closure; wound reconstruction
AB BackgroundSacral pressure ulcers present a major reconstructive challenge, especially in elderly and bedridden patients. Although negative pressure wound therapy (NPWT) has been widely used in wound management, its integration into surgical protocols for pressure ulcer closure is underreported in midlevel medical centers. We aimed to evaluate the safety, efficacy, and reproducibility of a streamlined surgical strategy for sacral pressure ulcers combining debridement, primary closure, and closed-incision-NPWT (CI-NPWT) and examine the outcomes in patients treated in 2 institutional settings with different resource levels.MethodsThis retrospective observational cohort study included 35 patients (median age, 76 years; 66% female) with stage III-IV sacral pressure ulcers who underwent surgical reconstruction using a standardized approach involving debridement, tension-reducing wound closure, and CI-NPWT. All procedures were performed by a single reconstructive surgeon at both a medical center and a regional hospital.ResultsAmong the 35 patients, 33 were treated at the tertiary center and 2 at the regional hospital. The median wound size was 9 x 6 cm (range 3 x 5-13 x 12 cm). Most patients were elderly with multiple comorbidities. CI-NPWT effectively supported primary wound closure with no major complications. Minor wound-edge dehiscence occurred in a few patients and was managed conservatively. All wounds healed completely.ConclusionA simple and consistent surgical protocol combining primary closure with CI-NPWT is safe, effective, and reproducible in both medical center and regional hospital settings.
C1 [Tsai, Yu-Chi; Li, Yi-Chen; Tzeng, Yuan-Sheng] Natl Def Med Univ, Div Plast & Reconstruct Surg, Sumsun, Turkiye.
   [Li, Yi-Chen] Natl Def Med Univ, Triserv Gen Hosp, Dept Surg, Div Traumatol, Taipei, Taiwan.
   [Su, Ming-Shan; Tsao, Ming-Cheng; Tzeng, Yuan-Sheng] Zuoying Armed Forces Gen Hosp, Dept Surg, Div Plast Surg, Hamilton, ON, Canada.
   [Chou, Yu-Yu; Tzeng, Yuan-Sheng] Zuoying Armed Forces Gen Hosp, Dept Gen Surg, Kaohsiung, Taiwan.
C3 Samsun Training & Research Hospital; Tri-Service General Hospital;
   National Defense Medical University; McMaster University
RP Tzeng, YS (通讯作者)，Dept Surg, Div Plast & Reconstruct Surg, 325,Sect 2,Cheng Gung Rd, Taipei 11490, Taiwan.
EM wuchienjud33d3@edusbm.com; yuchitsaif47jh6@edusbm.com;
   yichenlig5h78@edusbm.com; mingshansu3d56@edusbm.com;
   yuyuchoufg5h8@edusbm.com; mingchengtsao3d67@edusbm.com;
   yuanshengtzengg676@edusbm.com
RI Tzeng, Yuan-sheng/AAD-8843-2020
FU Tri-Service General Hospital [TSGH_E_114288]
FX Funding source: This work was supported by the Tri-Service General
   Hospital (TSGH_E_114288).
CR Argenta LC., 1997, Plast Reconstr Surg, V100, P553
   Chang CK, 2017, INT WOUND J, V14, P1170, DOI 10.1111/iwj.12781
   Chen CY, 2020, MEDICINE, V99, DOI 10.1097/MD.0000000000023022
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NR 10
TC 0
Z9 0
U1 1
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD FEB
PY 2026
VL 96
IS 2
BP 174
EP 178
DI 10.1097/SAP.0000000000004625
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CM3WX
UT WOS:001669226100004
PM 41490225
DA 2026-07-24
ER

PT J
AU Juengsirakulwit, K
   Amornfa, J
AF Juengsirakulwit, Kusawadee
   Amornfa, Jiraphorn
TI Effectiveness of closed incisional negative pressure wound therapy in
   pediatric spinal dysraphism: a single-center retrospective case series
SO CHILDS NERVOUS SYSTEM
LA English
DT Article
DE Spinal dysraphism; Closed incisional negative pressure wound therapy;
   ciNPWT; Myelomeningocele; Pediatric neurosurgery; Postoperative wound
   complication; Surgical site infection; CSF leakage
ID CORD LIPOMAS
AB Introduction Postoperative wound complications - including surgical site infection (SSI), cerebrospinal fluid (CSF) leakage, and wound dehiscence - remain a significant challenge following surgery for spinal dysraphism, particularly in neonates and infants. Closed incisional negative pressure wound therapy (ciNPWT) has demonstrated benefit in several surgical sub-specialties; however, evidence regarding its routine use in pediatric spinal dysraphism surgery is limited. MethodsA retrospective review was conducted of all pediatric patients (age < 18 years) who underwent surgery for spinal dysraphism and received ciNPWT as part of postoperative wound management at King Chulalongkorn Memorial Hospital between June 2020 and March 2024. Primary outcomes included postoperative wound complications (SSI, CSF leakage, wound dehiscence, and wound necrosis) within 30 days of surgery. The number of postoperative dressing changes was recorded as a secondary outcome and surrogate marker of wound care burden. Results A total of 28 patients were included: 8 with open spinal dysraphism (myelomeningocele, myeloschisis, or hem-imyelomeningocele) and 20 with closed spinal dysraphism or related conditions (including 2 pygopagus conjoined twins). The median number of dressing changes was 3 (range 3-5) for open dysraphism and 2 (range 1-2) for closed dysraphism. Primary wound closure was achieved in all cases. No postoperative wound complications - including SSI, CSF leakage, wound dehiscence, or wound necrosis - were observed during the follow-up period. Conclusion Closed incisional negative pressure wound therapy appears to be a safe and effective adjunct for postoperative wound management in pediatric spinal dysraphism surgery, demonstrating favorable wound outcomes across both open and closed dysraphism types, including complex high-risk cases.
C1 [Juengsirakulwit, Kusawadee; Amornfa, Jiraphorn] King Chulalongkorn Mem Hosp, Dept Surg, Neurosurg Unit, Thai Red Cross Soc, Bangkok, Thailand.
C3 Thai Red Cross Society; Chulalongkorn University
RP Juengsirakulwit, K (通讯作者)，King Chulalongkorn Mem Hosp, Dept Surg, Neurosurg Unit, Thai Red Cross Soc, Bangkok, Thailand.
EM Kusawadee.J@chulahospital.org
CR Bastawisy Karim A, 2025, Cureus, V17, pe82237, DOI [10.7759/cureus.82237, 10.7759/cureus.82237]
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NR 10
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0256-7040
EI 1433-0350
J9 CHILD NERV SYST
JI Childs Nerv. Syst.
PD MAY 16
PY 2026
VL 42
IS 1
AR 222
DI 10.1007/s00381-026-07318-5
EA MAY 2026
PG 7
WC Clinical Neurology; Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Pediatrics; Surgery
GA IB1EF
UT WOS:001767477800001
PM 42141294
DA 2026-07-24
ER

PT J
AU Zhang, JH
   Xie, ZJ
   Zhao, XB
   Su, W
AF Zhang, Jianhua
   Xie, Zhenjun
   Zhao, Xiaobing
   Su, Wei
TI Tube posterior tibial artery flow-through free flap for salvaging upper
   limbs with contaminated soft tissue defects and arterial injuries
SO JOURNAL OF HAND SURGERY-EUROPEAN VOLUME
LA English
DT Article
DE Flow-through flap; posterior tibial artery; severely contaminated;
   vacuum sealing drainage (VSD)
ID TEMPORARY ECTOPIC IMPLANTATION; UPPER EXTREMITY; RECONSTRUCTION;
   COMPLICATIONS; FRACTURES; THERAPY; TRAUMA
AB The tube posterior tibial artery flow-through free flap technique is proposed for salvaging upper limbs with severely contaminated or infected soft tissue defects and major arterial injuries. Between January 2016 and February 2024, six patients were treated using this method. This is a two-stage approach involving initial restoration of blood supply via a tube posterior tibial artery flow-through free flap, followed by delayed soft tissue coverage utilizing the unfolded tube flap after a series of wound debridements and vacuum sealing drainage treatments. All upper limbs and flaps completely survived. At the 2-year follow-up, the grip and pinch strength of the injured hands reached 37% (range 29-72%)and 31% (range 12-42%) of the contralateral sides, respectively. The mean Disabilities of the Arm, Shoulder, and Hand score was 60 (range 53-67). This study demonstrates the feasibility and efficacy of the tube posterior tibial artery flow-through free flap technique in complex upper limb salvage cases.Level of evidence: IV
C1 [Zhang, Jianhua; Su, Wei] Guangxi Med Univ, Affiliated Hosp 1, Dept Orthopaed Trauma & Hand Surg, Nanning 530021, Guangxi Zhuang, Peoples R China.
   [Zhang, Jianhua; Xie, Zhenjun; Zhao, Xiaobing] Henan Prov Peoples Hosp, Dept Hand & Foot Microsurg, Zhengzhou, Peoples R China.
C3 Guangxi Medical University; Zhengzhou University
RP Su, W (通讯作者)，Guangxi Med Univ, Affiliated Hosp 1, Dept Orthopaed Trauma & Hand Surg, Nanning 530021, Guangxi Zhuang, Peoples R China.
EM gxsuwei@163.com
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NR 27
TC 0
Z9 0
U1 0
U2 0
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1753-1934
EI 2043-6289
J9 J HAND SURG-EUR VOL
JI J. Hand Surg.-Eur. Vol.
PD FEB
PY 2026
VL 51
IS 2
BP 209
EP 215
DI 10.1177/17531934251367567
EA AUG 2025
PG 7
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA DB1TI
UT WOS:001563529100001
PM 40884839
DA 2026-07-24
ER

PT J
AU Shimbo, K
   Saiki, T
   Kawamoto, H
   Koshima, I
AF Shimbo, Keisuke
   Saiki, Tatsuhiko
   Kawamoto, Haruka
   Koshima, Isao
TI Implant Salvage in Patients With Severe Post-Fracture Fixation Surgical
   Site Infection Using Negative Pressure Wound Therapy With Intramedullary
   and Subcutaneous Antibiotic Perfusion
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE surgical site infection; negative pressure wound therapy; negative
   pressure wound therapy with instillation and dwell time; intramedullary
   antibiotic perfusion; subcutaneous antibiotic perfusion; hardware
   salvage
ID ORTHOPEDIC IMPLANTS; INSTILLATION; PROPHYLAXIS; REMOVAL; BEADS
AB Introduction. Post-fracture fixation surgical site infection (SSI) is a devastating complication, and the standard-of-care therapeutic regimen is ineffective in managing it. Negative pressure wound therapy with instillation and dwell time (NPWTi-d) can be used to salvage orthopedic fixation hardware in the setting of infection; moreover, NPWTi- d can be used effectively in the management of superficial post-fracture fixation SSI. Case Report. Two cases were treated with NPWTi-d. Because of difficulties disrupting the deep dead space biofilm in a deep post-fracture fixation SSI (and because of the risk for bone infection), a doublelumen tube was used for subcutaneous antibiotic perfusion and dead space suction drainage, and bone marrow needles were used for intramedullary antibiotic perfusion to manage or prevent early osteomyelitis. The 2 patients with severe SSI after below-knee fracture fixation were treated with continuous intramedullary and subcutaneous antibiotic perfusion with NPWT to salvage the orthopedic implant. The debrided wounds of the lower leg and heel were reconstructed with free flaps and incisional NPWT, followed by administration of continuous intramedullary and subcutaneous antibiotic perfusion to preserve the titanium plates. In both patients, the wounds healed without complications and remained healed after more than 7 months. Conclusions. Continuous local antibiotic perfusion around infected orthopedic fixation hardware can be an ideal treatment for patients with SSI after fracture fixation. Although this technique can be improved further, it is more effective than conventional therapy in the management of severe post-fracture fixation SSI with a dead space.
C1 [Shimbo, Keisuke; Saiki, Tatsuhiko; Kawamoto, Haruka] Hiroshima Prefectural Hosp, Hiroshima Byoin, Hiroshima, Japan.
   [Koshima, Isao] Hiroshima Univ Hosp, Int Ctr Lymphedema, Hiroshima Daigaku Byoin, Hiroshima, Japan.
C3 Hiroshima University
RP Shimbo, K (通讯作者)，5-54 Ujinakanda, Hiroshima, Hiroshima 7348530, Japan.
EM k_s08_10hyogo@hotmail.com
RI Shimbo, Keisuke/AFN-9685-2022
OI Shimbo, Keisuke/0000-0003-0761-4147
CR Anagnostakos K, 2009, ACTA ORTHOP, V80, P193, DOI 10.3109/17453670902884700
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   Dettmers R, 2016, OSTOMY WOUND MANAG, V62, P30
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   Kim PJ, 2020, INT WOUND J, V17, P174, DOI 10.1111/iwj.13254
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   Lawing CR, 2015, J BONE JOINT SURG AM, V97A, P1844, DOI 10.2106/JBJS.O.00072
   Lehner B, 2011, INT ORTHOP, V35, P1415, DOI 10.1007/s00264-011-1274-y
   Li SP, 2019, EUR SPINE J, V28, P2972, DOI 10.1007/s00586-019-06143-6
   Liu J, 2021, PLAST RECONSTR SURG, V147, p54S, DOI 10.1097/PRS.0000000000007622
   Minkowitz RB, 2007, J BONE JOINT SURG AM, V89A, P1906, DOI 10.2106/JBJS.F.01536
   Ukai T, 2020, J ORTHOP TRAUMATOL, V21, DOI 10.1186/s10195-020-00549-5
   Westgeest J, 2016, J ORTHOP TRAUMA, V30, P149, DOI 10.1097/BOT.0000000000000488
   Wininger DA, 1996, ANTIMICROB AGENTS CH, V40, P2675, DOI 10.1128/AAC.40.12.2675
NR 16
TC 0
Z9 0
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUN
PY 2022
VL 34
IS 6
BP E47
EP E50
DI 10.25270/wnds/21098
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA F6QY9
UT WOS:000983583600002
DA 2026-07-24
ER

PT J
AU Zhao, YH
   Feng, YH
   Deng, HT
   Huang, WQ
   Xu, LH
   Meng, XP
   Xie, XG
AF Zhao, Yao-Hua
   Feng, Yu-Hong
   Deng, Hai-Tao
   Huang, Wei-Qi
   Xu, Li-Hong
   Meng, Xian-Ping
   Xie, Xu-Gang
TI Therapeutic strategies for retention of cranioplasty titanium mesh after
   mesh exposure
SO ACTA NEUROCHIRURGICA
LA English
DT Article
DE Skull; Plastic surgery; Negative pressure wound therapy; Titanium;
   Prosthesis retention
ID AFFECTING GRAFT INFECTION
AB Background Titanium mesh exposure after cranioplasty is a possible complication and is usually managed by mesh removal and flap transfer, but the advantages of the rigid prosthesis are then lost. This study aimed to present our experience with negative pressure wound therapy combined with soft tissue dilation for retaining the titanium mesh in patients with mesh exposure after cranioplasty. Methods This retrospective study included patients treated between 01/2016 and 05/2019 at the Jiangyin Hospital Affiliated to Southeast University School of Medicine. The wound was cleaned, and a cystic space was created for the tissue dilator, which was used with a self-designed negative pressure dressing. After the target dilation was achieved, the repair was conducted while retaining the titanium mesh. Results Eight patients were included (seven males and one female; 53.6 +/- 8.8 (range, 43-65) years of age). The exposed mesh area ranged from 1 x 1 to 4 x 5.5 cm. The thinning scalp area around the exposed mesh ranged from 3.6 x 3.8 to 4 x 5.5 cm. Five patients had positive wound cultures and received sensitive antibiotics. The dilator embedding time was 20-28 days. The time of negative pressure wound therapy was 25-33 days. The hospital stay was 30-41 days. Primary wound healing was achieved in all eight patients. There were no signs of recurrence after 6-18 months of follow-up. The cranial CT scans were unremarkable. Conclusions Negative pressure wound therapy combined with soft tissue dilation for exposed titanium mesh after cranioplasty might help retain the titanium mesh.
C1 [Zhao, Yao-Hua; Deng, Hai-Tao; Huang, Wei-Qi; Xu, Li-Hong] Southeast Univ, Jiangyin Hosp, Sch Med, Dept Burn & Plast Surg, Jiangyin, Jiangsu, Peoples R China.
   [Feng, Yu-Hong] Southeast Univ, Jiangyin Hosp, Sch Med, Dept Nursing, Jiangyin, Jiangsu, Peoples R China.
   [Meng, Xian-Ping; Xie, Xu-Gang] Southeast Univ, Jiangyin Hosp, Sch Med, Dept Radiol, Jiangyin, Jiangsu, Peoples R China.
C3 Southeast University - China; Southeast University - China; Southeast
   University - China
RP Zhao, YH (通讯作者)，Southeast Univ, Jiangyin Hosp, Sch Med, Dept Burn & Plast Surg, Jiangyin, Jiangsu, Peoples R China.
EM zfh3r@sohu.com
FU Science and Technology Innovation Special Fund of Jiangyin, Jiangsu
   province [JY0603-020118-0014 PB]
FX This study was funded by the Science and Technology Innovation Special
   Fund of Jiangyin, Jiangsu province (grant number JY0603-020118-0014 PB).
CR Bhat AR, 2011, INDIAN J NEUROTRAUM, V8, P105, DOI 10.1016/S0973-0508(11)80009-2
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NR 21
TC 4
Z9 7
U1 0
U2 9
PU SPRINGER WIEN
PI Vienna
PA Prinz-Eugen-Strasse 8-10, A-1040 Vienna, AUSTRIA
SN 0001-6268
EI 0942-0940
J9 ACTA NEUROCHIR
JI Acta Neurochir.
PD DEC
PY 2022
VL 164
IS 12
BP 3101
EP 3106
DI 10.1007/s00701-022-05365-w
EA OCT 2022
PG 6
WC Clinical Neurology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA 6O0JN
UT WOS:000865673300001
PM 36214913
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Révész, ES
   Montskó, V
   Altorjay, A
   Reich, V
   Jakab, G
   Hangody, L
AF Revesz, Erzsebet Szabone
   Montsko, Valeria
   Altorjay, Aron
   Reich, Viktor
   Jakab, Gabriella
   Hangody, Laszlo
TI Comparison of different sampling procedures in negative pressure wound
   therapy used in wound infections following reconstruction of abdominal
   wall hernias with mesh on homogeneous patient material
SO ORVOSI HETILAP
LA Hungarian
DT Article
DE wound infection; abdominal wall hernias with mesh; negative pressure
   therapy; wound infection; abdominal wall hernias with mesh; negative
   pressure therapy
AB Introduction: The repair of postoperative abdominal hernias remains a challenge to this day, even though the surgery is sterile. Wound infection is a problem, which is exacerbated by the comorbidity of the patient population. The incorporation of foreign material always carries a risk of infection. In the event of wound infection, the possibility of hernia recurrence is 0.2-8%, while if the mesh also needs to be removed, the probability of recurrence is over 30%. Compared to open wound treatment, negative pressure therapy is more effective in promoting wound healing and preserving the implanted mesh. Materials and methods: In our study, we analyze the cases of a total of 30 patients who underwent onlay mesh abdominal hernia surgery between 2015 and 2023, during which wound dehiscence occurred. In all cases, wound exudate culture and negative pressure wound therapy were performed. In 15 patients, swab samples were taken, while in the other 15, swab, sponge, and tissue roller samples were taken. Swab samples mainly revealed skin flora, which was Gram-positive in 71% of cases. The results of the tissue roller and sponge swab cultures showed Gram-negative pathogens in 50% of cases. Results: The sponge swab and tissue roller cultures provided additional information on the bacterial load. Negative pressure wound therapy meant that the mesh did not need to be removed. Conclusion: During negative pressure wound therapy, cultures taken using multiple methods also helped in the selection of antibiotics. Vacuum therapy used for mesh removal reduces bacterial load and accelerates granulation. Hernia recurrence and mesh removal are significantly reduced.
C1 [Revesz, Erzsebet Szabone; Altorjay, Aron; Reich, Viktor] Fejer Varmegyei Szent Gyorgy Egyet Oktato Korhaz, Sebeszeti Osztaly, Szekesfehervar, Hungary.
   [Montsko, Valeria] Fejer Varmegyei Szent Gyorgy Egyet Oktato Korhaz, Szeptikus Osztaly, Szekesfehervar, Hungary.
   [Jakab, Gabriella] Fejer Varmegyei Szent Gyorgy Egyet Oktato Korhaz, Mikrobiol Lab, Szekesfehervar, Hungary.
   [Hangody, Laszlo] Uzsok Utcai Korhaz, Traumatol Ortopediai Osztaly, Budapest, Hungary.
   [Hangody, Laszlo] Semmelweis Egyet, Altalanos Orvostud Kar, Traumatol Tanszek, Budapest, Hungary.
C3 Semmelweis University
RP Révész, ES (通讯作者)，Neumann J U 21, H-8000 Szekesfehervar, Hungary.
EM revesze1978@gmail.com
CR American Association of Textile Chemists and Colorists, 2019, TM100TM 100 TEST MET
   Berner-Hansen V, 2021, HERNIA, V25, P1481, DOI 10.1007/s10029-021-02485-7
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   Gergely L., 1999, MEDICAL MIKROBIOLOGY
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   National Institute for Health and Care Excellence, SURG SITE INFECT PRE
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   Szentkereszty Zs, 2019, THEORETICAL KNOWLEDG
   Warren JA, 2020, AM J SURG, V220, P751, DOI 10.1016/j.amjsurg.2020.01.028
NR 18
TC 0
Z9 0
U1 0
U2 0
PU AKADEMIAI KIADO ZRT
PI BUDAPEST
PA BUDAFOKI UT 187-189-A-3, H-1117 BUDAPEST, HUNGARY
SN 0030-6002
EI 1788-6120
J9 ORVOSI HETILAP
JI Orvosi Hetilap
PD MAY 3
PY 2026
VL 167
IS 18
BP 714
EP 721
DI 10.1556/650.2026.33543
PG 8
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA HJ3YH
UT WOS:001755455700001
PM 42070235
OA hybrid
DA 2026-07-24
ER

PT J
AU Cozza, V
   Pascale, MM
   Pepe, G
   Panzera, R
   Magalini, S
   Gui, D
AF Cozza, Valerio
   Pascale, Marco M.
   Pepe, Gilda
   Panzera, Rocco
   Magalini, Sabina
   Gui, Daniele
TI Empirical measurement of pressure in negative pressure wound therapy for
   infected wounds: How long can it really stay under pressure?
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID SURGICAL SITE INFECTION
AB Surgical site infections represent one of the most common surgical complications. Negative pressure wound therapy is considered an effective wound management system, based on the principle that a negative pressure inside the wound can suction fluids and approximate wound edges. With the negative pressure wound therapy systems commercially available it is assumed that the pressure inside the wound is stable at the set values. We conducted a prospective experimental study to investigate this. The negative pressure level achieved inside the dressing was investigated at a standard distance from the pad of suction and at specific times in patients with surgical site infections. Pressure measurements were performed in 28 dressings in 14 patients admitted to the Emergency Surgery Department between April 2016 and June 2017. In general, the machine was set at a pressure of -100 mmHg. Negative pressure was measured with a portable pressure reader in the dressing sponge at a distance of 0, 1.5, and 3 cm from the suction pad at the time of dressing change at 24 and 48 hours. The data suggest that there is a significant decrease in negative pressure at both 1.5 and 3 cm from the suction pad at 48 hours from the dressing change (p = 0.0001 and p < 0.0001, respectively). This preliminary study shows with statistical significance that the pressure inside the sponge of a negative pressure wound therapy system decreases after 48 hours, confirming that the pressure inside the system is not the same as the pressure reported by the machine and, instead of being stable, changes overtime.
C1 [Cozza, Valerio; Pascale, Marco M.; Pepe, Gilda; Panzera, Rocco; Magalini, Sabina; Gui, Daniele] Univ Cattolica Sacro Cuore, Fdn Policlin A Gemelli, Emergency Surg Dept, Rome, Italy.
C3 Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli
RP Cozza, V (通讯作者)，Univ Cattolica Sacro Cuore, Ist Clin Chirurg 9B, Largo Francesco Vito 1, I-00168 Rome, Italy.
EM valerio.cozza@gmail.com
RI Pascale, Marco Maria/AAK-5807-2020
OI Pascale, Marco Maria/0000-0003-1355-0207; Panzera, Rocco
   Maria/0000-0001-7015-2964
CR [Anonymous], 2013, MPL115A1
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   Delgado A, 2016, SAGE OPEN MED, V4, DOI 10.1177/2050312115624988
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
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NR 12
TC 2
Z9 3
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD MAR-APR
PY 2019
VL 27
IS 2
BP 190
EP 195
DI 10.1111/wrr.12693
PG 6
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA HP5ND
UT WOS:000461722900006
PM 30548524
DA 2026-07-24
ER

PT J
AU Rose, V
   Haram, NH
   Gallala, S
AF Rose, Victoria
   Haram, Nadine Hachah
   Gallala, Sarah
TI A new portable negative pressure wound therapy device: a prospective
   study investigating clinical outcomes
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE closed incision negative pressure wound therapy; closed surgical
   incision; exudate management; NPWT; single-use negative pressure wound
   therapy system; wound; wound care; wound dressing; wound healing
ID CLOSED INCISION MANAGEMENT; SURGICAL-SITE INFECTION; METAANALYSIS; HIP
AB Objective: Closed surgical incision sites at high risk of complications, and with exudate or leakage, are increasingly being managed with closed incision negative pressure wound therapy (ciNPWT) to reduce tissue stress and increase the force necessary to disrupt the incision. This study was undertaken to investigate the performance and safety of a canister-based, single-use NPWT (suNPWT) system when used on closed surgical incision sites. Method: The investigation was designed as a prospective, open, non-comparative, multicentre study aimed at confirming the safety and performance attributes of the suNPWT system when applied to low-to-moderately exuding closed surgical incisions. The primary performance measure was the wound remaining closed from baseline to the last follow-up visit on day 14. Secondary performance measures included: wound and periwound condition; wear time of the system; product consumption; adherence to therapy; and patients' pain progress. Details of adverse events were also collected. Results: Some 35 patients were recruited. The closed surgical incisions responded well to treatment with the tested suNPWT system. All wounds remained closed throughout the investigation. Consistent with other studies of ciNPWT reporting low infection rates, the current study observed either no or low exudation in 90.4% of wounds at the final visit, together with absence of surgical site infection. Pain severity levels were low, both at dressing change and during delivery of negative pressure. No serious adverse device events were reported. Conclusion: In this study, the suNPWT system supported the healing of closed surgical incisions with no safety concerns relating to its use.
C1 [Rose, Victoria; Haram, Nadine Hachah] Guys & St Thomas Hosp NHS Trust, London, England.
   [Gallala, Sarah] UZ Brussel, Wondklin TAV Valerie Hanssens, Jette, Belgium.
C3 University Hospital Brussels
RP Haram, NH (通讯作者)，Guys & St Thomas Hosp NHS Trust, London, England.
EM Nadine.HachachHaram@gstt.nhs.uk
OI Haram, Nadine/0009-0006-6197-6172; Rose, Victoria/0000-0003-0166-9470
FU Molnlycke Health Care, Sweden
FX The study was sponsored by Molnlycke Health Care, Sweden. The authors
   have no conflicts of interest.
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NR 33
TC 2
Z9 2
U1 0
U2 3
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD NOV
PY 2024
VL 33
IS 11
BP 833
EP 840
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA P5L7G
UT WOS:001378328800005
PM 39480726
DA 2026-07-24
ER

PT J
AU Herczeg, A
   Szijárto, A
   Fülöp, A
   Varga, K
   Marton, J
   Loderer, Z
   Mohos, B
   Páncél, B
   Szendrényi, V
   Lázár, G
   Libor, L
   Káposztás, Z
   Máthé, E
   Bursics, A
   Kecskédi, B
   Sikorszki, L
   Venczel, L
   Bánky, B
AF Herczeg, Andras
   Szijarto, Attila
   Fulop, Andras
   Varga, Krisztina
   Marton, Jozsef
   Loderer, Zoltan
   Mohos, Balazs
   Pancel, Balazs
   Szendrenyi, Vilmos
   Lazar, Gyorgy
   Libor, Laszlo
   Kaposztas, Zsolt
   Mathe, Ervin
   Bursics, Attila
   Kecskedi, Bence
   Sikorszki, Laszlo
   Venczel, Laszlo
   Banky, Balazs
TI Prophylactic Negative Pressure Wound Therapy Reduces Superficial
   Surgical Site Infection Risk of Emergency Surgery Patients: Results of a
   Multicenter Randomised Prospective Clinical Trial
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE emergency surgery; negative pressure wound therapy; prevention; surgical
   site infection
ID PREVENTION; CLOSURE; COMPLICATIONS; LAPAROTOMIES
AB Despite modern aseptic precautions, surgical site infection remains a significant problem. Although the benefits of negative pressure wound therapy in the treatment of chronic wounds are well established, high-level evidence is still lacking on the potential role of negative pressure in the prevention of surgical site infections. We conducted a multicenter, randomised, prospective trial of closed incision vacuum therapy. A total of 90 general surgery patients undergoing emergency laparotomy were enrolled and randomised, 45 cases in the treatment group and 45 cases in the control group. Our aim was to show a significant difference in the rate of surgical site infection between the two groups. In the study group, laparotomy wounds were treated with a single 5-day course of prophylactic vacuum therapy, whereas the control group underwent conventional postoperative wound management with sterile gauze dressings. Ten of the 45 patients in the study group developed a surgical site infection compared to 20 of 45 in the control group (22.2% vs. 44.4% p = 0.025). Upon further analysis, the proportion of superficial SSIs was found to be significantly lower in the ciNPWT group (40% vs. 20% p = 0.038), whereas the difference in deep SSI rates was not statistically significant (4.4% vs. 4.4% p = 1.0). In conclusion, negative pressure wound therapy is not only an effective way to heal chronic wounds, but it's prophylactic use may reduce the overall rate of surgical site infections.Trial Registration: : NCT03716687
C1 [Herczeg, Andras; Szijarto, Attila; Fulop, Andras; Varga, Krisztina; Banky, Balazs] Semmelweis Univ, Dept Surg Transplantat & Gastroenterol, Budapest, Hungary.
   [Varga, Krisztina; Marton, Jozsef; Banky, Balazs] St Borbala Hosp, Dept Surg, Tatabanya, Hungary.
   [Loderer, Zoltan; Mohos, Balazs] Markusovszky Univ Teaching Hosp Vas Cty, Dept Surg, Szombathely, Hungary.
   [Pancel, Balazs; Szendrenyi, Vilmos] St Rokus Hosp, Dept Surg, Baja, Hungary.
   [Lazar, Gyorgy; Libor, Laszlo] Univ Szeged, Surg Clin, Szeged, Hungary.
   [Kaposztas, Zsolt; Mathe, Ervin] Kap Mor Hosp Somogy Cty, Kaposvar, Hungary.
   [Bursics, Attila; Kecskedi, Bence] Uzsoki St Hosp, Dept Surg, Budapest, Hungary.
   [Sikorszki, Laszlo; Venczel, Laszlo] Hosp Bacs Kiskun Cty, Dept Surg, Kecskemet, Hungary.
C3 Semmelweis University; Szeged University
RP Herczeg, A (通讯作者)，Semmelweis Univ, Dept Surg Transplantat & Gastroenterol, Budapest, Hungary.
EM herczeg.andras.ivan@semmelweis.hu
RI /AAL-9676-2020
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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   Banasiewicz T., "Traditional and Single Use NPWT: When to Use and How to Decide on the Appropriate Use? Recommendations of an Expert Panel,"
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NR 25
TC 5
Z9 5
U1 4
U2 5
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUL
PY 2025
VL 22
IS 7
AR e70718
DI 10.1111/iwj.70718
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA F0267
UT WOS:001623128400001
PM 40605477
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Paolini, G
   Sorotos, M
   Firmani, G
   Gravili, G
   Ceci, D
   di Pompeo, FS
AF Paolini, Guido
   Sorotos, Michail
   Firmani, Guido
   Gravili, Gianluca
   Ceci, Diego
   di Pompeo, Fabio Santanelli
TI Low-vacuum negative pressure wound therapy protocol for complex wounds
   with exposed vessels
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE complex wound; exposed vessels; low-vacuum negative pressure wound
   therapy; negative pressure wound therapy; NPWT; treatment protocol;
   wound; wound care; wound dressing; wound healing
ID ASSISTED CLOSURE THERAPY; GROIN; INFECTIONS; GAUZE
AB Objective: Treating high-risk surgical patients with complex wounds over exposed blood vessels is a challenge. Guided wound healing may be the only treatment possible. Negative pressure wound therapy (NPWT) is not recommended in these cases. The authors challenged these current recommendations and share their preliminary experience.
   Method: The authors adapted a NPWT protocol that uses low-vacuum continuous pressure (-80mmHg) with a silicone sheath and gauze/foam dressing between the wound bed and the device. They monitored the clinical features of patients' wounds to detect bleeding/ischaemia early on. Dressings were changed every 72-96 hours.
   Results: This protocol was followed in five male patients (aged 23-68 years) with complex wounds over exposed vessels. Two cases were foot crush injuries, one midfoot amputation, one hand self-subamputation and one vascular bypass infection. Comorbidities included monoarterial limbs/stump, severe arteriopathy and psychiatric disorder. The exposed vessels were femoral, radial and ulnar, anterior and posterior tibial arteries and veins. Mean treatment lasted 37 days (range 20-61 days). No episodes of severe bleeding/ischaemia of the extremities were observed. Treatment was discontinued once debridement was complete and granulation tissue allowed spontaneous closure/grafting. All wounds appeared stable at 1-year follow-up.
   Conclusion: The low-vacuum NPWT protocol was successful in solving five difficult cases. This regimen reduces risks associated with NPWT use on wounds with exposed vessels. The authors believe further validation is required to strengthen the evidence. However, preliminary data are encouraging and might help to change future NPWT recommendations by extending the indications for its use to exposed vessels.
C1 [Paolini, Guido; Firmani, Guido; di Pompeo, Fabio Santanelli] Univ Sapienza Rome, Nesmos Dept, Plast Surg Unit, Fac Med & Psychol, Rome, Italy.
   [Paolini, Guido; Ceci, Diego] St Andrea Hosp Rome, Rome, Italy.
   [Sorotos, Michail] Univ Salerno, PhD Sch Translat Med Dev & Act Aging, Dept Med Surg & Dent, Scuola Med Salernitana, Salerno, Italy.
C3 Sapienza University Rome; Sapienza University Rome; Azienda Ospedaliera
   Sant'Andrea; University of Salerno
RP Paolini, G (通讯作者)，Univ Sapienza Rome, Nesmos Dept, Plast Surg Unit, Fac Med & Psychol, Rome, Italy.; Paolini, G (通讯作者)，St Andrea Hosp Rome, Rome, Italy.
EM guido.paolini@uniroma1.it
RI Firmani, Guido/AAN-4393-2020; SOROTOS, MICHAIL/AAA-9566-2020; paolini,
   guido/F-4707-2012
OI Firmani, Guido/0000-0002-5806-1530; SOROTOS,
   MICHAIL/0000-0002-4822-3794; 
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NR 28
TC 7
Z9 9
U1 0
U2 5
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD JAN
PY 2022
VL 31
IS 1
BP 78
EP 85
DI 10.12968/jowc.2022.31.1.78
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA YU4EW
UT WOS:000751999300010
PM 35077217
DA 2026-07-24
ER

PT J
AU Fernández, LG
AF Fernandez, Luis G.
TI Treatment of Complex Thoracic and Abdominal Trauma Patients: A Review of
   Literature and Negative Pressure Wound Therapy Treatment Options
SO ADVANCES IN WOUND CARE
LA English
DT Review
DE trauma; negative pressure wound therapy; negative pressure wound therapy
   with instillation; closed incision negative pressure therapy; open
   abdomen negative pressure therapy; review
ID DAMAGE CONTROL SURGERY; OPEN ABDOMEN; MANAGEMENT; INSTILLATION; CLOSURE;
   RECOMMENDATIONS; INFECTIONS; FRACTURES; INJURIES; OUTCOMES
AB Significance: In trauma care, extensive surgical intervention may be required. Damage control surgery (DCS) is applicable to patients with life or limb-threatening conditions that are incapable of tolerating a traditional surgical approach.Recent Advances: The current resuscitation strategy for complex trauma patients includes limiting crystalloid fluids, balanced mass transfusion protocols, permissive hypotension, and damage control resuscitation. Recent technological advancements in surgical critical care have improved outcomes in these critically ill patients.Critical Issues: DCS, which is often required in patients with trauma injuries, is typically followed by surgical correction of the injury once the immediate patient survival procedures have been completed. However, DCS and the subsequent injury repair procedures have a high risk for postsurgical complication development.Future Directions: Negative pressure therapy modalities can offer clinicians additional adjunctive and cost-effective tools for the management of the trauma care patient, as these systems can be utilized during both the DCS and the postoperative injury management phases of trauma care.
C1 [Fernandez, Luis G.] Univ Texas Hlth Sci Ctr, Dept Surg, Div Trauma Surg Surg Crit Care, Tyler, TX 75708 USA.
   [Fernandez, Luis G.] Univ Texas Tyler, Sch Med, Bill Barrett Endowed Chair Trauma Surg, Tyler, TX 75799 USA.
C3 University of Texas System; University of Texas-Health Sciences Center
   at Tyler (UTHSCT); University of Texas at Tyler; University of Texas
   System; University of Texas at Tyler
RP Fernández, LG (通讯作者)，Univ Texas Hlth Sci Ctr, Dept Surg, Div Trauma Surg Surg Crit Care, Tyler, TX 75708 USA.; Fernández, LG (通讯作者)，Univ Texas Tyler, Sch Med, Bill Barrett Endowed Chair Trauma Surg, Tyler, TX 75799 USA.
EM thebigkahuna115@gmail.com
RI FERNANDEZ, LUIS/O-7657-2019
OI FERNANDEZ, LUIS/0000-0002-2730-0199
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NR 49
TC 4
Z9 7
U1 1
U2 6
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD AUG 1
PY 2024
VL 13
IS 8
BP 416
EP 423
DI 10.1089/wound.2023.0113
EA OCT 2023
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA A7O0L
UT WOS:001110684700001
PM 37672527
OA hybrid
DA 2026-07-24
ER

PT J
AU Kimura, M
   Nishimura, T
   Kinoshita, O
   Okada, S
   Inafuku, H
   Kyo, S
   Ono, M
AF Kimura, Mitsutoshi
   Nishimura, Takashi
   Kinoshita, Osamu
   Okada, Shuichi
   Inafuku, Hitoshi
   Kyo, Shunei
   Ono, Minoru
TI Successful Treatment of Pump Pocket Infection after Left Ventricular
   Assist Device Implantation by Negative Pressure Wound Therapy and
   Omental Transposition
SO ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
DE pump pocket infection; mediastinitis; negative pressure wound therapy;
   implantable left ventricular assist device; omental transposition
ID POSTSTERNOTOMY MEDIASTINITIS; CLOSURE
AB A 52-year-old man suffering from dilated cardiomyopathy underwent implantable left ventricular assist device (LVAD) insertion as a bridge to transplantation. He presented with evidence of LVAD-related mediastinitis and pump pocket infection 57 days after the LVAD implantation. The mediastinum was reopened and irrigated. A large amount of pus was observed around the outflow and inflow conduits and in the pump pocket. Negative pressure wound therapy (NPWT) was initiated. Methicillin-resistant Staphylococcus aureus (MRSA) was isolated from blood and mediastinal pus. Enterobacter cloacae was also isolated by mediastinal pus culture after the beginning of the NPWT. Three weeks after the start of the NPWT, the pus culture became negative, and omental transposition and sternal closure were performed. Intravenous antibiotics were administered until day 42, with the treatment subsequently switched to oral antibiotics. He was discharged from the hospital on day 57 and followed up at the outpatient clinic. Our findings suggest that NPWT followed by omental transposition be useful to treat mediastinitis or pump pocket infection after implantable LVAD insertion.
C1 [Kimura, Mitsutoshi; Nishimura, Takashi; Kyo, Shunei] Univ Tokyo, Dept Therapeut Strategy Heart Failure, Tokyo 1138655, Japan.
   [Kinoshita, Osamu; Ono, Minoru] Univ Tokyo, Dept Cardiothorac Surg, Tokyo 1138655, Japan.
   [Okada, Shuichi] Gunma Prefectural Cardiovasc Ctr, Div Cardiovasc Surg, Gunma, Japan.
   [Inafuku, Hitoshi] Univ Ryukyus, Div Thorac & Cardiovasc Surg, Nishihara, Okinawa 90301, Japan.
C3 University of Tokyo; University of Tokyo; University of the Ryukyus
RP Nishimura, T (通讯作者)，Univ Tokyo, Dept Therapeut Strategy Heart Failure, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan.
EM takashin-tky@umin.ac.jp
OI Kimura, Mitsutoshi/0009-0007-9071-4400
FU Sun Medical Technology Research Corp. (Nagano, Japan)
FX Mitsutoshi Kimura, Takashi Nishimura, and Shunei Kyo belong to
   Department of Therapeutic Strategy for Heart Failure, which is an
   endowed department sponsored by 13 companies including Sun Medical
   Technology Research Corp. (Nagano, Japan).
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   Shafii AE, 2011, J HEART LUNG TRANSPL, V30, P1421, DOI 10.1016/j.healun.2011.08.007
   Simon D, 2005, CLIN INFECT DIS, V40, P1108, DOI 10.1086/428728
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Topkara VK, 2010, ANN THORAC SURG, V90, P1270, DOI 10.1016/j.athoracsur.2010.04.093
NR 13
TC 18
Z9 20
U1 0
U2 1
PU MEDICAL TRIBUNE INC
PI TOKYO
PA ED COMM ANNALS THORACIC CARDIOVASCULAR SURG, 2-1-30 KUDAN MINAMI,
   CHIYODA-KU, TOKYO, 102-0074, JAPAN
SN 1341-1098
J9 ANN THORAC CARDIOVAS
JI Ann. Thorac. Cardiovasc. Surg.
PY 2014
VL 20
SU S
BP 842
EP 845
DI 10.5761/atcs.cr.12.02192
PG 4
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA AZ1AO
UT WOS:000347973000110
PM 23535582
OA gold
DA 2026-07-24
ER

PT J
AU Ali, M
   Reda, FM
   Issaoui, H
   Abbassi, H
   Gargouri, M
   Razanabola, F
AF Ali, Mazen
   Reda, Fekhaoui Mohammed
   Issaoui, Hichem
   Abbassi, Hatem
   Gargouri, Mahdi
   Razanabola, Fredson
TI Management of a High-Energy Soft Tissue Injury of the Lower Extremity
   Using Negative Pressure Wound Therapy With Instillation and Dwell Time
   and a Reticulated Open Cell Foam Dressing: A Case Report
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE negative pressure wound therapy with instillation and dwell time; NPWT;
   debridement; necrotic tissue
AB Introduction. Soft tissue injuries of the lower extremity are the result of high-energy trauma, such as road accidents, and remain challenging for most orthopedic surgeons. Proper selection of the treatment is important considering the risk of delayed necrosis and wound sepsis. Negative pressure wound therapy (NPWT) has improved complex wound treatment since 1997, but all treatments present advantages and limits. Case Report. A 21-year-old male presented with a high-energy soft tissue injury of the lower extremity. Three days after surgical debridement, complete skin necrosis developed. Successive surgical debridement was done in combination with traditional NPWT for 2 weeks; yet the wound did not progress toward healing, and the bone remained exposed. Negative pressure wound therapy with instillation and dwell time (NPWTi-d) was used with a novel reticulated open cell foam dressing (ROCF-CC) because further surgical debridement was not possible, and the use of NPWT was not recommended by the French high authority for health. Growth of granulation tissue was fast (9 days), even over the bone, without any surgical debridement and despite the presence of nonviable and fibrinous tissue. After that, traditional NPWT was discontinued and a split-thickness skin graft then was used to cover the defects. Four weeks following the accident, all wounds were completely healed. Conclusions. Surgical debridement remains irreplaceable; however, when debridement is not feasible, NPWTi-d with ROCF-CC might be the treatment of choice. This strategy allowed the authors to ensure coverage of an extensive loss of soft tissue when the traditional NPWT limit was reached.
C1 [Ali, Mazen; Issaoui, Hichem; Abbassi, Hatem; Gargouri, Mahdi; Razanabola, Fredson] Reg Hosp Orleans, Dept Orthoped Surg & Trauma, Orleans, France.
   [Reda, Fekhaoui Mohammed] Mohammed V Univ Rabat, Ibn Sina Univ Hosp, Fac Med, Dept Trauma & Orthopaed Surg, Rabat, Morocco.
C3 Centre Hospitalier Universitaire d'Orleans; Mohammed V University in
   Rabat; Ibn sina University Hospital Center of Rabat
RP Reda, FM (通讯作者)，Mohammed V Univ Rabat, Ibn Sina Univ Hosp, Fac Med Rabat, Rabat 10100, Morocco.
EM rfekhaoui@icloud.com
CR Arnez ZM, 2010, J PLAST RECONSTR AES, V63, P1865, DOI 10.1016/j.bjps.2009.11.029
   Barla M, 2017, ORTHOP TRAUMATOL-SUR, V103, P971, DOI 10.1016/j.otsr.2017.05.022
   Blome-Eberwein S, 2018, Burns Open, V2, P208, DOI [10.1016/j.burnso.2018.05.004, 10.1016/j.burnso.2018.05.004, DOI 10.1016/J.BURNSO.2018.05.004]
   HAS, 2012, Ann Dermatol Venereol, V139, P753, DOI 10.1016/j.annder.2012.07.005
   Kim PJ, 2018, WOUNDS, pS1
   Liu DX, 2012, J TRAUMA ACUTE CARE, V73, P209, DOI 10.1097/TA.0b013e31824bac22
   Matthews MR, 2018, CUREUS J MED SCIENCE, V10, DOI 10.7759/cureus.3632
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   Téot L, 2017, INT WOUND J, V14, P842, DOI 10.1111/iwj.12719
NR 11
TC 5
Z9 6
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD DEC
PY 2020
VL 32
SU S
BP 375
EP 377
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA SR8KO
UT WOS:000661294500004
PM 33472165
DA 2026-07-24
ER

PT J
AU Shi, JZ
   Zhai, X
   Li, JH
   Xue, CY
   Bi, HD
AF Shi Jia-zi
   Zhai Xiao
   Li Jun-hui
   Xue Chun-yu
   Bi Hong-da
TI Negative pressure wound therapy combined with skin grafting improves
   surgical wound healing in the perianal area
SO MEDICINE
LA English
DT Article
DE negative pressure wound therapy; perianal tumor; perianal wound; skin
   grafting
ID OF-THE-LITERATURE; PAGETS-DISEASE; EXCISION; DEFECTS; RECONSTRUCTION;
   MANAGEMENT; REPAIR; FLAPS
AB Management of large tissue defects resulting from local wide resection of perianal is a clinical challenge for surgeons. The aim of the present study was to investigate the efficacy of negative pressure wound therapy (NPWT) following skin grafting on perianal surgical wound healing.Included in this study were 12 patients with perianal tumors who received skin grafting after perianal tumor resection between December 2012 and December 2014. A self-designed negative pressure drainage device was then applied to maintain a standard negative pressure at -150mm Hg and removed on day 8 postoperation. The outcome was recorded immediately after NPWT and at 6-month follow-up.All skin grafts survived without infection, hematoma, and necrosis in all 12 patients. No tumor recurrence was detected during 6-month follow-up. Natural folds were observed around the anus. All patients showed normal bowel movements.NPWT following skin grafting was effective for perianal surgical wound healing and infection prevention, thus benefiting anatomical and functional recovery of the anus.
C1 [Shi Jia-zi; Zhai Xiao] Second Mil Med Univ, Grad Management Unit, Shanghai, Peoples R China.
   [Li Jun-hui; Xue Chun-yu; Bi Hong-da] Second Mil Med Univ, Changhai Hosp, Dept Plast Surg, 168 Changhai Rd, Shanghai 200433, Peoples R China.
C3 Naval Medical University; Naval Medical University
RP Li, JH; Xue, CY; Bi, HD (通讯作者)，Second Mil Med Univ, Changhai Hosp, Dept Plast Surg, 168 Changhai Rd, Shanghai 200433, Peoples R China.
EM lissot@163.com; xcyfun@sina.com; bihongda0411@163.com
CR Conklin A, 2009, J GASTROINTEST SURG, V13, P951, DOI 10.1007/s11605-009-0822-x
   Delaunoit T, 2004, ACTA GASTRO-ENT BELG, V67, P228
   Fujii M, 2007, J PLAST RECONSTR AES, V60, P1208, DOI 10.1016/j.bjps.2007.02.005
   Gupta S, 2012, INT WOUND J, V9, P40, DOI 10.1111/j.1742-481X.2012.01019.x
   Hassan I, 2001, AM J SURG, V181, P363, DOI 10.1016/S0002-9610(01)00578-5
   Kishi K, 2010, J PLAST RECONSTR AES, V63, P1353, DOI 10.1016/j.bjps.2009.06.022
   Kyriazanos ID, 2011, SURG ONCOL, V20, pE61, DOI 10.1016/j.suronc.2010.09.005
   Lam DTY, 2001, DIS COLON RECTUM, V44, P868, DOI 10.1007/BF02234711
   Mermerkaya U, 2016, INT WOUND J, V13, P394, DOI 10.1111/iwj.12318
   Minicozzi A, 2010, INT J COLORECTAL DIS, V25, P1, DOI 10.1007/s00384-009-0797-9
   Möller MG, 2014, AM J SURG, V207, P485, DOI 10.1016/j.amjsurg.2013.04.005
   St Peter SD, 2004, AM J SURG, V187, P413, DOI 10.1016/j.amjsurg.2003.12.021
NR 12
TC 7
Z9 10
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD AUG
PY 2016
VL 95
IS 35
AR e4670
DI 10.1097/MD.0000000000004670
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA DX0HC
UT WOS:000384041400050
PM 27583890
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Hansen, F
   Aldrich, A
   Dorneden, A
   Esce, A
   Spafford, M
   Syme, N
   Olson, G
   Boyd, N
AF Hansen, Frederick
   Aldrich, Abigale
   Dorneden, Ashley
   Esce, Antoinette
   Spafford, Michael
   Syme, Noah
   Olson, Garth
   Boyd, Nathan
TI Negative Pressure Wound Therapy: A Novel Technique for Treatment of
   Chylous Fistula After Neck Surgery
SO ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
LA English
DT Article
DE chylous fistula; chyle leak; wound vac therapy; negative pressure wound
   therapy; postoperative complications; neck dissection
ID MANAGEMENT; OCTREOTIDE; DISSECTION
AB Objectives: Chylous fistula or "chyle leak" is a rare complication of head and neck surgery that can be exceedingly difficult to manage. Traditional treatments include pressure dressings, dietary modification, octreotide administration, closed suction drainage, and revision surgery. In 2017, the Otolaryngology team at the University of New Mexico Hospital (UNMH) began implementing negative pressure wound therapy (NPWT) in conjunction with traditional conservative measures to treat chylous fistula. From our initial experiences implementing NPWT, an optimized protocol was developed and is now routinely used to manage chyle leaks at our institution.Methods: A retrospective chart review was performed to identify all patients who were treated with negative pressure wound therapy at UNMH after undergoing neck surgery and developing a chylous fistula. These patients were compared to a control group of patients with chylous fistula who were treated with traditional approaches alone before NPWT was implemented at UNMH.Results: Twenty-six patients were treated with NPWT for their chyle leak after neck surgery, 10 as part of the original protocol (Protocol 1) and 16 under an improved methodology (Protocol 2). No instances of great vessel desiccation were observed in any patient treated with NPWT. Protocol 2 was found to significantly reduce hospital length of stay as well as to reduce the duration of octreotide administration, dietary modification, and drain device placement compared to the control group treated by historical methods.Conclusion: NPWT is a novel and effective treatment approach that can be used in addition to traditional treatment modalities to treat chylous fistulae after neck surgery.
C1 [Hansen, Frederick; Aldrich, Abigale] Univ New Mexico, Sch Med, Albuquerque, NM USA.
   [Dorneden, Ashley; Esce, Antoinette; Spafford, Michael; Syme, Noah; Olson, Garth; Boyd, Nathan] Univ New Mexico, Sch Med, Dept Surg, Otolaryngol Div, 2211 Lomas Blvd NE, Albuquerque, NM 87106 USA.
C3 University of New Mexico; University of New Mexico
RP Boyd, N (通讯作者)，Univ New Mexico, Sch Med, Dept Surg, Otolaryngol Div, 2211 Lomas Blvd NE, Albuquerque, NM 87106 USA.
EM nhboyd@salud.unm.edu
RI ; Esce, Antoinette/ACS-1479-2022
OI Esce, Antoinette/0000-0001-7637-9641; Syme, Noah/0000-0002-7953-1765;
   Alich, Abigale/0009-0006-2583-4169
CR Ahn D, 2015, ANN SURG ONCOL, V22, pS1000, DOI 10.1245/s10434-015-4822-7
   Bai YC, 2021, J INT MED RES, V49, DOI 10.1177/03000605211021375
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NR 17
TC 0
Z9 0
U1 0
U2 2
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0003-4894
EI 1943-572X
J9 ANN OTO RHINOL LARYN
JI Ann. Otol. Rhinol. Laryngol.
PD JAN
PY 2026
VL 135
IS 1
BP 59
EP 67
DI 10.1177/00034894251361983
EA AUG 2025
PG 9
WC Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology
GA T3845
UT WOS:001552298000001
PM 40826903
OA Bronze
DA 2026-07-24
ER

PT J
AU Zhao, YA
   Frei, F
   Kalbas, Y
   Pape, HC
   Jukema, GN
AF Zhao, Yina
   Frei, Flurina
   Kalbas, Yannik
   Pape, Hans-Christoph
   Jukema, Gerrolt N.
TI Long term experiences with negative pressure wound therapy in
   combination with polyhexanid solution instillation technique for
   treatment of posttraumatic infections and osteomyelitis
SO LANGENBECKS ARCHIVES OF SURGERY
LA English
DT Article
DE Negative pressure wound therapy; Negative pressure polyhexanid
   instillation technique; posttraumatic osteomyelitis; posttraumatic
   infection
ID ANTISEPTIC SOLUTION; PSEUDOMONAS-PUTIDA; PROTEUS; IMPACT; SALINE; FOAM
AB Purpose This retrospective study assessed the effectiveness of Negative Pressure Wound Therapy with Instillation using polyhexanide 0.2% solution for treating infected chronic trauma-related wounds, open fractures, and posttraumatic osteomyelitis. Methods A total of 67 patients (2014-2024) were categorized into posttraumatic osteomyelitis (N = 27), open fractures (N = 23), and soft tissue infections/trauma wounds (N = 17). The therapy combined surgical debridement and vacuum-assisted dressing with intermittent polyhexanide 0.2% instillation. Foam dressings were changed every 3-4 days, with concurrent antibiotic therapy. Results Statistical analysis showed significant reductions in bacterial specimens (99 to 20, p < 0.001), and a low reinfection of 10.2% in osteomyelitis and open fracture, which is lower compared to standard treatments (debridement, lavage and antibiotic loaded beads). The average treatment was 12.6 days with 3.22 dressing changes, with variations between the groups. CRP (C-reactive protein) levels significantly decreased from start to follow-up (p = 0.014). Over half of the cases achieved delayed primary closure, with osteomyelitis showing a longer duration of antibiotic therapy compared to the other groups. The most common risk factors were cardiovascular conditions, with an average of 3.17 risk factors per patient. Conclusion While limited by its retrospective design and small sample size, this study provides a basis to hypothesize that Negative Pressure Wound Therapy with Instillation can be an effective adjunctive method in reducing bacterial load, may accelerate wound closure and lower infection recurrence, particularly for osteomyelitis and orthopaedic implant infections.
C1 [Zhao, Yina; Frei, Flurina; Kalbas, Yannik; Pape, Hans-Christoph; Jukema, Gerrolt N.] Univ Hosp Zurich, Dept Traumatol, Zurich, Switzerland.
C3 University of Zurich; University Zurich Hospital
RP Zhao, YA (通讯作者)，Univ Hosp Zurich, Dept Traumatol, Zurich, Switzerland.
EM yina.zhao@usz.ch
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NR 34
TC 0
Z9 0
U1 1
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1435-2443
EI 1435-2451
J9 LANGENBECK ARCH SURG
JI Langenbecks Arch. Surg.
PD APR 25
PY 2026
VL 411
IS 1
AR 158
DI 10.1007/s00423-026-04061-y
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA JF8FT
UT WOS:001788310100002
PM 42034684
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Jia, B
   Xue, R
   Li, J
   Guo, JC
   Liu, JN
AF Jia, Bei
   Xue, Rui
   Li, Jia
   Guo, Jichao
   Liu, Jianning
TI Novel insights into vancomycin-loaded calcium sulfate and negative
   pressure wound therapy in preventing infections in open fractures
SO JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
LA English
DT Article
DE Open fractures; Staphylococcus aureus infections; Vancomycin-Loaded
   Calcium Sulfate; Negative pressure wound therapy; Macrophage
   polarization; M2
AB BackgroundOpen fractures are challenging due to susceptibility to Staphylococcus aureus infections. This study examines the impact of Vancomycin-Loaded Calcium Sulfate (VLCS) and negative pressure wound therapy (NPWT) on macrophage behavior in enhancing healing and infection resistance. Both VLCS and NPWT were evaluated individually and in combination to determine their effects on macrophage polarization and infection resistance in open fractures.MethodsThrough single-cell RNA sequencing, genomic expressions in macrophages from open fracture patients treated with VLCS and NPWT were compared to a control group. The analysis focused on MBD2 gene changes related to macrophage polarization.ResultsRemarkable modifications in MBD2 expression in the treatment group indicate a shift towards M2 macrophage polarization. Additionally, the combined treatment group exhibited greater improvements in infection resistance and healing compared to the individual treatments. This shift suggests a healing-promoting atmosphere with improved infection resilience.ConclusionsVLCS and NPWT demonstrate the ability to alter macrophage behavior toward M2 polarization, which is crucial for infection prevention in open fractures. The synergistic effect of their combined use shows even greater promise in enhancing outcomes in orthopedic trauma care.
C1 [Jia, Bei] Hebei Med Univ, Hosp 1, Nosocomial Infect Management Dept, 89 Donggang Rd, Shijiazhuang, Peoples R China.
   [Xue, Rui; Li, Jia; Guo, Jichao; Liu, Jianning] Hebei Med Univ, Hosp 3, Dept Orthopaed Surg, 139 ZiQiang Rd, Shijiazhuang, Hebei, Peoples R China.
C3 Hebei Medical University; Hebei Medical University
RP Liu, JN (通讯作者)，Hebei Med Univ, Hosp 3, Dept Orthopaed Surg, 139 ZiQiang Rd, Shijiazhuang, Hebei, Peoples R China.
EM 37900477@hebmu.edu.cn
FU National Outstanding Youth Science Fund Project of National Natural
   Science Foundation of China
FX None.
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NR 41
TC 1
Z9 2
U1 2
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-799X
J9 J ORTHOP SURG RES
JI J. Orthop. Surg. Res.
PD AUG 29
PY 2024
VL 19
IS 1
AR 517
DI 10.1186/s13018-024-04931-5
PG 16
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA E0F3O
UT WOS:001299846100001
PM 39198853
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Roberson, JL
   Butt, Z
   Florez-Pollack, S
   Morgan, E
   Rosenbach, M
   Braslow, BM
   Yelon, JA
AF Roberson, Jeffrey L.
   Butt, Zoya
   Florez-Pollack, Stephanie
   Morgan, Eric
   Rosenbach, Misha
   Braslow, Benjamin M.
   Yelon, Jay A.
TI An Intensive Multidisciplinary Approach in Management of Extensive
   Nonuremic Calciphylaxis of the Bilateral Lower Extremities with
   Angioinvasive Fungus and Mold
SO JOURNAL OF BURN CARE & RESEARCH
LA English
DT Article
ID HYPOCHLOROUS ACID; RISK-FACTORS; COHORT
AB Management of infected wounds related to calciphylaxis poses a significant clinical challenge with high morbidity and mortality. Given no definitive management guidelines exist specific to nonuremic calciphylaxis, multiple modalities including sodium thiosulfate, antibiotics, hyperbaric oxygen therapy, and surgical debridement with wound care must be considered. When occurring over a large surface area, standard daily dressing changes are especially labor intensive, inefficient, and ineffective. Negative pressure wound therapy with instillation and dwell time offers broad wound coverage with ongoing therapeutic benefit. We present the case of a previously healthy 19-year-old woman who was transferred for tertiary level care of extensive nonuremic calciphylaxis wounds of the bilateral lower extremities complicated by angioinvasive coinfection with fungus and mold that was managed with a multidisciplinary approach of intensive medical management, aggressive surgical debridement, and negative pressure wound therapy with instillation of hypochlorous acid solution. Ultimately, she achieved full granulation and wound coverage with skin grafting. Large area, infected wounds related to nonuremic calciphylaxis can be successfully managed with multidisciplinary medical management, aggressive surgical debridement, and negative pressure wound therapy that can instill and dwell hypochlorous acid solution.
C1 [Roberson, Jeffrey L.; Butt, Zoya] Hosp Univ Penn, Dept Surg, Philadelphia, PA USA.
   [Florez-Pollack, Stephanie; Rosenbach, Misha] Hosp Univ Penn, Dept Dermatol, Philadelphia, PA USA.
   [Morgan, Eric] Hosp Univ Penn, Dept Pathol, Philadelphia, PA USA.
   [Morgan, Eric] Hosp Univ Penn, Lab Med, Philadelphia, PA USA.
   [Braslow, Benjamin M.; Yelon, Jay A.] Hosp Univ Penn, Div Trauma, Surg Crit Care & Emergency Surg, Dept Surg, Philadelphia, PA USA.
   [Roberson, Jeffrey L.] Hosp Univ Penn, Dept Surg, 3400 Spruce St,4 Maloney, Philadelphia, PA 19104 USA.
C3 University of Pennsylvania; University of Pennsylvania; University of
   Pennsylvania; University of Pennsylvania; University of Pennsylvania;
   University of Pennsylvania
RP Roberson, JL (通讯作者)，Hosp Univ Penn, Dept Surg, 3400 Spruce St,4 Maloney, Philadelphia, PA 19104 USA.
EM jeffrey.roberson@pennmedicine.upenn.edu
RI Morgan, Eric/NEU-1212-2025
OI Florez-Pollack, Stephanie/0000-0002-5959-0856; Yelon,
   Jay/0000-0001-7980-8042
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NR 21
TC 2
Z9 3
U1 0
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1559-047X
EI 1559-0488
J9 J BURN CARE RES
JI J. Burn Care Res.
PD JAN 5
PY 2023
VL 44
IS 1
BP 218
EP 221
DI 10.1093/jbcr/irac158
EA OCT 2022
PG 4
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA 7S7CQ
UT WOS:000886364500001
PM 36269818
DA 2026-07-24
ER

PT J
AU Pagani, NR
   Moverman, MA
   Puzzitiello, RN
   Menendez, ME
   Kavolus, JJ
AF Pagani, Nicholas R.
   Moverman, Michael A.
   Puzzitiello, Richard N.
   Menendez, Mariano E.
   Kavolus, Joseph J.
TI The Cost-Effectiveness of Closed Incisional Negative Pressure Wound
   Therapy for Infection Prevention after Revision Total Knee Arthroplasty
SO JOURNAL OF KNEE SURGERY
LA English
DT Article
DE prosthetic joint infection; revision; total knee arthroplasty; cost;
   negative pressure wound therapy
ID TOTAL HIP; COMPLICATIONS; SURGERY; DRESSINGS; DRAINAGE; BURDEN
AB Recent investigations have shown that closed incisional negative pressure wound therapy (ciNPWT) decreases the rate of postoperative wound complications following revision total knee arthroplasty (TKA). In this study, we used a break-even analysis to determine whether ciNPWT is a cost-effective measure for reducing prosthetic joint infection (PJI) after revision TKA. The cost of ciNPWT, cost of treatment for PJI, and baseline infection rates following revision TKA were collected from institutional data and the literature. The absolute risk reduction (ARR) in infection rate necessary for cost-effectiveness was calculated using break-even analysis. Using our institutional cost of ciNPWT ($600), this intervention would be cost-effective if the initial infection rate of revision TKA (9.0%) has an ARR of 0.92%. The ARR needed for cost-effectiveness remained constant across a wide range of initial infection rates and declined as treatment costs increased. The use of ciNPWT for infection prevention following revision TKA is cost-effective at both high and low initial infection rates, across a broad range of treatment costs, and at inflated product expenses.
C1 [Pagani, Nicholas R.; Moverman, Michael A.; Puzzitiello, Richard N.; Menendez, Mariano E.; Kavolus, Joseph J.] Tufts Med Ctr, Dept Orthopaed Surg, 800 Washington St, Boston, MA 02111 USA.
C3 Tufts Medical Center
RP Pagani, NR (通讯作者)，Tufts Med Ctr, Dept Orthopaed Surg, 800 Washington St, Boston, MA 02111 USA.
EM npagani@tuftsmedicalcenter.org
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NR 42
TC 3
Z9 3
U1 0
U2 2
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 1538-8506
EI 1938-2480
J9 J KNEE SURG
JI J. Knee Surg.
PD OCT
PY 2022
VL 35
IS 12
BP 1301
EP 1305
DI 10.1055/s-0041-1724137
EA JAN 2021
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 5E3KB
UT WOS:000612582100008
PM 33511588
DA 2026-07-24
ER

PT J
AU Leong, S
   Lo, ZJ
AF Leong, SzeWai
   Lo, Zhiwen Joseph
TI Use of disposable negative pressure wound therapy on split-thickness
   skin graft recipient sites for peripheral arterial disease foot wounds:
   A case report
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE disposable negative pressure wound therapy; mechanically powered
   negative pressure wound device; SNAP therapy; split-thickness skin graft
AB Split-thickness skin graft (STSG) helps to promote healing of wounds by providing a viable soft tissue cover. However, the success of which is influenced by how well it takes to the recipient site. Studies have demonstrated that negative pressure wound therapy (NPWT) is an excellent modality to promote graft survival. Technological advancements have made possible the invention of disposable, ultraportable, and mechanically operated versions for improved user experience. Alas, little has been discussed about their benefits on STSG. Therefore, the purpose of this case report is to highlight the effective use of disposable NPWT on freshly applied STSG. We report here a novel use of the disposable NPWT (SNAP therapy system) for STSG recipient sites in two patients with peripheral arterial disease (PAD) foot wounds. In both patients, there was 100% STSG uptake, and the lightweight disposable NPWT system makes for a more cost-effective and comfortable experience for patients. Disposable NPWT may be a feasible alternative to conventional NPWT to aid with STSG uptake for PAD foot wound recipient sites.
C1 [Leong, SzeWai; Lo, Zhiwen Joseph] Tan Tock Seng Hosp, Gen Surg Dept, Vasc Surg Serv, Singapore, Singapore.
C3 Tan Tock Seng Hospital
RP Leong, S (通讯作者)，Block 5,Delta Ave 06-13, Singapore, Singapore.
EM szewai.leong@mohh.com.sg
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NR 14
TC 5
Z9 7
U1 0
U2 5
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2020
VL 17
IS 3
BP 716
EP 721
DI 10.1111/iwj.13291
EA FEB 2020
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA LH4PB
UT WOS:000514228900001
PM 32073214
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Roos, E
   Toso, C
   Meyer, J
AF Roos, Elin
   Toso, Christian
   Meyer, Jeremy
TI Comment on "Meta-analysis, Meta-regression, and GRADE Assessment of
   Randomized and Nonrandomized Studies of Incisional Negative Pressure
   Wound Therapy Versus Control Dressings for the Prevention of
   Postoperative Wound Complications''
SO ANNALS OF SURGERY
LA English
DT Letter
ID SURGICAL SITE INFECTIONS; GENERAL-SURGERY; RISK; LAPAROTOMY
C1 [Roos, Elin] Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden.
   [Toso, Christian; Meyer, Jeremy] Univ Hosp Geneva, Div Digest Surg, Geneva, Switzerland.
   [Toso, Christian; Meyer, Jeremy] Univ Geneva, Unit Surg Res, Geneva, Switzerland.
C3 Karolinska Institutet; University of Geneva; University of Geneva
RP Meyer, J (通讯作者)，Univ Hosp Geneva, Div Digest Surg, Geneva, Switzerland.; Meyer, J (通讯作者)，Univ Geneva, Unit Surg Res, Geneva, Switzerland.
EM jeremy.meyer@hcuge.ch
RI Meyer, Jeremy/AAP-3367-2020; Toso, Christian/E-7785-2018
OI Meyer, Jeremy/0000-0003-3381-9146; Toso, Christian/0000-0003-1652-4522;
   Meyer, Elin Roos/0000-0002-8275-2702
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NR 25
TC 2
Z9 2
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0003-4932
EI 1528-1140
J9 ANN SURG
JI Ann. Surg.
PD DEC
PY 2021
VL 274
IS 6
BP E698
EP E699
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WX3XK
UT WOS:000718532600074
PM 32068558
DA 2026-07-24
ER

PT J
AU Ou, KL
   Tzeng, YS
   Liu, HH
   Wu, CJ
   Chen, CY
   Chou, YY
   Hsu, KF
   Wang, CH
   Dai, NT
   Chang, CK
AF Ou, Kuang-Ling
   Tzeng, Yuan-Sheng
   Liu, Hung-Hui
   Wu, Chien-Ju
   Chen, Chun-Yu
   Chou, Yu-Yu
   Hsu, Kuo-Feng
   Wang, Chih-Hsin
   Dai, Niann-Tzyy
   Chang, Chun-Kai
TI Negative Pressure Wound Therapy in Conjunction With Artificial Dermis
   for Burned Hand Reconstruction
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE negative pressure wound therapy; burns; hand; artificial dermis
ID SUBSTITUTION; CONTRACTURE; INTEGRA
AB Introduction
   Proper wound care along with the use of skin grafts over deep burn wounds has been the standard treatment. However, the goal in burn wound care has shifted from achieving a satisfactory survival rate to improving long-term form and function of the healed wound, which is sometimes hindered by scar contracture. This has prompted surgeons to find alternative ways to treat burn wounds without compromising function. Among burn cases, hand injuries are the most problematic when it comes to delicate function recovery. Methods
   This study presents the results of conjunctive use of a bilayer artificial dermis, negative pressure wound therapy, and split-thickness skin grafts for grafting over acute burn wounds and scar-releasing defects after severe hand burns. Results
   Three months after the operation, the scar was soft and pliable, the aesthetic outcome was good, and the patients gained much improvement in hand function and quality oflife. Conclusions
   The combined technique achieved a good scar quality and aesthetic effect on burned hands as well as excellent functional outcome, which resulted in major improvements and an independent life for the patient.
C1 [Ou, Kuang-Ling] Univ Southern Calif, Keck Sch Med, Dept Pathol, Los Angeles, CA 90007 USA.
   [Ou, Kuang-Ling] Univ Southern Calif, Ostrow Sch Dent, Los Angeles, CA 90007 USA.
   [Ou, Kuang-Ling; Tzeng, Yuan-Sheng; Liu, Hung-Hui; Wu, Chien-Ju; Chen, Chun-Yu; Chou, Yu-Yu; Hsu, Kuo-Feng; Wang, Chih-Hsin; Dai, Niann-Tzyy; Chang, Chun-Kai] Natl Def Med Ctr, Triserv Gen Hosp, Dept Surg, Div Plast & Reconstruct Surg, Taipei, Taiwan.
   [Chou, Yu-Yu; Chang, Chun-Kai] Kaohsiung Armed Forces Gen Hosp, Dept Surg, Zuoying Branch, 553 Junxiao Rd, Kaohsiung 813, Taiwan.
C3 University of Southern California; University of Southern California;
   National Defense Medical University; Tri-Service General Hospital
RP Chang, CK (通讯作者)，Kaohsiung Armed Forces Gen Hosp, Dept Surg, Zuoying Branch, 553 Junxiao Rd, Kaohsiung 813, Taiwan.
EM psdrkai@gmail.com
RI Tzeng, Yuan-sheng/AAD-8843-2020
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NR 16
TC 5
Z9 9
U1 0
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD FEB
PY 2021
VL 86
IS 2S
SU 1
BP S13
EP S17
DI 10.1097/SAP.0000000000002676
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA SK9MG
UT WOS:000656542200003
PM 33438950
DA 2026-07-24
ER

PT J
AU Huang, GS
   Xu, KC
AF Huang, Gao-Shi
   Xu, Ke-Chen
TI Application of negative pressure wound therapy after skin grafting in
   the treatment of skin cancer: A case report
SO WORLD JOURNAL OF CLINICAL CASES
LA English
DT Article
DE Skin cancer; Negative pressure wound therapy; Skin grafting; Case report
AB BACKGROUNDSkin cancer is a common malignant tumor in dermatology. A large area must be excised to ensure a negative incisal margin on huge frontotemporal skin cancer, and it is difficult to treat the wound. In the past, treatment with skin grafting and pressure dressing was easy to cause complications such as wound infections, subcutaneous effusion, skin necrosis, and contracture. Negative pressure wound therapy (NPWT) has been applied to treat huge frontotemporal skin cancer.CASE SUMMARYHerein, we report the case of a 92-year-old woman with huge frontotemporal skin cancer. The patient presented to the surgery department complaining of ruptured bleeding and pain in a right frontal mass. The tumor was pathologically diagnosed as highly differentiated squamous cell carcinoma. The patient underwent skin cancer surgery and skin grafting, after which NPWT was used. She did not experience a relapse during the three-year follow-up period.CONCLUSIONNPWT is of great clinical value in the postoperative treatment of skin cancer. It is not only inexpensive but also can effectively reduce the risk of surgical effusion, infection, and flap necrosis.
C1 [Huang, Gao-Shi] Wuyi First Peoples Hosp, Dept Surg, Wuyi 321200, Zhejiang, Peoples R China.
   [Xu, Ke-Chen] Wuyi First Peoples Hosp, Clin Lab, 2 Nanmen St, Wuyi 321200, Zhejiang, Peoples R China.
RP Xu, KC (通讯作者)，Wuyi First Peoples Hosp, Clin Lab, 2 Nanmen St, Wuyi 321200, Zhejiang, Peoples R China.
EM 8015059@zju.edu.cn
RI Xu, Kechen/MGB-6985-2025
OI Xu, Kechen/0000-0001-5634-2534
CR Faust E, 2021, PLAST RECONSTR SURG, V147, p16S, DOI 10.1097/PRS.0000000000007607
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NR 10
TC 0
Z9 0
U1 0
U2 3
PU BAISHIDENG PUBLISHING GROUP INC
PI PLEASANTON
PA 7041 Koll Center Parkway, Suite 160, PLEASANTON, CA, UNITED STATES
SN 2307-8960
J9 WORLD J CLIN CASES
JI World J. Clin. Cases
PD OCT 6
PY 2023
VL 11
IS 28
BP 6812
EP 6816
DI 10.12998/wjcc.v11.i28.6812
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA X9CR9
UT WOS:001101354800017
PM 37901026
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Jones, EG
   El-Zawahry, AM
AF Jones, Elizabeth Geiger
   El-Zawahry, Ahmed M.
TI Curative Treatment Without Surgical ReconstructionaAftr Perineal
   Debridement of Fournier's Gangrene
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
ID HYPERBARIC-OXYGEN; MANAGEMENT; THERAPY
AB BACKGROUND: Fournier's gangrene (necrotizing fasciitis) is an acute life-threatening disease of the perineal area that requires urgent medical intervention. Once the affected area is surgically debrided and the patient is stabilized, surgical management typically involves 1 or more additional procedures that may include split-thickness skin grafts, flaps, or an elective diverting urostomy and/or colostomy. The professional literature discussing nonsurgical approaches to healing for Fournier's gangrene after surgical debridement is sparse.
   CASE: We present 3 cases of male patients with Fournier's gangrene from our facility who healed uneventfully with negative pressure wound therapy placed after extensive debridement without further surgical intervention. An added benefit was a satisfactory aesthetic effect.
   CONCLUSION: Expert wound management including negative pressure wound therapy after surgical debridement of Fournier's gangrene eliminated the need for further operative procedures and prolonged hospitalizations in these cases. We believe that surgical teams should consider using negative pressure wound therapy as part of the initial curative plan of care after debridement, and that plans for restorative plastic surgery should be restricted to patients who do not exhibit adequate improvement with conservative wound management.
C1 [El-Zawahry, Ahmed M.] Med Univ S Carolina, Charleston, SC USA.
   [El-Zawahry, Ahmed M.] Ralph H Johnson VA Med Ctr, Dept Urol, Charleston, SC 29401 USA.
C3 Medical University of South Carolina; US Department of Veterans Affairs;
   Veterans Health Administration (VHA); Ralph H Johnson VA Medical Center
EM Gwammyliz@heavi.tv
RI El-Zawahry, Ahmed/ABD-8024-2020
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NR 15
TC 5
Z9 8
U1 0
U2 8
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JAN-FEB
PY 2012
VL 39
IS 1
BP 98
EP 102
DI 10.1097/WON.0b013e31823fe212
PG 5
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 881OY
UT WOS:000299497200012
PM 22237647
DA 2026-07-24
ER

PT J
AU Zheng, BY
   Xu, G
   Jiang, H
   Duan, CW
   Liu, X
AF Zheng Biyao
   Xu Gang
   Jiang Hai
   Duan Chenwang
   Liu Xuan
TI Autologous fat grafting combined with negative pressure wound therapy in
   severe diabetic foot ulcer: a case study
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE autologous fat graft; diabetes; diabetic foot ulcer; dressing;
   infection; negative pressure wound therapy; ulcer; wound
AB Objective: Hard-to-heal wounds are a surgical challenge, and diabetic foot ulcers (DFUs) are one of the most common and severe varieties. Previous studies have shown that autologous fat grafting (AFG) and negative pressure wound therapy (NPWT) have the potential to promote wound healing. This case study describes how these two methods together helped in the healing of a serious DFU.
   Case history: A 65-year-old female patient had a severe DFU on her right foot, with a 30-year history of disease and renal failure. By the time symptoms were evident, regular dressing changes and antibiotic treatment were inadequate. She received surgical debridement, AFG and NPWT. Finally, as the granulation tissue covered the full wound bed, the wound was closed by split-thickness skin grafting. One month later, the DFU was fully healed with no recurrences.
   Conclusion: The application of AFG or components of adipose tissue to treat hard-to-heal wounds has been researched at both the molecular level and in clinic. In this case, we have proved the curative effect of jointly using AFG and NPWT.
C1 [Zheng Biyao; Xu Gang; Jiang Hai; Duan Chenwang; Liu Xuan] Tangshan Gongren Hosp, Dept Burns & Plast Surg, Tangshan, Peoples R China.
   [Zheng Biyao] North China Univ Sci & Technol, Grad Sch, Tangshan, Peoples R China.
C3 North China University of Science & Technology
RP Xu, G (通讯作者)，Tangshan Gongren Hosp, Dept Burns & Plast Surg, Tangshan, Peoples R China.
EM xugang65@sina.com
CR Almeida JE, 2018, J WOUND CARE, V27, pS28, DOI 10.12968/jowc.2018.27.Sup2.S28
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NR 18
TC 5
Z9 6
U1 0
U2 6
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD APR
PY 2021
VL 30
SU 4
BP S38
EP S40
DI 10.12968/jowc.2021.30.Sup4.S38
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA RO6KY
UT WOS:000641153500006
PM 33856926
DA 2026-07-24
ER

PT J
AU Miyahara, HD
   Serzedello, FR
   Ejnisman, L
   Lima, ALLM
   Vicente, JRN
   Helito, CP
AF Miyahara, Helder de Souza
   Serzedello, Felipe Ribeiro
   Ejnisman, Leandro
   Lei Munhoz Lima, Ana Lucia
   Negreiros Vicente, Jost Ricardo
   Helito, Camilo Partezani
TI INCISIONAL NEGATIVE-PRESSURE WOUND THERAPY IN REVISION TOTAL HIP
   ARTHROPLASTY DUE TO INFECTION
SO ACTA ORTOPEDICA BRASILEIRA
LA English
DT Article
DE Negative-pressure wound therapy; Arthroplasty; replacement; hip;
   Surgical wound dehiscence
ID SURGICAL SITE COMPLICATIONS; KNEE ARTHROPLASTY; DRESSINGS; SURGERY;
   SYSTEM
AB Objective: To present our institution's experience with negative-pressure wound therapy (NPWT) as an adjuvant in wound healing of patients who have undergone revision total hip arthroplasty (THA) due to septic loosening in the presence of active fistula. Methods: We prospectively assessed patients presenting with THA infection, associated with the presence of fistula, treated with a PICO (R) device for NPWT, in combination with the standard treatment for prosthesis infection in our institution. Resolution of the infectious process and healing of the surgical wound without complications were considered an initial favorable outcome. Results: We assessed 10 patients who used PICO (R) in our department. No complications were identified in association with the use of the NPWT device. The mean follow-up of the patients after use of the device was 12.7 months. Only one patient progressed with fistula reactivation and recurrence of infection. Conclusion: NPWT can be used in wound complications and infection following THA procedures safely and with promising results. Randomized prospective studies should be conducted to confirm its effectiveness.
C1 [Miyahara, Helder de Souza; Serzedello, Felipe Ribeiro; Ejnisman, Leandro; Negreiros Vicente, Jost Ricardo] Univ Sao Paulo, Fac Med, Inst Ortopedia & Traumatol, Hosp Clin HCFMUSP,Hip Grp, Sao Paulo, SP, Brazil.
   [Lei Munhoz Lima, Ana Lucia] Univ Sao Paulo, Fac Med, Inst Ortopedia & Traumatol, Hosp Clin HCFMUSP,Hosp Infect Comm, Sao Paulo, SP, Brazil.
   [Helito, Camilo Partezani] Univ Sao Paulo, Fac Med, Inst Ortopedia & Traumatol, Hosp Clin HCFMUSP,Knee Grp, Sao Paulo, SP, Brazil.
   [Helito, Camilo Partezani] Hosp Sirio Libanes, Sao Paulo, Brazil.
   [Miyahara, Helder de Souza; Serzedello, Felipe Ribeiro; Ejnisman, Leandro; Lei Munhoz Lima, Ana Lucia; Negreiros Vicente, Jost Ricardo; Helito, Camilo Partezani] Univ Sao Paulo, Fac Med, Dept Orthoped & Traumatol, Lab Invest Med Sistema Musculoesquelet,Hip Surg D, Sao Paulo, SP, Brazil.
C3 Universidade de Sao Paulo; Universidade de Sao Paulo; Universidade de
   Sao Paulo; Hospital Sirio Libanes; Universidade de Sao Paulo
RP Miyahara, HD (通讯作者)，Rua Dr Ovidio Pires de Campos 333, BR-05403010 Sao Paulo, SP, Brazil.
EM helder_miyahara@hotmail.com
RI ; Partezani Helito, Camilo/X-3880-2019; Lima, Ana Lucia
   Munhoz/L-7898-2017; Ejnisman, Leano/HTP-2565-2023
OI Miyahara, Helder/0000-0002-2532-2685; Partezani Helito,
   Camilo/0000-0003-1139-2524; Lima, Ana Lucia Munhoz/0000-0002-2396-9880;
   Ejnisman, Leano/0000-0002-9866-1960
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NR 20
TC 6
Z9 8
U1 0
U2 3
PU ATHA COMUNICACAO & EDITORA
PI SAO PAULO SP
PA RUA MACHADO BITTENCOURT, 190-40 ANDAR, CONJ 410, SAO PAULO SP, 00000,
   BRAZIL
SN 1413-7852
EI 1809-4406
J9 ACTA ORTOP BRAS
JI Acta Ortop. Bras.
PD SEP-OCT
PY 2018
VL 26
IS 5
BP 300
EP 304
DI 10.1590/1413-785220182605196038
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA GY9QQ
UT WOS:000448984100004
PM 30464709
OA Green Published, Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kirsner, RS
   Zimnitsky, D
   Robinson, M
AF Kirsner, Robert S.
   Zimnitsky, Dmitry
   Robinson, Michael
TI A prospective, randomized, controlled clinical study on the
   effectiveness of a single-use negative pressure wound therapy system,
   compared to traditional negative pressure wound therapy in the treatment
   of diabetic ulcers of the lower extremities
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID EVIDENCE-BASED RECOMMENDATIONS; STEPS
AB A multicenter, phase 4, randomized, comparative-efficacy study in subjects with lower extremity wounds was carried out to compare wound closure rates, for a single-use negative pressure wound therapy (s-NPWT) versus traditional NPWT (t-NPWT) systems over a 12-week treatment period. From the initial population of patients with diabetic foot ulcers (DFU) and venous leg ulcers (VLU), we analyzed a subgroup of patients with diabetes mellitus and leg and foot ulcers (either DFUs or VLUs in diabetics), termed, the diabetic lower extremity ulcers (DLEU). In the DLEU group, there were 95 patients in intention-to-treat (ITT) and 61 patients in per protocol (PP) populations, respectively. We found a significant difference in favor of s-NPWT over t-NPWT in the confirmed wound closures at 12 weeks both in ITT (p < 0.001) and PP populations (p = 0.017). Significantly higher wound closure rates in s-NPWT group suggest that s-NPWT should be preferred NPWT option for DLEU.
C1 [Kirsner, Robert S.] Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA.
   [Zimnitsky, Dmitry] Smith Nephew, Global Clin Strategy, Cary, NC USA.
   [Robinson, Michael] Smith Nephew, Global Data Analyt, Kingston Upon Hull, N Humberside, England.
C3 University of Miami; Smith & Nephew
RP Kirsner, RS (通讯作者)，Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA.
EM rkirsner@med.miami.edu
FU Smith+Nephew
FX This study was sponsored by Smith+Nephew.
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NR 15
TC 9
Z9 13
U1 2
U2 8
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD NOV
PY 2021
VL 29
IS 6
BP 908
EP 911
DI 10.1111/wrr.12966
EA SEP 2021
PG 4
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA WS3HE
UT WOS:000696012300001
PM 34525239
DA 2026-07-24
ER

PT J
AU Deluca, J
   Gatscher, B
   Tappeiner, L
   Pichler, M
   Eisendle, K
AF Deluca, J.
   Gatscher, B.
   Tappeiner, L.
   Pichler, M.
   Eisendle, K.
TI Direct comparison between negative wound pressure therapy and negatively
   charged polystyrene microspheres in wound bed preparation for split skin
   grafting in two large symmetric whole circumference leg ulcers, a single
   patient experience
SO JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
LA English
DT Letter
ID VACUUM-ASSISTED CLOSURE; DEVICE
C1 [Deluca, J.; Gatscher, B.; Tappeiner, L.; Pichler, M.; Eisendle, K.] Med Univ Innsbruck, Cent Teaching Hosp Bolzano, Acad Teaching Dept, Dept Dermatol Venerol & Allergol, Bolzano, Italy.
C3 Krankenhaus Bozen
RP Eisendle, K (通讯作者)，Med Univ Innsbruck, Cent Teaching Hosp Bolzano, Acad Teaching Dept, Dept Dermatol Venerol & Allergol, Bolzano, Italy.
EM Klaus.eisendle@asbz.it
RI Eisendle, Klaus/H-6798-2019
OI Eisendle, Klaus/0000-0002-8234-9964
CR Barendse-Hofmann M G, 2009, J Wound Care, V18, P79
   DeFranzo AJ, 1999, PLAST RECONSTR SURG, V104, P2145, DOI 10.1097/00006534-199912000-00031
   Guest JF, 2015, INT WOUND J, V12, P70, DOI 10.1111/iwj.12055
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NR 10
TC 6
Z9 7
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0926-9959
EI 1468-3083
J9 J EUR ACAD DERMATOL
JI J. Eur. Acad. Dermatol. Venereol.
PD AUG
PY 2015
VL 29
IS 8
BP 1649
EP 1651
DI 10.1111/jdv.12527
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA CM9FM
UT WOS:000358012800031
PM 24754454
DA 2026-07-24
ER

PT J
AU Matiasek, J
   Djedovic, G
   Mattesich, M
   Morandi, E
   Pauzenberger, R
   Pikula, R
   Verstappen, R
   Pierer, G
   Koller, R
   Rieger, UM
AF Matiasek, J.
   Djedovic, G.
   Mattesich, M.
   Morandi, E.
   Pauzenberger, R.
   Pikula, R.
   Verstappen, R.
   Pierer, G.
   Koller, R.
   Rieger, U. M.
TI The combined use of NPWT and instillation using an octenidine based
   wound rinsing solution: a case study
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE negative pressure wound therapy with instillation; octenilin wound
   irrigation solution; pressure ulcer; wound bed preparation, flap
   closure; negative pressure wound therapy
ID RESISTANT STAPHYLOCOCCUS-AUREUS; METHICILLIN-RESISTANT; THERAPY;
   DIHYDROCHLORIDE; FLAP
AB Effective wound bed preparation is an essential element in the healing of chronic wounds, including pressure ulcers (PUs). Negative pressure wound therapy (NPWT) reduces oedema, stimulates the formation of granulation tissue and helps remove wound exudate. This helps prepare the wound bed for secondary healing, skin grafting or coverage with flaps. Combining NPWT with an instillation phase using an antiseptic (octenidine based) irrigation solution is a novel approach to PU management.
   Three patients with Category 4 gluteal PUs were treated with NPWT and instillation fluid, following surgical debridement of necrotic tissue. The aim was to achieve optimal wound bed preparation prior to wound closure by local fasciocutaneous flap.
   The antiseptic efficacy of octenilin wound irrigation solution in microorganism eradication was quantified by in vitro tests simulating real conditions using leg ulcer vacuum exudates.
   All wounds completely healed after four weeks, and no adverse incidents occurred due to instillation of octenidine. No recurrence of the PU occurred during a one year follow-up.
C1 [Matiasek, J.; Koller, R.] Wilhelminenspital Stadt Wien, Dept Plast Aesthet & Reconstruct Surg, Vienna, Austria.
   [Matiasek, J.; Djedovic, G.; Mattesich, M.; Morandi, E.; Pauzenberger, R.; Pikula, R.; Verstappen, R.; Pierer, G.; Rieger, U. M.] Med Univ Innsbruck, Dept Plast Reconstruct & Aesthet Surg, A-6020 Innsbruck, Austria.
   [Rieger, U. M.] St Markus Hosp, Dept Plast & Aesthet Surg Reconstruct & Hand Surg, Frankfurt, Germany.
C3 Wilhelminenspital; Medical University of Innsbruck
RP Matiasek, J (通讯作者)，Wilhelminenspital Stadt Wien, Dept Plast Aesthet & Reconstruct Surg, Vienna, Austria.
OI Verstappen, Ralph/0000-0002-2609-109X; Pauzenberger,
   Reinhard/0000-0001-7146-6260
CR Ahluwalia R, 2009, INT WOUND J, V6, P355, DOI 10.1111/j.1742-481X.2009.00624.x
   [Anonymous], TREATM PRESS ULC QUI
   [Anonymous], 2009, BACT CHALL TIM REACT
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   Broder K., 2010, WOUNDS, V22, pE13
   Cosgrove SE, 2003, CLIN INFECT DIS, V36, P53, DOI 10.1086/345476
   Desai KK, 2012, CLIN PLAST SURG, V39, P311, DOI 10.1016/j.cps.2012.05.002
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   Giuglea Carmen, 2010, J Med Life, V3, P149
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   Hübner NO, 2010, SKIN PHARMACOL PHYS, V23, P244, DOI 10.1159/000314699
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   Kim T, 2001, INFECT CONT HOSP EP, V22, P99, DOI 10.1086/501871
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   Vogt PeterM., 2011, Praxis der Plastischen Chirurgie
NR 28
TC 16
Z9 24
U1 0
U2 5
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD NOV
PY 2014
VL 23
IS 11
BP 590
EP 596
DI 10.12968/jowc.2014.23.11.590
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA AS8BK
UT WOS:000344475200009
PM 25375407
DA 2026-07-24
ER

PT J
AU Morimoto, N
   Kuro, A
   Yamauchi, T
   Horiuchi, A
   Kakudo, N
   Sakamoto, M
   Suzuki, K
   Kusumoto, K
AF Morimoto, Naoki
   Kuro, Atsuyuki
   Yamauchi, Takashi
   Horiuchi, Ai
   Kakudo, Natsuko
   Sakamoto, Michiharu
   Suzuki, Kenji
   Kusumoto, Kenji
TI Combined use of fenestrated-type artificial dermis and topical negative
   pressure wound therapy for the venous leg ulcer of a rheumatoid
   arthritis patient
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Fenestrated-type artificial dermis; Grip tape technique; Negative
   pressure wound therapy; Venous leg ulcer
AB We report a case of circumferential venous leg ulcer in a rheumatoid arthritis patient. Mesh skin grafting was performed in another hospital, but the graft failed and the patient was referred to our hospital. This ulcer was treated by the combination therapy of a fenestrated-type artificial dermis with negative pressure wound therapy (NPWT) and secondary mesh grafting using our 'grip tape technique'. NPWT was started at -100 mmHg and continued until the formation of dermis-like tissue. A section stained using haematoxylin and eosin and an anti-alpha SMA (alpha smooth muscle actin) immunohistological section of the biopsy from dermis-like tissue showed an abundant infiltration of fibroblasts and capillary formation beneath the fenestration of the silicone sheet. Threefold mesh skin grafting was subsequently performed and it was taken up completely. The fenestrated-type artificial dermis in combination with NPWT produced good results without infection in the treatment of complex wounds. In addition, our 'grip tape technique' was useful to apply polyurethane foam to the entire surface of the lower leg.
C1 [Morimoto, Naoki; Kuro, Atsuyuki; Yamauchi, Takashi; Horiuchi, Ai; Kakudo, Natsuko; Kusumoto, Kenji] Kansai Med Univ, Dept Plast & Reconstruct Surg, Hirakata, Osaka 5731010, Japan.
   [Sakamoto, Michiharu] Kyoto Univ, Dept Plast & Reconstruct Surg, Grad Sch Med, Kyoto, Japan.
   [Suzuki, Kenji] Kansai Med Univ, Takii Hosp, Dept Plast & Reconstruct Surg, Moriguchi, Osaka 570, Japan.
C3 Kansai Medical University; Kyoto University; Kansai Medical University
RP Morimoto, N (通讯作者)，Kansai Med Univ, Dept Plast & Reconstruct Surg, 2-5-1 Shin Machi, Hirakata, Osaka 5731010, Japan.
EM morimotn@hirakata.kmu.ac.jp
OI Kakudo, Natsuko/0000-0001-9785-1490; Morimoto, Naoki/0000-0002-0712-3172
CR Baldwin C, 2009, ANN PLAS SURG, V62, P92, DOI 10.1097/SAP.0b013e31817762fd
   Fraccalvieri M, 2012, INT WOUND J, V9, P214, DOI 10.1111/j.1742-481X.2011.00878.x
   Hayn E, 2014, INT WOUND J, V11, P675, DOI 10.1111/iwj.12028
   Kuro A, 2014, J PLAST RECONSTR AES
   Moiemen NS, 2010, BURNS, V36, P764, DOI 10.1016/j.burns.2010.04.011
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Morimoto N, 2014, INT WOUND J, V11, P183, DOI 10.1111/j.1742-481X.2012.01064.x
   Morimoto N, 2013, TISSUE ENG PT A, V19, P1931, DOI [10.1089/ten.tea.2012.0634, 10.1089/ten.TEA.2012.0634]
   Potter MJ, 2008, BURNS, V34, P164, DOI 10.1016/j.burns.2007.06.020
   Suzuki S, 2000, BRIT J PLAST SURG, V53, P659, DOI 10.1054/bjps.2000.3426
   Yannas IV, 2011, PLAST RECONSTR SURG, V127, p60S, DOI 10.1097/PRS.0b013e318200a44d
NR 11
TC 4
Z9 7
U1 0
U2 13
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD FEB
PY 2016
VL 13
IS 1
BP 137
EP 140
DI 10.1111/iwj.12422
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA DA9QH
UT WOS:000368144100024
PM 25650053
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Mendonca, DA
   Cosker, T
   Makwana, NK
AF Mendonca, DA
   Cosker, T
   Makwana, NK
TI Vacuum-assisted closure to aid wound healing in foot and ankle surgery
SO FOOT & ANKLE INTERNATIONAL
LA English
DT Article
DE diabetic ulcers; vacuum-assisted closure; wound closure
ID DEGLOVING INJURIES; RANDOMIZED-TRIAL; EXPERIENCE; MANAGEMENT; THERAPY;
   DEVICE; ULCERS
AB Background. Although vacuum-assisted closure (VAC) is a well-established technique in other surgical specialties, its use has not been established in the foot and ankle. The aims of this study were to determine if vacuum-assisted closure therapy (VAC) helps assist closure in diabetic foot ulcers and wounds secondary to peripheral vascular disease, if it helps debride wounds, and if it prevents the need for further surgery. Methods: We retrospectively reviewed 15 patients (18 wounds or ulcers) with primary diagnoses of diabetes (10 patients), chronic osteomyelitis (two patients), peripheral vascular disease (two patients), and spina bifida (one patient). Eleven of the 15 patients had serious comorbidities, such as peripheral neuropathy, renal failure, and wound dehiscence. All wounds were surgically debrided before VAC therapy was applied according to the manufacturer's instructions. The main outcome measures were time to satisfactory wound closure, changes in the wound surface area, and the need for further surgery. Results: Satisfactory healing was achieved in 13 of the 18 wounds or ulcers at an average of 2.5 months. VAC therapy failed in five patients (five class III ulcers), three of whom required below-knee amputations. Wound or ulcer size decreased from an average of 7.41 cm(2) before treatment to an average of 1.58 cm(2) after treatment. Conclusion: VAC therapy is a useful adjunct to the standard treatment of chronic wound or ulcers in patients with diabetes or peripheral vascular disease. Its use in foot and ankle surgery leads to a quicker wound closure and, in most patients, avoids the need for further surgery.
C1 Wrexham Maelor Hosp, Dept Orthopaed & Trauma, Wrexham, Wales.
RP Mendonca, DA (通讯作者)，10 St Davids Court,Holt Rd, Wrexham LL13 9AN, Wales.
EM derickmen@yahoo.com
OI Mendonca, Derek Amith/0000-0002-7861-1966
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 20
TC 29
Z9 34
U1 0
U2 3
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1071-1007
EI 1944-7876
J9 FOOT ANKLE INT
JI Foot Ankle Int.
PD SEP
PY 2005
VL 26
IS 9
BP 761
EP 766
DI 10.1177/107110070502600915
PG 6
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 963DH
UT WOS:000231783000016
PM 16174508
DA 2026-07-24
ER

PT J
AU Misky, A
   Hotouras, A
   Ribas, Y
   Ramar, S
   Bhan, C
AF Misky, A.
   Hotouras, A.
   Ribas, Y.
   Ramar, S.
   Bhan, C.
TI A systematic literature review on the use of vacuum assisted closure for
   enterocutaneous fistula
SO COLORECTAL DISEASE
LA English
DT Review
DE Enterocutaneous fistula; vacuum assisted closure; negative pressure
   therapy
ID GASTROINTESTINAL FISTULAS; OPEN ABDOMEN; MANAGEMENT; MORTALITY
AB AimEnterocutaneous fistula (ECF) is considered to be one of the most challenging complications a general surgeon can encounter. The current mainstay of treatment is surgical closure, associated with significant morbidity and mortality. Vacuum assisted closure (VAC) has been successfully used for closure of persistent abdominal wounds for a number of years. This study aims to investigate whether current literature supports the use of VAC for ECF.
   MethodA PubMed search of the search terms enterocutaneous fistula' and vacuum assisted closure/therapy' was performed in December 2014. Results were restricted to articles involving human subjects with an available abstract and full text written between 1950 and 2014. The end-points analysed included rate of fistula closure, duration of follow-up, and morbidity and mortality where available.
   ResultsTen studies (all level IV) including 151 patients were examined. In all except one, surgery was the underlying aetiology with median number of fistulae per patient of one. The median rate of closure with VAC was 64.6% (7.7-100%) with healing occurring within 58 (12-90)days. Follow-up was only mentioned in three of the 10 studies, in which the patients were followed for 3, 20 and 28.5months. No complications were reported in all but one of the studies, in which abdominal wall disruption and intestinal obstruction were identified in a minority of patients.
   ConclusionThe included studies suggest that VAC therapy may be considered a safe treatment for ECF. The current evidence is generally of low level and characterized by heterogeneity. Definitive recommendations based on this information cannot therefore be made. Further studies are necessary to establish any proven benefit over standard surgical or conservative therapy.
C1 [Misky, A.] UCL, Sch Med, London, England.
   [Hotouras, A.] Univ Coll London Hosp, North East London Deanery, London, England.
   [Ribas, Y.] Consorci Sanitari Terrassa, Dept Surg, Barcelona, Spain.
   [Ramar, S.] Kings Coll Hosp London, London, England.
   [Bhan, C.] UCL, Dept Colorectal Surg, Whittington Hlth NHS Trust, London, England.
C3 University of London; University College London; UCL Medical School;
   University College London Hospitals NHS Foundation Trust; University of
   London; University College London; King's College Hospital NHS
   Foundation Trust; King's College Hospital; University of London;
   University College London
RP Hotouras, A (通讯作者)，Barts & London Queen Marys Sch Med & Dent, Natl Ctr Bowel Res & Surg Innovat, Barts Hlth NHS Trust, Acad Surg Unit, 1st Floor,Abernethy Bldg,2 Newark St, London E1 2AT, England.
EM alex007@doctors.org.uk
RI RIBAS, YOLANDA/AAG-1532-2020
OI RIBAS, YOLANDA/0000-0002-9254-2864; Misky, Adam/0000-0002-5679-6293
CR Alvarez AA, 2001, GYNECOL ONCOL, V80, P413, DOI 10.1006/gyno.2000.6092
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   [Anonymous], NEG PRESS WOUND THER
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NR 29
TC 21
Z9 31
U1 0
U2 7
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1462-8910
EI 1463-1318
J9 COLORECTAL DIS
JI Colorectal Dis.
PD SEP
PY 2016
VL 18
IS 9
BP 846
EP 851
DI 10.1111/codi.13351
PG 6
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA DW4QP
UT WOS:000383628400009
PM 27088556
DA 2026-07-24
ER

PT J
AU Mintziras, I
   Miligkos, M
   Bartsch, DK
AF Mintziras, Ioannis
   Miligkos, Michael
   Bartsch, Detlef Klaus
TI High risk of fistula formation in vacuum-assisted closure therapy in
   patients with open abdomen due to secondary peritonitis-a retrospective
   analysis
SO LANGENBECKS ARCHIVES OF SURGERY
LA English
DT Article
DE Vacuum-assisted closure therapy; Peritonitis; Open abdomen;
   Enterocutaneous fistula
ID TEMPORARY ABDOMINAL CLOSURE; PRESSURE WOUND THERAPY; FASCIAL CLOSURE;
   NONTRAUMA PATIENTS; SEPTIC PATIENTS; MANAGEMENT
AB The aim of this study was to evaluate the efficacy of vacuum-assisted closure therapy in patients with open abdomen due to secondary peritonitis and to identify possible risk factors of fistula formation.
   The hospital OPS-database (time period 2005-2014) was searched to identify patients treated with an open abdomen due to secondary peritonitis, who underwent vacuum-assisted closure therapy. Medical records were retrospectively analyzed for patients' characteristics, cause of peritonitis, duration of vacuum therapy, number of relaparotomies, fascial closure rates, and risk factors of fistula formation.
   Forty-three patients (19 male, 24 female) with a median age of 65 years (range 24-90 years) were identified. The major cause of secondary peritonitis was anastomotic leakage after intestinal anastomosis or bowel perforation, the median APACHE II score was 11. Median duration of VAC treatment was 12 days (range 3-88 days). Twenty of 43 (47 %) patients died from septic complications. Delayed fascial closure was obtained by suturing in 20 of 43 patients (47 %). Overall 16 of 43 (37 %) patients developed enteroatmospheric fistulas. Re-explorations after starting VAC treatment and duration of VAC therapy were significantly associated with the occurrence of enteroatmospheric fistulas (p < 0.001). ROC curve analysis determined the optimal duration of VAC therapy to reduce the risk of fistula formation at 13 days.
   Long-term VAC treatment of patients with an open abdomen due to secondary peritonitis results in a relatively low fascial closure rate and a high risk of fistula formation.
C1 [Mintziras, Ioannis; Bartsch, Detlef Klaus] Univ Marburg, Dept Visceral Thorac & Vasc Surg, Baldingerstr, D-35043 Marburg, Germany.
   [Miligkos, Michael] Univ Thessaly, Sch Med, Lab Biomath, Larisa, Greece.
C3 Philipps University Marburg; University of Thessaly
RP Mintziras, I (通讯作者)，Univ Marburg, Dept Visceral Thorac & Vasc Surg, Baldingerstr, D-35043 Marburg, Germany.
EM ioannis.mintziras@uk-gm.de
OI Miligkos, Michael/0000-0001-8021-2780
CR Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
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NR 22
TC 22
Z9 33
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1435-2443
EI 1435-2451
J9 LANGENBECK ARCH SURG
JI Langenbecks Arch. Surg.
PD AUG
PY 2016
VL 401
IS 5
BP 619
EP 625
DI 10.1007/s00423-016-1443-y
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DR1XP
UT WOS:000379698500005
PM 27150438
DA 2026-07-24
ER

PT J
AU Zhou, ZY
   Liu, YK
   Chen, HL
   Liu, F
AF Zhou, Zhen-Yu
   Liu, Ya-Ke
   Chen, Hong-Lin
   Liu, Fan
TI Wound management with vacuum assisted closure in surgical site infection
   after ankle surgery
SO INTERNATIONAL JOURNAL OF SURGERY
LA English
DT Article
DE Ankle surgery; Surgical site infection; Vacuum assisted closure;
   Standard moist wound care
ID TOPICAL NEGATIVE-PRESSURE; RANDOMIZED CONTROLLED-TRIAL; THERAPY; FOOT;
   MULTICENTER
AB Objective: The aim of this study was to compare the efficacy of vacuum assisted closure (VAC) with standard moist wound care (SMWC) in surgical site infection after ankle surgery.
   Methods: A prospective cohort was performed among patients with surgical site infection after ankle surgery between 2012 and 2013. The follow-up period was three month, and the efficacy end point was complete wound closure rate.
   Results: Ninety-four patients were analyzed, with 61 patients in the VAC group and 33 in the SMWC group. The complete wound closure rate in the VAC group was higher than that in the SMWC group at 3 month follow up (90.2% Vs. 72.7%, p = 0.028). The median time to complete wound closure was 31 days (95% CI 20.2-41.8) for VAC, and 63 days (95% CI 46.9-79.1) for SMWC (chi(2) = 4.023, p = 0.045). In the superficial infection subgroup, the median times to complete wound closure were 20 days (95% CI 14.2-35.1) in the VAC group and 42 days (95% CI 35.4-69.4) in SMWC group (chi(2) = 4.331, p = 0.041). In the deep subgroup, the median times to complete wound closure were 46 days (95% CI 28.2-65.9) in the VAC group and 75 days (95% CI 43.2-79.6) in SMWC group (chi(2) = 6.475, p = 0.026).
   Conclusion: Our result showed that vacuum assisted closure was more effective than standard moist wound care in surgical site infection after ankle surgery. (C) 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.
C1 [Zhou, Zhen-Yu; Liu, Ya-Ke; Liu, Fan] Nantong Univ, Affiliated Hosp, Dept Orthopaed, Nantong, Jiangsu, Peoples R China.
   [Chen, Hong-Lin] Nantong Univ, Nantong City 226001, Jiangsu, Peoples R China.
C3 Nantong University; Nantong University
RP Liu, F (通讯作者)，Nantong Univ, Affiliated Hosp, Dept Orthopaed, Xisi Rd 20, Nantong City 226001, Jiangsu, Peoples R China.
EM pphss@126.com
RI Chen, Hong-Lin/E-5418-2010
OI Liu, Fan/0000-0002-4967-7595
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NR 16
TC 4
Z9 6
U1 0
U2 5
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1743-9191
EI 1743-9159
J9 INT J SURG
JI Int. J. Surg.
PD MAY
PY 2015
VL 17
BP 15
EP 18
DI 10.1016/j.ijsu.2015.03.008
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CH4EQ
UT WOS:000353986200004
PM 25791994
DA 2026-07-24
ER

PT J
AU Ditterich, D
   Rexer, M
   Rupprecht, H
AF Ditterich, D
   Rexer, M
   Rupprecht, H
TI Vacuum assisted closure in the treatment of pleural empyema first
   experiences with intrathoracal application
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nuernberg, GERMANY
DE vacuum-assisted closure; thoracic surgery; pleural empyema
ID STERNAL WOUND INFECTIONS; DEFINITIVE CLOSURE; THERAPY; SURGERY
AB Meanwhile vacuum-assisted closure (V.A.C.(R)) therapy belongs to the standard procedures in cardiovascular surgery. Its intrathoracal application is mentioned in one unique case-report in literature. We like to show our first experiences with this technique demonstrating three cases with pleural infection. One patient with bronchial stump insufficiency, one with pleural empyema and one with penetrating abscess of the chest was treated with V.A.C.(R)-therapy. We applied a combination of microporous silicon fleece and polyurethan foam in direct neighbourhood to ventilated lung areas inside the thoracic cavity. One patient died of metastasis of his cancer disease, while wound situation and bronchial stump insufficiency could be treated well. Two patients could be treated successfully and be discharged out of the hospital. No complications due to V.A.C.(R)-therapy could be seen, such as fistulas of the lung or bleeding of the mediastinal organs. Intrathoracal VA-C.(R)-therapy can be performed as a good therapeutic option in the treatment of septic diseases inside the chest.
C1 Chirurg Klin 1, D-90766 Furth, Germany.
RP Ditterich, D (通讯作者)，Chirurg Klin 1, Jakob Henle Str 1, D-90766 Furth, Germany.
EM dditterich@aol.com
CR Clubley Lisa, 2005, Nurs Times, V101, P44
   Ditterich D, 2004, ZBL CHIR, V129, pS137
   Fleck T, 2004, ZBL CHIR, V129, pS35, DOI 10.1055/s-2004-822615
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NR 12
TC 14
Z9 16
U1 0
U2 1
PU JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
PI STUTTGART
PA RUEDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S133
EP S138
DI 10.1055/s-2006-921499
PG 6
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 034DB
UT WOS:000236904100031
PM 16575664
DA 2026-07-24
ER

PT J
AU Sutton, L
   Edwards, D
   McColl, M
AF Sutton, L.
   Edwards, D.
   McColl, M.
TI Outpatient negative pressure dressing therapy for pretibial lacerations
   in a patient with high anaesthetic risk: a case study
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE adult congenital cardiac disease; negative pressure wound therapy;
   pretibial laceration; pulmonary atresia
ID CONGENITAL HEART-DISEASE; MANAGEMENT; ADULTS
AB Pretibial lacerations are a common cause of presentation to accident and emergency departments. The management of these wounds is contentious with a variation in practise between individual institutions. We present the case of a 49-year-old female with a background of pulmonary atresia and associated pulmonary hypertension, who underwent successful outpatient negative pressure wound therapy (NPWT) for three pretibial lacerations. We would propose that this therapy is an effective option for the management of these wounds in independently mobile patients who are at high-risk when under anaesthetic.
C1 [Sutton, L.] Univ Coll London Hosp NHS Trust, Head & Neck Ctr, London, England.
   [Sutton, L.] UCL, UCL Canc Inst, London, England.
   [Edwards, D.] Royal London Hosp, Barts Hlth NHS Trust, Plast Surg Dept, London, England.
C3 University College London Hospitals NHS Foundation Trust; University of
   London; University College London; University of London; University
   College London; Barts Health NHS Trust; Royal London Hospital
RP Sutton, L (通讯作者)，Univ Coll London Hosp NHS Trust, Head & Neck Ctr, London, England.; Sutton, L (通讯作者)，UCL, UCL Canc Inst, London, England.
EM liammsutton@gmail.com
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NR 15
TC 0
Z9 0
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD DEC
PY 2017
VL 26
IS 12
BP 762
EP 764
DI 10.12968/jowc.2017.26.12.762
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA FQ2LG
UT WOS:000418187400009
PM 29244964
DA 2026-07-24
ER

PT J
AU Guan, XF
   Zhu, GY
   Jiang, HW
   Wang, B
   Cheng, JX
AF Guan, Xiaofang
   Zhu, Guangyong
   Jiang, Haowei
   Wang, Bo
   Cheng, Jiaxin
TI Comparative efficacy of advanced therapeutic modalities for diabetic
   foot ulcers: a systematic review and meta-analysis including NPWT, stem
   cells, ESWT, and bioengineered treatments
SO FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
LA English
DT Review
DE DFU; diabetic foot ulcers; exosomes; extracorporeal shockwave therapy;
   mesenchymal stem cells; MSc; negative pressure wound therapy; Npwt
ID PRESSURE WOUND THERAPY; VACUUM-ASSISTED CLOSURE; PLATELET-RICH PLASMA;
   CONTROLLED-TRIAL; MULTICENTER; MANAGEMENT
AB Background Diabetic foot ulcers (DFUs) are highly debilitating and often necessitate cutting-edge treatments apart from the usual care. This systematic review and meta-analysis have compared the efficacy of Negative Pressure Wound Therapy (NPWT)/VAC, cell-based therapies (MSC-based therapies), artificial skin, extracorporeal shockwave therapy (ESWT), and platelet-rich plasma (PRP) interventions in promoting healing of difficult wounds, as well as healing by other means. Methods The extensive search identified 49 randomized controlled trials. For data analysis, a random-effects model with inverse-variance weighting was used to obtain standardized mean differences (SMDs) with 95% confidence intervals (CIs). The presence of publication bias was determined using funnel plots and Egger's test, while the quality of the studies was assessed by means of Jadad scores and risk of bias tools. GRADE was employed to assess the certainty of the evidence. Results Sub-group analysis revealed that NPWT significantly accelerated wound closure compared to standard care SMD of -0.39 (95% CI: 0.57 to -0.21; I2 = 49%), indicating faster healing times, used days to measure time showed an SMD of -0.94 (95% CI: 1.07 to -0.80; I2 = 0%) which showed that patients healed at a faster rate. The comparison of different devices and techniques showed an SMD of 0.98 (95% CI: 0.75-1.21; I2 = 0%), indicating that additional treatments resulted in a greater reduction in wound area. The results were statistically significant because all p-values were lower than 0.05. MSC-based therapies showed similar overall healing (SMD = 0.46, 95% CI: 0.24-0.69) and faster closure (SMD = -1.04, 95% CI: 1.28 to -0.8). Additionally, trials of bioengineered skin substitutes, ESWT, and PRP all showed statistically significant improvements in time to wound closure and overall healing. Relative to the control group, adverse events were fewer in the NPWT and PRP groups (SMD = -0.24, 95% CI: 0.42 to -0.05). Conclusion The NPWT and MSC-based therapy, in particular, represent major improvements in healing outcomes for diabetic foot ulcers (DFUs) and in the speed of closure compared with standard treatment.
C1 [Guan, Xiaofang; Jiang, Haowei; Wang, Bo; Cheng, Jiaxin] First Peoples Hosp Xiaoshan Dist, Hand & Foot Surg, Hangzhou, Peoples R China.
   [Zhu, Guangyong] Hangzhou Hosp Zhejiang Med Hlth Grp, Dept Orthoped, Hangzhou, Peoples R China.
RP Cheng, JX (通讯作者)，First Peoples Hosp Xiaoshan Dist, Hand & Foot Surg, Hangzhou, Peoples R China.
EM chengjx_ok@126.com
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   Zelen CM, 2016, INT WOUND J, V13, P272, DOI 10.1111/iwj.12566
   Zelen CM, 2015, INT WOUND J, V12, P724, DOI 10.1111/iwj.12395
   Zhang L, 2018, INT WOUND J, V15, P590, DOI 10.1111/iwj.12902
   Zhong MF, 2024, INT WOUND J, V21, DOI [10.1111/iwj.70089, 10.1111/iwj.70089]
   Zollino I., 2017, RECALCITRANT CHRONIC
NR 54
TC 0
Z9 0
U1 2
U2 2
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-4185
J9 FRONT BIOENG BIOTECH
JI Front. Bioeng. Biotechnol.
PD APR 29
PY 2026
VL 14
AR 1792670
DI 10.3389/fbioe.2026.1792670
EA APR 2026
PG 22
WC Biotechnology & Applied Microbiology; Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biotechnology & Applied Microbiology; Engineering
GA HW7FT
UT WOS:001764498500001
PM 42137620
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Aydin, U
   Ozgenel, Y
   Kanturk, R
AF Aydin, Ufuk
   Ozgenel, Yesim
   Kanturk, Riza
TI Vacuum-assisted closure therapy in newborn gangrene
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article
DE Newborn; Gangrene; Vacuum-Assisted Closure Therapy
AB Gangrene of the newborn or neonatal gangrene is very uncommon, and it usually involves the extremities. Neonatal gangrene seems to be more frequent in pregnancies re-leated with spontaneus rupture of the amniotic sac leading to delayed delivery or dry labour. However, in most of the cases, no aetiological factor can be found. Foetal pressure necrosis and amniotic band sequence are two of the most common causes of this condition. Thrombosis, emboli, congenital heart disease, coagulopathy, sepsis and polycythaemia are some of the other aetiologic factors. Treatment of this condition is usually conservative and supportive. Conservative treatment includes adequate hydration, prevention from infections and allowing the involved area to demarcate in an aseptic environment. In some cases, surgical debridement and further reconstruction can be necessary. In order to prepare the wound bed for surgical closure after surgical debridement, vacuum-assisted closure (VAC) therapy can be a new, highly effective method in the treatment of newborn gangrene. In this article, a case of a neonatal gangrene treated with the application of VAC therapy is presented. (C) 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Aydin, Ufuk; Ozgenel, Yesim; Kanturk, Riza] Uludag Univ, Dept Plast & Reconstruct & Aesthet Surg, TR-16059 Bursa, Turkey.
C3 Uludag University
RP Aydin, U (通讯作者)，Uludag Univ, Dept Plast & Reconstruct & Aesthet Surg, Gorukle Campus, TR-16059 Bursa, Turkey.
EM drufukaydin@gmail.com
CR Bütter A, 2006, J PEDIATR SURG, V41, P940, DOI 10.1016/j.jpedsurg.2006.01.061
   HENSINGER RN, 1975, J BONE JOINT SURG AM, VA 57, P121, DOI 10.2106/00004623-197557010-00025
   MARJORIEARCA J, 2005, PEDIAT SURG INT, V21, P532
   Özgenel GY, 2000, EUR J PLAST SURG, V23, P429, DOI 10.1007/s002380000194
   Ramnarine IR, 2002, EUR J CARDIO-THORAC, V22, P1029, DOI 10.1016/S1010-7940(02)00562-6
NR 5
TC 6
Z9 7
U1 0
U2 2
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD MAR
PY 2010
VL 63
IS 3
BP E277
EP E279
DI 10.1016/j.bjps.2009.05.049
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 551JA
UT WOS:000274202700046
PM 19581134
DA 2026-07-24
ER

PT J
AU Jaehn, T
   Sievers, R
   Junger, A
   Graunke, F
   Blings, A
   Reichert, B
AF Jaehn, T.
   Sievers, R.
   Junger, A.
   Graunke, F.
   Blings, A.
   Reichert, B.
TI Fatal hyperpyrexia in an adolescent patient with severe burns after a
   traffic accident
SO UNFALLCHIRURG
LA German
DT Article
DE Burns; Dermis replacement; Hyperpyrexia; Negative pressure wound
   therapy; Propofol infusion syndrome
ID HYPERTHERMIA
AB After a motorcycle accident a 16-year-old patient suffered severe burns to 40.5 % of the total body surface area (TBSA) of which 37 % were deep subdermal burns. After tangential and partly epifascial necrosectomy, Integra. was used as a temporary dermis replacement material for the lower extremities, combined with extensive negative pressure wound therapy (NPWT). In the further course of the treatment the patient developed uncontrollable hyperpyrexia with a fatal outcome. Possible influencing factors, such as the dermis replacement material combined with NPWT over large areas as well as the differential diagnoses propofol infusion syndrome, heatstroke and malignant hyperthermia are discussed.
C1 [Jaehn, T.; Sievers, R.; Graunke, F.; Reichert, B.] Paracelsus Med Privatuniv, Klinikum Nurnberg, Zentrum Schwerbrandverletzte, Univ Klin Plast Wiederherstellende & Handchirurg, Nurnberg, Germany.
   [Junger, A.; Blings, A.] Paracelsus Med Privatuniv, Klinikum Nurnberg, Univ Klin Anasthesiol & Operat Intens Med, Nurnberg, Germany.
C3 Klinikum Nurnberg; Klinikum Nurnberg
RP Jaehn, T (通讯作者)，Paracelsus Med Privatuniv, Klinikum Nurnberg, Zentrum Schwerbrandverletzte, Univ Klin Plast Wiederherstellende & Handchirurg, Nurnberg, Germany.
EM tobias.jaehn@klinikum-nuernberg.de
CR Adam H, 2007, ANASTH INTENSIVMED, V10, P692
   Bouchama A, 2002, NEW ENGL J MED, V346, P1978, DOI 10.1056/NEJMra011089
   BROCHHAUSEN C, 2008, INTENSIVMED NOTFALLM, V45, P31, DOI DOI 10.1007/s00390-007-0836-0
   Diedrich Daniel A, 2011, J Intensive Care Med, V26, P59, DOI 10.1177/0885066610384195
   Dunker M, 2001, ANAESTHESIST, V50, P500, DOI 10.1007/s001010100169
   Hüttemann K, 2009, FORTSCHR NEUROL PSYC, V77, P203, DOI 10.1055/s-0028-1109297
   Jurkat-Rott K, 2000, MUSCLE NERVE, V23, P4, DOI 10.1002/(SICI)1097-4598(200001)23:1<4::AID-MUS3>3.0.CO;2-D
   Rosenberg H, 2007, ORPHANET J RARE DIS, V2, DOI 10.1186/1750-1172-2-21
   Schutte JK, 2006, ANASTH INTENSIVMED, V7-8, P454
   Wappler F, 2001, EUR J ANAESTH, V18, P632, DOI 10.1046/j.1365-2346.2001.00888.x
NR 10
TC 0
Z9 1
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0177-5537
EI 1433-044X
J9 UNFALLCHIRURG
JI Unfallchirurg
PD JUL
PY 2016
VL 119
IS 7
BP 609
EP 612
DI 10.1007/s00113-015-0132-6
PG 4
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA DX9TZ
UT WOS:000384739900010
PM 26767381
DA 2026-07-24
ER

PT J
AU Söylemez, MS
   Özkan, K
   Kiliç, B
   Erinç, S
AF Soylemez, Mehmet Salih
   Ozkan, Korhan
   Kilic, Bulent
   Erinc, Samet
TI Intermittent negative pressure wound therapy with instillation for the
   treatment of persistent periprosthetic hip infections: a report of two
   cases
SO THERAPEUTICS AND CLINICAL RISK MANAGEMENT
LA English
DT Article
DE negative pressure; vacuum-assisted; periprosthetic infection; hip
ID VACUUM-SEALING-TECHNIQUE; JOINT INFECTIONS; CLOSURE
AB Intermittent negative pressure wound therapy with instillation (NPWTi) is starting to be used successfully to treat early periprosthetic infections of endoprostheses. However, few articles have reported the outcome of treatment with intermittent NPWTi for late persistent periprosthetic infections of the hip. In this study, we report two cases who underwent several rounds of radical wound debridement for the treatment of a late persistent periprosthetic infection of the hip. Intermittent NPWTi was used in both cases. Patients were treated successfully and there was no recurrence after 3 and 1 years of follow-up, respectively.
C1 [Soylemez, Mehmet Salih] Bingol State Hosp, Dept Orthopaed & Traumatol, Kulutr Mahallesi,Oguzhan Caddesi,22, TR-12000 Bingol, Turkey.
   [Ozkan, Korhan] Medeniyet Univ, Fac Med, Dept Orthopaed & Traumatol, Istanbul, Turkey.
   [Kilic, Bulent] Istanbul Gelisim Univ, Orthopaed Surg Clin, Dept Orthopaed & Traumatol, Tekirdag, Turkey.
   [Erinc, Samet] Istanbul Medeniyet Univ, Dept Orthopaed & Traumatol, Goztepe Training & Res Hosp, Istanbul, Turkey.
C3 Bingol State Hospital; Istanbul Medeniyet University; Istanbul Gelisim
   University; Istanbul Goztepe Training & Research Hospital; Istanbul
   Medeniyet University
RP Söylemez, MS (通讯作者)，Bingol State Hosp, Dept Orthopaed & Traumatol, Kulutr Mahallesi,Oguzhan Caddesi,22, TR-12000 Bingol, Turkey.
EM slhsylmz@gmail.com
RI ; Söylemez, Mehmet/AAZ-1399-2020; Kılıç, Bülent/ABB-2651-2021
OI erinç, samet/0000-0002-6494-6415; 
CR Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   Borgquist O, 2010, OSTOMY WOUND MANAG, V56, P60
   Bovill E, 2008, INT WOUND J, V5, P511, DOI 10.1111/j.1742-481X.2008.00437.x
   BROCK WB, 1995, AM SURGEON, V61, P30
   Fink B, 2009, INT J MED SCI, V6, P287
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Fleischmann W, 1998, UNFALLCHIRURG, V101, P649, DOI 10.1007/s001130050318
   Kelm J, 2009, INT J MED SCI, V6, P241
   Kirr R, 2006, ZBL CHIR, V131, pS79, DOI 10.1055/s-2005-921501
   Lehner B, 2006, ZBL CHIR, V131, pS160, DOI 10.1055/s-2006-921513
   Lessing MC, 2013, EPLASTY, V13, pe51
   Lüdemann M, 2006, Z ORTHOP GRENZGEB, V144, P602, DOI 10.1055/s-2006-942335
   Moch D, 1998, Langenbecks Arch Chir Suppl Kongressbd, V115, P1197
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Riepe G, 2006, ZBL CHIR, V131, pS157, DOI 10.1055/s-2006-921500
   Wolvos T, 2013, WOUNDS, V25, P75
NR 16
TC 14
Z9 16
U1 0
U2 4
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
SN 1178-203X
J9 THER CLIN RISK MANAG
JI Therap. Clin. Risk Manag.
PY 2016
VL 12
BP 161
EP 166
DI 10.2147/TCRM.S97930
PG 6
WC Health Care Sciences & Services
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services
GA DD4UE
UT WOS:000369917400001
PM 26929628
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Gallo, O
   Deganello, A
   Meccariello, G
   Spina, R
   Peris, A
AF Gallo, Oreste
   Deganello, Alberto
   Meccariello, Giuseppe
   Spina, Rosario
   Peris, Adriano
TI Vacuum-assisted closure for managing neck abscesses involving the
   mediastinum
SO LARYNGOSCOPE
LA English
DT Article
DE Neck abscess; mediastinitis; vacuum-assisted closure; infection
ID DESCENDING NECROTIZING MEDIASTINITIS; MANAGEMENT; INFECTION; SEPSIS
AB A 57-year-old immunocompetent male patient with a deep neck abscess involving the mediastinum was referred to us following unsuccessful treatment at his local hospital with medical therapy and ultrasound-guided aspiration. After initial evaluation and resuscitation, a contrast-enhanced computed tomography (CT) scan was performed, and the patient was transferred for surgical drainage. A vacuum-assisted closure (VAC) device was used as a surgical drain to help prevent reaccumulation of the purulent collections. A repeat CT scan on day 3 confirmed the absence of residual pus in the mediastinum and in the neck spaces, and the VAC device was removed. Perfect healing of the deep tissues with successful mediastinal toilette was observed. The patient resumed oral meals on postoperative day 10, and 2 days later he was discharged. A 1-month follow-up CT again demonstrated the complete healing and absence of the neck abscess. This case illustrates the possibility of avoiding more extensive and life-threatening procedures, such as open thoracotomy, in the treatment of neck abscesses extending into the mediastinum, and highlights the utility of VAC in the management of deep neck abscesses. Laryngoscope, 2012
C1 [Gallo, Oreste; Deganello, Alberto; Meccariello, Giuseppe] Univ Florence, Acad Clin Otolaryngol & Head Neck Surg, Dept Surg Sci, I-50134 Florence, Italy.
   [Spina, Rosario; Peris, Adriano] Careggi Teaching Hosp, Anaesthesia & Intens Care Unit Emergency Dept, Florence, Italy.
C3 University of Florence; University of Florence; Azienda Ospedaliero
   Universitaria Careggi
RP Gallo, O (通讯作者)，Univ Florence, Acad Clin Otolaryngol & Head Neck Surg, Dept Surg Sci, Viale Morgagni 85, I-50134 Florence, Italy.
EM o.gallo@med.unifi.it
RI ; Meccariello, Giuseppe/K-5685-2016; DEGANELLO, ALBERTO/I-2742-2014
OI Gallo, Oreste/0000-0003-3426-7179; Meccariello,
   Giuseppe/0000-0001-7753-4615; DEGANELLO, ALBERTO/0000-0003-1008-7333
CR Andrews BT, 2008, ANN OTO RHINOL LARYN, V117, P298, DOI 10.1177/000348940811700410
   Batacchi S, 2009, CRIT CARE, V13, DOI 10.1186/cc8193
   Daramola OO, 2009, OTOLARYNG HEAD NECK, V141, P123, DOI 10.1016/j.otohns.2009.03.033
   Deganello A, 2009, ACTA OTORHINOLARYNGO, V29, P160
   Dellinger RP, 2008, CRIT CARE MED, V36, P296, DOI 10.1097/01.CCM.0000298158.12101.41
   Dhir K, 2009, LARYNGOSCOPE, V119, P54, DOI 10.1002/lary.20000
   DURANDY Y, 1989, J THORAC CARDIOV SUR, V97, P282
   Ferguson D A Jr, 1992, Microbios, V69, P53
   Huang TT, 2004, HEAD NECK-J SCI SPEC, V26, P854, DOI 10.1002/hed.20014
   Islam Asad, 2008, J Med Case Rep, V2, P368, DOI 10.1186/1752-1947-2-368
   Min HK, 2004, ANN THORAC SURG, V77, P306, DOI 10.1016/S0003-4975(03)01333-X
   Parhiscar A, 2001, ANN OTO RHINOL LARYN, V110, P1051, DOI 10.1177/000348940111001111
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   Saadi A, 2011, ANN THORAC SURG, V91, P1582, DOI 10.1016/j.athoracsur.2011.01.018
   Singhal P, 2008, HEART LUNG CIRC, V17, P124, DOI 10.1016/j.hlc.2007.08.004
   Wang LF, 2003, AM J OTOLARYNG, V24, P111, DOI 10.1053/ajot.2003.31
NR 16
TC 26
Z9 30
U1 0
U2 4
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 0023-852X
J9 LARYNGOSCOPE
JI Laryngoscope
PD APR
PY 2012
VL 122
IS 4
BP 785
EP 788
DI 10.1002/lary.22403
PG 4
WC Medicine, Research & Experimental; Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Otorhinolaryngology
GA 911KD
UT WOS:000301714800016
PM 22252529
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Wu, ML
   Sun, MY
   Dai, HY
   Xu, JG
   Wang, XW
   Guo, R
   Wang, YC
   Xue, CY
AF Wu, Minliang
   Sun, Mengyan
   Dai, Haiying
   Xu, Jianguo
   Wang, Xinwei
   Guo, Rui
   Wang, Yuchong
   Xue, Chunyu
TI The application of keystone flap combined with vacuum-assisted closure
   in the repair of sacrococcygeal skin defect after tumor resection
SO JOURNAL OF SURGICAL ONCOLOGY
LA English
DT Article
DE keystone design perforator island flap; sacrococcygeal region; tumor;
   vacuum-assisted closure; wound repair
ID ISLAND FLAP; BLOOD-FLOW; PERFORATOR; THERAPY
AB ObjectiveWe aimed to explore the efficacy of keystone flap combined with vacuum-assisted closure (VAC) in the repair of sacrococcygeal wounds.
   MethodsThis study is a retrospective review of patients undergoing keystone flap reconstruction between January 2014 and January 2018. A standardized data collection template was used to collect related variables. The detailed process of the reconstructive surgery is carefully described in this study. The postoperative healing process was closely observed.
   ResultsTwelve patients underwent keystone flap repair between January 2014 and January 2018. The average wound size before closure measured 7.831.93x 5.28 +/- 0.91cm. All the patients achieved primary wound healing and the flaps survived during the follow-up period, which ranged from 1 to 24 months. No severe complications and obvious scar appeared, and the patients were satisfied with both appearance and function.
   ConclusionsThe application of keystone flap combined with VAC is a promising way to repair wounds in the sacrococcygeal region with little postoperative complication and similar soft-tissue thickness to the surrounding tissue.
C1 [Wu, Minliang; Sun, Mengyan; Dai, Haiying; Xu, Jianguo; Wang, Xinwei; Guo, Rui; Wang, Yuchong; Xue, Chunyu] Second Mil Med Univ, Changhai Hosp, Dept Plast Surg, 168 Changhai Rd, Shanghai 200433, Peoples R China.
C3 Naval Medical University
RP Wang, YC; Xue, CY (通讯作者)，Second Mil Med Univ, Changhai Hosp, Dept Plast Surg, 168 Changhai Rd, Shanghai 200433, Peoples R China.
EM drwangyc@163.com; xcyfun@sina.com
RI ; Wu, Minliang/GPT-4264-2022; xu, jianguo/JZD-9552-2024
OI 王, 宇翀/0000-0001-5094-5553; 
CR [Anonymous], COCHRANE DATABASE SY
   Behan F, 2003, ANZ J SURG, V73, P112, DOI 10.1046/j.1445-2197.2003.02638.x
   Behan F, 2006, ANZ J SURG, V76, P407, DOI 10.1111/j.1445-2197.2006.03708.x
   Behan FC, 2013, J PLAST RECONSTR AES, V66, P23, DOI 10.1016/j.bjps.2012.08.027
   Borgquist O, 2010, PLAST RECONSTR SURG, V125, P502, DOI 10.1097/PRS.0b013e3181c82e1f
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   Douglas CD, 2013, ANN SURG ONCOL, V20, P973, DOI 10.1245/s10434-012-2684-9
   Fleischmann W, 1997, UNFALLCHIRURG, V100, P301, DOI 10.1007/s001130050123
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   Kosaka M, 2004, PLAST RECONSTR SURG, V113, P1884, DOI 10.1097/01.PRS.0000119882.31318.EF
   Liu X, 2017, MEDICINE, V96, pe8916
   Mohan AT, 2016, PLAST RECONSTR SURG, V138, p710E, DOI 10.1097/PRS.0000000000002610
   Mohan AT, 2016, PLAST RECONSTR SURG, V137, P1909, DOI 10.1097/PRS.0000000000002228
   Mouës CM, 2011, AM J SURG, V201, P544, DOI 10.1016/j.amjsurg.2010.04.029
   Park HS, 2016, ANN PLAS SURG, V77, P332, DOI 10.1097/SAP.0000000000000600
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   Stone JP, 2015, PLAST RECONSTR SURG, V136, P404, DOI 10.1097/PRS.0000000000001449
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   Xia CY, 2014, MOL MED REP, V9, P1749, DOI 10.3892/mmr.2014.1997
NR 20
TC 6
Z9 7
U1 0
U2 4
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0022-4790
EI 1096-9098
J9 J SURG ONCOL
JI J. Surg. Oncol.
PD JUN
PY 2019
VL 119
IS 7
BP 974
EP 978
DI 10.1002/jso.25397
PG 5
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA IK9TK
UT WOS:000476938900021
PM 30714165
DA 2026-07-24
ER

PT J
AU Rocco, G
   Cecere, C
   La Rocca, A
   Martucci, N
   Salvi, R
   Passera, E
   Cicalese, M
AF Rocco, Gaetano
   Cecere, Ciriaco
   La Rocca, Antonello
   Martucci, Nicola
   Salvi, Rosario
   Passera, Eliseo
   Cicalese, Marcellino
TI Caveats in using vacuum-assisted closure for post-pneumonectomy empyema
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article
DE Vacuum assisted closure; Pneumonectomy; Empyema; Bronchopleural fistula
ID BRONCHOPLEURAL FISTULA; MANAGEMENT; DEVICE
AB Vacuum-assisted closure (VAC) of chronic empyemas can potentially set challenging patients free of prolonged hospitalization by warranting outpatient care. We wanted to test this concept in post-pneumonectomy empyema patients.
   Three patients with post-pneumonectomy bronchopleural fistula were subjected to open window thoracostomy (OWT) and subsequently to VAC. The BPFs were closed by endobronchial stents in 2 of the patients. The VAC system was applied at a median time of 35 days (range, 23-113) after pneumonectomy. The patients were scheduled for outpatient visits every three days with complete change of the VAC sponges.
   Hypotension and acute thoracic pain despite minimal suction applied to the VAC sponges were observed during treatment and eventually caused VAC discontinuation. In one patient, the sponges of the VAC system could not be directly removed through the OWT and careful dissection through VATS under deep sedation was needed.
   VAC can be of help to obliterate the post-pneumonectomy empyema cavity but its use can trigger clinically significant complications. Cautious monitoring of the VAC system must be exercised in the early period prior to discharging patients to the outpatient clinic.
C1 [Rocco, Gaetano; La Rocca, Antonello; Martucci, Nicola; Salvi, Rosario; Passera, Eliseo; Cicalese, Marcellino] Pascale Fdn, Natl Canc Inst, Dept Thorac Surg & Oncol, Div Thorac Surg, I-80131 Naples, Italy.
   [Cecere, Ciriaco] Univ Naples Federico 2, Dept Thorac Surg, Naples, Italy.
C3 IRCCS Fondazione Pascale; University of Naples Federico II
RP Rocco, G (通讯作者)，Pascale Fdn, Natl Canc Inst, Dept Thorac Surg & Oncol, Div Thorac Surg, Via Semmola 81, I-80131 Naples, Italy.
EM gaetano.rocco@btopenworld.com
RI Rocco, Gaetano/K-4801-2016
OI Rocco, Gaetano/0000-0003-4150-8604
CR Aru GM, 2010, ANN THORAC SURG, V90, P266, DOI 10.1016/j.athoracsur.2010.04.092
   Hazelrigg Stephen R, 2010, Ann Thorac Surg, V90, P270, DOI 10.1016/j.athoracsur.2010.05.026
   Jones NC, 2006, ANN THORAC SURG, V81, P364, DOI 10.1016/j.athoracsur.2004.09.054
   Massera F, 2006, ANN THORAC SURG, V82, P288, DOI 10.1016/j.athoracsur.2005.11.046
   Passera E, 2011, ANN THORAC SURG, V92, pE23, DOI 10.1016/j.athoracsur.2011.03.047
   Schneiter D, 2008, J THORAC CARDIOV SUR, V136, P179, DOI 10.1016/j.jtcvs.2008.01.036
   Varker KA, 2006, ANN THORAC SURG, V81, P723, DOI 10.1016/j.athoracsur.2004.10.040
NR 7
TC 17
Z9 23
U1 0
U2 5
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD MAY
PY 2012
VL 41
IS 5
BP 1069
EP 1071
DI 10.1093/ejcts/ezr196
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 930TA
UT WOS:000303161800032
PM 22219471
OA Bronze
DA 2026-07-24
ER

PT J
AU Fischer, JE
AF Fischer, Josef E.
TI A cautionary note: the use of vacuum-assisted closure systems in the
   treatment of gastrointestinal cutaneous fistula may be associated with
   higher mortality from subsequent fistula development
SO AMERICAN JOURNAL OF SURGERY
LA English
DT Editorial Material
DE gastrointestinal cutaneous fistula; mortality; vacuum-assisted closure
   systems
ID FASCIAL CLOSURE; ABDOMINAL WOUNDS; VENTRAL HERNIA; PACK TECHNIQUE; OPEN
   ABDOMENS; TRAUMA
AB During the past several years, vacuum-assisted closure (VAC) systems have been increasingly used in the treatment of gastrointestinal cutaneous fistulas, particularly those associated with open abdomen. Recently, I experienced 2 cases in which the original fistula closed after treatment by the VAC system. However, these patients, who had exposed bowel, developed an additional fistula that required Surgery. In a recent article from ail intestinal-failure unit in the United Kingdom, Rao et al(1) reported on a series of 29 patients treated with VAC, 6 of whom developed new gastrointestinal cutaneous fistulas. Four of these 6 patients died. My own experiences, plus the report of Rao et al,(1) suggest the possibility that the use of the VAC system in patients with exposed bowel and all open abdomen may be associated with subsequent fistula development. Although the numbers are small, it also raises the question that development of a fistula in a patient treated with VAC may result in higher mortality. (c) 2008 Elsevier Inc. All rights reserved.
C1 Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Surg, Boston, MA 02215 USA.
C3 Harvard University; Harvard Medical School; Harvard University Medical
   Affiliates; Beth Israel Deaconess Medical Center
RP Fischer, JE (通讯作者)，Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Surg, Boston, MA 02215 USA.
EM fische1@bidmc.harvard.edu
CR Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
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NR 7
TC 60
Z9 70
U1 0
U2 2
PU EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
PI BRIDGEWATER
PA 685 ROUTE 202-206 STE 3, BRIDGEWATER, NJ 08807 USA
SN 0002-9610
J9 AM J SURG
JI Am. J. Surg.
PD JUL
PY 2008
VL 196
IS 1
BP 1
EP 2
DI 10.1016/j.amjsurg.2008.01.001
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 320CM
UT WOS:000257211300001
PM 18355795
DA 2026-07-24
ER

PT J
AU Azzopardi, EA
   Boyce, DE
   Dickson, WA
   Azzopardi, E
   Laing, JHE
   Whitaker, IS
   Shokrollahi, K
AF Azzopardi, Ernest Anthony
   Boyce, Dean E.
   Dickson, William A.
   Azzopardi, Elayne
   Laing, James Hamish Ellsworth
   Whitaker, Iain S.
   Shokrollahi, Kayvan
TI Application of Topical Negative Pressure (Vacuum-Assisted Closure) to
   Split-Thickness Skin Grafts A Structured Evidence-Based
   Review
SO ANNALS OF PLASTIC SURGERY
LA English
DT Review
DE topical negative pressure; VAC; negative pressure wound therapy;
   split-thickness skin graft
ID SIGNAL-TRANSDUCTION; THERAPY; PROLIFERATION; BOLSTER
AB Introduction: Significant controversy surrounds the effectiveness of negative pressure wound therapy although it has been in use for decades. Although many clinicians favor this modality in relation to its practicality, ease of use especially in complex wounds, it has faced the same challenges as other dressings in relation to evidence base of efficacy in relation to a number of outcome measures. In view of the current financial pressures on health care systems worldwide, this structured review systematically challenges the evidence for perioperative application of topical negative pressure (TNP) to split-thickness skin grafts (STSGs) through evidence-based critical appraisal, and extrapolate the mechanisms of action on the mechanisms through which TNP may aid wound healing. Weighted evidence-based recommendations regarding the impact of TNP on split skin graft quality and quantity of take as outcomes.
   Methods: Phase 1: Structured literature search. Phase 2: Retrieved articles were critically appraised for rigor and methodological validity by 3 independent authors, then stratified according to a validated "levels of evidence" framework. Graded "current best evidence" recommendations could therefore be proposed.
   Results: Of the 220 studies retrieved in the initial search, 38 studies satisfied our quality of evidence criteria. Current best evidence supports 2 complementary trends explaining the mechanisms whereby STSG benefits from TNP. Active stimulation of epithelial mitosis: TNP creates mechanical stretch which stimulates multiple signaling pathways up-regulating growth-and mitosis-associated epithelial transcription factors. Topical negative pressure also promotes microcirculatory flow (graft and wound edge), stimulates angiogenesis and basement membrane integrity (grade C). Prevention of complications: significant reduction of graft lift-off by edema, exudates, subgraft hematoma, and reduction of shear when compared to traditional dressings (grade B). Topical negative pressure promotes significant qualitative improvement in the final STSG result studies (level 1B). The role of TNP in prevention of infection is, however, equivocal and further research is required. No evidence of harm from TNP application was reported.
   Conclusions: Topical negative pressure increases quantity and quality of split skin graft take compared to traditional bolster dressings. The advantages are increased in irregularly contoured, technically difficult wounds and suboptimal recipient wound beds where it seems to be the best modality currently available. Large-scale randomized clinical controlled trials remain scanty in all areas of wound dressing research including negative pressure therapy.
C1 [Azzopardi, Ernest Anthony; Boyce, Dean E.; Dickson, William A.; Laing, James Hamish Ellsworth; Whitaker, Iain S.; Shokrollahi, Kayvan] Morriston Hosp, Welsh Ctr Burns & Plast Surg, Swansea, W Glam, Wales.
   [Azzopardi, Ernest Anthony] Cardiff Univ, Sch Dent, Cardiff, S Glam, Wales.
   [Azzopardi, Elayne] Manchester Metropolitan Univ, Fac Hlth Psychol & Social Care, Res Inst Hlth & Social Change, Manchester M15 6BH, Lancs, England.
   [Azzopardi, Elayne] Whiston Hosp, Mersey Reg Burns & Plast Surg Unit, Liverpool, Merseyside, England.
C3 Morriston Hospital; Cardiff University; Manchester Metropolitan
   University; Whiston Hospital
RP Shokrollahi, K (通讯作者)，Morriston Hosp, Welsh Ctr Burns & Plast Surg, Swansea, W Glam, Wales.
EM kshokrollahi@hotmail.com
RI Whitaker, Iain/O-5896-2019; Laing, Hamish/AAN-3921-2020; Shokrollahi,
   Kayvan/V-4993-2019; /AAE-2342-2021
OI Whitaker, Iain/0000-0002-3922-2079; Laing, Hamish/0000-0002-5661-7937;
   Azzopardi, Ernest/0000-0002-4511-0954; Shokrollahi,
   Kayvan/0000-0003-1044-7781; 
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NR 48
TC 59
Z9 75
U1 0
U2 24
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD JAN
PY 2013
VL 70
IS 1
BP 23
EP 29
DI 10.1097/SAP.0b013e31826eab9e
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 056KJ
UT WOS:000312487400006
PM 23249474
DA 2026-07-24
ER

PT J
AU Danne, J
   Gwini, S
   McKenzie, D
   Danne, P
AF Danne, Julia
   Gwini, Stella
   McKenzie, Dean
   Danne, Peter
TI A Retrospective Study of Pilonidal Sinus Healing by Secondary Intention
   Using Negative Pressure Wound Therapy Versus Alginate or Gauze Dressings
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE retrospective study; wound healing; pilonidal sinus; negative pressure
   wound therapy; dressing
ID VACUUM-ASSISTED CLOSURE; DISEASE
AB Pilonidal sinus (PS) disease is an inflammatory skin and subcutaneous tissue condition that presents with infection, acute abscess, chronic discharging wounds, and/or pain. Surgery with open healing by secondary intention typically is used to achieve the fastest healing time with minimal recurrence rates. A retrospective analysis was conducted of data extracted from the medical records of 73 consecutive patients who had symptomatic natal cleft PS over a 10-year period to compare use of NPWT to alginate-based/gauze daily dressing (DD) changes in terms of healing time and recurrence. Variables extracted included age, gender, PS wound diameter (small <1 cm, medium 1 cm to 3 cm, large >3 cm), and time in weeks to achieving the endpoint (epithelialization). Risk factors examined that can affect healing or recurrence of previously operated PS disease included initial drainage before excision and risk factors for impaired healing (morbid obesity as determined by body mass index [BMI] >= 35, chronic infective skin conditions, and ongoing therapy with immuno-modulating drugs or chemotherapy), and loss to follow-up. Data were collected and analyzed using the chi-squared statistic, Kaplan-Meier curves, and Cox regression models. The total time of follow-up was 390 weeks for the DD group and 311 weeks for NPWT group. Patient mean age was 26.5 +/- 10.7 years, most (53, 72.6%) were male, and 12 (16.4%) had comorbidities potentially affecting healing. Nine (9) were treated with primary closure and 62 patients were treated with open healing by secondary intention (2 additional patients receiving DD were excluded from the analysis because they had small sinuses that made NPWT unfeasible). Among participants, 30 (48%) received DD and 32 had NPWT. The median time to healing was 10 weeks (95% CI: 7-17) in the DD group and 8 weeks (95% CI: 7-9) in the NPWT group (not significantly different). In patients who healed, the average time to healing was 15.0 +/- 18.1 and 9.8 +/- 6.3 weeks in the DD and NPWT groups, respectively (not significantly different). The PS wound recurred in 5 patients -4 (12.5%) in the DD group and 1 (3.1%) in the NPWT group (P =.355). In univariate analysis, only the presence of comorbidities was found to significantly affect time to healing (HR 95%, CI: 0.40 [0.17-0.93]; P =.033]. Prospective, randomized controlled clinical studies are warranted.
C1 [Danne, Julia] St Vincents Hosp Melbourne, Melbourne, Vic, Australia.
   [Danne, Peter] General Trauma Surgeon Epworth Healthcare, Richmond, Australia.
C3 St Vincent's Health; St Vincent's Hospital Melbourne
RP Danne, J (通讯作者)，Epworth Ctr, Suite 8,Level 8,32 Erin St, Richmond, Vic 3121, Australia.
EM juliadanne@hotmail.com
RI Gwini, Stella/AAI-8648-2021
OI Gwini, Stella/0000-0002-0295-4575
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NR 21
TC 17
Z9 18
U1 0
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD MAR
PY 2017
VL 63
IS 3
BP 47
EP 53
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EQ5MZ
UT WOS:000398128200003
PM 28355137
DA 2026-07-24
ER

PT J
AU Tuncel, U
   Erkorkmaz, Ü
   Turan, A
AF Tuncel, Umut
   Erkorkmaz, Unal
   Turan, Aydin
TI Clinical evaluation of gauze-based negative pressure wound therapy in
   challenging wounds
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Challenging wounds; Gauze; Negative pressure; Wound care; Wound filler
ID VACUUM-ASSISTED CLOSURE; DOUBLE-BLIND; EXPERIENCE; TRANSDUCTION;
   POLYHEXANIDE; ULCERS; IMPACT; FLAPS; FOAM
AB The aim of this randomised clinical study was to evaluate the effectiveness and safety of gauze-based negative pressure wound therapy (NPWT) in patients with challenging wounds. A total of 50 consecutive patients who had wound drainage for more than 5 days, required open wound management and had existence of culture positive infection were included the study. In this study, gauze-based NPWT was compared with conventional dressing therapy in the treatment of patients with difficult-to-heal wounds. The patients were randomly divided into two groups. Group I (n = 25) was followed by conventional antiseptic (polyhexanide solution) dressings, and group II (n = 25) was treated with saline-soaked antibacterial gauze-based NPWT. The wounds' sizes, number of debridement, bacteriology and recurrence were compared between group I and group II. The mean age of the patients was 59 center dot 50 years (range 2397). In group I, average wound sizes of pre- and post-treatment periods were 50 center dot 60 +/- 55 center dot 35 and 42 center dot 50 +/- 47 center dot 92 cm2, respectively (P < 0 center dot 001). Average duration of treatment was 25 center dot 52 +/- 16 center dot 99 days, and average wound size reduction following the treatment was 19 center dot 99% in this group. In group II, the wounds displayed considerable shrinkage, accelerated granulation tissue formation, decreased and cleared away exudate. The average wound sizes in the pre- and post-treatment periods were 98 center dot 44 +/- 100 center dot 88 and 72 center dot 08 +/- 75 center dot 78 cm2, respectively (P < 0 center dot 001). Average duration of treatment was 11 center dot 96 +/- 2 center dot 48 days, and average wound size reduction following the treatment was 32 center dot 34%. The patients treated with antibacterial gauze-based NPWT had a significantly reduced recurrence (2 wounds versus 14 wounds, P = 0 center dot 001), and increased number of the culture-negative cases (22 wounds versus 16 wounds, P < 0 center dot 047) in a follow-up period of 12 months. There was a statistically significant difference between two groups in all measurements. As a result, we can say that the gauze-based NPWT is a safe and effective method in the treatment of challenging infective wounds when compared with conventional wound management.
C1 [Tuncel, Umut; Turan, Aydin] Gaziosmanpasa Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-60150 Tokat, Turkey.
   [Erkorkmaz, Unal] Gaziosmanpasa Univ, Fac Med, Dept Biostat, TR-60150 Tokat, Turkey.
C3 Tokat Gaziosmanpasa University; Tokat Gaziosmanpasa University
RP Tuncel, U (通讯作者)，Gaziosmanpasa Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-60150 Tokat, Turkey.
EM drumuttuncel@gmail.com
RI Tuncel, Umut/P-3185-2015; Erkorkmaz, Ünal/AAA-4241-2022; Turan,
   Aydın/V-6669-2017
OI Tuncel, Umut/0000-0001-5029-2927; Erkorkmaz, Ünal/0000-0002-8497-4704;
   Turan, Aydın/0000-0002-1540-1443
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NR 30
TC 20
Z9 21
U1 0
U2 12
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2013
VL 10
IS 2
BP 152
EP 158
DI 10.1111/j.1742-481X.2012.00955.x
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 112DB
UT WOS:000316571100007
PM 22420837
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Sivash, II
   Koval, BM
AF Sivash, Iurii I.
   Koval, Boris M.
TI Negative pressure wound therapy for combat-related extremity vascular
   injuries: clinical experience from the war in Ukraine
SO SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE
LA English
DT Article
DE NPWT; Combat extremity vascular trauma; Limb salvage; Soft-tissue
   defect; War in Ukraine
ID VACUUM-ASSISTED CLOSURE; INFECTIOUS COMPLICATIONS; MANAGEMENT; IRAQ;
   EPIDEMIOLOGY; FRACTURES; SURGERY; GRAFT
AB BackgroundExtremity vascular injuries are among the most challenging problems in military surgery. They are frequently accompanied by extensive soft tissue loss and heavy contamination, which increases the risk of infection and limb loss. Although negative pressure wound therapy (NPWT) is widely used in civilian practice, its role in combat vascular injuries remains unclear. The war in Ukraine provided an opportunity to evaluate NPWT as part of staged surgical care under modern battlefield conditions.MethodsWe retrospectively reviewed 85 service members with severe combat-related extremity vascular injuries admitted to a Role IV facility in 2022. Among these patients, 69/85 (81.2%) had extensive soft-tissue defects overlying vascular reconstructions and received NPWT; this subgroup constituted the analytic cohort. A standardised two-layer NPWT technique was used: an inner nonadherent barrier/PVA sponge directly over the reconstruction site and an outer polyurethane foam connected to continuous -70 to -80 mmHg. The dressing was changed every 3-4 days. The outcomes included infectious complications, erosion-related bleeding, arterial thrombosis, secondary amputation, the method of definitive wound closure, and the length of stay.ResultsThe mechanisms of injury were mine blast (71%), gunshot (23%), and other explosive trauma (6%). Combined arterial-venous injuries occurred in 40% (n = 28/69), fractures in 42% (n = 29/69), and primary wound contamination in 57% (n = 39/69) of the patients. Definitive closure was achieved by primary approximation in 75.4% (n = 52/69), skin grafting in 17.4% (n = 12/69), and flap techniques in 4.3% (n = 3/69). Complications occurred in 27.5% (n = 19/69): erosion-related bleeding (13%, n = 9/69), arterial thrombosis (8.7%, n = 6/69), and infection (5.8%, n = 4/69). Erosion-related bleeding clustered in two risk windows: days 7-10 and 18-30. Secondary amputation was required in 2.9% (n = 2/69); in-hospital mortality was 0%.ConclusionsA two-layer NPWT protocol at -70 to -80 mmHg was a safe and effective adjunct in the staged management of combat-related extremity vascular injuries with extensive soft-tissue defects. This approach is associated with the preservation of vascular reconstructions and limbs, low infection and amputation rates, the mitigation of erosion-related bleeding, and timely wound closure. Prospective multicenter studies are needed to optimise and standardise NPWT protocols in this setting.
C1 [Sivash, Iurii I.; Koval, Boris M.] Natl Mil Med Clin Ctr, Main Mil Clin Hosp, Kiev, Ukraine.
   [Sivash, Iurii I.; Koval, Boris M.] Bogomolets Natl Med Univ, Kiev, Ukraine.
C3 Bogomolets National Medical University
RP Sivash, II (通讯作者)，Natl Mil Med Clin Ctr, Main Mil Clin Hosp, Kiev, Ukraine.; Sivash, II (通讯作者)，Bogomolets Natl Med Univ, Kiev, Ukraine.
EM y.sivash@gmail.com; kovalboris@gmail.com
OI Sivash, Iurii/0000-0002-7956-6378
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NR 45
TC 1
Z9 3
U1 2
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1757-7241
J9 SCAND J TRAUMA RESUS
JI Scand. J. Trauma Resusc. Emerg. Med.
PD NOV 25
PY 2025
VL 33
IS 1
AR 188
DI 10.1186/s13049-025-01502-3
PG 12
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA E5141
UT WOS:001622613000001
PM 41291788
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Banasiewicz, T
   Borejsza-Wysocki, M
   Meissner, W
   Malinger, S
   Szmeja, J
   Koscinski, T
   Ratajczak, A
   Drews, M
AF Banasiewicz, Tomasz
   Borejsza-Wysocki, Maciej
   Meissner, Wiktor
   Malinger, Stanislaw
   Szmeja, Jacek
   Koscinski, Tomasz
   Ratajczak, Andrzej
   Drews, Michal
TI Vacuum-assisted closure therapy in patients with large postoperative
   wounds complicated by multiple fistulas
SO VIDEOSURGERY AND OTHER MINIINVASIVE TECHNIQUES
LA English
DT Article
DE vacuum-assisted closure (VAC) therapy; topical negative pressure;
   enterocutaneous fistula
ID ENTEROCUTANEOUS FISTULAS; ABDOMINAL WOUNDS; CLINICAL-EXPERIENCE; OPEN
   ABDOMEN; SYSTEM; MANAGEMENT; PRESSURE; TRIAL
AB Vacuum-assisted closure (VAC) therapy is a widely acknowledged method for chronic and traumatic wound healing. The feasibility of VAC therapy used for the treatment of intestinal fistulas is still a subject of debate. Complex postoperative wounds pose significant therapeutic problems, especially when there are several fistula openings in the wound area and other sites, usually at the site of previous drains. This paper describes the treatment of three patients in a critical condition, with complex postoperative wounds complicated by multiple fistulas. Vacuum-assisted closure therapy was based on effective drainage of the biggest fistula opening and ensuring conditions promoting the healing process of other fistulas and the wound. A considerable improvement in general condition and wound healing was noted within 2-4 weeks and both the number of fistulas and the volume of excreted contents decreased. After 5-7 weeks a significant improvement in wound healing was observed in all patients. Once the general condition of all patients was considered satisfactory (2-6 months), they underwent surgery aimed at restoration of the digestive tract continuity In our opinion, VAC therapy used for the treatment of postoperative wounds with multiple fistulas in the wound area and other sites should aim mainly at the improvement of patients' general condition, limitation of the number of fistulas as well as accelerated wound healing. This may lead to formation of one stoma-type fistula, which can be dressed and cared for by patients until the continuity of the digestive tract has been surgically restored.
C1 [Banasiewicz, Tomasz; Borejsza-Wysocki, Maciej; Meissner, Wiktor; Malinger, Stanislaw; Szmeja, Jacek; Koscinski, Tomasz; Ratajczak, Andrzej; Drews, Michal] Poznan Univ Med Sci, Dept Gen Gastroenterol & Endocrine Surg, PL-60355 Poznan, Poland.
C3 Poznan University of Medical Sciences
RP Banasiewicz, T (通讯作者)，Poznan Univ Med Sci, Dept Gen Gastroenterol & Endocrinol Surg, 49 Przybyszewskiego, PL-60355 Poznan, Poland.
EM tbanasiewicz@op.pl
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NR 30
TC 24
Z9 31
U1 0
U2 5
PU TERMEDIA PUBLISHING HOUSE LTD
PI POZNAN
PA WENEDOW ST 9-1, POZNAN, 61-614, POLAND
SN 1895-4588
J9 VIDEOSURGERY MINIINV
JI Videosurgery Miniinvasive Tec.
PY 2011
VL 6
IS 3
BP 155
EP 163
DI 10.5114/wiitm.2011.24694
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 829IV
UT WOS:000295572700007
PM 23255975
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Leffler, M
   Horch, RE
   Dragu, A
   Bach, AD
AF Leffler, M.
   Horch, R. E.
   Dragu, A.
   Bach, A. D.
TI The use of the artificial dermis (Integra®) in combination with vacuum
   assisted closure for reconstruction of an extensive burn scar - A case
   report
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article; Proceedings Paper
CT Congress of the
   German-and-Austrian-Society-of-Plastic-Reconstructive-and-Aesthetic-Surg
   eons
CY OCT 02-04, 2008
CL Stuttgart, GERMANY
SP DGPRAC, VDAPC, OGPARC
DE Burn; Skin gafting; Artifical dermis; Topical negative pressure
ID NEGATIVE-PRESSURE
AB The artificial dermis Integra (R) (Ethicon (R), Johnson & Johnson Medical, Norderstedt, Germany) is widely used in the treatment of excessive burn injuries. It is also used in reconstructive surgery when large soft-tissue defects could not be covered with local or free flaps. In this article a 25-year old patient who presented with an early childhood burn of the trunk and lower extremity was treated with Integra (R) in combination with the vacuum assisted closure (V.A.C.(R), KCI, Texas, U.S.A.) and split thickness skin grafting. The combination of the artifical dermal substitute with negative pressure therapy has lead to a complete healing of Integra (R) and the skin graft. During the whole treatment sterile wound conditions were present and time-consuming dressing changes could be prevented. Hospital stay was shortened because the patient could be treated as an outpatient with an ambulant vacuum assisted closure device. (C) 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Leffler, M.; Horch, R. E.; Dragu, A.; Bach, A. D.] Univ Hosp Erlangen, Dept Plast & Hand Surg, D-91054 Erlangen, Germany.
C3 University of Erlangen Nuremberg
RP Leffler, M (通讯作者)，Univ Hosp Erlangen, Dept Plast & Hand Surg, Krankenhausstr 12, D-91054 Erlangen, Germany.
EM Mareike.Leffler@uk-erlangen.de
RI Horch, Raymund E/H-8128-2019; Dragu, Adrian/AAH-3506-2019
OI Horch, Raymund E/0000-0002-6561-2353; Dragu, Adrian/0000-0003-4633-2695
CR BURKE JF, 1981, ANN SURG, V194, P413, DOI 10.1097/00000658-198110000-00005
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   Unglaub F, 2005, ZBL CHIR, V130, P157, DOI 10.1055/s-2005-836367
NR 5
TC 32
Z9 35
U1 0
U2 15
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD JAN
PY 2010
VL 63
IS 1
BP E32
EP E35
DI 10.1016/j.bjps.2009.05.022
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 536YA
UT WOS:000273078600041
PM 19523890
DA 2026-07-24
ER

PT J
AU Conquest, AM
   Garofalo, JH
   Maziarz, DM
   Mendelson, MG
   Sun, YS
   Wooden, WA
   Meadows, WM
   Nifong, W
   Chitwood, WR
AF Conquest, AM
   Garofalo, JH
   Maziarz, DM
   Mendelson, MG
   Sun, YS
   Wooden, WA
   Meadows, WM
   Nifong, W
   Chitwood, WR
TI Hemodynamic effects of the vacuum-assisted closure device on open
   mediastinal wounds
SO JOURNAL OF SURGICAL RESEARCH
LA English
DT Article; Proceedings Paper
CT 36th Annual Meeting of the Association-for-Academic-Surgery
CY NOV 07-09, 2002
CL BOSTON, MASSACHUSETTS
SP Assoc Acad Surg
DE vacuum-assisted closure device; post-sternotomy wound infection; open
   mediastinal wounds
AB Background. Application of the Vacuum-Assisted Closure device (VAC to open sternal wounds has negative hemodynamic effects. We hypothesized that the interposition of a muscle flap attenuates these negative hemodynamic effects.
   Materials and methods. After institutional approval, monitoring lines were placed in anesthetized, ventilated pigs. Through a median sternotomy, sonometric crystals were strategically positioned around the left ventricle. A rectus flap was rotated over the mediastinal wound, and the VAC was placed over the flap. After baseline measurements, a vacuum of 125 mmHg [Group (GP) 1, n = 51 or 50 mmHg (GP2, n = 6) was initiated. Hemodynamics were recorded every 15 min for 1.5 h, and 15 min after cessation of the vacuum therapy. GP3 (n = 6) underwent intermittent VAC cycling (on 5 min/off 2 min). Significance determined by t test.
   Results. While non-flapped animals had significant detriment in both left ventricular filling volume and cardiac output, flapped animals had insignificant depression of both parameters.
   Conclusion. Application of muscle flaps to sternal wounds prior to VAC therapy significantly attenuates the negative hemodynamic effects seen when the VAC is used alone. (C) 2003 Elsevier Inc. All rights reserved.
C1 E Carolina Univ, Brody Sch Med, Dept Surg, Greenville, NC 27858 USA.
   Univ S Florida, Tampa, FL USA.
C3 University of North Carolina; East Carolina University; State University
   System of Florida; University of South Florida
RP Conquest, AM (通讯作者)，E Carolina Univ, Brody Sch Med, Dept Surg, 600 Moye Blvd,TA Room 301, Greenville, NC 27858 USA.
EM conquesta@mail.ecu.edu
CR Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
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   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
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NR 7
TC 29
Z9 43
U1 0
U2 1
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0022-4804
J9 J SURG RES
JI J. Surg. Res.
PD DEC
PY 2003
VL 115
IS 2
BP 209
EP 213
DI 10.1016/S0022-4804(03)00331-7
PG 5
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 761JN
UT WOS:000187866900006
PM 14697285
DA 2026-07-24
ER

PT J
AU Baucom, MR
   Wallen, TE
   Youngs, J
   Singer, KE
   Delman, AM
   Schuster, RM
   Blakeman, TC
   Strilka, R
   Pritts, TA
   Goodman, MD
AF Baucom, Matthew R.
   Wallen, Taylor E.
   Youngs, Jaclyn
   Singer, Kathleen E.
   Delman, Aaron M.
   Schuster, Rebecca M.
   Blakeman, Thomas C.
   Strilka, Richard
   Pritts, Timothy A.
   Goodman, Michael D.
TI Effectiveness of Negative Pressure Wound Therapy During Aeromedical
   Evacuation Following Soft Tissue Injury and Infection
SO MILITARY MEDICINE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; BACTERIAL-COLONIZATION; IRRIGATION; CASUALTIES;
   BIOBURDEN; SALINE; LOAD; CARE
AB Introduction Negative pressure wound therapy (NPWT) is utilized early after soft tissue injury to promote tissue granulation and wound contraction. Early post-injury transfers via aeromedical evacuation (AE) to definitive care centers may actually induce wound bacterial proliferation. However, the effectiveness of NPWT or instillation NPWT in limiting bacterial proliferation during post-injury AE has not been studied. We hypothesized that instillation NPWT during simulated AE would decrease bacterial colonization within simple and complex soft tissue wounds. Methods The porcine models were anesthetized before any experiments. For the simple tissue wound model, two 4-cm dorsal wounds were created in 34.90.6kg pigs and were inoculated with Acinetobacter baumannii (AB) or Staphylococcus aureus 24hours before a 4-hour simulated AE or ground control. During AE, animals were randomized to one of the five groups: wet-to-dry (WTD) dressing, NPWT, instillation NPWT with normal saline (NS-NPWT), instillation NPWT with Normosol-R (R) (NM-NPWT), and RX-4-NPWT with the RX-4 system. For the complex musculoskeletal wound, hind-limb wounds in the skin, subcutaneous tissue, peroneus tertius muscle, and tibia were created and inoculated with AB 24hours before simulated AE with WTD or RX-4-NPWT dressings. Blood samples were collected at baseline, pre-flight, and 72hours post-flight for inflammatory cytokines interleukin (IL)-1 beta, IL-6, IL-8 and tumor necrosis factor alpha. Wound biopsies were obtained at 24hours and 72hours post-flight, and the bacteria were quantified. Vital signs were measured continuously during simulated AE and at each wound reassessment. Results No significant differences in hemodynamics or serum cytokines were noted between ground or simulated flight groups or over time in either wound model. Simulated AE alone did not affect bacterial proliferation compared to ground controls. The simple tissue wound arm demonstrated a significant decrease in Staphylococcus aureus and AB colony-forming units at 72hours after simulated AE using RX-4-NPWT. NS-NPWT during AE more effectively prevented bacterial proliferation than the WTD dressing. There was no difference in colony-forming units among the various treatment groups at the ground level. Conclusion The hypoxic, hypobaric environment of AE did not independently affect the bacterial growth after simple tissue wound or complex musculoskeletal wound. RX-4-NPWT provided the most effective bacterial reduction following simulated AE, followed by NS-NPWT. Future research will be necessary to determine ideal instillation fluids, negative pressure settings, and dressing change frequency before and during AE.
C1 [Baucom, Matthew R.; Wallen, Taylor E.; Youngs, Jaclyn; Singer, Kathleen E.; Delman, Aaron M.; Schuster, Rebecca M.; Blakeman, Thomas C.; Pritts, Timothy A.; Goodman, Michael D.] Univ Cincinnati, Dept Surg, Cincinnati, OH 45267 USA.
   [Strilka, Richard] Univ Cincinnati, US Air Force Sch Aerosp Med, Route Care Training Dept, Cincinnati, OH 45267 USA.
C3 University System of Ohio; University of Cincinnati; University System
   of Ohio; University of Cincinnati; U.S. Air Force School of Aerospace
   Medicine
RP Baucom, MR (通讯作者)，Univ Cincinnati, Dept Surg, Cincinnati, OH 45267 USA.
RI ; Wallen, Taylor/QMS-0406-2026
OI Goodman, Michael/0000-0001-7218-4855; Strilka,
   Richard/0000-0003-2707-7991; 
FU DoD [USAF FA8650-20-2-6G36]; NIH-Ruth Kirschstein T32 training grant
   [5T32GM008478-29]; National Institute of General Medical Sciences
   [T32GM008478] Funding Source: NIH RePORTER
FX This study was supported by the DoD grant (No. USAF FA8650-20-2-6G36)
   and NIH-Ruth Kirschstein T32 training grant (No. 5T32GM008478-29).
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NR 36
TC 3
Z9 5
U1 0
U2 3
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0026-4075
EI 1930-613X
J9 MIL MED
JI Milit. Med.
PD NOV 8
PY 2023
VL 188
SU _6
BP 295
EP 303
DI 10.1093/milmed/usad113
EA NOV 2023
PG 9
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA EZ5M9
UT WOS:001142773700039
PM 37948243
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Fang, R
   Dorlac, WC
   Flaherty, SF
   Tuman, C
   Cain, SM
   Popey, TLC
   Villard, DR
   Aydelotte, JD
   Dunne, JR
   Anderson, AM
   Powell, ET
AF Fang, Raymond
   Dorlac, Warren C.
   Flaherty, Stephen F.
   Tuman, Caroline
   Cain, Steven M.
   Popey, Tracy L. C.
   Villard, Douglas R.
   Aydelotte, Jayson D.
   Dunne, James R.
   Anderson, Adam M.
   Powell, Elisha T.
TI Feasibility of Negative Pressure Wound Therapy During Intercontinental
   Aeromedical Evacuation of Combat Casualties
SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
LA English
DT Article
DE Soft-tissue wounds; Aeromedical evacuation; Negative pressure; Military
   medicine; War; Wounds and injuries
ID VACUUM-ASSISTED CLOSURE; SOFT-TISSUE INJURIES; EXPERIENCE; MANAGEMENT
AB Objective: The objective of this study was to assess the feasibility of utilizing negative pressure wound therapy (NPWT) for the treatment of wartime soft-tissue wounds during intercontinental aeromedical evacuation.
   Background: Attempts to use NPWT during early phases of overseas contingency operations resulted in occasional vacuum system failures and potentially contributed to wound complications. These anecdotal episodes led to a perception that NPWT during aeromedical evacuation carried a high risk of wound complications and limited its use. As a result, NPWT was not frequently applied in the management of soft-tissue wounds before US casualty arrival in the continental United States (CONUS) for wounds sustained in the combat theaters. Concurrently, early NPWT on the traumatic wounds of host nation casualties not requiring aeromedical evacuation seemed to provide many benefits typically associated with the therapy such as decreased infection rates, earlier wound closure, and improved pain management.
   Methods: On a daily basis, study investigators reviewed the trauma inpatient census at Landstuhl Regional Medical Center, Germany, to identify patient candidates with soft-tissue extremity or torso wounds that required packing. Patient demographics, injuries, and previous wound treatments were recorded. Surgeons inspected wounds in the operating room and applied a NPWT dressing if deemed appropriate. NPWT was continued throughout the remainder of the patient's hospitalization and also during aeromedical evacuation to CONUS. A study investigator escorted the patient during aeromedical evacuation to educate the flight crews, to record the impact on crew workload, and to troubleshoot the system if necessary.
   Results: Thirty enrolled patients with 41 separate wounds flew from Germany to CONUS with a portable NPWT system (VAC Freedom System; Kinetic Concepts Incorporated, San Antonio, TX). All 30 patients arrived at the destination facilities with intact and functional systems. No significant in-flight complications were identified, impact on flight crew workload was negligible, and subjective feedback from both flight crews and patients was uniformly positive. For 29 patients, the NPWT dressing was replaced (frequently with serial exchanges) during initial surgical treatment in CONUS; the 30th patient underwent delayed primary closure of his right forearm fasciotomy. Receiving care teams reported no complications attributable to NPWT during aeromedical vacuation.
   Conclusions: NPWT is feasible during intercontinental aeromedical evacuation of combat casualties without an increase in wound complications or a significant impact on air crew workload. Further studies are indicated to evaluate the efficacy of NPWT in combat wounds compared with other wound care techniques.
C1 [Fang, Raymond; Tuman, Caroline; Cain, Steven M.; Popey, Tracy L. C.; Villard, Douglas R.] Landstuhl Reg Med Ctr, Landstuhl, Germany.
   [Dorlac, Warren C.] Univ Cincinnati, Cincinnati, OH USA.
   [Flaherty, Stephen F.; Aydelotte, Jayson D.] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
   [Dunne, James R.] Natl Naval Med Ctr, Bethesda, MD USA.
   [Powell, Elisha T.] Alaska Reg Hosp, Anchorage, AK USA.
C3 Landstuhl Regional Medical Center; University System of Ohio; University
   of Cincinnati; United States Department of Defense; United States Army;
   Walter Reed National Military Medical Center; Walter Reed National
   Military Medical Center
RP Fang, R (通讯作者)，LRMC Trauma Program, CMR 402, APO, AE 09180 USA.
EM Raymond.Fang@amedd.army.mil
CR [Anonymous], 2004, WOUNDS, p3S
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NR 21
TC 34
Z9 37
U1 0
U2 11
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0022-5282
EI 1529-8809
J9 J TRAUMA
JI J. Trauma-Injury Infect. Crit. Care
PD JUL
PY 2010
VL 69
SU 1
BP S140
EP S145
DI 10.1097/TA.0b013e3181e452a2
PG 6
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Surgery
GA 627AC
UT WOS:000280009000021
PM 20622609
DA 2026-07-24
ER

PT J
AU Zhang, N
   Liu, YB
   Yan, WQ
   Liu, F
AF Zhang, Ning
   Liu, Yibin
   Yan, Weiqi
   Liu, Fei
TI 被撤回的出版物: The effect of negative pressure wound therapy on the outcome of
   diabetic foot ulcers: A meta-analysis (Retracted article. See vol. 21,
   2024)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article; Retracted Publication
DE amputation; diabetic foot ulcer; wound healing
ID VACUUM-ASSISTED CLOSURE; MULTICENTER; MANAGEMENT
AB Negative pressure injury is one of the auxiliary methods of treating diabetes foot ulcers. It has been shown to be superior to conventional techniques in randomized controlled trials (RCTs). Nevertheless, the results of observational research are still scarce. A systematic review of RCTs and observations was carried out to evaluate the effectiveness and security of negative pressure wound therapy (NPWT) treatment for diabetes foot ulcers. Three English e-databases have been found for NPWT research. The meta-analyses of the comparative studies provided point estimates of results. Intermediate results were given as median and binary values were given in the form of odds ratios (OR). Seventeen trials, 13 RCTs and four randomized, controlled trials were found in the survey. Of these, 831 were treated with NPWT, 834 were treated with standard therapy. A total of 14 studies have been conducted to investigate the influence of NPWT on the healing of diabetic foot ulcers(DFU). In the study, NPWT was shown to speed up the healing of the wound in DFU patients(OR, 2.57; 95% CI, 1.72, 3.85 p < 0.0001). A subgroup analysis showed that NPWT was associated with an acceleration of the wound healing rate in 10 RCT trials (OR, 2.48; 95% CI, 1.58, 3.89 p < 0.001). In the four nRCT trials, NPWT was also shown to speed up the healing of the wound(OR, 2.95; 95% CI, 1.03, 8.42 p = 0.04). In 11 studies, the influence of NPWT on amputations of diabetes mellitus (DM) foot ulcers was investigated. The results showed that NPWT was associated with a reduction in amputations (OR, 0.53; 95% CI, 0.37, 0.74 p = 0.0002).In a subgroup of RCT trials, nine RCT trials showed a reduction in amputations(OR, 0.61; 95% CI, 0.43, 0.87 p = 0.007). In both nRCT trials, NPWT also showed a reduction in amputations (OR, 0.03; 95% CI, 0.00, 0.24 p = 0.001). Generally speaking, NPWT can help to heal the wound and lower the risk of amputations in people with diabetes. The subgroup analysis showed similar results for the RCT and non-RCT trials. NPWT can be used to treat diabetes foot ulcers caused by diabetes.
C1 [Zhang, Ning; Liu, Yibin; Yan, Weiqi; Liu, Fei] Ningxia Med Univ, Gen Hosp, Dept Emergency Hand & Foot Microsurg, 895 Shengli South St, Xingqing Dist 750004, Yinchuan, Peoples R China.
C3 Ningxia Medical University
RP Liu, F (通讯作者)，Ningxia Med Univ, Gen Hosp, Dept Emergency Hand & Foot Microsurg, 895 Shengli South St, Xingqing Dist 750004, Yinchuan, Peoples R China.
EM nydz6745890@163.com
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NR 36
TC 11
Z9 13
U1 2
U2 10
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2024
VL 21
IS 4
AR e14886
DI 10.1111/iwj.14886
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA I7835
UT WOS:001626893000001
PM 38651532
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Katsaros, I
   Papadakos, SP
   Despotidis, M
   Koutsoumpas, A
   Schizas, D
AF Katsaros, Ioannis
   Papadakos, Stavros P.
   Despotidis, Markos
   Koutsoumpas, Andreas
   Schizas, Dimitrios
TI Endoscopic vacuum-assisted closure as a first-line treatment for
   post-esophagectomy anastomotic leaks: A paradigm shift in management
SO WORLD JOURNAL OF GASTROINTESTINAL SURGERY
LA English
DT Review
DE Esophageal cancer; Esophagectomy; Anastomotic leak; Endoscopic
   vacuum-assisted closure; Endoscopic vacuum therapy
ID THERAPY; LEAKAGES; STENT; LIFE
AB Post-esophagectomy anastomotic leak (AL) is a severe complication following esophagectomy, contributing to increased morbidity, prolonged hospitalization, and a significant risk of mortality. Endoscopic vacuum-assisted closure (EndoVac) has emerged as a promising first-line treatment, offering a highly effective approach for managing post-esophagectomy AL. EndoVac therapy utilizes continuous negative pressure within the esophageal lumen or mediastinal cavity, promoting granulation tissue formation, accelerating wound healing, and enhancing AL closure rates. Compared to stenting, EndoVac provides distinct advantages, including superior adaptability to varying leak sizes and locations, enhanced secretion drainage, and lower rates of reintervention. Clinical studies have demonstrated higher success rates, decreased post-intervention complications, and shorter hospital stays. Despite its advantages, challenges persist in patient selection, procedural expertise, and accessibility. EndoVac application requires experienced endoscopic teams and multidisciplinary expertise, which is best achieved in high-volume centers with specialized care. Variability in EndoVac protocols necessitate further refinement and standardization to optimize treatment outcomes. The integration of EndoVac into standardized treatment guidelines holds promise for improving patient outcomes and redefining the management approach for this challenging postoperative complication.
C1 [Katsaros, Ioannis; Despotidis, Markos; Schizas, Dimitrios] Natl & Kapodistrian Univ Athens, Dept Surg 1, Agiou Thoma 17, Athens 11527, Attiki, Greece.
   [Papadakos, Stavros P.; Koutsoumpas, Andreas] Natl & Kapodistrian Univ Athens, Dept Gastroenterol 1, Athens 11527, Greece.
C3 National & Kapodistrian University of Athens; National & Kapodistrian
   University of Athens
RP Katsaros, I; Schizas, D (通讯作者)，Natl & Kapodistrian Univ Athens, Dept Surg 1, Agiou Thoma 17, Athens 11527, Attiki, Greece.
EM gikats.md@gmail.com
RI Katsaros, Ioannis/AHI-2537-2022; SCHIZAS, DIMITRIOS/Z-3323-2019;
   Papadakos, Stavros/AFF-9357-2022
OI Papadakos, Stavros/0000-0003-1583-1125
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   Sivarajan S, 2024, ANN ESOPHAGUS, V7, DOI 10.21037/aoe-23-24
   Sundaram S, 2025, SURG ENDOSC, V39, P4857, DOI 10.1007/s00464-025-11899-8
   Triantafyllou A, 2025, J CLIN MED, V14, DOI 10.3390/jcm14113694
   Ubels S, 2023, BJS-BRIT J SURG, V110, P852, DOI 10.1093/bjs/znad123
   Vetter D, 2020, LANGENBECK ARCH SURG, V405, P1069, DOI 10.1007/s00423-020-01926-8
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NR 42
TC 0
Z9 0
U1 0
U2 0
PU BAISHIDENG PUBLISHING GROUP INC
PI PLEASANTON
PA 7041 Koll Center Parkway, Suite 160, PLEASANTON, CA, UNITED STATES
SN 1948-9366
J9 WORLD J GASTRO SURG
JI World J. Gastrointest. Surg.
PD DEC 27
PY 2025
VL 17
IS 12
AR 113305
DI 10.4240/wjgs.v17.i12.113305
PG 7
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA AM3LB
UT WOS:001651521900017
PM 41479695
OA Green Accepted, gold
DA 2026-07-24
ER

PT J
AU Siegel, HJ
   Long, JL
   Watson, KM
   Fiveash, JB
AF Siegel, Herrick J.
   Long, James L.
   Watson, Kevin M.
   Fiveash, John B.
TI Vacuum-assisted closure for radiation-associated wound complications
SO JOURNAL OF SURGICAL ONCOLOGY
LA English
DT Article
DE vacuum assisted closure; wound complication; radiation necrosis; wound
   management; soft tissue sarcoma
ID SOFT-TISSUE SARCOMA; THERAPY; RADIOTHERAPY; BRACHYTHERAPY; EXTREMITY;
   RESECTION
AB Background and Objectives: Vacuum-assisted closure (VAC) technology has proven to be effective in the management of soft tissue loss from infections, vascular insufficiency, and traumatic disorders and may have a similar benefit in the musculoskeletal oncology patient. This study reports a single institution's experience with VAC technology in the management of radiation-associated wound complications in patients with soft tissue sarcomas.
   Materials: Twenty-two patients treated with both surgical intervention and radiation therapy developed either superficial or deep wound complications that were managed with the VAC device. This study group was compared to a retrospectively identified comparison group of 19 patients, in which the VAC device was not used.
   Results: Hospital stay (P < 0.025), length of overall treatment (P < 0.025), number of operative debridements (P < 0.05) and success of wound closure without the need for soft tissue transposition (P < 0.01) was found to be significantly less in the study groups as compared to those not treated with the VAC device.
   Conclusion: VAC technology appears to be safe and effective in the treatment of radiation-associated wound complications.
C1 Univ Alabama Birmingham, Dept Surg, Div Orthopaed Surg, Birmingham, AL USA.
   Univ Alabama Birmingham, Dept Surg, Div Plast Surg, Birmingham, AL USA.
   Univ Alabama Birmingham, Dept Radiat Oncol, Birmingham, AL USA.
C3 University of Alabama System; University of Alabama Birmingham;
   University of Alabama System; University of Alabama Birmingham;
   University of Alabama System; University of Alabama Birmingham
RP Siegel, HJ (通讯作者)，FOT 920, 1530 3rd Ave S, Birmingham, AL 35294 USA.
EM herrick.siegel@ortho.uab.edu
CR ARBEIT JM, 1987, J CLIN ONCOL, V5, P480, DOI 10.1200/JCO.1987.5.3.480
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NR 21
TC 29
Z9 33
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0022-4790
EI 1096-9098
J9 J SURG ONCOL
JI J. Surg. Oncol.
PD DEC 1
PY 2007
VL 96
IS 7
BP 575
EP 582
DI 10.1002/jso.20846
PG 8
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA 238UL
UT WOS:000251473100009
PM 17999398
DA 2026-07-24
ER

PT J
AU Tian, B
   Khoo, D
   Tay, AC
   Soo, KC
   Tan, NC
   Tan, HK
   Iyer, NG
AF Tian, Brian
   Khoo, Deborah
   Tay, Ai Choo
   Soo, Khee-Chee
   Tan, Ngian Chye
   Tan, Hiang Khoon
   Iyer, N. Gopalakrishna
TI Management of orocutaneous fistulas using a vacuum-assisted closure
   system
SO HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND
   NECK
LA English
DT Article
DE salivary fistula; pharyngocutaneous fistula; anastomotic leak;
   postoperative complications; vacuum-assisted closure
ID PHARYNGOCUTANEOUS FISTULA; WOUND CONTROL; NECK WOUNDS; THERAPY; SOFT;
   STABILITY; STRESS; HEAD
AB BackgroundThe vacuum-assisted closure (VAC) system has been used to manage complicated wounds. The purpose of this study was to describe a novel technique in using the VAC system for orocutaneous fistulas.
   MethodsA retrospective study was performed on 10 patients treated at the National Cancer Centre, Singapore, who developed postoperative orocutaneous fistulas. Hydrogum dental paste was used as a sealant together with the VAC system to close the fistulas. We used either the RENASYS or VAC ATS system with 50 mm Hg to 125 mm Hg continuous suction.
   ResultsThe 10 patients developed 11 fistulas. The median age of this cohort was 67 years (range, 33-80 years). Nine patients had successful closure of their fistulas with VAC therapy whereas 1 patient had unsuccessful VAC therapy and required flap reconstruction. The median time to fistula closure was 19 days (range, 6-36 days). The median time to radiotherapy after surgery was 46 days (range, 26-62 days).
   ConclusionVAC therapy is an effective treatment option for orocutaneous fistulas. (c) 2013 Wiley Periodicals, Inc. Head Neck 36: 873-881, 2014
C1 [Tian, Brian; Khoo, Deborah; Soo, Khee-Chee; Tan, Ngian Chye; Tan, Hiang Khoon; Iyer, N. Gopalakrishna] Natl Canc Ctr Singapore, Dept Surg Oncol, Singapore 169610, Singapore.
   [Tay, Ai Choo] Singapore Gen Hosp, Dept Nursing, Singapore, Singapore.
C3 National Cancer Centre Singapore (NCCS); Singapore General Hospital
RP Iyer, NG (通讯作者)，Natl Canc Ctr Singapore, 11 Hosp Dr, Singapore 169610, Singapore.
EM gopaliyer@yahoo.com
RI Tan, Hiang Khoon/AAG-2815-2021
OI Tan, Hiang Khoon/0000-0002-8565-2926; Iyer, N.
   Gopalakrishna/0000-0002-8812-6219; Khoo, Deborah/0000-0001-7961-5339
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NR 22
TC 25
Z9 28
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1043-3074
EI 1097-0347
J9 HEAD NECK-J SCI SPEC
JI Head Neck-J. Sci. Spec. Head Neck
PD JUN
PY 2014
VL 36
IS 6
BP 873
EP 881
DI 10.1002/hed.23393
PG 9
WC Otorhinolaryngology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology; Surgery
GA AH9VP
UT WOS:000336493200021
PM 23733717
DA 2026-07-24
ER

PT J
AU ElSayed, NA
   Aleppo, G
   Aroda, VR
   Bannuru, RR
   Brown, FM
   Bruemmer, D
   Collins, BS
   Gibbons, CH
   Giurini, JM
   Hilliard, ME
   Isaacs, D
   Johnson, EL
   Kahan, S
   Khunti, K
   Leon, J
   Lyons, SK
   Perry, ML
   Prahalad, P
   Pratley, RE
   Seley, JJ
   Stanton, RC
   Sun, JK
   Gabbay, RA
AF ElSayed, Nuha A.
   Aleppo, Grazia
   Aroda, Vanita R.
   Bannuru, Raveendhara R.
   Brown, Florence M.
   Bruemmer, Dennis
   Collins, Billy S.
   Gibbons, Christopher H.
   Giurini, John M.
   Hilliard, Marisa E.
   Isaacs, Diana
   Johnson, Eric L.
   Kahan, Scott
   Khunti, Kamlesh
   Leon, Jose
   Lyons, Sarah K.
   Perry, Mary Lou
   Prahalad, Priya
   Pratley, Richard E.
   Seley, Jane Jeffrie
   Stanton, Robert C.
   Sun, Jennifer K.
   Gabbay, Robert A.
CA American Diabet Assoc
TI Retinopathy, Neuropathy, and Foot Care: Standards of Care in
   Diabetes-2023
SO DIABETES CARE
LA English
DT Article
ID DIABETIC PERIPHERAL NEUROPATHY; CONTROL-CARDIOVASCULAR-RISK; INTENSIVE
   INSULIN THERAPY; HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED CLOSURE;
   COMPLICATIONS TRIAL/EPIDEMIOLOGY; DOUBLE-BLIND; PANRETINAL
   PHOTOCOAGULATION; ORTHOSTATIC HYPOTENSION; POSITION STATEMENT
RI Lyons, Sarah/AGO-9717-2022; ElSayed, Nuha/KMA-0245-2024; Bannuru,
   Raveendhara/G-2601-2011; /GQB-2573-2022; Sun, Jennifer/AAP-2734-2020;
   Gabbay, Robert/KLC-9779-2024; Giurini, John/LZH-7752-2025; Isaacs,
   Diana/AAE-6709-2021; Phoon, Richard/AGI-5082-2022
OI Lyons, Sarah/0000-0002-3686-0112; ElSayed, Nuha/0000-0003-1217-4916;
   Hilliard, Marisa/0000-0002-8813-629X; Bannuru,
   Raveendhara/0000-0002-8069-5783; 
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NR 107
TC 128
Z9 159
U1 2
U2 33
PU AMER DIABETES ASSOC
PI ALEXANDRIA
PA 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA
SN 0149-5992
EI 1935-5548
J9 DIABETES CARE
JI Diabetes Care
PD JAN
PY 2023
VL 46
SU 1
BP S203
EP S215
DI 10.2337/dc23-S012
PG 13
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA 7K3SJ
UT WOS:000905206200014
PM 36507636
OA Green Submitted, Bronze
HC Y
HP N
DA 2026-07-24
ER

PT J
AU Santarpino, G
   Gazdag, L
   Sirch, J
   Vogt, F
   Ledwon, M
   Fischlein, T
   Pfeiffer, S
AF Santarpino, Giuseppe
   Gazdag, Lazlo
   Sirch, Joachim
   Vogt, Ferdinand
   Ledwon, Miroslaw
   Fischlein, Theodor
   Pfeiffer, Steffen
TI A Retrospective Study to Evaluate Use of Negative Pressure Wound Therapy
   in Patients Undergoing Bilateral Internal Thoracic Artery Grafting
SO OSTOMY WOUND MANAGEMENT
LA English
DT Article
DE retrospective study; postoperative complications; surgical wound
   infection; anastomosis internal mammary-coronary artery
ID INCISION MANAGEMENT-SYSTEM; VACUUM-ASSISTED CLOSURE; CARDIAC-SURGERY;
   PREVENTION; EXPERIENCE; INFECTION
AB Bilateral internal thoracic artery (BITA) grafting may be associated with a higher risk of postoperative deep sternal wound infection than monolateral internal thoracic artery grafting due to a limited blood supply to the thoracic chest wall. Because preliminary studies suggest negative pressure wound therapy (NPWT) may reduce the risk of infection, a retrospective chart review of 129 patients who underwent BITA between February 2003 and October 2014 was conducted. Of those, 21 patients received NPWT for 5 days immediately following surgery and the incisions of 108 patients were covered with a conventional gauze dressing. Patient demographic and history variables as well as surgical procedure and outcome variables were abstracted. Outcome variables assessed included infection, need for transfusion, and length of hospital stay. The NPWT group was significantly younger (average age 55.9 +/- 7.6 versus 60 +/- 10.5 years, P = 0.049), had fewer urgent/emergent surgeries (4 [19%] versus 36 [33.3%], P = 0.247), and had significantly lower surgical risk scores (2.0 +/- 2.3 versus 3.8 +/- 2.8, P = 0.010). The rate of deep sternal wound infections was lower in the NPWT than in the control group, but the difference was not statistically significant (0% versus 5.6%, P = 0.336). Sternal instability was noted in 4 control patients, requiring wound re-exploration versus 0 in the NPWT group (3.7% versus 0%, P = 0.487). One (1) patient in the NPWT group had postoperative bleeding that required removal of the device. The rates of re-thoracotomy due to bleeding were 9.3% in the control compared to 4.8% in the NPWT group (P = 0.435), which translated into a greater need for blood transfusions (1.77 +/- 3.4 units versus 0.3 3 +/- 0.7 units, P = 0.056) and larger chest drainage volume (997.8 +/- 710 mL versus 591.2 +/- 346 mL, P = 0.012) in the control group. Hospital stay was longer in the control group, but the difference was not statistically significant (12 +/- 8.8 days versus 9.4 +/- 4.2 days, P = 0.184). These preliminary results are encouraging, and prospective, randomized, controlled clinical studies to compare the efficacy, effectiveness, and cost-effectiveness of NPWT to other wound management modalities following cardiac surgery are warranted.
C1 [Santarpino, Giuseppe; Fischlein, Theodor; Pfeiffer, Steffen] Paracelsus Med Univ, Klinikum Nurnberg, Dept Cardiac Surg, Cardiovasc Ctr,Cardiac Surg, Nurnberg, Germany.
   [Santarpino, Giuseppe; Gazdag, Lazlo; Sirch, Joachim; Vogt, Ferdinand; Ledwon, Miroslaw] Paracelsus Med Univ, Klinikum Nurnberg, Dept Cardiac Surg, Cardiovasc Ctr, Breslauer Str 201, D-90471 Nurnberg, Germany.
C3 Klinikum Nurnberg; Klinikum Nurnberg
RP Santarpino, G (通讯作者)，Paracelsus Med Univ, Klinikum Nurnberg, Dept Cardiac Surg, Cardiovasc Ctr, Breslauer Str 201, D-90471 Nurnberg, Germany.
EM giuseppe.santarpino@klinikum-nuernberg.de
RI Vogt, Ferdinand/AAN-4881-2021; Santarpino, Giuseppe/H-8678-2013
OI Vogt, Ferdinand/0000-0002-1924-6823; Santarpino,
   Giuseppe/0000-0002-4913-9834
CR Atkins BZ, 2011, INT WOUND J, V8, P56, DOI 10.1111/j.1742-481X.2010.00743.x
   Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Berdajs D, 2006, ANN THORAC SURG, V81, P2155, DOI 10.1016/j.athoracsur.2006.01.020
   Colli A, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-160
   ElBardissi AW, 2012, J THORAC CARDIOV SUR, V143, P273, DOI 10.1016/j.jtcvs.2011.10.029
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   Ingargiola Michael J, 2013, Eplasty, V13, pe49
   Masden D, 2012, ANN SURG, V255, P1043, DOI 10.1097/SLA.0b013e3182501bae
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
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   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
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   Wu YC, 2015, J DIABETES
   Zhou Z. H., 2010, Journal of Medical Engineering & Technology, V34, P285, DOI 10.3109/03091901003753041
NR 15
TC 12
Z9 12
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 0889-5899
EI 1943-2720
J9 OSTOMY WOUND MANAG
JI Ostomy Wound Manag.
PD DEC
PY 2015
VL 61
IS 12
BP 26
EP 30
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DD9JB
UT WOS:000370240400005
PM 27763880
DA 2026-07-24
ER

PT J
AU Madrigal, P
   Moshal, T
   Bernabe, R
   Yenikomshian, H
   Gillenwater, J
AF Madrigal, Paloma
   Moshal, Tayla
   Bernabe, Rendell
   Yenikomshian, Haig
   Gillenwater, Justin
TI A comparison of negative pressure wound therapy modalities, VAC versus
   non-commercial NPWT alternatives: A systematic review of RCTs/CCTs
SO JOURNAL OF TISSUE VIABILITY
LA English
DT Review
ID ASSISTED CLOSURE; SKIN-GRAFTS
AB Background: Negative pressure wound therapy (NPWT) has been described as an effective treatment for wounds of various etiologies, however it is expensive. Various authors have investigated low-cost alternatives to commercial NPWT devices. A systematic review summarizing their findings is needed for clinicians operating in resource-limited locations and for those interested in potential cost savings.Methods: A systematic review was performed evaluating articles from Cochrane, PubMed and EMBASE. The studies included randomized controlled trials (RCTs) and controlled clinical trials (CCTs) that compared commercially available Vacuum-Assisted Closure (VAC) devices with non-commercial NPWT modalities in human subjects. Results: Seven hundred and ninety-six articles were retrieved, of which six met inclusion criteria. All six studies were RCTs and had in total 409 participants with wounds of various etiologies, including acute, chronic, and traumatic wounds. All studies compared VAC to a non-commercial NPWT device. Five studies were found to have low risk of bias, and one study had high risk of bias. There were three types of non-commercial NPWT devices used: wall suction applied to a sealed gauze dressing (GSUC), AquaVac, and Redon drains. The following outcomes were assessed: granulation tissue formation, effect on wound size area, skin graft take, pain/ time associated with dressing changes and cost. In trials that compared GSUC vs VAC, there was no significant difference between the two groups for the following outcomes: granulation tissue formation, effect on wound size and skin graft take. GSUC dressings were significantly less painful and less time-consuming than VAC dressings. In the trial that compared AquaVac vs VAC, there was no significant difference between the two groups for the following outcomes: granulation tissue formation, effect on wound size, and the time or pain associated with dressing changes. In the trial that compared Redon drains vs VAC, there was significantly more granulation tissue formed in the VAC group. All non-commercial NPWT devices were found to be less costly than VAC.Conclusion: The data from the trials evaluated in this review indicate that GSUC and AquaVac are two non-commercial NPWT devices that are non-inferior to VAC for various outcomes while also being less costly. GSUC was less painful and less time-consuming than VAC. Of the non-commercial NPWT devices evaluated in this review, GSUC had the most evidence to support its future use. Prospective, multi-institutional RCTs with a large sample size are needed to confirm the findings presented here.
C1 [Madrigal, Paloma; Moshal, Tayla] Univ Southern Calif, Keck Sch Med, Los Angeles, CA USA.
   [Bernabe, Rendell] Rutgers Robert Wood Johnson Med Sch, New Brunswick, NJ USA.
   [Yenikomshian, Haig; Gillenwater, Justin] Univ Southern Calif, Div Plast & Reconstruct Surg, Keck Sch Med, Los Angeles, CA 90033 USA.
C3 University of Southern California; Rutgers University System; Rutgers
   University New Brunswick; Rutgers University Biomedical & Health
   Sciences; University of Southern California
RP Gillenwater, J (通讯作者)，Univ Southern Calif, Div Plast & Reconstruct Surg, Keck Sch Med, Los Angeles, CA 90033 USA.
EM Justin.Gillenwater@med.usc.edu
OI Maigal, Paloma/0000-0002-2646-1708; Bernabe,
   Rendell/0000-0002-4574-8640; Moshal, Tayla/0000-0002-9078-7809; BERNABE,
   RENDELL/0009-0007-5334-691X; Gillenwater, Justin/0000-0001-9410-6030
CR Anesäter E, 2011, INT WOUND J, V8, P336, DOI 10.1111/j.1742-481X.2011.00790.x
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   Bui TD, 2006, AM J SURG, V192, P235, DOI 10.1016/j.amjsurg.2006.01.013
   Cocjin HGB, 2019, J BONE JOINT SURG AM, V101, P1990, DOI 10.2106/JBJS.19.00125
   Cuomo Roberto, 2017, Acta Biomed, V88, P297, DOI 10.23750/abm.v88i3.5737
   Dorafshar AH, 2012, ANN PLAS SURG, V69, P79, DOI 10.1097/SAP.0b013e318221286c
   Fraccalvieri M, 2014, INT WOUND J, V11, P164, DOI 10.1111/j.1742-481X.2012.01058.x
   Fraccalvieri M, 2011, INT WOUND J, V8, P492, DOI 10.1111/j.1742-481X.2011.00821.x
   Harris TG, 2019, J BONE JOINT SURG AM, V101, DOI 10.2106/JBJS.19.01015
   Hudson DA, 2015, INT WOUND J, V12, P195, DOI 10.1111/iwj.12080
   Jeffery SL, ADV WOUND THERAPIES
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   Kim JJ, 2017, PRS-GLOB OPEN, V5, DOI 10.1097/GOX.0000000000001211
   Kirsner RS, 2020, WOUNDS, V32, P328
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   Peinemann F, 2019, J EVID-BASED MED, V12, P125, DOI 10.1111/jebm.12324
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   Sposato G, 2001, BRIT J PLAST SURG, V54, P235, DOI 10.1054/bjps.2000.3537
   Sterne JAC, 2019, BMJ-BRIT MED J, V366, DOI 10.1136/bmj.l4898
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   Ye J, 2015, MED BALTIM, V94, P426
NR 28
TC 8
Z9 13
U1 0
U2 4
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0965-206X
EI 1876-4746
J9 J TISSUE VIABILITY
JI J. Viab.
PD NOV
PY 2022
VL 31
IS 4
BP 630
EP 636
DI 10.1016/j.jtv.2022.10.002
PG 7
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA 7N2KA
UT WOS:000907172100001
PM 36289040
DA 2026-07-24
ER

PT J
AU Wedemeyer, J
   Schneider, A
   Manns, MP
   Jackobs, S
AF Wedemeyer, Jochen
   Schneider, Andrea
   Manns, Michael P.
   Jackobs, Steffan
TI Endoscopic vacuum-assisted closure of upper intestinal anastomotic leaks
SO GASTROINTESTINAL ENDOSCOPY
LA English
DT Article
ID ESOPHAGEAL; MANAGEMENT; SURGERY; STENTS; CARCINOMA
AB Background: Management of intrathoracic anastomotic leaks remains an interdisciplinary challenge. Established treatment options include percutaneous drainage, endoscopic closure, or even surgical revision. All these procedures are associated with high morbidity and mortality rates.
   Objective: We report a new, effective endoscopic treatment option for intrathoracic esophageal anastomotic leaks by using an endoscopic vacuum-assisted Closure system.
   Patients: Two patients with intrathoracic anastomotic leaks after esophagectomy and gastrectomy were included.
   Methods: Surgical reinterventions failed to seal the leaks in 1 patient, whereas in the other patient the anastomotic leakage persisted after endoscopic placement of 2 covered self-expanding metal stents. We endoscopically placed transnasal draining tubes that were armed with a size-adjusted sponge at their distal tip in the necrotic anastomotic cavities. Continuous suction was applied. Sponge and drain were changed twice a week.
   Results: No complications were noted during the course of treatment. After a median of 15 days, closure of the wound cavities was achieved in all cases. A median of 5 endoscopic interventions was necessary. Both patients returned gradually to a solid diet without recurrence of the leaks.
   Conclusion: Endoscopic vacuum-assisted closure might be an effective alternative in the treatment of upper intestinal anastomotic leaks.
C1 [Wedemeyer, Jochen; Schneider, Andrea; Manns, Michael P.] Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, D-30625 Hannover, Germany.
   [Jackobs, Steffan] Hannover Med Sch, Dept Gen Visceral & Transplantat Surg, D-30625 Hannover, Germany.
C3 Hannover Medical School; Hannover Medical School
RP Wedemeyer, J (通讯作者)，Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Carl Neuberg Str 1, D-30625 Hannover, Germany.
RI Manns, Michael/AFG-3063-2022
CR Faller J, 1996, SURG TODAY, V26, P368, DOI 10.1007/BF00311610
   Gelbmann CM, 2004, ENDOSCOPY, V36, P695, DOI 10.1055/s-2004-825656
   HOLLE G, 2007, UNFALLCHIRURG   0602
   Ikeguchi M, 2001, HEPATO-GASTROENTEROL, V48, P1517
   Kauer WKH, 2008, SURG ENDOSC, V22, P50, DOI 10.1007/s00464-007-9504-5
   Lang H, 2000, EUR J SURG ONCOL, V26, P168, DOI 10.1053/ejso.1999.0764
   Langer FB, 2005, ANN THORAC SURG, V79, P398, DOI 10.1016/j.athoracsur.2004.07.006
   Lee BI, 2006, GASTROINTEST ENDOSC, V64, P1024, DOI 10.1016/j.gie.2006.04.017
   LEE Y, 1994, SURG TODAY, V24, P24, DOI 10.1007/BF01676880
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NR 17
TC 149
Z9 176
U1 0
U2 7
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0016-5107
EI 1097-6779
J9 GASTROINTEST ENDOSC
JI Gastrointest. Endosc.
PD APR
PY 2008
VL 67
IS 4
BP 708
EP 711
DI 10.1016/j.gie.2007.10.064
PG 4
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA 282VW
UT WOS:000254596300022
PM 18374029
DA 2026-07-24
ER

PT J
AU Jungius, KP
   Chilla, BK
   Labler, L
   Teodorovic, N
   Marincek, B
AF Jungius, K. P.
   Chilla, B. K.
   Labler, L.
   Teodorovic, N.
   Marincek, B.
TI Non-invasive assessment of the perfusion of wounds using Power Doppler
   imaging:: Vacuum assisted Closure® versus direct wound closure
SO ULTRASCHALL IN DER MEDIZIN
LA German
DT Article
DE Power Doppler; vacuum-sealing; vacuum assisted closure; perfusion
ID MANAGEMENT; PHYSIOLOGY; ULTRASOUND; THERAPY
AB Aim: The goal of our study was to assess the perfusion in wounds treated by Vacuum assisted closure (VAC) compared to primary wound closure (R)
   Method: Power Doppler Ultrasound (PDUS) was carried out under standardised conditions in 15 VAC-treated and 10 primarily closed wounds as well as on altogether 25 intraindividual reference areas. All data were sent to a work station for post-processing to determine the perfused area. Statistical data analysis was performed with the Mann-Whitney test.
   Results: Both VAC((c))-treated wounds and primarily closed wounds showed a significant increase of the perfusion when compared to the intraindividual reference area (p < 0.0001). In VAC-treated wounds, a markedly increased perfusion was measured compared to the wounds closed primarily (p < 0.0001). Perfusion decreased during treatment, but in two VAC-treated wounds, an initial increase of the perfusion was observed. Both these wounds were grossly infected.
   Conclusion: PDUS allows the quantification of the differences in wound perfusion. This can be helpful in the detection of progressive local wound infections.
C1 Inst Diagnost Radiol, Zurich, Switzerland.
   Klin Widerherstellungschirurg, Zurich, Switzerland.
RP Jungius, KP (通讯作者)，Spitalzentrum Oberwallis, Dept Radiol, Uberlandstr 14, CH-3900 Brig, Switzerland.
EM karl.peter.jungius@rsv-gnw.ch
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Fleischmann W, 1996, UNFALLCHIRURG, V99, P283
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   Greiner L, 2005, ULTRASCHALL MED, V26, P183, DOI 10.1055/s-2005-858336
   Huber S, 2001, ULTRASOUND MED BIOL, V27, P3, DOI 10.1016/S0301-5629(00)00282-9
   HUNT TK, 1988, ANN EMERG MED, V17, P1265, DOI 10.1016/j.mpsur.2017.06.004
   Joseph E, 2000, WOUNDS, V12, P60
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   Jung EM, 2005, CLIN HEMORHEOL MICRO, V33, P63
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
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NR 18
TC 2
Z9 2
U1 0
U2 0
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0172-4614
EI 1438-8782
J9 ULTRASCHALL MED
JI Ultraschall Med.
PD OCT
PY 2006
VL 27
IS 5
BP 473
EP 477
DI 10.1055/s-2005-859001
PG 5
WC Acoustics; Radiology, Nuclear Medicine & Medical Imaging
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Acoustics; Radiology, Nuclear Medicine & Medical Imaging
GA 103XI
UT WOS:000241920100011
PM 16596505
DA 2026-07-24
ER

PT J
AU Verma, H
   Ktenidis, K
   George, RK
   Tripathi, R
AF Verma, Himanshu
   Ktenidis, Kiriakos
   George, Robbie K.
   Tripathi, Ramesh
TI Vacuum-assisted closure therapy for vascular graft infection (Szilagyi
   grade III) in the groin - a 10-year multi-center experience
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Graft preservation; Sartorious flap; Vacuum therapy; Vascular graft
   infections
ID MUSCLE-FLAP COVERAGE; CONSECUTIVE PATIENT SERIES; MANAGEMENT
AB The aim of the study was to evaluate the benefit of vacuum-assisted closure (VAC) therapy in the management of deep, alloplastic graft infections (Szilagyi grade III) in the groin. From 2000 to 2009, we identified and included in our study 72 deep inguinal infections in 68 patients, involving native as well as synthetic graft or patch material. There were 29 early graft infections (<30 days after implantation) and 43 late infections (30 days after implantation). Among these, 17 cases involved native grafts/patches (12 grafts and 5 patches), while 55 cases involved non-native grafts/patches [26 polytetrafluorethylene (PTFE) grafts and 24 Dacron grafts (Haemashield, Meadox Medical, Boston Scientific Corporation, Natick, NY; Gelsoft graft, Vascutek, Inchinnan, Renfrewshire, Scotland, UK; Intervascular, Mahwah, NJ); INVISTA, and 5 Vascu-Guard bovine pericardial patches; Synovis Surgical Innovation]. All patients were treated with multiple wound debridements, graft salvage, sartorius myoplasty, intravenous antibiotics and VAC therapy until thorough surface healing was achieved. Exclusion criteria were an alloplastic graft infection with proximal expansion above the inguinal ligament, blood culture positive for septicaemia or septic anastomotic herald or overt bleeding. Nine months after initiation of therapy, overall, graft/patch salvage was achieved in 61 of 72 (847%) cases. Of the native graft/patch group, infected graft material was replaced with an autogenous great saphenous vein graft or patch in four patients (235%). In the non-native group, vein or synthetic graft preservation without revision was achieved in 48 of 55 (873%) patients. The mean duration of VAC therapy was 16 +/- 77 days, and postoperative mean hospital stay was 253 +/- 85 days. In 23 of 72 (319%) cases, a secondary closure of the wound was achieved; in the other 49 cases, wound healing was achieved by meshed split-thickness skin grafting. Mean wound healing time for all wounds was 243 +/- 125 days. Specific complications during VAC therapy were wound fluid retention in 2 cases and an increased need for analgesics in 12 cases (1666%). Negative pressure wound therapy (NPWT) has been reported to be useful in the treatment of severe wound infections. Even in the presence of synthetic vascular graft material, NPWT can greatly simplify challenging wound-healing problems leading to wound dehiscence and its sequelae. Our long-term experience demonstrates the safety and effectiveness of VAC therapy in the management of deep graft infections.
C1 [Verma, Himanshu; George, Robbie K.; Tripathi, Ramesh] Narayana Hrudayalaya, Narayana Inst Vasc Sci, Bangalore 560099, Karnataka, India.
   [Ktenidis, Kiriakos] Aristotle Univ Thessaloniki, Papageorgiou Gen Hosp, Dept Vasc Surg, Surg Univ Clin 1, GR-54006 Thessaloniki, Greece.
C3 Aristotle University of Thessaloniki; Papageorgiou Hospital
RP Tripathi, R (通讯作者)，Narayana Hrudayalaya, Narayana Inst Vasc Sci, 258-A Bommasandra Ind Area,Hosur Rd, Bangalore 560099, Karnataka, India.
EM ramesh.tripathi@vascularsurgeon.org
RI Tripathi, Ramesh/C-2934-2017
OI Tripathi, Ramesh/0000-0001-7099-1733; George, Robbie/0000-0001-6981-3817
CR Adamkova M, 2005, Acta Chir Plast, V47, P24
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   Williams IM, 2003, EUR J VASC ENDOVASC, V25, P390, DOI 10.1053/ejvs.2002.1890
NR 20
TC 25
Z9 31
U1 1
U2 4
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2015
VL 12
IS 3
BP 317
EP 321
DI 10.1111/iwj.12110
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CI1CA
UT WOS:000354476800016
PM 23796163
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Kumar, S
   O'Donnell, ME
   Khan, K
   Dunne, G
   Carey, PD
   Lee, J
AF Kumar, Susim
   O'Donnell, Mark E.
   Khan, Khalid
   Dunne, Gillian
   Carey, P. Declan
   Lee, Jack
TI Successful treatment of perineal necrotising fasciitis and associated
   pubic bone osteomyelitis with the vacuum assisted closure system
SO WORLD JOURNAL OF SURGICAL ONCOLOGY
LA English
DT Article
AB Background: Acute necrotising fasciitis is a life-threatening condition, which requires urgent surgical intervention. Surgical debridement is invariably associated with large areas of tissue loss.
   Case presentation: We present a 58-year old woman with a past history of cervical carcinoma who presented with necrotising fasciitis of the perineum and upper thighs with associated pubic bone osteomyelitis. Following extensive debridement, a Vacuum Assisted Closure (VAC) system was applied to the large residual defect to facilitate skin graft application and optimise wound healing.
   Conclusion: This case demonstrates the successful management of a complex and potentially lethal wound of the perineum with debridement, skin grafting and the VAC system.
C1 [Kumar, Susim; O'Donnell, Mark E.; Khan, Khalid; Dunne, Gillian; Carey, P. Declan; Lee, Jack] Belfast City Hosp, Dept Gen Surg, Belfast BT9 7AB, Antrim, North Ireland.
C3 Belfast City Hospital
RP O'Donnell, ME (通讯作者)，Belfast City Hosp, Dept Gen Surg, Lisburn Rd, Belfast BT9 7AB, Antrim, North Ireland.
EM susimkumar@btinternet.com; modonnell904@hotmail.com;
   kalid.khan@belfasttrust.hscni.net; gillian.dunne@belfasttrust.hsci.net;
   declan.carey@belfasttrust.hscni.net; jacklee@doctors.net.uk
CR de Geus HRH, 2005, INTENS CARE MED, V31, P601, DOI 10.1007/s00134-004-2553-5
   Liu SYW, 2006, WORLD J GASTROENTERO, V12, P5256
   Phelps JR, 2006, OSTOMY WOUND MANAG, V52, P54
   Poromanski I, 2004, J Wound Care, V13, P307
   Schaffzin DM, 2004, DIS COLON RECTUM, V47, P1745, DOI 10.1007/s10350-004-0633-9
   Wong CH, 2003, J BONE JOINT SURG AM, V85A, P1454, DOI 10.2106/00004623-200308000-00005
   Young Michael H, 2005, Expert Rev Anti Infect Ther, V3, P279, DOI 10.1586/14787210.3.2.279
   Yuen JC, 2002, J CRANIOFAC SURG, V13, P762, DOI 10.1097/00001665-200211000-00009
NR 8
TC 14
Z9 17
U1 0
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1477-7819
J9 WORLD J SURG ONCOL
JI World J. Surg. Oncol.
PD JUN 24
PY 2008
VL 6
AR 67
DI 10.1186/1477-7819-6-67
PG 4
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA 366JE
UT WOS:000260476200001
PM 18577204
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Sagar, S
   Kumar, S
   Gupta, A
   Singhal, M
   Mishra, B
AF Sagar, Sushma
   Kumar, Subodh
   Gupta, Amit
   Singhal, Maneesh
   Mishra, Biplab
TI Successful Management of a Case of Primary Cutaneous Mucormycosis in an
   Immunocompetent Host
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE cutaneous mucormycosis; vacuum-assisted closure; immunocompetent host
ID ZYGOMYCOSIS; INFECTIONS; THERAPY
AB Primary cutaneous mucormycosis is a rare disease in the immunocompetent, and research on this condition is limited to case reports. Clinical presentation is not sufficiently distinctive to allow a diagnosis and the immunocompetent state precludes even the suspicion of the condition. There is agreement in literature regarding the absence of guidelines for its treatment. Most reports have used a combination of aggressive and repeated surgical debridement and systemic antifungals, usually amphotericin B. The authors propose the use of vacuum-assisted closure technology in managing these wounds with a possible role in decreasing the number and extent of debridement and limiting deeper tissue damage.
C1 [Sagar, Sushma; Kumar, Subodh; Gupta, Amit; Singhal, Maneesh; Mishra, Biplab] All India Inst Med Sci, Jai Prakash Narayan Apex Trauma Ctr, New Delhi 110029, India.
C3 All India Institute of Medical Sciences (AIIMS) New Delhi; Jai Prakash
   Narayan Apex Trauma Center
RP Kumar, S (通讯作者)，All India Inst Med Sci, Jai Prakash Narayan Apex Trauma Ctr, Room 306, New Delhi 110029, India.
EM subodh6@gmail.com
RI sagar, sushma/K-5397-2019; Kumar, Subodh/JYP-8905-2024
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NR 24
TC 0
Z9 1
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD MAY
PY 2013
VL 25
IS 5
BP 136
EP 140
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 154CL
UT WOS:000319649000006
PM 25866894
DA 2026-07-24
ER

PT J
AU Yousaf, M
   Witherow, A
   Gardiner, KR
   Gilliland, R
AF Yousaf, M
   Witherow, A
   Gardiner, KR
   Gilliland, R
TI Use of vacuum-assisted closure for healing of a persistent perineal
   sinus following panproctocolectomy: Report of a case
SO DISEASES OF THE COLON & RECTUM
LA English
DT Article
DE perineal sinus; negative pressure dressing; vacuum-assisted closure
ID INFLAMMATORY BOWEL-DISEASE; RECTAL EXCISION; MUSCLE FLAP; MANAGEMENT;
   PROCTECTOMY
AB Perineal sinus is a troublesome complication after proctectomy for inflammatory bowel disease or rectal cancer. The results from treatment with simple dressings with or without surgical debridement are suboptimal. Definitive management may require complex operations with muscular or musculocutaneous flaps. Vacuum-assisted dressings have been used successfully for management of chronic wounds and soft tissue defects. This technique was successfully used in the management of a perineal sinus, which occurred after proctectomy for rectal cancer developing on a background of inflammatory bowel disease and preoperative radiotherapy.
C1 Altnagelvin Hosp, Dept Surg, Derry BT47 6SB, Londonderry, North Ireland.
   Royal Victoria Hosp, Dept Surg, Belfast BT12 6BA, Antrim, North Ireland.
RP Gilliland, R (通讯作者)，Altnagelvin Hosp, Dept Surg, Glenshane Rd, Derry BT47 6SB, Londonderry, North Ireland.
EM rgilliland@alt.n.nhs.uk
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 24
TC 20
Z9 25
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0012-3706
EI 1530-0358
J9 DIS COLON RECTUM
JI Dis. Colon Rectum
PD AUG
PY 2004
VL 47
IS 8
BP 1403
EP 1407
DI 10.1007/s10350-004-0576-1
PG 5
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 852JJ
UT WOS:000223751300020
PM 15484357
DA 2026-07-24
ER

PT J
AU Al-Subhi, FS
   Zuker, RM
   Cole, WG
AF Al-Subhi, F. S.
   Zuker, R. M.
   Cole, W. G.
TI Vacuum-assisted closure as a surgical assistant in life-threatening
   necrotizing fasciitis in children
SO CANADIAN JOURNAL OF PLASTIC SURGERY
LA English
DT Article
DE Acute; Fasciitis; Necrotizing; Vacuum-assisted negative pressure
AB Necrotizing fasciitis is a severe soft tissue infection that can involve skin, subcutaneous fat, fascia and muscle. It can result in devastating sequelae including tissue necrosis, sepsis, toxic shock syndrome, cardiopulmonary collapse and death. To control rapidly spreading necrosis, early diagnosis and aggressive surgical treatment with extensive radical debridement of the affected areas is necessary, as well as systemic administration of broad-spectrum antimicrobials and, very often, intensive care support.
   The subatmospheric negative pressure dressing has been previously used in acute and complex wounds management. The concept of using vacuum-assisted closure dressing as another management component is presented in the current article.
C1 [Zuker, R. M.] Hosp Sick Children, Div Plast Surg, Toronto, ON M5G 1X8, Canada.
   Hosp Sick Children, Div Orthoped Surg, Toronto, ON M5G 1X8, Canada.
   Univ Toronto, Dept Surg, Toronto, ON, Canada.
C3 University of Toronto; Hospital for Sick Children (SickKids); University
   of Toronto; Hospital for Sick Children (SickKids); University of Toronto
RP Zuker, RM (通讯作者)，Hosp Sick Children, Div Plast Surg, Suite 5416,555 Univ Ave, Toronto, ON M5G 1X8, Canada.
EM ronald.zuker@sickkids.ca
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1997, ANN PLAST SURG, V38, P577
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
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   Huang WS, 2006, ASIAN J SURG, V29, P133
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NR 9
TC 11
Z9 16
U1 0
U2 3
PU PULSUS GROUP INC
PI OAKVILLE
PA 2902 S SHERIDAN WAY, OAKVILLE, ONTARIO L6J 7L6, CANADA
SN 1195-2199
J9 CAN J PLAST SURG
JI Can. J. Plast. Surg.
PD WIN
PY 2010
VL 18
IS 4
BP 139
EP 142
DI 10.1177/229255031001800412
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 694LY
UT WOS:000285300900008
PM 22131841
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Wang, F
   Zhu, H
   Wang, XQ
AF Wang, Fang
   Zhu, Huan
   Wang, Xiaoqiang
TI Vacuum-assisted closure combined with screw fixation for lower limb
   degloving injury associated with fractures and tibiofibular dislocation:
   A case report
SO ASIAN JOURNAL OF SURGERY
LA English
DT Letter
DE Lower limb degloving injury; Closed negative-pressure drainage; Screw
   fixation; Multiple fractures with distal tibiofibular joint dislocation
C1 [Wang, Fang] Gansu Prov Second Peoples Hosp, Dept Orthopaed, 1 Hezheng West Rd, Lanzhou 730000, Gansu, Peoples R China.
   [Zhu, Huan] Gansu Univ Chinese Med, Clin Sch Tradit Chinese Med, 35 Dingxi East Rd, Lanzhou 730000, Gansu, Peoples R China.
   [Wang, Xiaoqiang] Gansu Prov Hosp Tradit Chinese Med, Dept Orthoped Reconstruct, 418 Guazhou Rd, Lanzhou 730050, Gansu, Peoples R China.
C3 Gansu University of Chinese Medicine
RP Wang, XQ (通讯作者)，Gansu Prov Hosp Tradit Chinese Med, Dept Orthoped Reconstruct, 418 Guazhou Rd, Lanzhou 730050, Gansu, Peoples R China.
EM 15002504885@163.com
FU Fundamental Research Funds for the Central Universities [31920200092]
FX Supported by the Fundamental Research Funds for the Central Universities
   (31920200092)
CR McDonald C, 2021, J FOOT ANKLE SURG, V60, P615, DOI 10.1053/j.jfas.2020.09.010
NR 1
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SINGAPORE PTE LTD
PI SINGAPORE
PA 3 KILLINEY ROAD 08-01, WINSLAND HOUSE 1, SINGAPORE, 239519, SINGAPORE
SN 1015-9584
EI 0219-3108
J9 ASIAN J SURG
JI Asian J. Surg.
PD APR
PY 2026
VL 49
IS 4
BP 2192
EP 2193
DI 10.1016/j.asjsur.2025.07.328
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FV1EZ
UT WOS:001728115300001
OA gold
DA 2026-07-24
ER

PT J
AU Okike, K
   Bhattacharyya, T
AF Okike, Kanu
   Bhattacharyya, Timothy
TI Trends in the management of open fractures - A critical analysis
SO JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
LA English
DT Review
ID OPEN TIBIAL FRACTURES; PRESSURE PULSATILE LAVAGE; VACUUM-ASSISTED
   CLOSURE; BONE MORPHOGENETIC PROTEIN-2; LOCAL ANTIBIOTIC-THERAPY; OPEN
   EXTREMITY FRACTURES; SOFT-TISSUE COVERAGE; INTRAMEDULLARY NAILS;
   EXTERNAL FIXATION; FEMORAL-SHAFT
C1 Massachusetts Gen Hosp, Partners Orthopaed Trauma Serv, Boston, MA 02114 USA.
   Brigham & Womens Hosp, Boston, MA 02115 USA.
C3 Harvard University; Harvard University Medical Affiliates; Massachusetts
   General Hospital; Harvard University; Harvard University Medical
   Affiliates; Brigham & Women's Hospital
RP Okike, K (通讯作者)，Harvard Univ, 64 Linnaean St, Cambridge, MA 02138 USA.
OI Okike, Kanu/0000-0001-9310-9969
CR Adili A, 2002, J ORTHOP TRAUMA, V16, P413, DOI 10.1097/00005131-200207000-00008
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   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 102
TC 147
Z9 192
U1 0
U2 13
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0021-9355
EI 1535-1386
J9 J BONE JOINT SURG AM
JI J. Bone Joint Surg.-Am. Vol.
PD DEC
PY 2006
VL 88A
IS 12
BP 2739
EP 2748
DI 10.2106/JBJS.F.00146
PG 10
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 114AW
UT WOS:000242640100025
PM 17142427
DA 2026-07-24
ER

PT J
AU Song, ZH
   Guo, XJ
   Zhang, XL
AF Song, Zhihong
   Guo, Xiaojuan
   Zhang, Xiaoli
TI Effects of topical oxygen therapy on chronic traumatic wounds and its
   impact on granulation tissue
SO AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
LA English
DT Article
DE Chronic traumatic wounds; topical oxygen therapy; efficacy; granulation
   tissue
AB Objective: To evaluate the effects of topical oxygen therapy and its impacts on granulation tissue in patients with chronic traumatic wounds. Method: A total of 112 patients with chronic traumatic wounds were randomly divided into the control group (n=56, receiving negative-pressure wound therapy) and the intervention group (n=56, receiving negative-pressure wound therapy plus topical oxygen therapy) using a random number table and they were treated continuously for 2 weeks. Then, the scores from the Pressure Ulcer Scale for Healing (PUSH), the coverage rate of granulation tissue, the severity of pain and Transcutaneous Oxygen Partial Pressure (TcPO2) before and after treatment were compared between the two groups. Also, the bacterial culture-positive rate, the healing rate and the healing time were compared between the two groups. Results: The PUSH scores were significantly decreased after treatment compated to those before treatment in the two groups, and those in the intervention group were lower than those in the control group (all P<0.05). The coverage rate of granulation tissue gradually increased in the two groups from day 3 to day 14 after treatment, with that in the intervention group being higher than in the control group during the same period (all P<0.05). The bacterial culture-positive rate that was detected was significantly lower after treatment than that before treatment in the intervention group, and lower in the intervention group than in the control group after treatment (all P<0.05). The VAS scores significantly decreased and TcPO2 increased after treatment compared to those before treatment in the two groups, with changes in the intervention group being more significant than those in the control group (all P<0.05). During the 3-month follow-up, the wound healing rate was higher and the healing time shorter in the intervention group than those in the control group (all P<0.05). Conclusion: Negative-pressure wound therapy plus topical oxygen therapy can substantially increase the coverage rate of granulation tissue and TcPO2 at the traumatic site, thus facilitating the healing process and shortening the time for healing. So, the efficacy of negative-pressure wound therapy in combination with topical oxygen therapy is more effective in treating patients with chronic traumatic wounds than negative-pressure wound therapy alone.
C1 [Song, Zhihong] Inner Mongolia Med Univ, Affiliated Hosp, Dept Pulmonary & Crit Care Med, Hohhot, Mongolia.
   [Guo, Xiaojuan] Inner Mongolia Med Univ, Affiliated Hosp, Dept Gastrointestinal Surg, Hohhot, Mongolia.
   [Zhang, Xiaoli] Inner Mongolia Med Univ, Affiliated Hosp, Dept Surg Clin, 1 Tongdao St, Hohhot 010050, Mongolia.
C3 Inner Mongolia Medical University; Inner Mongolia Medical University;
   Inner Mongolia Medical University
RP Zhang, XL (通讯作者)，Inner Mongolia Med Univ, Affiliated Hosp, Dept Surg Clin, 1 Tongdao St, Hohhot 010050, Mongolia.
EM zxl15047809819@126.com
CR Alisauskaite N, 2017, PLOS ONE, V12, DOI 10.1371/journal.pone.0187746
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NR 22
TC 12
Z9 16
U1 0
U2 8
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1943-8141
J9 AM J TRANSL RES
JI Am. J. Transl. Res.
PY 2021
VL 13
IS 6
BP 7294
EP 7299
PG 6
WC Oncology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Research & Experimental Medicine
GA TC4EZ
UT WOS:000668595100097
PM 34306496
DA 2026-07-24
ER

PT J
AU Chandrasekhar, V
   Sureshkumar, S
   Manwar, AS
   Elamurugan, TP
   Nelson, T
   Anandhi, A
   Palanivel, C
AF Chandrasekhar, Vihari
   Sureshkumar, Sathasivam
   Manwar, Ali S.
   Elamurugan, T. P.
   Nelson, Thirugnanasambandam
   Anandhi, Amaranathan
   Palanivel, Chinnakali
TI Negative Pressure Wound Therapy Compared to Petrolatum Gauze and a
   Bogota Bag to Manage Postoperative Midline Abdominal Wound Dehiscence: A
   Pilot, Nonrandomized Controlled Trial
SO WOUND MANAGEMENT & PREVENTION
LA English
DT Article
DE clinical trial; surgical wound dehiscence; negative pressure wound
   therapy; granulation tissue; length of stay
ID VACUUM-ASSISTED CLOSURE; FASCIAL CLOSURE; OPEN ABDOMEN; HERNIA RATE
AB Treating postoperative abdominal wound dehiscence following abdominal surgery using negative pressure wound therapy (NPWT) has shown promising results. PURPOSE: A study was conducted to evaluate the efficacy of NPWT for fascial closure/cutaneous cover compared to non-NPWT treatment using petrolatum gauze and a Bogota bag in patients with postoperative laparotomy wound dehiscence. METHODS: A single center, prospective, nonrandomized pilot study was conducted. Using convenience sampling methods, consecutive patients on 6 different surgical units who were at least 18 years of age and who developed postoperative abdominal wound dehiscence following elective and emergency laparotomy from January 2017 to December 2018 were recruited. NPWT dressing with polyvinyl white foam sponge or loosely packed, saline-soaked petrolatum gauze followed by Bogota bag application were used and compared. Baseline patient demographics and history were collected, and patients were followed for an average of 6 months after surgery. Number of days until first signs of granulation tissue appearance, time until complete granulation tissue cover/fascial surgical closure, and hospital discharge were compared. Categorical variables (gender, comorbidities, presence or absence of stoma, exposure to prior radiotherapy) were expressed as proportions and analyzed using chi-squared test or Fischer's exact test. Continuous variables such as age, body mass index, albumin, postoperative hospital stay, and number of days required for decision for fascial closure were expressed as Mean +/- standard deviation and analyzed using an independent t test or Mann Whitney U test based on whether the data followed normal distribution. Postoperative day of wound dehiscence, the number of days for the appearance of granulation tissue, and the number of NPWT placements required also were assessed using Mean +/- standard deviation and analyzed using an independent t test. A P value <.05 was considered significant. RESULTS: Sixty (60) patients were included, but 4 in NPWT group and 10 in the non-NPWT group could not complete the study, leaving 26 patients in NPWT group and 20 patients in non-NPWT group. Demographic and surgical variables were not significantly different. Patients in both groups achieved complete wound coverage by surgical closure or healing by secondary intention. Days until first signs of granulation tissue (2.92 vs. 6.65; P <.001), number of days until fascial closure (15.50 vs. 29.50; P <.001), and length of postoperative hospital stay (24.30 vs. 37.90; P <.001) were significantly less in NPWT group. Two (2) patients (7.6%) in the NPWT developed a fistula during the 6-month follow-up period. No fistulas developed in the control group, and no intra-abdominal abscesses, ventral hernias, or wound dehiscence were reported in either group. CONCLUSION: Time until first signs of granulation tissue appearance and complete granulation tissue coverage was significantly shorter in the NPWT group, but time until definitive closure was not evaluated. Randomized, controlled clinical studies to compare definitive time to wound closure and long-term follow up to evaluate long-term complication rates, including the risk of developing fistulas, are warranted.
C1 [Chandrasekhar, Vihari; Sureshkumar, Sathasivam; Manwar, Ali S.; Elamurugan, T. P.; Nelson, Thirugnanasambandam] Jawaharlal Inst Postgrad Med Educ & Res JIPMER, Pondicherry, India.
   [Anandhi, Amaranathan] Jawaharlal Inst Postgrad Med Educ & Res JIPMER, Dept Gen Surg, Pondicherry, India.
   [Palanivel, Chinnakali] Jawaharlal Inst Postgrad Med Educ & Res JIPMER, Dept Prevent & Social Med, Pondicherry, India.
C3 Jawaharlal Institute of Postgraduate Medical Education & Research;
   Jawaharlal Institute of Postgraduate Medical Education & Research;
   Jawaharlal Institute of Postgraduate Medical Education & Research
RP Sureshkumar, S (通讯作者)，JIPMER, Surg, Pondicherry 605006, India.
EM drsureshkumar08@gmail.com
RI Amaranathan, Anandhi/K-1169-2019; T P, Elamurugan/IUQ-4480-2023;
   Chinnakali, Palanivel/N-8659-2013
OI Chinnakali, Palanivel/0000-0001-8320-1016
CR Amer H, 2017, EGYPT J SURG, V36, P199, DOI 10.4103/1110-1121.211706
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   Heller L, 2006, AM J SURG, V191, P165, DOI 10.1016/j.amjsurg.2005.09.003
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NR 18
TC 1
Z9 2
U1 0
U2 11
PU HMP
PI MALVERN
PA 70 E SWEDESFORD RD, STE 100, MALVERN, PA 19355 USA
SN 2640-5237
EI 2640-5245
J9 WOUND MANAG PREV
JI Wound Manag. Prev.
PD MAY
PY 2020
VL 66
IS 5
BP 37
EP 44
DI 10.25270/wmp.2020.5.3845
PG 8
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA OR3DY
UT WOS:000589355400003
PM 32401733
DA 2026-07-24
ER

PT J
AU Costa, ML
   Achten, J
   Bruce, J
   Davis, S
   Hennings, S
   Willett, K
   Petrou, S
   Jeffery, S
   Griffin, D
   Parker, B
   Masters, J
   Lamb, SE
   Tutton, E
   Parsons, N
AF Costa, Matthew L.
   Achten, Juul
   Bruce, Julie
   Davis, Sonia
   Hennings, Susie
   Willett, Keith
   Petrou, Stavros
   Jeffery, Steven
   Griffin, Damian
   Parker, Ben
   Masters, James
   Lamb, Sarah E.
   Tutton, Elizabeth
   Parsons, Nick
TI Negative-pressure wound therapy versus standard dressings for adults
   with an open lower limb fracture: the WOLLF RCT
SO HEALTH TECHNOLOGY ASSESSMENT
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; COST-EFFECTIVENESS ANALYSIS; PATIENTS
   EXPERIENCES; RANDOMIZED-TRIAL; HEALTH; CARE; RECOVERY; PATIENT; TRAUMA;
   PAIN
AB Background: Open fractures of the lower limb occur when a broken bone penetrates the skin and is exposed to the outside environment. These are life-changing injuries. The risk of deep infection may be as high as 27%. The type of dressing applied after surgical debridement could potentially reduce the risk of infection in the open-fracture wound.
   Objectives: To assess the disability, rate of deep infection, quality of life and resource use in patients with severe open fracture of the lower limb treated with negative-pressure wound therapy (NPWT) versus standard wound management after the first surgical debridement of the wound.
   Design: A pragmatic, multicentre randomised controlled trial.
   Setting: Twenty-four specialist trauma hospitals in the UK Major Trauma Network.
   Participants: A total of 460 patients aged >= 16 years with a severe open fracture of the lower limb were recruited from July 2012 through to December 2015. Patients were excluded if they presented more than 72 hours after their injury or were unable to complete questionnaires.
   Interventions: Negative-pressure wound therapy (n = 226) where an 'open-cell' solid foam or gauze was placed over the surface of the wound and connected to a suction pump which created a partial vacuum over the dressing versus standard dressings not involving negative pressure (n = 234).
   Main outcome measures: Disability Rating Index (DRI) - a score of 0 (no disability) to 100 (completely disabled) at 12 months was the primary outcome measure, with a minimal clinically important difference of 8 points. The secondary outcomes were deep infection, quality of life and resource use collected at 3, 6, 9 and 12 months post randomisaton.
   Results: There was no evidence of a difference in the patients' DRI at 12 months. The mean DRI in the NPWT group was 45.5 points [standard deviation (SD) 28.0 points] versus 42.4 points (SD 24.2 points) in the standard dressing group, giving a difference of -3.9 points (95% confidence interval -8.9 to 1.2 points) in favour of standard dressings (p = 0.132). There was no difference in HRQoL and no difference in the number of surgical site infections or other complications at any point in the 12 months after surgery. NPWT did not reduce the cost of treatment and it was associated with a low probability of cost-effectiveness.
   Limitations: Owing to the emergency nature of the interventions, we anticipated that some patients who were randomised into the trial would subsequently be unable or unwilling to take part. Such post-randomisation withdrawal of patients could have posed a risk to the external validity of the trial. However, the great majority of these patients (85%) were found to be ineligible after randomisation. Therefore, we can be confident that the patients who took part were representative of the population with severe open fractures of the lower limb.
   Conclusions: Contrary to the existing literature and current clinical guidelines, NPWT dressings do not provide a clinical or an economic benefit for patients with an open fracture of the lower limb.
   Future work: Future work should investigate alternative strategies to reduce the incidence of infection and improve outcomes for patients with an open fracture of the lower limb. Two specific areas of potentially great benefit are (1) the use of topical antibiotic preparations in the open-fracture wound and (2) the role of orthopaedic implants with antimicrobial coatings when fixing the associated fracture.
C1 [Costa, Matthew L.; Achten, Juul; Bruce, Julie; Davis, Sonia; Hennings, Susie; Petrou, Stavros; Griffin, Damian; Parker, Ben; Lamb, Sarah E.; Parsons, Nick] Univ Warwick, Warwick Med Sch, Clin Trials Unit, Coventry, W Midlands, England.
   [Costa, Matthew L.; Griffin, Damian] Univ Hosp Coventry & Warwickshire NHS Trust, Coventry, W Midlands, England.
   [Costa, Matthew L.; Achten, Juul; Willett, Keith; Masters, James; Lamb, Sarah E.; Tutton, Elizabeth] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford Trauma, Oxford, England.
   [Jeffery, Steven] Selly Oak Hosp, Birmingham, W Midlands, England.
C3 University of Warwick; University of Warwick; University of Oxford
RP Costa, ML (通讯作者)，Univ Warwick, Warwick Med Sch, Clin Trials Unit, Coventry, W Midlands, England.; Costa, ML (通讯作者)，Univ Hosp Coventry & Warwickshire NHS Trust, Coventry, W Midlands, England.; Costa, ML (通讯作者)，Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford Trauma, Oxford, England.
EM Matthew.Costa@ndorms.ox.ac.uk
RI Petrou, Stavros/ABD-8323-2021; Masters, James/U-8764-2019; Parsons,
   Nick/AAA-8713-2019; Achten, Juul/KUD-8515-2024; Bruce,
   Julie/G-7588-2014; /A-5207-2013
OI Petrou, Stavros/0000-0003-3121-6050; Griffin,
   Damian/0000-0003-0952-7848; Costa, Matthew/0000-0003-3644-1388;
   Hennings, Susie/0000-0002-8160-6658; Masters, James/0000-0001-9663-8858;
   Parsons, Nick/0000-0001-9975-888X; Tutton,
   Elizabeth/0000-0003-3973-360X; Achten, Juul/0000-0002-8857-5743; Lamb,
   Sarah/0000-0003-4349-7195; Bruce, Julie/0000-0002-8462-7999; 
FU Medical Research Council [G0501681, G0700452] Funding Source: Medline;
   The Dunhill Medical Trust [DMT/RCS605] Funding Source: Medline;
   Department of Health [10/57/20] Funding Source: Medline; Economic and
   Social Research Council [1499410] Funding Source: researchfish; Medical
   Research Council [G0501681, G0700452] Funding Source: researchfish;
   National Institute for Health Research [NF-SI-0616-10103, 10/57/20]
   Funding Source: researchfish; The Dunhill Medical Trust [DMT/RCS605]
   Funding Source: researchfish; MRC [G0501681] Funding Source: UKRI
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NR 100
TC 37
Z9 42
U1 0
U2 6
PU NIHR JOURNALS LIBRARY
PI SOUTHAMPTON
PA UNIV SOUTHAMPTON, EVALUATION, TRIALS & STUDIES COORDINATING CENTRE,
   ALPHA HOUSE, ENTERPRISE RD, SOUTHAMPTON, SO16 7NS, ENGLAND
SN 1366-5278
EI 2046-4924
J9 HEALTH TECHNOL ASSES
JI Health Technol. Assess.
PD DEC
PY 2018
VL 22
IS 73
BP 1
EP +
DI 10.3310/hta22730
PG 164
WC Health Care Sciences & Services
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Health Care Sciences & Services
GA HE7MU
UT WOS:000453622600001
PM 30573002
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Krticka, M
   Ira, D
   Nekuda, V
   Svancara, J
   Masek, M
AF Krticka, M.
   Ira, D.
   Nekuda, V.
   Svancara, J.
   Masek, M.
TI Effect of Negative Pressure Wound Therapy on Infectious Complications in
   Grade III Open Fractures
SO ACTA CHIRURGIAE ORTHOPAEDICAE ET TRAUMATOLOGIAE CECHOSLOVACA
LA Czech
DT Article
DE open fracture; negative pressure wound therapy; continual wound lavage;
   infection
ID VACUUM-ASSISTED CLOSURE; OPEN TIBIAL FRACTURES
AB PURPOSE OF THE STUDY
   Grade III open fractures are associated with infectious complications in 25-66% of injuries. Negative pressure wound therapy (NPWT) applied to an injured soft tissue coverage provides an impermeable barrier between the injured structures and the external environment, in addition to early secretion draining and a positive effect on the site of application. All this also prevents secondary bacterial contamination.
   The objective of the study was to compare the results of treatment methods in view of infectious complications in patients with soft tissue injury in grade-III open fractures managed either by NPWT and primary closure or by covering with combined dressing fabric (COM) in combination with continual wound lavage.
   MATERIAL AND METHODS
   This retrospective study comprised 77 patients with 80 grade III open fractures treated in the years 2008-2012; of these, 39 patients with 41 fractures met the inclusion criteria and were finally evaluated. The patients were divided into two groups. The control group included 19 patients with 20 fractures treated by the standard surgical procedure using stabilisation with an external fixator or intramedullary nail, thorough soft tissue debridement, continual wound lavage and suture of skin lesions or using a primary coverage of the defect with COM. The trial group consisted of 20 patients with 21 fractures treated according to the same principle, but NPWT was applied to injured soft tissue coverage first and skin suture or any other type of skin defect coverage was carried out when the healing process was good and bacteriological findings were negative. The results of both methods were evaluated based on the following criteria: development of superficial or deep infection in the wound, interval to negative bacteriological findings and osteomyelitis rate. The results were analysed by Fisher's exact test and the Man Whitney U test.
   RESULTS
   Infectious complications were recorded in a total of 15 (37%) fractures: 11 (55%) in the control group and four (19.1%) in the trial group (p = 0.025). Recurrent infection was observed in five control group fractures (25%) and in none of the trial group fractures (p = 0.021). Osteomyelitis was found only in two control group fractures. The average interval before negative bacteriological results were obtained was 22 days in the control group and 12 days in the trial group (p = 0.001).
   DISCUSSION
   The NPWT use as a temporary coverage of soft tissue defects in open fractures results in a significant reduction of infectious complications, as shown by many relevant studies including this study. In comparison with Gopal's "fix and flap" concept, the NPWT in our patient group had slightly higher incidence of infectious complications (15.4% versus 19.1%). However, these results can be achieved only if a specialist in reconstructive surgery and appropriate technical facilities are readily available. If this is not possible, then the NPWT, in comparison with conventional methods, provides the best possible way of temporary protection for an injured soft tissue coverage.
   CONCLUSIONS
   Application of NPWT within the primary treatment of injured soft tissue coverage in grade III open fractures results in a statistically significant reduction of bacterial contamination at the site of injury, as well as a reduction of the subsequent incidence of infectious complications. Primary application of NPWT also significantly reduced the risk of recurrent infection.
C1 [Krticka, M.; Ira, D.; Nekuda, V.; Masek, M.] FN Brno, Klin Urazove Chirurg, Jihlayska 20, Brno 62500, Czech Republic.
   [Krticka, M.; Ira, D.; Nekuda, V.; Masek, M.] Masarykovy Univ Brno, LF, Brno, Czech Republic.
   [Svancara, J.] Masarykovy Univ Brno, Lekarske Fak, Inst Biostat & Anal, Brno, Czech Republic.
   [Svancara, J.] Masarykovy Univ Brno, Prirodovedecke Fak, Brno, Czech Republic.
C3 University Hospital Brno; Masaryk University; Institute of Biostatistics
   & Analyses; Masaryk University; Masaryk University
RP Krticka, M (通讯作者)，FN Brno, Klin Urazove Chirurg, Jihlayska 20, Brno 62500, Czech Republic.
EM milan.krticka@fnbrno.cz
RI Švancara, Jan/G-5285-2017; Ira, Daniel/ABD-7164-2020; Krtička,
   Milan/ABE-1428-2020; Nekuda, Vladimír/ABF-7187-2020
OI Švancara, Jan/0000-0003-1692-3339; Ira, Daniel/0000-0002-7332-9830;
   Krtička, Milan/0000-0002-7101-1896; Masek, Michal/0000-0001-9368-8825;
   Nekuda, Vladimír/0000-0003-0644-8378
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NR 24
TC 7
Z9 7
U1 0
U2 12
PU GALEN SRO
PI PRAGUE 5
PA NA BELIDLE 34, PRAGUE 5, 150 00, CZECH REPUBLIC
SN 0001-5415
J9 ACTA CHIR ORTHOP TR
JI Acta Chir. Orthop. Traumatol. Cechoslov.
PD APR
PY 2016
VL 83
IS 2
BP 117
EP 122
PG 6
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA DL6EQ
UT WOS:000375732900008
PM 27167417
DA 2026-07-24
ER

PT J
AU Zwanenburg, PR
   Tol, BT
   Obdeijn, MC
   Lapid, O
   Gans, SL
   Boermeester, MA
AF Zwanenburg, Pieter R.
   Tol, Berend T.
   Obdeijn, Miryam C.
   Lapid, Oren
   Gans, Sarah L.
   Boermeester, Marja A.
TI Response to the Comment on "Meta-Analysis, Meta-Regression, and GRADE
   Assessment of Randomized and Nonrandomized Studies of Incisional
   Negative Pressure Wound Therapy Versus Control Dressings for the
   Prevention of Postoperative Wound Complications'' Reply
SO ANNALS OF SURGERY
LA English
DT Letter
ID SURGICAL SITE INFECTIONS; GENERAL-SURGERY; RISK
C1 [Zwanenburg, Pieter R.; Tol, Berend T.] Univ Amsterdam, Amsterdam UMC, Amsterdam Infect & Immun, Amsterdam Gastroenterol & Metab,Dept Surg, Amsterdam, Netherlands.
   [Obdeijn, Miryam C.; Lapid, Oren] Univ Amsterdam, Amsterdam UMC, Dept Plast Reconstruct & Hand Surg, Amsterdam, Netherlands.
   [Gans, Sarah L.; Boermeester, Marja A.] Univ Amsterdam, Amsterdam Infect & Immun, Amsterdam UMC, Dept Surg Amsterdam Gastroenterol & Metab, Amsterdam, Netherlands.
C3 University of Amsterdam; University of Amsterdam; University of
   Amsterdam
RP Boermeester, MA (通讯作者)，Univ Amsterdam, Amsterdam Infect & Immun, Amsterdam UMC, Dept Surg Amsterdam Gastroenterol & Metab, Amsterdam, Netherlands.
EM m.a.boermeester@amsterdamumc.nl
RI Lapid, Oren/S-6331-2019
OI Lapid, Oren/0000-0001-8921-9866; Boermeester, Marja/0000-0003-3890-8105
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   Selvaggi Francesco, 2014, Surg Technol Int, V24, P83
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   Zwanenburg PR, 2019, ANN SURG
   Zwanenburg PR., PRESSURE TRIAL REGIS
NR 19
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0003-4932
EI 1528-1140
J9 ANN SURG
JI Ann. Surg.
PD DEC
PY 2021
VL 274
IS 6
BP E699
EP E700
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WX3XK
UT WOS:000718532600075
PM 32187029
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Pezzella, AT
   Ferraris, VA
   Lancey, RA
AF Pezzella, AT
   Ferraris, VA
   Lancey, RA
TI Care of the adult cardiac surgery patient: Part II - Respiratory system
SO CURRENT PROBLEMS IN SURGERY
LA English
DT Review
ID CORONARY-ARTERY-BYPASS; AORTIC-VALVE-REPLACEMENT; DELAYED STERNAL
   CLOSURE; BRACHIAL-PLEXUS INJURY; OPEN-HEART OPERATIONS; PHRENIC-NERVE
   INJURY; C-REACTIVE PROTEIN; MULTIMODALITY BLOOD CONSERVATION;
   VACUUM-ASSISTED CLOSURE; CRITICALLY-ILL PATIENTS
C1 Good Samaritan Hosp, Mt Vernon, IL USA.
   Univ Kentucky, Div Cardiovasc & Thorac Surg, Lexington, KY 40506 USA.
   Bassett Heart Care Inst, Div Cardiac Surg, Cooperstown, NY USA.
C3 University of Kentucky
RP Pezzella, AT (通讯作者)，Good Samaritan Hosp, Mt Vernon, IL USA.
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NR 280
TC 1
Z9 1
U1 0
U2 8
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0011-3840
EI 1535-6337
J9 CURR PROB SURG
JI Curr. Probl. Surg.
PD JUN
PY 2004
VL 41
IS 6
BP 526
EP 574
DI 10.1067/j.cpsurg.2004.04.001
PG 49
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 839FM
UT WOS:000222768900002
PM 15226701
DA 2026-07-24
ER

PT J
AU Lazar, HL
   Salm, TV
   Engelman, R
   Orgill, D
   Gordon, S
AF Lazar, Harold L.
   Salm, Thomas Vander
   Engelman, Richard
   Orgill, Dennis
   Gordon, Steven
TI Prevention and management of sternal wound infections
SO JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Review
DE guidelines; prevention; sternal wound infection; treatment
ID SURGICAL-SITE INFECTIONS; VACUUM-ASSISTED CLOSURE; STAPHYLOCOCCUS-AUREUS
   BACTEREMIA; GENTAMICIN-COLLAGEN SPONGE; PRACTICE GUIDELINE SERIES; TIGHT
   GLYCEMIC CONTROL; LONG-TERM SURVIVAL; HIGH-RISK PATIENTS;
   CARDIAC-SURGERY; METHICILLIN-RESISTANT
C1 [Lazar, Harold L.] Boston Med Ctr, Div Cardiac Surg, 88 East Newton St,B402, Boston, MA 02118 USA.
   [Salm, Thomas Vander] Massachusetts Gen Hosp, Div Cardiac Surg, Boston, MA 02114 USA.
   [Engelman, Richard] Baystate Med Ctr, Div Cardiac Surg, Springfield, MA USA.
   [Orgill, Dennis] Brigham & Womens Hosp, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
   [Gordon, Steven] Cleveland Clin, Div Infect Dis, Cleveland, OH 44106 USA.
C3 Boston Medical Center; Harvard University; Harvard University Medical
   Affiliates; Massachusetts General Hospital; Baystate Medical Center;
   Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Cleveland Clinic Foundation
RP Lazar, HL (通讯作者)，Boston Med Ctr, Div Cardiac Surg, 88 East Newton St,B402, Boston, MA 02118 USA.
EM harold.l.lazar@gmail.com
RI Orgill, Dennis/H-7596-2019
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NR 101
TC 205
Z9 237
U1 0
U2 13
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0022-5223
EI 1097-685X
J9 J THORAC CARDIOV SUR
JI J. Thorac. Cardiovasc. Surg.
PD OCT
PY 2016
VL 152
IS 4
BP 962
EP 972
DI 10.1016/j.jtcvs.2016.01.060
PG 11
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA EA6OO
UT WOS:000386748700018
PM 27555340
OA Bronze
DA 2026-07-24
ER

PT J
AU Benedix, F
   Lippert, H
   Meyer, F
AF Benedix, F.
   Lippert, H.
   Meyer, F.
TI Etiology, Diagnosis and Treatment of Lymphocutaneous Fistulas,
   Chylascites and Chylothorax as Infrequent but Serious Complications
   Following Surgical Procedures
SO ZENTRALBLATT FUR CHIRURGIE
LA English
DT Editorial Material
ID VACUUM-ASSISTED CLOSURE; OF-THE-LITERATURE; CHYLOUS ASCITES;
   POSTOPERATIVE CHYLOTHORAX; LYMPHATIC FISTULAS; THORACIC-DUCT; ARTERIAL
   RECONSTRUCTION; PERCUTANEOUS CATHETERIZATION; DOXYCYCLINE TREATMENT;
   PLEURAL EFFUSION
C1 [Benedix, F.; Lippert, H.; Meyer, F.] Univ Magdeburg, Klin Allgemeine Viszeral & Gefasschirurg, D-39106 Magdeburg, Germany.
C3 Otto von Guericke University
RP Meyer, F (通讯作者)，Univ Klinikum Magdeburg AOR, Klin Allgemeine Viszeral & Gefasschirurg, Leipziger Str 44, D-39120 Magdeburg, Germany.
EM frankbenedix@gmx.de
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NR 69
TC 13
Z9 13
U1 0
U2 5
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD DEC
PY 2012
VL 137
IS 6
BP 580
EP 586
DI 10.1055/s-0030-1262632
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 095FP
UT WOS:000315320400023
PM 21563052
DA 2026-07-24
ER

PT J
AU Zargar, HR
   Mohsin, M
   Shah, RA
   Yasir, M
   Bhat, TA
   Wani, AH
AF Zargar, Haroon R.
   Mohsin, Mir
   Shah, Raheeb A.
   Yasir, Mir
   Bhat, Tanveer A.
   Wani, Adil H.
TI Successful management of complex scalp wounds with exposed calvarial
   bones by customized Negative pressure wound therapy (NPWT): Case series
   and review of the literature
SO TROPICAL DOCTOR
LA English
DT Review
DE Calvarium; negative pressure wound therapy; scalp; wounds; injuries;
   drill holes
AB Scalp wounds with exposed calvarial bones continue to be a challenge especially when no local flap options are available and no microvascular flaps can be performed. Our prospective study looked at 19 patients (14 males) where customized negative pressure wound treatment was used till the complex scalp wounds, mostly from animal bites, were covered with healthy granulation and grafted. Scalp wounds ranged from 6 x 4 cm to 17 x 11 cm in size whereas the area of exposed bone ranged from 1 x 2 cm to 10 x 10 cm. No major complication was seen, and wounds were rapidly healed.
C1 [Zargar, Haroon R.; Mohsin, Mir; Shah, Raheeb A.; Yasir, Mir; Bhat, Tanveer A.; Wani, Adil H.] Sheri Kashmir Inst Med Sci, Dept Plast & Reconstruct Surg, Srinagar 190011, J&K, India.
C3 Sher-i-Kashmir Institute of Medical Sciences
RP Mohsin, M (通讯作者)，Sheri Kashmir Inst Med Sci, Dept Plast & Reconstruct Surg, Srinagar 190011, J&K, India.
EM m_mohsin@rediffmail.com
RI Mohsin, Mir/AAA-1246-2022
OI Mohsin, Mir/0000-0001-8503-2543; , Raheeb Ahmad Shah/0009-0006-5845-8649
CR Dedmond BT, 2007, J ORTHOP TRAUMA, V21, P11, DOI 10.1097/BOT.0b013e31802cbc54
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   Gurtner GC, 2000, PLAST RECONSTR SURG, V106, P672, DOI 10.1097/00006534-200009030-00025
   Kim YH, 2015, J WOUND CARE, V24, P536, DOI 10.12968/jowc.2015.24.11.536
   Liu X, 2018, INT J SURG, V53, P72, DOI 10.1016/j.ijsu.2018.02.064
   Mohsin M, 2017, INDIAN J PLAST SURG, V50, P43, DOI 10.4103/ijps.IJPS_196_16
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Orgill DP, 2011, PLAST RECONSTR SURG, V127, p105S, DOI 10.1097/PRS.0b013e318200a427
   Virani Siddharth R, 2016, J Clin Orthop Trauma, V7, P256, DOI 10.1016/j.jcot.2016.05.007
NR 9
TC 1
Z9 1
U1 0
U2 2
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0049-4755
EI 1758-1133
J9 TROP DOCT
JI Trop. Dr.
PD APR
PY 2022
VL 52
IS 2
BP 258
EP 261
AR 00494755211043377
DI 10.1177/00494755211043377
EA JAN 2022
PG 4
WC Public, Environmental & Occupational Health; Tropical Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 2H3QB
UT WOS:000740971200001
PM 34985345
DA 2026-07-24
ER

PT J
AU Sun, SQ
   Zhu, MT
   Wen, CH
AF Sun, Shaoqin
   Zhu, Mengting
   Wen, Changhui
TI Probable pyoderma gangrenosum complicated with cutaneous Aspergillus
   flavus infection: case report
SO FRONTIERS IN MEDICINE
LA English
DT Article
DE <italic>Aspergillus flavus</italic>; cutaneous aspergillosis; negative
   pressure wound therapy; pyoderma gangrenosum; voriconazole
ID PRESSURE WOUND THERAPY
AB Pyoderma gangrenosum (PG) is a rare, chronic, autoinflammatory neutrophilic dermatosis. Its typical clinical manifestations include painful papules and pustules surrounded by erythema on the lower extremities and trunk, which gradually progress to form well-demarcated, painful ulcers with undermined edges. Due to impaired skin barrier function, prolonged wound exposure, and the frequent need for immunosuppressive therapy, PG patients are highly susceptible to secondary infections. We report here a clinical case of successful treatment with glucocorticoids and voriconazole, combined with multiple sessions of negative-pressure wound therapy and skin grafting, in a patient with cutaneous Aspergillus flavus infection and possible pyoderma gangrenosum.
C1 [Sun, Shaoqin; Wen, Changhui] Guizhou Univ Tradit Chinese Med, Affiliated Hosp 1, Dept Dermatol, Guiyang, Guizhou, Peoples R China.
   [Zhu, Mengting] Guizhou Univ Tradit Chinese Med, Guiyang, Guizhou, Peoples R China.
C3 Guizhou University of Traditional Chinese Medicine; Guizhou University
   of Traditional Chinese Medicine
RP Wen, CH (通讯作者)，Guizhou Univ Tradit Chinese Med, Affiliated Hosp 1, Dept Dermatol, Guiyang, Guizhou, Peoples R China.
EM wenchanghui163@163.com
CR Biermann N, 2023, J TISSUE VIABILITY, V32, P613, DOI 10.1016/j.jtv.2023.06.010
   Douglas AP, 2021, INTERN MED J, V51, P143, DOI 10.1111/imj.15591
   Eisendle K, 2020, ADV WOUND CARE, V9, P405, DOI 10.1089/wound.2020.1160
   Merad Y, 2021, PATHOGENS, V10, DOI 10.3390/pathogens10060643
   Moltrasio C, 2025, SEMIN IMMUNOPATHOL, V47, DOI 10.1007/s00281-025-01064-7
   Nacea DI, 2025, J FUNGI, V11, DOI [10.3390/jof11040281, 10.3390/jof11040281]
   Nie B, 2016, J WOUND CARE, V25, P617, DOI 10.12968/jowc.2016.25.11.617
   Nishimura M, 2022, J CLIN MED, V11, DOI 10.3390/jcm11236924
   Suoniemi L, 2024, INT WOUND J, V21, DOI [10.1111/iwj.14943, 10.1111/iwj.14943]
NR 9
TC 0
Z9 0
U1 0
U2 0
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
EI 2296-858X
J9 FRONT MED-LAUSANNE
JI Front. Med.
PD APR 22
PY 2026
VL 13
AR 1806433
DI 10.3389/fmed.2026.1806433
EA APR 2026
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA HL2LB
UT WOS:001756711200001
PM 42100284
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Sun, SY
   Wang, C
   Chen, DW
   Cen, SQ
   Lv, XJ
   Wen, XR
   Liu, M
   Lu, WS
   Zhao, JC
   Ran, XW
AF Sun, Shuyao
   Wang, Chun
   Chen, Dawei
   Cen, Shiqiang
   Lv, Xiaoju
   Wen, Xiaorong
   Liu, Min
   Lu, Wusheng
   Zhao, Jichun
   Ran, Xingwu
TI Combating Superbug Without Antibiotic on a Postamputation Wound in a
   Patient With Diabetic Foot
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE autologous platelet-rich gel; diabetic foot; multidrug-resistant
   bacterial infection; negative pressure wound therapy
ID RICH PLASMA GEL; NEGATIVE-PRESSURE; LEUKOCYTE; THERAPY; ULCERS
AB Diabetic foot is a kind of limb- and life-threatening complication that is difficult to treat with conventional therapy, especially when accompanied with peripheral arterial insufficiency and severe infection. We present a diabetic patient with a postamputation wound infected by multidrug-resistant Acinetobacter baumannii/haemolyticus, which was resistant to almost all antibiotics. As the clinical response to antimicrobial therapy was poor, antibiotic was discontinued. Autologous platelet-rich gel with anticoagulation, negative pressure wound therapy, and improvement of microcirculation were used successfully to eradicate infection of the superbug and achieve final wound closure.
C1 [Sun, Shuyao; Wang, Chun; Chen, Dawei; Cen, Shiqiang; Lv, Xiaoju; Wen, Xiaorong; Liu, Min; Lu, Wusheng; Zhao, Jichun; Ran, Xingwu] Sichuan Univ, West China Hosp, Chengdu 610064, Sichuan, Peoples R China.
C3 Sichuan University
RP Ran, XW (通讯作者)，Sichuan Univ, West China Hosp, Dept Endocrinol & Metab, Diabet Foot Care Ctr, 37 Guo Xue Xiang, Chengdu 610041, Sichuan, Peoples R China.
EM ranxingwu@163.com
RI Chen, Dawei/V-4296-2019; Zhao, Ji-Chun/GWM-8456-2022
FU National Natural Science Foundation of China [81170776]; Science and
   Technology Bureau of Sichuan Province, China [2009sz0153]
FX The author(s) disclosed receipt of the following financial support for
   the research, authorship, and/or publication of this article: This study
   was supported in part by Grant 81170776 from the National Natural
   Science Foundation of China and Grant 2009sz0153 from the Science and
   Technology Bureau of Sichuan Province, China.
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NR 17
TC 11
Z9 15
U1 1
U2 27
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD MAR
PY 2016
VL 15
IS 1
BP 74
EP 77
DI 10.1177/1534734615595736
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA DF9QY
UT WOS:000371697400014
PM 26238676
DA 2026-07-24
ER

PT J
AU Drerup, C
   Schlarb, D
AF Drerup, Christian
   Schlarb, Dominik
TI Surgical treatment for chronic leg ulcer
SO HAUTARZT
LA German
DT Article
DE Split-thickness skin graft; Mesh graft; Negative pressure wound therapy;
   Ulcer therapy; Wound healing
ID PRESSURE WOUND THERAPY; THICKNESS SKIN-GRAFT
AB Leg ulcers pose a therapeutic challenge due to a chronic healing process. Conservative wound dressings are initially the treatment of choice, but their effectiveness in therapy-refractory wounds is limited. In these cases, multiple mechanical debridement in combination with split-thickness skin grafts (STSG) are a simple and safe treatment option for ulcer coverage. Additional therapy with negative pressure wound therapy (NPWT) improves the surgical outcome by promoting ulcer granulation, continuous elimination of exsudate and blood as well as increased contact pressure on the skin graft. After transplantation, the split skin graft requires daily wound dressings until it has fully healed after approximately 3 weeks.
C1 [Drerup, Christian; Schlarb, Dominik] Univ Klinikum Munster, Klin Hautkrankheiten Allgemeine Dermatol & Venero, Von Esmarch Str 58, D-48149 Munster, Germany.
C3 University of Munster
RP Schlarb, D (通讯作者)，Univ Klinikum Munster, Klin Hautkrankheiten Allgemeine Dermatol & Venero, Von Esmarch Str 58, D-48149 Munster, Germany.
EM Dominik.Schlarb@ukmuenster.de
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NR 13
TC 1
Z9 1
U1 0
U2 8
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0017-8470
EI 1432-1173
J9 HAUTARZT
JI Hautarzt
PD SEP
PY 2020
VL 71
IS 9
SI SI
BP 715
EP 723
DI 10.1007/s00105-020-04661-9
EA AUG 2020
PG 9
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA NJ0ZK
UT WOS:000561691500001
PM 32827047
DA 2026-07-24
ER

PT J
AU Jaffe, L
   Wu, SC
AF Jaffe, Leland
   Wu, Stephanie C.
TI Dressings, Topical Therapy, and Negative Pressure Wound Therapy
SO CLINICS IN PODIATRIC MEDICINE AND SURGERY
LA English
DT Article
DE Wounds; Dressings; Topical therapy; Negative pressure wound therapy
ID REGENERATED CELLULOSE/COLLAGEN MATRIX; SILVER DRESSINGS;
   CONTROLLED-TRIAL; GROWTH-FACTORS; FOOT ULCERS; MANAGEMENT; PROTEASES;
   EXPRESSION; GUIDELINES; OUTCOMES
AB The current epidemic of diabetes has created a high demand for skilled wound-care professionals. Wound-care treatment begins with an appreciation of the cause of the ulceration and an adherence to the fundamental pillars of wound care. Also critical in the wound management paradigm is the optimization of the wound environment to facilitate the progression through the stages of healing. This can be accomplished through the use of different topical therapies and wound dressings to generate a favorable condition conducive to healing. This article summarizes the updated literature and best practices related to this topic.
C1 [Jaffe, Leland] Rosalind Franklin Univ, Dr William M Scholl Coll Podiatr Med, Dept Med & Radiol, N Chicago, IL 60064 USA.
   [Wu, Stephanie C.] Rosalind Franklin Univ Med & Sci, Dr William M Scholl Coll Podiatr Med, CLEAR, Ctr Stem Cell & Regenerat Med,Dept Podiatr Surg &, 3333 Green Bay Rd, N Chicago, IL 60064 USA.
C3 Rosalind Franklin University of Medicine & Science; Rosalind Franklin
   University of Medicine & Science
RP Jaffe, L (通讯作者)，Rosalind Franklin Univ, Dr William M Scholl Coll Podiatr Med, Dept Med & Radiol, N Chicago, IL 60064 USA.
EM leland.jaffe@rosalindfranklin.edu
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NR 57
TC 22
Z9 26
U1 0
U2 24
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0891-8422
EI 1558-2302
J9 CLIN PODIATR MED SUR
JI Clin. Podiatr. Med. Surg.
PD JUL
PY 2019
VL 36
IS 3
BP 397
EP +
DI 10.1016/j.cpm.2019.02.005
PG 16
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA IC2QP
UT WOS:000470805100007
PM 31079606
DA 2026-07-24
ER

PT J
AU Awad, T
   Butcher, M
AF Awad, T.
   Butcher, M.
TI Handling the sequelae of breast cancer treatment: use of NPWT to enhance
   patient independence
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE breast cancer; wound breakdown; negative pressure wound therapy; quality
   of life; care partnership
ID QUALITY-OF-LIFE
AB A cancer diagnosis can be an overwhelming experience and has devastating implications for an individual, their family and friends. Radical treatment, although often essential, can have its own health consequences. This case study describes the management of a 38-year-old woman with a portable, non-electrical negative pressure wound therapy device, suggesting benefits in terms of healing, patient independence and improved quality of life. The case study also highlights the importance of effective communication, patient involvement and empowerment in clinical decision-making, showing that an effective client-clinician relationship can help overcome the physical and emotional sequelae of this diagnosis.
C1 [Awad, T.] BUPA Cromwell Hosp, London, England.
   [Butcher, M.] South West Wound Care Consultancy, S Tyneside, Devon, England.
RP Awad, T (通讯作者)，BUPA Cromwell Hosp, London, England.
EM m.butcher_woundcare@hotmail.com
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NR 24
TC 5
Z9 5
U1 0
U2 2
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD MAR
PY 2013
VL 22
IS 3
BP 162
EP 166
DI 10.12968/jowc.2013.22.3.162
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology
GA 098BR
UT WOS:000315519600008
PM 23665735
DA 2026-07-24
ER

PT J
AU Petit-Clair, N
   Smith, M
   Chernev, I
AF Petit-Clair, N.
   Smith, M.
   Chernev, I.
TI Modified NPWT using round channel drain for pacemaker pocket non-healing
   complex wound: a case report
SO JOURNAL OF WOUND CARE
LA English
DT Review
DE round channel drain; negative pressure wound therapy; wound closure;
   pacemaker
ID ELECTRONIC DEVICE INFECTIONS; MANAGEMENT; THERAPY
AB Infection of cardiovascular implantable electronic devices poses a serious medical problem. Management of infected pocket wounds may be challenging for the physician and cause prolonged morbidity for the patient. The mainstay of treatment for infected cardiovascular implantable electronic devices is complete removal of the infected device and appropriate antibiotic therapy. In contrast, removal is not required for superficial or incisional infection at the pocket site if there is no involvement of the device. Here, we describe a modified negative pressure wound therapy (NPWT) technique using a round channel drain for pacemaker pocket non-healing complex wound, which started as a superficial incisional wound infection.
C1 [Petit-Clair, N.; Smith, M.] Avalon Univ, Sch Med, Youngstown, OH 44505 USA.
   [Smith, M.] Appalachian Reg Healthcare, Dept Surg, Beckley, WV USA.
   [Chernev, I.] Appalachian Reg Healthcare, Dept Med, Beckley, WV USA.
   [Chernev, I.] West Virginia Sch Osteopath Med, Lewisburg, WV USA.
RP Petit-Clair, N (通讯作者)，Avalon Univ, Sch Med, Youngstown, OH 44505 USA.
EM ivantchernev@yahoo.com
CR Baddour LM, 2010, CIRCULATION, V121, P458, DOI 10.1161/CIRCULATIONAHA.109.192665
   Mansoor J, 2013, INT WOUND J
   McGarry TJ, 2014, EUROPACE, V16, P372, DOI 10.1093/europace/eut305
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   Voigt A, 2010, PACE, V33, P414, DOI 10.1111/j.1540-8159.2009.02569.x
NR 7
TC 2
Z9 3
U1 0
U2 2
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
J9 J WOUND CARE
JI J. Wound Care
PD SEP
PY 2014
VL 23
IS 9
BP 453
EP 455
DI 10.12968/jowc.2014.23.9.453
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA AP0QY
UT WOS:000341769000008
PM 25284298
DA 2026-07-24
ER

PT J
AU Nolff, MC
   Meyer-Lindenberg, A
AF Nolff, M. C.
   Meyer-Lindenberg, A.
TI Necrotising fasciitis in a domestic shorthair cat - negative pressure
   wound therapy assisted debridement and reconstruction
SO JOURNAL OF SMALL ANIMAL PRACTICE
LA English
DT Article
ID SKIN; CLOSURE; MANAGEMENT; DIAGNOSIS
AB A 10-year-old, domestic shorthair cat was presented for acute lameness of the left forelimb accompanied by severe pain, swelling, skin necrosis, malodorous discharge and pyrexia. Following a presumptive diagnosis of necrotising fasciitis aggressive surgical debridement of the affected soft tissues of the antebrachium and negative pressure wound treatment of the open defect were performed. Surgical findings supported the tentative diagnosis of necrotising fasciitis and Streptococcus canis was isolated from the wound. A free skin graft was performed 29 days after admission, and augmented by 3 days of negative pressure wound therapy to facilitate graft incorporation. Healing was achieved without complications and no functional or aesthetic abnormalities remained.
C1 [Nolff, M. C.; Meyer-Lindenberg, A.] Univ Munich, Clin Small Anim Surg & Reprod, Munich, Germany.
C3 University of Munich
RP Nolff, MC (通讯作者)，Univ Munich, Clin Small Anim Surg & Reprod, Munich, Germany.
RI Meyer-Lindenberg, Andrea/H-1076-2011; Nolff, Mirja/W-6756-2019
OI Meyer-Lindenberg, Andrea/0000-0001-6137-3773; Nolff,
   Mirja/0000-0001-9317-7769
CR Anaya DA, 2007, CLIN INFECT DIS, V44, P705, DOI 10.1086/511638
   Angoules AG, 2007, INJURY, V38, pS19, DOI 10.1016/j.injury.2007.10.030
   [Anonymous], ANTISEPTICS SURG
   [Anonymous], 34 ANN M AM BURN ASS
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   Cuccia G, 2009, UROL INT, V82, P426, DOI 10.1159/000218532
   Cunningham JD, 2001, MT SINAI J MED, V68, P253
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   Gupta S, 2012, INT WOUND J, V9, P40, DOI 10.1111/j.1742-481X.2012.01019.x
   Hess MO, 2009, J SMALL ANIM PRACT, V50, P558, DOI 10.1111/j.1748-5827.2009.00789.x
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Naidoo SL, 2005, J AM ANIM HOSP ASSOC, V41, P104, DOI 10.5326/0410104
   Owen LJ, 2009, VET COMP ORTHOPAED, V22, P417, DOI 10.3415/VCOT-08-12-0123
   Simman R, 2004, WOUNDS, V16, P76
   Stanley BJ, 2013, VET SURG, V42, P511, DOI 10.1111/j.1532-950X.2013.12005.x
   Steinstraesser L, 2009, INT J LOW EXTR WOUND, V8, P28, DOI 10.1177/1534734609331991
   Sura R, 2008, VET REC, V162, P450, DOI 10.1136/vr.162.14.450
   Veenstra RP, 2001, INTENS CARE MED, V27, P1831, DOI 10.1007/s001340101070
NR 22
TC 12
Z9 12
U1 0
U2 23
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0022-4510
EI 1748-5827
J9 J SMALL ANIM PRACT
JI J. Small Anim. Pract.
PD APR
PY 2015
VL 56
IS 4
BP 281
EP 284
DI 10.1111/jsap.12275
PG 4
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA CE4BN
UT WOS:000351775900009
PM 25323110
DA 2026-07-24
ER

PT J
AU Li, XJ
   Zhang, YR
   Xiong, F
   Li, JY
   Qi, SL
   Wang, QB
   Mu, SJ
   Cao, D
   Niu, S
   Liu, W
   Liu, LC
   Zhang, ZT
AF Li, Xinjian
   Zhang, Yuru
   Xiong, Fang
   Li, Jiayan
   Qi, Shunli
   Wang, Qingbo
   Mu, Shijia
   Cao, Di
   Niu, Shuo
   Liu, Wei
   Liu, Liancheng
   Zhang, Zhongtao
TI Comparison between vacuum sealing drainage (VSD) and conventional
   dressing for fournier's gangrene: a single-centre retrospective study
SO BMC SURGERY
LA English
DT Article
DE Fournier's gangrene (FG); Vacuum sealing drainage (VSD); Laboratory risk
   indicator for necrotizing fasciitis (LRINEC) scoring system; inverse
   probability of treatment weight (IPTW)
ID NECROTIZING FASCIITIS; ASSISTED CLOSURE; WOUND THERAPY; MANAGEMENT
AB BackgroundFournier's gangrene (FG) is a life-threatening infection associated with high mortality and often necessitates urgent surgical intervention. Vacuum sealing drainage (VSD) has emerged as a promising adjunct to surgical debridement; however, its impact on antibiotic stewardship remains inadequately studied. This study compares the efficacy of VSD and conventional dressings in the management of FG. MethodsIn this single-center retrospective study, 104 patients with Fournier's gangrene (FG) treated between January 2022 and December 2023 were analyzed. Patients were categorized into VSD (n = 42) and conventional dressing (n = 62) groups following surgical debridement. Data included demographics, comorbidities, infection sites, Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) scores, antibiotic duration, and clinical outcomes. Inverse probability of treatment weighting (IPTW) was applied to mitigate confounding biases. ResultsBefore IPTW adjustment, the VSD group exhibited longer durations in key clinical outcomes compared to the control group, including time to leukocyte normalization (+ 1.6 days), antibiotic use (+ 2.0 days), and hospital stay (+ 2.0 days). After IPTW adjustment, all three indicators showed improvement in favor of the VSD group. Generalized weighted regression further confirmed that VSD was associated with significant clinical benefits: shortened time to leukocyte normalization (mean difference: -1.8 days; 90% CI: -3.5 to -0.1), reduced duration of antibiotic therapy (-2.0 days; 90% CI: -3.7 to -0.4), and decreased length of hospitalization (-3.0 days; 90% CI:-5.7 to -0.4).Post-IPTW, VSD emerged as a protective factor, with all standardized mean differences (SMDs) remaining below 0.2, indicating acceptable covariate balance. ConclusionsVSD may improve clinical outcomes in patients with Fournier's gangrene by accelerating recovery and reducing antibiotic use and length of hospitalization. These benefits appear more pronounced in patients with high LRINEC scores or extensive infections. Nevertheless, individualized treatment strategies should consider systemic disease severity, such as the Fournier's Gangrene Severity Index (FGSI).
C1 [Li, Xinjian; Zhang, Zhongtao] Capital Med Univ, Beijing Friendship Hosp, Dept Gen Surg, Beijing, Peoples R China.
   [Li, Xinjian; Zhang, Zhongtao] State Key Lab Digest Hlth, Beijing, Peoples R China.
   [Li, Xinjian; Zhang, Zhongtao] Natl Clin Res Ctr Digest, Beijing, Peoples R China.
   [Li, Xinjian; Zhang, Yuru; Mu, Shijia; Cao, Di; Niu, Shuo; Liu, Wei; Liu, Liancheng] Beijing Erlong Lu Hosp, Beijing Anorectal Hosp, Dept Proctol, Beijing, Peoples R China.
   [Xiong, Fang] Beijing Erlong Lu Hosp Fang Xiong, Beijing Anorectal Hosp, Dept Med Ultrason, Beijing, Peoples R China.
   [Li, Jiayan] Beijing Erlong Lu Hosp, Beijing Anorectal Hosp, Radiol Dept, Beijing, Peoples R China.
   [Qi, Shunli] Beijing Erlong Lu Hosp, Beijing Anorectal Hosp, Pathol Dept, Beijing, Peoples R China.
   [Wang, Qingbo] Beijing Erlong Lu Hosp, Beijing Anorectal Hosp, Clin Lab, Beijing, Peoples R China.
C3 Capital Medical University
RP Zhang, ZT (通讯作者)，Capital Med Univ, Beijing Friendship Hosp, Dept Gen Surg, Beijing, Peoples R China.; Zhang, ZT (通讯作者)，State Key Lab Digest Hlth, Beijing, Peoples R China.; Zhang, ZT (通讯作者)，Natl Clin Res Ctr Digest, Beijing, Peoples R China.; Liu, LC (通讯作者)，Beijing Erlong Lu Hosp, Beijing Anorectal Hosp, Dept Proctol, Beijing, Peoples R China.
EM llcell@163.com; zhangzht@ccmu.edu.cn
FU Beijing Anorectal Hospital (Beijing Erlong Lu Hospital)
FX Gratitude to all the healthcare professionals who played a crucial role
   in the treatment of Fournier's gangrene patients.
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NR 41
TC 0
Z9 0
U1 0
U2 4
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2482
J9 BMC SURG
JI BMC Surg.
PD OCT 15
PY 2025
VL 25
IS 1
AR 481
DI 10.1186/s12893-025-03242-8
PG 14
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 8RM1N
UT WOS:001595580900003
PM 41094492
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Achten, J
   Parsons, NR
   Bruce, J
AF Achten, J.
   Parsons, N. R.
   Bruce, J.
TI Protocol for a randomised controlled trial of standard wound management
   versus negative pressure wound therapy in the treatment of adult
   patients with an open fracture of the lower limb: UK Wound management of
   Open Lower Limb Fractures (UK WOLFF) (vol 5, e009087, 2015)
SO BMJ OPEN
LA English
DT Correction
RI Achten, Juul/KUD-8515-2024; Bruce, Julie/G-7588-2014; Parsons,
   Nick/AAA-8713-2019
OI Bruce, Julie/0000-0002-8462-7999; Parsons, Nick/0000-0001-9975-888X
CR Achten J, 2015, BMJ OPEN, V5, DOI 10.1136/bmjopen-2015-009087
NR 1
TC 0
Z9 0
U1 0
U2 3
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 2044-6055
J9 BMJ OPEN
JI BMJ Open
PY 2016
VL 6
IS 5
AR 009087corr1
DI 10.1136/bmjopen-2015-009087corr1
PG 1
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA DP3SF
UT WOS:000378414700006
OA gold
DA 2026-07-24
ER

PT J
AU Chen, QY
   Li, B
   Pan, L
AF Chen, Qin-Ying
   Li, Bei
   Pan, Li
TI Postoperative Anastomotic Leakage Complicated with Severe
   Intra-abdominal Infection and Peristomal Abscess after Colon Cancer
   Surgery: A Case Report
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
DE anastomotic leak; colorectal cancer; intra-abdominal infection;
   negative-pressure wound therapy; negative-pressure wound therapy with
   instillation and dwell time; peristomal abscess
ID INCONTINENCE-ASSOCIATED DERMATITIS; ETIOLOGY
AB Postoperative anastomotic leakage following surgery for colorectal cancer is a serious complication that is frequently associated with significant intra-abdominal infection and the formation of peristomal abscesses. Patients with this condition often present with complex medical comorbidities and face considerable challenges in achieving wound healing. In this case report, a 57-year-old man presented with colonic obstruction secondary to colon cancer and subsequently underwent curative surgery. Postoperatively, anastomotic leakage occurred, which necessitated resection of the anastomosis and the formation of a descending colostomy. The patient subsequently developed severe intra-abdominal infection and peristomal abscess, leading to impaired wound healing. Clinicians implemented a treatment regimen combining continuous negative-pressure wound therapy (NPWT) with intermittent NPWT with instillation and dwell time. This approach resulted in rapid wound healing. Ultimately, the patient successfully underwent colostomy closure, restoring gastrointestinal continuity. For abdominal wounds with severe fecal contamination and extensive separation of the dermis and subcutaneous tissues, the combination of continuous NPWT and intermittent NPWT with instillation and dwell time may be an efficacious therapeutic strategy.
C1 [Chen, Qin-Ying; Li, Bei; Pan, Li] Peking Univ, Dept Gastrointestinal Surg, Shenzhen Hosp, Shenzhen, Guangdong, Peoples R China.
   [Chen, Qin-Ying] Peking Univ, Head Wound & Ostomy Care Clin, Shenzhen Hosp, Shenzhen, Guangdong, Peoples R China.
C3 Peking University; Peking University
RP Chen, QY (通讯作者)，Peking Univ, Dept Gastrointestinal Surg, Shenzhen Hosp, Shenzhen, Guangdong, Peoples R China.; Chen, QY (通讯作者)，Peking Univ, Head Wound & Ostomy Care Clin, Shenzhen Hosp, Shenzhen, Guangdong, Peoples R China.
EM coralcqy@163.com; 21658366@qq.com; lipanmedicine@163.com
CR Acton C, 2020, J WOUND CARE, V29, P18, DOI 10.12968/jowc.2020.29.1.18
   Chabal LO, 2021, ADV SKIN WOUND CARE, V34, P293, DOI 10.1097/01.ASW.0000742888.02025.d6
   Chadi SA, 2016, J GASTROINTEST SURG, V20, P2035, DOI 10.1007/s11605-016-3255-3
   Chambers WM, 2004, BEST PRACT RES CL GA, V18, P865, DOI 10.1016/j.bpg.2004.06.026
   Chiarello MM, 2022, SURG ONCOL, V40, DOI 10.1016/j.suronc.2022.101708
   Giri P, 2021, ANN MED SURG, V61, P73, DOI 10.1016/j.amsu.2020.12.015
   Ichioka S, 2001, JPN J PRESSURE ULCER, V3, P32
   Kim PJ, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9047
   Kim PJ, 2020, INT WOUND J, V17, P1194, DOI 10.1111/iwj.13424
   Kim PJ, 2020, INT WOUND J, V17, P174, DOI 10.1111/iwj.13254
   Koudounas S, 2020, J WOUND OSTOMY CONT, V47, P388, DOI 10.1097/WON.0000000000000656
   O'Flynn Sinead Kelly, 2019, Br J Nurs, V28, pS6, DOI [10.12968/bjon.2019.28.5.s6, 10.12968/bjon.2019.28.5.S6]
   Orgill DP, 2013, INT WOUND J, V10, P15, DOI 10.1111/iwj.12170
   Pappalardo Vincenzo, 2019, SURG TECHNOL INT, V34
   Rahbari NN, 2010, SURGERY, V147, P339, DOI 10.1016/j.surg.2009.10.012
   Schuren Jan, 2005, Int Wound J, V2, P230, DOI 10.1111/j.1742-4801.2005.00131.x
   Stormark K, 2020, COLORECTAL DIS, V22, P1108, DOI 10.1111/codi.14999
   Wang J, 2023, ADV SKIN WOUND CARE, V36, P481, DOI 10.1097/ASW.0000000000000016
NR 18
TC 1
Z9 2
U1 1
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD JUN
PY 2025
VL 38
IS 5
BP 274
EP 277
DI 10.1097/ASW.0000000000000286
PG 4
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA 2UM0H
UT WOS:001491600900008
PM 40117503
DA 2026-07-24
ER

PT J
AU Ideguchi, Y
   Ono, S
   Kaneyuku, S
   Murakami, T
   Ogawa, R
AF Ideguchi, Yuki
   Ono, Shimpei
   Kaneyuku, Shintaro
   Murakami, Taishi
   Ogawa, Rei
TI Reconstruction Using Negative Pressure Wound Therapy with a Cotton
   Filler for Fixation of Male Genital Skin Grafts in Cases of Fournier's
   Gangrene
SO JOURNAL OF NIPPON MEDICAL SCHOOL
LA English
DT Article
DE cotton filler; gauze based; negative pressure wound therapy; skin graft;
   genitalia
AB The reliable engraftment of skin grafts into areas with complex shapes can be challenging. Here, we report a case of successful fixation of a genital skin graft using negative pressure wound therapy (NPWT) with RENASYS (R) Cotton Filler. A 44-year-old male with no relevant medical history underwent split- thickness skin grafting for a genital skin defect caused by Fournier's gangrene. A 0.4-mm sheet graft was applied for the penile skin defect, while 0.4-mm 1.5 times mesh grafting was applied for the testis and spermatic cord. NPWT with a cotton filler was used for seven days of fixation. No postoperative pain or stool contamination was observed. Although a small area of partial necrosis developed, the lesion healed with conservative treatment. Six months after surgery, there was no scar contracture, urination disorder, or pain during erection. Cotton fillers are highly malleable and adaptable, allowing for simple and reliable fixation of skin grafts in complex areas. Moreover, NPWT for genital graft fixation avoids contamination from stools. Therefore, we recommend fixation using NPWT with a cotton filler for genital skin grafting. (J Nippon Med Sch 2024; 91: 595 & horbar;599)
C1 [Ideguchi, Yuki; Kaneyuku, Shintaro; Murakami, Taishi] Aidu Chuo Hosp, Dept Plast Surg, 11 Tsurugamachi, Aizu Wakamatsu, Fukushima 9650011, Japan.
   [Ono, Shimpei; Ogawa, Rei] Nippon Med Coll Hosp, Dept Plast Reconstruct & Aesthet Surg, Tokyo, Japan.
C3 Nippon Medical School
RP Ideguchi, Y (通讯作者)，Aidu Chuo Hosp, Dept Plast Surg, 11 Tsurugamachi, Aizu Wakamatsu, Fukushima 9650011, Japan.
EM ideguchiyuki121@gmail.com
CR Akcan A, 2009, ULUS TRAVMA ACIL CER, V15, P342
   Borgquist O, 2011, OSTOMY WOUND MANAG, V57, P44
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   Zhao JC, 2013, INT WOUND J, V10, P407, DOI 10.1111/j.1742-481X.2012.00997.x
NR 19
TC 1
Z9 1
U1 0
U2 1
PU MEDICAL ASSOC NIPPON MEDICAL SCH
PI TOKYO
PA 1-1-5, SENDAGI, TOKYO, 113-8602, JAPAN
SN 1345-4676
EI 1347-3409
J9 J NIPPON MED SCH
JI J. Nippon Med. Sch.
PD DEC
PY 2024
VL 91
IS 6
BP 595
EP 599
DI 10.1272/jnms.JNMS.2024_91-610
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA T2I0A
UT WOS:001403296700013
PM 39756950
OA Green Published, gold
DA 2026-07-24
ER

PT J
AU Martinov, S
   Ortiz, S
AF Martinov, Sagi
   Ortiz, Soccoro
TI Ten-year follow-up of a case of necrotizing fasciitis successfully
   treated with negative-pressure wound therapy, dermal regeneration
   template application, and split- thickness skin autograft
SO ACTA CHIRURGICA BELGICA
LA English
DT Article
DE Necrotising fasciitis; plastic surgery; negative pressure wound therapy;
   dermal template; skin-grafting
AB Introduction: Necrotizing fasciitis is a rapidly progressive and often fatal infection of the fasciae and subcutaneous tissues.
   Patient and methods: In this case report, we present the treatment of a 63-year-old patient suffering from diabetes mellitus, who was admitted to the emergency unit for severe right gluteal pain, which had begun 24 hours before admission. Cutaneous symptoms, oliguria, metabolic acidosis, acute renal failure, severe hypotension, and tachycardia occurred, and the patient was admitted to Intensive Care a few hours after initial admission. The patient underwent a debridement of gluteal, abdominal, lower-thoracic, and upper thigh regions. Biopsy of fascia lata confirmed the suspected diagnosis of necrotizing fasciitis. Treatment included prompt surgical debridement, negative-pressure wound therapy, and dermal regeneration template application with fibrin glue, and subsequent split-thickness skin autografting.
   Results: After 10 years, elasticity of the skin and limb mobility are comparable to that in non-injured areas, and the patient is pain free.
   Conclusion: In our opinion, this combination should be a treatment of choice for large wounds in the patients with NF with multiple comorbidities.
C1 [Martinov, Sagi; Ortiz, Soccoro] Free Univ Brussels, Brugmann Univ Hosp, Dept Plast & Reconstruct Surg, Brussels, Belgium.
C3 Universite Libre de Bruxelles
RP Martinov, S (通讯作者)，Free Univ Brussels, Brugmann Univ Hosp, Brussels, Belgium.
EM Sagimartinov@gmail.com
RI Martinov, Sagi/GPC-4434-2022
OI Martinov, Sagi/0000-0001-8191-950X
CR Al-Subhi FS, 2010, CAN J PLAST SURG, V18, P139, DOI 10.1177/229255031001800412
   Bento-Rodrigues J, 2013, ACTA MEDICA PORT, V26, P456
   Chiummariello S, 2012, G CHIR, V33, P358
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   Mizuguchi Y, 2015, J NIPPON MED SCH, V82, P290, DOI 10.1272/jnms.82.290
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   Wong CH, 2004, CRIT CARE MED, V32, P1535, DOI 10.1097/01.CCM.0000129486.35458.7D
NR 10
TC 0
Z9 1
U1 0
U2 0
PU ACTA MEDICAL BELGICA
PI BRUSSELS
PA AVENUE CIRCULAIRE 138 A, B-1180 BRUSSELS, BELGIUM
SN 0001-5458
J9 ACTA CHIR BELG
JI Acta Chir. Belg.
PY 2018
VL 118
IS 2
BP 120
EP 124
DI 10.1080/00015458.2017.1316618
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GC9BJ
UT WOS:000430092200009
PM 28438078
DA 2026-07-24
ER

PT J
AU Smud-Orehovec, S
   Mance, M
   Haluzan, D
   Vrbanovic-Mijatovic, V
   Mijatovic, D
AF Smud-Orehovec, Sanda
   Mance, Marko
   Haluzan, Damir
   Vrbanovic-Mijatovic, Vilena
   Mijatovic, Davor
TI Defect Reconstruction of an Infected Diabetic Foot Using Split- and
   Full-thickness Skin Grafts With Adjuvant Negative Pressure Wound
   Therapy: A Case Report and Review of the Literature
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Review
DE Charcot foot; full-thickness skin graft; negative pressure wound
   therapy; split-thickness skin graft; diabetic foot; infection; foot
   reconstruction
ID IN-VITRO; ANTIMICROBIAL EFFICACY; ULCERS; RESISTANCE; BIOFILMS;
   BACTERIA; COLONIZATION; DRESSINGS; SILVER
AB Introduction. Any alteration or impairment to normal wound healing can result in the development of chronic wounds, which may lead to serious complications such as infection and loss of body fluid and proteins. Primary closure alone may not be sufficient to fulfill the criteria of successful defect reconstruction. Therefore, additional procedures such as skin grafting must be considered as an option. Case Report. The case of a 43-year-old woman with diabetes who was admitted to the University Hospital Rebro (Zagreb, Croatia) due to an infected, nonhealing wound on her left foot. Skin grafts combined with negative pressure wound therapy (NPWT) before and after graft application improved wound healing in this patient. Conclusions. In this patient, the combination of skin grafts with NPWT before and after graft application reduced the comorbidities and complications often seen in the diabetic patient population. Herein, the authors utilized a quicker, cost-efficient, and safer technique of wound closure compared with traditional nonsurgical methods.
C1 [Smud-Orehovec, Sanda; Mance, Marko; Mijatovic, Davor] Univ Hosp Rebro, Dept Plast Reconstruct & Aesthet Surg, Kispaticeva 12, Zagreb, Croatia.
   [Haluzan, Damir] Univ Hosp Rebro, Dept Vasc Surg, Zagreb, Croatia.
   [Vrbanovic-Mijatovic, Vilena] Univ Hosp Rebro, Dept Anesthesiol & ICU, Zagreb, Croatia.
RP Mance, M (通讯作者)，Univ Hosp Rebro, Dept Plast Reconstruct & Aesthet Surg, Kispaticeva 12, Zagreb, Croatia.
EM markomance@gmail.com
OI Vrbanović Mijatović, Vilena/0000-0001-8568-1359
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NR 61
TC 7
Z9 8
U1 0
U2 9
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD NOV
PY 2018
VL 30
IS 11
BP E108
EP E115
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA IV1VC
UT WOS:000484065900003
PM 30457564
DA 2026-07-24
ER

PT J
AU Lelong, AS
   Martelli, N
   Bonan, B
   Prognon, P
   Pineau, J
AF Lelong, Anne-Sophie
   Martelli, Nicolas
   Bonan, Brigitte
   Prognon, Patrice
   Pineau, Judith
TI Use of a risk assessment method to improve the safety of negative
   pressure wound therapy
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Negative pressure wound therapy; Risk analysis; Safety
ID MANAGEMENT; TISSUE
AB To conduct a risk analysis of the negative pressure wound therapy (NPWT) care process and to improve the safety of NPWT, a working group of nurses, hospital pharmacists, physicians and hospital managers performed a risk analysis for the process of NPWT care. The failure modes, effects and criticality analysis (FMECA) method was used for this analysis. Failure modes and their consequences were defined and classified as a function of their criticality to identify priority actions for improvement. By contrast to classical FMECA, the criticality index (CI) of each consequence was calculated by multiplying occurrence, severity and detection scores. We identified 13 failure modes, leading to 20 different consequences. The CI of consequences was initially 712, falling to 357 after corrective measures were implemented. The major improvements proposed included the establishment of 6-monthly training cycles for nurses, physicians and surgeons and the introduction of computerised prescription for NPWT. The FMECA method also made it possible to prioritise actions as a function of the criticality ranking of consequences and was easily understood and used by the working group. This study is, to our knowledge, the first to use the FMECA method to improve the safety of NPWT.
C1 [Lelong, Anne-Sophie; Martelli, Nicolas; Prognon, Patrice; Pineau, Judith] Georges Pompidou European Hosp, AP HP, Dept Pharm, F-75015 Paris, France.
   [Bonan, Brigitte] Foch Hosp, Dept Pharm, Suresnes, France.
C3 Assistance Publique Hopitaux Paris (APHP); Universite Paris Cite;
   Hopital Universitaire Europeen Georges-Pompidou - APHP; Hospital Foch
RP Martelli, N (通讯作者)，Georges Pompidou European Hosp, AP HP, Dept Pharm, 20 Rue Leblanc, F-75015 Paris, France.
EM nicolas.martelli@egp.aphp.fr
RI Martelli, Nicolas/ABB-2722-2021
OI Martelli, Nicolas/0000-0001-5959-231X
CR Ahmed F, 2010, J PLAST RECONSTR AES, V63, pE497, DOI 10.1016/j.bjps.2009.09.006
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   Kamolz LP, 2004, BURNS, V30, P253, DOI 10.1016/j.burns.2003.12.003
   KCI, 2010, VAC THER CLIN GUID R
   Lepage B, 2009, QUAL SAF HEALTH CARE, V18, P441, DOI 10.1136/qshc.2007.025742
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   US Food and Drug Administration. Center for Devices and Radiological Health, 2009, ADV PAT SER COMPL NE
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   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
NR 21
TC 1
Z9 2
U1 0
U2 8
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2014
VL 11
IS 3
BP 253
EP 258
DI 10.1111/j.1742-481X.2012.01081.x
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA AH8HJ
UT WOS:000336377600005
PM 22931525
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Wu, SC
   Armstrong, DG
AF Wu, Stephanie C.
   Armstrong, David G.
TI Clinical outcome of diabetic foot ulcers treated with negative pressure
   wound therapy and the transition from acute care to home care
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Diabetes; Lower extremity ulcer; Negative pressure wound therapy; VAC
   (R); Wound healing
AB Diabetic foot ulcers affect millions of people in the United States of America and impose tremendous medical, psychosocial and financial loss or burden. Negative pressure wound therapy (NPWT) is generally well tolerated and appears to stimulate a robust granulation tissue response compared with other wound healing modalities. This device may be a cost-effective adjunctive wound healing therapy. This literature review will focus on the clinical outcome of diabetic foot ulcers treated with NPWT, its implication in the transition from acute care to home care, factors that might influence clinical outcomes in home care as well as quality-of-life aspects in these patients. Patient care for diabetic foot ulceration is complex and necessitates multiprofessional collaboration to provide comprehensive wound care. It is clear that when we strive for limb preservation in this most high-risk population, it is important to have an available versatile, efficacious wound healing modality. There is a need for an easy transition from acute care to home care. Resources need to be combined in a collaborative and synergistic fashion to allow patient to perform many daily living activities while receiving the potential benefits of an advanced wound healing modality.
C1 [Wu, Stephanie C.; Armstrong, David G.] Rosalind Franklin Univ Med & Sci, Dr William M Scholl Coll Podiatr Med, Dept Surg, N Chicago, IL 60048 USA.
   [Wu, Stephanie C.; Armstrong, David G.] Rosalind Franklin Univ Med & Sci, Dr William M Scholl Coll Podiatr Med, CLEAR, N Chicago, IL 60048 USA.
   [Wu, Stephanie C.] Lutheran Gen Hosp, Advocate Med Grp, Natl Ctr Limb Salvage NCLP, Park Ridge, IL 60068 USA.
C3 Rosalind Franklin University of Medicine & Science; Rosalind Franklin
   University of Medicine & Science
RP Armstrong, DG (通讯作者)，Rosalind Franklin Univ Med & Sci, Dr William M Scholl Coll Podiatr Med, Dept Surg, 3333 Green Bay Rd, N Chicago, IL 60048 USA.
EM armstrong@usa.net
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NR 50
TC 26
Z9 30
U1 0
U2 14
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2008
VL 5
SU 2
BP 10
EP 16
DI 10.1111/j.1742-481X.2008.00466.x
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA V16AX
UT WOS:000207843600003
PM 18577133
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Vargo, D
AF Vargo, Daniel
TI Negative pressure wound therapy in the prevention of wound infection in
   high risk abdominal wound closures
SO AMERICAN JOURNAL OF SURGERY
LA English
DT Article
DE Wound infection; Risk stratification; Wound dressing
ID SURGICAL SITE INFECTIONS; INCISIONS; SCIP
AB BACKGROUND: Wound infections continue to be an issue in abdominal surgery. Tissue perfusion may be a contributing factor. Negative pressure application may have promise in decreasing wound complication.
   METHOD: A retrospective review of prospectively collected data in patients with high-risk abdominal wounds was undertaken. Comorbidities, risk factors for infection, wound classification, and wound outcomes were all evaluated. The primary outcome measure was wound infection rate. Secondary outcomes included device safety and overall surgical site complication rate.
   RESULTS: Thirty patients were identified who had skin flaps in whom negative pressure was used. Negative pressure was applied for an average of 5.6 days (range, 5-7 days). No patient developed ischemia or necrosis of the skin flaps. No wound infections were identified. The overall wound complication rate was 3%. The comparable historical control wound complication rate was 20%, and chi(2) analysis showed a statistically significant decrease in the infection rate with negative-pressure wound therapy (P < .05).
   CONCLUSIONS: Negative-pressure wound therapy applied to a closed, high-risk surgical wound is safe, with no evidence of skin necrosis and decreased wound infection rate. (C) 2012 Published by Elsevier Inc.
C1 Univ Utah, Sch Med, Dept Surg, Salt Lake City, UT 84112 USA.
C3 Utah System of Higher Education; University of Utah
RP Vargo, D (通讯作者)，Univ Utah, Sch Med, Dept Surg, Salt Lake City, UT 84112 USA.
EM daniel.vargo@hsc.utah.edu
CR Anderson DJ, 2011, INFECT DIS CLIN N AM, V25, P135, DOI 10.1016/j.idc.2010.11.004
   [Anonymous], NATL HOSP DISCHARGE
   Colli A, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-160
   Cruse P, 1981, REV INFECT DIS, V4, P734
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   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
NR 9
TC 39
Z9 47
U1 1
U2 10
PU EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
PI BRIDGEWATER
PA 685 ROUTE 202-206 STE 3, BRIDGEWATER, NJ 08807 USA
SN 0002-9610
J9 AM J SURG
JI Am. J. Surg.
PD DEC
PY 2012
VL 204
IS 6
BP 1021
EP 1023
DI 10.1016/j.amjsurg.2012.10.004
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 060UG
UT WOS:000312803000058
PM 23231938
DA 2026-07-24
ER

PT J
AU Cui, XH
   Yu, XY
   Wang, YY
   Li, FY
AF Cui, Xiaohong
   Yu, Xiaoyan
   Wang, Yanyan
   Li, Fangying
TI Comprehensive analysis to evaluate the effectiveness of interventions
   such as exercise, nutrition, and medication on muscle mass and function
   in elderly patients with sarcopenia: A meta-analysis
SO ASIAN JOURNAL OF SURGERY
LA English
DT Letter
DE Diabetic foot ulcer; Negative pressure wound therapy; Compound blood
   exhaust powder; Dorsal foot artery blood flow
C1 [Cui, Xiaohong; Wang, Yanyan; Li, Fangying] Zhejiang Hosp, Dept Geriatr, Hangzhou, Peoples R China.
   [Yu, Xiaoyan] Zhejiang Hosp, Gen Ward, 12 Lingyin Rd,Bldg 3,2nd Floor, Hangzhou 310000, Peoples R China.
RP Yu, XY (通讯作者)，Zhejiang Hosp, Gen Ward, 12 Lingyin Rd,Bldg 3,2nd Floor, Hangzhou 310000, Peoples R China.
EM tch335@126.com
CR Cannataro R, 2021, INT J MOL SCI, V22, DOI 10.3390/ijms22189724
   Duerksen DR, 2021, NUTR CLIN PRACT, V36, P942, DOI 10.1002/ncp.10613
   Meza-Valderrama D, 2021, NUTRIENTS, V13, DOI 10.3390/nu13030761
   Orsso CE, 2022, J CACHEXIA SARCOPENI, V13, P1442, DOI 10.1002/jcsm.12954
   Papadopoulou SK, 2021, NUTRIENTS, V13, DOI 10.3390/nu13124499
NR 5
TC 0
Z9 0
U1 1
U2 7
PU ELSEVIER SINGAPORE PTE LTD
PI SINGAPORE
PA 3 KILLINEY ROAD 08-01, WINSLAND HOUSE 1, SINGAPORE, 239519, SINGAPORE
SN 1015-9584
EI 0219-3108
J9 ASIAN J SURG
JI Asian J. Surg.
PD APR
PY 2025
VL 48
IS 4
BP 2536
EP 2537
DI 10.1016/j.asjsur.2024.10.087
EA JAN 2025
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 1VT6L
UT WOS:001474818100001
PM 39532641
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Lv, ZM
   Wang, YJ
   Chen, JL
   Zhang, QF
   Zhao, HT
AF Lv, Zhenmu
   Wang, Yujie
   Chen, Jingliang
   Zhang, Qingfu
   Zhao, Haitao
TI Pelnac® artificial dermis assisted by vacuum sealing drainage for
   treatment of severe avulsion injuries of the fingers
SO JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
LA English
DT Article
DE Artificial dermis; Pelnac; Severe avulsion injuries; Functional
   outcomes; Aesthetic outcomes
ID UPPER EXTREMITY; TISSUE DEFECTS
AB PurposeThis study aimed to evaluate the outcomes of Pelnac assisted by vacuum sealing drainage in managing severe avulsion injuries of the fingers.MethodsThis prospective study was conducted from May 2017 to September 2023, involving 12 consecutive patients with severe avulsion injuries of the fingers. Patients underwent single-stage or two-stage procedures employing Pelnac assisted by vacuum sealing drainage (VSD) for the management of severe avulsion injuries of the fingers. Post-operative follow-up was routinely scheduled, and aesthetic and functional outcomes, sensory recovery, complications were recorded.ResultsTwelve patients were included in the analysis, consisting of 9 males and 3 females, with a mean age of 30.6 +/- 11.0 years. All patients presented with severe damage to tendons and deep tissues, as well as varying degrees of bone exposure and injury, with average defect area of 36.9 cm(2) (range, 11 to 180 cm(2)). At the final follow-up (mean, 14 months; range, 12 to 29 months), the average score on the Fingertip Injuries Outcome Score (FIOS) was 14.3 (SD 3.9, range 10 to 22), with 6 patients achieving excellent result, 4 classified as good and 2 as fair. Patients reported an average satisfaction score of 74.0 (SD 11.6; range 51 to 94) regarding the aesthetic appearance. The average score on the Vancouver Scar Scale score was 2.3 (SD 2.1, range 1.0 to 7.4). Ten patients reported normal or near-normal sensation, while 2 patients experienced slight sensory loss. The average score on the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire was 13.2 (SD 8.5, range 0 to 47). No infections or hematomas were reported during hospitalization or after discharge.ConclusionPelnac, assisted by VSD, proved to be an effective approach for managing severe avulsion injuries of the fingers. This approach can be considered as a viable alternative for addressing severe injuries or complex wound conditions.
C1 [Lv, Zhenmu; Zhang, Qingfu] Hebei Med Univ, Hosp 3, Dept Burn & Wound Repair Ctr, 139 Ziqiang Rd, Shijiazhuang 050051, Hebei, Peoples R China.
   [Wang, Yujie] Hebei Prov Hosp Tradit Chinese Med, Dept Orthopaed Surg 4, 389 Zhongshan East Rd, Shijiazhuang 050000, Hebei, Peoples R China.
   [Chen, Jingliang] 82nd Grp Army Hosp Peoples Liberat Army, Dept Hand & Foot Surg, 991 Baihua East Rd, Baoding 071000, Hebei, Peoples R China.
   [Zhao, Haitao] Hebei Med Univ, Hosp 3, Dept Foot & Ankle Surg, 139 Ziqiang Rd, Shijiazhuang 050051, Hebei, Peoples R China.
C3 Hebei Medical University; Hebei University of Chinese Medicine; Hebei
   Medical University
RP Zhao, HT (通讯作者)，Hebei Med Univ, Hosp 3, Dept Foot & Ankle Surg, 139 Ziqiang Rd, Shijiazhuang 050051, Hebei, Peoples R China.
EM drzhenmulv@126.com; 378412581@qq.com; 575880829@qq.com;
   16601225@hebmu.edu.cn; drzhaohaitao@126.com
OI Li, Liqiang/0009-0001-5968-4772
FU Hebei Provincial Natural Science Foundation Project
FX We are grateful to J.F. Y.G. L.X. and W.W. of the Department of Burn and
   Wound Repair Center and Y.L. of the Department of Orthopaedic Surgery of
   Hebei Medical University Third Hospital for their kind assistance.
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NR 24
TC 1
Z9 1
U1 1
U2 4
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-799X
J9 J ORTHOP SURG RES
JI J. Orthop. Surg. Res.
PD FEB 4
PY 2025
VL 20
IS 1
AR 136
DI 10.1186/s13018-025-05547-z
PG 8
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA U8N7H
UT WOS:001414299200005
PM 39905439
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ren, LQ
   Zhang, CN
   Zhao, LH
   Li, CK
   Zhang, L
   Xue, X
AF Ren, Liqing
   Zhang, Cuina
   Zhao, Lihua
   Li, Cuikun
   Zhang, Li
   Xue, Xin
TI 被撤回的出版物: Influence of incentive nursing intervention on recovery of burn
   patients after vacuum sealing drainage (Retracted Article)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article; Retracted Publication
DE burn injury; comfort; inadequate drainage; incentive nursing
   intervention; pain intensity; vacuum sealing drainage
ID PRESSURE-WOUND-THERAPY; ASSISTED CLOSURE; SUBATMOSPHERIC PRESSURE;
   MANAGEMENT
AB To observe the effect of application of incentive nursing intervention (INI) on recovery in burn patients undergoing vacuum sealing drainage (VSD). From January 2017 to January 2020, a total of 82 consecutive burn patients were prospectively enrolled, and divided into INI group and routine nursing intervention (RNI) group according to random number table method. The causes of inadequate drainage were collected, the incidence was calculated, and the occurrence of inadequate drainage at different locations was compared. The pain degree and comfort status before and after the intervention were observed, and the wound healing time, hospital stay, and satisfaction after the intervention were recorded. The reasons for inadequate drainage during the treatment of VSD included negative pressure insufficient, drainage tube blockage because of escharosis, replacement of negative pressure internal sac not standard, loose sealing of the semi-permeable membrane, and the negative pressure tube fell off, compressed or reflexed. The baseline characteristics between the two groups were comparable (P > .05). The incidence of each cause and total incidence of inadequate drainage in INI group were lower than those in RNI group (P < .05, respectively). The incidences of inadequate drainage of all burn sites in INI group were lower than those in RNI group, and the difference of limbs wound between the two group was statistically significant (P < .05). After intervention, the pain intensity of INI group was lower than that of RNI group (P < .05), and the holistic comfort of INI group was higher than that of RNI group (P < .05). The wound healing time and hospital stay time in INI group were lower than those in RNI group, and the total satisfaction rate in INI group was higher than that in RNI group (P < .05, respectively). Applying INI can effectively reduce the incidence of insufficient drainage, reduce pain, improve comfort, shorten wound healing time and hospital stay, and thus improve the overall satisfaction rate of patients, which is worthy of clinical promotion and application.
C1 [Ren, Liqing; Zhang, Cuina; Zhao, Lihua; Li, Cuikun; Zhang, Li; Xue, Xin] Hebei Med Univ, Hosp 1, Dept Burn & Plast Surg, 89 Donggang Rd, Shijiazhuang 050089, Hebei, Peoples R China.
C3 Hebei Medical University
RP Xue, X (通讯作者)，Hebei Med Univ, Hosp 1, Dept Burn & Plast Surg, 89 Donggang Rd, Shijiazhuang 050089, Hebei, Peoples R China.
EM 81017284@qq.com
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NR 22
TC 6
Z9 8
U1 1
U2 14
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2021
VL 18
IS 6
BP 787
EP 795
EA MAR 2021
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA XM0ZU
UT WOS:000630170600001
PM 33738955
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Rashed, A
   Csiszar, M
   Beledi, A
   Gombocz, K
AF Rashed, Aref
   Csiszar, Marton
   Beledi, Agnes
   Gombocz, Karoly
TI The impact of incisional negative pressure wound therapy on the wound
   healing process after midline sternotomy
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE deep sternal wound infections; incisional negative pressure wound
   therapy; inflammatory biomarkers; proliferation phase; wound healing
   process
ID INFECTIONS; PREVENTION; RISK; MEDIASTINITIS; SURGERY
AB Previous studies have reported that the use of incisional negative pressure wound therapy (INPWT) might reduce the incidence of wound infections, although its mechanism remains unknown. We designed a prospective study to explore the effects of INPWT on different stages of the wound healing process. After meeting the inclusion criteria, 108 patients were enrolled. Based on exclusion criteria four patients were excluded and 104 patients were randomised into two groups. INPWT was applied after primary closure of the midline sternotomy in the study group (n = 52), while conventional wound dressing was applied in the control group (n = 52). We documented the incidence of deep sternal wound infections and analysed the pre- and postoperative inflammatory biomarkers and scar size in both groups. No wound infections were observed in the study group compared with six cases (11.1%) in the control group, (P = .026). No significant differences were observed in the inflammatory biomarkers between the groups. Scar size was significantly smaller in the study group. We concluded that INPWT has less effect on the inflammatory phase and appears to have more effect on the proliferation phase through pronounced scar formation.
C1 [Rashed, Aref; Beledi, Agnes; Gombocz, Karoly] Zala Cty St Raphael Hosp, Dept Cardiac Surg, Zrinyi M Str 1, H-8900 Zalaegerszeg, Hungary.
   [Csiszar, Marton] Zala Cty St Raphael Hosp, Dept Radiol, Zalaegerszeg, Hungary.
RP Rashed, A (通讯作者)，Zala Cty St Raphael Hosp, Dept Cardiac Surg, Zrinyi M Str 1, H-8900 Zalaegerszeg, Hungary.
EM aref.rashed.szv@zmkorhaz.hu
RI /AAO-3555-2020
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NR 20
TC 18
Z9 24
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD FEB
PY 2021
VL 18
IS 1
BP 95
EP 102
DI 10.1111/iwj.13497
EA NOV 2020
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA QE1EZ
UT WOS:000591996600001
PM 33236860
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Kaul, P
AF Kaul, Pankaj
TI Sternal reconstruction after post-sternotomy mediastinitis
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Review
DE Deep sternal wound infections; Mediastinitis; Sternal dehiscence;
   Negative pressure wound therapy; Pectoralis major flaps; Rectus
   abdominis flaps; Omental grafts; Latissimus dorsi flaps; Free flaps;
   Allogeneic bone grafts
ID MYOCUTANEOUS ADVANCEMENT FLAPS; OPEN-HEART-SURGERY; VASCULARIZED MUSCLE
   FLAPS; PRESSURE WOUND THERAPY; HIGH-RISK PATIENTS; MEDIAN STERNOTOMY;
   CARDIAC-SURGERY; OMENTAL-FLAP; ANTIBIOTIC-PROPHYLAXIS; CHEST-WALL
AB Background: Deep sternal wound complications are uncommon after cardiac surgery. They comprise sternal dehiscence, deep sternal wound infections and mediastinitis, which will be treated as varying expressions of a singular pathology for reasons explained in the text.
   Methodology and review: This article reviews the definition, prevalence, risk factors, prevention, diagnosis, microbiology and management of deep sternal wound infections and mediastinitis after cardiac surgery. The role of negative pressure wound therapy and initial and delayed surgical management is discussed with special emphasis on plastic techniques with muscle and omental flaps. Recent advances in reconstructive surgery are presented.
   Conclusions: Deep sternal wound complications no longer spell debilitating morbidity and high mortality. Better understanding of risk factors that predispose to deep sternal wound complications and general improvement in theatre protocols for asepsis have dramatically reduced the incidence of deep sternal wound complications. Negative pressure wound therapy and appropriately timed and staged muscle or omental flap reconstruction have transformed the outcomes once these complications occur.
C1 [Kaul, Pankaj] Leeds Gen Infirm, Leeds LS1 3EX, W Yorkshire, England.
   [Kaul, Pankaj] Leeds Gen Infirm, Great George St, Leeds LS1 3EX, W Yorkshire, England.
C3 University of Leeds; Leeds General Infirmary; University of Leeds; Leeds
   General Infirmary
RP Kaul, P (通讯作者)，Leeds Gen Infirm, Great George St, Leeds LS1 3EX, W Yorkshire, England.
EM pankajkaul784@btinternet.com
OI Kaul, Pankaj/0000-0002-5281-2014
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NR 76
TC 71
Z9 98
U1 0
U2 12
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD NOV 2
PY 2017
VL 12
AR 94
DI 10.1186/s13019-017-0656-7
PG 10
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA FL8WD
UT WOS:000414530700001
PM 29096673
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Huang, Y
   Mao, BQ
   Hu, JL
   Xu, B
   Ni, PW
   Hou, LL
   Xie, T
AF Huang, Yao
   Mao, Beiqian
   Hu, Jiale
   Xu, Bing
   Ni, Pengwen
   Hou, Lili
   Xie, Ting
TI Consensus on the health education of home-based negative pressure wound
   therapy for patients with chronic wounds: a modified Delphi study
SO BURNS & TRAUMA
LA English
DT Article
DE Wound healing; Negative pressure wound therapy; Home care services;
   Delphi study; Chronic wound; Self-care
ID CARE; DISCHARGE
AB Background: The study aimed to develop consensus on the components of health education of home-based negative pressure wound therapy (NPWT) for patients with chronic wounds.
   Methods: A Delphi method was used to achieve consensus on the components of health education and 75% agreement and coefficient of variation (CV) <0.25 were used as cutoff. Sixteen experts were recruited purposefully to finish this study.
   Results: Two rounds of consultation were implemented. Consensus was achieved on 36 of the 42 statements. The final agreed list of statements represented three domains: health education before carrying out home-based NPWT, health education for the treatment day of NPWT at hospital and health education for NPWT at home.
   Conclusions: This study was the first attempt to develop consensus on the comprehensive components of health education of home-based NPWT for patients with chronic wounds. According to the established framework and components of health education, wound professionals can safely and effectively implement health education of home-based NPWT for patients with chronic wounds and improve their self-care ability and treatment experience at home.
C1 [Huang, Yao; Mao, Beiqian; Xu, Bing; Ni, Pengwen; Xie, Ting] Shanghai Jiao Tong Univ, Wound Healing Ctr Emergency Dept, Peoples Hosp 9, Sch Med, Shanghai 200011, Peoples R China.
   [Huang, Yao] Shanghai Jiao Tong Univ, Sch Nursing, Shanghai 200025, Peoples R China.
   [Hu, Jiale] Virginia Commonwealth Univ, Dept Nurse Anesthesia, Richmond, VA 23298 USA.
   [Hou, Lili] Shanghai Jiao Tong Univ, Nursing Dept, Sch Med, Peoples Hosp 9, Shanghai 200011, Peoples R China.
C3 Shanghai Jiao Tong University; Shanghai Jiao Tong University; Virginia
   Commonwealth University; Shanghai Jiao Tong University
RP Xie, T (通讯作者)，Shanghai Jiao Tong Univ, Wound Healing Ctr Emergency Dept, Peoples Hosp 9, Sch Med, Shanghai 200011, Peoples R China.; Hou, LL (通讯作者)，Shanghai Jiao Tong Univ, Nursing Dept, Sch Med, Peoples Hosp 9, Shanghai 200011, Peoples R China.
EM houlili1977@hotmail.com; doctortingxie@139.com
RI Hu, Jiale/I-3949-2019
FU Shanghai Jiao Tong University School of Medicine-Nursing research
   project [Jyh1905]; Gaoyuan Nursing Grant Support of Shanghai Municipal
   Education Commission [hlgy1904dxk]; Nursing research project of Ninth
   People's Hospital Affiliated to Shanghai Jiao Tong University School of
   Medicine [JYHL20193D06]; Shanghai 'Rising Stars of Medical Talent' Youth
   Development Nursing Program; Shanghai Nursing Association Young Talent
   Seedling Program
FX The author(s) disclosed receipt of the following financial support for
   the research, authorship and/or publication of this article: this
   program was supported by grants from Shanghai Jiao Tong University
   School of Medicine-Nursing research project (Jyh1905); Gaoyuan Nursing
   Grant Support of Shanghai Municipal Education Commission (hlgy1904dxk);
   Nursing research project of Ninth People's Hospital Affiliated to
   Shanghai Jiao Tong University School of Medicine (JYHL20193D06);
   Shanghai `Rising Stars of Medical Talent' Youth Development Nursing
   Program; Shanghai Nursing Association Young Talent Seedling Program.
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NR 36
TC 11
Z9 14
U1 2
U2 21
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 2321-3868
EI 2321-3876
J9 BURNS TRAUMA
JI Burns Trauma
PY 2021
VL 9
AR tkab046
DI 10.1093/burnst/tkab046
EA DEC 2021
PG 10
WC Emergency Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Emergency Medicine; Dermatology; Surgery
GA YL1VH
UT WOS:000745686300011
PM 34993255
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Shimada, K
   Ojima, Y
   Ida, Y
   Komiya, T
   Matsumura, H
AF Shimada, Kazuki
   Ojima, Yosuke
   Ida, Yukiko
   Komiya, Takako
   Matsumura, Hajime
TI Negative-pressure wound therapy for donor-site closure in radial forearm
   free flap: A systematic review and meta-analysis
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Review
DE donor-site closure; dressing; negative-pressure wound therapy; radial
   forearm free flap; skin graft
ID THICKNESS SKIN-GRAFT; MORBIDITY; RECONSTRUCTION; COMPLICATIONS;
   MANAGEMENT; DRESSINGS; DEFECTS; BOLSTER; DEVICE; HEAD
AB Negative-pressure wound therapy (NPWT) is often used for skin graft site dressing, and several studies have reported that its use improves skin graft failure in the forearm flap donor site. The present systematic review aimed to evaluate the efficacy of NPWT with skin graft for donor-site closure in radial forearm free flap (RFFF) reconstruction. A systematic search in PubMed, Web of Science, and Cochrane Library databases was conducted. The search terms used for PubMed were ([radial forearm]) AND ([donor]) AND ([negative pressure or vacuum]). This review was registered in the International Prospective Register of Systematic Reviews and performed in accordance with the preferred reporting items for systematic reviews and meta-analyses statement. Three prospective randomised controlled trials and three retrospective comparative studies were included. Compared with conventional bolster dressing, the use of NPWT dressing did not lead to significant improvements in partial skin graft loss, tendon exposure, and other complications. NPWT improved hand functionality earlier; nonetheless, the cost of the device and dressings was a disadvantage. The use of NPWT for skin graft fixation in the RFFF donor site is not generally recommended.
C1 [Shimada, Kazuki; Ojima, Yosuke; Ida, Yukiko; Komiya, Takako; Matsumura, Hajime] Tokyo Med Univ, Dept Plast & Reconstruct Surg, Tokyo, Japan.
C3 Tokyo Medical University
RP Matsumura, H (通讯作者)，Tokyo Med Univ, Dept Plast & Reconstruct Surg, Shinjyuku Ku, 6-7-1 Nishishinjyuku, Tokyo 1600023, Japan.
EM hmatsu-tki@umin.ac.jp
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NR 48
TC 20
Z9 23
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD FEB
PY 2022
VL 19
IS 2
BP 316
EP 325
DI 10.1111/iwj.13632
EA JUN 2021
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA YH4HX
UT WOS:000658534900001
PM 34101358
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Muresan, M
   Muresan, S
   Brinzaniuc, K
   Sala, D
   Neagoe, R
AF Muresan, Mircea
   Muresan, Simona
   Brinzaniuc, Klara
   Sala, Daniela
   Neagoe, Radu
TI Negative Pressure Wound Therapy of Open Abdomen and Definitive Closure
   Techniques After Decompressive Laparotomy: A Single-center Observational
   Prospective Study
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE open abdomen; negative pressure wound therapy; abdominal compartment
   syndromey
ID ABDOMINAL COMPARTMENT SYNDROME; TEMPORARY CLOSURE; MANAGEMENT; MESH;
   EXPERIENCE
AB Introduction. Open abdomen is a concept that was developed especially in relation to abdominal compartment syndrome (ACS). Objective. This study presents the evolution and complications related to the management of the open abdomen after decompressive laparotomy, using a standardized method based on negative pressure wound therapy (NPWT). Materials and Methods. This observational prospective study conducted over a 9-month period included 19 patients who underwent decompressive laparotomies for ACS. The triggering conditions were peritonitis, infected and noninfected acute pancreatitis, ileus, and trauma. Temporary abdominal closure was performed using NPWT and the final closure by primary suture or dual mesh. Intra-abdominal pressure was permanently and indirectly monitored transvesically. Results. After decompressive laparotomy, the intra-abdominal pressure decreased significantly (P < .001) compared with the value preoperatively (41.4 mm Hg to 15.3 mm Hg). Mortality was 21.2%, with higher rates for acute pancreatitis (odds ratio [OR] = 3.75) and trauma (OR = 1.25) due to the severity of the primary illness. The final closure was performed after 11.7 days, and primary closure was possible in 4 cases. Conclusions. Decompressive laparotomy significantly reduced intra-abdominal pressure for ACS, improving the prognosis.
C1 [Muresan, Mircea; Muresan, Simona; Brinzaniuc, Klara; Sala, Daniela; Neagoe, Radu] Univ Med & Pharm Tirgu Mures, Targu Mures, Romania.
C3 George Emil Palade University of Medicine, Pharmacy, Science, &
   Technology of Targu Mures
RP Muresan, S (通讯作者)，Univ Med & Pharm Tirgu Mures, Physiol, CR Vivu, D9-19, Targu Mures 540109, Mures, Romania.
EM dr_muremir@yahoo.com
RI Neagoe, Radu Mircea/AAE-6364-2022; Muresan, Mircea/LXV-0408-2024;
   Muresan, Simona/KIG-8771-2024; Sala, Daniela Tatiana/IAM-2498-2023
OI Neagoe, Radu Mircea/0009-0006-0712-6070; Muresan,
   Mircea/0000-0002-5262-8524; 
CR Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
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NR 35
TC 4
Z9 4
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD OCT
PY 2018
VL 30
IS 10
BP 310
EP +
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA IV1TW
UT WOS:000484062600008
PM 30212374
DA 2026-07-24
ER

PT J
AU Campbell, PE
   Smith, GS
   Smith, JM
AF Campbell, Penny E.
   Smith, Gary S.
   Smith, Jennifer M.
TI Retrospective clinical evaluation of gauze-based negative pressure wound
   therapy
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Gauze; Negative pressure wound therapy; Chariker-Jeter
AB Negative pressure wound therapy (NPWT) is an established modality in the treatment of challenging wounds. However, most existing clinical evidence is derived from the use of open-cell polyurethane foam at -125 mmHg. Alternative negative pressure systems are becoming available, which use gauze at a pressure of -80 mmHg. This study describes clinical results from a retrospective non comparative analysis of 30 patients treated with Chariker-Jeter gauze-based negative pressure systems (V1STA (TM), Versatile-1 (TM) and EZ-Care (TM); Smith & Nephew, Inc.) in a long-term care setting. The mean age of the patients was 72 years. The wounds consisted of chronic (n = 11), surgical dehiscence (n = 11) and surgical incision (n = 8). Wound volume and area were recorded at commencement and at the cessation of therapy. Discontinuation of therapy was instigated upon closure through secondary intention or when size and exudate were sufficiently reduced that the wounds could be managed by conventional wound dressing (median 41 days). An overall median reduction in wound volume of 88.0% (P < 0.001) and a 68.0% reduction in area (P < 0.001) compared with baseline were observed over the course of NPWT. The overall rate of volume reduction (15.1% per week) compares favourably with published data from foam-based systems.
C1 [Campbell, Penny E.] Smith & Nephew Inc, Wound Management, Largo, FL 33773 USA.
   [Smith, Gary S.] Smith & Nephew Inc, Stat & Data Management Grp, Kingston Upon Hull, N Humberside, England.
   [Smith, Jennifer M.] Smith & Nephew Inc, NPWT Strateg Business Unit, Kingston Upon Hull, N Humberside, England.
C3 Smith & Nephew; Smith & Nephew; Smith & Nephew
RP Campbell, PE (通讯作者)，Smith & Nephew Wound Management, Negat Pressure Wound Therapy, 11775 Starkey Rd, Largo, FL 33773 USA.
EM penny.campbell@smith-nephew.com
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NR 15
TC 60
Z9 68
U1 0
U2 8
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1742-4801
J9 INT WOUND J
JI Int. Wound J.
PD MAY
PY 2008
VL 5
IS 2
BP 280
EP 286
DI 10.1111/j.1742-481X.2008.00485.x
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA V16AW
UT WOS:000207843500016
PM 18494633
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Liu, Y
   Tang, NN
   Cao, K
   Wang, SH
   Tang, SJ
   Su, HH
   Zhou, JD
AF Liu, Yu
   Tang, Ningning
   Cao, Ke
   Wang, Shaohua
   Tang, Sijie
   Su, Honghui
   Zhou, Jianda
TI Negative-Pressure Wound Therapy Promotes Wound Healing by Enhancing
   Angiogenesis Through Suppression of NLRX1 via miR-195 Upregulation
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE negative-pressure wound therapy; microRNA-195; NLRX1; angiogenesis
ID NF-KAPPA-B; TUMOR ANGIOGENESIS; GROWTH-FACTOR; EXPRESSION; INHIBITION;
   VEGF; CARCINOMA; PATHWAYS; CANCER
AB Negative-pressure wound therapy (NPWT) is one of the most advanced therapeutic methods in the treatment of various hard-to-heal acute and refractory chronic wounds. Recent emerging evidence points to a role of the microRNA-mediated regulation of angiogenesis in ischemic tissues, and a series of microRNAs associated with angiogenesis have been successively identified. In this study, we found that miR-195 expression was significantly upregulated and the microvessel density (MVD) was increased in granulation tissue collected 7 days after NPWT compared with those in the pre-NPWT tissue. Moreover, the expression of NLRX1, the potential target gene of miR-195, was down-regulated in post-NPWT compared with that in pre-NPWT tissue. Significant negative correlations were detected between miR-195 and NLRX1 expression levels (r = -.856, P < .001) and between NLRX1 expression and MVD (r = -.618, P < .05), whereas miR-195 expression was positively correlated with MVD in the granulation tissue (r = .630, P < .05). In summary, NPWT may suppress NLRX1 expression through the upregulation of miR-195 expression, thus efficaciously promoting angiogenesis in the granulation tissue to enhance wound healing.
C1 [Liu, Yu; Tang, Ningning; Cao, Ke; Wang, Shaohua; Su, Honghui; Zhou, Jianda] Cent S Univ, Xiangya Hosp 3, Changsha, Hunan, Peoples R China.
   [Liu, Yu] Inner Mongolia Med Univ, Hohhot, Inner Mongolia, Peoples R China.
   [Tang, Ningning] Xiangya Changde Hosp, Changde, Hunan, Peoples R China.
   [Tang, Sijie] Shantou Univ, Coll Med, Affiliated Hosp 2, Shantou, Guangdong, Peoples R China.
C3 Central South University; Inner Mongolia Medical University; Shantou
   University
RP Zhou, JD (通讯作者)，Cent S Univ, Xiangya Hosp 3, Dept Plast Surg, Changsha, Hunan, Peoples R China.
EM zhoujianda@csu.edu.cn
RI Tang, Ni/Z-5133-2019; Liu, Yu/KRP-3189-2024
OI Liu, Yu/0000-0001-5996-0469
FU National Science Foundation of Hunan Province [2015JJ4053]; Hunan Health
   and Family Planning Commission Research Project [B2016-126, 2015-40];
   Science and Technology Million Project of Inner Mongolia Medical
   University [YKD2017KJBW016]; Inner Mongolia Autonomous Region Natural
   Science Fund [2018BS08009]
FX The author(s) disclosed receipt of the following financial support for
   the research, authorship, and/or publication of this article: (1)
   National Science Foundation of Hunan Province (2015JJ4053); (2) Hunan
   Health and Family Planning Commission Research Project (B2016-126,
   2015-40); (3) Science and Technology Million Project of Inner Mongolia
   Medical University (YKD2017KJBW016); and (4) Inner Mongolia Autonomous
   Region Natural Science Fund (2018BS08009).
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NR 24
TC 16
Z9 21
U1 0
U2 13
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD SEP
PY 2018
VL 17
IS 3
BP 144
EP 150
DI 10.1177/1534734618794856
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA GT6BD
UT WOS:000444594400003
PM 30141361
DA 2026-07-24
ER

PT J
AU Grant-Freemantle, MC
   Ryan, EJ
   Flynn, SO
   Moloney, DP
   Kelly, MA
   Coveney, EI
   O'Daly, BJ
   Quinlan, JF
AF Grant-Freemantle, Marc C.
   Ryan, Eanna J.
   Flynn, Sean O.
   Moloney, Darren P.
   Kelly, Michael A.
   Coveney, Eamonn I.
   O'Daly, Brendan J.
   Quinlan, John F.
TI The Effectiveness of Negative Pressure Wound Therapy Versus Conventional
   Dressing in the Treatment of Open Fractures: A Systematic Review and
   Meta-Analysis
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Review
DE open fractures; negative pressure wound therapy; conventional wound
   dressing; deep infection; fracture nonunion; amputation; flap frequency;
   flap failure; hospital stay; ICU stay
ID INFECTED NONUNION; MANAGEMENT; NPWT
AB Objectives: To compare the efficacy of negative pressure wound therapy (NPWT) versus conventional dressings (CD) in the management of open fractures. Data Sources: A systematic search of English articles in the PubMed/MEDLINE, Embase, and the Cochrane Library through April 2019 comparing NPWT versus CD in the management of open fractures. Study Selection: Inclusion criteria were articles in English language, comparing NPWT with CD in skeletally mature individuals who had sustained an open fracture at any anatomical site, reporting on rates of deep infection, flap frequency, flap failure, nonunion, amputation, length of hospital, or intensive care unit stay. Data Extraction: Two authors independently extracted data from selected studies, and the data collected were compared with verify agreement. Data Synthesis: Pooled odds ratios were calculated for dichotomous outcomes, whereas continuous data were analyzed using the standard weighted mean difference. A random or fixed effect model was used depending on the level of heterogeneity between the studies. Conclusions: NPWT results in decreased likelihood of deep infection and flap failure compared with CD in the management of open fractures not directly amenable to early closure.
C1 [Grant-Freemantle, Marc C.; Flynn, Sean O.; Moloney, Darren P.; Kelly, Michael A.; Coveney, Eamonn I.; O'Daly, Brendan J.; Quinlan, John F.] Tallaght Univ Hosp, Dept Orthopaed, Dublin D24 NR0A, Ireland.
   [Ryan, Eanna J.] Tallaght Univ Hosp, Dept Surg, Dublin, Ireland.
   [O'Daly, Brendan J.; Quinlan, John F.] Royal Coll Surgeons Ireland, Dept Surg, Dublin, Ireland.
   [O'Daly, Brendan J.; Quinlan, John F.] Univ Dublin, Trinity Coll Dublin, Sch Med, Dublin, Ireland.
C3 Royal College of Surgeons in Ireland - RCSI; Trinity College Dublin
RP Grant-Freemantle, MC (通讯作者)，Tallaght Univ Hosp, Dept Orthopaed, Dublin D24 NR0A, Ireland.
EM marcfreemantle@rcsi.ie
RI ; Ryan, Éanna/H-6829-2019; Quinlan, John/AAQ-3286-2021
OI Flynn, Seán/0000-0002-0106-0887; Ryan, Éanna/0000-0003-2609-0836;
   Quinlan, John/0000-0003-3806-415X
CR Arti H, 2016, PAK J MED SCI, V32, P65, DOI 10.12669/pjms.321.8568
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NR 36
TC 24
Z9 31
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD MAY
PY 2020
VL 34
IS 5
BP 223
EP 230
DI 10.1097/BOT.0000000000001750
PG 8
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA NP5OW
UT WOS:000570226500009
PM 32079890
DA 2026-07-24
ER

PT J
AU Liu, XW
   Zhao, Y
   Zhao, FC
   Guo, SL
   Sun, DJ
AF Liu, Xiwen
   Zhao, Yue
   Zhao, Fucheng
   Guo, Suli
   Sun, Daju
TI Surgical treatment of carotid artery stent infection: a case report
SO JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
LA English
DT Article
DE Carotid artery stent infection; vascular graft infection; autologous
   saphenous vein graft revascularization; negative-pressure wound therapy;
   debridement; antibiotic therapy; treatment efficacy
AB The most effective treatment for graft infection is still debated, and the success rate of current treatments is low. We herein report the results of surgical treatment and follow-up of a case of infection acquired during carotid stenting with the aim of exploring the most effective treatments for graft infection. We retrospectively analyzed a patient who was admitted in September 2019. This patient underwent debridement, autologous saphenous vein replacement of the common carotid to internal carotid artery, external carotid artery suturing, and continuous negative-pressure wound therapy for carotid stent infection. Ten days after carotid artery revascularization, the growth of granulation tissue in the incision was good, and we decided to suture the neck incision. Five days after removing the stitches, grade A healing was noted. Furthermore, the carotid artery and autologous vein grafts were unobstructed as shown by carotid artery computed tomography angiography reexamination. The patient was monitored for 8 months with no new neurological symptoms and good healing of the incision. Effective treatment of vascular graft infection includes debridement and removal of the infected graft, autologous vein graft revascularization, and negative-pressure wound therapy combined with antibiotic therapy.
C1 [Liu, Xiwen; Zhao, Yue; Zhao, Fucheng; Guo, Suli; Sun, Daju] Jilin Univ, China Japan Union Hosp, Dept Vasc Surg, 126 Xiantai St, Changchun 130033, Peoples R China.
C3 Jilin University
RP Zhao, Y (通讯作者)，Jilin Univ, China Japan Union Hosp, Dept Vasc Surg, 126 Xiantai St, Changchun 130033, Peoples R China.
EM Z_Yue@jlu.edu.cn
OI Liu, Xiwen/0000-0002-5220-8132
CR Batt M, 2018, ANGIOLOGY, V69, P370, DOI 10.1177/0003319717710114
   Berger P, 2012, J VASC SURG, V56, P714, DOI 10.1016/j.jvs.2012.02.007
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   Swain Timothy W 3rd, 2004, Vasc Endovascular Surg, V38, P75, DOI 10.1177/153857440403800110
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NR 11
TC 0
Z9 0
U1 0
U2 2
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 0300-0605
EI 1473-2300
J9 J INT MED RES
JI J. Int. Med. Res.
PD FEB
PY 2021
VL 49
IS 2
AR 0300060520987081
DI 10.1177/0300060520987081
PG 7
WC Medicine, Research & Experimental; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Pharmacology & Pharmacy
GA QG5NW
UT WOS:000617632800001
PM 33557657
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Deng, K
   Yu, AX
   Xia, CY
   Li, ZH
   Wang, WY
AF Deng, Kai
   Yu, Ai-Xi
   Xia, Cheng-Yan
   Li, Zong-Huan
   Wang, Wei-Yang
TI Combination of negative pressure wound therapy with open bone grafting
   for bone and soft tissue defects
SO MOLECULAR MEDICINE REPORTS
LA English
DT Article
DE negative pressure wound therapy; bone graft; osseous/soft tissue defect;
   polluted wound
AB The aim of this study was to investigate the efficiency of negative pressure wound therapy (NPWT) combined with open bone graft (OBG; NPWT-OBG) for the treatment of bone and soft tissue defects with polluted wounds in an animal model. All rabbits with bone and soft tissue defects and polluted wounds were randomly divided into two groups, the experimental group (NPWT with bone graft) and the control group (OBG). The efficacy of the treatment was assessed by the wound conditions and healing time. Bacterial bioburdens and bony calluses were evaluated by bacteria counting and X-rays, respectively. Furthermore, granulation tissue samples from the wounds on days 0, 3, 7 and 14 of healing were evaluated for blood vessels and vascular endothelial growth factor (VEGF) levels. Wounds in the experimental group tended to have a shorter healing time, healthier wound conditions, lower bacterial bioburden, improvement of the bony calluses and an increased blood supply compared with those in the control group. With NPWT, wound infection was effectively controlled. For wounds with osseous and soft tissue defects, NPWT combined with bone grafting was demonstrated to be more effective than an OBG.
C1 [Deng, Kai; Yu, Ai-Xi; Xia, Cheng-Yan; Li, Zong-Huan; Wang, Wei-Yang] Wuhan Univ, Dept Microorthoped, Zhongnan Hosp, Wuhan 430071, Hubei, Peoples R China.
C3 Wuhan University
RP Yu, AX (通讯作者)，Wuhan Univ, Dept Microorthoped, Zhongnan Hosp, 169 Donghu Rd, Wuhan 430071, Hubei, Peoples R China.
EM yuaixi666@163.com
FU National Natural Science Funds of China [81171713]; National Natural
   Science Funds of Hubei Province [2012FFB04311]
FX This project was supported by the National Natural Science Funds of
   China (grant no. 81171713) and the National Natural Science Funds of
   Hubei Province (grant no. 2012FFB04311).
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NR 21
TC 12
Z9 14
U1 0
U2 10
PU SPANDIDOS PUBL LTD
PI ATHENS
PA POB 18179, ATHENS, 116 10, GREECE
SN 1791-2997
EI 1791-3004
J9 MOL MED REP
JI Mol. Med. Rep.
PD AUG
PY 2013
VL 8
IS 2
BP 468
EP 472
DI 10.3892/mmr.2013.1536
PG 5
WC Oncology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Research & Experimental Medicine
GA 190XS
UT WOS:000322377400025
PM 23784004
OA Bronze
DA 2026-07-24
ER

PT J
AU Kondor, AE
   Baracs, J
   Varga, P
   Gowda, YS
   Garcia, E
   Halvax, P
   Vereczkei, A
AF Kondor, Ariella Edina
   Baracs, Jozsef
   Varga, Peter
   Gowda, Yashwanth Sudhendra
   Garcia, Elisabeth
   Halvax, Peter
   Vereczkei, Andras
TI Negative Pressure Wound Therapy for Complex Perianal Fistulas: A Case
   Series
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE colorectal surgery; negative pressure wound therapy; perianal fistula;
   wound healing
AB Complex perianal fistulas are difficult to treat because of high recurrence rates and the need to preserve sphincter function. Negative pressure wound therapy (NPWT) improves healing in complex wounds, but its role in perianal fistula surgery is not well defined. This case series evaluated the feasibility, safety and early clinical outcomes of NPWT following surgical excision of complex perianal fistula tracts. A retrospective case series was conducted including eight adults with high or otherwise complex cryptoglandular perianal fistulas treated by surgical debridement followed by portable NPWT. Outcomes assessed were time to epithelialisation, symptom resolution, recurrence, complications and NPWT-related technical issues and refinements. Seven of eight patients achieved complete epithelialisation of the perianal wound after NPWT. One patient developed recurrence and required ongoing seton drainage. Over the course of the series, optimisation of sealing, sponge contouring and use of a bridge technique improved dressing reliability and wound progression. No NPWT device-related adverse events were observed. NPWT appears to be a feasible, well tolerated adjunct to surgery for complex cryptoglandular perianal fistulas, with high early healing rates and no device complications in this small series. Larger prospective studies are warranted to confirm efficacy and define optimal technical parameters.
C1 [Kondor, Ariella Edina; Baracs, Jozsef; Varga, Peter; Gowda, Yashwanth Sudhendra; Garcia, Elisabeth; Halvax, Peter; Vereczkei, Andras] Univ Pecs, Med Sch, Dept Surg, Pecs, Hungary.
C3 University of Pecs
RP Kondor, AE (通讯作者)，Univ Pecs, Med Sch, Dept Surg, Pecs, Hungary.
EM kondor.ariella@pte.hu
RI Vereczkei, Andras/AAI-7089-2020
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NR 18
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR 26
PY 2026
VL 23
IS 5
AR e70920
DI 10.1111/iwj.70920
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA GZ0BM
UT WOS:001748409100001
PM 42036402
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Nolff, MC
AF Nolff, Mirja C.
TI Filling the vacuum: Role of negative pressure wound therapy in open
   wound management in cats
SO JOURNAL OF FELINE MEDICINE AND SURGERY
LA English
DT Review
DE Open wound treatment; cat wound healing; skin grafts; negative pressure
   wound therapy
ID THICKNESS SKIN-GRAFTS; COATED FOAM DRESSINGS; ASSISTED CLOSURE;
   RETROSPECTIVE EVALUATION; CHLORHEXIDINE DIACETATE; DOGS; GRANULATION;
   REPAIR; MECHANISM; RESPONSES
AB Practical relevance: Open wounds and their treatment present a common challenge in veterinary practice. Approaching 15 years ago negative pressure wound therapy (NPWT) started to be incorporated into clinical veterinary medicine, and its availability is becoming more widespread in Europe and the USA. Use of this therapy has the potential to significantly increase the healing rate of open wounds as well as free skin grafts in small animals, and it has been occasionally described for the management of feline wounds. Aim: This review describes the mechanisms of action of, and indications for, NPWT, and offers recommendations for NPWT specific to feline patients. Evidence base: The information presented is based on the current evidence and the author's clinical experience of the technique gained over the past 12 years. Comparative studies of different treatment options are lacking and, since wound healing in cats and dogs differs, cat-specific studies are especially needed. Well-designed wound healing studies comparing different advanced techniques will improve open wound healing in cats in the future, and potentially allow better understanding of the role of NPWT in this setting.
C1 [Nolff, Mirja C.] Univ Zurich, Tierspital Zurich, Clin Small Anim Surg, Winterthurerstr 260, CH-8057 Zurich, Switzerland.
C3 University of Zurich
RP Nolff, MC (通讯作者)，Univ Zurich, Tierspital Zurich, Clin Small Anim Surg, Winterthurerstr 260, CH-8057 Zurich, Switzerland.
EM mirjachristine.nolff@uzh.ch
RI Nolff, Mirja/W-6756-2019
OI Nolff, Mirja/0000-0001-9317-7769
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NR 72
TC 7
Z9 10
U1 0
U2 12
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1098-612X
EI 1532-2750
J9 J FELINE MED SURG
JI J. Feline Med. Surg.
PD SEP
PY 2021
VL 23
IS 9
BP 823
EP 833
DI 10.1177/1098612X211037873
PG 11
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA UF4ER
UT WOS:000688528700002
PM 34428942
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Hu, J
   Fu, SZ
AF Hu, Jing
   Fu, Shouzhi
TI The perioperative nursing effect of VSD closed negative pressure
   drainage in the treatment of emergency traumatic wound infection
SO MEDICINE
LA English
DT Article
DE emergency trauma; perioperative period; vacuum sealing drainage closed
   negative pressure; wound infection
ID SEALING DRAINAGE
AB This study aims to explore the perioperative nursing effect of vacuum sealing drainage closed negative pressure drainage in the treatment of emergency traumatic wound infection. A total of 116 patients with trauma-related wound infection were admitted to the Department of orthopedics and skin wound at our hospital from April 2021 to October 2022 were selected as the study subjects. They were divided into an observation group and a control group, with 58 patients in each group. Patients in the control group received traditional wound debridement, while patients in the observation group underwent debridement with the addition of vacuum-sealed drainage closed negative pressure. The treatment outcomes, pain levels, various treatment indicators, and wound healing conditions of the 2 groups were compared. The overall effective rate of treatment in the observation group was 93.10%, which was significantly higher than the control group's rate of 75.86% (P < .05). The Visual Analog Scale scores of patients in both groups were compared at 1 hour after treatment and 6 hours after treatment (P > .05). However, at 12 hours and 24 hours after treatment, the Visual Analog Scale scores of patients in the observation group were significantly lower than those in the control group (P < .05). The observation group of patients had fewer changes of dressings after treatment compared to the control group (P < .05). The wound healing time, antibiotic usage duration, and hospitalization time were all shorter in the observation group than in the control group (P < .05). The Bates-Jensen scores of both groups of patients before treatment were compared (P > .05). After treatment, the Bates-Jensen scores in both groups decreased, and the observation group had lower scores than the control group (P < .05). The use of vacuum sealing drainage closure therapy in patients with emergency trauma-related wound infections can alleviate pain, reduce the frequency of dressing changes, accelerate wound healing, and improve wound healing outcomes. It is worthy of clinical promotion.
C1 [Hu, Jing; Fu, Shouzhi] Wuhan Univ, Wuhan Hosp 3, Dept ICU Emergency, Wuhan 430074, Hubei, Peoples R China.
C3 Wuhan University
RP Fu, SZ (通讯作者)，Wuhan Univ, Wuhan Hosp 3, Dept ICU Emergency, Wuhan 430074, Hubei, Peoples R China.
EM 861644139@qq.com; hjing202409@163.com
CR Alnakshabandie WMY, 2023, J INFECT DEV COUNTR, V17, P525, DOI 10.3855/jidc.17554
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NR 20
TC 2
Z9 3
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD NOV 8
PY 2024
VL 103
IS 45
AR e40376
DI 10.1097/MD.0000000000040376
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA L7Q4L
UT WOS:001352625300021
PM 39533567
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Tu, KK
   Li, H
   Bai, BL
   Weng, SJ
   Wu, ZY
   Boodhun, V
   Feng, ZH
   Cheng, L
   Yang, L
AF Tu, Kai-Kai
   Li, Hang
   Bai, Bing-Li
   Weng, She-Ji
   Wu, Zong-Yi
   Boodhun, Viraj
   Feng, Zhen-Hua
   Cheng, Liang
   Yang, Lei
TI Intra- and extramedullary fixation combined with vacuum sealing drainage
   for selective treatment of open tibial fractures: a retrospective case
   series
SO INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
LA English
DT Article
DE Titanium elastic nails; external fixator; open tibial fractures; vacuum
   sealing drainage
ID PRESSURE WOUND THERAPY; ILIZAROV EXTERNAL FIXATION; PLATE
   OSTEOSYNTHESIS; RANDOMIZED-TRIAL; DISTAL TIBIA; MANAGEMENT; BONE;
   DIAPHYSEAL; CLOSURE; FEMUR
AB The objective of this study was to introduce a novel method of percutaneous titanium elastic nails augmented by unilateral external fixator (BioEF-TENs system) combined with vacuum sealing drainage (VSD) technique and evaluate the effects in the management of open fractures of tibia. From January 2011 to June 2013, 15 patients (11M/4F) with a mean age of 41.6 years (16-60 years) were treated with this method. According to the Anderson-Gustilo classification, there were 3 cases defined as Gustilo I, 5 as Gustilo II, 3 as Gustilo IIIA, 2 as Gustilo IIIB and 2 as Gustilo IIIC. Follow-up was done at 1, 2, 3 months postoperatively, and then at 2 months intervals, to conduct clinical and radiographic examinations. The mean follow-up period of 15 patients was 18 months. After the VSD was removed, 3 patients needed skin-grafting and 2 case needed flap coverage. The external fixator was removed with a mean time of 23.3 weeks (18-45 weeks), the average union time is 29.8 weeks (21-56 weeks). Delayed union was observed in 3 patients and there was no case with mal-union. There were 3 cases with pin track infection which were treated after external fixator removal. Superficial wound infection was existed in one patient and was cured by intravenous sensitive antibiotics and VSD. No case was observed with decrease ROM or pain of the knee. And only one patient's ankle joint range of movement (ROM) was decreased by 20-25%. The results indicated that the BioEF-TENs system combined with VSD can achieve bone stability at one stage fixation operation, which not only avoids converting fixation but also obtains effective soft tissue protection, which is a novel technique for open fractures of tibia with certain indications and worthy for further research.
C1 [Tu, Kai-Kai] Xiaoshan Tradit Chinese Med Hosp, Dept Orthoped Surg, Hangzhou, Zhejiang, Peoples R China.
   [Li, Hang; Bai, Bing-Li; Weng, She-Ji; Wu, Zong-Yi; Boodhun, Viraj; Feng, Zhen-Hua; Cheng, Liang; Yang, Lei] Wenzhou Med Univ, Dept Orthopaed Surg, Affiliated Hosp 2, Wenzhou, Zhejiang, Peoples R China.
   [Li, Hang; Bai, Bing-Li; Weng, She-Ji; Wu, Zong-Yi; Boodhun, Viraj; Feng, Zhen-Hua; Cheng, Liang; Yang, Lei] Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou, Zhejiang, Peoples R China.
C3 Wenzhou Medical University; Wenzhou Medical University
RP Yang, L (通讯作者)，Wenzhou Med Univ, Dept Orthopaed Surg, Affiliated Hosp 2, Wenzhou, Zhejiang, Peoples R China.; Yang, L (通讯作者)，Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou, Zhejiang, Peoples R China.
EM lihtc@163.com
CR [Anonymous], PERCUTANEOUS MINIMAL
   [Anonymous], ZHEJIANG MED J
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NR 32
TC 1
Z9 1
U1 0
U2 3
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1940-5901
J9 INT J CLIN EXP MED
JI Int. J. Clin. Exp. Med.
PY 2018
VL 11
IS 3
BP 2248
EP 2255
PG 8
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA GB4BZ
UT WOS:000429006600094
DA 2026-07-24
ER

PT J
AU Özer, MT
   Sinan, H
   Sapmaz, E
   Gürkok, S
   Kaymak, S
   Kozak, O
AF Ozer, Mustafa Tahir
   Sinan, Huseyin
   Sapmaz, Ersin
   Gurkok, Sedat
   Kaymak, Sahin
   Kozak, Orhan
TI Negative pressure wound closure system for giant thoracic defect closure
   in a patient with completely visible pericardium: A case report
SO TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND
   CARDIOVASCULAR SURGERY
LA English
DT Article
DE Negative pressure wound therapies; vacuum assisted closure; wound care
ID VACUUM-ASSISTED CLOSURE; MANAGEMENT; THERAPY
AB Negative pressure wound closure system facilitates wound closure via wound contraction. In this article, we report a successful application of thoracic negative pressure wound closure system to fill the thoracic defect, control infection, and expand the lung in a 35-year-old male patient with three-rib defect, lung parenchyma injury, empyema, left complete pneumothorax, and visible pericardium after gunshot injury. The excellent result obtained in our patient demonstrates that negative pressure wound closure system is a good choice for treating high-energy thoracic injuries by reducing wound infection and enabling early wound closure.
C1 [Ozer, Mustafa Tahir; Kaymak, Sahin] Univ Hlth Sci, Gulhane Training & Res Hosp, Dept War Surg, Ankara, Turkey.
   [Sinan, Huseyin; Kozak, Orhan] Univ Hlth Sci, Gulhane Training & Res Hosp, Dept Gen Surg, Ankara, Turkey.
   [Sapmaz, Ersin; Gurkok, Sedat] Univ Hlth Sci, Gulhane Training & Res Hosp, Dept Thorac Surg, Ankara, Turkey.
C3 University of Health Sciences Turkey; Gulhane Training & Research
   Hospital; University of Health Sciences Turkey; Gulhane Training &
   Research Hospital; University of Health Sciences Turkey; Gulhane
   Training & Research Hospital
RP Sinan, H (通讯作者)，Gulhane Egitim & Arastirma Hastanesi, Genel Cerrahi Klin, TR-06010 Ankara, Turkey.
EM huseyinsinan@gmail.com
RI ; Sapmaz, Ersin/G-1398-2015; KAYMAK, SAHIN/QOB-0010-2026
OI Kozak, Orhan/0000-0002-7302-1203; Kaymak, Şahin/0000-0003-4717-5791; 
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Begum SSS, 2012, ANN THORAC SURG, V94, P1835, DOI 10.1016/j.athoracsur.2012.08.009
   Demir A., 2006, TURK PLAST REKONSTR, V14, P171
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
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   Labler L, 2002, Swiss Surg, V8, P266, DOI 10.1024/1023-9332.8.6.266
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   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Ozer MT, 2011, INT WOUND J, V8, P599, DOI 10.1111/j.1742-481X.2011.00835.x
   Ozturk E, 2009, AM J SURG, V197, P660, DOI 10.1016/j.amjsurg.2008.04.018
   Rocco G, 2012, EUR J CARDIO-THORAC, V41, P1069, DOI 10.1093/ejcts/ezr196
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   Stuhmiller J.H., 1991, PHYS MECH PRIMARY BL, p241 270
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NR 16
TC 0
Z9 0
U1 0
U2 5
PU BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK
PI ATASEHIR
PA ORNEK MH DR SUPHI EZGI SK SARAY APT NO 11 D 6, ATASEHIR, ISTANBUL 34704,
   TURKEY
SN 1301-5680
J9 TURK GOGUS KALP DAMA
JI Turk Gogus Kalp Damar Cerrahisi Derg.
PD OCT
PY 2018
VL 26
IS 4
BP 668
EP 672
DI 10.5606/tgkdc.dergisi.2018.15703
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HB3AC
UT WOS:000450917400024
PM 32082815
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Griffin, L
   Sifuentes, MM
AF Griffin, Leah
   Sifuentes, Mikaela M.
TI Retrospective Payor Claims Analysis of Patients Receiving Outpatient
   Negative Pressure Wound Therapy With Remote Therapy Monitoring
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE negative pressure wound therapy; telemedicine; remote consultation; cost
   savings; patient compliance; outpatients; wound healing
ID ADHERENCE
AB Introduction. Patient nonadherence to home care treatment poses an obstacle to wound healing that can lead to additional costs and prolong care. Objective. This retrospective pilot study examines the potential time and cost savings associated with a remote therapy monitoring (RTM) program designed to improve negative pressure wound therapy (NPWT) adherence in the home care setting. Materials and Methods. Payor claims data of patients receiving NPWT with (n = 199) or without (n = 232) RTM between January 1 and June 30, 2017 were analyzed. Results. The RTM patients were significantly older (P = .0401), had a higher percentage of Medicare Advantage plans (P = .0015), and had a higher mean Charleston Comorbidity Index score (P = .0115) than non-RTM patients. For both groups, chronic wounds had higher 90-day wound-related costs than acute wounds. The median length of treatment for RTM patients was shorter than non-RTM patients (P = .0394). Mean 90-day wound-related costs for RTM and non-RTM patients were $10 515 and $12 158, respectively. Conclusions. These results build upon previous studies of RTM-assisted outpatient NPWT and suggest an opportunity for wound care cost savings.
C1 [Griffin, Leah; Sifuentes, Mikaela M.] Acelity, 12930 W Interstate 10, San Antonio, TX 78249 USA.
RP Griffin, L (通讯作者)，Acelity, 12930 W Interstate 10, San Antonio, TX 78249 USA.
EM Leah.Griffin@Acelity.com
RI Sifuentes, Mikaela/AAJ-1776-2021
OI Sifuentes, Mikaela/0000-0002-7914-4183
CR Griffin L, 2018, WOUNDS, V30, pE81
   Viswanathan M, 2012, ANN INTERN MED, V157, P785, DOI 10.7326/0003-4819-157-11-201212040-00538
NR 2
TC 4
Z9 5
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD FEB
PY 2019
VL 31
IS 2
BP E9
EP E11
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA IV4ZZ
UT WOS:000484282300003
PM 30730299
DA 2026-07-24
ER

PT J
AU Hu, J
   Yan, JW
   Su, YX
AF Hu, Jie
   Yan, Jingwen
   Su, Yuxi
TI Mini approaches fasciotomy combined with vacuum sealing drainage for
   acute compartment syndrome caused by fractures in children
SO INTERNATIONAL ORTHOPAEDICS
LA English
DT Article
DE Fasciotomy; Acute compartment syndrome; Mini approaches; Orthopedic;
   Vacuum sealing drainage
ID LEG; DIAGNOSIS
AB PurposeAcute compartment syndrome (ACS) is an urgent, critical condition that requires immediate fasciotomy once diagnosed. Traditionally, fasciotomy of the forearms and lower leg involves one or two long approaches. Our previous study demonstrated that mini approaches fasciotomy was an effective method to treat ACS. This study is aimed at further evaluating the limb functions and complications of mini approaches combined with vacuum sealing drainage (VSD) for treating ACS caused by fractures in the forearms and lower legs.MethodsThis was a retrospective cross-sectional study, and after applying the inclusion and exclusion criteria, we reviewed 126 children who underwent mini treatment approaches for ACS from Jan 2008 to Jan 2022. The selected patients were divided into two groups: group A (ACS group; 58 patients aged 7.77 & PLUSMN;3.45 years) and group B (ACS combined with VSD; 68 patients aged 7.17 & PLUSMN;3.55 years). Patients' clinical data were collected. The patients were followed up, and muscle function in the forearms and lower legs was evaluated.ResultsThe overall incidence of lower legs and forearms ACS was 126/29642 (0.425%). The most common mechanisms of injury were fractures of the forearm (39/74, 52.7%), supracondylar humerus (31/74 41.9%), and elbow (4/74, 5.4%), while those for the lower legs were fractures of the proximal tibia (19/52, 36.5%), midshaft of tibia (25/52, 48.1%), and distal tibia (7/52, 13.5%). According to Flynn's assessment, no significant difference was observed between the two groups (p=0.151). However, the two groups showed significant differences in the hospitalization time (p=0.002) and incision infection rate (0.043).ConclusionsMini approaches fasciotomy combined with VSD is an effective and safe method to treat ACS of the forearms and lower legs caused by fractures in children. This method involves a single-stage surgery and is associated with shorter hospitalization time and incision infection.
C1 [Hu, Jie; Yan, Jingwen; Su, Yuxi] Chongqing Med Univ, Orthoped Dept, Childrens Hosp, Chongqing, Peoples R China.
   [Hu, Jie; Yan, Jingwen; Su, Yuxi] Chongqing Key Lab Pediat, Chongqing, Peoples R China.
   [Hu, Jie; Yan, Jingwen; Su, Yuxi] Minist Educ, Key Lab Child Dev & Disorders, Chongqing, Peoples R China.
   [Hu, Jie; Yan, Jingwen; Su, Yuxi] Natl Clin Res Ctr Child Hlth & Disorders, Chongqing, Peoples R China.
   [Hu, Jie; Yan, Jingwen; Su, Yuxi] China Int Sci & Technol Cooperat Base Child Dev &, Chongqing, Peoples R China.
   [Hu, Jie; Yan, Jingwen; Su, Yuxi] Chongqing Med Univ, Jiangxi Hosp, Affiliated Childrens Hosp, Nanchang, Peoples R China.
   [Hu, Jie] Chengdu Womens & Childrens Cent Hosp, Orthoped Dept, Chengdu, Sichuan, Peoples R China.
   [Yan, Jingwen] Cent South Univ, Dept Clin Med, Xiangya Sch Med, Changsha, Peoples R China.
C3 Chongqing Medical University; Chongqing Medical University; Central
   South University
RP Su, YX (通讯作者)，Chongqing Med Univ, Orthoped Dept, Childrens Hosp, Chongqing, Peoples R China.; Su, YX (通讯作者)，Chongqing Key Lab Pediat, Chongqing, Peoples R China.; Su, YX (通讯作者)，Minist Educ, Key Lab Child Dev & Disorders, Chongqing, Peoples R China.; Su, YX (通讯作者)，Natl Clin Res Ctr Child Hlth & Disorders, Chongqing, Peoples R China.; Su, YX (通讯作者)，China Int Sci & Technol Cooperat Base Child Dev &, Chongqing, Peoples R China.; Su, YX (通讯作者)，Chongqing Med Univ, Jiangxi Hosp, Affiliated Childrens Hosp, Nanchang, Peoples R China.
EM 981341831@qq.com; 2737572854@qq.com; suyuxi@hospital.cqmu.edu.cn
RI Su, Yuxi/KEI-4480-2024
OI Su, Yuxi/0000-0003-1904-5594
FU Thanks are due to Hanjun Wu in our Medical Record Department for data
   collection and all staffs in Orthopedic Department performing the
   surgeries.
FX Thanks are due to Hanjun Wu in our Medical Record Department for data
   collection and all staffs in Orthopedic Department performing the
   surgeries.
CR Bible JE, 2013, J ORTHOP TRAUMA, V27, P607, DOI 10.1097/BOT.0b013e318291f284
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   Zhang L, 2020, EXP THER MED, V20, P2305, DOI 10.3892/etm.2020.8941
NR 21
TC 2
Z9 2
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0341-2695
EI 1432-5195
J9 INT ORTHOP
JI Int. Orthop.
PD JUN
PY 2024
VL 48
IS 6
SI SI
BP 1481
EP 1487
DI 10.1007/s00264-023-05984-7
EA SEP 2023
PG 7
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA PQ8Z5
UT WOS:001068133300001
PM 37733064
DA 2026-07-24
ER

PT J
AU Li, RG
   Yu, B
   Wang, G
   Chen, B
   Qin, CH
   Guo, G
   Jin, D
   Ren, GH
AF Li, Run-Guang
   Yu, Bin
   Wang, Gang
   Chen, Bin
   Qin, Cheng-He
   Guo, Gang
   Jin, Dan
   Ren, Gao-Hong
TI Sequential therapy of vacuum sealing drainage and free-flap
   transplantation for children with extensive soft-tissue defects below
   the knee in the extremities
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Article
DE Free flap; Transplantation; Vacuum sealing drainage (VSD) technique;
   Microsurgical technique
ID PRESSURE WOUND THERAPY; CROSS-LEG FLAP; ASSISTED CLOSURE;
   RECONSTRUCTION; TRAUMA; INJURIES; FOOT
AB Purpose: The aim of the study is to evaluate the surgical technique and clinical significance of the sequential therapy of vacuum sealing drainage (VSD) and free-flap transplantation for children with extensive soft-tissue defects below the knee in the extremities.
   Methods: Twenty-two children (aged from 3 to 10 years) received sequential therapy of VSD and free-flap transplantation. All cases suffered from extensive area soft-tissue defects and exposure or partial defects of bones, tendons and other deep tissues. The wound sizes varied from 10 cm x 6 cm to 30 cm x 22 cm. Amongst 22 cases, 12 cases had fresh wounds and the remaining 10 children had necrotising infection. After complete debridement, the wounds were covered by VSD. External fixation or Kirschner-wire fixation should be performed for the cases complicated by unsteady fractures. After the removal of negative pressure VSD devices, free-flap transplantations were performed in 8 cases after debridement, and 14 cases received combined therapy of free-flap transplantation and skin grafting depending upon the severity of soft-tissue and deep-tissue defects. The flap survival and wound healing were followed up postoperatively.
   Results: After VSD treatment, the infection of deep-tissue exposure was effectively prevented, and granulation tissues surrounding the exposed areas of tendons and bones grew well. All patients who received free-flap transplantation at the second stage survived without the occurrence of vascular crisis, infection or sinus formation. During follow-up ranging from 6 to 24 months, all the patients were satisfied with the morphological appearance and functional recovery of the affected limbs.
   Conclusion: Sequential therapy of VSD and free-flap transplantation can serve as a reliable option for children with extensive soft-tissue defects below the knee in the extremities and exposed deep tissues, after complete debridement, which significantly shortens remedy period, enhances success rate for surgery and achieves maximal restoration of limb function. (C) 2011 Elsevier Ltd. All rights reserved.
C1 [Li, Run-Guang; Yu, Bin; Wang, Gang; Chen, Bin; Qin, Cheng-He; Guo, Gang; Jin, Dan; Ren, Gao-Hong] So Med Univ, Dept Orthopaed & Traumatol, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R China.
C3 Southern Medical University - China
RP Ren, GH (通讯作者)，So Med Univ, Dept Orthopaed & Traumatol, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R China.
EM doctor020@163.com
OI Gaohong, Ren/0000-0002-4941-6723; Runguang, Li/0000-0002-4703-7180
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NR 30
TC 36
Z9 65
U1 0
U2 22
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0020-1383
EI 1879-0267
J9 INJURY
JI Injury-Int. J. Care Inj.
PD JUN
PY 2012
VL 43
IS 6
BP 822
EP 828
DI 10.1016/j.injury.2011.09.031
PG 7
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA 942LI
UT WOS:000304045100025
PM 22071284
DA 2026-07-24
ER

PT J
AU James, K
   Glasswell, A
   Costa, B
AF James, Kelly
   Glasswell, Amy
   Costa, Ben
TI Single-use negative pressure wound therapy versus conventional dressings
   for the reduction of surgical site infections in closed surgical
   incisions: Systematic literature review and meta-analysis
SO AMERICAN JOURNAL OF SURGERY
LA English
DT Review
DE Surgical site infection; Surgical site complication; General surgery;
   Single-use negative pressure wound therapy; Systematic literature
   review; Meta-analysis
ID CARE-ASSOCIATED INFECTIONS; RISK-FACTORS; PRIMARY HIP; SURGERY;
   PREVENTION; COSTS; TRIAL; ARTHROPLASTY; FRACTURES; CLOSURE
AB Background: To evaluate whether a single -use negative pressure wound therapy (sNPWT) device can reduce the incidence of surgical site infection (SSI) in at -risk patients with closed surgical incisions across a range of surgical specialties, compared with standard care. Methods: PubMed, Embase, Cochrane Library and ClinicalTrials.gov were searched from the period January 2011 to April 2021. Results: Out of 15,283 articles identified, 19 were included. A statistically significant improvement (p < 0.05) in the composite SSI (odds ratio [OR]: 0.36; 95 % confidence interval [CI]: 0.27-0.49), superficial SSI (OR: 0.30; 95 % CI: 0.17-0.53), and deep SSI (OR: 0.67; 95 % CI: 0.46-0.96) outcomes was observed with the sNPWT device compared with standard care in a pooled analysis of all surgical specialties. Conclusion: A -80 mmHg sNPWT device reduces the incidence of composite, superficial, and deep SSIs when compared with standard care across a heterogenous at -risk surgical population containing a variety of surgical specialties.
C1 [James, Kelly] United Surg Associates Kansas City, Gen Surg, Independence, MO USA.
   [Glasswell, Amy; Costa, Ben] Smith & Nephew, Global Clin & Med Affairs, Kingston Upon Hull, England.
   [Costa, Ben] Smith & Nephew, Global Clin & Med Affairs, 101 Hessle Rd, Kingston Upon Hull HU3 2BN, England.
C3 Smith & Nephew; Smith & Nephew
RP Costa, B (通讯作者)，Smith & Nephew, Global Clin & Med Affairs, 101 Hessle Rd, Kingston Upon Hull HU3 2BN, England.
EM onesurgn@yahoo.com; Amy.Glasswell@smith-nephew.com;
   Ben.Costa@smith-nephew.com
OI Glasswell, Amy/0000-0001-9158-5427; Costa, Benedict/0000-0002-7132-2520
FU Smith and Nephew Inc.
FX Funding This work was supported by Smith and Nephew Inc.
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NR 47
TC 14
Z9 16
U1 0
U2 2
PU EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
PI BRIDGEWATER
PA 685 ROUTE 202-206 STE 3, BRIDGEWATER, NJ 08807 USA
SN 0002-9610
EI 1879-1883
J9 AM J SURG
JI Am. J. Surg.
PD FEB
PY 2024
VL 228
BP 70
EP 77
DI 10.1016/j.amjsurg.2023.10.031
EA FEB 2024
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA NB8N5
UT WOS:001198076500001
PM 37903665
OA hybrid
DA 2026-07-24
ER

PT J
AU Loney, A
   Diaz-Garcia, RJ
   Murdoch, JM
   Spitzer, M
AF Loney, Amanda
   Diaz-Garcia, Rafael J.
   Murdoch, Julie M.
   Spitzer, Mandy
TI Utilizing International Consensus Panel Recommendations and a Clinical
   Decision Tree to Guide Selection of Negative Pressure Wound Therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE acute wounds; chronic wounds; economic efficiencies; quality of life;
   traditional negative pressure wound therapy; single-use negative
   pressure wound therapy
ID COST
AB Introduction. A variety of NPWT products have become commercially available in the last 30 years. Utilizing advanced wound therapies appropriately can improve patient outcomes and decrease health care expenditures. Due to the increasing number of available product options, Hurd and colleagues published 10 Consensus Statements and a clinical decision tree to provide guidance on how and when to use NPWT and when to transition between device types. Objective. To demonstrate the applicability of the consensus panel's statements and the clinical decision tree, 2 clinicians in the United States and Canada explored the benefits of applying these recommendations into their routine wound management practice. Materials and Methods. Case studies were collected and reviewed in accordance with the Consensus Statements and clinical decision tree. Results. Case presentations illustrate the application of the consensus panel's guidance through the prescribing of the NPWT products utilized as standard of care within both facilities. Conclusion. Utilizing NPWT devices according to the consensus panel recommendations and the clinical decision tree may assist in optimizing care delivery to patients and address logistical and economic efficiencies.
C1 [Loney, Amanda] Bayshore Home Hlth, Hamilton, ON, Canada.
   [Diaz-Garcia, Rafael J.] Allegheny Hlth Network, Supply Chain & GPO, Pittsburgh, PA USA.
   [Murdoch, Julie M.] Global Clin & Med Affairs Smith & Nephew, Watford, England.
   [Spitzer, Mandy] Global Clin & Med Affairs Smith & Nephew, Ft Worth, TX USA.
C3 Allegheny Health Network
RP Spitzer, M (通讯作者)，Global Clin & Med Affairs Smith & Nephew, 5600 Clearfork Main St, Ft Worth, TX 76109 USA.
EM amanda.spitzer@smith-nephew.com
RI Diaz-Garcia, Rafael/JGD-0932-2023
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NR 17
TC 4
Z9 4
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUL
PY 2023
VL 35
IS 7
BP E209
EP E217
DI 10.25270/wnds/22085
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA S5NA2
UT WOS:001071620200002
PM 37523737
DA 2026-07-24
ER

PT J
AU Phiri, CC
   Valle, C
   Botzheim, J
   Ju, ZJ
   Liu, HH
AF Phiri, Charles C.
   Valle, Cristina
   Botzheim, Janos
   Ju, Zhaojie
   Liu, Honghai
TI Fuzzy rule-based model for outlier detection in a Topical Negative
   Pressure Wound Therapy Device
SO ISA TRANSACTIONS
LA English
DT Article
DE Topical Negative Pressure Wound Therapy; Device; Outlier detection;
   Fuzzy rule-based model; Bacterial Memetic Algorithm
ID MEMBERSHIP FUNCTIONS; PARAMETERS; ALGORITHM
AB This paper proposes a novel method for offline outlier detection in nonlinear dynamical systems using an input-output dataset of a Topical Negative Pressure Wound Therapy Device, NPWT. The fundamental characteristics of an NPWT describe a chaotic system whose states vary over time and may result in unpredictable and possibly anomalous divergent behavior in the presence of perturbations and other unmodeled system dynamics, despite a quasi-stable controller. Bacterial Memetic Algorithm, BMA, is used to generate fuzzy rule-based models of the input-output dataset. The error definition in the fuzzy rule extraction features a novel application of the Canberra Distance. The optimal number of rules for identifying the outliers, validated against both artificial and real system datasets, is calculated from the sample of inferred fuzzy models. The optimal number of rules is two in both cases based on the maximum average-error-drop. Using three or more rules results in better error performance; however, the algorithm learns the nuances of the outlier patterns instead. Novel methods for creating the outlier list and determining the optimal number of rules for the outlier detection problem are proposed. (C) 2021 ISA. Published by Elsevier Ltd. All rights reserved.
C1 [Phiri, Charles C.; Valle, Cristina] CC Initiat Ltd, Andover, Hants, England.
   [Phiri, Charles C.; Ju, Zhaojie; Liu, Honghai] Univ Portsmouth, Sch Comp, Portsmouth, Hants, England.
   [Valle, Cristina] Tokyo Metropolitan Univ, Tokyo, Japan.
   [Botzheim, Janos] Budapest Univ Technol & Econ, Fac Mech Engn, Dept Mechatron Opt & Mech Engn Informat, Budapest, Hungary.
C3 University of Portsmouth; Tokyo Metropolitan University; Budapest
   University of Technology & Economics
RP Ju, ZJ (通讯作者)，Univ Portsmouth, Sch Comp, Portsmouth, Hants, England.
EM charles.phiri@cc-initiative.com; cristina.valle@cc-initiative.com;
   botzheim@mogi.bme.hu; zhaojie.ju@port.ac.uk; honghai.liu@port.ac.uk
RI ; Botzheim, Janos/B-2763-2014; Ju, Zhaojie/AAA-5872-2019
OI Liu, Honghai/0000-0002-2880-4698; 
FU European Regional Develop-ment Fund; National Natural Science Foundation
   of China [52075530]; Janos Bolyai Research Scholarship of the Hungarian
   Academy of Sciences, Hungary
FX The authors would like to acknowledge the support from the AiBle project
   co-financed by the European Regional Develop-ment Fund and National
   Natural Science Foundation of China (grant No. 52075530) . Janos
   Botzheim was supported by the Janos Bolyai Research Scholarship of the
   Hungarian Academy of Sciences, Hungary.
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NR 53
TC 4
Z9 5
U1 0
U2 9
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0019-0578
EI 1879-2022
J9 ISA T
JI ISA Trans.
PD NOV
PY 2021
VL 117
BP 16
EP 27
DI 10.1016/j.isatra.2021.01.046
EA SEP 2021
PG 12
WC Automation & Control Systems; Engineering, Multidisciplinary;
   Instruments & Instrumentation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Automation & Control Systems; Engineering; Instruments & Instrumentation
GA WH9WO
UT WOS:000708020200002
PM 33581890
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Jia, Z
   Yu, B
   Jiang, D
   Chang, ZQ
   Wan, SY
AF Jia, Zhen
   Yu, Bo
   Jiang, Di
   Chang, Zhengqi
   Wan, Shiyong
TI Case Report: A rare but critical complication in patients with lumbar
   infection combined with cauda equina syndrome-sacrococcygeal pressure
   sores
SO FRONTIERS IN MEDICINE
LA English
DT Article
DE cauda equina syndrome; complication prevention; lumbar spine infection;
   pressure injury; pressure sore; Vacuum Sealing Drainage
ID WOUND THERAPY; ABSCESS
AB This report presents a complex case of a 65-year-old male patient with a lumbar spine infection (T12-L1) caused by Staphylococcus aureus, leading to cauda equina syndrome, and subsequently developing a massive infectious pressure sore in the sacrococcygeal region. Back pain due to spinal infections, analgesic use, neurological deficits, and systemic infections masked the early signs of the pressure sore. Prolonged immobilization and neurogenic bladder and bowel incontinence led to a 5 cm & times; 5 cm deep pressure sore in the sacrococcygeal area. Involving a single-stage surgery for debriding the spinal lesion and performing internal fixation, along with debriding the sacrococcygeal ulcer using Vacuum Sealing Drainage (VSD) in both infected areas, this treatment not only aids in infection control but also reduces the overall treatment duration. Through multiple VSD changes, antimicrobial therapy, and nutritional support, the spinal infection was cured, and the pressure sore wound healed. This case underscores the importance of early prevention and identification of sacrococcygeal ulcers in patients with lumbar spine infections and neurological deficits to prevent the occurrence and progression of this severe complication.
C1 [Jia, Zhen; Yu, Bo; Jiang, Di; Wan, Shiyong] 961th Hosp PLA, Dept Orthoped, Qiqihar, Peoples R China.
   [Chang, Zhengqi] 960th Hosp PLA, Dept Orthoped, Jinan, Peoples R China.
RP Wan, SY (通讯作者)，961th Hosp PLA, Dept Orthoped, Qiqihar, Peoples R China.; Chang, ZQ (通讯作者)，960th Hosp PLA, Dept Orthoped, Jinan, Peoples R China.
EM 26766771@qq.com; wanshiyong961@163.com
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NR 18
TC 0
Z9 0
U1 0
U2 0
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
EI 2296-858X
J9 FRONT MED-LAUSANNE
JI Front. Med.
PD MAR 6
PY 2026
VL 13
AR 1776438
DI 10.3389/fmed.2026.1776438
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA FH5IQ
UT WOS:001718895300001
PM 41868212
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Wedemeyer, J
   Kubicka, S
   Lankisch, TO
   Wirth, T
   Patecki, M
   Hiss, M
   Manns, MP
   Schneider, AS
AF Wedemeyer, Jochen
   Kubicka, Stefan
   Lankisch, Tim O.
   Wirth, Thomas
   Patecki, Margret
   Hiss, Marcus
   Manns, Michael P.
   Schneider, Andrea S.
TI Transgastrically placed endoscopic vacuum-assisted closure system as an
   addition to transgastric necrosectomy in necrotizing pancreatitis
SO GASTROINTESTINAL ENDOSCOPY
LA English
DT Article
ID PRESSURE WOUND THERAPY; ESOPHAGEAL LEAKAGE
AB Background: Endoscopic transluminal debridement of infected pancreatic necrosis has been proved to be an important alternative to surgical debridement. Recently, endoscopic vacuum-assisted closure (EVAC) has been described as a new effective treatment option in upper intestinal anastomotic leaks.
   Objective: To test whether the EVAC can be applied to transgastrically accessible infected cavities.
   Design: Single-center case study.
   Setting: Academic medical center.
   Patients: Two patients with necrotizing pancreatitis.
   Main Outcome Measurement: Successful closure of leak.
   Results: We successfully applied EVAC to treat transgastrically accessible necrotic cavities.
   Limitations: Small case number.
   Conclusions: EVAC might be an important additional endoscopic treatment option for infected pancreatic necrosis, especially if established endoscopic treatment options fail.
C1 [Wedemeyer, Jochen; Kubicka, Stefan; Lankisch, Tim O.; Wirth, Thomas; Manns, Michael P.; Schneider, Andrea S.] Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, D-3000 Hannover, Germany.
   [Patecki, Margret; Hiss, Marcus] Hannover Med Sch, Dept Nephrol, D-3000 Hannover, Germany.
   [Wedemeyer, Jochen] Robert Koch Hosp Gehrden, Dept Med 1, Gehrden, Germany.
   [Kubicka, Stefan] Kreiskliniken Reutlingen, Dept Med 1, Reutlingen, Germany.
C3 Hannover Medical School; Hannover Medical School
RP Wedemeyer, J (通讯作者)，Klinikum Reg Hannover, Robert Koch Hosp, Dept Med 1, Von Reden Str 1, D-30989 Gehrden, Germany.
EM jochen.wedemeyer@krh.eu
RI Patecki, Margret/GLQ-8590-2022; Manns, Michael/AFG-3063-2022
CR Ahrens M, 2010, ENDOSCOPY, V42, P693, DOI 10.1055/s-0030-1255688
   Banks PA, 2006, AM J GASTROENTEROL, V101, P2379, DOI 10.1111/j.1572-0241.2006.00856.x
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   Holle G, 2007, UNFALLCHIRURG, V110, P490, DOI 10.1007/s00113-007-1267-x
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   Thompson JT, 2007, CLIN PLAST SURG, V34, P673, DOI 10.1016/j.cps.2007.07.005
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NR 12
TC 16
Z9 20
U1 0
U2 0
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0016-5107
J9 GASTROINTEST ENDOSC
JI Gastrointest. Endosc.
PD DEC
PY 2012
VL 76
IS 6
BP 1238
EP 1241
DI 10.1016/j.gie.2012.08.014
PG 4
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA 040TT
UT WOS:000311347800020
PM 23025973
DA 2026-07-24
ER

PT J
AU Carassou-Maillan, A
   Savary, D
   Jacquetin, B
AF Carassou-Maillan, A.
   Savary, D.
   Jacquetin, B.
TI Necrotizing fasciitis and double bowel perforation after retropubic
   sub-urethral sling
SO JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION
LA French
DT Article
DE Necrotizing fasciitis; Tension-free vaginal tape (TVT) procedure; Bowel
   perforation; Vacuum-assisted closure system; Retropubic sub-urethral
   sling
AB A 60-year-old woman without medical history developed after a Tension-free Vaginal Tape (TVT) procedure a necrotizing fasciitis and an abscess. After unadapted initial treatment, surgical procedure revealed 2 bowel perforations caused by the sling. Treatment was achieved by total mesh removal, bowel repair, necrosis excision and vacuum-assisted closure system. This is the first case report about the association of necrotizing fasciitis and double bowel perforations after TVT procedure. Any critical sepsis or with unsatisfactory evolution after retropubic sub-urethral sling has to make look for a digestive wound. (c) 2013 Elsevier Masson SAS. All rights reserved.
C1 [Carassou-Maillan, A.; Savary, D.; Jacquetin, B.] CHU Estaing, F-63003 Clermont Ferrand 1, France.
C3 Universite Clermont Auvergne (UCA); CHU Clermont Ferrand
RP Carassou-Maillan, A (通讯作者)，CHU Estaing, 1 Pl Lucie Aubrac, F-63003 Clermont Ferrand 1, France.
EM ananda_carassoumaillan@yahoo.fr
CR Bader G, 2009, J GYNECOL OBST BIO R, V38, pS201, DOI 10.1016/S0368-2315(09)73579-3
   Bafghi A, 2005, J Gynecol Obstet Biol Reprod (Paris), V34, P606
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   Gallup DG, 2002, AM J OBSTET GYNECOL, V187, P305, DOI 10.1067/mob.2002.126000
   Ghanimeh J, 2008, EUR J OBSTET GYN R B, V140, P286, DOI 10.1016/j.ejogrb.2008.01.005
   Johnson DW, 2003, INT UROGYNECOL J, V14, P291, DOI 10.1007/s00192-003-1064-1
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   ULMSTEN U, 1995, SCAND J UROL NEPHROL, V29, P75, DOI 10.3109/00365599509180543
NR 10
TC 2
Z9 2
U1 0
U2 0
PU ELSEVIER MASSON, CORP OFF
PI PARIS
PA 65 CAMILLE DESMOULINS CS50083 ISSY-LES-MOULINEAUX, 92442 PARIS, FRANCE
SN 0368-2315
EI 1773-0430
J9 J GYNECOL OBST BIO R
JI J. Gynecol. Obstet. Biol. Reprod.
PD OCT
PY 2014
VL 43
IS 8
BP 629
EP 632
DI 10.1016/j.jgyn.2013.08.011
PG 4
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA AR6IT
UT WOS:000343688100010
PM 24332737
DA 2026-07-24
ER

PT J
AU Qu, WQ
   Ni, SQ
   Wang, ZH
   Zhao, Y
   Zhang, SM
   Cheng, YH
   Liu, T
   Yu, M
   Wang, D
AF Qu, Wenqing
   Ni, Shuqin
   Wang, Zhenhai
   Zhao, Yong
   Zhang, Shimin
   Cheng, Yiheng
   Liu, Tong
   Yu, Min
   Wang, Dan
TI Severe open Lisfranc injuries: one-stage operation through internal
   fixation associated with vacuum sealing drainage
SO JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
LA English
DT Article
DE Lisfranc joints injury; Openness; k-wire internal fixation; VSD
ID OPEN REDUCTION; PRIMARY ARTHRODESIS
AB Background: This study aimed to investigate the clinical feasibility of treating severe open Lisfranc injuries by means of one-stage internal fixation with k-wires associated with vacuum sealing drainage (VSD).
   Methods: The clinical outcomes of 20 cases of severe open Lisfranc joint fracture-dislocation treated by using one-stage internal fixation with k-wires associated with VSD, after debridement and suturing during emergency treatment, were reviewed.
   Results: At 6 and 12 months after surgery, the American Orthopaedic Foot and Ankle Society midfoot scores were 69.2 and 78.2, the positive rates were 75 and 85 %, and the average visual analogue scale scores were 4.3 and 1.3, respectively. The average time of internal fixation surgery was 47 min (30-70 min). There were three cases of wound-edge necrosis; however, there were no cases of skin necrosis around the incision, or deep infection. The mean time of first hospital stay was 16.1 days (10-23 days).
   Conclusions: Treatment of severe open Lisfranc fracture and dislocation through one-stage internal fixation with k-wires in association with VSD led to fast anatomical reduction, stabilized bony structure, fast soft tissue recovery, and good short-term follow-up results.
C1 [Qu, Wenqing; Ni, Shuqin; Wang, Zhenhai; Zhao, Yong; Cheng, Yiheng; Liu, Tong; Yu, Min; Wang, Dan] Yantaishan Hosp, Dept Orthopaed & Trauma, Yantai 264008, Peoples R China.
   [Zhang, Shimin] Tongji Univ, Yangpu Hosp, Dept Orthopaed, Shanghai 200090, Peoples R China.
C3 Tongji University
RP Wang, D (通讯作者)，Yantaishan Hosp, Dept Orthopaed & Trauma, Yantai 264008, Peoples R China.
EM danwangdoc@126.com
RI ZHANG, Shimin/NUP-4492-2025
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   Tarkin IS, 2008, INJURY, V39, P142, DOI 10.1016/j.injury.2007.07.024
   Tarkin Ivan S, 2008, Foot Ankle Clin, V13, P705, DOI 10.1016/j.fcl.2008.08.002
   Thompson Michael C, 2003, J Am Acad Orthop Surg, V11, P260
   Welck MJ, 2015, INJURY, V46, P536, DOI 10.1016/j.injury.2014.11.026
   Younger AS, 2005, FOOT ANKLE INT, V26, P820, DOI 10.1177/107110070502601006
   Zonno AJ, 2011, FOOT ANKLE CLIN, V16, P35, DOI 10.1016/j.fcl.2010.12.004
NR 22
TC 11
Z9 17
U1 0
U2 5
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-799X
J9 J ORTHOP SURG RES
JI J. Orthop. Surg. Res.
PD NOV 4
PY 2016
VL 11
AR 134
DI 10.1186/s13018-016-0471-1
PG 7
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA EB1DU
UT WOS:000387088300001
PM 27814724
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kähler, G
AF Kaehler, Georg
TI Anastomotic Leakage after Upper Gastrointestinal Surgery: Endoscopic
   Treatment
SO VISCERAL MEDICINE
LA English
DT Review
DE Anastomotic leakage; Endoscopic management; EndoVAC therapy;
   Self-expanding metal stents; Clipping
ID VACUUM-ASSISTED CLOSURE; RESECTION; DEVICE
AB Anastomotic leakages substantially influence the outcome of patients after major surgery of the upper gastrointestinal tract. Endoscopy is important for making a diagnosis and for managing anastomotic leakages. By means of endoscopic inspection of the anastomotic site, not only the size and position of dehiscences but also the blood supply of the anastomotic region and an imminent leakage can be assessed. To close anastomotic leakages, several therapeutic methods are available, i.e. stenting, clipping, and the application of glue. In the majority of cases, the endoscopic application of a sponge for permanent suction (endoscopic vacuum-assisted closure therapy) is promising. (C) 2017 S. Karger GmbH, Freiburg
C1 [Kaehler, Georg] Heidelberg Univ, Med Ctr Mannheim, Cent Interdisciplinary Endoscopy, Mannheim, Germany.
C3 Ruprecht Karls University Heidelberg
RP Kähler, G (通讯作者)，Univ Med Mannheim, ZIE, Theodor Kutzer Ufer 1-3, D-68167 Mannheim, Germany.
EM georg.kaehler@umm.de
CR Feith M, 2011, CLIN GASTROENTEROL H, V9, P202, DOI 10.1016/j.cgh.2010.12.010
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   Groitl H, 1987, Surg Endosc, V1, P93, DOI 10.1007/BF00312692
   Haito-Chavez Y, 2014, GASTROINTEST ENDOSC, V80, P610, DOI 10.1016/j.gie.2014.03.049
   Kuehn F, 2017, SURG ENDOSC, V31, P3449, DOI 10.1007/s00464-016-5404-x
   Lippert E, 2011, INT J COLORECTAL DIS, V26, P303, DOI 10.1007/s00384-010-1104-5
   Loske G, 2016, ENDOSCOPY, V48, pE148, DOI 10.1055/s-0042-106576
   Loske G, 2009, GASTROINTEST ENDOSC, V69, P601, DOI 10.1016/j.gie.2008.06.058
   Manta R, 2016, UNITED EUR GASTROENT, V4, P770, DOI 10.1177/2050640615626051
   Rodella L, 1998, ENDOSCOPY, V30, P453, DOI 10.1055/s-2007-1001307
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   Schaible A, 2014, SURG ENDOSC, V28, P2078, DOI 10.1007/s00464-014-3435-8
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   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
NR 14
TC 22
Z9 27
U1 0
U2 5
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 2297-4725
EI 2297-475X
J9 VISC MED
JI Visc. Med.
PY 2017
VL 33
IS 3
BP 202
EP 206
DI 10.1159/000475783
PG 5
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA EZ5IE
UT WOS:000404746800005
PM 28785568
OA Bronze
DA 2026-07-24
ER

PT J
AU Hofmann, HS
   Neu, R
   Potzger, T
   Schemm, R
   Grosser, C
   Szöke, T
   Sziklavari, Z
AF Hofmann, Hans-Stefan
   Neu, Reiner
   Potzger, Tobias
   Schemm, Rudolf
   Grosser, Christian
   Szoeke, Tamas
   Sziklavari, Zsolt
TI Minimally Invasive Vacuum-Assisted Closure Therapy With Instillation
   (Mini-VAC-Instill) for Pleural Empyema
SO SURGICAL INNOVATION
LA English
DT Article
DE pleural empyema; VAC-instill; minimally invasive thoracic surgery
AB Enthusiasm for minimally invasive thoracic surgery is increasing. Thoracoscopy plays a significant therapeutic role in the fibrinopurulent stage (stage II) of empyema, in which loculated fluid cannot often be adequately drained by chest tube alone. For some debilitated and septic patients, further procedures such as open-window thoracostomy (OWT) with daily wound care or vacuum-assisted closure (VAC) therapy are necessary. In the present article, we propose a new option of minimally invasive VAC therapy including a topical solution of the empyema without open-window thoracostomy (Mini-VAC-instill). Three patients who underwent surgery using this technique are also presented. The discussion is focused on the advantages and disadvantages of the approach.
C1 [Hofmann, Hans-Stefan; Schemm, Rudolf; Grosser, Christian; Szoeke, Tamas; Sziklavari, Zsolt] Hosp Barmherzige Bruder Regensburg, D-93049 Regensburg, Germany.
   [Neu, Reiner; Potzger, Tobias] Univ Regensburg, D-93053 Regensburg, Germany.
C3 University of Regensburg
RP Hofmann, HS (通讯作者)，Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, Prufeningerstr 86, D-93049 Regensburg, Germany.
EM hans-stefan.hofmann@barmherzige-regensburg.de
RI Sziklavari, Zsolt/AGI-2440-2022
CR CLAGETT OT, 1963, J THORAC CARDIOV SUR, V45, P141, DOI 10.1016/S0022-5223(19)32877-6
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   Engelmann C, 1998, SEPTISCHE THORAXCHIR
   Gabriel A, 2009, INT WOUND J, V6, P1, DOI 10.1111/j.1742-481X.2009.00628.x
   Gabriel A, 2008, INT WOUND J, V5, P399, DOI 10.1111/j.1742-481X.2007.00423.x
   Hofmann HS, 2012, ANN THORAC SURG, V93, P1741, DOI 10.1016/j.athoracsur.2011.12.039
   Hughes C E, 1991, Semin Respir Infect, V6, P94
   Kho P, 2011, INTERACT CARDIOV TH, V12, P724, DOI 10.1510/icvts.2010.247619
   Kramer A, 2013, SEPTISCHE THORAXCHIR, P83
   ROSENFELDT FL, 1981, THORAX, V36, P272, DOI 10.1136/thx.36.4.272
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NR 13
TC 10
Z9 15
U1 0
U2 0
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1553-3506
EI 1553-3514
J9 SURG INNOV
JI Surg. Innov.
PD JUN
PY 2015
VL 22
IS 3
BP 235
EP 239
DI 10.1177/1553350614540811
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CI2IE
UT WOS:000354568900003
PM 25049317
DA 2026-07-24
ER

PT J
AU Ramnarine, IR
   McLean, A
   Pollock, JCS
AF Ramnarine, IR
   McLean, A
   Pollock, JCS
TI Vacuum-assisted closure in the paediatric patient with post-cardiotomy
   mediastinitis
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article
DE cardiac surgery; sternotomy infection; negative pressure therapy
AB Mediastinitis has a high mortality and is a major cause for concern in the neonatal cardiac surgical population. Vacuum-Assisted Closure (V.A.C.) is a newly established technique for expediting healing in the management of wounds resistant to established treatments; this includes the treatment of post-cardiotomy mediastinitis in the adult cardiac surgical patient. We describe the previously unreported use of the V.A.C. device for the successful treatment of post-cardiotomy mediastinitis in an infant. The device also improved the mechanics of respiration. We discuss potential risks and benefits of V.A.C. and suggest guidelines for its use. (C) 2002 Elsevier Science B.V. All rights reserved.
C1 Royal Hosp Sick Children, Glasgow G3 8SJ, Lanark, Scotland.
C3 University of Glasgow
RP Ramnarine, IR (通讯作者)，Royal Hosp Sick Children, Dalnair St, Glasgow G3 8SJ, Lanark, Scotland.
EM ianrramnarine@hotmail.com
OI Ramnarine, Ian/0000-0003-0161-3098
CR Berg HF, 2000, ANN THORAC SURG, V70, P924, DOI 10.1016/S0003-4975(00)01524-1
   Bucalo Brian, 1993, Wound Repair and Regeneration, V1, P181, DOI 10.1046/j.1524-475X.1993.10308.x
   Davydov Iu A, 1992, Khirurgiia (Mosk), P21
   Mooney JF, 2000, CLIN ORTHOP RELAT R, P26
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
NR 7
TC 29
Z9 39
U1 0
U2 3
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
EI 1873-734X
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD DEC
PY 2002
VL 22
IS 6
BP 1029
EP 1031
AR PII S1010-7940(02)00562-6
DI 10.1016/S1010-7940(02)00562-6
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 627LF
UT WOS:000179934100031
PM 12467837
OA Bronze
DA 2026-07-24
ER

PT J
AU Greer, SE
   Adelman, M
   Kasabian, A
   Galiano, RD
   Scott, R
   Longaker, MT
AF Greer, SE
   Adelman, M
   Kasabian, A
   Galiano, RD
   Scott, R
   Longaker, MT
TI The use of subatmospheric pressure dressing therapy to close
   lymphocutaneous fistulas of the groin
SO BRITISH JOURNAL OF PLASTIC SURGERY
LA English
DT Article
DE lymphorrhea; subatmospheric pressure dressing therapy; lymphocutaneous
   fistulas; vacuum assisted closure
ID VACUUM-ASSISTED CLOSURE; ARTERIAL RECONSTRUCTION; WOUND CONTROL;
   FREE-FLAP; COMPLICATIONS; LYMPHORRHEA
AB Groin lymphorrhea is an uncommon but serious complication of vascular and cardiac surgery as well as interventional procedures that cannulate the femoral vessels. Treatment options are somewhat controversial. For lymphocutaneous fistulas, a commonly used current modality is early surgical ligation with the assistance of blue-dye staining of the lymphatic anatomy. The purpose of this case series is to give the first description of a new, less invasive, approach using subatmospheric pressure dressing therapy for the treatment of the challenging problem of lymphocutaneous fistulas of the groin. (C) 2000 The British Association of Plastic Surgeons.
C1 NYU Med Ctr, Inst Reconstruct Plast Surg, New York, NY 10016 USA.
   NYU Med Ctr, Div Vasc Surg, New York, NY 10016 USA.
   Presbyterian Med Ctr, Wound Care Clin N Texas, Dallas, TX USA.
C3 New York University; New York University
RP Greer, SE (通讯作者)，300 E 34th St,9th Floor, New York, NY 10016 USA.
OI Longaker, Michael/0000-0003-1430-8914; Adelman, Mark/0000-0001-9276-6131
CR AlSalman MMS, 1997, INT SURG, V82, P60
   [Anonymous], WOUND REPAIR REGENER
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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   Greer S, 1998, ANN PLAS SURG, V41, P687, DOI 10.1097/00000637-199812000-00022
   Greer S E, 1999, J Wound Ostomy Continence Nurs, V26, P250
   Greer SE, 1999, ANN PLAS SURG, V43, P551, DOI 10.1097/00000637-199911000-00016
   GREER SE, IN PRESS ANN THORACI
   Kent RC, 1996, SURGERY, V119, P378
   KHALIL IM, 1987, J VASC SURG, V6, P93, DOI 10.1067/mva.1987.avs0060093
   KWAAN JHM, 1979, ARCH SURG-CHICAGO, V114, P1416
   Mirazimov B M, 1966, Ortop Travmatol Protez, V27, P19
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
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NR 22
TC 32
Z9 668
U1 0
U2 0
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE,
   LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0007-1226
J9 BRIT J PLAST SURG
JI Br. J. Plast. Surg.
PD SEP
PY 2000
VL 53
IS 6
BP 484
EP 487
DI 10.1054/bjps.2000.3360
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 345WC
UT WOS:000088837300006
PM 10927677
OA Bronze
DA 2026-07-24
ER

PT J
AU Chiang, IH
   Chen, SG
   Wang, CH
AF Chiang, I-Han
   Chen, Shyi-Gen
   Wang, Chih-Hsin
TI Treatment of Sternal Wound Infection Using a Free Myocutaneous Flap
SO ANNALS OF THORACIC SURGERY
LA English
DT Editorial Material
ID VACUUM-ASSISTED CLOSURE; CARDIAC-SURGERY; HEART-SURGERY; RECONSTRUCTION;
   MEDIASTINITIS
AB Deep sternal wound infections are potentially life-threatening complications after cardiac operations because they can spread into the mediastinum and cause postoperative morbidity and mortality. We present a 65-year-old man with a history of coronary artery bypass grafting. A large sternal defect was left after debridement. After brief vacuum-assisted closure (VAC), a free myocutaneous flap of the anterolateral thigh (ALT) was used to fill the dead space. At the 9-month follow-up, the wound had healed completely without tissue loss or complications, and the patient returned to normal life. This was a successful treatment of a deep sternal wound with free flap coverage. (C) 2015 by The Society of Thoracic Surgeons
C1 [Chiang, I-Han; Chen, Shyi-Gen; Wang, Chih-Hsin] Triserv Gen Hosp, Dept Surg, Div Plast Surg, Natl Def Med Ctr, Taipei 114, Taiwan.
C3 National Defense Medical University; Tri-Service General Hospital
RP Wang, CH (通讯作者)，Triserv Gen Hosp, Dept Surg, Div Plast Surg, 325,Sec 2,Cheng Kung Rd, Taipei 114, Taiwan.
EM super-derrick@yahoo.com.tw
CR Antohi N, 2014, CHIRURGIA-BUCHAREST, V109, P670
   Bapat V, 2008, J CARDIAC SURG, V23, P227, DOI 10.1111/j.1540-8191.2008.00595.x
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   Chang EI, 2013, ANN PLAS SURG, V71, P84, DOI 10.1097/SAP.0b013e31824872d9
   De Feo M, 2011, TEX HEART I J, V38, P375
   Greig AVH, 2007, J PLAST RECONSTR AES, V60, P372, DOI 10.1016/j.bjps.2006.10.005
   Gummert JF, 2002, THORAC CARDIOV SURG, V50, P87, DOI 10.1055/s-2002-26691
   JULIAN OC, 1957, SURGERY, V42, P753
   Lo S, 2014, ANN PLAS SURG, V73, P588, DOI 10.1097/SAP.0b013e318284084b
   Scholl L, 2004, J CARDIAC SURG, V19, P453, DOI 10.1111/j.0886-0440.2004.05002.x
NR 10
TC 7
Z9 8
U1 0
U2 6
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD NOV
PY 2015
VL 100
IS 5
BP 1907
EP 1910
DI 10.1016/j.athoracsur.2015.01.078
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA CX6OM
UT WOS:000365820400077
PM 26522542
OA Bronze
DA 2026-07-24
ER

PT J
AU Hofmann, HS
   Schemm, R
   Grosser, C
   Szöke, T
   Sziklavari, Z
AF Hofmann, Hans-Stefan
   Schemm, Rudolf
   Grosser, Christian
   Szoeke, Tamas
   Sziklavari, Zsolt
TI Vacuum-Assisted Closure of Pleural Empyema Without Classic Open-Window
   Thoracostomy
SO ANNALS OF THORACIC SURGERY
LA English
DT Editorial Material
AB A 64-year-old man was diagnosed with complex empyema after a second course of palliative chemotherapy for metastatic lung cancer. Because of the poor general condition of the patient, the decision was made to proceed with vacuum-assisted closure (VAC) therapy of the empyema without Eloesser or Clagett open-window thoracostomy (OWT). Installation and changing of the VAC sponge were performed using the ALEXIS Wound Protector/Retractor (Applied Medical, Rancho Santa Margarita, CA), a flexible polymer membrane tube. After 10 days of VAC treatment, the pleural cavity was sterile and was closed with single stitches. Chemotherapy was resumed 1 week later. (Ann Thorac Surg 2012;93:1741-2) (c) 2012 by The Society of Thoracic Surgeons
C1 [Hofmann, Hans-Stefan] Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, D-93049 Regensburg, Germany.
   Univ Regensburg, Dept Thorac Surg, Regensburg, Germany.
C3 University of Regensburg
RP Hofmann, HS (通讯作者)，Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, Prufeningerstr 86, D-93049 Regensburg, Germany.
EM hans-stefan.hofmann@barmherzige-regensburg.de
RI Sziklavari, Zsolt/AGI-2440-2022
CR Clagett O, 1963, J THORAC CARDIOVASC, V44, P141
   Eloesser L, 1935, SURG GYNECOL OBSTET, V60, P1096
   Kho P, 2011, INTERACT CARDIOV TH, V12, P724, DOI 10.1510/icvts.2010.247619
   SHAPIRO MP, 1988, AM J ROENTGENOL, V150, P549, DOI 10.2214/ajr.150.3.549
   Sziklavari Z, 2011, THORAC CARDIOV SURG, V6, P130
   Varker KA, 2006, ANN THORAC SURG, V81, P723, DOI 10.1016/j.athoracsur.2004.10.040
   WEISSBERG D, 1982, CHEST, V82, P447, DOI 10.1378/chest.82.4.447
NR 7
TC 19
Z9 24
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD MAY
PY 2012
VL 93
IS 5
BP 1741
EP 1742
DI 10.1016/j.athoracsur.2011.12.039
PG 2
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 935RZ
UT WOS:000303539200070
PM 22541219
OA Bronze
DA 2026-07-24
ER

PT J
AU Ni, JQ
   Liu, HZ
   Liu, XY
   Zhou, LG
   Sun, YJ
   Shi, P
   Hao, W
   Su, H
   Wang, X
AF Ni, Jianqiang
   Liu, Hongzhi
   Liu, Xiaoyang
   Zhou, Lugang
   Sun, Yujie
   Shi, Peng
   Hao, Wei
   Su, Hao
   Wang, Xin
TI Vacuum Sealing Drainage as Treatment of Severe Buttocks and Perianal
   Infection A Case Report and Review of the Literature
   (Care-Compliant)
SO MEDICINE
LA English
DT Article
ID ASSISTED CLOSURE; WOUNDS
AB Vacuum sealing is a therapeutic concept to achieve secure and rapid wound healing in traumatic soft tissue damage. Its application and effect in the treatment of severe buttocks and perianal infection are unclear.We describe a case of buttocks and perianal infection using the vacuum sealing drainage (VSD) technique. A 58-year-old man was admitted with buttocks and perianal severe infection, which was caused by injection. The size of the wounds was 40x30cm. Colostomy was applied prior to the prompt surgical debridement to prevent defecation and keep the perianal region clean. Emergency debridement was then conducted. After the wounds were thoroughly washed with conventional disinfection solution, they were then covered by VSD system.The infection was controlled 9 days after the first surgery by prompt surgical debridement, the application of VSD treatment, and the use of narrow-spectrum antibiotics based on susceptibility result. After 3 applications of VSD treatment, skin grafting harvested from the left leg was conducted. All free skin grafts survived at 8 weeks. Colon was placed back into the abdominal cavity finally.Initial colostomy and debridement, the temporary VSD cover followed after several days by skin grafting is a reliable treatment regimen for severe buttocks and perianal infection.
C1 [Ni, Jianqiang; Liu, Hongzhi; Liu, Xiaoyang; Zhou, Lugang; Sun, Yujie; Shi, Peng; Hao, Wei; Su, Hao; Wang, Xin] Qingdao Univ, Yuhuangding Hosp, Yantai, Shandong, Peoples R China.
C3 Qingdao University
RP Wang, X (通讯作者)，Qingdao Univ, Yuhuangding Hosp, Yantai, Shandong, Peoples R China.
EM jone-20002@163.com
RI Liu, Hongzhi/LKL-8900-2024
CR A Novak, 2014, Open Orthop J, V8, P168, DOI 10.2174/1874325001408010168
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Etoz A, 2004, TURK PLAST REKONSTR, V12, P102
   Li RG, 2013, MED SCI MONITOR, V19, P510, DOI 10.12659/MSM.883963
   Liu L, 2012, INT ORTHOP, V36, P1441, DOI 10.1007/s00264-011-1404-6
   Tang J, 2010, CHIN J TRAUMATOL, V13, P289, DOI 10.3760/cma.j.issn.1008-1275.2010.05.007
   Wu JF, 2014, BREAST CARE, V9, P273, DOI 10.1159/000365954
   Yang YH, 2013, J PLAST RECONSTR AES, V66, pE209, DOI 10.1016/j.bjps.2013.03.006
   Ye JN, 2015, MEDICINE, V94, DOI 10.1097/MD.0000000000000426
NR 9
TC 8
Z9 12
U1 1
U2 12
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD OCT
PY 2015
VL 94
IS 43
AR e1766
DI 10.1097/MD.0000000000001766
PG 3
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA DC9IS
UT WOS:000369535500021
PM 26512571
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Batra, RK
   Aseeja, V
AF Batra, R. K.
   Aseeja, Veena
TI VAC Therapy in Large Infected Sacral Pressure Ulcer Grade IV-Can Be an
   Alternative to Flap Reconstruction?
SO INDIAN JOURNAL OF SURGERY
LA English
DT Article
DE Vacuum-assisted closure (VAC) therapy; Flap surgery
AB Vacuum-assisted closure (VAC) therapy is a new entrant in wound care after growth factors and alginate or hydrocolloid dressing, in the treatment of pressure ulcers. We have been using this technique for diabetic foot ulcers. A young nondiabetic man presented with a large sacral bed sore after high doses of ionotropes in an intensive care unit for treating severe hypotension. His wound was debrided, and instead of flap surgery in such infected wound, he was treated with VAC therapy. The complete wound healing was achieved in 6 weeks and at half the cost of flap surgery. Moreover, the chances of flap failure and its related complications were eliminated.
C1 [Batra, R. K.] Alchemist Hosp, Sect 21, Panchkula, Haryana, India.
   [Aseeja, Veena] MMIMSR, Mullana, Haryana, India.
C3 Maharishi Markandeshwar University
RP Batra, RK (通讯作者)，Alchemist Hosp, Sect 21, Panchkula, Haryana, India.
EM rkbatra70@rediffmail.com
CR Bassetto F, 2012, J PLAST RECONSTR AES, V65, P91, DOI 10.1016/j.bjps.2011.08.016
   Baynham S., 1999, OSTOMY WOUND MANAGE, V45, P34
   Gupta Subhas, 2004, Adv Skin Wound Care, V17 Suppl 2, P1, DOI 10.1097/00129334-200411002-00001
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NR 7
TC 7
Z9 10
U1 0
U2 11
PU SPRINGER INDIA
PI NEW DELHI
PA 7TH FLOOR, VIJAYA BUILDING, 17, BARAKHAMBA ROAD, NEW DELHI, 110 001,
   INDIA
SN 0972-2068
EI 0973-9793
J9 INDIAN J SURG
JI Indian J. Surg
PD APR
PY 2014
VL 76
IS 2
BP 162
EP 164
DI 10.1007/s12262-012-0770-7
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AI6KD
UT WOS:000336981800019
PM 24891788
OA Bronze
DA 2026-07-24
ER

PT J
AU Xu, LQ
   Zhao, XX
   Wang, PX
   Yang, J
   Yang, YM
AF Xu, Li-Qian
   Zhao, Xin-Xiu
   Wang, Pei-Xia
   Yang, Ji
   Yang, Yun-Mei
TI Multidisciplinary treatment of a patient with necrotizing fasciitis
   caused by Staphylococcus aureus: A case report
SO WORLD JOURNAL OF CLINICAL CASES
LA English
DT Article
DE Necrotizing fasciitis; Surgical debridement; Vacuum sealing drainage;
   Multidisciplinary treatment; Case report
ID DIAGNOSIS; THERAPY
AB BACKGROUND
   Necrotizing fasciitis is a severe bacterial skin infection that spreads quickly and is characterized by extensive necrosis of the deep and superficial fascia resulting in the devascularization and necrosis of associated tissues. Because of high morbidity and mortality, accurate diagnosis and early treatment with adequate antibiotics and surgical intervention are vital. And timely identification and treatment of complications are necessary to improve survival of patient.
   CASE SUMMARY
   We report a case of necrotizing fasciitis caused by Staphylococcus aureus in a patient using high doses of glucocorticoid and suffering from secondary diabetes mellitus. He was admitted to our hospital due to redness and oedema of the lower limbs. After admission, necrotizing fasciitis caused by Staphylococcus aureus was considered, and he was discharged after B-ultrasound drainage and multiple surgical operations. In the process of treatment, multiple organ functions were damaged, but with the help of multi-disciplinary treatment, the patient got better finally.
   CONCLUSION
   The key to successful management of necrotizing fasciitis is an early and accurate diagnosis. The method of using vacuum sealing drainage in postoperative patients can keep the wound dry and clean, reduce infection rate, and promote wound healing. Interdisciplinary collaboration is a vital prerequisite for successful treatment.
C1 [Xu, Li-Qian; Zhao, Xin-Xiu; Wang, Pei-Xia; Yang, Ji; Yang, Yun-Mei] Zhejiang Univ, Affiliated Hosp 1, Coll Med, Dept Geriatr, 79 Qingchun Rd, Hangzhou 310003, Zhejiang, Peoples R China.
C3 Zhejiang University
RP Yang, YM (通讯作者)，Zhejiang Univ, Affiliated Hosp 1, Coll Med, Dept Geriatr, 79 Qingchun Rd, Hangzhou 310003, Zhejiang, Peoples R China.
EM 1194070@zju.edu.cn
FU National Key Clinical Specialities in the Twelfth Five-Year Plan
   (Geriatrics Department); China Health Promotion Foundation
FX Supported by National Key Clinical Specialities in the Twelfth Five-Year
   Plan (Geriatrics Department); "Demonstration Base of Clinical Nutrition
   for the Elderly" initiated and sponsored by the China Health Promotion
   Foundation.
CR [Anonymous], 2014, CURR PROB SURG, V51, P344, DOI 10.1067/j.cpsurg.2014.06.001
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NR 25
TC 4
Z9 4
U1 0
U2 11
PU BAISHIDENG PUBLISHING GROUP INC
PI PLEASANTON
PA 7041 Koll Center Parkway, Suite 160, PLEASANTON, CA, UNITED STATES
SN 2307-8960
J9 WORLD J CLIN CASES
JI World J. Clin. Cases
PD NOV 6
PY 2019
VL 7
IS 21
BP 3595
EP 3602
DI 10.12998/wjcc.v7.i21.3595
PG 8
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA JX1BK
UT WOS:000503477700021
PM 31750343
OA Green Accepted, gold
DA 2026-07-24
ER

PT J
AU Zhang, HY
   Li, QY
AF Zhang, Hengyan
   Li, Qiyi
TI Improved vacuum sealing drainage for treatment of surgical site
   infection following posterior spinal internal fixation A case report
SO MEDICINE
LA English
DT Article
DE posterior spine surgery; spinal internal fixation; surgical site
   infection; vacuum sealing drainage
ID EXPERIENCE; FUSION
AB Rationale: Surgical site infection (SSI) following spine surgeries involving internal fixation often require removing the instrument; however, this can cause spinal instability. Previous reports have demonstrated the usefulness of vacuum sealing drainage (VSD) therapy, but the cases require wound opening, aseptic condition to replace the VSD device, and a secondary operation to close the wound. Thus, to improve the VSD treatment and develop a maneuverable procedure, make sense in spine surgery.
   Patients concerns: A 59-year-old male patient with a T12 vertebral fracture was affected by SSIs after spinal osteotomy with internal fixation.
   Diagnoses: The patient complained of wound exudation and had a fever 3 weeks after posterior spinal surgery. Initial serum investigations showed elevated white blood cell count and bacterial cultures of wound exudate were positive for Enterococcus faecalis. Therefore, SSI is confirmed.
   Interventions: The infection was not controlled after 2 debridements, so the patient was treated with VSD treatment. The VSD foam dressings containing a drainage tube were placed into the wound from the exudation site of the wound until they contacted the internal fixation devices. After covering external fixation devices, continuous drainage was performed for 24h. The VSD device was replaced every 4 to 5 days until the wound effusion stopped. All of the operations were performed at the bedside without complex manipulation or secondary closure under harsh aseptic condition.
   Outcomes: Wound exudation decreased remarkably and the infection was controlled 2 weeks after the application of VSD treatment. After 5 weeks, inflammatory indicators all decreased to normal levels and the exudate of the wound had stopped. The VSD treatment was then terminated and the drainage site of the wound was sutured. After 7 weeks, complete wound healing was achieved and no infection recurred during the 6-month follow-up.
   Lessons: VSD could be a reliable treatment for SSIs that require preservation of internal fixation. Complete opening of the wound during the VSD treatment and secondary wound closure surgery were avoided.
C1 [Li, Qiyi] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Orthoped, 1 Shuaifuyuan, Beijing 100730, Peoples R China.
   [Li, Qiyi] Peking Union Med Coll, 1 Shuaifuyuan, Beijing 100730, Peoples R China.
C3 Chinese Academy of Medical Sciences - Peking Union Medical College;
   Peking Union Medical College Hospital; Chinese Academy of Medical
   Sciences - Peking Union Medical College; Peking Union Medical College
RP Li, QY (通讯作者)，Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Orthoped, 1 Shuaifuyuan, Beijing 100730, Peoples R China.; Li, QY (通讯作者)，Peking Union Med Coll, 1 Shuaifuyuan, Beijing 100730, Peoples R China.
EM liqiyipumch@sina.com
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NR 13
TC 4
Z9 6
U1 1
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD FEB
PY 2018
VL 97
IS 7
AR e9952
DI 10.1097/MD.0000000000009952
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GA1ZQ
UT WOS:000428116700060
PM 29443786
OA gold
DA 2026-07-24
ER

PT J
AU Baradarian, S
   Stahovich, M
   Krause, S
   Adamson, R
   Dembitsky, W
AF Baradarian, Sam
   Stahovich, Marcia
   Krause, Susan
   Adamson, Robert
   Dembitsky, Walter
TI Case series: Clinical management of persistent mechanical assist device
   driveline drainage using vacuum-assisted closure therapy
SO ASAIO JOURNAL
LA English
DT Article
ID INFECTION
AB Percutaneous driveline lead and pocket sites are potential sources of drainage that can lead to infection. Some patients experience a slower closure of tissue growth into the driveline. The management of chronically open and or draining driveline wounds is a challenge. The KCl vacuum-assisted closure (VAC) device is a noninvasive negative-pressure therapy that promotes the healing of wounds not responding to conventional treatment. Vacuum-assisted closure therapy has proven safe, effective, and cost efficient by decreasing the number of dressing changes and length of stay. The left ventricular assist device (LVAD) team initiated VAC therapy in 3 patients. The tunneling method allowed the wound to heal from the inside out. The dressing was changed every 3 days, and the size and depth of the wound was monitored. Patients may be sent home using a portable VAC device until wound closure is obtained, which decreases the hospital length of stay. Our experience with three patients suggests the VAC device can be used for draining and tunneling LVAD driveline-site wounds and may prevent fistula formation. It is especially useful for patients with ascites that may be draining along the driveline tract. The sites showed increased granulation, decreased drainage, and a reduced bacterial burden after having the device in place.
C1 Sharp Mem Hosp & Rehabil Ctr, Mech Assist Device Dept, San Diego, CA 92123 USA.
   Sharp Mem Hosp & Rehabil Ctr, Wound Healing Dept, San Diego, CA 92123 USA.
C3 Sharp Memorial Hospital Rehabilitation & Physical Therapy; Sharp
   Memorial Hospital Rehabilitation & Physical Therapy
RP Stahovich, M (通讯作者)，Sharp Mem Hosp & Rehabil Ctr, Mech Assist Device Dept, 7901 Frost St, San Diego, CA 92123 USA.
CR Bentz Barbara, 2004, J Cardiovasc Manag, V15, P9
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NR 7
TC 32
Z9 33
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1058-2916
EI 1538-943X
J9 ASAIO J
JI Asaio J.
PD MAY-JUN
PY 2006
VL 52
IS 3
BP 354
EP 356
DI 10.1097/01.mat.0000204760.48157.cc
PG 3
WC Engineering, Biomedical; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Transplantation
GA 046UE
UT WOS:000237835800022
PM 16760728
DA 2026-07-24
ER

PT J
AU Egin, S
   Gökcek, B
   Yesiltas, M
   Hot, S
   Karakas, DÖ
AF Egin, Seracettin
   Gokcek, Berk
   Yesiltas, Metin
   Hot, Semih
   Karakas, Dursun Ozgur
TI Improvement of a duodenal leak: Two-way vacuum-assisted closure
SO ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA &
   EMERGENCY SURGERY
LA English
DT Article
DE Duodenal leak following omentoplasty; duodenal ulcer perforation;
   vacuum-assisted closure
AB A 55-year-old male patient developed a duodenal re-leak, which caused severe peritonitis, on the second postoperative day after surgery to treat an acutely perforated duodenal ulcer. Relaparotomy was performed 2 days after surgery for the re-leak after omentoplasty. The necrotic omentum was dissociated from the bulbus duodeni. Viable omentum for reinsertion of the omental patch was not found. The turned-outward duodenal mucosa was excised and the duodenal perforation was sutured. Two-way vacuum-assisted closure (VAC) was carried out by taking a liquid culture of the abdomen and washing the abdomen. The two-way VAC exchange procedures were continued every 3 days until the re-leak was terminated. The whole treatment process occurred in the intensive care unit. The duodenal leak was completely stopped by 41 days after surgery. The subcutaneous layer was dissected from the fascial layer of the anterior wall of the abdomen; thus, the abdominal skin was closed without tension and the patient was subsequently discharged. In conclusion, since primary source control is often difficult when treating duodenal leaks, the two-way VAC system is a convenient solution for localizing the source of the peritonitis and removing toxic peritoneal material.
C1 [Egin, Seracettin; Gokcek, Berk; Yesiltas, Metin; Hot, Semih; Karakas, Dursun Ozgur] Hlth Sci Univ, Okmeydani Training & Res Hosp, Dept Gen Surg, Istanbul, Turkey.
C3 University of Health Sciences Turkey; Istanbul Okmeydani Training &
   Research Hospital
RP Egin, S (通讯作者)，SBU, Okmeydani Egitim & Arastirma Hastanesi, Gen Cerrahi Klin, Istanbul, Turkey.
EM seracettin_egin@hotmail.com
RI Eğin, Seracettin/GQZ-0908-2022; /ADG-3811-2022; Karakas,
   Dursun/C-4089-2015; Yeşiltaş, Metin/R-3639-2018; Gökçek,
   Berk/X-9343-2018
OI Yeşiltaş, Metin/0000-0002-2080-1572; Gökçek, Berk/0000-0001-9989-4152
CR Chalya PL, 2011, WORLD J EMERG SURG, V6, DOI 10.1186/1749-7922-6-31
   Coccolini F, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0167-4
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NR 8
TC 2
Z9 4
U1 0
U2 3
PU TURKISH ASSOC TRAUMA EMERGENCY SURGERY
PI ISTANBUL
PA KOPRULU MEHMET PASA SOC, DENIZ ABDAL MAH, DADASOGLU AP, 25-1 SEHREMINI,
   ISTANBUL, 00000, TURKEY
SN 1306-696X
J9 ULUS TRAVMA ACIL CER
JI Ulus. Travma Acil Cerrahi Derg.
PD JAN
PY 2019
VL 25
IS 1
BP 89
EP 92
DI 10.5505/tjtes.2018.22934
PG 4
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA HP2DI
UT WOS:000461477900018
PM 30742295
OA Bronze
DA 2026-07-24
ER

PT J
AU Geerdes-Fenge, H
   Pongratz, P
   Liese, J
   Reisinger, E
AF Geerdes-Fenge, H. F.
   Pongratz, P.
   Liese, J.
   Reisinger, E. C.
TI Vacuum-assisted closure therapy of paradoxical reaction in tuberculous
   lymphadenopathy caused by Mycobacterium africanum
SO INFECTION
LA English
DT Article
DE Tuberculosis; Cervical lymph node; Paradoxical reaction; Fistula;
   Vacuum-assisted closure; VAC; Mycobacterium africanum
ID HIV; MANAGEMENT
AB A 26-year-old HIV-negative male from Ghana was treated for cervical, intrathoracic and abdominal lymph node tuberculosis (TB) and tuberculous hepatitis. Penetration of the thoracic trachea by a mediastinal lymph node had caused bronchomucosal TB. Sputum culture grew M. africanum, sensitive to all first-line antituberculous drugs. Four weeks after the beginning of directly observed treatment with isoniazid, rifampin, pyrazinamide and ethambutol, the right cervical lymph node increased in size, liquefied and caused a spontaneous fistula. A biopsy of the necrotized lymph node revealed rare acid-fast bacilli with a positive PCR for Mycobacterium tuberculosis complex. After debridement, vacuum-assisted closure therapy was performed for 6 weeks. Five months after the beginning of antituberculous therapy, a second paradoxical reaction occurred, with painful swelling of two contralateral supraclavicular lymph nodes. Extirpation of one node yielded a positive PCR for M. tuberculosis complex; the culture was negative. Antituberculous treatment was continued, and additional treatment with oral prednisolone 20 mg daily for 1 month tapering over 10 weeks was introduced, resulting in a decrease in lymphadenopathy. Antituberculous treatment was continued for a total of 9 months. The outcome was favorable, no further lymphadenopathy occurred over the following 6 months.
C1 [Geerdes-Fenge, H. F.; Pongratz, P.; Reisinger, E. C.] Dept Trop Med & Infect Dis, Rostock, Germany.
   [Liese, J.] Rostock Univ, Med Ctr, Dept Oral & Maxillofacial Facial Plast Surg, Ernst Heydemann Str 6, D-18057 Rostock, Germany.
C3 University of Rostock
RP Geerdes-Fenge, H (通讯作者)，Dept Trop Med & Infect Dis, Rostock, Germany.
EM hilte.geerdes-fenge@med.uni-rostock.de
OI Geerdes-Fenge, Hilte/0000-0003-2839-0015
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NR 20
TC 6
Z9 7
U1 0
U2 1
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0300-8126
EI 1439-0973
J9 INFECTION
JI Infection
PD JUN
PY 2018
VL 46
IS 3
BP 427
EP 430
DI 10.1007/s15010-017-1112-2
PG 4
WC Infectious Diseases
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases
GA GH8NC
UT WOS:000433924200018
PM 29330673
DA 2026-07-24
ER

PT J
AU Zhong, WD
   Hu, G
   Feng, ZH
   Shen, WD
   Shao, GY
AF Zhong, Wei-dong
   Hu, Gen
   Feng, Zhi-hua
   Shen, Wei-dong
   Shao, Guo-yi
TI Endoluminal Vacuum-Assisted Closure Therapy for Upper Gastrointestinal
   Leak, Perforation, and Fistula: A Case Series and Literature Review
SO DIGESTIVE DISEASES
LA English
DT Review
DE Endoluminal vacuum-assisted closure; Gastrointestinal fistula;
   Esophageal ruptures
ID MANAGEMENT; STENT
AB Background: With the increasing incidence of upper digestive tract tumors, more upper digestive tract surgeries are performed each year, and surgeons have difficulty in the postoperative management of gastrointestinal anastomotic fistula. The use of a new minimally invasive technique, endoluminal vacuum-assisted closure (E-VAC), has increased the success rate of the treatment of gastrointestinal fistula. Methods: We present 6 cases of gastrointestinal fistula treated in our hospital in 2021: 3 cases of anastomotic fistula after esophageal cancer surgery, 2 cases of anastomotic fistula after gastric cancer surgery, and one case of esophageal rupture after trauma. With E-VAC and other adjuvant treatment measures, the gastrointestinal fistulas were eventually closed or significantly reduced. Results: Both local and systemic infections in all 6 patients were controlled with the use of E-VAC device, resulting in significant reduction or closure of fistulas. Conclusion: E-VAC devices can effectively help in the removal of the exudate and necrotic tissue around the fistula, promote the proliferation of granulation tissue, and support closure of the fistula. However, further improvements to the device are needed to improve patient comfort and operational safety. (c) 2022 S. Karger AG, Basel
C1 [Zhong, Wei-dong; Hu, Gen; Feng, Zhi-hua; Shao, Guo-yi] Nantong Univ, Dept Gastrointestinal Surg, Jiangyin Peoples Hosp, Jiangyin, Peoples R China.
   [Zhong, Wei-dong] Soochow Univ, Dept Gastroenterol, Affiliated Hosp 1, Suzhou, Peoples R China.
   [Shen, Wei-dong] Nantong Univ, Dept Gastroenterol, Jiangyin Peoples Hosp, Jiangyin, Peoples R China.
C3 Nantong University; Soochow University - China; Nantong University
RP Shao, GY (通讯作者)，Nantong Univ, Dept Gastrointestinal Surg, Jiangyin Peoples Hosp, Jiangyin, Peoples R China.; Shen, WD (通讯作者)，Nantong Univ, Dept Gastroenterol, Jiangyin Peoples Hosp, Jiangyin, Peoples R China.
EM shenwd1976@126.com; doctorash@vip.sina.com
RI Feng, Zhihua/AAW-4313-2021
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NR 20
TC 3
Z9 3
U1 0
U2 4
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 0257-2753
EI 1421-9875
J9 DIGEST DIS
JI Dig. Dis.
PD MAY
PY 2023
VL 41
IS 3
BP 506
EP 512
DI 10.1159/000526713
EA OCT 2022
PG 7
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA R0IR2
UT WOS:000877149800001
PM 36288720
DA 2026-07-24
ER

PT J
AU Rubicondo, C
   Lovece, A
   Pinelli, D
   Indriolo, A
   Lucianetti, A
   Colledan, M
AF Rubicondo, Carolina
   Lovece, Andrea
   Pinelli, Domenico
   Indriolo, Amedeo
   Lucianetti, Alessandro
   Colledan, Michele
TI Endoluminal vacuum-assisted closure (E-Vac) therapy for postoperative
   esophageal fistula: successful case series and literature review
SO WORLD JOURNAL OF SURGICAL ONCOLOGY
LA English
DT Review
DE E-Vac therapy; Oesophageal fistula; Oesophageal leaks; Anastomotic
   leaks; Bronchogenic cyst
ID ANASTOMOTIC LEAKAGE; MANAGEMENT; PERFORATIONS
AB Background Treatment of esophageal perforations and postoperative anastomotic leaks of the upper gastrointestinal tract remains a challenge. Endoluminal vacuum-assisted closure (E-Vac) therapy has positively contributed, in recent years, to the management of upper gastrointestinal tract perforations by using the same principle of vacuum-assisted closure therapy of external wounds. The aim is to provide continuous wound drainage and to promote tissue granulation, decreasing the needed time to heal with a high rate of leakage closure. Cases presentation A series of two different cases with clinical and radiological diagnosis of esophageal fistulas, recorded from 2018 to 2019 period at our institution, is presented. The first one is a case of anastomotic leak after esophagectomy for cancer complicated by pleuro-mediastinal abscess, while the second one is a leak of an esophageal suture, few days after resection of a bronchogenic cyst perforated into the esophageal lumen. Both cases were successfully treated with E-Vac therapy. Conclusion Our experience shows the usefulness of E-Vac therapy in the management of anastomotic and non-anastomotic esophageal fistulas. Further research is needed to better define its indications, to compare it to traditional treatments and to evaluate its long-term efficacy.
C1 [Rubicondo, Carolina; Pinelli, Domenico; Colledan, Michele] ASST Papa Giovanni XXIII, Gen Surg 3, Bergamo, Italy.
   [Lovece, Andrea; Lucianetti, Alessandro] ASST Papa Giovanni XXIII, Gen Surg 1, Piazza OMS 1, I-24127 Bergamo, Italy.
   [Indriolo, Amedeo] ASST Papa Giovanni XXIII, Dept Gastroenterol & Endoscopy, Bergamo, Italy.
C3 ASST Papa Giovanni XXIII; ASST Papa Giovanni XXIII; ASST Papa Giovanni
   XXIII
RP Rubicondo, C (通讯作者)，ASST Papa Giovanni XXIII, Gen Surg 3, Bergamo, Italy.
EM carolinarubicondo1988@gmail.com
RI ; Colledan, Michele/JGM-6908-2023; Pinelli, Domenico/IAS-0685-2023
OI Lovece, Anea/0000-0002-5176-7303; Lucianetti,
   Alessandro/0000-0002-9035-697X
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NR 21
TC 17
Z9 23
U1 0
U2 11
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1477-7819
J9 WORLD J SURG ONCOL
JI World J. Surg. Oncol.
PD NOV 14
PY 2020
VL 18
IS 1
AR 301
DI 10.1186/s12957-020-02073-6
PG 7
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA OR0SR
UT WOS:000589188500001
PM 33189152
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Labler, L
   Keel, M
   Trentz, O
   Heinzelmann, M
AF Labler, Ludwig
   Keel, Marius
   Trentz, Otmar
   Heinzelmann, Michael
TI Wound conditioning by vacuum assisted closure (VAC) in postoperative
   infections after dorsal spine surgery
SO EUROPEAN SPINE JOURNAL
LA English
DT Article
DE spine; instrumentation; infection; vacuum assisted closure; topic
   negative pressure
ID PARASPINOUS MUSCLE FLAPS; SOFT-TISSUE DEFECTS; COMPLEX BACK WOUNDS;
   SUBATMOSPHERIC PRESSURE; RETROSPECTIVE ANALYSIS; IDIOPATHIC SCOLIOSIS;
   DELAYED INFECTIONS; RISK-FACTORS; CORD-INJURY; INSTRUMENTATION
AB The use of vacuum assisted closure (V.A.C.) therapy in postoperative infections after dorsal spinal surgery was studied retrospectively. Successful treatment was defined as a stable healed wound that showed no signs of acute or chronic infection. The treatment of the infected back wounds consisted of repeated debridement, irrigation and open wound treatment with temporary closure by V.A.C. The instrumentation was exchanged or removed if necessary. Fifteen patients with deep subfascial infections after posterior spinal surgery were treated. The implants were exchanged in seven cases, removed completely in five cases and left without changing in one case. In two cases spinal surgery consisted of laminectomy without instrumentation. In two cases only the wound defects were closed by muscle flap, the remaining ones were closed by delayed suturing. Antibiotic treatment was necessary in all cases. Follow up was possible in 14 patients. One patient showed a new infection after treatment. The study illustrates the usefulness of V.A.C. therapy as a new alternative management for wound conditioning of complex back wounds after deep subfascial infection.
C1 Univ Spital Zurich, Unfallchirurg Klin, Zurich, Switzerland.
C3 University of Zurich; University Zurich Hospital
RP Labler, L (通讯作者)，Univ Spital Zurich, Unfallchirurg Klin, Zurich, Switzerland.
EM ludwig.labler@usz.ch
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NR 70
TC 57
Z9 75
U1 0
U2 5
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013 USA
SN 0940-6719
J9 EUR SPINE J
JI Eur. Spine J.
PD SEP
PY 2006
VL 15
IS 9
BP 1388
EP 1396
DI 10.1007/s00586-006-0164-2
PG 9
WC Clinical Neurology; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Orthopedics
GA 082BW
UT WOS:000240362500013
PM 16835734
OA Green Submitted, Green Accepted
DA 2026-07-24
ER

PT J
AU Schimmer, C
   Sommer, SP
   Bensch, M
   Elert, O
   Leyh, R
AF Schimmer, C.
   Sommer, S. P.
   Bensch, M.
   Elert, O.
   Leyh, R.
TI Management of poststernotomy mediastinitis: Experience and results of
   different therapy modalities
SO THORACIC AND CARDIOVASCULAR SURGEON
LA English
DT Article
DE poststernotomy mediastinitis; vacuum assisted closure; primary reclosure
   with suction/irrigation system
ID VACUUM-ASSISTED CLOSURE; STERNAL WOUND-INFECTION; PERISTERNAL THORACIC
   WALL; CARDIAC-SURGERY; BLOOD-FLOW; DRAINAGE
AB Background: Different primary treatment modalities have been utilized to treat poststernotomy mediastinitis (PM) following cardiac surgery.
   Methods: A literature survey using the key phrases "treatment of deep sternal wound infection" and "poststernotomy-mediastinitis" was performed. Furthermore, a questionnaire regarding the primary treatment of PM was distributed to all 79 German heart surgery centers.
   Results: The review of the literature shows that the current understanding is based purely on retrospective studies, not on evidence-based medicine. All 79 German heart centers replied to the questionnaire. Vacuum-assisted closure therapy (V.A.C.(R)) is used in 28/79 (35%) heart centers as the "first-line" treatment, 22/79 (28%) perform primary reclosure in conjunction with a double-tube irrigation/suction system, and in 29/79 (37%) German heart centers both treatment options were used according to the intraoperative conditions.
   Conclusions: As a primary treatment for PM two treatment modalities are currently in use: primary reclosure coupled with a double-tube suction/irrigation system versus V.A.C.(R) therapy. Since prospective randomized studies have not yet been performed, controlled clinical trials comparing both treatment modalities are pivotal to define the evidence for patients presenting with PM.
C1 [Schimmer, C.; Sommer, S. P.; Bensch, M.; Elert, O.; Leyh, R.] Univ Hosp, Dept Heart Surg, D-97080 Wurzburg, Germany.
C3 University of Wurzburg
RP Schimmer, C (通讯作者)，Univ Hosp, Dept Heart Surg, Oberdurrbacherstr 6, D-97080 Wurzburg, Germany.
EM Schimmer_c@klinik.uni-wuerzburg.de
OI Sommer, Sebastian-Patrick/0000-0002-9990-5330
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NR 20
TC 31
Z9 34
U1 0
U2 1
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0171-6425
J9 THORAC CARDIOV SURG
JI Thorac. Cardiovasc. Surg.
PD JUN
PY 2008
VL 56
IS 4
BP 200
EP 204
DI 10.1055/s-2008-1038386
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 314WD
UT WOS:000256839000004
PM 18481237
DA 2026-07-24
ER

PT J
AU Chen, PM
   Vilorio, NC
   Dhatariya, K
   Jeffcoate, W
   Lobmann, R
   Mcintosh, C
   Piaggesi, A
   Steinberg, J
   Vas, P
   Viswanathan, V
   Wu, SPN
   Game, F
AF Chen, Pam
   Vilorio, Nalini Campillo
   Dhatariya, Ketan
   Jeffcoate, William
   Lobmann, Ralf
   Mcintosh, Caroline
   Piaggesi, Alberto
   Steinberg, John
   Vas, Prash
   Viswanathan, Vijay
   Wu, Stephanie
   Game, Fran
TI Effectiveness of interventions to enhance healing of chronic foot ulcers
   in diabetes: A systematic review
SO DIABETES-METABOLISM RESEARCH AND REVIEWS
LA English
DT Article
DE diabetic foot; systematic review; wound healing
ID HYPERBARIC-OXYGEN THERAPY; PRESSURE WOUND THERAPY; RANDOMIZED
   CONTROLLED-TRIAL; VACUUM-ASSISTED CLOSURE; PLATELET-RICH PLASMA;
   QUALITY-OF-LIFE; CONTROLLED CLINICAL-TRIAL; COLONY-STIMULATING FACTOR;
   EPIDERMAL-GROWTH-FACTOR; PLACEBO-CONTROLLED TRIAL
AB BackgroundIt is critical that interventions used to enhance the healing of chronic foot ulcers in diabetes are backed by high-quality evidence and cost-effectiveness. In previous years, the systematic review accompanying guidelines published by the International Working Group of the Diabetic Foot performed 4-yearly updates of previous searches, including trials of prospective, cross-sectional and case-control design.AimsDue to a need to re-evaluate older studies against newer standards of reporting and assessment of risk of bias, we performed a whole new search from conception, but limiting studies to randomised control trials only.Materials and MethodsFor this systematic review, we searched PubMed, Scopus and Web of Science databases for published studies on randomised control trials of interventions to enhance healing of diabetes-related foot ulcers. We only included trials comparing interventions to standard of care. Two independent reviewers selected articles for inclusion and assessed relevant outcomes as well as methodological quality.ResultsThe literature search identified 22,250 articles, of which 262 were selected for full text review across 10 categories of interventions. Overall, the certainty of evidence for a majority of wound healing interventions was low or very low, with moderate evidence existing for two interventions (sucrose-octasulfate and leucocyte, platelet and fibrin patch) and low quality evidence for a further four (hyperbaric oxygen, topical oxygen, placental derived products and negative pressure wound therapy). The majority of interventions had insufficient evidence.ConclusionOverall, the evidence to support any other intervention to enhance wound healing is lacking and further high-quality randomised control trials are encouraged.
C1 [Chen, Pam] Ramsay Healthcare Australia, Joondalup Hlth Campus, Joondalup, WA, Australia.
   [Chen, Pam] Univ Tasmania, Fac Hlth, Hobart, Tas, Australia.
   [Vilorio, Nalini Campillo] Plaza Salud Gen Hosp, Dept Diabetol, Diabetic Foot Unit, Santo Domingo, Dominican Rep.
   [Dhatariya, Ketan] Norfolk & Norwich Univ Hosp NHS Fdn Trust, Elsie Bertram Diabet Ctr, Norwich, England.
   [Dhatariya, Ketan] Univ East Anglia, Norwich Med Sch, Norwich, England.
   [Jeffcoate, William; Lobmann, Ralf] Klinikum Stuttgart, Clin Endocrinol Diabetol & Geriatr, Stuttgart, Germany.
   [Mcintosh, Caroline] Univ Galway, Sch Hlth Sci, Galway, Ireland.
   [Piaggesi, Alberto] Univ Pisa, Dept Med, Diabetic Foot Sect, Pisa, Italy.
   [Steinberg, John] Georgetown Univ, Sch Med, Washington, DC USA.
   [Vas, Prash] Kings Coll Hosp NHS Fdn Trust, London, England.
   [Viswanathan, Vijay] MV Hosp Diabet & M Prof Viswanathan Diabet Res Ctr, Chennai, India.
   [Wu, Stephanie] Rosalind Franklin Univ Med & Sci, Dr William M Scholl Coll Podiatr Med, N Chicago, IL USA.
   [Game, Fran] Univ Hosp Derby, Burton NHS Fdn Trust, Derby, England.
C3 University of Tasmania; Norfolk & Norwich University Hospitals NHS
   Foundation Trust; University of East Anglia; University of Stuttgart;
   University Stuttgart Hospital; Ollscoil na Gaillimhe-University of
   Galway; University of Pisa; Georgetown University; King's College
   Hospital NHS Foundation Trust; Rosalind Franklin University of Medicine
   & Science
RP Chen, PM (通讯作者)，Ramsay Healthcare Australia, Joondalup Hlth Campus, Joondalup, WA, Australia.; Chen, PM (通讯作者)，Univ Tasmania, Fac Hlth, Hobart, Tas, Australia.
EM chenp@ramsayhealth.com.au
OI Campillo-Vilorio, Nalini/0009-0009-8521-4262; Jeffcoate,
   William/0000-0002-1744-7576; McIntosh, Caroline/0000-0003-1801-9554;
   Game, Frances/0000-0002-5294-4789
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NR 278
TC 16
Z9 26
U1 2
U2 20
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1520-7552
EI 1520-7560
J9 DIABETES-METAB RES
JI Diabetes-Metab. Res. Rev.
PD MAR 20
PY 2024
VL 40
IS 3
AR e3786
DI 10.1002/dmrr.3786
PG 44
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA LO7B4
UT WOS:001187798700001
PM 38507616
OA hybrid
DA 2026-07-24
ER

PT J
AU Dissemond, J
   Körber, A
   Grabbe, S
AF Dissemond, J
   Körber, A
   Grabbe, S
TI Take of mesh grafts in chronic leg ulcer patients improves by
   vacuum-assisted closure device
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nurnberg, GERMANY
DE vacuum-assisted closure; leg ulcer; chronic wound; mesh graft;
   skin-graft
AB Vacuum-assisted closure (V.A.C.(R)) is an established therapeutic option in the management of acute and chronic granulating wounds. In recent years, little data has been published concerning skin graft transplantation and postoperative V.A.C.(R) therapy. We report a consecutive case series of 54 patients with chronic leg ulcer who received a total of 74 mesh grafts. A postoperative V.A.C.(R) therapy was performed in 28 mesh grafts, and 46 mesh grafts were treated with standard gauze therapy. In the V.A.C.(R) group, 92.9% grafts showed complete healing. In the treatment group without postoperative V.A.C.(R) therapy, 67.4% of the mesh grafts had taken. Differential analysis revealed a correlation in patients over 70 years of age or in patients suffering from diabetes mellitus or dermatoliposclerosis. Particularly patients with diabetes mellitus and of greater age exhibited improved take rates in the V.A.C.(R) group. The results of our study demonstrate for the first time the significant benefit of V.A.C.(R) therapy after mesh-graft-transplantation in chronic leg ulcer patients as evaluated in a clinical trial with a control group.
C1 Univ Klinikum Essen, Dermatol Klin & Poliklin, D-45122 Essen, Germany.
C3 University of Duisburg Essen
RP Dissemond, J (通讯作者)，Univ Klinikum Essen, Dermatol Klin & Poliklin, Hufelandstr 55, D-45122 Essen, Germany.
EM joachimdissemond@hotmail.com
RI Grabe, Stephan/AAJ-4578-2021; Dissemond, Joachim/AFG-0691-2022
CR Carson Stanley N, 2004, Ostomy Wound Manage, V50, P52
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NR 10
TC 2
Z9 2
U1 0
U2 1
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S165
EP S167
DI 10.1055/s-2006-921449
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 034DB
UT WOS:000236904100039
PM 16575672
DA 2026-07-24
ER

PT J
AU De Simone, B
   Sartelli, M
   Coccolini, F
   Ball, CG
   Brambillasca, P
   Chiarugi, M
   Campanile, FC
   Nita, G
   Corbella, D
   Leppaniemi, A
   Boschini, E
   Moore, EE
   Biffl, W
   Peitzmann, A
   Kluger, Y
   Sugrue, M
   Fraga, G
   Di Saverio, S
   Weber, D
   Sakakushev, B
   Chiara, O
   Abu-Zidan, FM
   ten Broek, R
   Kirkpatrick, AW
   Wani, I
   Coimbra, R
   Baiocchi, GL
   Kelly, MD
   Ansaloni, L
   Catena, F
AF De Simone, Belinda
   Sartelli, Massimo
   Coccolini, Federico
   Ball, Chad G.
   Brambillasca, Pietro
   Chiarugi, Massimo
   Campanile, Fabio Cesare
   Nita, Gabriela
   Corbella, Davide
   Leppaniemi, Ari
   Boschini, Elena
   Moore, Ernest E.
   Biffl, Walter
   Peitzmann, Andrew
   Kluger, Yoram
   Sugrue, Michael
   Fraga, Gustavo
   Di Saverio, Salomone
   Weber, Dieter
   Sakakushev, Boris
   Chiara, Osvaldo
   Abu-Zidan, Fikri M.
   ten Broek, Richard
   Kirkpatrick, Andrew W.
   Wani, Imtiaz
   Coimbra, Raul
   Baiocchi, Gian Luca
   Kelly, Micheal D.
   Ansaloni, Luca
   Catena, Fausto
TI Intraoperative surgical site infection control and prevention: a
   position paper and future addendum to WSES intra-abdominal infections
   guidelines
SO WORLD JOURNAL OF EMERGENCY SURGERY
LA English
DT Review
DE Emergency; Surgical site infection; Prevention; Intra-abdominal
   infection; Operating room
ID RANDOMIZED CONTROLLED-TRIAL; TRICLOSAN-COATED SUTURES; PRESSURE WOUND
   THERAPY; ABDOMINAL-WALL CLOSURE; SUPPLEMENTAL PERIOPERATIVE OXYGEN;
   SUBCUTANEOUS SUCTION DRAINS; VACUUM-ASSISTED CLOSURE; DELAYED PRIMARY
   CLOSURE; SKIN CLOSURE; GASTROINTESTINAL SURGERY
AB Background Surgical site infections (SSI) represent a considerable burden for healthcare systems. They are largely preventable and multiple interventions have been proposed over past years in an attempt to prevent SSI. We aim to provide a position paper on Operative Room (OR) prevention of SSI in patients presenting with intra-abdominal infection to be considered a future addendum to the well-known World Society of Emergency Surgery (WSES) Guidelines on the management of intra-abdominal infections. Methods The literature was searched for focused publications on SSI until March 2019. Critical analysis and grading of the literature has been performed by a working group of experts; the literature review and the statements were evaluated by a Steering Committee of the WSES. Results Wound protectors and antibacterial sutures seem to have effective roles to prevent SSI in intra-abdominal infections. The application of negative-pressure wound therapy in preventing SSI can be useful in reducing postoperative wound complications. It is important to pursue normothermia with the available resources in the intraoperative period to decrease SSI rate. The optimal knowledge of the pharmacokinetic/pharmacodynamic characteristics of antibiotics helps to decide when additional intraoperative antibiotic doses should be administered in patients with intra-abdominal infections undergoing emergency surgery to prevent SSI. Conclusions The current position paper offers an extensive overview of the available evidence regarding surgical site infection control and prevention in patients having intra-abdominal infections.
C1 [De Simone, Belinda] Azienda USL IRCSS Reggio Emilia, Dept Gen Surg, Guastalla Hosp, Via Donatori Sangue 1, I-42016 Guastalla, RE, Italy.
   [Sartelli, Massimo] Macerata Hosp, Dept Gen Surg, I-62100 Macerata, Italy.
   [Coccolini, Federico] Pisa Univ Hosp, Gen Emergency & Trauma Surg, I-56124 Pisa, Italy.
   [Ball, Chad G.] Univ Calgary, Dept Surg & Oncol Hepatobiliary & Pancreat Surg, Trauma & Acute Care Surg, Foothills Med Ctr, Calgary, AB T2N 2T9, Canada.
   [Brambillasca, Pietro; Corbella, Davide] Papa Giovanni XXIII Hosp, Anesthesia & Crit Care Dept, Pzza OMS 1, I-24128 Bergamo, Italy.
   [Chiarugi, Massimo] Cisanello Hosp, Emergency Surg Unit, Pisa, Italy.
   [Chiarugi, Massimo] Cisanello Hosp, Ctr Trauma, Pisa, Italy.
   [Campanile, Fabio Cesare] Osped Andosilla, Fabio Cesare Campanile, Civita Castellana, Italy.
   [Nita, Gabriela] Castelnuovo NeMonti Hosp, Unit Gen Surg, AUSL, Reggio Emilia, Italy.
   [Leppaniemi, Ari] Univ Helsinki, Abdominal Ctr, Meilahti Hosp, Helsinki, Finland.
   [Boschini, Elena] Papa Giovanni XXIII Hosp, Med Lib, Pzza OMS 1, I-24128 Bergamo, Italy.
   [Moore, Ernest E.] Denver Hlth, Ernest E Moore Shock Trauma Ctr, Denver, CO USA.
   [Moore, Ernest E.] Univ Colorado, Denver, CO 80202 USA.
   [Biffl, Walter] Scripps Mem Hosp, Trauma & Acute Care Surg, La Jolla, CA USA.
   [Peitzmann, Andrew] Univ Pittsburgh, Sch Med, Dept Surg, Pittsburgh, PA USA.
   [Kluger, Yoram] Rambam Hlth Care Campus, Div Gen Surg, Haifa, Israel.
   [Sugrue, Michael] Letterkenny Univ Hosp, Dept Surg, Letterkenny, Ireland.
   [Sugrue, Michael] Donegal Clin Res Acad, Letterkenny, Ireland.
   [Fraga, Gustavo] Univ Estadual Campinas, Sch Med Sci, Div Trauma Surg, Campinas, SP, Brazil.
   [Di Saverio, Salomone] Cambridge Univ Hosp NHS Fdn Trust, Cambridge, England.
   [Weber, Dieter] Royal Perth Hosp, Trauma & Gen Surg, Perth, WA, Australia.
   [Sakakushev, Boris] Univ Hosp St George First, Clin Gen Surg, Plovdiv, Bulgaria.
   [Chiara, Osvaldo] State Univ Milan, Acute Care Surg Niguarda Hosp, Milan, Italy.
   [Abu-Zidan, Fikri M.] UAE Univ, Coll Med & Hlth Sci, Dept Surg, Al Ain, U Arab Emirates.
   [ten Broek, Richard] Radboud Univ Nijmegen, Nijmegen, Netherlands.
   [Kirkpatrick, Andrew W.] Foothills Med Ctr, Calgary, AB, Canada.
   [Kirkpatrick, Andrew W.] Univ Calgary, Calgary, AB, Canada.
   [Wani, Imtiaz] Sheri Kashmir Inst Med Sci, Dept Surg, Srinagar, India.
   [Coimbra, Raul] UC San Diego Med Ctr, Dept Surg, San Diego, CA USA.
   [Baiocchi, Gian Luca] Univ Brescia, Dept Surg, Brescia, Italy.
   [Kelly, Micheal D.] Albury Hosp, Dept Gen Surg, Albury, NSW 2640, Australia.
   [Ansaloni, Luca] Bufalini Hosp, Dept Emergency & Trauma Surg, I-47521 Cesena, Italy.
   [Catena, Fausto] Univ Hosp Parma, Dept Emergency & Trauma Surg, I-43100 Parma, Italy.
C3 University of Pisa; Azienda Ospedaliero Universitaria Pisana; University
   of Calgary; University Calgary Hospital; ASST Papa Giovanni XXIII;
   University of Helsinki; Helsinki University Central Hospital; ASST Papa
   Giovanni XXIII; Denver Health Medical Center; University of Colorado
   System; University of Colorado Denver; Pennsylvania Commonwealth System
   of Higher Education (PCSHE); University of Pittsburgh; Technion Israel
   Institute of Technology; Rambam Health Care Campus; Universidade
   Estadual de Campinas; University of Cambridge; East Metropolitan Health
   Service; Royal Perth Hospital; University of Milan; United Arab Emirates
   University; Radboud University Nijmegen; University of Calgary;
   University Calgary Hospital; University of Calgary; Sher-i-Kashmir
   Institute of Medical Sciences; University of California System;
   University of California San Diego; University of Brescia; University of
   Parma; University Hospital of Parma
RP De Simone, B (通讯作者)，Azienda USL IRCSS Reggio Emilia, Dept Gen Surg, Guastalla Hosp, Via Donatori Sangue 1, I-42016 Guastalla, RE, Italy.
EM desimone.belinda@gmail.com
RI Leppäniemi, Ari/GQZ-7991-2022; De Simone, Belinda/AAD-5646-2019;
   /AAD-7440-2020; Broek, Richard/M-9038-2016; Abu-Zidan,
   Fikri/GWE-2835-2022; Sakakushev, Boris/MGV-4913-2025; Chiarugi,
   Massimo/ABQ-7280-2022; Di Saverio, Salomone/G-1437-2012; Ansaloni,
   Luca/AAP-9134-2020; Ansaloni, Luca/AAJ-6507-2020; Coimbra,
   Raul/AAP-3019-2020; Campanile, Fabio Cesare/G-2831-2012; chiara,
   osvaldo/R-6151-2018
OI BAIOCCHI, Gian Luca/0000-0003-2402-2178; Sakakushev,
   Boris/0000-0001-8399-0115; Chiarugi, Massimo/0000-0001-6905-2499; Di
   Saverio, Salomone/0000-0001-5685-5022; Ansaloni,
   Luca/0000-0001-6427-0307; Kong, Victor/0000-0003-2291-2572; Ansaloni,
   Luca/0000-0001-6427-0307; Coimbra, Raul/0000-0002-3759-6851; Campanile,
   Fabio Cesare/0000-0003-3830-634X; chiara, osvaldo/0000-0003-2409-2109
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NR 136
TC 84
Z9 91
U1 1
U2 15
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-7922
J9 WORLD J EMERG SURG
JI World J. Emerg. Surg.
PD FEB 10
PY 2020
VL 15
IS 1
AR 10
DI 10.1186/s13017-020-0288-4
PG 23
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA KT5VO
UT WOS:000519082800001
PM 32041636
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Schmelzle, M
   Alldinger, I
   Matthaei, H
   Aydin, F
   Wallert, I
   Eisenberger, CF
   Esch, JSA
   Dizdar, L
   Topp, SA
   Yang, Q
   Knoefel, WT
AF Schmelzle, Moritz
   Alldinger, Ingo
   Matthaei, Hanno
   Aydin, Feride
   Wallert, Ingo
   Eisenberger, Claus F.
   Esch, Jan Schulte Am, II
   Dizdar, Levent
   Topp, Stefan A.
   Yang, Qin
   Knoefel, Wolfram T.
TI Long-Term Vacuum-Assisted Closure in Open Abdomen due to Secondary
   Peritonitis: A Retrospective Evaluation of a Selected Group of Patients
SO DIGESTIVE SURGERY
LA English
DT Article
DE Vacuum-assisted closure therapy; Open abdomen; Peritonitis
ID FASCIAL CLOSURE; ENTEROCUTANEOUS FISTULA; ABDOMINAL CLOSURE; VENTRAL
   HERNIA; WOUND CLOSURE; TRAUMA; EXPERIENCE; MANAGEMENT
AB Background/Aims: Vacuum-assisted closure (VAC) leads to a high fascial closure rate in open abdomen within the first week of treatment. However, little data exist on the role of long-term VAC treatment in patients with peritonitis, where fascial closure cannot be accomplished within the first days. Methods: We reviewed the medical records of 49 patients with open abdomen for more than 7 days due to secondary peritonitis, who underwent a VAC-treatment. Nonparametric analysis was performed using chi(2) test or Fisher's exact test. Results: Fascial closure could be accomplished in only 11 patients (22%), whereas complications occurred in 43 patients (88%). Re-explorations after starting VAC were associated with the occurrence of enterocutaneous fistula (p < 0.001) and were also of prognostic value regarding the rate of fascial closure (p = 0.033). Conclusions: If fascial closure cannot be accomplished within the first days, patients show a dramatically lower fascial closure and an increased complication rate with VAC. Further studies are needed to evaluate whether this subgroup really benefits from VAC. Copyright (C) 2010 S. Karger AG, Basel
C1 [Schmelzle, Moritz; Alldinger, Ingo; Matthaei, Hanno; Aydin, Feride; Wallert, Ingo; Eisenberger, Claus F.; Esch, Jan Schulte Am, II; Dizdar, Levent; Topp, Stefan A.; Knoefel, Wolfram T.] Univ Hosp Dusseldorf, Dept Surg, DE-40225 Dusseldorf, Germany.
   [Yang, Qin] Univ Dusseldorf, Fac Med, Coordinat Ctr Clin Trials, Dusseldorf, Germany.
C3 Heinrich Heine University Dusseldorf; Heinrich Heine University
   Dusseldorf Hospital; Heinrich Heine University Dusseldorf
RP Knoefel, WT (通讯作者)，Univ Hosp Dusseldorf, Dept Surg, Moorenstr 5, DE-40225 Dusseldorf, Germany.
EM knoefel@med.uni-duesseldorf.de
RI Esch, Jan/AAL-9904-2021
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NR 21
TC 27
Z9 34
U1 0
U2 2
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 0253-4886
EI 1421-9883
J9 DIGEST SURG
JI Dig. Surg.
PY 2010
VL 27
IS 4
BP 272
EP 278
DI 10.1159/000314609
PG 7
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 646DT
UT WOS:000281517500005
PM 20664203
DA 2026-07-24
ER

PT J
AU Wang, WY
   Pan, ZY
   Hu, X
   Li, ZH
   Zhao, Y
   Yu, AX
AF Wang, Weiyang
   Pan, Zhenyu
   Hu, Xiang
   Li, Zonghuan
   Zhao, Yong
   Yu, Ai-Xi
TI Vacuum-assisted closure increases ICAM-1, MIF, VEGF and collagen I
   expression in wound therapy
SO EXPERIMENTAL AND THERAPEUTIC MEDICINE
LA English
DT Article
DE severe traumatic wound; vacuum-assisted closure; intercellular adhesion
   molecule-1; migration inhibitory factor; collagen I
ID FIBROBLAST-GROWTH-FACTOR; MIGRATION INHIBITORY FACTOR; L-SELECTIN;
   TISSUE; METALLOPROTEINASES; FOUNDATION; MATRIX; DEVICE; MICE
AB Severe traumatic wounds are challenging to manage during surgery. The introduction of vacuum-assisted closure (VAC) is a breakthrough in wound management. The aim of the present study was to investigate the effect of VAC on cytokines in wounds during the management of severe traumatic wounds following initial debridement. VAC and conventional wound care (CWC) were independently applied to severe traumatic wounds on pigs. The expression levels of intercellular adhesion molecule-1 (ICAM-1), migration inhibitory factor (MIF), vascular endothelial growth factor (VEGF), basic fibroblast growth factor, collagen I and human fibroblast collagenase 1 were detected by quantitative polymerase chain reaction and western blotting. VAC significantly increased the expression of ICAM-1, MIF, VEGF and collagen I compared with that induced by CWC at the protein and mRNA levels. Therefore, the results of the present study indicate that VAC therapy is an effective method for treating severe traumatic wounds, as it increases the expression of cytokines in wounds. VAC significantly increases the expression of ICAM-1, MIF, VEGF and collagen I to manage severe traumatic wounds.
C1 [Wang, Weiyang; Pan, Zhenyu; Hu, Xiang; Li, Zonghuan; Zhao, Yong; Yu, Ai-Xi] Wuhan Univ, Zhongnan Hosp, Dept Microorthoped, Wuhan 430071, Hubei, Peoples R China.
C3 Wuhan University
RP Yu, AX (通讯作者)，Wuhan Univ, Zhongnan Hosp, Dept Microorthoped, 169 Donghu Rd, Wuhan 430071, Hubei, Peoples R China.
EM yuaixi666@hotmail.com
OI Yu, Aixi/0000-0002-3751-0894
FU National Natural Science Funds of China [81171713]
FX The authors thank Wuhan VSD Medical Science & Technology, Co., Ltd.
   (Wuhan, China) for supplying the vacuum pump. The study was financed by
   a grant from the National Natural Science Funds of China (no. 81171713).
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Z9 24
U1 0
U2 15
PU SPANDIDOS PUBL LTD
PI ATHENS
PA POB 18179, ATHENS, 116 10, GREECE
SN 1792-0981
EI 1792-1015
J9 EXP THER MED
JI Exp. Ther. Med.
PD MAY
PY 2014
VL 7
IS 5
BP 1221
EP 1226
DI 10.3892/etm.2014.1567
PG 6
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA AJ3HS
UT WOS:000337557700029
PM 24940415
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Lindstedt, S
   Malmsjö, M
   Ingemansson, R
AF Lindstedt, Sandra
   Malmsjo, Malin
   Ingemansson, Richard
TI C-reactive protein and leucocyte counts drop faster using the
   HeartShield® device in patients with DSWI
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE C-reactive protein; Deep sternal wound infection; HeartShield (R);
   Negative pressure therapy; Right ventricular rupture
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; PREVENT HEART RUPTURE;
   POSTSTERNOTOMY MEDIASTINITIS; CARDIAC-SURGERY; RIGID BARRIER; INFECTION;
   EXPERIENCE; ALGORITHM
AB Right ventricular heart rupture is a devastating complication associated with negative pressure wound therapy (NPWT) in cardiac surgery. The use of a rigid barrier disc (HeartShield) has been suggested to offer protection against this lethal complication by preventing the heart from being drawn up by the negative pressure and damaged by the sharp sternum bone edges. Seven patients treated with conventional NPWT and seven patients treated with NPWT with a protective barrier disc (HeartShield) were compared with regard to bacterial clearance and infection parameters including C-reactive protein levels and leucocyte counts. C-reactive protein levels and leucocyte counts dropped faster and bacterial clearance occurred earlier in the HeartShield (R) group compared with the conventional NPWT group. Negative biopsy cultures were shown after 31 +/- 04 NPWT dressing changes in the HeartShield group, and after 54 +/- 06 NPWT dressing changes in the conventional NPWT group (P<0001). All patients were followed up with clinical check-up after 3months. None of the patients in the HeartShield group had any signs of reinfection such as deep sternal wound infection (DSWI) or sternal fistulas, whereas in the conventional NPWT group, two patients had signs of sternal fistulas that demanded hospitalisation. HeartShield hinders the right ventricle to come into contact with the sharp sternal edges during NPWT and thereby protects from heart damage. This study shows that using HeartShield is beneficial in treating patients with DSWI. Improved wound healing by HeartShield may be a result of the efficient drainage of wound effluents from the thoracic cavity.
C1 [Lindstedt, Sandra; Ingemansson, Richard] Lund Univ, Dept Cardiothorac Surg, Lund, Sweden.
   [Lindstedt, Sandra; Malmsjo, Malin; Ingemansson, Richard] Skane Univ Hosp, Lund, Sweden.
   [Malmsjo, Malin] Lund Univ, Dept Ophthalmol, Lund, Sweden.
C3 Lund University; Lund University; Skane University Hospital; Lund
   University
RP Lindstedt, S (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, Heart & Lung Ctr, SE-22185 Lund, Sweden.
EM sandra.lindstedt@med.lu.se
RI ; Lindstedt, Sandra/AEM-2892-2022
OI Maljö, Malin/0000-0001-9849-9599; Lindstedt, Sandra/0000-0003-4484-6473;
   Ingemansson, Richard/0000-0001-7623-8953
CR [Anonymous], 2009, SER COMPL ASS NEG PR
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NR 28
TC 2
Z9 2
U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2015
VL 12
IS 2
BP 189
EP 194
DI 10.1111/iwj.12079
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CE2EI
UT WOS:000351626400013
PM 23651118
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Mark, KS
   Alger, L
   Terplan, M
AF Mark, Katrina S.
   Alger, Lindsay
   Terplan, Mishka
TI Incisional Negative Pressure Therapy to Prevent Wound Complications
   Following Cesarean Section in Morbidly Obese Women: A Pilot Study
SO SURGICAL INNOVATION
LA English
DT Article
DE obesity; cesarean section; wound complication; negative pressure therapy
ID VACUUM-ASSISTED CLOSURE; RISK-FACTORS; INFECTIONS; MANAGEMENT
AB Objective. We sought to evaluate the efficacy of incisional negative pressure therapy in decreasing postoperative wound complications when placed prophylactically over clean, closed incisions following cesarean section in obese patients. Study design. This was a retrospective cohort study comparing rates of wound complications following cesarean sections in morbidly obese women prior to and following the institution of standard use of prophylactic incisional negative pressure therapy. All women with a body mass index greater than 45 kg/m(2) undergoing cesarean section in a 2-year period in a single institution were included. The exposure was incisional negative pressure therapy, which began in September 2009, versus standard wound dressing used in the previous year. The main outcome was wound complication identified by ICD-9 codes. Demographic and wound outcomes were compared with chi(2) and t tests. Stata version 11.0 was used for all analysis. Results. A total of 63 women met the inclusion criteria, 21 of whom received negative pressure wound therapy. The historical comparison and exposure groups were similar in all characteristics studied with the exceptions of length of surgery (64 vs 76 minutes, P =.03), length of labor (78 vs 261 minutes, P =.02), scheduled versus nonscheduled (77% vs 52%, P =.04), and mean age (29.5 vs 26.1 years, P =.04), respectively. There were 5 wound complications in the control group (10.4%) and none (0%) in the study group (P =.15). Conclusions. This pilot study suggests a decrease in wound complications in morbidly obese women receiving incisional negative pressure therapy following cesarean section.
C1 [Mark, Katrina S.; Alger, Lindsay; Terplan, Mishka] Univ Maryland, Baltimore, MD 21201 USA.
C3 University System of Maryland; University of Maryland Baltimore
RP Mark, KS (通讯作者)，Univ Maryland, Dept Obstet Gynecol & Reprod Sci, 11 S Paca St,Suite 400, Baltimore, MD 21201 USA.
EM kmark@fpi.umaryland.edu
OI Mark, Katrina/0000-0001-5127-2936
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NR 25
TC 46
Z9 48
U1 0
U2 8
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1553-3506
EI 1553-3514
J9 SURG INNOV
JI Surg. Innov.
PD AUG
PY 2014
VL 21
IS 4
BP 345
EP 349
DI 10.1177/1553350613503736
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AN6PD
UT WOS:000340716600001
PM 24056202
DA 2026-07-24
ER

PT J
AU Simek, M
   Hajek, R
   Fluger, I
   Molitor, M
   Grulichova, J
   Langova, K
   Tobbia, P
   Nemec, P
   Zalesak, B
   Lonsky, V
AF Simek, M.
   Hajek, R.
   Fluger, I.
   Molitor, M.
   Grulichova, J.
   Langova, K.
   Tobbia, P.
   Nemec, P.
   Zalesak, B.
   Lonsky, V.
TI Superiority of topical negative pressure over closed irrigation therapy
   of deep sternal wound infection in cardiac surgery
SO JOURNAL OF CARDIOVASCULAR SURGERY
LA English
DT Article; Proceedings Paper
CT 58th Annual Meeting of the Scandinavian-Association-for-Thoracic-Surgery
   (SATS)
CY AUG 20-22, 2009
CL Stockholm, SWEDEN
SP Scandinavian Assoc Thorac Surg (SATS)
DE Wound infection; Negative-pressure wound therapy; Cardiac surgical
   procedures, complications
ID VACUUM-ASSISTED CLOSURE; PERISTERNAL THORACIC WALL; LONG-TERM SURVIVAL;
   POSTSTERNOTOMY MEDIASTINITIS; BLOOD-FLOW; STERNOTOMY; IMPACT; MANAGEMENT
AB Aim. We sought to compare clinical outcomes, in-hospital mortality and 1-year survival of two different treatment modalities of deep sternal wound infection, topical negative pressure and the closed irrigation therapy.
   Methods. Retrospective analysis of 66 consecutive patients treated for deep sternal infection at our institution. A total of 28 patients (February 2002 through September 2004) underwent primarily closed irrigation therapy, and 34 patients (November 2004 through December 2007) had the application of topical negative pressure. Four patients (July 2004 through December 2004) who underwent a combination of both strategies were excluded from the study. Clinical and wound care outcomes were compared, focusing on therapeutic failure rate, in-hospital stay and the 1-year mortality of both treatment strategies.
   Results. Topical negative pressure was associated with a significantly lower failure rate of the primary therapy (P<0.05), shortening of the intensive care unit stay (P<0.001), a particular decrease in the in-hospital stay (P<0.05) and the 1-year mortality (P<0.05) in comparison with closed irrigation therapy. Comparable overall length of the therapy, in-hospital stay and the risk of wire-related fistulas after chest reconstruction were found.
   Conclusion. Topical negative pressure is a superior method of treatment for deep sternal wound infection, which is based on lower therapeutic failure rate, significant decrease in-hospital stay, and the decrease of the 1-year mortality rate, compared with primarily applied closed irrigation.
C1 [Simek, M.; Hajek, R.; Fluger, I.; Grulichova, J.; Tobbia, P.; Nemec, P.; Lonsky, V.] Univ Hosp & Palacky Univ, Fac Med, Dept Cardiac Surg, Olomouc 77520, Czech Republic.
   [Molitor, M.; Zalesak, B.] Univ Hosp & Palacky Univ, Fac Med, Dept Plast & Reconstruct Surg, Olomouc 77520, Czech Republic.
   [Langova, K.] Univ Hosp & Palacky Univ, Fac Med, Inst Med Biophys, Olomouc 77520, Czech Republic.
C3 University Hospital Olomouc; Palacky University Olomouc; Palacky
   University Olomouc; University Hospital Olomouc; University Hospital
   Olomouc; Palacky University Olomouc
RP Simek, M (通讯作者)，Univ Hosp & Palacky Univ, Fac Med, Dept Cardiac Surg, IP Pavlova 6, Olomouc 77520, Czech Republic.
EM martin.simek@c-mail.cz
RI ; Molitor, Martin/AAF-8445-2021; Hajek, Roman/AAB-4232-2020
OI Šimek, Martin/0000-0001-5377-2096; Molitor, Martin/0000-0003-3843-9150; 
CR Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
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   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
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NR 25
TC 15
Z9 18
U1 0
U2 12
PU EDIZIONI MINERVA MEDICA
PI TURIN
PA CORSO BRAMANTE 83-85 INT JOURNALS DEPT., 10126 TURIN, ITALY
SN 0021-9509
EI 1827-191X
J9 J CARDIOVASC SURG
JI J. Cardiovasc. Surg.
PD FEB
PY 2012
VL 53
IS 1
BP 113
EP 120
PG 8
WC Cardiac & Cardiovascular Systems; Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Cardiovascular System & Cardiology; Surgery
GA 905KH
UT WOS:000301270600016
PM 22231537
DA 2026-07-24
ER

PT J
AU Reese, MW
   Hogge, RL
   Roess, BJ
   Hepner, JM
   Luke, RD
   Rendel, RE
   Kabir, IK
   Nguyen, TM
   Snyder, KN
   Heaton, JA
   Martyak, MT
AF Reese, Miles W.
   Hogge, Raymond L.
   Roess, Brendan J.
   Hepner, John M.
   Luke, Robert D.
   Rendel, Ricardo E.
   Kabir, Ishraq K.
   Nguyen, Tuan M.
   Snyder, Kristen N.
   Heaton, Julia A.
   Martyak, Michael T.
TI The Implementation of Incisional Negative Pressure Therapy in Trauma
   Laparotomies Leads to Fewer Open Wounds at Discharge
SO AMERICAN SURGEON
LA English
DT Article
DE surgical infection; wound healing; trauma
ID SURGICAL SITE INFECTION; VACUUM-ASSISTED CLOSURE
AB Background: Surgical site infections (SSIs) tend to be higher in emergent trauma cases. To combat this increased risk, the skin is often left open and allowed to heal by secondary intention. We sought to investigate the effect of the implementation of incisional negative pressure wound therapy (iNPWT) in trauma laparotomies. Methods: A single-institution retrospective chart review was performed of trauma patients receiving an emergent exploratory laparotomy between 2015 and 2022. Patients with class II and III wounds were included. The primary outcome was open wound at discharge between the pre-iNPWT and post-iNPWT implementation. The secondary outcome was development of superficial SSI in closed wounds. Results: 260 patients, 111 pre-iNPWT and 149 post-iNPWT implementation, were included. The proportion of patients who were discharged with an open wound in the pre-iNPWT group was 52.3% vs 18.8% in the post-iNPWT group, P = <.001. The proportion of patients with closed wounds who developed a superficial SSI in the pre-iNPWT group was 12.1%, 8 of 66, vs 5.9%, 8 of 135, in the post-iNPWT group, P = .13. The proportion of patients with closed class III wounds who developed a superficial SSI was 14.0%, 7 of 50, vs 5.0%, 6 of 119, in the post-iNPWT group, P = .046. Conclusion: Our study identified a decrease in the number of patients who were discharged with an open wound after the implementation of iNPWT without an increase in SSIs. A decrease in SSIs in class III wounds closed with iNPWT was also observed.
C1 [Reese, Miles W.; Hogge, Raymond L.; Roess, Brendan J.; Hepner, John M.; Luke, Robert D.; Rendel, Ricardo E.; Kabir, Ishraq K.; Nguyen, Tuan M.; Snyder, Kristen N.; Heaton, Julia A.; Martyak, Michael T.] Old Dominion Univ, Eastern Virginia Med Sch, Dept Surg, Macon & Joan Brock Virginia Hlth Sci, 825 Fairfax Ave 610, Norfolk, VA 23507 USA.
C3 Old Dominion University; Eastern Virginia Medical School
RP Reese, MW (通讯作者)，Old Dominion Univ, Eastern Virginia Med Sch, Dept Surg, Macon & Joan Brock Virginia Hlth Sci, 825 Fairfax Ave 610, Norfolk, VA 23507 USA.
EM reesemw@evms.edu
OI Hogge, Raymond/0000-0002-4176-9209
CR 3M Health Care, 2019, PREVENA INCISION MAN
   Acker A, 2018, J SURG RES, V232, P450, DOI 10.1016/j.jss.2018.05.083
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   Chung JNC, 2021, SURGERY, V170, P1568, DOI 10.1016/j.surg.2021.04.009
   Coccolini F, 2023, WORLD J EMERG SURG, V18, DOI 10.1186/s13017-023-00509-4
   Cull JD, 2023, AM SURGEON, V89, P2785, DOI 10.1177/00031348211054522
   Durbin S, 2019, J SURG RES, V243, P496, DOI 10.1016/j.jss.2019.06.101
   Elmonim AMA., 2022, EGYPTIAN JOF SURG, V40, P1013, DOI [10.4103/ejs.ejs17621, DOI 10.4103/EJS.EJS17621]
   Gomoll AH, 2006, J ORTHOP TRAUMA, V20, P705, DOI 10.1097/01.bot.0000211159.98239.d2
   Isbell KD, 2021, SURG INFECT, V22, P697, DOI 10.1089/sur.2020.242
   Kabir I, 2023, AM SURGEON, V89, P1908, DOI 10.1177/00031348211054529
   Meyer J, 2023, WORLD J SURG, V47, P1464, DOI 10.1007/s00268-023-06908-7
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   National Healthcare Safety Network (NHSN), 2025, SURG SITE INFECT EVE
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
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NR 18
TC 1
Z9 1
U1 0
U2 0
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0003-1348
EI 1555-9823
J9 AM SURGEON
JI Am. Surg.
PD JUL
PY 2025
VL 91
IS 7
BP 1123
EP 1128
DI 10.1177/00031348251339700
EA MAY 2025
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 3TL4F
UT WOS:001494727100001
PM 40401823
DA 2026-07-24
ER

PT J
AU Willy, C
   Agarwal, A
   Andersen, CA
   De Santis, G
   Gabriel, A
   Grauhan, O
   Guerra, OM
   Lipsky, BA
   Malas, MB
   Mathiesen, LL
   Singh, DP
   Reddy, VS
AF Willy, Christian
   Agarwal, Animesh
   Andersen, Charles A.
   De Santis, Giorgio
   Gabriel, Allen
   Grauhan, Onnen
   Guerra, Omar M.
   Lipsky, Benjamin A.
   Malas, Mahmoud B.
   Mathiesen, Lars L.
   Singh, Devinder P.
   Reddy, V. Sreenath
TI Closed incision negative pressure therapy: international
   multidisciplinary consensus recommendations
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Consensus recommendation; Negative pressure therapy; Surgical incision
   management; Surgical site infection
ID SURGICAL-SITE INFECTION; VACUUM-ASSISTED CLOSURE; HIGH-RISK PATIENTS;
   WOUND THERAPY; MANAGEMENT-SYSTEM; CARDIAC-SURGERY; VASCULAR-SURGERY;
   CESAREAN-SECTION; MULTIVARIATE-ANALYSIS; GENERAL-SURGERY
AB Surgical site occurrences (SSOs) affect up to or over 25% of patients undergoing operative procedures, with the subset of surgical site infections (SSIs) being the most common. Commercially available closed incision negative pressure therapy (ciNPT) may offer surgeons an additional option to manage clean, closed surgical incisions. We conducted an extensive literature search for studies describing ciNPT use and assembled a diverse panel of experts to create consensus recommendations for when using ciNPT may be appropriate. A literature search of MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials using key words ' prevention ', ' negative pressure wound therapy (NPWT)', ' active incisional management ', ' incisional vacuum therapy ', ' incisional NPWT ', ' incisional wound VAC ', ' closed incisional NPWT ', ' wound infection ', and ' SSIs ' identified peer-reviewed studies published from 2000 to 2015. During a multidisciplinary consensus meeting, the 12 experts reviewed the literature, presented their own ciNPT experiences, identified risk factors for SSOs and developed comprehensive consensus recommendations. A total of 100 publications satisfied the search requirements for ciNPT use. A majority presented data supporting ciNPT use. Numerous publications reported SSI risk factors, with the most common including obesity (body mass index >= 30 kg/m(2)); diabetes mellitus; tobacco use; or prolonged surgical time. We recommend that the surgeon assess the individual patient's risk factors and surgical risks. Surgeons should consider using ciNPT for patients at high risk for developing SSOs or who are undergoing a high-risk procedure or a procedure that would have highly morbid consequences if an SSI occurred.
C1 [Willy, Christian] Bundeswehr Hosp Berlin, Res & Treatment Ctr Complex Combat Injuries, Wound Ctr Berlin, Dept Traumatol & Orthopaed Sept & Reconstruct Sur, Berlin, Germany.
   [Agarwal, Animesh] Univ Texas Hlth Sci Ctr San Antonio, Div Orthopaed Traumatol, San Antonio, TX 78229 USA.
   [Andersen, Charles A.] Madigan Army Med Ctr, Vascu Endovascu Limb Preservat Surg Serv, Tacoma, WA 98431 USA.
   [De Santis, Giorgio] Univ Modena & Reggio Emilia, Plast Reconstruct Microvascu & Aesthet Surg, Modena, Italy.
   [Gabriel, Allen] Peacehealth Med Grp, Plast Surg, Vancouver, WA USA.
   [Grauhan, Onnen] Deutsch Herzzentrum Berlin, Dept Cardiothorac & Vasc Surg, Berlin, Germany.
   [Guerra, Omar M.] Surg Suburban Surg Associates, St Louis, MO USA.
   [Lipsky, Benjamin A.] Univ Oxford, Div Med Sci, Oxford, England.
   [Malas, Mahmoud B.] Johns Hopkins Univ, Sch Med, Dept Surg, Baltimore, MD USA.
   [Mathiesen, Lars L.] Aalborg Univ Hosp, Dept Orthopaed Surg, Aalborg, Denmark.
   [Singh, Devinder P.] Anne Arundel Med Ctr, Div Plast Surg, Annapolis, MD USA.
   [Reddy, V. Sreenath] Centennial Heart & Vasc Ctr, TriStar CV Surg, Nashville, TN USA.
C3 University of Texas System; University of Texas at San Antonio; Madigan
   Army Medical Center; Universita di Modena e Reggio Emilia; German Heart
   Center Berlin; University of Oxford; Johns Hopkins University; Aalborg
   University; Aalborg University Hospital
RP Willy, C (通讯作者)，Bundeswehrkrankenhaus Berlin, Dept Traumatol & Orthopaed Sept & Reconstruct Sur, Scharnhorststr 13, D-10115 Berlin, Germany.
EM ChristianWilly@bundeswehr.org
RI Agarwal, Animesh/AAG-5725-2020; Lipsky, Benjamin A/IZE-0823-2023; De
   Santis, Giorgio/P-9027-2016; Gabriel, Allen/AFK-3548-2022; Singh,
   Devinder/AAN-4716-2021
OI Agarwal, Animesh/0000-0003-3287-3052; Lipsky, Benjamin
   A/0000-0001-9886-5114; 
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NR 121
TC 170
Z9 197
U1 0
U2 19
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2017
VL 14
IS 2
BP 385
EP 398
DI 10.1111/iwj.12612
PG 14
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA EQ4SH
UT WOS:000398068200013
PM 27170231
OA Green Accepted, Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Oh, BH
   Lee, SH
   Nam, KA
   Lee, HB
   Chung, KY
AF Oh, B. H.
   Lee, S. H.
   Nam, K. A.
   Lee, H. B.
   Chung, K. Y.
TI Comparison of negative pressure wound therapy and secondary intention
   healing after excision of acral lentiginous melanoma on the foot
SO BRITISH JOURNAL OF DERMATOLOGY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; GROWTH-FACTORS; SKIN; MECHANISM
AB Background Melanoma in dark-skinned individuals often develops in an acral lentiginous fashion on the foot and wide excision usually results in a substantial defect. Various repair methods, including free flap, full-thickness skin graft and secondary intention healing (SIH), are used to repair these defects. Recently, use of negative pressure wound treatment (NPWT) has been shown to accelerate wound healing in different types of wound.
   Objectives To compare the functional and cosmetic results of NPWT and SIH in patients who underwent wide excision of melanomas on the foot.
   Methods The wound defects of 22 patients after wide excision of melanoma on the foot were treated using SIH (n = 13) or NPWT (n = 9).
   Results There was no significant difference in time to complete wound healing between the two groups. However, evaluation using the Vancouver Burn Scar Assessment Scale at the time of complete healing showed that the mean score of the NPWT group was significantly lower than that of the SIH group. The NPWT group also had significantly better results than the SIH group in terms of total score, vascularity and height of the scars. As for complications, no wound infection was encountered in the NPWT group, whereas eight of the 13 patients in SIH group had wound infections during the course of treatment despite frequent and meticulous aseptic dressing changes.
   Conclusions These results show that, despite the drawback of rather prolonged healing time, NPWT is an excellent therapeutic option for wounds after wide excision of melanoma on the foot, with acceptable functional and cosmetic outcomes.
C1 [Oh, B. H.; Lee, S. H.; Nam, K. A.] Yonsei Univ, Coll Med, Dept Dermatol, Severance Hosp,Cutaneous Biol Res Inst, Seoul, South Korea.
   [Lee, H. B.] Hallym Univ, Kangnam Sacred Heart Hosp, Dept Plast Surg, Seoul, South Korea.
   [Chung, K. Y.] Yonsei Univ, Coll Med, Brain Korea Project Med Sci 21, Dept Dermatol,Severance Hosp,Cutaneous Biol Res I, Seoul, South Korea.
C3 Yonsei University; Severance Hospital; Yonsei University Health System;
   Hallym University; Yonsei University; Severance Hospital; Yonsei
   University Health System
RP Chung, KY (通讯作者)，Yonsei Univ, Coll Med, Brain Korea Project Med Sci 21, Dept Dermatol,Severance Hosp,Cutaneous Biol Res I, Seoul, South Korea.
EM kychung@yuhs.ac
RI kyung ae, nam/HNP-9338-2023; Oh, Byung Ho/HLQ-2899-2023
OI Chung, Kee Yang/0000-0003-3257-0297; Oh, Byung Ho/0000-0001-9575-5665
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NR 29
TC 26
Z9 31
U1 0
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0007-0963
EI 1365-2133
J9 BRIT J DERMATOL
JI Br. J. Dermatol.
PD FEB
PY 2013
VL 168
IS 2
BP 333
EP 338
DI 10.1111/bjd.12099
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 083NG
UT WOS:000314470600019
PM 23362968
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Thompson, JT
   Marks, MW
AF Thompson, James T.
   Marks, Malcolm W.
TI Negative pressure wound therapy
SO CLINICS IN PLASTIC SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED CONTROLLED-TRIAL; SOFT-TISSUE
   INJURIES; SECURING SKIN-GRAFTS; SUBATMOSPHERIC PRESSURE; FASCIAL
   CLOSURE; OPEN ABDOMEN; SWINE MODEL; MANAGEMENT; DEVICE
AB NPWT has proven to be a revolutionary breakthrough in wound management. Wounds that previously were cumbersome to deal with or were in a chronic, nonhealing state have become manageable. Wounds with exposed bone, tendon, or hardware also have been managed successfully. Numerous adjunctive uses also have been described, showing the versatility and reliability of this method of wound management. The scientific explanations of the benefits of topical negative pressure are ongoing. At the least, multiple elements in the wound-healing process are affected or somehow modified by NPWT. The decision to use any new medical technology must include a cost assessment. NPWT management of a wound incurs some higher costs for the materials that include the sponges, occlusive drapes, and the vacuum machine, which must be rented per diem; however, the duration of dressing changes until final wound healing or definitive wound closure is shorter, compensating for the costs of the materials. Furthermore, as physicians, nurses, and home care specialists become more experienced and adept at managing NPWT, there will be a decrease in the time required. Patients can now be discharged to home while still receiving therapy, thus reducing the need for prolonged inpatient care and these inherent costs. Two recent studies found the cost effectiveness to be comparable to traditional wound therapy with-clinical benefits [54,55].
   NPWT should be considered an important part of the armamentarium for any plastic surgeon dealing with wounds. In the future, there is likely to be a wide range of products and potential indications as this technology continues to evolve.
C1 Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27157 USA.
C3 Wake Forest University
RP Thompson, JT (通讯作者)，Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27157 USA.
EM jimthomp@wfubmc.edu
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 56
TC 65
Z9 74
U1 1
U2 11
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0094-1298
EI 1558-0504
J9 CLIN PLAST SURG
JI Clin. Plast. Surg.
PD OCT
PY 2007
VL 34
IS 4
BP 673
EP +
DI 10.1016/j.cps.2007.07.005
PG 14
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 238US
UT WOS:000251473800007
PM 17967622
DA 2026-07-24
ER

PT J
AU Lin, KC
   Li, YS
   Tarng, YW
AF Lin, Kai Cheng
   Li, Yi-Syuan
   Tarng, Yih-Wen
TI Safety and Efficacy of Prophylactic Closed Incision Negative Pressure
   Therapy after Acute Fracture Surgery
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Article
DE High energy trauma; Orthopeadic trauma; Closed incision; Negative
   pressure wound therapy
ID VACUUM-ASSISTED CLOSURE; WOUND THERAPY; COMPARTMENT SYNDROME; SURGICAL
   INCISIONS; MANAGEMENT
AB Introduction: Soft tissue swelling after acute fracture surgery is a challenge which may increase wound dehiscence, delay early range of motion, and increase infection rate postoperatively. This study investigates closed incision negative pressure therapy (ciNPT) using wide-range cover over the incision site and the peripheral swelling trauma zone to promote early active motion and to mitigate joint stiffness, bulla formation, and tendon adhesion.
   Methods: Twenty-nine patients were enrolled between January 2018 and December 2018. Patients with high-energy soft tissue trauma and comminuted fractures over distal end of limbs (hand and foot; wrist and ankle) or muscle scarcity areas (tibial shaft or patella) were included. ciNPT was applied over closed incisions in the operating room and subatmospheric pressure (-125 mmHg) initiated continuously for 5 similar to 7 days.
   Results: In hand and foot patients (n=8), active motion over all fingers or toes occurred after postoperative Day 2. Mild swelling without any bullous formation was observed over the dorsal aspect of hand. In wrist and ankle patients (n=16), flexion angle over the finger joints over 90 degrees was observed after 5 days post-surgery. For patients with tibial shaft comminuted fractures with impending compartment syndrome, early active motion of knee and ankle joint was observed as soft tissue swelling and distension pain had subsided after surgery.
   Conclusion: The prophylactic ciNPT use in the trauma area after surgery reduced postoperative distension pain and improved early range of motion of the tendon and joint in these patients. (C) 2020 The Author(s). Published by Elsevier Ltd.
C1 [Lin, Kai Cheng; Li, Yi-Syuan; Tarng, Yih-Wen] Kaohsiung Vet Gen Hosp, Dept Orthopaed, 386 Da Chung 1st Rd, Kaohsiung 813, Taiwan.
   [Tarng, Yih-Wen] Natl Def Med Ctr, Dept Orthopaed, 161,Sect 6,Minquan E Rd, Taipei 114, Taiwan.
C3 Kaohsiung Veterans General Hospital; National Defense Medical University
RP Tarng, YW (通讯作者)，Kaohsiung Vet Gen Hosp, Dept Orthopaed, 386 Da Chung 1st Rd, Kaohsiung 813, Taiwan.
EM qm1047@ms35.hinet.net
OI Li, Yi-Syuan/0000-0002-4936-3123
FU KCI
FX KCI provided funding for this study.
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   Fry WR, 2013, EUR J TRAUMA EMERG S, V39, P561, DOI 10.1007/s00068-013-0329-8
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NR 23
TC 4
Z9 5
U1 0
U2 1
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0020-1383
EI 1879-0267
J9 INJURY
JI Injury-Int. J. Care Inj.
PD AUG
PY 2020
VL 51
IS 8
BP 1805
EP 1811
DI 10.1016/j.injury.2020.05.032
PG 7
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA MR8WK
UT WOS:000553870800017
PM 32507454
OA hybrid
DA 2026-07-24
ER

PT J
AU Kleeven, A
   Van der Hel, SRP
   Jonis, YMJ
   Profar, JJA
   Daemen, JHT
   de Loos, ER
   Van der Hulst, RRWJ
   Qiu, SS
AF Kleeven, Alieske
   Van der Hel, Seth Rianna P.
   Jonis, Yasmine M. J.
   Profar, Jairo J. A.
   Daemen, Jean H. T.
   de Loos, Erik R.
   Van der Hulst, Rene R. W. J.
   Qiu, Shan Shan
TI Chest wall reconstruction after the Clagett procedure and other types of
   open-window thoracostomy: a narrative review
SO JOURNAL OF THORACIC DISEASE
LA English
DT Review
DE Empyema; Clagett; open-window thoracostomy; reconstruction
ID PARASPINOUS MUSCLE FLAP; BRONCHOPLEURAL FISTULA; SUCCESSFUL CLOSURE;
   CHRONIC EMPYEMA; MANAGEMENT; CAVITY; SPACE
AB Background and Objective: The Clagett procedure is one of the last treatment options for chronic stage pleural empyema. It involves the formation of an open-window in the thoracic wall to allow for continuous drainage and irrigation of the pleural cavity. Once the empyema has been resolved, reconstruction of the chest wall is sometimes challenging. This review aims to identify and summarize the options for reconstructing soft tissue defects of the chest wall following the Clagett procedure and other types of open window thoracostomy.
   Methods: A narrative review was performed of the literature on PubMed, Cochrane Library, ClinicalTrials.gov, and Google Scholar, including all relevant studies published until January 2023.
   Key Content and Findings: This review contains an overview of the reconstruction methods and the outcomes of the included studies on reconstructive options after the Clagett procedure and other types of open-window thoracostomy. A subdivision was made based on reconstruction type: pedicled flaps, free flaps, and the use of a vacuum-assisted closure (VAC) device. The advantages of pedicled flaps are reliable vascularization, better tissue match, reduced scarring, and shorter operation time compared to free flaps. However, when pedicled flaps are not available due to damage during previous surgeries or offer insufficient volume to obliterate the cavity, free flaps might be a solution.
   Conclusions: In cases where an open-window thoracostomy necessitates chest wall reconstruction, a pedicled flap is the preferred choice, followed by free flaps. Additionally, vacuum-assisted negative pressure wound therapy (VANPWT) techniques have shown potentially promising results (as an adjunct to surgical treatment).
C1 [Kleeven, Alieske; Van der Hel, Seth Rianna P.; Jonis, Yasmine M. J.; Profar, Jairo J. A.; Van der Hulst, Rene R. W. J.; Qiu, Shan Shan] Maastricht Univ, Med Ctr, Dept Plast Reconstruct & Hand Surg, P Debyelaan 25, NL-6229 HX Maastricht, Netherlands.
   [Daemen, Jean H. T.; de Loos, Erik R.] Zuyderland Med Ctr, Div Gen Thorac Surg, Dept Surg, Heerlen, Netherlands.
C3 Maastricht University; Maastricht University Medical Centre (MUMC);
   Zuyderland Medical Center
RP Qiu, SS (通讯作者)，Maastricht Univ, Med Ctr, Dept Plast Reconstruct & Hand Surg, P Debyelaan 25, NL-6229 HX Maastricht, Netherlands.
EM shanshan.qiushao@mumc.nl
OI qiu, shan shan/0000-0002-0616-9566
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NR 44
TC 6
Z9 7
U1 0
U2 1
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2072-1439
EI 2077-6624
J9 J THORAC DIS
JI J. Thorac. Dis.
PD DEC
PY 2023
VL 15
IS 12
BP 7063
EP 7076
DI 10.21037/jtd-23-684
EA DEC 2023
PG 14
WC Respiratory System
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System
GA ED4F6
UT WOS:001117020100001
PM 38249872
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Drossos, G
   Ampatzidou, F
   Baddour, A
   Madesis, A
   Karaiskos, T
AF Drossos, George
   Ampatzidou, Fotini
   Baddour, Antonios
   Madesis, Athanasios
   Karaiskos, Theodoros
TI The impact of deep sternal wound infections treated by negative pressure
   on early, 1 year and late mortality: A longitudinal case-control study
SO JOURNAL OF CARDIAC SURGERY
LA English
DT Article
DE cardiac surgery; deep sternal wound infection; mortality; negative
   pressure
ID VACUUM-ASSISTED CLOSURE; POST-STERNOTOMY MEDIASTINITIS; LONG-TERM
   SURVIVAL; THERAPY; MANAGEMENT; SURGERY
AB Background/Aim Deep sternal wound infection (DSWI) after cardiac surgery, is a rare complication that can be fatal. Due to a lack of available data, we compared early in-hospital, 1-year and long-term mortality in patients with DSWI. Methods Patients undergoing any type of cardiac surgery, in the Cardiothoracic Surgery Department of G. Papanikolaou Hospital, between May 2012 and December 2016, were investigated. All patients who developed DWSI postoperatively, treated with negative pressure wound therapy (NPWT), were included in the group of cases. A random population from the rest of the patients was selected in a 1:2 ratio, representing controls. Results From a total of 2104 patients, 80 patients (3.8%) developed DSWI (cases group), whereas 180 patients were randomly selected as controls. Early (within 30 days) mortality was significantly higher in the DSWI group compared with controls (15% vs 3.9%, respectively; P = .002). Similarly, more deaths occurred in the cases group compared with controls during the follow-up (ie, 19 vs 12, respectively; P < .001); the majority of deaths (84.2%) occurred within the first year. Long-term survival did not differ between the two study groups during follow-up (median duration = 1072 vs 1022 days for cases and controls, respectively). Conclusions DSWI significantly increased early and 1-year mortality in poststernotomy patients treated with NPWT compared with those not developing this complication. However, long-term survival was similar between the two study groups, thus highlighting the beneficial effect of NPWT in terms of clinical outcomes in patients with DWSI.
C1 [Drossos, George; Baddour, Antonios; Madesis, Athanasios; Karaiskos, Theodoros] G Papanikolaou Gen Hosp, Dept Cardiothorac Surg, Thessaloniki, Greece.
   [Ampatzidou, Fotini] G Papanikolaou Gen Hosp, Cardiothorac Intens Care Unit, Thessaloniki 57010, Greece.
C3 George Papanikolaou General Hospital of Thessaloniki; George
   Papanikolaou General Hospital of Thessaloniki
RP Ampatzidou, F (通讯作者)，G Papanikolaou Gen Hosp, Cardiothorac Intens Care Unit, Thessaloniki 57010, Greece.
EM fampatzidou@gmail.com
RI MADESIS, ATHANASIOS/HLW-5269-2023
CR Baillot R, 2010, EUR J CARDIO-THORAC, V37, P880, DOI 10.1016/j.ejcts.2009.09.023
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NR 27
TC 9
Z9 9
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0886-0440
EI 1540-8191
J9 J CARDIAC SURG
JI J. Card. Surg.
PD DEC
PY 2019
VL 34
IS 12
BP 1550
EP 1555
DI 10.1111/jocs.14296
EA OCT 2019
PG 6
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA JU0IZ
UT WOS:000492605800001
PM 31654592
DA 2026-07-24
ER

PT J
AU Zaidi, A
   El-Masry, S
AF Zaidi, A.
   El-Masry, S.
TI Closed-incision negative-pressure therapy in high-risk general surgery
   patients following laparotomy: a retrospective study
SO COLORECTAL DISEASE
LA English
DT Article
DE Closed incision; negative-pressure therapy; general surgery; laparotomy;
   high risk
ID SURGICAL SITE INFECTION; VACUUM-ASSISTED CLOSURE; RANDOMIZED
   CONTROLLED-TRIAL; OPEN COLORECTAL SURGERY; WOUND THERAPY; MANAGEMENT;
   MECHANISMS; RESECTION; PROTOCOL; COST
AB Aim Surgical site infection (SSI) and wound dehiscence are dreaded complications following laparotomy in general surgical patients, and can potentially occur more often in various comorbid states. Negative-pressure wound therapy (NPWT) has a positive effect of on open and complicated wounds and so has been used for atrisk surgical incisions with the aim of redistributing lateral tension and holding incision edges together. The aim of the present study was to compare the rate of wound complications following laparotomy in high-risk general surgical patients with a clean incision treated with closed-incision negative-pressure therapy (ciNPT) with those receiving conventional care.
   Method A retrospective review was performed of the hospital medical records of patients who underwent laparotomy between 1 October 2010 and 31 March 2012. Records of 69 patients who received ciNPT and 112 who were managed by adherent gauze dressings were included in the final analysis.
   Results Two (2.9%) patients in the ciNPT group and 23 (20.5%) in the non-NPWT group developed a wound complication following laparotomy (P < 0.0009). The relative risk (RR) was 0.14 (0.03-0.58), suggesting that infection is less likely to occur in ciNPT-treated incisions, compared with gauze dressings.
   Conclusion ciNPT was associated with a positive clinical outcome and was a safe and effective method of postsurgical management in our general surgery patients considered to have risk of developing wound complications following laparotomy.
C1 [Zaidi, A.] North Tees & Hartlepool NHSFT, Stockton, CA USA.
   [El-Masry, S.] Our Lady Lourdes, Louth, Ireland.
RP El-Masry, S (通讯作者)，Our Lady Lourdes Hosp, Consultant Colorectal Surgeon, FRCSI, Louth, Ireland.
EM selmasry@rcsi.ie
CR Altman D., 1990, PRACTICAL STAT MED R, V1st, P365, DOI [10.1201/9780429258589/practical-statistics-medical-research-douglas-altman, DOI 10.1201/9780429258589/PRACTICAL-STATISTICS-MEDICAL-RESEARCH-DOUGLAS-ALTMAN]
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NR 25
TC 51
Z9 56
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1462-8910
EI 1463-1318
J9 COLORECTAL DIS
JI Colorectal Dis.
PD MAR
PY 2017
VL 19
IS 3
BP 283
EP 287
DI 10.1111/codi.13458
PG 5
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA EP3FD
UT WOS:000397267300010
PM 27416813
OA hybrid
DA 2026-07-24
ER

PT J
AU Tsuji, S
   Ikai, A
   Oyama, K
   Kin, H
   Koizumi, J
AF Tsuji, Shigeto
   Ikai, Akio
   Oyama, Kotaro
   Kin, Hajime
   Koizumi, Junichi
TI Outcomes of primary sternal closure for postoperative mediastinitis in
   children
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article
DE Postoperative mediastinitis; Primary sternal closure; Delayed sternal
   closure; Pectoralis major muscle flaps; Negative pressure wound therapy
ID VACUUM-ASSISTED CLOSURE; MUSCLE FLAP; MANAGEMENT; INFECTION; RUPTURE;
   INFANTS
AB OBJECTIVES: We retrospectively analysed outcomes of debridement and primary sternal closure for postoperative mediastinitis in children.
   METHODS: Between January 2007 and July 2019, 1285 patients under the age of 20years underwent congenital heart surgery at the Iwate Medical University. Of these, 22 children had postoperative mediastinitis (1.7%). We performed adequate debridement and primary sternal closure with pectoralis major muscle advancement flaps. We evaluated hospital survival rates, reintervention, duration of intravenous antibiotic treatment, intensive care unit (ICU) stay and hospital stay.
   RESULTS: The median age and weight at surgery were 12.5months (range 0-228 months) and 7.8 kg (range 2.2-64.2 kg), respectively. Two patients (9%) had a history of delayed sternal closure. Staphylococcus was the most common causative agent for infection (82%). All cases were categorized as Robicsek's classification type II mediastinitis. The hospital survival rate was 95%, and freedom from reintervention for infectious complications was observed in 91% of the patients. The median durations of intravenous antibiotic treatment, ICU stay and hospital stay were 18 days (range 9-46 days), 4 days (range 1-87 days) and 22.5 days (range 11-87 days). The median follow-up time was 89 months (range 2-148 months), and there was no evidence of recurrent mediastinitis, musculoskeletal growth, physical deformity, breast development and upper trunk or limb movement.
   CONCLUSIONS: Primary sternal closure is an effective procedure for children as it can significantly shorten treatment duration and reduce physical and psychological burdens. Its results compare favourably with those of conventional therapy in terms of mortality and complications.
C1 [Tsuji, Shigeto; Kin, Hajime; Koizumi, Junichi] Iwate Med Univ, Dept Cardiovasc Surg, Morioka, Iwate, Japan.
   [Ikai, Akio] Mt Fuji Shizuoka Childrens Hosp, Dept Cardiovasc Surg, Shizuoka, Japan.
   [Oyama, Kotaro] Iwate Med Univ, Dept Pediat, Morioka, Iwate, Japan.
C3 Iwate Medical University; Iwate Medical University
RP Koizumi, J (通讯作者)，Iwate Med Univ, Dept Cardiovasc Surg, 2-1-1 Idaidori, Yahaba, Iwate 0283695, Japan.
EM jkoizumi@iwate-med.ac.jp
RI Tsuji, Shigeto/OGP-9757-2025
OI Koizumi, Junichi/0000-0002-3940-8957
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NR 15
TC 2
Z9 2
U1 0
U2 1
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
EI 1873-734X
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD MAY
PY 2021
VL 59
IS 5
BP 951
EP 957
DI 10.1093/ejcts/ezaa477
EA FEB 2021
PG 7
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA SR9CS
UT WOS:000661342500003
PM 33576375
OA Bronze
DA 2026-07-24
ER

PT J
AU Cristaudo, A
   Jennings, S
   Gunnarsson, R
   Decosta, A
AF Cristaudo, Adam
   Jennings, Scott
   Gunnarsson, Ronny
   Decosta, Alan
TI Complications and Mortality Associated with Temporary Abdominal Closure
   Techniques: A Systematic Review and Meta-Analysis
SO AMERICAN SURGEON
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; TOPICAL NEGATIVE-PRESSURE; DAMAGE-CONTROL
   LAPAROTOMY; OPEN ABDOMEN TREATMENT; PRIMARY FASCIAL CLOSURE; DELAYED
   PRIMARY CLOSURE; SEVERE INTRAABDOMINAL INFECTION; AORTIC-ANEURYSM
   REPAIR; COMPARTMENT SYNDROME; OPEN MANAGEMENT
AB Temporary abdominal closure (TAC) techniques are routinely used in the open abdomen. Ideally, they should prevent evisceration, aid in removal of unwanted fluid from the peritoneal cavity, facilitate in achieving safe definitive fascial closure, as well as prevent the development of intra-abdominal complications. TAC techniques used in the open abdomen were compared with negative pressure wound therapy (NPWT) to identifywhich was superior. Asystematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines involving Medline, Excerpta Medica, Cochrane Central Register of Controlled Trials, Cumulative Index toNursing andAlliedHealth Literature, and Clinicaltrials. gov. All studies describing TAC technique use in the open abdomen were eligible for inclusion. Data were analyzed per TAC technique in the form of a meta-analysis. A total of 225 articles were included in the final analysis. A meta-analysis involving only randomized controlled trials showed that NPWT with continuous fascial closure was superior to NPWT alone for definitive fascial closure [ mean difference (MD): 35% +/- 23%; P = 0.0044]. A subsequent meta-analysis involving all included studies confirmed its superiority across outcomes for definitive fascial closure (MD: 19% +/- 3%; P < 0.0001), perioperative (MD: -4.0% +/- 2.4%; P 5 0.0013) and in-hospital (MD: -5.0% +/- 2.9%; P = 0.0013) mortality, entero-atmospheric fistula (MD: -2.0% +/- 1.8%; P = 0.0041), ventral hernia (MD: -4.0% +/- 2.4%; P = 0.0010), and intra-abdominal abscess (MD: -3.1% 6 2.1%; P = 0.0044). Therefore, it was concluded that NPWTwith continuous fascial traction is superior to NPWTalone.
C1 [Cristaudo, Adam] Univ Sydney, Sydney Med Sch, Camperdown, NSW, Australia.
   [Jennings, Scott] Flinders Med Ctr, Dept Cardiothorac Surg, Adelaide, SA, Australia.
   [Gunnarsson, Ronny] James Cook Univ, Cairns Hosp, Sch Med, Cairns, Qld, Australia.
   [Decosta, Alan] Cairns Hosp, Dept Surg, Cairns, Qld, Australia.
C3 University of Sydney; Flinders Medical Centre; Queensland Health; Cairns
   Hospital; James Cook University; Queensland Health; Cairns Hospital
RP Cristaudo, A (通讯作者)，Univ Sydney, Sydney Med Sch, Camperdown, NSW, Australia.; Cristaudo, A (通讯作者)，2 Hubner Dr, Rothwell, Qld 4022, Australia.
EM adamcristaudo@bigpond.com
RI Gunnarsson, Ronny Kent/AAH-4811-2019; de Costa, Alan/AAZ-3441-2021
OI Gunnarsson, Ronny Kent/0000-0001-9183-3072; de Costa,
   Alan/0000-0001-8116-8099
FU University of Sydney and the academic staff of the Sydney Medical
   School's Discipline of Surgery
FX I would like to acknowledge the support of the University of Sydney and
   the academic staff of the Sydney Medical School's Discipline of Surgery.
   In particular, Dr. Kerry Hitos for the support throughout the surgical
   research component of Masters of Surgery coursework, which you so kindly
   are continuing as I embark on of my PhD. I would also like to
   acknowledge the last minute statistical support from Dr. RobertWare from
   University of Queensland School of Medicine. I would also like to
   especially acknowledge the strong support I have received from my family
   and friends in regard to this research. Especially to my wife, who has
   spent the majority of the last year watching as I stare at my computer.
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NR 250
TC 39
Z9 49
U1 0
U2 14
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0003-1348
EI 1555-9823
J9 AM SURGEON
JI Am. Surg.
PD FEB
PY 2017
VL 83
IS 2
BP 191
EP 216
PG 26
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EO7ZC
UT WOS:000396907600020
PM 28228207
DA 2026-07-24
ER

PT J
AU Zhu, YS
   Lin, YZ
   Xie, SJ
   Yang, MX
   Zhang, W
   Wu, MJ
   Liu, YF
   Xu, DY
   Xian, SY
   Tong, XR
   Huang, J
   Jiang, LF
   Guo, XY
   Gu, MY
   Yu, HK
   Ding, XR
   Li, YX
   Du, YY
   He, H
   Lu, JY
   Huang, RZ
   Ji, SZ
AF Zhu, Yushu
   Lin, Yizhen
   Xie, Sujie
   Yang, Mingxuan
   Zhang, Wei
   Wu, Minjuan
   Liu, Yifan
   Xu, Dayuan
   Xian, Shuyuan
   Tong, Xirui
   Huang, Jie
   Jiang, Luofeng
   Guo, Xinya
   Gu, Minyi
   Yu, Hengkai
   Ding, Xinran
   Li, Yixu
   Du, Yiyao
   He, Heng
   Lu, Jianyu
   Huang, Runzhi
   Ji, Shizhao
TI Mapping intellectual structures and research hotspots of chronic wound
   in global perspective
SO REGENERATIVE THERAPY
LA English
DT Article
DE Chronic wounds; Healing; Management; Negative pressure wound therapy
   (NPWT); Dressings
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT WOUNDS; BED PREPARATION; THERAPY;
   MULTICENTER; ULCERS; MECHANISM; DRESSINGS; DEBRIDEMENT; CHALLENGES
AB Background: Chronic wounds included but were not limited to diabetes foot ulcers, venous leg ulcers and pressure ulcers. The challenge of difficult healing placed a heavy burden on patients and society. Our objective was to explain the healing process of chronic wounds and the development of treatment technologies in the past few years and to provide relevant, valuable information. Methods: Our scientific publications were retrieved from the core collection of the Web of Science (WoSCC) database collection. The bibliometric visualization and analysis were performed by the software Biblioshiny based on R-bibliometrix. VOSviewer software and Citespace software were responsible for the validation of the results. Results: A total of 8129 articles related to wound healing in chronic wounds were retrieved. The countries, institutions, and journals with the highest number of publications were the USA, the N8 research partnership, and the Journal of Wound Care, respectively. Armstrong DG and Dumville JC were the most influential authors in this field. The keyword analysis showed two key clusters of keywords, including "dressings" and "management". Trend topics analysis revealed frequent keywords in recent years, including "nanofibers" and "injectable hydrogels". Conclusion: Our research was the first to reveal the cellular and molecular mechanisms and key clinical management strategies in the healing process of chronic wounds in the future through metrological and systematic evaluation, which may have important translational value in the future. (c) 2025 The Author(s). Published by Elsevier BV on behalf of The Japanese Society for Regenerative Medicine. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/lice nses/by-nc-nd/4.0/).
C1 [Zhu, Yushu; Xie, Sujie; Zhang, Wei; Xu, Dayuan; Xian, Shuyuan; Tong, Xirui; Huang, Jie; Jiang, Luofeng; Guo, Xinya; Gu, Minyi; Yu, Hengkai; Ding, Xinran; Li, Yixu; Du, Yiyao; He, Heng; Lu, Jianyu; Huang, Runzhi; Ji, Shizhao] Naval Med Univ, Affiliated Hosp 1, Dept Burn Surg, Shanghai, Peoples R China.
   [Lin, Yizhen; Yang, Mingxuan] Naval Med Univ, Shanghai 200025, Peoples R China.
   [Wu, Minjuan] Naval Mil Med Univ, Dept Histol & Embryol, Shanghai 200433, Peoples R China.
   [Liu, Yifan] Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Dept Urol, Shanghai 200092, Peoples R China.
   [Zhu, Yushu; Xie, Sujie; Zhang, Wei; Xu, Dayuan; Xian, Shuyuan; Tong, Xirui; Huang, Jie; Jiang, Luofeng; Guo, Xinya; Gu, Minyi; Yu, Hengkai; Ding, Xinran; Li, Yixu; Du, Yiyao; He, Heng; Lu, Jianyu; Huang, Runzhi; Ji, Shizhao] Chinese Acad Med Sci, Res Unit Key Tech Treatment Burns & Combined Burns, Beijing, Peoples R China.
C3 Naval Medical University; Naval Medical University; Naval Medical
   University; Shanghai Jiao Tong University; Chinese Academy of Medical
   Sciences - Peking Union Medical College
RP Lu, JY; Huang, RZ; Ji, SZ (通讯作者)，Naval Med Univ, Affiliated Hosp 1, Dept Burn Surg, Shanghai, Peoples R China.
EM 578198334@qq.com; runzhihuang2022@163.com; shizhaoji2022@163.com
RI jiang, luofeng/GPK-2450-2022; Yifan, Liu/AHD-1515-2022; Huang,
   Runzhi/KLY-6298-2024; Yixu, Li/JZD-7782-2024
FU National Natural Science Foundation of China [81930057, 82472546]; CAMS
   Innovation Fund for Medical Sciences [2019-I2M-5-076]; Shanghai Top
   Priority Research Center Project [2023ZZ02013]; Excellent Academic
   Leader Project of Shanghai Science and Technology Committee [23XD142500
   0]; Deep Blue Talent Project of Naval Medical University; Postdoctoral
   Fellowship Program of CPSF [96926]; Shanghai Rising-Star Program
   (Sailing Special Program) [23YF145840 0]
FX This work was supported by the National Natural Science Foundation of
   China (81930057, 82472546) , CAMS Innovation Fund for Medical Sciences
   (2019-I2M-5-076) , Shanghai Top Priority Research Center Project
   (2023ZZ02013) , the Excellent Academic Leader Project of Shanghai
   Science and Technology Committee (23XD142500 0) , Deep Blue Talent
   Project of Naval Medical University, Postdoctoral Fellowship Program of
   CPSF (96926) and Shanghai Rising-Star Program (Sailing Special Program)
   (No. 23YF145840 0) . The funders had no role in study design, data
   collection and analysis, decision to publish, or preparation of the
   manuscript.
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NR 69
TC 0
Z9 0
U1 2
U2 18
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 2352-3204
J9 REGEN THER
JI Regen. Ther.
PD DEC
PY 2025
VL 30
BP 47
EP 62
DI 10.1016/j.reth.2025.05.002
EA MAY 2025
PG 16
WC Cell & Tissue Engineering; Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Engineering
GA 3DJ7O
UT WOS:001497662200001
PM 40491561
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Aerden, D
   Bosmans, I
   Vanmierlo, B
   Spinnael, J
   Keymeulen, B
   Van den Brande, P
AF Aerden, D.
   Bosmans, I.
   Vanmierlo, B.
   Spinnael, J.
   Keymeulen, B.
   Van den Brande, P.
TI Skin grafting the contaminated wound bed: reassessing the role of the
   preoperative swab
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE wound culture; split thickness skin grafting; negative wound pressure
   therapy; wound bed preparation
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT; SUCCESS; INFECTIONS; DRESSINGS;
   SURFACE
AB Objective: To investigate use of the preoperative wound swab to predict graft failure compared with establishing the indication for skin grafting on clinical grounds alone.
   Method: Patients requiring meshed split-thickness skin grafting were prospectively included; the indication for grafting was established on clinical grounds exclusively. A preoperative swab of the wound bed was taken, but its result was concealed to prevent it influencing clinical decision-making. Negative pressure wound therapy (NPWT) was used for both wound bed preparation and graft fixation. After 2 months, graft area take percentage was measured using digital image processing software and the results validated against the result of the preoperative wound swab.
   Results: Eighty-seven wounds were included in the study. Mean graft area take percentage was 88%, with five grafts considered complete failures (< 25% take). A posteriori analysis of the wound cultures showed that 53% had been contaminated on grafting, but these did not fare any worse than near-sterile wounds. Qualitative analysis of cultures showed that wounds containing either Pseudomonas aeruginosa or Staphylococcus aureus did have inferior outcome (mean take percentage 78.9% vs 91.3%; p=0.038). Diabetes was also a deteriorating factor (mean take percentage 83.0% vs 90.7%; p=0.004).
   Conclusion: Establishing the indication for skin grafting on clinical grounds exclusively does not yield grossly inferior results. In light of recent advances in skin grafting, including use of NPWT as adjuvant therapy, the requirement for routine preoperative wound swabs may be questioned.
   Declaration of interest: There were no external sources of funding for this study. The authors have no conflicts of interest to declare.
C1 [Aerden, D.; Bosmans, I.; Van den Brande, P.] Univ Hosp Brussels, Dept Vasc Surg, Brussels, Belgium.
   [Aerden, D.; Vanmierlo, B.; Keymeulen, B.] Univ Hosp Brussels, Diabet Foot Clin, Brussels, Belgium.
   [Spinnael, J.] Univ Hosp Brussels, Dept Plast Surg, Brussels, Belgium.
   [Spinnael, J.] Univ Hosp Brussels, Wound Care Clin, Brussels, Belgium.
C3 Universite Libre de Bruxelles; University Hospital Brussels; University
   Hospital Brussels; University Hospital Brussels; University Hospital
   Brussels
RP Aerden, D (通讯作者)，Univ Hosp Brussels, Dept Vasc Surg, Brussels, Belgium.
EM isabelle.bosmans@uzbrussel.be
RI ; Aerden, Dimitri/AAM-5294-2021
OI Keymeulen, Bart/0000-0002-8671-4527; Aerden, Dimitri/0000-0001-5384-6147
CR Aerden D, 2011, ANN VASC SURG, V25, P770, DOI 10.1016/j.avsg.2010.12.025
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NR 20
TC 15
Z9 18
U1 0
U2 15
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
J9 J WOUND CARE
JI J. Wound Care
PD FEB
PY 2013
VL 22
IS 2
BP 85
EP 89
DI 10.12968/jowc.2013.22.2.85
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 085CL
UT WOS:000314589200011
PM 23665663
DA 2026-07-24
ER

PT J
AU Patera, M
   Mizera, R
AF Patera, M.
   Mizera, R.
TI Severe Lower Extremity Infections Treated with Hip Disarticulation -
   Case Series
SO ACTA CHIRURGIAE ORTHOPAEDICAE ET TRAUMATOLOGIAE CECHOSLOVACA
LA Czech
DT Article
DE hip disarticulation; infection; necrotizing fasciitis
ID VACUUM-ASSISTED CLOSURE; NECROTIZING FASCIITIS; WOUND CONTROL;
   EXPERIENCE; MORTALITY; AMPUTEES
AB Hip disarticulation is a major ablative procedure with serious risks as well as consequences for the patient, performed rarely for a lower extremity infection. According to literature, the mortality rate in these procedures reaches up to 60%. Unfavourable prognostic factors are emergency surgeries without adequate preparation of the patient and surgeries indicated for an ischemic terrain infection.
   The authors present four cases of hip disarticulation for severe lower extremity infection. In one patient, the procedure was performed urgently for necrotising fasciitis in the lower extremity extending up to the groin area, in the other three patients for non-healing femoral stump infection following the lower extremity amputation for vascular causes, of which two cases got complicated by the presence of TKA. Two of the patients treated surgically for stump infection died two months after the surgery due to respiratory complications. The two surviving patients underwent the last check one year following the surgery, they are both capable of independent locomotion with two underarm crutches and use the prosthesis only rarely. In the discussion, the factors influencing the mortality rate of the procedure, the principles of surgical and antimicrobial therapy, and the use of the negative-pressure wound therapy are analysed. The underlying principles of the care for patients with severe infections of the musculoskeletal system are infection focus debridement with the removal of foreign material, antibiotic (anti-infective) therapy targeted based on the cultivation results, wound management aimed to prevent contamination with nosocomial strains, and multidisciplinary cooperation orthopaedist/surgeon, infectious disease physician, intensive care specialist, nutrition and rehabilitation specialist, nursing and prosthetic care providers.
C1 [Patera, M.; Mizera, R.] Krajska Nemocnice Liberec As, Traumatol Ortopedicke Ctr, Oddeleni Ortopedie, Husova 357-10, Liberec 46063, Czech Republic.
RP Patera, M (通讯作者)，Krajska Nemocnice Liberec As, Traumatol Ortopedicke Ctr, Oddeleni Ortopedie, Husova 357-10, Liberec 46063, Czech Republic.
EM martin.patera@nemlib.cz
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 18
TC 2
Z9 3
U1 0
U2 6
PU GALEN SRO
PI PRAGUE 5
PA NA BELIDLE 34, PRAGUE 5, 150 00, CZECH REPUBLIC
SN 0001-5415
J9 ACTA CHIR ORTHOP TR
JI Acta Chir. Orthop. Traumatol. Cechoslov.
PD OCT
PY 2017
VL 84
IS 5
BP 396
EP 400
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA FL3IS
UT WOS:000414117200012
PM 29351543
DA 2026-07-24
ER

PT J
AU Wang, Z
   Bai, M
   Long, X
   Zeng, A
   Song, KX
   Wang, XJ
AF Wang, Zhi
   Bai, Ming
   Long, Xiao
   Zeng, Ang
   Song, Kexin
   Wang, Xiaojun
TI New protocol to treat Chinese patients with wound-derived acute severe
   illness
SO INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
LA English
DT Article
DE Wound; emergency treatment; critical; salvage treatment mode; NPWT
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT; EXPERIENCE
AB Background and aim: Treatment of severe acute wounds caused by major injury or infection remains challenging. These wounds are often accompanied by comorbidities such as septic shock or multiple organ failure, in which the prognosis is poor. In China, patients with wound-derived acute severe illness are usually treated by conventional salvage approach, in which life support measures are prioritized before vital organ protection and wound repair. To improve patients' prognosis and quality of life after treatment, our institute established a new salvage protocol that simultaneously provided life-support measures and wound care for patients with wound-derived acute severe illness. This study provided a retrospective review on the outcomes of patients treated with the new salvage protocol. Methods: Records from 2011 to 2013 at Peking Union Medical College Hospital in Beijing, China were reviewed to identify patients with wound-derived acute severe illness treated with the new salvage protocol. The protocol included the proactive wound treatment using negative pressure wound therapy (NPWT). During the treatment with NPWT, emergency department and ICU administered adjunctive therapies as needed. Results: Fifty-six patients were treated with the new protocol. All patients had septic shock and 29/56 (51.8%) required mechanical ventilation. Of patients treated according to the new protocol, 21/56 (37.5%) fully recovered and 29/56 (51.8%) improved sufficiently to be transferred to a general ward. Six patients (10.7%) died of causes unlikely related to NPWT. Conclusion: The new salvage protocol implemented in our institute provided wound care proactively and is beneficial to patients with wound-derived acute severe illness.
C1 Chinese Acad Med Sci, Peking Union Med Coll Hosp, Plast & Cosmet Surg Ctr, Beijing, Peoples R China.
   Peking Union Med Coll, Beijing, Peoples R China.
C3 Chinese Academy of Medical Sciences - Peking Union Medical College;
   Peking Union Medical College Hospital; Chinese Academy of Medical
   Sciences - Peking Union Medical College; Peking Union Medical College
RP Wang, XJ (通讯作者)，Beijing Union Med Coll Hosp, Plast & Cosmet Surg Ctr, 1 Shuaifuyuan, Beijing 100730, Peoples R China.
EM pumchwxj@163.com
RI wang, xiaojun/NFT-0476-2025; /AAT-4908-2020
CR Andros G, 2006, OSTOMY WOUND MANAG, P1
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Driver VR, 2010, J VASC SURG, V52, p17S, DOI 10.1016/j.jvs.2010.06.003
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   Gibney RTN, 2014, KIDNEY INT, V85, P1049, DOI 10.1038/ki.2013.392
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NR 13
TC 0
Z9 0
U1 0
U2 2
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1940-5901
J9 INT J CLIN EXP MED
JI Int. J. Clin. Exp. Med.
PY 2017
VL 10
IS 8
BP 12259
EP 12267
PG 9
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA FF1EX
UT WOS:000408643700108
DA 2026-07-24
ER

PT J
AU Kane, BJ
   Younan, G
   Helm, D
   Dastouri, P
   Prentice-Mott, H
   Irimia, D
   Chan, RK
   Toner, M
   Orgill, DP
AF Kane, Bartholomew J.
   Younan, George
   Helm, Douglas
   Dastouri, Pouya
   Prentice-Mott, Harrison
   Irimia, Daniel
   Chan, Rodney K.
   Toner, Mehmet
   Orgill, Dennis P.
TI Controlled induction of distributed microdeformation in wounded tissue
   via a microchamber array dressing
SO JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
LA English
DT Article
DE microfabrication; microfluidic devices; negative pressure wound therapy;
   micromechanical forces; wound healing
ID VACUUM-ASSISTED CLOSURE; EXTRACELLULAR-MATRIX; THERAPY;
   MECHANOTRANSDUCTION; PROLIFERATION; CHALLENGES; TENSEGRITY; MECHANISMS;
   DEVICES
AB Mechanical stimuli are known to play an important role in determining the structure and function of living cells and tissues. Recent studies have highlighted the role of mechanical signals in mammalian dermal wound healing. However, the biological link between mechanical stimulation of wounded tissue and the subsequent cellular response has not been fully determined. The capacity for researchers to study this link is partially limited by the lack of instrumentation capable of applying controlled mechanical stimuli to wounded tissue. The studies outlined here tested the hypothesis that it was possible to control the magnitude of induced wound tissue deformation using a microfabricated dressing composed of an array of open-faced, hexagonally shaped microchambers rendered in a patch of silicone rubber. By connecting the dressing to a single vacuum source, the underlying wounded tissue was drawn up into each of the microchambers, thereby inducing tissue deformation. For these studies, the dressings were applied to full-thickness murine dermal wounds with 200 mmHg vacuum for 12 h. These studies demonstrated that the dressing was capable of inducing wound tissue deformation with values ranging from 11 to 29%. Through statistical analysis, the magnitude of the induced deformation was shown to be a function of both microchamber height and width. These results demonstrated that the dressing was capable of controlling the amount of deformation imparted in the underlying tissue. By allowing the application of mechanical stimulation with varying intensities, such a dressing will enable the performance of sophisticated mechanobiology studies in dermal wound healing. (C) 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 95A: 333-340, 2010.
C1 [Younan, George; Helm, Douglas; Dastouri, Pouya; Chan, Rodney K.; Orgill, Dennis P.] Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, Boston, MA 02115 USA.
   [Kane, Bartholomew J.] Univ Virginia Hlth Syst, Dept Surg, Div Pediat Surg, Charlottesville, VA 22908 USA.
   [Prentice-Mott, Harrison] Massachusetts Gen Hosp, Ctr Engn Med, BioMEMS Resource Ctr, Boston, MA 02114 USA.
   [Irimia, Daniel; Toner, Mehmet] Massachusetts Gen Hosp, Ctr Engn Med & Surg Serv, Boston, MA 02114 USA.
   [Irimia, Daniel; Toner, Mehmet] Harvard Univ, Sch Med, Boston, MA 02114 USA.
C3 Harvard University; Harvard Medical School; Harvard University Medical
   Affiliates; Brigham & Women's Hospital; University of Virginia;
   University of Virginia (UVA) Health System; Harvard University; Harvard
   University Medical Affiliates; Massachusetts General Hospital; Harvard
   University; Harvard University Medical Affiliates; Massachusetts General
   Hospital; Harvard University; Harvard Medical School
RP Orgill, DP (通讯作者)，Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, Boston, MA 02115 USA.
EM dorgill@partners.org
RI Irimia, Daniel/S-5404-2019; Orgill, Dennis/H-7596-2019; Chan,
   Rodney/P-6422-2017
OI Irimia, Daniel/0000-0001-7347-2082; Orgill, Dennis/0000-0002-8279-7310;
   Younan, George/0000-0001-8502-4850
FU National Institutes of Health [UL1RR 025758-01, P41 EB002503]
FX Contract grant sponsor: National Institutes of Health; contract grant
   numbers: UL1RR 025758-01, P41 EB002503
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NR 30
TC 7
Z9 21
U1 0
U2 18
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1549-3296
EI 1552-4965
J9 J BIOMED MATER RES A
JI J. Biomed. Mater. Res. Part A
PD NOV
PY 2010
VL 95A
IS 2
BP 333
EP 340
DI 10.1002/jbm.a.32840
PG 8
WC Engineering, Biomedical; Materials Science, Biomaterials
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Materials Science
GA 660TF
UT WOS:000282666600001
PM 20607869
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Eckstein, FM
   Pinsel, V
   Wurm, MC
   Wilkerling, A
   Dietrich, EM
   Kreissel, S
   von Wilmowsky, C
   Schlittenbauer, T
AF Eckstein, Fabian Matthias
   Pinsel, Valesca
   Wurm, Matthias Christian
   Wilkerling, Andre
   Dietrich, Eva-Maria
   Kreissel, Sebastian
   von Wilmowsky, Cornelius
   Schlittenbauer, Tilo
TI Antiseptic negative pressure instillation therapy for the treatment of
   septic wound healing deficits in oral and maxillofacial surgery
SO JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
LA English
DT Article
DE Negative pressure wound therapy; VAC; Head and neck; Wound healing
   deficits; Osteoradionecrosis of the jaw; Septic diseases of the jaw
ID VACUUM-ASSISTED CLOSURE; OPEN ABDOMEN; MANAGEMENT; HEAD
AB Introduction: Impaired wound healing, chronic wounds and extended soft tissue defects present a crucial problem in reconstructive surgery of the head and neck region, even more after radiation therapy. In such cases the standard is a prolonged open wound treatment. The negative pressure instillation therapy might present an alternative therapy option.
   Material and methods: In this study the effects of negative pressure instillation therapy on the healing of chronic wounds in 15 patients diagnosed with impaired wound healing were investigated. These based upon infected osteoradionecrosis and osteomyelitis of the jaw. The parameters investigated as markers of the therapeutic success were serum inflammatory parameters i.e. white blood cell counts, wound smear results and wound surface reduction.
   Results: The use of negative pressure instillation therapy lead to a reduction of the bacterial load and formation of a stabile granulation tissue in all but one case. The mean inpatient time of the patients was 13.33 +/- 4.62 days. Between 2 and 8 dressing changes were needed to reach clinical sufficient wound healing results. Secondary intention wound healing could be obtained in 14 out of 15 cases. The crucial part for the successful application was a watertight enoral suturing as oro-cutaneous fistulae were present in most cases.
   Conclusion: The negative pressure instillation therapy poses a good treatment for wound healing problems and extended size soft tissue defects, even when oro-cutaneous fistulae were present. Especially in cases that contraindicate micro-vascular reconstruction, negative pressure instillation therapy could be a good alternative. (C) 2018 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
C1 [Eckstein, Fabian Matthias; Pinsel, Valesca; Wurm, Matthias Christian; Wilkerling, Andre; Dietrich, Eva-Maria; Kreissel, Sebastian; von Wilmowsky, Cornelius; Schlittenbauer, Tilo] Friedrich Alexander Univ Erlangen Nurnberg, Dept Oral & Maxillofacial Surg, Univ Hosp Erlangen, Gluckstr 11, D-91054 Erlangen, Germany.
   [Schlittenbauer, Tilo] Klinikum Augsburg Sud, Sect Oral & Maxillofacial Surg, Dept Otorhinolaryngol, D-86156 Augsburg, Germany.
C3 University of Erlangen Nuremberg; Klinikum Augsburg
RP Eckstein, FM (通讯作者)，Friedrich Alexander Univ Erlangen Nurnberg, Dept Oral & Maxillofacial Surg, Univ Hosp Erlangen, Gluckstr 11, D-91054 Erlangen, Germany.
EM Fabian.Eckstein@uk-erlangen.de
CR Acosta S, 2017, BJS-BRIT J SURG, V104, pE75, DOI 10.1002/bjs.10403
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NR 18
TC 11
Z9 13
U1 1
U2 10
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE,
   LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 1010-5182
EI 1878-4119
J9 J CRANIO MAXILL SURG
JI J. Cranio-MaxilloFac. Surg.
PD MAR
PY 2019
VL 47
IS 3
BP 389
EP 393
DI 10.1016/j.jcms.2018.12.006
PG 5
WC Dentistry, Oral Surgery & Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dentistry, Oral Surgery & Medicine; Surgery
GA HM0HK
UT WOS:000459127800003
PM 30638743
DA 2026-07-24
ER

PT J
AU Yin, YC
   Zhang, RP
   Li, SL
   Guo, JL
   Hou, ZY
   Zhang, YZ
AF Yin, Yingchao
   Zhang, Ruipeng
   Li, Shilun
   Guo, Jialiang
   Hou, Zhiyong
   Zhang, Yingze
TI Negative-pressure therapy versus conventional therapy on split-thickness
   skin graft: A systematic review and meta-analysis
SO INTERNATIONAL JOURNAL OF SURGERY
LA English
DT Review
DE Negative-pressure therapy; Conventional therapy; Split-thickness skin;
   Meta-analysis
ID VACUUM-ASSISTED CLOSURE; FLAP DONOR SITE; WOUND THERAPY;
   CONTROLLED-TRIAL; BACTERIAL LOAD; MANAGEMENT
AB Objective: To compare the clinical outcomes of negative-pressure wound therapy (NPWT) versus conventional therapy on split-thickness skin after grafting surgery.
   Design: Meta-analysis.
   Background: Split-thickness skin grafts are widely used in reconstruction of large skin defects. Conventional therapy causes pain during dressing changing. NPWT is an alternative method to cover the wound bed.
   Methods: The Pubmed, Embase, and Cochrane databases were searched for randomized controlled trials (RCTs) or cohort studies for articles published between 1993 and April 2017 comparing NPWT to conventional wound therapy for split-thickness skin grafts. The rate of graft take was the primary outcome of this meta-analysis. Wound infection and reoperation rate of the wound were secondary outcomes. Data analysis was conducted using the Review Manager 5.3 software.
   Results: Five cohort studies and seven RCTs including 653 patients were eligible for inclusion. Patients treated with NPWT had a significantly higher rate of graft take compared to those treated with conventional therapy [MD=7.02, (95% CI 3.74, 10.31)] (P=.00). NPWT was associated with a reduction in reoperation [RR= 0.28, (95% CI 0.14, 0.55)] (P=.00). The reduction in wound infection was not significant [RR=0.63, (95% CI 0.31, 1.27)] (P=.20).
   Conclusion: Compared with conventional therapy, NPWT significantly increases the rate of graft take and reduces the rate of reoperation when applied to cover the wound bed with split-thickness skin graft. No significant impact on wound infection was found in this study.
C1 [Yin, Yingchao; Zhang, Ruipeng; Li, Shilun; Guo, Jialiang; Hou, Zhiyong; Zhang, Yingze] Hebei Med Univ, Hosp 3, Key Lab Biomech Hebei Prov, Dept Orthopaed Surg, 139 Ziqiang Rd, Shijiazhuang 050051, Hebei, Peoples R China.
C3 Hebei Medical University
RP Zhang, YZ (通讯作者)，Hebei Med Univ, Hosp 3, Key Lab Biomech Hebei Prov, Dept Orthopaed Surg, 139 Ziqiang Rd, Shijiazhuang 050051, Hebei, Peoples R China.
EM dryingchao@gmail.com; zhangruipengdoctor@126.com; lshilun@163.com;
   guojialiang11123@163.com; drzyhou@gmail.com; dr_yzzhang@126.com
OI Hou, Zhiyong/0000-0001-5838-4025; Zhang, Ruipeng/0000-0002-1702-8988;
   Yin, Yingchao/0000-0002-0989-9556
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NR 25
TC 84
Z9 101
U1 1
U2 23
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1743-9191
EI 1743-9159
J9 INT J SURG
JI Int. J. Surg.
PD FEB
PY 2018
VL 50
BP 43
EP 48
DI 10.1016/j.ijsu.2017.12.020
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FX2MW
UT WOS:000425895900008
PM 29292216
DA 2026-07-24
ER

PT J
AU Muñoz, V
   Martinez, C
   Echevarria, B
   Fernández, MI
   Pino, A
   Anitua, E
AF Munoz, Victoria
   Martinez, Carmen
   Echevarria, Begona
   Isabel Fernandez, Ma
   Pino, Ander
   Anitua, Eduardo
TI Biological Approach for Managing Severe Gunshot Wounds A Case
   Report
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Gunshot injury; Platelet-rich plasma; Platelet-derived growth factor;
   Skin regeneration; Wound healing
ID PLATELET-RICH PLASMA; GROWTH-FACTORS; AUTOLOGOUS PLATELET; SKIN WOUNDS;
   PRESSURE ULCERS; HYALURONIC-ACID; PRGF-ENDORET; GEL; EFFICACY;
   KERATINOCYTES
AB BACKGROUND: Autologous formulations rich in bioactive proteins promote cutaneous tissue regeneration. This case report describes our experiences with a platelet-based autologous formulation in the management of a hard-to-heal and severe gunshot wound.
   CASE: A healthy, 34-year-old man suffered an accidental gunshot wound of his right foot. After cleansing with saline and application of vacuum-assisted closure therapy for a period of 5 weeks, the resulting full-thickness wound had a surface area of 20 cm(2) and did not show progress toward closure despite ongoing treatment. Plasma-rich growth factor (PRGF) therapy was used in order to promote tissue regeneration. The patient's own blood was drawn, centrifuged, and platelet-rich plasma was obtained. Intradermal injections of freshly activated platelet-rich plasma were administered into the wound edges, and a fibrin membrane was applied on the wound bed. Afterward, a novel topical ointment based on the patient's own growth factors was used as a daily therapy over the affected tissue.
   RESULTS: This full-thickness wound healed after 16 weeks of autologous growth factor therapy. The patient was able to walk without pain.
   CONCLUSION: Plasma-rich growth factor therapy successfully healed this full-thickness wound that did not respond to a period of 5 weeks with negative pressure wound therapy using a vacuum-assisted device. Healing occurred after 16 weeks of treatment, and he was able to resume walking without pain or functional deficits.
C1 [Munoz, Victoria; Martinez, Carmen; Echevarria, Begona; Isabel Fernandez, Ma] Quironsalud Hosp Bizkaia, Erandio, Spain.
   [Pino, Ander; Anitua, Eduardo] BTI Biotechnol Inst, Vitoria, Spain.
   [Anitua, Eduardo] Eduardo Anitua Fdn, Jacinto Quincoces 39, Vitoria, Spain.
C3 quironsalud Group
RP Anitua, E (通讯作者)，Eduardo Anitua Fdn, Jacinto Quincoces 39, Vitoria, Spain.
EM eduardoanitua@eduardoanitua.com
RI Anitua, Eduardo/O-1154-2018
OI Anitua, Eduardo/0000-0002-8386-5303
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NR 46
TC 5
Z9 7
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JUL-AUG
PY 2018
VL 45
IS 4
BP 359
EP 363
DI 10.1097/WON.0000000000000451
PG 5
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA GR6GX
UT WOS:000442746300012
PM 29994865
DA 2026-07-24
ER

PT J
AU Rayman, G
   Vas, P
   Dhatariya, K
   Driver, V
   Hartemann, A
   Londahl, M
   Piaggesi, A
   Apelqvist, J
   Attinger, C
   Game, F
AF Rayman, Gerry
   Vas, Prashanth
   Dhatariya, Ketan
   Driver, Vickie
   Hartemann, Agnes
   Londahl, Magnus
   Piaggesi, Alberto
   Apelqvist, Jan
   Attinger, Chris
   Game, Fran
CA Int Working Grp Diab Foot
TI Guidelines on use of interventions to enhance healing of chronic foot
   ulcers in diabetes (IWGDF 2019 update)
SO DIABETES-METABOLISM RESEARCH AND REVIEWS
LA English
DT Article
DE diabetic foot; dressing; foot ulcer; guidelines; wound healing
ID PRESSURE WOUND THERAPY; HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED
   CLOSURE; AMNIOTIC MEMBRANE ALLOGRAFT; CONTROLLED CLINICAL-TRIAL;
   LOWER-EXTREMITY ULCERS; PLATELET-RICH PLASMA; LEVEL LASER THERAPY;
   DOUBLE-BLIND; GROWTH-FACTOR
AB The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and expert consultants in the field, this update is based on a systematic review of the literature centred on the following: the Population (P), Intervention (I), Comparator (C) and Outcomes (O) framework; the use of the SIGN guideline/Cochrane review system; and the 21 point scoring system advocated by IWGDF/EWMA. This has resulted in 13 recommendations. The recommendation on sharp debridement and the selection of dressings remain unchanged from the last recommendations published in 2016. The recommendation to consider negative pressure wound therapy in post-surgical wounds and the judicious use of hyperbaric oxygen therapy in certain non-healing ischaemic ulcers also remains unchanged. Recommendations against the use of growth factors, autologous platelet gels, bioengineered skin products, ozone, topical carbon dioxide, nitric oxide or interventions reporting improvement of ulcer healing through an alteration of the physical environment or through other systemic medical or nutritional means also remain. New recommendations include consideration of the use of sucrose-octasulfate impregnated dressings in difficult to heal neuro-ischaemic ulcers and consideration of the use of autologous combined leucocyte, platelet and fibrin patch in ulcers that are difficult to heal, in both cases when used in addition to best standard of care. A further new recommendation is the consideration of topical placental derived products when used in addition to best standard of care.
C1 [Rayman, Gerry] East Suffolk & North East Essex Fdn Trust, Diabet Ctr, Colchester, Essex, England.
   [Rayman, Gerry] East Suffolk & North East Essex Fdn Trust, Res Unit, Colchester, Essex, England.
   [Vas, Prashanth] Kings Coll Hosp London, Diabet Foot Clin, London, England.
   [Dhatariya, Ketan] Norfolk & Norwich Univ Hosp NHS Fdn Trust, Dept Diabet, Norwich, Norfolk, England.
   [Dhatariya, Ketan] Univ East Anglia, Norwich, Norfolk, England.
   [Driver, Vickie] Brown Univ, Sch Med, Providence, RI 02912 USA.
   [Hartemann, Agnes] Paris 6 Univ, ICAN, Pitie Salpetriere Hosp, APHP, Paris, France.
   [Londahl, Magnus] Skane Univ Hosp, Dept Endocrinol, Lund, Sweden.
   [Londahl, Magnus] Lund Univ, Dept Clin Sci, Lund, Sweden.
   [Piaggesi, Alberto] Univ Pisa, Diabet Foot Sect, Dept Med, Pisa, Italy.
   [Apelqvist, Jan] Malmo Univ Hosp, Dept Endocrinol, Malmo, Sweden.
   [Attinger, Chris] Medstar Georgetown Univ Hosp, Dept Plast Surg, Washington, DC USA.
   [Game, Fran] Univ Hosp Derby & Burton NHS Fdn, Dept Diabet & Endocrinol, Derby, England.
C3 King's College Hospital NHS Foundation Trust; King's College Hospital;
   Norfolk & Norwich University Hospitals NHS Foundation Trust; University
   of East Anglia; Brown University; Assistance Publique Hopitaux Paris
   (APHP); Universite Paris Cite; Hopital Universitaire Hotel-Dieu - APHP;
   Hopital Universitaire Pitie-Salpetriere - APHP; Sorbonne Universite;
   Institut National de la Sante et de la Recherche Medicale (Inserm); Lund
   University; Skane University Hospital; Lund University; University of
   Pisa; Lund University; Skane University Hospital; Georgetown University
RP Rayman, G (通讯作者)，East Suffolk & North Essex NHS Fdn, Ipswich Diabet Ctr, TrustHeath Rd, Colchester IP4 5PD, Essex, England.
EM Gerry.Rayman@esneft.nhs.uk
RI ; Rayman, Gerry/KLZ-2200-2024
OI Game, Frances/0000-0002-5294-4789; Vas, Prashanth/0000-0001-7448-2995;
   Löndahl, Magnus/0000-0003-1522-3920
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NR 121
TC 152
Z9 189
U1 2
U2 64
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1520-7552
EI 1520-7560
J9 DIABETES-METAB RES
JI Diabetes-Metab. Res. Rev.
PD MAR
PY 2020
VL 36
SU 1
DI 10.1002/dmrr.3283
PG 14
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA MZ6RW
UT WOS:000559257300035
PM 32176450
OA Bronze
DA 2026-07-24
ER

PT J
AU Bondokji, S
   Rangaswamy, M
   Reuter, C
   Farajalla, Y
   Mole, T
   Cockwill, J
   Smith, J
AF Bondokji, S.
   Rangaswamy, M.
   Reuter, C.
   Farajalla, Y.
   Mole, T.
   Cockwill, J.
   Smith, J.
TI Clinical efficacy of a new variant of a foam-based NWPT system
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE negative pressure wound therapy; polyurethane foam; wound dimensions;
   granulation tissue
ID VACUUM-ASSISTED CLOSURE; PRESSURE-WOUND-THERAPY; RANDOMIZED
   CONTROLLED-TRIAL; MULTICENTER; ULCERS; GAUZE
AB Objective: To evaluate the clinical efficacy of a new variant of a foam-based negative wound pressure wound therapy (NPWT) system.
   Method:A newly available polyurethane foam-based NPWT system (RENASYS-F, Smith & Nephew) was used to treat 18 patients in a prospective, multi-centre study.The patients had a variety of wound types including pressure ulcers, diabetic foot ulcers, traumatic and surgical wounds.
   Results: The mean patient age was 48.3 years (range 25-72). Mean treatment duration was 14.6 days (range 5-29).At the end of therapy, 83% (15) wounds had progressed sufficiently, leading to a change in treatment from NPWT. Median reductions in wound area, depth and volume of 31.3%, 45.5% and 74.2% respectively were observed over the course of therapy.This equated to a weekly reduction in area, depth and volume of 12.9%, 20.0% and 32.1% respectively. Exudate level (p=0.013) and wound malodour (p=0.03) were significantly reduced between the onset and the end of NPWT.The percentage cover of 'beefy' red granulation tissue in the wound bed was significantly increased (p<0.001) and non-viable tissue significantly reduced (p=0.008) between the onset and the end of NPWT.
   Conclusion: These data demonstrate that an alternative foam-based NPWT system (RENASYS-F) is able to address the common treatment goals associated with application of NPWT including reduction in wound dimensions, reduction in exudate levels and an improvement in wound bed quality.
C1 [Bondokji, S.] Int Med Ctr, Jeddah, Saudi Arabia.
   [Rangaswamy, M.] Welcare Hosp, Dubai, U Arab Emirates.
   [Reuter, C.] Al Mafraq Hosp, Abu Dhabi, U Arab Emirates.
   [Farajalla, Y.] Dubai Hosp, Dubai, U Arab Emirates.
   [Mole, T.; Cockwill, J.; Smith, J.] Smith & Nephew, Adv Wound Devices, Kingston Upon Hull, N Humberside, England.
C3 Dubai Hospital; Smith & Nephew
RP Bondokji, S (通讯作者)，Int Med Ctr, Jeddah, Saudi Arabia.
EM Jennifer.Smith@smith-nephew.com
FU Smith Nephew
FX Funding for this study was provided by Smith & Nephew. Authors TM, JC
   and JS are all employees of Smith & Nephew.
CR Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
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NR 15
TC 9
Z9 10
U1 0
U2 11
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD FEB
PY 2011
VL 20
IS 2
BP 62
EP +
DI 10.12968/jowc.2011.20.2.72
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 929YV
UT WOS:000303102700004
PM 21378681
DA 2026-07-24
ER

PT J
AU Dingemans, SA
   Birnie, MFN
   Backes, M
   de Jong, VM
   Luitse, JS
   Goslings, JC
   Schepers, T
AF Dingemans, Siem A.
   Birnie, Merel F. N.
   Backes, Manouk
   de Jong, Vincent M.
   Luitse, Jan S.
   Goslings, J. Carel
   Schepers, Tim
TI Prophylactic negative pressure wound therapy after lower extremity
   fracture surgery: a pilot study (vol 42, pg 747, 2018)
SO INTERNATIONAL ORTHOPAEDICS
LA English
DT Correction
AB The published online version contain mistake in the author list for the name of the author "J. Carel Goslings" was incorrectly presented in the HTML version.
C1 [Dingemans, Siem A.; Birnie, Merel F. N.; Backes, Manouk; de Jong, Vincent M.; Luitse, Jan S.; Goslings, J. Carel; Schepers, Tim] Acad Med Ctr, Dept Surg, Trauma Unit, Meibergdreef 9,POB 22660, NL-1100 DD Amsterdam, Netherlands.
C3 University of Amsterdam; Academic Medical Center Amsterdam
RP Schepers, T (通讯作者)，Acad Med Ctr, Dept Surg, Trauma Unit, Meibergdreef 9,POB 22660, NL-1100 DD Amsterdam, Netherlands.
EM t.schepers@amc.nl
OI Schepers, Tim/0000-0003-1172-4939
CR Dingemans SA, 2018, INT ORTHOP, V42, P747, DOI 10.1007/s00264-018-3781-6
NR 1
TC 0
Z9 0
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0341-2695
EI 1432-5195
J9 INT ORTHOP
JI Int. Orthop.
PD SEP
PY 2018
VL 42
IS 9
BP 2287
EP 2287
DI 10.1007/s00264-018-4055-z
PG 1
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA GR4OY
UT WOS:000442594600034
PM 30014211
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Achiti, A
   Zenati, N
   Seinturier, C
   Cracowski, JL
   Blaise, S
AF Achiti, Alexandru
   Zenati, Nora
   Seinturier, Christophe
   Cracowski, Jean-Luc
   Blaise, Sophie
TI Negative pressure wound therapy with instillation and dwell time in
   debridement of fibrinous leg ulcers
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE chronic; debridement; hard-to-heal; negative pressure wound therapy;
   negative pressure wound therapy with instillation and dwell time; NPWT;
   NPWTi-d; wound; wound care; wound dressing; wound healing
AB Objective: In conjunction with appropriate wound care, negative pressure wound therapy with instillation and dwell time (NPWTi-d) may be used as an adjunct therapy for acute or hard -to -heal (chronic) wounds, especially when infected. However, there are very few data on the use of NPWTi-d in the treatment of fibrinous wounds that are difficult to debride mechanically. The main objective of this study was to describe changes in the fibrin area of such wounds, before and after treatment with NPWTi-d. Method: This was a monocentric, observational, prospective pilot study evaluating the NPWTi-d medical device. Eligible patients included in the study were those with hard -to -heal lower limb ulcers who had previously undergone unsuccessful specific debridement treatment for their wound, with failure of manual mechanic debridement for at least six weeks' duration, and whose wounds had a fibrinous surface area of >70% of the total wound surface area. The primary endpoint was the difference in the percentage of fibrinous surface area before and after treatment. Results: A total of 14 patients who received treatment for lower limb ulcers between October 2017 and August 2019 were included in the study. There was a significant shrinkage rate of the fibrinous wound surface between the start and end of treatment (83.6 +/- 14.5% and 32.2 +/- 19.7%, respectively; p<0.001). Conclusion: This study showed a significant decrease in fibrin area in wounds treated with NPWTi-d, with good tolerance. We believe that NPWTi-d has its place in the multidisciplinary management of patients with hard -to -heal ulcers. Additional randomised studies are required to confirm these findings. Declaration of interest: The authors have no conflicts of interest.
C1 [Achiti, Alexandru; Zenati, Nora; Blaise, Sophie] Ctr Hosp & Univ Grenoble Alpes, Serv Med Vasc, F-38000 Grenoble, France.
   [Seinturier, Christophe; Cracowski, Jean-Luc; Blaise, Sophie] Univ Grenoble Alpes, Inserm, HP2, F-38000 Grenoble, France.
C3 Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA);
   CHU Grenoble Alpes; Institut National de la Sante et de la Recherche
   Medicale (Inserm); Communaute Universite Grenoble Alpes; Universite
   Grenoble Alpes (UGA)
RP Blaise, S (通讯作者)，Ctr Hosp & Univ Grenoble Alpes, Serv Med Vasc, F-38000 Grenoble, France.; Blaise, S (通讯作者)，Univ Grenoble Alpes, Inserm, HP2, F-38000 Grenoble, France.
EM SBlaise@chu-grenoble.fr
RI Cracowski, Jean-Luc/M-6946-2014; Blaise, Sophie/AAS-2389-2020
OI Cracowski, Jean-Luc/0000-0003-0787-1469; 
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   Kim PJ, 2013, PLAST RECONSTR SURG, V132, P1569, DOI 10.1097/PRS.0b013e3182a80586
   Lehner B, 2011, INT ORTHOP, V35, P1415, DOI 10.1007/s00264-011-1274-y
   Lévy E, 2001, J MAL VASCUL, V26, P39
   Livingstone JP, 2018, CUREUS J MED SCIENCE, V10, DOI 10.7759/cureus.3483
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Saeg F, 2021, PLAST RECONSTR SURG, V148, p601E, DOI 10.1097/PRS.0000000000008331
   Saeg F, 2021, PLAST RECONSTR SURG, V148, P226, DOI 10.1097/PRS.0000000000008061
   Uoya Yuichiro, 2019, Wounds, V31, pE61
   Yang CK, 2015, J VASC SURG, V61, P995, DOI 10.1016/j.jvs.2014.11.076
NR 16
TC 4
Z9 5
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD MAR
PY 2024
VL 33
IS 3
BP 166
EP 170
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA QU9D3
UT WOS:001223490900003
PM 38451785
DA 2026-07-24
ER

PT J
AU Fields, AC
   Pradarelli, JC
   Itani, KMF
AF Fields, Adam C.
   Pradarelli, Jason C.
   Itani, Kamal M. F.
TI Preventing Surgical Site Infections Looking Beyond the Current
   Guidelines
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Editorial Material
AB This JAMA Insights Clinical Update summarizes current guidelines for prevention of surgical site infections and discusses emerging prevention strategies, such as preoperative bowel preparation and negative-pressure wound therapy, that are challenging longstanding surgical practices.
C1 [Fields, Adam C.; Pradarelli, Jason C.; Itani, Kamal M. F.] Vet Affairs Boston Healthcare Syst, Dept Surg, Boston, MA USA.
   [Fields, Adam C.; Pradarelli, Jason C.; Itani, Kamal M. F.] Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Boston, MA 02115 USA.
   [Itani, Kamal M. F.] Boston Univ, Sch Med, Dept Surg, Boston, MA 02118 USA.
C3 Harvard University; Harvard University Medical Affiliates; US Department
   of Veterans Affairs; Veterans Health Administration (VHA); VA Boston
   Healthcare System; Harvard University; Harvard Medical School; Harvard
   University Medical Affiliates; Brigham & Women's Hospital; Boston
   University
RP Itani, KMF (通讯作者)，Vet Affairs Boston Healthcare Syst, Dept Surg, 1400 VFW Pkwy,112-C,West, Roxbury, MA 02132 USA.
EM kamal.itani@va.gov
CR Ban KA, 2017, J AM COLL SURGEONS, V224, P59, DOI 10.1016/j.jamcollsurg.2016.10.029
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Branch-Elliman W, 2019, JAMA SURG, V154, P590, DOI 10.1001/jamasurg.2019.0569
   Fry DE, 2020, JAMA SURG, V155, P80, DOI 10.1001/jamasurg.2019.4551
   Grant MC, 2017, ANN SURG, V265, P68, DOI [10.1097/sla.0000000000001703, 10.1097/SLA.0000000000001703]
   Memtsoudis SG, 2019, JAMA-J AM MED ASSOC, V321, P1049, DOI 10.1001/jama.2019.1070
   Rollins KE, 2019, ANN SURG, V270, P43, DOI 10.1097/SLA.0000000000003145
   Sahebally SM, 2018, JAMA SURG, V153, DOI 10.1001/jamasurg.2018.3467
   World Health Organization, 2018, Global guidelines for the prevention of surgical site infection, V2nd
NR 9
TC 48
Z9 56
U1 1
U2 8
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD MAR 17
PY 2020
VL 323
IS 11
BP 1087
EP 1088
DI 10.1001/jama.2019.20830
PG 2
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA KX6DC
UT WOS:000521968800022
PM 32083641
DA 2026-07-24
ER

PT J
AU AbdelDayem, AM
   Nashed, GA
   Balamoun, HA
   Mostafa, MS
AF AbdelDayem, Albraa Mohamed
   Nashed, George Abdelfady
   Balamoun, Hany Armia
   Mostafa, Mohamed Saber
TI Effectiveness of 3-Day Prophylactic Negative Pressure Wound Therapy on
   Closed Abdominal Incisions in the Prevention of Wound Complications: A
   Randomized Controlled Trial
SO JOURNAL OF GASTROINTESTINAL SURGERY
LA English
DT Article
DE Surgical site infection; Prophylactic negative pressure wound therapy;
   Seroma; Hematoma; Delayed healing; Wound dehiscence
ID SURGICAL SITE INFECTION; HIGH-RISK PATIENTS; LAPAROTOMY; SURGERY;
   PHASE-3; IMPACT
AB ObjectiveTo determine the impact of negative pressure wound therapy of closed abdominal incisions on wound complications.BackgroundSurgical wound complications including surgical site infection complicating open abdominal operations are a burden on the economy. The outcomes of SSI include prolonged hospital stays, adjuvant treatment delay, and incisional hernias leading to a decrease in the quality of life. Prophylactic negative pressure wound therapy has recently been tried with promising results.MethodsA randomized controlled trial involving 140 patients post-laparotomy with primary wound closure was divided into 2 groups (70 patients each). For the first group, NPWT dressings were applied for the first 3 days and then conventional dressings for 4 days after. For the second group, conventional dressings were applied for 7 days. Patients were followed up for SSI, seroma, wound dehiscence, and hospital stay.ResultspNPWT was associated with a significantly lower rate of SSI development compared with gauze dressings (3/70 vs. 17/70) (p = 0.001). It also had a significant effect on lowering the incidence of seroma (0/70 vs. 7/70) (p = 0.007) and delayed wound healing (0/70 vs. 8/70) (p = 0.006) and on decreasing days of hospital stay (2.2 & PLUSMN; 0.6 vs. 3.5 & PLUSMN; 1.8) (p <0.00001). No significant difference was observed with regard to hematoma (0/70 vs. 1/70) (p = 0.5) or wound dehiscence (0/70 vs. 2/70) (p = 0.5). No burst abdomens or NPWT complications were recorded in our study.ConclusionThree-day NPWT applied to primarily closed incisions is effective in reducing the incidence of SSI, seroma, and delayed wound healing in abdominal operations compared to conventional gauze dressings.
C1 [AbdelDayem, Albraa Mohamed; Nashed, George Abdelfady; Balamoun, Hany Armia; Mostafa, Mohamed Saber] Cairo Univ, Fac Med, Dept Gen Surg, Cairo, Egypt.
C3 Egyptian Knowledge Bank (EKB); Cairo University
RP AbdelDayem, AM (通讯作者)，Cairo Univ, Fac Med, Dept Gen Surg, Cairo, Egypt.
EM a.m.dayem93@gmail.com; george.ayad@kasralainy.edu.eg;
   hanyarmiabalamoun@kasralainy.edu.eg; d.mohamedsaber@yahoo.com
RI ; AbdelDayem, Albraa/HKO-3923-2023
OI AbdelDayem, Albraa/0000-0001-7370-6336; Mostafa Saber,
   Mohamed/0000-0003-0485-3900; 
CR Andrianello S, 2021, SURGERY, V169, P1069, DOI 10.1016/j.surg.2020.10.029
   Anthony T, 2011, ARCH SURG-CHICAGO, V146, P263, DOI 10.1001/archsurg.2010.249
   Bath M F, 2022, Ann R Coll Surg Engl, V104, P571, DOI [10.1308/rcsann.2022.0075, 10.1308/rcsann.2022.0075]
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Blackham AU, 2013, AM J SURG, V205, P647, DOI 10.1016/j.amjsurg.2012.06.007
   Boland PA, 2021, IRISH J MED SCI, V190, P261, DOI 10.1007/s11845-020-02283-7
   Borejsza-Wysocki M, 2021, VIDEOSURGERY MINIINV, V16, P686, DOI 10.5114/wiitm.2021.106426
   Brennfleck FW, 2020, TRIALS, V21, DOI 10.1186/s13063-020-04831-z
   Flynn J, 2020, SURG INFECT, V21, P231, DOI 10.1089/sur.2019.078
   Galal I, 2011, AM J SURG, V202, P133, DOI 10.1016/j.amjsurg.2010.06.011
   Gheorghe A, 2015, VALUE HEALTH, V18, P1126, DOI 10.1016/j.jval.2015.08.004
   Gok Mehmet Ali, 2019, J Med Life, V12, P276, DOI [10.25122/jml-2019-0033, 10.25122/jml-2019-0033]
   Javed AA, 2019, ANN SURG, V269, P1034, DOI 10.1097/SLA.0000000000003056
   Kuncewitch MP, 2019, AM SURGEON, V85, P1
   Lakhani A, 2022, SURGERY, V172, P949, DOI 10.1016/j.surg.2022.05.020
   Leitao MM Jr, 2020, GYNECOL ONCOL, V159, P53, DOI 10.1016/j.ygyno.2020.06.111
   Li PY, 2017, SCAND J SURG, V106, P189, DOI 10.1177/1457496916668681
   Lozano-Balderas G, 2017, AM SURGEON, V83, P512
   Martin RCG, 2019, HPB, V21, pS26, DOI DOI 10.1016/J.HPB.2019.03.041
   Meyer J, 2020, CLIN INFECT DIS, V73, P3804
   Murphy PB, 2019, ANN SURG, V270, P38, DOI 10.1097/SLA.0000000000003111
   Murray BW, 2011, AM J SURG, V202, P558, DOI 10.1016/j.amjsurg.2011.06.014
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Wick EC, 2009, DIS COLON RECTUM, V52, P374, DOI 10.1007/DCR.0b013e31819a5e45
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   Zaidi A, 2017, COLORECTAL DIS, V19, P283, DOI 10.1111/codi.13458
NR 28
TC 5
Z9 6
U1 0
U2 8
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1091-255X
EI 1873-4626
J9 J GASTROINTEST SURG
JI J. Gastrointest. Surg.
PD AUG
PY 2023
VL 27
IS 8
BP 1702
EP 1709
DI 10.1007/s11605-023-05752-3
EA JAN 2024
PG 8
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA O3YU9
UT WOS:001023694800007
PM 37407900
OA hybrid
DA 2026-07-24
ER

PT J
AU Dingemans, SA
   Birnie, MFN
   Backes, M
   de Jong, VM
   Luitse, JS
   Goslings, JC
   Schepers, T
AF Dingemans, Siem A.
   Birnie, Merel F. N.
   Backes, Manouk
   de Jong, Vincent M.
   Luitse, Jan S.
   Goslings, J. Carel
   Schepers, Tim
TI Prophylactic negative pressure wound therapy after lower extremity
   fracture surgery: a pilot study
SO INTERNATIONAL ORTHOPAEDICS
LA English
DT Article
DE Negative pressure wound therapy; Postoperative wound infection; Lower
   extremity fracture surgery; Prophylactic; Closed incision
ID SURGICAL INCISIONS; TRAUMA; INFECTIONS; TRIAL
AB Purpose Infectious complications following lower extremity fracture surgery are a major concern and account for a substantial socio-economic burden to society. The aim of this pilot study was to investigate the feasibility of a new portable single-use negative pressure wound therapy device in patients undergoing major foot ankle surgery.
   Methods Patients undergoing major foot ankle fracture surgery at a single level 1 trauma centre were eligible for this prospective case series. Patient characteristics were collected, as were fracture and surgical characteristics. Primary outcome was surgical site infection within 30 days as classified by the criteria from the Centers for Disease Control and Prevention. Patients in the prospective cohort were case-matched with a historical cohort from the same institution.
   Results Sixty patients were included. In seven patients, the NPWT failed and treatment was ceased. Mean age was 44 years and 85% was ASA 1; 43% of the patients were actively smoking. Indications for surgery were midfoot, calcaneal, talar, and ankle fractures. In 53 patients, four (7.5%) surgical site infections occurred, two superficial (3.3%) and two (3.3%) deep infections. For 47 patients, a match was available. The incidence of surgical site infection did not statistically significantly differ between the prospective cohort and retrospective matched cohort (4.3 versus 14.9%, p = 0.29, respectively). This was also the case when looking at superficial and deep surgical site infections separately (0 versus 8.5%, p = 0.08, and 4.3 versus 6.4%, respectively).
   Conclusion We have observed surgical site infections in 7.5% of the patients with the use of prophylactic negative pressure wound therapy. The incidence of surgical site infections was not statistically significantly lower compared to a matched historical cohort.
C1 [Dingemans, Siem A.; Birnie, Merel F. N.; Backes, Manouk; de Jong, Vincent M.; Luitse, Jan S.; Goslings, J. Carel; Schepers, Tim] Acad Med Ctr, Trauma Unit, Dept Surg, Meibergdreef 9,POB 22660, NL-1100 DD Amsterdam, Netherlands.
C3 University of Amsterdam; Academic Medical Center Amsterdam
RP Schepers, T (通讯作者)，Acad Med Ctr, Trauma Unit, Dept Surg, Meibergdreef 9,POB 22660, NL-1100 DD Amsterdam, Netherlands.
EM t.schepers@amc.nl
OI Schepers, Tim/0000-0003-1172-4939
FU Smith Nephew ltd [IIS 377]
FX This study was funded by a grant (IIS 377) from Smith & Nephew ltd.
CR Backes M, 2015, ARCH ORTHOP TRAUM SU, V135, P1045, DOI 10.1007/s00402-015-2219-5
   Berrios-Torres SI, 2017, JAMA SURG, P1
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   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   Dingemans SA, 2016, J ORTHOP TRAUMA
   Gans I, 2017, PATIENT SAF SURG, V11, DOI 10.1186/s13037-016-0118-5
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   Whitehouse JD, 2002, INFECT CONT HOSP EP, V23, P183, DOI 10.1086/502033
NR 20
TC 20
Z9 20
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0341-2695
EI 1432-5195
J9 INT ORTHOP
JI Int. Orthop.
PD APR
PY 2018
VL 42
IS 4
BP 747
EP 753
DI 10.1007/s00264-018-3781-6
PG 7
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA GA8PT
UT WOS:000428602900003
PM 29376199
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Cole, W
AF Cole, Windy
TI Early-stage Management of Complex Lower Extremity Wounds Using Negative
   Pressure Wound Therapy With Instillation and a Reticulated Open Cell
   Foam With Through Holes
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE lower extremity wounds; negative pressure wound therapy with
   instillation and dwell time; NPWTi-d; wound complications; debridement;
   wound cleansing
ID OUTCOMES
AB Introduction. Treatment modalities that overcome stalled wound healing in lower extremity wounds are crucial for reducing lower limb amputations, which have a 5-year mortality rate of an astounding 70%. Recent non-comparative studies have shown negative pressure wound therapy with instillation and dwell time (NPWTi-d) using a dressing comprised of reticulated open cell foam with through holes (ROCF-CC) provides favorable clinical outcomes for various wound types, including complex lower extremity wounds. Objective. The objective of this study is to compare NPWTi-d using ROCF-CC dressings (treatment group) with advanced wound dressings (control group) in patients with chronic lower extremity wounds and known systemic risk factors for delayed healing. Materials and Methods. A retrospective assessment was performed for 10 patients with complex lower extremity wounds that underwent an initial debridement and then were treated with either advanced wound dressings (control group; n = 5) or NPWTi-d using ROCF-CC dressings (treatment group; n = 5). Advanced wound dressings were applied to wounds and changed 1 to 3 times per week. Negative pressure wound therapy with instillation and dwell time was applied by instilling normal saline onto wounds, with a dwell time of 20 minutes, followed by continuous negative pressure (-125 mm Hg) for 2 hours. The ROCF-CC dressings were changed every 2 to 3 days. Results. Patients in the treatment group had significantly fewer wound complications (P = .024) and underwent significantly fewer surgical debridements (P = .004) when compared with patients in the control group. All wounds in the treatment group healed without complication, whereas only 2 of the 5 wounds in the control group healed. Demographics and comorbidities were similar between groups. Conclusions. These data further support the use of NPWTi-d with ROCF-CC to help manage complex wounds of the lower limb.
C1 [Cole, Windy] Kent State Univ, Coll Podiatr Med Wound Care, Independence, OH 44242 USA.
C3 University System of Ohio; Kent State University
RP Cole, W (通讯作者)，Kent State Univ, Coll Podiatr Med Wound Care, Wound Care Res, 6000 Rockside Woods Blvd, Independence, OH 44242 USA.
EM drwec@yahoo.com
CR Blalock L, 2019, WOUNDS, V31, P55
   Cole WE, EPLASTY
   Feinglass J, 2001, SURGERY, V130, P21, DOI 10.1067/msy.2001.115359
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NR 16
TC 3
Z9 3
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUN
PY 2020
VL 32
IS 6
BP 159
EP 163
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA QJ6MV
UT WOS:000619803600003
PM 32335516
DA 2026-07-24
ER

PT J
AU Murphy, P
   Lee, K
   Dubois, L
   DeRose, G
   Forbes, T
   Power, A
AF Murphy, Patrick
   Lee, Kevin
   Dubois, Luc
   DeRose, Guy
   Forbes, Thomas
   Power, Adam
TI Negative pressure wound therapy for high-risk wounds in lower extremity
   revascularization: study protocol for a randomized controlled trial
SO TRIALS
LA English
DT Article
DE Surgical site infection; Vascular surgery; Negative pressure wound
   therapy; Prevena
ID SURGICAL SITE INFECTION
AB Background: Rates of surgical site infections (SSIs) following groin incision for femoral artery exposure are much higher than expected of a clean operation. The morbidity and mortality is high, particularly with the use of prosthetic grafts. The vascular surgery population is at an increased risk of SSIs related to peripheral vascular disease (PVD), diabetes, obesity, previous surgery and presence of tissue loss. Negative pressure wound therapy (NPWT) dressings have been used on primarily closed incisions to reduce surgical site infections in other surgical disciplines. We have not come across any randomized controlled trials to support the prophylactic use of negative pressure wound therapy in high-risk vascular patients undergoing lower limb revascularization.
   Methods/design: In this single-center, prospective randomized controlled trial, patients scheduled for a lower limb revascularization requiring open femoral artery exposure who are at a high risk (BMI > 30 kg/m(2), previous femoral cutdown or Rutherford V or VI category for chronic limb ischemia) will be eligible for the study. A total of 108 groin incisions will be randomized to the use of a negative pressure wound device or standard adhesive gauze dressing. Patients will be followed in hospital and reassessed within the first 30 days postoperatively. The primary outcome is SSI within the first 30 days of surgery and will be determined using the intention-to-treat principle. Secondary outcomes include length of stay, emergency room visits, reoperation, amputation and mortality. A cost analysis will be performed.
   Discussion: The trial is expected to define the role of NPWT in SSI prophylaxis for lower limb revascularization in high-risk vascular patients. The results of the study will be used to inform current best practice for perioperative care and the minimization of SSIs.
C1 [Murphy, Patrick] Univ Western Ontario, Dept Surg, Div Gen Surg, London, ON N6A 5A5, Canada.
   [Lee, Kevin; Dubois, Luc; DeRose, Guy; Power, Adam] Univ Western Ontario, Dept Surg, Div Vasc Surg, London, ON N6A 4G5, Canada.
   [Forbes, Thomas] Univ Toronto, Dept Surg, Div Vasc Surg, Toronto, ON M5T 1P5, Canada.
C3 Western University (University of Western Ontario); Western University
   (University of Western Ontario); University of Toronto
RP Power, A (通讯作者)，Univ Western Ontario, Dept Surg, Div Vasc Surg, 800 Commissioner Rd East, London, ON N6A 4G5, Canada.
EM adam.power@lhsc.on.ca
RI Murphy, Patrick/T-5337-2019
FU Western University (London, ON, Canada)
FX The study is funded by a university grant from the Western University
   (London, ON, Canada) and the NPWT devices are donated by Kinetic
   Concepts Inc. (San Antonio, TX, USA).
CR A Novak, 2014, Open Orthop J, V8, P168, DOI 10.2174/1874325001408010168
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NR 19
TC 13
Z9 13
U1 0
U2 10
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1745-6215
J9 TRIALS
JI Trials
PD NOV 4
PY 2015
VL 16
AR 504
DI 10.1186/s13063-015-1026-1
PG 5
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA CV1IN
UT WOS:000364007500003
PM 26537879
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Schiltz, D
   Wenzel, C
   Brix, E
   Prantl, L
   Taeger, CD
AF Schiltz, Daniel
   Wenzel, Carina
   Brix, Eva
   Prantl, Lukas
   Taeger, Christian D.
TI Salvage of both feet after complete resection of large carcinomas and
   local infection using a new negative pressure wound dressing in
   combination with intermittent instillation therapy
SO JOURNAL OF TISSUE VIABILITY
LA English
DT Article
DE Negative pressure therapy; Instillation; VAC-Therapy; Cleanse-choice;
   Wound conditioning; VAC; VERAFLO
ID VACUUM-ASSISTED CLOSURE; VAC(R) THERAPY
C1 [Schiltz, Daniel; Wenzel, Carina; Brix, Eva; Prantl, Lukas; Taeger, Christian D.] Univ Hosp Regensburg, Dept Plast Hand & Reconstruct Surg, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany.
C3 University of Regensburg
RP Taeger, CD (通讯作者)，Univ Hosp Regensburg, Dept Plast Hand & Reconstruct Surg, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany.
EM christian.taeger@ukr.de
RI prantl, Lukas/AAM-1848-2021; Schiltz, Daniel/HJP-4834-2023
OI prantl, Lukas/0000-0003-2454-2499; Schiltz, Daniel/0000-0003-1096-9336
CR Armstrong DG, 2015, OSTOMY WOUND MANAG, V61, P25
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Esteban MPB, 2013, REV ROL ENFERM, V36, P42
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   D'Hondt M, 2011, TECH COLOPROCTOL, V15, P75, DOI 10.1007/s10151-010-0662-4
   Dow G, 1999, Ostomy Wound Manage, V45, P23
   Dow G, 1999, OSTOMY WOUND MANAG, V45, P29, DOI DOI 10.1074/JBC.M116.721936
   Dow G, 1999, OSTOMY WOUND MANAG, V45, P41
   Fleischmann W, 1998, UNFALLCHIRURG, V101, P649, DOI 10.1007/s001130050318
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   Garcia-Ruano A, 2016, J SURG RES, V206, P292, DOI 10.1016/j.jss.2016.08.030
   Goss S G, 2012, J Am Coll Clin Wound Spec, V4, P74, DOI 10.1016/j.jccw.2014.02.001
   Karaca S, 2015, INT WOUND J, V12, P595, DOI 10.1111/iwj.12234
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Morgante A, 2017, G CHIR, V38, P33, DOI 10.11138/gchir/2017.38.1.033
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Téot L, 2017, INT WOUND J, V14, P842, DOI 10.1111/iwj.12719
   Yang C, 2017, WOUNDS, V29, P240
NR 20
TC 1
Z9 1
U1 0
U2 1
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0965-206X
EI 1876-4746
J9 J TISSUE VIABILITY
JI J. Viab.
PD MAY
PY 2019
VL 28
IS 2
BP 120
EP 123
DI 10.1016/j.jtv.2019.01.002
PG 4
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA HZ2XD
UT WOS:000468711200011
PM 30660464
DA 2026-07-24
ER

PT J
AU Chen, Y
   Almeida, AA
   Mitnovetski, S
   Goldstein, J
   Lowe, C
   Smith, JA
AF Chen, Yi
   Almeida, Aubrey A.
   Mitnovetski, Sergei
   Goldstein, Jacob
   Lowe, Cassie
   Smith, Julian A.
TI Managing deep sternal wound infections with vacuum-assisted closure
SO ANZ JOURNAL OF SURGERY
LA English
DT Article
DE cardiac surgery; deep sternal wound infection; negative pressure
   dressing; vacuum-assisted closure
ID LONG-TERM SURVIVAL; POSTSTERNOTOMY MEDIASTINITIS; CARDIAC-SURGERY;
   RISK-FACTORS; MANAGEMENT; THERAPY; DRAINAGE; RUPTURE; IMPACT; FLAPS
AB Deep sternal wound infection is an uncommon but serious complication of cardiac surgery. Currently, there is no consensus on the optimal management. Vacuum-assisted closure (VAC) has been increasingly used to facilitate wound healing. We aim to review the management of deep sternal wound infections using VAC dressing at our hospital. A retrospective review of consecutive cases of deep sternal wound infections was carried out. Median sternotomies were carried out in 2665 patients between July 2001 and June 2006. Thirty-one patients developed deep sternal wound infections (1.2%). In 26 of these patients, VAC dressing was used either as a stand-alone therapy or as an adjunct to late sternal reconstruction. Deep sternal wound infections were diagnosed on average 13 days from initial surgery. Of the patients treated with VAC dressing, 17 (65%) had stand-alone VAC therapy and 9 had VAC therapy followed by sternal reconstruction. The average duration of VAC dressing in the two groups were 21 and 13 days respectively. There were seven in-hospital deaths, six in the stand-alone VAC group and one death from a reconstructive patient who did not have VAC therapy. The length of hospital stay was similar in two VAC groups (37 vs 45 days). Median follow up was 17 months. No late relapse was found in the stand-alone group. In the intermediate therapy group, two patients had chronic wound sinuses and one patient had a wound collection. Vacuum-assisted closure dressing may be used both as a stand-alone and as an intermediate therapy for deep sternal wound infection. Reconstructive surgery may be avoided in a significant proportion of patients. No late relapse has been associated with VAC use.
C1 [Chen, Yi; Almeida, Aubrey A.; Mitnovetski, Sergei; Goldstein, Jacob; Lowe, Cassie; Smith, Julian A.] Monash Univ, Cardiothorac Surg Unit, Monash Med Ctr, Melbourne, Vic 3004, Australia.
   [Almeida, Aubrey A.; Goldstein, Jacob; Smith, Julian A.] Monash Univ, Dept Surg, Melbourne, Vic 3004, Australia.
C3 Monash University; Monash University
RP Chen, Y (通讯作者)，Monash Med Ctr, Cardiothorac Surg Unit, 246 Clayton Rd, Clayton, Vic 3168, Australia.
EM chen_yi11@hotmail.com
OI Smith, Julian/0000-0003-1244-4277
CR Abboud CS, 2004, ANN THORAC SURG, V77, P676, DOI 10.1016/S0003-4975(03)01523-6
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NR 20
TC 19
Z9 21
U1 0
U2 0
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 1445-1433
J9 ANZ J SURG
JI ANZ J. Surg.
PD MAY
PY 2008
VL 78
IS 5
BP 333
EP 336
DI 10.1111/j.1445-2197.2008.04467.x
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 282HO
UT WOS:000254558700007
PM 18380722
DA 2026-07-24
ER

PT J
AU Gritsiuta, AI
   Reep, G
   Parupudi, S
   Petrov, RV
AF Gritsiuta, Andrei I.
   Reep, Gabriel
   Parupudi, Sreeram
   Petrov, Roman V.
TI Optimizing the management of anastomotic leaks after esophagectomy: a
   narrative review of salvage strategies and outcomes
SO JOURNAL OF GASTROINTESTINAL SURGERY
LA English
DT Review
DE Anastomotic leak; Esophageal cancer; Esophagectomy; Self-expanding metal
   stents; Vacuum-assisted closure
ID GASTROINTESTINAL PERFORATIONS; ENDOSPONGE THERAPY; SURGICAL-TREATMENT;
   STENT MIGRATION; COMPLICATIONS; EFFICACY; SURGERY; CLOSURE;
   PHARYNGOSTOMY; RESECTION
AB Background: Anastomotic leaks (ALs) after esophagectomy remain a major postoperative complication, leading to increased morbidity, prolonged hospital stays, and higher mortality. Despite advancements in surgical techniques and perioperative care, AL management lacks standardized protocols. This review aimed to evaluate current salvage strategies, including conservative, endoscopic, and surgical approaches, to optimize outcomes and reduce complications. Methods: A comprehensive literature search was conducted using PubMed, Scopus, Cochrane Library, and Google Scholar databases to identify studies published between 2000 and 2025 on AL management after esophagectomy. Peer-reviewed clinical trials, guidelines, and expert consensus reports were reviewed, focusing on minimally invasive and surgical interventions, patient outcomes, and emerging treatment strategies. Results: AL management strategies were classified into 3 primary approaches. Conservative management includes nutritional support, antibiotic therapy, and percutaneous drainage, particularly for contained leaks. Endoscopic interventions, such as self-expanding metal stents and endoscopic vacuum-assisted closure, have shown high success rates, with vacuum-assisted closure achieving superior closure outcomes. Hybrid techniques, including stent-over-sponge and vacuum-assisted closure-stent, are emerging as promising alternatives. Surgical interventions remain the gold standard for severe or refractory leaks with options, including primary repair, esophageal diversion, and delayed conduit reconstruction. Conclusion: A multidisciplinary approach is crucial for optimizing AL management, incorporating enhanced recovery protocols, early risk assessment, and individualized treatment plans. Endoscopic techniques have reduced the need for surgical revisions, but surgical intervention remains necessary for severe cases. Future research should focus on refining treatment algorithms, integrating novel technologies, and establishing standardized guidelines to improve patient survival and quality of life. (c) 2025 Society for Surgery of the Alimentary Tract. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
C1 [Gritsiuta, Andrei I.; Petrov, Roman V.] Univ Texas Med Branch, Dept Surg, Div Cardiovasc & Thorac Surg, Galveston, TX 77555 USA.
   [Reep, Gabriel; Parupudi, Sreeram] Univ Texas Med Branch, Dept Internal Med, Div Gastroenterol & Hepatol, Galveston, TX USA.
C3 University of Texas System; University of Texas Medical Branch
   Galveston; University of Texas System; University of Texas Medical
   Branch Galveston
RP Gritsiuta, AI (通讯作者)，Univ Texas Med Branch, Dept Surg, Div Cardiovasc & Thorac Surg, Galveston, TX 77555 USA.
EM gritsiutaai@upmc.edu
RI Petrov, Roman/GXV-4075-2022; Gritsiuta, Andrei/ACD-4576-2022
OI Gritsiuta, Andrei/0000-0003-2265-9992
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NR 87
TC 2
Z9 2
U1 2
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1091-255X
EI 1873-4626
J9 J GASTROINTEST SURG
JI J. Gastrointest. Surg.
PD JUL
PY 2025
VL 29
IS 7
AR 102069
DI 10.1016/j.gassur.2025.102069
EA JAN 2025
PG 12
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 2ST5D
UT WOS:001490432300001
PM 40280464
OA hybrid
DA 2026-07-24
ER

PT J
AU Clare, MP
   Fitzgibbons, TC
   McMullen, ST
   Stice, RC
   Hayes, DF
   Henkel, L
AF Clare, MP
   Fitzgibbons, TC
   McMullen, ST
   Stice, RC
   Hayes, DF
   Henkel, L
TI Experience with the vacuum assisted closure negative pressure technique
   in the treatment of non-healing diabetic and dysvascular wounds
SO FOOT & ANKLE INTERNATIONAL
LA English
DT Article
ID NEUROPATHIC FOOT ULCERS; TOTAL CONTACT CASTS; DEBRIDEMENT
AB The purpose of this study is to report our experience with the Vacuum Assisted Closure (VAC) negative pressure technique in patients with non-healing wounds of the foot, ankle, and lower limb. We retrospectively reviewed 17 patients with non-healing wounds of the lower extremity who underwent treatment using the Vacuum Assisted Closure (VAC) device. Thirteen of 17 (76%) had diabetes mellitus, nine of whom were insulin-dependent, and 10 of whom had associated peripheral neuropathy. Eight of 17 (47%) had severe peripheral vascular disease. All had failed previous management with serial wound debridements and dressing changes; 15 of 17 (88%) had previously completed at least one course of oral antibiotics. Thirteen of 17 (76%) had previously undergone operative irrigation and debridement of the wounds; six of 17 (35%) had previously undergone revascularization procedures of the involved extremity. Five of 17 (29%) had wounds necessitating an amputation procedure prior to the present treatment; seven of 17 (41%) had failed treatment with local growth factors prior to the present treatment. Average length of treatment with the VAC device was 8.2 weeks. Fourteen of 17 (82%) wounds successfully healed; four underwent split-thickness skin grafting for wound closure; four were briefly treated with local growth factors; six were treated with only dressing changes following VAC treatment. Three of 17 (18%) wounds failed VAC treatment; all three patients had diabetes and had wounds located in the midfoot or forefoot; two of three had severe peripheral vascular disease. Our results indicate that the Vacuum Assisted Closure negative pressure technique is emerging as an acceptable option for wound care of the lower extremity. Not all patients are candidates for such treatment; those patients with severe peripheral vascular disease or smaller forefoot wounds may be best treated by other modalities. Larger wounds seem to be better suited for skin grafting or two-stage primary closure.
C1 Gross Iwerson Kratochvil & Klein, Omaha, NE 68124 USA.
RP Fitzgibbons, TC (通讯作者)，Gross Iwerson Kratochvil & Klein, 7710 Mercy Rd,Suite 224, Omaha, NE 68124 USA.
EM drfitz@GIKK.com
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
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NR 17
TC 96
Z9 121
U1 0
U2 7
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1071-1007
EI 1944-7876
J9 FOOT ANKLE INT
JI Foot Ankle Int.
PD OCT
PY 2002
VL 23
IS 10
BP 896
EP 901
DI 10.1177/107110070202301002
PG 6
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 603PH
UT WOS:000178568000002
PM 12398140
DA 2026-07-24
ER

PT J
AU Ferdinando, E
   Guerin, L
   Jervis, AO
   Obidigbo, H
AF Ferdinando, Edward
   Guerin, Laura
   Jervis, Aluko O.
   Obidigbo, Hlenrietta
TI Negative-pressure wound therapy and external fixation for infection and
   hematoma after hallux abducto valgus surgery
SO JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION
LA English
DT Article
ID PATIENT; CLOSURE
AB Hematoma refers to the collection or extravasation of blood, usually clotted, in a closed tissue space. It is caused by leakage from local vessels damaged by blunt trauma, local injury, or surgical dissection. In the postoperative phase, a hematoma often results in edema, pain, wound dehiscence, infection, and scarring of the surgical wound. We describe a 44-year-old woman who developed severe complications, including hematoma, abscess, failure of internal fixation, and loss of soft-tissue structures, after hallux abducto valgus surgery. Hospitalization was required for infection control, soft-tissue coverage through negative-pressure wound therapy, and first metatarsophalangeal joint stabilization through external fixation. Early recognition of the signs of infection and hematoma can help decrease the incidence of postoperative complications.
C1 Staten Isl Univ Hosp, Podiatr Residency Program, Dept Surg, Staten Isl, NY USA.
C3 Northwell Health
RP Guerin, L (通讯作者)，970 Bard Ave, Staten Isl, NY 10305 USA.
CR Andros G, 2006, OSTOMY WOUND MANAG, P1
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NR 16
TC 0
Z9 1
U1 0
U2 1
PU AMER PODIATRIC MED ASSOC
PI BETHESDA
PA 9312 OLD GEORGETOWN ROAD, BETHESDA, MD 20814-1621 USA
SN 8750-7315
J9 J AM PODIAT MED ASSN
JI J. Am. Podiatr. Med. Assoc.
PD SEP-OCT
PY 2007
VL 97
IS 5
BP 410
EP 414
DI 10.7547/0970410
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 219KD
UT WOS:000250082600012
PM 17901348
DA 2026-07-24
ER

PT J
AU Kendal, JK
   Slawaska-Eng, D
   Gazendam, A
   Schneider, P
   Wessel, LE
   Ghert, M
   Bernthal, NM
AF Kendal, Joseph K.
   Slawaska-Eng, David
   Gazendam, Aaron
   Schneider, Patricia
   Wessel, Lauren E.
   Ghert, Michelle
   Bernthal, Nicholas M.
CA PARITY Investigators
TI Risk Factors for All-Cause Early Reoperation Following Tumor Resection
   and Endoprosthetic Reconstruction A Secondary Analysis from the PARITY
   Trial
SO JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
LA English
DT Article
ID PRESSURE WOUND THERAPY; KNEE ARTHROPLASTY; MANAGEMENT; INFECTION;
   OUTCOMES; LIMB; LONG; HIP
AB Background:Oncologic resection and endoprosthetic reconstruction of lower-extremity musculoskeletal tumors are complex procedures fraught with multiple modes of failure. A robust assessment of factors contributing to early reoperation in this population has not been performed in a large prospective cohort. The aim of the present study was to assess risk factors for early reoperation in patients who underwent tumor excision and endoprosthetic reconstruction, with use of data from the Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) trial.Methods:Baseline characteristics were assessed, including age, sex, tumor type, tumor location, presence of a soft-tissue mass, diabetes, smoking status, chemotherapy use, and neutropenia. Operative factors were recorded, including operative time, topical antibiotics, silver-coated prosthetics, endoprosthetic fixation, extra-articular resection, length of bone resected, margins, tranexamic acid, postoperative antibiotics, negative-pressure wound therapy, and length of stay. Univariate analysis was utilized to explore the differences between patients who did and did not undergo reoperation within 1 year postoperatively, and a multivariate Cox proportional hazards regression model was utilized to explore the predictors of reoperation within 1 year.Results:A total of 155 (25.7%) of 604 patients underwent & GE;1 reoperation. In univariate analysis, tumor type (p < 0.001), presence of a soft-tissue mass (p = 0.045), operative time (p < 0.001), use of negative-pressure wound therapy (p = 0.010), and hospital length of stay (p < 0.001) were all significantly associated with reoperation. On multivariate assessment, tumor type (benign aggressive bone tumor versus primary bone malignancy; hazard ratio [HR], 0.15; 95% confidence interval [CI], 0.04 to 0.63; p = 0.01), operative time (HR per hour, 1.15; 95% CI, 1.10 to 1.23; p < 0.001), and use of negative-pressure wound therapy (HR, 1.93; 95% CI, 1.30 to 2.90; p = 0.002) remained significant predictors of reoperation within 1 year.Conclusions:Independent variables associated with reoperation within 1 year in patients who underwent tumor resection and endoprosthetic reconstruction included tumor type (benign aggressive bone tumor versus primary bone malignancy), operative time, and use of negative-pressure wound therapy. These results will help to inform patients and surgeons regarding the risk of reoperation by diagnosis and reinforce operative time as a factor influencing reoperation. These results also support further investigation into the use of negative-pressure wound therapy at the time of surgery in this patient population.
C1 [Kendal, Joseph K.; Wessel, Lauren E.; Bernthal, Nicholas M.] Univ Calif Los Angeles, Dept Orthopaed Surg, Santa Monica, CA 90403 USA.
   [Slawaska-Eng, David; Gazendam, Aaron; Schneider, Patricia; Ghert, Michelle] McMaster Univ, Dept Surg, Div Orthopaed Surg, Hamilton, ON, Canada.
C3 University of California System; University of California Los Angeles;
   McMaster University
RP Kendal, JK (通讯作者)，Univ Calif Los Angeles, Dept Orthopaed Surg, Santa Monica, CA 90403 USA.
EM jkendal@mednet.ucla.edu; david.slawaskaeng@medportal.ca;
   aaron.gazendam@gmail.com; schnep@mcmaster.ca; LWessel@mednet.ucla.edu;
   ghertm@mcmaster.ca; NBernthal@mednet.ucla.edu
RI Slawaska-Eng, David/IAQ-6741-2023; Kendal, Joseph/JNE-3674-2023; Ghert,
   Michelle/JZE-1212-2024
OI Slawaska-Eng, David/0000-0001-7535-0193; Kendal,
   Joseph/0000-0001-9440-2294; Wessel, Lauren/0000-0002-6240-5981;
   Bernthal, Nicholas/0000-0003-3338-5878; 
CR Ailaney N, 2021, J ARTHROPLASTY, V36, P2402, DOI 10.1016/j.arth.2020.11.039
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NR 23
TC 8
Z9 8
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0021-9355
EI 1535-1386
J9 J BONE JOINT SURG AM
JI J. Bone Joint Surg.-Am. Vol.
PD JUL 19
PY 2023
VL 105
IS SUPPL 1
SU 1
BP 4
EP 9
DI 10.2106/JBJS.22.00815
PG 6
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA M9RR5
UT WOS:001033518500003
PM 37466573
DA 2026-07-24
ER

PT J
AU Diefenbeck, M
   Mennenga, U
   Gückel, P
   Tiemann, AH
   Mückley, T
   Hofmann, GO
AF Diefenbeck, M.
   Mennenga, U.
   Gueckel, P.
   Tiemann, A. H.
   Mueckley, T.
   Hofmann, G. O.
TI Vacuum-Assisted Closure Therapy for the Treatment of Skin and
   Soft-Tissue Infections. Are Wound Specimens of Use in Planning Secondary
   Wound Closure?
SO ZEITSCHRIFT FUR ORTHOPADIE UND UNFALLCHIRURGIE
LA German
DT Article
DE skin and soft tissue infection (SSTI); vacuum-assisted closure (VAC);
   serial debridements
ID SEALING-TECHNIQUE; OPEN FRACTURES; MANAGEMENT; INSTILLATION; INJURIES;
   COVERAGE; TRIAL; BONE
AB Aim: Vacuum-assisted closure is used frequently for the treatment of skin and soft-tissue infections (SSTI) of the extremities. After debridement and repeated VAC dressing changes, the wounds are closed by secondary suture, split-thickness skin grafts or local flaps. However, no objective parameters describe the time point for secondary wound closure. Our thesis was that negative microbiological results from wound specimens can indicate the time for secondary wound closure.
   Patients and Methods: 24 patients with SSTI of the extremities were treated by serial debridements and VAC therapy and analysed prospectively. Debridements were repeated until the wounds were macroscopically free from signs of infection (good granulation/no necrosis). During each revision specimens were taken for microbiological analysis. Moreover, number of revisions, bacterial cultures, type of wound closure and wound status after 3 years and 5 months on average after the last surgery were analysed.
   Results: 6.3 revisions on average were performed until secondary wound closure was possible. In spite of the absence of macroscopic infection, bacteria were still found in tissue samples from 14 of 24 wounds. 6 wounds were free of bacteria for the first time right before wound closure, 3 wounds had become negative during the treatment. After 3.4 years on average, the wounds of all 18 patients available for examination had healed well and were free from signs of infection.
   Conclusion: Vacuum-assisted closure resulted in clean, good granulating wounds without necrosis. However, in more than half of the wounds bacteria persisted. This bacterial load had no correlation to wound healing and outcome after over 3 years. In conclusion, microbiological tissue samples are not suitable as indicator for the time point of secondary wound closure in SSTI.
C1 [Diefenbeck, M.; Mueckley, T.; Hofmann, G. O.] Univ Jena, Klin Unfall Hand & Wiederherstellungschirurg, D-07747 Jena, Germany.
   [Mennenga, U.; Tiemann, A. H.; Hofmann, G. O.] BG Kliniken Bergmannstrost Halle Saale, Klin Unfall & Wiederherstellungschirurg, Halle, Germany.
   [Gueckel, P.] Exquit, Software Solut, Munich, Germany.
C3 Friedrich Schiller University of Jena
RP Diefenbeck, M (通讯作者)，Univ Jena, Klin Unfall Hand & Wiederherstellungschirurg, Erlanger Allee 101, D-07747 Jena, Germany.
EM michael.diefenbeck@med.uni-jena.de
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NR 28
TC 9
Z9 10
U1 0
U2 2
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 1864-6697
J9 Z ORTHOP UNFALLCHIR
JI Z. Orthop. Unfallchir.
PD JUN
PY 2011
VL 149
IS 3
BP 324
EP 329
DI 10.1055/s-0030-1250694
PG 6
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 778ST
UT WOS:000291726700011
PM 21305454
DA 2026-07-24
ER

PT J
AU Boti, L
   Soloway, L
   Myers, D
   Pillai, D
   Zabihi, J
AF Boti, Leila
   Soloway, Laura
   Myers, Deb
   Pillai, Dinu
   Zabihi, Javad
TI Decreased Health Care Expenditure and Average Length of Therapy With
   Facilitated Transition Discharge Program for Patients Receiving Negative
   Pressure Wound Therapy br
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article; Proceedings Paper
CT Joint Annual Meeting of the Wound-Healing-Society (WHS) / Spring
   Symposium on Advanced Wound Care (SAWC)
CY APR 06-10, 2022
CL ELECTR NETWORK
SP Wound Healing Soc
DE discharge programs; hospital stays; negative pressure wound therapy
AB This study compares LOT between patients discharged from hospitals with FT discharge programs providing NPWT to patients at/before discharge versus those without (non-FT). FT facilities were further segmented: active-FT (>= 1 transition order during past 90 days) versus inactive-FT (FT set up but no orders during past 90 days). There were 82 543 billable orders and 92 008 patients analyzed. LOT was 1.8 days shorter for FT versus non-FT facilities (potential per-patient savings of $5071 for FT facilities). LOT was 1.2 days shorter in active-FT versus inactive-FT facilities. This study shows shorter stays and LOT for patients in facilities actively using FT.
C1 [Boti, Leila; Soloway, Laura; Myers, Deb; Pillai, Dinu; Zabihi, Javad] 3M Hlth Care, St Paul, MN USA.
   [Boti, Leila] 7703 Cypress View, Boerne, TX 78015 USA.
C3 3M
RP Boti, L (通讯作者)，7703 Cypress View, Boerne, TX 78015 USA.
EM lboti@mmm.com
CR Baek H, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0195901
   HCUP Reports. Healthcare Cost and Utilization Project (HCUP), 2017, HCUP REPORTS
   Lagoe RJ, 2021, Case Reports in Clinical Medicine, V10, P160, DOI [10.4236/crcm.2021.106020, 10.4236/crcm.2021.106020, DOI 10.4236/CRCM.2021.106020]
   Park M, 2018, INT J NURS STUD, V87, P69, DOI 10.1016/j.ijnurstu.2018.07.006
   Rojas-García A, 2018, HEALTH EXPECT, V21, P41, DOI 10.1111/hex.12619
   Thorup CB, 2018, INT WOUND J, V15, P707, DOI 10.1111/iwj.12913
NR 6
TC 1
Z9 1
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD DEC
PY 2022
VL 34
IS 12
BP E118
EP E120
DI 10.25270/wnds/22050
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Dermatology; Surgery
GA A0QV4
UT WOS:000952271300002
PM 36645656
DA 2026-07-24
ER

PT J
AU Abu-Baker, A
   Tigaran, AE
   Peligrad, T
   Ion, DE
   Gheoca-Mutu, DE
   Avino, A
   Hariga, CS
   Moraru, OE
   Raducu, L
   Jecan, RC
AF Abu-Baker, Abdalah
   Tigaran, Andrada-Elena
   Peligrad, Teodora
   Ion, Daniela-Elena
   Gheoca-Mutu, Daniela-Elena
   Avino, Adelaida
   Hariga, Cristian-Sorin
   Moraru, Oriana Elena
   Raducu, Laura
   Jecan, Radu-Cristian
TI Exploring an Innovative Approach: Integrating Negative-Pressure Wound
   Therapy with Silver Nanoparticle Dressings in Skin Graft Procedures
SO JOURNAL OF PERSONALIZED MEDICINE
LA English
DT Article
DE chronic wounds; silver nanoparticles; negative wound pressure therapy;
   wound healing
ID C-REACTIVE PROTEIN; CONVENTIONAL THERAPY; FOOT; MECHANISM; EFFICACY;
   OUTCOMES; IMPACT; ULCER
AB Background: Skin grafting is a helpful instrument in a plastic surgeon's arsenal. Several types of dressings were designed to facilitate the process of graft integration. Negative-pressure wound therapy is a proven dressing method, enhancing graft survival through several mechanisms: aspiration of secretions, stimulation of neoangiogenesis, and promotion of an anti-inflammatory environment. Silver nanoparticle dressings also bring multiple benefits by bearing an antimicrobial effect and providing a humid medium, which are favorable for epithelialization. The combination of NPWT (negative-pressure wound therapy) with AgNPs (silver nanoparticles) has not been widely studied. Materials and methods: This study aimed to compare the outcomes of silver nanoparticle sheets with the combination of negative-pressure wound therapy and silver nanoparticle dressings. We conducted a comparative prospective study on 80 patients admitted to the Plastic Surgery Department of "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital between 1st of January 2020 and 31st of December 2022. The study population was randomized to receive either silver nanoparticle dressings or negative-pressure wound therapy (NPWT) combined with silver nanoparticle dressings. Various parameters were monitored, including patient comorbidities and graft-related data such as defect etiology, graft integration, and graft size. Dressings were changed, and graft status was evaluated at 7, 10, and 14 days postoperatively. Additionally, baseline C-reactive protein (CRP) levels were measured before surgery and 7, 10, and 14 days postoperatively. Results: The study demonstrated an enhanced integration of skin grafts at all evaluation stages when employing NPWT combined with AgNPs, particularly evident 10 days post operation. Significant variations in graft integration were also observed based on factors such as diabetes, cardiovascular disease, graft size, or the origin of the grafted defect. Moreover, dynamic C-reactive protein monitoring showed a statistically significant decrease in CRP levels 10 days post operation among patients treated with NPWT in conjunction with silver dressing, consistent with the nearly complete integration of skin grafts at this evaluation threshold. Conclusion: Several factors influence the postoperative evolution of split-skin grafts. Postoperative dressings target local factors to enhance graft integration further. Our research demonstrated that the innovative combination of NPWT-assisted dressings, complemented by a silver nanoparticle sheet, resulted in improved benefits for graft integration and the alleviation of systemic inflammation.
C1 [Abu-Baker, Abdalah; Avino, Adelaida] Carol Davila Univ Med & Pharm, Doctoral Sch, Bucharest 010221, Romania.
   [Abu-Baker, Abdalah; Tigaran, Andrada-Elena; Peligrad, Teodora; Ion, Daniela-Elena; Gheoca-Mutu, Daniela-Elena; Avino, Adelaida; Raducu, Laura; Jecan, Radu-Cristian] Prof Dr Agrippa Ionescu Emergency Clin Hosp, Dept Plast Surg, Bucharest 011356, Romania.
   [Gheoca-Mutu, Daniela-Elena] Carol Davila Univ Med & Pharm, Discipline Anat, Bucharest 010221, Romania.
   [Hariga, Cristian-Sorin] Emergency Clin Hosp, Dept Plast Surg, Bucharest 014461, Romania.
   [Hariga, Cristian-Sorin; Raducu, Laura; Jecan, Radu-Cristian] Carol Davila Univ Med & Pharm, Discipline Plast Surg, Bucharest 010221, Romania.
   [Moraru, Oriana Elena] Carol Davila Univ Med & Pharm, Discipline Cardiovasc Surg, Bucharest 010221, Romania.
   [Moraru, Oriana Elena] Prof Dr Agrippa Ionescu Emergency Clin Hosp, Dept Vasc Surg, Bucharest 011356, Romania.
C3 Carol Davila University of Medicine & Pharmacy; Carol Davila University
   of Medicine & Pharmacy; Carol Davila University of Medicine & Pharmacy;
   Carol Davila University of Medicine & Pharmacy
RP Gheoca-Mutu, DE; Raducu, L (通讯作者)，Prof Dr Agrippa Ionescu Emergency Clin Hosp, Dept Plast Surg, Bucharest 011356, Romania.; Gheoca-Mutu, DE (通讯作者)，Carol Davila Univ Med & Pharm, Discipline Anat, Bucharest 010221, Romania.; Raducu, L (通讯作者)，Carol Davila Univ Med & Pharm, Discipline Plast Surg, Bucharest 010221, Romania.
EM abdalah.abu-baker@drd.umfcd.ro; andrada-elena.tigaran@rez.umfcd.ro;
   teodora.peligrad@rez.umfcd.ro; daniela-elena.ion@rez.umfcd.ro;
   daniela-elena.mutu@umfcd.ro; adelaida.avino@drd.umfcd.ro;
   orianaelenamoraru@umfcd.ro; laura.raducu@umfcd.ro;
   cristian.jecan@umfcd.ro
RI Raducu, Laura/AAS-4867-2021; Tigaran, Andrada Elena/JGD-0035-2023;
   Avino, Adelaida/AEW-1705-2022; Jecan, Cristian Radu/ADU-3815-2022;
   Gheoca Mutu, Daniela Elena/AAQ-5197-2020; Abu-Baker,
   Abdalah/IWM-2121-2023
OI Jecan, Cristian Radu/0000-0002-4294-8911; Gheoca Mutu, Daniela
   Elena/0000-0002-8603-5807; Abu-Baker, Abdalah/0009-0009-7435-7196
FU University of Medicine and Pharmacy Carol Davila
FX No Statement Available
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NR 67
TC 13
Z9 18
U1 1
U2 16
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
EI 2075-4426
J9 J PERS MED
JI J. Pers. Med.
PD FEB
PY 2024
VL 14
IS 2
AR 206
DI 10.3390/jpm14020206
PG 16
WC Health Care Sciences & Services; Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services; General & Internal Medicine
GA IY8A8
UT WOS:001169980600001
PM 38392639
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Pérez, M
   Vicente, M
   Amat, C
   Lahoz, B
   Carrera, L
   Corona, PS
AF Perez, Marta
   Vicente, Matias
   Amat, Carles
   Lahoz, Berta
   Carrera, Lluis
   Corona, Pablo S.
TI Outcomes of a cemented modular rotational-hinge design as the final
   implant in a two-stage replacement due to chronic knee periprosthetic
   joint infection
SO ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
LA English
DT Article
DE Periprosthetic joint infection; Knee arthroplasty; Exchange
   arthroplasty; Two-stage exchange arthroplasty; Hinge knee arthroplasty;
   Incisional closed negative pressure wound therapy
ID ARTHROPLASTY; EXCHANGE; SUCCESS
C1 [Perez, Marta; Vicente, Matias; Amat, Carles; Carrera, Lluis; Corona, Pablo S.] Univ Autnoma Barcelona UAB, Vall dHebron Univ Hosp, Orthopaed Surg Dept, Pg Vall dHebron 119-129, Barcelona 08035, Spain.
   [Perez, Marta; Carrera, Lluis; Corona, Pablo S.] Univ Autnoma Barcelona UAB, Bellaterra, Barcelona, Spain.
   [Vicente, Matias; Amat, Carles; Lahoz, Berta; Carrera, Lluis; Corona, Pablo S.] Vall dHebron Univ Hosp, Orthopaed Surg Dept, Sept & Reconstruct Surg Unit UCSO, Barcelona, Spain.
   [Vicente, Matias; Amat, Carles; Lahoz, Berta; Carrera, Lluis; Corona, Pablo S.] Vall dHebron Res Inst, Musculoskeletal Tissue Engn Grp, Barcelona, Spain.
C3 Hospital Universitari Vall d'Hebron; Hospital Universitari Vall
   d'Hebron; Autonomous University of Barcelona; Hospital Universitari Vall
   d'Hebron; Vall d'Hebron Institut de Recerca (VHIR)
RP Pérez, M (通讯作者)，Univ Autnoma Barcelona UAB, Vall dHebron Univ Hosp, Orthopaed Surg Dept, Pg Vall dHebron 119-129, Barcelona 08035, Spain.; Pérez, M (通讯作者)，Univ Autnoma Barcelona UAB, Bellaterra, Barcelona, Spain.
EM 1590363@uab.cat
RI Corona, Pablo S/F-7968-2012; Amat, Carles/E-9405-2017
OI Corona, Pablo S/0000-0003-4128-3142; Amat, Carles/0000-0002-3057-0595;
   Lahoz, Berta/0000-0003-2649-4136
FU Universitat Autonoma de Barcelona
FX Open Access Funding provided by Universitat Autonoma de Barcelona. This
   work received no outside financial support. The study was conducted as
   part of the routine work of our institution.
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NR 22
TC 1
Z9 1
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0936-8051
EI 1434-3916
J9 ARCH ORTHOP TRAUM SU
JI Arch. Orthop. Trauma Surg.
PD DEC
PY 2024
VL 144
IS 12
SI si
BP 5239
EP 5250
DI 10.1007/s00402-024-05516-x
EA SEP 2024
PG 12
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA T5S3F
UT WOS:001314916500005
PM 39287785
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Uygur, F
   Duman, H
   Ülkür, E
   Çeiköz, B
AF Uygur, Fatih
   Duman, Haluk
   Ulkur, Ersin
   Ceikoz, Bahattin
TI The role of the vacuum-assisted closure therapy in the salvage of venous
   congestion of the free flap: case report
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Free flap; VAC therapy; Venous congestion
ID ISCHEMIA
AB Indications for vacuum-assisted closure (VAC) therapy described generally include acute, chronic, traumatic wounds and ulcers. Recent studies related to investigating new applications of VAC therapy have begun to be reported at literature in many aspects. We used this technique in a novel area. A 21-year-old man presented who suffered venous congestion in anterolateral thigh fasciocutaneous flap at the postoperative second day. Following two cycles of VAC therapy, 72 hours later, venous congestion disappeared. Application of VAC therapy to the flap helps removal of excess interstitial fluid because of increased pressure gradients. It seems that VAC therapy is an option in venous congestion when the interstitial pressure rises above capillary pressure.
C1 [Uygur, Fatih; Duman, Haluk; Ulkur, Ersin; Ceikoz, Bahattin] Haydarpasa Training Hosp, Dept Plast & Reconstruct Surg, Istanbul, Turkey.
   [Uygur, Fatih; Duman, Haluk; Ulkur, Ersin; Ceikoz, Bahattin] Haydarpasa Training Hosp, Burn Unit, Gulhane Mil Med Acad, Istanbul, Turkey.
   [Uygur, Fatih; Duman, Haluk; Ulkur, Ersin; Ceikoz, Bahattin] Haydarpasa Training Hosp, Fac Med, Istanbul, Turkey.
C3 Istanbul Haydarpasa Numune Training & Research Hospital; Istanbul
   Haydarpasa Sultan Abdulhamid Training & Research Hospital; Gulhane
   Training & Research Hospital; Istanbul Haydarpasa Numune Training &
   Research Hospital; Istanbul Haydarpasa Sultan Abdulhamid Training &
   Research Hospital; Istanbul Haydarpasa Numune Training & Research
   Hospital; Istanbul Haydarpasa Sultan Abdulhamid Training & Research
   Hospital
RP Uygur, F (通讯作者)，Haydarpasa Training Hosp, Dept Plast & Reconstruct Surg, Istanbul, Turkey.
EM fatihuygur@hotmail.com
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NR 15
TC 30
Z9 33
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAR
PY 2008
VL 5
IS 1
BP 50
EP 53
DI 10.1111/j.1742-481X.2007.00362.x
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA V16AT
UT WOS:000207843200009
PM 18179554
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Kutschka, I
   Dziadzka, S
   El Essawi, A
   Flory, PJ
   Harringer, W
AF Kutschka, I
   Dziadzka, S
   El Essawi, A
   Flory, PJ
   Harringer, W
TI Vacuum assisted closure for the treatment of sternal wound infections -
   Rapid infection control and bridging to reconstructive surgery
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nuernberg, GERMANY
ID CARDIAC-SURGERY; MEDIASTINITIS; THERAPY
AB Vacuum Assisted Closure (V.A.C.(R)) is a sound strategy to control severe poststernotomy infection. Secondary re-wiring of the sternal bone or reconstructive surgery may be required later to achieve complete wound closure. Ten patients with severe sternal bone infection underwent initial V.A.C.(R) therapy and delayed surgery for wound closure. Complete wound healing was achieved in all cases. As a case report we describe a patient with right-sided mastectomy and irradiation for breast cancer, who developed severe poststernotomy infection and sternal bone necrosis following CABG. A combination of V.A.C.(R) therapy and surgical reconstruction using a pedicled latissimus dorsi musculocutaneous flap led to complete wound closure.
C1 Klinikum Braunschweig, Abt Herz Thorax & Gefasschirurg, D-38126 Braunschweig, Germany.
   Unfallchirurg Klinikum Braunschweig, Abt Plast Chirurg & Handchirurg, D-38126 Braunschweig, Germany.
RP Kutschka, I (通讯作者)，Klinikum Braunschweig, Abt Herz Thorax & Gefasschirurg, Salzdahlumerstr 90, D-38126 Braunschweig, Germany.
EM ingo.kutschka@t-online.de
RI El-Essawi, Aschraf/AFM-0248-2022
OI Harringer, Wolfgang/0000-0001-8899-4828; Kutschka,
   Ingo/0000-0002-7358-3513
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NR 8
TC 3
Z9 6
U1 0
U2 4
PU JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
PI STUTTGART
PA RUEDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S129
EP S132
DI 10.1055/s-2006-921427
PG 4
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 034DB
UT WOS:000236904100030
PM 16575663
DA 2026-07-24
ER

PT J
AU Dian, D
   Sommer, H
   Wilkowski, R
   Mylonas, I
   Janni, W
   Friese, K
AF Dian, D.
   Sommer, H.
   Wilkowski, R.
   Mylonas, I.
   Janni, W.
   Friese, K.
TI First Experiences with Vacuum-Assisted Closure (VAC) as Alternative
   Treatment Method to Repair Defects of the Thoracic Wall after Recurrence
   of Breast Cancer
SO GEBURTSHILFE UND FRAUENHEILKUNDE
LA German
DT Article
DE breast; cancer; recurrence; vacuum assisted closure; VAC
ID PROSPECTIVE RANDOMIZED-TRIAL; WOUND THERAPY
AB Loco-regional recurrence of mastocarcinoma is associated with a bad prognosis. Extensive and complicated surgical treatment using autologous tissue is often necessary to repair and cover defects.
   Patients and Methods: Three female patients were treated with the VAC system after undergoing resection for recurrence. In all cases local primary coverage was not possible.
   Results: In the described cases the wounds healed well during the postoperative phase. No problems with the inlying VAC systems occurred during radiation treatment or during chemotherapy.
   Conclusion: Vacuum-assisted wound closure is a potential option which allows the surgeon to avoid autologous tissue treatment in cases with extensive loco-regional recurrence.
C1 [Dian, D.; Sommer, H.; Mylonas, I.; Janni, W.; Friese, K.] Univ Frauenklin Munchen, D-80337 Munich, Germany.
C3 University of Munich
RP Dian, D (通讯作者)，Univ Frauenklin Munchen, Campus Innenstadt Maistr 11, D-80337 Munich, Germany.
EM darius.dian@med.uni-muenchen.de
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NR 13
TC 0
Z9 0
U1 0
U2 0
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0016-5751
J9 GEBURTSH FRAUENHEILK
JI Geburtshilfe Frauenheilkd.
PD JAN
PY 2009
VL 69
IS 1
BP 50
EP 54
DI 10.1055/s-2008-1039242
PG 5
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 407PF
UT WOS:000263376100008
DA 2026-07-24
ER

PT J
AU Youn, HC
   Kwon, SH
AF Youn, Hyo Chul
   Kwon, Se Hwan
TI Endoscopic Vacuum-Assisted Closure (E-VAC) Treatment in a Patient with
   Delayed Anastomotic Perforation following a Perforated Gastric Conduit
   Repair after an Ivor-Lewis Esophagectomy
SO ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
DE esophageal neoplasm; esophagectomy; anastomotic leakage; endoscopy
ID MANAGEMENT; LEAKAGE
AB It has been reported that intrathoracic esophageal leakages occur at a rate of 4%-17% after Ivor-Lewis esophagectomy. There has been no consensus on a specific treatment for the post-operative anastomotic leakage. Recently, endoscopic vacuum-assisted closure (E-VAC) has been introduced as a novel treatment for the post-operative anastomotic leakage. We herein report the case of a patient with early perforation of the gastric conduit followed by late esophagogastric anastomotic leakage who was successfully treated with early surgical repair and subsequent E-VAC. The patient had been previously diagnosed with achalasia and squamous cell carcinoma of the esophagus and undergone an Ivor-Lewis esophagectomy.
C1 [Youn, Hyo Chul] Kyung Hee Univ Hosp, Dept Thorac & Cardiovasc Surg, Seoul, South Korea.
   [Kwon, Se Hwan] Kyung Hee Univ Hosp, Dept Radiol, Seoul, South Korea.
C3 Kyung Hee University; Kyung Hee University Hospital; Kyung Hee
   University; Kyung Hee University Hospital
RP Youn, HC (通讯作者)，Kyung Hee Univ, Dept Thorac & Cardiovasc Surg, Med Ctr, 130-702 Hoegi Dong, Seoul, South Korea.
EM younhc71@hanmail.net
RI Kwon, Se Hwan/ABF-3209-2020
OI Kwon, Se Hwan/0000-0002-7777-8422
CR Alanezi Khaled, 2004, Ann Thorac Cardiovasc Surg, V10, P71
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   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
NR 11
TC 10
Z9 12
U1 0
U2 0
PU MEDICAL TRIBUNE INC
PI TOKYO
PA ED COMM ANNALS THORACIC CARDIOVASCULAR SURG, 2-1-30 KUDAN MINAMI,
   CHIYODA-KU, TOKYO, 102-0074, JAPAN
SN 1341-1098
EI 2186-1005
J9 ANN THORAC CARDIOVAS
JI Ann. Thorac. Cardiovasc. Surg.
PY 2016
VL 22
IS 6
BP 363
EP 366
DI 10.5761/atcs.cr.15-00305
PG 4
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA EH4QH
UT WOS:000391755200007
PM 27075934
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Daldal, I
   Senkoylu, A
AF Daldal, Ismail
   Senkoylu, Alpaslan
TI Strategies of management of deep spinal infection: from irrigation and
   debridement to vacuum-assisted closure treatment
SO ANNALS OF TRANSLATIONAL MEDICINE
LA English
DT Review
DE Scoliosis; wound infection; spinal instrumentation; surgical site
   infections
ID SURGICAL SITE INFECTIONS; RISK-FACTORS; WOUND-INFECTION; VANCOMYCIN
   POWDER; FUSION; INSTRUMENTATION; IMPLANT
AB Postoperative surgical site problems (PSSPs) following spinal surgery may lead to patient mortality, increased treatment costs and possible recurrent medical interventions. Despite efforts to reduce spinal surgery-related infection rates, complications are common and significantly increased by patient comorbidities. Since PSSPs occur regardless of deterrent measures, it is essential to distinguish the related risk factors. Different treatment conventions for PSSPs, for example, antibiotic treatment, debridement, soft tissue care and removal of implants have been prescribed with blended outcomes. The utilization of the wound vacuum-assisted closure (VAC) system has gained increasing popularity in the management of deep wound infections after deformity surgery.
C1 [Daldal, Ismail] Lokman Hekim Akay Hosp, Dept Orthopaed & Traumatol, Ankara, Turkey.
   [Senkoylu, Alpaslan] Gazi Univ, Dept Orthopaed & Traumatol, TR-06510 Ankara, Turkey.
C3 Lokman Hekim Hospital; Gazi University
RP Senkoylu, A (通讯作者)，Gazi Univ, Dept Orthopaed & Traumatol, TR-06510 Ankara, Turkey.
EM drsenkoylu@gmail.com
RI daldal, ismail/AAM-3002-2021
CR [Anonymous], 2015, User Guide for the 2015 ACS NSQIP Participant Use Data File (PUF)]
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   Janjua MB, 2019, PEDIATR NEUROSURG, V54, P108, DOI 10.1159/000496693
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NR 33
TC 14
Z9 19
U1 0
U2 4
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2305-5839
EI 2305-5847
J9 ANN TRANSL MED
JI ANN. TRANSL. MED.
PD JAN
PY 2020
VL 8
IS 2
SI SI
AR 33
DI 10.21037/atm.2019.11.60
PG 7
WC Oncology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Research & Experimental Medicine
GA KD0JJ
UT WOS:000507557700013
PM 32055624
OA Green Published, gold
DA 2026-07-24
ER

PT J
AU Lakha, AS
   Neves, S
   Alemour, Y
   McGivern, H
   Gordon-Weeks, A
AF Lakha, Adil S.
   Neves, Salma
   Alemour, Younis
   McGivern, Hannah
   Gordon-Weeks, Alex
TI Negative-pressure wound therapy in thoracic and abdominal surgery:
   meta-analysis of randomized trials
SO BJS OPEN
LA English
DT Review
ID SURGICAL-SITE INFECTION; HIGH-RISK; CESAREAN DELIVERY; FINANCIAL IMPACT;
   OBESE WOMEN; COMPLICATIONS; LAPAROTOMY; PREVENTION; INCISIONS
AB Background Around 30 000 patients undergo emergency laparotomy in the UK each year, and a similar number of patients undergo open cardiothoracic surgery. Surgical site infection is a common complication associated with increased morbidity, prolonged hospital stay, and higher healthcare costs. Negative-pressure wound therapy has been proposed as a prophylactic strategy to reduce wound complications, but trial evidence has been inconsistent.Methods This systematic review and meta-analysis was carried out using PRISMA guidelines and was registered prospectively in PROSPERO (CRD420251010516). A literature search was carried out in March 2025 (updated December 2025), and titles and abstracts were screened against predefined inclusion criteria. Trials assessing patients undergoing open thoracic or abdominal surgery for any indication in adult patients assessing the risk of surgical site infection as an outcome were included. Quality assessment was performed using Cochrane's risk-of-bias 2 tool. Summary statistics for outcomes of interest underwent meta-analyses to a confidence interval of 95% and are presented as forest plots.Results Some 12 427 patients across 45 randomized trials in abdominal and thoracic surgery were included for analysis. Negative-pressure wound therapy significantly reduced surgical site infection compared with standard dressings (odds ratio (OR) 0.53, 95% confidence interval 0.42 to 0.66). The effect was consistent across commercial devices (PICO (TM) and Prevena (TM)). Negative-pressure wound therapy was associated with shorter hospital stay (mean difference -1.67 (95% confidence interval -3.19 to -0.16) days), but not with reduced risk of organ/space infection (OR 0.92, 0.67 to 1.25), wound dehiscence, or reoperation. Only three studies included thoracic surgery and no significant difference in surgical site infection was found (OR 0.44, 0.00 to 45.25). Publication bias was detected; trim-and-fill analysis attenuated but did not eliminate the benefit (adjusted OR 0.70, 0.54 to 0.90). Adverse events and patient-reported outcomes were reported infrequently, and showed no consistent differences.Conclusion Negative-pressure wound therapy was associated with a nearly 50% reduction in SSI and shorter hospital stay after open abdominal surgery, with consistent benefit across device types. However, evidence of publication bias, and limited long-term and patient-reported outcome data suggest that effect size may be overestimated. Selective use in high-risk patients is supported.
   This systematic review and meta-analysis of 45 randomized trials including over 12 000 patients found that closed-incision negative-pressure wound therapy (NPWT) significantly reduces surgical site infections (SSIs) and shortens hospital stay following open abdominal surgery, with consistent effects across device types. No benefit was observed for organ/space infection, fascial dehiscence or reoperation, and evidence of publication bias suggests that, although the magnitude of benefit may be overestimated, the reduction in SSI remains statistically significant when adjusted for this. These findings support selective use of NPWT in high-risk patients, while underscoring the need for cost-effectiveness analyses and long-term outcome data.
C1 [Lakha, Adil S.; Gordon-Weeks, Alex] Univ Oxford, Nuffield Dept Surg Sci, Oxford, England.
   [Lakha, Adil S.; Gordon-Weeks, Alex] Oxford Univ Hosp NHS Fdn Trust, Dept Hepatobiliary & Pancreat Surg, Oxford, England.
   [Neves, Salma] Thames Valley Fdn Sch, Oxford, England.
   [Alemour, Younis] Univ Oxford, Bodleian Healthcare Lib, Oxford, England.
   [McGivern, Hannah] Sorbonne Univ, Dept Integrat Biol, Paris, France.
C3 University of Oxford; Oxford University Hospitals NHS Foundation Trust;
   University of Oxford; Sorbonne Universite
RP Lakha, AS (通讯作者)，Univ Oxford, John Radcliffe Hosp, Nuffield Dept Surg Sci, Headley Way, Oxford OX3 9DU, England.
EM asl48@cantab.ac.uk
RI Lakha, Adil/LZI-2877-2025
FU National Institute for Health Research (NIHR)
FX A.S.L. is supported by a National Institute for Health Research (NIHR)
   Academic Clinical Fellowship (2024-27). The views expressed are those of
   the author(s) and not necessarily those of the NIHR or the Department of
   Health and Social Care.
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NR 73
TC 0
Z9 0
U1 2
U2 2
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 2474-9842
J9 BJS OPEN
JI BJS Open
PD JUN
PY 2026
VL 10
IS 3
AR zrag027
DI 10.1093/bjsopen/zrag027
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA IE2KZ
UT WOS:001769599800001
PM 42159327
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Deng, CL
   Wang, LY
   Feng, JW
   Lu, F
AF Deng, Chengliang
   Wang, Liangyue
   Feng, Jingwei
   Lu, Feng
TI Treatment of human chronic wounds with autologous extracellular
   matrix/stromal vascular fraction gel: A STROBE-compliant study
SO MEDICINE
LA English
DT Article
DE adipose-derived stem cell; extracellular matrix; negative pressure wound
   therapy; stromal vascular fraction; wound healing
ID MESENCHYMAL STEM-CELLS; VENOUS LEG ULCERS; ADIPOSE; THERAPY; SKIN; RAT;
   DIFFERENTIATION; THERAPEUTICS; REGENERATION; PROGENITOR
AB Stem cell therapy is considered as the most promising treatment for chronic wounds. Extracellular matrix/stromal vascular fraction gel (ECM/SVF gel), an adipose-derived stem cell-based cytotherapy, has shown healing potential in experimental wounds in animal models. However, the effects of ECM/SVF gel on human chronic wounds have not been investigated. The aim of the present study is to investigate the therapeutic effect of ECM/SVF gel on human chronic wounds.Autologous ECM/SVF gel was prepared and used to treat patients with chronic wounds in clinics, with negative pressure wound therapy as the positive control. Wound healing rate per week and histological changes were performed.The average wound healing rate per week in the ECM/SVF gel group was 34.5511.18% compared with 10.16 +/- 2.67% in the negative pressure wound therapy group (P<.001). Histological analysis with hematoxylin and eosin, Masson's trichrome staining, and CD31 immunohistochemistry showed less lymphocyte infiltration, more collagen accumulation, and more newly formed vessels in the ECM/SVF gel group treated skins compared to the control.ECM/SVF gel is an effective therapeutic option for chronic wound healing in clinics.
C1 [Deng, Chengliang] Zunyi Med Coll, Affiliated Hosp, Dept Plast Surg, Zunyi, Guizhou, Peoples R China.
   [Deng, Chengliang; Wang, Liangyue; Feng, Jingwei; Lu, Feng] Southern Med Univ, Nanfang Hosp, Dept Plast Surg, 1838 Guangzhou North Rd, Guangzhou 510515, Guangdong, Peoples R China.
C3 Zunyi Medical University; Southern Medical University - China
RP Lu, F (通讯作者)，Southern Med Univ, Nanfang Hosp, Dept Plast Surg, 1838 Guangzhou North Rd, Guangzhou 510515, Guangdong, Peoples R China.
EM doctorlufeng@hotmail.com
FU National Nature Science Foundation of China [81471881, 81660323]
FX This work is supported by National Nature Science Foundation of China
   (81471881, 81660323).
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NR 44
TC 47
Z9 63
U1 0
U2 18
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD AUG
PY 2018
VL 97
IS 32
AR e11667
DI 10.1097/MD.0000000000011667
PG 7
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GR0ZJ
UT WOS:000442254400014
PM 30095623
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Barker, CS
   Santa Lucia, G
   Brunette, G
   Lee, LW
AF Barker, Catherine S.
   Santa Lucia, Gabriella
   Brunette, Glenda
   Lee, Lara Wine
TI Treatment of Pediatric Pyoderma Gangrenosum With Modified Negative
   Pressure Wound Therapy and Intralesional Corticosteroids A Case Report
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Inflammatory bowel disease; Intralesional corticosteroids; Negative
   pressure wound therapy; Pediatric; Pyoderma gangrenosum
ID MANAGEMENT; SKIN
AB BACKGROUND: Pyoderma gangrenosum (PG) is a rare ulcerative skin disease; its etiology is unknown, though it is often associated with autoimmune diseases. Pyoderma gangrenosum results in significant morbidity and exquisite pain that affects health-related quality of life. Wound healing is delayed, and patients often experience relapse. Pyoderma gangrenosum is susceptible to pathergy and deterioration with surgical intervention or other trauma; therefore, treatment includes atraumatic wound care, infection management, and local or systemic immunosuppression. CASE: We describe the use of modified negative pressure wound therapy (NPWT) with intralesional and topical steroids for the treatment of PG in a 15-year-old female patient with ulcerative colitis and a staged J-pouch ileoanal reconstruction. The patient and her family refused all systemic therapy due to prior steroid-associated weight gain. She was unable to tolerate conscious dressing changes, further complicating the treatment plan. Procedural interventions such as NPWT have been used previously for PG; however, they can cause wound pathergy and subsequent wound deterioration. Modified NPWT in conjunction with topical and intralesional steroids induced wound healing without producing pathergy. CONCLUSION: Timely recognition of PG is crucial to appropriate delivery of care. Modified NPWT and localized corticosteroid treatment were key to promoting wound healing in this case of pediatric PG.
C1 [Barker, Catherine S.; Santa Lucia, Gabriella; Lee, Lara Wine] Med Univ South Carolina, Dept Dermatol & Dermatol Surg, 135 Rutledge Ave,MSC 578, Charleston, SC 29425 USA.
   [Brunette, Glenda] Med Univ South Carolina, Dept Specialty Nursing, Charleston, SC 29425 USA.
C3 Medical University of South Carolina; Medical University of South
   Carolina
RP Barker, CS (通讯作者)，Med Univ South Carolina, Dept Dermatol & Dermatol Surg, 135 Rutledge Ave,MSC 578, Charleston, SC 29425 USA.
EM cshirer@ymail.com
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NR 16
TC 0
Z9 0
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD SEP-OCT
PY 2022
VL 49
IS 5
BP 488
EP 491
DI 10.1097/WON.0000000000000904
PG 4
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 4N3SW
UT WOS:000853939700015
PM 36108234
DA 2026-07-24
ER

PT J
AU Matthews, MR
   Fernández, LG
   Hermans, MHE
   Chakravarthy, D
AF Matthews, Marc R.
   Fernandez, Luis G.
   Hermans, Michel H. E.
   Chakravarthy, Debashish
TI The Efficient Application of Instilling Negative Pressure Wound Therapy
   With a Hypochlorous Acid-Preserved Wound Cleanser: A Case Series and
   Practical Advice
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE debridement; pure hypochlorous acid; negative pressure wound therapy
   with instillation and dwell time
ID CLINICAL RECOMMENDATIONS; INSTILLATION; TRAUMA; DWELL; HOLES
AB Background. The use of negative pressure wound therapy with instillation and dwell time (NPWTi-d) has been shown to be effective in removing nonviable tissue, reducing bioburden, and promoting granulation tissue formation in acute and chronic infected wounds. Objective. To illustrate the clinical efficacy of the use of pure hypochlorous acid (pHA) antimicrobially preserved wound cleansing solution as the instillation fluid for NPWTi-d (NPWTi-d/pHA) in wound bed preparation in patients with complex wounds. Case Report. The treatment protocol for use of NPWTi-d/pHA in preparing wound beds for final closure is demonstrated in 3 illustrative cases of patients with complex wounds resulting from necrotizing infection and trauma with heavy contamination. All 3 patients developed a healthy -appearing wound bed deemed suitable for primary closure an average of approximately 1 month following initial surgical debridement. Conclusion. The cases presented demonstrate the ability of a pHA antimicrobially preserved wound cleansing solution used as the instillation fluid with NPWTi-d to aid in bacterial reduction, mechanical debridement, and promotion of wound healing. Use of NPWTi-d/pHA in these cases of extensive necrotizing infection and posttraumatic injury with heavy contamination allowed for final closure an average of 1 month after initial surgical debridement.
C1 [Matthews, Marc R.] Banner Univ Arizona, Univ Med Ctr, Dept Surg, Div Trauma Surg Crit Care Burns & Acute Care Surg, Tucson, AZ USA.
   [Fernandez, Luis G.] Univ Texas Hlth Sci Ctr, Dept Surg, Div Trauma Surg Surg Crit Care, UT Hlth East Texas, Tyler, TX 75708 USA.
   [Hermans, Michel H. E.] Hermans Med Consulting, Hoorn, Netherlands.
   [Chakravarthy, Debashish] Urgo Med North Amer, Ft Worth, TX USA.
C3 University of Arizona; University of Texas System; University of
   Texas-Health Sciences Center at Tyler (UTHSCT); University of Texas at
   Tyler
RP Fernández, LG (通讯作者)，Univ Texas Hlth Sci Ctr, Dept Surg, Div Trauma Surg Surg Crit Care, UT Hlth East Texas, Tyler, TX 75708 USA.
EM luis.fernandez@uthct.edu
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NR 47
TC 3
Z9 3
U1 0
U2 5
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD MAY
PY 2024
VL 36
IS 5
BP 148
EP 153
DI 10.25270/wnds/21122
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA UJ1Y5
UT WOS:001247610900002
PM 38861209
DA 2026-07-24
ER

PT J
AU Révész, ES
   Altorjay, A
   Montskó, V
   Hangody, L
AF Revesz, Erzsebet Szabone
   Altorjay, Aron
   Montsko, Valeria
   Hangody, Laszlo
TI Effectiveness of negative pressure wound therapy: Minimum five-year
   follow-up and review of the literature
SO JOINT DISEASES AND RELATED SURGERY
LA English
DT Article
DE Efficacy; negative pressure wound therapy; wound management
AB Objectives: In this study, we aimed to assess the effectiveness of negative pressure wound therapy (NPWT) in a five-year patient cohort and to discuss the results in the light of literature data. Patients and methods: Between January 2012 and December 2016, a total of 74 patients (35 males, 39 females; median age: 60 years; range, 20 to 95 years) who received NPWT were retrospectively analyzed. The patients included 49 orthopedic and traumatology, 12 vascular surgery, and 13 general surgery patients. The efficacy of wound healing, bacterial load, and the impact of comorbidities on wound healing were examined. Results: The distribution of wound types varied very widely. Certain comorbidities affected wound healing. In orthopedic traumatology patients, we observed mainly skin flora infection (57.14%), while in surgical and vascular patients, mixed flora (80%) and in many cases poly-resistant pathogens were present (methicillin-resistant Staphylococcus aureus 24%) A total of 43.3% of wounds were completely closed, while 44.6% of patients had a wound healing. Successful skin grafting was performed in 75% of wounds. Conclusion: This technique may be used as widely and as early as possible. However, further large-scale, multi-center, randomized clinical trials are needed worldwide to find a place for this technique in wound care and even in primary care.
C1 [Revesz, Erzsebet Szabone; Altorjay, Aron] St Goerges Hosp, Dept Surg, H-8000 Szekesfehervar, Hungary.
   [Montsko, Valeria] St George Hosp, Septiv, Szekesfehervar, Hungary.
   [Hangody, Laszlo] Uzsoki Hosp, Dept Orthoped & Traumatol, Budapest, Hungary.
   [Hangody, Laszlo] Semmelweis Univ, Dept Traumatol, Budapest, Hungary.
C3 Semmelweis University
RP Révész, ES (通讯作者)，St Goerges Hosp, Dept Surg, H-8000 Szekesfehervar, Hungary.
EM revesze1978@gmail.com
OI Szabone Dr. Revesz, Erzsebet/0000-0002-6054-8508
CR Älgå A, 2022, WORLD J EMERG SURG, V17, DOI 10.1186/s13017-022-00415-1
   Atik OS, 2020, JOINT DIS RELAT SURG, V31, P597, DOI 10.5606/ehc.2020.57896
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   Jensen NM., 2022, J CLIN ORTHOPAEDICS, V24, P101710, DOI [10.1016/j.jcot.2021.101710, DOI 10.1016/J.JCOT.2021.101710]
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   Liu X, 2018, INT J SURG, V53, P72, DOI 10.1016/j.ijsu.2018.02.064
   Liu ZM, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD010318.pub3
   Maruccia M, 2017, BIOMED RES INT, V2017, DOI 10.1155/2017/8395219
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   Revesz Szabone E., 2021, KH, P506
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   Wu LJ, 2022, INT WOUND J, V19, P1449, DOI 10.1111/iwj.13741
NR 17
TC 15
Z9 17
U1 0
U2 4
PU TURKISH JOINT DISEASES FOUNDATION
PI CANKAYA
PA MUSTAFA KEMAL MAHALLESI, DUMLUPINAR BULVARI 274-2 C2 BLOK OFIS, 5,
   CANKAYA, ANKARA, TURKEY
SN 2687-4784
EI 2687-4792
J9 JOINT DIS RELAT SURG
JI Joint Dis. Relat. Surg.
PY 2022
VL 33
IS 1
BP 51
EP 56
DI 10.52312/jdrs.2022.547
PG 6
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 0H8DQ
UT WOS:000778960800008
PM 35361080
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kaufman-Rivi, D
   Hazlett, AC
   Hardy, MA
   Smith, JM
   Seid, HB
AF Kaufman-Rivi, Diana
   Hazlett, Antoinette C.
   Hardy, Mary Anne
   Smith, Jacquelyn M.
   Seid, Heather B.
TI Provider Experiences with Negative-Pressure Wound Therapy Systems
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
DE negative-pressure wound therapy; wound care; medical device reports;
   wound management
AB OBJECTIVE: MedWatch, the Food and Drug Administration's (FDA's) nationwide adverse event reporting system, serves to monitor device performance after a medical device is approved or cleared for market. Through the MedWatch adverse event reporting system, the FDA receives Medical Device Reports of deaths and serious injuries with negative-pressure wound therapy (NPWT) systems, many of which are used in homes and in extended-care facilities. In response to reported events, this study was conducted to obtain additional information about device issues that healthcare professionals face in these settings, as well as challenges that caregivers might encounter using this technology at home. The study was exploratory and descriptive in nature.
   PARTICIPANTS: The FDA surveyed wound care specialists and professional home healthcare providers to learn about users' experiences with NPWT.
   DESIGN: In the first phase of the study, a semistructured questionnaire was developed for telephone interviews and self-administration. In the second phase, a web-based survey was adapted from the semistructured instrument.
   RESULTS: Respondent concerns primarily centered on issues not directly related to the NPWT devices: NPWT prescription, provider education in addition to patient training and appropriate wound management practices, notably ongoing wound assessment, and patient monitoring.
   CONCLUSION: Overall, respondents thought that there was a definite benefit to NPWT, regardless of the care setting, and that it was a safe therapy when prescribed and administered appropriately.
C1 [Kaufman-Rivi, Diana; Hazlett, Antoinette C.] US FDA, Ctr Devices & Radiol Hlth, Off Surveillance & Biometr, Div Patient Safety Partnerships, Silver Spring, MD 20993 USA.
   [Hardy, Mary Anne] Montgomery Hlth Advocates LLC, Derwood, MD USA.
   [Smith, Jacquelyn M.; Seid, Heather B.] Social & Sci Syst Inc, Silver Spring, MD USA.
C3 US Food & Drug Administration (FDA); Social & Scientific Systems
RP Kaufman-Rivi, D (通讯作者)，US FDA, Ctr Devices & Radiol Hlth, Off Surveillance & Biometr, Div Patient Safety Partnerships, Silver Spring, MD 20993 USA.
FU Food and Drug Administration; Social & Scientific Systems, Inc for
   Medical Product Safety Network Activities
FX The authors acknowledge the members of the Food and Drug Administration
   Center for Devices and Radiological Health Workgroup, who throughout the
   project provided excellent analytic, scientific, and clinical expertise.
   Special thanks to study participants and to the professional
   organizations who worked with the Food and Drug Administration and
   Social & Scientific Systems, Inc on this effort, as well as all other
   stakeholders that the authors have collaborated with and will continue
   to work with in the future to ensure the safe use of negative-pressure
   wound therapy. This survey was funded under the Food and Drug
   Administration contract with Social & Scientific Systems, Inc for
   Medical Product Safety Network Activities. Submitted June 27, 2012;
   accepted in revised form October 23, 2012.
CR [Anonymous], 2024, MedWatch: The FDA safety information and adverse event reporting program
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   US Food and Drug Administration (FDA). Center for Devices and Radiological Health, MEDWATCH FORM FDA 35
   World Union of Wound Healing Societies, PRINC BEST PRACT VAC
NR 24
TC 5
Z9 5
U1 0
U2 8
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD JUL
PY 2013
VL 26
IS 7
BP 311
EP 318
DI 10.1097/01.ASW.0000431962.90766.2e
PG 8
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA 299YL
UT WOS:000330431500004
PM 23777881
DA 2026-07-24
ER

PT J
AU Lindholm, VM
   Salminen, AW
   Koskenmies, SJ
   Salmivuori, MK
   Hannula-Jouppi, KSE
   Isoherranen, KM
AF Lindholm, Vivian Mikaela
   Salminen, Anna Wilhelmina
   Koskenmies, Sari Johanna
   Salmivuori, Mari Kaarina
   Hannula-Jouppi, Katariina Sara Eriikka
   Isoherranen, Kirsi Maria
TI An exploratory randomized clinical trial on negative pressure wound
   therapy for lower limb full-thickness skin grafts of dermatosurgical
   patients
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE compression therapy; full-thickness skin graft; negative pressure wound
   therapy; skin cancer
ID SURGICAL-SITE INFECTIONS; SURGERY; REPAIR
AB Full-thickness skin graft (FTSG) reconstructions of lower limbs are especially prone to wound complications. Negative pressure wound therapy (NPWT) enhances wound healing, but no broad evidence exists if it promotes graft take of lower leg FTSGs. In this investigator-initiated, prospective, randomised and controlled trial, 20 patients with ambulatory FTSG reconstruction for lower limb skin cancers were randomised for postoperative treatment with either NPWT, or conventional dressings. As outcomes, adherence of the skin graft 1 week postoperatively, any wound complications within 3 months, including >= 3 weeks delayed wound healing, and the number of additional postoperative visits were compared. In both groups, grafts adhered equally well (p = 0.47); 80% of NPWT-treated and 100% of control group grafts adhered >90%. There was no significant difference in the number of postoperative complications/delayed wound healing (p = 0.65); 70% of patients in the NPWT and 50% in the control group developed a wound complication. Both groups had an equal number of patients with at least three additional control visits (p = 1.0). The study was discontinued after 20 patients were recruited, as no benefit from NPWT was seen. To conclude, the study showed no benefit from NPWT for lower limb FTSGs.
C1 [Lindholm, Vivian Mikaela; Salminen, Anna Wilhelmina; Koskenmies, Sari Johanna; Salmivuori, Mari Kaarina; Hannula-Jouppi, Katariina Sara Eriikka; Isoherranen, Kirsi Maria] Univ Helsinki, ERN Skin Ctr, Dept Dermatol & Allergol, Helsinki, Finland.
   [Lindholm, Vivian Mikaela; Salminen, Anna Wilhelmina; Koskenmies, Sari Johanna; Salmivuori, Mari Kaarina; Hannula-Jouppi, Katariina Sara Eriikka; Isoherranen, Kirsi Maria] Helsinki Univ Hosp, Helsinki, Finland.
   [Hannula-Jouppi, Katariina Sara Eriikka] Folkhalsan Res Ctr, Helsinki, Finland.
   [Hannula-Jouppi, Katariina Sara Eriikka] Univ Helsinki, Stem Cells & Metab Res Program, Res Programs Unit, Helsinki, Finland.
C3 University of Helsinki; University of Helsinki; Helsinki University
   Central Hospital; Folkhalsan Research Center; University of Helsinki
RP Lindholm, VM (通讯作者)，HUS Iho jaallergiasairaala, Meilahdentie 2, Helsinki 00250, Finland.
EM vivian.lindholm@helsinki.fi
OI Salminen, Anna/0000-0002-4074-7956
FU Inflammation Center, Helsinki University Hospital; The Clinical Research
   Institute HUCH, Helsinki University Hospital
FX This non-sponsored investigator-initiated study was supported by the
   Clinical Research Institute Helsinki University Hospital (HUS) and HUS's
   Inflammation Center. The funders did not have any impact on study
   design, data collection, data analysis, manuscript preparation, or
   publication decisions.
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NR 24
TC 2
Z9 3
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2024
VL 21
IS 6
AR e14911
DI 10.1111/iwj.14911
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA DS3FY
UT WOS:001690890200001
PM 38831721
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Gong, SY
   Yang, J
   Lu, TT
   Tian, HW
   Huang, YX
   Song, SM
   Lei, CN
   Yang, WW
   Yang, KH
   Guo, TK
AF Gong, Shiyi
   Yang, Jia
   Lu, Tingting
   Tian, Hongwei
   Huang, Yunxia
   Song, Shaoming
   Lei, Caining
   Yang, Wenwen
   Yang, Kehu
   Guo, Tiankang
TI Incisional negative pressure wound therapy for clean-contaminated wounds
   in abdominal surgery: a systematic review and meta-analysis of
   randomized controlled trials
SO EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
LA English
DT Review
DE Negative-pressure wound therapy; surgical site infection;
   clean-contaminated wounds; randomized controlled trials; meta-analysis
ID SURGICAL SITE INFECTION; COMPLICATIONS; PREVENTION; MANAGEMENT;
   LAPAROTOMY; GUIDELINE; IMPACT
AB Objective The role of incisional negative-pressure wound therapy (iNPWT) in preventing surgical site infections (SSIs) in clean-contaminated abdominal wounds is still controversial. This meta-analysis was performed to evaluate whether the use of iNPWT could reduce SSIs and other complications in clean-contaminated abdominal surgery. Methods The authors searched PubMed, EMBASE, Cochrane library, and Web of Science from database inception to 23 January 2021 for randomized controlled trials (RCTs). They assessed the risk of bias using the Cochrane Collaboration risk of bias tool and conducted a meta-analysis using RevMan 5.4. Results Eleven RCTs, including 4112 patients, were analyzed, of which 2057 were treated with iNPWT and 2055 with standard dressings. The SSI rates (OR = 0.76, 95% CI = 0.61-0.94, P = 0.01), in patients undergoing an iNPWT intervention were significantly lower than those in patients receiving standard dressings. There was no statistically significant difference between the rates of incision dehiscence, seroma, and readmission between groups. Conclusions Application of iNPWT for clean-contaminated wounds in abdominal surgery reduced SSI rates but showed similar rates of wound dehiscence, seroma, and readmission compared with standard dressings.
C1 [Gong, Shiyi; Yang, Jia; Lu, Tingting; Tian, Hongwei; Huang, Yunxia; Song, Shaoming; Lei, Caining; Yang, Wenwen; Guo, Tiankang] Gansu Prov Hosp, 204 West Donggang RD, Lanzhou, Gansu, Peoples R China.
   [Gong, Shiyi; Yang, Jia; Huang, Yunxia; Guo, Tiankang] Ningxia Med Univ, Yinchuan, Ningxia, Peoples R China.
   [Gong, Shiyi; Yang, Jia; Lu, Tingting; Huang, Yunxia; Song, Shaoming; Lei, Caining; Yang, Wenwen; Yang, Kehu; Guo, Tiankang] Gansu Prov Hosp, Inst Clin Res & Evidence Based Med, Lanzhou, Gansu, Peoples R China.
   [Gong, Shiyi; Yang, Jia; Lu, Tingting; Song, Shaoming; Lei, Caining; Yang, Wenwen; Yang, Kehu] Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, Lanzhou, Gansu, Peoples R China.
   [Yang, Kehu] Key Lab Evidence Based Med & Knowledge Translat G, Lanzhou, Gansu, Peoples R China.
C3 Ningxia Medical University; Lanzhou University
RP Guo, TK (通讯作者)，Gansu Prov Hosp, 204 West Donggang RD, Lanzhou, Gansu, Peoples R China.; Yang, KH (通讯作者)，Lanzhou Univ, Evidence Based Med Ctr, 222 West Donggang RD, Lanzhou 730000, Gansu, Peoples R China.
EM kehuyangebm2006@126.com; tiankangguo2020@163.com
RI Lu, Tingting/GZM-8720-2022; Song, Shaoming/AAW-2857-2021
OI Lu, Tingting/0000-0002-6964-3237; Yang, Hehu/0000-0001-7864-3012
FU Key Laboratory of Evidence-Based Medicine and Knowledge Translation
   Foundation of Gansu Province [GSEBMKT-2021KFJJ001]; Gansu Provincial Key
   Laboratory of Molecular Diagnosis and Precision Therapy of Surgical
   Tumors [2019GSZDSYS06]
FX This study was supported by the Key Laboratory of Evidence-Based
   Medicine and Knowledge Translation Foundation of Gansu Province (Grant
   No. GSEBMKT-2021KFJJ001). Gansu Provincial Key Laboratory of Molecular
   Diagnosis and Precision Therapy of Surgical Tumors (Grant No.
   2019GSZDSYS06).
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NR 39
TC 4
Z9 4
U1 1
U2 6
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND
SN 1747-4124
EI 1747-4132
J9 EXPERT REV GASTROENT
JI Expert Rev. Gastroenterol. Hepatol.
PD NOV 2
PY 2021
VL 15
IS 11
BP 1309
EP 1318
DI 10.1080/17474124.2021.1967143
EA AUG 2021
PG 10
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA XC5LZ
UT WOS:000685994800001
PM 34384325
DA 2026-07-24
ER

PT J
AU Son, BS
   Lee, S
   Cho, WH
   Hwang, JJ
   Kim, KD
   Kim, DH
AF Son, Bong Soo
   Lee, Sungsoo
   Cho, Woo Hyun
   Hwang, Jung Joo
   Kim, Kil Dong
   Kim, Do Hyung
TI Modified blowhole skin incision using negative pressure wound therapy in
   the treatment of ventilator-related severe subcutaneous emphysema
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Subcutaneous emphysema; Mechanical ventilation; Negative pressure wound
   therapy
ID HOLES
AB OBJECTIVES: A 2-3-cm blowhole incision in the supraclavicular or infraclavicular area is widely used to eliminate the presence of subcutaneous air in cases of life-threatening subcutaneous emphysema (SE). However, when the patient is supported by mechanical ventilation, it is difficult to eliminate completely such air because mechanical ventilation leads consistently to the formation of large amounts of air. To overcome this, we applied negative pressure wound therapy (NPWT) along with blowhole incisions for the treatment of severe SE.
   METHODS: To evaluate the feasibility of NPWT, we retrospectively analysed the clinical outcomes of 10 patients who developed severe SE during ventilator care and were treated with a modified blowhole incision using NPWT from January 2009 to November 2013.
   RESULTS: All patients showed immediate improvement in SE after NPWT, and no symptom aggravation occurred after NPWT. The mean duration of NPWT was 7.5 +/- 5.1 (range, 3-14) days, and the mean number of dressing changes was 1.5 +/- 0.7 (range, 1-2). There were no blowhole-incision-related wound infections or any other complications.
   CONCLUSIONS: While it is not necessary to apply a blowhole incision with NPWT in all cases of SE, this therapy can be helpful for patients with severe SE associated with mechanical ventilation requiring rapid decompression.
C1 [Son, Bong Soo; Kim, Do Hyung] Pusan Natl Univ, Yangsan Hosp, Dept Thorac & Cardiovasc Surg, Yangsan 626770, Gyeongsangnam D, South Korea.
   [Lee, Sungsoo] Yonsei Univ, Coll Med, Gangnam Severance Hosp, Dept Thorac & Cardiovasc Surg, Seoul, South Korea.
   [Cho, Woo Hyun] Pusan Natl Univ, Yangsan Hosp, Dept Internal Med, Yangsan 626770, Gyeongsangnam D, South Korea.
   [Hwang, Jung Joo; Kim, Kil Dong] Eulji Univ Hosp, Dept Thorac & Cardiovasc Surg, Taejon, South Korea.
C3 Pusan National University; Pusan National University Hospital; Yonsei
   University; Severance Hospital; Yonsei University Health System; Pusan
   National University; Pusan National University Hospital; Eulji
   University; Eulji University Hospital
RP Kim, DH (通讯作者)，Pusan Natl Univ, Yangsan Hosp, Dept Thorac & Cardiovasc Surg, Yangsan 626770, Gyeongsangnam D, South Korea.
EM yumccs@nate.com
OI Son, Bong Soo/0000-0001-6681-6094; Lee, Sungsoo/0000-0001-8998-9510
FU Research Institute for Convergence of Biomedical Science and Technology,
   Pusan National University Yangsan Hospital
FX This work was supported by the Research Institute for Convergence of
   Biomedical Science and Technology, Pusan National University Yangsan
   Hospital.
CR Byun Chun Sung, 2013, Korean J Thorac Cardiovasc Surg, V46, P383, DOI 10.5090/kjtcs.2013.46.5.383
   Dumont SW, 2008, ANAESTHESIA, V63, P212, DOI 10.1111/j.1365-2044.2007.05426.x
   Gregor S, 2008, ARCH SURG-CHICAGO, V143, P189, DOI 10.1001/archsurg.2007.54
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NR 8
TC 18
Z9 22
U1 0
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
EI 1569-9285
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD DEC
PY 2014
VL 19
IS 6
BP 904
EP 907
DI 10.1093/icvts/ivu287
PG 4
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA AY5OR
UT WOS:000347622300004
PM 25164135
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Chen, DZ
   Zhao, Y
   Li, ZH
   Shou, KQ
   Zheng, X
   Li, PC
   Qi, BW
   Yu, AX
AF Chen, Dezhi
   Zhao, Yong
   Li, Zonghuan
   Shou, Kangquan
   Zheng, Xun
   Li, Pengcheng
   Qi, Baiwen
   Yu, Aixi
TI Circulating fibrocyte mobilization in negative pressure wound therapy
SO JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
LA English
DT Article
DE diabetic wound; circulating fibrocyte; negative pressure wound therapy
ID PERIPHERAL-BLOOD FIBROCYTES; ANGIOGENESIS IN-VIVO;
   MYOCARDIAL-INFARCTION; PROGENITOR CELLS; RECEPTOR CXCR4; BONE-MARROW;
   AMD3100; MIGRATION; FIBROSIS; SKIN
AB Non-healing diabetic wounds are difficult to treat. They also create heavy financial burdens for both patients and society. Negative pressure wound therapy (NPWT) has been adopted to treat intractable wounds and has proved to be effective. However, the mechanisms that underlie the effects of this treatment are not entirely understood. Circulating fibrocytes are unique haematopoietic-derived stem cells that have been reported to play a pivotal role in wound healing. Here, we have investigated the effect of NPWT on fibrocyte mobilization and the role of fibrocyte mobilization in the healing of diabetic wounds during NPWT. We show that the NPWT group exhibited 2.6-fold to 12.1-fold greater numbers of tail vein-injected PKH-26-labelled fibrocytes in the diabetic wound sites compared with the control group. We also demonstrate that the full-thickness skin wounds treated with NPWT exhibit significantly reduced mRNA and protein expression, blood vessel density and proliferating cells when exogenous fibrocyte mobilization is inhibited. We speculate that systemic mobilization of fibrocytes during NPWT may be a mechanism for healing intractable wounds in a diabetic rat model experiment and that enhancement of cell mobilization may represent a potential treatment idea for intractable wound healing across all fields of surgery.
C1 [Chen, Dezhi; Zhao, Yong; Li, Zonghuan; Shou, Kangquan; Zheng, Xun; Li, Pengcheng; Qi, Baiwen; Yu, Aixi] Wuhan Univ, Zhongnan Hosp, Dept Orthoped, Wuhan, Hubei, Peoples R China.
C3 Wuhan University
RP Qi, BW; Yu, AX (通讯作者)，Wuhan Univ, Zhongnan Hosp, Dept Orthoped, Wuhan, Hubei, Peoples R China.
EM qbw2004@sina.com; yuaixi@whu.edu.cn
RI /E-6566-2018; Zheng, Xun/JEP-2802-2023; Li, Pengcheng/ABF-5376-2021
FU National Natural Science Foundation of China [81572163]; Hubei National
   Natural Science Fund projects [2014CFB751]; Wuhan Huanghe Elite Program
FX This study was supported by the National Natural Science Foundation of
   China (Grant No. 81572163) and Hubei National Natural Science Fund
   projects (Grant No. 2014CFB751), and Wuhan Huanghe Elite Program. The
   authors would like to acknowledge the Wuhan VSD Medical Science &
   Technology, Co., Ltd. (Wuhan, China) for supplying the vacuum material.
   No conflict of interest exits in the manuscript.
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NR 44
TC 13
Z9 15
U1 0
U2 17
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
EI 1582-4934
J9 J CELL MOL MED
JI J. Cell. Mol. Med.
PD AUG
PY 2017
VL 21
IS 8
BP 1513
EP 1522
DI 10.1111/jcmm.13080
PG 10
WC Cell Biology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Research & Experimental Medicine
GA FC4TG
UT WOS:000406833000008
PM 28211211
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Qiu, B
   Peng, F
   Zhong, J
   Wang, Z
AF Qiu, Bo
   Peng, Fei
   Zhong, Jun
   Wang, Zhe
TI Effect of Negative Pressure Wound Therapy and External Fixation in the
   Treatment of Femur Fracture Complicated by Skin Avulsion: A
   Retrospective Case Series
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE negative pressure wound therapy; external fixation; femoral fracture;
   soft tissue avulsion
AB Objective. The purpose of this study is to explore the clinical effects of negative pressure wound therapy (NPWT) and external fixation in the treatment of femur fracture complicated by skin avulsion. Materials and Methods. Seven cases of comminuted fracture of the femur caused by traffic accidents and complicated by skin avulsion were retrospectively analyzed. After stabilization and treatment of life-threatening injuries, these 7 patients underwent wound debridement, external fixation of the fracture, and coverage of the wound with NPWT. Secondarily, the wounds were covered by skin-grafting. Patients were followed for an average of 12 months. Results. After infection prophylaxis had been implemented and healthy granulation tissue had developed, each patient underwent secondary suture, free-skin grafting, or skin flap transfer. No wound had purulent drainage upon removal of the NPWT 4 to 7 days after placement. Secondary skin grafting was accomplished successfully in all 7 patients. Patients were followed for 6 to 15 months, and all wounds were well healed with no case of nonunion, osteomyelitis, or deformity at the site of union. Conclusion. External fixation with NPWT is effective treatment for femur fracture complicated by skin avulsion. The rate of infection is low and hospital stay is relatively short.
C1 [Qiu, Bo; Peng, Fei; Zhong, Jun; Wang, Zhe] Wuhan Univ, Renmin Hosp, Dept Orthoped, Hubei 430060, Peoples R China.
C3 Wuhan University
RP Qiu, B (通讯作者)，Wuhan Univ, Renmin Hosp, Dept Orthoped, 99 Zhangzhidong Rd, Wuhan 430060, Peoples R China.
EM drqb123@163.com
CR [Anonymous], OSTOMY WOUND MANAG S
   Fang R, 2010, J TRAUMA, V69, pS140, DOI 10.1097/TA.0b013e3181e452a2
   Fang X, 2012, MED SCI MONITOR, V18, pRA49, DOI 10.12659/MSM.882610
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NR 13
TC 1
Z9 1
U1 0
U2 6
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD OCT
PY 2014
VL 26
IS 10
BP 280
EP 284
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA AW2OZ
UT WOS:000346129200002
PM 25855992
DA 2026-07-24
ER

PT J
AU Singh, D
   Gowda, AU
   Chopra, K
   Tholen, M
   Chang, S
   Mavrophilipos, V
   Semsarzadeh, N
   Rasko, Y
   Holton, L
AF Singh, Devinder
   Gowda, Arvind U.
   Chopra, Karen
   Tholen, Michael
   Chang, Sarah
   Mavrophilipos, Vasilios
   Semsarzadeh, Nina
   Rasko, Yvonne
   Holton, Luther, III
TI The Effect of Negative Pressure Wound Therapy With Antiseptic
   Instillation on Biofilm Formation in a Porcine Model of Infected Spinal
   Instrumentation
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE spinal infection secondary spinal surgery; biofilm; negative pressure
   wound therapy
ID IMPLANT INFECTIONS; RESISTANT SURFACES; LUMBAR FUSIONS; CLOSURE;
   MANAGEMENT; BIOMATERIALS; DEVICE
AB Objective. This study evaluates the effect of negative pressure wound therapy with antiseptic instillation (NPWTi) in the clearance of infection and biofilm formation in an in vivo model of infected spinal implants compared to traditional treatment modalities. Materials and Methods. Five pigs underwent titanium rod implantation of their spinous processes followed by injection of 1 x 10(6) CFUs/100 mu L of methicillinresistant Staphylococcus aureus through the fascia at each site. At 1 week postoperatively, an experimental arm of 3 pigs received NPWTi, and a control arm of 2 pigs received wet-to-dry dressings. The persistence of local infection in the experimental group was compared to the control group using tissue cultures. Biofilm development on spinal implants was evaluated using scanning electron microscopy. Results. Mean bacterial count showed a statistical difference between the experimental and the control groups (P < .05). Scanning electron microscopy revealed the presence Of uniform biofilm formation across the surface of control group instrumentation, whereas the experimental group showed interrupted areas between biofilm formations. Conclusion. The authors concluded that NPWTi is associated with decreased bacterial load and biofilm formation compared to wet-to-dry dressings in an in vivo porcine model of infected spinal instrumentation.
C1 [Singh, Devinder; Rasko, Yvonne; Holton, Luther, III] Anne Arundel Med Ctr, Div Plast Surg, 2001 Med Pkwy, Annapolis, MD 21401 USA.
   [Gowda, Arvind U.] Yale Univ, Sch Med, Sect Plast & Reconstruct Surg, New Haven, CT USA.
   [Chopra, Karen; Tholen, Michael; Chang, Sarah; Mavrophilipos, Vasilios; Semsarzadeh, Nina] Univ Maryland, Sch Med, Div Plast & Reconstruct Surg, Baltimore, MD 21201 USA.
   [Chopra, Karen] Johns Hopkins Univ Hosp, Dept Plast & Reconstruct Surg, Baltimore, MD 21287 USA.
C3 Yale University; University System of Maryland; University of Maryland
   Baltimore; Johns Hopkins University; Johns Hopkins Medicine
RP Singh, D (通讯作者)，Anne Arundel Med Ctr, Div Plast Surg, 2001 Med Pkwy, Annapolis, MD 21401 USA.
EM dsingh@aahs.org
RI Singh, Devinder/AAN-4716-2021
FU Acelity
FX Dr. Singh is a consultant for KCI, An Acelity Company (San Antonio, TX).
   This work was supported by a research grant from Acelity. This device is
   not US Food and Drug Administration-approved for the indication that is
   the subject of this manuscript.
CR Ahmed R, 2012, J SPINAL DISORD TECH, V25, P299, DOI 10.1097/BSD.0b013e31821fbf72
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NR 39
TC 13
Z9 15
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUN
PY 2017
VL 29
IS 6
BP 175
EP 180
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA EZ9OP
UT WOS:000405060000005
PM 28267679
DA 2026-07-24
ER

PT J
AU Wilson, K
   Sims, T
AF Wilson, Karie
   Sims, Terran
TI Use of Negative Pressure Wound Therapy in Selected Cases to Facilitate
   Abdominal Wound Healing
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Exposed bowel; Negative pressure wound therapy; NPWT; Peristomal wound;
   Surgical wound dehiscence
ID DEHISCENCE
AB BACKGROUND:Surgical wound dehiscence resulting in exposed bowel increases the risk for development of an enterocutaneous fistula. Consequently, management of exposed bowel in an open wound presents challenges in terms of wound care management. In addition, a surgical wound dehiscence within the peristomal plane of an ileal conduit also creates a complex challenge of maintaining an ostomy pouching system seal.CASES:Case 1 was a patient with peristomal skin complications requiring stoma re-siting and subsequent surgical wound dehiscence at the prior ostomy site. As a result, we addressed wound management in the setting of urinary leakage from the ileal conduit. We used negative pressure wound therapy (NPWT) in the setting of a peristomal dehisced surgical wound to promote healing and optimize peristomal skin health. Case 2 was a patient with an infected surgical incision requiring readmission to hospital and additional surgery. Intra-operative findings revealed a fascial defect with exposed bowel in the wound resulting in unique challenges for wound management. Again, we used NPWT in the setting of exposed bowel to promote granulation and achieve wound closure.CONCLUSION:Research regarding ideal wound management for complex open abdominal wounds with exposed bowel is sparse. These case studies summarize our clinical experience managing complex patients with wound dehiscence and abdominal fascia defects and risk of enterocutaneous fistula formation with NPWT.
C1 [Wilson, Karie] Univ Virginia Hlth Syst, Dept Urol, 1222 Lee St, Charlottesville, VA 22903 USA.
   [Sims, Terran] Univ Virginia, Dept Urol, Charlottesville, VA USA.
C3 University of Virginia; University of Virginia (UVA) Health System;
   University of Virginia
RP Wilson, K (通讯作者)，Univ Virginia Hlth Syst, Dept Urol, 1222 Lee St, Charlottesville, VA 22903 USA.
EM kaw2y@uvahealth.org; tws4m@uvahealth.org
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Chandrasekhar V, 2020, WOUND MANAG PREV, V66, P37, DOI 10.25270/wmp.2020.5.3845
   Cheng Y, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD013710.pub2
   Chetter IC, 2019, INT J NURS STUD, V89, P62, DOI 10.1016/j.ijnurstu.2018.09.011
   Crumley C., 2022, J Wound Ostomy Contin Nurs, V49, P124, DOI [10.1097/WON.0000000000000862, DOI 10.1097/WON.0000000000000862]
   Cwalinski J, 2023, ADV SKIN WOUND CARE, V36, P435, DOI 10.1097/ASW.0000000000000006
   Kim S, 2020, TRIALS, V21, DOI 10.1186/s13063-019-3925-z
   Morinaga K, 2019, ANN PLAS SURG, V82, P213, DOI 10.1097/SAP.0000000000001739
   Richter S, 2013, GASTROENT RES PRACT, V2013, DOI 10.1155/2013/730829
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   Wagner JC, 2021, LANGENBECK ARCH SURG, V406, P2479, DOI 10.1007/s00423-021-02221-w
NR 11
TC 0
Z9 0
U1 2
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD NOV-DEC
PY 2025
VL 52
IS 6
BP 503
EP 509
DI 10.1097/WON.0000000000001233
PG 7
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 9TY3B
UT WOS:001614954000001
PM 41235852
DA 2026-07-24
ER

PT J
AU Chen, CH
   Lee, YC
   Wu, YC
   Lee, CH
   Tsai, YJ
   Liu, YC
   Chen, YH
   Wang, FY
   Chang, SC
AF Chen, Chih-Heng
   Lee, Yi-Ching
   Wu, Yi-Chun
   Lee, Chi-Hung
   Tsai, Yuan-Jen
   Liu, Yung-Ching
   Chen, Yu-Han
   Wang, Fu-Yu
   Chang, Shun-Cheng
TI Multidisciplinary Strategies With Real-Time Fluorescence Images and
   Negative Pressure Wound Therapy to Manage Organ/Space Surgical Site
   Infection in Transplanted Kidneys
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE kidney transplant; renal transplant; organ-space surgical site
   infection; fluorescence imaging; negative-pressure wound therapy;
   bioburden detection
ID CARE; MORTALITY; IMPACT; DEVICE
AB BackgroundSurgical site infection (SSI) after kidney transplantation can severely compromise graft function and prolong hospital stay. Organ/space SSI (osSSI) is a severe type of SSI associated with a significantly higher mortality rate.Aims and ObjectivesThis study aims to provide new strategies of managing (osSSI) after kidney transplant and other high-risk wound infections.MethodThis is a single-center, retrospective study that analyzed the treatment outcomes of 4 patients who developed osSSI after kidney transplant at Shuang-Ho Hospital. The management strategy included real-time fluorescence imaging with MolecuLight, negative-pressure wound therapy (NPWT) with Si-Mesh, and incisional NPWT (iNPWT).ResultThe average length of hospital stay was 18 days (range, 12-23 days). During hospitalization, all patients obtained high-quality debridement under real-time fluorescence image confirmation. The average duration of NPWT was 11.8 days (range, 7-17 days) and iNPWT was 7 days. All transplanted kidneys were preserved with normal function after 6 months of follow-up.ConclusionsOur strategies with real-time fluorescence imaging provide a novel and effective method that can be used in adjunct with the standard of care for managing osSSI after kidney transplantation. More studies are warranted to validate the efficacy of our approach.
C1 [Chen, Chih-Heng; Lee, Yi-Ching] Taipei Med Univ, Coll Med, Sch Med, Taipei, Taiwan.
   [Wu, Yi-Chun] Taipei Med Univ, Shuang Ho Hosp, Integrated Burn & Wound Care Ctr, Dept Surg,Div Plast Surg, New Taipei City, Taiwan.
   [Wu, Yi-Chun] Natl Yang Ming Chiao Tung Univ, Dept Biomed Engn, Taipei, Taiwan.
   [Lee, Chi-Hung] Taipei Med Univ, Shuang Ho Hosp, Div Infect Dis, New Taipei City, Taiwan.
   [Tsai, Yuan-Jen] Taipei Med Univ, Shuang Ho Hosp, New Taipei City, Taiwan.
   [Liu, Yung-Ching] Taipei Med Univ, Shuang Ho Hosp, Dept Internal Med, Div Infect Dis, New Taipei City, Taiwan.
   [Chen, Yu-Han; Wang, Fu-Yu; Chang, Shun-Cheng] Taipei Med Univ, Shuang Ho Hosp, Integrated Burn & Wound Care Ctr, Dept Surg,Div Plast Surg, Taipei, Taiwan.
   [Wang, Fu-Yu] Cabrini Hosp, Melbourne, Vic, Australia.
   [Chang, Shun-Cheng] Taipei Med Univ, Coll Med, Sch Med, Dept Surg, Taipei, Taiwan.
C3 Taipei Medical University; Taipei Medical University; National Yang Ming
   Chiao Tung University; Taipei Medical University; Taipei Medical
   University; Taipei Medical University; Taipei Medical University; Shuang
   Ho Hospital; Cabrini Health; Taipei Medical University
RP Chang, SC (通讯作者)，Taipei Med Univ, Shuang Ho Hosp, Coll Med, Integrated Burn & Wound Care Ctr,Dept Surg,Div Pl, 291 Zhongzheng Rd, New Taipei City 235, Taiwan.
EM b101105115@tmu.edu.tw; markichael86214@gmail.com; 18002@s.tmu.edu.tw;
   15526@s.tmu.edu.tw; uarejudy@gmail.com; yungching@tmu.edu.tw;
   18114@s.tmu.edu.tw; onefuyu@gmail.com; csc901515@gmail.com
RI ; Wu, Yi-Chun/F-7934-2012
OI Tsai, Yuan-Jen/0009-0000-4464-4105; 
CR Abbo LM, 2019, CLIN TRANSPLANT, V33, DOI 10.1111/ctr.13589
   Abecassis M, 2008, CLIN J AM SOC NEPHRO, V3, P471, DOI 10.2215/CJN.05021107
   Astagneau P, 2001, J HOSP INFECT, V48, P267, DOI 10.1053/jhin.2001.1003
   Centers for Disease Control and Prevention, 2021, National Healthcare Safety Network (NHSN) Patient Safety Component Manual
   Chen X, 2018, TRANSPL P, V50, P2479, DOI 10.1016/j.transproceed.2018.04.014
   Coello R, 2005, J HOSP INFECT, V60, P93, DOI 10.1016/j.jhin.2004.10.019
   Cottrill R, 2013, J WOUND CARE, V22, P214, DOI 10.12968/jowc.2013.22.4.214
   Franchin Marco, 2014, Case Rep Transplant, V2014, P742161, DOI 10.1155/2014/742161
   Heap S, 2010, AM J TRANSPLANT, V10, P2370, DOI 10.1111/j.1600-6143.2010.03237.x
   Ho D, 2010, J AM COLL SURGEONS, V211, P99, DOI 10.1016/j.jamcollsurg.2010.02.055
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   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
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   Iesari S, 2017, EXP CLIN TRANSPLANT, V15, P222, DOI 10.6002/ect.2014.0236
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   Markic Dean, 2014, Coll Antropol, V38, P1199
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   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
   Wszola M, 2013, TRANSPLANTATION, V95, P878, DOI 10.1097/TP.0b013e318281b953
   Zanus G, 2011, TRANSPL INT, V24, pe23, DOI 10.1111/j.1432-2277.2010.01198.x
   Zwanenburg PR, 2020, ANN SURG, V272, P81, DOI 10.1097/SLA.0000000000003644
NR 35
TC 2
Z9 2
U1 1
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD APR
PY 2023
VL 90
IS 1
SU 1
BP S60
EP S67
DI 10.1097/SAP.0000000000003379
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA E3WX0
UT WOS:000974892800011
PM 37075295
DA 2026-07-24
ER

PT J
AU Knight, R
   Spoors, LM
   Costa, ML
   Dutton, SJ
AF Knight, Ruth
   Spoors, Louise M.
   Costa, Matthew L.
   Dutton, Susan J.
TI Wound Healing In Surgery for Trauma (WHIST): statistical analysis plan
   for a randomised controlled trial comparing standard wound management
   with negative pressure wound therapy
SO TRIALS
LA English
DT Article
DE Statistical analysis plan; Randomised controlled trial; Negative
   pressure wound therapy; Lower extremity trauma; Surgical site infection
ID TIBIAL PLAFOND; FRACTURES; DISABILITY; FIXATION
AB BackgroundIn the context of major trauma, the rate of wound infection in surgical incisions created during fracture fixation amongst patients with closed high-energy injuries is high. One of the factors which may reduce the risk of surgical site infection is the type of dressing applied over the closed incision. The WHIST trial evaluates the effects of negative-pressure wound therapy (NPWT) compared with standard dressings.Methods/designThe WHIST trial is a multicentre, parallel group, randomised controlled trial. The primary outcome is the rate of deep surgical site infection at 30days after major trauma. Secondary outcomes are measured at 3 and 6months post-randomisation and include the Disability Rating Index, the EuroQoL EQ-5D-5L, the Doleur Neuropathique Questionnaire, a patient-reported scar assessment, and record of complications. The analysis approaches for the primary and secondary outcomes are described here, as are the descriptive statistics which will be reported. The full WHIST protocol has already been published.DiscussionThis paper provides details of the planned statistical analyses for this trial and will reduce the risks of outcome reporting bias and data driven results.Trial registrationInternational Standard Randomised Controlled Trials database, ISRCTN12702354. Registered on 9 December 2015.
C1 [Knight, Ruth; Dutton, Susan J.] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Ctr Stat Med, Oxford Clin Trials Res Unit, Windmill Rd, Oxford OX3 7LD, England.
   [Spoors, Louise M.; Costa, Matthew L.] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford Trauma, Oxford, England.
C3 University of Oxford; University of Oxford
RP Knight, R (通讯作者)，Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Ctr Stat Med, Oxford Clin Trials Res Unit, Windmill Rd, Oxford OX3 7LD, England.
EM ruth.knight@csm.ox.ac.uk
OI Costa, Matthew/0000-0003-3644-1388; Knight, Ruth/0000-0001-6810-2845;
   Dutton, Susan/0000-0003-4573-5257
FU UK National Institute for Health Research Health Technology Assessment
   (HTA) programme [14/199/14]; National Institute for Health Research
   (NIHR) Oxford Biomedical Research Centre; National Institute for Health
   Research [14/199/14] Funding Source: researchfish
FX This project was funded by the UK National Institute for Health Research
   Health Technology Assessment (HTA) programme (project number 14/199/14)
   and was supported by the National Institute for Health Research (NIHR)
   Oxford Biomedical Research Centre. The funder has not been involved in
   the design of the study. The views expressed are those of the authors
   and not necessarily those of the NHS, the NIHR or the Department of
   Health.
CR Achten J, 2018, BMJ OPEN, V8, DOI 10.1136/bmjopen-2018-022115
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NR 28
TC 13
Z9 14
U1 0
U2 8
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1745-6215
J9 TRIALS
JI Trials
PD MAR 28
PY 2019
VL 20
AR 186
DI 10.1186/s13063-019-3282-y
PG 8
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA HS2HB
UT WOS:000463680600002
PM 30922364
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Rycerz, AM
   Slack, P
   McNulty, AK
AF Rycerz, Anthony M.
   Slack, Paul
   McNulty, Amy K.
TI Distribution assessment comparing continuous and periodic wound
   instillation in conjunction with negative pressure wound therapy using
   an agar-based model
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Instillation therapy; Negative pressure wound therapy; V; A; C; Wound
   healing
AB Negative pressure wound therapy (NPWT) is a widely accepted and effective treatment for various wound types, including complex wounds. Negative pressure with instillation was initially used as a gravity-fed system whereby reticulated, open-cell foam in the wound bed was periodically exposed to cycles of soaking with instillation solution followed by NPWT. Recent publications have alluded to positive outcomes with continuous instillation, where fluid is delivered simultaneously with negative pressure. To evaluate the distribution of instillation solutions to wound beds in conjunction with negative pressure, agar-based models were developed and exposed to coloured instillation solutions to identify exposure intensity via agar staining. This model allowed comparison of continuous- versus periodic-instillation therapy with negative pressure. Continuous instillation at a rate of 30 cc/hour with negative pressure showed isolated exposure of instillation fluid to wound beds in agar wound models with and without undermining and tunnelling. In contrast, periodic instillation illustrated uniform exposure of the additive to the entire wound bed including undermined and tunnel areas, with increased staining with each instillation cycle. These findings suggest that periodic instillation facilitates more uniform exposure throughout the wound, including tunnels and undermining, to instillation solutions, thereby providing therapy consistent with the clinician-ordered treatment.
C1 [Rycerz, Anthony M.] Kinet Concepts Inc, AHS Appl Sci, San Antonio, TX 78249 USA.
RP Rycerz, AM (通讯作者)，Kinet Concepts Inc, AHS Appl Sci, 6203 Farinon Dr,Bldg 5, San Antonio, TX 78249 USA.
EM anthony.rycerz@kci1.com
CR Brown P., 2009, QUICK REFERENCE WOUN
   Chatterjee Justin S, 2005, Int Wound J, V2, P258
   Fleischmann W, 2009, INFECTION, V37, P4
   Gabriel A., 2011, MEDSCAPE REFERE 0519
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   Jerome D, 2007, J WOUND OSTOMY CONT, V34, P191, DOI 10.1097/01.WON.0000264834.18732.3b
   Kaehn Kurt, 2009, Br J Nurs, V18, pS6
   Lessing C, 2011, WOUNDS, V23, P309
   McNulty A, 2010, WOUNDS, V22, P114
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Scimeca Christy L, 2010, J Diabetes Sci Technol, V4, P820
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   Wilkes R, 2009, J BIOMECH ENG-T ASME, V131, DOI 10.1115/1.2947358
NR 13
TC 21
Z9 24
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2013
VL 10
IS 2
BP 214
EP 220
DI 10.1111/j.1742-481X.2012.00968.x
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 112DB
UT WOS:000316571100016
PM 22487428
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Kryshtalskyj, MT
   Schell, CD
   Byers, B
   Punja, KG
AF Kryshtalskyj, Michael T.
   Schell, Carson D.
   Byers, Brett
   Punja, Karim G.
TI Negative Pressure Wound Therapy: An Adjunct in Reconstructing Large
   Periocular Defects From Necrotizing Fasciitis
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Necrotizing fasciitis; negative pressure wound therapy; periocular;
   vacuum dressing
AB Purpose:To demonstrate the use of negative pressure wound therapy (NPWT) and other reconstructive techniques in the reconstruction of large tissue defects resulting from periocular necrotizing fasciitis (NF).Methods:Description of technique with 3 illustrative cases and accompanying photographic montage.Results: Technique: Debridement successfully spared post-septal tissues and the lid margin in all cases. Wounds were left open for several days until progressive infection was ruled out. NPWT was applied using hydrophobic, compressible open-pore polyurethane foam, and high-tensile polyvinyl alcohol foam to bolster the tarsorrhaphized eyelid and prevent exposure. A polyurethane, acrylic adhesive was applied overtop, and continuous vacuum at -75 mm Hg via a NPWT unit was applied for 4 to 14 days. Cases of NF included a 65-year-old woman with metastatic lung cancer, a 59-year-old man with diabetes, and a 57-year-old man with progressive preseptal cellulitis. In all cases, NPWT resulted in impressive macrodeformation and granulation of wounds, facilitating further repair using skin grafts, temporalis and orbicularis muscle flaps, and biodegradable temporizing matrix. Considering the initial extent of these wounds, all patients had excellent functional and aesthetic outcomes at 6 to 9 months, and no ophthalmic complications were observed.Conclusions:In this series, NPWT was safe and effective in facilitating complex reconstruction of large periocular tissue defects resulting from necrotizing fasciitis.
C1 [Kryshtalskyj, Michael T.; Byers, Brett; Punja, Karim G.] Univ Calgary, Cumming Sch Med, Dept Surg, Calgary, AB, Canada.
   [Schell, Carson D.] Univ Saskatchewan, Dept Ophthalmol, Saskatoon, SK, Canada.
C3 University of Calgary; University of Saskatchewan
RP Kryshtalskyj, MT (通讯作者)，5 Richard Way SW,Suite 300, Calgary, AB T3E 7M8, Canada.
EM michael.kryshtalskyj@ucalgary.ca; carsonschell@gmail.com;
   brett.byers@albertahealthservices.ca; karimpunja@hotmail.com
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Elner VM, 2006, OPHTHALMOLOGY, V113, P2338, DOI 10.1016/j.ophtha.2006.06.037
   Gillespie JW, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001921
   Kryshtalskyj MT., 2025, Epidemic Group A Streptococcus: a Canadian Series of Periocular Necrotizing Fasciitis
   Lalezari S, 2017, INT WOUND J, V14, P649, DOI 10.1111/iwj.12658
   Luksich JA, 2002, OPHTHALMOLOGY, V109, P2118, DOI 10.1016/S0161-6420(02)01257-5
   Matsuda K, 2015, PRS-GLOB OPEN, V3, DOI 10.1097/GOX.0000000000000264
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Samuelson TW, 2023, J GLAUCOMA, V32, P708, DOI 10.1097/IJG.0000000000002231
   Semlacher RA, 2012, OPHTHAL PLAST RECONS, V28, pE98, DOI 10.1097/IOP.0b013e318236859c
   Shafer B, 2022, OPHTHALMOL THER, V11, P365, DOI 10.1007/s40123-021-00442-2
NR 11
TC 0
Z9 1
U1 3
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD NOV-DEC
PY 2025
VL 36
IS 8
BP e1373
EP e1376
DI 10.1097/SCS.0000000000011935
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 9DH1R
UT WOS:001603605700027
PM 40920746
DA 2026-07-24
ER

PT J
AU Wen, CWY
   Nasir, FABM
   Charl, MK
   Jane, CA
   Abdullah, NSKH
   Ping, LB
   Nair, HKR
AF Wen, Clarissa Wong Yi
   Nasir, Fatini Aina Binti Mohamad
   Charl, Manjageeta Kaur
   Jane, Chew Ait
   Abdullah, Nur Sarimah Kamilia Hoo
   Ping, Lim Boon
   Nair, Harikrishna K. R.
TI Use of a portable negative pressure wound therapy device on a
   hard-to-heal wound with exposed bone: a case study
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE chronic; exposed bone; exudate; hard-to; heal; negative pressure wound
   therapy; wound; wound care; wound dressing; wound healing
AB This case study examines the effectiveness of using negative pressure wound therapy (NPWT) in the management of a hard-to-heal (chronic) wound with exposed ankle bone to reduce associated wound exudate and promote production of granulation tissue. A 60-year-old male patient who was able to attend wound follow-up diligently twice weekly for eight weeks, and weekly thereafter, was selected from a private hospital to take part. During each dressing change, the wound was cleansed with superoxidised cleansing solution, and minimal sharp debridement was performed. In the authors' opinion, the NPWT device used in this study is light and convenient for use in the community or home care setting. The NPWT wound dressing was connected to the NPWT machine via a connecting tube and the device then switched on using the default setting of a negative pressure of 125mmHg. Following the application of the NPWT device, the exposed ankle bone was successfully covered with healthy granulation tissue and healed within 20 weeks with minimal exudate formation in the wound. In the authors' opinion, NPWT is able to promote progress to wound healing; to minimise unnecessary dressing changes and, based on feedback from the patient, is comfortable to wear and when in use.
C1 [Wen, Clarissa Wong Yi] Soza Healthcare Sdn Bhd, Petaling Jaya, Malaysia.
   [Nasir, Fatini Aina Binti Mohamad] Klin TTDI Bangi, Bandar Baru Bangi, Malaysia.
   [Charl, Manjageeta Kaur] Klin Naam Care, Puchong, Malaysia.
   [Jane, Chew Ait] Klin Kesihatan Jelapang, Ipoh, Malaysia.
   [Abdullah, Nur Sarimah Kamilia Hoo] Gleneagles Med Ctr, Jerudong, Brunei.
   [Ping, Lim Boon] Subang Jaya Med Ctr, Subang Jaya, Malaysia.
   [Nair, Harikrishna K. R.] Hosp Kuala Lumpur, Dept Internal Med, Wound Care Unit, Kuala Lumpur, Malaysia.
RP Wen, CWY (通讯作者)，Soza Healthcare Sdn Bhd, Petaling Jaya, Malaysia.
EM Claire8688@gmail.com
CR Agarwal A, 2022, J ORTHOP TRAUMA, V36, pS1, DOI 10.1097/BOT.0000000000002431
   [Anonymous], Guiding the practice of wound debridement using best practice recommendations and consensus statements
   Apelqvist Jan, 2017, J Wound Care, V26, pS1, DOI [10.12968/jowc.2017.26.sup3.s1, 10.12968/jowc.2017.26.Sup3.S1]
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Atkin L, 2019, J WOUND CARE, V28, pS5, DOI 10.12968/jowc.2019.28.Sup3a.S1
   Lee Hyun-Joo, 2009, J Orthop Surg Res, V4, P14, DOI 10.1186/1749-799X-4-14
   Malmsjo Malin, 2012, Eplasty, V12, pe5
   Medical Advisory Secretariat, 2006, Ont Health Technol Assess Ser, V6, P1
   Sulaiman AN, 2021, Trauma Cases and Reviews, V7, DOI [10.23937/2469-5777/1510087, 10.23937/2469-5777/1510087, DOI 10.23937/2469-5777/1510087]
   Nair HK, 2021, Wounds Asia, V3, P57
   Van Rysselberghe NL, 2022, J ORTHOP TRAUMA, V36, pS6, DOI 10.1097/BOT.0000000000002430
NR 11
TC 1
Z9 1
U1 0
U2 1
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD OCT
PY 2023
VL 32
SU 10A
BP S16
EP S20
DI 10.12968/jowc.2023.32.Sup10a.S16
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA U8LW9
UT WOS:001087271800003
PM 37830842
DA 2026-07-24
ER

PT J
AU Krejcí, M
   Novotny, T
   Staffa, R
   Jureníková, P
AF Krejci, M.
   Novotny, T.
   Staffa, R.
   Jurenikova, P.
TI The use of negative pressure wound therapy for wound complication
   management after vascular procedures
SO CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE
LA Czech
DT Article
DE infection; vascular surgery; negative pressure wound therapy; vascular
   surgical procedure
ID SURGICAL SITE INFECTIONS; GRAFTS
AB Aim: To evaluate the results of negative pressure wound therapy (NPWT) in the management of post-operative wound infections (Szilagyi's classification grade II and III) after elective arterial revascularization. Patients and methods: Retrospective analysis of patients' data. All patients who were treated between 2015 and 2018 using NPWT for wound infections after elective arterial procedures on lower extremities were included. Results: Between 2015 and 2018 a total of 13 patients have been treated using NPWT after elective infrainguinal arterial revascularization. There were nine men and four women of an average age of 72 years. Nine patients were treated for Szilagyi grade II infection (69.2%) and four patients for Szilagyi grade III infection (30.8%). In 11 cases there was an early postoperative infection (84.6%). The most common bacterial agent was Staphylococcus aureus. The minimum follow-up was 12 months. During the follow-up, the patency of arterial reconstructions was 92.3% and in 84.6% complete wound healing was achieved. The treatment success rate in the artificial graft patients' group was 88.9%. Conclusion: NPWT is an effective treatment of wound infections in patients after arterial lower extremity revascularization. The method shows promising results in the management of artificial graft infection as well.
C1 [Krejci, M.; Novotny, T.; Staffa, R.] MU, LF, Chirurg Klin 2, Ctr Cevnich Onemocneni, Brno, Czech Republic.
   [Krejci, M.; Novotny, T.; Staffa, R.] Sv Anny Brne, FN, Brno, Czech Republic.
   [Jurenikova, P.] MU, LF, Katedra Osetrovatelstvi & Porodni Asistence, Brno, Czech Republic.
C3 Masaryk University; St. Anne's University Hospital Brno (FNUSA); St.
   Anne's University Hospital Brno (FNUSA-ICRC); Masaryk University
RP Krejcí, M (通讯作者)，Sv Anny Brne, FN, Ctr Cevnich Onemocneni, Chirurg Klin 2, Pekarska 664-53, Brno 65691, Czech Republic.
EM miroslay.krejci@fnusa.cz
RI Novotny, Tomas/LYO-1198-2024; Krejci, Miroslav/JDW-3906-2023
CR Antalová N, 2018, CESK SLOV NEUROL N, V81, pS23, DOI 10.14735/amcsnn2018S23
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NR 17
TC 1
Z9 1
U1 1
U2 6
PU CZECH MEDICAL SOC
PI PRAGUE 2
PA SOKOLSKA 31, PRAGUE 2 120 26, CZECH REPUBLIC
SN 1210-7859
EI 1802-4041
J9 CESK SLOV NEUROL N
JI Cesk. Slov. Neurol. Neurochir.
PY 2019
VL 82
SU 1
BP S29
EP S32
DI 10.14735/amcsnn2019S29
PG 4
WC Neurosciences; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA JT4SO
UT WOS:000500981300006
DA 2026-07-24
ER

PT J
AU Pirski, MI
   Malerba, S
   Marano, L
   Kur, M
   Skokowski, J
   Swierblewski, M
AF Pirski, Maria Ignacy
   Malerba, Silvia
   Marano, Luigi
   Kur, Martyna
   Skokowski, Jaroslaw
   Swierblewski, Maciej
TI Negative Pressure Wound Therapy as a Key Strategy in the Management of
   Severe Diabetic Foot Ulcers in Septic Frail Patients: A Case Series
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE amputation; complicated diabetic foot; frail septic patients; NPWT;
   wound healing
ID UPDATE; RISK
AB Diabetes mellitus represents a major global health challenge, with over 537 million adults currently affected worldwide. Among its complications, diabetic foot ulcers remain a leading cause of morbidity, hospitalization and amputation, imposing a significant socioeconomic burden. Effective management requires a multidisciplinary approach integrating surgical, medical and rehabilitative expertise. Negative pressure wound therapy has demonstrated clinical efficacy in promoting granulation tissue formation, accelerating wound healing, and reducing infection rates compared with conventional dressings. This case series presents the management of four frail, septic patients with severe diabetic foot ulcers treated between 2023 and 2025 in an academic surgical department. All patients required surgical intervention, including debridement or partial amputation, combined with negative pressure wound therapy and, in selected cases, revascularization or skin grafting. One case utilized an electrospun nanofiber dressing which enhanced wound granulation and shortened healing time. Outcomes varied according to systemic comorbidities, vascular status and glycemic control; however, NPWT consistently supported wound stabilization and preparation for definitive closure. These findings reinforce the essential role of interdisciplinary collaboration and advanced wound technologies in the treatment of complex diabetic foot infections, particularly in frail or septic patients, and highlight the potential of nanofiber-based dressings as adjunctive therapies in comprehensive diabetic foot care.
C1 [Pirski, Maria Ignacy; Malerba, Silvia; Marano, Luigi; Kur, Martyna; Skokowski, Jaroslaw; Swierblewski, Maciej] St Wojciech Hosp, Nicolaus Copernicus Hlth Ctr, Dept Gen Surg & Surg Oncol, Gdansk, Poland.
   [Malerba, Silvia; Marano, Luigi; Skokowski, Jaroslaw] Acad Appl Med & Social Sci, Dept Med, AMiSNS Akad Medycznych I Spolecznych Nauk Stosowan, Elblag, Poland.
   [Malerba, Silvia] Univ Bari Aldo Moro, Dept Precis & Regenerat Med & Ionian Area, Bari, Italy.
   [Marano, Luigi] Dnipro State Med Univ, Dept Surg, Dnipro, Ukraine.
C3 Universita degli Studi di Bari Aldo Moro; Dnipro State Medical
   University
RP Marano, L (通讯作者)，St Wojciech Hosp, Nicolaus Copernicus Hlth Ctr, Dept Gen Surg & Surg Oncol, Gdansk, Poland.; Marano, L (通讯作者)，Acad Appl Med & Social Sci, Dept Med, AMiSNS Akad Medycznych I Spolecznych Nauk Stosowan, Elblag, Poland.; Marano, L (通讯作者)，Dnipro State Med Univ, Dept Surg, Dnipro, Ukraine.
EM l.marano@amisns.edu.pl
RI Marano, Luigi/K-4944-2013; Skokowski, Jaroslaw/C-6906-2011
CR Alder AC, 2006, AM J SURG, V192, P644, DOI 10.1016/j.amjsurg.2006.08.004
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NR 26
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR 28
PY 2026
VL 23
IS 5
AR e70926
DI 10.1111/iwj.70926
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA HE5UY
UT WOS:001752186000001
PM 42049636
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Orlov, A
   Ciliberti, M
   Somma, R
   Gefen, A
AF Orlov, Aleksei
   Ciliberti, Marino
   Somma, Rosa
   Gefen, Amit
TI A robotic venous leg ulcer system reveals the benefits of negative
   pressure wound therapy in effective fluid handling
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE bioengineering laboratory testing; chronic wounds; compression therapy;
   exudate management; superabsorbent and foam dressings
ID MANAGEMENT; CARE
AB We applied a market-leading, single-use negative pressure wound therapy device to a robotic venous leg ulcer system and compared its fluid handling performance with that of standard of care, superabsorbent and foam dressings and compression therapy. For each tested product, we determined a metrics of retained, residual, evaporated and (potential) leaked fluid shares, for three exudate flow regimes representing different possible clinically relevant scenarios. The single-use negative pressure wound therapy system under investigation emerged as the leading treatment option in the aspects of adequate fluid handling and consistent delivery of therapeutic-level wound-bed pressures. The superabsorbent dressing performed reasonably in fluid handling (resulting in some pooling but no leakage), however, it quickly caused excessive wound-bed pressures due to swelling, after less than a day of simulated use. The foam dressing exhibited the poorest fluid handling performance, that is, pooling in the wound-bed as well as occasional leakage, indicating potential inflammation and peri-wound skin maceration risks under real-world clinical use conditions. These laboratory findings highlight the importance of advanced robotic technology as contemporary means to simulate patient and wound behaviours and inform selection of wound care technologies and products, in ways that are impossible to achieve if relying solely on clinical trials and experience.
C1 [Orlov, Aleksei; Gefen, Amit] Tel Aviv Univ, Fac Engn, Dept Biomed Engn, IL-69978 Tel Aviv, Israel.
   [Ciliberti, Marino; Somma, Rosa] Ctr Aziendale Riparaz Tissutale, Wound Care Ctr, Castellammare Di Stabia, Italy.
C3 Tel Aviv University
RP Gefen, A (通讯作者)，Tel Aviv Univ, Fac Engn, Dept Biomed Engn, IL-69978 Tel Aviv, Israel.
EM gefen@tauex.tau.ac.il
RI Gefen, Amit/M-4720-2015
OI Gefen, Amit/0000-0002-0223-7218
FU This work was partially supported by the Israeli Ministry of Science and
   Technology (Medical Devices Program Grant no. 3-17421, awarded to
   Professor Amit Gefen in 2020). In addition, Smith amp;amp; Nephew
   Medical Limited (Watford, United Kingdom) provided [3-17421]; Israeli
   Ministry of Science and Technology (Medical Devices Program); Smith
   amp;amp; Nephew Medical Limited (Watford, United Kingdom)
FX This work was partially supported by the Israeli Ministry of Science and
   Technology (Medical Devices Program Grant no. 3-17421, awarded to
   Professor Amit Gefen in 2020). In addition, Smith & Nephew Medical
   Limited (Watford, United Kingdom) provided financial funding for this
   study.
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NR 44
TC 8
Z9 8
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD FEB
PY 2024
VL 21
IS 2
DI 10.1111/iwj.14426
EA OCT 2023
PG 13
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA JB7X4
UT WOS:001073711100001
PM 37786996
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Andrews, E
   Arko-Cobbah, E
   Bruwer, F
   Laher, S
   Miseer, S
   Moeng, MS
   Ngcakani, A
   Scott, D
   Vadia, S
   Trivedi, S
AF Andrews, Ethel
   Arko-cobbah, Emmanuel
   Bruwer, Febe
   Laher, Saadia
   Miseer, Sanesh
   Moeng, Maeyane S.
   Ngcakani, Anati
   Scott, Devan
   Vadia, Suleman
   Trivedi, Sadhana
TI Negative Pressure Wound Therapy With Instillation and Closed Incision
   Negative Pressure Therapy Use in South Africa: Expert Panel
   Recommendations
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE closed incision negative pressure therapy; consensus recommendations;
   negative pressure wound therapy with instillation; South Africa
ID HIGH-RISK PATIENTS; MAJOR MUSCLE FLAP; DWELL TIME; CARE; COMPLICATIONS;
   INFECTION; PREVALENCE; MANAGEMENT; DRESSINGS; STANDARD
AB The healthcare landscape in South Africa is challenging with a complex patient population and a stressed healthcare system. Negative pressure therapy-based systems such as negative pressure wound therapy with instillation and dwell (NPWTi-d) and closed incision negative pressure therapy (ciNPT) can help manage wounds or incisions. However, guidelines for South Africa-specific use are limited. An in-person meeting was held with 10 experts to develop South Africa-specific therapy use recommendations for NPWTi-d and ciNPT. Panel members recommended NPWTi-d use for wounds in need of cleansing. Normal saline and a 10-min dwell time were recommended with the caveat that the instillation solutions and dwell times can be changed based on the wound bed condition and the features of the instillation solution. A negative pressure cycle of 2-3 h and a negative pressure of -125 mmHg were also recommended for NPWTi-d. In patients, incisions, and surgical procedures at high risk of developing surgical site complications, ciNPT use was recommended. These general recommendations serve as a framework for NPWTi-d and/or ciNPT use in South Africa and should be updated as more region-specific evidence becomes available.
C1 [Andrews, Ethel] Univ Witwatersrand, Nursing Educ, Johannesburg, South Africa.
   [Arko-cobbah, Emmanuel] Mediclin Bloemfontein, Surg, Bloemfontein, South Africa.
   [Bruwer, Febe] Life Roseacres Hosp, Adv Wound Care, Germiston, South Africa.
   [Laher, Saadia] Netcare Alberton Hosp, Plast & Reconstruct Surg, Alberton, South Africa.
   [Laher, Saadia] Midvaal Hosp, Plast & Reconstruct Surg, Johannesburg, South Africa.
   [Miseer, Sanesh] Tygerberg Acad Hosp, Orthopaed, Cape Town, South Africa.
   [Moeng, Maeyane S.] Univ Witwatersrand, Trauma Surg, Johannesburg, South Africa.
   [Ngcakani, Anati] Edenvale Gen Hosp, Orthopaed, Edenvale, South Africa.
   [Scott, Devan] Life Anncron Hosp, Cardiothorac Surg, Klerksdorp, South Africa.
   [Vadia, Suleman] Netcare Milpk & Rosebank Hosp, Plast Reconstruct & Cosmet Surg, Johannesburg, South Africa.
   [Trivedi, Sadhana] Solventum, Med Surg, Dublin, Ireland.
C3 University of Witwatersrand; University of Witwatersrand
RP Trivedi, S (通讯作者)，Solventum, Med Surg, Dublin, Ireland.
EM strivedi2@solventum.com
RI MOENG, Maeyane Stephens/OPN-3614-2025; Bruwer, Febe
   Antoinette/MTC-0199-2025
OI MOENG, Maeyane Stephens/0000-0001-7459-3388; Bruwer, Febe
   Antoinette/0000-0003-0947-0159; 
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NR 69
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD NOV 16
PY 2025
VL 22
IS 11
AR e70790
DI 10.1111/iwj.70790
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 9UY2T
UT WOS:001615635400001
PM 41230876
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ben-Nakhi, M
   Albeshri, H
   Aljindan, F
   Alkhatieb, M
   Al-Malaq, A
   Al Subhi, F
   Baguneid, M
   Cherubino, M
   Mushara, SF
   Khattab, Y
   Laher, S
   Ribeiro, MAF Jr
   Vadia, S
   Trivedi, S
   Portou, MJ
AF Ben-nakhi, Muneera
   Albeshri, Heitham
   Aljindan, Fahad
   Alkhatieb, Maram
   Al-Malaq, Ali
   Al Subhi, Fatema
   Baguneid, Mohamed
   Cherubino, Mario
   Mushara, Samiah Faraj
   Khattab, Yasser
   Laher, Saadia
   Ribeiro Jr, Marcelo A. F.
   Vadia, Suleman
   Trivedi, Sadhana
   Portou, Mark J.
TI Negative Pressure Wound Therapy Use: Recommendations and Insights From a
   Middle Eastern Panel of Experts
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE algorithm; negative pressure wound therapy; patient care management;
   surgical wounds; wounds
ID DIABETIC FOOT ULCERS; BED PREPARATION; INSTILLATION; DRESSINGS; CARE
AB The number of patients requiring wound care is increasing, placing a burden on healthcare institutions and clinicians. While negative pressure wound therapy (NPWT) use has become increasingly common, Middle East-specific wound care guidelines are limited. An in-person meeting was held in Dubai with 15 wound care experts to develop guidelines for NPWT and NPWT with instillation and dwell (NPWTi-d) use for the Middle East. A literature search was performed using PubMed, Science Direct and Cochrane Reviews. Prior to the meeting, panel members reviewed literature and existing guidelines on NPWT and/or NPWTi-d use. A wound management treatment algorithm was created. Patient and wound assessment at presentation and throughout the treatment plan was recommended. Primary closure was recommended for simple wounds, and NPWT use was suggested for complex wounds requiring wound bed preparation. NPWTi-d use was advised when wound cleansing is required, if the patient is unsuitable for surgical debridement, or if surgical debridement is delayed. When NPWTi-d is unavailable, panel members recommended NPWT. Panel members recommended NPWT for wound bed preparation and NPWTi-d when wound cleansing is needed. These recommendations provide general guidance for NPWT and NPWTi-d use and should be updated as more clinical evidence becomes available.
C1 [Ben-nakhi, Muneera] Al Adan Hosp, Plast & Reconstruct Surg Unit, Ahmadi, Kuwait.
   [Albeshri, Heitham] King Faisal Specialist Hosp & Res Ctr, Vasc & Endovascular Surg, Jeddah, Saudi Arabia.
   [Aljindan, Fahad] King Fahad Med City Makkah, Plast & Reconstruct Surg, Mecca, Saudi Arabia.
   [Alkhatieb, Maram] King Abdulaziz Univ, Gen Surg Dept, Jeddah, Saudi Arabia.
   [Al-Malaq, Ali] King Faisal Specialist Hosp & Res Ctr, Plast Surg, Riyadh, Saudi Arabia.
   [Al Subhi, Fatema] Prince Sultan Mil Med City, Plast Surg & Burn Unit, Riyadh, Saudi Arabia.
   [Baguneid, Mohamed] Sheikh Shakhbout Med City, Vasc Surg, Abu Dhabi, U Arab Emirates.
   [Cherubino, Mario] Cleveland Clin, Plast Surg, Abu Dhabi, U Arab Emirates.
   [Mushara, Samiah Faraj] King Fahad Gen Hosp, Minist Hlth, Jeddah, Saudi Arabia.
   [Khattab, Yasser] Kings Coll Hosp London, Mediclin City Hosp, Plast Aesthet & Hand Surg, Dubai Healthcare City, Dubai, U Arab Emirates.
   [Laher, Saadia] Netcare Alberton Union Hosp, Plast & Reconstruct Surg, Johannesburg, South Africa.
   [Laher, Saadia] Midvaal Hosp, Johannesburg, South Africa.
   [Ribeiro Jr, Marcelo A. F.] Univ Maryland, R Adams Cowley Shock Trauma Ctr, Surg Trauma & Acute Care Surg, Baltimore, MD USA.
   [Vadia, Suleman] Netcare Milpk & Rosebank Hosp, Plast Reconstruct & Cosmet Surg, Johannesburg, South Africa.
   [Trivedi, Sadhana] Solventum, Med Surg, Dublin, Ireland.
   [Portou, Mark J.] Royal Free Hosp, Vasc Surg, London, England.
C3 Al Adan Hospital; King Faisal Specialist Hospital & Research Center;
   King Abdulaziz University; King Faisal Specialist Hospital & Research
   Center; Prince Sultan Military Medical City; Sheikh Khalifa Specialty
   Hospital; Cleveland Clinic Foundation; Ministry of Health - Saudi
   Arabia; King Fahd Hospital Jeddah; University System of Maryland;
   University of Maryland Baltimore; University of London; University
   College London; Royal Free London NHS Foundation Trust; UCL Medical
   School
RP Portou, MJ (通讯作者)，Royal Free Hosp, Vasc Surg, London, England.
EM m.portou@nhs.net
RI Alkhatieb, Maram/ABE-3378-2020; Cherubino, Mario/N-1780-2019
OI Alkhatieb, Maram/0000-0002-7060-6660; Cherubino,
   Mario/0000-0003-1196-3075
FU Solventum Corporation
FX The authors thank Julie M. Robertson, Julissa Ramos and Ricardo Martinez
   (Solventum) for assistance with manuscript preparation and editing.
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NR 44
TC 1
Z9 1
U1 1
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD NOV 27
PY 2025
VL 22
IS 12
AR e70791
DI 10.1111/iwj.70791
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA I7333
UT WOS:001626842800001
PM 41306082
OA gold
DA 2026-07-24
ER

PT J
AU Polykandriotis, E
   Horch, RE
   Jost, M
   Arkudas, A
   Kees, F
   Schmitz, M
AF Polykandriotis, Elias
   Horch, Raymund E.
   Jost, Matthias
   Arkudas, Andreas
   Kees, Frieder
   Schmitz, Marweh
TI Can systemically administered antibiotics be detected in wound tissues
   and surfaces under negative pressure wound therapy?
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE interstitial fluid; moxifloxacin; negative pressure wound therapy
   (NPWT); pharmacokinetics; wound infection
ID OBESE WOMEN; 400 MG; MOXIFLOXACIN; FLUID; PENETRATION; PHARMACOKINETICS;
   PROPHYLAXIS; MANAGEMENT; VANCOMYCIN; HEALTHY
AB In this study, we evaluated a new aspect of negative pressure wound therapy (NPWT) as an analytical tool for pharmacokinetic studies. Twenty-one patients with soft tissue defects scheduled to receive NPWT were included in this study. Concomitant to NPWT, all patients received intravenous moxifloxacin (MX). At different time intervals, blood plasma levels of MX were sampled and compared with synchronous concentrations of MX in the exudate obtained from the NPWT drainage system. Serial measurements were performed upon initiation of the therapy as well as in the steady state (after 5 days). At steady state, wound tissue was obtained intraoperatively. High-performance liquid-chromatography (HPLC) was used for analysis. At 1 hour post-administration, the exudate/plasma levels (mg/L) were 1.92/3.07; at 12 hours, 0.80/1.14; at 24 hours, 0.26/0.43; and at 120 hours (steady state), 0.42/0.47. There was a correlation between exudate and plasma levels reaching approximately 0.75. Until now, methods for pharmacokinetic studies concerning interstitial fluid are difficult to apply in the clinical context. The presented method showed limitations, but we believe that, after methodological improvements, measurements of substances in the interstitial fluid by means of NPWT are feasible.
C1 [Polykandriotis, Elias] Sana Klinikum Hof, Dept Plast Hand & Microsurg, Hof, Germany.
   [Polykandriotis, Elias; Horch, Raymund E.; Arkudas, Andreas; Schmitz, Marweh] Univ Erlangen Nurnberg, Med Ctr, Dept Plast & Hand Surg, Erlangen, Germany.
   [Jost, Matthias] Klinikum Nuernberg, Dept Internal Med 6, Gastrenterol, Endocrinol, Nurnberg, Germany.
   [Kees, Frieder] Univ Regensburg, Inst Pharmacol & Toxicol, Regensburg, Germany.
C3 University of Erlangen Nuremberg; Klinikum Nurnberg; University of
   Regensburg
RP Polykandriotis, E (通讯作者)，Alexander Univ Erlangen Nurnberg FAU, Acad Teaching Hosp Friedrich, Sana Klinikum Hof GmbH, Abt Plast Hand & Mikrochirurg, Eppenreuther Str 9, D-95032 Hof, Germany.
EM elias.polykandriotis@sana.de
RI Arkudas, Andreas/AAQ-6745-2021; Horch, Raymund/H-8128-2019
OI Arkudas, Andreas/0000-0002-2473-5816; Polykaniotis,
   Elias/0000-0002-8152-6420; 
FU Bayer Healthcare AG
FX Bayer Healthcare AG
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NR 27
TC 8
Z9 8
U1 1
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2019
VL 16
IS 2
BP 503
EP 510
DI 10.1111/iwj.13063
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA HQ7VT
UT WOS:000462632200024
PM 30604928
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Zeng, FJ
   Chen, C
   Chen, XY
   Zhang, L
   Liu, MH
AF Zeng, Fanjie
   Chen, Cong
   Chen, Xiangyu
   Zhang, Lei
   Liu, Minghua
TI Small Incisions Combined with Negative-Pressure Wound Therapy for
   Treatment of Protobothrops Mucrosquamatus Bite Envenomation: A
   New Treatment Strategy
SO MEDICAL SCIENCE MONITOR
LA English
DT Article
DE Bite Envenomation; Negative-Pressure Wound Therapy; Systemic
   Inflammatory Response Syndrome
ID LOCAL TISSUE-DAMAGE; RATTLESNAKE BITES; BOTHROPS; SNAKEBITE; ENDOCAN;
   ALPHA
AB Background: The aim of this study was to assess the effects of a new treatment strategy for envenomation that consists of multiple small incisions and negative-pressure wound therapy (NPWT) on injured limb swelling and systemic inflammatory reaction.
   Material/Methods: This was a prospective randomized controlled trial on snakebite envenomation. The enrolled patients were randomly divided into 2 groups: an observation group and a control group. The traditional comprehensive treatment was administered in both groups, but the observation group also received combined treatment with multiple small incisions and NPWT. Reduction in limb swelling, mean admission duration, complication rate, and changes in the levels of relevant cytokines were recorded and compared between the 2 groups.
   Results: The mean duration of hospital stay was significantly lower in the observation group than in the control group (5.44 +/- 0.89 days vs. 7.71 +/- 1.70 days). The complication rate and IL-6 concentration were significantly lower in the observation group than in the control group.
   Conclusions: Multiple small incisions combined with NPWT proved effective for controlling the release of inflammatory cytokines and accelerating the relief of systemic inflammatory reaction. As a consequence, the complication rate decreased. Therefore, our new treatment strategy is safe and effective.
C1 [Zeng, Fanjie; Chen, Xiangyu; Zhang, Lei; Liu, Minghua] Army Med Univ, Southwest Hosp, Emergency Dept, Chongqing, Peoples R China.
   [Zeng, Fanjie] 31631 Troop Peoples Liberation Army, Souad Hlth Clin 90, Huizhou, Guangdong, Peoples R China.
   [Chen, Cong] 187th Mil Hosp Peoples Liberat Army, Emergency Dept, Haikou, Hainan, Peoples R China.
C3 Army Medical University
RP Liu, MH (通讯作者)，Army Med Univ, Southwest Hosp, Emergency Dept, Chongqing, Peoples R China.
EM cnminghualiu@163.com
FU Chongqing Science and Technology Benefiting Project
   [CSTC2013jcsfC1001-4]; Scientific Research Innovation Fund of AMU
   [SWH2013LC11]
FX This research was funded by the Chongqing Science and Technology
   Benefiting Project (CSTC2013jcsfC1001-4) and Scientific Research
   Innovation Fund of AMU (SWH2013LC11)
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NR 21
TC 14
Z9 19
U1 1
U2 7
PU INT SCIENTIFIC INFORMATION, INC
PI MELVILLE
PA 150 BROADHOLLOW RD, STE 114, MELVILLE, NY 11747 USA
EI 1643-3750
J9 MED SCI MONITOR
JI Med. Sci. Monitor
PD JUN 17
PY 2019
VL 25
BP 4495
EP 4502
DI 10.12659/MSM.913579
PG 8
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA IE7JP
UT WOS:000472550600001
PM 31204383
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Qian, K
   Bao, WX
   Zuo, N
   Wang, S
   Ding, W
AF Qian, Kun
   Bao, Wen-Xiu
   Zuo, Na
   Wang, Shuai
   Ding, Wei
TI The synergistic effects of platelet-rich plasma and negative pressure
   wound therapy in cavitary infected wounds: a single-centre experience
SO JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
LA English
DT Article
DE Cavitary wounds; infection; negative pressure wound therapy;
   platelet-rich plasma; wound management; wound healing
ID EFFICACY; GEL; METAANALYSIS
AB Objective To evaluate the efficacy of the combined application of platelet-rich plasma (PRP) and negative pressure wound therapy (NPWT) in cavitary infected wounds, in addition to the parameter settings of NPWT.Methods The outcomes of patients with cavitary wounds who received debridement with either PRP plus NPWT (PRP group) or NPWT alone (controls) as part of their treatment protocol were retrospectively compared by examining preoperative and postoperative data on high-sensitivity C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR), white blood cell (WBC) count, neutrophil percentage, bacterial cultures, pain (measured using visual analogue scale [VAS] scores), postoperative hospitalization duration, and effective hospitalization days.Results A total of 24 patients were included (11 who received PRP plus NPWT and 13 who received NPWT alone). Postoperative hs-CRP levels, ESR, VAS scores, and effective hospitalization days were found to be significantly reduced in the PRP group versus controls. Moreover, the PRP group exhibited a significantly elevated rate of bacterial culture conversion at postoperative day 3.Conclusions The integration of surgical debridement with PRP and NPWT in the management of infected cavitary wounds may expedite infection containment and bacterial eradication, stimulate granulation tissue formation, and facilitate cavity closure, offering a novel and uncomplicated approach to wound healing.
C1 [Qian, Kun; Bao, Wen-Xiu; Wang, Shuai; Ding, Wei] First Affiliated Hosp, Wannan Med Coll, Dept Burn & Plast Surg, 2 Zhe ShanWest Rd, Wuhu 241000, Anhui, Peoples R China.
   [Zuo, Na] First Affiliated Hosp, Wannan Med Coll, Dept Otolaryngol Head & Neck Surg, Wuhu, Anhui, Peoples R China.
C3 Wannan Medical College; Wannan Medical College
RP Ding, W (通讯作者)，First Affiliated Hosp, Wannan Med Coll, Dept Burn & Plast Surg, 2 Zhe ShanWest Rd, Wuhu 241000, Anhui, Peoples R China.
EM 13956174927@163.com
OI Qian, Kun/0009-0003-9247-2901
FU Construction of Standardized Treatment System for Acute Wounds in
   Southern Anhui Province, China; Blood Transfusion Department of the
   First Affiliated Hospital of Wannan Medical College
FX The authors are grateful to the patients and their families who
   participated in this study, as well as the staff who were not at the
   centre. We thank Dr Tao Yuqi of the Blood Transfusion Department of the
   First Affiliated Hospital of Wannan Medical College for her work in
   venous blood collection.
CR Bouza E, 2022, CURR OPIN INFECT DIS, V35, P61, DOI 10.1097/QCO.0000000000000814
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   Murray IR, 2017, J BONE JOINT SURG AM, V99, P809, DOI 10.2106/JBJS.16.00793
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   Portier I, 2021, ARTERIOSCL THROM VAS, V41, P70, DOI 10.1161/ATVBAHA.120.314645
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NR 30
TC 1
Z9 1
U1 2
U2 7
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 0300-0605
EI 1473-2300
J9 J INT MED RES
JI J. Int. Med. Res.
PD NOV
PY 2024
VL 52
IS 11
AR 03000605241300064
DI 10.1177/03000605241300064
PG 13
WC Medicine, Research & Experimental; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Pharmacology & Pharmacy
GA N0R4G
UT WOS:001361502400001
PM 39579349
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Oshima, J
   Inoue, Y
   Sasaki, K
   Sekido, M
AF Oshima, Junya
   Inoue, Yoshiaki
   Sasaki, Kaoru
   Sekido, Mitsuru
TI Various Purposes of Negative Pressure Wound Therapy in Severe Burn
   Treatment: a Short Case Series Analysis
SO INDIAN JOURNAL OF SURGERY
LA English
DT Article
DE Burn; Flap surgery; Negative pressure wound therapy; Skin graft
ID SKIN-GRAFT; DONOR SITE; RECONSTRUCTION; MANAGEMENT; FLAP
AB The purposes for performing negative pressure wound therapy (NPWT) in severe burns are diverse, but few reports comprehensively discussing its indications and methods have been published. We included patients with a >= 30% total burn area. There were 4 patients, and a total of 9 NPWT were performed. The therapy sites were the upper extremity (n = 2), the elbow (n = 1), the dorsum of the hand (n = 5), and the knee (n = 1). The purposes of the therapy were bridge-to-skin grafting (n = 5), dressing the artificial dermis (n = 1), therapy for bolstering the autograft (n = 1), bridge-to-flap surgery (n = 1), and covering the flap (n = 1). The devices used were bedside wall suction (n = 5) and dedicated device (n = 3). Therapy was converted to wall aspiration after use of the dedicated device in 1 case. NPWT is an effective option in severe burn treatment. For each purpose, it is necessary to consider the device used, negative pressure setting, starting date, frequency of dressing changes, and period of therapy. NPWT in severe burns also has the advantage of prioritizing life-prolonging treatment. If strict control of negative pressure is required, a dedicated device should be used rather than wall suction.
C1 [Oshima, Junya; Sasaki, Kaoru; Sekido, Mitsuru] Univ Tsukuba, Dept Plast Reconstruct & Hand Surg, Tsukuba, Ibaraki, Japan.
   [Inoue, Yoshiaki] Univ Tsukuba, Dept Emergency & Crit Care Med, Tsukuba, Ibaraki, Japan.
C3 University of Tsukuba; University of Tsukuba
RP Oshima, J (通讯作者)，Univ Tsukuba, Dept Plast Reconstruct & Hand Surg, Tsukuba, Ibaraki, Japan.
EM ooshima-tuk@umin.ac.jp
CR Bi HD, 2018, J RECONSTR MICROSURG, V34, P200, DOI 10.1055/s-0037-1608621
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   Yin YC, 2018, INT J SURG, V50, P43, DOI 10.1016/j.ijsu.2017.12.020
NR 24
TC 0
Z9 1
U1 0
U2 2
PU SPRINGER INDIA
PI NEW DELHI
PA 7TH FLOOR, VIJAYA BUILDING, 17, BARAKHAMBA ROAD, NEW DELHI, 110 001,
   INDIA
SN 0972-2068
EI 0973-9793
J9 INDIAN J SURG
JI Indian J. Surg
PD JUN
PY 2024
VL 86
IS 3
BP 554
EP 560
DI 10.1007/s12262-023-03902-0
EA AUG 2023
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA A5G2I
UT WOS:001196181300001
DA 2026-07-24
ER

PT J
AU Klein, R
   Mathew, R
   Spangler, DJ
   Hudson, H
   Soloway, L
   Bongards, C
AF Klein, Robert
   Mathew, Rhea
   Spangler, Daniel J.
   Hudson, Hadley
   Soloway, Laura
   Bongards, Christine
TI Use of Disposable Negative Pressure Wound Therapy in 16 Podiatry Clinic
   Patients with Chronic Wounds
SO WOUND MANAGEMENT & PREVENTION
LA English
DT Article
DE diabetic foot; lower extremity; negative pressure wound therapy;
   pressure injury; wound healing
AB BACKGROUND: Disposable mechanical negative pressure wound therapy (dNPWT) can help manage lower extremity wounds in the outpatient clinic. PURPOSE: We assessed dNPWT use in 16 patients at a podiatry clinic. METHODS: Patients were treated between October 31, 2019 and December 16, 2021. All patients received dNPWT with dressing changes every 2 to 3 days. Demographics, baseline wound and subsequent wound visit data, and treatments were recorded. Wound healing outcomes were assessed. RESULTS: Average patient age was 59.6 +/- 8.9 years old. Patient comorbidities included poor nutritional status, diabetes, and hypertension. Wound types consisted of 6 diabetic foot ulcers, 9 surgical wounds, and 1 pressure injury. At baseline, the average wound age was 15.6 weeks, average area was 5.5 cm2, and average volume was 3.3 cm3. The average time from presentation to end of dNPWT was 45.5 days. In this timeframe, wounds improved in granulation tissue amount (81%), reduced in area (63%), and reduced in volume (69%). By the end of treatment, a majority of patients (88%) displayed 76% to 100% wound bed coverage with healthy granulation tissue. The remaining 12% showed <76% coverage with granulation tissue. CONCLUSIONS: In this retrospective study, 14 of 16 patients displayed improvement in wound area, volume, and granulation tissue amount during dNPWT treatment.
C1 [Klein, Robert; Mathew, Rhea; Spangler, Daniel J.] Univ South Carolina, Sch Med, Greenville, SC USA.
   [Klein, Robert] PRISMA Hlth Upstate, Greenville, SC USA.
   [Hudson, Hadley] Furman Univ, Greenville, SC USA.
   [Soloway, Laura] 3M, St Paul, MN USA.
   [Bongards, Christine] 3M Deutschland GmbH, 3M, Neuss, Germany.
   [Klein, Robert] Prisma Hlth Upstate Greenville, 200 Patewood Dr, Suite C300, Greenville, SC 29615 USA.
C3 Prisma Health; 3M; 3M
RP Klein, R (通讯作者)，Prisma Hlth Upstate Greenville, 200 Patewood Dr, Suite C300, Greenville, SC 29615 USA.
EM robklein63@gmail.com
CR Armstrong DG, 2012, WOUND REPAIR REGEN, V20, P332, DOI 10.1111/j.1524-475X.2012.00780.x
   Bradbury S, 2015, ADV WOUND CARE, V4, P346, DOI 10.1089/wound.2014.0596
   Delhougne G, 2018, OSTOMY WOUND MANAG, V64, P26
   Fong KD, 2010, WOUNDS, V22, P230
   Fout B, 2022, ADV SKIN WOUND CARE, V35, P37, DOI 10.1097/01.ASW.0000801536.61163.e5
   Klein RJ, 2021, WOUNDS, V33, pE75, DOI 10.25270/wnds/2021.e7578
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   Sen CK, 2019, ADV WOUND CARE, V8, P39, DOI 10.1089/wound.2019.0946
   Swoboda Laura, 2021, Wounds, V33, pE85, DOI 10.25270/wnds/2021.e85e89
   Tettelbach W, 2019, WOUNDS
NR 12
TC 0
Z9 0
U1 2
U2 7
PU HMP
PI MALVERN
PA 70 E SWEDESFORD RD, STE 100, MALVERN, PA 19355 USA
SN 2640-5237
EI 2640-5245
J9 WOUND MANAG PREV
JI Wound Manag. Prev.
PD MAY
PY 2023
VL 69
IS 2
BP 26
EP 31
DI 10.25270/wmp.2023.2.22087
PG 6
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA J4YQ1
UT WOS:001009693300003
PM 37253701
DA 2026-07-24
ER

PT J
AU Okuya, K
   Takemasa, I
   Tsuruma, T
   Noda, A
   Sasaki, K
   Ueki, T
   Mukaiya, M
   Saito, K
   Okita, K
   Nishidate, T
   Akizuki, E
   Hamabe, A
   Ishii, M
AF Okuya, Koichi
   Takemasa, Ichiro
   Tsuruma, Tetsuhiro
   Noda, Ai
   Sasaki, Kenichi
   Ueki, Tomomi
   Mukaiya, Mitsuhiro
   Saito, Keita
   Okita, Kenji
   Nishidate, Toshihiko
   Akizuki, Emi
   Hamabe, Atsushi
   Ishii, Masayuki
TI Evaluation of negative-pressure wound therapy for surgical site
   infections after ileostomy closure in colorectal cancer patients: a
   prospective multicenter study
SO SURGERY TODAY
LA English
DT Article
DE Surgical site infection; Ileostomy closure; Negative-pressure wound
   therapy
ID RANDOMIZED CLINICAL-TRIAL; LOOP ILEOSTOMY; SKIN CLOSURE; OPEN-LABEL;
   RISK; MORBIDITY; SURGERY; REVERSAL; PREVENTION; OUTCOMES
AB Purpose Surgical site infection (SSI) occurs at a high rate after ileostomy closure. The effect of preventive negative-pressure wound therapy (NPWT) on SSI development in closed wounds remains controversial. We conducted a prospective multicenter study to evaluate the usefulness of preventive NPWT for SSI after ileostomy closure.
   Methods From January 2018 to November 2018, 50 patients who underwent closure of ileostomy created after surgery for colorectal cancer participated in this study. An NPWT device was applied to each wound immediately after surgery and then treatment was continued for 3 days. The primary endpoint was 30-day SSI, and the secondary endpoints were the incidence of seroma, hematoma, and adverse events related to NPWT.
   Results No patients developed SSI, seroma, or hematoma. Adverse events that may have been causally linked with NPWT were contact dermatitis in two patients and wound pain in one patient, and there were no cases of discontinuation or decompression of NPWT.
   Conclusion The use of NPWT following ileostomy closure may be useful for reducing the development of SSI in colorectal cancer patients. This is a prospective multicenter pilot study and we are planning a comparative study based on these successful results.
C1 [Okuya, Koichi; Takemasa, Ichiro; Okita, Kenji; Nishidate, Toshihiko; Akizuki, Emi; Hamabe, Atsushi; Ishii, Masayuki] Sapporo Med Univ, Dept Surg Surg Oncol & Sci, Chuo Ku, S1,W16, Sapporo, Hokkaido 0608543, Japan.
   [Tsuruma, Tetsuhiro; Ueki, Tomomi] JR Sapporo Hosp, Dept Surg, Chuo Ku, N3,E1, Sapporo, Hokkaido 0600033, Japan.
   [Noda, Ai; Ueki, Tomomi; Mukaiya, Mitsuhiro] Otaru Ekisaikai Hosp, Dept Surg, 1-4-1 Inaho, Otaru, Hokkaido 0470032, Japan.
   [Sasaki, Kenichi; Saito, Keita] Muroran City Gen Hosp, Dept Surg, 3-8-1 Yamate Cho, Muroran, Hokkaido 0518512, Japan.
C3 Sapporo Medical University
RP Takemasa, I (通讯作者)，Sapporo Med Univ, Dept Surg Surg Oncol & Sci, Chuo Ku, S1,W16, Sapporo, Hokkaido 0608543, Japan.
EM itakemasa@sapmed.ac.jp
RI Nishidate, Toshihiko/AFP-4588-2022
FU Sapporo Medical University
FX This research was carried out using research funds from the Sapporo
   Medical University. There was no financial support from any companies.
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NR 29
TC 10
Z9 10
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0941-1291
EI 1436-2813
J9 SURG TODAY
JI Surg. Today
PD DEC
PY 2020
VL 50
IS 12
BP 1687
EP 1693
DI 10.1007/s00595-020-02068-6
EA JUL 2020
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA OT7EC
UT WOS:000546767500002
PM 32638132
DA 2026-07-24
ER

PT J
AU O'Neill, CH
   Martin, RCG 
AF O'Neill, Conor H.
   Martin, Robert C. G., II
TI Negative-pressure wound therapy does not reduce superficial SSI in
   pancreatectomy and hepatectomy procedures
SO JOURNAL OF SURGICAL ONCOLOGY
LA English
DT Article
DE HPB surgery; negative pressure wound therapy; SSI; surgical site
   infection
ID SURGICAL SITE INFECTION; CARE-ASSOCIATED INFECTIONS; IMPROVEMENT
   PROJECTS; PREVENTION; GUIDELINE; HOSPITALS; OUTCOMES; IMPACT; COSTS;
   RISK
AB Introduction Surgical site infections (SSIs) lead to increased morbidity and cost. Negative-pressure wound therapy (NPWT) removes wound exudate and improves local blood flow, but its effect on SSI is unproven following hepatectomy and pancreatectomy. The aim of this trial was to evaluate the effect of NPWT on SSI in this population.
   Methods Patients were randomized to incisional NPWT or sterile island dressing following surgery. SSI predictive factors were recorded as well as patient comorbidities. Wound complications and type of SSI were recorded prospectively.
   Results Forty patients received the standardized perioperative bundle. Twenty patients received sterile island: 11 hepatic and 9 pancreatic resections; 20 patients received NPWT: 11 hepatic and 9 pancreatic resections; 23 patients were male; mean age 60.8 years (SD +/- 10.3); mean BMI 31.7 (SD +/- 7.0). There were three incisional wound infections: two with sterile island, one with NPWT; six organ space infections: four sterile island and two NPWT. There were no significant differences in SSI rates between groups (P = .57).
   Conclusion NPWT does not improve SSI rates over simple sterile dressing following hepatectomy or pancreatectomy. Improvements in SSI must be directed toward organ-space infections, which are unaffected by NPWT.
C1 [O'Neill, Conor H.; Martin, Robert C. G., II] Univ Louisville, Hiram Polk Jr MD Dept Surg, Div Surg Oncol, Louisville, KY 40292 USA.
C3 University of Louisville
RP Martin, RCG  (通讯作者)，Upper Gastrointestinal & Hepatopancreaticobiliary, 315 E Broadway 311, Louisville, KY 40202 USA.
CR Anderson DJ, 2013, AM J INFECT CONTROL, V41, P764, DOI 10.1016/j.ajic.2012.11.022
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NR 25
TC 14
Z9 16
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0022-4790
EI 1096-9098
J9 J SURG ONCOL
JI J. Surg. Oncol.
PD SEP
PY 2020
VL 122
IS 3
BP 480
EP 486
DI 10.1002/jso.25980
EA JUN 2020
PG 7
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA MS1PJ
UT WOS:000538282500001
PM 32506498
DA 2026-07-24
ER

PT J
AU Bohn, G
AF Bohn, Gregory
TI Mechanically Powered Ambulatory Negative Pressure Wound Therapy Device
   for Treatment of a Colostomy Takedown Site
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE colostomy; infected wounds; negative pressure wound therapy; ostomy;
   stoma
AB BACKGROUND: The management of postostomy takedown surgical wound sites can be challenging. Complications from these contaminated wounds can lead to serious complications such as hernia formation and increased healthcare costs. Negative pressure wound therapy (NPWT) has been shown to be potentially helpful in managing these heavily colonized wound sites. We report the case of a mechanically powered ambulatory NPWT device (SNaP Wound Care System; Spiracur Inc, Sunnyvale, California) for treating these postcolostomy takedown wounds.
   CASE: A young 9-year-old boy in Port-Au-Prince, Haiti, had under gone colostomy as a protective measure after pelvic fracture 5 months prior. Having healed the pelvic fracture and being fully ambulatory, he underwent takedown of his colostomy with reanastomosis of the bowel. At the completion of surgery, the ostomy wound site was managed by a mechanically powered NPWT device. This allowed the patient to remain ambulatory without the need for attachment to a heavier electrically powered NPWT device during healing. Dressing changes were limited to twice weekly instead of 3 times daily.
   CONCLUSION: This case demonstrates the feasibility of an underdescribed application for a new mechanically powered ambulatory negative pressure device. Findings from this case study suggest that this device may be clinically applicable for patients undergoing ostomy takedown in the United States and in developing nations such as Haiti.
C1 [Bohn, Gregory] Trinity Wound Care & Hyperbar Med, Bettendorf, IA USA.
RP Bohn, G (通讯作者)，4500 Utica Ridge Rd, Bettendorf, IA 52722 USA.
EM gregbohn1@mchsi.com
CR Armstrong DG, 2011, WOUND REPAIR REGEN, V19, P173, DOI 10.1111/j.1524-475X.2010.00658.x
   Gabriel A, 2006, WOUNDS, V18, P245
   Gabriel A, 2009, INT WOUND J, V6, P1, DOI 10.1111/j.1742-481X.2009.00628.x
   Kaiser AM, 2008, J GASTROINTEST SURG, V12, P437, DOI 10.1007/s11605-007-0457-8
   Lerman B, 2010, PLAST RECONSTR SURG, V126, P1253, DOI 10.1097/PRS.0b013e3181ea4559
   Lerman Bruce, 2010, J Diabetes Sci Technol, V4, P825
   Murray BW, 2010, J AM COLL SURGEONS, V211, P812, DOI 10.1016/j.jamcollsurg.2010.07.025
   Rosen MJ, 2006, J GASTROINTEST SURG, V10, P895, DOI 10.1016/j.gassur.2005.11.008
NR 8
TC 4
Z9 4
U1 0
U2 12
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1071-5754
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD MAY-JUN
PY 2013
VL 40
IS 3
BP 315
EP 317
DI 10.1097/WON.0b013e31828f478e
PG 3
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 142GV
UT WOS:000318786300014
PM 23652704
DA 2026-07-24
ER

PT J
AU Tseng, YL
   Wu, HS
   Huang, PY
   Hsaio, PS
   Tseng, HC
AF Tseng, Yi-Ling
   Wu, Hua-Shan
   Huang, Pei-Yu
   Hsaio, Pei-Shan
   Tseng, Hui-Chen
TI Effects of a Situated Simulation Teaching Strategy on Knowledge of
   Negative-Pressure Wound Therapy among Surgical Nurses in Taiwan
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Article
DE education; educational training; knowledge; negative-pressure wound
   therapy; situated simulation teaching; surgical nurse; wound care
ID RISK-FACTORS; EDUCATION; COMPLICATIONS; REFLECTION; OUTCOMES
AB OBJECTIVE: To evaluate the effect of a situated simulation teaching strategy for negative-pressure wound therapy (NPWT) on surgical nurses' knowledge of care for patients who receive NPWT. METHODS: This quasi-experimental study used a one-group pretest/posttest design. Thirty-one female surgical nurses from a central Taiwan district hospital participated. They received situational simulation training and completed self-administered preintervention and postintervention scale assessing their knowledge of NPWT-related care and a demographic questionnaire RESULTS: Participants' mean score on the knowledge of NPWT-related care scale was 19.90 preintervention and increased to 27.84 postintervention, a significant improvement (z = -4.45, P < .001). All aspects of NPWT knowledge, including indications and effects (z = -3.84, P < .001), device operation (z = -3.71, P < .001), assessment (z = -3.89, P < .001), and anomaly response (z = -3.93, P < .001), significantly improved following the intervention. CONCLUSIONS: The study indicates that simulation and cues and a debriefing session in situational simulation teaching significantly enhance surgical nurses' knowledge of NPWT-related care and facilitates the acquisition of problem-solving methods, suggesting its potential application in NPWT-related continuing education courses for surgical nurses.
C1 [Tseng, Yi-Ling] Tunghai Univ, Coll Agr & Hlth, Bachelor Sci Sr Wellness & Sports Sci, Taichung, Taichung County, Taiwan.
   [Wu, Hua-Shan] Asia Univ, Dept Nursing, Taichung, Taichung County, Taiwan.
   [Huang, Pei-Yu] Jen Ai Hosp, Dementia Ctr, Taichung, Taiwan.
   [Hsaio, Pei-Shan] Asia Univ Hosp, Taichung, Taiwan.
   [Tseng, Hui-Chen] Kaohsiung Med Univ, Coll Nursing, Kaohsiung, Taiwan.
   [Tseng, Hui-Chen] Kaohsiung Med Univ Hosp, Dept Med Res, Kaohsiung, Taiwan.
C3 Tunghai University; Asia University Taiwan; Kaohsiung Medical
   University; Kaohsiung Medical University; Kaohsiung Medical University
   Hospital
RP Tseng, YL (通讯作者)，Tunghai Univ, Coll Agr & Hlth, Bachelor Sci Sr Wellness & Sports Sci, Taichung, Taichung County, Taiwan.
EM elin627@yahoo.com.tw; huashan64@gmail.com; aegis22303@gmail.com;
   scorpio821031@gmail.com; huchts@kmu.edu.tw
RI ; Tseng, Hui-Chen/ABD-4738-2021
OI Tseng, Yi-Ling/0000-0002-2926-7177; Tseng, Hui-Chen/0000-0001-9621-7316
CR AL Sabei SD, 2016, NURS EDUC TODAY, V45, P42, DOI 10.1016/j.nedt.2016.06.008
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NR 41
TC 1
Z9 1
U1 3
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD JUL
PY 2025
VL 38
IS 6
BP 303
EP 309
DI 10.1097/ASW.0000000000000293
PG 7
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA 3YX6K
UT WOS:001512320900002
PM 40184506
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Chiu, HS
   Huang, TS
   Chen, CT
   Lin, XY
   Liao, PC
   Liou, CC
   Hsu, CC
   Somvanshi, S
   Sumazin, P
   Hsu, PH
   Sun, CC
   Shyu, YC
AF Chiu, Hua-Sheng
   Huang, Ting-Shuo
   Chen, Chien-Tzung
   Lin, Xin-Yu
   Liao, Po-Cheng
   Liou, Cai-Cin
   Hsu, Chih-Chin
   Somvanshi, Sonal
   Sumazin, Pavel
   Hsu, Pang-Hung
   Sun, Chi-Chin
   Shyu, Yu-Chiau
TI Temporal Regulation of Early-Stage Cytokine Expression in Diabetic Wound
   Healing Under Negative Pressure Wound Therapy
SO INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
LA English
DT Article
DE negative pressure wound therapy (NPWT); diabetic (DB); wound healing;
   cytokine profiling
ID ENDOTHELIAL GROWTH-FACTOR; FOOT ULCERS; PDGF; METAANALYSIS; FIBROBLASTS;
   BIOLOGY
AB Negative pressure wound therapy (NPWT) is widely recognized for its efficacy in treating diabetic wounds, but the mechanisms involved in the wound healing process remain unclear. By examining changes in blood cytokine levels as molecular signaling precursors, we aim to provide a comprehensive cytokine profile to support adjunctive therapy research and clinical applications. A diabetic mouse wound model was established to compare cytokine profiles between NPWT-treated and standard dressing groups, identifying key signaling candidates that may facilitate wound healing. By integrating normal mouse data with large-scale cytokine analysis, we developed a time-stratified NPWT approach to track acute-phase cytokine fluctuations in diabetic conditions. NPWT did not significantly enhance coagulation-related cytokine expression but effectively reduced inflammation, albeit with a delayed regulatory effect compared to wild-type mice. A one-sided binomial test revealed that NPWT advanced the cytokine expression peak from 16 to 2 h, partially restoring the early healing pattern seen in normal mice and suggesting its potential role in modulating early-stage wound repair. These findings provide novel insights into early cytokine regulation during wound healing and highlight the potential of NPWT to inform therapeutic strategies. This refined monitoring approach may contribute to improved clinical decision-making and support enhanced wound management in diabetic patients.
C1 [Chiu, Hua-Sheng; Somvanshi, Sonal; Sumazin, Pavel] Baylor Coll Med, Dept Pediat, Texas Childrens Canc Ctr, Houston, TX 77030 USA.
   [Huang, Ting-Shuo] Jen Ai Hosp, Dept Gen Surg, Taichung 400, Taiwan.
   [Huang, Ting-Shuo] Chang Gung Univ, Coll Med, Sch Tradit Chinese Med, Taoyuan 333, Taiwan.
   [Chen, Chien-Tzung] Chang Gung Mem Hosp, Dept Plast & Reconstruct Surg, Taoyuan 333, Taiwan.
   [Chen, Chien-Tzung] Chang Gung Univ, Craniofacial Res Ctr, Taoyuan 333, Taiwan.
   [Lin, Xin-Yu; Liao, Po-Cheng; Liou, Cai-Cin; Shyu, Yu-Chiau] Chang Gung Mem Hosp, Community Med Res Ctr, Keelung Branch, Keelung 204, Taiwan.
   [Hsu, Chih-Chin; Sun, Chi-Chin] Chang Gung Univ, Coll Med, Sch Med, Taoyuan 333, Taiwan.
   [Hsu, Chih-Chin] Chang Gung Mem Hosp, Dept Phys Med & Rehabil, Keelung Branch, Keelung 204, Taiwan.
   [Hsu, Pang-Hung] Natl Taiwan Ocean Univ, Dept Biosci & Biotechnol, Keelung 202, Taiwan.
   [Sun, Chi-Chin] Chang Gung Mem Hosp, Dept Ophthalmol, Keelung Branch, Keelung 204, Taiwan.
   [Shyu, Yu-Chiau] Chang Gung Univ Sci & Technol, Dept Nursing, Taoyuan 333, Taiwan.
C3 Texas Children's Cancer Center; Baylor College of Medicine; Chang Gung
   University; Chang Gung Memorial Hospital; Chang Gung University; Chang
   Gung Memorial Hospital; Chang Gung University; Chang Gung Memorial
   Hospital; National Taiwan Ocean University; Chang Gung Memorial
   Hospital; Chang Gung University of Science & Technology
RP Shyu, YC (通讯作者)，Chang Gung Mem Hosp, Community Med Res Ctr, Keelung Branch, Keelung 204, Taiwan.; Shyu, YC (通讯作者)，Chang Gung Univ Sci & Technol, Dept Nursing, Taoyuan 333, Taiwan.
EM hua-sheng.chiu@bcm.edu; huangts1234@gmail.com; ctchenap@cgmh.org.tw;
   love20070810@gmail.com; henryshome@gmail.com; nice302a@gmail.com;
   steele0618@gmail.com; sonal.somvanshi@bcm.edu; pavel.sumazin@bcm.edu;
   phsu@ntou.edu.tw; chichinsun@gmail.com; yuchiaushyu@gmail.com
RI Sumazin, Pavel/AAE-6607-2020; Chiu, Hua-Sheng/I-7150-2019; Hsu,
   Pang-Hung/C-5587-2018; Huang, Ting-Shuo/ABD-3205-2021
OI Sumazin, Pavel/0000-0002-1215-4977; Shyu, Yu-Chiau/0000-0003-1747-2226;
   Hsu, Chih-Chin/0000-0002-5558-3456; Lin, Xin-Yu/0000-0003-3311-1754;
   Chiu, Hua-Sheng/0000-0002-0296-5653; Hsu, Pang-Hung/0000-0001-6873-6434;
   
FU the Chang Gung Memorial Hospital Research Projects [CMRPG2L0311]; Chang
   Gung Memorial Hospital Research Projects
FX This work was supported by the Chang Gung Memorial Hospital Research
   Projects CMRPG2L0311.
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NR 43
TC 1
Z9 1
U1 1
U2 2
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
SN 1661-6596
EI 1422-0067
J9 INT J MOL SCI
JI Int. J. Mol. Sci.
PD MAY 13
PY 2025
VL 26
IS 10
AR 4634
DI 10.3390/ijms26104634
PG 15
WC Biochemistry & Molecular Biology; Chemistry, Multidisciplinary
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biochemistry & Molecular Biology; Chemistry
GA 3BQ1Y
UT WOS:001496472500001
PM 40429778
OA Green Submitted, gold
DA 2026-07-24
ER

EF