﻿FN Clarivate Analytics Web of Science
VR 1.0
PT J
AU Vidiscák, M
   Hajská, M
   Panyko, A
   Peter, Z
   Dubovsky, M
AF Vidiscak, Marian
   Hajska, Marianna
   Panyko, Arpad
   Peter, Zahorec
   Dubovsky, Martin
TI How to Prevent Surgical Site Infection of Laparotomy Incisions Using
   Negative Pressure Wound Therapy
SO BRATISLAVA MEDICAL JOURNAL
LA English
DT Article
DE Negative pressure; Complication prevention; Laparotomy incision
AB BackgroundSurgical site infection (SSI) after laparotomy remains a major source of morbidity and cost. Closed-incision negative pressure wound therapy (ciNPWT) has been proposed to prevent wound complications in high-risk patients, yet real-world evidence from abdominal surgery remains heterogeneous. We report our first experience with SSI prevention using ciNPWT in open abdominal surgery.MethodsWe conducted a retrospective clinical study of adult patients undergoing laparotomy who received ciNPWT (Prevena (TM); continuous - 125 mmHg) applied within 24 h post-closure and maintained for 6 days. The primary outcome was uncomplicated primary intention healing through suture removal (prevention "success"). Demographics, comorbidities (including diabetes, obesity, cardiovascular disease), inflammatory markers, and glycemia were collected. Logistic regression explored associations between failure and comorbidity burden. The ciNPWT group was compared with a control group of 20 patients who did not receive ciNPWT after laparotomy.ResultsTwenty patients received a single ciNPWT cycle; overall prevention success was 80%. Failure occurred in 20%. Sex and admission type were not significantly associated with outcome; median age was 69 years in successes versus 75.5 years in failures (p = 0.155). No individual comorbidity showed a significant association with failure after multiplicity adjustment. Each additional comorbidity showed a non-significant trend toward lower failure odds (OR 0.45, 95% CI 0.16-1.27; p = 0.13). Uncomplicated wound healing was achieved in 80% (16/20) of patients treated with ciNPWT compared with 45% (9/20) in the control group. (Fisher's exact test, p = 0.048; OR = 4.89), indicating borderline statistical significance.ConclusionsStandardized ciNPWT after laparotomy was feasible and associated with higher uncomplicated healing rates. Despite borderline statistical significance, the findings support the potential benefit of ciNPWT and justify further controlled studies.
C1 [Vidiscak, Marian; Hajska, Marianna; Panyko, Arpad; Dubovsky, Martin] Comenius Univ, Fac Med, Dept Surg 4, Bratislava, Slovakia.
   [Peter, Zahorec] Comenius Univ, Fac Med, Dept Burns & Reconstruct Surg, Bratislava, Slovakia.
C3 Comenius University Bratislava; Comenius University Bratislava
RP Hajská, M (通讯作者)，Comenius Univ, Fac Med, Dept Surg 4, Bratislava, Slovakia.
EM marianna.hajska@fmed.uniba.sk
RI Panyko, Arpád/AAQ-6309-2020; Vidiscak, Marian/AAZ-6765-2021
OI Panyko, Arpád/0000-0002-1895-1790; Hajská, Marianna/0000-0002-0822-8929;
   
FU Comenius University in Bratislava
FX Open access funding provided by The Ministry of Education, Science,
   Research and Sport of the Slovak Republic in cooperation with Centre for
   Scientific and Technical Information of the Slovak Republic
CR Balla VR., 2022, J SURG RES, V276, P45
   Bonds AM, 2013, DIS COLON RECTUM, V56, P1403, DOI 10.1097/DCR.0b013e3182a39959
   Cochrane Wounds Group, 2020, COCHRANE DB SYST REV, V7, DOI 10.1002/14651858.CD013308.pub2
   Daryapeyma A, 2025, BJS OPEN, V9, DOI 10.1093/bjsopen/zraf059
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   Feier CVI, 2025, J CLIN MED, V14, DOI 10.3390/jcm14155191
   Fowler A., 2018, CLIN SURG, V3, P1
   Gefen A, 2024, INT WOUND J, V21, DOI [10.1111/iwj.70098, 10.1111/iwj.70098]
   Gupta R., 2021, INT WOUND J, V18, P623
   He S, 2025, PLOS ONE, V20, DOI 10.1371/journal.pone.0328771
   Herczeg A, 2025, INT WOUND J, V22, DOI 10.1111/iwj.70718
   Hyldig N., 2019, ANN SURG, V270, P23
   Javed M., 2022, SURG INFECT LARCHMT, V23, P362
   Lynam S, 2016, INT J GYNECOL CANCER, V26, P1525, DOI 10.1097/IGC.0000000000000792
   Malmsjo Malin, 2014, Eplasty, V14, pe15
   Polomska K, 2025, INT WOUND J, V22, DOI [10.1111/iwj.70199, 10.1111/iwj.70199]
   Sahebally SM, 2018, JAMA SURG, V153, DOI 10.1001/jamasurg.2018.3467
   Wick EC, 2009, DIS COLON RECTUM, V52, P374, DOI 10.1007/DCR.0b013e31819a5e45
   Wilkes RP., 2021, INT J SURG, V84, P194
   Wong DJ., 2020, WOUND REPAIR REGEN, V28, P657
NR 20
TC 0
Z9 0
U1 2
U2 2
PU SPRINGERNATURE
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON, N1 9XW, ENGLAND
SN 0006-9248
EI 1336-0345
J9 BRATISL MED J
JI Bratisl. Med. J.
PD APR
PY 2026
VL 127
IS 4
BP 1707
EP 1712
DI 10.1007/s44411-026-00566-6
EA MAR 2026
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA FL4ON
UT WOS:001711250800001
OA gold
DA 2026-07-24
ER

PT J
AU Roman, M
   Nizamoglu, MA
   Biosse-Duplan, G
   Gearon, D
   Abood, A
   Anderson, K
AF Roman, Manuela
   Nizamoglu, Metin Ali
   Biosse-Duplan, Garance
   Gearon, Dan
   Abood, Ahid
   Anderson, Keith
TI Open lower limb fracture reconstruction in the elderly population: the
   experience of a major trauma centre
SO EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
LA English
DT Review
DE Lower limb trauma; Elderly population; BOAST 4 guidelines;
   Reconstruction
ID FREE-TISSUE TRANSFER; MANAGEMENT; INFECTION; AUDIT
AB Purpose Management of the elderly patients presenting with open lower limb fractures is challenging due to physiological changes and pre-existing co-morbidities. The aim of this study was to assess the compliance with the British Orthopaedic Association's Standards for Trauma Number 4 (BOAST 4) guidelines in this patient group. Methods The study included a retrospective analysis of all the patients aged > 65 years old admitted with open lower limb fracture between 2017 and 2019 to a major trauma centre (MTC) in East of England. Results Our study included 91 patients presenting with lower limb trauma. The most common injury was a Gustilo and Anderson grade IIIB (39.6%). 30.8% of the study population received antibiotics within 1 h, 89% had debridement and bone stabilization within 24 h. Mean time to definitive soft tissue coverage was 3 days, with 66% of the study group having their fracture fixed and soft tissue coverage within 72 h. 52% had direct wound closure, with 9% having an incisional topical negative pressure wound therapy, 17% had a local flap and 5% patients had a free flap. The most common complication was wound dehiscence. The wounds closed without an incisional topical negative pressure wound therapy have shown a dehiscence rate of 15.4%, compared to 0% in the patients who had one. Conclusion Our study suggests that BOAST 4 compliance in the population > 65 years is comparable to the younger population. It is likely that the lower energy injury profile enables early definitive management even in the presence of age related co-morbidities.
C1 [Roman, Manuela; Nizamoglu, Metin Ali; Biosse-Duplan, Garance; Gearon, Dan; Abood, Ahid; Anderson, Keith] Addenbrookes Hosp, Dept Plast & Reconstruct Surg, Hills Rd, Cambridge CB2 0QQ, England.
C3 Cambridge University Hospitals NHS Foundation Trust; Addenbrooke's
   Hospital; University of Cambridge
RP Roman, M (通讯作者)，Addenbrookes Hosp, Dept Plast & Reconstruct Surg, Hills Rd, Cambridge CB2 0QQ, England.
EM Manuela.Roman@nhs.net
CR Aloraibi S, 2021, AGE AGEING, V50, P1129, DOI 10.1093/ageing/afab071
   [Anonymous], 2016, Major trauma: service delivery
   [Anonymous], 2011, NHS services for falls and fractures in older people are inadequate, finds national clinical audit
   Beeharry MW, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.12000
   Claireaux HA, 2021, INJURY, V52, P1374, DOI 10.1016/j.injury.2020.12.038
   Coskunfirat OK, 2005, PLAST RECONSTR SURG, V115, P771, DOI 10.1097/01.PRS.0000152424.91250.A5
   Eardley W, 2020, INJURY, V51, P174, DOI 10.1016/j.injury.2019.12.034
   Kaye JA, 2004, INJURY PREV, V10, P368, DOI 10.1136/ip.2004.005843
   Khadim MF, 2019, INJURY, V50, P1376, DOI 10.1016/j.injury.2019.05.001
   Lack WD, 2015, J ORTHOP TRAUMA, V29, P1, DOI [10.1097/bot.0000000000000262, 10.1097/BOT.0000000000000262, 10.1016/j.mporth.2014.12.008]
   Lee A, 2022, JPRAS OPEN, V31, P1, DOI 10.1016/j.jpra.2021.09.003
   London Major Trauma System, Management of elderly major trauma patients
   Mathews JA, 2015, INJURY, V46, P2263, DOI 10.1016/j.injury.2015.08.027
   McCullough AL, 2014, BRIT J ANAESTH, V113, P202, DOI 10.1093/bja/aeu204
   Noblet TM, 2018, INJURY, V49, P1197, DOI 10.1016/j.injury.2018.03.010
   Rymer B, 2017, INJURY, V48, P2266, DOI 10.1016/j.injury.2017.07.012
   Serletti JM, 2000, PLAST RECONSTR SURG, V106, P66, DOI 10.1097/00006534-200007000-00012
   Weber D, 2014, J ORTHOP TRAUMA, V28, P613, DOI 10.1097/BOT.0000000000000197
   Wettstein R, 2008, J PLAST RECONSTR AES, V61, P772, DOI 10.1016/j.bjps.2007.11.037
   Yarrow J, 2015, ANN ROY COLL SURG, V97, P35, DOI 10.1308/003588414X14055925058472
   Young K, 2019, INJURY, V50, P497, DOI 10.1016/j.injury.2018.10.028
NR 21
TC 0
Z9 0
U1 0
U2 1
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 1863-9933
EI 1863-9941
J9 EUR J TRAUMA EMERG S
JI Eur. J. Trauma Emerg. Surg.
PD DEC
PY 2025
VL 51
IS 1
AR 20
DI 10.1007/s00068-024-02688-4
PG 7
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA S4P0C
UT WOS:001398048600002
PM 39815042
DA 2026-07-24
ER

PT J
AU Heo, Y
   Kim, DH
AF Heo, Yoonjung
   Kim, Dong Hun
TI The temporary abdominal closure techniques used for trauma patients: a
   systematic review and meta-analysis
SO ANNALS OF SURGICAL TREATMENT AND RESEARCH
LA English
DT Review
DE Abdominal injuries; Laparotomy; Negative-pressure wound therapy; Open
   abdomen techniques; Wound and injuries
ID DAMAGE-CONTROL LAPAROTOMY; ASSISTED FASCIAL CLOSURE; OPEN ABDOMEN; WOUND
   CLOSURE; PERITONEAL RESUSCITATION; ABBREVIATED LAPAROTOMY; COMPARTMENT
   SYNDROME; VENTRAL HERNIA; WALL CLOSURE; MANAGEMENT
AB Purpose: The choice of temporary abdominal closure (TAC) method affects the prognosis of trauma patients. Previous studies on TAC are challenging to extrapolate due to data heterogeneity. We aimed to conduct a systematic review and comparison of various TAC techniques. Methods: We accessed web-based databases for studies on the clinical outcomes of TAC techniques. Recognized techniques, including negative-pressure wound therapy with or without continuous fascial traction, skin tension, meshes, Bogota bags, and Wittman patches, were classified via a method of closure such as skin-only closure vs. patch closure vs. vacuum closure; and via dynamics of treatment like static therapy (ST) vs. dynamic therapy (DT). Study endpoints included in-hospital mortality, definitive fascial closure (DFC) rate, and incidence of intraabdominal complications. Results: Among 1,065 identified studies, 37 papers comprising 2,582 trauma patients met the inclusion criteria. The vacuum closure group showed the lowest mortality (13%; 95% confidence interval [CI], 6%-19%) and a moderate DFC rate (74%; 95% CI, 67%-82%). The skin-only closure group showed the highest mortality (35%; 95% CI, 7%-63%) and the highest DFC rate (96%; 95% CI, 93%-99%). In the second group analysis, DT showed better outcomes than ST for all endpoints. Conclusion: Vacuum closure was favorable in terms of in-hospital mortality, ventral hernia, and peritoneal abscess. Skinonly closure might be an alternative TAC method in carefully selected groups. DT may provide the best results; however, further studies are needed.
C1 [Heo, Yoonjung] Dankook Univ, Grad Sch, Dept Med, Cheonan, South Korea.
   [Heo, Yoonjung] Dankook Univ Hosp, Trauma Ctr, Dept Trauma Surg, Cheonan, South Korea.
   [Kim, Dong Hun] Dankook Univ, Coll Med, Dept Surg, Div Trauma Surg, Cheonan, South Korea.
   [Kim, Dong Hun] Dankook Univ, Coll Med, Dept Surg, Div Trauma Surg, 119 Dandae Ro, Cheonan 31116, South Korea.
C3 Dankook University; Dankook University; Dankook University Hospital;
   Dankook University; Dankook University
RP Kim, DH (通讯作者)，Dankook Univ, Coll Med, Dept Surg, Div Trauma Surg, 119 Dandae Ro, Cheonan 31116, South Korea.
EM saint7331@gmail.com
RI Heo, Yoonjung/JMQ-4158-2023
OI Heo, Yoonjung/0000-0002-8840-1794
FU  [2020-4- 43020]
FX Fund/Grant Support This research was supported by a research fund
   administered by Dankook University in the year 2020 (grant No. 2020-4-
   43020) . The funder had no role in the design, conduct, and reporting of
   this work.
CR APRAHAMIAN C, 1990, J TRAUMA, V30, P719, DOI 10.1097/00005373-199006000-00011
   Balduzzi S, 2019, EVID-BASED MENT HEAL, V22, P153, DOI 10.1136/ebmental-2019-300117
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker TH, 2021, BMC MED RES METHODOL, V21, DOI 10.1186/s12874-021-01381-z
   Boolaky KN, 2022, EUR J TRAUMA EMERG S, V48, P953, DOI 10.1007/s00068-020-01543-6
   Bradley M, 2014, AM SURGEON, V80, P768
   Brown LR, 2022, STATPEARLS
   BURCH JM, 1992, ANN SURG, V215, P476, DOI 10.1097/00000658-199205000-00010
   Burlew CC, 2012, J TRAUMA ACUTE CARE, V72, P235, DOI 10.1097/TA.0b013e318236b319
   Burlew CC, 2011, J TRAUMA, V70, P273, DOI 10.1097/TA.0b013e3182050eb7
   Chabot Elizabeth, 2017, Trauma Surg Acute Care Open, V2, pe000063, DOI [10.1136/tsaco-2016-000063, 10.1136/tsaco-2016-000063]
   Chavarria-Aguilar M, 2004, J TRAUMA, V56, P560, DOI 10.1097/01.TA.0000115065.39699.6A
   Chiara O, 2016, J TRAUMA ACUTE CARE, V80, P173, DOI 10.1097/TA.0000000000000882
   Coccolini F, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0167-4
   COHN SM, 1995, J TRAUMA, V39, P978, DOI 10.1097/00005373-199511000-00026
   Cristaudo A, 2017, AM SURGEON, V83, P191
   Dennis A, 2013, J TRAUMA ACUTE CARE, V74, P1486, DOI 10.1097/TA.0b013e3182924950
   Diaz Jose J Jr, 2004, Surg Infect (Larchmt), V5, P15, DOI 10.1089/109629604773860264
   Diaz JJ, 2010, J TRAUMA, V68, P1425, DOI 10.1097/TA.0b013e3181da0da5
   DuBose JJ, 2013, J TRAUMA ACUTE CARE, V74, P113, DOI 10.1097/TA.0b013e31827891ce
   Edwards JD, 2022, SURG INFECT, V23, P113, DOI 10.1089/sur.2021.262
   Einav S, 2021, CURR OPIN CRIT CARE, V27, P726, DOI 10.1097/MCC.0000000000000879
   Fernandez L, 1996, J TRAUMA, V40, P258, DOI 10.1097/00005373-199602000-00014
   Garner GB, 2001, AM J SURG, V182, P630, DOI 10.1016/S0002-9610(01)00786-3
   Georgoff P, 2013, J SURG RES, V181, P293, DOI 10.1016/j.jss.2012.07.011
   Godat L, 2013, WORLD J EMERG SURG, V8, DOI 10.1186/1749-7922-8-53
   Granger S, 2020, ANN ROY COLL SURG, V102, P519, DOI 10.1308/rcsann.2020.0105
   Hadeed JG, 2007, AM SURGEON, V73, P10
   Harvin JA, 2013, J TRAUMA ACUTE CARE, V74, P426, DOI 10.1097/TA.0b013e31827e2a96
   Heo Y, 2022, OUTCOMES ASS TEMPORA
   Hsu YP, 2018, SCI REP-UK, V8, DOI 10.1038/s41598-018-24482-0
   Hu P, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0204-3
   Huang Q, 2016, GASTROENT RES PRACT, V2016, DOI 10.1155/2016/2073260
   Hynes Allyson M, 2021, J Trauma Acute Care Surg, V91, P841, DOI 10.1097/TA.0000000000003245
   Jiang Jin-bo, 2006, Zhonghua Wei Chang Wai Ke Za Zhi, V9, P50
   Johnson JW, 2001, J TRAUMA, V51, P261, DOI 10.1097/00005373-200108000-00007
   Keel M. V.A.C., 2005, EUR J TRAUMA, V31, P488
   Kirkpatrick AW, 2015, ANN SURG, V262, P38, DOI 10.1097/SLA.0000000000001095
   Kruger H, 2021, S AFR J SURG, V59, P20, DOI 10.17159/2078-5151/2021/v59n1a3400
   Mahoney EJ, 2022, J Trauma Acute Care Surg, V93, P110, DOI [DOI 10.1097/TA.0000000000003683, 10.1097/TA.0000000000003683]
   Mayberry JC, 2004, J TRAUMA, V57, P157, DOI 10.1097/01.TA.0000102411.69521.80
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   Milne DM, 2021, CUREUS J MED SCIENCE, V13, DOI 10.7759/cureus.15489
   Nagy KK, 1996, AM SURGEON, V62, P331
   Navsaria P, 2013, WORLD J EMERG SURG, V8, DOI 10.1186/1749-7922-8-4
   Offner PJ, 2001, ARCH SURG-CHICAGO, V136, P676, DOI 10.1001/archsurg.136.6.676
   Ott MM, 2011, J TRAUMA, V70, P595, DOI 10.1097/TA.0b013e31820b5dbf
   Quyn AJ, 2012, COLORECTAL DIS, V14, pE429, DOI 10.1111/j.1463-1318.2012.03045.x
   Raeburn CD, 2001, AM J SURG, V182, P542, DOI 10.1016/S0002-9610(01)00821-2
   Rasilainen S, 2020, J TRAUMA ACUTE CARE, V89, P1136, DOI 10.1097/TA.0000000000002889
   Sánchez-Lozada Raúl, 2004, Gac. Méd. Méx, V140, P295
   Sharrock AE, 2016, INJURY, V47, P296, DOI 10.1016/j.injury.2015.09.008
   Smith JW, 2017, J AM COLL SURGEONS, V224, P396, DOI 10.1016/j.jamcollsurg.2016.12.047
   Smith JW, 2010, J AM COLL SURGEONS, V210, P658, DOI 10.1016/j.jamcollsurg.2010.01.014
   SMITH PC, 1992, J TRAUMA, V32, P16, DOI 10.1097/00005373-199201000-00004
   Sterne JAC, 2019, BMJ-BRIT MED J, V366, DOI 10.1136/bmj.l4898
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Ursua A., 2012, P IEEE, V100, DOI [10.1186/s13643-021-01626-4, DOI 10.1186/s13643-021-01626-4]
   Vertrees A, 2006, J AM COLL SURGEONS, V202, P762, DOI 10.1016/j.jamcollsurg.2006.02.008
   Vertrees A, 2008, J AM COLL SURGEONS, V207, P801, DOI 10.1016/j.jamcollsurg.2008.08.014
   Wang YF, 2019, WORLD J SURG, V43, P3044, DOI 10.1007/s00268-019-05166-w
   Weinberg JA, 2008, J TRAUMA, V65, P345, DOI 10.1097/TA.0b013e31817fa489
   Wells GA., 2020, NEWCASTLE OTTAWA SCA
   Willms AG, 2022, HERNIA, V26, P61, DOI 10.1007/s10029-020-02336-x
   Yeh KA, 1996, SOUTHERN MED J, V89, P497, DOI 10.1097/00007611-199605000-00010
NR 67
TC 6
Z9 9
U1 0
U2 4
PU KOREAN SURGICAL SOCIETY
PI SEOUL
PA 3304HO, 101 DONG, BROWNSTONE SEOUL, 335, JUNGMIN-DONG, JUNG-GU, SEOUL,
   100-859, SOUTH KOREA
SN 2288-6575
EI 2288-6796
J9 ANN SURG TREAT RES
JI Ann. Surg. Treat. Res.
PD APR
PY 2023
VL 104
IS 4
BP 237
EP 247
DI 10.4174/astr.2023.104.4.237
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA D7MD0
UT WOS:000970521900007
PM 37051156
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Fowler, JR
   Kleiner, MT
   Das, R
   Gaughan, JP
   Rehman, S
AF Fowler, J. R.
   Kleiner, M. T.
   Das, R.
   Gaughan, J. P.
   Rehman, S.
TI Assisted closure of fasciotomy wounds A DESCRIPTIVE SERIES AND CAUTION
   IN PATIENTS WITH VASCULAR INJURY
SO BONE & JOINT RESEARCH
LA English
DT Article
DE Fasciotomy; Negative pressure wound therapy; NPWT; Vessel loop closure;
   Infection; Complications
AB Introduction
   Negative pressure wound therapy (NPWT) and vessel loop assisted closure are two common methods used to assist with the closure of fasciotomy wounds. This retrospective review compares these two methods using a primary outcome measurement of skin graft requirement.
   Methods
   A retrospective search was performed to identify patients who underwent fasciotomy at our institution. Patient demographics, location of the fasciotomy, type of assisted closure, injury characteristics, need for skin graft, length of stay and evidence of infection within 90 days were recorded.
   Results
   A total of 56 patients met the inclusion criteria. Of these, 49 underwent vessel loop closure and seven underwent NPWT assisted closure. Patients who underwent NPWT assisted closure were at higher risk for requiring skin grafting than patients who underwent vessel loop closure, with an odds ratio of 5.9 (95% confidence interval 1.11 to 31.24). There was no difference in the rate of infection or length of stay between the two groups. Demographic factors such as age, gender, fracture mechanism, location of fasciotomy and presence of open fracture were not predictive of the need for skin grafting.
   Conclusion
   This retrospective descriptive case series demonstrates an increased risk of skin grafting in patients who underwent fasciotomy and were treated with NPWT assisted wound closure. In our series, vessel loop closure was protective against the need for skin grafting. Due to the small sample size in the NPWT group, caution should be taken when generalising these results. Further research is needed to determine if NPWT assisted closure of fasciotomy wounds truly leads to an increased requirement for skin grafting, or if the vascular injury is the main risk factor.
C1 [Fowler, J. R.; Kleiner, M. T.; Das, R.; Gaughan, J. P.; Rehman, S.] Temple Univ Hosp & Med Sch, Philadelphia, PA 19140 USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple
   University
RP Fowler, JR (通讯作者)，Temple Univ Hosp & Med Sch, 3401 N Broad St, Philadelphia, PA 19140 USA.
EM john.fowler@tuhs.temple.edu
RI Fowler, John/D-4849-2016
CR Almekinders L C, 1991, Orthop Rev, V20, P84
   Asgari MM, 2000, ANN PLAS SURG, V44, P225, DOI 10.1097/00000637-200044020-00017
   Barnea Y, 2006, INJURY, V37, P561, DOI 10.1016/j.injury.2006.02.056
   Baum TP, 1999, ANN PLAS SURG, V42, P337, DOI 10.1097/00000637-199903000-00019
   BERMAN SS, 1994, AM J SURG, V167, P435, DOI 10.1016/0002-9610(94)90130-9
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Galois L, 2002, Acta Orthop Belg, V68, P63
   HARRIS I, 1993, INJURY, V24, P565, DOI 10.1016/0020-1383(93)90040-D
   Harris IA, 2006, J TRAUMA, V60, P1330, DOI 10.1097/01.ta.0000196001.03681.c3
   Janzing HMJ, 2001, J ORTHOP TRAUMA, V15, P438, DOI 10.1097/00005131-200108000-00010
   Marek DJ, 2005, AM J SURG, V190, P123, DOI 10.1016/j.amjsurg.2005.05.038
   McQueen MM, 1996, J BONE JOINT SURG BR, V78B, P95, DOI 10.1302/0301-620X.78B1.0780095
   McQueen MM, 2000, J BONE JOINT SURG BR, V82B, P200, DOI 10.1302/0301-620X.82B2 .9799
   McQueen MM, 1996, J BONE JOINT SURG BR, V78B, P99, DOI 10.1302/0301-620X.78B1.0780099
   Medina Carlos, 2008, Hand (N Y), V3, P146, DOI 10.1007/s11552-007-9082-y
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Schnirring-Judge MA, 2009, J FOOT ANKLE SURG, V48, P692, DOI 10.1053/j.jfas.2009.07.011
   Webb Lawrence X, 2002, J Am Acad Orthop Surg, V10, P303
   Williams PR, 1998, INJURY, V29, P229, DOI 10.1016/S0020-1383(97)00193-9
   Yang Charlie C, 2006, J Surg Orthop Adv, V15, P19
   Zannis J, 2009, ANN PLAS SURG, V62, P407, DOI 10.1097/SAP.0b013e3181881b29
   Zorrilla P, 2005, J TRAUMA, V59, P1515, DOI 10.1097/01.ta.0000199242.24511.30
NR 24
TC 16
Z9 20
U1 0
U2 1
PU BRITISH EDITORIAL SOC BONE JOINT SURGERY
PI LONDON
PA 22 BUCKINGHAM STREET, LONDON WC2N 6ET, ENGLAND
SN 2046-3758
J9 BONE JOINT RES
JI Bone Jt. Res.
PD MAR
PY 2012
VL 1
IS 3
BP 31
EP 35
DI 10.1302/2046-3758.13.2000022
PG 5
WC Cell & Tissue Engineering; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Orthopedics
GA V35GW
UT WOS:000209139400002
PM 23610668
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Tahir, S
   Parvin, F
   Wang, M
   Deva, AK
   Vickery, K
   Hu, HH
AF Tahir, Shamaila
   Parvin, Farhana
   Wang, Matthew
   Deva, Anand K.
   Vickery, Karen
   Hu, Honghua
TI The efficacy of antimicrobial solutions against multispecies bacterial
   biofilm with or without negative pressure wound therapy in an in vitro
   wound model
SO JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
LA English
DT Article
ID RAPID IDENTIFICATION; SITU HYBRIDIZATION
AB Objectives: Biofilm is the major challenge in chronic wound management. Instilling a wound cleansing solution aids in wound bed cleaning and infectious pathogen elimination. Negative pressure wound therapy (NPWT) improves the wound-healing process. This study investigated the efficacy of two antimicrobials (Vashe Wound Cleanser and Prontosan Wound Irrigation Solution) against a multispecies bacterial biofilm with or without NPWT in an in vitro wound model. Methods; A mixed multispecies biofilm containing Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, and Acinetobacter baumannii was developed and verified by scanning electron microscopy and fluorescent in situ hybridization. The efficacy of Vashe and Prontosan against multispecies biofilm with or without NPWT was evaluated by colony-forming unit (cfu) of each species and total bacterial number, and visually confirmed by live/dead stain and confocal microscopy. Results: Prontosan reduced biofilm cell numbers significantly: 6 instils over 24 h resulting in 3.86 +/- 0.14 cfu log10 reduction without NPWT and 4.75 +/- 0.13 cfu log10 reduction combined with NPWT (P < 0.01) and 12 instils over 48 h resulting in 5.24 +/- 0.11 cfu log10 reduction without NPWT and biofilm eradication with NPWT (P < 0.001). NPWT alone or combined with Vashe failed to reduce multispecies biofilm numbers significantly over 24 or 48 h. Conclusions: Prontosan significantly reduced biofilm cell numbers, with better efficacy over 48 than 24 h, emphasizing the necessity for persistent and robust treatment. NPWT enhanced the effectiveness of Prontosan instillation. However, NPWT alone or combined with Vashe showed limited efficacy and difficulty when combating the multispecies biofilm in vitro.
C1 [Tahir, Shamaila; Parvin, Farhana; Deva, Anand K.; Vickery, Karen; Hu, Honghua] Macquarie Univ, Macquarie Med Sch, Sydney, NSW 2109, Australia.
   [Wang, Matthew] Univ New South Wales, Fac Med & Hlth, Sydney, NSW 2052, Australia.
   [Hu, Honghua] Zhejiang Univ, Innovat Ctr Translat Pharm, Jinhua Inst, Jinhua 321016, Peoples R China.
   [Hu, Honghua] Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Peoples R China.
C3 Macquarie University; University of New South Wales Sydney; Zhejiang
   University; Zhejiang University
RP Hu, HH (通讯作者)，Macquarie Univ, Macquarie Med Sch, Sydney, NSW 2109, Australia.; Hu, HH (通讯作者)，Zhejiang Univ, Innovat Ctr Translat Pharm, Jinhua Inst, Jinhua 321016, Peoples R China.; Hu, HH (通讯作者)，Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Peoples R China.
EM honghuahu@zju.edu.cn
RI ; Hu, Honghua/K-4525-2012
OI Vickery, Karen/0000-0003-0998-1370; Deva, Anand/0000-0002-0314-7177; 
FU KCI Medical Australia Pty Ltd.
FX This research was funded by KCI Medical Australia Pty Ltd. The funders
   had no role in the study design; data collection, analyses, and
   interpretation; manuscript preparation; or decision on results to
   publish.
CR Ahmed El-Shanshory, 2014, Journal of Donghua University (English Edition), V31, P566
   Block MS, 2020, J ORAL MAXIL SURG, V78, P1461, DOI 10.1016/j.joms.2020.06.029
   Durante CM, 2014, MINERVA CHIR, V69, P283
   Frickmann H, 2011, EUR J MICROBIOL IMMU, V1, P289, DOI 10.1556/EuJMI.1.2011.4.4
   Gul A, 2021, MEMBRANES-BASEL, V11, DOI 10.3390/membranes11120908
   Hamza KH, 2023, PHARMACEUTICS, V15, DOI 10.3390/pharmaceutics15051518
   Hu HH, 2018, AESTHET SURG J, V38, P723, DOI 10.1093/asj/sjx213
   Jnana A, 2020, APPL ENVIRON MICROB, V86, DOI 10.1128/AEM.02608-19
   Kempf VAJ, 2000, J CLIN MICROBIOL, V38, P830, DOI 10.1128/JCM.38.2.830-838.2000
   Li TT, 2020, EXP THER MED, V20, P512, DOI 10.3892/etm.2020.8679
   Li TT, 2016, EXP THER MED, V11, P769, DOI 10.3892/etm.2016.3008
   Oropallo A, 2021, J WOUND CARE, V30, P854, DOI 10.12968/jowc.2021.30.10.854
   Pranantyo D, 2024, NAT COMMUN, V15, DOI 10.1038/s41467-024-44968-y
   Shang SL, 2024, BIOACT MATER, V34, P298, DOI 10.1016/j.bioactmat.2023.12.026
   Singh D, 2017, WOUNDS, V29, P175
   Tahir S, 2018, MATERIALS, V11, DOI 10.3390/ma11050811
   Tavares A, 2008, J CLIN MICROBIOL, V46, P3097, DOI 10.1128/JCM.00910-08
   Tingting S, 2023, FRONT SURG, V10, DOI 10.3389/fsurg.2023.1080838
   Valente PMDS, 2016, INT WOUND J, V13, P130, DOI 10.1111/iwj.12248
   Wang GQ, 2018, ANTON LEEUW INT J G, V111, P1557, DOI 10.1007/s10482-018-1045-5
   White EK, 2023, CSH PERSPECT BIOL, V15, DOI 10.1101/cshperspect.a041218
   Yoshioka T, 2018, SURG CASE REP, V4, DOI 10.1186/s40792-018-0493-5
NR 22
TC 0
Z9 2
U1 1
U2 6
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0305-7453
EI 1460-2091
J9 J ANTIMICROB CHEMOTH
JI J. Antimicrob. Chemother.
PD OCT 3
PY 2024
VL 79
IS 12
BP 3178
EP 3185
DI 10.1093/jac/dkae338
EA OCT 2024
PG 8
WC Infectious Diseases; Microbiology; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Microbiology; Pharmacology & Pharmacy
GA P0Y2Q
UT WOS:001328335800001
PM 39361487
DA 2026-07-24
ER

PT J
AU Tang, NI
   Li, H
   Chow, Y
   Blake, W
AF Tang, Nicholas
   Li, Henry
   Chow, Yvonne
   Blake, William
TI Non-operative adjuncts for the prevention of mastectomy skin flap
   necrosis: a systematic review and meta-analysis
SO ANZ JOURNAL OF SURGERY
LA English
DT Review
DE breast cancer; breast reconstruction; flaps; mastectomy; negative
   pressure wound therapy
ID INCISION MANAGEMENT-SYSTEM; SPARING MASTECTOMY; BREAST RECONSTRUCTION;
   NITROGLYCERIN OINTMENT; DIMETHYL-SULFOXIDE; COMPLICATIONS; ISCHEMIA;
   SURVIVAL; RISK
AB Background Native skin flap necrosis is a potentially devastating complication following skin-sparing or nipple-sparing mastectomy with a reported incidence of as high as 30%. Treatment depends on the depth and extent of tissue necrosis and can range from dressings to surgical debridement and further reconstruction. This can have implications on patient physical and psychological wellbeing as well as cost of treatment. This study aims to identify and appraise cost-effective non-surgical adjuncts for the prevention of native skin flap necrosis. Methods A systematic review was performed using the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement and structured around existing recommended guidelines. A search of MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature and ClinicalTrials.gov was performed with the medical subject headings 'mastectomy' and 'flap necrosis'. After exclusion, 12 articles were selected for review and analysed. Results A total of 8439 mastectomies were performed on 7895 patients. Preventative non-surgical adjuncts that demonstrated statistically significant reduction in mastectomy flap necrosis included topical nitroglycerin ointment (P = 0.000), closed-Incision negative pressure wound therapy (P = 0.000), topical dimethylsulfoxide ointment (P = 0.03), oral cilostazol (P = 0.032), and local heat pre-conditioning (P = 0.047). Conclusions This study identifies multiple adjuncts that may aid in preventing mastectomy skin flap necrosis, especially in high-risk patients. Further studies could aim to define standardized protocols and compare the various adjuncts in different circumstances.
C1 [Tang, Nicholas; Li, Henry; Chow, Yvonne; Blake, William] Monash Hlth, Dandenong Hosp, Dept Plast & Reconstruct Surg, Melbourne, Vic, Australia.
C3 Monash Health; Dandenong Hospital
RP Tang, NI (通讯作者)，Monash Hlth, Dandenong Hosp, 135 David St, Melbourne, Vic 3175, Australia.
EM nsjtang@gmail.com
OI Blake, William/0009-0000-1533-1572
CR ADAMSON JE, 1967, PLAST RECONSTR SURG, V39, P142, DOI 10.1097/00006534-196702000-00003
   Amemori S, 2006, J GASTROENTEROL, V41, P444, DOI 10.1007/s00535-006-1792-3
   Aral M, 2015, J RECONSTR MICROSURG, V31, P487, DOI 10.1055/s-0035-1554938
   Atalay C, 2009, BREAST CANCER RES TR, V117, P611, DOI 10.1007/s10549-009-0335-z
   Atkins BZ, 2011, INT WOUND J, V8, P56, DOI 10.1111/j.1742-481X.2010.00743.x
   Beer GM, 2002, CANCER, V94, P1619, DOI 10.1002/cncr.10429
   Burusapat Chairat, 2015, Ann Surg Innov Res, V9, P2, DOI [10.1186/s13022-015-0011-4, 10.1186/s13022-015-0011-4]
   Carlson GW, 2011, INT J SURG ONCOL, V2011, DOI 10.1155/2011/396901
   Celen O, 2005, ACTA CHIR BELG, V105, P287, DOI 10.1080/00015458.2005.11679718
   Chang DW, 2000, PLAST RECONSTR SURG, V105, P2374, DOI 10.1097/00006534-200006000-00010
   Chapman Therese M, 2003, Am J Cardiovasc Drugs, V3, P117, DOI 10.2165/00129784-200303020-00006
   Chou R., 2010, APPENDIX 5 U S PREVE
   Chun YS, 2011, AM J SURG, V201, P160, DOI 10.1016/j.amjsurg.2009.12.011
   Clair JS., 2005, ADV PATIENT SAFETY R
   da Mota DSC, 2018, J SURG RES, V228, P253, DOI 10.1016/j.jss.2018.03.014
   Davies K, 2011, BREAST, V20, P21, DOI 10.1016/j.breast.2010.06.006
   Davis R E, 1999, Arch Facial Plast Surg, V1, P27, DOI 10.1001/archfaci.1.1.27
   FAN ZL, 1993, J SURG ONCOL, V53, P210, DOI 10.1002/jso.2930530319
   Ferrando PM, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001732
   FRANKS AG, 1982, LANCET, V1, P76
   Gabriel A, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001880
   Garwood ER, 2009, ANN SURG, V249, P26, DOI 10.1097/SLA.0b013e31818e41a7
   Gdalevitch P, 2015, PLAST RECONSTR SURG, V135, P1530, DOI 10.1097/PRS.0000000000001237
   Ghosh M, 2020, International Journal of Research, V7, P335
   Harder Y, 2004, J SURG RES, V119, P100, DOI 10.1016/j.jss.2003.11.002
   Hawkins RB, 2019, J SURG RES, V240, P227, DOI 10.1016/j.jss.2019.02.046
   Huang Jin-Wei, 2015, Maxillofac Plast Reconstr Surg, V37, P20, DOI [10.1186/s40902-015-0017-1, 10.1186/s40902-015-0017-1]
   Hultman CS, 2003, ANN PLAS SURG, V50, P249, DOI 10.1097/01.SAP.0000046784.70583.E1
   Jeon FHK, 2018, BJS OPEN, V2, P175, DOI 10.1002/bjs5.61
   Kanuri A, 2014, PLAST RECONSTR SURG, V133, p448E, DOI 10.1097/PRS.0000000000000025
   Kim DY, 2016, PLAST RECONSTR SURG, V138, P558, DOI 10.1097/PRS.0000000000002431
   Kim JH, 2020, INT WOUND J, V17, P1310, DOI 10.1111/iwj.13393
   Kim JH, 2019, J ARTHROPLASTY, V34, P2804, DOI 10.1016/j.arth.2019.06.020
   Kroll SS, 1999, PLAST RECONSTR SURG, V104, P421, DOI 10.1097/00006534-199908000-00015
   Kutun S, 2010, S AFR J SURG, V48, P119
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   McCarthy CM, 2008, PLAST RECONSTR SURG, V121, P1886, DOI 10.1097/PRS.0b013e31817151c4
   MCCORD JM, 1985, NEW ENGL J MED, V312, P159
   Mehta S, 2013, J PLAST RECONSTR AES, V66, P1676, DOI 10.1016/j.bjps.2013.07.034
   Mlodinow AS, 2014, J PLAST SURG HAND SU, V48, P322, DOI 10.3109/2000656X.2014.884973
   Moher D, 2009, J CLIN EPIDEMIOL, V62, P1006, DOI 10.1016/j.jclinepi.2009.06.005
   Özdemir A, 2017, J PLAST SURG HAND SU, V51, P217, DOI 10.1080/2000656X.2016.1237958
   Peeker R, 2000, J UROLOGY, V164, P1912, DOI 10.1016/S0022-5347(05)66916-9
   Pinsolle V, 2006, J PLAST RECONSTR AES, V59, P1017, DOI 10.1016/j.bjps.2006.03.057
   RandLuby L, 1996, ANN SURG, V224, P583, DOI 10.1097/00000658-199610000-00016
   Shen J, 2008, AM SURGEON, V74, P902
   Shinichi A., 2014, ONLINE KENSAKU, V35, P154
   Slavin SA, 1998, PLAST RECONSTR SURG, V102, P49, DOI 10.1097/00006534-199807000-00008
   Spear SL, 2007, PLAST RECONSTR SURG, V119, P788, DOI 10.1097/01.prs.0000252003.14537.d2
   Sue GR, 2017, ANN PLAS SURG, V78, pS208, DOI 10.1097/SAP.0000000000001045
   TOTH BA, 1991, PLAST RECONSTR SURG, V87, P1048, DOI 10.1097/00006534-199106000-00006
   Turin SY, 2018, PLAST RECONSTR SURG, V142, p264E, DOI 10.1097/PRS.0000000000004633
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   WONG AF, 1992, J PEDIATR-US, V121, P980, DOI 10.1016/S0022-3476(05)80356-7
   Yalanis GC, 2015, PRS-GLOB OPEN, V3, DOI 10.1097/GOX.0000000000000408
   Yun MH, 2017, ARCH PLAST SURG-APS, V44, P509, DOI 10.5999/aps.2017.00934
NR 57
TC 14
Z9 15
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1445-1433
EI 1445-2197
J9 ANZ J SURG
JI ANZ J. Surg.
PD JAN
PY 2023
VL 93
IS 1-2
BP 65
EP 75
DI 10.1111/ans.18146
EA NOV 2022
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 9A2CO
UT WOS:000882871700001
PM 36373495
DA 2026-07-24
ER

PT J
AU Griffin, LP
   Sifuentes, MM
AF Griffin, Leah P.
   Sifuentes, Mikaela M.
TI Remote Monitoring Saves Costs in Outpatient Negative Pressure Wound
   Therapy
SO AMERICAN JOURNAL OF MANAGED CARE
LA English
DT Article
ID CLOSURE; BURDEN; ULCERS; CARE
AB OBJECTIVES: In the outpatient setting, combining remote therapy monitoring (RTM) with negative pressure wound therapy (NPWT) can support improved adherence to prescribed therapy. A recent study reported that patients receiving NPWT with RTM required fewer therapy days than patients receiving NPWT alone, possibly reducing costs of care. Our objective was to determine whether RTM reduced 90-day costs in patients undergoing NPWT.
   STUDY DESIGN: We conducted a retrospective cohort study of patients receiving NPWT with or without RTM in the postacute setting.
   METHODS: Patients beginning NPWT between March 2018 and May 2019 were included. Payer claims data were collected and analyzed with t test for continuous variables and chi 2 test for categorical variables. Multiple regressions were performed to control for confounding variables.
   RESULTS: Of the 1105 patients included the study, 675 (61%) received RTM and 430 (39%) did not. RTM patients were significantly older (P < .0001), had more ulcers (P = .0004), and had higher Charlson Comorbidity Index (CCI) scores (P < .0001). The unadjusted mean 90-day wound-related cost was not significantly higher for non-RTM patients than for RTM patients (P = .0799). After controlling for differences in age, payer type, CCI score, and wound type, there was a significant reduction in 90-day wound-related costs in the RTM group compared with the non-RTM group ($11,119 vs $14,752; P = .0131). The RTM group had higher NPWT costs ($3757 vs $3289; P = .0035) but lower wound related non-NPWT costs ($7361 vs $11,462; P = .0045).
   CONCLUSIONS: This study demonstrated the value of RTM in supporting NPWT adherence and decreasing the costs of wound care in these patients.
C1 [Griffin, Leah P.; Sifuentes, Mikaela M.] 3M Co, LPG MMS, San Antonio, TX USA.
C3 3M
RP Griffin, LP (通讯作者)，3M Co, 12930 W Interstate 10, San Antonio, TX 78249 USA.
EM lpgriffin@mmm.com
RI Sifuentes, Mikaela/AAJ-1776-2021
OI Sifuentes, Mikaela/0000-0002-7914-4183
CR [Anonymous], 2020, PUBL POLL EM CAR AM
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Chan B, 2017, J WOUND CARE, V26, pS4, DOI 10.12968/jowc.2017.26.Sup4.S4
   CHARLSON ME, 1987, J CHRON DIS, V40, P373, DOI 10.1016/0021-9681(87)90171-8
   Chisholm-Burns MA, 2012, J AM PHARM ASSOC, V52, P823, DOI 10.1331/JAPhA.2012.11088
   Fife CE, 2012, WOUNDS, V24, P10
   Gould L, 2015, J AM GERIATR SOC, V63, P427, DOI 10.1111/jgs.13332
   Griffin L, 2019, WOUNDS, V31, pE9
   Griffin L, 2018, WOUNDS, V30, pE81
   Griffin Leah, 2018, Wounds, V30, pE29
   Guest JF, 2017, J WOUND CARE, V26, P292, DOI 10.12968/jowc.2017.26.6.292
   Mehrotra A., The impact of the COVID-19 pandemic on outpatient visits: a rebound emerges, DOI [10.26099/ds9e-jm36, DOI 10.26099/DS9E-JM36, DOI 10.26099/DS9--JM36]
   Monsen C, 2014, J VASC SURG, V59, P145, DOI 10.1016/j.jvs.2013.06.073
   Nussbaum SR, 2018, VALUE HEALTH, V21, P27, DOI 10.1016/j.jval.2017.07.007
   Olsson M, 2019, WOUND REPAIR REGEN, V27, P114, DOI 10.1111/wrr.12683
   Rogers LC, 2020, WOUNDS, V32, P178
   Seidel D, 2020, JAMA SURG, V155, P469, DOI 10.1001/jamasurg.2020.0414
   Sen CK, 2019, ADV WOUND CARE, V8, P39, DOI 10.1089/wound.2019.0946
   Stanton T, 2019, S ADV WOUND CAR FALL
NR 19
TC 3
Z9 3
U1 0
U2 0
PU MANAGED CARE & HEALTHCARE COMMUNICATIONS LLC
PI PLAINSBORO
PA 666 PLAINSBORO RD, STE 300, PLAINSBORO, NJ 08536 USA
SN 1088-0224
J9 AM J MANAG CARE
JI Am. J. Manag. Care
PD FEB
PY 2022
VL 28
IS 2
BP 53
EP 58
DI 10.37765/ajmc.2022.88738
PG 6
WC Health Care Sciences & Services; Health Policy & Services; Medicine,
   General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Health Care Sciences & Services; General & Internal Medicine
GA YX6ZT
UT WOS:000754249400001
PM 35139289
DA 2026-07-24
ER

PT J
AU Nuutila, K
   Eriksson, E
AF Nuutila, Kristo
   Eriksson, Elof
TI Moist Wound Healing with Commonly Available Dressings
SO ADVANCES IN WOUND CARE
LA English
DT Review
DE absorptive capacity; antimicrobials; moist wound dressings; moist wound
   healing; negative pressure wound therapy; wear time; water vapor
   transmission rate
ID VAPOR TRANSMISSION RATE; FOAM DRESSINGS; SKIN WOUNDS; INFLAMMATION; WET;
   SILVER; HONEY; MICROENVIRONMENT; INFECTION; THERAPY
AB Significance: A moist wound environment has several benefits that result in faster and better quality of healing. It facilitates autolytic debridement, reduces pain, reduces scarring, activates collagen synthesis, facilitates and promotes keratinocyte migration over the wound surface, and supports the presence and function of nutrients, growth factors, and other soluble mediators in the wound microenvironment.
   Recent Advances: Wound dressings can be utilized to create, maintain, and control a moist environment for healing. Moist wound dressings can be divided into films, foams, hydrocolloids, hydrogels, and alginates. We are also including negative pressure wound therapy systems in the moist dressings.
   Critical Issues: An optimal wound dressing should provide a moist environment and have an optimal water vapor transmission rate (WVTR) and absorptive capacity. It should also protect the wound against trauma and contamination and be easy to apply, painless to remove, and esthetically acceptable or even pleasing.
   Future Directions: Interventions, particularly dressing changes, by medical caregivers are labor intensive and expensive and there should be a continuous effort to reduce their number per week. Smart dressings with integrated microsensors and delivery capabilities that would allow wireless real-time monitoring and treatment of the wound would be very advantageous. This way the state of the wound as well as the wear time of the dressing could be assessed without dressing removal or visit to the wound care center. In addition, an ability to adjust the WVTRs to the exudate level of the wound (or having a large absorptive capacity without changing the WVTR) would be useful. This feature would guarantee an optimal level of hydration of the wound surface throughout the treatment.
C1 [Nuutila, Kristo] Harvard Med Sch, Brigham & Womens Hosp, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
   [Eriksson, Elof] Harvard Med Sch, Dept Surg, Boston, MA 02115 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard Medical School; Harvard University; Harvard
   Medical School
RP Nuutila, K (通讯作者)，Harvard Med Sch, Brigham & Womens Hosp, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
EM kristo.nuutila@gmail.com
CR Anghel EL, 2016, PLAST RECONSTR SURG, V138, p129S, DOI 10.1097/PRS.0000000000002645
   Atkin Leanne, 2016, Br J Nurs, V25, pS40, DOI 10.12968/bjon.2016.25.20.s40
   Balakrishnan B, 2005, BIOMATERIALS, V26, P6335, DOI 10.1016/j.biomaterials.2005.04.012
   Bechert Kari, 2009, J Am Col Certif Wound Spec, V1, P65, DOI 10.1016/j.jcws.2008.12.001
   Bolton L L, 2000, Ostomy Wound Manage, V46, p51S
   Bowler PG, 2001, CLIN MICROBIOL REV, V14, P244, DOI 10.1128/CMR.14.2.244-269.2001
   BREUING K, 1992, J SURG RES, V52, P50, DOI 10.1016/0022-4804(92)90278-8
   Broussard KC, 2013, AM J CLIN DERMATOL, V14, P449, DOI 10.1007/s40257-013-0046-4
   Brown-Etris Marie, 2008, Adv Skin Wound Care, V21, P169, DOI 10.1097/01.ASW.0000305429.01413.f8
   Bunyan J, 1941, Br Med J, V2, P1
   Carter MJ, 2010, J AM ACAD DERMATOL, V63, P668, DOI 10.1016/j.jaad.2009.09.007
   Cefalu JE, 2017, CRIT CARE NURS CLIN, V29, P81, DOI 10.1016/j.cnc.2016.09.009
   da Cunha BR, 2019, J CANCER, V10, P4574, DOI 10.7150/jca.21780
   Daly LT, 2016, PLAST RECONSTR SURG, V138, p856E, DOI 10.1097/PRS.0000000000002633
   Deutsch CJ, 2017, BRIT J HOSP MED, V78, pC103, DOI 10.12968/hmed.2017.78.7.C103
   Dhivya S, 2015, BIOMEDICINE-TAIWAN, V5, P24, DOI 10.7603/s40681-015-0022-9
   Dissemond J, 2015, J WOUND CARE, V24, P53, DOI 10.12968/jowc.2015.24.2.53
   Domres B, 2007, Ann Burns Fire Disasters, V20, P149
   Doughty D, 2005, NURS CLIN N AM, V40, P217, DOI 10.1016/j.cnur.2004.09.012
   Dumville JC, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009099.pub2
   Eriksson E, 2004, AM J SURG, V188, p36S, DOI 10.1016/S0002-9610(03)00295-2
   Eriksson E, 1996, ANN PLAS SURG, V36, P80, DOI 10.1097/00000637-199601000-00016
   Field F K, 1994, Am J Surg, V167, p2S
   FORREST RD, 1982, J ROY SOC MED, V75, P198
   Gethin G, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008599.pub2
   Grolman JM, 2019, J BURN CARE RES, V40, P900, DOI 10.1093/jbcr/irz113
   Gurtner GC, 2008, NATURE, V453, P314, DOI 10.1038/nature07039
   Gurunluoglu R, 2003, WORLD J SURG, V27, P18, DOI 10.1007/s00268-002-6464-8
   Hasatsri S, 2018, DERMAT RES PRACT, V2018, DOI 10.1155/2018/9367034
   Hebra F., 1861, ALLGEMEINE WIENER ME, V6, P351
   HINMAN CD, 1963, NATURE, V200, P377, DOI [10.1038/200377a0, 10.1038/200378a0]
   Hong, 2017, TEXT RES J, P87
   Hudson DA, 2015, INT WOUND J, V12, P195, DOI 10.1111/iwj.12080
   HUTCHINSON JJ, 1991, J HOSP INFECT, V17, P83, DOI 10.1016/0195-6701(91)90172-5
   James, 2003, J WOUND OSTOMY CONT, V30, pS21
   Jee JP, 2019, INT J NANOMED, V14, P5449, DOI 10.2147/IJN.S213883
   Jiao WX, 2019, MOLECULES, V24, DOI 10.3390/molecules24234374
   Jones V, 2006, BMJ-BRIT MED J, V332, P777, DOI 10.1136/bmj.332.7544.777
   Junker JPE, 2013, ADV WOUND CARE, V2, P348, DOI 10.1089/wound.2012.0412
   Kalemikerakis J, 2012, J BUON, V17, P560
   Khasriya, 2006, BMJ-BRIT MED J, V332, P638
   KICKHOFEN B, 1986, BIOMATERIALS, V7, P67, DOI 10.1016/0142-9612(86)90092-X
   Kruse CR, 2015, WOUND REPAIR REGEN, V23, P456, DOI 10.1111/wrr.12303
   Lairet KF, 2014, J BURN CARE RES, V35, P214, DOI 10.1097/BCR.0b013e31829b3338
   LAWRENCE JC, 1982, INJURY, V13, P500, DOI 10.1016/0020-1383(82)90166-8
   Lund-Nielsen B, 2011, WOUND REPAIR REGEN, V19, P664, DOI 10.1111/j.1524-475X.2011.00735.x
   Lutz JB, 2011, OSTOMY WOUND MANAG, V57, P28
   Malmsjo Malin, 2014, Eplasty, V14, pe15
   Mandal Manisha Deb, 2011, Asian Pacific Journal of Tropical Biomedicine, V1, P154, DOI 10.1016/S2221-1691(11)60016-6
   Mennini N, 2016, J WOUND CARE, V25, P428, DOI 10.12968/jowc.2016.25.8.428
   Metzger Stephanie, 2004, Home Healthc Nurse, V22, P586, DOI 10.1097/00004045-200409000-00003
   Molan P, 2015, WOUNDS, V27, P141
   Nuutila K, 2020, ADV WOUND CARE, V9, P48, DOI 10.1089/wound.2019.1018
   Nuutila K, 2019, WOUND REPAIR REGEN, V27, P162, DOI 10.1111/wrr.3
   Nuutila K, 2019, MIL MED, V184, pE373, DOI 10.1093/milmed/usy242
   Nuutila K, 2017, PLAST RECONSTR SURG, V140, P306, DOI 10.1097/PRS.0000000000003516
   Pang Q, 2020, ADV SCI, V7, DOI 10.1002/advs.201902673
   Parker N., US Patent, Patent No. [8,978,265, 8978265]
   Patmo ASP, 2014, ADV WOUND CARE, V3, P383, DOI 10.1089/wound.2013.0510
   Pott FS, 2014, REV LAT-AM ENFERM, V22, P511, DOI 10.1590/0104-1169.3480.2445
   Qiao BB, 2020, BIOMATER SCI-UK, V8, P1649, DOI 10.1039/c9bm02060h
   QUEEN D, 1987, BIOMATERIALS, V8, P367, DOI 10.1016/0142-9612(87)90007-X
   Reish RG, 2009, WOUND REPAIR REGEN, V17, P806, DOI 10.1111/j.1524-475X.2009.00546.x
   Rosique RG, 2015, INT J INFLAMM, V2015, DOI 10.1155/2015/316235
   Salmeron-Gonzalez Enrique, 2018, Plast Surg Nurs, V38, P73, DOI [10.1097/psn.0000000000000218, 10.1097/PSN.0000000000000218]
   Schulze H J, 2001, J Wound Care, V10, P511
   Sim W, 2018, ANTIBIOTICS-BASEL, V7, DOI 10.3390/antibiotics7040093
   Singh M, 2016, WOUND REPAIR REGEN, V24, P820, DOI 10.1111/wrr.12461
   Singh M, 2016, PLAST RECONSTR SURG, V137, p92E, DOI 10.1097/PRS.0000000000001871
   SMITH DJ, 1994, AM J SURG, V167, pS49, DOI 10.1016/0002-9610(94)90012-4
   Sood A, 2014, ADV WOUND CARE, V3, P511, DOI 10.1089/wound.2012.0401
   Struik GM, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0195715
   Svensjö T, 2000, PLAST RECONSTR SURG, V106, P602, DOI 10.1097/00006534-200009030-00012
   Tamayol A, 2016, ADV HEALTHC MATER, V5, P711, DOI 10.1002/adhm.201500553
   Thomas S., 1990, Wound management and dressings
   Vogt P.M., 1995, Wound Healing and Skin Physiology, P643, DOI DOI 10.1007/978-3-642-77882-763
   VOGT PM, 1995, ANN PLAS SURG, V34, P493, DOI 10.1097/00000637-199505000-00007
   Vranckx JJ, 2002, PLAST RECONSTR SURG, V110, P1680, DOI 10.1097/00006534-200212000-00009
   Wang GQ, 2018, BIOMED RES INT, V2018, DOI 10.1155/2018/9496183
   Waring M., 2013, WHAT IS CURRENT STAT, V8, P21
   Wiegand C, 2015, CHRONIC WOUND CARE M, V2, P101, DOI 10.2147/CWCMR.S60315
   WINTER GD, 1962, NATURE, V193, P293, DOI 10.1038/193293a0
   WU P, 1995, BIOMATERIALS, V16, P171, DOI 10.1016/0142-9612(95)92114-L
   Wu P, 1996, BIOMATERIALS, V17, P1373, DOI 10.1016/0142-9612(96)87277-2
   Xu R, 2016, SCI REP-UK, V6, DOI 10.1038/srep24596
   Xu Z., 2020, J MATER CHEM B, V3, P3634
   Xue ML, 2015, ADV WOUND CARE, V4, P119, DOI 10.1089/wound.2013.0485
   Yang L, 2018, J BURN CARE RES, V39, P790, DOI 10.1093/jbcr/irx051
   Yusof NLBM, 2003, J BIOMED MATER RES A, V66A, P224, DOI 10.1002/jbm.a.10545
   Zehrer CL, 2014, INT WOUND J, V11, P681, DOI 10.1111/iwj.12030
   Zhao G, 2013, ADV WOUND CARE, V2, P389, DOI 10.1089/wound.2012.0381
   Zuhaili B, 2010, PLAST RECONSTR SURG, V125, P855, DOI 10.1097/PRS.0b013e3181ccdc42
NR 92
TC 516
Z9 570
U1 19
U2 282
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD DEC 1
PY 2021
VL 10
IS 12
BP 685
EP 698
DI 10.1089/wound.2020.1232
EA FEB 2021
PG 14
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA US6EF
UT WOS:000656636200001
PM 32870777
OA Green Submitted, hybrid
HC Y
HP N
DA 2026-07-24
ER

PT J
AU Ren, SY
   Liu, YS
   Zhu, GJ
   Liu, M
   Shi, SH
   Ren, XD
   Hao, YG
   Gao, RD
AF Ren, Shi-Yan
   Liu, Yong-Sheng
   Zhu, Guo-Jian
   Liu, Meng
   Shi, Shao-Hui
   Ren, Xiao-Dong
   Hao, Ya-Guang
   Gao, Rong-Ding
TI Strategies and challenges in the treatment of chronic venous leg ulcers
SO WORLD JOURNAL OF CLINICAL CASES
LA English
DT Review
DE Chronic venous leg ulcers; Debridement; Compression; Negative pressure
   wound therapy; Autologous split-thickness skin grafting; Hair punch
   graft; Platelet-rich plasma; Advanced wound care therapies
ID HUMAN AMNION/CHORION MEMBRANE; PRESSURE WOUND THERAPY; THICKNESS
   SKIN-GRAFT; PLATELET-RICH PLASMA; VASCULAR FRACTION CELLS; MESENCHYMAL
   STEM-CELL; COMPRESSION THERAPY; FOAM SCLEROTHERAPY; TOPICAL TIMOLOL;
   MANAGEMENT
AB Evaluating patients with chronic venous leg ulcers (CVLUs) is essential to find the underlying etiology. The basic tenets in managing CVLUs are to remove the etiological causes, to address systemic and metabolic conditions, to examine the ulcers and artery pulses, and to control wound infection with debridement and eliminating excessive pressure on the wound. The first-line treatments of CVLUs remain wound care, debridement, bed rest with leg elevation, and compression. Evidence to support the efficacy of silver-based dressings in healing CVLUs is unavailable. Hydrogen peroxide is harmful to the growth of granulation tissue in the wound. Surgery options include a high ligation with or without stripping or ablation of the GSVs depending on venous reflux or insufficiency. Yet, not all CVLUs are candidates for surgical treatment because of comorbidities. When standard care of wound for 4 wk failed to heal CVLUs effectively, use of advanced wound care should be considered based on the available evidence. Negative pressure wound therapy facilitates granulation tissue development, thereby helping closure of CVLUs. Autologous split-thickness skin grafting is still the gold standard approach to close huge CVLUs. Hair punch graft appears to have a better result than traditional hairless punch graft for CVLUs. Application of adipose tissue or placenta-derived mesenchymal stem cells is a promising therapy for wound healing. Autologous platelet-rich plasma provides an alternative strategy for surgery for safe and natural healing of the ulcer. The confirmative efficacy of current advanced ulcer therapies needs more robust evidence.
C1 [Ren, Shi-Yan] China Med Univ, Dept Gen Surg & Vasc Surg, Aviat Gen Hosp, 2 Beiyuan Rd, Beijing 100012, Peoples R China.
   [Liu, Yong-Sheng] Aviat Gen Hosp, Dept Dermatol, Beijing 100012, Peoples R China.
   [Zhu, Guo-Jian] Taian Commun Hosp, Dept Gen Surg, Tai An 271000, Shandong, Peoples R China.
   [Liu, Meng] Tianjin Hexi Hosp, Dept Surg, Tianjin 300202, Tianjin, Peoples R China.
   [Shi, Shao-Hui] China Med Univ, Aviat Gen Hosp, Dept Orthopaed Surg, Beijing 100012, Peoples R China.
   [Ren, Xiao-Dong] Wanquanqu Zhongyi Hosp, Dept Surg, Zhangjiakou 076250, Hebei, Peoples R China.
   [Hao, Ya-Guang] China Med Univ, Aviat Gen Hosp, Dept Med Adm, Beijing 100012, Peoples R China.
   [Gao, Rong-Ding] China Med Univ, Aviat Gen Hosp, Dept Gen Surg, Beijing 100012, Peoples R China.
C3 China Medical University; China Medical University; China Medical
   University; China Medical University
RP Ren, SY (通讯作者)，China Med Univ, Dept Gen Surg & Vasc Surg, Aviat Gen Hosp, 2 Beiyuan Rd, Beijing 100012, Peoples R China.
EM rens66@126.com
RI Liu, Menghui/GWZ-2494-2022
CR Andrade SM, 2016, REV GAUCHA ENFERM, V37, DOI DOI 10.2337/DC10-0393
   Anselmo DS, 2018, WOUNDS, V30, P57
   Athanerey A, 2017, J TISSUE VIABILITY, V26, P216, DOI 10.1016/j.jtv.2017.06.001
   Bianchi C, 2019, INT WOUND J, V16, P761, DOI 10.1111/iwj.13094
   Bianchi C, 2018, INT WOUND J, V15, P114, DOI 10.1111/iwj.12843
   Bianchi L, 2002, J EUR ACAD DERMATOL, V16, P595, DOI 10.1046/j.1468-3083.2002.00526.x
   Bush R, 2017, PHLEBOLOGY, V32, P3, DOI 10.1177/0268355517692221
   Cervelli V, 2013, BIOMED RES INT, V2013, DOI 10.1155/2013/434191
   Cervelli V, 2011, STEM CELL RES, V6, P103, DOI 10.1016/j.scr.2010.11.003
   Conte MS, 2019, EUR J VASC ENDOVASC, V58, pS1, DOI 10.1016/j.ejvs.2019.05.006
   Davies Patricia, 2004, Prof Nurse, V19, P34
   De Angelis B, 2018, INT WOUND J, V15, P695, DOI 10.1111/iwj.12912
   De Angelis B, 2013, J TISSUE ENG, V4, DOI 10.1177/2041731413502663
   De T, 2019, J CLIN MED, V8, DOI 10.3390/jcm8091473
   Desman E, 2015, OSTOMY WOUND MANAG, V61, P16
   Elbarbary AH, 2020, INT WOUND J, V17, P992, DOI 10.1111/iwj.13361
   Farivar BS, 2019, J VASC SURG-VENOUS L, V7, P228, DOI 10.1016/j.jvsv.2018.09.016
   Fox JD, 2016, WOUNDS, V28, P109
   Garoufalis M, 2018, J AM PODIAT MED ASSN, V108, P84, DOI 10.7547/17-039
   Gentile P, 2020, BIOMED RES INT, V2020, DOI 10.1155/2020/7397162
   Gentile P, 2020, INT J MOL SCI, V21, DOI 10.3390/ijms21020431
   Gentile P, 2019, INT J MOL SCI, V20, DOI 10.3390/ijms20215471
   Gentile P, 2019, INT J MOL SCI, V20, DOI 10.3390/ijms20143446
   Gentile P, 2019, J CLIN MED, V8, DOI 10.3390/jcm8060855
   Gentile P, 2018, METHODS MOL BIOL, V1773, P107, DOI 10.1007/978-1-4939-7799-4_9
   Gentile Pietro, 2017, Stem Cell Investig, V4, P58, DOI [10.21037/sci.2017.06.04, 10.21037/sci.2017.06.04]
   Gentile P, 2017, STEM CELLS, V35, P117, DOI 10.1002/stem.2498
   Gentile P, 2013, SURG INNOV, V20, pNP12, DOI 10.1177/1553350611421022
   George R, 2014, EUR J VASC ENDOVASC, V48, P330, DOI 10.1016/j.ejvs.2014.04.031
   Gethin G, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008599.pub2
   Gohel MS, 2018, NEW ENGL J MED, V378, P2105, DOI 10.1056/NEJMoa1801214
   Hall Lucy, 2019, Br J Community Nurs, V24, pS24, DOI [10.12968/bjcn.2019.24.sup6.s24, 10.12968/bjcn.2019.24.Sup6.S24]
   Harding K, 2013, INT WOUND J, V10, P132, DOI 10.1111/iwj.12053
   Harlander-Locke M, 2012, J VASC SURG, V55, P446, DOI 10.1016/j.jvs.2011.08.009
   Hermans Michel H, 2007, Adv Skin Wound Care, V20, P166, DOI 10.1097/01.ASW.0000262712.05035.61
   Hesseler MJ, 2019, J AM ACAD DERMATOL, V81, P834, DOI 10.1016/j.jaad.2019.04.037
   Holland LC, 2015, INT J SURG, V20, P17, DOI 10.1016/j.ijsu.2015.05.048
   Jankunas V, 2007, WOUNDS, V19, P128
   Jiménez F, 2012, WOUND REPAIR REGEN, V20, P806, DOI 10.1111/j.1524-475X.2012.00846.x
   Jones JE, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001737.pub4
   Martinez-Zapata MJ, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006899.pub3
   Kaufman H, 2018, J WOUND CARE, V27, P426, DOI 10.12968/jowc.2018.27.7.426
   Kavala Ali Aycan, 2018, Arch Med Sci Atheroscler Dis, V3, pe156, DOI [10.5114/amsad.2018.81000, 10.5114/amsad.2018.81000]
   Kheirelseid EAH, 2016, SURG-J R COLL SURG E, V14, P219, DOI 10.1016/j.surge.2016.03.007
   Kogan S, 2018, WOUNDS, V30, P168
   Konstantinow A, 2017, J EUR ACAD DERMATOL, V31, P2104, DOI 10.1111/jdv.14489
   Larsen L, 2018, J TISSUE ENG REGEN M, V12, P186, DOI 10.1002/term.2390
   Lawrence PF, 2020, J VASC SURG-VENOUS L, V8, P601, DOI 10.1016/j.jvsv.2019.09.016
   Lectercq A, 2016, ANN DERMATOL VENER, V143, P3, DOI 10.1016/j.annder.2015.06.022
   Leong S, 2020, INT WOUND J, V17, P716, DOI 10.1111/iwj.13291
   Li X, 2018, ANN VASC SURG, V49, P75, DOI 10.1016/j.avsg.2018.01.004
   Li X, 2017, ANN VASC SURG, V45, P160, DOI 10.1016/j.avsg.2017.06.055
   Lim R, 2017, STEM CELL TRANSL MED, V6, P1767, DOI 10.1002/sctm.16-0447
   Lin F, 2015, INT SURG, V100, P185, DOI 10.9738/INTSURG-D-14-00084.1
   Lullove EJ, 2017, WOUNDS, V29, P346
   Malek Antoine, 2011, J Stem Cells, V6, P75
   Marston WA, 2017, J VASC SURG-VENOUS L, V5, P525, DOI 10.1016/j.jvsv.2017.02.007
   Martínez ML, 2016, J AM ACAD DERMATOL, V75, P1007, DOI 10.1016/j.jaad.2016.02.1161
   Martínez MLM, 2017, ACTAS DERMO-SIFILOGR, V108, P524, DOI [10.1016/j.adengl.2017.05.016, 10.1016/j.ad.2017.02.013]
   Maxson S, 2012, STEM CELL TRANSL MED, V1, P142, DOI 10.5966/sctm.2011-0018
   Mayer A, 2014, J TISSUE VIABILITY, V23, P94, DOI 10.1016/j.jtv.2014.08.001
   Medical Advisory Secretariat, 2006, Ont Health Technol Assess Ser, V6, P1
   Milek T, 2019, ADV EXP MED BIOL, V1176, P109, DOI 10.1007/5584_2019_388
   Miranda Edward P, 2016, Eplasty, V16, pe26
   Mosti G, 2015, J WOUND CARE, V24, P121, DOI 10.12968/jowc.2015.24.3.121
   Mosti G, 2013, PHLEBOLOGY, V28, P79, DOI 10.1177/0268355513477015
   Murphy EC, 2019, J AM ACAD DERMATOL, V81, P1379, DOI 10.1016/j.jaad.2019.05.030
   Nicolaides AN, 2020, ADV THER, V37, P1, DOI 10.1007/s12325-019-01218-8
   Nicolaides AN, 2020, ADV THER, V37, P19, DOI 10.1007/s12325-020-01219-y
   O'Meara S, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003557.pub5
   O'Meara S, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009907.pub2
   O'Meara S, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD000265.pub3
   Pearce FB, 2017, J WOUND CARE, V26, pS36, DOI 10.12968/jowc.2017.26.Sup1.S36
   Prakash TV, 2016, CUREUS J MED SCIENCE, V8, DOI 10.7759/cureus.516
   Pugliese DJ, 2016, DRUG AGING, V33, P87, DOI 10.1007/s40266-016-0343-8
   Rollo JC, 2017, J VASC SURG-VENOUS L, V5, P789, DOI 10.1016/j.jvsv.2017.05.020
   Sadler GM, 2012, ARCH DERMATOL RES, V304, P487, DOI 10.1007/s00403-011-1201-5
   Salgado RM, 2017, J TISSUE VIABILITY, V26, P131, DOI 10.1016/j.jtv.2017.01.004
   Scioli MG, 2017, J TISSUE ENG REGEN M, V11, P2398, DOI 10.1002/term.2139
   Serena TE, 2015, J WOUND CARE, V24, P530, DOI 10.12968/jowc.2015.24.11.530
   Serena TE, 2014, WOUND REPAIR REGEN, V22, P688, DOI 10.1111/wrr.12227
   Sermsathanasawadi N, 2019, J VASC SURG-VENOUS L, V7, P441, DOI 10.1016/j.jvsv.2018.10.021
   Serra R, 2015, INT WOUND J, V12, P179, DOI 10.1111/iwj.12077
   Siadat AH, 2019, ADV WOUND CARE, V8, P160, DOI 10.1089/wound.2018.0866
   Sîrbi AG, 2015, ROM J MORPHOL EMBRYO, V56, P309
   Snyder RJ, 2015, OSTOMY WOUND MANAG, V61, P40
   Sun Y, 2017, INT J SURG, V42, P49, DOI 10.1016/j.ijsu.2017.04.023
   Suzuki H, 2016, TRANSPL P, V48, P982, DOI 10.1016/j.transproceed.2015.12.107
   Thomas B, 2017, J VASC SURG-VENOUS L, V5, P844, DOI 10.1016/j.jvsv.2017.04.019
   Tian Y, 2018, BMC SURG, V18, DOI 10.1186/s12893-018-0411-6
   Todd Marie, 2019, Br J Nurs, V28, pS32, DOI [10.12968/bjon.2019.28.12.s32, 10.12968/bjon.2019.28.12.S32]
   Towler MA, 2018, CLIN PODIATR MED SUR, V35, P357, DOI 10.1016/j.cpm.2018.02.006
   WARD DJ, 1984, BRIT J PLAST SURG, V37, P191, DOI 10.1016/0007-1226(84)90009-2
   Weller CD, 2019, INT WOUND J, V16, P788, DOI 10.1111/iwj.13098
   Wen Huangding, 2015, Zhonghua Shao Shang Za Zhi, V31, P86
   Wong IKY, 2012, J VASC SURG, V55, P1376, DOI 10.1016/j.jvs.2011.12.019
   Wu CC, 2015, ADV SKIN WOUND CARE, V28, P21, DOI 10.1097/01.ASW.0000459038.81701.fb
   Yang CK, 2015, J VASC SURG, V61, P995, DOI 10.1016/j.jvs.2014.11.076
   Ye JN, 2015, MEDICINE, V94, DOI 10.1097/MD.0000000000000426
   Zimanova J, 2011, BRATISL MED J, V112, P447
   Zollino I, 2019, CYTOTHERAPY, V21, P200, DOI 10.1016/j.jcyt.2018.10.012
   Zollino I, 2017, PHLEBOLOGY, V32, P160, DOI 10.1177/0268355516641546
   Zou P, 2020, WORLD NEUROSURG, V138, P201, DOI 10.1016/j.wneu.2020.03.035
NR 103
TC 33
Z9 40
U1 0
U2 24
PU BAISHIDENG PUBLISHING GROUP INC
PI PLEASANTON
PA 7041 Koll Center Parkway, Suite 160, PLEASANTON, CA, UNITED STATES
SN 2307-8960
J9 WORLD J CLIN CASES
JI World J. Clin. Cases
PD NOV 6
PY 2020
VL 8
IS 21
DI 10.12998/wjcc.v8.i21.5070
PG 17
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA PA5RI
UT WOS:000595692200001
PM 33269244
OA Green Accepted, gold
DA 2026-07-24
ER

PT J
AU Borys, S
   Hohendorff, J
   Koblik, T
   Witek, P
   Ludwig-Slomczynska, AH
   Frankfurter, C
   Kiec-Wilk, B
   Malecki, MT
AF Borys, S.
   Hohendorff, J.
   Koblik, T.
   Witek, P.
   Ludwig-Slomczynska, A. H.
   Frankfurter, C.
   Kiec-Wilk, B.
   Malecki, M. T.
TI Negative-pressure wound therapy for management of chronic neuropathic
   noninfected diabetic foot ulcerations - short-term efficacy and
   long-term outcomes
SO ENDOCRINE
LA English
DT Article
DE Negative-pressure wound therapy; Diabetic foot syndrome; Type 2 diabetes
ID IWGDF GUIDANCE; ULCERS; AMPUTATION; PREVENTION; MULTICENTER; DISEASE
AB PurposeNegative pressure wound therapy (NPWT) is an adjunct method used in the treatment of diabetic foot ulceration (DFU). Real world data on its effectiveness and safety is scarce. In this prospective observational study, we assessed the short-term efficacy, safety, and long-term outcomes of NPWT in patients with type 2 diabetes (T2DM) and neuropathic, noninfected DFUs.MethodsBased on wound characteristics, mainly area (>1 vs. 1cm(2)), 75 patients with DFUs treated in an outpatient clinic were assigned to NPWT (n=53) or standard therapy (n=22). Wound area reduction was evaluated after 81 days. Long-term outcomes assessed included complete ulceration closure and recurrence rate.ResultsPatients assigned to NPWT were characterized by greater wound area (15.7 vs. 2.9cm(2)). Reduction in wound area was found in both the NPWT (-1.1cm(2), -10.2%, p=0.0001) and comparator group (-0.3cm(2), -18.0%, p=0.0038). No serious adverse events related to NPWT were noted. Within 1 year, 55.1% (27/49) of DFUs were closed in the NPWT group and 73.7% (14/19) in the comparator group (p=0.15). In the logistic regression, wound duration and smaller initial area, but not treatment mode, were associated with closure. One-year follow-up after DFU resolution revealed an 30.0% recurrence rate in both groups (p=0.88).ConclusionsNPWT is a safe treatment for neuropathic, nonischemic, and noninfected DFU in patients with T2DM, although this observational study did not prove its effectiveness over standard therapy. Additionally, we report a high rate of both closure and recurrence of ulcers, the latter irrespective of initial ulcer area.
C1 [Borys, S.; Hohendorff, J.; Koblik, T.; Witek, P.; Kiec-Wilk, B.; Malecki, M. T.] Univ Hosp Krakow, Dept Metab Dis, Krakow, Poland.
   [Borys, S.; Hohendorff, J.; Witek, P.; Kiec-Wilk, B.; Malecki, M. T.] Jagiellonian Univ, Dept Metab Dis, Med Coll, Krakow, Poland.
   [Ludwig-Slomczynska, A. H.] Jagiellonian Univ, Ctr Med Genom OMICRON, Med Coll, Krakow, Poland.
   [Frankfurter, C.] Univ Toronto, Fac Med, Toronto, ON, Canada.
C3 Jagiellonian University; Collegium Medicum Jagiellonian University;
   Jagiellonian University; Collegium Medicum Jagiellonian University;
   Jagiellonian University; Collegium Medicum Jagiellonian University;
   University of Toronto
RP Malecki, MT (通讯作者)，Univ Hosp Krakow, Dept Metab Dis, Krakow, Poland.; Malecki, MT (通讯作者)，Jagiellonian Univ, Dept Metab Dis, Med Coll, Krakow, Poland.
EM malecki_malecki@yahoo.com
RI ; Hohendorff, Jerzy/U-1857-2018; Witek, Przemysław/AGX-0421-2022
OI Ludwig-Słomczyńska, Agnieszka H/0000-0002-0548-4767; Hohendorff,
   Jerzy/0000-0003-1153-8669; 
FU National Science Centre in Poland through the Opus Grant "Assessment of
   molecular mechanisms of negative pressure wound therapy in the treatment
   of neuropathic ulceration in diabetic foot syndrome"
   [2013/11/B/NZ5/03298]; European Union (7th Framework Programme)
   [FP7-REGPOT-2011-1, 286038]
FX The study was funded by the National Science Centre in Poland through
   the Opus Grant "Assessment of molecular mechanisms of negative pressure
   wound therapy in the treatment of neuropathic ulceration in diabetic
   foot syndrome" to MTM (Nr 2013/11/B/NZ5/03298). The Omicron laboratory
   (where the microarray experiments were performed) was funded by the
   European Union (7th Framework Programme, Call number FP7-REGPOT-2011-1,
   Grant number 286038).
CR Apelqvist J, 2000, DIABETES-METAB RES, V16, pS75, DOI 10.1002/1520-7560(200009/10)16:1+<::AID-DMRR139>3.3.CO;2-#
   Apelqvist Jan, 2017, J Wound Care, V26, pS1, DOI [10.12968/jowc.2017.26.sup3.s1, 10.12968/jowc.2017.26.Sup3.S1]
   Armstrong DG, 2017, NEW ENGL J MED, V376, P2367, DOI 10.1056/NEJMra1615439
   Armstrong DG, 2013, J AM PODIAT MED ASSN, V103, P161, DOI 10.7547/1030161
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Armstrong DG, 2001, DIABETES CARE, V24, P1019, DOI 10.2337/diacare.24.6.1019
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Borys S, 2017, DIABETOLOGIA, V60, pS470
   Boulton AJM, 2008, DIABETES-METAB RES, V24, pS3, DOI 10.1002/dmrr.833
   Bus SA, 2016, DIABETES-METAB RES, V32, P25, DOI 10.1002/dmrr.2697
   Fesseha BK, 2018, DIABETES CARE, V41, P1478, DOI 10.2337/dc17-1683
   Fife CE, 2010, WOUND REPAIR REGEN, V18, P154, DOI 10.1111/j.1524-475X.2010.00571.x
   Hasan MY, 2015, DIABET FOOT ANKLE, V6, DOI 10.3402/dfa.v6.27618
   He Y, 2017, EUR J ENDOCRINOL, V177, P41, DOI 10.1530/EJE-17-0070
   Hoffmann M, 2015, DIABETES VASC DIS RE, V12, P265, DOI 10.1177/1479164115579005
   Holman N, 2012, DIABETOLOGIA, V55, P1919, DOI 10.1007/s00125-012-2468-6
   Iversen MM, 2009, DIABETES CARE, V32, P2193, DOI 10.2337/dc09-0651
   Lincoln NB, 2008, DIABETOLOGIA, V51, P1954, DOI 10.1007/s00125-008-1110-0
   MUELLER MJ, 1989, DIABETES CARE, V12, P384, DOI 10.2337/diacare.12.6.384
   Muller IS, 2002, DIABETES CARE, V25, P570, DOI 10.2337/diacare.25.3.570
   Prompers L, 2008, DIABETOLOGIA, V51, P747, DOI 10.1007/s00125-008-0940-0
   Prompers L, 2007, DIABETOLOGIA, V50, P18, DOI 10.1007/s00125-006-0491-1
   Schaper NC, 2017, DIABETES RES CLIN PR, V124, P84, DOI 10.1016/j.diabres.2016.12.007
   Skrepnek GH, 2017, DIABETES CARE, V40, P936, DOI 10.2337/dc16-2189
   Tamir E, 2018, ADV SKIN WOUND CARE, V31, P365, DOI 10.1097/01.ASW.0000531352.93490.24
   Walsh JW, 2016, DIABETIC MED, V33, P1493, DOI 10.1111/dme.13054
   Wright AK, 2017, DIABETES CARE, V40, P338, DOI 10.2337/dc16-1616
NR 27
TC 29
Z9 44
U1 0
U2 21
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1355-008X
EI 1559-0100
J9 ENDOCRINE
JI Endocrine
PD DEC
PY 2018
VL 62
IS 3
BP 611
EP 616
DI 10.1007/s12020-018-1707-0
PG 6
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA HC6ZS
UT WOS:000451950800014
PM 30099674
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Wells, CI
   Ratnayake, CBB
   Perrin, J
   Pandanaboyana, S
AF Wells, Cameron, I
   Ratnayake, Chathura B. B.
   Perrin, Jenni
   Pandanaboyana, Sanjay
TI Prophylactic Negative Pressure Wound Therapy in Closed Abdominal
   Incisions: A Meta-analysis of Randomised Controlled Trials
SO WORLD JOURNAL OF SURGERY
LA English
DT Review
ID SURGICAL SITE INFECTION; COLORECTAL SURGERY; CARE; PREVENTION;
   MANAGEMENT; CLOSURE; COMPLICATIONS; LAPAROTOMY; IMPACT; RISK
AB Introduction Negative pressure wound therapy (NPWT) may prevent subcutaneous fluid accumulation in a closed wound and subsequently reduce surgical site infections (SSI). This meta-analysis aimed to determine the effect of prophylactic NPWT on SSI incidence following abdominal surgery. Methods A systematic search of MEDLINE and EMBASE databases was performed using PRISMA methodology. All randomised trials reporting the use of NPWT in closed abdominal incisions were included, regardless of the type of operation. The primary outcome measure was the incidence of SSI, stratified by superficial and deep and organ/space infections. Secondary outcomes were wound dehiscence and length of hospital stay. Results Ten randomised trials met the inclusion criteria (five Caesarean, five midline laparotomy). The use of NPWT reduced overall SSI (11.6% vs. 16.7%, RR 0.67, 95% CI 0.48-0.95, p = 0.02). The rate of superficial SSI rate was also reduced (6.3% vs. 11.3%, RR 0.57, 95% CI 0.35-0.94, p = 0.03). There was no effect on deep or organ/space SSI (3.2% vs. 4.2%, RR 0.77, 95% CI 0.51-1.18, p = 0.23), wound dehiscence (9.7% vs. 10.9%, RR 0.92, 95% CI 0.69-1.21, p = 0.54), or length of hospital stay (MD 0.06 days, 95% CI-0.11 to 0.23, p = 0.51). Conclusions Prophylactic use of NPWT may reduce the incidence of superficial SSI in closed abdominal incisions but has no effect on deep or organ space SSI.
C1 [Wells, Cameron, I; Ratnayake, Chathura B. B.; Perrin, Jenni; Pandanaboyana, Sanjay] Univ Auckland, Fac Med & Hlth Sci, Dept Surg, Auckland, New Zealand.
   [Pandanaboyana, Sanjay] Newcastle Upon Tyne NHS Trust, Dept HPB & Transplant Surg, Freeman Hosp, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England.
C3 University of Auckland; Newcastle Upon Tyne Hospitals NHS Foundation
   Trust; Newcastle Freeman Hospital
RP Pandanaboyana, S (通讯作者)，Univ Auckland, Fac Med & Hlth Sci, Dept Surg, Auckland, New Zealand.; Pandanaboyana, S (通讯作者)，Newcastle Upon Tyne NHS Trust, Dept HPB & Transplant Surg, Freeman Hosp, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England.
EM sanjay.pandanaboyana@nuth.nhs.uk
RI ; Wells, Cameron/AFP-7151-2022; pandanaboyana, sanjay/U-2626-2019
OI Ratnayake, Bathiya/0000-0002-5188-9124; 
CR Alexander HC, 2018, HPB, V20, P786, DOI 10.1016/j.hpb.2018.03.004
   Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe288, DOI 10.1016/S1473-3099(16)30402-9
   Anderson DJ, 2014, INFECT CONT HOSP EP, V35, P605, DOI 10.1086/676022
   [Anonymous], BJOG
   [Anonymous], BR J SURG
   [Anonymous], J EVID BASED MED
   [Anonymous], ANN SURG
   [Anonymous], ANN SURG
   [Anonymous], BJOG
   Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
   Badia JM, 2017, J HOSP INFECT, V96, P1, DOI 10.1016/j.jhin.2017.03.004
   Brölmann FE, 2013, WOUND REPAIR REGEN, V21, P641, DOI 10.1111/wrr.12087
   Bruce J, 2001, J HOSP INFECT, V49, P99, DOI 10.1053/jhin.2001.1045
   Chaboyer W, 2014, HEALTHCARE, V2, P417, DOI 10.3390/healthcare2040417
   de Jonge SW, 2017, MEDICINE, V96, DOI 10.1097/MD.0000000000006903
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   DERSIMONIAN R, 1986, CONTROL CLIN TRIALS, V7, P177, DOI 10.1016/0197-2456(86)90046-2
   Egger M, 1997, BMJ-BRIT MED J, V315, P629, DOI 10.1136/bmj.315.7109.629
   Ge DM, 2018, ADV SKIN WOUND CARE, V31, P421, DOI 10.1097/01.ASW.0000542530.71686.5c
   Gillespie BM, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2015-010287
   Gunatilake RP, 2017, AJP REP, V7, pE151, DOI 10.1055/s-0037-1603956
   Heard C, 2017, J TISSUE VIABILITY, V26, P79, DOI 10.1016/j.jtv.2016.06.001
   Higgins JPT, 2011, BMJ-BRIT MED J, V343, DOI 10.1136/bmj.d5928
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Imamura K, 2016, J GASTROINTEST SURG, V20, P2083, DOI 10.1007/s11605-016-3283-z
   Ingargiola Michael J, 2013, Eplasty, V13, pe49
   Kang SI, 2018, SURGERY, V164, P939, DOI 10.1016/j.surg.2018.05.024
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Keenan JE, 2014, JAMA SURG, V149, P1045, DOI 10.1001/jamasurg.2014.346
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Kobayashi M, 2008, WORLD J SURG, V32, P1142, DOI 10.1007/s00268-008-9536-6
   Li PY, 2017, SCAND J SURG, V106, P189, DOI 10.1177/1457496916668681
   Liberati A., 2009, PLOS MED, V6, P1, DOI [10.1016/j.jclinepi.2009.06.006, DOI 10.1016/J.JCLINEPI.2009.06.006, 10.1371/journal.pmed.1000100]
   Malmsjo Malin, 2014, Eplasty, V14, pe15
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Mihaljevic AL, 2015, TRIALS, V16, DOI 10.1186/s13063-015-0995-4
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Okubo S, 2018, SURGERY, V164, P251, DOI 10.1016/j.surg.2018.04.002
   Peinemann F, 2008, BMC MED RES METHODOL, V8, DOI 10.1186/1471-2288-8-4
   Pellino G, 2015, UPDATES SURG, V67, P235, DOI 10.1007/s13304-015-0298-z
   Ruhstaller K, 2017, AM J PERINAT, V34, P1125, DOI 10.1055/s-0037-1604161
   Sahebally SM, 2018, JAMA SURG, V153, DOI 10.1001/jamasurg.2018.3467
   Sandy-Hodgetts K, 2017, J WOUND CARE, V26, pS23, DOI 10.12968/jowc.2017.26.Sup2.S23
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Schulz KF, 2011, INT J SURG, V9, P672, DOI 10.1016/j.ijsu.2011.09.004
   Schwarzer G., R NEWS, V7, P40
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Suh H, 2016, ANN PLAS SURG, V76, P717, DOI 10.1097/SAP.0000000000000231
   Suissa D, 2011, PLAST RECONSTR SURG, V128, p498E, DOI 10.1097/PRS.0b013e31822b675c
   Tanner J, 2015, SURGERY, V158, P66, DOI 10.1016/j.surg.2015.03.009
   Glasgow SC, 2013, DIS COLON RECTUM, V56, P1339, DOI 10.1097/DCR.0b013e3182a857eb
   Toh JWT, 2018, JAMA NETW OPEN, V1, DOI 10.1001/jamanetworkopen.2018.3226
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   Uchino M, 2016, DIGEST SURG, V33, P449, DOI 10.1159/000446550
   Venkat R, 2012, ANN SURG, V255, P1048, DOI 10.1097/SLA.0b013e318251ee09
   Wihbey KA, 2018, OBSTET GYNECOL, V132, P377, DOI [10.1097/AOG.0000000000002744, 10.1097/aog.0000000000002744]
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Willy C, 2016, INT WOUND J, V13, P35, DOI 10.1111/iwj.12659
   Witt-Majchrzak Anna, 2015, Pol Przegl Chir, V86, P456, DOI [10.2478/pjs-2014-0082, 10.2478/pjs-2014-0082]
NR 64
TC 37
Z9 42
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD NOV
PY 2019
VL 43
IS 11
BP 2779
EP 2788
DI 10.1007/s00268-019-05116-6
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA JB8SX
UT WOS:000488847800018
PM 31396673
DA 2026-07-24
ER

PT J
AU Svensson-Björk, R
   Zarrouk, M
   Asciutto, G
   Hasselmann, J
   Acosta, S
AF Svensson-Bjork, R.
   Zarrouk, M.
   Asciutto, G.
   Hasselmann, J.
   Acosta, S.
TI Meta-analysis of negative pressure wound therapy of closed groin
   incisions in arterial surgery
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Article; Proceedings Paper
CT 32nd Annual Meeting of the European-Society-for-Vascular-Surgery (ESVS)
CY SEP 22-28, 2018
CL Valencia, SPAIN
SP Europ Soc Vasc Surg
ID SURGICAL-SITE INFECTIONS; RISK; COMPLICATIONS; PREVENTION; DRESSINGS;
   TRIALS
AB Background: Surgical-site infection (SSI) after groin incisions for arterial surgery is common and may lead to amputation or death. Incisional negative pressure wound therapy (NPWT) dressings have been suggested to reduce SSIs. The aim of this systematic review with meta-analysis was to assess the effects of incisional NPWT on the incidence of SSI in closed groin incisions after arterial surgery.
   Methods: A study protocol for this systematic review of RCTs was published in Prospero (CRD42018090298) a priori, with predefined search, inclusion and exclusion criteria. The records generated by the systematic research were screened for relevance by title and abstract and in full text by two of the authors independently. The selected articles were rated for bias according to the Cochrane risk-of-bias tool.
   Results: Among 1567 records generated by the search, seven RCTs were identified, including 1049 incisions. Meta-analysis showed a reduction in SSI with incisional NPWT (odds ratio (OR) 0.35, 95 per cent c.i. 0.24 to 0.50; P < 0.001). The heterogeneity between the included studies was low (I-2 = 0 per cent). The quality of evidence was graded as moderate. Two studies had multiple domains in the Cochrane risk-of-bias tool rated as high risk of bias. A subgroup meta-analysis of three studies of lower limb revascularization procedures only (363 incisions) demonstrated a similar reduction in SSI (OR 0.37, 0.22 to 0.63; P < 0.001; I-2 = 0 per cent).
   Conclusion: Incisional NPWT after groin incisions for arterial surgery reduced the incidence of SSI compared with standard wound dressings. The risk of bias highlighted the need for a high-quality RCT with cost-effectiveness analysis.
C1 [Svensson-Bjork, R.; Zarrouk, M.; Asciutto, G.; Hasselmann, J.; Acosta, S.] Skane Univ Hosp, Vasc Ctr, Malmo, Sweden.
   [Svensson-Bjork, R.; Zarrouk, M.; Asciutto, G.; Hasselmann, J.; Acosta, S.] Lund Univ, Dept Clin Sci, Ruth Lundskogs Gata 10, S-20502 Malmo, Sweden.
C3 Lund University; Skane University Hospital; Lund University
RP Svensson-Björk, R (通讯作者)，Lund Univ, Dept Clin Sci, Ruth Lundskogs Gata 10, S-20502 Malmo, Sweden.
EM robert.svensson_bjork@med.lu.se
RI Hasselmann, Julien/C-1586-2015; Hasselmann, Julien/C-1586-2015; Acosta,
   Stefan/JAX-3225-2023
OI Hasselmann, Julien/0000-0003-4453-0292; Svensson-Björk,
   Robert/0000-0003-1907-9022; Acosta, Stefan/0000-0002-3225-0798
CR [Anonymous], 2009, BMJ-BRIT MED J, V21, P7, DOI [DOI 10.1136/bmj.b2535, 10.1371/journal.pmed.1000097, DOI 10.7326/0003-4819-151-4-200908180-00135]
   [Anonymous], 2016, Global Guidelines for the Prevention of Surgical Site Infection
   [Anonymous], 26 C EUR WOUND MAN A
   [Anonymous], sing the risk of bias of individual studies in systematic
   Borgquist O, 2010, ANN PLAS SURG, V64, P789, DOI 10.1097/SAP.0b013e3181ba578a
   Cassini A, 2016, PLOS MED, V13, DOI 10.1371/journal.pmed.1002150
   Coomer NM, 2016, AM J INFECT CONTROL, V44, P1326, DOI 10.1016/j.ajic.2016.03.025
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   Dell-Kuster S, 2018, BRIT J SURG, V105, P182, DOI 10.1002/bjs.10763
   DiMuzio P, 2017, J VASC SURG, V65, p133S, DOI 10.1016/j.jvs.2017.03.250
   Eisenhardt SU, 2012, J PLAST RECONSTR AES, V65, P640, DOI 10.1016/j.bjps.2011.11.037
   Engelhardt M, 2018, INT WOUND J, V15, P327, DOI 10.1111/iwj.12848
   Ge DM, 2018, ADV SKIN WOUND CARE, V31, P421, DOI 10.1097/01.ASW.0000542530.71686.5c
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Hasselmann J, 2015, Surgical Science, V06, P562, DOI [10.4236/ss.2015.612080, DOI 10.4236/SS.2015.612080]
   Hasselmann J, 2015, VASC ENDOVASC SURG, V49, P129, DOI 10.1177/1538574415600531
   Higgins JPT, 2003, BMJ-BRIT MED J, V327, P557, DOI 10.1136/bmj.327.7414.557
   Higgins JPT, 2002, STAT MED, V21, P1539, DOI 10.1016/j.bandl.2008.10.005
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Janczak D, 2017, ANN THORAC CARDIOVAS, V23, P135, DOI 10.5761/atcs.oa.16-00282
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Kuy S, 2014, ANN VASC SURG, V28, P53, DOI 10.1016/j.avsg.2013.08.002
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Loveluck John, 2016, Eplasty, V16, pe20
   Lundh A, 2012, COCHRANE DB SYST REV, DOI [10.1002/14651858.MR000033.pub2, 10.1002/14651858.MR000033.pub3]
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Sabat J, 2016, J VASC SURG, V63, p94S, DOI 10.1016/j.jvs.2016.03.099
   Semsarzadeh NN, 2015, PLAST RECONSTR SURG, V136, P592, DOI 10.1097/PRS.0000000000001519
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Swinnen J, 2010, ANN VASC SURG, V24, P336, DOI 10.1016/j.avsg.2009.07.020
   SZILAGYI DE, 1972, ANN SURG, V176, P321, DOI 10.1097/00000658-197209000-00008
   Turtiainen J, 2010, SCAND J SURG, V99, P167, DOI 10.1177/145749691009900312
   WILSON APR, 1986, LANCET, V1, P311
NR 36
TC 39
Z9 41
U1 0
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD MAR
PY 2019
VL 106
IS 4
BP 310
EP 318
DI 10.1002/bjs.11100
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA HM9KB
UT WOS:000459801800003
PM 30725478
OA Bronze
DA 2026-07-24
ER

PT J
AU Zhang, YX
   Guo, DZ
   Song, LZ
   Su, GW
   Lin, ZH
   Zhang, HL
   Wan, HF
   Zhang, WZQ
   Zou, Z
AF Zhang, Yixiao
   Guo, Dezhi
   Song, Lizhou
   Su, Guowei
   Lin, Zhiheng
   Zhang, Haoling
   Wan, Haifang
   Zhang, Wangzheqi
   Zou, Zui
TI Inflammation and wound healing: a comprehensive overview of mechanisms,
   therapeutic strategies, and translational perspectives
SO BIOMARKER RESEARCH
LA English
DT Review
DE Inflammatory response; Wound healing; Immune cells; Cytokines;
   Biomaterials; Negative pressure wound therapy; Regenerative medicine;
   Clinical translation
ID FOOT; KERATINOCYTES; MACROPHAGES; NEUTROPHILS; OUTCOMES; REPAIR
AB Wound healing is the dynamic biological process by which an organism restores homeostasis following injury and is characterized by a series of stages resulting in hemostasis, inflammatory response, proliferation, and tissue remodeling. As a consequence, the inflammatory response represents a key early step in this process and plays a central role in clearing necrotic debris and pathogens, as well as inducing reparative pathways. Mild to moderate inflammation induces angiogenesis, fibroblast activation, and extracellular matrix (ECM) remodeling, whereas chronic or excessive inflammation causes tissue damage, fibrosis, and chronic non-healing wounds. The current review systematically illustrates the contribution and dynamics of the inflammatory response underlying wound healing. These processes consist of immune cell polarization, regulation of cytokines and chemokines, and signaling network dynamics, hence emphasis is laid on the canonical mechanism for maintaining steady-state tissue restoration, namely, immune homeostasis. Moreover, this review examines the dynamic cross-talk of growth factors, ECM components, and angiogenesis in different healing phases. An overview of novel interventions is also included such as negative pressure wound therapy (NPWT), hyperbaric oxygen, exosome-based approaches, biomaterial-based approaches, nanohydrogel systems, and microneedle-facilitated delivery, with insights into mechanisms and translational progress. Critical clinical translation barriers, including wound heterogeneity, host-microbe cross-talk, and limitations of model extrapolation as well as the potential application of multi-omics integration and an interdisciplinary approach towards precision wound healing, are discussed. Overall, regulation of inflammation is the foundation for the whole wound healing cascade, and immune homeostasis is a key prerequisite for injury repair. Tailored therapeutic strategies might thus greatly enhance healing outcomes and clinical efficacy.
C1 [Zhang, Yixiao; Su, Guowei; Wan, Haifang] Zhejiang Hosp Integrated Tradit Chinese & Western, Dept Anesthesiol, Hangzhou 310003, Peoples R China.
   [Guo, Dezhi; Song, Lizhou; Zhang, Wangzheqi; Zou, Zui] Naval Med Univ, Changhai Hosp, Dept Anesthesiol, Shanghai 200433, Peoples R China.
   [Guo, Dezhi; Song, Lizhou; Zhang, Wangzheqi; Zou, Zui] Naval Med Univ, Sch Anesthesiol, Shanghai 200433, Peoples R China.
   [Lin, Zhiheng] Shanghai Univ Tradit Chinese Med, Longhua Hosp, Dept Gynecol, Shanghai 200032, Peoples R China.
   [Zhang, Haoling] Univ Sains Malaysia, Pusat Kanser Tun Abdullah Ahmad Badawi, Dept Biomed Sci, Kepala Batas Pulau Pinang 13200, Malaysia.
C3 Naval Medical University; Naval Medical University; Shanghai University
   of Traditional Chinese Medicine; Universiti Sains Malaysia
RP Wan, HF (通讯作者)，Zhejiang Hosp Integrated Tradit Chinese & Western, Dept Anesthesiol, Hangzhou 310003, Peoples R China.; Zhang, WZQ; Zou, Z (通讯作者)，Naval Med Univ, Changhai Hosp, Dept Anesthesiol, Shanghai 200433, Peoples R China.; Zhang, WZQ; Zou, Z (通讯作者)，Naval Med Univ, Sch Anesthesiol, Shanghai 200433, Peoples R China.; Zhang, HL (通讯作者)，Univ Sains Malaysia, Pusat Kanser Tun Abdullah Ahmad Badawi, Dept Biomed Sci, Kepala Batas Pulau Pinang 13200, Malaysia.
EM zhanghaolingedu@163.com; yb2218204@zju.edu.cn; zwzq001031@smmu.edu.cn;
   zouzui@smmu.edu.cn
RI Zhang, Wangzheqi/OOL-4821-2025
FU National Natural Science Foundation of China [82572494]
FX This study was funded The National Natural Science Foundation of China
   (Grant No. 82572494).
CR Abdulazeem L, 2022, Arch Razi Inst, V77, P747, DOI [10.22092/ari.2022.356981.1954, 10.22092/ARI.2022.356981.1954]
   Adib Y, 2025, CELLS-BASEL, V14, DOI 10.3390/cells14120909
   Al Kadi M, 2025, LIFE SCI ALLIANCE, V8, DOI 10.26508/lsa.202403008
   Almet AA, 2025, J INVEST DERMATOL, V145, DOI 10.1016/j.jid.2024.06.1281
   Amuso VM, 2025, J INVEST DERMATOL, V145, DOI [10.1016/j.jid.2024.10.609, 10.1016/j.jid.2024.10.609]
   Belakova B, 2025, CELLS-BASEL, V14, DOI 10.3390/cells14110806
   Bitterman D, 2024, ARCH DERMATOL RES, V316, DOI 10.1007/s00403-024-03352-y
   Boots EA, 2022, BRAIN BEHAV IMMUN, V103, P163, DOI 10.1016/j.bbi.2022.04.014
   Brown DL, 1997, SURGERY, V121, P372, DOI 10.1016/S0039-6060(97)90306-8
   Butenko S, 2024, NAT COMMUN, V15, DOI 10.1038/s41467-024-50072-y
   Campbell A, 2024, WOUND REPAIR REGEN, V32, P811, DOI 10.1111/wrr.13184
   Cao DX, 2024, INFLAMM BOWEL DIS, V31, P321, DOI 10.1093/ibd/izae202
   Carballo-Pedrares N, 2026, DRUG DELIV TRANSL RE, V16, P1685, DOI 10.1007/s13346-025-02033-1
   Chandran S, 2020, FRONT IMMUNOL, V11, DOI [10.1101/2019.12.23.887109, 10.3389/fimmu.2020.00787]
   Chang R, 2023, INT J BIOL MACROMOL, V226, P870, DOI 10.1016/j.ijbiomac.2022.12.116
   Chen C, 2025, J INVEST DERMATOL, V145, DOI 10.1016/j.jid.2024.05.007
   Chen K, 2021, NAT COMMUN, V12, DOI 10.1038/s41467-021-25410-z
   Chen SW, 2024, ACS BIOMATER SCI ENG, V10, P7206, DOI 10.1021/acsbiomaterials.4c01262
   Chen XS, 2023, BIOMATER ADV, V147, DOI 10.1016/j.bioadv.2023.213302
   Chen YH, 2025, INT J NANOMED, V20, P1679, DOI 10.2147/IJN.S505918
   Chen ZX, 2026, CELL REP, V45, DOI 10.1016/j.celrep.2025.116829
   Cheng YH, 2022, PLOS ONE, V17, DOI 10.1371/journal.pone.0275748
   Chieosilapatham P, 2020, J DERMATOL SCI, V99, P158, DOI 10.1016/j.jdermsci.2020.07.003
   Choi D, 2025, J INVEST DERMATOL, V145, P678, DOI 10.1016/j.jid.2024.07.017
   Crainiciuc G, 2022, NATURE, V601, P415, DOI 10.1038/s41586-021-04263-y
   Cui ZX, 2024, J CONTROL RELEASE, V366, P297, DOI 10.1016/j.jconrel.2023.12.046
   Dadras M, 2022, PLAST RECONSTR SURG, V149, DOI 10.1097/PRS.0000000000009023
   Dallmann AC, 2025, ADV WOUND CARE, V14, P645, DOI 10.1089/wound.2024.0095
   Das A, 2018, SCI REP-UK, V8, DOI 10.1038/s41598-018-19879-w
   Denorme F, 2020, BLOOD, V135, P429, DOI 10.1182/blood.2019002124
   Ding YH, 2024, CELL TISSUE BANK, V26, DOI 10.1007/s10561-024-10150-3
   Dong XY, 2025, BIOACT MATER, V47, P1, DOI 10.1016/j.bioactmat.2024.12.030
   Du KH, 2026, ACTA BIOMATER, V215, P21, DOI 10.1016/j.actbio.2026.03.039
   Duke KS, 2017, PART FIBRE TOXICOL, V14, DOI 10.1186/s12989-017-0207-3
   Engel A, 2024, RNA BIOL, V21, P31, DOI 10.1080/15476286.2024.2361571
   Feng X, 2023, EXP DERMATOL, V32, P403, DOI 10.1111/exd.14718
   Fraire-Zamora JJ, 2018, WOUND REPAIR REGEN, V26, P102, DOI 10.1111/wrr.12617
   Frear CC, 2021, SCI REP-UK, V11, DOI 10.1038/s41598-021-95893-9
   Fu Y, 2023, THERANOSTICS, V13, P2757, DOI 10.7150/thno.81406
   Geng K, 2023, CELL BIOL TOXICOL, V39, P1577, DOI 10.1007/s10565-022-09748-8
   Gong YT, 2025, J STEROID BIOCHEM, V252, DOI 10.1016/j.jsbmb.2025.106799
   Guo CY, 2025, MATRIX BIOL, V136, P9, DOI 10.1016/j.matbio.2024.12.011
   Hady TF, 2021, J TISSUE ENG REGEN M, V15, P24, DOI 10.1002/term.3160
   Hassanshahi A, 2022, CELLS-BASEL, V11, DOI 10.3390/cells11192953
   Henn D, 2023, NAT COMMUN, V14, DOI 10.1038/s41467-023-40519-z
   Holsapple JS, 2021, INT J MOL SCI, V22, DOI 10.3390/ijms22157844
   Honda A, 2025, EMBO REP, V26, P3679, DOI 10.1038/s44319-025-00496-4
   Horckmans M, 2017, EUR HEART J, V38, P187, DOI 10.1093/eurheartj/ehw002
   Hossam E, 2022, ANN VASC SURG, V82, P165, DOI 10.1016/j.avsg.2021.10.061
   Hua YJ, 2023, NAT COMMUN, V14, DOI 10.1038/s41467-023-43421-w
   Huang CJ, 2023, MOL MED REP, V28, DOI 10.3892/mmr.2023.13042
   Huang YX, 2025, SCI REP-UK, V15, DOI 10.1038/s41598-025-90643-7
   Huang ZL, 2026, PHYTOMEDICINE, V155, DOI 10.1016/j.phymed.2026.158124
   Inatomi Y, 2019, J WOUND CARE, V28, pS16, DOI 10.12968/jowc.2019.28.Sup8.S16
   Ismahil MA, 2025, CIRCULATION, V151, P1712, DOI 10.1161/CIRCULATIONAHA.124.071772
   Jia QY, 2023, FRONT IMMUNOL, V14, DOI 10.3389/fimmu.2023.1214757
   Jiang WL, 2025, NAT COMMUN, V16, DOI [10.1038/s41467-025-58906-z, 10.1038/s41467-025-58906-z]
   Jin EY, 2025, J NANOBIOTECHNOL, V23, DOI 10.1186/s12951-025-03138-y
   Junak M, 2025, WOUND REPAIR REGEN, V33, DOI 10.1111/wrr.70061
   Kaiser R, 2024, BLOOD, V144, P2546, DOI 10.1182/blood.2024025476
   Kalan LR, 2019, CELL HOST MICROBE, V25, P641, DOI 10.1016/j.chom.2019.03.006
   Kallenbach JG, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-07124-4
   Kartika RW, 2021, ACTA MED INDONES, V53, P268
   Kim H, 2023, BIOMATERIALS, V292, DOI 10.1016/j.biomaterials.2022.121941
   Kim PJ, 2015, PLAST RECONSTR SURG, V136, p657E, DOI 10.1097/PRS.0000000000001709
   Kimball AS, 2017, DIABETES, V66, P2459, DOI 10.2337/db17-0194
   Kimball AS, 2017, FRONT IMMUNOL, V8, DOI 10.3389/fimmu.2017.00635
   Kirketerp-Moller K, 2008, J CLIN MICROBIOL, V46, P2717, DOI 10.1128/JCM.00501-08
   Kirsner R, 2019, WOUND REPAIR REGEN, V27, P519, DOI 10.1111/wrr.12727
   Lauder SN, 2017, SCI SIGNAL, V10, DOI 10.1126/scisignal.aan2787
   Lawler W, 2025, J IMMUNOL, V214, P153, DOI [10.1093/jimmun/vkae011, 10.1093/jimmun/vkae011]
   Lee CR, 2023, TISSUE ENG REGEN MED, V20, P59, DOI 10.1007/s13770-022-00511-y
   Lee JH, 2023, INT J MOL SCI, V24, DOI 10.3390/ijms241310434
   Lee SH, 2025, INVEST OPHTH VIS SCI, V66, DOI 10.1167/iovs.66.6.35
   Li DQ, 2021, J INVEST DERMATOL, V141, P659, DOI 10.1016/j.jid.2020.06.037
   Li ZW, 2017, J BIOMED NANOTECHNOL, V13, P17, DOI 10.1166/jbn.2017.2324
   Liao Y, 2024, LIFE SCI, V358, DOI 10.1016/j.lfs.2024.123176
   Liu HW, 2024, CYTOKINE, V181, DOI 10.1016/j.cyto.2024.156691
   Liu ML, 2024, ADV SCI, V11, DOI 10.1002/advs.202306602
   Liu XL, 2022, STEM CELLS INT, V2022, DOI 10.1155/2022/1252557
   Liu Z Y, 2022, Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi, V38, P462, DOI 10.3760/cma.j.cn501120-20201209-00523
   Liu Z, 2025, CELL STEM CELL, V32, P479, DOI 10.1016/j.stem.2024.11.013
   Lodge S, 2025, J PROTEOME RES, V24, P4191, DOI 10.1021/acs.jproteome.5c00300
   Loesche M, 2017, J INVEST DERMATOL, V137, P237, DOI 10.1016/j.jid.2016.08.009
   Löndahl M, 2011, DIABETIC MED, V28, P186, DOI 10.1111/j.1464-5491.2010.03185.x
   Lu H, 2016, MEDIAT INFLAMM, V2016, DOI 10.1155/2016/2174682
   Lu YZ, 2024, NATURE, V628, P604, DOI 10.1038/s41586-024-07237-y
   Luo YD, 2022, BIOMATER ADV, V141, DOI 10.1016/j.bioadv.2022.213096
   Lv DM, 2023, CELL REP MED, V4, DOI 10.1016/j.xcrm.2023.101129
   Lv ZM, 2020, J INVEST SURG, V33, P636, DOI 10.1080/08941939.2018.1536177
   Ma R, 2025, MATER TODAY BIO, V32, DOI 10.1016/j.mtbio.2025.101915
   Manosalva C, 2025, INT J MOL SCI, V26, DOI 10.3390/ijms26136508
   Maraux M, 2025, CELL DEATH DIS, V16, DOI 10.1038/s41419-025-07909-1
   Maschalidi S, 2022, NATURE, V606, P776, DOI 10.1038/s41586-022-04754-6
   Maus KD, 2023, SCI SIGNAL, V16, DOI 10.1126/scisignal.add6527
   Maus KD, 2022, J LIPID RES, V63, DOI 10.1016/j.jlr.2022.100187
   Meghnem D, 2022, FRONT IMMUNOL, V13, DOI 10.3389/fimmu.2022.886213
   Meng H, 2025, ADV HEALTHC MATER, V14, DOI 10.1002/adhm.202404966
   Michels A, 2016, J THROMB HAEMOST, V14, P2274, DOI 10.1111/jth.13493
   Milcheski DA, 2025, J PLAST RECONSTR AES, V100, P208, DOI 10.1016/j.bjps.2024.11.005
   Mitsui K, 2023, J NEUROINFLAMM, V20, DOI 10.1186/s12974-023-02795-w
   Mölzer C, 2019, J TISSUE ENG REGEN M, V13, P1507, DOI 10.1002/term.2853
   Moravvej H, 2016, J BURN CARE RES, V37, pE90, DOI 10.1097/BCR.0b013e31825aeac1
   Mori HM, 2016, BMC COMPLEM ALTERN M, V16, DOI 10.1186/s12906-016-1128-7
   Mu YJ, 2024, MOLECULES, V29, DOI 10.3390/molecules29174281
   Ni RH, 2023, INT J MOL SCI, V24, DOI 10.3390/ijms24098358
   Nikolic N, 2019, J IMMUNOL RES, V2019, DOI 10.1155/2019/5143635
   Nuutila K, 2025, INT WOUND J, V22, DOI 10.1111/iwj.70144
   Omeir K, 2025, WOUND REPAIR REGEN, V33, DOI 10.1111/wrr.70055
   Ortiz-Zuniga A, 2023, J CLIN MED, V12, DOI 10.3390/jcm12175608
   Ou SJ, 2023, PEERJ, V11, DOI 10.7717/peerj.15894
   Pallin JA, 2023, BMC HEALTH SERV RES, V23, DOI 10.1186/s12913-023-10144-z
   Pang T, 2025, SCI REP-UK, V15, DOI 10.1038/s41598-025-03086-5
   Park JH, 2025, INT IMMUNOPHARMACOL, V159, DOI 10.1016/j.intimp.2025.114860
   Patsalos A, 2024, J CLIN INVEST, V134, DOI 10.1172/JCI173858
   Patsalos A, 2021, J EXP MED, V219, DOI 10.1084/jem.20210420
   Peña LT, 2025, SCI REP-UK, V15, DOI 10.1038/s41598-025-04710-0
   Prabahar A, 2025, PLOS COMPUT BIOL, V21, DOI 10.1371/journal.pcbi.1012997
   Qin ST, 2025, INFLAMMATION, V48, P633, DOI 10.1007/s10753-024-02073-8
   Radovic K, 2022, ACTA ODONTOL SCAND, V80, P9, DOI 10.1080/00016357.2021.1930149
   Rahaman MS, 2024, BIOMATERIALS, V311, DOI 10.1016/j.biomaterials.2024.122698
   Rahmani W, 2018, J INVEST DERMATOL, V138, P2111, DOI 10.1016/j.jid.2018.04.010
   Rajic J, 2025, INT J MOL SCI, V26, DOI 10.3390/ijms26031265
   Rembe JD, 2025, J TRANSL MED, V23, DOI [10.1186/s12967-025-06417-2, 10.1186/s12967-025-06417-2]
   Rognoni E, 2018, MOL SYST BIOL, V14, DOI 10.15252/msb.20178174
   Sailer M, 2025, J FOOT ANKLE RES, V18, DOI 10.1002/jfa2.70024
   Sangiovanni E, 2019, PHYTOTHER RES, V33, P2083, DOI 10.1002/ptr.6400
   Sansbury BE, 2021, AM J PATHOL, V191, P1049, DOI 10.1016/j.ajpath.2021.02.015
   Savitri C, 2024, ADV SCI, V11, DOI 10.1002/advs.202305852
   Schröder A, 2022, ALLERGY, V77, P856, DOI 10.1111/all.15072
   Seidel D, 2022, BMC SURG, V22, DOI 10.1186/s12893-022-01863-x
   Seidel D, 2022, J FOOT ANKLE RES, V15, DOI 10.1186/s13047-022-00569-w
   Seiser S, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-20997-9
   Shams F, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-23304-8
   Short WD, 2022, FASEB J, V36, DOI 10.1096/fj.201901024RR
   Shou KQ, 2017, BIOMED RES INT, V2017, DOI 10.1155/2017/7920265
   Son B, 2019, J DERMATOL SCI, V96, P81, DOI 10.1016/j.jdermsci.2019.10.004
   Song YL, 2023, ADV SCI, V10, DOI 10.1002/advs.202304023
   Soundrarajan N, 2023, INT J MOL SCI, V24, DOI 10.3390/ijms241411658
   Stratmann B, 2020, JAMA NETW OPEN, V3, DOI 10.1001/jamanetworkopen.2020.10411
   Strudwick XL, 2020, ADV WOUND CARE, V9, P637, DOI 10.1089/wound.2019.1035
   Sumpio BJ, 2025, SCI REP-UK, V15, DOI 10.1038/s41598-025-16914-5
   Suzuki H, 2025, JAMA NETW OPEN, V8, DOI 10.1001/jamanetworkopen.2025.6781
   Tahir Mahmood D, 2023, Arch Razi Inst, V78, P1323, DOI [10.32592/ari.2023.78.4.1323, 10.32592/ARI.2023.78.4.1323]
   Takaya K, 2022, INT J MOL SCI, V23, DOI 10.3390/ijms23137087
   Tang FJ, 2023, CLIN MED INSIGHTS-EN, V16, DOI 10.1177/11795514231196464
   Tarafder A, 2026, B MATH BIOL, V88, DOI 10.1007/s11538-026-01615-5
   Theocharidis G, 2020, DIABETES, V69, P2157, DOI 10.2337/db20-0188
   Valsami EA, 2025, ADV THER, V42, P3089, DOI 10.1007/s12325-025-03212-9
   Vardakostas D, 2025, J PERS MED, V15
   Wang B, 2025, J ETHNOPHARMACOL
   Wang GF, 2023, EXP EYE RES, V231, DOI 10.1016/j.exer.2023.109484
   Wang HT, 2024, INFLAMMATION, V47, P1667, DOI 10.1007/s10753-024-02000-x
   Wang HM, 2026, BIOACT MATER, V61, P758, DOI 10.1016/j.bioactmat.2026.02.054
   Wang QQ, 2024, EUR J CLIN MICROBIOL, V43, P2383, DOI 10.1007/s10096-024-04955-z
   Wang SL, 2024, CELL MOL IMMUNOL, V21, P620, DOI 10.1038/s41423-024-01158-6
   Wang XH, 2022, INT J BIOL SCI, V18, P4388, DOI 10.7150/ijbs.69890
   Wang Y, 2025, NATURE, V644, DOI 10.1038/s41586-025-09234-1
   Wang ZT, 2025, BIOACT MATER, V50, P30, DOI [10.1016/j.bioactmat.2025.03.025, 10.1016/j.bioactmat.2025.03.025]
   Wattanaploy S, 2017, INT J LOW EXTR WOUND, V16, P45, DOI 10.1177/1534734617690949
   Wee WKJ, 2022, CELL DEATH DIS, V13, DOI 10.1038/s41419-022-04638-7
   Wei YZ, 2023, IMMUN INFLAMM DIS, V11, DOI 10.1002/iid3.898
   Wilkinson HN, 2024, J INVEST DERMATOL, V144, DOI 10.1016/j.jid.2024.01.018
   Wong SL, 2015, NAT MED, V21, P815, DOI 10.1038/nm.3887
   Wu D, 2025, STEM CELL RES THER, V16, DOI 10.1186/s13287-025-04248-y
   Wu Y, 2023, SAUDI MED J, V44, P1020, DOI 10.15537/smj.2023.44.20230386
   Wynn TA, 2016, IMMUNITY, V44, P450, DOI 10.1016/j.immuni.2016.02.015
   Xiang HB, 2024, STEM CELL RES THER, V15, DOI 10.1186/s13287-024-04069-5
   Xiao YQ, 2024, ADV SCI, V11, DOI 10.1002/advs.202401195
   Xie HT, 2025, BMC ENDOCR DISORD, V25, DOI 10.1186/s12902-025-01837-z
   Xing DD, 2024, BIOMACROMOLECULES, V25, P7529, DOI 10.1021/acs.biomac.4c01276
   Xiong Y, 2023, ADV MATER, V35, DOI 10.1002/adma.202212300
   Yamane T, 2019, MOL CELL BIOCHEM, V452, P177, DOI 10.1007/s11010-018-3423-8
   Yan D, 2020, INVEST OPHTH VIS SCI, V61, DOI 10.1167/iovs.61.14.22
   Yang BY, 2022, CELL REP, V40, DOI 10.1016/j.celrep.2022.111255
   Yang F, 2025, J CONTROL RELEASE, V377, P470, DOI 10.1016/j.jconrel.2024.11.047
   Yang P, 2025, ADV MATER, V37, DOI 10.1002/adma.202417801
   Yang SF, 2023, TRANSL RES, V254, P115, DOI 10.1016/j.trsl.2022.10.008
   Yang SF, 2023, INT J BIOL SCI, V19, P347, DOI 10.7150/ijbs.78046
   Yao M, 2014, INT WOUND J, V11, P586, DOI 10.1111/iwj.12005
   Yin K, 2023, J HAZARD MATER, V452, DOI 10.1016/j.jhazmat.2023.131236
   Yu DM, 2023, J CLIN INVEST, V133, DOI 10.1172/JCI170706
   Yu XP, 2023, PLOS ONE, V18, DOI 10.1371/journal.pone.0292684
   Yu X, 2024, MOL MED, V30, DOI 10.1186/s10020-024-00955-z
   Yu YZ, 2023, J NANOBIOTECHNOL, V21, DOI 10.1186/s12951-023-02073-0
   Yuan L, 2025, INT IMMUNOPHARMACOL, V151, DOI 10.1016/j.intimp.2025.114288
   Zandigohar M, 2024, J IMMUNOL, V213, DOI 10.4049/jimmunol.2400172
   Zhang C, 2024, BIOMACROMOLECULES, V25, P7750, DOI 10.1021/acs.biomac.4c01023
   Zhang CX, 2024, FASEB J, V38, DOI 10.1096/fj.202400006R
   Zhang J, 2023, ACTA PHARM SIN B, V13, P4318, DOI 10.1016/j.apsb.2022.11.006
   Zhang L, 2024, INT J BIOL MACROMOL, V278, DOI 10.1016/j.ijbiomac.2024.135194
   Zhang SP, 2019, BIOMATERIALS, V200, P35, DOI 10.1016/j.biomaterials.2019.02.006
   Zhang XD, 2025, SCI ADV, V11, DOI 10.1126/sciadv.adz5302
   Zhang YH, 2023, J NANOBIOTECHNOL, V21, DOI 10.1186/s12951-023-02209-2
   Zhang Y, 2023, ACTA PHARMACOL SIN, V44, P999, DOI 10.1038/s41401-022-01013-2
   Zhao LE, 2026, ADV HEALTHC MATER, V15, DOI 10.1002/adhm.202505184
   Zhao Q, 2025, SCI REP
   Zhou BS, 2020, NAT IMMUNOL, V21, P1430, DOI 10.1038/s41590-020-0764-8
   Zhou Y, 2022, STEM CELL RES THER, V13, DOI 10.1186/s13287-022-02980-3
   Zhou ZP, 2023, BIOMATERIALS, V299, DOI 10.1016/j.biomaterials.2023.122141
   Zhu H J, 2019, Zhonghua Shao Shang Za Zhi, V35, P298, DOI 10.3760/cma.j.issn.1009-2587.2019.04.010
   Zhu ZG, 2020, BIOCHEM BIOPH RES CO, V524, P916, DOI 10.1016/j.bbrc.2020.02.013
   Zhuang ZM, 2025, J NANOBIOTECHNOL, V23, DOI 10.1186/s12951-025-03773-5
   Zulbaran-Rojas A, 2023, J DIABETES SCI TECHN, V17, P15, DOI 10.1177/19322968211035128
NR 204
TC 0
Z9 1
U1 1
U2 1
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 2050-7771
J9 BIOMARK RES
JI Biomark. Res.
PD MAY 16
PY 2026
VL 14
IS 1
AR 75
DI 10.1186/s40364-026-00935-x
EA MAY 2026
PG 26
WC Oncology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Research & Experimental Medicine
GA KM7AT
UT WOS:001810603000002
PM 42141493
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Poortmans, N
   Berrevoet, F
AF Poortmans, N.
   Berrevoet, F.
TI Dynamic closure techniques for treatment of an open abdomen: an update
SO HERNIA
LA English
DT Review
DE Open abdomen; Dynamic closure; Negative pressure wound therapy;
   Systematic review
ID MEDIATED FASCIAL TRACTION; TEMPORARY ABDOMINAL CLOSURE; ASSISTED WOUND
   CLOSURE; DELAYED CLOSURE; VACUUM; MANAGEMENT; THERAPY; CLASSIFICATION
AB Background The open abdomen (OA) is an important approach for managing intra-abdominal catastrophes and continues to be the standard of care. Despite this, challenges remain as it is associated with a high incidence of complications and poor outcomes. The objective is to perform a systematic review on dynamic closure techniques for fascial closure during open abdomen management. Methods An electronic database search was conducted involving 4 different databases (MEDLINE (PubMed), SCOPUS, WEB OF SCIENCE (WOS) and EMBASE). All studies that described dynamic closure techniques in OA patients were eligible for inclusion. Data collected were synthesized by each outcome of interest. Results Thirteen studies were included in the final synthesis. Overall methodological quality was low with a high number of retrospective observational studies and low number of patients. All included studies are observational cohort studies. No studies reported on the use of either Wittmann patch, dynamic retention sutures or ABRA system. Two studies reported on the ABRA system in combination with Negative Pressure Wound Therapy (NPWT), while 9 reported on mesh-mediated fascial traction (MMFT) combined with NPWT. Other types of fascial traction, either by dynamic suture lines or by a self-made silastic tube system, and NPWT were reported in 2 studies. Overall closure rates are 93.2% for the ABRA system + NPWT versus 72.0% for the mesh-mediated fascial traction + NPWT. Conclusion Careful selection and good management of OA patients will avoid prolonged treatment and facilitate early fascial closure. Future research should focus on comparison of different temporary dynamic closure techniques to evolve toward best treatment options, in terms of both fascial closure rates and long-term incisional hernia rates.
C1 [Poortmans, N.; Berrevoet, F.] Ghent Univ Hosp, Dept Gen & HPB Surg & Liver Transplantat, Corneel Heymanslaan 10, B-9000 Ghent, Belgium.
C3 Ghent University; Ghent University Hospital
RP Berrevoet, F (通讯作者)，Ghent Univ Hosp, Dept Gen & HPB Surg & Liver Transplantat, Corneel Heymanslaan 10, B-9000 Ghent, Belgium.
EM Frederik.Berrevoet@UGent.be
RI ; Berrevoet, Frederik/A-6117-2008
OI Poortmans, Natalie/0000-0001-5270-2678; 
CR Acosta S, 2017, EUR J VASC ENDOVASC, V54, P697, DOI 10.1016/j.ejvs.2017.09.002
   [Anonymous], 2017, World Journal of Emergency Surgery
   Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
   Berrevoet F, 2018, FRONT SURG, V5, DOI 10.3389/fsurg.2018.00011
   Björck M, 2016, SCAND J SURG, V105, P5, DOI 10.1177/1457496916631853
   Björck M, 2009, WORLD J SURG, V33, P1154, DOI 10.1007/s00268-009-9996-3
   Coccolini F, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0167-4
   Cristaudo A, 2017, AM SURGEON, V83, P191
   De Waele JJ, 2015, ANAESTH INTENSIVE TH, V47, P372, DOI 10.5603/AIT.a2015.0023
   Demetriades D, 2012, INT WOUND J, V9, P17, DOI 10.1111/j.1742-481X.2012.01018.x
   Egger M, 2007, SYSTEMATIC REV HLTH, P43
   Fortelny RH, 2014, SURG ENDOSC, V28, P735, DOI 10.1007/s00464-013-3251-6
   Haddock C, 2013, AM J SURG, V205, P528, DOI 10.1016/j.amjsurg.2013.01.028
   Jakob MO, 2018, HERNIA, V22, P785, DOI 10.1007/s10029-018-1798-9
   Lambertz A, 2015, INT J SURG, V13, P12, DOI 10.1016/j.ijsu.2014.11.025
   Liberati A, 2009, BMJ-BRIT MED J, V339, DOI 10.1136/bmj.b2700
   Loftus TJ, 2019, J TRAUMA ACUTE CARE, V86, P670, DOI 10.1097/TA.0000000000002170
   López-Cano M, 2018, HERNIA, V22, P921, DOI 10.1007/s10029-018-1818-9
   López-Cano M, 2013, WORLD J GASTRO SURG, V5, P314, DOI 10.4240/wjgs.v5.i12.314
   MORI RV, 2019, HERNIA
   Pereira-Warr S, 2018, HERNIA, V22, P691, DOI 10.1007/s10029-018-1773-5
   Petersson P, 2019, SCAND J SURG, V108, P216, DOI 10.1177/1457496918818979
   Petersson U, 2007, WORLD J SURG, V31, P2133, DOI 10.1007/s00268-007-9222-0
   Salamone G, 2018, WORLD J SURG, V42, P1679, DOI 10.1007/s00268-017-4354-3
   Sartelli M, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0032-7
   Seternes A, 2017, WORLD J SURG, V41, P152, DOI 10.1007/s00268-016-3694-8
   Steenkamp CJ, 2018, S AFR J SURG, V56, P28, DOI 10.17159/2078-5151/2018/v56n4a2674
   Tian WL, 2019, MEDICINE, V98, DOI 10.1097/MD.0000000000016617
   Tolonen M, 2017, J TRAUMA ACUTE CARE, V82, P1100, DOI 10.1097/TA.0000000000001452
   Wang YF, 2019, WORLD J SURG, V43, P3044, DOI 10.1007/s00268-019-05166-w
   Willms A, 2017, HERNIA, V21, P279, DOI 10.1007/s10029-017-1572-4
   Yetisir F, 2017, INDIAN J SURG, V79, P38, DOI 10.1007/s12262-015-1422-5
NR 32
TC 14
Z9 19
U1 0
U2 6
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1265-4906
EI 1248-9204
J9 HERNIA
JI Hernia
PD APR
PY 2020
VL 24
IS 2
SI SI
BP 325
EP 331
DI 10.1007/s10029-020-02130-9
EA FEB 2020
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA KW4SU
UT WOS:000511044800002
PM 32020342
OA Green Published
DA 2026-07-24
ER

PT J
AU Massey, LH
   Pathak, S
   Bhargava, A
   Smart, NJ
   Daniels, IR
AF Massey, L. H.
   Pathak, S.
   Bhargava, A.
   Smart, N. J.
   Daniels, I. R.
TI The use of adjuncts to reduce seroma in open incisional hernia repair: a
   systematic review
SO HERNIA
LA English
DT Review
DE Abdominal wall; Hernia; Mesh; Seroma; Incisional; Negative pressure
   wound therapy
ID NEGATIVE-PRESSURE THERAPY; FIBRIN SEALANT; SUBCUTANEOUS TALC; QUILTING
   SUTURES; PREVENTION; ABDOMINOPLASTY; DISSECTION; CLASSIFICATION;
   PREDICTORS; MASTECTOMY
AB Seroma formation remains a common complication after an incisional hernia repair. The use of surgical drains is widespread, but evidence for their use and other adjuncts is limited. Our aim was to perform a systematic review of the literature on techniques used to reduce the incidence of post-operative seroma formation.
   A systematic search of PubMed and Embase databases was conducted using terms including "incisional hernia" and "seroma". All studies on adults undergoing open incisional hernia repair with at least one intervention designed to reduce seroma formation were included.
   Of the 1093 studies identified, 9 met the inclusion criteria. Medical talc: one cohort study of 74 patients undergoing talc application following pre-peritoneal mesh placement found a significantly decreased rate of seroma formation of 20.8 versus 2.7% (p < 0.001), but a retrospective study including 21 patients with onlay mesh found an increased rate of 76% seroma formation from 9.5% (p = 0.001). Fibrin glue: one comparative study including 60 patients found a reduction in seroma formation from 53 to 10% (p = 0.003), whereas a retrospective study of 250 patients found no difference (11 vs. 4.9% p = 0.07). Negative pressure wound therapy: four retrospective studies including a total of 358 patients found no difference in seroma outcome. Others: one randomised study of 42 patients undergoing either suction drainage or "quilting" sutures found no difference in seroma formation.
   There is currently insufficient quality evidence to recommend any of the investigated methods, some of which incur significant additional cost.
C1 [Massey, L. H.; Smart, N. J.; Daniels, I. R.] Royal Devon & Exeter Hosp, Exeter Surg Hlth Serv Res Unit, Barrack Rd, Exeter EX2 5DW, Devon, England.
   [Pathak, S.] Bristol Royal Infirm & Gen Hosp, Upper Maudlin St, Bristol BS2 8HW, Avon, England.
   [Bhargava, A.] Queen Mary Univ London, Inst Hlth Sci, Mile End Rd, London E1 4NS, England.
C3 University of Exeter; Bristol Royal Infirmary; University of London;
   Queen Mary University London
RP Massey, LH (通讯作者)，Royal Devon & Exeter Hosp, Exeter Surg Hlth Serv Res Unit, Barrack Rd, Exeter EX2 5DW, Devon, England.
EM lisahmassey@gmail.com
RI ; Daniels, Ian/OGR-1767-2025; Smart, Neil/O-2842-2019
OI Massey, Lisa/0000-0002-1699-8034; Daniels, Ian/0000-0002-9114-0812;
   Pathak, Samir/0000-0002-0535-1470; 
FU Medtronic
FX LM declares no conflict of interest. SP declares no conflict of
   interest. AB declares conflict of interest not directly related to the
   submitted work (speaker's fees from Medtronic). NS declares conflict of
   interest not directly related to the submitted work (speaker's fees from
   Medtronic). ID declares conflict of interest not directly related to the
   submitted work (grants, personal fees and non-financial support from
   Medtronic).
CR Ali-Khan AS, 2009, J PLAST RECONSTR AES, V62, P1063, DOI [10.1016/j.bjps.2007.12.040, 10.1016/j.bjps.2008.08.016]
   [Anonymous], 2017, Textbook of Hernia
   [Anonymous], PROSPERO INT REG SYS
   Azoury SC, 2015, HERNIA, V19, P935, DOI 10.1007/s10029-015-1403-4
   Bedi Amrit Pal Singh, 2007, J Minim Access Surg, V3, P83, DOI 10.4103/0972-9941.37190
   Bercial ME, 2012, AESTHET PLAST SURG, V36, P370, DOI 10.1007/s00266-011-9807-8
   Bouvier A, 2014, HERNIA, V18, P501, DOI 10.1007/s10029-014-1264-2
   Choi MS, 2012, ANN PLAS SURG, V69, P209, DOI 10.1097/SAP.0b013e318226b516
   Condé-Green A, 2013, ANN PLAS SURG, V71, P394, DOI 10.1097/SAP.0b013e31824c9073
   de Vries M, 2009, ANN SURG ONCOL, V16, P2840, DOI 10.1245/s10434-009-0602-6
   Deerenberg EB, 2015, HERNIA, V19, P89, DOI 10.1007/s10029-014-1321-x
   den Hartog Dennis, 2008, Cochrane Database Syst Rev, pCD006438, DOI 10.1002/14651858.CD006438.pub2
   Diener MK, 2010, ANN SURG, V251, P843, DOI 10.1097/SLA.0b013e3181d973e4
   Dindo D, 2004, ANN SURG, V240, P205, DOI [10.17116/hirurgia2018090162, 10.1097/01.sla.0000133083.54934.ae]
   Dunn CJ, 1999, DRUGS, V58, P863, DOI 10.2165/00003495-199958050-00010
   Fang ZX, 2015, ANZ J SURG, V85, P910, DOI 10.1111/ans.13234
   Gassman A, 2015, HERNIA, V19, P273, DOI 10.1007/s10029-014-1312-y
   Gurusamy KS, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD005570.pub4
   Higgins JPT, 2011, BMJ-BRIT MED J, V343, DOI 10.1136/bmj.d5928
   Kaafarani HMA, 2009, AM J SURG, V198, P639, DOI 10.1016/j.amjsurg.2009.07.019
   Klima DA, 2012, J AM COLL SURGEONS, V214, P338, DOI 10.1016/j.jamcollsurg.2011.11.004
   Klima DA, 2011, AM SURGEON, V77, P888
   Klinge U, 2005, WORLD J SURG, V29, P1066, DOI 10.1007/s00268-005-7970-2
   Klink CD, 2010, HERNIA, V14, P175, DOI 10.1007/s10029-009-0603-1
   Köhler G, 2014, WORLD J SURG, V38, P2797, DOI 10.1007/s00268-014-2691-z
   Moher D, 2009, PLOS MED, V6, DOI 10.1371/journal.pmed.1000097
   Morales-Conde S, 2012, HERNIA, V16, P261, DOI 10.1007/s10029-012-0911-8
   Muysoms FE, 2013, HERNIA, V17, P423, DOI 10.1007/s10029-013-1108-5
   Olona C, 2014, ADV SKIN WOUND CARE, V27, P77, DOI 10.1097/01.ASW.0000442873.48590.b5
   Ouldamer L, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2015-009903
   Parameswaran R, 2013, HERNIA, V17, P459, DOI 10.1007/s10029-013-1097-4
   Petro CC., 2016, HERNIA SURG, P15, DOI [10.1007/978-3-319-27470-6_2, DOI 10.1007/978-3-319-27470-6_2, 10.1007/978-3-319-27470-6, DOI 10.1007/978-3-319-27470-6]
   Pring CM, 2008, ANZ J SURG, V78, P903, DOI 10.1111/j.1445-2197.2008.04689.x
   Qvamme G, 2015, BRIT J SURG, V102, P1195, DOI 10.1002/bjs.9874
   Satterwhite TS, 2012, ANN PLAS SURG, V68, P382, DOI 10.1097/SAP.0b013e31823b68b1
   Schachtrupp A, 2003, BJS-BRIT J SURG, V90, P114, DOI 10.1002/bjs.4023
   Sforza M, 2015, AESTHET SURG J, V35, P574, DOI 10.1093/asj/sju103
   Shaw P, 2004, COCHRANE DB SYST REV, V1, DOI DOI 10.1002/14651858.CD002916.PUB2
   Skillman JM, 2014, AESTHET PLAST SURG, V38, P446, DOI 10.1007/s00266-013-0267-1
   Slim K, 2003, ANZ J SURG, V73, P712, DOI 10.1046/j.1445-2197.2003.02748.x
   Soares KC, 2015, AM J SURG, V209, P324, DOI 10.1016/j.amjsurg.2014.06.022
   Susmallian S, 2001, Hernia, V5, P139
   Taghizadeh R, 2008, J PLAST RECONSTR AES, V61, P636, DOI 10.1016/j.bjps.2007.03.019
   Westphalen AP, 2015, ACTA CIR BRAS, V30, P844, DOI 10.1590/S0102-865020150120000009
NR 44
TC 23
Z9 27
U1 1
U2 10
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1265-4906
EI 1248-9204
J9 HERNIA
JI Hernia
PD APR
PY 2018
VL 22
IS 2
BP 273
EP 283
DI 10.1007/s10029-017-1690-z
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GA3SB
UT WOS:000428248700008
PM 29071497
DA 2026-07-24
ER

PT J
AU Sweitzer, K
   Tomtschik, J
   Butterfield, J
   Bell, D
AF Sweitzer, Keith
   Tomtschik, Julia
   Butterfield, James
   Bell, Derek
TI Outcomes Following Use of Negative-Pressure Wound Therapy Over
   Autologous Meshed and Non-Meshed Skin Grafts
SO JOURNAL OF BURN CARE & RESEARCH
LA English
DT Article
ID BURNS
AB Negative-pressure wound therapy (NPWT) over split thickness skin grafts can control exudate, decrease infection rates, and improve revascularization. However, no study specifically addresses differences in outcomes between meshed/perforated and non-meshed autologous skin grafts dressed with NPWT. Through retrospective chart review, patients undergoing autologous split thickness skin grafting with a NPWT dressing for any burn injury over a 10-month period were identified. Data on etiology, graft take, meshed/perforated or non-meshed graft, graft size, and seroma/hematoma incidence were collected. Our study included 123 patients who had STSG with NPWT and consisted of 57% males, 57% Caucasian, and an average age of 41. Burn injury etiologies consisted of scald (55%), chemical (25%), flame (15%), and contact (5%). Average 2nd degree TBSA in our cohort was 2.34%, 3rd degree TBSA 4.50%, and total TBSA 5.35%. 66.7% of patients received non-meshed grafts, and these patients had an average graft area of 76.5 cm(2). 33.3% of patients received meshed grafts, with an average graft area of 163.5 cm(2). Non-meshed burn grafts were significantly smaller than meshed grafts (P = .04). There was 100% graft take and 0% seroma/hematoma formation in all patients. Data was analyzed using an unpaired student's T test and ANOVA testing. There were no statistically significant differences in patient demographics, or burn etiology. There exist many options for dressings after repair of burn injuries, each with its own unique advantages. There were, however, no differences in graft take or incidence of seroma/hematoma formation using a NPWT dressing over autologous meshed grafts vs non-meshed grafts. Our data shows that NPWT use as a bolster dressing is safe and efficacious overlying meshed skin grafts and non-meshed grafts.
C1 [Sweitzer, Keith; Tomtschik, Julia; Butterfield, James; Bell, Derek] Univ Rochester, Dept Surg, Div Plast Surg, 601 Elmwood Ave, Rochester, NY 14642 USA.
C3 University of Rochester
RP Bell, D (通讯作者)，Univ Rochester, Dept Surg, Div Plast Surg, 601 Elmwood Ave, Rochester, NY 14642 USA.
EM Keithsweitzer6@gmail.com; Derek_Bell@urmc.rochester.edu
RI Sweitzer, Keith/HTP-8566-2023
OI Tomtschik, Julia/0000-0001-6982-7856
CR Archer SB, 1998, J BURN CARE REHABIL, V19, P33, DOI 10.1097/00004630-199801000-00009
   Borgquist O, 2010, ANN PLAS SURG, V64, P789, DOI 10.1097/SAP.0b013e3181ba578a
   Braza ME., 2021, STATPEARLS INTERNET
   Chacon MA, 2020, J BURN CARE RES, V41, P849, DOI 10.1093/jbcr/irz208
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Kantak NA, 2017, CLIN PLAST SURG, V44, P671, DOI 10.1016/j.cps.2017.02.023
   Kantak NA, 2016, BURNS, V42, P1623, DOI 10.1016/j.burns.2016.06.011
   Lalezari S, 2017, INT WOUND J, V14, P649, DOI 10.1111/iwj.12658
   Nikkhah D, 2015, BURNS, V41, P257, DOI 10.1016/j.burns.2014.07.023
   Panayi AC, 2017, World Journal of Dermatology, V6, P1, DOI [10.5314/wjd.v6.i1.1, 10.5314/wjd.v6.i1.1, DOI 10.5314/WJD.V6.I1.1]
   Patmo ASP, 2014, ADV WOUND CARE, V3, P383, DOI 10.1089/wound.2013.0510
NR 11
TC 2
Z9 3
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1559-047X
EI 1559-0488
J9 J BURN CARE RES
JI J. Burn Care Res.
PD JAN 5
PY 2023
VL 44
IS 1
BP 136
EP 139
DI 10.1093/jbcr/irac122
EA SEP 2022
PG 4
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA 7S7CQ
UT WOS:000860799300001
PM 36037524
DA 2026-07-24
ER

PT J
AU de Henau, M
   Kruit, AS
   Ulrich, DJO
AF de Henau, Melissa
   Kruit, Anne Sophie
   Ulrich, Dietmar J. O.
TI Reconstruction of full thickness wounds using glyaderm in a
   single-staged procedure
SO CELL AND TISSUE BANKING
LA English
DT Article
DE Full thickness wound; Dermal substitute; Glyaderm; Skin graft; Negative
   pressure wound therapy
AB Introduction In large full-thickness skin defects, donor site morbidity limits the available thickness and surface of skin autografts and therefore only split-thickness skin grafts are possible for reconstruction. Dermal equivalents can be added to these split-thickness grafts to acquire an anatomically better skin reconstruction. Glyaderm is a human derived, acellular dermis and up until now has only been used in a two-staged procedure. This report describes results of a case series using Glyaderm and split-thickness skin grafts in a single-staged procedure. Methods Glyaderm was introduced in 2017 in Radboudumc (Nijmegen, The Netherlands). Glyaderm and autologous split-skin grafts were simultaneously applied to the wounds. In cases with large wound surfaces or wounds covering highly mobile areas, negative pressure wound therapy was additionally applied. The first ten cases were followed with regular intervals post-operatively, assessing graft take, scar appearance, post-operative wound problems and re-interventions. Results Patients were aged 3 weeks to 76 years-old. Treated skin surface varied from 1-16% total body surface. Wounds resulted from trauma (n = 4), burns (n = 4) or soft tissue infections (n = 2). Follow-up varied from 4 months to 1.5 years. No complications occurred after surgery. Average take rate was 98%. Two patients had a later re-intervention to further improve the aesthetic appearance of the scarred area. Conclusion Our first results with the application of Glyaderm in a single-staged procedure provided good healing, graft take and scar appearance. Glyaderm was found a suitable dermal substitute in the treatment of full thickness wounds.
C1 [de Henau, Melissa; Kruit, Anne Sophie; Ulrich, Dietmar J. O.] Radboud Univ Nijmegen, Med Ctr, Dept Plast & Reconstruct Surg, Geert Grootepl Zuid 10, NL-6523 GA Nijmegen, Netherlands.
C3 Radboud University Nijmegen
RP Kruit, AS (通讯作者)，Radboud Univ Nijmegen, Med Ctr, Dept Plast & Reconstruct Surg, Geert Grootepl Zuid 10, NL-6523 GA Nijmegen, Netherlands.
EM annesophie.kruit@radboudumc.nl
RI Kruit, Anne Sophie/B-4061-2017
OI Kruit, Anne Sophie/0000-0001-6368-9974
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Butterfield JL, 2013, PLAST RECONSTR SURG, V131, P940, DOI 10.1097/PRS.0b013e3182865ab3
   Demling RH, 2007, BIOSYNTHETIC SKIN SU
   Hutchison RL, 2013, J WOUND CARE, V22, P708, DOI 10.12968/jowc.2013.22.12.708
   Lee KH, 2000, YONSEI MED J, V41, P774, DOI 10.3349/ymj.2000.41.6.774
   Liu Wei, 2016, Zhonghua Shao Shang Za Zhi, V32, P356, DOI 10.3760/cma.j.issn.1009-2587.2016.06.011
   Miller Christine, 2012, J Am Coll Clin Wound Spec, V4, P61, DOI 10.1016/j.jccw.2013.11.002
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Nguyen DQA, 2010, BURNS, V36, P23, DOI 10.1016/j.burns.2009.07.011
   Pirayesh A., 2007, BURNS, V33, pS13, DOI [10.1016/j.burns.2006.10.312, DOI 10.1016/J.BURNS.2006.10.312]
   Pirayesh A, 2015, BURNS, V41, P132, DOI 10.1016/j.burns.2014.05.013
   Richters CD, 2008, CELL TISSUE BANK, V9, P309, DOI 10.1007/s10561-008-9073-4
   Shahrokhi S, 2014, WOUND REPAIR REGEN, V22, P14, DOI 10.1111/wrr.12119
   Sinha K, 2013, ADV ORTHOP, V2013, DOI 10.1155/2013/245940
   Truong Anh-Tuan N, 2005, J Burns Wounds, V4, pe4
   van der Veen VC, 2010, BURNS, V36, P305, DOI 10.1016/j.burns.2009.07.012
   WAINWRIGHT DJ, 1995, BURNS, V21, P243, DOI 10.1016/0305-4179(95)93866-I
NR 17
TC 7
Z9 7
U1 0
U2 1
PU SPRINGER
PI DORDRECHT
PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
SN 1389-9333
EI 1573-6814
J9 CELL TISSUE BANK
JI Cell Tissue Banking
PD JUN
PY 2021
VL 22
IS 2
SI SI
BP 199
EP 205
DI 10.1007/s10561-021-09907-x
EA FEB 2021
PG 7
WC Cell Biology; Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Engineering
GA SN3LB
UT WOS:000620867900001
PM 33620693
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Tyagi, V
   Kahan, J
   Huang, P
   Leslie, MP
   Rubin, LE
   Gibson, DH
AF Tyagi, Vineet
   Kahan, Joseph
   Huang, Patrick
   Leslie, Michael P.
   Rubin, Lee E.
   Gibson, David H.
TI Negative Pressure Incisional Therapy and Infection After Direct Anterior
   Approach Primary Total Hip Arthroplasy
SO ORTHOPEDICS
LA English
DT Article
ID PERIPROSTHETIC JOINT INFECTION; WOUND THERAPY; RISK-FACTORS; KNEE
   ARTHROPLASTY; UNITED-STATES; REVISION HIP; EPIDEMIOLOGY; PREVALENCE;
   DRESSINGS; OBESITY
AB With the aging of the US population, total hip arthroplasty (THA) is becoming an increasingly common procedure. A major concern after THA is reducing infection rates, as infections can cause devastating complications. Improve A sterile technique, standardized infection control protocols, and novel dressing have been used to reduce postoperative surgical site infections (SSIs), the of either silver-impregnated dry dressings or easily applied incisional negative pressure dressings is aimed at reducing the rates of SSIs after primary anterior THA. The authors retrospectively reviewed the medical records of 275 patients who underwent anterior THA at their institution during a 1-year period. Patients were separated into groups based on their surgical dressing. Rates of SSI were documented, and the effects of various factors, including age, sex, body mass index, and comorbidities, were compared between the 2 cohorts. the authors also analyzed high-risk patients to determine whether easily applied incisional negative pressure dressings reduced infections. Me use of easily applied incisional negative pressure dressings after primary anterior THA did not have a statistically significant impact on SSI rate (P =.42). There was also no difference in SSI, readmission, or reoperation in the high-risk group. The goal of using an incisional negative pressure wound therapy device is to help further decrease the risk of SSI. This study's findings suggest that the SSI rate in this group did not differ from that in the standard dressing group, such that the prophylactic use of a negative pressure wound therapy device is riot indicated for either standard or high-risk patients undergoing primary anterior approach THA.
C1 [Tyagi, Vineet; Kahan, Joseph; Huang, Patrick; Leslie, Michael P.; Rubin, Lee E.; Gibson, David H.] Yale Univ, Sch Med, Dept Orthopaed & Rehabil, 47 Coll St, New Haven, CT 06520 USA.
C3 Yale University
RP Tyagi, V (通讯作者)，Yale Univ, Sch Med, Dept Orthopaed & Rehabil, 47 Coll St, New Haven, CT 06520 USA.
EM vineet.tyagi@yale.edu
RI Kahan, Joseph/AAH-2682-2019
CR Baek SH, 2014, WORLD J ORTHOP, V5, P362, DOI 10.5312/wjo.v5.i3.362
   Bozic KJ, 2012, J BONE JOINT SURG AM, V94A, P794, DOI 10.2106/JBJS.K.00072
   Bozic KJ, 2009, J BONE JOINT SURG AM, V91A, P128, DOI 10.2106/JBJS.H.00155
   Cooper HJ, 2016, J ARTHROPLASTY, V31, P1047, DOI 10.1016/j.arth.2015.11.010
   Dale H, 2009, ACTA ORTHOP, V80, P639, DOI 10.3109/17453670903506658
   Flegal KM, 2012, JAMA-J AM MED ASSOC, V307, P491, DOI [10.1001/jama.2012.39, 10.2337/dc11-1299]
   Gwam CU, 2017, J ARTHROPLASTY, V32, P2088, DOI 10.1016/j.arth.2017.02.046
   Jones Richard E, 2010, Orthopedics, V33, P660, DOI 10.3928/01477447-20100722-35
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Kurtz S, 2007, J BONE JOINT SURG AM, V89A, P780, DOI 10.2106/JBJS.F.00222
   Kurtz SM, 2008, J ARTHROPLASTY, V23, P984, DOI 10.1016/j.arth.2007.10.017
   Kurtz SM, 2012, J ARTHROPLASTY, V27, P61, DOI 10.1016/j.arth.2012.02.022
   Mont MA, 2016, J ARTHROPLASTY, V31, P284, DOI 10.1016/j.arth.2015.07.010
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Phillips JE, 2006, J BONE JOINT SURG BR, V88B, P943, DOI 10.1302/0301-620X.88B7.17150
   Pivec R, 2012, LANCET, V380, P1768, DOI 10.1016/S0140-6736(12)60607-2
   Raikin SM, 2010, J BONE JOINT SURG AM, V92A, P2150, DOI 10.2106/JBJS.I.00870
   Redfern RE, 2017, J ARTHROPLASTY, V32, P3333, DOI 10.1016/j.arth.2017.06.019
   Saleh K, 2002, J ORTHOP RES, V20, P506, DOI 10.1016/S0736-0266(01)00153-X
   Siqueira MBP, 2016, WORLD J ORTHOP, V7, P30, DOI 10.5312/wjo.v7.i1.30
   Springer BD, 2013, J ARTHROPLASTY, V28, P714, DOI 10.1016/j.arth.2013.02.011
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Whiting DR, 2011, DIABETES RES CLIN PR, V94, P311, DOI 10.1016/j.diabres.2011.10.029
NR 25
TC 12
Z9 12
U1 0
U2 0
PU SLACK INC
PI THOROFARE
PA 6900 GROVE RD, THOROFARE, NJ 08086 USA
SN 0147-7447
EI 1938-2367
J9 ORTHOPEDICS
JI Orthopedics
PD NOV-DEC
PY 2019
VL 42
IS 6
BP E539
EP E544
DI 10.3928/01477447-20190906-06
PG 6
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA JP8LU
UT WOS:000498511000009
PM 31505014
DA 2026-07-24
ER

PT J
AU Molska, M
   Wojciech, M
   Pieszko, K
   Ciesla, S
   Murawa, D
AF Molska, Maja
   Wojciech, Magdalena
   Pieszko, Karolina
   Ciesla, Slawomir
   Murawa, Dawid
TI Randomized controlled trial comparing single-use negative-pressure wound
   therapy (sNPWT) with standard dressings during tissue
   expander-to-implant exchanges. Assessment of risk factors for impaired
   wound healing and clinical indications for sNPWT
SO EJSO
LA English
DT Article
DE Breast reconstruction; sNPWT; Scar; Wound healing; Mathematical model;
   Variable selection
ID MASTECTOMY; COMPLICATIONS
AB Background: Breast reconstruction is a key step in the physical and social recovery of breast cancer patients. Optimal wound healing is crucial not only for aesthetic outcomes but also for the uninterrupted continuation of adjuvant oncologic therapy, which can significantly impact overall prognosis. Purpose: The study compared single-use negative pressure wound therapy (sNPWT) with standard dressings during the second stage of breast reconstruction - tissue expander-to-implant exchanges. Additionally, it aimed to identify factors associated with an increased risk of impaired wound healing and postoperative complications, to determine clinical conditions in which the prophylactic use of sNPWT is most beneficial. Methods: The study evaluated 38 women undergoing the second stage of two-stage breast reconstruction after unilateral mastectomy. Each patient received either sNPWT or a standard dressing postoperatively, with allocation randomized and independent of both physician and patient. Scar characteristics, including elasticity, temperature, healing, and appearance, were assessed. Results: A significant difference in skin elasticity in favor of sNPWT was observed after 7 days, while the most pronounced difference was seen after 6 months (mean 0.688 vs. 0.480). No significant differences were found in temperature. Visually, sNPWT-treated scars appeared narrower and less prominent. The mathematical model identified radiotherapy as the only factor significantly associated with poor healing (p-value = 0.025). Conclusion: Compared to standard dressings, sNPWT demonstrates clear advantages in improving scars' elasticity and aesthetic appearance. Its application significantly reduces postoperative complications, including the risk of implant loss, making it a valuable option in breast reconstruction.
C1 [Molska, Maja] Univ Hosp Zielona Gora, Clin Dept Gen & Oncol Surg, PL-65046 Zielona Gora, Poland.
   [Molska, Maja; Pieszko, Karolina; Murawa, Dawid] Univ Zielona Gora, Dept Surg & Oncol, Coll Med, PL-65046 Zielona Gora, Poland.
   [Wojciech, Magdalena] Univ Zielona Gora, Inst Math, Dept Appl Math, PL-65046 Zielona Gora, Poland.
   [Pieszko, Karolina] Hosp Nowa Sol, Dept Plast Surg & Burns, PL-67100 Nowa Sol, Poland.
   [Ciesla, Slawomir; Murawa, Dawid] Reg Hosp Poznan, Greater Poland Specialist Ctr, Gen Surg & Surg Oncol Dept, PL-60479 Poznan, Poland.
C3 University of Zielona Gora; University of Zielona Gora
RP Molska, M (通讯作者)，Univ Hosp Zielona Gora, Clin Dept Gen & Oncol Surg, PL-65046 Zielona Gora, Poland.
EM majaa.molska@gmail.com
RI Wojciech, Magda/ABB-5969-2021
FU Smith Nephew
FX The open access is supported by Smith & Nephew. Smith & Nephew played no
   part in the design or execution of the study. Data collection, analysis
   and writing of this thesis was also done independently.
CR Akaike H., 1973, 2 INT S INFORM THEOR, P267
   Amin N, 2023, J WOUND OSTOMY CONT, V50, P203, DOI 10.1097/WON.0000000000000967
   [Anonymous], 2024, R Foundation for Statistical Computing
   Baron JM, 2020, DERMATOLOGY, V236, P593, DOI 10.1159/000505291
   Browne JP, 2017, CANCER-AM CANCER SOC, V123, P3460, DOI 10.1002/cncr.30788
   Catapani LB, 2016, J THER ULTRASOUND, V4, DOI 10.1186/s40349-016-0065-8
   Chiang SN, 2024, AESTHET SURG J, V44, P839, DOI 10.1093/asj/sjae054
   Crumley C, 2021, J WOUND OSTOMY CONT, V48, P195, DOI 10.1097/WON.0000000000000761
   Fleming CA, 2018, J HOSP INFECT, V99, P75, DOI 10.1016/j.jhin.2017.10.022
   Friedrich M, 2021, ANTICANCER RES, V41, P5365, DOI 10.21873/anticanres.15349
   Galimberti V, 2017, BREAST, V34, pS82, DOI 10.1016/j.breast.2017.06.034
   Grada A, 2022, CLIN DERMATOL, V40, P103, DOI 10.1016/j.clindermatol.2021.10.002
   Hilbe JM, 2009, CH CRC TEXT STAT SCI, P1
   Iqbal FM, 2020, J WOUND CARE, V29, P777, DOI 10.12968/jowc.2020.29.12.777
   Irwin GW, 2020, PRS-GLOB OPEN, V8, DOI 10.1097/GOX.0000000000002667
   Kawalkiewicz W, 2021, J COSMET DERMATOL-US, V20, P875, DOI 10.1111/jocd.13638
   Khalil H, 2015, WOUND REPAIR REGEN, V23, P550, DOI 10.1111/wrr.12307
   Kim DY, 2016, PLAST RECONSTR SURG, V138, P558, DOI 10.1097/PRS.0000000000002431
   Lewin R, 2014, J PLAST SURG HAND SU, V48, P10, DOI 10.3109/2000656X.2013.791625
   Liu DD, 2023, AESTHET PLAST SURG, V47, P2330, DOI 10.1007/s00266-023-03387-y
   Murphy JA, 2021, BJS OPEN, V5, DOI 10.1093/bjsopen/zraa042
   Ogawa R, 2021, J NIPPON MED SCH, V88, P2, DOI 10.1272/jnms.JNMS.2021_88-106
   Palve JS, 2020, BREAST CANCER RES TR, V182, P345, DOI 10.1007/s10549-020-05705-3
   Portet S, 2020, INFECT DIS MODEL, V5, P111, DOI 10.1016/j.idm.2019.12.010
   Rozinthe A, 2022, ORTHOP TRAUMATOL-SUR, V108, DOI 10.1016/j.otsr.2022.103338
   Ryu JY, 2022, AESTHET PLAST SURG, V46, P633, DOI 10.1007/s00266-020-02115-0
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Song JY, 2023, INT WOUND J, V20, P241, DOI 10.1111/iwj.13866
   Sorg H, 2017, EUR SURG RES, V58, P81, DOI 10.1159/000454919
   Vidalis BM, 2022, WORLD NEUROSURG, V159, pE407, DOI 10.1016/j.wneu.2021.12.063
   Vidya R, 2023, PRS-GLOB OPEN, V11, DOI 10.1097/GOX.0000000000005488
   Vollbach FH, 2022, J PERS MED, V12, DOI 10.3390/jpm12030332
   Wang PH, 2018, J CHIN MED ASSOC, V81, P94, DOI 10.1016/j.jcma.2017.11.002
   Wilkinson HN, 2021, WOUND REPAIR REGEN, V29, P298, DOI 10.1111/wrr.12888
   Zhao JL, 2024, INT WOUND J, V21, DOI 10.1111/iwj.14518
NR 35
TC 1
Z9 2
U1 2
U2 2
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0748-7983
EI 1532-2157
J9 EJSO-EUR J SURG ONC
JI EJSO
PD OCT
PY 2025
VL 51
IS 10
AR 110355
DI 10.1016/j.ejso.2025.110355
EA AUG 2025
PG 7
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA 5UB4F
UT WOS:001544342300003
PM 40752228
OA hybrid
DA 2026-07-24
ER

PT J
AU Ahmic, E
   Swatek, P
   Mykoliuk, I
   Busau, A
   Bamberg, P
   Smolle, J
   Smolle-Juettner, FM
   Lindenmann, J
AF Ahmic, Edin
   Swatek, Paul
   Mykoliuk, Iurii
   Busau, Anton
   Bamberg, Paul
   Smolle, Josef
   Smolle-Juettner, Freyja Maria
   Lindenmann, Jorg
TI Management and Outcomes of Sternoclavicular Joint Infections: A
   Retrospective Study
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE sternoclavicular joint infection; muscle flap reconstruction; chest
   wall; negative pressure wound therapy; sternum infection
ID PROPIONIBACTERIUM-ACNES; SURGICAL-MANAGEMENT; SEPTIC ARTHRITIS
AB Introduction: Sternoclavicular joint infections (SCJIs) are extremely rare, making up less than 1% of all septic arthritis cases. This retrospective study aims to evaluate the management and outcomes of SCJIs, including both surgical and non-surgical approaches. Methods: This retrospective study included 55 patients treated between January 2005 and December 2023 at the Division of Thoracic and Hyperbaric Surgery in Graz, Austria. Data on patient characteristics, treatment approach, and outcome were analyzed. Results: Out of the 55 patients, 50 (90.91%) underwent surgery. Among them, 21 (38.18%) had pleural involvement and 9 (16.36%) developed sepsis. Primary debridement and sternoclavicular joint resection with muscle flap closure were performed in 5 patients (9.3%), whilst debridement and negative pressure wound therapy (NPWT) followed by joint resection were applied in 32 patients (59.3%). In total, 15 (27.2%) of these cases required a secondary muscle flap. Positive cultures were found in 35 patients (63.64%), with Staphylococcus aureus being the most common pathogen. Multivariate analysis identified elevated CRP and leukocyte levels as significant predictors of sepsis. Defects requiring myoplastic procedures were associated with a higher risk of complications, sepsis, and prolonged hospital stays. Postoperative complications occurred in 20 patients (36.36%), but there was no 30-day mortality. Conclusions: SCJI is a rare but serious condition that requires prompt surgical intervention. Our findings suggest that combining surgical resection with NPWT and/or myocutaneous flap techniques is effective. Close monitoring of inflammatory markers is crucial for identifying sepsis risk and improving patient outcomes.
C1 [Ahmic, Edin; Swatek, Paul; Mykoliuk, Iurii; Busau, Anton; Bamberg, Paul; Smolle-Juettner, Freyja Maria; Lindenmann, Jorg] Med Univ Graz, Dept Surg, Div Thorac & Hyperbar Surg, A-8036 Graz, Austria.
   [Smolle, Josef] Med Univ Graz, Inst Med Informat Stat & Documentat, A-8036 Graz, Austria.
C3 Medical University of Graz; Medical University of Graz
RP Ahmic, E (通讯作者)，Med Univ Graz, Dept Surg, Div Thorac & Hyperbar Surg, A-8036 Graz, Austria.
EM edin.ahmic@medunigraz.at; paul.swatek@medunigraz.at;
   iurii.mykoliuk@medunigraz.at; anton.busau@medunigraz.at;
   paul.bamberg@stud.medunigraz.at; josef.smolle@medunigraz.at;
   freyja.smolle@medunigraz.at; jo.lindenmann@medunigraz.at
OI Swatek, Paul Thomas/0009-0008-8062-0918; Bamberg,
   Paul/0009-0000-2493-8069; Smolle-Juettner,
   Freyja-Maria/0000-0002-0875-0821; Smolle, Josef/0000-0002-8005-4660;
   Lindenmann, Joerg/0000-0003-1276-7666; Ahmic, Edin/0009-0006-8358-4225
CR Abu Arab W, 2011, EUR J CARDIO-THORAC, V40, P630, DOI 10.1016/j.ejcts.2010.12.037
   Al-Mufarrej F, 2013, J PLAST RECONSTR AES, V66, P1702, DOI 10.1016/j.bjps.2013.06.057
   Ali B, 2021, J PLAST SURG HAND SU, V55, P162, DOI 10.1080/2000656X.2020.1856672
   Ali B, 2020, SEMIN THORAC CARDIOV, V32, P369, DOI 10.1053/j.semtcvs.2019.12.007
   Bakaeen FG, 2008, AM J SURG, V195, P130, DOI 10.1016/j.amjsurg.2007.04.009
   Bendon CL, 2014, J HAND SURG-AM, V39, P1327, DOI 10.1016/j.jhsa.2014.03.027
   Chen H, 2016, J ORTHOP SURG RES, V11, DOI 10.1186/s13018-016-0480-0
   Chuang MJ, 2015, ARTHROSCOPY, V31, P1702, DOI 10.1016/j.arthro.2015.01.029
   Edwin J, 2018, EFORT OPEN REV, V3, P471, DOI 10.1302/2058-5241.3.170078
   Jang YR, 2019, INFECT DIS-NOR, V51, P694, DOI 10.1080/23744235.2019.1639810
   Joethy J, 2012, ARCH PLAST SURG-APS, V39, P643, DOI 10.5999/aps.2012.39.6.643
   Kachala SS, 2016, ANN THORAC SURG, V101, P2155, DOI 10.1016/j.athoracsur.2016.01.054
   McAninch SA, 2018, J EMERG MED, V54, P229, DOI 10.1016/j.jemermed.2017.11.026
   Mook WR, 2015, J BONE JOINT SURG AM, V97A, P957, DOI 10.2106/JBJS.N.00784
   Murga A, 2017, J THORAC DIS, V9, P1503, DOI 10.21037/jtd.2017.05.76
   Nusselt T, 2011, ARCH ORTHOP TRAUM SU, V131, P319, DOI 10.1007/s00402-010-1178-0
   Phadnis J, 2016, J SHOULDER ELB SURG, V25, P304, DOI 10.1016/j.jse.2015.08.002
   Pothini T, 2024, EUR J CARDIO-THORAC, V65, DOI 10.1093/ejcts/ezae128
   Puri V, 2011, ANN THORAC SURG, V91, P257, DOI 10.1016/j.athoracsur.2010.07.112
   Raymond D, 2014, SURG CLIN N AM, V94, P1283, DOI 10.1016/j.suc.2014.08.004
   Ross JJ, 2004, MEDICINE, V83, P139, DOI 10.1097/01.md.0000126761.83417.29
   Schreiner W, 2020, ANN THORAC SURG, V110, P1722, DOI 10.1016/j.athoracsur.2020.04.037
   Tanaka Yoshihito, 2016, J Med Case Rep, V10, P69, DOI [10.1186/s13256-016-0856-0, 10.1186/s13256-016-0856-0]
   Tasnim S, 2020, J THORAC DIS, V12, P4418, DOI 10.21037/jtd-20-761
   Thompson MA, 2018, J EMERG MED, V55, P128, DOI 10.1016/j.jemermed.2018.02.044
   von Glinski Alexander, 2019, J Clin Orthop Trauma, V10, P406, DOI [10.1016/j.jcot.2018.05.001, 10.1016/j.jcot.2018.05.001]
NR 26
TC 1
Z9 2
U1 0
U2 0
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD MAR 11
PY 2025
VL 14
IS 6
AR 1893
DI 10.3390/jcm14061893
PG 10
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 0QA0I
UT WOS:001453273400001
PM 40142700
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Barry, IP
   Turley, LP
   Gwilym, BL
   Bosanquet, DC
   Richards, T
AF Barry, Ian Patrick
   Turley, Luke P.
   Gwilym, Brenig L.
   Bosanquet, David C.
   Richards, Toby
TI Impact of closed-incision negative pressure wound dressings on surgical
   site infection following groin incisions in vascular surgery; a
   single-centre experience
SO VASCULAR
LA English
DT Article
DE Closed-incisions negative; pressure wound therapy; closed-incision
   negative pressure wound therapy; vascular; vascular surgery; surgical
   site infection; groin incision
ID LOWER-EXTREMITY BYPASS; RISK-FACTORS; THERAPY; READMISSION; PREVENTION;
   TRENDS
AB Objectives: Surgical site infection (SSI) is a common complication in vascular surgery, and is associated with increased patient morbidity, readmission and reintervention. The aim of this study was to assess the impact of closed-incision negative pressure wound therapy (CiNPWT) upon rate of SSI and length of hospital stay.
   Methods: This study was reported in line with the STROBE guidelines. We assessed the baseline incidence of SSI from a 12-month retrospective cohort and, following a change in practice intervention with CiNPWT, compared to a 6-month prospective cohort. The primary endpoint was incidence of SSI (according to CDC-NHSN guidelines) while secondary endpoints included length of hospital stay, readmission, reintervention and Days Alive and Out of Hospital (DAOH) to 90-days.
   Results: A total of 127 groin incisions were performed: 76 (65 patients) within the retrospective analysis and 51 (42 patients) within the prospective analysis (of whom 69% received CiNPWT). The primary endpoint of SSI was seen in 21.1% of the retrospective cohort and 9.8% of the prospective cohort (p =.099). Readmission was found to be significantly associated with the retrospective cohort (p =.016) while total admission (inclusive of re-admission) was significantly longer in those in the retrospective cohort (p =.013). DAOH-90 was 83 days (77-85) following introduction of the CiNPWT protocol as compared to the retrospective cohort (77 days (64-83), p =.04).
   Conclusion: Introduction of CiNPWT was associated with a reduced length of hospital stay and improved DAOH-90. Further trials on CINPWT should include patient-centred outcomes and healthcare cost analysis.
C1 [Barry, Ian Patrick; Richards, Toby] Fiona Stanley Hosp, Dept Vasc Surg, Perth, WA, Australia.
   [Turley, Luke P.] Sir Charles Gairdner Hosp, Dept Gen Surg, Nedlands, WA, Australia.
   [Gwilym, Brenig L.; Bosanquet, David C.] Aneurin Bevan Univ Hlth Board, Dept Vasc Surg, Newport, Gwent, Wales.
   [Richards, Toby] Univ Western Australia, Perth, WA, Australia.
C3 South Metropolitan Health Service; Fiona Stanley Fremantle Hospitals
   Group; Fiona Stanley Hospital; Sir Charles Gairdner Hospital; University
   of Western Australia; University of Western Australia
RP Barry, IP (通讯作者)，Fiona Stanley Hosp, Dept Vasc Surg, 11 Robin Warren Dr, Murdoch, WA 6010, Australia.
EM Ian.Barry@health.wa.gov.au
RI Gwilym, Brenig/HJA-5869-2022; Richards, Toby/K-6547-2013; Bosanquet,
   David/AAB-1557-2022
OI Richards, Toby/0000-0001-9872-4653; Barry, Ian/0000-0002-2414-9315;
   Bosanquet, David/0000-0003-2304-0489
CR Bell M, 2019, ECLINICALMEDICINE, V11, P18, DOI 10.1016/j.eclinm.2019.04.011
   Benrashid E, 2020, J VASC SURG, V71, P896, DOI 10.1016/j.jvs.2019.05.066
   Centers for Disease Control and Prevention (CDC), 2017, NAT HEALTHC SAF NETW
   Damrauer SM, 2015, J VASC SURG, V62, P1192, DOI 10.1016/j.jvs.2015.06.213
   Dua A, 2014, J VASC SURG, V60, P1635, DOI 10.1016/j.jvs.2014.08.072
   Engelhardt M, 2018, INT WOUND J, V15, P327, DOI 10.1111/iwj.12848
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Gwilym BL, 2019, INT J SURG PROTOC, V16, P9, DOI 10.1016/j.isjp.2019.06.001
   Horch RE, 2015, J WOUND CARE, V24, P21, DOI 10.12968/jowc.2015.24.Sup4b.21
   Inui T, 2015, SEMIN VASC SURG, V28, P201, DOI 10.1053/j.semvascsurg.2016.02.002
   Kim JH, 2019, J ARTHROPLASTY, V34, P2804, DOI 10.1016/j.arth.2019.06.020
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Pinkney TD, 2013, BMJ-BRIT MED J, V347, DOI 10.1136/bmj.f4305
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Sahebally SM, 2018, JAMA SURG, V153, DOI 10.1001/jamasurg.2018.3467
   Stewart AH, 2007, J VASC SURG, V46, P148, DOI 10.1016/j.jvs.2007.02.065
   Turtiainen J, 2010, SCAND J SURG, V99, P167, DOI 10.1177/145749691009900312
   Uchino M, 2013, INT SURG, V98, P24, DOI 10.9738/CC83.1
   Vogel TR, 2010, J VASC SURG, V51, P122, DOI 10.1016/j.jvs.2009.08.006
   von Elm E, 2007, PLOS MED, V4, P1623, DOI [10.1371/journal.pmed.0040296, 10.1371/journal.pmed.0040297]
   Wee IJY, 2019, EUR J VASC ENDOVASC, V58, P446, DOI 10.1016/j.ejvs.2018.12.021
   Wiseman JT, 2015, J VASC SURG, V62, P1023, DOI 10.1016/j.jvs.2015.04.453
   Worth LJ, 2015, INFECT CONT HOSP EP, V36, P409, DOI 10.1017/ice.2014.70
   Zhang JQ, 2014, J VASC SURG, V59, P1331, DOI 10.1016/j.jvs.2013.12.032
NR 27
TC 3
Z9 4
U1 0
U2 1
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1708-5381
EI 1708-539X
J9 VASCULAR
JI Vascular
PD DEC
PY 2023
VL 31
IS 6
BP 1128
EP 1133
AR 17085381221111007
DI 10.1177/17085381221111007
EA JUN 2022
PG 6
WC Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA Y8QU5
UT WOS:000821085500001
PM 35759405
DA 2026-07-24
ER

PT J
AU Karakol, P
   Bozkurt, M
AF Karakol, Percin
   Bozkurt, Mehmet
TI Recent strategic approach in postburn extremity scars and contractures
SO JOURNAL OF PLASTIC SURGERY AND HAND SURGERY
LA English
DT Article
DE Burn contractures; dermal scaffolds; negative pressure wound therapy;
   cellular therapy; platelet-rich plasma; fat graft
ID NEGATIVE-PRESSURE DRESSINGS; THICKNESS SKIN-GRAFTS; PLATELET-RICH
   PLASMA; DERMAL SUBSTITUTION; RECONSTRUCTIVE SURGERY; ASSESSMENT SCALE;
   FAT INJECTION; BURN SCAR; CLOSURE; MANAGEMENT
AB This study aims to present the outcomes from current alternative treatment modalities combined with the conventional techniques used in the treatment of burn contractures. Twenty-nine patients were included in the study. Patients were divided into three groups according to the severity of contractures: 1- mild, 2- moderate, and 3- severe. Skin defects that occurred following the incision and scar contracture release were closed with a collagen-elastin acellular dermal matrix (ADM). The split-thickness skin graft was evenly placed on the ADM and fixed with absorbable sutures. The grafts were closed with NPWT (negative pressure wound therapy system) dressings. In platelet-rich plasma (PRP) mild cases as well as moderate and severe PRP cases, stem cell and fat injection were applied. PRP injection was applied to the scar base before the contracture; fat injection and stem cells were applied at the 3rd and 6th months. Preoperative and postoperative range of motion (ROM), Patient and Observer Scars Evaluation Scale (POSAS), and histopathological scores were evaluated. There was a statistically significant decrease in postoperative POSAS scores (p < .05) and a significant increase in the ROM score (p < .05). Histopathological examination revealed an increased postoperative collagen accumulation and organization, increased vascularization, decreased scar tissue thickness and increased subcutaneous tissue thickness. There was no difference in treatment outcomes between the groups.
   Based on the current findings, we conclude that ADM, stem cell-rich fat grafting, and PRP therapies combined with conventional methods could satisfactorily improve functional outcomes in the repair of burn contractures.
C1 [Karakol, Percin; Bozkurt, Mehmet] Hlth Sci Univ, Dept Plast Reconstruct & Aesthet Surg, Bagcilar Educ & Training Hosp, TR-3400 Istanbul, Turkey.
C3 Istanbul Bagcilar Training & Research Hospital
RP Karakol, P (通讯作者)，Hlth Sci Univ, Dept Plast Reconstruct & Aesthet Surg, Bagcilar Educ & Training Hosp, TR-3400 Istanbul, Turkey.
EM ppercin@gmail.com
RI BOZKURT, Mehmet/KFR-6152-2024
CR Alser Osaid H, 2018, Scars Burn Heal, V4, p2059513118808773, DOI [10.1177/2059513118808773, 10.1177/2059513118808773]
   Askari M, 2011, PLAST RECONSTR SURG, V127, P1593, DOI 10.1097/PRS.0b013e31820a6511
   Avery C, 2000, INT J ORAL MAX SURG, V29, P198, DOI 10.1016/S0901-5027(00)80092-2
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Bloemen MCT, 2012, WOUND REPAIR REGEN, V20, P797, DOI 10.1111/j.1524-475X.2012.00845.x
   Bloemen MCT, 2010, PLAST RECONSTR SURG, V125, P1450, DOI 10.1097/PRS.0b013e3181d62b08
   Bozkurt M, 2017, BURNS, V43, P445, DOI 10.1016/j.burns.2016.04.022
   Busche MN, 2018, J BURN CARE RES, V39, P516, DOI 10.1093/jbcr/irx009
   Choi JY, 2014, ARCH PLAST SURG-APS, V41, P337, DOI 10.5999/aps.2014.41.4.337
   Chou TD, 2001, PLAST RECONSTR SURG, V108, P378, DOI 10.1097/00006534-200108000-00015
   Coleman S R, 1998, Aesthet Surg J, V18, P388, DOI 10.1016/S1090-820X(98)70098-6
   Demircan M, 2015, BURNS, V41, P1268, DOI 10.1016/j.burns.2015.01.007
   Draaijers LJ, 2004, PLAST RECONSTR SURG, V113, P1960, DOI 10.1097/01.PRS.0000122207.28773.56
   Fufa DT, 2014, J HAND SURG-AM, V39, P1869, DOI 10.1016/j.jhsa.2014.03.018
   Gaspar Krisztian, 2006, Int Wound J, V3, P51, DOI 10.1111/j.1742-4801.2006.00175.x
   Gassling VLW, 2009, J CRANIOFAC SURG, V20, P423, DOI 10.1097/SCS.0b013e31819b96c9
   Greenwood John E, 2011, Eplasty, V11, pe16
   Haik J, 2012, J DRUGS DERMATOL, V11, P866
   Hanasono MM, 2007, ANN PLAS SURG, V58, P573, DOI 10.1097/01.sap.0000237638.93453.66
   Haslik W, 2007, BURNS, V33, P364, DOI 10.1016/j.burns.2006.07.021
   Haslik W, 2010, J PLAST RECONSTR AES, V63, P360, DOI 10.1016/j.bjps.2008.09.026
   Hur GY, 2014, BURNS, V40, P1497, DOI 10.1016/j.burns.2014.08.007
   Hur J, 2007, CIRCULATION, V116, P1671, DOI 10.1161/CIRCULATIONAHA.107.694778
   Isago T, 2003, J DERMATOL, V30, P673, DOI 10.1111/j.1346-8138.2003.tb00456.x
   Jung YG, 2008, STEM CELLS, V26, P2042, DOI 10.1634/stemcells.2008-0149
   Kamolz LP, 2009, BURNS, V35, P327, DOI 10.1016/j.burns.2008.08.004
   Kaux JF, 2011, PATHOL BIOL, V59, P275, DOI 10.1016/j.patbio.2010.11.002
   Kim EK, 2007, ANN PLAS SURG, V58, P536, DOI 10.1097/01.sap.0000245121.32831.47
   Klinger M, 2008, AESTHET PLAST SURG, V32, P465, DOI 10.1007/s00266-008-9122-1
   Kurita J, 2011, ANN THORAC SURG, V92, P837, DOI 10.1016/j.athoracsur.2011.04.084
   Kusumanto Yoka H., 2003, Angiogenesis, V6, P283, DOI 10.1023/B:AGEN.0000029415.62384.ba
   Kuzucu I, 2017, J CRANIOFAC SURG, V28, pE299, DOI 10.1097/SCS.0000000000003664
   Landau AG, 2008, ANN PLAS SURG, V60, P661, DOI 10.1097/SAP.0b013e318146c288
   Locke MB, 2008, ANN PLAS SURG, V60, P98, DOI 10.1097/SAP.0b013e318038f74c
   Matsumoto T, 2006, AM J PATHOL, V169, P1440, DOI 10.2353/ajpath.2006.060064
   Min JH, 2014, ARCH PLAST SURG-APS, V41, P330, DOI 10.5999/aps.2014.41.4.330
   Moiemen NS, 2010, BURNS, V36, P764, DOI 10.1016/j.burns.2010.04.011
   NAKAYAMA Y, 1990, PLAST RECONSTR SURG, V86, P1216, DOI 10.1097/00006534-199012000-00031
   Fraga MFP, 2010, J PLAST RECONSTR AES, V63, pE818, DOI 10.1016/j.bjps.2010.07.003
   Ryssel H, 2008, BURNS, V34, P93, DOI 10.1016/j.burns.2007.01.018
   Ryssel H, 2010, BURNS, V36, P1107, DOI 10.1016/j.burns.2009.12.002
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Scimeca Christy L, 2010, J Diabetes Sci Technol, V4, P1121
   Stokes TH, 2006, ANN PLAS SURG, V56, P649, DOI 10.1097/01.sap.0000202826.61782.c9
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   Tang A T, 2000, J Wound Care, V9, P229
   van der Wal MBA, 2012, PLAST RECONSTR SURG, V129, p172E, DOI 10.1097/PRS.0b013e3182362e9b
   van Zuijlen PPM, 2000, PLAST RECONSTR SURG, V106, P615, DOI 10.1097/00006534-200009030-00014
   Wainwright DJ, 2009, CLIN PLAST SURG, V36, P687, DOI 10.1016/j.cps.2009.05.009
   WAINWRIGHT DJ, 1995, BURNS, V21, P243, DOI 10.1016/0305-4179(95)93866-I
   Xie Y, 2010, J PLAST RECONSTR AES, V63, P270, DOI 10.1016/j.bjps.2008.11.016
   Yim H, 2010, BURNS, V36, P322, DOI 10.1016/j.burns.2009.10.018
NR 52
TC 8
Z9 11
U1 0
U2 3
PU Medical Journal Sweden AB
PI Uppsala
PA Kungsngsvgen 27St, Uppsala, SWEDEN
SN 2000-656X
EI 2000-6764
J9 J PLAST SURG HAND SU
JI J. Plast. Surg. Hand Surg.
PD JUN 1
PY 2021
VL 55
IS 3
BP 153
EP 161
DI 10.1080/2000656X.2020.1856670
EA NOV 2020
PG 9
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA SO9KZ
UT WOS:000598547600001
PM 33315507
OA gold
DA 2026-07-24
ER

PT J
AU Dumville, JC
   Munson, C
AF Dumville, Jo C.
   Munson, Christopher
TI Negative pressure wound therapy for partial-thickness burns
SO COCHRANE DATABASE OF SYSTEMATIC REVIEWS
LA English
DT Review
DE Occlusive Dressings; Wound Healing; Burns [classification; pathology;
   therapy]; Randomized Controlled Trials as Topic; Suction
   [instrumentation; methods]; Humans
ID SUBATMOSPHERIC PRESSURE; PROGRESSION; PATIENT
AB Background
   A burn wound is a complex and evolving injury, with both local and systemic consequences. Burn treatments include a variety of dressings, as well as newer strategies, such as negative pressure wound therapy (NPWT), which, by means of a suction force that drains excess fluids from the burn, tries to promote the wound healing process and minimise progression of the burn wound.
   Objectives
   To assess the effectiveness of NPWT for people with partial-thickness burns.
   Search methods
   For this third update we searched the Cochrane Wounds Group Specialised Register (searched 18 May 2012); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 5); Ovid MEDLINE (2010 to May Week 2 2012); Ovid MEDLINE (In-Process & Other Non-Indexed Citations 17 May 2012); Ovid EMBASE (2010 to 2012 Week 19); and EBSCO CINAHL (2010 to 16 May 2012).
   Selection criteria
   All randomised controlled trials (RCTs) and controlled clinical trials (CCTs) that evaluated the safety and effectiveness of NPWT for partial-thickness burns.
   Data collection and analysis
   Two review authors used standardised forms, and extracted the data independently. We assessed each trial for risk of bias, and resolved differences by discussion.
   Main results
   One RCT, that was an interim report, satisfied the inclusion criteria. We undertook a narrative synthesis of results, as the absence of data and poor reporting precluded us from carrying out any formal statistical analysis. The trial was at high risk of bias.
   Authors' conclusions
   There was not enough evidence available to permit any conclusions to be drawn regarding the use of NPWT for treatment of partial-thickness burn wounds.
C1 [Dumville, Jo C.] Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England.
   [Munson, Christopher] St Johns Hosp Howden, Plast Surg Dept, Livingston, Scotland.
C3 University of York - UK
RP Dumville, JC (通讯作者)，Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England.
EM jd34@york.ac.uk
RI Dumville, Jo/O-7867-2014
OI Dumville, Jo/0000-0002-6546-3685
FU NIHR/Department of Health (England), (Cochrane Wounds Group), UK
FX External sources NIHR/Department of Health (England), (Cochrane Wounds
   Group), UK.
CR Adamkova M, 2005, Acta Chir Plast, V47, P24
   [Anonymous], REVIEW MANAGER REVMA
   [Anonymous], CLIN EVIDENCE
   [Anonymous], OSTOMY WOUND MANAGEM
   [Anonymous], MANAGING THE BURN WO
   [Anonymous], COCHRANE HDB SYSTEMA
   [Anonymous], 2ND WORLD UNION OF W
   [Anonymous], OSTOMY WOUND MANAGEM
   [Anonymous], REPORT NO 37
   [Anonymous], COMPARISON OF PRICES
   Atiyeh BS, 2005, WORLD J SURG, V29, P131, DOI 10.1007/s00268-004-1082-2
   Banwell P E, 1999, J Wound Care, V8, P79
   Banwell Paul E, 2004, Ostomy Wound Manage, V50, p9S
   Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   BOYKIN JV, 1980, PLAST RECONSTR SURG, V66, P191, DOI 10.1097/00006534-198008000-00002
   Brigham Peter A., 1996, Journal of Burn Care and Rehabilitation, V17, P95, DOI 10.1097/00004630-199603000-00003
   Deeks JJ, 2002, STAT MED, V21, P1575, DOI 10.1002/sim.1188
   DEMLING RH, 1979, SURGERY, V85, P339
   Haslik W, 2004, ZBL CHIR, V129, pS62, DOI 10.1055/s-2004-822603
   Higgins JPT, 2003, BMJ-BRIT MED J, V327, P557, DOI 10.1136/bmj.327.7414.557
   Johnson R Michael, 2003, Adv Skin Wound Care, V16, P178, DOI 10.1097/00129334-200307000-00010
   Kamolz LP, 2004, BURNS, V30, P253, DOI 10.1016/j.burns.2003.12.003
   Moisidis E, 2004, PLAST RECONSTR SURG, V114, P917, DOI 10.1097/01.PRS.0000133168.57199.E1
   Nugent N, 2005, BURNS, V31, P390, DOI 10.1016/j.burns.2004.10.019
   Schintler M, 2005, BURNS, V31, P1050, DOI 10.1016/j.burns.2005.03.003
   Schrank C, 2004, ZBL CHIR, V129, pS59, DOI 10.1055/s-2004-822605
   Sheridan RL, 2002, CRIT CARE MED, V30, pS500, DOI 10.1097/00003246-200211001-00015
   Subrahmanyam M, 1998, BURNS, V24, P157, DOI 10.1016/S0305-4179(97)00113-7
   The Scottish Intercollegiate Guidelines Network (SIGN), Scottish Intercollegiate Guidelines Network Search Filters 2015
   Tierney JF, 2007, TRIALS, V8, DOI 10.1186/1745-6215-8-16
   Ubbink DT, 2008, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001898.pub2
   VILLANUEVA E, 2004, COCHRANE DB SYST REV, DOI DOI 10.1002/14651858.CD004727.PUB2
   Wasiak J, 2007, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006215
   YOUN YK, 1992, WORLD J SURG, V16, P30, DOI 10.1007/BF02067111
NR 34
TC 7
Z9 12
U1 1
U2 4
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1469-493X
EI 1361-6137
J9 COCHRANE DB SYST REV
JI Cochrane Database Syst Rev.
PY 2012
IS 12
AR CD006215
DI 10.1002/14651858.CD006215.pub3
PG 21
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 053FL
UT WOS:000312256300032
PM 23235626
DA 2026-07-24
ER

PT J
AU Vélez-Palafox, M
   Ponce-Damián, LD
   Márquez-Gutiérrez, EA
   González-Torres, M
AF Velez-Palafox, Mario
   Ponce-Damian, Leonardo David
   Marquez-Gutierrez, Erik Agustin
   Gonzalez-Torres, Maykel
TI Neck reconstruction in burn sequelae: A comparison of full-thickness
   skin grafts with traditional tie-over versus negative pressure wound
   therapy for both recipient site preparation and graft fixation
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Article
DE Burn sequelae; Full-thickness graft; Negative wound therapy; Neck
   reconstruction
ID HEAD; DRESSINGS; EFFICACY
AB Background: Neck reconstruction for burn sequelae can be effectively achieved through release procedures and lower abdomen skin transplantation. This article describes cases in which full-thickness skin grafts (FTSGs) from the lower abdomen were used as donor areas. Although the benefits of negative pressure wound therapy (NPWT) for graft integration are known, its dual use for recipient site preparation and intraoperative graft fixation, specifically in the neck, has been scarcely described. This study evaluates both applications of NPWT-preoperative wound bed optimization and intraoperative graft fixation-highlighting their combined impact on graft take and patient outcomes. Methods: Patients treated at a referral burn center between March 2021 and October 2023 with severe neck contractures underwent scar release and FTSG transplantation. Two techniques for graft fixation were compared: the traditional tie-over method and NPWT. Graft integration rates, necrosis percentages, and postoperative complications were assessed. Results: The study included six patients (tie-over group: 2; NPWT group: 4). The NPWT group demonstrated clinically favorable graft integration rates (92.5 %) and lower necrosis rates (7.5 %) compared with the tie-over group (76.5 % and 23.5 %, respectively). The NPWT technique also resulted in shorter hospital stays and fewer complications. Conclusions: The combined use of NPWT for recipient site preparation and intraoperative graft fixation clinically improves graft integration and reduces complications in neck burn reconstruction. These findings suggest that NPWT should be considered a standard of care in settings where resources allow.
C1 [Velez-Palafox, Mario] Natl Inst Rehabil, Natl Ctr Res & Care Burns, Div Head Plast & Reconstruct Surg, Mexico City, Mexico.
   [Velez-Palafox, Mario] Univ Nacl Autonoma Mexico, Fac Med, Grad Studies Div, Mexico City, Mexico.
   [Ponce-Damian, Leonardo David; Marquez-Gutierrez, Erik Agustin] Natl Ctr Res & Care Burns, Natl Inst Rehabil, Div Plast & Reconstruct Surg, Mexico City, Mexico.
   [Gonzalez-Torres, Maykel] UNAM, Fac Estudios Super Cuautitlan, Dept Ciencias Quim, Ave 1ro Mayo S-N, Cuautitlan 54740, Estado De Mexic, Mexico.
C3 Universidad Nacional Autonoma de Mexico; Universidad Nacional Autonoma
   de Mexico
RP Vélez-Palafox, M (通讯作者)，Univ Nacl Autonoma Mexico, Fac Med, Grad Studies Div, Mexico City, Mexico.
EM mariovelez@hotmail.com; maykel.gonzalez@conahcyt.mx
RI ; González Torres, Maykel/O-4924-2019
OI MÁRQUEZ-GUTIÉRREZ, ERIK/0009-0004-1651-0256; Velez-Palafox,
   Mario/0009-0009-4275-7590; González Torres, Maykel/0000-0003-3899-4410
CR Adant JP, 1998, ACTA CHIR BELG, V98, P5
   Baek S, 2023, MEDICINA-LITHUANIA, V59, DOI 10.3390/medicina59071342
   Cao XL, 2022, PLAST RECONSTR SURG, V150, P1341, DOI 10.1097/PRS.0000000000009704
   Donelan MB, 2018, Total burn care, P1
   Engrav L H., 1997, Opin Tech Plast Reconstr Surg, V4, P53, DOI DOI 10.1016/S1071-0949(97)80009-1
   Ghorbel I, 2019, CASE REP SURG, V2019, DOI 10.1155/2019/9879163
   Granzow JW, 2013, OTOLARYNG HEAD NECK, V148, P941, DOI 10.1177/0194599813476670
   Gur E, 2024, MICROSURG, V44, DOI 10.1002/micr.31175
   Hassan S, 2014, BURNS TRAUMA, V2, DOI 10.4103/2321-3868.130193
   Hoogewerf CJ, 2013, BURNS, V39, P1184, DOI 10.1016/j.burns.2013.03.006
   Jang Y, 2025, AGING MENT HEALTH, V29, P542, DOI 10.1080/13607863.2024.2407586
   Jiang ZY, 2021, BURNS, V47, P747, DOI 10.1016/j.burns.2021.02.012
   Kim EK, 2007, ANN PLAS SURG, V58, P536, DOI 10.1097/01.sap.0000245121.32831.47
   Kondo A, 2021, PRS-GLOB OPEN, V9, DOI 10.1097/GOX.0000000000003404
   Landau AG, 2008, ANN PLAS SURG, V60, P661, DOI 10.1097/SAP.0b013e318146c288
   Lau B, 2011, Operative Techniques in Otolaryngology-Head and Neck Surgery, V22, P24, DOI [10.1016/j.otot.2010.08.004, DOI 10.1016/J.OTOT.2010.08.004]
   Lin PY, 2018, LARYNGOSCOPE, V128, P2478, DOI 10.1002/lary.27169
   Mir A, 2019, LARYNGOSCOPE, V129, P671, DOI 10.1002/lary.27262
   Ninkovic M, 2004, PLAST RECONSTR SURG, V113, P61, DOI 10.1097/01.PRS.0000090726.45594.6B
   Pradier JP, 2011, ANN CHIR PLAST ESTH, V56, P417, DOI 10.1016/j.anplas.2011.07.006
   Prakash S, 2015, BURNS, V41, P1627, DOI 10.1016/j.burns.2015.03.011
   ROBSON MC, 1992, WORLD J SURG, V16, P87, DOI 10.1007/BF02067119
   Rosenthal EL, 2005, HEAD NECK-J SCI SPEC, V27, P970, DOI 10.1002/hed.20265
   Sabapathy SR, 2022, PLAST RECONSTR SURG, V150, p1326E, DOI 10.1097/PRS.0000000000009690
   Shen X, 2019, WOUNDS, V31, P213
   Shimizu Ruka, 2012, Plast Surg Int, V2012, P563493, DOI 10.1155/2012/563493
   Stekelenburg CM, 2017, BURNS TRAUMA, V5, DOI 10.1186/s41038-017-0071-2
   Strub GM, 2013, FACIAL PLAST SURG CL, V21, P137, DOI 10.1016/j.fsc.2012.11.005
   Wilson IF, 2000, PLAST RECONSTR SURG, V105, P27, DOI 10.1097/00006534-200001000-00005
   Zhu ZZ, 2016, BURNS TRAUMA, V4, DOI 10.1186/s41038-015-0026-4
NR 30
TC 0
Z9 0
U1 1
U2 1
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0020-1383
EI 1879-0267
J9 INJURY
JI Injury-Int. J. Care Inj.
PD MAY
PY 2025
VL 56
IS 5
AR 112323
DI 10.1016/j.injury.2025.112323
EA MAY 2025
PG 7
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA 3VA8K
UT WOS:001509684400001
PM 40222842
OA hybrid
DA 2026-07-24
ER

PT J
AU Jiang, TT
   Su, YH
   Wu, YK
   Li, C
   Sun, TK
   Li, YH
   Ji, YY
   Wang, ZD
AF Jiang, Tiantian
   Su, Yuanhao
   Wu, Yongke
   Li, Cheng
   Sun, Tingkai
   Li, Yunhao
   Ji, Yuanyuan
   Wang, Zhidong
TI No closure of the linea alba cervicalis reduces complications in
   endoscopic thyroidectomy
SO SCIENTIFIC REPORTS
LA English
DT Article
DE Endoscopic thyroidectomy; Chest-breast; Linea Alba cervicalis;
   Complication; Negative pressure wound therapy (NPWT)
ID PRESSURE WOUND THERAPY; SURGERY; MANAGEMENT; SCARLESS; HEMATOMA; CANCER
AB The benefits of not suturing the linea alba cervicalis and using negative pressure wound therapy after endoscopic thyroidectomy have attracted increasing attention. Therefore, this study aims to determine whether the non-closure of the linea alba cervicalis after endoscopic thyroidectomy can significantly reduce postoperative complications and evaluate the application of NPWT to prevent cavity-related complications. A retrospective analysis was performed. 142 patients were enrolled and divided into two groups, including 71 individuals in the improvement group (no suture of the linea alba cervicalis) and 71 in the conventional group (suture the linea alba cervicalis). Then, the general clinical data and operative indicators were analyzed and compared between the two groups using SPSS 26.0 software. Statistical significance was recognized with P < 0.05. The improvement group showed a lower incidence of neck edema (3/71,4.2% vs. 10/71,14.1%) and a lower score on the Visual Analogue Scale (VAS) 5 days after the operation (3 +/- 1.2 vs. 4 +/- 1.3) between the two groups (P < 0.05), and there is no significant difference in the overall incidence of postoperative complications between the two groups (P>0.05). No closure of the linea alba cervicalis is safe and feasible after endoscopic thyroidectomy via chest-breast approach, with significantly less incidence of neck edema and lower neck discomfort. In addition, NPWT, providing a novel tool to reduce the occurrence of cavity-related complications in current clinical practice, can be used in whether or not to suture the linea alba cervicalis, which is safe and effective.
C1 [Jiang, Tiantian; Su, Yuanhao; Wu, Yongke; Li, Cheng; Sun, Tingkai; Li, Yunhao; Wang, Zhidong] Xi An Jiao Tong Univ, Affiliated Hosp 2, Dept Gen Surg, Xian 710004, Peoples R China.
   [Ji, Yuanyuan] Xi An Jiao Tong Univ, Affiliated Hosp 2, Precis Med Inst, Sci Res Ctr, Xian 710004, Peoples R China.
C3 Xi'an Jiaotong University; Xi'an Jiaotong University
RP Wang, ZD (通讯作者)，Xi An Jiao Tong Univ, Affiliated Hosp 2, Dept Gen Surg, Xian 710004, Peoples R China.; Ji, YY (通讯作者)，Xi An Jiao Tong Univ, Affiliated Hosp 2, Precis Med Inst, Sci Res Ctr, Xian 710004, Peoples R China.
EM jiyuanyuan1234@163.com; xawzd@163.com
RI Su, YuanHao/GQA-9051-2022
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Arora A, 2016, INT J SURG, V25, P38, DOI 10.1016/j.ijsu.2015.11.021
   Åström M, 2023, QUAL LIFE RES, V32, P2719, DOI 10.1007/s11136-023-03411-3
   Atisook R, 2021, J PAIN RES, V14, P1129, DOI 10.2147/JPR.S303305
   Ayandipo OO, 2022, S. Afr. j. surg., V60, P128, DOI [10.17159/2078-5151/sajs3625, 10.17159/2078-5151/SAJS3625]
   Bektasoglu HK, 2019, PAIN RES MANAG, V2019, DOI 10.1155/2019/9392780
   Bjelkaroy MT, 2024, PROG NEURO-PSYCHOPH, V130, DOI 10.1016/j.pnpbp.2023.110925
   Cagney D, 2020, WORLD J SURG, V44, P1526, DOI 10.1007/s00268-019-05335-x
   Chang YW, 2020, ASIAN J SURG, V43, P234, DOI 10.1016/j.asjsur.2019.02.012
   Chinese expert consensus on suture technique, 2021, Chin. J. Practical Surg, V41, P512, DOI [10.19538/j.cjps.issn1005-2208.2021.05.05, DOI 10.19538/J.CJPS.ISSN1005-2208.2021.05.05]
   Dumlu EG, 2016, TURK J SURG, V32, P173, DOI 10.5152/UCD.2015.3138
   Eken MK, 2017, J MATERN-FETAL NEO M, V30, P922, DOI 10.1080/14767058.2016.1190826
   Haugen BR, 2016, THYROID, V26, P1, DOI 10.1089/thy.2015.0020
   Hey C, 2023, EUR ARCH OTO-RHINO-L, V280, P2585, DOI 10.1007/s00405-023-07865-6
   Hey C, 2013, ANTICANCER RES, V33, P4017
   Horch RE, 2020, EXPERT REV MED DEVIC, V17, P139, DOI 10.1080/17434440.2020.1714434
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Jiang WJ, 2020, SURG ENDOSC, V34, P1891, DOI 10.1007/s00464-019-07283-y
   Kapustian V, 2012, AM J OBSTET GYNECOL, V206, DOI 10.1016/j.ajog.2011.07.032
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Kitahara CM, 2016, NAT REV ENDOCRINOL, V12, P646, DOI 10.1038/nrendo.2016.110
   Lalezari S, 2017, INT WOUND J, V14, P649, DOI 10.1111/iwj.12658
   Lee DY, 2016, GLAND SURG, V5, P327, DOI 10.21037/gs.2015.10.01
   Lee JH, 2023, HEAD NECK-J SCI SPEC, V45, P827, DOI 10.1002/hed.27295
   Lee S, 2011, ANN SURG, V253, P1060, DOI 10.1097/SLA.0b013e3182138b54
   Mahoney RC, 2021, J SURG RES, V260, P481, DOI 10.1016/j.jss.2020.11.081
   Man L., 2022, Chin. J. Bases Clin. Gen. Surg, V29, P816
   Maroun CA, 2020, LARYNGOSCOPE, V130, P1349, DOI 10.1002/lary.28269
   Ohgami M, 2000, SURG LAPARO ENDO PER, V10, P1, DOI 10.1097/00019509-200002000-00001
   Pai PS, 2019, J POSTGRAD MED, V65, P72, DOI 10.4103/jpgm.JPGM_91_19
   Pathak A, 2018, PAIN REP, V3, DOI 10.1097/PR9.0000000000000672
   Ping W., 2017, Chin. J. Practical Surg, V37, P1369, DOI [10.19538/j.cjps.issn1005-2208.2017.12.14, DOI 10.19538/J.CJPS.ISSN1005-2208.2017.12.14]
   Poteet SJ, 2021, EXPERT REV MED DEVIC, V18, P151, DOI 10.1080/17434440.2021.1882301
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Senne M, 2018, BJS-BRIT J SURG, V105, P645, DOI 10.1002/bjs.10829
   Sun P, 2020, J LAPAROENDOSC ADV S, V30, P308, DOI 10.1089/lap.2019.0527
   Sung H, 2021, CA-CANCER J CLIN, V71, P209, DOI 10.3322/caac.21660
   Tan CTK, 2008, WORLD J SURG, V32, P1349, DOI 10.1007/s00268-008-9555-3
   Wang CC, 2015, SURG ENDOSC, V29, P192, DOI 10.1007/s00464-014-3658-8
   [王平 Wang Ping], 2018, [中国实用外科杂志, Chinese Journal of Practical Surgery], V38, P635
   Weiss A, 2014, SURGERY, V156, P399, DOI 10.1016/j.surg.2014.03.015
   Xie QP, 2019, ENDOCRINE, V63, P422, DOI 10.1007/s12020-018-01837-1
   Xing ZC, 2021, INT J SURG, V89, DOI 10.1016/j.ijsu.2021.105941
   Yuehua L., 2022, China J. Endoscopy, V28, P34
   Zhang GL, 2021, SURG ENDOSC, V35, P2831, DOI 10.1007/s00464-020-07718-x
   Zhang Y, 2024, HEAD NECK-J SCI SPEC, V46, P1210, DOI 10.1002/hed.27713
NR 47
TC 0
Z9 0
U1 2
U2 5
PU NATURE PORTFOLIO
PI BERLIN
PA HEIDELBERGER PLATZ 3, BERLIN, 14197, GERMANY
SN 2045-2322
J9 SCI REP-UK
JI Sci Rep
PD FEB 7
PY 2025
VL 15
IS 1
AR 4577
DI 10.1038/s41598-025-88873-w
PG 9
WC Multidisciplinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Science & Technology - Other Topics
GA W1W8M
UT WOS:001416570900009
PM 39920252
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Settembre, N
   D'oria, M
   Saba, C
   Bouziane, Z
   Malikov, S
AF Settembre, Nicla
   D'oria, Mario
   Saba, Charbel
   Bouziane, Zakariyae
   Malikov, Serguei
TI Negative Pressure Wound Therapy to Promote Fixation and Remodeling of
   Omental Flap in Patients with Revascularized Limbs: A Case Series
SO ANNALS OF VASCULAR SURGERY
LA English
DT Article
ID FREE TISSUE TRANSFER; COMBINED ARTERIAL RECONSTRUCTION; BYPASS FLAP;
   MANAGEMENT; SALVAGE; FLOW
AB We present our experience with 5 patients with chronic limb threatening ischemia (CLTI) treated with distal revascularization and omental flap coverage. We decided to investigate the efficacy and safety of negative-pressure wound therapy (NPWT) in promoting the fixation and remodeling of the omental flap as there is some evidence in the literature about the optimization of results for skin graft and dermal substitutes. Surgical revascularization was always the first procedure attempted; wound coverage was realized 3-5 days after the primary procedure (omental free-flap in 3 patients and omental flow-through flap in 2 patients). NPWT with small foam at -75 mm Hg was applied on the second postoperative day after flap coverage. Effective remodeling of the flap was defined as the flap overcoming the wound edge no more than 10 mm. Limb salvage rate was 100%; in all the patients, and we observed satisfactory fixation and remodeling of the omental flap after 10-20 days of NPWT, secondary skin grafting within 34 weeks after revascularization, and adequate and complete mobilization within 6 months after hospital discharge. We did not report any relapsing infection nor any recurrent wound up to 2 years of follow-up. Distal revascularization combined with omental free-flap or flow-through flap is highly effective for limb salvage in CLTI patients with complex wounds. NPWT may be an useful adjunct to promote fixation and remodeling of the omental flap before secondary skin grafting. It may reduce secondary issues related to omental flap coverage allowing rapid and satisfactory mobilization of patients.
C1 [Settembre, Nicla; D'oria, Mario; Saba, Charbel; Bouziane, Zakariyae; Malikov, Serguei] Univ Lorraine, Nancy Univ Hosp, Dept Vasc Surg, Nancy, France.
   [Settembre, Nicla; Malikov, Serguei] Univ Lorraine, INSERM 1116, Nancy, France.
C3 CHU de Nancy; Universite de Lorraine; Institut National de la Sante et
   de la Recherche Medicale (Inserm); Universite de Lorraine
RP Settembre, N (通讯作者)，Univ Lorraine, Nancy Univ Hosp, Dept Vasc Surg, 1 Rue Morvan, F-54500 Vandoeuvre Les Nancy, France.
EM nicla.settembre@yahoo.com
RI D'Oria, Mario/AAF-5578-2020
OI D'Oria, Mario/0000-0002-7156-7827; Settembre, Nicla/0000-0003-3107-2771
CR Aboyans V, 2017, EUR J VASC ENDOVASC, V2017, P25
   Anesäter E, 2011, INT WOUND J, V8, P336, DOI 10.1111/j.1742-481X.2011.00790.x
   Apelqvist Jan, 2017, J Wound Care, V26, pS1, DOI [10.12968/jowc.2017.26.sup3.s1, 10.12968/jowc.2017.26.Sup3.S1]
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Borgquist O, 2011, PLAST RECONSTR SURG, V127, P551, DOI 10.1097/PRS.0b013e3181fed52a
   Borgquist O, 2010, PLAST RECONSTR SURG, V125, P502, DOI 10.1097/PRS.0b013e3181c82e1f
   Bovill E, 2008, INT WOUND J, V5, P511, DOI 10.1111/j.1742-481X.2008.00437.x
   De Caridi G, 2016, INT WOUND J, V13, P336, DOI 10.1111/iwj.12301
   Gabriel A, 2009, INT WOUND J, V6, P1, DOI 10.1111/j.1742-481X.2009.00628.x
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Lavery L A, 1996, J Foot Ankle Surg, V35, P528
   Malikov S, 2008, J VASC SURG, V48, P159, DOI 10.1016/j.jvs.2008.02.023
   Malikov S, 2009, ANN VASC SURG, V23, P745, DOI 10.1016/j.avsg.2009.09.002
   Maloney CT Jr, 2003, PLAST RECONSTR SURG, V111, P1899, DOI 10.1097/01.PRS.0000056874.31920.7D
   McCarthy WJ, 1999, J VASC SURG, V29, P814, DOI 10.1016/S0741-5214(99)70208-9
   Noble-Bell G, 2008, INT WOUND J, V5, P233, DOI 10.1111/j.1742-481X.2008.00430.x
   Norgren L, 2007, EUR J VASC ENDOVASC, V33, pS5, DOI 10.1016/j.ejvs.2006.09.024
   O'Connor EJF, 2011, EUR J VASC ENDOVASC, V41, P391, DOI 10.1016/j.ejvs.2010.11.013
   Schuler J, 1999, J VASC SURG, V29, P818
   Settembre N, 2018, SURG RADIOL ANAT, V40, P415, DOI 10.1007/s00276-017-1951-7
   Settembre N, 2014, ANN VASC SURG, V28, P1128, DOI 10.1016/j.avsg.2013.10.003
   Tukiainen E, 2006, ANN SURG, V244, P949, DOI 10.1097/01.sla.0000247985.45541.e8
NR 22
TC 3
Z9 5
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD OCT
PY 2018
VL 52
AR 313.e5
DI 10.1016/j.avsg.2018.03.006
PG 4
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA GS8RN
UT WOS:000443980600044
PM 29777840
DA 2026-07-24
ER

PT J
AU Wang, GQ
   Li, ZR
   Li, TT
   Wang, S
   Zhang, LH
   Zhang, LC
   Tang, PF
AF Wang, Guoqi
   Li, Zhirui
   Li, Tongtong
   Wang, Song
   Zhang, Lihai
   Zhang, Licheng
   Tang, Peifu
TI Negative-Pressure Wound Therapy in a Pseudomonas
   aeruginosa Infection Model
SO BIOMED RESEARCH INTERNATIONAL
LA English
DT Article
ID RABBIT EAR MODEL; STAPHYLOCOCCUS-AUREUS; BACTERIAL BIOFILMS; IN-VIVO;
   SKIN; VIRULENCE; ELASTASE; GROWTH; MECHANISMS; STRATEGIES
AB Background. Negative-pressure wound therapy (NPWT) is an effective strategy for the management of contaminated wounds, including those infected by Pseudomonas aeruginosa. We hypothesized that NPWT would reduce virulence factors as well as biofilm components and inhibit virulence-regulated gene expression in a model of P. aeruginosa wound infection. Methods. Wounds were created in anesthetized rabbits and P. aeruginosa was inoculated to the wound surface for 24h. Wounds were treated with either NPWT or a sterile gauze dressing. Virulence factors including exotoxin A, rhamnolipid, and elastase were quantified by the enzymelinked immunosorbent assay, orcinol, and elastin-Congo red methods, respectively. A biofilm component, eDNA, was quantified using a commercial kit. Virulence-regulated genes were determined by quantitative real-time polymerase chain reaction (RT-PCR). Biofilms were observed in vivo by staining with concanavalin A conjugated to Alexa Fluor (R) 647. Results. NPWT was more effective than the control treatment in reducing virulence factors and bacteria counts in vivo. A biofilm component, eDNA, was less abundant in the NPWT group. The results of the RT-PCR indicated that the expression levels of P. aeruginosa virulence-regulated genes and quorum-sensing population density-dependent systems were significantly inhibited by NPWT treatment. Conclusion. NPWT reduced bacteria counts, virulence factors, and eDNA in a P. aeruginosa wound infection model in vivo. These beneficial effects are likely to be related to the reduced expression of virulence-regulated genes and the drainage induced by NPWT treatment, These findings may help clinicians to obtain a better understanding of the mechanism of NPWT for the treatment of infected wounds.
C1 [Wang, Guoqi; Li, Zhirui; Zhang, Lihai; Zhang, Licheng; Tang, Peifu] Chinese Peoples Liberat Army Gen Hosp, Dept Orthoped, 28 Fuxing Rd, Beijing 100853, Peoples R China.
   [Li, Tongtong] Tianjin Hosp, Dept Orthoped, 406 Jiefangnan Rd, Tianjin 300211, Peoples R China.
   [Wang, Song] Nankai Univ, Med Coll, Tianjin 300071, Peoples R China.
C3 Chinese People's Liberation Army General Hospital; Tianjin University;
   Nankai University
RP Zhang, LC; Tang, PF (通讯作者)，Chinese Peoples Liberat Army Gen Hosp, Dept Orthoped, 28 Fuxing Rd, Beijing 100853, Peoples R China.
EM zhanglcheng218@126.com; pftang301@163.com
RI ; Li, Zhirui/OJT-0490-2025
OI Tang, Peifu/0000-0003-4279-1704; 
FU National Natural Science Foundation of China [81472112]
FX This study was supported by the National Natural Science Foundation of
   China (Grant no. 81472112)
CR Akers KS, 2014, BMC INFECT DIS, V14, DOI 10.1186/1471-2334-14-190
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Bjarnsholt T, 2008, WOUND REPAIR REGEN, V16, P2, DOI 10.1111/j.1524-475X.2007.00283.x
   Blum ML, 2012, J ORTHOP TRAUMA, V26, P499, DOI 10.1097/BOT.0b013e31824133e3
   Boles BR, 2011, TRENDS MICROBIOL, V19, P449, DOI 10.1016/j.tim.2011.06.004
   Chiang N, 2017, J VASC SURG, V66, P564, DOI 10.1016/j.jvs.2017.02.050
   Cooper RA, 2014, J WOUND CARE, V23, P570, DOI 10.12968/jowc.2014.23.11.570
   Costerton JW, 1999, SCIENCE, V284, P1318, DOI 10.1126/science.284.5418.1318
   Glass GE, 2017, J PLAST RECONSTR AES, V70, P1028, DOI 10.1016/j.bjps.2017.05.027
   Guoqi W., A VANLEEUWENHOEK J M
   Heggers John P., 1992, Journal of Burn Care and Rehabilitation, V13, P512, DOI 10.1097/00004630-199209000-00003
   James GA, 2008, WOUND REPAIR REGEN, V16, P37, DOI 10.1111/j.1524-475X.2007.00321.x
   Kanno E, 2010, EXP DERMATOL, V19, P154, DOI 10.1111/j.1600-0625.2009.00931.x
   Kantak NA, 2017, CLIN PLAST SURG, V44, P671, DOI 10.1016/j.cps.2017.02.023
   Kaufmann GF, 2011, METHODS MOL BIOL, V692, P299, DOI 10.1007/978-1-60761-971-0_22
   Lalliss SJ, 2010, J ORTHOP TRAUMA, V24, P598, DOI 10.1097/BOT.0b013e3181ec45ba
   Lancerotto L, 2012, SEMIN CELL DEV BIOL, V23, P987, DOI 10.1016/j.semcdb.2012.09.009
   Li TT, 2016, EXP THER MED, V11, P769, DOI 10.3892/etm.2016.3008
   Li TT, 2015, ANTON LEEUW INT J G, V108, P907, DOI 10.1007/s10482-015-0545-9
   Liu D., 2017, A VAN LEEUW J MICROB, P1
   Liu Y, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0090494
   Lo Torto F, 2017, INT WOUND J, V14, P909, DOI 10.1111/iwj.12725
   Lyczak JB, 2000, MICROBES INFECT, V2, P1051, DOI 10.1016/S1286-4579(00)01259-4
   Nakagami G, 2011, WOUND REPAIR REGEN, V19, P214, DOI 10.1111/j.1524-475X.2010.00653.x
   Ngo QD, 2012, WOUND REPAIR REGEN, V20, P83, DOI 10.1111/j.1524-475X.2011.00747.x
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Parsek MR, 2003, ANNU REV MICROBIOL, V57, P677, DOI 10.1146/annurev.micro.57.030502.090720
   Pearson JP, 1997, J BACTERIOL, V179, P5756, DOI 10.1128/jb.179.18.5756-5767.1997
   Phillips PL, 2015, INT WOUND J, V12, P469, DOI 10.1111/iwj.12142
   Römling U, 2012, J INTERN MED, V272, P541, DOI 10.1111/joim.12004
   Rumbaugh KP, 1999, INFECT IMMUN, V67, P5854, DOI 10.1128/IAI.67.11.5854-5862.1999
   Schmidtchen A, 2003, MICROB PATHOGENESIS, V34, P47, DOI 10.1016/S0882-4010(02)00197-3
   Seo SG, 2013, EXP MOL MED, V45, DOI 10.1038/emm.2013.129
   Seth AK, 2014, WOUND REPAIR REGEN, V22, P712, DOI 10.1111/wrr.12232
   Seth AK, 2012, PLAST RECONSTR SURG, V129, p262E, DOI 10.1097/PRS.0b013e31823aeb3b
   Shigematsu T, 2007, MICROBIOL IMMUNOL, V51, P1149, DOI 10.1111/j.1348-0421.2007.tb04010.x
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Streubel PN, 2012, J AM ACAD ORTHOP SUR, V20, P564, DOI 10.5435/JAAOS-20-09-564
   Trostrup H, 2013, WOUND REPAIR REGEN, V21, P292, DOI 10.1111/wrr.12016
   Wang GJ, 2016, BIOMED RES INT, V2016, DOI 10.1155/2016/1736024
   Watters C, 2013, MED MICROBIOL IMMUN, V202, P131, DOI 10.1007/s00430-012-0277-7
   Wolcott RD, 2010, J WOUND CARE, V19, P320, DOI 10.12968/jowc.2010.19.8.77709
   Yang YX, 2012, J MICROBIOL, V50, P987, DOI 10.1007/s12275-012-2149-7
   Yusuf E, 2013, WOUND REPAIR REGEN, V21, P677, DOI 10.1111/wrr.12088
NR 44
TC 19
Z9 20
U1 1
U2 20
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 2314-6133
EI 2314-6141
J9 BIOMED RES INT
JI Biomed Res. Int.
PY 2018
VL 2018
AR 9496183
DI 10.1155/2018/9496183
PG 11
WC Biotechnology & Applied Microbiology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biotechnology & Applied Microbiology; Research & Experimental Medicine
GA GG0CI
UT WOS:000432345500001
PM 29862301
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Pavan, F
   Tan, JD
   Gamage, S
   Vu, J
   Cashin, P
   Low, L
   Martin, S
AF Pavan, Fiona
   Tan, Jed
   Gamage, Sankalpa
   Vu, Joseph
   Cashin, Paul
   Low, Liang
   Martin, Sarah
TI Negative pressure dressings and the impact on pain management on
   thoracic incisions in patients undergoing oesophagectomy: a pilot study
SO ANZ JOURNAL OF SURGERY
LA English
DT Article
DE esophagectomy; general surgery; pain; postoperative; thoracotomy
ID WOUND THERAPY; RISK
AB BackgroundPain control is recognised as a crucial post-operative measure for patients undergoing oesophagectomy with a thoracotomy incision for oesophageal cancer, where ineffective breathing due to pain is directly correlated with increased morbidity. The analgesic benefits of negative pressure wound therapy (NPWT) appear to be a relatively new and emerging finding. This pilot study aims to investigate the effects of NPWT on post-operative pain control and determine the feasibility of a larger trial.MethodTen consecutive patients undergoing oesophagectomy were prospectively enrolled to have a PREVENA Incision Management System placed over a closed thoracotomy wound. This dressing was changed at post-operative day 5 and removed after day 10. Post-operative morbidity was recorded and analgesia was prescribed by the Acute Pain Service who were blinded to the study aims. Analgesia requirements were recorded in oral morphine equivalents (OME) and compared to 30 patients that had previously undergone oesophagectomy via thoracotomy.ResultsOne patient was withdrawn from the study and there was no significant differences in patient demographics. The study group had less average daily analgesia requirements and reduced overall reported pain. Patients in the study group were less likely to develop pneumonia (44% and 57%) and less likely to require re-operation for complications of their surgery (0% and 10%).ConclusionThis pilot study shows reduced post-operative analgesia requirements and reduced morbidity when using NPWT over a closed thoracotomy wound, and affirms the feasibility of a future randomized control trial.
   Using negative pressure wound therapy dressing over a thoracotomy wound to improve post-operative pain control in patients undergoing oesophagectomy. Pilot study with results demonstrating a trend toward improved post-operative outcomes.image
C1 [Pavan, Fiona; Tan, Jed; Vu, Joseph; Martin, Sarah] Monash Hlth, Dept Gen Surg, Melbourne, Vic, Australia.
   [Gamage, Sankalpa] Monash Univ, Dept Med Nursing & Hlth Sci, Melbourne, Vic, Australia.
   [Cashin, Paul; Low, Liang; Martin, Sarah] Monash Hlth, Dept Upper GI & Hepatobiliary Surg, Melbourne, Vic, Australia.
   [Cashin, Paul] Jessie McPherson Private Hosp, Med Serv, Melbourne, Vic, Australia.
   [Cashin, Paul; Low, Liang; Martin, Sarah] Monash Univ, Dept Surg, Melbourne, Vic, Australia.
   [Pavan, Fiona] Monash Hlth, Dept Gen Surg, 246 Clayton Rd, Clayton, Vic 3168, Australia.
C3 Monash Health; Monash University; Monash Health; Jessie McPherson
   Private Hospital; Monash University; Monash Health
RP Pavan, F (通讯作者)，Monash Hlth, Dept Gen Surg, 246 Clayton Rd, Clayton, Vic 3168, Australia.
EM fiona.pavan@gmail.com
CR [Anonymous], OPIOID EQUIANALGESIA
   [Anonymous], OVERVIEW PERIPHERAL
   Australian Government- Human Services, MEDICARE STAT
   Chadi SA, 2014, DIS COLON RECTUM, V57, P999, DOI 10.1097/DCR.0000000000000161
   Ge DM, 2018, ADV SKIN WOUND CARE, V31, P421, DOI 10.1097/01.ASW.0000542530.71686.5c
   Gunatilake RP, 2017, AJP REP, V7, pE151, DOI 10.1055/s-0037-1603956
   Hughes R, 2005, BJA EDUC, V5, P56, DOI 10.1093/bjaceaccp/mki014
   National Bureau of Statistics of China, 2023, CDC GUID PREV SURG W, P9
   Savage N, 2020, AUSTRAL J PLAST SURG, V3, P30, DOI [10.34239/ajops.v3n1.165, 10.34239/ajops.v3n1.165, DOI 10.34239/AJOPS.V3N1.165]
   Soto RG, 2003, ANN THORAC SURG, V75, P1349, DOI 10.1016/S0003-4975(02)04647-7
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Yu LL, 2018, AM J OBSTET GYNECOL, V218, P200, DOI 10.1016/j.ajog.2017.09.017
NR 12
TC 1
Z9 1
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1445-1433
EI 1445-2197
J9 ANZ J SURG
JI ANZ J. Surg.
PD DEC
PY 2023
VL 93
IS 12
BP 2870
EP 2874
DI 10.1111/ans.18759
EA DEC 2023
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EJ3X7
UT WOS:001125476800001
PM 38093461
OA Bronze
DA 2026-07-24
ER

PT J
AU Su, F
   Cheng, L
   Tong, Q
AF Su, Feng
   Cheng, Liu
   Tong, Qiao
TI Effectiveness of tumescent solution combined with negative pressure
   wound therapy in traditional high ligation and stripping of the great
   saphenous vein
SO MEDICINE
LA English
DT Article
DE ecchymosis; high ligation and stripping of great saphenous vein; pain;
   tumescence solution
ID ENDOVENOUS LASER-ABLATION; FOAM SCLEROTHERAPY; VARICOSE-VEIN;
   MASTECTOMY; ANESTHESIA; SAFE
AB Traditional high ligation and stripping (THLS) is a routine operation for varicose veins. However, THLS is accompanied with postoperative subcutaneous ecchymosis and pain. In this current study, we aimed to explore the effect of tumescence solution (TS) combined with negative pressure wound therapy (NPWT) on the relief of subcutaneous ecchymosis and pain after THLS of great saphenous vein. A total of 180 patients receiving THLS were enrolled in group A, and 120 patients undergoing THLS and TS combined with NPWT were assigned into group B. The occurrences of subcutaneous ecchymosis and pain were recorded. Moreover, the total area of subcutaneous ecchymosis was estimated by the grid method. Visual analogue scale (VAS) score was used to assess the pain level of both groups. Preoperative characteristics were not significantly different between 2 groups. Postoperative ecchymosis occurred in 112 cases (62.2%) of group A and 41 cases (34.2%) of group B. The area of ecchymosis in group A (66.6 +/- 44.5) cm(2) was larger than that in group B (25.2 +/- 19.9) cm(2). The number of patients without obvious pain in group A (57, 31.7%) was significantly less than that in group B (77, 64.2%) after operation. In addition, VAS score in group A (3.1 +/- 2.6) was higher than that in group B (2.2 +/- 1.9). In conclusion, the application of TS combined with NPWT in THLS can not only alleviate subcutaneous ecchymosis and pain, but also prevent the occurrence of subcutaneous ecchymosis and pain after operation. Therefore, it is conducive to postoperative recovery and is suitable for clinical application.
C1 [Su, Feng] Nanjing Med Univ, Dept Vasc Surg, Xuzhou Sch Clin Med, Xuzhou, Jiangsu, Peoples R China.
   [Su, Feng] Xu Zhou Cent Hosp, Dept Vasc Surg, Xuzhou, Jiangsu, Peoples R China.
   [Cheng, Liu; Tong, Qiao] Nanjing Med Univ, Drum Tower Clin Med Coll, Dept Vasc Surg, 321 Zhongshan Rd, Nanjing 210008, Jiangsu, Peoples R China.
   [Cheng, Liu; Tong, Qiao] Nanjing Univ, Med Sch, Affiliated Drum Tower Hosp, Dept Vasc Surg, Nanjing, Peoples R China.
C3 Nanjing Medical University; Nanjing Medical University; Nanjing
   University
RP Tong, Q (通讯作者)，Nanjing Med Univ, Drum Tower Clin Med Coll, Dept Vasc Surg, 321 Zhongshan Rd, Nanjing 210008, Jiangsu, Peoples R China.
EM qiaotong31@163.com
CR Al Shakarchi J, 2018, J VASC SURG-VENOUS L, V6, P220, DOI 10.1016/j.jvsv.2017.08.013
   Badham GE, 2017, MINIM INVASIV THER, V26, P200, DOI 10.1080/13645706.2017.1282520
   Belramman A, 2019, ANGIOLOGY, V70, P388, DOI 10.1177/0003319718780049
   Brem MH, 2014, INT WOUND J, V11, P3, DOI 10.1111/iwj.12252
   Burleva E P, 2018, Angiol Sosud Khir, V24, P82
   Cavezzi A, 2017, EUR J VASC ENDOVASC, V54, P629, DOI 10.1016/j.ejvs.2017.08.004
   Epperla Narendranath, 2015, WMJ, V114, P61
   Epstein D, 2018, VALUE HEALTH, V21, P911, DOI 10.1016/j.jval.2018.01.012
   Gale SS, 2010, J VASC SURG, V52, P645, DOI 10.1016/j.jvs.2010.04.030
   George J, 2017, NEGATIVE PRESSURE WO, P1
   Guo B, 2016, ENDOVENOUS THERMAL A
   Gutowski KA, 2014, PLAST RECONSTR SURG, V134, p50S, DOI 10.1097/PRS.0000000000000678
   Hudson AJ, 2015, J VASC SURG-VENOUS L, V3, P48, DOI 10.1016/j.jvsv.2014.07.006
   Hwang JH, 2018, DERMATOL SURG, V44, P1287, DOI 10.1097/DSS.0000000000001543
   Kalteis M, 2008, J VASC SURG, V47, P822, DOI 10.1016/j.jvs.2007.10.060
   Khater A, 2017, BREAST CANCER-TARGET, V9, P237, DOI 10.2147/BCTT.S131398
   Kim J, 2017, J COSMET LASER THER, V19, P434, DOI 10.1080/14764172.2017.1342037
   Kim KY, 2017, ANN SURG TREAT RES, V93, P98, DOI 10.4174/astr.2017.93.2.98
   Klein JA, 2016, ANESTH ANALG, V122, P1350, DOI 10.1213/ANE.0000000000001119
   Luo Lihua, 2018, Zhong Nan Da Xue Xue Bao Yi Xue Ban, V43, P651, DOI 10.11817/j.issn.1672-7347.2018.06.012
   Nam D, 2018, J AM ACAD ORTHOP SUR, V26, P295, DOI 10.5435/JAAOS-D-17-00054
   Oliveira RD, 2018, SAO PAULO MED J, V136, P324, DOI 10.1590/1516-3180.2018.0003240418
   Pan Y, 2014, PHLEBOLOGY, V29, P109, DOI 10.1177/0268355512473911
   Proebstle T, 2017, VASA, V46, P159, DOI 10.1024/0301-1526/a000610
   Ran F, 2017, DERMATOL SURG, V43, P541, DOI 10.1097/DSS.0000000000001022
   Ren YH, 2017, INT J BURNS TRAUMA, V7, P12
   Scheltinga MR, 2007, WORLD J SURG, V31, P2236, DOI 10.1007/s00268-007-9211-3
   Stenger D, 2012, HAUTARZT, V63, P616, DOI 10.1007/s00105-012-2419-7
   Vargas CR, 2015, J SURG RES, V198, P525, DOI 10.1016/j.jss.2015.03.050
   Wallace T, 2017, PHLEBOLOGY, V32, P322, DOI 10.1177/0268355516653905
   Winterborn RJ, 2006, J CARDIOVASC SURG, V47, P19
   Zhao ZY, 2015, INT J CLIN EXP MED, V8, P7843
NR 32
TC 3
Z9 3
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD MAR
PY 2020
VL 99
IS 11
AR 19040
DI 10.1097/MD.0000000000019040
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA LC2ZQ
UT WOS:000525195500008
PM 32176031
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Brillantino, A
   Andreano, M
   Lanza, M
   D'Ambrosio, V
   Fusco, F
   Antropoli, M
   Lucia, A
   Zito, ES
   Forner, A
   Ambrosino, F
   Monte, G
   Cricri, AM
   Robustelli, U
   De Masi, A
   Calce, R
   Ciardiello, G
   Renzi, A
   Castriconi, M
AF Brillantino, Antonio
   Andreano, Mauro
   Lanza, Michele
   D'Ambrosio, Vito
   Fusco, Ferdinando
   Antropoli, Massimo
   Lucia, Antonella
   Zito, Enzo Saverio
   Forner, Anna
   Ambrosino, Francesco
   Monte, Giovanni
   Cricri, Antonio Maria
   Robustelli, Umberto
   De Masi, Alessandro
   Calce, Rosario
   Ciardiello, Giovanna
   Renzi, Adolfo
   Castriconi, Maurizio
TI Advantages of Damage Control Strategy With Abdominal Negative Pressure
   and Instillation in Patients With Diffuse Peritonitis From Perforated
   Diverticular Disease
SO SURGICAL INNOVATION
LA English
DT Article
DE diverticulitis; perforated diverticular disease; peritonitis; damage
   control surgery; open abdomen; Hartmann's procedure
ID INTERNATIONAL CONSENSUS DEFINITIONS; WOUND THERAPY; SEPSIS; GUIDELINES;
   MANAGEMENT; SURGERY
AB Purpose. To evaluate the results of Damage Control Strategy (DCS) in the treatment of generalized peritonitis from perforated diverticular disease in patients with preoperative severe systemic diseases. Methods. All the patients with diffuse peritonitis (Hinchey 3 and 4) and the American Society of Anesthesiologists (ASA) score >= 3 were included and underwent DCS consisting of a 2-step procedure. The first was peritoneal lavage, perforated colon-stapled resection, and temporary abdominal closure with negative pressure wound therapy combined with instillation. The second step, 48 hours later, included the possibility of restoring intestinal continuity basing on local and general patients' conditions. Results. Thirty patients (18 [60%] women and 12 [40%] men, median age 68.5 [range = 35-84] years) were included (18 [60%] ASA III, 11 [36.7%] ASA IV, and 1 [0.03%] ASA V). Seven patients (23.3%) showed sepsis and 1 (3.33%) septic shock. At second surgery, 24 patients (80%) received a colorectal anastomosis and 6 patients (20%) underwent a Hartmann's procedure. Median hospital stay was 18 days (range = 12-62). Postoperative morbidity rate was 23.3% (7/30) and included 1 anastomotic leak treated with Hartmann's procedure. Consequently, at discharge from hospital, 23 patients (76.6%) were free of stoma. Primary fascial closure was possible in all patients. Conclusions. DCS with temporary abdominal closure by negative pressure wound therapy combined with instillation in patients with diffuse peritonitis from complicated diverticulitis could represent a feasible surgical option both in hemodynamically stable and no stable patients, showing encouraging results including a low stoma rate and an acceptable morbidity rate.
C1 [Brillantino, Antonio; Andreano, Mauro; Lanza, Michele; D'Ambrosio, Vito; Fusco, Ferdinando; Antropoli, Massimo; Lucia, Antonella; Zito, Enzo Saverio; Forner, Anna; Ambrosino, Francesco; Monte, Giovanni; Cricri, Antonio Maria; Robustelli, Umberto; De Masi, Alessandro; Calce, Rosario; Ciardiello, Giovanna; Castriconi, Maurizio] A Cardarelli Hosp, Via A Cardarelli 9, I-80131 Naples, Italy.
   [Renzi, Adolfo] Villa delle Querce Hosp, Naples, Italy.
C3 Antonio Cardarelli Hospital
RP Brillantino, A (通讯作者)，A Cardarelli Hosp, Via A Cardarelli 9, I-80131 Naples, Italy.
EM antonio.brillantino@gmail.com
RI ; Renzi, Adolfo/AAL-7610-2020; Del Monte, Giovanni/LCD-2405-2024
OI Brillantino, Antonio/0000-0002-0198-8511; Renzi,
   Adolfo/0000-0002-6629-6057; 
CR Anghel EL, 2016, INT WOUND J, V13, P19, DOI 10.1111/iwj.12664
   Aronson Wendy L, 2003, AANA J, V71, P265
   Aydin HN, 2005, DIS COLON RECTUM, V48, P2117, DOI 10.1007/s10350-005-0168-8
   Brillantino A, 2018, EUR J TRAUMA EMERG S, V44, P265, DOI 10.1007/s00068-017-0805-7
   Brillantino A, 2016, EUR J TRAUMA EMERG S, V42, P593, DOI 10.1007/s00068-015-0575-z
   Brillantino Antonio, 2019, Bull Emerg Trauma, V7, P49, DOI [10.29252/beat-070107, 10.29252/beat-070107]
   Cirocchi R, 2014, MEDICINE, V93, DOI 10.1097/MD.0000000000000184
   Coccolini F, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0146-1
   DEMMEL N, 1994, LANGENBECK ARCH CHIR, V379, P347
   Galetin T, 2018, INT J COLORECTAL DIS, V33, P261, DOI 10.1007/s00384-017-2960-z
   Giannoudi M, 2016, EUR J TRAUMA EMERG S, V42, P273, DOI 10.1007/s00068-015-0628-3
   Hinchey E J, 1978, Adv Surg, V12, P85
   Hommes M, 2018, EUR J TRAUMA EMERG S, V44, P79, DOI 10.1007/s00068-017-0768-8
   Kafka-Ritsch R, 2012, J GASTROINTEST SURG, V16, P1915, DOI 10.1007/s11605-012-1977-4
   Kirkpatrick AW, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0183-4
   Krige JE, 2016, EUR J TRAUMA EMERG S, V42, P225, DOI 10.1007/s00068-015-0525-9
   Matthews Marc R, 2018, Eplasty, V18, pe12
   Perathoner A, 2010, INT J COLORECTAL DIS, V25, P767, DOI 10.1007/s00384-010-0887-8
   Rycerz AM, 2013, INT WOUND J, V10, P214, DOI 10.1111/j.1742-481X.2012.00968.x
   SANDERSON ER, 1980, ARCH SURG-CHICAGO, V115, P792, DOI 10.1001/archsurg.1980.01380060088026
   Sartelli M, 2016, WORLD J EMERG SURG, V11, DOI 10.1186/s13017-016-0095-0
   Seymour CW, 2016, JAMA-J AM MED ASSOC, V315, P762, DOI 10.1001/jama.2016.0288
   Shah SK, 2012, EUR J TRAUMA EMERG S, V38, P65, DOI 10.1007/s00068-011-0136-z
   Sibaja P, 2017, INT J SURG CASE REP, V30, P26, DOI 10.1016/j.ijscr.2016.11.024
   Singer M, 2016, JAMA-J AM MED ASSOC, V315, P801, DOI 10.1001/jama.2016.0287
   Sohn M, 2016, TECH COLOPROCTOL, V20, P577, DOI 10.1007/s10151-016-1506-7
   Sohn MA, 2018, INT J COLORECTAL DIS, V33, P871, DOI 10.1007/s00384-018-3025-7
   Sohn M, 2018, WORLD J SURG, V42, P3189, DOI 10.1007/s00268-018-4585-y
   Tahir S, 2018, MATERIALS, V11, DOI 10.3390/ma11050811
   Tilsed JVT, 2016, EUR J TRAUMA EMERG S, V42, P253, DOI 10.1007/s00068-016-0634-0
   Vermeulen J, 2009, COLORECTAL DIS, V11, P619, DOI 10.1111/j.1463-1318.2008.01667.x
NR 31
TC 18
Z9 19
U1 0
U2 5
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1553-3506
EI 1553-3514
J9 SURG INNOV
JI Surg. Innov.
PD DEC
PY 2019
VL 26
IS 6
BP 656
EP 661
DI 10.1177/1553350619857561
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA JL1RQ
UT WOS:000495310800002
PM 31221028
DA 2026-07-24
ER

PT J
AU Petrou, S
   Parker, B
   Masters, J
   Achten, J
   Bruce, J
   Lamb, SE
   Parsons, N
   Costa, ML
   Willett, K
   Griffin, D
   Jeffery, S
   Arrowsmith, J
   Datta, G
   Dennison, M
   Farrar, M
   Giannoudis, P
   Gray, A
   Henman, P
   Hull, P
   Khan, U
   Lewis, C
   Loveday, D
   Mangwani, J
   McAndrew, A
   McClelland, D
   McNicholas, M
   Noyes, D
   Ollivere, B
   Pallister, I
   Porter, K
   Ramachandran, M
   Rickard, R
   Rogers, B
   Sharma, H
   Tavakkolizadeh, M
   Young, J
AF Petrou, S.
   Parker, B.
   Masters, J.
   Achten, J.
   Bruce, J.
   Lamb, S. E.
   Parsons, N.
   Costa, M. L.
   Willett, Keith
   Griffin, Damian
   Jeffery, Steven
   Arrowsmith, Jill
   Datta, Gorav
   Dennison, Mick
   Farrar, Mark
   Giannoudis, Peter
   Gray, Andrew
   Henman, Philip
   Hull, Peter
   Khan, Umraz
   Lewis, Charlotte
   Loveday, David
   Mangwani, Jitendra
   McAndrew, Andrew
   McClelland, Damian
   McNicholas, Mike
   Noyes, David
   Ollivere, Ben
   Pallister, Ian
   Porter, Keith
   Ramachandran, Manoj
   Rickard, Rory
   Rogers, Benedict
   Sharma, Hemant
   Tavakkolizadeh, Mel
   Young, Jonathan
CA WOLLF Trial Collaborators
TI Cost-effectiveness of negative-pressure wound therapy in adults with
   severe open fractures of the lower limb: evidence from the WOLLF
   randomized controlled trial
SO BONE & JOINT JOURNAL
LA English
DT Article
ID HEALTH; INFECTION; DISABILITY; EUROQOL
AB Aims
   The aim of this study was to estimate the cost-effectiveness of negative-pressure wound therapy (NPWT) in comparison with standard wound management after initial surgical wound debridement in adults with severe open fractures of the lower limb.
   Patients and Methods
   An economic evaluation was conducted from the perspective of the United Kingdom NHS and Personal Social Services, based on evidence from the 460 participants in the Wound Management of Open Lower Limb Fractures (WOLLF) trial. Economic outcomes were collected prospectively over the 12-month follow-up period using trial case report forms and participant-completed questionnaires. Bivariate regression of costs (given in  pound, 2014 to 2015 prices) and quality-adjusted life-years (QALYs), with multiple imputation of missing data, was conducted to estimate the incremental cost per QALY gained associated with NPWT dressings. Sensitivity and subgroup analyses were undertaken to assess the impacts of uncertainty and heterogeneity, respectively, surrounding aspects of the economic evaluation.
   Results
   The base case analysis produced an incremental cost-effectiveness ratio of 267 pound 910 per QALY gained, reflecting higher costs on average (678; pound 95% confidence interval (CI) -1082 pound to 2438) pound and only marginally higher QALYS (0.002; 95% CI -0.054 to 0.059) in the NPWT group. The probability that NPWT is cost-effective in this patient population did not exceed 27% regardless of the value of the cost-effectiveness threshold. This result remained robust to several sensitivity and subgroup analyses.
   Conclusion
   This trial-based economic evaluation suggests that NPWT is unlikely to be a cost-effective strategy for improving outcomes in adult patients with severe open fractures of the lower limb.
C1 [Petrou, S.; Parker, B.] Univ Warwick, Warwick Med Sch, Warwick Clin Trials Unit, Hlth Econ, Gibbet Hill Campus, Coventry, W Midlands, England.
   [Bruce, J.] Univ Warwick, Warwick Med Sch, Warwick Clin Trials Unit, Clin Trials, Gibbet Hill Campus, Coventry, W Midlands, England.
   [Masters, J.] Univ Warwick, Coventry, W Midlands, England.
   [Achten, J.] Univ Warwick, Warwick Med Sch, Warwick Clin Trials Unit, Gibbet Hill Campus, Coventry, W Midlands, England.
   [Lamb, S. E.] Univ Warwick, Warwick Med Sch, Warwick Clin Trials Unit, Trauma & Rehabil, Gibbet Hill Campus, Coventry, W Midlands, England.
   [Parsons, N.] Univ Warwick, Warwick Med Sch, Stat & Epidemiol Unit, Gibbet Hill Campus, Coventry, W Midlands, England.
   [Costa, M. L.] Univ Warwick, Warwick Med Sch, Warwick Clin Trials Unit, Orthopaed Trauma, Gibbet Hill Campus, Coventry, W Midlands, England.
   [Petrou, S.] Univ Oxford, Nuffield Dept Primary Care Hlth Sci, Oxford, England.
   [Masters, J.; Lamb, S. E.; Costa, M. L.] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford Trauma, Oxford, England.
   [Costa, M. L.] Univ Hosp Coventry & Warwickshire NHS Trust, Clifford Bridge Rd, Coventry, W Midlands, England.
C3 University of Warwick; University of Warwick; University of Warwick;
   University of Warwick; University of Warwick; University of Warwick;
   University of Warwick; University of Oxford; University of Oxford;
   University of Warwick
RP Petrou, S (通讯作者)，Univ Warwick, Warwick Med Sch, Warwick Clin Trials Unit, Hlth Econ, Gibbet Hill Campus, Coventry, W Midlands, England.; Petrou, S (通讯作者)，Univ Oxford, Nuffield Dept Primary Care Hlth Sci, Oxford, England.
EM stavros.petrou@phc.ox.ac.uk
RI ; Parsons, Nick/AAA-8713-2019; Petrou, Stavros/ABD-8323-2021; Bruce,
   Julie/G-7588-2014; Achten, Juul/KUD-8515-2024; Masters,
   James/U-8764-2019; /A-5207-2013; Giannoudis, Peter/AAA-3617-2020;
   Arrowsmith, Jill/LTY-6777-2024
OI Costa, Matthew/0000-0003-3644-1388; Parsons, Nick/0000-0001-9975-888X;
   Petrou, Stavros/0000-0003-3121-6050; Bruce, Julie/0000-0002-8462-7999;
   Loveday, David/0000-0002-6383-2037; Griffin, Damian/0000-0003-0952-7848;
   Lamb, Sarah/0000-0003-4349-7195; Achten, Juul/0000-0002-8857-5743;
   Ollivere, Benjamin/0000-0002-1410-1756; Masters,
   James/0000-0001-9663-8858; Mangwani, Jitendra/0000-0002-3960-3023; 
FU UK National Institute for Health Research (NIHR) Health Technology
   Assessment (HTA) [10/57/20]; European Union (EU); Royal College of
   Surgeons England and Industry; NIHR; National Institute for Health
   Research [NF-SI-0616-10103, 10/57/20] Funding Source: researchfish; The
   Dunhill Medical Trust [DMT/RCS605] Funding Source: researchfish
FX S. Petrou, J. Achten, J. Bruce, S. E. Lamb, N. Parsons, and M. L. Costa
   report an institutional grant (paid to The University of Warwick) from
   the UK National Institute for Health Research (NIHR) Health Technology
   Assessment (HTA) Programme (project number 10/57/20), related to this
   study. M. L. Costa is also employed by the University of Oxford, which
   received institutional research fund grants from the NIHR, the European
   Union (EU), and the Royal College of Surgeons England and Industry.
CR Ali AM, 2015, ANN ROY COLL SURG, V97, P287, DOI 10.1308/003588415X14181254789367
   An Thomas J, 2016, J Surg Orthop Adv, V25, P49
   [Anonymous], 2013, Guide to the Methods of Technology Appraisal
   [Anonymous], 2015, RES AN NHS REF COSTS
   [Anonymous], 2016, Fractures (complex): assessment and management
   [Anonymous], 1998, MED DECIS MAKING
   Barber JA, 2000, STAT MED, V19, P3219, DOI 10.1002/1097-0258(20001215)19:23<3219::AID-SIM623>3.0.CO;2-P
   BLACK WC, 1990, MED DECIS MAKING, V10, P212, DOI 10.1177/0272989X9001000308
   Brazier JE, 2004, MED CARE, V42, P851, DOI 10.1097/01.mlr.0000135827.18610.0d
   Brooks R, 1996, HEALTH POLICY, V37, P53, DOI 10.1016/0168-8510(96)00822-6
   CHATTERJEE A, 2015, PRS GLOB OPEN, V3, DOI DOI 10.1097/GOX.0000000000000551
   Claxton K, 2015, HEALTH TECHNOL ASSES, V19, P1, DOI 10.3310/hta19140
   Costa ML, 2018, JAMA-J AM MED ASSOC, V319, P2280, DOI 10.1001/jama.2018.6452
   Court-Brown CM, 1998, INJURY, V29, P529, DOI 10.1016/S0020-1383(98)00125-9
   Curtis L., 2015, Unit Costs of Health and Social Care 2015
   Department of Health, 2015, NHS SUPPL CHAIN CAT
   Dolan P, 1997, MED CARE, V35, P1095, DOI 10.1097/00005650-199711000-00002
   Drummond MichaelF., 2002, Methods for the Economic Evaluation of Health Care Programmes
   Faria R, 2014, PHARMACOECONOMICS, V32, P1157, DOI 10.1007/s40273-014-0193-3
   Fenwick E, 2001, HEALTH ECON, V10, P779, DOI 10.1002/hec.635
   Gustilo RB, 2002, J BONE JOINT SURG AM, V84A, P682, DOI 10.2106/00004623-200204000-00029
   Holloway KL, 2017, ARCH OSTEOPOROS, V12, DOI 10.1007/s11657-017-0369-5
   Horan TC, 2008, AM J INFECT CONTROL, V36, P309, DOI 10.1016/j.ajic.2008.03.002
   Husereau D, 2013, VALUE HEALTH, V16, P231, DOI 10.1016/j.jval.2013.02.002
   Labler L, 2009, J TRAUMA, V66, P749, DOI 10.1097/TA.0b013e318171971a
   Louie KW, 2009, BMJ-BRIT MED J, V339, DOI 10.1136/bmj.b5092
   MacKenzie EJ, 2007, J BONE JOINT SURG AM, V89A, P1685, DOI 10.2106/JBJS.F.01350
   Manca A, 2005, HEALTH ECON, V14, P487, DOI 10.1002/hec.944
   Mody RM, 2009, J TRAUMA, V67, P758, DOI 10.1097/TA.0b013e3181af6aa6
   Nherera LM, 2017, WOUND REPAIR REGEN, V25, P474, DOI 10.1111/wrr.12530
   NHS Digital, 2014, PRESCR COSTS AN ENGL
   Office for National Statistics (ONS), 2015, ANN SURV HOURS EARN
   Parker B, 2018, BONE JOINT J, V100B, P1506, DOI 10.1302/0301-620X.100B11.BJJ-2018-0308.R1
   Petrou S, 2002, INT J TECHNOL ASSESS, V18, P705, DOI 10.1017/S026646230200051X
   Pollak AN, 2010, J BONE JOINT SURG AM, V92A, P7, DOI 10.2106/JBJS.H.00984
   SALEN BA, 1994, J CLIN EPIDEMIOL, V47, P1423, DOI 10.1016/0895-4356(94)90086-8
   Tissingh EK, 2017, INJURY, V48, P353, DOI 10.1016/j.injury.2016.12.017
   Tuffaha HW, 2015, J SURG RES, V195, P612, DOI 10.1016/j.jss.2015.02.008
   Ware JE, 1996, MED CARE, V34, P220, DOI 10.1097/00005650-199603000-00003
   White IR, 2011, STAT MED, V30, P377, DOI 10.1002/sim.4067
NR 40
TC 24
Z9 26
U1 0
U2 9
PU BRITISH EDITORIAL SOC BONE & JOINT SURGERY
PI LONDON
PA 22 BUCKINGHAM STREET, LONDON WC2N 6ET, ENGLAND
SN 2049-4394
J9 BONE JOINT J
JI Bone Joint J.
PD NOV
PY 2019
VL 101B
IS 11
BP 1392
EP 1401
DI 10.1302/0301-620X.101B11.BJJ-2018-1228.R2
PG 10
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Orthopedics; Surgery
GA JJ2MN
UT WOS:000493996400010
PM 31674241
DA 2026-07-24
ER

PT J
AU Abdelhakim, M
   Ogawa, R
AF Abdelhakim, Mohamed
   Ogawa, Rei
TI Emerging Therapies in Chronic Wound Healing: Advances in Stem Cell
   Therapy, Growth Factor Modulation, Mechanical Strategies and Adjuvant
   Interventions
SO DERMATOLOGY AND THERAPY
LA English
DT Review
DE Chronic wounds; Wound healing; Regenerative medicine; Mesenchymal stem
   cells; Adipose-derived stem cells; Growth factor therapy;
   Platelet-derived products; Negative pressure wound therapy; Shock wave
   therapy; Mechanobiology and tissue regeneration
ID AUTOLOGOUS KERATINOCYTES; SKIN; PATHWAYS; EFFICACY; ULCERS; FLAP
AB Chronic wounds pose a persistent clinical and economic burden, often failing to respond to standard care as a result of impaired angiogenesis, prolonged inflammation, and dysfunctional cellular activity. Emerging strategies in regenerative medicine offer new hope, particularly those focusing on stem cell therapy, growth factor modulation, and mechanical support. This narrative emphasizes the clinical applicability. We performed targeted searches of PubMed/MEDLINE and Embase using terms related to regenerative cell therapy, growth factor modulation, mechanical/physical strategies, adjuvant therapies, and platelet-derived products (PRP/PRF). We prioritized randomized/controlled studies, high-quality observational cohorts, meta-analyses, and consensus guidelines relevant to chronic wound healing, and we critically appraised heterogeneity and limitations. In particular, the latest innovations in chronic wound management, mesenchymal stem cells (MSCs), and adipose-derived stem cells (ASCs) have shown promise in promoting angiogenesis and modulating immune responses. Concurrently, the targeted delivery of cytokines such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and epidermal growth factor (EGF) is being optimized through advanced biomaterials to enhance healing microenvironments. Mechanical interventions, including negative pressure wound therapy (NPWT) and shock wave therapy, further support tissue repair and revascularization. Together, these approaches reflect a shift from symptomatic wound care to personalized, regenerative strategies. This review synthesizes preclinical and clinical data, explores translational challenges, and outlines future directions that integrate biology, bioengineering, and digital tools for optimized wound healing.
C1 [Abdelhakim, Mohamed; Ogawa, Rei] Nippon Med Sch, Dept Plast Reconstruct & Aesthet Surg, 1-1-5 Sendagi Bunkyo Ku, Tokyo 1138603, Japan.
C3 Nippon Medical School
RP Ogawa, R (通讯作者)，Nippon Med Sch, Dept Plast Reconstruct & Aesthet Surg, 1-1-5 Sendagi Bunkyo Ku, Tokyo 1138603, Japan.
EM r.ogawa@nms.ac.jp
CR Abdelhakim M, 2020, DERMATOLOGY THER, V10, P569, DOI 10.1007/s13555-020-00407-6
   Almeleh R, 2013, WOUNDS, V25, P18
   Ankrum J, 2010, TRENDS MOL MED, V16, P203, DOI 10.1016/j.molmed.2010.02.005
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Barolet AC, 2023, PHOTOBIOMOD PHOTOMED, V41, P147, DOI 10.1089/photob.2022.0127
   Barrientos S, 2008, WOUND REPAIR REGEN, V16, P585, DOI 10.1111/j.1524-475X.2008.00410.x
   Bayram Y, 2005, BRIT J PLAST SURG, V58, P988, DOI 10.1016/j.bjps.2005.04.031
   Bhutani S, 2012, INDIAN J PLAST SURG, V45, P316, DOI 10.4103/0970-0358.101309
   Brem H, 2007, J CLIN INVEST, V117, P1219, DOI 10.1172/JCI32169
   Cacchio A., 2009, PHYS THER, V89, P282
   Chan BCF, 2020, INT WOUND J, V17, P1791, DOI 10.1111/iwj.13468
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Cretu A, 2025, MEDICINA-LITHUANIA, V61, DOI 10.3390/medicina61010128
   Dash Biraja C., 2018, Bioengineering-Basel, V5, P23, DOI [10.3390/bioengineering5010023, 10.3390/bioengineering5010023]
   de Freitas LF, 2016, IEEE J SEL TOP QUANT, V22, DOI 10.1109/JSTQE.2016.2561201
   Duscher D, 2016, GERONTOLOGY, V62, P216, DOI 10.1159/000381877
   Esmaeilzadeh A, 2024, NANOMEDICINE-UK, V19, P915, DOI 10.2217/nnm-2023-0344
   Frese L, 2016, TRANSFUS MED HEMOTH, V43, P268, DOI 10.1159/000448180
   Gnanadhas DP, 2015, SCI REP-UK, V5, DOI 10.1038/srep17440
   Gorecka J, 2019, STEM CELL RES THER, V10, DOI 10.1186/s13287-019-1185-1
   Gupta GJ, 2017, ADV WOUND CARE, V6, P135, DOI 10.1089/wound.2016.0704
   Han SK, 2009, DERMATOL SURG, V35, P1342, DOI 10.1111/j.1524-4725.2009.01239.x
   Hu L, 2016, SCI REP-UK, V6, DOI 10.1038/srep32993
   Huang CY, 2013, TRENDS MOL MED, V19, P555, DOI 10.1016/j.molmed.2013.05.005
   Johnson J, 2023, J EXTRACELL VESICLES, V12, DOI 10.1002/jev2.12332
   Kaita Y, 2019, REGEN THER, V10, P92, DOI 10.1016/j.reth.2019.01.001
   Lee K, 2011, J R SOC INTERFACE, V8, P153, DOI 10.1098/rsif.2010.0223
   Leppiniemi J, 2017, ACS APPL MATER INTER, V9, P21959, DOI 10.1021/acsami.7b02756
   Mizuno H, 2017, PRINCIPLES OF GENDER-SPECIFIC MEDICINE: GENDER IN THE GENOMIC ERA, 3RD EDITION, P459, DOI 10.1016/B978-0-12-803506-1.00050-4
   Moustafa M, 2007, REGEN MED, V2, P887, DOI 10.2217/17460751.2.6.887
   Nagano H, 2021, SCI REP-UK, V11, DOI 10.1038/s41598-021-93642-6
   Nakagami H, 2005, ARTERIOSCL THROM VAS, V25, P2542, DOI 10.1161/01.ATV.0000190701.92007.6d
   Ogawa Rei, 2006, Curr Stem Cell Res Ther, V1, P13, DOI 10.2174/157488806775269043
   Ogawa R, 2012, WOUND REPAIR REGEN, V20, P149, DOI 10.1111/j.1524-475X.2012.00766.x
   Ogawa R, 2011, J NIPPON MED SCH, V78, P68, DOI 10.1272/jnms.78.68
   Orgill DP, 2013, INT WOUND J, V10, P15, DOI 10.1111/iwj.12170
   Oropallo A., 2024, STATPEARLS INTERNET
   Ross R, 2024, J INVEST DERMATOL, V144, P2730, DOI 10.1016/j.jid.2024.04.015
   Rustad KC, 2012, ADV WOUND CARE, V1, P147, DOI 10.1089/wound.2011.0314
   Schultz GS, 2003, WOUND REPAIR REGEN, V11, pS1, DOI 10.1046/j.1524-475X.11.s2.1.x
   Sen CK, 2021, ADV WOUND CARE, V10, P281, DOI 10.1089/wound.2021.0026
   Steed DL, 1996, J AM COLL SURGEONS, V183, P61
   Stone JA., 1997, DIABETES SPECTRUM, V10, P1
   Vanscheidt W, 2007, WOUND REPAIR REGEN, V15, P308, DOI 10.1111/j.1524-475X.2007.00231.x
   Vowden K., 2015, J WOUND CARE, V24, P267
   Werdin F, 2008, LANCET, V372, P1860, DOI 10.1016/S0140-6736(08)61793-6
   Wong VW, 2011, FASEB J, V25, P4498, DOI 10.1096/fj.10-178087
   Yang G, 2011, TOHOKU J EXP MED, V225, P285, DOI 10.1620/tjem.225.285
   Zhang KY, 2020, ACTA BIOMATER, V113, P289, DOI 10.1016/j.actbio.2020.07.011
   Zhang T, 2007, UNDERSEA HYPERBAR M, V34, P335
NR 50
TC 7
Z9 9
U1 3
U2 11
PU ADIS INT LTD
PI NORTHCOTE
PA 5 THE WAREHOUSE WAY, NORTHCOTE 0627, AUCKLAND, NEW ZEALAND
SN 2193-8210
EI 2190-9172
J9 DERMATOLOGY THER
JI Dermatol. Ther.
PD DEC
PY 2025
VL 15
IS 12
BP 3533
EP 3545
DI 10.1007/s13555-025-01564-2
EA OCT 2025
PG 13
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 9TK2N
UT WOS:001590904800001
PM 41075105
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Valenzuela, MM
   Averkamp, BJ
   Odum, SM
   Rowe, TM
   Fehring, TK
AF Valenzuela, Michael M.
   Averkamp, Benjamin J.
   Odum, Susan M.
   Rowe, Taylor M.
   Fehring, Thomas K.
TI Polymicrobial Colonization of Prosthetic Joint Infections Treated With
   Open Wound Management
SO JOURNAL OF ARTHROPLASTY
LA English
DT Article; Proceedings Paper
CT Meeting of the Hip-Society
CY OCT, 2021
CL Washington, DC
SP Hip Soc
DE prosthetic joint infection; open wound management; negative pressure
   wound therapy; polymicrobial; fungal
ID TOTAL KNEE ARTHROPLASTY; 2-STAGE EXCHANGE; HIP; THERAPY; DEBRIDEMENT;
   IRRIGATION; RETENTION; FAILURE
AB Background: Open wound management in prosthetic joint infection (PJI) patients has been used in problematic dehisced wounds hoping to stimulate granulation tissue and closure. However, infections that start as a monomicrobial PJI can become polymicrobial with resultant worse outcomes following open wound management. This study assessed the relationship between open wound management and the development of polymicrobial periprosthetic joint infections.
   Methods: We reviewed patients referred with a synovial cutaneous fistula. Patients with an open wound measuring less than 2 cm and less than two weeks of open wound management were excluded. Variables included original organisms cultured, type and length of open wound management, and organisms cultured at the time of revision infection surgery.
   Results: Of the 65 patients with a previous monomicrobial infection treated with open wound management, 22/65 (34%) progressed to a polymicrobial infection. Thirty (46%) wounds were packed open with gauze, 20 (31%) were managed with negative pressure wound therapy, and 15 (23%) had surface dressings only. Of the 22 patients who converted to a polymicrobial infection, only 10 (45%) were infection free at follow-up. In contrast, 30 of 43 patients (70%) whose infections remained monomicrobial were infection free at follow-up.
   Conclusion: Open wound management can lead to conversion from a monomicrobial to a polymicrobial PJI, a rate of 34% in this series. Open prosthetic wound management should be discontinued for a fear of converting a monomicrobial infection to a difficult to treat polymicrobial infection. Surgeons must be prudent in the use of open wound management. (C) 2022 Elsevier Inc. All rights reserved.
C1 [Valenzuela, Michael M.; Odum, Susan M.; Rowe, Taylor M.] OrthoCarolina Res Inst, Charlotte, NC USA.
   [Averkamp, Benjamin J.; Odum, Susan M.; Fehring, Thomas K.] Atrium Hlth Musculoskeletal Inst, Dept Orthopaed Surg, Charlotte, NC USA.
   [Fehring, Thomas K.] OrthoCarolina Hip & Knee Ctr, Charlotte, NC USA.
RP Fehring, TK (通讯作者)，OrthoCarolina, 2001 Vail Ave Suite 200A, Charlotte, NC 28207 USA.
OI Valenzuela, Michael/0000-0002-5092-4020
CR Ailaney N, 2021, J ARTHROPLASTY, V36, P2402, DOI 10.1016/j.arth.2020.11.039
   Bozic KJ, 2015, CLIN ORTHOP RELAT R, V473, P2131, DOI 10.1007/s11999-014-4078-8
   Brown TS, 2018, J ARTHROPLASTY, V33, P2605, DOI 10.1016/j.arth.2018.03.003
   Bryan AJ, 2017, J BONE JOINT SURG AM, V99, P2011, DOI [10.2106/JBJS.16.01103, 10.2106/jbjs.16.01103]
   Chen WH, 2021, J AM ACAD ORTHOP SUR, V29, P1024, DOI 10.5435/JAAOS-D-20-00939
   Fehring TK, 2013, CLIN ORTHOP RELAT R, V471, P250, DOI 10.1007/s11999-012-2373-9
   Flierl MA, 2017, J ARTHROPLASTY, V32, P2505, DOI 10.1016/j.arth.2017.03.051
   Fröschen FS, 2020, TECHNOL HEALTH CARE, V28, P721, DOI 10.3233/THC-192095
   Hansen E, 2013, CLIN ORTHOP RELAT R, V471, P3230, DOI 10.1007/s11999-013-2937-3
   Harris PA, 2009, J BIOMED INFORM, V42, P377, DOI 10.1016/j.jbi.2008.08.010
   Helito CP, 2020, BMC MUSCULOSKEL DIS, V21, DOI 10.1186/s12891-020-03510-z
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Kavolus JJ, 2019, J ARTHROPLASTY, V34, P710, DOI 10.1016/j.arth.2018.09.090
   Kelm J, 2009, INT J MED SCI, V6, P241
   Kirr R, 2006, ZBL CHIR, V131, pS79, DOI 10.1055/s-2005-921501
   Kuo FC, 2018, J ARTHROPLASTY, V33, P3555, DOI 10.1016/j.arth.2018.07.024
   Kurtz S, 2007, J BONE JOINT SURG AM, V89A, P780, DOI 10.2106/JBJS.F.00222
   Kurtz SM, 2012, J ARTHROPLASTY, V27, P61, DOI 10.1016/j.arth.2012.02.022
   Lehner B, 2006, ZBL CHIR, V131, pS160, DOI 10.1055/s-2006-921513
   Lora-Tamayo J, 2013, CLIN INFECT DIS, V56, P182, DOI 10.1093/cid/cis746
   Mahmud T, 2012, CLIN ORTHOP RELAT R, V470, P2730, DOI 10.1007/s11999-012-2358-8
   Marculescu CE, 2008, CLIN ORTHOP RELAT R, V466, P1397, DOI 10.1007/s11999-008-0230-7
   Moran E, 2007, J INFECTION, V55, P1, DOI 10.1016/j.jinf.2007.01.007
   Mortazavi SMJ, 2011, CLIN ORTHOP RELAT R, V469, P3049, DOI 10.1007/s11999-011-2030-8
   Newman JM, 2019, J ARTHROPLASTY, V34, P554, DOI 10.1016/j.arth.2018.11.017
   Pitta M, 2018, J ARTHROPLASTY, V33, P407, DOI 10.1016/j.arth.2017.09.041
   Pulido L, 2008, CLIN ORTHOP RELAT R, V466, P1710, DOI 10.1007/s11999-008-0209-4
   Sherrell JC, 2011, CLIN ORTHOP RELAT R, V469, P18, DOI 10.1007/s11999-010-1434-1
   Sousa Ricardo, 2018, J Bone Jt Infect, V3, P108, DOI [10.7150/jbji.24285, 10.7150/jbji.24285]
   Tande AJ, 2014, CLIN MICROBIOL REV, V27, P302, DOI 10.1128/CMR.00111-13
   Urish KL, 2018, J ARTHROPLASTY, V33, P1154, DOI 10.1016/j.arth.2017.11.029
   Wimmer MD, 2016, INT ORTHOP, V40, P1367, DOI 10.1007/s00264-015-2871-y
NR 32
TC 9
Z9 12
U1 0
U2 11
PU CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS
PI PHILADELPHIA
PA CURTIS CENTER, INDEPENDENCE SQUARE WEST, PHILADELPHIA, PA 19106-3399 USA
SN 0883-5403
EI 1532-8406
J9 J ARTHROPLASTY
JI J. Arthroplast.
PD JUL
PY 2022
VL 37
IS 7
SU S
BP S653
EP S656
DI 10.1016/j.arth.2022.03.016
EA MAY 2022
PG 4
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Orthopedics
GA 1X6FL
UT WOS:000807548000048
PM 35283231
OA Bronze
DA 2026-07-24
ER

PT J
AU Meyer, J
   Roos, E
   Abbassi, Z
   Buchs, NC
   Ris, F
   Toso, C
AF Meyer, Jeremy
   Roos, Elin
   Abbassi, Ziad
   Buchs, Nicolas C.
   Ris, Frederic
   Toso, Christian
TI Prophylactic Negative-pressure Wound Therapy Prevents Surgical Site
   Infection in Abdominal Surgery: An Updated Systematic Review and
   Meta-analysis of Randomized Controlled Trials and Observational Studies
SO CLINICAL INFECTIOUS DISEASES
LA English
DT Article
DE PREVENA; PICO; NPWT; SSI; surgical site infection; pNPWT
ID LAPAROTOMY INCISIONS; OUTCOMES; IMPACT; COSTS
AB Background. Prevention of surgical site infection (SSI) is a public health challenge. Our objective was to determine if prophylactic negative-pressure wound therapy (pNPWT) allows preventing SSI after laparotomy.
   Methods. Medline, Embase, and Web of Science were searched on 6 October 2019 for original studies reporting the incidences of SSI in patients undergoing open abdominal surgery with and without pNPWT. Risk differences (RDs) between control and pNPWT patients and risk ratios (RRs) for SSI were obtained using random-effects models.
   Results. Twenty-one studies (2930 patients, 5 randomized controlled trials [RCTs], 16 observational studies) were retained for the analysis. Pooled RD between patients with and without pNPWT was -12% (95% confidence interval [CI], -17% to -8%; I-2 = 57%; P < .00001) in favor of pNPWT. That risk difference was -12% (95% CI, -22% to -1%; I-2 = 69%; P = .03) when pooling only RCTs (792 patients). pNPWT was protective against the incidence of SSI with a RR of 0.53 (95% CI,.40-.71; I-2 = 56%; P < .0001). The effect on pNPWT was more pronounced in studies with an incidence of SSI >= 20% in the control arm. The preventive effect of pNPWT on SSI remained after correction for potential publication bias. However, when pooling only high-quality observational studies (642 patients) or RCTs (527 patients), significance was lost.
   Conclusions. Existing studies suggest that pNPWT on closed wounds is protective against the occurrence of SSI in abdominal surgery, but these findings need to be confirmed by more high-quality evidence, preferentially in subgroups of patients with an incidence of SSI >= 20% in the control arm.
C1 [Meyer, Jeremy; Abbassi, Ziad; Buchs, Nicolas C.; Ris, Frederic; Toso, Christian] Univ Hosp Geneva, Div Digest Surg, Rue Gabrielle Perret Gentil 4, CH-1211 Geneva 14, Switzerland.
   [Meyer, Jeremy; Abbassi, Ziad; Buchs, Nicolas C.; Ris, Frederic; Toso, Christian] Univ Geneva, Unit Surg Res, Geneva, Switzerland.
   [Roos, Elin] Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden.
C3 University of Geneva; University of Geneva; Karolinska Institutet
RP Meyer, J (通讯作者)，Univ Hosp Geneva, Div Digest Surg, Rue Gabrielle Perret Gentil 4, CH-1211 Geneva 14, Switzerland.
EM jeremy.meyer@hcuge.ch
RI Abbassi, Ziad/HZL-6239-2023; Meyer, Jeremy/AAP-3367-2020; Toso,
   Christian/E-7785-2018; Ris, Frederic/H-7030-2019
OI Abbassi, Ziad/0000-0002-4130-5084; Meyer, Jeremy/0000-0003-3381-9146;
   Toso, Christian/0000-0003-1652-4522; Ris, Frederic/0000-0001-7421-6101
CR Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe276, DOI [10.1016/s1473-3099(16)30402-9, 10.1016/s1473-3099(16)30398-x, 10.1016/S1473-3099(16)30398-X]
   [Anonymous], 2020, ANN SURG 2020, DOI [10.1097/SLA.0000000000003841, DOI 10.1097/SLA.0000000000003841]
   Badia JM, 2017, J HOSP INFECT, V96, P1, DOI 10.1016/j.jhin.2017.03.004
   Blackham AU, 2013, AM J SURG, V205, P647, DOI 10.1016/j.amjsurg.2012.06.007
   Bonds AM, 2013, DIS COLON RECTUM, V56, P1403, DOI 10.1097/DCR.0b013e3182a39959
   Burkhart RA, 2017, HPB, V19, P825, DOI 10.1016/j.hpb.2017.05.004
   Cochrane Collaboration,, RAND EFF METH
   Cochrane Collaboration, ABOUT US
   Condé-Green A, 2013, ANN PLAS SURG, V71, P394, DOI 10.1097/SAP.0b013e31824c9073
   Covidence, ABOUT US
   Curran T, 2019, COLORECTAL DIS, V21, P110, DOI 10.1111/codi.14350
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   de Vries FEE, 2017, HERNIA, V21, P583, DOI 10.1007/s10029-017-1620-0
   Diaconu SC, 2020, HERNIA, V24, P49, DOI 10.1007/s10029-018-1865-2
   Duval S, 2000, BIOMETRICS, V56, P455, DOI 10.1111/j.0006-341X.2000.00455.x
   Gassman A, 2015, HERNIA, V19, P273, DOI 10.1007/s10029-014-1312-y
   GlobalSurg Collaborative, 2018, Lancet Infect Dis, V18, P516, DOI [10.1016/S1473-3099(18)30101-4, 10.1016/s1473-3099(18)30101-4]
   Gupta R, 2017, AM SURGEON, V83, P1166
   Higgins JPT, 2011, BMJ-BRIT MED J, V343, DOI 10.1136/bmj.d5928
   HORAN TC, 1992, AM J INFECT CONTROL, V20, P271, DOI 10.1016/S0196-6553(05)80201-9
   Javed AA, 2019, ANN SURG, V269, P1034, DOI 10.1097/SLA.0000000000003056
   Jenks PJ, 2014, J HOSP INFECT, V86, P24, DOI 10.1016/j.jhin.2013.09.012
   Kuper TM, 2020, ANN SURG, V271, P67, DOI 10.1097/SLA.0000000000003435
   Li PY, 2017, SCAND J SURG, V106, P189, DOI 10.1177/1457496916668681
   Mahmoud NN, 2009, SURG INFECT, V10, P539, DOI 10.1089/sur.2009.006
   Mehdorn M, 2020, ACTA CHIR BELG, V120, P250, DOI 10.1080/00015458.2019.1599180
   Moher D, 2009, J CLIN EPIDEMIOL, V62, P1006, DOI 10.1016/j.jclinepi.2009.06.005
   Murphy PB, 2019, ANN SURG, V270, P38, DOI 10.1097/SLA.0000000000003111
   National Institute for Health and Care Excellence,, 2019, PICO NEG PRESS WOUND
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Pauli EM, 2013, SURG INFECT, V14, P270, DOI 10.1089/sur.2012.059
   Pellino G, 2014, INT J SURG, V12, pS64, DOI 10.1016/j.ijsu.2014.08.378
   Roos E, COMMENT META A UNPUB
   Sahebally SM, 2018, JAMA SURG, V153, DOI 10.1001/jamasurg.2018.3467
   Sawyer RG, 2018, LANCET INFECT DIS, V18, P477, DOI 10.1016/S1473-3099(18)30118-X
   Schurtz E, 2018, AM J SURG, V215, P113, DOI 10.1016/j.amjsurg.2017.08.009
   Selvaggi Francesco, 2014, Surg Technol Int, V24, P83
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Urban Joshua A, 2006, Surg Infect (Larchmt), V7 Suppl 1, pS19, DOI 10.1089/sur.2006.7.s1-19
   Vargo D, 2012, AM J SURG, V204, P1021, DOI 10.1016/j.amjsurg.2012.10.004
   Webster J, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub4
   Wells CI, 2019, WORLD J SURG, V43, P2779, DOI 10.1007/s00268-019-05116-6
   Wells G., 2014, The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses, DOI DOI 10.1007/S10654-010-9491-Z
   Zaidi A, 2017, COLORECTAL DIS, V19, P283, DOI 10.1111/codi.13458
   Zimlichman E, 2013, JAMA INTERN MED, V173, P2039, DOI 10.1001/jamainternmed.2013.9763
   Zwanenburg PR, 2020, ANN SURG, V272, P81, DOI 10.1097/SLA.0000000000003644
NR 46
TC 26
Z9 28
U1 0
U2 5
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1058-4838
EI 1537-6591
J9 CLIN INFECT DIS
JI Clin. Infect. Dis.
PD DEC 1
PY 2021
VL 73
IS 11
BP E3804
EP E3813
DI 10.1093/cid/ciaa1203
PG 10
WC Immunology; Infectious Diseases; Microbiology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Immunology; Infectious Diseases; Microbiology
GA XW0GU
UT WOS:000735309500029
PM 32818259
OA Green Accepted, Bronze
DA 2026-07-24
ER

PT J
AU Guerreschi, P
   Casanova, D
   Maunoury, F
   Sinna, R
   Revol, M
AF Guerreschi, P.
   Casanova, D.
   Maunoury, F.
   Sinna, R.
   Revol, M.
TI ALGINATE versus negative-pressure therapy: Comparison of the clinical
   effectiveness, tolerance and costs in management of patients after
   surgical excision. Multicenter, randomized non-inferiority clinical
   trial on 113 patients
SO ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE
LA French
DT Article
DE Calcium alginate dressing; Negative Pressure Wound Therapy; Skin
   excision; Cost of patient care
AB Introduction. - Pure calcium alginate dressing (ALGINATE) and Negative Pressure Wound Therapy (NPWT) are frequently used for the preparation of skin excisions for a split thickness skin graft take. The trial compared the healing efficacy, safety and cost of patient care for these two treatments.
   Patients and methods. - This randomized, non-inferiority trial enrolled 113 patients who underwent skin excision (> 30 cm(2)) and received ALGINATE or NPWT. The primary outcome was the time to obtain optimal granulation tissue for a split thickness skin graft take. Secondary outcomes were the occurrence of adverse events (AEs) and the impact of the patient care cost on the Social Security budget.
   Results. - The mean time to optimal granulation was similar between ALGINATE and NPWT: approximately 20 days. No AE was reported with ALGINATE while 24 % of patients treated with NPWT presented an AE. Following hospitalization, 94 % of ALGINATE patients were cared for at home by a private nurse, while 90 % of NPWT patients were followed up in aftercare and rehabilitation facilities or home hospitalization. Therefore, the cost of treatment per patient for the French Social Security was 498 (sic) with ALGINATE and 2104 (sic) with NPWT.
   Conclusion. - This trial has demonstrated that ALGINATE has a similar healing efficacy to that of NPWT, and that it is markedly better with regard to patient safety and cost savings. ALGINATE should therefore be preferred to NPWT in this indication. (C) 2020 Elsevier Masson SAS. All rights reserved.
C1 [Guerreschi, P.] CHRU Lille, Dept Chirurg Plast Esthet & Reconstructrice, 2 Ave Oscar Lambret, F-59000 Lille, France.
   [Casanova, D.] Hop Conception, Dept Chirurg Plast & Reconstructrice, 147 Blvd Baille, F-13005 Marseille, France.
   [Maunoury, F.] STATESIA, 19 Rue Gougeard, F-72530 Yvre Leveque, France.
   [Sinna, R.] CHU Amiens Picardie, Dept Chirurg Plast Esthet & Reconstructrice, 1 Rue Prof Christian Cabrol, F-80054 Amiens, France.
   [Revol, M.] Univ Paris, UFR Villemin, F-75010 Paris, France.
C3 Universite de Lille; CHU Lille; Aix-Marseille Universite; Assistance
   Publique-Hopitaux de Marseille; Universite de Picardie Jules Verne
   (UPJV); CHU Amiens; Universite Paris Cite
RP Revol, M (通讯作者)，Univ Paris, UFR Villemin, F-75010 Paris, France.
EM mrevol05@gmail.com
RI P, Guerreschi/H-4757-2015
CR Ameli fr, 2020, NOMENCLATURE GEN ACT
   Ameli fr, 2020, LISTE PRODUITS PREST
   Andre J., 1997, Revue de l'adphso, V22, P69
   [Anonymous], 2016, PROFESSIONNELS SEDA
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Beral D, 2009, BMJ-BRIT MED J, V338, DOI 10.1136/bmj.b2269
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   Casanova D, 2020, PLAST RECONSTR SURG
   Dumville JC, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011278.pub2
   Haute Autorite de sante, 2012, ANN DERMATOL VENER, V139, P753
   Haute Autorite de sante, 2020, CHOIX METHODOLOGIQUE, P1
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Lalau JD, 2002, DIABETES METAB, V28, P223
   Le Franc B, 2010, ANN CHIR PLAST ESTH, V55, P195, DOI 10.1016/j.anplas.2009.04.001
   Li ZH, 2014, WOUND REPAIR REGEN, V22, P457, DOI 10.1111/wrr.12190
   Mattox EA, 2017, CRIT CARE NURSE, V37, P67, DOI 10.4037/ccn2017308
   Mazoch M, 2015, J WOUND CARE, V24, pS18, DOI 10.12968/jowc.2015.24.Sup6.S18
   Mody GN, 2008, OSTOMY WOUND MANAG, V54, P36
   Monsen C, 2015, J WOUND CARE, V24, P252, DOI 10.12968/jowc.2015.24.6.252
   Monsen C, 2014, J VASC SURG, V59, P145, DOI 10.1016/j.jvs.2013.06.073
   Moues C M, 2005, J Wound Care, V14, P224
   Penn JG, 1996, PATIENT CARE PLASTIC, P552
   Petrou S, 2019, BONE JOINT J, V101B, P1392, DOI 10.1302/0301-620X.101B11.BJJ-2018-1228.R2
   Piaggio G, 2012, JAMA-J AM MED ASSOC, V308, P2594, DOI 10.1001/jama.2012.87802
   Qin YM, 2008, POLYM INT, V57, P171, DOI 10.1002/pi.2296
   Rencuzogullari A, 2015, INT WOUND J, V12, P739, DOI 10.1111/iwj.12200
   Revol M, 2010, ENCY MED CHIR, V45, P10
   Revol M, 2010, GREFFES CUTANEES, P1
   Saaiq M, 2010, JCPSP-J COLL PHYSICI, V20, P675, DOI 04.2010/JCPSP.675679
   sante Udedtedmdie, 2010, UTILISATION THERAPIE
   Sayag J., 1996, J Wound Care, V5, P357, DOI DOI 10.12968/JOWC.1996.5.8.357
   Schmidt R J., 1986, Pharmaceutical Journal, V236, P36
   Thomas S, 2000, J Wound Care, V9, P56
   Thomas S, 2000, J Wound Care, V9, P163
   Wagstaff MJD, 2014, WOUND REPAIR REGEN, V22, P205, DOI 10.1111/wrr.12146
NR 35
TC 1
Z9 1
U1 0
U2 4
PU ELSEVIER
PI BRIDGEWATER
PA 685 ROUTE 202-206, BRIDGEWATER, NJ 08807 USA
SN 0294-1260
EI 1768-319X
J9 ANN CHIR PLAST ESTH
JI Ann. Chir. Plast. Esthet.
PD FEB
PY 2021
VL 66
IS 1
BP 3
EP 9
DI 10.1016/j.anplas.2020.11.001
EA FEB 2021
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA QD1HP
UT WOS:000615278900003
PM 33279277
DA 2026-07-24
ER

PT J
AU Zhang, F
   Lv, KY
   Qiu, XC
   Luo, PF
   Zheng, XF
   Zhu, SH
   Xia, ZF
AF Zhang, Fang
   Lv, Kai-Yang
   Qiu, Xiao-Chen
   Luo, Peng-Fei
   Zheng, Xing-Feng
   Zhu, Shi-Hui
   Xia, Zhao-Fan
TI Using negative pressure wound therapy on microskin autograft wounds
SO JOURNAL OF SURGICAL RESEARCH
LA English
DT Article
DE NPWT; Skin defect; Microskin graft; Skin grafting; Wound repair
ID OF-THE-LITERATURE; SKIN-GRAFTS; CLOSURE; TRIAL; MANAGEMENT; DEVICE; LEG
AB Background: Microskin autografts with conventional wrap and compression are used extensively in the treatment of skin and tissue defects. This comparative study aimed at investigation of the clinical application of negative pressure wound therapy (NPWT) in combination with microskin autografts for repair of acute and chronic wounds.
   Methods: A prospective case-control study was performed from December 1, 2010-December 31, 2013 in Changhai Hospital, Shanghai. We compared a study group of patients received microskin autografting covered by NPWT with that of a control group of patients received microskin autografting covered by a conventional gauze.
   Results: A total of 81 patients were in this study, 27 patients were allocated to the study group and 54 patients to the control group. The study group exhibited significant low infection rate and pain score during removal of inner layer at first dressing change after skin grafting compared with those of the control group (P < 0.05). The time interval between skin grafting and first postoperative change was longer in the study group than that in the control group (P < 0.01), the study group showed a significant shorter 95% wound healing time (P < 0.05), and survival rate of microskin autografts in the study group was higher than that in the control group (P < 0.05).
   Conclusions: NPWT is beneficial for wound closure after microskin autografts, which prolongs the interval between skin transplantation and first postoperative dressing change, reduces pain during removal of inner layer dressing, increases skin graft survival rate, and shortens wound healing time. Therefore, NPWT can be recommended for repair of acute and chronic wounds with microskin autografts. (C) 2015 Elsevier Inc. All rights reserved.
C1 [Zhang, Fang; Lv, Kai-Yang; Luo, Peng-Fei; Zheng, Xing-Feng; Zhu, Shi-Hui; Xia, Zhao-Fan] Second Mil Med Univ, Affiliated Changhai Hosp, Dept Burn Surg, Shanghai 200433, Peoples R China.
   [Zhang, Fang] 73901 Troop PLA, Shanghai, Peoples R China.
   [Qiu, Xiao-Chen] 309th Hosp PLA, Dept Burns & Plast Surg, Beijing, Peoples R China.
C3 Naval Medical University
RP Zhu, SH (通讯作者)，Second Mil Med Univ, Affiliated Changhai Hosp, Dept Burn Surg, Shanghai 200433, Peoples R China.
EM doctorzhushihui@163.com; xiazhaofan@163.com
RI Zheng, Xingfeng/C-2982-2011
FU National Natural Science Foundation of China [81000308, 81120108015];
   Science and Technology Commission of Shanghai Municipality
   [12QA1404400]; 1255 Foundation of Changhai Hospital [CH125510207,
   CH125510208, CH125510212]
FX This work was financially supported by the key project of the National
   Natural Science Foundation of China (No. 81120108015), the National
   Natural Science Foundation of China (No. 81000308), the Science and
   Technology Commission of Shanghai Municipality (No. 12QA1404400) and the
   1255 Foundation of Changhai Hospital (No. CH125510207, CH125510208,
   CH125510212). The authors acknowledge Professor Sheng-De Ge for formal
   English revision of the article.
CR Atiyeh BS, 2005, BURNS, V31, P944, DOI 10.1016/j.burns.2005.08.023
   Auxenfans C, 2014, BURNS
   Beno M, 2010, Rozhl Chir, V89, P508
   Caruso DM, 2006, J BURN CARE RES, V27, P298, DOI 10.1097/01.BCR.0000216741.21433.66
   Chen Jiong, 2009, Zhonghua Yi Xue Za Zhi, V89, P105
   Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
   Demirtas Y, 2010, BURNS, V36, P999, DOI 10.1016/j.burns.2009.05.017
   Flack S, 2008, J Wound Care, V17, P71
   Glass GE, 2014, BR J SURG
   Guffanti A, 2014, J WOUND OSTOMY CONT, V41, P233, DOI 10.1097/WON.0000000000000021
   Gupta S, 2012, INT WOUND J, V9, P40, DOI 10.1111/j.1742-481X.2012.01019.x
   Hsu CC, 2013, J DERMATOL SCI, V70, P196, DOI 10.1016/j.jdermsci.2013.03.007
   Kim Roderick Y, 2014, Ann Maxillofac Surg, V4, P4, DOI 10.4103/2231-0746.133064
   Kmetec A, 2013, RADIOL ONCOL, V47, P289, DOI 10.2478/raon-2013-0041
   Li RG, 2013, MED SCI MONITOR, V19, P510, DOI 10.12659/MSM.883963
   Liu DH, 2014, CELL BIOCHEM BIOPHYS, V70, P539, DOI 10.1007/s12013-014-9953-0
   Liu L, 2012, INT ORTHOP, V36, P1441, DOI 10.1007/s00264-011-1404-6
   Mendonca Derick A, 2006, Int Wound J, V3, P261, DOI 10.1111/j.1742-481X.2006.00266.x
   Mouës CM, 2007, J PLAST RECONSTR AES, V60, P672, DOI 10.1016/j.bjps.2006.01.041
   Myles PS, 1999, ANESTH ANALG, V89, P1517, DOI 10.1097/00000539-199912000-00038
   Payne Caroline, 2014, Eplasty, V14, pe20
   Petkar KS, 2011, BURNS, V37, P925, DOI 10.1016/j.burns.2011.05.013
   Qu JF, 2013, EXP THER MED, V5, P1375, DOI 10.3892/etm.2013.999
   Ramanujam CL, 2013, DIABET FOOT ANKLE, V23, P4
   Richard JL, 2011, WORLD J DIABETES, V2, P24, DOI 10.4239/wjd.v2.i2.24
   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Stetter Christoph, 2006, J Dtsch Dermatol Ges, V4, P739, DOI 10.1111/j.1610-0387.2006.06034.x
   Tautenhahn J, 2004, CHIRURG, V75, P492, DOI 10.1007/s00104-004-0844-6
   Upton D, 2012, J WOUND CARE, V21, P53, DOI 10.12968/jowc.2012.21.2.53
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Vig S, 2011, J TISSUE VIABILITY, V20, pS1, DOI 10.1016/j.jtv.2011.07.002
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Wild T, 2008, INT WOUND J, V5, P641, DOI 10.1111/j.1742-481X.2007.00407.x
   Yang SL, 2014, WOUND REPAIR REGEN, V22, P548, DOI 10.1111/wrr.12195
NR 35
TC 16
Z9 20
U1 0
U2 19
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0022-4804
EI 1095-8673
J9 J SURG RES
JI J. Surg. Res.
PD MAY 1
PY 2015
VL 195
IS 1
BP 344
EP 350
DI 10.1016/j.jss.2014.12.025
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CE9CA
UT WOS:000352139900044
PM 25586332
DA 2026-07-24
ER

PT J
AU Salgarello, M
   Domar, NL
   Visconti, G
   Scardina, L
   D'Archi, S
   Di Leone, A
   Franceschini, G
   Adesi, LB
AF Salgarello, Marzia
   Lazzeri Domar, Niccolo
   Visconti, Giuseppe
   Scardina, Lorenzo
   D'archi, Sabatino
   Di Leone, Alba
   Franceschini, Gianluca
   Barone Adesi, Liliana
TI Can the Use of Closed Incision Negative Pressure Wound Therapy in
   Immediate Prepectoral Breast Reconstruction With Polyurethane-Coated
   Implants Reduce the Rate of Early Complications?: A Comparative Study
SO AESTHETIC SURGERY JOURNAL
LA English
DT Article; Early Access
ID SURGICAL SITE INFECTION; MASTECTOMY; OUTCOMES; SURGERY; RISK
AB Background: Immediate prepectoral breast reconstruction with polyurethane-coated implants provides esthetic and functional benefits compared with subpectoral techniques, but early postoperative complications remain a concern. Closed incision negative pressure wound therapy (ciNPWT) has demonstrated benefits in other surgical fields, though evidence in breast reconstruction is limited. Objectives: To evaluate whether ciNPWT reduces early postoperative complications after immediate prepectoral reconstruction with polyurethane-coated implants, particularly in high-risk patients. Methods: We retrospectively analyzed 620 patients undergoing unilateral or bilateral conservative mastectomy with immediate prepectoral reconstruction using polyurethane-coated implants between May 2021 and February 2024. Patients were divided into 2 cohorts: 257 treated with ciNPWT and 363 with conventional dressings. Subgroup analyses considered mastectomy flap thickness (0.5-0.6 cm, 0.7-0.9 cm, >= 1.0 cm) and specimen weight (<500 g vs >= 500 g). Early complications (<= 30 days) were classified as major (requiring reoperation or hospitalization) or minor. Results: ciNPWT significantly reduced major complications compared with controls: wound dehiscence (1.17% vs 6.61%), flap ischemia (0% vs 2.2%), major infection (0.39% vs 2.48%), and implant extrusion (0.39% vs 2.2%). Minor complications, including periprosthetic seromas, were also reduced (4.28% vs 5.79%). The protective effect was most evident in patients with thin mastectomy flaps (0.5-0.9 cm) and specimen weight >= 500 g. Correlation between intraoperative flap thickness and preoperative Rancati score confirmed benefits in high-risk patients (Rancati type 1). Conclusions: ciNPWT reduces early complications in immediate prepectoral reconstruction, with greatest benefit in high-risk patients. Integration into reconstructive protocols may enhance safety and broaden indications. Prospective randomized trials are warranted.
C1 [Salgarello, Marzia; Visconti, Giuseppe; Barone Adesi, Liliana] Univ Cattolica Sacro Cuore, Fdn Policlin Univ Agostino Gemelli IRCCS, UOSD Chirurg Plast, Dipartimento Salute Donna Bambino & Sanita Publ, Rome, Italy.
   [Lazzeri Domar, Niccolo] Univ Cattolica Sacro Cuore, Residency Program in Plast Surg, Rome, Italy.
   [D'archi, Sabatino; Di Leone, Alba; Franceschini, Gianluca] Univ Cattolica Sacro Cuore, Bambino & San Pubbl Fdn Policlin Univ Agostino Gem, Dipartimento Salute Donna, UOC Chirurg Senolog, Rome, Italy.
C3 Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli;
   Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli;
   Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli
RP Domar, NL (通讯作者)，Largo Agostino Gemelli 8, I-00168 Rome, Italy.
EM n.lazzeridomar@gmail.com
RI ; Salgarello, Marzia/GYJ-2938-2022; Visconti, Giuseppe/N-9292-2019;
   Scardina, Lorenzo/ABC-9506-2022; Barone-Adesi, liliana/GXV-8243-2022;
   Franceschini, Gianluca/C-5491-2016; Di Leone, Alba/AAD-2050-2022;
   D'Archi, Sabatino/M-3451-2017
OI Lazzeri Domar, Niccolò/0009-0006-3042-7082; Visconti,
   Giuseppe/0000-0002-0041-5420; Scardina, Lorenzo/0000-0002-5828-2851;
   Franceschini, Gianluca/0000-0002-2950-3395; Di Leone,
   Alba/0000-0002-8219-5336; 
CR ABE O, 1995, NEW ENGL J MED, V333, P1444
   Alderman AK, 2002, PLAST RECONSTR SURG, V109, P2265, DOI 10.1097/00006534-200206000-00015
   Annacontini L., 2016, Ann Ital Chir, V5, P1
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Barone Adesi Liliana, 2025, J Pers Med, V15, DOI [10.3390/jpm15030114, 10.3390/jpm15030114]
   Beecher SM, 2016, BRIT J SURG, V103, P391, DOI 10.1002/bjs.10068
   Cagney D, 2020, WORLD J SURG, V44, P1526, DOI 10.1007/s00268-019-05335-x
   Catanuto G, 2024, AESTHET SURG J, V44, P491, DOI 10.1093/asj/sjad301
   Chattha A, 2017, J SURG ONCOL, V116, P811, DOI 10.1002/jso.24753
   Chun YS, 2010, PLAST RECONSTR SURG, V125, P429, DOI 10.1097/PRS.0b013e3181c82d90
   de Blacam C, 2012, ANN SURG, V255, P551, DOI 10.1097/SLA.0b013e318246c294
   Duxbury PJ, 2016, J PLAST RECONSTR AES, V69, P452, DOI 10.1016/j.bjps.2016.01.013
   Fang SY, 2013, BREAST CANCER RES TR, V137, P13, DOI 10.1007/s10549-012-2349-1
   Frame J, 2015, AESTHET PLAST SURG, V39, P713, DOI 10.1007/s00266-015-0550-4
   Gabriel A, 2019, PLAST RECONSTR SURG, V143, p36S, DOI 10.1097/PRS.0000000000005311
   Gabriel A, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001880
   Gerber B, 2015, DTSCH ARZTEBL INT, V112, P593, DOI 10.3238/arztebl.2015.0593
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Harbeck N, 2017, LANCET, V389, P1134, DOI [10.1016/s0140-6736(16)31891-8, 10.1016/S0140-6736(16)31891-8]
   Heimes AS, 2017, BREAST CARE, V12, P374, DOI 10.1159/000485234
   Irwin GW, 2020, PRS-GLOB OPEN, V8, DOI 10.1097/GOX.0000000000002667
   Jeevan R, 2014, J PLAST RECONSTR AES, V67, P1333, DOI 10.1016/j.bjps.2014.04.022
   Karami RA, 2020, ANN BREAST SURG, V4, P17, DOI [10.21037/abs-20-71, 10.21037/abs-20-71]
   Kim MJ, 2022, GLAND SURG, V11, P1, DOI 10.21037/gs-21-515
   Lalezari S, 2017, INT WOUND J, V14, P649, DOI 10.1111/iwj.12658
   Malekpour M, 2023, WORLD J CLIN CASES, V11, P2201, DOI 10.12998/wjcc.v11.i10.2201
   Menon G., 2025, StatPearls
   Michelotti BF, 2013, ANN PLAS SURG, V71, P274, DOI 10.1097/SAP.0b013e3182923dc9
   National Comprehensive Cancer Network, 2025, Breast Cancer
   Olsen MA, 2008, ARCH SURG-CHICAGO, V143, P53, DOI 10.1001/archsurg.2007.11
   Olsen MA, 2015, INFECT CONT HOSP EP, V36, P907, DOI 10.1017/ice.2015.108
   Panchal H, 2017, PLAST RECONSTR SURG, V140, p7S, DOI 10.1097/PRS.0000000000003941
   Rancati A, 2016, GLAND SURG, V5, P9, DOI 10.3978/j.issn.2227-684X.2015.08.01
   Regan JP., 2025, StatPearls
   Regnault P, 1976, Clin Plast Surg, V3, P193
   Shah A, 2019, ANN PLAS SURG, V82, pS222, DOI 10.1097/SAP.0000000000001842
   Siliprandi M, 2025, JPRAS OPEN, V44, P463, DOI [10.1016/j.jpra.2025.03.019, 10.1016/j.jpra.2025.03.019]
   Smith BD, 2017, JNCI-J NATL CANCER I, V109, DOI 10.1093/jnci/djw178
   Wagner RD, 2019, J PLAST RECONSTR AES, V72, P1051, DOI 10.1016/j.bjps.2019.04.005
   Washer LL, 2012, INFECT DIS CLIN N AM, V26, P111, DOI 10.1016/j.idc.2011.09.003
   Wilkins EG, 2018, ANN SURG, V267, P164, DOI 10.1097/SLA.0000000000002033
   Wilkins EG, 2000, PLAST RECONSTR SURG, V106, P1014, DOI 10.1097/00006534-200010000-00010
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Zhu MZ, 2024, MEDICINE, V103, DOI 10.1097/MD.0000000000037365
NR 44
TC 1
Z9 1
U1 1
U2 1
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1090-820X
EI 1527-330X
J9 AESTHET SURG J
JI Aesthet. Surg. J.
PD 2025 NOV 11
PY 2025
DI 10.1093/asj/sjaf211
EA NOV 2025
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 9SN4G
UT WOS:001613992000001
PM 41127926
OA hybrid
DA 2026-07-24
ER

PT J
AU Wang, T
   He, R
   Zhao, J
   Mei, JC
   Shao, MZ
   Pan, Y
   Zhang, J
   Wu, HS
   Yu, M
   Yan, WC
   Liu, LM
   Liu, F
   Jia, WP
AF Wang, T.
   He, R.
   Zhao, J.
   Mei, J. C.
   Shao, M. Z.
   Pan, Y.
   Zhang, J.
   Wu, H. S.
   Yu, M.
   Yan, W. C.
   Liu, L. M.
   Liu, F.
   Jia, W. P.
TI Negative pressure wound therapy inhibits inflammation and upregulates
   activating transcription factor-3 and downregulates nuclear factor-B in
   diabetic patients with foot ulcerations
SO DIABETES-METABOLISM RESEARCH AND REVIEWS
LA English
DT Article
DE ATF-3; diabetic foot; inflammation; negative pressure wound therapy;
   nuclear factor-B
ID NECROSIS-FACTOR-ALPHA; NITRIC-OXIDE; MULTICENTER; MECHANISMS; RESPONSES;
   PATHWAYS; BINDING; ULCERS
AB BackgroundNegative pressure wound therapy (NPWT) is one of the most important treatments for diabetic foot, but the underlying mechanisms of its benefits still remain elusive. This study aims to evaluate the inflammatory signals involved in the effects of negative pressure therapy on diabetic foot ulcers.
   MethodsWe enrolled 22 patients with diabetic foot ulceration, 11 treated with NPWT and the other 11 treated with traditional debridement. All patients were treated and observed for 1week. Granulation tissues were harvested and analyzed in both groups, and then were histologically and immunohistochemically analyzed. Enzyme-linked immunosorbent assay, Western blot analysis, and real-time PCR were performed to evaluate the expression of interleukin-6 (IL-6), tumor necrosis factor (TNF-), inducible nitric oxide synthase (iNOS), nuclear factor-B (NF-B) p65, IkB-, and activating transcription factor-3 (ATF-3).
   ResultsAfter 7days of treatment, NPWT could obviously promote diabetic wound healing because of the mild inflammation and the dense cell-deposited matrix. Meanwhile, NPWT significantly decreased the expression of TNF-, IL-6, and iNOS (all P<.05). The result of Western blotting and real-time PCR indicated that NPWT obviously decreased the level of IkB- and NF-B p65, and increased the level of ATF-3 (all P<.05).
   ConclusionNPWT exerts an anti-inflammatory effect, possibly through the suppression of proinflammatory enzymes and cytokines resulting from IkB- inhibition and ATF-3 activation, which may prevent the activation of the NF-B pathway in human diabetic foot wounds.
C1 [Wang, T.; Zhao, J.; Mei, J. C.; Shao, M. Z.; Pan, Y.; Zhang, J.; Wu, H. S.; Yu, M.; Yan, W. C.] Shanghai Jiao Tong Univ, Multidisciplinary Collaborat Ctr Diabet Foot, Shanghai Clin Med Ctr Diabet, Affiliated Peoples Hosp Shanghai 6,Dept Vasc Surg, 600 Yishan Rd, Shanghai 200233, Peoples R China.
   [He, R.; Liu, L. M.; Liu, F.; Jia, W. P.] Shanghai Jiao Tong Univ, Shanghai Clin Med Ctr Diabet,Shanghai Inst Diabet, Shanghai Key Clin Ctr Metab Dis,Affiliated People, Multidisciplinary Collaborat Grp Diabet Foot,Dept, Shanghai, Peoples R China.
C3 Shanghai Jiao Tong University; Shanghai Jiao Tong University
RP Zhao, J (通讯作者)，Shanghai Jiao Tong Univ, Multidisciplinary Collaborat Ctr Diabet Foot, Shanghai Clin Med Ctr Diabet, Affiliated Peoples Hosp Shanghai 6,Dept Vasc Surg, 600 Yishan Rd, Shanghai 200233, Peoples R China.; Liu, F (通讯作者)，Shanghai Jiao Tong Univ, Shanghai Clin Med Ctr Diabet,Shanghai Inst Diabet, Shanghai Key Clin Ctr Metab Dis,Affiliated People, Multidisciplinary Collaborat Grp Diabet Foot,Dept, Shanghai, Peoples R China.
EM junnzhao@126.com; f-liu@sjtu.edu.cn
RI 刘, 峰/KBA-6391-2024; He, Ruijia/MZQ-2297-2025; Jia, Weiping/B-7483-2012
OI Jia, Weiping/0000-0002-6244-2168
FU Natural Science Foundation of China [81270397]; Shanghai Health Bureau
   [201344197]
FX Natural Science Foundation of China, Grant/ Award Number: 81270397;
   Shanghai Health Bureau, Grant/Award Number: 201344197
CR Anwar MA, 2015, SCI REP-UK, V5, DOI 10.1038/srep07657
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Banwell P E, 2003, J Wound Care, V12, P22
   Barinov E F, 2010, Klin Khir, P40
   Basith S, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0054178
   Basith S, 2011, EXPERT OPIN THER PAT, V21, P927, DOI 10.1517/13543776.2011.569494
   Blakytny R, 2009, INT J LOW EXTR WOUND, V8, P95, DOI 10.1177/1534734609337151
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Borst SE, 2004, ENDOCRINE, V23, P177, DOI 10.1385/ENDO:23:2-3:177
   Chan YC, 2012, ARTERIOSCL THROM VAS, V32, P1372, DOI 10.1161/ATVBAHA.112.248583
   Falanga V, 2005, LANCET, V366, P1736, DOI 10.1016/S0140-6736(05)67700-8
   Ghosh S, 2002, CELL, V109, pS81, DOI 10.1016/S0092-8674(02)00703-1
   Hellmann J, 2015, PROSTAG OTH LIPID M, V116, P49, DOI 10.1016/j.prostaglandins.2015.01.001
   Keskek SO, 2014, PAK J MED SCI, V30, P968, DOI 10.12669/pjms.305.5182
   Kwon JW, 2015, SCI REP-UK, V5, DOI 10.1038/srep14470
   Latham KA, 2005, J IMMUNOL, V174, P3978, DOI 10.4049/jimmunol.174.7.3978
   Li CH, 2010, MOL CANCER, V9, DOI 10.1186/1476-4598-9-73
   Liu DH, 2014, CELL BIOCHEM BIOPHYS, V70, P539, DOI 10.1007/s12013-014-9953-0
   Lobmann R, 2005, DIABETES CARE, V28, P461, DOI 10.2337/diacare.28.2.461
   Manavalan B, 2010, PLOS ONE, V5, DOI 10.1371/journal.pone.0015782
   MCCOLL SR, 1990, J IMMUNOL, V145, P3047
   Murakami A, 2009, FORUM NUTR, V61, P193, DOI 10.1159/000212751
   Nishikori M, 2005, J CLIN EXP HEMATOP, V45, P15, DOI 10.3960/jslrt.45.15
   Ram M, 2015, EUR J PHARMACOL, V764, P9, DOI 10.1016/j.ejphar.2015.06.029
   Sano H, 2015, INT WOUND J, V12, P397, DOI 10.1111/iwj.12121
   Sepúlveda G, 2009, CIR ESPAN, V86, P171, DOI 10.1016/j.ciresp.2009.03.020
   Takeuchi O, 2010, CELL, V140, P805, DOI 10.1016/j.cell.2010.01.022
   Whitmore MM, 2007, J IMMUNOL, V179, P3622, DOI 10.4049/jimmunol.179.6.3622
   Wiwanitkit Viroj, 2013, J Cutan Aesthet Surg, V6, P173, DOI 10.4103/0974-2077.118436
NR 29
TC 32
Z9 32
U1 0
U2 17
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1520-7552
EI 1520-7560
J9 DIABETES-METAB RES
JI Diabetes-Metab. Res. Rev.
PD MAY
PY 2017
VL 33
IS 4
AR e2871
DI 10.1002/dmrr.2871
PG 9
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA ET8VO
UT WOS:000400581600005
DA 2026-07-24
ER

PT J
AU Simek, M
   Nemec, P
   Zalesak, B
   Hajek, R
   Kalab, M
   Jecminkova, L
AF Simek, M.
   Nemec, P.
   Zalesak, B.
   Hajek, R.
   Kalab, M.
   Jecminkova, L.
TI Negative pressure therapy as a treatment modality for surgical site
   infection in cardiac surgery
SO ACTA CHIRURGICA BELGICA
LA English
DT Article; Proceedings Paper
CT 9th Annual Conference of the European-Society-of-Surgery
CY NOV 12, 2005
CL Vienna, AUSTRIA
SP European Soc Surg
DE vacuum assisted closure; cardiac surgery; sternal infection;
   mediastinitis
ID VACUUM-ASSISTED CLOSURE; STERNAL WOUND-INFECTION; POSTSTERNOTOMY
   MEDIASTINITIS; POSTOPERATIVE MEDIASTINITIS; RISK-FACTORS; MICROBIOLOGY;
   MANAGEMENT; DRAINAGE
AB Background : Negative pressure therapy (NPT), primarily introduced for the treatment of pressure ulcers or chronic debilitating wounds, has recently emerged as a novel treatment strategy in the field of cardiac surgery, providing superior results to the conventional therapeutic strategies.
   Patients and methods : From November 2004 to October 2005, 25 patients underwent NPT (negative pressure therapy). Four patients (16%) were treated for extensive leg-wound infections, 10 (40%) were treated for superficial sternal wound infections and 11 (44%) for deep sternal wound infections. The median age was 67.9 years (range 48 to 79) and the median BMI was 34.2 kg/M-2 (range 28 to 41). Because of wound infection complications, 11 patients (44%) were re-admitted to the department. In 13 patients (52%), NPT was employed after the failure of the conventional treatment strategy.
   Results : All 25 patients were successfully healed. In-hospital mortality was 0% and 30-day survival was 100%. The overall length of hospitalization reached 36.4 days (range I I to 62). The median number of dressing changes was 4.9 (range 3 to 9). The median NPT treatment time until the surgical closure was 9.7 days (range 6 to 24 days). In 17 patients (68%), the excessive residual sternal defect required a local advancement flap transfer. One patient (4%) with a chronic wire-related fistula was re-admitted 6 months after NPT therapy.
   Conclusion : NPT therapy can be considered as an effective treatment strategy associated with a low risk of procedure failure and wound infection recurrence, particularly in the management of sternal wound infection after cardiac surgery.
C1 [Simek, M.; Nemec, P.; Hajek, R.; Kalab, M.; Jecminkova, L.] Univ Hosp, Dept Cardiac Surg, Olomouc 77520, Czech Republic.
   [Zalesak, B.] Univ Hosp, Dept Plast & Aesthet Surg, Olomouc 77520, Czech Republic.
   [Simek, M.; Nemec, P.; Zalesak, B.; Hajek, R.; Kalab, M.; Jecminkova, L.] Palacky Univ, Fac Med, CR-77147 Olomouc, Czech Republic.
C3 University Hospital Olomouc; University Hospital Olomouc; Palacky
   University Olomouc
RP Simek, M (通讯作者)，Univ Hosp, Dept Cardiac Surg, I P Pavlova 6, Olomouc 77520, Czech Republic.
EM martin.simek@c-mail.cz
RI Hajek, Roman/I-6639-2017
OI Hajek, Roman/0000-0001-6955-6267; Šimek, Martin/0000-0001-5377-2096
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Ascherman JA, 2004, PLAST RECONSTR SURG, V114, P676, DOI 10.1097/01.PRS.0000130939.32238.3B
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   Doss M, 2002, EUR J CARDIO-THORAC, V22, P934, DOI 10.1016/S1010-7940(02)00594-8
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Finkelstein R, 2005, AM J INFECT CONTROL, V33, P450, DOI 10.1016/j.ajic.2005.07.002
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Francel TJ, 2001, ANN THORAC SURG, V72, P1411, DOI 10.1016/S0003-4975(00)02008-7
   Fuchs U, 2005, ANN THORAC SURG, V79, P526, DOI 10.1016/j.athoracsur.2004.08.032
   Gårdlund B, 2002, EUR J CARDIO-THORAC, V21, P825, DOI 10.1016/S1010-7940(02)00084-2
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
   Immer FF, 2005, ANN THORAC SURG, V80, P957, DOI 10.1016/j.athoracsur.2005.03.035
   Kirsch M, 2001, ANN THORAC SURG, V71, P1580, DOI 10.1016/S0003-4975(01)02452-3
   KLETENSKY J, 2006, ACTA CHIRURGIAE PLAS, V1, P5
   Lepelletier D, 2005, INFECT CONT HOSP EP, V26, P466, DOI 10.1086/502569
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Mekontso-Dessap A, 2001, CLIN INFECT DIS, V32, P877, DOI 10.1086/319355
   Mendez-Eastman S, 1998, Plast Surg Nurs, V18, P27
   Raja Shahzad G, 2007, Interact Cardiovasc Thorac Surg, V6, P523, DOI 10.1510/icvts.2007.157370
   Ridderstolpe L, 2001, EUR J CARDIO-THORAC, V20, P1168, DOI 10.1016/S1010-7940(01)00991-5
   Scholl L, 2004, J CARDIAC SURG, V19, P453, DOI 10.1111/j.0886-0440.2004.05002.x
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjögren J, 2005, ANN THORAC SURG, V80, P1270, DOI 10.1016/j.athoracsur.2005.04.010
   Tegnell A, 2000, ANN THORAC SURG, V69, P1104, DOI 10.1016/S0003-4975(99)01563-5
NR 25
TC 2
Z9 3
U1 0
U2 6
PU ACTA MEDICAL BELGICA
PI BRUSSELS
PA AVENUE CIRCULAIRE 138 A, B-1180 BRUSSELS, BELGIUM
SN 0001-5458
J9 ACTA CHIR BELG
JI Acta Chir. Belg.
PD NOV-DEC
PY 2007
VL 107
IS 6
BP 653
EP 657
DI 10.1080/00015458.2007.11680141
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 250NR
UT WOS:000252307800010
PM 18274179
DA 2026-07-24
ER

PT J
AU Song, QC
   Li, D
   Zhao, Y
   Zhang, GY
   Shang, DL
   Fan, LH
   Dang, XQ
AF Song, Qi-Chun
   Li, Dong
   Zhao, Yan
   Zhang, Guang-Yang
   Shang, Dong-Long
   Fan, Li-Hong
   Dang, Xiao-Qian
TI Negative pressure wound therapy reduces the incidence of postoperative
   wound dehiscence and surgical site infections after total knee
   arthroplasty in patients with obesity
SO MEDICINE
LA English
DT Article
DE negative pressure wound treatment; obesity; surgical site infection;
   total knee replacement; wound dehiscence
ID COMPLICATION; HIP
AB Obesity is a risk factor for total knee arthroplasty (TKA). Wound dehiscence and surgical site infections (SSIs) are the main complications of TKA in patients with obesity. They can profoundly affect patients because they often require readmission, additional surgical interventions, lengthy intravenous antibiotic administration, and delayed rehabilitation. Negative pressure wound therapy (NPWT) exposes the wound site to negative pressure, resulting in the improvement of blood supply, removal of excess fluid, and stimulation of cellular proliferation of granulation tissue. This study aims to assess the incidence of wound dehiscence and SSIs in patients with obesity undergoing TKA after the routine use of NPWT. This sduty enrolled adult patients with obesity who underwent TKA within 8 years. A total of 360 adult patients with obesity (NPWT: 150, non-NPWT: 210) underwent TKA, and the baseline characteristics were similar between the 2 groups. Compared with the non-NPWT group, the NPWT group had a 50% lower incidence of wound dehiscence (3.33% vs 9.52%; P < .05) and a significantly lower incidence of SSIs (11.33% vs 25.24%; P < .05), including prosthetic joint infection (4.0% vs 10.0%; P < .05) and superficial wound infection (7.33% vs 15.24%; P < .05). In addition, the NPWT group had a lower need to return to the operating room for new interventions for any reason (2.67% vs 9.05%; P = .0107) than the non-NPWT group. Conventional incision NPWT can significantly reduce the incidence of wound dehiscence and SSIs in patients with obesity after TKA.
C1 [Song, Qi-Chun; Li, Dong; Zhao, Yan; Zhang, Guang-Yang; Shang, Dong-Long; Fan, Li-Hong; Dang, Xiao-Qian] Xi An Jiao Tong Univ, Affiliated Hosp 2, Xian, Peoples R China.
C3 Xi'an Jiaotong University
RP Dang, XQ (通讯作者)，Xi An Jiao Tong Univ, Affiliated Hosp 2, Dept Orthopaed, 157 Xiwu Rd, Xian 710004, Shaanxi, Peoples R China.
EM 2000bjjy@163.com; z578409218@163.com; guangyangz97@163.com;
   413526720@qq.com; zhibin_shi@126.com; xqdang@126.com
FU National Natural Science Foundation of China [82002311]; China
   Postdoctoral Science Foundation [2021M692575]
FX The present study was funded by the National Natural Science Foundation
   of China (grant no. 82002311) and China Postdoctoral Science Foundation
   (grant no. 2021M692575).
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   Amin AK, 2006, J BONE JOINT SURG BR, V88B, P1321, DOI 10.1302/0301-620X.88B10.17697
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bonds AM, 2013, DIS COLON RECTUM, V56, P1403, DOI 10.1097/DCR.0b013e3182a39959
   Borgquist O, 2010, PLAST RECONSTR SURG, V125, P502, DOI 10.1097/PRS.0b013e3181c82e1f
   Boyce L, 2019, ARCH ORTHOP TRAUM SU, V139, P553, DOI 10.1007/s00402-019-03127-5
   Brega C, 2021, WOUND REPAIR REGEN, V29, P848, DOI 10.1111/wrr.12914
   Gadinsky NE, 2012, J ARTHROPLASTY, V27, P1171, DOI 10.1016/j.arth.2011.12.012
   HORAN TC, 1992, INFECT CONT HOSP EP, V13, P606
   Järvenpää J, 2010, SCAND J SURG, V99, P45
   Kabon B, 2004, ANESTHESIOLOGY, V100, P274, DOI 10.1097/00000542-200402000-00015
   Kerkhoffs GMMJ, 2012, J BONE JOINT SURG AM, V94A, P1839, DOI 10.2106/JBJS.K.00820
   KRISHNAN EC, 1982, J SURG RES, V33, P89, DOI 10.1016/0022-4804(82)90012-9
   Malinzak RA, 2009, J ARTHROPLASTY, V24, P84, DOI 10.1016/j.arth.2009.05.016
   Mueller KB, 2021, NEUROSURGERY, V88, pE445, DOI 10.1093/neuros/nyab040
   Muenchow S, 2019, CLIN HEMORHEOL MICRO, V72, P365, DOI 10.3233/CH-180536
   Nherera LM, 2017, WOUND REPAIR REGEN, V25, P474, DOI 10.1111/wrr.12530
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Parvizi J, 2018, J ARTHROPLASTY, V33, P1309, DOI 10.1016/j.arth.2018.02.078
   Peersman G, 2006, HSS J, V2, P70, DOI 10.1007/s11420-005-0130-2
   Redfern RE, 2017, J ARTHROPLASTY, V32, P3333, DOI 10.1016/j.arth.2017.06.019
   Schwartz AM, 2020, J ARTHROPLASTY, V35, pS79, DOI 10.1016/j.arth.2020.02.030
   Shiroky J, 2020, SURGERY, V167, P1001, DOI 10.1016/j.surg.2020.01.018
   Wang TT, 2018, CYTOKINE GROWTH F R, V44, P38, DOI 10.1016/j.cytogfr.2018.10.002
   Ward DT, 2015, J ARTHROPLASTY, V30, P42, DOI 10.1016/j.arth.2015.03.045
   Webb Lawrence X, 2002, J Am Acad Orthop Surg, V10, P303
   Yaghmour Khaled M, 2020, J Bone Joint Surg Am, VPublish Ahead of Print, P541, DOI 10.2106/JBJS.20.01254
NR 27
TC 13
Z9 15
U1 0
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD JUL 8
PY 2022
VL 101
IS 27
AR e29641
DI 10.1097/MD.0000000000029641
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 2S8MX
UT WOS:000822042900013
PM 35801735
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Diehm, YF
   Fischer, S
   Wirth, GA
   Haug, V
   Orgill, DP
   Momeni, A
   Horch, RE
   Lehner, B
   Kneser, U
   Hirche, C
AF Diehm, Yannick F.
   Fischer, Sebastian
   Wirth, Garrett A.
   Haug, Valentin
   Orgill, Dennis P.
   Momeni, Arash
   Horch, Raymund E.
   Lehner, Burkhard
   Kneser, Ulrich
   Hirche, Christoph
TI Management of Acute and Traumatic Wounds With Negative-Pressure Wound
   Therapy With Instillation and Dwell Time
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID MICROSURGICAL RECONSTRUCTION; ANTISEPTIC SOLUTION; SALINE; DEFECTS;
   IMPACT; LEVEL; FOAM; LEG
AB Background: A promising and useful development of negative-pressure wound therapy (NPWT) is the addition of instillation and dwell time of topical wound solutions (NPWTi-d). Uses of NPWTi-d include acute and traumatic wounds, whereby wound closure may be facilitated via wound cleansing and promotion of granulation tissue formation. This systematic review summarizes publications on NPWTi-d in the treatment of acute and traumatic wounds.
   Methods: A systematic review was performed analyzing articles from major clinical databases. Only clinical studies >= 10 patients reporting on the application of NPWTi-d in acute and traumatic wounds were included.
   Results: One hundred ninety-two articles were retrieved, of which 10 articles met inclusion criteria. Of those, 2 were lesser-quality randomized controlled trials, comparative studies or prospective cohorts, 2 were retrospective studies, and 6 retrospective cohort studies. In total, included publications reported 109 patients with acute and traumatic wounds treated with NPWTi-d. Data from these studies indicated the potential for reduction in bacterial bioburden through wound cleansing and promotion of granulation tissue formation, thereby facilitating wound closure, reduced length of therapy and hospital time. However, for most publications, different wound causes and subsequently no isolated results for acute and traumatic wounds were reported.
   Conclusion: NPWTi-d has promise to be effective in facilitating wound closure and reducing the time for wound closure. The present systematic review demonstrates a relatively low level of evidence available to objectively support this effect. To underline these positive results, large prospective, randomized controlled trials are necessary to manifest the role of NPWTi-d in the daily clinical routine for this wound category.
C1 [Diehm, Yannick F.; Fischer, Sebastian; Wirth, Garrett A.; Haug, Valentin; Orgill, Dennis P.; Momeni, Arash; Horch, Raymund E.; Lehner, Burkhard; Kneser, Ulrich; Hirche, Christoph] Heidelberg Univ, Dept Hand Plast & Reconstruct Surg, Microsurg, Burn Trauma Ctr,BG Trauma Ctr Ludwigshafen, Ludwig Guttmann Str 13, D-67071 Ludwigshafen, Germany.
   [Diehm, Yannick F.; Fischer, Sebastian; Wirth, Garrett A.; Haug, Valentin; Orgill, Dennis P.; Momeni, Arash; Horch, Raymund E.; Lehner, Burkhard; Kneser, Ulrich; Hirche, Christoph] Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Div Plast Surg, Boston, MA 02115 USA.
   [Diehm, Yannick F.; Fischer, Sebastian; Wirth, Garrett A.; Haug, Valentin; Orgill, Dennis P.; Momeni, Arash; Horch, Raymund E.; Lehner, Burkhard; Kneser, Ulrich; Hirche, Christoph] Wirth Plast Surg, Newport Beach, CA USA.
   [Diehm, Yannick F.; Fischer, Sebastian; Wirth, Garrett A.; Haug, Valentin; Orgill, Dennis P.; Momeni, Arash; Horch, Raymund E.; Lehner, Burkhard; Kneser, Ulrich; Hirche, Christoph] Stanford Univ, Sch Med, Div Plast & Reconstruct Surg, Hagey Lab Pediat Regenerat Med, Palo Alto, CA 94304 USA.
   [Diehm, Yannick F.; Fischer, Sebastian; Wirth, Garrett A.; Haug, Valentin; Orgill, Dennis P.; Momeni, Arash; Horch, Raymund E.; Lehner, Burkhard; Kneser, Ulrich; Hirche, Christoph] Friedrich Alexander Univ, Univ Hosp Erlangen, Dept Plast & Hand Surg, Erlangen, Germany.
   [Diehm, Yannick F.; Fischer, Sebastian; Wirth, Garrett A.; Haug, Valentin; Orgill, Dennis P.; Momeni, Arash; Horch, Raymund E.; Lehner, Burkhard; Kneser, Ulrich; Hirche, Christoph] Friedrich Alexander Univ, Univ Hosp Erlangen, Lab Tissue Engn & Regenerat Med, Erlangen, Germany.
   [Diehm, Yannick F.; Fischer, Sebastian; Wirth, Garrett A.; Haug, Valentin; Orgill, Dennis P.; Momeni, Arash; Horch, Raymund E.; Lehner, Burkhard; Kneser, Ulrich; Hirche, Christoph] Orthoped Univ Hosp, Dept Orthoped Oncol & Sept Orthoped Surg, Ludwigshafen, Germany.
C3 Ruprecht Karls University Heidelberg; Harvard University; Harvard
   Medical School; Harvard University Medical Affiliates; Brigham & Women's
   Hospital; Stanford University; University of Erlangen Nuremberg;
   University of Erlangen Nuremberg
RP Hirche, C (通讯作者)，Heidelberg Univ, Dept Hand Plast & Reconstruct Surg, Microsurg, Burn Trauma Ctr,BG Trauma Ctr Ludwigshafen, Ludwig Guttmann Str 13, D-67071 Ludwigshafen, Germany.
EM Christoph.Hirche@bgu-ludwigshafen.de
RI Momeni, Arash/AAV-8300-2020; Orgill, Dennis/H-7596-2019; Fischer,
   Sebastian/AEX-5429-2022; Horch, Raymund/H-8128-2019
OI Momeni, Arash/0000-0002-6452-751X; 
CR Blalock L, 2019, WOUNDS, V31, P55
   Brinkert D, 2013, INT WOUND J, V10, P56, DOI 10.1111/iwj.12176
   Chowdhry SA, 2019, PRS-GLOB OPEN, V7, DOI 10.1097/GOX.0000000000002087
   Diehm YF, 2020, INT WOUND J, V17, P1740, DOI 10.1111/iwj.13462
   Eckstein FM, 2019, J CRANIO MAXILL SURG, V47, P389, DOI 10.1016/j.jcms.2018.12.006
   Fleischmann W, 1998, UNFALLCHIRURG, V101, P649, DOI 10.1007/s001130050318
   Fluieraru S, 2013, J WOUND CARE, V22, P293, DOI 10.12968/jowc.2013.22.6.293
   Gabriel A., 2014, Eplasty, V14
   Gabriel A, 2008, INT WOUND J, V5, P399, DOI 10.1111/j.1742-481X.2007.00423.x
   Glass GE, 2017, J PLAST RECONSTR AES, V70, P1028, DOI 10.1016/j.bjps.2017.05.027
   Goss S G, 2012, J Am Coll Clin Wound Spec, V4, P74, DOI 10.1016/j.jccw.2014.02.001
   GOTTLIEB LJ, 1994, PLAST RECONSTR SURG, V93, P1503, DOI 10.1097/00006534-199406000-00027
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Horch RE, 2020, EXPERT REV MED DEVIC, V17, P139, DOI 10.1080/17434440.2020.1714434
   Horch RE, 2018, ZBL CHIR, V143, P609, DOI 10.1055/a-0713-0517
   Kim PJ, 2020, INT WOUND J, V17, P174, DOI 10.1111/iwj.13254
   Kim PJ, 2015, PLAST RECONSTR SURG, V136, p657E, DOI 10.1097/PRS.0000000000001709
   Kim PJ, 2014, PLAST RECONSTR SURG, V133, P709, DOI 10.1097/01.prs.0000438060.46290.7a
   Kim PJ, 2015, Wounds, V27, pS2
   Lane Jennifer Ce, 2012, Open Orthop J, V6, P511, DOI 10.2174/1874325001206010511
   Leaper DJ, 2006, BMJ-BRIT MED J, V332, P532, DOI 10.1136/bmj.332.7540.532
   Lehner B, 2011, INT ORTHOP, V35, P1415, DOI 10.1007/s00264-011-1274-y
   Lessing C, 2011, WOUNDS, V23, P309
   Ludolph I, 2018, INT WOUND J, V15, P978, DOI 10.1111/iwj.12958
   Orgill DP, 2013, INT WOUND J, V10, P15, DOI 10.1111/iwj.12170
   Schintler MV, 2009, INFECTION, V37, P31
   Sullivan D, 2011, PLAST RECONSTR SURG, V128, P311, DOI 10.1097/PRS.0b013e3182195826
   Timmers MS, 2009, WOUND REPAIR REGEN, V17, P278, DOI 10.1111/j.1524-475X.2009.00458.x
   Xiong LY, 2018, J PLAST RECONSTR AES, V71, P273, DOI 10.1016/j.bjps.2017.10.018
   Xiong LY, 2016, INJURY, V47, P2558, DOI 10.1016/j.injury.2016.09.010
   Xiong LY, 2016, MICROSURG, V36, P511, DOI 10.1002/micr.30020
   Yang CK, 2015, J VASC SURG, V61, P995, DOI 10.1016/j.jvs.2014.11.076
NR 32
TC 25
Z9 29
U1 2
U2 14
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JAN
PY 2021
VL 147
IS 1S-1
SU WOUND THER
BP 43S
EP 53S
DI 10.1097/PRS.0000000000007610
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA TB6XV
UT WOS:000668089500008
PM 33347062
DA 2026-07-24
ER

PT J
AU de Vries, FEE
   Atema, JJ
   Lapid, O
   Obdeijn, MC
   Boermeester, MA
AF de Vries, F. E. E.
   Atema, J. J.
   Lapid, O.
   Obdeijn, M. C.
   Boermeester, M. A.
TI Closed incision prophylactic negative pressure wound therapy in patients
   undergoing major complex abdominal wall repair
SO HERNIA
LA English
DT Article
DE Complex abdominal wall repair; Prophylactic negative pressure
ID ACELLULAR DERMAL MATRIX; VENTRAL HERNIA REPAIRS; STAGE REPAIR;
   RECONSTRUCTION; DEFECTS; EXPERIENCE; MANAGEMENT; COST; MESH
AB Purpose To evaluate if incisional prophylactic negative pressure wound therapy (pNPWT) reduces wound infections and other wound complications in high-risk patients undergoing major complex ventral abdominal wall repair.
   Methods Retrospective before-after comparison nested in a consecutive series of patients undergoing elective major complex abdominal wall repair. Starting January 2014, pNPWT was applied on the closed incisional wound for a minimum of 5 days. To minimize selection bias, we compared two periods of 14 months before and after January 2014. Wound infections according to the Centre for Disease Control Surgical Site Infection classification as well as other wound complications were recorded.
   Results Thirty-two patients were included in the pNPWT group and 34 in the control group. The study group involved clean-contaminated and contaminated operations due to enterocutaneous fistula, enterostomies or infected mesh. Median duration of pNPWT was 5 days (IQR 5-7). Overall wound infection rate was 35%. pNPWT was associated with a significant decrease in postoperative wound infection rate (24 versus 51%; p = 0.029, OR 0.30 (95% CI 0.10-0.90)). Incisional wound infection rates dropped from 48 to 7% (p < 0.01, OR 0.08 (95% CI 0.16-0.39), whereas the number of subcutaneous abscesses was comparable in both groups. Moreover, less interventions were needed in the pNPWT group (p < 0.001).
   Conclusions Closed incision pNPWT seems a promising solution to reduce the incidence of wound infections in complex abdominal wall surgery. Randomized controlled trials are needed to estimate more precisely the value and cost-effectiveness of pNPWT in this high-risk setting.
C1 [de Vries, F. E. E.; Atema, J. J.; Boermeester, M. A.] Acad Med Ctr, Dept Surg, POB 22660, NL-1100 DD Amsterdam, Netherlands.
   [Atema, J. J.] Onze Lieve Vrouw Hosp, Dept Surg, Amsterdam, Netherlands.
   [Lapid, O.; Obdeijn, M. C.] Acad Med Ctr, Dept Plast & Reconstruct Surg, Amsterdam, Netherlands.
C3 University of Amsterdam; Academic Medical Center Amsterdam; Onze Lieve
   Vrouwe Gasthuis Hospital; University of Amsterdam; Academic Medical
   Center Amsterdam
RP de Vries, FEE (通讯作者)，Acad Med Ctr, Dept Surg, POB 22660, NL-1100 DD Amsterdam, Netherlands.
EM f.e.devries@amc.uva.nl
RI Lapid, Oren/S-6331-2019
OI Lapid, Oren/0000-0001-8921-9866; Boermeester, Marja/0000-0003-3890-8105
CR Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe288, DOI 10.1016/S1473-3099(16)30402-9
   [Anonymous], 2014, CADTH Rapid Response Reports
   [Anonymous], 2015, STD Facts - Congenital Syphilis, P1
   [Anonymous], LANCET INFECT DIS
   [Anonymous], ANN PLAST SURG
   Basta MN, 2015, AM J SURG, V209, P695, DOI 10.1016/j.amjsurg.2014.04.017
   Borgquist O, 2011, OSTOMY WOUND MANAG, V57, P44
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   Echebiri NC, 2015, OBSTET GYNECOL, V125, P299, DOI 10.1097/AOG.0000000000000634
   Garvey PB, 2014, J AM COLL SURGEONS, V219, P853, DOI 10.1016/j.jamcollsurg.2014.06.021
   Gassman A, 2015, HERNIA, V19, P273, DOI 10.1007/s10029-014-1312-y
   Iacco A, 2014, AM J SURG, V208, P480, DOI 10.1016/j.amjsurg.2013.09.020
   Itani KMF, 2012, SURGERY, V152, P498, DOI 10.1016/j.surg.2012.04.008
   Kanters AE, 2012, J AM COLL SURGEONS, V215, P787, DOI 10.1016/j.jamcollsurg.2012.08.012
   Kim H, 2006, AM J SURG, V192, P705, DOI 10.1016/j.amjsurg.2006.09.003
   Lewis LS, 2014, GYNECOL ONCOL, V132, P684, DOI 10.1016/j.ygyno.2014.01.014
   Meissner K, 1999, DIGEST SURG, V16, P169, DOI 10.1159/000018721
   Pauli EM, 2013, SURG INFECT, V14, P270, DOI 10.1089/sur.2012.059
   Pinell-White XA, 2014, ANN PLAS SURG, V72, pS150, DOI 10.1097/SAP.0000000000000100
   Roberts DJ, 2012, J TRAUMA ACUTE CARE, V73, P629, DOI 10.1097/TA.0b013e31825c130e
   Rosen MJ, 2013, ANN SURG, V257, P991, DOI 10.1097/SLA.0b013e3182849871
   Semsarzadeh NN, 2015, PLAST RECONSTR SURG, V136, P592, DOI 10.1097/PRS.0000000000001519
   Slater NJ, 2014, HERNIA, V18, P7, DOI 10.1007/s10029-013-1168-6
   Slater NJ, 2015, ANN SURG, V261, P553, DOI 10.1097/SLA.0000000000000733
   Soares KC, 2015, AM J SURG, V209, P324, DOI 10.1016/j.amjsurg.2014.06.022
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Tuffaha HW, 2015, J SURG RES, V195, P612, DOI 10.1016/j.jss.2015.02.008
NR 27
TC 42
Z9 44
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1265-4906
EI 1248-9204
J9 HERNIA
JI Hernia
PD AUG
PY 2017
VL 21
IS 4
BP 583
EP 589
DI 10.1007/s10029-017-1620-0
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FB3IQ
UT WOS:000406036600013
PM 28534258
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Nabata, KJ
   Rai, S
   Zhao, DR
   Macneill, AJ
   Hamilton, TD
AF Nabata, Kylie J.
   Rai, Sabrina
   Zhao, Darren
   Macneill, Andrea J.
   Hamilton, Trevor D.
TI Negative Pressure Wound Therapy to Reduce Surgical Site Infections after
   CRS/HIPEC
SO ANNALS OF SURGICAL ONCOLOGY
LA English
DT Article
ID LAPAROTOMY; SURGERY; TRIAL
AB Background. Surgical site infections (SSIs) are a common cause of morbidity after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal malignancy. Negative pressure wound therapy (NPWT) has been proposed as a method to reduce the rates of SSIs; however, there is paucity in the literature on the efficacy in this population. The goal of this study was to determine whether routine use of NPWT in patients undergoing CRS/HIPEC could reduce the risk of developing SSI. Methods. We performed a retrospective before-after study to assess the rates of SSI with NPWT compared with a standard postoperative surgical dressing (SSD) in all patients undergoing CRS/HIPEC from November 2013 to December 2021 at a single tertiary care center. The primary outcome was rate of SSI. A multivariate logistic regression analysis was performed to evaluate for risk factors for SSI. Results. A total of 178 patients were treated with CRS/HIPEC over the study period. Seventy patients had placement of SSD, and 108 patients had placement of NPWT. Rates of SSI were 11.4% (8/70) and 5.6% (6/108) in the two groups, respectively (p = 0.16). On multivariate analysis, patients treated with NPWT had a significantly lower risk of developing an SSI (OR 0.24 [0.06, 0.92], p = 0.037). Patients living >50 km from the hospital had significantly higher risk of developing SSI (OR 2.03 [1.09, 3.78], p = 0.026). Conclusions. These results suggest that routine use of NPWT can reduce the risk of developing an SSI in patients undergoing CRS/HIPEC for peritoneal malignancy.
C1 [Nabata, Kylie J.; Rai, Sabrina; Zhao, Darren; Macneill, Andrea J.; Hamilton, Trevor D.] Univ British Columbia, Gordon & Leslie Diamond Hlth Care Ctr, Dept Surg, Vancouver, BC, Canada.
C3 University of British Columbia
RP Hamilton, TD (通讯作者)，Univ British Columbia, Gordon & Leslie Diamond Hlth Care Ctr, Dept Surg, Vancouver, BC, Canada.
EM trevor.hamilton@vch.ca
CR Alyami M, 2018, INT J HYPERTHER, V34, P532, DOI 10.1080/02656736.2017.1367846
   BERARD F, 1964, Ann Surg, V160, P1
   Blackham AU, 2013, AM J SURG, V205, P647, DOI 10.1016/j.amjsurg.2012.06.007
   Boland PA, 2021, IRISH J MED SCI, V190, P261, DOI 10.1007/s11845-020-02283-7
   BOYCE JM, 1990, INFECT CONT HOSP EP, V11, P89
   CDC N, 2021, SURG SITE INFECT EVE
   Foster JM, 2019, JAMA NETW OPEN, V2, DOI 10.1001/jamanetworkopen.2018.6847
   Gupta N, 2019, J ANAESTH CLIN PHARM, V35, P3, DOI 10.4103/joacp.JOACP_93_18
   Holm C, 1998, EUR J SURG, V164, P179
   Jedrzejko N, 2022, J GASTROINTEST SURG, V26, P2176, DOI 10.1007/s11605-022-05394-x
   Kubek EW, 2013, FORMATEX
   LAU WY, 1986, BJS-BRIT J SURG, V73, P958, DOI 10.1002/bjs.1800731205
   Lawrence SA, 2019, J AM COLL SURGEONS, V228, P595, DOI 10.1016/j.jamcollsurg.2018.12.018
   Lynam S, 2016, INT J GYNECOL CANCER, V26, P1525, DOI 10.1097/IGC.0000000000000792
   Mark KS, 2014, SURG INNOV, V21, P345, DOI 10.1177/1553350613503736
   Mohiuddin K, 2013, J SURG ONCOL, V108, P315, DOI 10.1002/jso.23398
   Nguyen NT, 2002, J AM COLL SURGEONS, V194, P557, DOI 10.1016/S1072-7515(02)01132-8
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   O'Neill CH, 2020, J SURG ONCOL, V122, P480, DOI 10.1002/jso.25980
   Orgill DP, 2013, INT WOUND J, V10, P15, DOI 10.1111/iwj.12170
   Othman D, 2012, PLAST SURG INT
   Perencevich EN, 2003, EMERG INFECT DIS, V9, P196
   Pinkney TD., 2013, BMJ, V347
   POULSEN KB, 1994, EPIDEMIOL INFECT, V113, P283, DOI 10.1017/S0950268800051712
   Putri IL, 2022, INT WOUND J, V19, P1578, DOI 10.1111/iwj.13756
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Serra F, 2019, G CHIR, V40, P578
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Smibert OC, 2020, SUPPORT CARE CANCER, V28, P2745, DOI 10.1007/s00520-019-05093-5
   Stannard JP, 2012, INT WOUND J, V9, P32, DOI 10.1111/j.1742-481X.2012.01017.x
   Vallicelli C, 2022, ANTIBIOTICS-BASEL, V11, DOI 10.3390/antibiotics11010043
   Varela JE, 2010, SURG ENDOSC, V24, P270, DOI 10.1007/s00464-009-0569-1
   VEGAS AA, 1993, EUR J EPIDEMIOL, V9, P504
   Whelan RL, 2003, SURG ENDOSC, V17, P972, DOI 10.1007/s00464-001-8263-y
   Wichmann MW, 2005, ARCH SURG-CHICAGO, V140, P692, DOI 10.1001/archsurg.140.7.692
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
NR 37
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1068-9265
EI 1534-4681
J9 ANN SURG ONCOL
JI Ann. Surg. Oncol.
PD JUL
PY 2024
VL 31
IS 7
BP 4735
EP 4740
DI 10.1245/s10434-024-15283-z
EA APR 2024
PG 6
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA TU9J9
UT WOS:001207153500004
PM 38653941
DA 2026-07-24
ER

PT J
AU Katsumi, S
   Shinohara, A
   Kajiwara, T
   Saito, M
AF Katsumi, Shunsuke
   Shinohara, Akira
   Kajiwara, Takayoshi
   Saito, Mitsuru
TI Tension Pneumocephalus Associated with Negative Pressure Wound Therapy
   with Instillation and Dwell Time for Methicillin-resistant
   Staphylococcus aureus Infection After Spinal Deformity Surgery
SO EUROPEAN SPINE JOURNAL
LA English
DT Article
DE Pneumocephalus; NPWTi-d; Adult spinal deformity; SSI; MRSA; Spine
   surgery
ID COMPLICATION; TRENDS
AB Purpose Surgical site infection (SSI) is a serious complication after spine surgery. Recently, it has become possible to perform negative pressure wound therapy with instillation and dwell time (NPWTi-d) for postoperative infected wounds. We report the first rare case of symptomatic pneumoencephalopathy following NPWTi-d for methicillin-resistant Staphylococcus aureus (MRSA) infection after spinal deformity surgery. Methods Retrospective review of a patient's medical record and imaging. Results A 77-year-old female patient underwent posterior corrective fixation with no intraoperative complications. On the 10th postoperative day, SSI was diagnosed, and debridement was performed. Since MRSA was detected in the wound culture, and a prolonged inflammatory reaction was observed, NPWTi-d was started to preserve the instrumentation. Gradually, good granulation was observed, and the extensive soft tissue defect decreased. On the 29th day after the start of NPWTi-d, the patient experienced sudden headache and neck pain while standing, and head computed tomography led to the diagnosis of symptomatic pneumoencephalopathy. NPWTi-d was discontinued, and when surgery was performed to close the wound, dural injury was found, which was not present at the time of the initial surgery, and dural repair was performed. After 2 weeks of bed rest, the patient's pneumoencephalopathy improved. Three years have passed since the surgery, and no recurrence of cerebrospinal fluid leakage or infection has been observed. Conclusions Although NPWTi-d is a useful treatment for SSI, it is always necessary to pay attention to the development of pneumoencephalopathy and promptly diagnose and treat it because of the risk of life-threatening complications.
C1 [Katsumi, Shunsuke; Shinohara, Akira; Kajiwara, Takayoshi; Saito, Mitsuru] Jikei Univ, Sch Med, Dept Orthopaed Surg, Minato Ku, 3-19-18 Nishi Shinbashi, Tokyo 1058471, Japan.
C3 Jikei University
RP Katsumi, S (通讯作者)，Jikei Univ, Sch Med, Dept Orthopaed Surg, Minato Ku, 3-19-18 Nishi Shinbashi, Tokyo 1058471, Japan.
EM shnskktsm@gmail.com
OI Katsumi, Shunsuke/0000-0003-1682-2749; Saito,
   Mitsuru/0000-0003-1653-4309
CR Alluri R, 2020, SPINE, V45, pE155, DOI 10.1097/BRS.0000000000003213
   Anderson DJ, 2009, PLOS ONE, V4, DOI 10.1371/journal.pone.0008305
   Ayberk G, 2010, J CLIN NEUROSCI, V17, P934, DOI 10.1016/j.jocn.2009.10.033
   Canavese F, 2018, ARCH ORTHOP TRAUM SU, V138, P463, DOI 10.1007/s00402-017-2860-2
   Gauthé R, 2016, ORTHOP TRAUMATOL-SUR, V102, P251, DOI 10.1016/j.otsr.2015.12.006
   Hartig D, 2008, ANZ J SURG, V78, P812, DOI 10.1111/j.1445-2197.2008.04657.x
   Hrasovec Samo, 2020, Wounds, V32, pE71
   Huang C, 2014, J CLIN NEUROSCI, V21, P323, DOI 10.1016/j.jocn.2012.10.044
   Kobayashi K, 2020, SPINE, V45, P1459, DOI 10.1097/BRS.0000000000003545
   Kundangar RS, 2021, BMJ CASE REP, V14, DOI 10.1136/bcr-2020-239694
   Mehbod AA, 2005, J SPINAL DISORD TECH, V18, P14, DOI 10.1097/01.bsd.0000133493.32503.d3
   Ozturk E, 2006, ACTA RADIOL, V47, P497, DOI 10.1080/02841850600644766
   Schirmer CM, 2010, NEUROCRIT CARE, V13, P152, DOI 10.1007/s12028-010-9363-0
   Sugawara R, 2021, J ORTHOP SCI, V26, P533, DOI 10.1016/j.jos.2020.05.006
   West JM, 2018, ADV WOUND CARE, V7, P333, DOI 10.1089/wound.2018.0793
   Zhao Y, 2021, MEDICINE, V100, DOI 10.1097/MD.0000000000026322
   Zhou JM, 2020, SPINE, V45, P208, DOI 10.1097/BRS.0000000000003218
NR 17
TC 2
Z9 5
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0940-6719
EI 1432-0932
J9 EUR SPINE J
JI Eur. Spine J.
PD DEC
PY 2022
VL 31
IS 12
BP 3776
EP 3781
DI 10.1007/s00586-022-07367-9
EA SEP 2022
PG 6
WC Clinical Neurology; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Orthopedics
GA 8H0RE
UT WOS:000849447700001
PM 36056966
DA 2026-07-24
ER

PT J
AU Simsek, A
AF Simsek, Arife
TI Thigh Abscess Secondary to Intra-abdominal Pathologic Conditions: Three
   Cases Progressing to Necrotizing Fasciitis
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE thigh abscess; necrotizing fasciitis; debridement; intra-abdominal
   pathologic condition; negative pressure wound therapy; enterocutaneous
   fistula
ID RETROPERITONEAL; PERFORATION
AB Introduction. Necrotizing fasciitis results in progressive destruction of the fascia and overlying tissue. Mortality primarily depends upon the timing of medical care and the extent of infection. Objective. This article presents a case series of thigh abscesses originating from intra-abdominal pathologic conditions and progressing to necrotizing fasciitis due to delayed diagnosis. Materials and Methods. The data concerning 3 patients with thigh abscess originating from an intra-abdominal pathologic condition and progressing to necrotizing fasciitis are presented. Results. All patients had undergone previous colorectal surgery for malignancy and were admitted to the hospital with pain concentrated in the lower back and spreading down to the buttock, sacrum and coccyx, and leg. Patients had received symptomatic therapy, including nonsteroidal anti-inflammatory drugs, and 1 patient had undergone diskectomy for a herniated disk in the lumbar region. All 3 patients subsequently developed thigh abscesses (initially treated by percutaneous and/or surgical drainage) and received antibiotic therapy. One patient underwent percutaneous drainage, and 2 patients underwent abdominal surgery to address the abdominal abscess. During the course of treatment, thigh abscesses progressed to necrotizing fasciitis, which was treated by surgical debridement with or without negative pressure wound therapy. All patients died of overwhelming sepsis. Conclusions. Thigh abscess may spontaneously arise from surrounding soft tissues, or it may be a sign of intraperitoneal, retroperitoneal, or pelvic pathologic conditions. Deep, vague pain in the back or hip area that spreads downward to the buttock and leg may be an early symptom of these pathologic conditions. Clinical suspicion may be effective in reducing mortality by enabling early surgical intervention, especially in the patient with a previous history of abdominal surgery, radiotherapy, or inflammatory or malignant disease.
C1 [Simsek, Arife] Inonu Univ, Sch Med, Dept Gen Surg, TR-44100 Malatya, Turkey.
C3 Inonu University
RP Simsek, A (通讯作者)，Inonu Univ, Sch Med, Dept Gen Surg, TR-44100 Malatya, Turkey.
EM draksimsek@yahoo.com.tr
RI Simsek, Arife/AAB-3245-2021
CR Cacurri A, 2014, CASE REP SURG, V2014, DOI 10.1155/2014/128506
   Capobianco Claire M, 2009, Clin Podiatr Med Surg, V26, P619, DOI 10.1016/j.cpm.2009.08.002
   Hahn HM, 2018, ANN SURG TREAT RES, V95, P324, DOI 10.4174/astr.2018.95.6.324
   Hsieh CH, 2006, WORLD J GASTROENTERO, V12, P496, DOI 10.3748/wjg.v12.i3.496
   Hsu WH, 2014, SURG INFECT, V15, P467, DOI 10.1089/sur.2012.008
   Lal S, 2012, J CLIN DIAGN RES, V6, P457
   LINSCHEID RL, 1963, J BONE JOINT SURG AM, V45, P1691, DOI 10.2106/00004623-196345080-00013
   MAIR WSJ, 1977, BRIT J SURG, V64, P205, DOI 10.1002/bjs.1800640317
   Morgan MS, 2010, J HOSP INFECT, V75, P249, DOI 10.1016/j.jhin.2010.01.028
   ROTSTEIN OD, 1986, AM J SURG, V151, P414, DOI 10.1016/0002-9610(86)90481-2
   Saldua NS, 2010, CLIN ORTHOP RELAT R, V468, P619, DOI 10.1007/s11999-009-1015-3
   Simsek A, 2020, ARCH HELL MED, V37, P650
   Stevens DL, 2017, NEW ENGL J MED, V377, P2253, DOI 10.1056/NEJMra1600673
NR 13
TC 2
Z9 3
U1 0
U2 1
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD SEP
PY 2021
VL 33
IS 9
BP 226
EP 230
DI 10.25270/wnds/2021.226230
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA WT5BS
UT WOS:000715879600002
PM 34734841
DA 2026-07-24
ER

PT J
AU Glass, GE
   Jain, A
AF Glass, G. E.
   Jain, A.
TI Pretibial lacerations: Experience from a lower limb trauma centre and
   systematic review
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Review
DE Pretibial laceration; Haematoma; Management; Dunkin classification;
   Elderly
ID SKIN-GRAFTS; MANAGEMENT; INJURY; MOBILIZATION; HEMATOMAS; THICKNESS;
   CLOSURE; WOUNDS
AB Background: Pretibial lacerations are an important and neglected problem among the elderly. Poor management leads to prolonged hospitalisation and terminal decline. This study summarises our experience and evidence from the literature to ascertain an evidence-based rationale for referral and management.
   Methods: Our data were obtained from review of a prospectively gathered database. Additionally, Pubmed, Embase, Medline, and the Cochrane Database of Systematic Reviews were searched through July 2013, with eligible studies evaluated using standard methodology.
   Results: Seventy-three pretibial lacerations in 73 patients (63 females) were identified. Mean age was 78 +/- 14, 1SD. Sixty patients were managed operatively with a mean length of stay of 11 +/- 7 days, 1SD when uncomplicated by medical co-morbidity. Seven deaths occurred (4 in-hospital; 2 treated surgically and 2 treated conservatively) and 3 deaths occurred within 3 months of discharge; a death rate more than twice that of matched controls. Donor site "over-grafting" was performed in 19 cases and resulted in accelerated donor site healing (11 +/- 9 days, 1SD vs. 29 +/- 42 days, 1SD; P < 0.001). Negative pressure wound therapy delayed discharge (21 +/- 23 days, 1SD vs. 15 +/- 14 days, 1SD; P = 0.028). Microbiological sampling is unhelpful. Bed rest is unnecessary. "De-fatting" the flap is unproven.
   Conclusion: Admissions expose the elderly to physical/functional decline and death. Our findings support a change of practice, minimising admissions for minor (Dunkin type I/II) injuries and rapid, protocol-driven surgical intervention and discharge for Dunkin type III/IV injuries with avoidance of negative pressure wound therapy in all but selected cases. (C) 2014 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Glass, G. E.; Jain, A.] Univ Oxford, Kennedy Inst Rheumatol, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford OX3 7FY, England.
   [Jain, A.] Imperial Coll NHS Fountat Trust, Charing Cross Hosp, Dept Plast & Reconstruct Surg, London W6 8RF, England.
C3 University of Oxford; Kennedy Institute for Rheumatology; Imperial
   College London
RP Jain, A (通讯作者)，Imperial Coll NHS Fountat Trust, Charing Cross Hosp, Dept Plast Surg, Fulham Palace Rd, London W6 8RF, England.
EM ajainuk@aol.com
RI Glass, Graeme/I-7011-2019
FU Academy of Medical Sciences; Academy of Medical Sciences (AMS)
   [AMS-SGCL6-Glass] Funding Source: researchfish
FX GG is in receipt of a grant from the Academy of Medical Sciences for
   work unrelated to this study.
CR [Anonymous], NURS STAND
   [Anonymous], NURS STAND
   Beldon Pauline, 2008, Nurs Stand, V22, P53
   BODENHAM D C, 1971, British Journal of Plastic Surgery, V24, P20, DOI 10.1016/S0007-1226(71)80005-X
   BUDNY PG, 1993, BRIT J PLAST SURG, V46, P594, DOI 10.1016/0007-1226(93)90113-P
   CRAWFORD BS, 1977, BRIT J PLAST SURG, V30, P174, DOI 10.1016/0007-1226(77)90019-4
   CREDITOR MC, 1993, ANN INTERN MED, V118, P219, DOI 10.7326/0003-4819-118-3-199302010-00011
   Davis A, 2004, J Wound Care, V13, P5
   Dunkin C S J, 2003, J Wound Care, V12, P109
   FATAH MF, 1984, BRIT J PLAST SURG, V37, P184, DOI 10.1016/0007-1226(84)90008-0
   Foroughi D, 1990, J R Coll Surg Edinb, V35, P245
   Glass GE, 2011, J PLAST RECONSTR AES, V64, P375, DOI 10.1016/j.bjps.2010.05.037
   Glass GE, 2012, J PLAST RECONSTR AES, V65, P903, DOI 10.1016/j.bjps.2011.12.014
   GRANT DA, 1993, BRIT J GEN PRACT, V43, P174
   HAIART DC, 1990, BRIT J PLAST SURG, V43, P312, DOI 10.1016/0007-1226(90)90078-E
   Harris Connie L, 2004, Ostomy Wound Manage, V50, P54
   Higgins JPT, 2011, BMJ-BRIT MED J, V343, DOI 10.1136/bmj.d5928
   Ibuki A, 2012, EXP DERMATOL, V21, P178, DOI 10.1111/j.1600-0625.2011.01409.x
   JONES BM, 1983, BMJ-BRIT MED J, V286, P502, DOI 10.1136/bmj.286.6364.502
   Kennedy P, 2011, J AM GERIATR SOC, V59, P1547, DOI 10.1111/j.1532-5415.2011.03520.x
   Laing R M, 2008, Int J Low Extrem Wounds, V7, P220, DOI 10.1177/1534734608326817
   Laing R, 2009, NEW ZEAL MED J, V122, P114
   Lamyman M J, 2006, J Wound Care, V15, P422
   Llanos S, 2006, ANN SURG, V244, P700, DOI 10.1097/01.sla.0000217745.56657.e5
   Lo S, 2012, J PLAST RECONSTR AES, V65, P1143, DOI 10.1016/j.bjps.2011.12.036
   Moher D, 2009, BMJ-BRIT MED J, V339, DOI 10.1136/bmj.b2535
   Nanchahal J., 2009, Standards for the Management of Open Fractures of the Lower Limb
   Orgill DP, 2011, PLAST RECONSTR SURG, V127, p105S, DOI 10.1097/PRS.0b013e318200a427
   Payne R L, 1990, Ostomy Wound Manage, V26, P26
   RAMNANI SR, 1981, INJURY, V12, P360, DOI 10.1016/0020-1383(81)90003-6
   Rees LS, 2008, INJURY, V39, P781, DOI 10.1016/j.injury.2007.08.025
   SHANKAR S, 1987, ARCH EMERG MED, V4, P187
   SHARPE DT, 1983, BRIT J PLAST SURG, V36, P105, DOI 10.1016/0007-1226(83)90024-3
   SHUSTER S, 1975, BRIT J DERMATOL, V93, P639, DOI 10.1111/j.1365-2133.1975.tb05113.x
   Silk J, 2001, INJURY, V32, P373, DOI 10.1016/S0020-1383(01)00006-7
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   SUTTON R, 1985, BMJ-BRIT MED J, V290, P1627, DOI 10.1136/bmj.290.6482.1627
   Tandon S N, 1973, Br J Plast Surg, V26, P172, DOI 10.1016/S0007-1226(73)80013-X
   Thomson WL, 2014, INJURY, V45, P250, DOI 10.1016/j.injury.2012.07.007
   WOOD SH, 1994, BRIT J PLAST SURG, V47, P127, DOI 10.1016/0007-1226(94)90172-4
   Yan HD, 2013, J TRAUMA ACUTE CARE, V74, P604, DOI 10.1097/TA.0b013e31827d5e00
NR 41
TC 17
Z9 22
U1 0
U2 2
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD DEC
PY 2014
VL 67
IS 12
BP 1694
EP 1702
DI 10.1016/j.bjps.2014.08.001
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AW8ZB
UT WOS:000346546600013
PM 25175272
DA 2026-07-24
ER

PT J
AU Braun, LR
   Fisk, WA
   Lev-Tov, H
   Kirsner, RS
   Isseroff, RR
AF Braun, Liza R.
   Fisk, Whitney A.
   Lev-Tov, Hadar
   Kirsner, Robert S.
   Isseroff, Roslyn R.
TI Diabetic Foot Ulcer: An Evidence-Based Treatment Update
SO AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
LA English
DT Review
ID HYPERBARIC-OXYGEN THERAPY; PRESSURE WOUND THERAPY; OFF-LOADING DEVICES;
   RISK-FACTORS; MANAGEMENT; AMPUTATION; INTERVENTIONS; PREVENTION; HEAL;
   SKIN
AB Background Diabetic foot ulcers (DFUs) are extremely debilitating and difficult to treat. Multidisciplinary management, patient education, glucose control, debridement, offloading, infection control, and adequate perfusion are the mainstays of standard care endorsed by most practice guidelines. Adjunctive therapies represent new treatment modalities endorsed in recent years, though many lack significant high-powered studies to support their use as standard of care.
   Objective This update intends to identify recent, exclusively high level, evidence-based evaluations of DFU therapies. Furthermore, it suggests a direction for future research.
   Methods PubMed, Embase, Ovid Technologies, CI-NAHL, Cochrane, and Web of Science databases were systematically searched for recent systematic reviews published after 2004, and randomized controlled trials published in 2012-2013 that evaluated treatment modalities for DFUs. These papers are reviewed and the quality of available evidence is discussed.
   Results A total of 34 studies met inclusion criteria. Studied therapies include debridement, off-loading, negative pressure therapy, dressings, topical therapies, hyperbaric oxygen therapy, growth factors, bioengineered skin substitutes, electrophysical therapy, and alternative therapy. Good-quality evidence is lacking to justify the use of many of these therapies, with the exception of standard care (offloading, debridement) and possibly negative pressure wound therapy.
   Limitations There is an overall lack of high-level evidence in new adjunctive management of DFU. Comparison of different treatment modalities is difficult, since existing studies are not standardized.
   Conclusions Many therapeutic modalities are available to treat DFU. Quality high-level evidence exists for standard care such as off-loading. Evidence for adjunctive therapies such as negative pressure wound therapy, skin substitutes, and platelet-derived growth factor can help guide adjunctive care but limitations exist in terms of evidence quality.
C1 [Braun, Liza R.; Kirsner, Robert S.] Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA.
   [Fisk, Whitney A.; Isseroff, Roslyn R.] Univ Calif Davis, Dept Dermatol, Sacramento, CA 95817 USA.
   [Lev-Tov, Hadar] Montefiore Med Ctr, Albert Einstein Coll Med, Div Dermatol, Bronx, NY 10467 USA.
   [Isseroff, Roslyn R.] VA Northern Calif Hlth Care Syst, Mather, CA USA.
C3 University of Miami; University of California System; University of
   California Davis; Montefiore Medical Center; Albert Einstein College of
   Medicine; Yeshiva University
RP Lev-Tov, H (通讯作者)，Montefiore Med Ctr, Albert Einstein Coll Med, Div Dermatol, Bronx, NY 10467 USA.
EM lhadar1@gmail.com
RI Isseroff, Roslyn/HPH-5753-2023
FU Organogenesis; Shire; KCI
FX No sources of funding were used to prepare this review. Robert Kirsner
   has received consulting fees or honorarium from Organogenesis, Shire,
   and KCI. Dr. Isseroff, Dr. Lev Tov, Ms. Braun, and Ms. Fisk have no
   conflicts of interest that are directly relevant to the content of this
   review.
CR Abbott CA, 2002, DIABETIC MED, V19, P377, DOI 10.1046/j.1464-5491.2002.00698.x
   Abbott CA, 2010, DIABETES CARE, V33, P1325, DOI 10.2337/dc09-2067
   Alavi A, 2014, J AM ACAD DERMATOL, V70, DOI 10.1016/j.jaad.2013.07.048
   Alavi A, 2014, J AM ACAD DERMATOL, V70, DOI 10.1016/j.jaad.2013.06.055
   Apelqvist J, 2008, DIABETES-METAB RES, V24, pS181, DOI 10.1002/dmrr.848
   Armstrong DG, 2003, DIABETES CARE, V26, P2595, DOI 10.2337/diacare.26.9.2595
   Balingit PP, 2012, WOUND REPAIR REGEN, V20, P482, DOI 10.1111/j.1524-475X.2012.00804.x
   Barber C, 2008, J Wound Care, V17, P517
   Begg C, 1996, JAMA-J AM MED ASSOC, V276, P637, DOI 10.1001/jama.276.8.637
   Blozik E, 2008, DIABETES CARE, V31, P693, DOI 10.2337/dc07-2081
   Boulton AJM, 2004, NEW ENGL J MED, V351, P48, DOI 10.1056/NEJMcp032966
   Boulton AJM, 2008, DIABETES CARE, V31, P1679, DOI 10.2337/dc08-9021
   Brownrigg JRW, 2013, EUR J VASC ENDOVASC, V45, P673, DOI 10.1016/j.ejvs.2013.02.014
   Buchberger B, 2011, EXP CLIN ENDOCR DIAB, V119, P472, DOI 10.1055/s-0031-1279713
   Bus SA, 2008, DIABETES-METAB RES, V24, pS162, DOI 10.1002/dmrr.850
   Chen M, 2010, J ALTERN COMPLEM MED, V16, P889, DOI 10.1089/acm.2009.0470
   Dumville JC, 2012, DIABETOLOGIA, V55, P1902, DOI 10.1007/s00125-012-2558-5
   Dumville JC, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009101.pub3
   Dumville JC, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009111.pub3
   Dumville JC, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009110.pub3
   Dumville JC, 2011, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009099.pub3, 10.1002/14651858.CD009101.pub2]
   Edwards JS, 2010, KNOWL MAN RES PRACT, V8, P1, DOI 10.1057/kmrp.2009.39
   Game FL, 2012, DIABETES-METAB RES, V28, P119, DOI 10.1002/dmrr.2246
   Goldman RJ, 2009, PM&R, V1, P471, DOI 10.1016/j.pmrj.2009.03.012
   Gregg EW, 2007, DIABETES RES CLIN PR, V77, P485, DOI 10.1016/j.diabres.2007.01.005
   Hinchliffe RJ, 2008, DIABETES-METAB RES, V24, pS119, DOI 10.1002/dmrr.825
   Holmes C, 2013, DIABET METAB SYND OB, V6, P17, DOI 10.2147/DMSO.S36024
   Jan W. A., 2012, Journal of Postgraduate Medical Institute, V26, P402
   Jeffcoate WJ, 2009, HEALTH TECHNOL ASSES, V13, P1, DOI 10.3310/hta13540
   Martinez-Zapata MJ, 2012, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD006899.pub2, 10.1002/14651858.CD006899.pub3]
   Katz IA, 2005, DIABETES CARE, V28, P555, DOI 10.2337/diacare.28.3.555
   Knowles EA, 1996, DIABETIC MED, V13, P1064, DOI 10.1002/(SICI)1096-9136(199612)13:12<1064::AID-DIA253>3.3.CO;2-R
   Kranke P, 2012, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD004123.pub3, 10.1002/14651858.CD004123.pub4]
   Kwan RLC, 2013, INT WOUND J, V10, P121, DOI 10.1111/j.1742-481X.2012.01085.x
   Lamont P, 2013, INT J LOW EXTR WOUND, V12, P71, DOI 10.1177/1534734613476519
   Lavery LA, 2010, DIABETES CARE, V33, P1460, DOI 10.2337/dc10-0310
   Lebrun E, 2010, WOUND REPAIR REGEN, V18, P433, DOI 10.1111/j.1524-475X.2010.00619.x
   Lev-Tov H, 2013, TRIALS, V14, DOI 10.1186/1745-6215-14-8
   Lewis J, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD002302.pub2
   Liu R, 2013, MAYO CLIN PROC, V88, P166, DOI 10.1016/j.mayocp.2012.10.021
   Londahl M, 2013, INT WOUND J
   Löndahl M, 2011, CURR DIABETES REP, V11, P285, DOI 10.1007/s11892-011-0194-y
   Malay D Scot, 2006, J Foot Ankle Surg, V45, P366, DOI 10.1053/j.jfas.2006.08.002
   Margolis DJ, 2013, DIABETES CARE, V36, P1961, DOI 10.2337/dc12-2160
   Medical Advisory Secretariat, 2005, Ont Health Technol Assess Ser, V5, P1
   Medical Advisory Secretariat, 2010, Ont Health Technol Assess Ser, V10, P1
   Moher D, 2009, BMJ-BRIT MED J, V339, DOI 10.1136/bmj.b2535
   Morona JK, 2013, DIABETES-METAB RES, V29, P183, DOI 10.1002/dmrr.2386
   Noble-Bell G, 2008, INT WOUND J, V5, P233, DOI 10.1111/j.1742-481X.2008.00430.x
   PECORARO RE, 1990, DIABETES CARE, V13, P513, DOI 10.2337/diacare.13.5.513
   PECORARO RE, 1991, DIABETES, V40, P1305, DOI 10.2337/diabetes.40.10.1305
   Qaseem A, 2010, ANN INTERN MED, V153, P194, DOI 10.7326/0003-4819-153-3-201008030-00010
   Ramsey SD, 1999, DIABETES CARE, V22, P382, DOI 10.2337/diacare.22.3.382
   Reiber G., 2008, Levin and O'Neal's The Diabetic Foot, V7th, P3
   Reiber G.E., 2002, the evidence basis for diabetes care, P641, DOI [10.1002/0470846585.ch28, DOI 10.1002/0470846585.CH28]
   Reiber GE, 1996, DIABETIC MED, V13, pS6, DOI 10.1002/dme.1996.13.s1.6
   Reiber GE, 1999, DIABETES CARE, V22, P157, DOI 10.2337/diacare.22.1.157
   REIBER GE, 1992, ANN INTERN MED, V117, P97, DOI 10.7326/0003-4819-117-2-97
   RITHNAJARIAN SJ, 1992, DIABETES CARE, V15, P1386, DOI 10.2337/diacare.15.10.1386
   Roeckl-Wiedmann I, 2005, BJS-BRIT J SURG, V92, P24, DOI 10.1002/bjs.4863
   Shaw J, 2007, BRIT J DERMATOL, V157, P997, DOI 10.1111/j.1365-2133.2007.08160.x
   Teng YJ, 2010, DIABETES OBES METAB, V12, P307, DOI 10.1111/j.1463-1326.2009.01164.x
   Thakral G, 2013, DIABET FOOT ANKLE, V4, DOI 10.3402/dfa.v4i0.22081
   Vig S, 2011, J TISSUE VIABILITY, V20, pS1, DOI 10.1016/j.jtv.2011.07.002
   Villela DL, 2010, GROWTH FACTORS, V28, P111, DOI 10.3109/08977190903468185
   Voigt J, 2012, WOUND REPAIR REGEN, V20, P317, DOI 10.1111/j.1524-475X.2012.00777.x
   Wilcox JR, 2013, JAMA DERMATOL, V149, P1050, DOI 10.1001/jamadermatol.2013.4960
   Wu SC, 2008, DIABETES CARE, V31, P2118, DOI 10.2337/dc08-0771
   You HJ, 2012, WOUND REPAIR REGEN, V20, P491, DOI 10.1111/j.1524-475X.2012.00809.x
NR 69
TC 86
Z9 108
U1 0
U2 51
PU ADIS INT LTD
PI NORTHCOTE
PA 5 THE WAREHOUSE WAY, NORTHCOTE 0627, AUCKLAND, NEW ZEALAND
SN 1175-0561
EI 1179-1888
J9 AM J CLIN DERMATOL
JI Am. J. Clin. Dermatol.
PD JUL
PY 2014
VL 15
IS 3
BP 267
EP 281
DI 10.1007/s40257-014-0081-9
PG 15
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA AT0BH
UT WOS:000344601300009
PM 24902659
DA 2026-07-24
ER

PT J
AU Labler, L
   Mica, L
   Härter, L
   Trentz, O
   Keel, M
AF Labler, L
   Mica, L
   Härter, L
   Trentz, O
   Keel, M
TI Influence of VAC®-therapy on cyotokines and growth factors in traumatic
   wounds
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nurnberg, GERMANY
DE vacuum assisted closure; VAC (R); trauma; IL-6, IL-8; VEGF; soft tissue
   injury
ID VACUUM-ASSISTED CLOSURE; CARDIAC MYOCYTES; CHEMOKINES; TISSUE;
   EXPRESSION; OXYGEN; VEGF; INTERLEUKIN-10; ANGIOGENESIS; MACROPHAGES
AB Objective: Clinical observations have shown an accelerated woundhealing in wounds of patients treated by Vacuum Assisted Closure (V.A.C.(R))-therapy. The mechanisms of improved wound healing on cellulary level have been hitherto less investigated. In this study the levels of proinflammatory interleukins (IL-6, IL-8, IL-10) and growth factors (VEGF, FGF-2) in serum and wound were monitored. Methods: The study included 21 patients with traumatic wounds that could not be closed during the first surgical intervention. The soft tissue defects (n = 21) were closed temporarily by Epigard(R). During the first second-look operation after 2.0 +/- 0.2 days in an average, Epigard(R) was used for another 2.5 +/- 0.4 days as temporary soft tissue coverage in 13 patients (group A). In the remaining 8 patients the wound conditioning was done by V.A.C.(R) for 2.4 +/- 0.3 days (group B). A total of 428 samples of serum and wound fluid samples were collected during the first and second look operation. Levels of IL-6, IL-8, IL-10, VEGF and FGF were measured specific by ELISA. Results: In all interleukins and growth factors there were significant lower serum level concentrations compared with those in wound fluids. During the first temporary dressing change after wound coverage with Epigard(R) the wound samples showed the following levels [Mean (SEM)]: IL-6 49816 (19889) pg/ml, IL-8 54 (16) ng/ml, IL-10 314 (44) pg/ml, VEGF 4746 (766) pg/ml, FGF-2 494 (89) pg/ml. During the second dressing changes we monitored the following levels in group A: IL-6 7 218 (2 542) pg/ml, IL-8 69 (27) ng/ml, IL-10 261 (58) pg/ml, VEGF 3 551 (661) pg/ml, FGF-2 355 (67) pg/ml. In group B the samples of the wound fluid showed the following results: IL-6 16966 (4124) pg/ml [p=0.02], IL-8 223 (91) ng/ml [p=0.03], IL-10 233 (76) pg/ml [p = 0.38], VEGF 7490 (1565) pg/ml [p = 0.01], FGF-2 352 (43) pg/ml [p = 0.48]. Conclusion: The increased local release of IL-6, IL-8 and VEGF in wounds after V.A.C.(R)-therapy may be involved in the accumulation of neutrophil granulocytes and angiogenesis, which seams to play a crucial role for the accelerated granulation tissue formation after V.A.C.(R)-therapy compared to wounds treated by Epigard(R).
C1 Univ Zurich Hosp, Dept Chirurg, Unfallchirurg Klin, CH-8091 Zurich, Switzerland.
C3 University of Zurich; University Zurich Hospital
RP Labler, L (通讯作者)，Univ Zurich Hosp, Dept Chirurg, Unfallchirurg Klin, Ramistr 100, CH-8091 Zurich, Switzerland.
EM ludwig.labler@usz.ch
CR Ancelin M, 2004, LAB INVEST, V84, P502, DOI 10.1038/labinvest.3700053
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Baggiolini M, 1998, NATURE, V392, P565, DOI 10.1038/33340
   BARBUL A, 1989, ANN SURG, V209, P479, DOI 10.1097/00000658-198904000-00015
   Barton BE, 1997, CLIN IMMUNOL IMMUNOP, V85, P16, DOI 10.1006/clin.1997.4420
   Bonomo SR, 1998, UNDERSEA HYPERBAR M, V25, P211
   Brauchle M, 1996, J BIOL CHEM, V271, P21793, DOI 10.1074/jbc.271.36.21793
   CASSATELLA MA, 1993, J EXP MED, V178, P2207, DOI 10.1084/jem.178.6.2207
   Chodobski A, 2003, NEUROSCIENCE, V122, P853, DOI 10.1016/j.neuroscience.2003.08.055
   Corral CJ, 1999, ARCH SURG-CHICAGO, V134, P200, DOI 10.1001/archsurg.134.2.200
   Darrington RS, 1997, BIOCHEM SOC T, V25, pS292, DOI 10.1042/bst025292s
   DEATON PR, 1994, AM J PHYSIOL, V267, pL187, DOI 10.1152/ajplung.1994.267.2.L187
   DiPietro LA, 1998, J CLIN INVEST, V101, P1693, DOI 10.1172/JCI1020
   DVORAK HF, 1995, AM J PATHOL, V146, P1029
   Engelhardt E, 1998, AM J PATHOL, V153, P1849, DOI 10.1016/S0002-9440(10)65699-4
   FENG JH, 1998, AM J SURG PATHOL, V3, P1
   Ferrara N, 2003, NAT MED, V9, P669, DOI 10.1038/nm0603-669
   FERRARA N, 1993, TRENDS CARDIOVAS MED, V3, P244, DOI 10.1016/1050-1738(93)90046-9
   FIORENTINO DF, 1991, J IMMUNOL, V147, P3815
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Gibson Jeffrey J., 1997, Surgical Forum, V48, P696
   GORMAN PW, 1989, CLIN ORTHOPAEDICS, V243, P57
   Holzheimer R G, 2000, Eur J Med Res, V5, P347
   HUNT TK, 1972, SURG GYNECOL OBSTETR, V135, P561
   KNIGHTON DR, 1983, SCIENCE, V221, P1283, DOI 10.1126/science.6612342
   Kusumanto Yoka H., 2003, Angiogenesis, V6, P283, DOI 10.1023/B:AGEN.0000029415.62384.ba
   Labler L, 2002, Swiss Surg, V8, P266, DOI 10.1024/1023-9332.8.6.266
   LEIBOVICH SJ, 1975, AM J PATHOL, V78, P71
   Li J, 1997, J CLIN INVEST, V100, P18, DOI 10.1172/JCI119510
   Luster AD, 1998, NEW ENGL J MED, V338, P436, DOI 10.1056/NEJM199802123380706
   Malefyt R.de Waal., 1991, J EXP MED, V174, P1209
   MARX RE, 1990, AM J SURG, V160, P519, DOI 10.1016/S0002-9610(05)81019-0
   MOORE KW, 1993, ANNU REV IMMUNOL, V11, P165, DOI 10.1146/annurev.iy.11.040193.001121
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mukaida N, 1998, CYTOKINE GROWTH F R, V9, P9, DOI 10.1016/S1359-6101(97)00022-1
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Nissen NN, 1998, AM J PATHOL, V152, P1445
   OLENIUS M, 1993, PLAST RECONSTR SURG, V91, P213, DOI 10.1097/00006534-199302000-00001
   Pufe T, 2004, AM J PATHOL, V164, P185, DOI 10.1016/S0002-9440(10)63109-4
   Quinn TP, 2002, AM J PHYSIOL-LUNG C, V282, pL897, DOI 10.1152/ajplung.00044.2001
   Rossi D, 2000, ANNU REV IMMUNOL, V18, P217, DOI 10.1146/annurev.immunol.18.1.217
   SADOSHIMA J, 1993, EMBO J, V12, P1681, DOI 10.1002/j.1460-2075.1993.tb05813.x
   Sato Y, 1999, BIOCHEM BIOPH RES CO, V265, P194, DOI 10.1006/bbrc.1999.1455
   Seko Y, 1999, BIOCHEM BIOPH RES CO, V254, P462, DOI 10.1006/bbrc.1998.9969
   Sheikh AY, 2000, ARCH SURG-CHICAGO, V135, P1293, DOI 10.1001/archsurg.135.11.1293
   Skutek M, 2001, KNEE SURG SPORT TR A, V9, P322
   SUMPIO BE, 1988, J SURG RES, V44, P696, DOI 10.1016/0022-4804(88)90103-5
   Trengove NJ, 2000, WOUND REPAIR REGEN, V8, P13, DOI 10.1046/j.1524-475x.2000.00013.x
   Werner S, 2003, PHYSIOL REV, V83, P835, DOI 10.1152/physrev.2003.83.3.835
   Xiong M, 1998, AM J PATHOL, V153, P587, DOI 10.1016/S0002-9440(10)65601-5
NR 50
TC 28
Z9 34
U1 0
U2 3
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S62
EP S67
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 034DB
UT WOS:000236904100014
PM 16575647
DA 2026-07-24
ER

PT J
AU Zhou, M
   Yu, AX
   Wu, G
   Xia, CY
   Hu, X
   Qi, BW
AF Zhou, Min
   Yu, Aixi
   Wu, Gang
   Xia, Chengyan
   Hu, Xiang
   Qi, Baiwen
TI Role of different negative pressure values in the process of infected
   wounds treated by vacuum-assisted closure: an experimental study
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Different negative pressure values; VAC; Vacuum-assisted closure; Wound
   healing
ID ENDOTHELIAL GROWTH-FACTOR; SUBATMOSPHERIC PRESSURE; THERAPY; EXPERIENCE;
   FREQUENCY; OUTCOMES; TRIAL
AB Vacuum-assisted closure (VAC) device is widely used to treat infected wounds in clinical work. Although the effect of VAC with different negative pressure values is well established, whether different negative pressures could result in varying modulation of wound relative cytokines was not clear. We hypothesise that instead of the highest negative pressure value the suitable value for VAC is the one which is the most effective on regulating wound relative cytokines. Infected wounds created on pigs' back were used to investigate the effects of varying negative pressure values of VAC devices. Wounds were treated with VAC of different negative pressure values or moist gauze, which was set as control. The VAC foam, semiocclusive dresses and moist gauze were changed on days 3, 5, 7 and 9 after wounds were created. When changing dressings, tissues from wounds were harvested for bacteria count and histology examination including Masson's trichrome stain and immunohistochemistry for microvessels. Western blot was carried out to test the expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF). Results showed that on days 3 and 5 the number of bacteria in wounds treated by VAC with 75, 150, 225 and 300 mmHg was significantly decreased compared with that in wounds treated by gauze and 0 mmHg pressure value. However, there was no difference in wounds treated with negative pressure values of 75 , 150, 225 and 300 mmHg at any time spot. Immunohistochemistry showed that more microvessels were generated in wounds treated by VAC using 75 and 150 mmHg negative pressure comparing with that using 225 and 300 mmHg on days 3 and 5. However this difference vanished on days 7 and 9. Morphological evaluation by Masson's trichrome staining showed increased collagen deposition in VAC of 75 and 150 mmHg compared with that in VAC of 225 and 300 mmHg. Western blot showed that the expression of VEGF and bFGF significantly increased when the wounds treated with 75 and 150 mmHg negative pressure values compared with the wounds treated with 225 and 300 mmHg on day 5. Treatment using VAC with different negative pressure values more than 75 mmHg has similar efficiency on reducing bacteria in the infected wound. VAC with negative pressure values of 75 and 150 mmHg promote wound healing more quickly than other pressure values. Moreover, comparing with vigorous negative pressure, relatively moderate pressures contribute to wound healing via accelerated granulation growth, increased angiogenic factor production and improved collagen fibre deposition. Further study of this model may show other molecular mechanisms.
C1 [Zhou, Min; Yu, Aixi; Wu, Gang; Xia, Chengyan; Hu, Xiang; Qi, Baiwen] Wuhan Univ, Zhongnan Hosp, Dept Microorthoped, Wuhan 430071, Peoples R China.
C3 Wuhan University
RP Yu, AX (通讯作者)，Wuhan Univ, Zhongnan Hosp, Dept Microorthoped, 169 Donghu Rd, Wuhan 430071, Peoples R China.
EM yuaixi666@163.com
OI Yu, Aixi/0000-0002-3751-0894
FU National Natural Science Funds of China [81171713]
FX The authors would like to thank Chen Wei-ming for his instruction on
   this trial, and thank VSD company (Wuhan, China) for supplying vacuum
   pump, open-pore foam and semiocclusive dressing. This study was financed
   by the National Natural Science Funds of China. Project code: 81171713.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Assadian O, 2010, INT WOUND J, V7, P283, DOI 10.1111/j.1742-481X.2010.00686.x
   Baharestani MM, 2011, INT WOUND J, V8, P118, DOI 10.1111/j.1742-481X.2010.00756.x
   Bao P, 2009, J SURG RES, V153, P347, DOI 10.1016/j.jss.2008.04.023
   Boone D, 2010, WOUNDS, V22, P32
   Borgquist O, 2010, OSTOMY WOUND MANAG, V56, P60
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Derrick KL, 2008, INT WOUND J, V5, P615, DOI 10.1111/j.1742-481X.2008.00544.x
   Fabian TS, 2000, AM SURGEON, V66, P1136
   Gabriel A, 2009, INT WOUND J, V6, P1, DOI 10.1111/j.1742-481X.2009.00628.x
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   Hsu CC, 2010, AM J PHYSIOL-CELL PH, V299, pC528, DOI 10.1152/ajpcell.00504.2009
   Ichioka S, 2008, WOUND REPAIR REGEN, V16, P460, DOI 10.1111/j.1524-475X.2008.00390.x
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P263
   Jacobs S, 2009, J PLAST RECONSTR AES, V62, P1331, DOI 10.1016/j.bjps.2008.03.024
   Joseph E, 2000, WOUNDS, V12, P60
   Kondo T, 2010, FORENSIC SCI INT, V203, P93, DOI 10.1016/j.forsciint.2010.07.004
   Labler L, 2009, J TRAUMA, V66, P749, DOI 10.1097/TA.0b013e318171971a
   MCLEOD KJ, 1987, SCIENCE, V236, P1465, DOI 10.1126/science.3589667
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Mouës CM, 2011, AM J SURG, V201, P544, DOI 10.1016/j.amjsurg.2010.04.029
   Nauta A, 2011, ORAL DIS, V17, P541, DOI 10.1111/j.1601-0825.2011.01787.x
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Quinn TP, 2002, AM J PHYSIOL-LUNG C, V282, pL897, DOI 10.1152/ajplung.00044.2001
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Shi Bing, 2003, Zhonghua Zheng Xing Wai Ke Za Zhi, V19, P279
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   Valls MD, 2009, BIOCHEM PHARMACOL, V77, P1117, DOI 10.1016/j.bcp.2008.11.002
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Werner S, 2003, PHYSIOL REV, V83, P835, DOI 10.1152/physrev.2003.83.3.835
   Wilkes R, 2009, J BIOMECH ENG-T ASME, V131, DOI 10.1115/1.2947358
NR 33
TC 36
Z9 44
U1 0
U2 29
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD OCT
PY 2013
VL 10
IS 5
BP 508
EP 515
DI 10.1111/j.1742-481X.2012.01008.x
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 227DW
UT WOS:000325090300006
PM 22640026
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Rajabaleyan, P
   Kaalby, L
   Deding, U
   al-Najami, I
   Ellebæk, MB
AF Rajabaleyan, Pooya
   Kaalby, Lasse
   Deding, Ulrik
   al-Najami, Issam
   Ellebaek, Mark Bremholm
TI Mortality in patients with secondary peritonitis treated by primary
   closure or vacuum-assisted closure: nationwide register-based cohort
   study
SO BJS OPEN
LA English
DT Article
DE open abdomen; primary abdominal closure
ID TEMPORARY ABDOMINAL CLOSURE; EMERGENCY GENERAL-SURGERY; PRESSURE WOUND
   THERAPY; OPEN ABDOMEN TREATMENT; PLANNED RELAPAROTOMY; INTRAABDOMINAL
   INFECTIONS; SEPTIC PATIENTS; ON-DEMAND; SEPSIS; WSES
AB Background Secondary peritonitis caused by gastrointestinal perforation is associated with significant morbidity and mortality. Effective management includes surgical source control, antibiotic therapy, and intensive resuscitation. The choice between primary abdominal closure (PAC) and vacuum-assisted closure (VAC) in the management of secondary peritonitis remains a subject of debate.Methods This Danish nationwide register-based cohort study included patients undergoing emergency surgery for secondary peritonitis from perforation of the small intestine, colon, or rectum between 2007 and 2021 who were treated with either PAC or VAC. Data were extracted from national registries, including the Danish Register of Cause of Death and the Danish National Patient Registry. The primary outcome was overall all-cause mortality; secondary outcomes were all-cause mortality at 30 days, 90 days, and 1 year.Results In all, 13 898 patients were included (1017 in the VAC group, 12 881 in the PAC group). VAC-treated patients had significantly higher Charlson Co-morbidity Index scores and were slightly younger. In the subgroup with available laboratory data, VAC-treated patients also presented with more severe biochemical derangements, including elevated C-reactive protein, leukocytes, bilirubin, and lactate, as well as lower haemoglobin, suggesting a higher baseline severity of illness. The overall risk-stratified mortality rate (RSMR) was 49.1% for VAC and 52.0% for PAC (P = 0.222). The 30-day mortality rate was 16.9% in both the VAC and PAC groups, with RSMR of 17.4% and 18.3%, respectively (P = 0.656). At 90 days, mortality was 24.3% and 22.5% in the VAC and PAC groups, respectively, with a corresponding RSMR of 23.2% and 24.2% (P = 0.437). One year after surgery, the mortality rate was 31.3% for VAC and 29.5% for PAC, with a corresponding RSMR of 30.3% and 31.6% (P = 0.346).Conclusion This nationwide cohort study revealed no significant differences in mortality between PAC and VAC in patients with secondary peritonitis at any of the designated time points. Demographic and laboratory data suggest that VAC-treated patients had a higher baseline severity of illness.
   This nationwide Danish register-based cohort study compared mortality outcomes in 13 898 patients undergoing surgery for secondary peritonitis between primary abdominal closure (PAC) and vacuum-assisted closure (VAC). No significant differences were found in overall or time-specific (30-day, 90-day, and 1-year) mortality between the two groups. These findings suggest that PAC and VAC are comparable in terms of mortality outcomes in the management of secondary peritonitis.
C1 [Rajabaleyan, Pooya; Kaalby, Lasse; Deding, Ulrik; al-Najami, Issam; Ellebaek, Mark Bremholm] Odense Univ Hosp, Res Unit Surg, JB Winslows Vej 4, DK-5000 Odense, Denmark.
   [Rajabaleyan, Pooya; Kaalby, Lasse; Deding, Ulrik; al-Najami, Issam; Ellebaek, Mark Bremholm] Univ Southern Denmark, Fac Hlth Sci, Odense, Denmark.
C3 University of Southern Denmark; Odense University Hospital; University
   of Southern Denmark
RP Rajabaleyan, P (通讯作者)，Odense Univ Hosp, Res Unit Surg, JB Winslows Vej 4, DK-5000 Odense, Denmark.
EM Pooya.Rajabaleyan@skane.se
RI Kaalby, Lasse/AGN-4657-2022; Deding, Ulrik/AAE-2844-2019; Ellebaek, Mark
   Bremholm/ADW-1803-2022
OI Kaalby, Lasse/0000-0002-6721-3604; Rajabaleyan,
   Pooya/0000-0002-6882-9427; Deding, Ulrik/0000-0002-8263-2989; Ellebaek,
   Mark Bremholm/0000-0001-6550-7505
CR Arvaniti K, 2022, INT J ANTIMICROB AG, V60, DOI 10.1016/j.ijantimicag.2022.106591
   Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
   Baadsgaard M, 2011, SCAND J PUBLIC HEALT, V39, P103, DOI 10.1177/1403494811405098
   Bader FG, 2009, EUR J MED RES, V14, P491, DOI 10.1186/2047-783X-14-11-491
   Bensignor T, 2018, WORLD J SURG, V42, P3589, DOI 10.1007/s00268-018-4687-6
   Berg A, 2022, LANGENBECK ARCH SURG, V407, P259, DOI 10.1007/s00423-021-02304-8
   Bertelsen CA, 2014, WORLD J SURG, V38, P774, DOI 10.1007/s00268-013-2360-7
   Bleszynski MS, 2016, AM J SURG, V211, P926, DOI 10.1016/j.amjsurg.2016.01.012
   Blot S, 2019, INTENS CARE MED, V45, P1703, DOI 10.1007/s00134-019-05819-3
   Coccolini F, 2024, J TRAUMA ACUTE CARE, V96, pe39, DOI 10.1097/TA.0000000000004253
   Coccolini F, 2023, WORLD J EMERG SURG, V18, DOI 10.1186/s13017-023-00509-4
   Coccolini F, 2019, INJURY, V50, P160, DOI 10.1016/j.injury.2018.09.040
   Coccolini F, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0167-4
   Coccolini F, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0146-1
   De Pascale G, 2022, INTENS CARE MED, V48, P1593, DOI 10.1007/s00134-022-06883-y
   Emr B, 2014, SHOCK, V41, P317, DOI 10.1097/SHK.0000000000000121
   Fortelny RH, 2014, SURG ENDOSC, V28, P735, DOI 10.1007/s00464-013-3251-6
   Gasser E, 2021, FRONT SURG, V8, DOI 10.3389/fsurg.2021.632929
   Helweg-Larsen K, 2011, SCAND J PUBLIC HEALT, V39, P26, DOI 10.1177/1403494811399958
   Horwood J, 2009, ANN ROY COLL SURG, V91, P681, DOI 10.1308/003588409X12486167520993
   Huston JM, 2024, SURG INFECT, V25, P419, DOI 10.1089/sur.2024.137
   Hutchins RR, 2004, WORLD J SURG, V28, P137, DOI 10.1007/s00268-003-7067-8
   Jannasch O, 2018, POL J SURG, V90, P27, DOI 10.5604/01.3001.0012.1751
   Jensen VM, 2011, SCAND J PUBLIC HEALT, V39, P91, DOI 10.1177/1403494810394715
   Kafka-Ritsch R, 2020, WORLD J SURG, V44, P4098, DOI 10.1007/s00268-020-05762-1
   Kafka-Ritsch R, 2012, WORLD J SURG, V36, P1765, DOI 10.1007/s00268-012-1586-0
   Kao AM, 2019, J TRAUMA ACUTE CARE, V87, P623, DOI 10.1097/TA.0000000000002345
   Kirkpatrick AW, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0183-4
   Kirkpatrick AW, 2015, ANN SURG, V262, P38, DOI 10.1097/SLA.0000000000001095
   Kubiak BD, 2010, SHOCK, V34, P525, DOI 10.1097/SHK.0b013e3181e14cd2
   Kunitatsu K, 2023, ANN MED SURG, V85, P645, DOI 10.1097/MS9.0000000000000334
   Lamme B, 2004, BJS-BRIT J SURG, V91, P1046, DOI 10.1002/bjs.4517
   Loftus TJ, 2017, J TRAUMA ACUTE CARE, V82, P345, DOI 10.1097/TA.0000000000001283
   Lynge E, 2011, SCAND J PUBLIC HEALT, V39, P30, DOI 10.1177/1403494811401482
   Marshall John C, 2004, Crit Care Med, V32, pS513, DOI 10.1097/01.CCM.0000143119.41916.5D
   Mintziras I, 2016, LANGENBECK ARCH SURG, V401, P619, DOI 10.1007/s00423-016-1443-y
   Müller V, 2020, ACTA CHIR BELG, V120, P179, DOI 10.1080/00015458.2019.1576448
   Mutafchiyski VM, 2016, J ROY ARMY MED CORPS, V162, P30, DOI 10.1136/jramc-2014-000386
   Olejnik J, 2007, BRATISL MED J, V108, P320
   Pliakos I, 2012, AM SURGEON, V78, P957
   Poillucci G, 2021, EUR J TRAUMA EMERG S, V47, P1819, DOI 10.1007/s00068-020-01379-0
   Poulton TE, 2018, BJS-BRIT J SURG, V105, P959, DOI 10.1002/bjs.10848
   Quan HD, 2011, AM J EPIDEMIOL, V173, P676, DOI 10.1093/aje/kwq433
   Rajabaleyan P, 2025, WORLD J SURG, V49, P387, DOI 10.1002/wjs.12472
   Rajabaleyan P, 2023, BMC SURG, V23, DOI 10.1186/s12893-023-02179-0
   Rajabaleyan P, 2022, WORLD J EMERG SURG, V17, DOI 10.1186/s13017-022-00427-x
   Rakic M, 2005, CROAT MED J, V46, P957
   Reitz KM, 2022, JAMA SURG, V157, P817, DOI 10.1001/jamasurg.2022.2761
   Richter S, 2013, GASTROENT RES PRACT, V2013, DOI 10.1155/2013/730829
   Robledo Felipe A, 2007, Surg Infect (Larchmt), V8, P63, DOI 10.1089/sur.2006.8.016
   Rosenzweig M, 2020, SURG INFECT, V21, P665, DOI 10.1089/sur.2019.272
   Ross JT, 2018, BMJ-BRIT MED J, V361, DOI 10.1136/bmj.k1407
   Sakr Y, 2018, OPEN FORUM INFECT DI, V5, DOI 10.1093/ofid/ofy313
   Sartelli M, 2024, WORLD J EMERG SURG, V19, DOI 10.1186/s13017-024-00552-9
   Sartelli M, 2021, WORLD J EMERG SURG, V16, DOI 10.1186/s13017-021-00387-8
   Sartelli M, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0141-6
   Sartelli M, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0132-7
   Sartelli M, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0055-0
   Sartelli M, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0032-7
   Sartelli M, 2014, WORLD J EMERG SURG, V9, DOI 10.1186/1749-7922-9-22
   Schmelzle M, 2010, DIGEST SURG, V27, P272, DOI 10.1159/000314609
   Stewart B, 2014, BRIT J SURG, V101, pE9, DOI 10.1002/bjs.9329
   Tao QS, 2014, GASTROENT RES PRACT, V2014, DOI 10.1155/2014/245182
   Tartaglia D, 2021, UPDATES SURG, V73, P1975, DOI 10.1007/s13304-021-01012-8
   Tolonen M, 2017, J TRAUMA ACUTE CARE, V82, P1100, DOI 10.1097/TA.0000000000001452
   van Ruler O, 2007, JAMA-J AM MED ASSOC, V298, P865, DOI 10.1001/jama.298.8.865
   van Ruler O, 2007, CRIT CARE MED, V35, P468, DOI 10.1097/01.CCM.0000253399.03545.2D
   van Ruler O, 2011, BMC SURG, V11, DOI 10.1186/1471-2482-11-38
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
   Zhang YQ, 2023, J AM COLL SURGEONS, V236, P208, DOI 10.1097/XCS.0000000000000429
NR 70
TC 0
Z9 1
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 2474-9842
J9 BJS OPEN
JI BJS Open
PD DEC
PY 2025
VL 9
IS 6
AR zraf118
DI 10.1093/bjsopen/zraf118
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 9OW4C
UT WOS:001611504500001
PM 41219129
OA Green Published, Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Bristow, PC
   Perry, KL
   Halfacree, ZJ
   Lipscomb, VJ
AF Bristow, Poppy C.
   Perry, Karen L.
   Halfacree, Zoe J.
   Lipscomb, Vicky J.
TI Use of vacuum-assisted closure to maintain viability of a skin flap in a
   dog
SO JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION
LA English
DT Article
ID CAPILLARY BLOOD-FLOW; NEGATIVE-PRESSURE; SUBATMOSPHERIC PRESSURE;
   HYPERBARIC-OXYGEN; WOUND THERAPY; THORACODORSAL; COMPLICATIONS;
   ANALGESIA; EFFICACY; STRESS
AB Case Description-A 4-year-old sexually intact male Labrador Retriever Poodle mix was admitted to the hospital for treatment of a wound in the left thoracic region.The wound had been debrided and primary closure had been performed by the referring veterinarian 4 days previously.
   Clinical Findings-The dog had a 20-cm-long wound covered by a large flap of skin that extended caudally from the scapula over the left side of the thorax. A 3-cm defect was evident at the cranioventral aspect of the wound, from which purulent material was being discharged. The skin flap was necrotic, and the skin surrounding the flap was bruised. Signs of pain were elicited when the wound and surrounding region were palpated. Other findings, including those of thoracic radiography, were unremarkable.
   Treatment and Outcome-The wound was debrided, and vacuum-assisted closure (VAC) was initiated for 3 days until a healthy bed of granulation tissue developed. A reconstructive procedure was performed with a rotation flap 3 days after VAC dressing removal. The VAC process was reinitiated 2 days following reconstruction because of an apparent failing of the skin flap viability. After 5 days of VAC, the flap had markedly improved in color and consistency and VAC was discontinued. Successful healing of the flap occurred without the need for debridement or additional intervention.
   Clinical Relevance-Use of VAC led to a good overall outcome for the dog, with complete healing achieved. Additional evaluation of this technique for salvaging failing skin flaps is warranted in dogs, particularly considering that no reliable method for flap salvage in veterinary species has been reported to date.
C1 [Bristow, Poppy C.; Perry, Karen L.; Halfacree, Zoe J.; Lipscomb, Vicky J.] Univ London Royal Vet Coll, Queen Mother Hosp Anim, Hatfield AL9 7TA, Herts, England.
C3 University of London; University of London Royal Veterinary College
RP Bristow, PC (通讯作者)，Univ London Royal Vet Coll, Queen Mother Hosp Anim, Hatfield AL9 7TA, Herts, England.
EM pbristow@rvc.ac.uk
RI ; Perry, Karen/AAY-7641-2020
OI Bristow, Poppy/0000-0002-6198-8636; Perry, Karen/0000-0001-6456-1817;
   Halfacree, Zoe/0000-0001-6891-8828
CR Akan M, 2005, SCAND J PLAST RECONS, V39, P7, DOI 10.1080/02844310410017951
   Aper R, 2003, VET SURG, V32, P378, DOI 10.1053/jvet.2003.50043
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Banwell P E, 2003, J Wound Care, V12, P22
   Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   BARDACH J, 1978, OTOLARYNG HEAD NECK, V86, P492, DOI 10.1177/019459987808600322
   Ben-Amotz R, 2007, VET SURG, V36, P684, DOI 10.1111/j.1532-950X.2007.00321.x
   Bianconi M, 2003, BRIT J ANAESTH, V91, P830, DOI 10.1093/bja/aeg277
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Davis R E, 1999, Arch Facial Plast Surg, V1, P27, DOI 10.1001/archfaci.1.1.27
   Deva AK, 2000, MED J AUSTRALIA, V173, P128, DOI 10.5694/j.1326-5377.2000.tb125564.x
   EREN S, 1995, PLAST RECONSTR SURG, V96, P1636, DOI 10.1097/00006534-199512000-00018
   Fabian TS, 2000, AM SURGEON, V66, P1136
   Fenn CH, 2001, BRIT J PLAST SURG, V54, P348, DOI 10.1054/bjps.2000.3552
   Fleischmann W, 1995, Eur J Orthop Surg Traumatol, V5, P37, DOI 10.1007/BF02716212
   Friedman HIF, 2006, PLAST RECONSTR SURG, V117, p175S, DOI 10.1097/01.prs.0000222555.84962.86
   Gouttefangeas C, 2001, CLIN EXP IMMUNOL, V124, P398, DOI 10.1046/j.1365-2249.2001.01547.x
   Guille AE, 2007, JAVMA-J AM VET MED A, V230, P1669, DOI 10.2460/javma.230.11.1669
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P263
   Kiessling AH, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-16
   Leach RM, 1998, BMJ-BRIT MED J, V317, P1140
   Liu SS, 2006, J AM COLL SURGEONS, V203, P914, DOI 10.1016/j.jamcollsurg.2006.08.007
   Lucchinetti E, 2012, ANESTHESIOLOGY, V116, P841, DOI 10.1097/ALN.0b013e31824babfe
   Morgan Kenneth, 2006, J Foot Ankle Surg, V45, P417, DOI 10.1053/j.jfas.2006.09.016
   MORRIS T, 1977, BRIT J SURG, V64, P902, DOI 10.1002/bjs.1800641219
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   NAKATSUKA T, 1985, PLAST RECONSTR SURG, V76, P374, DOI 10.1097/00006534-198509000-00006
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   OWEN H, 1985, ANN ROY COLL SURG, V67, P114
   PANG CY, 1984, PLAST RECONSTR SURG, V74, P513, DOI 10.1097/00006534-198410000-00009
   PAVLETIC MM, 1981, AM J VET RES, V42, P391
   Payette JR, 2005, PLAST RECONSTR SURG, V115, P539, DOI 10.1097/01.PRS.0000148415.54546.CA
   Pinocy J, 2003, WOUND REPAIR REGEN, V11, P104, DOI 10.1046/j.1524-475X.2003.11205.x
   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   SKAGEN K, 1983, ACTA PHYSIOL SCAND, V117, P411, DOI 10.1111/j.1748-1716.1983.tb00014.x
   Thompson JT, 2007, CLIN PLAST SURG, V34, P673, DOI 10.1016/j.cps.2007.07.005
   Timmers MS, 2005, ANN PLAS SURG, V55, P665, DOI 10.1097/01.sap.0000187182.90907.3d
   TSAI TM, 1982, PLAST RECONSTR SURG, V70, P444, DOI 10.1097/00006534-198210000-00006
   URSCHEL JD, 1988, BRIT J PLAST SURG, V41, P182, DOI 10.1016/0007-1226(88)90049-5
   Waite A, 2010, BRIT J ANAESTH, V104, P768, DOI 10.1093/bja/aeq093
   Wallis L, 2010, AM J NURS, V110, P16, DOI 10.1097/01.NAJ.0000368938.90936.17
   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
NR 46
TC 14
Z9 16
U1 0
U2 25
PU AMER VETERINARY MEDICAL ASSOC
PI SCHAUMBURG
PA 1931 N MEACHAM RD SUITE 100, SCHAUMBURG, IL 60173-4360 USA
SN 0003-1488
EI 1943-569X
J9 JAVMA-J AM VET MED A
JI JAVMA-J. Am. Vet. Med. Assoc.
PD SEP 15
PY 2013
VL 243
IS 6
BP 863
EP 868
PG 6
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA 255HL
UT WOS:000327229900018
PM 24004235
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Oomen, JWPM
   Spauwen, PHM
   Bleichrodt, RP
   van Goor, H
AF Oomen, J. W. P. M.
   Spauwen, P. H. M.
   Bleichrodt, R. P.
   van Goor, H.
TI Guideline proposal to reconstructive surgery for complex perineal sinus
   or rectal fistula
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Article
DE muscle transposition; perineal sinus; guideline; vacuum assisted closure
ID MODIFIED MARTIUS GRAFT; MYOCUTANEOUS FLAP; CROHNS-DISEASE;
   CLINICAL-EXPERIENCE; ABDOMINIS MUSCLE; CLOSURE; OMENTOPLASTY;
   PROCTECTOMY; RESECTION
AB Aim: To evaluate a guideline approach of reconstructive surgery for complex perineal sinus or rectal fistula. Methods: pre-, per-, and postoperative data of 28 patients undergoing transposition of rectus abdominis muscle (TRAM), gracilis muscle (GM), gluteal thigh flap (GTF), or omentoplasty (OP) for complex perineal sinus or rectal fistula were analyzed. A fistula higher than 10 cm and a sinus with a length of > 10 cm were treated with TRAM or OP. If < 8 cm, the first choice was GM or GTF. The operative team made choice between 8 and 10 cm. Vacuum assisted closure (VAC) therapy was used as adjunct therapy before and after muscle transposition in huge sinus. Success was defined as no residual or recurrent sinus or fistula within 6 months, post-operatively. Long-term complaints of perineum and muscle donor site were assessed. Results: Twenty-five out of 28 patients (90%) were treated according to the guideline. VAC therapy was done in six. Three patients died during mean follow up of 40 months (6-90). Initial success rate was 61% (17/28). After secondary surgery in seven, four (57%) were successful. Overall success rate, including VAC therapy, was 79% (22/28). Success was highest with GM and GTF and in small sinus or fistula. Conclusion: A guideline approach to complex perineal sinus or fistula based on length or height of the sinus or rectal fistula, respectively, is successful in about 80% of cases. Large defects may best be downsized by VAC therapy, followed by muscle flap. Long-term complaints are acceptable.
C1 Radboud Univ Nijmegen, Med Ctr, Dept Reconstruct Surg, NL-6500 HB Nijmegen, Netherlands.
   Radboud Univ Nijmegen, Med Ctr, Dept Gastrointestinal Surg, NL-6500 HB Nijmegen, Netherlands.
C3 Radboud University Nijmegen; Radboud University Nijmegen
RP Oomen, JWPM (通讯作者)，Radboud Univ Nijmegen, Med Ctr, Dept Reconstruct Surg, POB 9101, NL-6500 HB Nijmegen, Netherlands.
EM judithoomen@hotmail.com
RI van+Goor, Harry/AAS-7712-2020
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BROUGH WA, 1991, DIS COLON RECTUM, V34, P148, DOI 10.1007/BF02049989
   ELKINS TE, 1990, OBSTET GYNECOL, V75, P727
   Hay JM, 1997, EUR J SURG, V163, P199
   Hurst RD, 2001, SURGERY, V130, P767, DOI 10.1067/msy.2001.117100
   HURWITZ DJ, 1980, BRIT J PLAST SURG, V33, P256, DOI 10.1016/0007-1226(80)90023-5
   MCCRAW JB, 1976, PLAST RECONSTR SURG, V58, P176, DOI 10.1097/00006534-197608000-00006
   Pemberton John H, 2003, Colorectal Dis, V5, P486, DOI 10.1046/j.1463-1318.2003.00520.x
   Pinedo G, 1998, ANN ROY COLL SURG, V80, P410
   Radice E, 1999, BRIT J SURG, V86, P349, DOI 10.1046/j.1365-2168.1999.01044.x
   Spauwen PHM, 2000, EUR J PLAST SURG, V23, P192, DOI 10.1007/s002380050248
   Tran KTC, 1999, DIS COLON RECTUM, V42, P486, DOI 10.1007/BF02234173
   Tsang CBS, 1997, SURG CLIN N AM, V77, P95, DOI 10.1016/S0039-6109(05)70535-1
   Wu SH, 2000, EUR J PLAST SURG, V23, P174, DOI 10.1007/s002380050243
   Yamamoto T, 1999, DIS COLON RECTUM, V42, P96, DOI 10.1007/BF02235190
   Yamamoto T, 2001, AM J SURG, V181, P265, DOI 10.1016/S0002-9610(01)00561-X
NR 16
TC 18
Z9 22
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0179-1958
EI 1432-1262
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD FEB
PY 2007
VL 22
IS 2
BP 225
EP 230
DI 10.1007/s00384-006-0126-5
PG 6
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 117PE
UT WOS:000242884400016
PM 16552521
DA 2026-07-24
ER

PT J
AU Tewarie, L
   Moza, AK
   Khattab, MA
   Autschbach, R
   Zayat, R
AF Tewarie, Lachmandath
   Moza, Ajay K.
   Khattab, Mohammad Amen
   Autschbach, Ruediger
   Zayat, Rashad
TI Effective Combination of Different Surgical Strategies for Deep Sternal
   Wound Infection and Mediastinitis
SO ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
DE deep sternal wound infection; mediastinitis; bilateral pectoral major
   muscle flap; omental flap
ID VACUUM-ASSISTED CLOSURE; OMENTAL FLAP; RISK-FACTORS; TRANSPOSITION;
   MANAGEMENT; SURGERY; IMPACT
AB Purpose: Timing and ideal reconstructive approach in deep sternal wound infection (DSWI) and mediastinitis still remain controversially debated. We present our own combined surgical strategy of bilateral pectoralis major muscle flap (BPMMF) or omental flap (OF) transposition.
   Methods: Between July 2010 and July 2016, poststernotomy patients with DSWI and mediastinitis underwent a secondary wound closure with modified BPMMF (Group A, center for disease control class (CDC)-II, n = 21; Group B, CDC-III, n = 20) or with OF (Group C, CDC-III, n = 19) following vacuum-assisted closure (VAC).
   Results: Significant risk factors for mediastinitis (CDC-III) were chronic obstructive pulmonary disease (COPD; p = 0.001), peripheral arterial disease (PAD; p = 0.012), cardiopulmonary bypass (CPB) time (p = 0.027), total operation time (p = 0.039), total intensive care unit (ICU) stay (p = 0.011), and blood transfusion (p = 0.049). Mean antibiotic therapy (18.4 +/- 8.8[B] vs. 36.2 +/- 24.4[C] days, p = 0.026) and length of hospitalization (25.2 +/- 12.1[B] vs 53.8 +/- 18.5 days[C], p = 0.053) were significantly longer in group C. In-hospital death was 3/19 (15.8%) in group C versus 0 in group B (p = 0.026). Frequency of recurrent mediastinitis was equal (p = 0.92); however, complications occurred more often in group C (31.6% vs. 0%, p = 0.031). The mean follow-up time was 111 +/- 62 days.
   Conclusion: In younger (< 70 years) patients without sternal bone necrosis, the BPMMF is superior to the OF technique with relatively low recurrence and mortality risks.
C1 [Tewarie, Lachmandath; Moza, Ajay K.; Khattab, Mohammad Amen; Autschbach, Ruediger; Zayat, Rashad] Univ Hosp RWTH Aachen, Dept Thorac & Cardiovasc Surg, Pauwelsstr 30, D-52074 Aachen, Germany.
C3 RWTH Aachen University; RWTH Aachen University Hospital
RP Zayat, R (通讯作者)，Univ Hosp RWTH Aachen, Dept Thorac & Cardiovasc Surg, Pauwelsstr 30, D-52074 Aachen, Germany.
EM rzayat@ukaachen.de
RI Zayat, Rashad/U-5505-2019; Moza, Ajay/KFR-7226-2024
OI Zayat, Rashad/0000-0003-2243-8743; 
CR Athanassiadi Kalliopi, 2007, Asian Cardiovasc Thorac Ann, V15, P200
   Atkins BZ, 2011, AM J SURG, V202, P565, DOI 10.1016/j.amjsurg.2011.06.013
   Berg HF, 2000, ANN THORAC SURG, V70, P924, DOI 10.1016/S0003-4975(00)01524-1
   Borger MA, 1998, ANN THORAC SURG, V65, P1050, DOI 10.1016/S0003-4975(98)00063-0
   Diez C, 2007, J CARDIOTHORAC SURG, V2, DOI 10.1186/1749-8090-2-23
   Douville EC, 2004, ANN THORAC SURG, V78, P1659, DOI 10.1016/j.athoracsur.2004.04.082
   Ennker IC, 2009, J PLAST RECONSTR AES, V62, P1479, DOI 10.1016/j.bjps.2008.05.017
   Fernandez-Palacios J, 2010, J CARDIOVASC SURG, V51, P765
   Floros P, 2011, HEART LUNG CIRC, V20, P712, DOI 10.1016/j.hlc.2011.08.001
   Hollenbeak CS, 2000, CHEST, V118, P397, DOI 10.1378/chest.118.2.397
   Kaye AE, 2010, ANN PLAS SURG, V64, P658, DOI 10.1097/SAP.0b013e3181dba841
   Malmsjö M, 2007, PLAST RECONSTR SURG, V120, P1266, DOI 10.1097/01.prs.0000279326.84535.2d
   Martínez FQ, 2008, ARCH BRONCONEUMOL, V44, P113, DOI 10.1157/13115751
   Mochizuki Y, 2003, ANN PLAS SURG, V51, P423, DOI 10.1097/01.SAP.0000054249.95723.B9
   PAIROLERO PC, 1991, ANN SURG, V213, P583, DOI 10.1097/00000658-199106000-00008
   Poncelet AJ, 2008, EUR J CARDIO-THORAC, V33, P232, DOI 10.1016/j.ejcts.2007.11.016
   Puma F, 2003, J THORAC CARDIOV SUR, V126, P1998, DOI 10.1016/S0022-5223(03)00709-8
   Raja Shahzad G, 2007, Interact Cardiovasc Thorac Surg, V6, P523, DOI 10.1510/icvts.2007.157370
   Sachithanandan A, 2008, EUR J CARDIO-THORAC, V33, P673, DOI 10.1016/j.ejcts.2008.01.002
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Wong CHK, 2006, EUR J CARDIO-THORAC, V30, P148, DOI 10.1016/j.ejcts.2006.03.049
   Yasuura K, 1998, ANN SURG, V227, P455, DOI 10.1097/00000658-199803000-00019
   1994, PLAST RECONSTR SURG, V93, P1433
NR 23
TC 21
Z9 22
U1 0
U2 4
PU MEDICAL TRIBUNE INC
PI TOKYO
PA ED COMM ANNALS THORACIC CARDIOVASCULAR SURG, 2-1-30 KUDAN MINAMI,
   CHIYODA-KU, TOKYO, 102-0074, JAPAN
SN 1341-1098
EI 2186-1005
J9 ANN THORAC CARDIOVAS
JI Ann. Thorac. Cardiovasc. Surg.
PY 2019
VL 25
IS 2
BP 102
EP 110
DI 10.5761/atcs.oa.18-00115
PG 9
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA HU7GP
UT WOS:000465449500005
PM 30404980
OA gold
DA 2026-07-24
ER

PT J
AU Andres, T
   von Lübken, F
   Friemert, B
   Achatz, G
AF Andres, Torsten
   von Luebken, Falk
   Friemert, Benedikt
   Achatz, Gerhard
TI Vacuum-Assisted Closure in the Management of Degloving Soft Tissue
   Injury: A Case Report
SO JOURNAL OF FOOT & ANKLE SURGERY
LA English
DT Article
DE avulsion; degloving injury; foot; soft tissue defect; trauma;
   vacuum-assisted wound closure
ID FRACTURES
AB We report the case of a patient with an extensive degloving injury to his right foot involving severe subcutaneous soft tissue disruption and contamination. The initial treatment consisted of debridement, which was kept to a minimum, copious irrigation, primary wound closure at a few sites, and coverage of the remaining skin defects with vacuum-assisted closure (VAC) dressings. After a few weeks of VAC therapy for wound bed preparation, definitive coverage with a meshed skin graft was possible. Additional plastic surgical procedures were not required. At the last follow-up visit, the patient had no complaints and was able to participate in normal social life without limitations. Wounds that are grossly contaminated or associated with extensive soft tissue defects often require a multistage approach before delayed primary wound closure or plastic surgical procedures can be performed. Vacuum therapy can be used for temporary soft tissue coverage and has been shown to improve bacterial clearance, to increase local blood flow, and to promote granulation tissue formation. In contrast, plastic surgical procedures initially achieve safe and stable wound closure; however, the absence of sensitivity can lead to secondary problems. This is of particular relevance if the graft recipient site is subject to heavy stress and the restoration of function is of paramount importance, such as in the present case. Vacuum therapy is an effective and safe treatment of degloving injuries. We achieved a very good functional outcome, which was particularly important in view of the high stresses and strains to which a foot is exposed. (C) 2016 by the American College of Foot and Ankle Surgeons. All rights reserved.
C1 [Andres, Torsten; Friemert, Benedikt] German Armed Forces Hosp Ulm, Dept Orthopaed & Trauma Surg Reconstruct & Sept S, Oberer Eselsberg 40, D-89081 Ulm, Germany.
   [Andres, Torsten; Friemert, Benedikt; Achatz, Gerhard] German Soc Trauma Surg, Working Grp Ultrasound, Berlin, Germany.
   [von Luebken, Falk] German Armed Forces Hosp Ulm, Foot & Ankle Div, Dept Orthopaed & Trauma Surg Reconstruct & Sept S, D-89081 Ulm, Germany.
   [Achatz, Gerhard] German Armed Forces Hosp Ulm, Shoulder & Elbow Div, Dept Orthopaed & Trauma Surg Reconstruct & Sept S, D-89081 Ulm, Germany.
C3 Ulm University; Military Hospital Ulm; Ulm University; Military Hospital
   Ulm; Ulm University; Military Hospital Ulm
RP Andres, T (通讯作者)，German Armed Forces Hosp Ulm, Dept Orthopaed & Trauma Surg Reconstruct & Sept S, Oberer Eselsberg 40, D-89081 Ulm, Germany.
EM TorstenAndres@bundeswehr.org
RI /ABI-6295-2020
OI Anes, Torsten/0000-0002-2665-688X
CR Berger A, 2002, TSCHERNE UNFALLCHIRU, P183
   Damert HG, 2009, CHIRURG, V80, P448, DOI 10.1007/s00104-008-1586-7
   Ferbert T, 2004, ZENTRALBL CHIR, V129, P57
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   FREUNDLICH BD, 1987, J TRAUMA, V27, P453
   Geiger S, 2008, PLAST RECONSTR SURG, V122, P146, DOI 10.1097/PRS.0b013e3181773d19
   Josty IC, 2001, BRIT J PLAST SURG, V54, P363, DOI 10.1054/bjps.2000.3565
   Labler L, 2005, VAKUUMTHERAPIE GRUND, P103
   Leininger BE, 2006, J TRAUMA, V61, P1207, DOI 10.1097/01.ta.0000241150.15342.da
   Liu L, 2012, INT ORTHOP, V36, P1441, DOI 10.1007/s00264-011-1404-6
   Mischo M, 2006, ZENTRALBL CHIR, V131, P83
   Penn-Barwell Jowan G, 2011, Eplasty, V11, pe35
   Qu JF, 2013, EXP THER MED, V5, P1375, DOI 10.3892/etm.2013.999
   Ravari Hassan, 2013, J Cutan Aesthet Surg, V6, P17, DOI 10.4103/0974-2077.110091
   Shadgan B, 2015, J ORTHOP TRAUMATOL, V16, P185, DOI 10.1007/s10195-014-0330-y
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Wong LK, 2006, SOUTH MED J, V99, P628, DOI 10.1097/01.smj.0000217111.35160.09
NR 17
TC 6
Z9 10
U1 0
U2 5
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1067-2516
EI 1542-2224
J9 J FOOT ANKLE SURG
JI J. Foot Ankle Surg.
PD JUL-AUG
PY 2016
VL 55
IS 4
BP 852
EP 856
DI 10.1053/j.jfas.2015.12.002
PG 5
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA DO8YL
UT WOS:000378071300032
PM 26826925
DA 2026-07-24
ER

PT J
AU Bannasch, H
   Iblher, N
   Penna, V
   Torio, N
   Felmerer, G
   Stark, GB
   Momeni, A
AF Bannasch, H.
   Iblher, N.
   Penna, V.
   Torio, N.
   Felmerer, G.
   Stark, G. B.
   Momeni, A.
TI A critical evaluation of the concomitant use of the implantable Doppler
   probe and the vacuum assisted closure system in free tissue transfer
SO MICROSURGERY
LA English
DT Article; Proceedings Paper
CT Annual Meeting of the
   German-Society-for-Plastic-and-Reconstructive-Surgery
CY SEP 06-08, 2007
CL Hannover, GERMANY
SP German Soc Plast & Reconstruct Surg
ID NEGATIVE-PRESSURE DRESSINGS; MICROVASCULAR FREE FLAPS; THICKNESS
   SKIN-GRAFTS; LOWER-EXTREMITY; RECONSTRUCTION
AB Introduction of the Vacuum-Assisted Closure (V.A.C.) system has revolutionized the approach to a multitude of clinical settings. Yet, its use precludes adequate clinical monitoring of skin-grafted free flaps, thus, making a reliable monitoring system essential if broad clinical application is aspired. In a clinical study, the usefulness of the combination of the V.A.C. and implantable Doppler probe was critically evaluated in patients with microsurgical lower extremity reconstruction. We retrospectively analyzed the usefulness of the implantable Doppler probe in five consecutive patients treated in our department from January to July 2007. Inclusion criteria were lower extremity reconstruction by means of skin-grafted free tissue transfers with subsequent application of the V.A.C. device. Five consecutive patients (four males, one female) with a mean age of 37.8 years (range, 8-58 years) matched the criteria mentioned above. Of note, the two pediatric patients (8-year-old male and 12-year-old female) suffered from significant posttraumatic stress disorder necessitating concomitant psychological care by the Department of Psychiatry. All flaps healed uneventfully displaying no signs of vascular compromise. Interpretation of the Doppler signal was simple and well received by the nursing staff. The combination of V.A.C. and the implantable Doppler probe enhances patient comfort due to a reduction of the number of dressing changes while still allowing continuous free flap monitoring. Interpretation of the signal transmitted by the probe is simple and potentially reduces misinterpretations due to different levels of experience. (C) 2008 Wiley-Liss, Inc.
C1 [Bannasch, H.; Iblher, N.; Penna, V.; Torio, N.; Felmerer, G.; Stark, G. B.; Momeni, A.] Univ Freiburg, Med Ctr, Dept Plast & Hand Surg, D-79106 Freiburg, Germany.
C3 University of Freiburg
RP Bannasch, H (通讯作者)，Univ Freiburg, Med Ctr, Dept Plast & Hand Surg, Hugstetter Str 55, D-79106 Freiburg, Germany.
EM holger.bannasch@uniklinik-freiburg.de
RI Momeni, Arash/AAV-8300-2020
OI Momeni, Arash/0000-0002-6452-751X
CR Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Bannasch H, 2008, ANN PLAS SURG, V60, P386, DOI 10.1097/SAP.0b013e3180dc9a77
   Benacquista T, 1996, PLAST RECONSTR SURG, V98, P834, DOI 10.1097/00006534-199610000-00013
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Hallock GG, 2005, PLAST RECONSTR SURG, V116, P1839, DOI 10.1097/01.prs.0000188840.06911.06
   Hanasono MM, 2007, ANN PLAS SURG, V58, P573, DOI 10.1097/01.sap.0000237638.93453.66
   Hashimoto I, 2007, J RECONSTR MICROSURG, V23, P269, DOI 10.1055/s-2007-985208
   Keller A, 2007, J RECONSTR MICROSURG, V23, P189, DOI 10.1055/s-2007-974655
   KHOURI RK, 1989, J TRAUMA, V29, P1086, DOI 10.1097/00005373-198908000-00005
   Kind GM, 1998, PLAST RECONSTR SURG, V101, P1268, DOI 10.1097/00006534-199804050-00016
   Llanos S, 2006, ANN SURG, V244, P700, DOI 10.1097/01.sla.0000217745.56657.e5
   Momeni A, 2006, MICROSURG, V26, P515, DOI 10.1002/micr.20279
   MORYKWAS MJ, 2006, PLAST RECONSUR SUR S, V117, P126
   Repez A, 2008, J PLAST RECONSTR AES, V61, P71, DOI 10.1016/j.bjps.2007.04.003
   Rosenfeld WE, 2006, EUR J NEUROL, V13, P109
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Schoeller T, 2002, PLAST RECONSTR SURG, V110, P218, DOI 10.1097/00006534-200207000-00038
   Stokes TH, 2006, ANN PLAS SURG, V56, P649, DOI 10.1097/01.sap.0000202826.61782.c9
   SWARTZ WM, 1988, PLAST RECONSTR SURG, V81, P149, DOI 10.1097/00006534-198802000-00001
   SWARTZ WM, 1994, PLAST RECONSTR SURG, V93, P152, DOI 10.1097/00006534-199401000-00024
NR 20
TC 26
Z9 28
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0738-1085
EI 1098-2752
J9 MICROSURG
JI Microsurgery
PY 2008
VL 28
IS 6
BP 412
EP 416
DI 10.1002/micr.20512
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 354FN
UT WOS:000259624400005
PM 18623161
DA 2026-07-24
ER

PT J
AU Stremitzer, S
   Dal Borgo, A
   Wild, T
   Goetzinger, P
AF Stremitzer, Stefan
   Dal Borgo, Andrea
   Wild, Thomas
   Goetzinger, Peter
TI Successful bridging treatment and healing of enteric fistulae by
   vacuum-assisted closure (VAC) therapy and targeted drainage in patients
   with open abdomen
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Article
DE Secondary peritonitis; Enteric fistula; VAC; Bridging therapy
ID TEMPORARY ABDOMINAL CLOSURE; ENTEROCUTANEOUS FISTULAS; GASTROINTESTINAL
   FISTULAS; SURGICAL-MANAGEMENT; SEVERE PERITONITIS; SYSTEM; EXPERIENCE;
   SEPSIS; LAPAROSTOMY; FAILURE
AB The object of this study was to investigate the bridging treatment of enteric fistulae by vacuum-assisted closure (VAC) therapy in patients with open abdomen.
   We retrospectively analyzed patients who have been treated between 1 January 2007 and 31 December 2008 at the intensive care unit of the Department of General Surgery, Medical University Vienna. Control of the fistula was established by VAC therapy to bridge the patients to the time of the fistula resection.
   In the period of investigation, we treated nine (six men/three women) patients suffering from enteric fistulae with VAC therapy. The median age of the patients was 48 (range, 37-67) years. The median duration of VAC therapy was 76 (range, 53-128) days. The median length of stay in the intensive care unit was 44 (range, 25-127) days. The median APACHE II score was 23 (range, 18-25). The predicted mortality was 40%; the actual mortality was 11% (one patient). Primary fascial closure was achieved after median 91 (range, 89-92) days in three patients (33%) and secondary fascial closure after median 292 (range, 252-546) days in another three patients (33%). Fistulae were cured with VAC (five patients, 56%) and surgical resection (three patients, 33%). None of the patients developed a refistulation at the time of follow-up.
   Control of enteric fistulae by VAC therapy can lead to spontaneous fistula closure and is associated with a low mortality.
C1 [Stremitzer, Stefan; Dal Borgo, Andrea; Wild, Thomas; Goetzinger, Peter] Med Univ Vienna, Dept Gen Surg, A-1090 Vienna, Austria.
C3 Medical University of Vienna
RP Stremitzer, S (通讯作者)，Med Univ Vienna, Dept Gen Surg, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
EM stefan.stremitzer@meduniwien.ac.at
CR Alvarez C, 2000, WORLD J SURG, V24, P533, DOI 10.1007/s002689910086
   Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
   APRAHAMIAN C, 1990, J TRAUMA, V30, P719, DOI 10.1097/00005373-199006000-00011
   Arebi Naila, 2004, Clin Colon Rectal Surg, V17, P89, DOI 10.1055/s-2004-828655
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Campos ACL, 1999, J AM COLL SURGEONS, V188, P483, DOI 10.1016/S1072-7515(99)00038-1
   Carlson GL, 2003, P NUTR SOC, V62, P711, DOI 10.1079/PNS2003287
   Connolly PT, 2008, ANN SURG, V247, P440, DOI 10.1097/SLA.0b013e3181612c99
   Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
   Dellinger RP, 2008, CRIT CARE MED, V36, P296, DOI 10.1097/01.CCM.0000298158.12101.41
   Draus JM, 2006, SURGERY, V140, P570, DOI 10.1016/j.surg.2006.07.003
   Erdmann D, 2001, PLAST RECONSTR SURG, V108, P2066, DOI 10.1097/00006534-200112000-00036
   Fernandez L, 1996, J TRAUMA, V40, P258, DOI 10.1097/00005373-199602000-00014
   Haffejee AA, 2004, CURR OPIN CLIN NUTR, V7, P309, DOI 10.1097/00075197-200405000-00011
   Hesse U, 2001, GUT, V49, pIV11, DOI 10.1136/gut.49.suppl_4.iv11
   Horwood J, 2009, ANN ROY COLL SURG, V91, P681, DOI 10.1308/003588409X12486167520993
   KNAUS WA, 1985, CRIT CARE MED, V13, P818, DOI 10.1097/00003246-198510000-00009
   Makhdoom ZA, 2000, J CLIN GASTROENTEROL, V31, P195, DOI 10.1097/00004836-200010000-00003
   Memon Abdul Sattar, 2004, J Coll Physicians Surg Pak, V14, P25
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   Rao M, 2007, COLORECTAL DIS, V9, P266, DOI 10.1111/j.1463-1318.2006.01154.x
   SCRIPCARIU V, 1994, BRIT J SURG, V81, P1475, DOI 10.1002/bjs.1800811024
   Trevelyan S L, 2009, J Wound Care, V18, P24
   Wainstein Daniel Edgardo, 2008, World J Surg, V32, P430
   Wild T, 2006, ZBL CHIR, V131, pS111, DOI 10.1055/s-2006-921490
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
NR 26
TC 11
Z9 15
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0179-1958
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD MAY
PY 2011
VL 26
IS 5
BP 661
EP 666
DI 10.1007/s00384-010-1126-z
PG 6
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 750QD
UT WOS:000289562200016
PM 21212963
DA 2026-07-24
ER

PT J
AU Cattoni, DI
   Ravazzola, C
   Tüngler, V
   Wainstein, DE
   Chara, O
AF Cattoni, Diego I.
   Ravazzola, Constanza
   Tuengler, Victoria
   Wainstein, Daniel E.
   Chara, Osvaldo
TI Effect of intestinal pressure on fistula closure during vacuum assisted
   treatment: A computational approach
SO INTERNATIONAL JOURNAL OF SURGERY
LA English
DT Article
DE Enterocutaneous fistula; Intestinal pressure; Fistula radius;
   Simulation; Computational model
ID ENTEROCUTANEOUS FISTULAS; MANAGEMENT; MODEL; MANOMETRY; MOTILITY;
   GROWTH; MOTOR
AB Background: Enterocutaneous fistulae, pathological communications between the intestinal lumen and the abdominal skin, can arise as serious complication of gastrointestinal surgery. A current non-surgical treatment for this pathology involves topical application of sub-atmospheric pressure, also known as vacuum assisted closure (VAC). While this technique appears to be promising, surgeons report a number of cases in which its application fails to achieve fistula closure. Here, we evaluate the fistula's physical properties during the vacuum assisted closure process in a computational approach exploring the relevance of intraluminal intestinal pressure.
   Methods: A mathematical model formulated by differential equations based on tissue elasticity properties and principles of fluid mechanics was created and forcing functions were integrated to mimic intestinal pressure dynamics. A software to solve equations and to fit the model to experimentally obtained data was developed. This enabled simulations of vacuum assisted fistula closure under different intestinal pressure.
   Results: The simulation output indicates conditions, in which fistula closure can or cannot be expected suggesting favoured or impeded healing, respectively. When modifications of intestinal pressure, as observed in fistula accompanying pathologies, are integrated, the outcome of fistula closure changes considerably. Rise of intestinal pressure is associated with delay of fistula closure and temporary fistula radius augmentation, while reduction of intestinal pressure during sub-atmospheric pressure treatment contributes to a faster and direct fistula closure.
   Conclusion: From the model predictions, we conclude that administration of intestinal pressure decreasing compounds (e. g. butylscopolamine, glucagon) may improve VAC treatment, while intestinal pressure increasing drugs should be avoided. (C) 2011 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.
C1 [Cattoni, Diego I.] Univ Montpellier, CNRS, Ctr Biochim Struct, INSERM,U554,UMR 5048, F-34090 Montpellier, France.
   [Ravazzola, Constanza; Chara, Osvaldo] Univ Buenos Aires, Sch Med, Dept Physiol & Biophys, RA-1121 Buenos Aires, DF, Argentina.
   [Tuengler, Victoria] Charite Univ Med Berlin, Berlin, Germany.
   [Tuengler, Victoria] Tech Univ Dresden, Klin Kinder & Jugendmed, D-01307 Dresden, Germany.
   [Wainstein, Daniel E.] Gen Acute Hosp Dr E Tornu, RA-1427 Buenos Aires, DF, Argentina.
   [Chara, Osvaldo] Tech Univ Dresden, Ctr Informat Serv & High Performance Comp, D-01069 Dresden, Germany.
   [Chara, Osvaldo] UNLP, CONICET, Inst Phys Liquids & Biol Syst, RA-1900 La Plata, Argentina.
C3 Centre National de la Recherche Scientifique (CNRS); CNRS - National
   Institute for Biology (INSB); Institut National de la Sante et de la
   Recherche Medicale (Inserm); Universite de Montpellier; University of
   Buenos Aires; Free University of Berlin; Humboldt University of Berlin;
   Charite Universitatsmedizin Berlin; Technische Universitat Dresden;
   Technische Universitat Dresden; Consejo Nacional de Investigaciones
   Cientificas y Tecnicas (CONICET); National University of La Plata
RP Chara, O (通讯作者)，Tech Univ Dresden, Room 1024,Nothnitzer Str 46, D-01187 Dresden, Germany.
EM osvaldo.chara@tu-dresden.de
RI Tüngler, Victoria/AAA-2396-2022; Chara, Osvaldo/T-2798-2019
OI Tüngler, Victoria/0000-0003-3486-2824; Chara,
   Osvaldo/0000-0002-0868-2507; Cattoni, Diego I/0000-0002-0048-8531
FU National Council for Scientific and Technical Research (CONICET) of
   Argentina; CONICET
FX Funding was provided by the National Council for Scientific and
   Technical Research (CONICET) of Argentina. O.C. is career researcher
   from Consejo Nacional de Investigaciones Cientificas y Tecnicas
   (CONICET) of Argentina. This work was supported by grants from CONICET.
CR Adimy M, 2006, B MATH BIOL, V68, P2321, DOI 10.1007/s11538-006-9121-9
   Aggarwal Pakhee, 2008, Indian J Med Sci, V62, P179
   Akiho H, 2002, AM J PHYSIOL-GASTR L, V282, pG226, DOI 10.1152/ajpgi.2002.282.2.G226
   Antes G, 2003, RADIOLOGE, V43, P9, DOI 10.1007/s00117-002-0840-0
   Araujo RP, 2004, B MATH BIOL, V66, P1039, DOI 10.1016/j.bulm.2003.11.002
   BANWELL JG, 1981, GASTROENTEROLOGY, V80, P834
   Boulanger K, 2007, ACTA CHIR BELG, V107, P703, DOI 10.1080/00015458.2007.11680153
   Campos ACL, 1999, J AM COLL SURGEONS, V188, P483, DOI 10.1016/S1072-7515(99)00038-1
   Cattoni DI, 2008, B MATH BIOL, V70, P281, DOI 10.1007/s11538-007-9258-1
   Chaikomin R, 2007, AM J PHYSIOL-GASTR L, V292, pG1099, DOI 10.1152/ajpgi.00519.2006
   CHAPMAN R, 1964, AM J SURG, V108, P157, DOI 10.1016/0002-9610(64)90005-4
   Chara O, 2009, B MATH BIOL, V71, P1025, DOI 10.1007/s11538-008-9392-4
   CHERNISH SM, 1990, RADIOLOGY, V177, P145, DOI 10.1148/radiology.177.1.2204958
   Ferna⠁ndez ER, 1992, REV ARGENT CIR, V62, P117
   Gmora Scott, 2002, J Pediatr Surg, V37, pE28, DOI 10.1053/jpsu.2002.35438
   Hansen MB, 2002, PHYSIOL RES, V51, P541, DOI 10.33549/physiolres.930000.51.541
   Hernández JA, 2007, B MATH BIOL, V69, P1631, DOI 10.1007/s11538-006-9183-8
   Kornbluth A., 1998, Sleisenger Fordtrans Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, and Management, V2, P1708
   Li JS, 2003, CHINESE MED J-PEKING, V116, P171
   Pandolfino JE, 2000, GASTROENTEROLOGY, V118, pS32, DOI 10.1016/S0016-5085(00)70005-9
   Quigley EMM, 1997, DIGEST DIS SCI, V42, P2395, DOI 10.1023/A:1018803819455
   Rogalla P, 2005, RADIOLOGY, V236, P184, DOI 10.1148/radiol.2353040007
   Samsom M, 1998, NEUROGASTROENT MOTIL, V10, P139, DOI 10.1046/j.1365-2982.1998.00093.x
   Schecter WP, 2009, J AM COLL SURGEONS, V209, P484, DOI 10.1016/j.jamcollsurg.2009.05.025
   Schein M, 2008, WORLD J SURG, V32, P336, DOI 10.1007/s00268-007-9411-x
   Smye SW, 2002, MED ENG PHYS, V24, P565, DOI 10.1016/S1350-4533(02)00049-8
   SMYE SW, 1990, PHYS MED BIOL, V35, P103, DOI 10.1088/0031-9155/35/1/010
   Soffer EE, 1998, AM J GASTROENTEROL, V93, P1318
   THOMPSON DG, 1980, GUT, V21, P500, DOI 10.1136/gut.21.6.500
   Thumshirn M, 2007, ALIMENT PHARM THER, V26, P1399, DOI 10.1111/j.1365-2036.2007.03521.x
   Tiwary Satyendra K, 2006, World J Surg Oncol, V4, P63, DOI 10.1186/1477-7819-4-63
   Ventura AC, 2006, PHYS REV E, V74, DOI 10.1103/PhysRevE.74.011917
   Wainstein DE, 2011, INT J SURG, V9, P198, DOI 10.1016/j.ijsu.2010.11.009
   Wainstein Daniel Edgardo, 2008, World J Surg, V32, P430
NR 34
TC 3
Z9 3
U1 0
U2 6
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 1743-9191
EI 1743-9159
J9 INT J SURG
JI Int. J. Surg.
PY 2011
VL 9
IS 8
BP 662
EP 668
DI 10.1016/j.ijsu.2011.09.001
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 890TJ
UT WOS:000300167800017
PM 21945673
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Eginton, MT
   Brown, KR
   Seabrook, GR
   Towne, JB
   Cambria, RA
AF Eginton, MT
   Brown, KR
   Seabrook, GR
   Towne, JB
   Cambria, RA
TI A prospective randomized evaluation of negative-pressure wound dressings
   for diabetic foot wounds
SO ANNALS OF VASCULAR SURGERY
LA English
DT Article; Proceedings Paper
CT 13th Annual Winter Meeting of the Peripheral-Vascular-Surgery-Society
CY JAN 31-FEB 02, 2003
CL SNOWMASS, COLORADO
SP Peripheral Vasc Surg Soc
ID VACUUM-ASSISTED CLOSURE
AB Optimal treatment for large diabetic foot wounds is ill defined. The purpose of this study was to compare the rate of wound healing with the Vacuum Assisted Closure device(TM) (VAC) to conventional moist dressings in the treatment of large diabetic foot wounds. Diabetics with significant soft tissue defects of the foot were considered for enrollment. Patients were randomized to receive either moist gauze dressings or VAC treatments for 2 weeks, after which they were treated with the alternative dressing for an additional 2 weeks. Wounds were photographed weekly and wound dimensions calculated in a blinded fashion with spatial analysis software. Percent change in wound dimensions were calculated and compared for each weekly assessment and over 2 weeks of therapy with each dressing type. Ten patients were enrolled in the trial, but two were lost to follow-up and two were withdrawn. Complete data were available for analysis on seven wounds in six patients. Average length, width, and depth of the wounds at initiation of the trial was 7.7, 3.5, and 3.1 cm, respectively. Only the wound depth was significantly decreased over the weeks of the trial to 1.2 cm (p < 0.05). VAC dressings decreased the wound volume and depth significantly more than moist gauze dressings (59% vs. 0% and 49% vs. 8%, respectively). VAC dressings were associated with a decrease in all wound dimensions while wound length and width increased with moist dressings. In summary, over the first several weeks of therapy, VAC dressings decreased wound depth and volume more effectively than moist gauze dressings. Negative-pressure wound treatment may accelerate closure of large foot wounds in the diabetic patient.
C1 Med Coll Wisconsin, Dept Surg, Div Vasc Surg, Milwaukee, WI 53226 USA.
C3 Medical College of Wisconsin
RP Cambria, RA (通讯作者)，Med Coll Wisconsin, Dept Surg, Div Vasc Surg, 9200 W Wisconsin Ave, Milwaukee, WI 53226 USA.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bloomgarden ZT, 2001, DIABETES CARE, V24, P946, DOI 10.2337/diacare.24.5.946
   Evans D, 2001, BRIT J PLAST SURG, V54, P238, DOI 10.1054/bjps.2001.3547
   Joseph E, 2000, WOUNDS, V12, P60
   Langemo D K, 2001, Adv Skin Wound Care, V14, P190, DOI 10.1097/00129334-200107000-00011
   McCallon S K, 2000, Ostomy Wound Manage, V46, P28
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Peters EJG, 2001, DIABETES CARE, V24, P1799, DOI 10.2337/diacare.24.10.1799
   Philippidis TP, 1999, COMPOS STRUCT, V45, P41, DOI 10.1016/S0263-8223(99)00012-4
NR 9
TC 216
Z9 256
U1 0
U2 24
PU SPRINGER-VERLAG
PI NEW YORK
PA 175 FIFTH AVE, NEW YORK, NY 10010 USA
SN 0890-5096
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD DEC
PY 2003
VL 17
IS 6
BP 645
EP 649
DI 10.1007/s10016-003-0065-3
PG 5
WC Surgery; Peripheral Vascular Disease
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA 754CU
UT WOS:000187285800010
PM 14534844
DA 2026-07-24
ER

PT J
AU Yoshimoto, A
   Inoue, T
   Fujisaki, M
   Morizumi, S
   Suematsu, Y
AF Yoshimoto, Akihiro
   Inoue, Takafumi
   Fujisaki, Masayuki
   Morizumi, Sei
   Suematsu, Yoshihiro
TI Efficacy of vacuum-assisted closure therapy on rehabilitation during the
   treatment for surgical site infection after cardiovascular surgery
SO GENERAL THORACIC AND CARDIOVASCULAR SURGERY
LA English
DT Article
DE VAC treatment; Rehabilitation; Cardiovascular surgery; Surgical site
   infection
ID STERNAL WOUND-INFECTION; CARDIAC-SURGERY; POSTSTERNOTOMY MEDIASTINITIS;
   OPEN PACKING
AB Surgical site infection (SSI) after cardiovascular procedures is a severe complication, potentially leading to high morbidity and mortality. In addition, during the treatment of SSI, rehabilitation is delayed, which can severely impair postoperative recovery. The aim of this study was to assess the effect of vacuum-assisted closure (VAC) therapy on rehabilitation during the treatment of SSI after cardiovascular surgery.
   From January 2008 to March 2015, 10 patients underwent VAC therapy for SSI after cardiovascular operations. The patient characteristics, duration of VAC therapy, time interval from the implementation of VAC to physical therapy (PT) (T1), ambulation (T2) and walking (T3), functional independent measure (FIM), and maximum consecutive walking capacity (MCWC) were retrospectively analyzed.
   Nine patients underwent mid-sternal incision and one patient underwent thoraco-abdominal incision. The mean time interval from the beginning of VAC therapy to PT, ambulation, and walking was 0.38 +/- A 0.50, 0.63 +/- A 0.71, and 1.38 +/- A 1.86 days, respectively. The average FIM was 84.5 +/- A 14.0 at the beginning of VAC therapy and 106.7 +/- A 18.5 at the end of VAC therapy (P = 0.000494). On average, MCWC was 52.3 +/- A 54.6 m at the installation of VAC therapy and 189.7 +/- A 152.8 m at the completion of VAC therapy (P = 0.0169). FIM and MCWC improvement rate was better in VAC group than non-VAC group although these data are not suitable for statistical analysis because of a small sample size.
   Although further studies are warranted, VAC therapy may have a role in facilitating rehabilitation and improving the prognosis of SSI cases after major cardiovascular operations.
C1 [Yoshimoto, Akihiro; Inoue, Takafumi; Fujisaki, Masayuki; Morizumi, Sei; Suematsu, Yoshihiro] Tsukuba Mem Hosp, Dept Cardiovasc Surg, 1187-299 Kaname, Tsukuba, Ibaraki 3002622, Japan.
RP Yoshimoto, A (通讯作者)，Tsukuba Mem Hosp, Dept Cardiovasc Surg, 1187-299 Kaname, Tsukuba, Ibaraki 3002622, Japan.
EM yoshimoto0401@hotmail.co.jp
CR Finkelstein R, 2005, AM J INFECT CONTROL, V33, P450, DOI 10.1016/j.ajic.2005.07.002
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Fuchs U, 2005, ANN THORAC SURG, V79, P526, DOI 10.1016/j.athoracsur.2004.08.032
   Immer FF, 2005, ANN THORAC SURG, V80, P957, DOI 10.1016/j.athoracsur.2005.03.035
   Kawata M, 2011, J ARTIF ORGANS, V14, P159, DOI 10.1007/s10047-011-0555-y
   Kinoshita O, 2010, J ARTIF ORGANS, V13, P126, DOI 10.1007/s10047-010-0500-5
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Ridderstolpe L, 2001, EUR J CARDIO-THORAC, V20, P1168, DOI 10.1016/S1010-7940(01)00991-5
   Simek Martin, 2007, Biomedical Papers (Olomouc), V151, P295
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Suzuki T, 2015, GEN THORAC CARDIOVAS, V63, P86, DOI 10.1007/s11748-014-0451-5
   Vos RJ, 2012, INTERACT CARDIOV TH, V14, P17, DOI 10.1093/icvts/ivr049
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
NR 15
TC 8
Z9 8
U1 0
U2 5
PU SPRINGER JAPAN KK
PI TOKYO
PA CHIYODA FIRST BLDG EAST, 3-8-1 NISHI-KANDA, CHIYODA-KU, TOKYO, 101-0065,
   JAPAN
SN 1863-6705
EI 1863-6713
J9 GEN THORAC CARDIOVAS
JI Gen. Thorac. Cardiovasc. Surg.
PD AUG
PY 2016
VL 64
IS 8
BP 464
EP 469
DI 10.1007/s11748-016-0664-x
PG 6
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA DS9BY
UT WOS:000381078400005
PM 27262459
DA 2026-07-24
ER

PT J
AU Mooney, JF
   Argenta, LC
   Marks, MW
   Morykwas, MJ
   DeFranzo, AJ
AF Mooney, JF
   Argenta, LC
   Marks, MW
   Morykwas, MJ
   DeFranzo, AJ
TI Treatment of soft tissue defects in pediatric patients using the
   VACTM system
SO CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; WOUND CONTROL
AB Twenty-seven consecutive pediatric patients presenting to the orthopaedic surgery or plastic surgery services were reviewed after completion of wound care with the Vacuum Assisted Closure (V.A.C.(TM)) system. Each patient presented with complex soft tissue wounds requiring coverage procedures. Patients with acute wounds and wounds present after nonsuccessful attempts at surgical closure (dehisced incisions and failed flaps) were treated. All soft tissue defects healed without extensive coverage procedures using the V.A.C.(TM) system. In the majority of patients, use of the V.A.C.(TM) system produced a profuse bed of granulation tissue over all exposed bone, tendon, joint, and/or hardware, which could be covered with split thickness skin graft. Other patients were treated successfully with delayed primary closure, local flap advancement (one patient underwent a pedicled cross-leg flap), or by secondary intention. Use of the V.A.C.(TM) device is valuable in increasing the rate of granulation tissue formation and healing of extensive soft tissue injuries in pediatric patients. This vacuum system aids in the debridement of necrotic tissue and local soluble inflammatory mediators that may inhibit the proliferation of granulation tissue. These improvements in the local wound environment seem to accelerate wound healing compared with traditional methods. Before the development of the V.A.C.(TM) system, a minimum of nine patients within this group would have required free tissue transfer to obtain adequate coverage. The V.A.C.(TM) device seems to permit earlier coverage with local tissue or split-thickness skin grafting techniques, thereby decreasing the need for extensive microvascular tissue transfers in pediatric patients.
C1 Wayne State Univ, Sch Med, Dept Pediat Orthopaed Surg, Detroit, MI USA.
   Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC USA.
C3 Wayne State University; Wake Forest University
RP Mooney, JF (通讯作者)，Childrens Hosp Michigan, Dept Pediat Orthopaed Surg, 3901 Beaubien Blvd, Detroit, MI 48201 USA.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bucalo Brian, 1993, Wound Repair and Regeneration, V1, P181, DOI 10.1046/j.1524-475X.1993.10308.x
   Falanga Vincent, 1992, Journal of Dermatology (Tokyo), V19, P667
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   WYSOCKI AB, 1993, J INVEST DERMATOL, V101, P64, DOI 10.1111/1523-1747.ep12359590
   WYSOCKI AB, 1990, LAB INVEST, V63, P825
NR 7
TC 83
Z9 90
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0009-921X
J9 CLIN ORTHOP RELAT R
JI Clin. Orthop. Rel. Res.
PD JUL
PY 2000
IS 376
BP 26
EP 31
PG 6
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 329PL
UT WOS:000087915800006
DA 2026-07-24
ER

PT J
AU Gasperetti, T
   Welte, R
   Oberacher, H
   Marx, J
   Lorenz, I
   Schellongowski, P
   Staudinger, T
   Burgmann, K
   Eller, P
   Santner, T
   Griesmacher, A
   Pfisterer, H
   Eschertzhuber, S
   Aigner, M
   Joannidis, M
   Bellmann, R
AF Gasperetti, Tiziana
   Welte, Rene
   Oberacher, Herbert
   Marx, Jana
   Lorenz, Ingo
   Schellongowski, Peter
   Staudinger, Thomas
   Burgmann, Karin
   Eller, Philipp
   Santner, Tobias
   Griesmacher, Andrea
   Pfisterer, Hartwig
   Eschertzhuber, Stephan
   Aigner, Maria
   Joannidis, Michael
   Bellmann, Romuald
TI Penetration of echinocandins into wound secretion of critically ill
   patients
SO INFECTION
LA English
DT Article
DE Echinocandin antifungals; Target-site pharmacokinetics; Wound infection;
   Invasive candidiasis; Vacuum assisted closure therapy
AB Purpose Wound infections caused by Candida are life-threatening and difficult to treat. Echinocandins are highly effective against Candida species and recommended for treatment of invasive candidiasis. As penetration of echinocandins into wounds is largely unknown, we measured the concentrations of the echinocandins anidulafungin (AFG), micafungin (MFG), and caspofungin (CAS) in wound secretion (WS) and in plasma of critically ill patients. Methods We included critically ill adults with an indwelling wound drainage or undergoing vacuum-assisted closure therapy, who were treated with an echinocandin for suspected or proven invasive fungal infection. Concentrations were measured by liquid chromatography with UV (AFG and MFG) or tandem mass spectrometry detection (CAS). Results Twenty-one patients were enrolled. From eight patients, serial WS samples and simultaneous plasma samples were obtained within a dosage interval. AFG concentrations in WS amounted to < 0.025-2.25 mg/L, MFG concentrations were 0.025-2.53 mg/L, and CAS achieved concentrations of 0.18-4.04 mg/L. Concentrations in WS were significantly lower than the simultaneous plasma concentrations and below the MIC values of some relevant pathogens. Conclusion Echinocandin penetration into WS displays a high inter-individual variability. In WS of some of the patients, concentrations may be sub-therapeutic. However, the relevance of sub-therapeutic concentrations is unknown as no correlation has been established between concentration data and clinical outcome. Nevertheless, in the absence of clinical outcome studies, our data do not support the use of echinocandins at standard doses for the treatment of fungal wound infections, but underline the pivotal role of surgical debridement.
C1 [Gasperetti, Tiziana; Welte, Rene; Marx, Jana; Bellmann, Romuald] Med Univ Innsbruck, Dept Internal Med 1, Div Intens Care & Emergency Med, Clin Pharmacokinet Unit, Anichstr 35, A-6020 Innsbruck, Austria.
   [Oberacher, Herbert] Med Univ Innsbruck, Inst Legal Med, Innsbruck, Austria.
   [Oberacher, Herbert] Med Univ Innsbruck, Core Facil Metabol, Innsbruck, Austria.
   [Lorenz, Ingo] Med Univ Innsbruck, Univ Hosp Anaesthesia & Intens Care, Gen & Surg ICU, Innsbruck, Austria.
   [Schellongowski, Peter; Staudinger, Thomas; Burgmann, Karin] Med Univ Vienna, Dept Internal Med 1, Intens Care Unit, Vienna, Austria.
   [Eller, Philipp] Univ Hosp Graz, Dept Internal Med, Intens Care Unit, Graz, Austria.
   [Santner, Tobias; Griesmacher, Andrea; Pfisterer, Hartwig] Innsbruck Gen Hosp, Cent Inst Med & Chem Lab Diagnost, Innsbruck, Austria.
   [Eschertzhuber, Stephan] Univ Hosp Anaesthesia & Intens Care, Innsbruck Gen Hosp, Transplant ICU, Innsbruck, Austria.
   [Eschertzhuber, Stephan] Innsbruck Med Univ Innsbruck, Innsbruck, Austria.
   [Aigner, Maria] Med Univ Innsbruck, Inst Hyg & Med Microbiol, Innsbruck, Austria.
   [Joannidis, Michael] Med Univ Innsbruck, Dept Internal Med 1, Div Intens Care & Emergency Med, Innsbruck, Austria.
   [Eschertzhuber, Stephan] Dist Hosp Hall In Tyrol, Dept Anaesthesia & Crit Care, Hall In Tirol, Austria.
   [Aigner, Maria] INNPATH GmbH, Tirol Kliniken, Innsbruck, Austria.
C3 Medical University of Innsbruck; Medical University of Innsbruck;
   Medical University of Innsbruck; Medical University of Innsbruck;
   Medical University of Vienna; Medical University of Innsbruck; Medical
   University of Innsbruck; Medical University of Innsbruck
RP Bellmann, R (通讯作者)，Med Univ Innsbruck, Dept Internal Med 1, Div Intens Care & Emergency Med, Clin Pharmacokinet Unit, Anichstr 35, A-6020 Innsbruck, Austria.
EM romuald.bellmann@i-med.ac.at
RI Staudinger, Thomas/NYT-5567-2025; /J-3152-2012
OI Staudinger, Thomas/0000-0003-4311-4473; Bellmann,
   Romuald/0000-0003-2861-3258
FU University of Innsbruck; Medical University of Innsbruck; Austrian
   Science Fund (FWF) [KLI 565-B31]
FX Open access funding provided by University of Innsbruck and Medical
   University of Innsbruck. The study was supported by the Austrian Science
   Fund (FWF), Grant Number KLI 565-B31.
CR Akers KS, 2015, BMC INFECT DIS, V15, DOI 10.1186/s12879-015-0918-8
   Andes D, 2010, ANTIMICROB AGENTS CH, V54, P2497, DOI 10.1128/AAC.01584-09
   Andes D, 2011, ANTIMICROB AGENTS CH, V55, P2113, DOI 10.1128/AAC.01430-10
   [Anonymous], 2016, Clin Infect Dis, DOI DOI 10.1093/CID/CIV933
   Arikan AA, 2019, INFECT DIS-NOR, V51, P1, DOI 10.1080/23744235.2018.1518583
   Asensio MJ, 2015, INTENS CARE MED, V41, P371, DOI 10.1007/s00134-014-3586-z
   Aslier M, 2020, TURK ARCH OTORHINOL, V58, P56, DOI 10.5152/tao.2020.4927
   Bellmann R, 2017, INFECTION, V45, P737, DOI 10.1007/s15010-017-1042-z
   Betts RF, 2009, CLIN INFECT DIS, V48, P1676, DOI 10.1086/598933
   Felton T, 2014, CLIN MICROBIOL REV, V27, P68, DOI 10.1128/CMR.00046-13
   García-de-Lorenzo A, 2016, ANTIMICROB AGENTS CH, V60, P5914, DOI 10.1128/AAC.00727-16
   Lat A, 2010, ANTIMICROB AGENTS CH, V54, P943, DOI 10.1128/AAC.01294-09
   Lempers VJ, 2015, ANTIMICROB AGENTS CH, V59, P4403, DOI 10.1128/AAC.00623-15
   Liu P, 2013, ANTIMICROB AGENTS CH, V57, P1672, DOI 10.1128/AAC.02139-12
   Mainas E, 2020, J ANTIMICROB CHEMOTH, V75, P2969, DOI 10.1093/jac/dkaa265
   Malani PN, 2002, CLIN INFECT DIS, V35, P1316, DOI 10.1086/344192
   McGraw C, 2019, INJURY, V50, P2234, DOI 10.1016/j.injury.2019.10.027
   Nguyen TH, 2007, J ANTIMICROB CHEMOTH, V60, P100, DOI 10.1093/jac/dkm125
   Palackic A, 2021, SURG INFECT, V22, P83, DOI 10.1089/sur.2020.299
   Pfaller MA, 2017, INT J ANTIMICROB AG, V50, P352, DOI 10.1016/j.ijantimicag.2017.03.028
   Rodriguez CJ, 2018, MIL MED, V183, P142, DOI 10.1093/milmed/usy079
   Sasaki J, 2014, EUR J DRUG METAB PH, V39, P93, DOI 10.1007/s13318-013-0146-9
   Sasaki J, 2012, ANTIMICROB AGENTS CH, V56, P1113, DOI 10.1128/AAC.05381-11
   Smith BS, 2012, CHEST, V141, P1327, DOI 10.1378/chest.11-1396
   Welte R, 2020, J CHROMATOGR B, V1139, DOI 10.1016/j.jchromb.2019.121937
   Yamada N, 2011, J INFECT CHEMOTHER, V17, P731, DOI 10.1007/s10156-011-0240-3
NR 26
TC 4
Z9 4
U1 0
U2 6
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0300-8126
EI 1439-0973
J9 INFECTION
JI Infection
PD AUG
PY 2021
VL 49
IS 4
BP 747
EP 755
DI 10.1007/s15010-021-01604-x
EA APR 2021
PG 9
WC Infectious Diseases
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases
GA TQ1VF
UT WOS:000641624300001
PM 33877638
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Yasuda, JL
   Staffa, SJ
   Clark, SJ
   Ngo, PD
   Zendejas, B
   Hamilton, TE
   Jennings, RW
   Manfredi, MA
AF Yasuda, Jessica L.
   Staffa, Steven J.
   Clark, Susannah J.
   Ngo, Peter D.
   Zendejas, Benjamin
   Hamilton, Thomas E.
   Jennings, Russell W.
   Manfredi, Michael A.
TI Endoscopic incisional therapy and other novel strategies for effective
   treatment of congenital esophageal stenosis
SO JOURNAL OF PEDIATRIC SURGERY
LA English
DT Article
DE Endoscopic incisional therapy; Esophageal stent; Esophageal vacuum
   assisted closure
ID CLINICAL CHARACTERISTICS; MANAGEMENT; DISTAL
AB Background & aims: Congenital esophageal stenosis (CES) is an inborn condition of the esophagus that can be refractory to endoscopic dilation. Surgical intervention is not curative, with patients experiencing frequent ongoing need for therapy for anastomotic stricture postoperatively. We hypothesized that novel methods of endoscopic CES management including endoscopic incisional therapy (EIT) would lead to less surgical intervention.
   Methods: We retrospectively reviewed the medical records of all patients with CES treated by our tertiary care center who had at least one endoscopy between July 2007 and July 2019. Statistical comparison of cohorts who underwent advanced endoscopic therapy involving EIT versus traditional endoscopic therapy with balloon dilation was performed. Primary outcome measure was need for surgical intervention.
   Results: Thirty-six patients with CES met inclusion criteria. Thirty-four ever had at least one endoscopic intervention such as balloon dilation, steroid injection, stenting, and/or endoscopic incisional therapy (EIT) at their CES. Esophageal vacuum assisted closure (EVAC) was used for treatment or prevention of esophageal leak. Odds of surgical intervention were significantly lower in the group who received therapeutic endoscopy with EIT (odds ratio (OR) 0.1; p = 0.007). Clinical feeding outcomes were similar in the endoscopic and surgical management groups. Odds of complications after therapeutic endoscopies involving EIT were significantly greater than those without EIT (odds ratio 6.39; 95% confidence interval (2.34, 17.44); p < 0.001), though our rates of esophageal leak significantly decreased over time as our use of EVAC increased (Spearman's rho = -0.884; p = 0.004).
   Conclusion: Complementary endoscopic techniques such as EIT broaden the toolbox of the treating physician and may allow for avoidance of surgery in CES. (c) 2020 Elsevier Inc. All rights reserved.
C1 [Yasuda, Jessica L.; Ngo, Peter D.; Manfredi, Michael A.] Boston Childrens Hosp, Div Gastroenterol Hepatol & Nutr, Boston, MA USA.
   [Clark, Susannah J.; Zendejas, Benjamin; Hamilton, Thomas E.; Jennings, Russell W.] Boston Childrens Hosp, Dept Gen Surg, Boston, MA USA.
   [Staffa, Steven J.] Boston Childrens Hosp, Dept Anesthesiol Crit Care & Pain Med, Boston, MA USA.
C3 Harvard University; Harvard University Medical Affiliates; Boston
   Children's Hospital; Harvard University; Harvard University Medical
   Affiliates; Boston Children's Hospital; Harvard University; Harvard
   University Medical Affiliates; Boston Children's Hospital
RP Yasuda, JL (通讯作者)，300 Longwood Ave, Boston, MA 02115 USA.
EM Jessica.Yasuda@childrens.harvard.edu
RI Hamilton, Thomas/GQB-4837-2022
OI Clark, Susannah/0000-0003-4873-0582
CR Amae S, 2003, J PEDIATR SURG, V38, P565, DOI 10.1053/jpsu.2003.50123
   Bocus P, 2011, GASTROINTEST ENDOSC, V74, P204, DOI 10.1016/j.gie.2011.01.071
   Kawahara H, 2001, SURGERY, V129, P29, DOI 10.1067/msy.2001.109064
   Kouchi K, 2002, J PEDIATR SURG, V37, P934, DOI 10.1053/jpsu.2002.32921
   Manfredi MA, 2018, J PEDIATR GASTR NUTR, V67, P706, DOI 10.1097/MPG.0000000000002073
   Manfredi MA, 2018, J PEDIATR GASTR NUTR, V67, P464, DOI 10.1097/MPG.0000000000002008
   Michaud L, 2013, ORPHANET J RARE DIS, V8, DOI 10.1186/1750-1172-8-186
   NEILSON IR, 1991, J PEDIATR SURG, V26, P478, DOI 10.1016/0022-3468(91)90999-A
   Nihoul-F C, 1987, Pediatr Surg Int, V2, P86, DOI [DOI 10.1007/BF00174179, 10.1007/BF00174179]
   Quiros JA, 2013, J PEDIATR GASTR NUTR, V56, pE14, DOI 10.1097/MPG.0b013e31826a9086
   Romeo E, 2011, J PEDIATR SURG, V46, P838, DOI 10.1016/j.jpedsurg.2011.02.010
   Suzuhigashi M, 2017, PEDIATR SURG INT, V33, P1035, DOI 10.1007/s00383-017-4133-0
   Takamizawa S, 2002, J PEDIATR SURG, V37, P197, DOI 10.1053/jpsu.2002.30254
   Terui K, 2005, ENDOSCOPIC MANAGEMEN, DOI [10.4253/wjge.v7.i3, DOI 10.4253/WJGE.V7.I3]
   YEUNG CK, 1992, J PEDIATR SURG, V27, P852, DOI 10.1016/0022-3468(92)90382-H
NR 15
TC 18
Z9 26
U1 0
U2 4
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0022-3468
EI 1531-5037
J9 J PEDIATR SURG
JI J. Pediatr. Surg.
PD NOV
PY 2020
VL 55
IS 11
BP 2342
EP 2347
DI 10.1016/j.jpedsurg.2020.01.013
PG 6
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA PF3PI
UT WOS:000598970400014
PM 32057439
DA 2026-07-24
ER

PT J
AU van Hensbroek, PB
   Wind, J
   Dijkgraaf, MGW
   Busch, ORC
   Goslings, JC
AF van Hensbroek, Pieter Boele
   Wind, Jan
   Dijkgraaf, Marcel G. W.
   Busch, Olivier R. C.
   Goslings, J. Carel
TI Temporary Closure of the Open Abdomen: A Systematic Review on Delayed
   Primary Fascial Closure in Patients with an Open Abdomen
SO WORLD JOURNAL OF SURGERY
LA English
DT Article
ID ABDOMINAL COMPARTMENT SYNDROME; VACUUM-ASSISTED CLOSURE; DAMAGE CONTROL
   LAPAROTOMY; PACK TECHNIQUE; WOUND CLOSURE; WALL RECONSTRUCTION; OPEN
   MANAGEMENT; TRAUMA PATIENTS; VENTRAL HERNIA; MARLEX MESH
AB Background This study was designed to systematically review the literature to assess which temporary abdominal closure (TAC) technique is associated with the highest delayed primary fascial closure (FC) rate. In some cases of abdominal trauma or infection, edema or packing precludes fascial closure after laparotomy. This "open abdomen'' must then be temporarily closed. However, the FC rate varies between techniques.
   Methods The Cochrane Register of Controlled Trials, MEDLINE, and EMBASE databases were searched until December 2007. References were checked for additional studies. Search criteria included (synonyms of) "open abdomen,'' "fascial closure,'' "vacuum,'' "reapproximation,'' and "ventral hernia.'' Open abdomen was defined as "the inability to close the abdominal fascia after laparotomy.'' Two reviewers independently extracted data from original articles by using a predefined checklist.
   Results The search identified 154 abstracts of which 96 were considered relevant. No comparative studies were identified. After reading them, 51 articles, including 57 case series were included. The techniques described were vacuum-assisted closure (VAC; 8 series), vacuum pack (15 series), artificial burr (4 series), Mesh/sheet (16 series), zipper (7 series), silo (3 series), skin closure (2 series), dynamic retention sutures (DRS), and loose packing (1 series each). The highest FC rates were seen in the artificial burr (90%), DRS (85%), and VAC (60%). The lowest mortality rates were seen in the artificial burr (17%), VAC (18%), and DRS (23%).
   Conclusions These results suggest that the artificial burr and the VAC are associated with the highest FC rates and the lowest mortality rates.
C1 [van Hensbroek, Pieter Boele; Wind, Jan; Busch, Olivier R. C.; Goslings, J. Carel] Acad Med Ctr, Dept Surg, NL-1100 DD Amsterdam, Netherlands.
   [Dijkgraaf, Marcel G. W.] Acad Med Ctr, Dept Clin Epidemiol & Biostat, NL-1100 DD Amsterdam, Netherlands.
C3 University of Amsterdam; Academic Medical Center Amsterdam; University
   of Amsterdam; Academic Medical Center Amsterdam
RP van Hensbroek, PB (通讯作者)，Acad Med Ctr, Dept Surg, POB 22660,Room G4-150, NL-1100 DD Amsterdam, Netherlands.
EM p.boelevanhensbroek@amc.uva.nl
RI Dijkgraaf, Marcel/G-6663-2011; Busch, Olivier/AAC-3650-2020
FU Siemens Netherlands; ZonMw [945-06-901]
FX P. Boele van Hensbroek was supported by an unrestricted grant from
   Siemens Netherlands N. V., and J. Wind was supported by a grant
   (945-06-901) from ZonMw.
CR AKERS DL, 1991, J VASC SURG, V14, P48
   [Anonymous], 2000, ACTA CHIRURG AUSTRIA
   APRAHAMIAN C, 1990, J TRAUMA, V30, P719, DOI 10.1097/00005373-199006000-00011
   BAKER SP, 1974, J TRAUMA, V14, P187, DOI 10.1097/00005373-197403000-00001
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   BOSE SM, 1991, AUST NZ J SURG, V61, P385, DOI 10.1111/j.1445-2197.1991.tb00240.x
   Bosscha K, 2000, EUR J SURG, V166, P44
   BROCK WB, 1995, AM SURGEON, V61, P30
   Chavarria-Aguilar M, 2004, J TRAUMA, V56, P560, DOI 10.1097/01.TA.0000115065.39699.6A
   COHN SM, 1995, J TRAUMA, V39, P978, DOI 10.1097/00005373-199511000-00026
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   CUESTA MA, 1991, WORLD J SURG, V15, P74, DOI 10.1007/BF01658968
   DeFranzo AJ, 2006, CLIN PLAST SURG, V33, P213, DOI 10.1016/j.cps.2005.12.007
   Doyon A, 2001, Colorectal Dis, V3, P115, DOI 10.1046/j.1463-1318.2001.00214.x
   DUFF JH, 1981, SURGERY, V90, P774
   *DUTCH COCHR CTR, 2005, THER CHECKL DUTCH EX
   FANSLER RF, 1995, AM J SURG, V170, P15, DOI 10.1016/S0002-9610(99)80244-X
   Foy HM, 2003, AM J SURG, V185, P498, DOI 10.1016/S0002-9610(03)00059-X
   Hadeed JG, 2007, AM SURGEON, V73, P10
   HANNON RJ, 1992, BRIT J SURG, V79, P820, DOI 10.1002/bjs.1800790838
   Howdieshell TR, 2004, AM J SURG, V188, P301, DOI 10.1016/j.amjsurg.2004.03.007
   HUBENS G, 1994, ACTA CHIR BELG, P176
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   Keramati M, 2008, BURNS, V34, P493, DOI 10.1016/j.burns.2007.06.024
   Koniaris LG, 2001, ARCH SURG-CHICAGO, V136, P1359, DOI 10.1001/archsurg.136.12.1359
   Kushimoto S, 2007, WORLD J SURG, V31, P2, DOI 10.1007/s00268-006-0282-3
   Labler L, 2004, ZBL CHIR, V129, pS14, DOI 10.1055/s-2004.822668
   Losanoff J, 1997, AM J SURG, V173, P134, DOI 10.1016/S0002-9610(96)00411-4
   Mayberry JC, 2004, J TRAUMA, V57, P157, DOI 10.1097/01.TA.0000102411.69521.80
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   Nagy KK, 1996, AM SURGEON, V62, P331
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   Oetting P, 2006, CHIRURG, V77, P586, DOI 10.1007/s00104-006-1200-9
   OHMANN C, 1993, EUR J SURG, V159, P267
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   PHILLIPS B, 2008, LEVELS EVIDENCE
   Rasmussen TE, 2002, J VASC SURG, V35, P246, DOI 10.1067/mva.2002.120384
   Schachtrupp A, 2002, Hernia, V6, P102
   Sherck J, 1998, AM SURGEON, V64, P854
   SINGH VP, 1993, J PLANT GROWTH REGUL, V12, P1, DOI 10.1007/BF00193671
   Smith LA, 1997, AM SURGEON, V63, P1102
   SMITH PC, 1992, J TRAUMA, V32, P16, DOI 10.1097/00005373-199201000-00004
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   Stonerock CE, 2003, AM SURGEON, V69, P1030
   Sugrue M, 1998, J TRAUMA, V45, P914, DOI 10.1097/00005373-199811000-00013
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Töns C, 2000, CHIRURG, V71, P918, DOI 10.1007/s001040051156
   Tremblay LN, 2001, AM J SURG, V182, P670, DOI 10.1016/S0002-9610(01)00805-4
   van As AB, 2007, ACTA CLIN BELG, V62, P215, DOI 10.1179/acb.2007.62.s1.029
   vanGoor H, 1997, EUR J SURG, V163, P61
   Wilde JM, 2007, ANN ROY COLL SURG, V89, P57, DOI 10.1308/003588407X155446
   WOUTERS DB, 1983, SURG GYNECOL OBSTET, V156, P609
   Yeh KA, 1996, SOUTHERN MED J, V89, P497, DOI 10.1097/00007611-199605000-00010
   Zingales F, 2001, Chir Ital, V53, P821
NR 56
TC 236
Z9 255
U1 0
U2 10
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD FEB
PY 2009
VL 33
IS 2
BP 199
EP 207
DI 10.1007/s00268-008-9867-3
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 430OF
UT WOS:000264997700006
PM 19089494
OA Green Submitted, Green Published, hybrid
DA 2026-07-24
ER

PT J
AU Holle, G
   Riedel, K
   von Gregory, H
   Gazyakan, E
   Raab, N
   Germann, G
AF Holle, G.
   Riedel, K.
   von Gregory, H.
   Gazyakan, E.
   Raab, N.
   Germann, G.
TI Vacuum-assisted closure therapy. Current status and basic research
SO UNFALLCHIRURG
LA German
DT Article
DE VAC therapy; wound treatment; mechanical cell stimulation; soft tissue
   defects; cellular effect
ID SUBATMOSPHERIC PRESSURE; WOUND THERAPY
AB The gap between the broad clinical use of vacuum-assisted closure therapy (VT) and knowledge of the physiological mechanisms leading to its effectiveness is great. The value of the technique and its future development are dependent on research into these mechanisms.
   A meta-analysis evaluating the results of basic research on the effectiveness of VT was carried out based on peer reviewed publications. This is considered in relation to other therapeutic approaches of basic research to wound healing (growth factors etc.). Our study includes a concise description of the scientific background to the mechanisms of cell stimulation using basic work on tissue expansion, bone, vessel and nerve distraction as well as in vitro cell stimulation. Evaluation of the scientific data on all known effects of VT was made based on the results from experimental animal studies, the results of randomized clinical studies, observations on clinical applications and case reports. Assessment of the studies was based on design and significance as well as the appraisal of our own clinical experience. Data involving cellular effects (proliferation, synthesis, wound healing), systemic effects (mediators, systemic inflammatory disease), extracellular effects (perfusion, edema, local wound environment, stabilization, barriers) and complex effects of VT (inflammation, matrix function, blood supply) were examined.
   Systematic analysis of the data allows scientifically interested surgeons rapid access to the theme, the first, to this extent, extensive overview of the current scientific situation as well as a comprehensive bibliography for all areas involving the theme of mechanical cell stimulation. The authors list major areas for future research and encourage the development of multicenter studies.
C1 Heidelberg Univ, Klin Plast & Handchirurg, Schwerbrandverletztenzentrum, Klin Hand Plast & Reconstrukt Chirurg, D-67071 Ludwigshafen, Germany.
C3 Ruprecht Karls University Heidelberg
RP Holle, G (通讯作者)，Heidelberg Univ, Klin Plast & Handchirurg, Schwerbrandverletztenzentrum, Klin Hand Plast & Reconstrukt Chirurg, Ludwig Guttmann Str 13, D-67071 Ludwigshafen, Germany.
EM plastic-holle@web.de
RI Gazyakan, Emre/HLW-5585-2023
CR Adams T.S, 2004, TOPICAL NEGATIVE PRE, P212
   [Anonymous], WOUND REPAIR REG
   Banwell P, 2004, TOPICAL NEGATIVE PRE, P214
   BANWELL PE, 2007, UNPUB J WOUND CARE
   Büttgenbach S, 2001, MICROSYST TECHNOL, V7, P165, DOI 10.1007/s005420000082
   EGNITON MT, 2003, ANN VASC SURG, V13, P27
   Fabian TS, 2000, AM SURGEON, V66, P1136
   Fleischmann W, 1998, UNFALLCHIRURG, V101, P649, DOI 10.1007/s001130050318
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   Gouttefangeas C, 2001, CLIN EXP IMMUNOL, V124, P398, DOI 10.1046/j.1365-2249.2001.01547.x
   Isago T, 2003, J DERMATOL, V30, P596, DOI 10.1111/j.1346-8138.2003.tb00441.x
   Joseph E, 2000, WOUNDS, V12, P60
   Kamolz LP, 2004, BURNS, V30, P253, DOI 10.1016/j.burns.2003.12.003
   Kremers L, 2003, WOUND REPAIR REGEN, V11
   MCCALLON KS, 2000, OSTOMY WOUND MANAG, V46, P28
   Miller Quintessa, 2004, Curr Surg, V61, P205, DOI 10.1016/j.cursur.2003.07.015
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Rejzek A, 1998, ACTA CHIR AUST     S, V150, P12
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Schrank C, 2004, ZENTRALBLATT CHIR, V129, P59
   Shi W, 2003, SURF ENG, V19, P279, DOI [10.1179/026708403322499209, 10.1179/026708403225006221]
   VONFRITSCHEN U, 2002, K DTSCH GESS CHIR, V119
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P244, DOI 10.1111/j.1067-1927.2004.012117.x
   Walgenbach KJ, 2000, Z FLUGWISS WELTRAUM, V13, P9
   Wanner MB, 2003, SCAND J PLAST RECONS, V37, P28
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Zoch G, 2004, ZENTRALBLATT CHIR S, V129, P80
NR 30
TC 24
Z9 26
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0177-5537
EI 1433-044X
J9 UNFALLCHIRURG
JI Unfallchirurg
PD JUN
PY 2007
VL 110
IS 6
BP 490
EP 504
DI 10.1007/s00113-007-1267-x
PG 15
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA 178YY
UT WOS:000247257500002
PM 17546436
DA 2026-07-24
ER

PT J
AU Prince, N
   Blackburn, S
   Murad, G
   Mast, B
   Sapountzis, S
   Shaw, C
   Werning, J
   Singhal, D
AF Prince, Noah
   Blackburn, Spiros
   Murad, Gregory
   Mast, Bruce
   Sapountzis, Stamatis
   Shaw, Christiana
   Werning, John
   Singhal, Dhruv
TI Vacuum-Assisted Closure Therapy to the Brain A Safe Method for Wound
   Temporization in Composite Scalp and Calvarial Defects
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article; Proceedings Paper
CT 57th Annual Meeting of the
   South6eastern-Society-of-Plastic-and-Reconstructive-Surgeons
CY JUN 08-12, 2014
CL Nassau, BAHAMAS
SP SE Soc Plast & Reconstruct Surg
ID INFECTIONS; DURA
AB Background
   When composite scalp and calvarial defects with dural or cortical brain exposure are encountered, active infection or indeterminate oncologic margins complicate the timing of scalp reconstruction. The purpose of this study was to evaluate the safety and efficacy of vacuum-assisted closure (VAC) therapy as a temporizing measure in these complex scalp defects with dural or cortical brain exposure and a hostile local wound environment.
   Methods
   From December 2012 to December 2013, all composite scalp and calvarial defects reconstructed by the senior author (D.S.) were reviewed and 10 cases were identified. Five of these cases were temporized with VAC therapy. The medical records of these patients were reviewed.
   Results
   Five patients (mean age, 66.2 years) with composite scalp and calvarial defects were temporized with VAC therapy. The indications for delay included gross wound infection in 4 patients and an indeterminate intraoperative oncologic margin. The average size of the scalp and calvarial defects measured 123 and 49 cm(2), respectively. One patient underwent VAC therapy over exposed cortical brain with a dural defect measuring 25 cm(2). The average time between the initial operation and definitive reconstruction was 4.8 days. The average daily VAC output was 74 mL. Reconstructive methods included 1 free flap, 2 scalp rotational advancement flaps, and readvancement of 2 prior free flaps. At an average follow-up of 32 weeks, 1 patient developed a subcentimeter postoperative wound breakdown that was treated successfully with an incisional VAC.
   Conclusions
   We found the use of VAC therapy applied directly to the dura or cortical brain as a safe and effective technique for short-term wound temporization in the setting of indeterminate oncologic margins or active infection.
C1 [Prince, Noah; Mast, Bruce; Singhal, Dhruv] Univ Florida, Dept Surg, Div Plast & Reconstruct Surg, Sch Med, Gainesville, FL 32610 USA.
   [Blackburn, Spiros; Murad, Gregory] Univ Florida, Sch Med, Dept Neurosurg, Gainesville, FL 32610 USA.
   [Sapountzis, Stamatis] China Med Univ Hosp, Dept Plast Surg, Taichung, Taiwan.
   [Shaw, Christiana] Univ Florida, Sch Med, Dept Surg, Div Surg Oncol, Gainesville, FL 32610 USA.
   [Werning, John] Univ Florida, Sch Med, Dept Otolaryngol, Gainesville, FL 32610 USA.
C3 State University System of Florida; University of Florida; State
   University System of Florida; University of Florida; China Medical
   University Taiwan; China Medical University Hospital - Taiwan; State
   University System of Florida; University of Florida; State University
   System of Florida; University of Florida
RP Singhal, D (通讯作者)，Univ Florida, Dept Surg, Div Plast & Reconstruct Surg, POB 100138, Gainesville, FL 32610 USA.
EM dhruv.singhal@surgery.ufl.edu
OI Shaw, Christiana/0000-0002-7522-0556; BLACKBURN,
   SPIROS/0000-0003-2902-5079
CR Bartels CG, 2001, HAUTARZT, V52, P653
   Colwell AS, 2004, ANN PLAS SURG, V52, P49, DOI 10.1097/01.sap.0000099960.68038.53
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Hardwicke Joseph, 2006, Int J Low Extrem Wounds, V5, P101, DOI 10.1177/1534734606288576
   Khan MAA, 2010, J PLAST RECONSTR AES, V63, P2168, DOI 10.1016/j.bjps.2010.03.017
   Marathe US, 2004, LARYNGOSCOPE, V114, P961, DOI 10.1097/00005537-200406000-00001
   Powers AK, 2013, J NEUROSURG, V118, P302, DOI 10.3171/2012.10.JNS112241
   Subotic U, 2011, NEUROSURGERY, V68, pE1481, DOI 10.1227/NEU.0b013e318210c7fb
NR 8
TC 17
Z9 19
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD JUN
PY 2015
VL 74
SU 4
BP S218
EP S221
DI 10.1097/SAP.0000000000000374
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA CQ4IC
UT WOS:000360567200009
PM 25978553
DA 2026-07-24
ER

PT J
AU Mentula, P
AF Mentula, P.
TI Non-traumatic causes and the management of the open abdomen
SO MINERVA CHIRURGICA
LA English
DT Article
DE Decompression, surgical; Peritonitis; Pancreatitis, acute necrotizing;
   Surgical wound dehiscence; Aortic rupture
ID ABDOMINAL COMPARTMENT SYNDROME; DIRECT PERITONEAL RESUSCITATION;
   VACUUM-ASSISTED CLOSURE; PRIMARY FASCIAL CLOSURE; DELAYED PRIMARY
   CLOSURE; INTRAABDOMINAL HYPERTENSION; DAMAGE-CONTROL; SEPARATION
   TECHNIQUE; TRAUMA PATIENTS; WOUND CLOSURE
AB The open abdomen is increasingly used for the treatment and prevention of abdominal compartment syndrome. The leading non-traumatic conditions that may cause abdominal compartment syndrome requiring surgical decompression include secondary peritonitis, ruptured abdominal aortic aneurysm and severe acute pancreatitis. Patients may also end up with the open abdomen when the laparotomy wound cannot be closed without tension because of excessive visceral swelling. Also, surgical complications such as laparotomy wound dehiscence, may require temporary abdominal closure techniques. In critically ill surgical patients and in situations when second-look laparotomy is mandatory the open abdomen can be utilized in a preventive manner like in damage control trauma surgery. Underlying disease and the indication for the open abdomen significantly contributes to outcome of patient with open abdomen. Non-traumatic aetiology of the open abdomen is associated with lower likelihood of primary fascial closure and higher rate of open abdomen related complications compared with traumatic aetiology. A number of temporal abdominal closure techniques have been described. Ideally, temporal abdominal closure technique should prevent the development of recurrent abdominal compartment syndrome and facilitate later primary fascia closure with low complication rate. Although fascial closure rate varies between techniques, there are few evidence-based data to support one technique over another. However, recent evolution of temporary abdominal closure techniques have decreased the number of patients with frozen abdomen and reduced the need for planned hernia management. Highest fascial closure rates have been achieved with vacuum-assisted closure systems and systems that provide continuous fascial traction.
C1 Helsinki Univ Cent Hosp, Dept Gastrointestinal Surg, Helsinki 00029, Finland.
C3 University of Helsinki; Helsinki University Central Hospital
RP Mentula, P (通讯作者)，Helsinki Univ Cent Hosp, Dept Gastrointestinal Surg, POB 340, Helsinki 00029, Finland.
EM panu.mentula@hus.fi
RI Mentula, Panu/H-9025-2019
OI Mentula, Panu/0000-0002-6516-3797
CR Abbott DE, 2007, AM SURGEON, V73, P1224
   An G, 2008, CRIT CARE MED, V36, P1304, DOI 10.1097/CCM.0b013e31816929f4
   Attard JAP, 2005, DIS COLON RECTUM, V48, P1460, DOI 10.1007/s10350-005-0047-3
   Balogh Z, 2003, J TRAUMA, V54, P848, DOI 10.1097/01.TA.0000070166.29649.F3
   Balogh Z, 2003, SHOCK, V20, P483, DOI 10.1097/01.shk.0000093346.68755.43
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Basu A, 2008, WORLD J SURG, V32, P1851, DOI 10.1007/s00268-008-9605-x
   Batacchi S, 2009, CRIT CARE, V13, DOI 10.1186/cc8193
   Becker HP, 2007, SCAND J SURG, V96, P263, DOI 10.1177/145749690709600402
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   Bellomo R, 2004, CRIT CARE, V8, pR204, DOI 10.1186/cc2872
   Bjorck M, 1997, EUR J VASC ENDOVASC, V13, P531, DOI 10.1016/S1078-5884(97)80061-5
   Björck M, 2002, BRIT J SURG, V89, P923, DOI 10.1046/j.1365-2168.2002.02150.x
   Björck M, 2009, WORLD J SURG, V33, P1154, DOI 10.1007/s00268-009-9996-3
   BONGARD F, 1995, J TRAUMA, V39, P519
   Byrnes MC, 2010, AM J SURG, V199, P359, DOI 10.1016/j.amjsurg.2009.08.033
   Cheatham ML, 2007, INTENS CARE MED, V33, P951, DOI 10.1007/s00134-007-0592-4
   Cheatham ML, 2010, CRIT CARE MED, V38, P402, DOI 10.1097/CCM.0b013e3181b9e9b1
   Cheatham ML, 2000, J TRAUMA, V49, P621, DOI 10.1097/00005373-200010000-00008
   Chen H, 2008, WORLD J GASTROENTERO, V14, P3541, DOI 10.3748/wjg.14.3541
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   Dalfino L, 2008, INTENS CARE MED, V34, P707, DOI 10.1007/s00134-007-0969-4
   De Laet IE, 2008, LANGENBECK ARCH SURG, V393, P833, DOI 10.1007/s00423-008-0347-x
   De Waele JJ, 2006, CRIT CARE, V10, DOI 10.1186/cc4870
   De Waele JJ, 2009, WORLD J SURG, V33, P1128, DOI 10.1007/s00268-009-9994-5
   Djavani K, 2006, EUR J VASC ENDOVASC, V31, P581, DOI 10.1016/j.ejvs.2005.12.007
   Djavani K, 2009, BRIT J SURG, V96, P621, DOI 10.1002/bjs.6592
   Duttaroy DD, 2009, SURG INFECT, V10, P129, DOI 10.1089/sur.2007.030
   Edwards MS, 2003, ANN VASC SURG, V17, P72, DOI 10.1007/s10016-001-0329-8
   Fantus RJ, 2006, AM J SURG, V192, P243, DOI 10.1016/j.amjsurg.2005.11.013
   Fischer PE, 2009, J TRAUMA, V67, P924, DOI 10.1097/TA.0b013e3181ad5463
   Freeman AJ, 2005, ANZ J SURG, V75, P308, DOI 10.1111/j.1445-2197.2005.03373.x
   Hadeed JG, 2007, AM SURGEON, V73, P10
   IBERTI TJ, 1989, ANESTHESIOLOGY, V70, P47, DOI 10.1097/00000542-198901000-00011
   Ivatury R, 2009, WORLD J SURG, V33, P1150, DOI 10.1007/s00268-009-0005-7
   Ivatury RR, 2000, J TRAUMA, V49, P626
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   Kirshtein B, 2007, AM SURGEON, V73, P249
   Kubiak BD, 2010, SHOCK, V34, P525, DOI 10.1097/SHK.0b013e3181e14cd2
   Leppäniemi AK, 2010, CRIT CARE, V14, DOI 10.1186/cc8857
   Maas SM, 2002, J AM COLL SURGEONS, V194, P388, DOI 10.1016/S1072-7515(01)01140-1
   Malbrain MLNG, 2008, CRIT CARE MED, V36, P1972, DOI 10.1097/CCM.0b013e318176ab25
   Malbrain MLNG, 2005, CRIT CARE MED, V33, P315, DOI 10.1097/01.CCM.0000153408.09806.1B
   Matheson PJ, 2009, ARCH SURG-CHICAGO, V144, P625, DOI 10.1001/archsurg.2009.125
   McNelis J, 2002, AM SURGEON, V68, P18
   Mentula P, 2010, ARCH SURG-CHICAGO, V145, P764, DOI 10.1001/archsurg.2010.132
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   Petersson U, 2007, WORLD J SURG, V31, P2133, DOI 10.1007/s00268-007-9222-0
   Pieracci FM, 2007, SCAND J SURG, V96, P184, DOI 10.1177/145749690709600302
   Pliakos I, 2010, SURGERY, V148, P947, DOI 10.1016/j.surg.2010.01.021
   Poulakidas S, 2009, J TRAUMA, V67, P1435, DOI 10.1097/TA.0b013e3181b5f346
   RAMIREZ OM, 1990, PLAST RECONSTR SURG, V86, P519, DOI 10.1097/00006534-199009000-00023
   Rezende-Neto JB, 2003, SHOCK, V20, P303, DOI 10.1097/01.shk.0000082487.34705.d3
   Rezende-Neto JB, 2002, J TRAUMA, V53, P1121, DOI 10.1097/00005373-200212000-00015
   Riché FC, 2009, CRIT CARE, V13, DOI 10.1186/cc7931
   Rosen M J, 2007, Hernia, V11, P435, DOI 10.1007/s10029-007-0255-y
   ROTONDO MF, 1993, J TRAUMA, V35, P375, DOI 10.1097/00005373-199309000-00008
   SCHEIN M, 1986, SURG GYNECOL OBSTET, V163, P587
   Smith JW, 2010, J AM COLL SURGEONS, V210, P658, DOI 10.1016/j.jamcollsurg.2010.01.014
   Sorensen LT, 2005, ANN SURG, V241, P654, DOI 10.1097/01.sla.0000157131.84130.12
   Subramonia S, 2009, WORLD J SURG, V33, P931, DOI 10.1007/s00268-009-9947-z
   Sugrue M, 1999, ARCH SURG-CHICAGO, V134, P1082, DOI 10.1001/archsurg.134.10.1082
   Sugrue M, 1998, J TRAUMA, V45, P914, DOI 10.1097/00005373-199811000-00013
   Tieu BH, 2008, J TRAUMA, V65, P865, DOI 10.1097/TA.0b013e31818481f1
   Tsuei BJ, 2004, AM SURGEON, V70, P652
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   Vertrees A, 2008, J AM COLL SURGEONS, V207, P801, DOI 10.1016/j.jamcollsurg.2008.08.014
   Vidal MG, 2008, CRIT CARE MED, V36, P1823, DOI 10.1097/CCM.0b013e31817c7a4d
   WITTMANN DH, 1993, EUR J SURG, V159, P75
NR 70
TC 10
Z9 10
U1 0
U2 5
PU EDIZIONI MINERVA MEDICA
PI TURIN
PA CORSO BRAMANTE 83-85 INT JOURNALS DEPT., 10126 TURIN, ITALY
SN 0026-4733
EI 1827-1626
J9 MINERVA CHIR
JI Minerva Chir.
PD APR
PY 2011
VL 66
IS 2
BP 153
EP 163
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 774TR
UT WOS:000291410000010
PM 21593717
DA 2026-07-24
ER

PT J
AU Rozen, WM
   Shahbaz, S
   Morsi, A
AF Rozen, Warren Matthew
   Shahbaz, Shekhib
   Morsi, Adel
TI An improved alternative to vacuum-assisted closure (VAC) as a negative
   pressure dressing in lower limb split skin grafting: A clinical trial
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article
DE split; skin; graft; negative; pressure; dressings
ID BOLSTER
AB Background: The use of negative pressure in the dressing of split skin grafts has been shown to promote heating by a variety of mechanisms, including a decrease in interstitial oedema, an increase in perfusion and a decrease in bacterial. colonisation. Vacuum-assisted closure (VAC) dressings have, until now, been used as the archetype for negative pressure dressings and have been reflected as such in the literature. However, patient mobility and cost are still an issue with these dressings, and alternatives have been keenly sought. We describe an alternative method of negative pressure dressing, which we have found to be a safe and successful alternative in the setting of tower limb split skin grafts.
   Materials and methods: A prospective cohort investigation was performed on nine consecutive patients at Monash Medical Centre undergoing split-skin grafting for a Lower limb soft tissue defect. The dressing comprised a single cut foam sheet, a conventional disposable closed-system suction drain and an adhesive dressing.
   Results: In all nine patients, there was a 100% take of the graft, with no partial or complete loss. There were no complications encountered. Cost analysis demonstrated a minimum treatment cost of $577 over 5 days compared to $3180 for commercial VAC dressed wounds: a net saving of $2603 per patient.
   Conclusions: The use of a simple suction drain is a cheap and safe alternative to commercial VAC dressings for the treatment of Lower limb split skin grafts. Length of hospital stay and cost are superior to VAC, with no diminished clinical outcome. (c) 2007 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. ALL rights reserved.
C1 [Rozen, Warren Matthew; Shahbaz, Shekhib; Morsi, Adel] Royal Melbourne Hosp, Dept Surg, Parkville, Vic, Australia.
C3 Melbourne Health; Royal Melbourne Hospital
RP Rozen, WM (通讯作者)，Royal Melbourne Hosp, Dept Surg, 32A Wanda Rd, N Caulfield, Vic 3161, Australia.
EM warrenrozen@hotmail.com
RI Rozen, Warren Matthew/AAE-6296-2022
OI Rozen, Warren Matthew/0000-0002-4092-182X; Morsi,
   Adel/0000-0002-4298-0989
CR Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Collier M, 1997, Nurs Times, V93, P32
   Deva AK, 2000, MED J AUSTRALIA, V173, P128, DOI 10.5694/j.1326-5377.2000.tb125564.x
   Moisidis E, 2004, PLAST RECONSTR SURG, V114, P917, DOI 10.1097/01.PRS.0000133168.57199.E1
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Philbeck T E Jr, 1999, Ostomy Wound Manage, V45, P41
   Plikaitis CM, 2006, EXPERT REV MED DEVIC, V3, P175, DOI 10.1586/17434440.3.2.175
   Smahel J, 1977, Clin Plast Surg, V4, P409
   Vidrine DM, 2005, OTOLARYNG HEAD NECK, V133, P403, DOI 10.1016/j.otohns.2005.04.028
NR 9
TC 25
Z9 32
U1 0
U2 2
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PY 2008
VL 61
IS 3
BP 334
EP 337
DI 10.1016/j.bjps.2007.01.064
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 278FI
UT WOS:000254269600019
PM 18267313
DA 2026-07-24
ER

PT J
AU Bao, TZ
   Han, F
   Xu, F
   Yang, Y
   Shu, X
   Chen, K
   Qi, BW
   Wei, SJ
   Yu, AX
AF Bao, Tongzhu
   Han, Fang
   Xu, Feng
   Yang, Yi
   Shu, Xun
   Chen, Ken
   Qi, Baiwen
   Wei, Shijun
   Yu, Aixi
TI Papineau technique combined with vacuum-assisted closure for open tibial
   fractures: clinical outcomes at five years
SO INTERNATIONAL ORTHOPAEDICS
LA English
DT Article
DE Bone graft; Open fracture; Papineau technique; Segmental bone defect;
   Tibia fracture; Vacuum-assisted closure
ID PRESSURE WOUND THERAPY; EVIDENCE-BASED RECOMMENDATIONS; LOWER-EXTREMITY;
   BONE TRANSPORT; POSTTRAUMATIC OSTEOMYELITIS; INTERNATIONAL CONSENSUS;
   LIMB SALVAGE; RECONSTRUCTION; MANAGEMENT; NONUNIONS
AB Purpose Treatment of open tibial fractures with soft tissue and segmental bone defects is difficult. This study reports our results for treating these injuries with a combination of Papineau open bone grafting and vacuum-assisted wound closure (VAC).
   Methods The records of 19 patients with open tibial fractures with soft tissue and segmental bone defects treated with bone grafting and VAC from 2004 to 2010 were retrospectively reviewed. Outcomes included: time to complete granulation tissue coverage, wound healing, and bone union; length of hospitalization; frequency of debridement; number of deep tissue infections.
   Results Initial surgery was performed within 48 hours of injury. Ten fractures were Orthopaedic Trauma Association classification 41-A3, one was 41-C3, seven were 43-A3, and one was 43-C3. No surgical complications occurred, and the mean length of hospitalization was 11.0 +/- 3.0 weeks (range, 7-18 weeks). The mean follow-up time was 59.35 +/- 8.76 months. The mean time for complete wound healing was 7.76 +/- 1.52 weeks (range, 6-11 weeks). Bone union was achieved in all patients at a mean of 33.88 +/- 8.37 weeks (range, 23-53 weeks). Only one patient developed a deep tissue infection, which was treated with antibiotics and debridements, and complete bone union wound healing was achieved. Based on Paley grade, five outcomes were excellent, eight were good, and four were fair.
   Conclusions The combination of VAC and open bone grafting results in good outcome for patients with open tibial fractures and severe bone and soft-tissue defects.
C1 [Bao, Tongzhu; Yang, Yi; Shu, Xun; Chen, Ken] China Three Gorges Univ, Dept Orthoped, Yichang Cent Peoples Hosp, Yichang 443002, Peoples R China.
   [Bao, Tongzhu; Yang, Yi; Shu, Xun; Chen, Ken] China Three Gorges Univ, Affiliated Hosp 1, Yichang 443002, Peoples R China.
   [Han, Fang; Xu, Feng; Wei, Shijun] Wuhan Gen Hosp, Dept Orthoped, Hongshan Area, 627 Wuluo Rd, Wuhan 430070, Hubei, Peoples R China.
   [Qi, Baiwen; Yu, Aixi] Wuhan Univ, Dept Microsurg, Zhongnan Hosp, Wuhan 430071, Hubei, Peoples R China.
C3 China Three Gorges University; China Three Gorges University; Wuhan
   University
RP Wei, SJ (通讯作者)，Wuhan Gen Hosp, Dept Orthoped, Hongshan Area, 627 Wuluo Rd, Wuhan 430070, Hubei, Peoples R China.; Yu, AX (通讯作者)，Wuhan Univ, Dept Microsurg, Zhongnan Hosp, Wuhan 430071, Hubei, Peoples R China.
EM wsj1974@yeah.net; yuaixi666@163.com
RI Yang, Yi/MIU-4567-2025
OI Shijun, Wei/0000-0001-5105-0196
FU National Natural Science Foundation of China [81572163]; Wuhan
   Cultivation Program for Middle-aged and Young Medical Talents [2014-77]
FX This study is supported by the National Natural Science Foundation of
   China (General Program) [Grant No. 81572163] and the Wuhan Cultivation
   Program for Middle-aged and Young Medical Talents [Grant No. 2014-77].
CR Archdeacon MT, 2006, J ORTHOP TRAUMA, V20, P134, DOI 10.1097/01.bot.0000184147.82824.7c
   Asomugha EU, 2014, TECH FOOT ANKLE SURG, V13, P108, DOI 10.1097/BTF.0000000000000033
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   Bucalo Brian, 1993, Wound Repair and Regeneration, V1, P181, DOI 10.1046/j.1524-475X.1993.10308.x
   Busse JW, 2007, J ORTHOP TRAUMA, V21, P70, DOI 10.1097/BOT.0b013e31802cbc43
   Dedmond BT, 2007, J ORTHOP TRAUMA, V21, P11, DOI 10.1097/BOT.0b013e31802cbc54
   Deng ZM, 2014, ARCH MED SCI, V10, P764, DOI 10.5114/aoms.2013.34411
   Gonzalez A, 2014, INT ORTHOP, V38, P2323, DOI 10.1007/s00264-014-2395-x
   Hak DJ, 2014, INJURY, V45, pS3, DOI 10.1016/j.injury.2014.04.002
   Karargyris Orestis, 2014, Eur J Orthop Surg Traumatol, V24, P1013, DOI 10.1007/s00590-013-1279-x
   Koettstorfer J, 2012, ARCH ORTHOP TRAUM SU, V132, P1399, DOI 10.1007/s00402-012-1564-x
   Lei H, 1998, J Orthop Sci, V3, P318
   Matos MA, 2015, J ORTHOP TRAUMATOL, V16, P195, DOI 10.1007/s10195-015-0345-z
   Obremskey W, 2014, J ORTHOP TRAUMA, V28, pE203, DOI 10.1097/BOT.0000000000000034
   PALEY D, 1989, CLIN ORTHOP RELAT R, P146
   Panda M, 1998, INT ORTHOP, V22, P37, DOI 10.1007/s002640050204
   PAPINEAU LJ, 1973, NOUV PRESSE MED, V2, P2753
   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
   Sadek AF, 2016, ARCH ORTHOP TRAUM SU, V136, P1233, DOI 10.1007/s00402-016-2523-8
   Schlatterer DR, 2015, CLIN ORTHOP RELAT R, V473, P1802, DOI 10.1007/s11999-015-4140-1
   Smith WR, 2007, INT ORTHOP, V31, P165, DOI 10.1007/s00264-006-0172-1
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Tan Y, 2011, ARCH ORTHOP TRAUM SU, V131, P255, DOI 10.1007/s00402-010-1197-x
   Tong K, 2017, INJURY, V48, P1616, DOI 10.1016/j.injury.2017.03.042
   Tulner SAF, 2004, J TRAUMA, V56, P633, DOI 10.1097/01.TA.0000112327.50235.0A
   Vig S, 2011, J TISSUE VIABILITY, V20, pS1, DOI 10.1016/j.jtv.2011.07.002
   Whelan DB, 2002, J BONE JOINT SURG BR, V84B, P15, DOI 10.1302/0301-620X.84B1.11347
   Yazar S, 2004, PLAST RECONSTR SURG, V114, P1457, DOI 10.1097/01.PRS.0000138811.88807.65
NR 28
TC 17
Z9 20
U1 0
U2 7
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0341-2695
EI 1432-5195
J9 INT ORTHOP
JI Int. Orthop.
PD NOV
PY 2017
VL 41
IS 11
BP 2389
EP 2396
DI 10.1007/s00264-017-3620-1
PG 8
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA FJ5BA
UT WOS:000412757900024
PM 28849424
DA 2026-07-24
ER

PT J
AU Ozer, MT
   Coskun, AK
   Ozerhan, IH
   Ersoz, N
   Yildiz, R
   Sinan, H
   Demirbas, S
   Kozak, O
   Uzar, AI
   Cetiner, S
AF Ozer, Mustafa Tahir
   Coskun, Ali Kagan
   Ozerhan, Ismail Hakki
   Ersoz, Nail
   Yildiz, Ramazan
   Sinan, Huseyin
   Demirbas, Sezai
   Kozak, Orhan
   Uzar, Ali Ihsan
   Cetiner, Sadettin
TI Use of vacuum-assisted closure (VAC™) in high-energy complicated
   perineal injuries: analysis of nine cases
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE High-energy perineal trauma; Vacuum-assisted closure; Wound care
ID OPEN PELVIC FRACTURES; SOFT-TISSUE INJURIES; WOUND CONTROL; MANAGEMENT;
   THERAPY; TRAUMA
AB Our study reviewed nine patients who were treated with the VAC (TM) Abdominal Dressing System after suffering pelvic fractures and soft tissue loss after high-energy pelvic trauma. Between March 2008 and August 2009, our clinic treated nine patients with complicated perineal injuries from high-energy pelvic trauma with multiple irrigation and debridement procedures and broad-spectrum antibiotics. Protective ostomies were created for all nine patients. Required interventions were made for associated injuries, and VAC (TM) application was started. All patients were male, with an average age of 24.3 (range 21-32) years, and a mean injury severity score of 36.4 (range 16-59). Wound diameters ranged from 15 to 30 cm, and wound depths ranged from 5 to 25 cm. The injuries included one traumatic bilateral hemipelvectomy, and three unilateral and two bilateral lower extremity amputations. Intensive care unit length of stay averaged 12 (6-19) days, and average hospital length of stay was 44.12 (31-64) days. Beginning at an average of day 17 (+/- 5.9 days) post-injury, wound cultures detected no bacterial colonisation. One patient died on the sixth day after injury from septic complications. Two patients' wounds were closed by primary closure, and six patients' wounds were closed by split thickness grafts after an average of 31.4 (17-50) days. Optimal treatment of high-energy perineal injuries requires early and extensive debridement and rich irrigation. The application of the VAC (TM) system as temporary coverage of large complex wounds in the pelvic region enhances wound healing and facilitates an early grafting process.
C1 [Ozer, Mustafa Tahir; Coskun, Ali Kagan; Ozerhan, Ismail Hakki; Ersoz, Nail; Yildiz, Ramazan; Sinan, Huseyin; Demirbas, Sezai; Kozak, Orhan; Uzar, Ali Ihsan; Cetiner, Sadettin] Gulhane Mil Med Acad, Dept Gen Surg, TR-06018 Ankara, Etlik, Turkey.
C3 Gulhane Training & Research Hospital
RP Sinan, H (通讯作者)，Gulhane Mil Med Acad, Dept Gen Surg, TR-06018 Ankara, Etlik, Turkey.
EM hsinan@gata.edu.tr
RI /J-2289-2015; OZERHAN, ISMAIL HAKKI/H-8689-2012; /ACE-3488-2022;
   /O-2379-2014; yıldız, ramazan/HFZ-9568-2022; özerhan, ismail
   hakkı/H-8689-2012
OI OZERHAN, ISMAIL HAKKI/0000-0001-7142-9793; UZAR, Ali
   İhsan/0000-0003-0889-1496; Kozak, Orhan/0000-0002-7302-1203; özerhan,
   ismail hakkı/0000-0001-5777-8671
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bronchard R, 2008, INTENS CARE MED, V34, P1345, DOI 10.1007/s00134-008-1094-8
   Demir A., 2006, TURK PLAST REKONSTR, V14, P171
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Giannoudis PV, 2004, INJURY, V35, P671, DOI 10.1016/j.injury.2004.03.003
   Hak DJ, 1997, J TRAUMA, V42, P1046, DOI 10.1097/00005373-199706000-00010
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Jeffery LC, 2009, EPLASTY, V9, pe28
   Jones AL, 1997, ORTHOP CLIN N AM, V28, P345, DOI 10.1016/S0030-5898(05)70293-5
   Labler L, 2002, Swiss Surg, V8, P266, DOI 10.1024/1023-9332.8.6.266
   Labler L., 2004, Eur J Trauma, V30, P305, DOI 10.1007/s00068-004-1389-6
   Labler L, 2007, LANGENBECK ARCH SURG, V392, P601, DOI 10.1007/s00423-006-0090-0
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Ozturk E, 2009, AM J SURG, V197, P660, DOI 10.1016/j.amjsurg.2008.04.018
   Pell M, 1998, J TRAUMA, V45, P371, DOI 10.1097/00005373-199808000-00029
   Simsek A, 2007, BMMR, V10, P136
   SMEKTALA R, 1995, ZBL CHIR, V120, P893
   Stuhmiller J.H., 1991, PHYS MECH PRIMARY BL, p241 270
   Wightman JM, 2001, ANN EMERG MED, V37, P664, DOI 10.1067/mem.2001.114906
   Woods RK, 1998, ARCH SURG-CHICAGO, V133, P281, DOI 10.1001/archsurg.133.3.281
NR 21
TC 9
Z9 21
U1 0
U2 11
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1742-4801
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2011
VL 8
IS 6
BP 599
EP 607
DI 10.1111/j.1742-481X.2011.00835.x
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 854AL
UT WOS:000297466800006
PM 21854547
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Schiestl, C
   Neuhaus, K
   Biedermann, T
   Böttcher-Haberzeth, S
   Reichmann, E
   Meuli, M
AF Schiestl, C.
   Neuhaus, K.
   Biedermann, T.
   Boettcher-Haberzeth, S.
   Reichmann, E.
   Meuli, M.
TI Novel Treatment for Massive Lower Extremity Avulsion Injuries in
   Children: Slow, but Effective with Good Cosmesis
SO EUROPEAN JOURNAL OF PEDIATRIC SURGERY
LA English
DT Article
DE avulsion injury; vacuum assisted closure system; integra dermal
   regeneration template; reconstructive surgery; children
ID DEGLOVING INJURIES; MANAGEMENT; INTEGRA; WOUNDS; SKIN
AB Background: Extended avulsion injuries are associated with significant loss of skin and subcutaneous fat, leaving the reconstructive surgeon with the challenge of substituting all tissues lost in the best possible way. We wanted to test whether the combined use of a Vacuum Assisted Closure system (VAC) and Integra Dermal Regeneration Template (IDRT) matched the required treatment profile encompassing initial control of infection, remodeling of body contours, and reconstruction of near normal skin.
   Materials and Methods: 4 children with massive lower extremity avulsion injuries were treated with early necrosectomy, VAC application for 3-5 weeks for wound cleansing and wound bed conditioning, subsequent implantation of IDRT, and finally autologous split thickness skin grafting (STSG) for definitive wound closure. Thereafter, a standard rehabilitation program was used. The key parameters of VAC and IDRT application, take rates of IDRT and STSG, complications, length of stay, and final outcome were recorded.
   Results: In all patients, early removal of necrosis and infection control was successfully achieved. Continuous VAC application fostered the formation of a several millimeters thick new tissue layer partly compensating for the lost hypodermis. IDRT implantation and subsequent STSG yielded take rates of nearly 100% and both functionally and cosmetically excellent long-term results. There were no major complications.
   Conclusion: The combination of VAC and IDRT in children with massive leg avulsion injuries is feasible, safe, and delivers high-quality long-term outcomes that appear to justify the multiple operative procedures, the long hospitalization times, and the comparatively high costs entailed.
C1 [Schiestl, C.; Neuhaus, K.; Meuli, M.] Univ Childrens Hosp Zurich, Pediat Burn Ctr, Dept Surg, CH-8032 Zurich, Switzerland.
   [Biedermann, T.; Boettcher-Haberzeth, S.; Reichmann, E.] Dept Surg, Tissue Biol Res Unit, Zurich, Switzerland.
C3 University Children's Hospital Zurich
RP Schiestl, C (通讯作者)，Univ Childrens Hosp Zurich, Pediat Burn Ctr, Dept Surg, Steinwiesstr 75, CH-8032 Zurich, Switzerland.
EM clemens.schiestl@kispi.uzh.ch
RI ; Böttcher, Sophie/JBS-3818-2023
OI Neuhaus, Kathrin/0000-0003-2438-1779; Böttcher,
   Sophie/0000-0002-7713-9807
CR [Anonymous], J TRAUMA
   Bovill E, 2008, INT WOUND J, V5, P511, DOI 10.1111/j.1742-481X.2008.00437.x
   Cass DL, 1997, PEDIATR SURG INT, V12, P484, DOI 10.1007/s003830050189
   Corps B V, 1969, Br J Plast Surg, V22, P125, DOI 10.1016/S0007-1226(69)80053-6
   DIETRICH F, 1974, CHIR PLAST, V2, P143
   Helgeson MD, 2007, J ORTHOP TRAUMA, V21, P394, DOI 10.1097/BOT.0b013e318070c028
   HIDALGO DA, 1986, CLIN PLAST SURG, V13, P701
   Hierner R, 2009, UNFALLCHIRURG, V112, P55, DOI 10.1007/s00113-008-1548-z
   Jeng JC, 2007, J BURN CARE RES, V28, P120, DOI 10.1097/BCR.0b013E31802CB83F
   Kirkby KA, 2009, COMPENDIUM, V31, P568
   KUDSK KA, 1981, J TRAUMA, V21, P835, DOI 10.1097/00005373-198110000-00002
   MEULI M, 1992, EUR J PEDIATR SURG, V2, P195, DOI 10.1055/s-2008-1063439
   Mooney JF, 2000, CLIN ORTHOP RELAT R, P26
   Nguyen DQA, 2010, BURNS, V36, P23, DOI 10.1016/j.burns.2009.07.011
   Schiestl C, 2010, J PLAST RECONSTR AES, V63, P610, DOI 10.1016/j.bjps.2009.01.050
   Stiefel D, 2010, BURNS, V36, P114, DOI 10.1016/j.burns.2009.02.023
   Stiefel D, 2009, J PEDIATR SURG, V44, P575, DOI 10.1016/j.jpedsurg.2008.07.006
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Wolter TP, 2005, BRIT J PLAST SURG, V58, P416, DOI 10.1016/j.bjps.2004.04.008
NR 19
TC 30
Z9 33
U1 0
U2 3
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0939-7248
J9 EUR J PEDIATR SURG
JI Eur. J. Pediatr. Surg.
PD MAR
PY 2011
VL 21
IS 2
BP 106
EP 110
DI 10.1055/s-0030-1267234
PG 5
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA 750NL
UT WOS:000289554900008
PM 21157691
DA 2026-07-24
ER

PT J
AU Erba, P
   Ogawa, R
   Ackermann, M
   Adini, A
   Miele, LF
   Dastouri, P
   Helm, D
   Mentzer, SJ
   D'Amato, RJ
   Murphy, GF
   Konerding, MA
   Orgill, DP
AF Erba, Paolo
   Ogawa, Rei
   Ackermann, Maximilian
   Adini, Avner
   Miele, Lino F.
   Dastouri, Pouya
   Helm, Doug
   Mentzer, Steven J.
   D'Amato, Robert J.
   Murphy, George F.
   Konerding, Moritz A.
   Orgill, Dennis P.
TI Angiogenesis in Wounds Treated by Microdeformational Wound Therapy
SO ANNALS OF SURGERY
LA English
DT Article
ID ENDOTHELIAL GROWTH-FACTOR; VACUUM-ASSISTED CLOSURE; TOPICAL
   NEGATIVE-PRESSURE; FACTOR VEGF; IN-VITRO; EXPRESSION; HYPOXIA; OXYGEN;
   CANCER; TISSUE
AB Background: Mechanical forces play an important role in tissue neovascularization and are a constituent part of modern wound therapies. The mechanisms by which vacuum assisted closure (VAC) modulates wound angiogenesis are still largely unknown.
   Objective: To investigate how VAC treatment affects wound hypoxia and related profiles of angiogenic factors as well as to identify the anatomical characteristics of the resultant, newly formed vessels.
   Methods: Wound neovascularization was evaluated by morphometric analysis of CD31-stained wound cross-sections as well as by corrosion casting analysis. Wound hypoxia and mRNA expression of HIF-1 alpha and associated angiogenic factors were evaluated by pimonidazole hydrochloride staining and quantitative reverse transcription-polymerase chain reaction (RT-PCR), respectively. Vascular endothelial growth factor (VEGF) protein levels were determined by western blot analysis.
   Results: VAC-treated wounds were characterized by the formation of elongated vessels aligned in parallel and consistent with physiologically function, compared to occlusive dressing control wounds that showed formation of tortuous, disoriented vessels. Moreover, VAC-treated wounds displayed a well-oxygenated wound bed, with hypoxia limited to the direct proximity of the VAC-foam interface, where higher VEGF levels were found. By contrast, occlusive dressing control wounds showed generalized hypoxia, with associated accumulation of HIF-1 alpha and related angiogenic factors.
   Conclusions: The combination of established gradients of hypoxia and VEGF expression along with mechanical forces exerted by VAC therapy was associated with the formation of more physiological blood vessels compared to occlusive dressing control wounds. These morphological changes are likely a necessary condition for better wound healing.
C1 [Erba, Paolo] Univ Lausanne Hosp, Dept Plast Reconstruct & Aesthet Surg, CH-1011 Lausanne, Switzerland.
   [Erba, Paolo; Ogawa, Rei; Dastouri, Pouya; Helm, Doug; Orgill, Dennis P.] Harvard Univ, Brigham & Womens Hosp, Tissue Engn & Wound Healing Lab, Div Plast Surg,Med Sch, Boston, MA 02115 USA.
   [Ogawa, Rei] Nippon Med Sch, Dept Plast Reconstruct & Aesthet Surg, Tokyo 113, Japan.
   [Ackermann, Maximilian; Konerding, Moritz A.] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Inst Funct & Clin Anat, Mainz, Germany.
   [Adini, Avner; D'Amato, Robert J.] Harvard Univ, Dept Surg, Vasc Biol Program,Childrens Hosp Boston, Sch Med, Boston, MA 02115 USA.
   [Miele, Lino F.; Mentzer, Steven J.] Harvard Univ, Sch Med, Lab Adapt & Regenerat Biol, Dept Surg, Boston, MA 02115 USA.
   [Murphy, George F.] Harvard Univ, Sch Med, Dept Pathol, Brigham & Womens Hosp, Boston, MA 02115 USA.
C3 University of Lausanne; Centre Hospitalier Universitaire Vaudois (CHUV);
   Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard Medical School; Nippon Medical School;
   Johannes Gutenberg University of Mainz; Harvard University; Harvard
   Medical School; Harvard University Medical Affiliates; Boston Children's
   Hospital; Harvard University; Harvard Medical School; Harvard
   University; Harvard University Medical Affiliates; Brigham & Women's
   Hospital; Harvard Medical School
RP Erba, P (通讯作者)，Univ Lausanne Hosp, Dept Plast Reconstruct & Aesthet Surg, CH-1011 Lausanne, Switzerland.
EM erbapaolo@hotmail.com
RI Orgill, Dennis/H-7596-2019; Adini, Avner/AAD-6141-2022
OI Orgill, Dennis/0000-0002-8279-7310; 
FU Kinetics Concepts, Inc.; Department of Surgery at Brigham and Women's
   Hospital
FX Dr. Orgill is an expert witness for Akin, Gump, Strauss, Hauer and Feld,
   LLP that represents Kinetics Concepts, Inc. Dr. Orgill is a principal
   investigator for a research grant to Brigham and Women's Hospital funded
   by Kinetics Concepts, Inc.The study was funded by the Department of
   Surgery at Brigham and Women's Hospital.
CR [Anonymous], HYPERBARIC SURG PERI
   Arany Z, 2008, NATURE, V451, P1008, DOI 10.1038/nature06613
   Brem H, 2007, J CLIN INVEST, V117, P1219, DOI 10.1172/JCI32169
   Carmeliet P, 2000, NATURE, V407, P249, DOI 10.1038/35025220
   Chang H, 2003, CLIN SCI, V104, P421, DOI 10.1042/CS20020210
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Cloutier M, 2008, EXP LUNG RES, V34, P101, DOI 10.1080/01902140701884331
   Constant JS, 2000, WOUND REPAIR REGEN, V8, P353, DOI 10.1046/j.1524-475x.2000.00353.x
   Coussens LM, 2002, NATURE, V420, P860, DOI 10.1038/nature01322
   Elson DA, 2000, CANCER RES, V60, P6189
   Evans SM, 2006, J INVEST DERMATOL, V126, P2596, DOI 10.1038/sj.jid.5700451
   Ferrara N, 2003, NAT MED, V9, P669, DOI 10.1038/nm0603-669
   Folkman J, 2007, NAT REV DRUG DISCOV, V6, P273, DOI 10.1038/nrd2115
   Fong GH, 2008, ANGIOGENESIS, V11, P121, DOI 10.1007/s10456-008-9107-3
   Fong GH, 2009, J MOL MED-JMM, V87, P549, DOI 10.1007/s00109-009-0458-z
   Ford CN, 2002, ANN PLAS SURG, V49, P55, DOI 10.1097/00000637-200207000-00009
   Fukumura D, 2007, MICROVASC RES, V74, P72, DOI 10.1016/j.mvr.2007.05.003
   Gerhardt H, 2003, J CELL BIOL, V161, P1163, DOI 10.1083/jcb.200302047
   Gordillo GM, 2003, AM J SURG, V186, P259, DOI 10.1016/S0002-9610(03)00211-3
   Gouttefangeas C, 2001, CLIN EXP IMMUNOL, V124, P398, DOI 10.1046/j.1365-2249.2001.01547.x
   Greenberg JI, 2008, NATURE, V456, P809, DOI 10.1038/nature07424
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   GREENHALGH DG, 1990, AM J PATHOL, V136, P1235
   Greif R, 2000, NEW ENGL J MED, V342, P161, DOI 10.1056/NEJM200001203420303
   Grimm A, 2007, STRAHLENTHER ONKOL, V183, P144, DOI 10.1007/s00066-007-1560-1
   Haroon ZA, 2000, ANN SURG, V231, P137, DOI 10.1097/00000658-200001000-00020
   Helm CLE, 2005, P NATL ACAD SCI USA, V102, P15779, DOI 10.1073/pnas.0503681102
   Huang LE, 1998, P NATL ACAD SCI USA, V95, P7987, DOI 10.1073/pnas.95.14.7987
   Jinnin M, 2008, NAT MED, V14, P1236, DOI 10.1038/nm.1877
   Kilarski WW, 2009, NAT MED, V15, P657, DOI 10.1038/nm.1985
   KNIGHTON DR, 1981, SURGERY, V90, P262
   KNIGHTON DR, 1983, SCIENCE, V221, P1283, DOI 10.1126/science.6612342
   Kodelja V, 1997, IMMUNOBIOLOGY, V197, P478, DOI 10.1016/S0171-2985(97)80080-0
   Labanaris AP, 2009, J PLAST RECONSTR AES, V62, P1068, DOI 10.1016/j.bjps.2008.01.006
   Labler L, 2009, J TRAUMA, V66, P749, DOI 10.1097/TA.0b013e318171971a
   Li J, 1997, J CLIN INVEST, V100, P18, DOI 10.1172/JCI119510
   MALKUSCH W, 1995, ANAL CELL PATHOL, V9, P69
   Mammoto A, 2009, NATURE, V457, P1103, DOI 10.1038/nature07765
   Mantovani A, 2008, NATURE, V454, P436, DOI 10.1038/nature07205
   MCNULTY A, 2007, WOUND REPAIR REGEN, V15, pA41
   Morbidelli L, 1997, Angiogenesis, V1, P117, DOI 10.1023/A:1018361217467
   Mouës CM, 2008, WOUND REPAIR REGEN, V16, P488, DOI 10.1111/j.1524-475X.2008.00395.x
   Murdoch C, 2004, BLOOD, V104, P2224, DOI 10.1182/blood-2004-03-1109
   Naumov GN, 2009, CLIN EXP METASTAS, V26, P51, DOI 10.1007/s10585-008-9176-0
   Nissen NN, 1998, AM J PATHOL, V152, P1445
   O'Toole EA, 1997, J CLIN INVEST, V100, P2881, DOI 10.1172/JCI119837
   Oberringer M, 2008, J MOL HISTOL, V39, P37, DOI 10.1007/s10735-007-9124-3
   Petersen W, 2004, J ORTHOP RES, V22, P847, DOI 10.1016/j.orthres.2003.11.009
   POTGENS AJG, 1994, J BIOL CHEM, V269, P32879
   Pugh CW, 2003, NAT MED, V9, P677, DOI 10.1038/nm0603-677
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Seko Y, 1999, BIOCHEM BIOPH RES CO, V254, P462, DOI 10.1006/bbrc.1998.9969
   Sen CK, 2002, J BIOL CHEM, V277, P33284, DOI 10.1074/jbc.M203391200
   Sessa C, 2008, NAT CLIN PRACT ONCOL, V5, P378, DOI 10.1038/ncponc1150
   Stockmann C, 2008, NATURE, V456, P814, DOI 10.1038/nature07445
   Takahashi Y, 2000, J BIOL CHEM, V275, P14139, DOI 10.1074/jbc.275.19.14139
   WEIBEL ER, 1966, J CELL BIOL, V30, P23, DOI 10.1083/jcb.30.1.23
   Willett CG, 2004, NAT MED, V10, P145, DOI 10.1038/nm988
   YANNAS IV, 1981, T AM SOC ART INT ORG, V27, P19
   Zhong H, 1999, BIOCHEM BIOPH RES CO, V259, P523, DOI 10.1006/bbrc.1999.0815
   Zhou J, 2006, CANCER LETT, V237, P10, DOI 10.1016/j.canlet.2005.05.028
NR 61
TC 160
Z9 197
U1 0
U2 23
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0003-4932
EI 1528-1140
J9 ANN SURG
JI Ann. Surg.
PD FEB
PY 2011
VL 253
IS 2
BP 402
EP 409
DI 10.1097/SLA.0b013e31820563a8
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 708OV
UT WOS:000286374400032
PM 21217515
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Öner, S
   Bekyürek, U
   Öner, BA
   Üre, I
   Yenilmez, A
AF Oner, Suleyman
   Bekyurek, Utku
   Oner, Betul Altintas
   Ure, Iyimser
   Yenilmez, Aydin
TI Evaluation of the Role of VAC in the Treatment of Fournier's Gangrene
SO ANZ JOURNAL OF SURGERY
LA English
DT Article; Early Access
DE andrology; Fournier's gangrene; infectious disease; surgical
   debridement; VAC
ID ASSISTED CLOSURE; MANAGEMENT; THERAPY
AB Objective: Standard treatment for Fournier's gangrene (FG) includes hemodynamic stabilization, aggressive surgical debridement, and broad-spectrum antibiotics. However, prolonged hospitalizations and multiple debridements increase costs and reduce productivity. This study compares vacuum-assisted closure (VAC) therapy with open wound dressing (OWD) in post-debridement management of FG. Materials and methods: Data of 60 patients diagnosed with FG and treated in our clinic were retrospectively analyzed. Data collected included demographic characteristics, comorbid systemic diseases, presence of sepsis at initial presentation, the origin of the gangrene (urogenital or perianal), FGSI, the need for additional surgical interventions during debridement (such as orchiectomy, penectomy, or colostomy), the type of wound dressing used (open wound dressing [OWD] or vacuum-assisted closure [VAC]), the number of debridement sessions, length of hospital stay, the requirement for grafting during wound closure, and mortality outcomes. These variables were analyzed based on hospital records. Results: VAC therapy was applied to 30 patients (50%). The mean age of patients in the VAC group was 63.1 +/- 11.7 years, compared to 65.2 +/- 12.1 years in the OWD group. The VAC group had a significantly shorter average hospital stay (15.17 +/- 9.19 days) than the OWD group (22.8 +/- 14.76 days) (p = 0.019). Additionally, the mean number of debridement sessions was significantly lower in the VAC group (3.27 +/- 2.15) compared to the OWD group (4.87 +/- 3.17) (p = 0.026). Conclusion: VAC therapy is an effective method for FG management, reducing debridement sessions and hospital stay compared to OWD.
C1 [Oner, Suleyman; Bekyurek, Utku; Ure, Iyimser; Yenilmez, Aydin] Eskisehir Osmangazi Univ, Fac Med, Dept Urol, Eskisehir, Turkiye.
   [Oner, Betul Altintas] Eskisehir City Hosp, Dept Infect Dis & Clin Microbiol, Eskisehir, Turkiye.
C3 Eskisehir Osmangazi University
RP Öner, S (通讯作者)，Eskisehir Osmangazi Univ, Fac Med, Dept Urol, Eskisehir, Turkiye.
EM drsuleymanoner@gmail.com
OI Bekyürek, Utku/0009-0003-9589-0949
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
   Akcan A, 2009, ULUS TRAVMA ACIL CER, V15, P342
   Assenza M, 2011, CLIN TER, V162, pE1
   Basoglu M, 2007, SURG TODAY, V37, P558, DOI 10.1007/s00595-006-3391-6
   Bonkat G., 2018, UROLOGICAL INFECT
   Bowen D, 2022, WORLD J UROL, V40, P2399, DOI 10.1007/s00345-022-04139-4
   Chawla SN, 2003, EUR UROL, V43, P572, DOI 10.1016/S0302-2838(03)00102-7
   Corman JM, 1999, BJU INT, V84, P85
   Cuccia G, 2009, UROL INT, V82, P426, DOI 10.1159/000218532
   Czymek R, 2009, AM J SURG, V197, P168, DOI 10.1016/j.amjsurg.2008.07.053
   Eke N, 2000, BJS-BRIT J SURG, V87, P718, DOI 10.1046/j.1365-2168.2000.01497.x
   Fournier J. A., 1883, SEMAINE MEDICALE, V4, P69
   Franco-Buenaventura D, 2021, INT UROL NEPHROL, V53, P641, DOI 10.1007/s11255-020-02705-6
   Gadler T, 2019, ADV EMERG NURS J, V41, P33, DOI 10.1097/TME.0000000000000221
   Gul MO, 2021, NIGER J CLIN PRACT, V24, P1277, DOI 10.4103/njcp.njcp_387_20
   Jallali N, 2005, AM J SURG, V189, P462, DOI 10.1016/j.amjsurg.2005.01.012
   Karian Laurel S, 2015, Eplasty, V15, pe18
   Katusic J, 2010, ACTA CLIN CROAT, V49, P453
   Korkut M, 2003, DIS COLON RECTUM, V46, P649, DOI 10.1007/s10350-004-6626-x
   Lin TY, 2014, INT J UROL, V21, P696, DOI 10.1111/iju.12426
   Montrief T, 2019, J EMERG MED, V57, P488, DOI 10.1016/j.jemermed.2019.06.023
   Morpurgo E, 2002, SURG CLIN N AM, V82, P1213, DOI 10.1016/S0039-6109(02)00058-0
   PATY R, 1992, UROL CLIN N AM, V19, P149
   Singer M, 2016, JAMA-J AM MED ASSOC, V315, P801, DOI 10.1001/jama.2016.0287
   Tang LM, 2015, SPRINGERPLUS, V4, DOI 10.1186/s40064-014-0783-8
   Unal B, 2006, SAUDI MED J, V27, P1038
   Yaghan RJ, 2000, DIS COLON RECTUM, V43, P1300, DOI 10.1007/BF02237442
   Yanar H, 2006, WORLD J SURG, V30, P1750, DOI 10.1007/s00268-005-0777-3
   Yanaral F, 2017, ARCH ITAL UROL ANDRO, V89, P208, DOI 10.4081/aiua.2017.3.208
   Yilmazlar T, 2014, ULUS TRAVMA ACIL CER, V20, P333, DOI 10.5505/tjtes.2014.06870
   Yücel M, 2017, ULUS TRAVMA ACIL CER, V23, P400, DOI 10.5505/tjtes.2017.01678
   Zhang N, 2020, BMC SURG, V20, DOI 10.1186/s12893-020-00916-3
NR 32
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1445-1433
EI 1445-2197
J9 ANZ J SURG
JI ANZ J. Surg.
PD 2026 APR 30
PY 2026
DI 10.1111/ans.70712
EA APR 2026
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HI0CQ
UT WOS:001754514500001
PM 42059775
DA 2026-07-24
ER

PT J
AU Pepe, G
   Magalini, S
   Callari, C
   Persiani, R
   Lodoli, C
   Gui, D
AF Pepe, G.
   Magalini, S.
   Callari, C.
   Persiani, R.
   Lodoli, C.
   Gui, D.
TI Vacuum Assisted Closure (VAC) therapy™ as a swiss knife multi-tool for
   enteric fistula closure: tips and tricks: a pilot study
SO EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
LA English
DT Article
DE Enterocutaneous fistula management; VAC therapy (TM)
ID ENTEROCUTANEOUS FISTULAS; OPEN ABDOMEN; NEGATIVE-PRESSURE; MANAGEMENT;
   METAANALYSIS; WOUNDS; SYSTEM
AB OBJECTIVE: Enterocutaneous fistulas (ECFs) are an uncommon surgical problem, but they are characterized by a difficult management. Vacuum-assisted closure (VAC) therapy is a method utilized for chronic and traumatic wound healing. At first, VAC therapy had been contraindicated in the treatment of intestinal fistulas, but as time went by, VAC therapy revealed itself to be a "Swiss knife multi-tool". This paper presents some clinical cases of enterocutaneous (ECF) and enteroatmospheric fistulas (EAF) treated with VAC therapy T.
   MATERIALS AND METHODS: The history of 8 patients treated for complex fistulas was revised. Four of them presented with enterocutaneous and four with enteroatmospheric fistulas. All were treated with VAC therapy with variations elaborated to help in accelerated closure of intestinal wall lesions.
   RESULTS: Four out of four ECFs closed spontaneously. In the EAF group, in three cases the fistula turned slowly into an entero-cutaneous fistula, and in one out of four it closed spontaneously. The mean length of VAC therapy T was 35.5 days and that of spontaneous closure was 36.4 days.
   CONCLUSIONS: The results of our study encourage the use of VAC therapy T for the treatment of enterocutaneous fistulas. VAC therapy T use has a double therapeutic value: (1) it promotes the healing of the skin and allows also the management of EAFs; (2) in selected cases, those in which it is possible to create a deep fistula tract ("well") it is possible to assist to a complete healing with closure of the ECFs.
C1 [Pepe, G.; Magalini, S.; Lodoli, C.; Gui, D.] Univ Cattolica Sacro Cuore, Gemelli Polyclin, Dept Surg, Emergency Surg Unit, I-00168 Rome, Italy.
   [Callari, C.] Univ Cattolica Sacro Cuore, Gemelli Polyclin, Dept Surg, Endocrine & Metab Surg Unit, I-00168 Rome, Italy.
   [Persiani, R.] Univ Cattolica Sacro Cuore, Gemelli Polyclin, Dept Surg, Gen Surg Unit, I-00168 Rome, Italy.
C3 Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli;
   Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli;
   Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli
RP Pepe, G (通讯作者)，Univ Cattolica Sacro Cuore, Gemelli Polyclin, Dept Surg, Emergency Surg Unit, I-00168 Rome, Italy.
EM gildapepe@yahoo.it
RI Persiani, Roberto/AAC-2077-2022
OI Persiani, Roberto/0000-0001-5584-6095
CR [Anonymous], WORLD J SURG ONCOL
   Banasiewicz T, 2011, VIDEOSURGERY MINIINV, V6, P155, DOI 10.5114/wiitm.2011.24694
   Cheesborough JE, 2014, AM J SURG, V207, P504, DOI 10.1016/j.amjsurg.2013.07.040
   Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
   Erdmann D, 2001, PLAST RECONSTR SURG, V108, P2066, DOI 10.1097/00006534-200112000-00036
   Evenson AR, 2006, J GASTROINTEST SURG, V10, P455, DOI 10.1016/j.gassur.2005.08.001
   FIRME CN, 1960, SURGERY, V47, P436
   Fischer JE, 2008, AM J SURG, V196, P1, DOI 10.1016/j.amjsurg.2008.01.001
   Goverman J, 2006, J TRAUMA, V60, P428, DOI 10.1097/01.ta.0000203588.66012.c4
   Gracias VH, 2002, ARCH SURG-CHICAGO, V137, P1298, DOI 10.1001/archsurg.137.11.1298
   Medeiros AC, 2004, DIGEST SURG, V21, P401, DOI 10.1159/000082317
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   Orgill DP, 2013, INT WOUND J, V10, P15, DOI 10.1111/iwj.12170
   Pan A, 2013, INFECTION, V41, P1129, DOI 10.1007/s15010-013-0536-6
   Pfeifer J, 2011, EUR J TRAUMA EMERG S, V37, P209, DOI 10.1007/s00068-011-0104-7
   Rahbour G, 2012, ANN SURG, V256, P946, DOI 10.1097/SLA.0b013e318260aa26
   SCHECTER W., 2014, PRINCIPLES MANAGEMEN
   Turégano F, 2011, EUR J TRAUMA EMERG S, V37, P233, DOI 10.1007/s00068-011-0103-8
   Wainstein Daniel Edgardo, 2008, World J Surg, V32, P430
   Whelan C, 2005, J UROLOGY, V173, P1463, DOI 10.1097/01.ju.0000157339.05939.21
   Wong WD, 1993, INTESTINAL STOMAS, P278
NR 21
TC 20
Z9 23
U1 0
U2 2
PU VERDUCI PUBLISHER
PI ROME
PA VIA GREGORIO VII, ROME, 186-00165, ITALY
SN 1128-3602
J9 EUR REV MED PHARMACO
JI Eur. Rev. Med. Pharmacol. Sci.
PD SEP
PY 2014
VL 18
IS 17
BP 2527
EP 2532
PG 6
WC Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pharmacology & Pharmacy
GA CF0AA
UT WOS:000352203700021
PM 25268100
DA 2026-07-24
ER

PT J
AU Subramonia, S
   Pankhurst, S
   Rowlands, BJ
   Lobo, DN
AF Subramonia, Sriram
   Pankhurst, Sarah
   Rowlands, Brian J.
   Lobo, Dileep N.
TI Vacuum-Assisted Closure of Postoperative Abdominal Wounds: A Prospective
   Study
SO WORLD JOURNAL OF SURGERY
LA English
DT Article
ID PLANNED VENTRAL HERNIA; ENTEROCUTANEOUS FISTULA; FASCIAL CLOSURE;
   COMPARTMENT SYNDROME; TEMPORARY CLOSURE; WALL; MANAGEMENT; EXPERIENCE;
   TRAUMA
AB We aimed to study outcome in patients with an open abdomen in whom the abdominal vacuum-assisted closure system (V.A.C.(A (R)) Therapy((TM))) was used to provide temporary cover and achieve wound closure.
   All patients in whom V.A.C. Therapy was used to manage laparotomy wounds between February 2006 and May 2007 at a University Teaching Hospital were followed up prospectively until successful completion or stoppage of V.A.C. Therapy.
   Of the 51 consecutive patients (33 male), V.A.C. Therapy was used to manage a laparostomy in 10 patients and abdominal wound dehiscence in 41. Median (IQR) duration of V.A.C. Therapy was 17 (7-26) days. Wound healing was achieved in 31 (61%) patients, four of whom had additional surgery to assist wound closure. The rest healed by secondary intention. Treatment was withdrawn due to therapy-related complications in nine patients and due to medical or logistical reasons in seven. Four patients died while on therapy. While most V.A.C. Therapy-related problems were minor, two patients developed enteric fistulae that necessitated surgical repair. At a median (IQR) follow-up of 8 (4-13) months, 18 patients had stable cutaneous coverage with no incisional hernia, 12 developed an incisional hernia, 9 were lost to follow-up, and 12 died.
   V.A.C. Therapy is a useful adjunct in the management of the open abdomen and should be considered in the treatment of this problem. Restoration of cutaneous and fascial integrity of the abdominal wall, the risk of fistulisation, and the cost-effectiveness of this therapy require further evaluation.
C1 [Subramonia, Sriram; Rowlands, Brian J.; Lobo, Dileep N.] Univ Nottingham Hosp, Div Gastrointestinal Surg, Nottingham Digest Dis Ctr, Res Unit,Queens Med Ctr, Nottingham NG7 2UH, England.
   [Pankhurst, Sarah] Nottingham City Primary Care Trust, Sherwood Hlth Ctr, Tissue Viabil Serv, Nottingham NG5 4AD, England.
C3 University of Nottingham
RP Lobo, DN (通讯作者)，Univ Nottingham Hosp, Div Gastrointestinal Surg, Nottingham Digest Dis Ctr, Res Unit,Queens Med Ctr, Nottingham NG7 2UH, England.
EM Dileep.Lobo@nottingham.ac.uk
RI Lobo, Dileep N/AAC-6207-2020
OI Lobo, Dileep N/0000-0003-1187-5796
CR AKERS DL, 1991, J VASC SURG, V14, P48
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Banwell P E, 2003, J Wound Care, V12, P22
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Cipolla J, 2005, AM SURGEON, V71, P202
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
   Draus JM, 2006, SURGERY, V140, P570, DOI 10.1016/j.surg.2006.07.003
   Erdmann D, 2001, PLAST RECONSTR SURG, V108, P2066, DOI 10.1097/00006534-200112000-00036
   FABIAN TC, 1994, ANN SURG, V219, P643, DOI 10.1097/00000658-199406000-00007
   FANSLER RF, 1995, AM J SURG, V170, P15, DOI 10.1016/S0002-9610(99)80244-X
   Fernandez L, 1996, J TRAUMA, V40, P258, DOI 10.1097/00005373-199602000-00014
   Heller L, 2006, AM J SURG, V191, P165, DOI 10.1016/j.amjsurg.2005.09.003
   Mayberry JC, 2004, J TRAUMA, V57, P157, DOI 10.1097/01.TA.0000102411.69521.80
   Mayberry JC, 1997, ARCH SURG-CHICAGO, V132, P957
   Mendez-Eastman S, 1998, Plast Surg Nurs, V18, P27
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   MIZRAHI S, 1993, AM J SURG, V166, P62, DOI 10.1016/S0002-9610(05)80585-9
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Nagy KK, 1996, AM SURGEON, V62, P331
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   Petersson U, 2007, WORLD J SURG, V31, P2133, DOI 10.1007/s00268-007-9222-0
   Rao M, 2007, COLORECTAL DIS, V9, P266, DOI 10.1111/j.1463-1318.2006.01154.x
   SCHEIN M, 1990, ARCH SURG-CHICAGO, V125, P1516
   Stawicki S Peter, 2007, J Burns Wounds, V6, pe7
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
NR 29
TC 46
Z9 55
U1 0
U2 7
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD MAY
PY 2009
VL 33
IS 5
BP 931
EP 937
DI 10.1007/s00268-009-9947-z
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 436BH
UT WOS:000265387100006
PM 19234864
DA 2026-07-24
ER

PT J
AU Olejnik, J
   Sedlak, I
   Brychta, I
   Tibensky, I
AF Olejnik, J.
   Sedlak, I
   Brychta, I
   Tibensky, I
TI Vacuum supported laparostomy - an effective treatment of intraabdominal
   infection
SO BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
LA English
DT Article
DE vacuum supported laparostomy; vacuum assisted closure; vacuum sealing;
   staged lavage; peritonitis; severe sepsis
ID MANAGEMENT; THERAPY; CLOSURE; ABDOMEN
AB Background: Notable experience using the vacuum assisted closure for abdominal wall defects was an assumption for its intra-abdominal application in severely septic patients with intra-abdominal infection. The goal of this study was to evaluate our experience with this new therapeutic technique.
   Methods: This study is a retrospective analysis and comparison of two groups of patients with severe sepsis and proven intra-abdominal source of infection. Group A consisted of 41 patients, 31 men and 10 women with the age ranging 18-78 years old (mean 49.5), who were treated surgically between 1998 and 2002 using a combination of laparostomy, multiple irrigations and abdominal drainage. Group B consisted of 46 patients, 32 men and 14 women age 18-87 years old (mean 50.8), who were treated between 2002 and 2006 using former techniques with the addition of an intra-abdominal vacuum assisted negative pressure therapy system.
   Results: In the group A the number of re-laparotomies with debridement of the open abdominal wound in general anesthesia ranged from 5 to 18 over 10 to 35 days (mean 19.4) of hospital stay. In the group B, the number of re-laparotomies decreased to 3-9 and the hospital stay decreased to 7-29 days (mean 14.5). Fifteen patients (36.6%) in the group A died because of severe sepsis, compared to 11 patients (23.9%) in the group B.
   Conclusion: Authors confirmed a significant reduction of morbidity and mortality using the intra-abdominal vacuum assisted system in the treatment of localized intra-abdominal sepsis (Tab. 2, Ref. 18).
C1 [Olejnik, J.; Sedlak, I; Brychta, I; Tibensky, I] Sloval Med Univ, Dept Gen Surg, Derers Univ Hosp, SK-83305 Bratislava, Slovakia.
C3 Slovak Medical University Bratislava
RP Olejnik, J (通讯作者)，Sloval Med Univ, Dept Gen Surg, Derers Univ Hosp, Limbova 5, SK-83305 Bratislava, Slovakia.
EM juraj.olejnik@szu.sk
RI Brychta, Ivan/JLT-0662-2023
OI Brychta, Ivan/0009-0000-9329-093X
CR Adam U, 1997, LANGENBECKS ARCH CHI, V382, P18
   Barie P S, 2001, Curr Opin Crit Care, V7, P263, DOI 10.1097/00075198-200108000-00009
   BROCK WB, 1995, AM SURGEON, V61, P30
   Bui TD, 2006, AM J SURG, V192, P235, DOI 10.1016/j.amjsurg.2006.01.013
   Fabian TC, 2007, SURG CLIN N AM, V87, P73, DOI 10.1016/j.suc.2006.09.011
   Frankenfield DC, 1998, J AM DIET ASSOC, V98, P439, DOI 10.1016/S0002-8223(98)00100-X
   Holzheimer RG, 2001, EUR J MED RES, V6, P161
   Kirby JP, 2002, J TRAUMA, V53, P117, DOI 10.1097/00005373-200207000-00024
   Labler L, 2004, ZBL CHIR, V129, pS14, DOI 10.1055/s-2004.822668
   Olejnik J, 1999, Rozhl Chir, V78, P166
   OLEJNIK J, 2004, LEK OBZOR, V53, P261
   Rinder H.WildT, 2003, EUR SURG, V35, P41
   RUGER R, 1988, CHIRURG, V59, P598
   Schein M, 2002, LANGENBECK ARCH SURG, V387, P1, DOI 10.1007/s00423-002-0276-z
   Scott BG, 2005, SCAND J SURG, V94, P9, DOI 10.1177/145749690509400104
   Tautenhahn J, 2004, CHIRURG, V75, P492, DOI 10.1007/s00104-004-0844-6
   VOKURKA, 1995, BRATISL LEK LISTY, V96, P265
   Weidenhagen R, 2006, ZBL CHIR, V131, pS115, DOI 10.1055/s-2006-921512
NR 18
TC 19
Z9 20
U1 0
U2 2
PU COMENIUS UNIV
PI BRATISLAVA I
PA SCH MEDICINE, SPITALSKA 24, BRATISLAVA I, SK-813 72, SLOVAKIA
SN 0006-9248
J9 BRATISL MED J
JI Bratisl. Med. J.
PY 2007
VL 108
IS 7
BP 320
EP 323
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 278FJ
UT WOS:000254269700010
PM 17972552
DA 2026-07-24
ER

PT J
AU Alcala-Marquez, C
   Torrealba, R
   Mehbod, AA
   Dawson, JM
   Dressel, TD
   Transfeldt, EE
AF Alcala-Marquez, Christopher
   Torrealba, Ruben
   Mehbod, Amir A.
   Dawson, John M.
   Dressel, Thomas D.
   Transfeldt, Ensor E.
TI Recurrent Surgical Site Infections in the Spine After Treatment With the
   Vacuum-assisted Closure (VAC) System
SO CLINICAL SPINE SURGERY
LA English
DT Article
DE spine fusion; SSI; recurrent infection; VAC
ID DEEP WOUND-INFECTION; RISK-FACTORS; POSTOPERATIVE INFECTIONS; CONTINUOUS
   IRRIGATION; SURGERY; FUSION; INSTRUMENTATION; MANAGEMENT; THERAPY;
   COMPLICATIONS
AB Study Design: This study retrospectively reviewed recurrences of surgical site infections (SSI) in spinal patients treated with vacuum-assisted closure (VAC) technology.
   Objective: Identify patient and treatment factors associated with recurrence of SSI after VAC treatment.
   Summary of Background Data: Patients treated with VAC can achieve healing of deep spine wound infections; however, some patients develop a recurrent infection. Risk factors associated with a recurrence have not been identified.
   Materials and Methods: One hundred and eleven patients with SSI after spine surgery from 2002 to 2010 were studied. They had been treated with irrigation and debridement, placement of VAC, and IV antibiotics. They subsequently were taken to surgery for primary closure of their wound. Patients with SSI who healed after the initial infection treatment were compared with patients who experienced recurrence. Patient and treatment factors that were studied included smoking status, body mass index, obesity status, diagnosis of diabetes, fusion surgery, methicillin-resistant Staphylococcus aureus, or polybacteria infection, number of irrigation and debridement treatments before closure, duration of IV antibiotic treatment, and duration of treatment time with VAC. Patients with SSI who healed after the initial treatment were compared with patients who experienced recurrence.
   Results: Fourteen patients had at least one recurrence of wound infection. None of the patient or treatment factors was associated with the recurrence of a SSI.
   Conclusions: Among spine surgery patients with a SSI treated with the VAC system, those factors which predispose a patient to develop a recurrent SSI remain unknown.
C1 [Alcala-Marquez, Christopher; Torrealba, Ruben; Mehbod, Amir A.; Dawson, John M.; Dressel, Thomas D.; Transfeldt, Ensor E.] Twin Cities Spine Ctr, 913 E 26th St,Suite 600, Minneapolis, MN 55404 USA.
RP Dawson, JM (通讯作者)，Twin Cities Spine Ctr, 913 E 26th St,Suite 600, Minneapolis, MN 55404 USA.
EM jmdawson@tcspine.com
OI Dawson, John/0000-0002-9389-1580
CR Adogwa O, 2017, SPINE, V42, P520, DOI 10.1097/BRS.0000000000001779
   Akins PT, 2015, SPINE, V40, P1022, DOI 10.1097/BRS.0000000000000916
   Boody BS, 2015, J SPINAL DISORD TECH, V28, P352, DOI 10.1097/BSD.0000000000000339
   Chikawa T, 2011, BRIT J NEUROSURG, V25, P621, DOI 10.3109/02688697.2010.546902
   De la Garza-Ramos R, 2016, NEUROL RES, V38, P117, DOI 10.1080/01616412.2016.1138669
   Fang A, 2005, SPINE, V30, P1460, DOI 10.1097/01.brs.0000166532.58227.4f
   Hong HS, 2008, SPINE, V33, P2473, DOI 10.1097/BRS.0b013e3181894ff0
   Jones GA, 2007, J NEUROSURG-SPINE, V6, P407, DOI 10.3171/spi.2007.6.5.407
   Keller R B, 1972, Orthop Clin North Am, V3, P99
   Klemencsics I, 2016, SPINE J, V16, P1377, DOI 10.1016/j.spinee.2016.08.018
   Koutsoumbelis S, 2011, J BONE JOINT SURG AM, V93A, P1627, DOI 10.2106/JBJS.J.00039
   Labler L, 2006, EUR SPINE J, V15, P1388, DOI 10.1007/s00586-006-0164-2
   Lampl L, 2009, ANASTH INTENSIV NOTF, V44, P652, DOI 10.1055/s-0029-1242433
   Levi ADO, 1997, J NEUROSURG, V86, P975, DOI 10.3171/jns.1997.86.6.0975
   Lian XF, 2014, J SPINAL DISORD TECH, V27, pE315, DOI 10.1097/BSD.0000000000000122
   Lim S, 2018, SPINE, V43, P215, DOI 10.1097/BRS.0000000000000608
   LONSTEIN J, 1973, CLIN ORTHOP RELAT R, P222
   Mangram AJ, 1999, PEARSON ML GUIDELINE
   Mehbod AA, 2005, J SPINAL DISORD TECH, V18, P14, DOI 10.1097/01.bsd.0000133493.32503.d3
   Molinari Robert W, 2012, Eur Spine J, V21 Suppl 4, pS476, DOI 10.1007/s00586-011-2104-z
   Pahys JM, 2013, J BONE JOINT SURG AM, V95A, P549, DOI 10.2106/JBJS.K.00756
   Pereira BJA, 2016, CLIN NEUROL NEUROSUR, V140, P1, DOI 10.1016/j.clineuro.2015.11.004
   Picada R, 2000, J SPINAL DISORD, V13, P42, DOI 10.1097/00002517-200002000-00009
   Ploumis A, 2008, J SPINAL DISORD TECH, V21, P320, DOI 10.1097/BSD.0b013e318141f99d
   Rao SB, 2011, CLIN INFECT DIS, V53, P686, DOI 10.1093/cid/cir506
   Schimmel JJP, 2010, EUR SPINE J, V19, P1711, DOI 10.1007/s00586-010-1421-y
   Schoenfeld AJ, 2013, SPINE J, V13, P1171, DOI 10.1016/j.spinee.2013.02.071
   Sielatycki JA, 2015, SPINE, V40, P1934, DOI 10.1097/BRS.0000000000001101
   Smith JS, 2010, SPINE, V35, P2140, DOI 10.1097/BRS.0b013e3181cbc8e7
   Tan KJ, 2010, J BONE JOINT SURG BR, V92B, P401, DOI 10.1302/0301-620X.92B3.22115
   ter Gunne AFP, 2010, SPINE J, V10, P129, DOI 10.1016/j.spinee.2009.10.002
   Transfeldt E., 1985, ORTHOPEDIC T, V9, P128
   Wimmer C, 1998, J SPINAL DISORD, V11, P124
   Wimmer C, 1996, J SPINAL DISORD, V9, P505
   Yuan-Innes M J, 2001, Spine (Phila Pa 1976), V26, pE30
NR 35
TC 9
Z9 12
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 2380-0186
J9 CLIN SPINE SURG
JI Clin. Spine Surg.
PD OCT
PY 2018
VL 31
IS 8
BP 351
EP 355
DI 10.1097/BSD.0000000000000668
PG 5
WC Clinical Neurology; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Orthopedics
GA GW0BE
UT WOS:000446526000007
PM 29889107
DA 2026-07-24
ER

PT J
AU Benech, A
   Arcuri, F
   Poglio, G
   Brucoli, M
   Guglielmetti, R
   Crespi, MC
   Pia, F
AF Benech, A.
   Arcuri, F.
   Poglio, G.
   Brucoli, M.
   Guglielmetti, R.
   Crespi, M. C.
   Pia, F.
TI Vacuum-assisted closure therapy in reconstructive surgery
SO ACTA OTORHINOLARYNGOLOGICA ITALICA
LA English
DT Article
DE Fibular free flap; Subatmospheric pressure; Maxillofacial wound; VAC
   therapy
ID PRESSURE WOUND THERAPY; PROLIFERATION; FOUNDATION; MANAGEMENT; FRACTURES
AB In 1997, supported by experimental work, Argenta published a clinical report describing a variety of complicated wounds whose treatment responded successfully to negative pressure dressings using a vacuum-assisted closure system (VAC) (Kinetic Concepts Inc., San Antonio, TX). This system has been successfully used in the fields of orthopaedics and traumatology, general surgery, plastic and reconstructive surgery and gynaecology/obstetrics for a large variety of complicated wounds located in several regions, particularly in the torso and extremities. To the best of our knowledge, the use of the VAC therapy in treating free flaps surgical wounds has not been discussed in the literature. Since 2009 at the Novara Major Hospital, we have been using the VAC therapy in selected cases for difficult and complicated wounds of the maxillofacial region. The purpose of this study is to describe and discuss three cases undergoing VAC therapy followed by loco-regional flaps in the management of exposed bone after fibular free flap. The advantages and disadvantages of VAC therapy in treating complicated wounds have been reported by several studies; compared with conventional wet-to-dry dressings, this system eliminates interstitial oedema, exudates and debrides while increasing blood perfusion leading to a more rapid promotion of wound healing with less bacterial loading. Although surgical debridement, wet-to-dry dressing changes and antibiotic treatment are the mainstay in managing maxillofacial wounds, VAC therapy can be used to obtain primary closure or to prepare the wound bed until definitive reconstruction is carried out. In our opinion, the VAC technique is an innovative therapy, and at our institution represents the standard of care for the majority of complicated wounds.
C1 [Benech, A.; Arcuri, F.; Poglio, G.; Brucoli, M.] Piemonte Orientale Univ, Maxillofacial Unit, Novara, Italy.
   [Guglielmetti, R.; Crespi, M. C.; Pia, F.] Piemonte Orientale Univ, Otorhinolaryngol Clin, Novara, Italy.
C3 University of Eastern Piedmont Amedeo Avogadro; University of Eastern
   Piedmont Amedeo Avogadro
RP Arcuri, F (通讯作者)，Osped Maggiore La Carita, SCDU Chirurg Maxillofacciale, Corso Mazzini 18, I-28100 Novara, Italy.
EM fraarcuri@libero.it
OI Poglio, Giuseppe/0000-0001-6867-048X; BRUCOLI,
   Matteo/0000-0002-2867-1936; BENECH, Arnaldo/0000-0003-1905-1089
CR Andrews BT, 2006, HEAD NECK-J SCI SPEC, V28, P974, DOI 10.1002/hed.20496
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Byrnside V, 2010, J ORAL MAXIL SURG, V68, P935, DOI 10.1016/j.joms.2009.09.113
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Dhir K, 2009, LARYNGOSCOPE, V119, P54, DOI 10.1002/lary.20000
   Fabian TS, 2000, AM SURGEON, V66, P1136
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Greer S E, 1999, J Wound Ostomy Continence Nurs, V26, P250
   Hopf H W, 2001, Foot Ankle Clin, V6, P661, DOI 10.1016/S1083-7515(02)00008-6
   Loree S, 2004, J Wound Care, V13, P249
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   Miller Quintessa, 2004, Curr Surg, V61, P205, DOI 10.1016/j.cursur.2003.07.015
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Parrett BM, 2006, PLAST RECONSTR SURG, V117, P1315, DOI 10.1097/01.prs.0000204959.18136.36
   Philbeck T E Jr, 1999, Ostomy Wound Manage, V45, P41
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Schuster R, 2006, AM SURGEON, V72, P129
   Ubbink DT, 2011, TOPICAL NEGATIVE PRE
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
NR 21
TC 20
Z9 23
U1 0
U2 2
PU PACINI EDITORE
PI PISA
PA VIA DELLA GHERARDESCA-ZONA INDUSTRIALE OSPEDALETTO, 56121 PISA, ITALY
SN 0392-100X
EI 1827-675X
J9 ACTA OTORHINOLARYNGO
JI Acta Otorhinolaryngol. Ital.
PD JUN
PY 2012
VL 32
IS 3
BP 192
EP 197
PG 6
WC Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology
GA 967BQ
UT WOS:000305881500009
PM 22767986
DA 2026-07-24
ER

PT J
AU Murray, W
   Davey, MG
   Robb, W
   Donlon, NE
AF Murray, William
   Davey, Mathew G.
   Robb, William
   Donlon, Noel E.
TI Management of esophageal anastomotic leaks, a systematic review and
   network meta-analysis
SO DISEASES OF THE ESOPHAGUS
LA English
DT Review
DE Esophagus; SEMS; EVAC; anastomotic leak
ID VACUUM-ASSISTED CLOSURE; THERAPY; STENT; COMPLICATIONS; PERFORATIONS;
   EFFICACY
AB There is currently no consensus as to how to manage esophageal anastomotic leaks. Intervention with endoscopic vacuum-assisted closure (EVAC), stenting, reoperation, and conservative management have all been mooted as potential options. To conduct a systematic review and network meta-analysis (NMA) to evaluate the optimal management strategy for esophageal anastomotic leaks. A systematic review was performed as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines with extension for NMA. NMA was performed using R packages and Shiny. In total, 12 retrospective studies were included, which included 511 patients. Of the 449 patients for whom data regarding sex was available, 371 (82.6%) were male, 78 (17.4%) were female. The average age of patients was 62.6 years (standard deviation 10.2). The stenting cohort included 245 (47.9%) patients. The EVAC cohort included 123 (24.1%) patients. The conservative cohort included 87 (17.0%) patients. The reoperation cohort included 56 (10.9%) patients. EVAC had a significantly decreased complication rate compared to stenting (odds ratio 0.23 95%, confidence interval [CI] 0.09;0.58). EVAC had a significantly lower mortality rate than stenting (odds ratio 0.43, 95% CI 0.21; 0.87). Reoperation was used in significantly larger leaks than stenting (mean difference 14.66, 95% CI 4.61;24.70). The growing use of EVAC as a first-line intervention in esophageal anastomotic leaks should continue given its proven effectiveness and significant reduction in both complication and mortality rates. Surgical management is often necessary for significantly larger leaks and will likely remain an effective option in uncontained leaks with systemic features.
C1 [Murray, William; Davey, Mathew G.; Robb, William; Donlon, Noel E.] Beaumont Hosp, Dept Upper Gastrointestinal Surg, Dublin, Ireland.
   [Murray, William] Monaire Lower Shelbourne Rd, Limerick V94A6NT, Ireland.
C3 Beaumont Hospital Dublin
RP Murray, W (通讯作者)，Monaire Lower Shelbourne Rd, Limerick V94A6NT, Ireland.
EM 10murrayw@gmail.com; mattgdavey1@gmail.com; robb.will@gmail.com;
   donlonn@tcd.ie
OI Donlon, Noel/0000-0002-4073-3896; Murray, William/0000-0001-5726-710X
CR Al-Issa MA, 2014, SAUDI J GASTROENTERO, V20, P39, DOI 10.4103/1319-3767.126315
   Alanezi Khaled, 2004, Ann Thorac Cardiovasc Surg, V10, P71
   [Anonymous], About us
   Aziz M, 2021, ENDOSC INT OPEN, V09, pE1371, DOI 10.1055/a-1508-5947
   Bachmann J, 2022, WORLD J SURG ONCOL, V20, DOI 10.1186/s12957-022-02551-z
   Balduzzi S, 2023, J STAT SOFTW, V106, P1, DOI 10.18637/jss.v106.i02
   Berlth F, 2019, J GASTROINTEST SURG, V23, P67, DOI 10.1007/s11605-018-4000-x
   Bi YH, 2019, RADIOL MED, V124, P1253, DOI 10.1007/s11547-019-01074-0
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Cameron C, 2015, SYST REV, V4, DOI 10.1186/s13643-015-0133-0
   Chandan S, 2020, GASTROINTEST ENDOSC, V91, pAB393, DOI 10.1016/j.gie.2020.03.2436
   Choi SI, 2020, GUT LIVER, V14, P746
   Crestanello JA, 2005, J THORAC CARDIOV SUR, V129, P254, DOI 10.1016/j.jtcvs.2004.10.024
   Dai YY, 2011, J THORAC CARDIOV SUR, V141, P1213, DOI 10.1016/j.jtcvs.2010.07.096
   El-Sourani N, 2022, CLIN ENDOSC, V55, P58, DOI 10.5946/ce.2021.099
   Fabbi M, 2021, DIS ESOPHAGUS, V34, DOI 10.1093/dote/doaa039
   Famiglietti A, 2020, J THORAC DIS, V12, P1022, DOI 10.21037/jtd.2020.01.15
   Gockel Ines, 2005, World J Surg Oncol, V3, P37, DOI 10.1186/1477-7819-3-37
   Griffin SM, 2002, J AM COLL SURGEONS, V194, P285, DOI 10.1016/S1072-7515(01)01177-2
   Guo JT, 2014, WORLD J SURG ONCOL, V12, DOI 10.1186/1477-7819-12-402
   Hozo S., 2005, BMC MED RES METHODOL, V5, P13, DOI DOI 10.1186/1471-2288-5-13
   Hua F, 2023, THORAC CANCER, V14, P339, DOI 10.1111/1759-7714.14734
   Hünerbein M, 2004, ANN SURG, V240, P801, DOI 10.1097/01.sla.0000143122.76666.ae
   Hwang JJ, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000003416
   Jansen JP, 2013, BMC MED, V11, DOI 10.1186/1741-7015-11-159
   Kaczmarek DJ, 2022, BMC GASTROENTEROL, V22, DOI 10.1186/s12876-022-02346-2
   Kujawski Krzysztof, 2012, Med Sci Monit, V18, pCR323
   Langer FB, 2005, ANN THORAC SURG, V79, P398, DOI 10.1016/j.athoracsur.2004.07.006
   Lee DH, 2013, DIS ESOPHAGUS, V26, P609, DOI 10.1111/dote.12011
   Licht E, 2016, ANN THORAC SURG, V101, P301, DOI 10.1016/j.athoracsur.2015.06.072
   Livingstone I, 2021, CLIN ENDOSC, V54, P787
   Low DE, 2019, ANN SURG, V269, P291, DOI 10.1097/SLA.0000000000002611
   Manghelli JL, 2019, J THORAC DIS, V11, P131, DOI 10.21037/jtd.2018.12.13
   Mennigen R, 2015, J GASTROINTEST SURG, V19, P1229, DOI 10.1007/s11605-015-2847-7
   Min YW, 2019, BMC SURG, V19, DOI 10.1186/s12893-019-0497-5
   Nguyen NT, 2011, J GASTROINTEST SURG, V15, P1952, DOI 10.1007/s11605-011-1658-8
   Noh SM, 2018, GASTROENT RES PRACT, V2018, DOI 10.1155/2018/1697968
   Persson S, 2017, DIS ESOPHAGUS, V30, DOI 10.1093/dote/dox108
   Qin JJ, 2010, J THORAC ONCOL, V5, P251, DOI 10.1097/JTO.0b013e3181c6e5f9
   RIBET M, 1992, J THORAC CARDIOV SUR, V103, P784
   Schaheen L, 2014, AM J SURG, V208, P536, DOI 10.1016/j.amjsurg.2014.05.011
   Schniewind B, 2013, SURG ENDOSC, V27, P3883, DOI 10.1007/s00464-013-2998-0
   Schubert D, 2005, GASTROINTEST ENDOSC, V61, P891, DOI 10.1016/S0016-5107(05)00325-1
   Scognamiglio P, 2022, BMC SURG, V22, DOI 10.1186/s12893-022-01764-z
   Tachezy M, 2021, TRIALS, V22, DOI 10.1186/s13063-021-05315-4
   Tuebergen D, 2008, J GASTROINTEST SURG, V12, P1168, DOI 10.1007/s11605-008-0500-4
   Ubels S., 2022, DIS ESOPHAGUS, V36
   URSCHEL JD, 1995, AM J SURG, V169, P634, DOI 10.1016/S0002-9610(99)80238-4
   van Boeckel PGA, 2012, BMC GASTROENTEROL, V12, DOI 10.1186/1471-230X-12-19
   van der Schaaf M, 2014, BMJ OPEN, V4, DOI 10.1136/bmjopen-2013-004648
   van der Werf LR, 2020, ANN SURG, V271, P1095, DOI 10.1097/SLA.0000000000003210
   Verstegen MHP, 2021, WORLD J SURG, V45, P3341, DOI 10.1007/s00268-021-06250-w
   Wan X, 2014, BMC MED RES METHODOL, V14, DOI 10.1186/1471-2288-14-135
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Whooley BP, 2001, ANN SURG, V233, P338, DOI 10.1097/00000658-200103000-00006
NR 55
TC 9
Z9 9
U1 0
U2 0
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1120-8694
EI 1442-2050
J9 DIS ESOPHAGUS
JI Dis. Esophagus
PD MAR 24
PY 2024
VL 37
IS 7
DI 10.1093/dote/doae019
EA MAR 2024
PG 7
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA XK2C2
UT WOS:001190013400001
PM 38525940
DA 2026-07-24
ER

PT J
AU Pines, G
   Bar, I
   Elami, A
   Sapojnikov, S
   Hikri, O
   Ton, D
   Mosenkis, B
   Melzer, E
AF Pines, Guy
   Bar, Ilan
   Elami, Amir
   Sapojnikov, Shimon
   Hikri, Ofir
   Ton, Dennis
   Mosenkis, Bruce
   Melzer, Ehud
TI Modified Endoscopic Vacuum Therapy for Nonhealing Esophageal Anastomotic
   Leak: Technique Description and Review of Literature
SO JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
LA English
DT Article
DE endoscopic treatment; esophageal fistula; anastomotic leakage;
   esophagectomy
ID THE-SCOPE-CLIP; UPPER GASTROINTESTINAL-TRACT; RECURRENT
   TRACHEOESOPHAGEAL FISTULA; FIBRIN GLUE INJECTION; ASSISTED CLOSURE;
   MULTICENTER EXPERIENCE; CLINICAL-OUTCOMES; TREATMENT OPTIONS; BEAR CLAW;
   MANAGEMENT
AB Background: Endoscopic vacuum-assisted closure (EVAC) therapy is increasingly being used as a new promising method for repairing upper gastrointestinal defects of different etiologies with high success rates. EVAC therapy consists of placing a sponge either within the lumen or within an abscess cavity connected with a nasogastric (NG) tube to a negative pressure system, thus decreasing bacterial contamination and edema and promoting granulation tissue proliferation, thereby gradually decreasing the cavity size until complete closure. Herein, we describe a modified technique for EVAC therapy in which the NG tube is passed into the esophagus through an existing intrapleural drain tract using a rendezvous technique. The small residual fistula was amendable to fibrin glue embolization. This allows easier sponge placement and exchange compared to traditional EVAC technique, and allows oral intake during treatment. We also review the literature regarding other endoscopic treatment options for esophageal anastomotic leaks and perforations.
   Methods: The PubMed database was searched using the terms "esophagus," "esophageal," "leak," "fistula," "endoluminal vacuum-assisted closure (VAC)," "endoscopic VAC," "stent," "sealant," "glue," and "over-the-scope clip (OTSC)" Reference lists of identified articles were searched for further articles, and the "similar articles" function was used on all included articles.
   Results: Complete closure of the nonhealing fistula was achieved after 8 days of EVAC treatment and fibrin glue embolization.
   Conclusions: Modified EVAC technique as described is feasible and safe. To the best of our knowledge, this is the first description of this technique. The technique allows easier sponge placement and exchange compared to traditional EVAC technique, and allows oral intake during treatment.
C1 [Pines, Guy; Bar, Ilan; Elami, Amir; Hikri, Ofir] Kaplan Med Ctr, Dept Thorac Surg, POB 1, IL-76100 Rehovot, Israel.
   [Sapojnikov, Shimon] Kaplan Med Ctr, Dept Surg, Rehovot, Israel.
   [Ton, Dennis] Kaplan Med Ctr, Dept Invas Radiol, Rehovot, Israel.
   [Mosenkis, Bruce; Melzer, Ehud] Kaplan Med Ctr, Dept Gastroenterol & Liver Dis, Rehovot, Israel.
   [Mosenkis, Bruce; Melzer, Ehud] Hebrew Univ Jerusalem, Sch Med, POB 1, IL-76100 Rehovot, Israel.
C3 Hebrew University of Jerusalem; Kaplan Medical Center; Hebrew University
   of Jerusalem; Kaplan Medical Center; Hebrew University of Jerusalem;
   Kaplan Medical Center; Hebrew University of Jerusalem; Kaplan Medical
   Center; Hebrew University of Jerusalem
RP Pines, G (通讯作者)，Kaplan Med Ctr, Dept Thorac Surg, POB 1, IL-76100 Rehovot, Israel.; Pines, G (通讯作者)，Hebrew Univ Jerusalem, Sch Med, POB 1, IL-76100 Rehovot, Israel.
EM guypi@clalit.org.il
RI Pines, Guy/A-4251-2017
OI Pines, Guy/0000-0003-2923-660X
CR Ahn JY, 2010, GUT LIVER, V4, P508, DOI 10.5009/gnl.2010.4.4.508
   Ahrens M, 2010, ENDOSCOPY, V42, P693, DOI 10.1055/s-0030-1255688
   Alanezi Khaled, 2004, Ann Thorac Cardiovasc Surg, V10, P71
   [Anonymous], 2013, Gastrointest Endosc
   Bludau M, 2014, SURG ENDOSC, V28, P896, DOI 10.1007/s00464-013-3244-5
   Böhm G, 2010, ENDOSCOPY, V42, P599, DOI 10.1055/s-0029-1244165
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Cardona AB, 2005, EJSO-EUR J SURG ONC, V31, P1222, DOI 10.1016/j.ejso.2005.08.001
   Crestanello JA, 2005, J THORAC CARDIOV SUR, V129, P254, DOI 10.1016/j.jtcvs.2004.10.024
   Dasari BVM, 2014, ANN SURG, V259, P852, DOI 10.1097/SLA.0000000000000564
   Farra J, 2010, PEDIATR SURG INT, V26, P237, DOI 10.1007/s00383-009-2524-6
   Freeman RK, 2012, ANN THORAC SURG, V94, P959, DOI 10.1016/j.athoracsur.2012.05.047
   Haito-Chavez Y, 2014, GASTROINTEST ENDOSC, V80, P610, DOI 10.1016/j.gie.2014.03.049
   Heits N, 2014, ANN THORAC SURG, V97, P1029, DOI 10.1016/j.athoracsur.2013.11.014
   Hoeppner J, 2014, SURG ENDOSC, V28, P1703, DOI 10.1007/s00464-013-3379-4
   Irani S, 2014, GASTROINTEST ENDOSC, V79, P844, DOI 10.1016/j.gie.2013.12.012
   Iwata T, 2012, ENDOSCOPY, V44, pE317, DOI 10.1055/s-0032-1309849
   Kimura T, 2013, ANN THORAC CARDIOVAS, V19, P289, DOI 10.5761/atcs.cr.12.01906
   Krishna SG, 2016, GASTROINTEST ENDOSC, V84, P850, DOI 10.1016/j.gie.2016.05.018
   Kuehn F, 2016, J GASTROINTEST SURG, V20, P237, DOI 10.1007/s11605-015-3044-4
   Labori KJ, 2009, SCAND J GASTROENTERO, V44, P1491, DOI 10.3109/00365520903362610
   Laukoetter MG, 2017, SURG ENDOSC, V31, P2687, DOI 10.1007/s00464-016-5265-3
   Lee DH, 2013, DIS ESOPHAGUS, V26, P609, DOI 10.1111/dote.12011
   López J, 2015, SURG INNOV, V22, P88, DOI 10.1177/1553350614535860
   Mennigen R, 2014, WORLD J GASTROENTERO, V20, P7767, DOI 10.3748/wjg.v20.i24.7767
   Mönkemüller K, 2012, GASTROINTEST ENDOSC, V76, P1077, DOI 10.1016/j.gie.2012.06.009
   Möschler O, 2014, Z GASTROENTEROL, V52, P281, DOI 10.1055/s-0033-1356441
   Möschler O, 2015, ENDOSC INT OPEN, V3, pE554, DOI 10.1055/s-0034-1392568
   Mudumbi S, 2014, ENDOSCOPY, V46, P1106, DOI 10.1055/s-0034-1377916
   Neumann H, 2012, GASTROINTEST ENDOSC, V76, P1009, DOI 10.1016/j.gie.2012.07.036
   Ojima T, 2014, ENDOSCOPY, V46, pE62, DOI 10.1055/s-0033-1359159
   Ono H, 2015, ESOPHAGUS-TOKYO, V12, P336, DOI 10.1007/s10388-014-0462-4
   Papavramidis ST, 2004, GASTROINTEST ENDOSC, V59, P296, DOI 10.1016/S0016-5107(03)02545-8
   Papavramidis TS, 2008, J GASTROEN HEPATOL, V23, P1802, DOI 10.1111/j.1440-1746.2008.05545.x
   Pramateftakis Manousos-Georgios, 2011, J Med Case Rep, V5, P96, DOI 10.1186/1752-1947-5-96
   Rabago L R, 2000, Gastroenterol Hepatol, V23, P82
   Richter GT, 2008, J PEDIATR SURG, V43, P238, DOI 10.1016/j.jpedsurg.2007.08.062
   Rodella L, 1998, ENDOSCOPY, V30, P453, DOI 10.1055/s-2007-1001307
   Rutegård M, 2012, ANN SURG ONCOL, V19, P99, DOI 10.1245/s10434-011-1926-6
   Schniewind B, 2013, SURG ENDOSC, V27, P3883, DOI 10.1007/s00464-013-2998-0
   Schorsch T, 2014, CHIRURG, V85, P1081, DOI 10.1007/s00104-014-2764-4
   Seewald S, 2002, GASTROINTEST ENDOSC, V56, P916, DOI 10.1067/mge.2002.129873
   Smallwood NR, 2016, SURG ENDOSC, V30, P2473, DOI 10.1007/s00464-015-4501-6
   Sulz MC, 2014, WORLD J GASTROENTERO, V20, P16287, DOI 10.3748/wjg.v20.i43.16287
   Vanbiervliet G, 2012, SURG ENDOSC, V26, P53, DOI 10.1007/s00464-011-1827-6
   Vinnamala S, 2014, ENDOSCOPY, V46, pE481, DOI 10.1055/s-0034-1377535
   Wang CX, 2015, CAN J SURG, V58, P378, DOI 10.1503/cjs.002615
   Wedemeyer J, 2010, GASTROINTEST ENDOSC, V71, P382, DOI 10.1016/j.gie.2009.07.011
   Weidenhagen R, 2008, Rozhl Chir, V87, P397
   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
   Weidenhagen R, 2010, ANN THORAC SURG, V90, P1674, DOI 10.1016/j.athoracsur.2010.07.007
   Wilcox VT, 2015, SURG ENDOSC, V29, P24, DOI 10.1007/s00464-014-3640-5
   Yang J, 2017, SURG ENDOSC, V31, P1414, DOI 10.1007/s00464-016-5131-3
   Yoshikane H, 1997, GASTROINTEST ENDOSC, V46, P464, DOI 10.1016/S0016-5107(97)70045-2
   Youn HC, 2016, ANN THORAC CARDIOVAS, V22, P363, DOI 10.5761/atcs.cr.15-00305
NR 55
TC 31
Z9 40
U1 0
U2 6
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1092-6429
EI 1557-9034
J9 J LAPAROENDOSC ADV S
JI J. Laparoendosc. Adv. Surg. Tech.
PD JAN
PY 2018
VL 28
IS 1
BP 33
EP 40
DI 10.1089/lap.2017.0318
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FS5EY
UT WOS:000419818100006
PM 29019713
DA 2026-07-24
ER

PT J
AU Egin, S
AF Egin, Seracettin
TI A new scoring system for the prediction of mortality in Fournier's
   gangrene: The Egin score
SO ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA &
   EMERGENCY SURGERY
LA English
DT Article
DE Fournier's gangrene; Fournier's Gangrene Severity Index; Uludag
   Fournier's Gangrene Severity Index; mortality; vacuum-assisted closure
ID OUTCOME PREDICTION; THERAPY
AB BACKGROUND: This study aimed to investigate the factors affecting mortality in Fournier's gangrene (FG) and to establish a simplified scoring system that enables practical bedside assessment for clinicians. METHODS: The medical records of 130 patients treated for FG between February 2012 and January 2025 were retrospectively reviewed. Survivors (Group 1, n=101) were analyzed separately from non-survivors (Group 2, n=29). The collected data included sex, source of infection, presence of diabetes mellitus (DM), obesity, and other comorbidities. Additional variables included the presence of a diverting stoma, duration of vacuum-assisted closure (VAC) therapy, length of hospital stay, intensive care period (ICP), and isolated bacterial species. Associations between mortality and factors such as age, infection spread score, comorbidities other than DM and obesity (CADO), and ICP were examined. RESULTS: A significant difference was observed between the groups in terms of age and age score. The infection spread score was significantly higher in Group 2. While 60 patients in Group 1 had CADO, all patients in Group 2 had CADO, demonstrating a statistically significant difference. ICP was also significantly longer among non-survivors. Receiver operating characteristic (ROC) analysis demonstrated that the Egin score had a sensitivity of 96.6% and a specificity of 63.4% at a threshold value of >3. CONCLUSION: Age, infection spread score, CADO, and ICP, which constitute the Egin score, demonstrated significant differences between survivors and non-survivors. These parameters are crucial for predicting mortality in patients with FG.
C1 [Egin, Seracettin] Univ Hlth Sci, Istanbul Prof Dr Cemil Tascioglu City Hosp, Dept Gen Surg, Istanbul, Turkiye.
C3 University of Health Sciences Turkey
RP Egin, S (通讯作者)，Univ Hlth Sci, Istanbul Prof Dr Cemil Tascioglu City Hosp, Dept Gen Surg, Istanbul, Turkiye.
EM seracettin_egin@hotmail.com
RI Eğin, Seracettin/GQZ-0908-2022
OI Eğin, Seracettin/0000-0002-4090-5205
CR Çomçali B, 2022, ULUS TRAVMA ACIL CER, V28, P490, DOI 10.14744/tjtes.2020.68137
   Marín AG, 2015, CIR ESPAN, V93, P12, DOI 10.1016/j.ciresp.2014.03.017
   Kuchinka Jakub, 2019, Pol Przegl Chir, V92, P1, DOI 10.5604/01.3001.0013.5894
   Kuzaka B, 2018, MED SCI MONITOR, V24, DOI 10.12659/MSM.905836
   LAOR E, 1995, J UROLOGY, V154, P89, DOI 10.1016/S0022-5347(01)67236-7
   Lewis GD, 2021, CUREUS J MED SCIENCE, V13, DOI 10.7759/cureus.18948
   Lin TY, 2014, INT J UROL, V21, P696, DOI 10.1111/iju.12426
   Morpurgo E, 2002, SURG CLIN N AM, V82, P1213, DOI 10.1016/S0039-6109(02)00058-0
   Ozturk E, 2011, COLORECTAL DIS, V13, P1044, DOI 10.1111/j.1463-1318.2010.02353.x
   Ozturk E, 2009, AM J SURG, V197, P660, DOI 10.1016/j.amjsurg.2008.04.018
   Raizandha MA, 2022, INT BRAZ J UROL, V48, P771, DOI 10.1590/S1677-5538.IBJU.2022.0119
   Roghmann F, 2012, BJU INT, V110, P1359, DOI 10.1111/j.1464-410X.2012.11082.x
   Singh A, 2016, ARCH ITAL UROL ANDRO, V88, P157, DOI 10.4081/aiua.2016.3.157
   Thayer J, 2020, PRS-GLOB OPEN, V8, DOI 10.1097/GOX.0000000000003034
   Tufano A, 2023, J PERS MED, V13, DOI 10.3390/jpm13091283
   Yilmazlar T, 2010, TECH COLOPROCTOL, V14, P217, DOI 10.1007/s10151-010-0592-1
   Yilmazlar T, 2014, ULUS TRAVMA ACIL CER, V20, P333, DOI 10.5505/tjtes.2014.06870
NR 17
TC 0
Z9 0
U1 0
U2 0
PU TURKISH ASSOC TRAUMA EMERGENCY SURGERY
PI ISTANBUL
PA KOPRULU MEHMET PASA SOC, DENIZ ABDAL MAH, DADASOGLU AP, 25-1 SEHREMINI,
   ISTANBUL, 00000, Turkiye
SN 1306-696X
EI 1307-7945
J9 ULUS TRAVMA ACIL CER
JI Ulus. Travma Acil Cerrahi Derg.
PD MAR
PY 2026
VL 32
IS 3
BP 270
EP 278
DI 10.14744/tjtes.2025.55901
PG 9
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA FA3PG
UT WOS:001714019100006
PM 41992996
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Rajabaleyan, P
   Vang, A
   Möller, S
   Khalaf, S
   Ladegaard, AG
   Qvist, N
   Ellebaek, MB
AF Rajabaleyan, Pooya
   Vang, Ask
   Moller, Soren
   Khalaf, Sardar
   Ladegaard, Anna Gosvig
   Qvist, Niels
   Ellebaek, Mark Bremholm
TI Vacuum-Assisted Closure Significantly Reduces Surgical Postoperative
   Complications Compared With Primary Abdominal Closure in Patients With
   Secondary Peritonitis: A Comparative Retrospective Study
SO WORLD JOURNAL OF SURGERY
LA English
DT Article
DE open abdomen; secondary peritonitis; vacuum-assisted closure
ID PRESSURE WOUND THERAPY; OPEN ABDOMEN; NEGATIVE-PRESSURE; DAMAGE CONTROL;
   PLANNED RELAPAROTOMY; SEPSIS; MANAGEMENT; TRAUMA; SURGERY; LAPAROSTOMY
AB Background: Vacuum-assisted abdominal closure (VAC) is being increasingly used as an adjunctive procedure in the surgical treatment of secondary peritonitis. This study compared postoperative mortality and complication rates between VAC and primary abdominal closure (PAC). Method: This retrospective chart review included all patients diagnosed with secondary peritonitis who underwent laparotomy between 2010 and 2019. Data were collected from six hospitals within Southern Denmark, covering a population of approximately 1,225,000 inhabitants. Results: The study involved 315 patients (139 in the PAC and 176 in the VAC groups). In the VAC group, BMI, ASA, SOFA, MPI, and four quadrant contamination was significantly higher at the index operation. There were no significant differences in nonadjusted and adjusted postoperative mortality at 30 days, 90 days, and 1 year, with cumulative values of 13%, 16%, and 21%, respectively, compared with 16%, 21%, and 31%, in the PAC group (p = 0.519, p = 0.380, and p = 0.051, respectively). Cumulative adjusted surgical postoperative complications at 30 days, 90 days, and 1 year, as assessed by the comprehensive complication index, was significantly higher in the PAC group. Reoperations were significantly more common in the PAC group. The total length of the intensive care unit admission was significantly longer in the VAC group, with a mean of 9.0 +/- 12.1 versus 6.7 +/- 12.1 days (p < 0.001). Conclusion: VAC after laparotomy for secondary peritonitis did not significantly reduce mortality but increased ICU stay, whereas primary closure led to higher surgical complication rates and reoperations.
C1 [Rajabaleyan, Pooya; Vang, Ask; Khalaf, Sardar; Ladegaard, Anna Gosvig; Qvist, Niels; Ellebaek, Mark Bremholm] Odense Univ Hosp, Res Unit Surg, Odense, Denmark.
   [Rajabaleyan, Pooya; Moller, Soren; Qvist, Niels; Ellebaek, Mark Bremholm] Odense Univ Hosp, Open Patient Data Explorat Network OPEN, Odense, Denmark.
   [Rajabaleyan, Pooya; Moller, Soren; Qvist, Niels; Ellebaek, Mark Bremholm] Univ Southern Denmark, Dept Clin Res, Odense, Denmark.
C3 University of Southern Denmark; Odense University Hospital; University
   of Southern Denmark; Odense University Hospital; University of Southern
   Denmark
RP Rajabaleyan, P (通讯作者)，Odense Univ Hosp, Res Unit Surg, Odense, Denmark.; Rajabaleyan, P (通讯作者)，Odense Univ Hosp, Open Patient Data Explorat Network OPEN, Odense, Denmark.
EM Pooya.rajabaleyan@skane.se
RI ; Möller, Sören/X-8738-2019
OI Rajabaleyan, Pooya/0000-0002-6882-9427; Ellebaek, Mark
   Bremholm/0000-0001-6550-7505; Möller, Sören/0000-0003-0858-4269; ,
   Sardar Khalaf/0009-0008-4358-4663
FU Region Syddanmark
FX The authors have nothing to report.
CR Adkins AL, 2004, AM SURGEON, V70, P137
   Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
   Anaya Daniel A, 2003, Surg Infect (Larchmt), V4, P355, DOI 10.1089/109629603322761418
   Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
   Bensignor T, 2018, WORLD J SURG, V42, P3589, DOI 10.1007/s00268-018-4687-6
   Berg A, 2022, LANGENBECK ARCH SURG, V407, P259, DOI 10.1007/s00423-021-02304-8
   Bertelsen CA, 2014, WORLD J SURG, V38, P774, DOI 10.1007/s00268-013-2360-7
   Bleszynski MS, 2016, AM J SURG, V211, P926, DOI 10.1016/j.amjsurg.2016.01.012
   BOHNEN JMA, 1988, ARCH SURG-CHICAGO, V123, P225
   Chiara O, 2016, J TRAUMA ACUTE CARE, V80, P173, DOI 10.1097/TA.0000000000000882
   Coccolini F, 2023, WORLD J EMERG SURG, V18, DOI 10.1186/s13017-023-00509-4
   Coccolini F, 2019, INJURY, V50, P160, DOI 10.1016/j.injury.2018.09.040
   Coccolini F, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0167-4
   Cotton BA, 2011, ANN SURG, V254, P598, DOI 10.1097/SLA.0b013e318230089e
   Diaz JJ, 2010, J TRAUMA, V68, P1425, DOI 10.1097/TA.0b013e3181da0da5
   Emr B, 2014, SHOCK, V41, P317, DOI 10.1097/SHK.0000000000000121
   Fortelny RH, 2014, SURG ENDOSC, V28, P735, DOI 10.1007/s00464-013-3251-6
   Gasser E, 2021, FRONT SURG, V8, DOI 10.3389/fsurg.2021.632929
   Gauzit R, 2009, SURG INFECT, V10, P119, DOI 10.1089/sur.2007.092
   Horwood J, 2009, ANN ROY COLL SURG, V91, P681, DOI 10.1308/003588409X12486167520993
   Hougaard HT, 2014, INT WOUND J, V11, P13, DOI 10.1111/iwj.12281
   Hutchins RR, 2004, WORLD J SURG, V28, P137, DOI 10.1007/s00268-003-7067-8
   Hynninen M, 2008, LANGENBECK ARCH SURG, V393, P81, DOI 10.1007/s00423-007-0160-y
   Jannasch O, 2018, POL J SURG, V90, P27, DOI 10.5604/01.3001.0012.1751
   Kafka-Ritsch R, 2020, WORLD J SURG, V44, P4098, DOI 10.1007/s00268-020-05762-1
   Kafka-Ritsch R, 2012, WORLD J SURG, V36, P1765, DOI 10.1007/s00268-012-1586-0
   Kao AM, 2019, J TRAUMA ACUTE CARE, V87, P623, DOI 10.1097/TA.0000000000002345
   Kirkpatrick AW, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0183-4
   Kirkpatrick AW, 2015, ANN SURG, V262, P38, DOI 10.1097/SLA.0000000000001095
   Kubiak BD, 2010, SHOCK, V34, P525, DOI 10.1097/SHK.0b013e3181e14cd2
   Lamme B, 2004, BJS-BRIT J SURG, V91, P1046, DOI 10.1002/bjs.4517
   Loftus TJ, 2017, J TRAUMA ACUTE CARE, V82, P345, DOI 10.1097/TA.0000000000001283
   Malangoni Mark A, 2006, World J Emerg Surg, V1, P25, DOI 10.1186/1749-7922-1-25
   Mintziras I, 2016, LANGENBECK ARCH SURG, V401, P619, DOI 10.1007/s00423-016-1443-y
   Müller V, 2020, ACTA CHIR BELG, V120, P179, DOI 10.1080/00015458.2019.1576448
   Mutafchiyski VM, 2016, J ROY ARMY MED CORPS, V162, P30, DOI 10.1136/jramc-2014-000386
   OHMANN C, 1993, EUR J SURG, V159, P267
   Olejnik J, 2007, BRATISL MED J, V108, P320
   Pieracci FM, 2007, SCAND J SURG, V96, P184, DOI 10.1177/145749690709600302
   Pliakos I, 2012, AM SURGEON, V78, P957
   Pliakos I, 2010, SURGERY, V148, P947, DOI 10.1016/j.surg.2010.01.021
   Poillucci G, 2021, EUR J TRAUMA EMERG S, V47, P1819, DOI 10.1007/s00068-020-01379-0
   Rajabaleyan P, 2022, WORLD J EMERG SURG, V17, DOI 10.1186/s13017-022-00427-x
   Raki M., 2005, Croatian Medical Journal, V46, P883
   Roberts DJ, 2016, ANN SURG, V263, P1018, DOI 10.1097/SLA.0000000000001347
   Robledo Felipe A, 2007, Surg Infect (Larchmt), V8, P63, DOI 10.1089/sur.2006.8.016
   Rosenzweig M, 2020, SURG INFECT, V21, P665, DOI 10.1089/sur.2019.272
   Ross JT, 2018, BMJ-BRIT MED J, V361, DOI 10.1136/bmj.k1407
   ROTONDO MF, 1993, J TRAUMA, V35, P375, DOI 10.1097/00005373-199309000-00008
   Sartelli M, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0141-6
   Sartelli M, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0132-7
   Sartelli M, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0055-0
   Sartelli M, 2014, WORLD J EMERG SURG, V9, DOI 10.1186/1749-7922-9-37
   Schmelzle M, 2010, DIGEST SURG, V27, P272, DOI 10.1159/000314609
   Tao QS, 2014, GASTROENT RES PRACT, V2014, DOI 10.1155/2014/245182
   Tartaglia D, 2021, UPDATES SURG, V73, P1975, DOI 10.1007/s13304-021-01012-8
   Tolonen M, 2017, J TRAUMA ACUTE CARE, V82, P1100, DOI 10.1097/TA.0000000000001452
   Tolonen M, 2016, LANGENBECK ARCH SURG, V401, P611, DOI 10.1007/s00423-016-1454-8
   Tridente A, 2014, INTENS CARE MED, V40, P202, DOI 10.1007/s00134-013-3158-7
   van Ruler O, 2007, JAMA-J AM MED ASSOC, V298, P865, DOI 10.1001/jama.298.8.865
   van Ruler O, 2007, CRIT CARE MED, V35, P468, DOI 10.1097/01.CCM.0000253399.03545.2D
   von Elm E, 2007, PLOS MED, V4, P1623, DOI [10.1371/journal.pmed.0040296, 10.1371/journal.pmed.0040297]
   Wacha H, 1999, LANGENBECK ARCH SURG, V384, P24, DOI 10.1007/s004230050169
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
NR 64
TC 4
Z9 7
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD FEB
PY 2025
VL 49
IS 2
BP 387
EP 400
DI 10.1002/wjs.12472
EA JAN 2025
PG 14
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA W0Z9Z
UT WOS:001395128800001
PM 39794299
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Cangel, U
   Sirekbasan, S
   Polat, E
AF Cangel, Ugur
   Sirekbasan, Serhat
   Polat, Erdal
TI Comparison of Larval Therapy and Vacuum-Assisted Closure Therapy after
   Revascularization in Peripheral Artery Disease Patients with Ischemic
   Wounds
SO EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
LA English
DT Article
ID MAGGOT DEBRIDEMENT THERAPY; CARDIOVASCULAR-DISEASE; PRESSURE; FOOT
AB Objective. Even for very successful peripheral revascularization therapy, treatment is not complete until the ulcerative, gangrenous, and infected wound is closed. This study was performed and compared the outcomes of vacuum-assisted closure (VAC) and maggot debridement therapy (MDT) following peripheral revascularization to accelerate the wound healing process. Methods. We did a prospective randomized clinical trial between January 1, 2014, and June 21, 2019. This study included 72 patients (63 males and nine females). Balloon angioplasty was performed in 21 patients (29.2%), peripheral bypass in 39 (54.2%), and both balloon angioplasty and revascularization (hybrid) surgery in 12 (16.7%). Thirty-three patients (45.8%) received 15 VAC therapy sessions for a month. Therapy progress was monitored at 48 h intervals, and wound debridement was performed. Thirtynine patients (54.2%) received an average of six larval therapy sessions for a month. Groups were compared with the X-2 test, and a statistically significant difference was found (P < 0.001). Results. In the VAC therapy group (n = 33), 14 patients (42.4%) had their feet amputated, 5 (15.1%) had a toe amputated, and 4 (12.1%) had all of their toes amputated. A skin graft was performed on four patients (12.1%) who developed granulation tissue. The wounds of six patients (18.2%) undergoing VAC therapy healed. In the larval therapy group (n = 39), the wounds healed in 36 patients (92.3%), and 3 (7.7%) had a toe amputated. Conclusion. Larval therapy was shown to be more effective than VAC therapy for the treatment of postrevascularization ischemic wounds. Thus, larval therapy can be used as an effective biological treatment method when major amputation is not required.
C1 [Cangel, Ugur] Bahcesehir Univ, Med Fac, Dept Cardiovasc Surg, Istanbul, Turkey.
   [Sirekbasan, Serhat] Cankiri Karatekin Univ, Eldivan Vocat Sch Hlth Serv, Dept Med Lab Tech, Cankiri, Turkey.
   [Polat, Erdal] Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Med Microbiol, Istanbul, Turkey.
C3 Bahcesehir University; Cankiri Karatekin University; Istanbul University
   - Cerrahpasa
RP Sirekbasan, S (通讯作者)，Cankiri Karatekin Univ, Eldivan Vocat Sch Hlth Serv, Dept Med Lab Tech, Cankiri, Turkey.
EM serhatsirekbasan@gmail.com
RI Polat, Erdal/D-7602-2019; Sirekbasan, Serhat/Q-1093-2018
OI Cangel, Uğur/0009-0007-4941-3438; Sirekbasan, Serhat/0000-0001-7967-3539
CR Aiello A, 2014, NUTR METAB CARDIOVAS, V24, P355, DOI 10.1016/j.numecd.2013.12.007
   Bonn D, 2000, LANCET, V356, P1174, DOI 10.1016/S0140-6736(05)72870-1
   Brin Y S, 2007, J Wound Care, V16, P111
   Campbell N, 2014, OSTOMY WOUND MANAG, V60, P16
   Fang R, 2010, J TRAUMA, V69, pS140, DOI 10.1097/TA.0b013e3181e452a2
   Huberman L, 2007, J Wound Care, V16, P123
   Huberman L, 2007, MED VET ENTOMOL, V21, P127, DOI 10.1111/j.1365-2915.2007.00668.x
   Igari Kimihiro, 2013, Ann Vasc Dis, V6, P145, DOI 10.3400/avd.oa.13-00036
   Joseph E, 2000, WOUNDS, V12, P60
   KANNEL WB, 1979, JAMA-J AM MED ASSOC, V241, P2035, DOI 10.1001/jama.241.19.2035
   Maeda TM, 2014, CLIN EXP DERMATOL, V39, P911, DOI 10.1111/ced.12454
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mumcuoglu K Y, 2001, Am J Clin Dermatol, V2, P219
   Mumcuoglu KY, 1998, DIABETES CARE, V21, P2030, DOI 10.2337/diacare.21.11.2030
   Mumcuoglu KY, 2001, J MED ENTOMOL, V38, P161, DOI 10.1603/0022-2585-38.2.161
   Petrie JR, 2018, CAN J CARDIOL, V34, P575, DOI 10.1016/j.cjca.2017.12.005
   Robert N, 2017, ORTHOP TRAUMATOL-SUR, V103, pS99, DOI 10.1016/j.otsr.2016.04.018
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Sherman RA, 1997, PLAST RECONSTR SURG, V100, P451, DOI 10.1097/00006534-199708000-00029
   Sherman RA, 2002, WOUND REPAIR REGEN, V10, P208, DOI 10.1046/j.1524-475X.2002.10403.x
   Sinha K, 2013, ADV ORTHOP, V2013, DOI 10.1155/2013/245940
   Steiert AE, 2009, J PLAST RECONSTR AES, V62, P675, DOI 10.1016/j.bjps.2007.09.041
   Thackham JA, 2008, WOUND REPAIR REGEN, V16, P321, DOI 10.1111/j.1524-475X.2008.00372.x
   Thomas S., 1998, J WOUND CARE, V7, P521
   VISTNES LM, 1981, SURGERY, V90, P835
NR 25
TC 3
Z9 4
U1 0
U2 3
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1741-427X
EI 1741-4288
J9 EVID-BASED COMPL ALT
JI Evid.-based Complement Altern. Med.
PD MAR 29
PY 2022
VL 2022
AR 8148298
DI 10.1155/2022/8148298
PG 6
WC Integrative & Complementary Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Integrative & Complementary Medicine
GA 5L1XY
UT WOS:000870210700007
PM 35392647
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Park, S
   Son, BS
   Park, H
   Kim, HJ
   Park, SJ
   Kim, HY
AF Park, Seyeon
   Son, Bong Soo
   Park, Hyeonsoo
   Kim, Hye-Jin
   Park, Soon Ji
   Kim, Hee Young
TI Endoscopic vacuum therapy for cervical leakage following esophagectomy
   under monitored anesthesia care: a case report
SO ANNALS OF PALLIATIVE MEDICINE
LA English
DT Article
DE Anastomotic leak; anesthesia; case report; endoscopy; esophagectomy;
   vacuum assisted closure (VAC)
AB Although esophagectomy is a standard treatment for esophageal cancer, anastomotic leak after esophagectomy is a relatively common complication and its incidence is 10-25% for cervical anastomosis. Endoscopic vacuum therapy (EVT) is a feasible primary treatment of esophageal perforations and leaks. Currently, there are no anesthesia guidelines for EVT, however, it is usually performed under general anesthesia with endotracheal intubation, especially for cervical EVT. Here, we report a successful EVT under monitored anesthesia care (MAC) without any complication, which doesn't need to intubate the patient. A 64-year-old male with upper esophageal cancer underwent an Ivor-Lewis operation with cervical anastomosis. Vacuum assisted closure (VAC) was performed for cervical leak under general anesthesia, but there was no further improvement. Although EVT was attempted under sedation with midazolam in an endoscopy room, the procedure was discontinued because of desaturation. Furthermore, the thoracic surgeon was concerned about the possibility of dyspnea and hypoxia even after the procedure. EVT was scheduled under MAC at the request of a thoracic surgeon and medical doctor, as EVT was expected to lead to patient discomfort and difficult airway. EVT was performed successfully with no respiratory depression or patient movement using target controlled infusion with 2% propofol and remifentanil. The patient was discharged on the 78th POD without any other complications. EVT for cervical leak after esophagectomy can be successfully performed with MAC, and understanding the general condition of the patient, cooperation with the patient and the surgeon, and providing continuous oxygen supply to the patient are necessary for a successful procedure under MAC.
C1 [Park, Seyeon; Park, Hyeonsoo; Kim, Hye-Jin; Park, Soon Ji; Kim, Hee Young] Pusan Natl Univ, Dept Anesthesia & Pain Med, Yangsan Hosp, 20 Geumo Ro, Yangsan 50612, South Korea.
   [Son, Bong Soo] Pusan Natl Univ, Dept Thorac & Cardiovasc Surg, Yangsan Hosp, Yangsan, South Korea.
C3 Pusan National University; Pusan National University Hospital; Pusan
   National University; Pusan National University Hospital
RP Kim, HY (通讯作者)，Pusan Natl Univ, Dept Anesthesia & Pain Med, Yangsan Hosp, 20 Geumo Ro, Yangsan 50612, South Korea.
EM anekhy@gmail.com
RI Kim, Hee Young/HII-5042-2022
OI 박, 세연/0000-0001-7183-1811
FU Pusan National University Yangsan Hospital
FX This work was supported by a 2020 research grant from Pusan National
   University Yangsan Hospital.
CR Alanezi Khaled, 2004, Ann Thorac Cardiovasc Surg, V10, P71
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Hwang JJ, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000003416
   Kuehn F, 2017, SURG ENDOSC, V31, P3449, DOI 10.1007/s00464-016-5404-x
   Lerut T, 2002, DIGEST SURG, V19, P92, DOI 10.1159/000052018
   Miller RD, 2011, CHOICE ANESTHETIC TE, V6TH, P194
   Still S, 2018, ANN THORAC CARDIOVAS, V24, P173, DOI 10.5761/atcs.oa.17-00107
   Turkyilmaz A, 2009, DIS ESOPHAGUS, V22, P119, DOI 10.1111/j.1442-2050.2008.00866.x
NR 8
TC 0
Z9 0
U1 0
U2 1
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2224-5820
EI 2224-5839
J9 ANN PALLIAT MED
JI Ann. Pallliat. Med.
PD APR
PY 2021
VL 10
IS 4
BP 4906
EP 4910
DI 10.21037/apm-20-1394
PG 5
WC Health Care Sciences & Services
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Health Care Sciences & Services
GA RW5PK
UT WOS:000646574100124
PM 33183021
OA gold
DA 2026-07-24
ER

PT J
AU Vos, RJ
   van Putte, BP
   Sonker, U
   Kloppenburg, GTL
AF Vos, Roemer J.
   van Putte, Bart P.
   Sonker, Uday
   Kloppenburg, Geoffrey T. L.
TI Primary closure using Redon drains for the treatment of post-sternotomy
   mediastinitis
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Mediastinitis; Infection; Redon drainage; Sternotomy
ID VACUUM-ASSISTED CLOSURE; POSTSTERNOTOMY MEDIASTINITIS; POSTOPERATIVE
   MEDIASTINITIS; CONVENTIONAL TREATMENT; RISK-FACTORS; THERAPY;
   DEBRIDEMENT; INFECTIONS; CATHETERS
AB OBJECTIVES: Post-sternotomy mediastinitis is a severe complication of open heart surgery resulting in prolonged hospital stay and increased mortality. Vacuum-assisted closure is commonly used as treatment for post-sternotomy mediastinitis, but has some disadvantages. Primary closure over high vacuum suction Redon drains previously has shown to be an alternative approach with promising results. We report our short-and long-term results of Redon therapy-treated mediastinitis.
   METHODS: We performed a retrospective analysis of 124 patients who underwent primary closure of the sternum over Redon drains as treatment for post-sternotomy mediastinitis in Amphia Hospital (Breda, Netherlands) and St. Antonius Hospital (Nieuwegein, Netherlands). Patient characteristics, preoperative risk factors and procedure-related variables were analysed. Duration of therapy, hospital stay, treatment failure and mortality as well as C-reactive protein and blood leucocyte counts on admission and at various time intervals during hospital stay were determined.
   RESULTS: Mean age of patients was 68.7 +/- 11.0 years. In 77.4%, the primary surgery was coronary artery bypass grafting. Presentation of mediastinitis was 15.2 +/- 9.8 days after surgery. Duration of Redon therapy was 25.9 +/- 18.4 days. Hospital stay was 32.8 +/- 20.7 days. Treatment failure occurred in 8.1% of patients. In-hospital mortality was 8.9%. No risk factors were found for mortality or treatment failure. The median follow-up time was 6.6 years. One-and 5-year survivals were 86 and 70%, respectively.
   CONCLUSIONS: Primary closure using Redon drains is a feasible, simple and efficient treatment modality for post-sternotomy mediastinitis.
C1 [Vos, Roemer J.; Sonker, Uday; Kloppenburg, Geoffrey T. L.] St Antonius Hosp, Dept Cardiothorac Surg, NL-3435 CM Nieuwegein, Netherlands.
   [van Putte, Bart P.] Amphia Hosp, Dept Cardiothorac Surg, Breda, Netherlands.
C3 St. Antonius Hospital Utrecht; Amphia Hospital
RP Vos, RJ (通讯作者)，St Antonius Hosp, Dept Cardiothorac Surg, Koekoekslaan 1, NL-3435 CM Nieuwegein, Netherlands.
EM roemervos@gmail.com
OI Vos, Roemer/0000-0002-2511-988X
CR Atkins BZ, 2011, AM J SURG, V202, P565, DOI 10.1016/j.amjsurg.2011.06.013
   Berg HF, 2000, ANN THORAC SURG, V70, P924, DOI 10.1016/S0003-4975(00)01524-1
   Calvat S, 1996, ANN THORAC SURG, V61, P195, DOI 10.1016/0003-4975(95)00921-3
   Dessap AM, 2011, CLIN MICROBIOL INFEC, V17, P292, DOI 10.1111/j.1469-0691.2010.03197.x
   Doss M, 2002, EUR J CARDIO-THORAC, V22, P934, DOI 10.1016/S1010-7940(02)00594-8
   DURANDY Y, 1989, J THORAC CARDIOV SUR, V97, P282
   Fuchs U, 2005, ANN THORAC SURG, V79, P526, DOI 10.1016/j.athoracsur.2004.08.032
   HORAN TC, 1992, AM J INFECT CONTROL, V20, P271, DOI 10.1016/S0196-6553(05)80201-9
   Kirsch M, 2001, ANN THORAC SURG, V71, P1580, DOI 10.1016/S0003-4975(01)02452-3
   Luckraz H, 2003, J THORAC CARDIOV SUR, V125, P301, DOI 10.1067/mtc.2003.74
   Risnes I, 2010, ANN THORAC SURG, V89, P1502, DOI 10.1016/j.athoracsur.2010.02.038
   Sartipy U, 2006, ANN THORAC SURG, V82, P1110, DOI 10.1016/j.athoracsur.2006.01.060
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Trouillet JL, 2005, J THORAC CARDIOV SUR, V129, P518, DOI 10.1016/j.jtcvs.2004.07.027
NR 16
TC 7
Z9 14
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
EI 1569-9285
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD JAN
PY 2014
VL 18
IS 1
BP 33
EP 37
DI 10.1093/icvts/ivt385
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA AB8II
UT WOS:000332033200010
PM 24071369
DA 2026-07-24
ER

PT J
AU Hämäläinen, E
   Laurikka, J
   Huhtala, H
   Järvinen, O
AF Hamalainen, E.
   Laurikka, J.
   Huhtala, H.
   Jarvinen, O.
TI Vacuum assistance therapy as compared to early reconstructive treatment
   in deep sternal wound infection
SO SCANDINAVIAN JOURNAL OF SURGERY
LA English
DT Article
DE Cardiac surgery; deep sternal wound infection; DSWI; mediastinitis;
   pressure therapy; candida
ID CLOSURE THERAPY; MEDIASTINITIS; IMPACT
AB Background and Aims:
   Deep sternal wound infection is a major concern after cardiac surgery. This study describes the incidence of postoperative deep sternal wound infections after cardiac surgery and compares two available treatment modalities.
   Materials and Methods:
   In Tampere University Hospital, 7973 open heart operations were performed between 2007 and 2016. Patients treated for a postoperative deep sternal wound infection were categorized in two groups based on treatment: revision surgery with early reconstruction (revision group; 74 patients) or vacuum-assisted closure treatment (VAC group; 55 patients). The end points in comparisons were overall mortality and hospitalization time.
   Results:
   A total of 129 patients (1.6%) developed a postoperative deep sternal wound infection. The 30-day mortality rates were 8.1% and 3.6%, the 90-day mortality rates were 15.5% and 18.2%, and the 1-year mortality rates were 17.6% and 23.6% for the revision and VAC group, respectively. There was no statistically significant difference in mortality rates. The hospital stay was 18 days in the revision group and 38 days in the VAC group (p < 0.001). The secondary intensive care unit stay was longer in the VAC group (median 1 vs 4, p = 0.011). The most common pathogens isolated in the first reoperation were coagulase-negative staphylococci (33.8% and 41.8%, respectively; p = 0.366), and positive candida findings were more common in the VAC group (4.1% vs 37.0 %, p < 0.001).
   Conclusion:
   Vacuum-assisted closure treatment induces an inferior outcome in terms of fungal infections, treatment times, and the number of reoperations.
C1 [Hamalainen, E.; Laurikka, J.] Tampere Univ, Fac Med & Hlth Technol, Arvo Ylpon Katu 34, Tampere 33500, Finland.
   [Laurikka, J.; Jarvinen, O.] Tampere Heart Hosp, Dept Cardiothorac Surg, Tampere, Finland.
   [Huhtala, H.] Tampere Univ, Fac Social Sci, Tampere, Finland.
C3 Tampere University; Tampere University
RP Hämäläinen, E (通讯作者)，Tampere Univ, Fac Med & Hlth Technol, Arvo Ylpon Katu 34, Tampere 33500, Finland.
EM eero.hamalainen@tuni.fi
RI ; LAURIKKA, Jari/F-2010-2014
OI Hämäläinen, Eero/0000-0003-1230-8654; LAURIKKA,
   Jari/0000-0001-7253-6048; Huhtala, Heini/0000-0003-1372-430X
CR Baillot R, 2010, EUR J CARDIO-THORAC, V37, P880, DOI 10.1016/j.ejcts.2009.09.023
   Deniz H, 2012, J CARDIOTHORAC SURG, V7, DOI 10.1186/1749-8090-7-67
   Eklund AM, 2006, ANN THORAC SURG, V82, P1784, DOI 10.1016/j.athoracsur.2006.05.097
   Finkelstein R, 2005, AM J INFECT CONTROL, V33, P450, DOI 10.1016/j.ajic.2005.07.002
   Indja B, 2017, HEART LUNG CIRC, V26, P779, DOI 10.1016/j.hlc.2016.12.010
   Lola I, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-151
   Merrill WH, 2004, ANN THORAC SURG, V78, P608, DOI 10.1016/j.athoracsur.2004.02.089
   Risnes I, 2014, INT WOUND J, V11, P177, DOI 10.1111/j.1742-481X.2012.01060.x
   Segers Patrique, 2005, Interact Cardiovasc Thorac Surg, V4, P555, DOI 10.1510/icvts.2005.112714
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Speir AM, 2009, ANN THORAC SURG, V88, P40, DOI 10.1016/j.athoracsur.2009.03.076
   Swenne CL, 2007, SCAND CARDIOVASC J, V41, P255, DOI 10.1080/14017430701283856
   Tocco MP, 2009, EUR J CARDIO-THORAC, V35, P833, DOI 10.1016/j.ejcts.2008.12.036
   WOUTERS R, 1994, TEX HEART I J, V21, P183
NR 14
TC 15
Z9 18
U1 0
U2 4
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1457-4969
EI 1799-7267
J9 SCAND J SURG
JI Scand. J. Surg.
PD JUN
PY 2021
VL 110
IS 2
SI SI
BP 248
EP 253
AR 1457496920979289
DI 10.1177/1457496920979289
EA DEC 2020
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA TE4GX
UT WOS:000599898500001
PM 33327852
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Hutan, M
   Sen, HM
   Skultety, J
   Sekac, J
   Koudelka, P
   Prochotsky, A
   Yaghi, A
   Labas, P
AF Hutan, M., Jr.
   Sen, Hutan M.
   Skultety, J.
   Sekac, J.
   Koudelka, P.
   Prochotsky, A.
   Yaghi, A.
   Labas, P.
TI Use of intraabdominal VAC (Vacuum Assisted Closure) lowers mortality and
   morbidity in patients with open abdomen
SO BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
LA English
DT Article
DE VAC; open abdomen; Kern laparostomy; SMAC; dynamic compression sutures
AB Objective: Authors compare two groups of patients with open abdomen. The objective is to compare and evaluate two treatment modalities, namely Kern laparostomy and vacuum-assisted closure in terms of mortality, closure of abdominal wound, and fistula management, all these stratified by BMI and CRP.
   Background: Open abdomen can be considered a "patient salvage technique", used in patients with abdominal sepsis, as well as in patients with abdominal compartment syndrome, and in damage control surgery. Various management techniques are known, of which Kern laparostomy is most widely used. Newer techniques using negative pressure have emerged, still waiting for their wider acceptance and use. The authors present their study, in which they compare Kern laparostomy and intraabdominal VAC in patients with open abdomen.
   Material and methods: Study consists of 44 patients treated at the authors clinics, while group KERN consisted of patients managed by Kern laparostomy, and group VAC was managed by intraabdominal VAC. The groups were compared in terms of mortality, abdominal closure, appearance of enteroatmospheric fistulas, primary closure of fistulas, and possibility of diversion of enteral contents. All outputs were stratified by CRP (C-reactive protein) and BMI (Body Mass Index).
   Results: In VAC group, a significant decrease in mortality was seen, as well as significantly higher closure of abdominal wall, and significantly higher possibility of diversion of enteral content from fistulas. No statistically significant findings were observed in stratification with CRP and BMI.
   Conclusion: Intraabdominal VAC offers patients lower morbidity and mortality and should be defined as a treatment of choice in patients with open abdomen (Tab. 4, Fig. 3, Ref. 15). Full Text in PDF www.elis.sk.
C1 [Hutan, M., Jr.; Skultety, J.; Sekac, J.; Koudelka, P.; Prochotsky, A.] Comenius Univ, Univ Hosp Bratislava, Hosp St Cyril & Methodius, Sch Med,Surg Clin 2, SK-85107 Bratislava, Slovakia.
   [Sen, Hutan M.] Comenius Univ, Univ Hosp Bratislava, Hosp Ruzinov, Sch Med,Surg Clin 4, SK-85107 Bratislava, Slovakia.
   [Yaghi, A.] Hosp Ruzinov, Univ Hosp Bratislava, Anaesthesiol & Intens Med Clin, Bratislava, Slovakia.
   [Labas, P.] Comenius Univ, Univ Hosp Bratislava, Hosp Stare Mesto, Sch Med,Surg Clin 1, SK-85107 Bratislava, Slovakia.
C3 Comenius University Bratislava; Slovak Medical University Bratislava;
   Slovak Medical University Bratislava; Comenius University Bratislava;
   Slovak Medical University Bratislava; Comenius University Bratislava;
   Slovak Medical University Bratislava
RP Hutan, M (通讯作者)，Comenius Univ, Univ Hosp Bratislava, Hosp St Cyril & Methodius, Sch Med,Surg Clin 2, Antolska 11, SK-85107 Bratislava, Slovakia.
EM matohuto@yahoo.com
CR Al-Khoury G, 2008, J AM COLL SURGEONS, V206, P397, DOI 10.1016/j.jamcollsurg.2007.07.027
   Arigon JP, 2008, J CHIR-PARIS, V145, P252, DOI 10.1016/S0021-7697(08)73755-4
   Björck M, 2009, WORLD J SURG, V33, P1154, DOI 10.1007/s00268-009-9996-3
   Caro A, 2011, INT WOUND J, V211
   de Costa A, 2006, ANZ J SURG, V76, P356, DOI 10.1111/j.1445-2197.2006.03638.x
   Evenson RA, 2006, CHIRURG, V77, P594, DOI 10.1007/s00104-006-1207-2
   Goverman J, 2006, J TRAUMA, V60, P428, DOI 10.1097/01.ta.0000203588.66012.c4
   Hutan M, 2010, BRATISL MED J, V111, P461
   Joyce MR, 2006, CURR PROB SURG, V46, P384
   KERN E, 1983, CHIRURG, V54, P306
   Olejnik J, 2008, HEPATO-GASTROENTEROL, V55, P315
   Schachtrupp A, 2002, Hernia, V6, P155
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   Shaikh IA, 2010, COLORECTAL DIS, V12, P931, DOI 10.1111/j.1463-1318.2009.01929.x
   Stremitzer S, 2011, INT J COLORECT DIS
NR 15
TC 7
Z9 7
U1 0
U2 3
PU COMENIUS UNIV
PI BRATISLAVA I
PA SCH MEDICINE, SPITALSKA 24, BRATISLAVA I, SK-813 72, SLOVAKIA
SN 0006-9248
EI 1336-0345
J9 BRATISL MED J
JI Bratisl. Med. J.
PY 2013
VL 114
IS 8
BP 451
EP 454
DI 10.4149/BLL_2013_094
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 297QL
UT WOS:000330269900005
PM 23944619
OA Bronze
DA 2026-07-24
ER

PT J
AU Hakim, S
   Ahmed, K
   El-Menyar, A
   Jabbour, G
   Peralta, R
   Nabir, S
   Mekkodathil, A
   Abdelrahman, H
   Al-Hassani, A
   Al-Thani, H
AF Hakim, Suhail
   Ahmed, Khalid
   El-Menyar, Ayman
   Jabbour, Gaby
   Peralta, Ruben
   Nabir, Syed
   Mekkodathil, Ahammed
   Abdelrahman, Husham
   Al-Hassani, Ammar
   Al-Thani, Hassan
TI Patterns and management of degloving injuries: a single national level 1
   trauma center experience
SO WORLD JOURNAL OF EMERGENCY SURGERY
LA English
DT Article
DE Degloving; Soft tissue injury; Debridement; Management; Trauma
ID VACUUM-ASSISTED CLOSURE; MOREL-LAVALLEE LESION
AB Background: Degloving soft tissue injuries (DSTIs) are serious surgical conditions. We aimed to evaluate the pattern, management and outcome of DSTIs in a single institute.
   Methods: A retrospective analysis was performed for patients admitted with DSTIs from 2011 to 2013. Presentation, management and outcomes were analyzed according to the type of DSTI.
   Results: Of 178 DSTI patients, 91 % were males with a mean age of 30.5 +/- 12.8. Three-quarter of cases was due to traffic-related injuries. Eighty percent of open DSTI cases were identified. Primary debridement and closure (62.9 %) was the frequent intervention used. Intermediate closed drainage under ultrasound guidance was performed in 7 patients; however, recurrence occurred in 4 patients who underwent closed serial drainage for recollection and ended with a proper debridement with or without vacuum assisted closure (VAC). Closed DSTIs were mainly seen in the lower extremity and back region and initially treated with conservative management as compared to open DSTIs. Infection and skin necrosis were reported in 9 cases only. Open DSTIs were more likely involving head and neck region and being treated by primary debridement/suturing and serial debridement/washout with or without VAC. All-cause DSTI mortality was 9 % that was higher in the closed DSTIs (19.4 vs 6.3 %; p = 0.01).
   Conclusion: The incidence of DSTIs is 4 % among trauma admissions over 3 years, with a greater predilection to males and young population. DSTIs are mostly underestimated particularly in the closed type that are usually missed at the initial presentation and associated with poor outcomes. Treatment guidelines are not well established and therefore further studies are warranted.
C1 [Hakim, Suhail; Ahmed, Khalid; Jabbour, Gaby; Peralta, Ruben; Abdelrahman, Husham; Al-Hassani, Ammar; Al-Thani, Hassan] Hamad Gen Hosp, Trauma Surg Sect, Doha, Qatar.
   [El-Menyar, Ayman; Mekkodathil, Ahammed] Hamad Gen Hosp, Trauma Surg Sect, Clin Res, Doha, Qatar.
   [El-Menyar, Ayman] Weill Cornell Med Coll, Clin Med, Doha, Qatar.
   [Nabir, Syed] Hamad Gen Hosp, Dept Radiol, Doha, Qatar.
C3 Hamad Medical Corporation; Hamad General Hospital; Hamad Medical
   Corporation; Hamad General Hospital; Qatar Foundation (QF); Weill
   Cornell Medical College Qatar; Hamad Medical Corporation; Hamad General
   Hospital
RP El-Menyar, A (通讯作者)，Hamad Gen Hosp, Trauma Surg Sect, Clin Res, Doha, Qatar.; El-Menyar, A (通讯作者)，Weill Cornell Med Coll, Clin Med, Doha, Qatar.
EM aymanco65@yahoo.com
RI Mekkodathil, Ahammed Abdulla/E-9629-2018; El-Menyar, Ayman/F-6734-2015;
   Peralta, Ruben/Y-4605-2018
OI Mekkodathil, Ahammed Abdulla/0000-0001-8431-8937; El-Menyar,
   Ayman/0000-0003-2584-953X; AHMED, KHALID/0000-0003-3576-0555; Peralta,
   Ruben/0000-0003-2817-0194
CR Antoniou D., 2005, Eur. J. Trauma, V31, P593, DOI DOI 10.1007/S00068-005-1059-3
   Dini M, 2012, INJURY, V43, P957, DOI 10.1016/j.injury.2011.03.020
   El-Menyar A, 2015, TRAFFIC INJ PREV, V13, P1
   Gilbert BC, 2004, AM J ROENTGENOL, V182, P1347, DOI 10.2214/ajr.182.5.1821347
   Gummalla KM, 2014, ULUS TRAVMA ACIL CER, V20, P63, DOI 10.5505/tjtes.2014.88403
   Hak DJ, 1997, J TRAUMA, V42, P1046, DOI 10.1097/00005373-199706000-00010
   HUDSON DA, 1992, PLAST RECONSTR SURG, V89, P853, DOI 10.1097/00006534-199205000-00013
   Khan Amir Taimur, 2004, J Coll Physicians Surg Pak, V14, P416
   Kottmeier SA, 1996, CLIN ORTHOP RELAT R, P46
   Krishnamoorthy R, 2011, Indian J Plast Surg, V44, P227, DOI 10.4103/0970-0358.85344
   Latifi R, 2013, SOJ Surg, V1, P01
   Latifi Rifat, 2014, J Emerg Trauma Shock, V7, P228, DOI 10.4103/0974-2700.136870
   Meara JG, 1999, ANN PLAS SURG, V42, P589, DOI 10.1097/00000637-199906000-00002
   Mello Daniel Francisco, 2015, Rev. Col. Bras. Cir., V42, P143, DOI [10.1590/0100-69912015003003, 10.1590/0100-69912015003003]
   Milcheski Dimas André, 2010, Rev. Col. Bras. Cir., V37, P199
   Morris Melanie, 2009, J Trauma, V67, pE121, DOI 10.1097/TA.0b013e31803420be
   Nickerson TP, 2014, J TRAUMA ACUTE CARE, V76, P493, DOI 10.1097/TA.0000000000000111
   Wojcicki Piotr, 2011, Pol Przegl Chir, V83, P276, DOI 10.2478/v10035-011-0043-3
   Wong LK, 2006, SOUTH MED J, V99, P628, DOI 10.1097/01.smj.0000217111.35160.09
   Yan HD, 2013, J TRAUMA ACUTE CARE, V74, P604, DOI 10.1097/TA.0b013e31827d5e00
NR 20
TC 24
Z9 37
U1 0
U2 7
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-7922
J9 WORLD J EMERG SURG
JI World J. Emerg. Surg.
PD JUL 27
PY 2016
VL 11
AR 35
DI 10.1186/s13017-016-0093-2
PG 8
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA DT8OY
UT WOS:000381751800001
PM 27468300
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Palmen, M
   van Breugel, NAM
   Geskes, GG
   van Belle, A
   Swennen, JMH
   Drijkoningen, AHM
   van der Hulst, RR
   Maessen, JG
AF Palmen, Meindert
   van Breugel, Nathalie A. M.
   Geskes, Gijs G.
   van Belle, Arne
   Swennen, Jos M. H.
   Drijkoningen, Andre H. M.
   van der Hulst, Rene R.
   Maessen, Jos G.
TI Open Window Thoracostomy Treatment of Empyema Is Accelerated by
   Vacuum-Assisted Closure
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID WOUNDS
AB Background. Recurrent thoracic empyema in the presence of residual lung tissue can be treated with an open window thoracostomy (OWT). Vacuum-assisted closure (VAC) of these large thoracic defects is a novel option.
   Methods. Nineteen patients with residual lung tissue received an OWT for treatment of recurrent thoracic empyema. In this retrospective case series, 8 patients (aged 58 +/- 20 years, all male) were treated conventionally, and 11 patients (aged 53 +/- 17 years, 8 male) were treated with VAC.
   Results. The application of the VAC system resulted in rapid debridement of the thoracic cavity and reexpansion of the residual lung tissue. The duration of OWT and VAC therapy was 39 +/- 17 and 31 +/- 19 days, respectively. All 11 patients were amenable for subsequent closure using pedicled muscular flaps. In 2 patients, VAC therapy alone resulted in complete closure of the OWT. The average duration of follow-up was 46 +/- 19 months. All patients, except 1, have recovered well. One patient died of nonpulmonary causes. In the non-VAC group (n = 8), the OWT was managed conventionally by application of saline-soaked gauzes. In 2 patients, the OWT was eventually closed using pedicled muscular flaps (after 75 and 440 days, respectively). Four patients died of OWT-related complications (1 bleeding, 3 recurrent infections) during follow-up; 1 patient died of a cause unrelated to OWT. The average duration of OWT was 933 +/- 1,422 days.
   Conclusions. When compared with conventional management of OWT, VAC therapy accelerates wound healing and improves reexpansion of residual lung tissue in patients with OWT after empyema, allowing rapid surgical closure. (Ann Thorac Surg 2009;88:1131-7) (C) 2009 by The Society of Thoracic Surgeons
C1 [Maessen, Jos G.] Maastricht Univ, Med Ctr, Dept Cardiothorac Surg, NL-6202 AZ Maastricht, Netherlands.
   Maastricht Univ, Med Ctr, Dept Pulmonol, NL-6202 AZ Maastricht, Netherlands.
   Maastricht Univ, Med Ctr, Dept Plast & Reconstruct Surg, NL-6202 AZ Maastricht, Netherlands.
   Leiden Univ, Med Ctr, Dept Cardiothorac Surg, Leiden, Netherlands.
C3 Maastricht University; Maastricht University; Maastricht University;
   Leiden University - Excl LUMC; Leiden University; Leiden University
   Medical Center (LUMC)
RP Maessen, JG (通讯作者)，Maastricht Univ, Med Ctr, Dept Cardiothorac Surg, P Debeyelaan 25, NL-6202 AZ Maastricht, Netherlands.
EM j.g.maessen@mumc.nl
RI Palmen, Meindert/GYV-4054-2022
OI Palmen, Meindert/0000-0002-7213-5452
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   DESAULIERS J, 2002, CHEST SURG CLIN N AM, V12, P605
   Eloesser L, 1935, SURG GYNECOL OBSTET, V60, P1096
   Matzi V, 2007, ANN THORAC SURG, V84, P1762, DOI 10.1016/j.athoracsur.2007.05.052
   MILLER JI, 1984, ANN THORAC SURG, V38, P227, DOI 10.1016/S0003-4975(10)62243-6
   Tamas FM, 2006, WORLD J SURG, V30, P1400, DOI 10.1007/s00268-005-0691-8
   Molnar TF, 2004, ANN THORAC SURG, V77, P372, DOI 10.1016/S0003-4975(03)01399-7
   Molnar TF, 2007, EUR J CARDIO-THORAC, V32, P422, DOI 10.1016/j.ejcts.2007.05.028
   O'Connor J, 2005, ANN THORAC SURG, V79, P1196, DOI 10.1016/j.athoracsur.2004.09.041
   Palmen M, 2009, ANN THORAC SURG, V88, P1131, DOI 10.1016/j.athoracsur.2009.06.030
   Penrose CB, 1890, JAMA, V14, P264, DOI 10.1001/jama.1890.02410080012001b
   Segers P, 2006, THORAC CARDIOV SURG, V54, P289, DOI 10.1055/s-2006-924003
   Widmer MK, 2000, EUR J CARDIO-THORAC, V18, P435, DOI 10.1016/S1010-7940(00)00538-8
NR 13
TC 49
Z9 67
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD OCT
PY 2009
VL 88
IS 4
BP 1131
EP 1137
DI 10.1016/j.athoracsur.2009.06.030
PG 8
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 501NL
UT WOS:000270388500012
PM 19766795
DA 2026-07-24
ER

PT J
AU Hersh, RE
   Jack, JM
   Dahman, MI
   Morgan, RF
   Drake, DB
AF Hersh, RE
   Jack, JM
   Dahman, MI
   Morgan, RF
   Drake, DB
TI The vacuum-assisted closure device as a bridge to sternal wound closure
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article; Proceedings Paper
CT Annual Meeting of the
   Southeastern-Society-for-Plastic-and-Reconstructive-Surgeons
CY JUN 04-08, 2000
CL BERMUDA
SP SE Soc Plast & Reconstruct Surgeons
ID MUSCLE FLAPS; NEGATIVE-PRESSURE; MEDIASTINITIS; EXPERIENCE; RUPTURE;
   REPAIR
AB Sixteen patients were treated for sternal wound infections after undergoing cardiac procedures. Their management involved prompt surgical debridement and quantitative wound biopsies. At the time of the initial debridement, the Vacuum-Assisted Closure Device (V.A.C.) was placed in the open sternal wound. A subatmospheric environment was maintained by the device at a level of 75 to 150 mmHg, The V.A.C, sponge was changed every 2 to 3 days, and operative debridement was performed until quantitative biopsies showed resolution of infection or until systemic signs of sepsis had resolved. At this time the sternal wounds were closed with regional muscle flaps. Patients were excluded from the use of the device if the pleural cavity was entered during operative debridement. Fifteen of the 16 patients survived and went on to complete wound healing and discharge from the hospital (average length of stay, 16.7 days). One patient sustained a cardiac dysrhythmia during the muscle flap procedure and died, There were no complications related directly to the use of the V.A.C. It is the opinion of the authors that the V.A.C. offers several advantages over their traditional methods of treatment. They noted improvement in sternal wound stabilization during the perioperative period and a decreased need for paralysis and mechanical ventilation. Wound management was improved by avoiding the need to perform debridement or to make desiccating dressing changes to an open sternum. Moreover, they also think that this device may lessen the risk for ventricular rupture because of better control of the wound environment and markedly improved stabilization of the debrided sternal elements.
C1 Univ Virginia Hlth Syst, Dept Plast Surg, Charlottesville, VA 22911 USA.
   Univ Kentucky, Lexington, KY USA.
   Ain Shams Univ, Cairo, Egypt.
   Univ Virginia, Charlottesville, VA USA.
C3 University of Virginia; University of Virginia (UVA) Health System;
   University of Kentucky; Egyptian Knowledge Bank (EKB); Ain Shams
   University; University of Virginia
RP Drake, DB (通讯作者)，Univ Virginia Hlth Syst, Dept Plast Surg, POB 800376, Charlottesville, VA 22911 USA.
CR Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
   Argenta L, 1993, JOINT M WOUND HEAL S
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1994, 73 ANN M AM ASS PLAS
   BACKER CL, 1994, ANN THORAC SURG, V57, P797, DOI 10.1016/0003-4975(94)90179-1
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   HIGGINS RSD, 1991, ANN THORAC SURG, V52, P1161, DOI 10.1016/0003-4975(91)91302-C
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   JULIAN OC, 1957, SURGERY, V42, P753
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   LOOP FD, 1990, ANN THORAC SURG, V49, P179, DOI 10.1016/0003-4975(90)90136-T
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Schumaker Jr H.B., 1963, ARCH SURG-CHICAGO, V86, P384
   Smith LA, 1997, AM SURGEON, V63, P1102
   WEINSTEIN RA, 1976, ANN THORAC SURG, V21, P442, DOI 10.1016/S0003-4975(10)63896-9
   YUEN JC, 1991, ANN PLAS SURG, V27, P358, DOI 10.1097/00000637-199110000-00013
NR 20
TC 77
Z9 85
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-7043
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD MAR
PY 2001
VL 46
IS 3
BP 250
EP 254
DI 10.1097/00000637-200103000-00008
PG 5
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 411BL
UT WOS:000167478200014
PM 11293515
DA 2026-07-24
ER

PT J
AU Famiglietti, A
   Lazar, JF
   Henderson, H
   Hamm, M
   Malouf, S
   Margolis, M
   Watson, TJ
   Khaitan, PG
AF Famiglietti, Amber
   Lazar, John F.
   Henderson, Hayley
   Hamm, Margaret
   Malouf, Stefanie
   Margolis, Marc
   Watson, Thomas J.
   Khaitan, Puja Gaur
TI Management of anastomotic leaks after esophagectomy and gastric pull-up
SO JOURNAL OF THORACIC DISEASE
LA English
DT Review
DE Esophagectomy; anastomotic leak; endoluminal stent; endoluminal
   vacuum-assisted closure (EVAC); over-the-scope clips (OTSCs);
   endoluminal suturing
ID ENDOSCOPIC VACUUM THERAPY; UPPER GASTROINTESTINAL-TRACT; ASSISTED
   CLOSURE; IVOR-LEWIS; TREATMENT OPTIONS; METAL STENT; PERFORATIONS;
   DEFECTS; COMPLICATIONS; MULTICENTER
AB Anastomotic leak is one of the most feared complications of esophagectomy, leading to prolonged hospital stay, increased postoperative mortality, and additional cost both to the patient and the hospital. Historically, anastomotic leaks have been treated with several techniques including conservative measures, percutaneous or operative drainage, primary surgical repair with buttressing, T-tube drainage, or excision of the esophageal replacement conduit with end esophagostomy. With advances in treatment modalities, including endoscopic stenting, clips and suturing, endoluminal vacuum-assisted closure (EVAC), such leaks increasingly are being managed without operative re-intervention and with salvage of the esophageal replacement conduit. For the purposes of this review, we identified studies analyzing the management of postoperative leak after esophagectomy. We then compared the efficacy of the various newer modalities for closure of anastomotic leaks and gastric conduit defects. We found both esophageal stent and EVAC sponges arc effective treatments for closure of anastomotic leak. The chosen treatment modality for salvage of the esophageal replacement conduit is entirely dependent on the patient's clinical status and the surgeon's preference and experience. Emerging endoscopic and endoluminal therapies have increased the armamentarium of tools the esophageal surgeon has to facilitate successful resolution of anastomotic leaks following esophagectomy with reconstruction. While some literature suggests that EVACs have a slightly superior result in conduit success, we question this endorsement as EVACs mostly are utilized for contained leaks, many of which may have healed with conservative measures. This posses a challenge as there is dearly a bias given patient selection.
C1 [Famiglietti, Amber; Lazar, John F.; Henderson, Hayley; Hamm, Margaret; Malouf, Stefanie; Margolis, Marc; Watson, Thomas J.; Khaitan, Puja Gaur] Georgetown Univ, Sch Med, MedStar Washington Hosp Ctr, Dept Surg, Washington, DC USA.
   [Lazar, John F.; Henderson, Hayley; Hamm, Margaret; Malouf, Stefanie; Margolis, Marc; Watson, Thomas J.; Khaitan, Puja Gaur] Georgetown Univ, Sch Med, MedStar Washington Hosp Ctr, Div Thorac & Esophageal Surg, Washington, DC USA.
C3 Georgetown University; MedStar Washington Hospital Center; Georgetown
   University; MedStar Washington Hospital Center
RP Khaitan, PG (通讯作者)，Georgetown Univ, Sch Med, MedStar Washington Hosp Ctr, Div Thorac & Esophageal Surg,Dept Surg, 110 Irving St NW G253, Washington, DC 20010 USA.
EM Puja.G.Khaitan@medstar.net
RI Khaitan, Puja/AAQ-6413-2020
OI Khaitan, Puja/0000-0001-8654-062X
CR Berlth F, 2019, J GASTROINTEST SURG, V23, P67, DOI 10.1007/s11605-018-4000-x
   Bludau M, 2014, SURG ENDOSC, V28, P896, DOI 10.1007/s00464-013-3244-5
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Brown AM, 2018, SURG ENDOSC, V32, P204, DOI 10.1007/s00464-017-5660-4
   Cai JX, 2014, ENDOSCOPY, V46, pE623, DOI 10.1055/s-0034-1390782
   Cerná M, 2011, CARDIOVASC INTER RAD, V34, P1267, DOI 10.1007/s00270-010-0059-9
   D'Cunha J, 2011, SEMIN THORAC CARDIOV, V23, P163, DOI 10.1053/j.semtcvs.2011.08.003
   D'Cunha J, 2011, J THORAC CARDIOV SUR, V142, P39, DOI 10.1016/j.jtcvs.2011.04.027
   Fernandez-Esparrach G, 2010, SURG OBES RELAT DIS, V6, P282, DOI 10.1016/j.soard.2010.02.036
   Flanagan JC, 2016, RADIOGRAPHICS, V36, P107, DOI 10.1148/rg.2016150126
   Fumagalli U, 2019, WORLD J GASTROENTERO, V25, P356, DOI 10.3748/wjg.v25.i3.356
   Gaur P, 2015, ANN THORAC SURG, V99, P1430, DOI 10.1016/j.athoracsur.2014.01.089
   Gubler C, 2013, DIS ESOPHAGUS, V26, P598, DOI 10.1111/dote.12005
   Guo JT, 2014, WORLD J SURG ONCOL, V12, DOI 10.1186/1477-7819-12-402
   Haito-Chavez Y, 2014, GASTROINTEST ENDOSC, V80, P610, DOI 10.1016/j.gie.2014.03.049
   Hwang JJ, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000003416
   Kantsevoy SV, 2014, GASTROINTEST ENDOSC, V79, P503, DOI 10.1016/j.gie.2013.10.051
   Kassis ES, 2013, ANN THORAC SURG, V96, P1919, DOI 10.1016/j.athoracsur.2013.07.119
   Kobara H, 2019, J GASTROEN HEPATOL, V34, P22, DOI 10.1111/jgh.14402
   KONES O, 2018, JSLS-J SOC LAPAROEND, V22, DOI DOI 10.4293/JSLS.2018.00011
   Kuwabara S, 2018, LANGENBECK ARCH SURG, V403, P607, DOI 10.1007/s00423-018-1674-1
   Laukoetter MG, 2017, SURG ENDOSC, V31, P2687, DOI 10.1007/s00464-016-5265-3
   Lee DH, 2013, DIS ESOPHAGUS, V26, P609, DOI 10.1111/dote.12011
   Liang DH, 2017, J THORAC CARDIOV SUR, V154, P1145, DOI 10.1016/j.jtcvs.2017.03.051
   Liang DH, 2017, J CARDIOTHORAC SURG, V12, DOI 10.1186/s13019-017-0570-z
   Mennigen R, 2015, GASTROINTEST ENDOSC, V82, P397, DOI 10.1016/j.gie.2015.02.027
   Mennigen R, 2015, J GASTROINTEST SURG, V19, P1229, DOI 10.1007/s11605-015-2847-7
   Mennigen R, 2014, WORLD J GASTROENTERO, V20, P7767, DOI 10.3748/wjg.v20.i24.7767
   Messager M, 2017, EJSO-EUR J SURG ONC, V43, P258, DOI 10.1016/j.ejso.2016.06.394
   Min YW, 2019, BMC SURG, V19, DOI 10.1186/s12893-019-0497-5
   Mutignani M, 2015, ENDOSCOPY, V47, pE376, DOI 10.1055/s-0034-1392238
   Rausa E, 2018, DIS ESOPHAGUS, V31, DOI 10.1093/dote/doy060
   Raymond D, 2012, SURG CLIN N AM, V92, P1299, DOI 10.1016/j.suc.2012.07.007
   Robertson C, 2018, INT J COLORECTAL DIS, V33, P91, DOI 10.1007/s00384-017-2923-4
   Schröder W, 2019, ANN SURG, V270, P820, DOI 10.1097/SLA.0000000000003538
   Smallwood NR, 2016, SURG ENDOSC, V30, P2473, DOI 10.1007/s00464-015-4501-6
   Souche R, 2020, SURG ENDOSC, V34, P142, DOI 10.1007/s00464-019-06742-w
   Speer E, 2016, SURG ENDOSC, V30, P3297, DOI 10.1007/s00464-015-4661-4
   Thomas M, 2014, ANN THORAC SURG, V97, P1459, DOI 10.1016/j.athoracsur.2013.08.051
   van Boeckel PGA, 2011, ALIMENT PHARM THER, V33, P1292, DOI 10.1111/j.1365-2036.2011.04663.x
   Van Daele E, 2016, INTERACT CARDIOV TH, V22, P32, DOI 10.1093/icvts/ivv276
   van den Berg MW, 2016, DIS ESOPHAGUS, V29, P572, DOI 10.1111/dote.12363
   van Rossum PSN, 2017, DIS ESOPHAGUS, V30, DOI 10.1111/dote.12472
   Wada T, 2014, ANN THORAC SURG, V97, P1071, DOI 10.1016/j.athoracsur.2013.06.093
   Watkins JR, 2018, THORAC SURG CLIN, V28, P541, DOI 10.1016/j.thorsurg.2018.07.002
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Weidenhagen R, 2010, ANN THORAC SURG, V90, P1674, DOI 10.1016/j.athoracsur.2010.07.007
   Williams RN, 2011, J GASTROINTEST SURG, V15, P777, DOI 10.1007/s11605-011-1472-3
   Youn HC, 2016, ANN THORAC CARDIOVAS, V22, P363, DOI 10.5761/atcs.cr.15-00305
NR 49
TC 41
Z9 48
U1 0
U2 1
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2072-1439
EI 2077-6624
J9 J THORAC DIS
JI J. Thorac. Dis.
PD MAR
PY 2020
VL 12
IS 3
BP 1022
EP 1030
DI 10.21037/jtd.2020.01.15
PG 9
WC Respiratory System
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System
GA KX2UJ
UT WOS:000521736500100
PM 32274171
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Willms, A
   Güsgen, C
   Schaaf, S
   Bieler, D
   von Websky, M
   Schwab, R
AF Willms, A.
   Guesgen, C.
   Schaaf, S.
   Bieler, D.
   von Websky, M.
   Schwab, R.
TI Management of the open abdomen using vacuum-assisted wound closure and
   mesh-mediated fascial traction
SO LANGENBECKS ARCHIVES OF SURGERY
LA English
DT Article
DE Open abdomen; Peritonitis; Abdominal trauma; Vacuum therapy; Abdominal
   compartment syndrome
ID TEMPORARY ABDOMINAL CLOSURE; SMALL-BOWEL FISTULAS; DAMAGE-CONTROL;
   SURGICAL COMPLICATIONS; COMPARTMENT SYNDROME; NEGATIVE-PRESSURE;
   GENERAL-SURGERY; WALL DEFECTS; TRAUMA; CLASSIFICATION
AB The open abdomen has become an accepted treatment option of critically ill patients with severe intra-abdominal conditions. Fascial closure is a particular challenge in patients with peritonitis. This study investigates whether fascial closure rates can be increased in peritonitis patients by using an algorithm that combines vacuum-assisted wound closure and mesh-mediated fascial traction. Moreover, fascial closure rates for patients with peritonitis, trauma or abdominal compartment system (ACS) are compared.
   Data were collected prospectively from all patients who underwent open abdomen management at our institution from 2006 to 2012. All patients were treated under a standardised algorithm that combines vacuum-assisted closure and mesh placement at the fascial level.
   During the study period, 53 patients (mean age 53 years) underwent open abdomen management for a mean duration of 15 days. Indications for leaving the abdomen open were peritonitis (51 %), trauma (26 %), and ACS or abdominal wall dehiscence (23 %). The fascial closure rate was 79 % in an intention-to-treat analysis and 89 % in a per-protocol analysis. Mortality was 13 %. No patient developed an enteroatmospheric fistula or abdominal wall dehiscence after closure. The mean duration of treatment was significantly longer in peritonitis patients (20 days) than in patients without peritonitis (10 days) (p = 0.03). There were no significant differences in fascial closure rates between patients with peritonitis (87 %), trauma (85 %), and ACS or abdominal wall dehiscence (100 %) (p = 0.647).
   Regardless of the underlying pathology, high fascial closure rates can be achieved using a combination of vacuum-assisted closure and mesh-mediated fascial traction.
C1 [Willms, A.; Guesgen, C.; Schaaf, S.; Schwab, R.] German Armed Forces Cent Hosp Koblenz, Dept Gen Visceral & Thorac Surg, D-56072 Koblenz, Germany.
   [Willms, A.; von Websky, M.] Univ Hosp Bonn, Dept Gen Visceral Thorac & Vasc Surg, Bonn, Germany.
   [Bieler, D.] German Armed Forces Cent Hosp Koblenz, Dept Orthopaed Trauma Surg Reconstruct Surg Hand, D-56072 Koblenz, Germany.
C3 University of Bonn
RP Willms, A (通讯作者)，German Armed Forces Cent Hosp Koblenz, Dept Gen Visceral & Thorac Surg, Ruebenacher Str 170, D-56072 Koblenz, Germany.
EM ArnulfWillms@gmx.de
RI Bieler, Dan/HZL-5995-2023; Willms, Arnulf/AFN-0812-2022; von Websky,
   Martin/AFC-6767-2022
OI Bieler, Dan/0000-0002-0708-1259; Willms, Arnulf/0000-0001-9998-6735; 
CR Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
   Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Becker HP, 2007, SCAND J SURG, V96, P263, DOI 10.1177/145749690709600402
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   Bjorck M, 2012, Br J Surg, V99, P1732, DOI 10.1002/bjs.8917
   Bosscha K, 2000, EUR J SURG, V166, P44
   Burlew CC, 2012, AM J SURG, V204, P826, DOI 10.1016/j.amjsurg.2012.04.013
   Burlew CC, 2012, J TRAUMA ACUTE CARE, V72, P235, DOI 10.1097/TA.0b013e318236b319
   CLAVIEN PA, 1992, SURGERY, V111, P518
   Clavien PA, 2009, ANN SURG, V250, P187, DOI 10.1097/SLA.0b013e3181b13ca2
   De Potter TJR, 2005, INTENS CARE MED, V31, P747, DOI 10.1007/s00134-005-2597-1
   Demetriades D, 2014, SURG CLIN N AM, V94, P131, DOI 10.1016/j.suc.2013.10.010
   Diaz JJ, 2010, J TRAUMA, V68, P1425, DOI 10.1097/TA.0b013e3181da0da5
   Dietz UA, 2012, HERNIA, V16, P451, DOI 10.1007/s10029-012-0919-0
   Dindo D, 2004, ANN SURG, V240, P205, DOI [10.17116/hirurgia2018090162, 10.1097/01.sla.0000133083.54934.ae]
   DuBose JJ, 2013, J TRAUMA ACUTE CARE, V74, P113, DOI 10.1097/TA.0b013e31827891ce
   Ferguson Eric J, 2011, Am Surg, V77, pE74
   Garner GB, 2001, AM J SURG, V182, P630, DOI 10.1016/S0002-9610(01)00786-3
   Hatch QM, 2011, J TRAUMA, V71, P1503, DOI 10.1097/TA.0b013e31823cd78d
   Jannasch O, 2011, ZBL CHIR, V136, P575, DOI 10.1055/s-0031-1271347
   Joels CS, 2006, SURG INNOV, V13, P223, DOI 10.1177/1553350606296922
   Koss W, 2009, J SURG EDUC, V66, P89, DOI 10.1016/j.jsurg.2008.12.003
   López-Cano M, 2013, WORLD J GASTRO SURG, V5, P314, DOI 10.4240/wjgs.v5.i12.314
   Malbrain MLNG, 2006, INTENS CARE MED, V32, P1722, DOI 10.1007/s00134-006-0349-5
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   Nagy KK, 1996, AM SURGEON, V62, P331
   Oetting P, 2006, CHIRURG, V77, P586, DOI 10.1007/s00104-006-1200-9
   Padalino P, 2010, SURG INFECT, V11, P523, DOI 10.1089/sur.2010.042
   Pantelis D, 2012, CHIRURG, V83, P555, DOI 10.1007/s00104-011-2171-z
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   Petersson U, 2007, WORLD J SURG, V31, P2133, DOI 10.1007/s00268-007-9222-0
   Pliakos I, 2010, SURGERY, V148, P947, DOI 10.1016/j.surg.2010.01.021
   Quyn AJ, 2012, COLORECTAL DIS, V14, pE429, DOI 10.1111/j.1463-1318.2012.03045.x
   RAMIREZ OM, 1990, PLAST RECONSTR SURG, V86, P519, DOI 10.1097/00006534-199009000-00023
   Rasilainen SK, 2012, BRIT J SURG, V99, P1725, DOI 10.1002/bjs.8914
   Regner JL, 2012, WORLD J SURG, V36, P497, DOI 10.1007/s00268-011-1203-7
   Roberts DJ, 2012, J TRAUMA ACUTE CARE, V73, P629, DOI 10.1097/TA.0b013e31825c130e
   Salman AE, 2014, HERNIA, V18, P99, DOI 10.1007/s10029-012-1008-0
   Scott BG, 2005, SCAND J SURG, V94, P9, DOI 10.1177/145749690509400104
   Scott BG, 2006, J TRAUMA, V60, P17, DOI 10.1097/01.ta.0000200861.96568.bb
   Seternes A, 2010, EUR J VASC ENDOVASC, V40, P60, DOI 10.1016/j.ejvs.2010.02.018
   Smith BP, 2010, J GASTROINTEST LIVER, V19, P425
   Smith LA, 1997, AM SURGEON, V63, P1102
   Stevens P, 2009, INT WOUND J, V6, P259, DOI 10.1111/j.1742-481X.2009.00614.x
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Tsuei BJ, 2004, AM SURGEON, V70, P652
   Tukiainen E, 2011, BRIT J SURG, V98, P880, DOI 10.1002/bjs.7489
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   Vargo D, 2009, AM SURGEON, V75, pS1
   Verdam FJ, 2011, WORLD J SURG, V35, P2348, DOI 10.1007/s00268-011-1210-8
   Willms A, 2011, ZBL CHIR, V136, P592, DOI 10.1055/s-0031-1271440
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
NR 53
TC 57
Z9 66
U1 0
U2 10
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1435-2443
EI 1435-2451
J9 LANGENBECK ARCH SURG
JI Langenbecks Arch. Surg.
PD JAN
PY 2015
VL 400
IS 1
BP 91
EP 99
DI 10.1007/s00423-014-1240-4
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AY6WR
UT WOS:000347704100010
PM 25128414
DA 2026-07-24
ER

PT J
AU Brandi, C
   Grimaldi, L
   Nisi, G
   Silvestri, A
   Brafa, A
   Calabrò, M
   D'Aniello, C
AF Brandi, C.
   Grimaldi, L.
   Nisi, G.
   Silvestri, A.
   Brafa, A.
   Calabro, M.
   D'Aniello, C.
TI Treatment with vacuum-assisted closure and cryo-preserved homologous
   de-epidermalised dermis of complex traumas to the lower limbs with loss
   of substance, and bones and tendons exposure
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article
DE VAC therapy; Lower limbs injuries; DED; Traumatic wound
ID WOUND CONTROL; THERAPY; KERATINOCYTES; FIBROBLASTS; MANAGEMENT; CULTURE
AB Lower-limb injuries with toss of tissue and exposure of bones and tendons are an increasing problem. The condition of the wound locally and the patient in general does not always allow immediate and adequate coverage of the structures exposed by the trauma. Therefore, new therapeutic solutions are needed. A reduction in the time that bones and tendons are exposed is essential to achieve complete heating of bone fractures, with reduced risks of infection and less disabling outcomes.
   The effectiveness of vacuum-assisted closure (VAC) therapy in supporting wound heating and of cryopreserved homologous de-epidermalised dermis (DED) in providing an effective template for re-epithelialisation has been previously reported. We carried out a study to evaluate the effectiveness of the synergistic and combined use of the two methodologies. Eighteen patients with traumatic loss of tissue in the lower limbs, involving exposure of bone and tendon structures, were enrolled in the study. All participants had local, general contraindications to first-instance reconstructions, or both.
   All patients received a combination of VAC therapy and DED implants. Granulation tissue was obtained in all wounds, with complete coverage of exposed structures. No infections were detected in the cohort, and all patients were prepared for further necessary reconstructive treatments. In our experience, the combination of VAC therapy and DED could, in selected cases, constitute an effective treatment for complex lower limb traumatic injuries with bone and tendon exposure. (C) 2007 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Brandi, C.; Grimaldi, L.; Nisi, G.; Silvestri, A.; Brafa, A.; Calabro, M.; D'Aniello, C.] Univ Siena, Policlin S Maria Scotte, Dept Gen & Specialist Surg, Plast Surg Unit, I-53100 Siena, Italy.
C3 University of Siena
RP Brandi, C (通讯作者)，Univ Siena, Policlin S Maria Scotte, Dept Gen & Specialist Surg, Plast Surg Unit, Viale Bracci, I-53100 Siena, Italy.
EM cesarebrandi@virgilio.it
OI D'ANIELLO, CARLO/0000-0002-1561-9936; Nisi,
   Giuseppe/0000-0002-0357-8487; Grimaldi, Luca/0000-0002-9251-4396;
   BRANDI, CESARE/0000-0001-9755-7953
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Brandi Cesare, 2004, Chir Ital, V56, P425
   Clare MP, 2002, FOOT ANKLE INT, V23, P896, DOI 10.1177/107110070202301002
   Court-Brown CM, 1997, BRIT J PLAST SURG, V50, P570, DOI 10.1016/S0007-1226(97)90501-4
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   El Ghalbzouri A, 2002, CELL TISSUE RES, V310, P189, DOI 10.1007/s00441-002-0621-0
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Haddow DB, 2003, J BIOMED MATER RES A, V64A, P80, DOI 10.1002/jbm.a.10356
   Josty IC, 2001, BRIT J PLAST SURG, V54, P363, DOI 10.1054/bjps.2000.3565
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   Lee DY, 2005, ARCH DERMATOL RES, V296, P296, DOI 10.1007/s00403-004-0529-5
   Medalie DA, 1996, ASAIO J, V42, pM455, DOI 10.1097/00002480-199609000-00030
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mustoe T, 2004, AM J SURG, V187, p65S, DOI 10.1016/S0002-9610(03)00306-4
   NAVSARIA HA, 1993, BR J PLAST SURG, V46, P460
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Sposato G, 2001, BRIT J PLAST SURG, V54, P235, DOI 10.1054/bjps.2000.3537
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
NR 20
TC 10
Z9 23
U1 0
U2 3
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD DEC
PY 2008
VL 61
IS 12
BP 1507
EP 1511
DI 10.1016/j.bjps.2007.09.036
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 381EI
UT WOS:000261518000015
PM 17993300
DA 2026-07-24
ER

PT J
AU Arigon, JP
   Chapuis, O
   Sarrazin, E
   Pons, F
   Bouix, A
   Jancovici, R
AF Arigon, J. -P.
   Chapuis, O.
   Sarrazin, E.
   Pons, F.
   Bouix, A.
   Jancovici, R.
TI Managing the open abdomen with Vacuum-assisted closure therapy:
   retrospective evaluation of 22 patients
SO JOURNAL DE CHIRURGIE
LA French
DT Article
DE open abdomen; laparostomy; vacuum-assisted wound closure; abdominal
   compartment syndrome; sepsis; abdominal trauma
ID ABDOMINAL COMPARTMENT SYNDROME; PLANNED VENTRAL HERNIA; FASCIAL CLOSURE;
   WOUND CLOSURE; OPEN MANAGEMENT; WALL DEFECTS; TRAUMA; SEPSIS;
   PERITONITIS; STATE
AB Background: The authors reviewed their experience in the management of "open abdomen" using the vacuum-assisted closure device (VAC (R)), in order to assess its morbidity particularly in terms of fistula, and the outcome of abdominal wall integrity.
   Methods: Between January 2003 and October 2006, 22 patients required management with an "open abdomen" technique (18 patients were managed with the VAC, abdominal dressing device with application of a specific sheet and 4 other patients simply required a dressing with the polyurethane sponge). The mean age was 55 years, and M/F sex ratio was 2.67. Indications were abdominal compartment syndrome in 7 patients, initial "abdominal closure" after trauma in one patient, severe abdominal sepsis in 7 patients, and abdominal wound dehiscence where closure was impossible in 7 patients.
   Results: There were no enteric fistulae. Two infections were seen - a chronic suppuration which resolved with antibiotic therapy and a deep abscess which was drained with radiologic guidance. Of the 18 cases of "open abdomen" managed with the VAC, 15 were alive. Six (40%) underwent a delayed primary closure at a mean interval of 9 days; the others underwent secondary healing by granulation, and 10 eventually underwent split thickness skin grafting at a mean interval of 50 days. With VAC closure of the "open abdomen", the development of ventral hernia is an anticipated outcome; in four cases, patients underwent abdominal wall reconstruction at an interval of one year.
   Conclusion: Laparostomy or "open abdomen" using the VACO dressing system should be considered an established and well-defined technique which provides temporary abdominal coverage with limited morbidity.
C1 [Arigon, J. -P.; Chapuis, O.; Sarrazin, E.; Pons, F.; Bouix, A.; Jancovici, R.] Hop Instruct Armees Percy, Serv Chirurg Thorac & Viscerale, F-92140 Clamart, France.
RP Arigon, JP (通讯作者)，Hop Instruct Armees Percy, Serv Chirurg Thorac & Viscerale, F-92140 Clamart, France.
EM jp.arigon@gmail.com
CR Adkins AL, 2004, AM SURGEON, V70, P137
   Arvieux C, 2000, J CHIR-PARIS, V137, P133
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Bosscha K, 2000, EUR J SURG, V166, P44
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   Decker G, 2001, J CHIR-PARIS, V138, P270
   Durmishi Y, 2007, J CHIR-PARIS, V144, P209, DOI 10.1016/S0021-7697(07)89516-0
   FABIAN TC, 1994, ANN SURG, V219, P643, DOI 10.1097/00000658-199406000-00007
   Fernandez L, 1996, J TRAUMA, V40, P258, DOI 10.1097/00005373-199602000-00014
   Garner GB, 2001, AM J SURG, V182, P630, DOI 10.1016/S0002-9610(01)00786-3
   Heller L, 2006, AM J SURG, V191, P165, DOI 10.1016/j.amjsurg.2005.09.003
   Kaplan M., 2004, OSTOMY WOUND MANAG S, V50, P1
   Kaplan M, 2005, GUIDELINES MANAGEMEN
   Letoublon C, 2005, ANN CHIR, V130, P587, DOI 10.1016/j.anchir.2005.09.001
   Losanoff JE, 2002, J AM COLL SURGEONS, V195, P105, DOI 10.1016/S1072-7515(02)01149-3
   Meldrum DR, 1997, AM J SURG, V174, P667, DOI 10.1016/S0002-9610(97)00201-8
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Miller PR, 2002, J TRAUMA, V53, P843, DOI 10.1097/00005373-200211000-00007
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   PENNINCKX FM, 1983, WORLD J SURG, V7, P762, DOI 10.1007/BF01655218
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   RAMIREZ OM, 1990, PLAST RECONSTR SURG, V86, P519, DOI 10.1097/00006534-199009000-00023
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   SCHEIN M, 1986, SURG GYNECOL OBSTET, V163, P587
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Wittmann DH, 2000, J INTENSIVE CARE MED, V15, P201, DOI 10.1046/j.1525-1489.2000.00201.x
NR 28
TC 14
Z9 15
U1 0
U2 3
PU MASSON EDITEUR
PI MOULINEAUX CEDEX 9
PA 21 STREET CAMILLE DESMOULINS, ISSY, 92789 MOULINEAUX CEDEX 9, FRANCE
SN 0021-7697
J9 J CHIR-PARIS
JI J. Chir.
PD MAY-JUN
PY 2008
VL 145
IS 3
BP 252
EP 261
DI 10.1016/S0021-7697(08)73755-4
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 332NJ
UT WOS:000258089400010
PM 18772734
DA 2026-07-24
ER

PT J
AU Saxena, V
   Hwang, CW
   Huang, S
   Eichbaum, Q
   Ingber, D
   Orgill, DP
AF Saxena, V
   Hwang, CW
   Huang, S
   Eichbaum, Q
   Ingber, D
   Orgill, DP
TI Vacuum-assisted closure: Micro deformations of wounds and cell
   proliferation
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID ENDOTHELIAL-CELLS; SHEAR-STRESS; GROWTH; SHAPE; FIBRONECTIN; ACTIVATION;
   GRADIENTS; MODEL
AB The mechanism of action Of the Vacuum Assisted Closure Therapy (VAC; KCl, San Antonio, Texas), a recent novel innovation in the care of wounds, remains unknown. In vitro studies have revealed that cells allowed to stretch tend to divide and proliferate in the presence of soluble mitogens, whereas retracted cells remain quiescent. The authors hypothesize that application of micro-mechanical forces to wounds in vivo can promote wound healing through this cell shape-dependent, mechanical control mechanism. The authors created a computer model (finite element) of a wound and simulated VAC application. Finite element modeling is coin in only used to engineer complex systems by breaking them down into simple discrete elements. In this model, the authors altered the pressure, pore diameter, and pore volume fraction to study the effects of vacuum-induced material deformations. The authors compared the morphology of deformation of this wound model with histologic sections of wounds treated with the VAC The finite element model showed that most elements stretched by VAC application experienced deformations of 5 to 20 percent strain, which are similar to in vitro strain levels shown to promote cellular proliferation. Importantly, the deformation predicted by the model also was similar in morphology to the surface undulations observed in histologic cross-sections of the wounds. The authors hypothesize that this tissue deformation stretches individual cells, thereby promoting proliferation in the wound microenvironment. The application of micromechanical forces may be a useful method with which to stimulate wound healing through promotion of cell division, angiogenesis, and local elaboration of growth factors. Finite element modeling of the VAC device is consistent with this mechanism of action.
C1 Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Surg,Div Plast Surg, Boston, MA 02115 USA.
   Harvard Univ, Childrens Hosp, Sch Med, Dept Surg,Vasc Biol Program, Boston, MA 02115 USA.
   Harvard Univ, Childrens Hosp, Sch Med, Dept Pathol, Boston, MA 02115 USA.
   MIT, Dept Mech Engn, Cambridge, MA 02139 USA.
   MIT, Div Hlth Sci & Technol, Cambridge, MA 02139 USA.
   Harvard Univ, Massachusetts Gen Hosp, Sch Med, Cambridge, MA 02138 USA.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard Medical School; Harvard University; Harvard
   University Medical Affiliates; Boston Children's Hospital; Harvard
   Medical School; Harvard University; Harvard Medical School; Harvard
   University Medical Affiliates; Boston Children's Hospital; Massachusetts
   Institute of Technology (MIT); Massachusetts Institute of Technology
   (MIT); Harvard University; Harvard University Medical Affiliates;
   Massachusetts General Hospital
RP Saxena, V (通讯作者)，Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Surg,Div Plast Surg, 75 Francis St, Boston, MA 02115 USA.
RI Ingber, Donald/AAC-5894-2019; Orgill, Dennis/H-7596-2019
OI Orgill, Dennis/0000-0002-8279-7310
FU NCI NIH HHS [CA 45548] Funding Source: Medline
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong David G, 2002, Ostomy Wound Manage, V48, P64
   BJERRING P, 1985, ACTA DERM-VENEREOL, P83
   Chen CS, 1998, BIOTECHNOL PROGR, V14, P356, DOI 10.1021/bp980031m
   Chen CS, 1997, SCIENCE, V276, P1425, DOI 10.1126/science.276.5317.1425
   Clare MP, 2002, FOOT ANKLE INT, V23, P896, DOI 10.1177/107110070202301002
   FUNG YC, 1993, BIOMECHANICS MECH PR, P369
   Gimbrone MA Jr, 1997, J CLIN INVEST, V100, pS61
   Harrington C, 2000, DIABETES CARE, V23, P1333, DOI 10.2337/diacare.23.9.1333
   Huang S, 1999, NAT CELL BIOL, V1, pE131, DOI 10.1038/13043
   Huang S, 1998, MOL BIOL CELL, V9, P3179, DOI 10.1091/mbc.9.11.3179
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P249, DOI 10.1097/00003086-198901000-00038
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P263
   INGBER DE, 1990, P NATL ACAD SCI USA, V87, P3579, DOI 10.1073/pnas.87.9.3579
   Ingber DE, 1995, J BIOMECH, V28, P1471, DOI 10.1016/0021-9290(95)00095-X
   Korff T, 1999, J CELL SCI, V112, P3249
   MASANARI M, 2000, PLAST RECONSTR SURG, V106, P849
   McCallon S K, 2000, Ostomy Wound Manage, V46, P28
   MOCHITATE K, 1991, EXP CELL RES, V193, P198, DOI 10.1016/0014-4827(91)90556-A
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Nagel T, 1999, ARTERIOSCL THROM VAS, V19, P1825, DOI 10.1161/01.ATV.19.8.1825
   Orgill DP, 1998, J BURN CARE REHABIL, V19, P203, DOI 10.1097/00004630-199805000-00003
   Remmler D, 1998, PLAST RECONSTR SURG, V102, P1395, DOI 10.1097/00006534-199810000-00011
   Tardy Y, 1997, ARTERIOSCL THROM VAS, V17, P3102, DOI 10.1161/01.ATV.17.11.3102
   Webb Lawrence X, 2002, J Am Acad Orthop Surg, V10, P303
NR 25
TC 545
Z9 666
U1 0
U2 31
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD OCT
PY 2004
VL 114
IS 5
BP 1086
EP 1096
DI 10.1097/01.prs.0000135330.51408.97
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 861DQ
UT WOS:000224396700009
PM 15457017
DA 2026-07-24
ER

PT J
AU Fabian, TS
   Kaufman, HJ
   Lett, ED
   Thomas, JB
   Rawl, DK
   Lewis, PL
   Summitt, JB
   Merryman, JI
   Schaeffer, D
   Sargent, LA
   Burns, RP
AF Fabian, TS
   Kaufman, HJ
   Lett, ED
   Thomas, JB
   Rawl, DK
   Lewis, PL
   Summitt, JB
   Merryman, JI
   Schaeffer, D
   Sargent, LA
   Burns, RP
TI The evaluation of subatmospheric pressure and hyperbaric oxygen in
   ischemic full-thickness wound healing
SO AMERICAN SURGEON
LA English
DT Article; Proceedings Paper
CT 68th Annual Meeting of the Southeastern-Surgical-Congress
CY FEB 05-08, 2000
CL ORLANDO, FL
SP SE Surg Congress
ID VACUUM-ASSISTED CLOSURE; INSPIRED OXYGEN; ANGIOGENESIS; SURVIVAL;
   THERAPY; TENSION; STRESS; GROWTH; TRIAL
AB We evaluated the efficacy of subatmospheric pressure and hyperbaric oxygen (HBO) as adjuncts in the treatment of hypoxic full-thickness wounds in a rabbit model. We hypothesized that subatmospheric pressure and HBO independently are effective in improving wound healing in the ischemic wound model and that when they are used in combination there is an increased positive effect on wound healing. Using a standard ischemic wound model four full-thickness wounds were created on each ear of 41 male New Zealand white rabbits (N = 82 ears). On each rabbit one ear was dressed with the vacuum-assisted closure (VAC) device and connected to suction; the other was dressed identically without the suction and suction tubing. Twenty rabbits were treated with HBO daily for 10 days at 2.0 atmospheres absolute for 90 minutes plus descent and ascent times. Necropsy on all rabbits was performed on postoperative day 10. Four ischemic wound treatment groups were evaluated: Group 1 (N = 21) VAC dressing alone; Group 2 (N = 20) VAC dressing plus HBO; Group 3 (N = 21) VAC dressing to suction alone; and Group 4 (N = 20) VAC dressing to suction and HBO. Using light microscopy a veterinary pathologist blinded to treatment groups quantified peak granulation tissue, granulation tissue gap, and epithelialization tissue gap. Data were analyzed by analysis of variance with significance indicated by P < 0.05. Statistical significance was found in a comparison of VAC dressing to suction and VAC dressing alone for peak granulation tissue and granulation tissue gap both with and without use of HBO. VAC device use appears to increase the rate of healing in a rabbit ischemic wound model. HBO therapy did not significantly affect the rate of healing in this model.
C1 Univ Tennessee, Coll Med, Dept Surg, Chattanooga Unit, Chattanooga, TN 37403 USA.
   Univ Tennessee, Coll Med, Dept Plast Surg, Chattanooga Unit, Chattanooga, TN 37403 USA.
   Univ Tennessee, Coll Med, Knoxville, TN USA.
   Washington Univ, Sch Med, Div Plast & Reconstruct Surg, St Louis, MO USA.
C3 University of Tennessee System; University of Tennessee Health Science
   Center; University of Tennessee System; University of Tennessee Health
   Science Center; University of Tennessee System; University of Tennessee
   Health Science Center; Washington University (WUSTL)
RP Burns, RP (通讯作者)，Univ Tennessee, Coll Med, Dept Surg, Chattanooga Unit, 979 E 3rd St,Suite 401, Chattanooga, TN 37403 USA.
CR AHN ST, 1990, ANN PLAS SURG, V24, P17, DOI 10.1097/00000637-199001000-00004
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BEAMAN L, 1984, ANNU REV MICROBIOL, V38, P27
   BEHNKE AR, 1967, NEW ENGL J MED, V276, P1423, DOI 10.1056/NEJM196706222762507
   BIRD AD, 1966, SURG GYNECOL OBSTETR, V123, P260
   BIRD AD, 1965, LANCET, V1, P355
   Brannen AL, 1997, AM SURGEON, V63, P205
   CAFFEE HH, 1988, PLAST RECONSTR SURG, V81, P751, DOI 10.1097/00006534-198805000-00017
   CHERRY GW, 1983, PLAST RECONSTR SURG, V72, P680, DOI 10.1097/00006534-198311000-00018
   Clark R.A.F., 1988, MOL CELLULAR BIOL WO
   Cohen I.K., 1992, WOUND HEALING BIOCH
   GRUBER RP, 1970, ARCH SURG-CHICAGO, V101, P69
   HAMMARLUND C, 1994, PLAST RECONSTR SURG, V93, P829, DOI 10.1097/00006534-199404000-00026
   HENG MCY, 1993, J DERMATOL SURG ONC, V19, P784, DOI 10.1111/j.1524-4725.1993.tb00425.x
   HOHN DC, 1976, SURG FORUM, V27, P18
   HOHN DC, 1977, AM J SURG, V133, P597, DOI 10.1016/0002-9610(77)90018-6
   HUNT TK, 1988, ANN EMERG MED, V17, P1265, DOI 10.1016/j.mpsur.2017.06.004
   HUNT TK, 1972, SURG GYNECOL OBSTETR, V135, P561
   Hyperbaric Medical Solutions, Cardiology and Oxygen Therapy|Hyperbaric Medical Solutions
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P249, DOI 10.1097/00003086-198901000-00038
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P263
   JACOBSON JH, 1965, ANN NY ACAD SCI, V117, P651
   KERNAHAN D A, 1965, Plast Reconstr Surg, V36, P19, DOI 10.1097/00006534-196507000-00005
   KNIGHTON DR, 1984, ARCH SURG-CHICAGO, V119, P199
   KNIGHTON DR, 1981, SURGERY, V90, P262
   KULONEN E, 1968, ACTA PHYSIOL SCAND, V73, P383, DOI 10.1111/j.1748-1716.1968.tb04116.x
   MANSFIELD MJ, 1991, J ORAL USRG, V7, P47
   MARX RE, 1990, AM J SURG, V160, P519, DOI 10.1016/S0002-9610(05)81019-0
   MARX RE, 1985, J AM DENT ASSOC, V111, P49, DOI 10.14219/jada.archive.1985.0074
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   NIINIKOSKI J, 1972, AM J SURG, V123, P247, DOI 10.1016/0002-9610(72)90277-2
   OLENIUS M, 1993, PLAST RECONSTR SURG, V91, P213, DOI 10.1097/00006534-199302000-00001
   PACKER M, 1986, AM J CARDIOL, V57, P853, DOI 10.1016/0002-9149(86)90626-0
   QUIRINIA A, 1995, BRIT J PLAST SURG, V48, P583, DOI 10.1016/0007-1226(95)90049-7
   ROBSON MC, 1990, CLIN PLAST SURG, V17, P485
   Sheffield P., 1988, Problem Wounds: The Role of Oxygen, P17
   Sheffield P.J., 1985, Hyperb Oxyg Rev, V6, P18
   Shoshani O, 1998, BRIT J PLAST SURG, V51, P67, DOI 10.1054/bjps.1997.0060
   STARK GB, 1987, PLAST RECONSTR SURG, V80, P570, DOI 10.1097/00006534-198710000-00016
   SULLIVAN SM, 1981, AM J PHYSIOL, V241, pH542, DOI 10.1152/ajpheart.1981.241.4.H547
   Thoma R., 1911, VIRCHOWS ARCH PATHOL, V204, P1
   UHL E, 1994, PLAST RECONSTR SURG, V93, P835, DOI 10.1097/00006534-199404000-00028
   URSCHEL JD, 1988, BRIT J PLAST SURG, V41, P182, DOI 10.1016/0007-1226(88)90049-5
   Williams C T, 1885, Br Med J, V1, P824
   ZHAO LL, 1994, ARCH SURG-CHICAGO, V129, P1043
NR 45
TC 101
Z9 152
U1 0
U2 6
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0003-1348
EI 1555-9823
J9 AM SURGEON
JI Am. Surg.
PD DEC
PY 2000
VL 66
IS 12
BP 1136
EP 1143
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 383HE
UT WOS:000165876400016
PM 11149585
DA 2026-07-24
ER

PT J
AU Sziklavari, Z
   Grosser, C
   Neu, R
   Schemm, R
   Szöke, T
   Ried, M
   Hofmann, HS
AF Sziklavari, Zsolt
   Grosser, Christian
   Neu, Reiner
   Schemm, Rudolf
   Szoeke, Tamas
   Ried, Michael
   Hofmann, Hans-Stefan
TI Minimally invasive vacuum-assisted closure therapy in the management of
   complex pleural empyema
SO INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
LA English
DT Article
DE Empyema; Minimally invasive surgery; VAC therapy; Wound closure
ID OPEN-WINDOW THORACOSTOMY; INTRATHORACIC APPLICATION; DEVICE
AB OBJECTIVES: The pool of potential candidates for pleural empyema is expanding. In a previous technical report, we tested the feasibility of the minimally invasive insertion of a vacuum-assisted closure (Mini-VAC) system without the insertion of an open-window thoracostomy (OWT). In this study, we describe a consecutive case series of complex pleural empyemas that were managed by this Mini-VAC therapy.
   METHODS: In this retrospective study, we investigated 6 patients with multimorbidity (Karnofsky index <= 50%) who were consecutively treated with Mini-VAC for a primary, postoperative or recurrent pleural empyema between January 2011 and February 2012.
   RESULTS: Local control of the infection and control of sepsis were satisfactory in all 6 of the patients treated by Mini-VAC therapy. The suction used did not create any air leaks or bleeding from the lung or mediastinal structures. Mini-VAC therapy allowed a reduction of the empyema cavity and improved the re-expansion of the residual lung. Mini-VAC therapy resulted in a rapid eradication of the empyema. The chest wall was closed in all patients during the first hospital stay. All patients left the hospital in good health (Karnofsky index > 70%) and with a non-infected pleural cavity at a mean of 22 +/- 11 days after Mini-VAC installation. Pleural empyema was not detected in any of the 6 patients at the 3-month follow-up appointment.
   CONCLUSIONS: The Mini-VAC procedure with the abdication of an OWT offers a rapid treatment for complex pleural empyema with minimal surgical effort and the opportunity for a primary closure of the empyema cavity.
C1 [Sziklavari, Zsolt; Grosser, Christian; Schemm, Rudolf; Szoeke, Tamas; Hofmann, Hans-Stefan] Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, D-93049 Regensburg, Germany.
   [Neu, Reiner; Ried, Michael; Hofmann, Hans-Stefan] Univ Regensburg, Dept Thorac Surg, D-93053 Regensburg, Germany.
C3 University of Regensburg
RP Hofmann, HS (通讯作者)，Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, Prufeningerstr 86, D-93049 Regensburg, Germany.
EM hans-stefan.hofmann@barmherzige-regensburg.de
RI Sziklavari, Zsolt/AGI-2440-2022; Ried, Michael/AAC-4518-2022
OI Ried, Michael/0000-0002-2365-4803
CR Clagett O, 1963, J THORAC CARDIOVASC, V44, P141
   Eloesser L, 1935, SURG GYNECOL OBSTET, V60, P1096
   Groetzner J, 2009, THORAC CARDIOV SURG, V57, P417, DOI 10.1055/s-0029-1185907
   Haghshenasskashani A, 2011, INTERACT CARDIOV TH, V13, P168, DOI 10.1510/icvts.2011.267286
   Hofmann HS, 2012, ANN THORAC SURG, V93, P1741, DOI 10.1016/j.athoracsur.2011.12.039
   Kho P, 2011, INTERACT CARDIOV TH, V12, P724, DOI 10.1510/icvts.2010.247619
   Molnar TF, 2007, EUR J CARDIO-THORAC, V32, P422, DOI 10.1016/j.ejcts.2007.05.028
   Palmen M, 2009, ANN THORAC SURG, V88, P1131, DOI 10.1016/j.athoracsur.2009.06.030
   Saadi A, 2011, ANN THORAC SURG, V91, P1582, DOI 10.1016/j.athoracsur.2011.01.018
   SHAPIRO MP, 1988, AM J ROENTGENOL, V150, P549, DOI 10.2214/ajr.150.3.549
   Sziklavari Z, 2011, THORAC CARDIOV SURG, V6, P130
   Varker KA, 2006, ANN THORAC SURG, V81, P723, DOI 10.1016/j.athoracsur.2004.10.040
NR 12
TC 21
Z9 26
U1 0
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1569-9293
J9 INTERACT CARDIOV TH
JI Interact Cardiovasc. Thorac. Surg.
PD JUL
PY 2013
VL 17
IS 1
BP 49
EP 53
DI 10.1093/icvts/ivt093
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 170NI
UT WOS:000320858900012
PM 23536021
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU O'Connor, J
   Kells, A
   Henry, S
   Scalea, T
AF O'Connor, J
   Kells, A
   Henry, S
   Scalea, T
TI Vacuum-assisted closure for the treatment of complex chest wounds
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID INFECTIONS
AB Background. Destruction of chest wall musculature from trauma, empyema, or local infection limits closure options, especially with muscle flaps. While the vacuum-assisted closure system (VAC; KCI International, San Antonio, TX) has been used for wounds in other anatomic locations, we have found no series for chest wounds.
   Methods. This is a retrospective review of trauma registry data from the R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine from 2000 to 2003.
   Results. Seventeen patients were identified and divided into two groups. Group I consisted of seven patients with primary chest wall processes: four necrotizing soft-tissue infections and three with thoracic trauma resulting in significant loss of chest wall musculature. Group II consisted of ten patients with empyema and varying levels of chest wall extension. Six were postpneumonic and four postoperative. Wound size averaged 16 x 7 cm (range, 7 x 3 cm to 21 x 11 cm). The VAC duration averaged nine days (range, 3 to 21 days) and changed every two to three days. Fourteen wounds were culture positive; nine staphylococcus aureus, two alpha hemolytic streptococcus, and one each with enterococcus, Citrobacter, and anaerobes. Eight were polymicrobial. There were no deaths. All wounds healed without rotational muscle flaps. Ten underwent delayed primary closure, four split-thickness skin graft, and three healed by secondary intention. There was one significant complication: a wound infection after delayed primary closure which required reoperation.
   Conclusions. Closure of complex chest wall wounds can present significant technical challenges. The VAC system is a simple, useful, and novel alternative to conventional wound care even with large, infected wounds. (c) 2005 by The Society of Thoracic Surgeons.
C1 Univ Maryland, Sch Med, R Adams Cowley Shock Trauma Ctr, Dept Thorac & Vasc Surg, Baltimore, MD 21201 USA.
   Univ Maryland, Sch Med, R Adams Cowley Shock Trauma Ctr, Dept Surg & Crit Care, Baltimore, MD 21201 USA.
   Univ Maryland, Sch Med, R Adams Cowley Shock Trauma Ctr, Dept Wound Healing & Metab, Baltimore, MD 21201 USA.
   Univ Maryland, Sch Med, R Adams Cowley Shock Trauma Ctr, Program Trauma, Baltimore, MD 21201 USA.
C3 University System of Maryland; University of Maryland Baltimore;
   University System of Maryland; University of Maryland Baltimore;
   University System of Maryland; University of Maryland Baltimore;
   University System of Maryland; University of Maryland Baltimore
RP O'Connor, J (通讯作者)，Univ Maryland, Sch Med, R Adams Cowley Shock Trauma Ctr, Dept Thorac & Vasc Surg, 22 S Greene St, Baltimore, MD 21201 USA.
EM joconnor@umm.edu
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Arnold PG, 1996, PLAST RECONSTR SURG, V98, P804, DOI 10.1097/00006534-199610000-00008
   Brown KM, 2001, ANN THORAC SURG, V72, P1409, DOI 10.1016/S0003-4975(01)02844-2
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   Hersh RE, 2001, HEART SURG FORUM, V4, P211
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Urschel JD, 1997, ANN THORAC SURG, V64, P276, DOI 10.1016/S0003-4975(97)00514-6
NR 9
TC 48
Z9 74
U1 1
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD APR
PY 2005
VL 79
IS 4
BP 1196
EP 1200
DI 10.1016/j.athoracsur.2004.09.041
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 912PH
UT WOS:000228091100017
PM 15797049
OA Bronze
DA 2026-07-24
ER

PT J
AU Krasivskyi, I
   Ivanov, B
   Eghbalzadeh, K
   Fehlau, F
   Gerfer, S
   Grossmann, C
   Elderia, A
   Sabashnikov, A
   Rahmanian, PB
   Mader, N
   Djordjevic, I
   Wahlers, T
AF Krasivskyi, Ihor
   Ivanov, Borko
   Eghbalzadeh, Kaveh
   Fehlau, Frederike
   Gerfer, Stephen
   Grossmann, Clara
   Elderia, Ahmed
   Sabashnikov, Anton
   Rahmanian, Parwis Baradaran
   Mader, Navid
   Djordjevic, Ilija
   Wahlers, Thorsten
TI Sex-Associated Differences in Short-Term Outcomes in Patients with Deep
   Sternal Wound Infection after Open-Heart Surgery
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE deep sternal wound infection; cardiac surgery; sex; VAC therapy
ID BYPASS GRAFT-SURGERY; VACUUM-ASSISTED CLOSURE; RISK-FACTOR-ANALYSIS;
   GENDER-DIFFERENCES; CARDIAC-SURGERY; ARTERY; MEDIASTINITIS; MORTALITY;
   WOMEN; SURVIVAL
AB Deep sternal wound infection (DSWI) is a feared complication after cardiac surgery. The impact of sex-related differences on wound infection prevalence is poorly understood. Our aim was to evaluate the effect of sex on short-term outcomes in patients with DSWI after open-heart surgery. The study was a retrospective cohort study. A total of 217 patients with DSWI were identified and retrospectively analyzed using our institutional database. Patients were divided into two groups: males (n = 150) and females (n = 67). This study also includes a propensity score based matching (PSM) analysis (male group (n = 62) and female group (n = 62)) to examine the unequal groups. Mean age (p = 0.088) and mean body mass index (BMI) (p = 0.905) did not significantly differ between both groups. Vacuum assisted closure (VAC) therapy was performed among most patients (82.3% (male group) vs. 83.9% (female group), p = 0.432). The most commonly isolated bacteria from the wounds were Staphylococcus epidermidis and Staphylococcus aureus in both groups. Acute renal failure was significantly higher (p = 0.010) in the male group compared to the female group. However, dialysis rate did not significantly differ (p = 0.491) between male and female groups. Further secondary outcomes showed no major differences between the groups. Likewise, in-hospital mortality rate did not differ significantly (p = 0.680) between both groups. Based on our data, sex has no impact on deep wound infection prevalence after cardiac surgery.
C1 [Krasivskyi, Ihor; Eghbalzadeh, Kaveh; Fehlau, Frederike; Gerfer, Stephen; Grossmann, Clara; Elderia, Ahmed; Sabashnikov, Anton; Rahmanian, Parwis Baradaran; Mader, Navid; Djordjevic, Ilija; Wahlers, Thorsten] Univ Hosp Cologne, Dept Cardiothorac Surg, D-50937 Cologne, Germany.
   [Ivanov, Borko] Helios Hosp Siegburg, Dept Cardiothorac Surg, D-53721 Siegburg, Germany.
C3 University of Cologne
RP Krasivskyi, I (通讯作者)，Univ Hosp Cologne, Dept Cardiothorac Surg, D-50937 Cologne, Germany.
EM ihor.krasivskyi@uk-koeln.de
RI Sabashnikov, Anton/ABD-7044-2020; Gerfer, Stephen/ADX-0390-2022;
   Eghbalzadeh, Kaveh/PDX-7721-2025; Rahmanian, Parwis/E-5862-2010;
   Djordjevic, Ilija/AAN-3307-2020; Elderia, Ahmed/AEK-7200-2022
OI Krasivskyi, Ihor/0000-0003-0573-8218; Wahlers,
   Thorsten/0000-0002-8437-4119; Djordjevic, Ilija/0000-0002-5810-8626;
   Elderia, Ahmed/0000-0002-6859-5384
CR Abboud CS, 2004, ANN THORAC SURG, V77, P676, DOI 10.1016/S0003-4975(03)01523-6
   Abramov D, 2000, ANN THORAC SURG, V70, P800, DOI 10.1016/S0003-4975(00)01563-0
   Bitkover CY, 1998, ANN THORAC SURG, V65, P36, DOI 10.1016/S0003-4975(97)01003-5
   BOR DH, 1983, REV INFECT DIS, V5, P885
   Borger MA, 1998, ANN THORAC SURG, V65, P1050, DOI 10.1016/S0003-4975(98)00063-0
   BrandrupWognsen G, 1996, EUR HEART J, V17, P1426
   Bratzler DW, 2006, CLIN INFECT DIS, V43, P322, DOI 10.1086/505220
   Bryan CS, 2013, TEX HEART I J, V40, P125
   Chaker Z, 2017, J AM HEART ASSOC, V6, DOI 10.1161/JAHA.117.006370
   COPELAND M, 1994, ARCH SURG-CHICAGO, V129, P757
   Cotogni Paolo, 2015, World J Crit Care Med, V4, P265, DOI [10.5492/wjccm.v4.i4.265, 10.5492/wjccm.v4.i4.265]
   Edwards FH, 1998, ANN THORAC SURG, V66, P125, DOI 10.1016/S0003-4975(98)00358-0
   Enginoev S, 2022, BRAZ J CARDIOV SURG, V37, P13, DOI 10.21470/1678-9741-2020-0444
   Filsoufi F, 2009, J CARDIOTHOR VASC AN, V23, P488, DOI 10.1053/j.jvca.2009.02.007
   Furui M, 2022, INT HEART J, V63, P426, DOI 10.1536/ihj.21-464
   Gatti G, 2017, CARDIOVASC REVASCULA, V18, P40, DOI 10.1016/j.carrev.2016.08.001
   Gaudino M, 2018, J AM HEART ASSOC, V7, DOI 10.1161/JAHA.118.009934
   Gummert JF, 2002, THORAC CARDIOV SURG, V50, P87, DOI 10.1055/s-2002-26691
   Guru V, 2006, CIRCULATION, V113, P507, DOI 10.1161/CIRCULATIONAHA.105.576652
   Guru V, 2004, J THORAC CARDIOV SUR, V127, P1158, DOI 10.1016/j.jtcvs.2003.12.008
   Hammar N, 1997, J AM COLL CARDIOL, V29, P659, DOI 10.1016/S0735-1097(96)00531-1
   Humphries KH, 2017, FRONT NEUROENDOCRIN, V46, P46, DOI 10.1016/j.yfrne.2017.04.001
   Itagaki S, 2013, HEART, V99, P849, DOI 10.1136/heartjnl-2013-303672
   Kieser TM, 2014, J THORAC CARDIOV SUR, V148, P1887, DOI 10.1016/j.jtcvs.2014.02.022
   KOUCHOUKOS NT, 1990, ANN THORAC SURG, V49, P210, DOI 10.1016/0003-4975(90)90140-2
   Kubota H, 2013, J CARDIOTHORAC SURG, V8, DOI 10.1186/1749-8090-8-132
   Merz CNB, 2019, NAT REV NEPHROL, V15, P776, DOI 10.1038/s41581-019-0208-6
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   Neugarten J, 2002, J AM SOC NEPHROL, V13, P2807, DOI 10.1097/01.ASN.0000035846.89753.D4
   Oswald I, 2021, THORAC CARDIOV SURG, V69, P639, DOI 10.1055/s-0040-1713662
   Raza S, 2014, J THORAC CARDIOV SUR, V148, P1257, DOI 10.1016/j.jtcvs.2014.06.058
   Rubens FD, 2016, ANN THORAC SURG, V101, P1677, DOI 10.1016/j.athoracsur.2015.10.031
   Saxena A, 2012, EUR J CARDIO-THORAC, V41, P755, DOI 10.1093/ejcts/ezr039
   Seeburger J, 2013, THORAC CARDIOV SURG, V61, P42, DOI 10.1055/s-0032-1331583
   Selten K, 2021, ANN THORAC CARDIOVAS, V27, P25, DOI 10.5761/atcs.oa.19-00293
   SEYFER AE, 1988, SURGERY, V104, P899
   Silbiger S, 2008, GENDER MED, V5, pS3, DOI 10.1016/j.genm.2008.03.002
   Sjögren J, 2005, ANN THORAC SURG, V80, P1270, DOI 10.1016/j.athoracsur.2005.04.010
   Taggart DP, 2016, NEW ENGL J MED, V375, P2540, DOI 10.1056/NEJMoa1610021
   Toumpoulis IK, 2005, CHEST, V127, P464, DOI 10.1378/chest.127.2.464
   Toumpoulis IK, 2006, J THORAC CARDIOV SUR, V131, P343, DOI 10.1016/j.jtcvs.2005.08.056
   Urbanowicz T, 2021, J THORAC DIS, V13, P2867, DOI 10.21037/jtd-20-3356
   Vos RJ, 2018, J HOSP INFECT, V100, P411, DOI 10.1016/j.jhin.2018.05.026
   Vos RJ, 2012, INTERACT CARDIOV TH, V14, P17, DOI 10.1093/icvts/ivr049
NR 44
TC 4
Z9 7
U1 1
U2 1
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD DEC
PY 2022
VL 11
IS 24
AR 7510
DI 10.3390/jcm11247510
PG 10
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 7E6GE
UT WOS:000901263100001
PM 36556125
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Bollero, D
   Carnino, R
   Risso, D
   Gangemi, EN
   Stella, M
AF Bollero, Daniele
   Carnino, Riccardo
   Risso, Daniela
   Gangemi, Ezio N.
   Stella, Maurizio
TI Acute complex traumas of the lower limbs: a modern reconstructive
   approach with negative pressure therapy
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; CLINICAL-EXPERIENCE; WOUND CLOSURE; MANAGEMENT;
   FRACTURES; INJURIES
AB Acute traumas of the lower limbs cause complex functional damage for the association of skin loss with exposed tendons, bones, and/or vessels, requiring a multidisciplinary approach. Once bone fixation and vascular repair have been carried out, the surgical treatment for skin damage is usually based on early coverage with conventional or microsurgical flaps. Negative pressure therapy can play a primary role in the management of the elderly or intensive care patients, where wounds are secondary to life-threatening problems. A total of 35 patients with 37 acute traumatic wounds of the lower limbs were treated with vacuum-assisted closure (VAC((R))) therapy for an average of 22 days (range 3-46 days). The sponge was applied the day after bone fixation, vascular repair, and surgical debridement of nonviable tissues, so as to obtain a better control of bleeding. After VAC treatment, all patients quickly developed healthy granulation tissue and a significant reduction in both extent and depth of wounds. Split-thickness skin grafts were used to cover granulation tissue in most of the cases (66%-24 cases), and then local flaps (13%-five cases) or direct sutures (8%-three cases). The wounds healed spontaneously without surgical management in four patients. One patient died during the treatment period for concomitant diseases. No relevant complications directly related to VAC((R)) therapy were observed other than one case of severe pain in an amputated stump. The average follow-up duration was 265 days (range 33-874 days). No further tegumentary reconstruction was required. VAC((R)) therapy may represent a valid alternative to immediate reconstruction in selected cases of acute complex traumas of the lower limb and allows for a stable functional result, using a minimally invasive approach.
C1 CTO Hosp, Dept Plast & Reconstruct Surg, Burn Ctr, Traumatol Ctr, I-10126 Turin, Italy.
C3 A.O.U. Citta della Salute e della Scienza di Torino
RP Bollero, D (通讯作者)，CTO Hosp, Dept Plast & Reconstruct Surg, Burn Ctr, Traumatol Ctr, Via Zuretti 29, I-10126 Turin, Italy.
EM dbollero@hotmail.com
RI Stella, Maurizio/JGD-2010-2023; Gangemi, Ezio Nicola/M-8754-2019
OI Gangemi, Ezio Nicola/0000-0003-4381-7443; Carnino,
   Riccardo/0009-0005-2578-6999
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BISCHOFF M, 2003, EUR J PLAST SURG, V26, P186
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Fleischmann W, 1995, Eur J Orthop Surg Traumatol, V5, P37, DOI 10.1007/BF02716212
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Hertel R, 1999, ARCH ORTHOP TRAUM SU, V119, P7, DOI 10.1007/s004020050346
   KATSAMOURIS AN, 1995, EUR J VASC ENDOVASC, V9, P64, DOI 10.1016/S1078-5884(05)80227-8
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Stewart KJ, 2001, BRIT J PLAST SURG, V54, P652, DOI 10.1054/bjps.2001.3667
   TEOT L, 2002, CLIN RELEVANCE WOUND, P39
   Weitz-Marshall Amanda D, 2002, J Am Acad Orthop Surg, V10, P379
   Wu SH, 2000, EUR J PLAST SURG, V23, P174, DOI 10.1007/s002380050243
   Zalavras Charalampos G, 2003, J Am Acad Orthop Surg, V11, P212
NR 15
TC 39
Z9 43
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JUL-AUG
PY 2007
VL 15
IS 4
BP 589
EP 594
DI 10.1111/j.1524-475X.2007.00267.x
PG 6
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA 200HP
UT WOS:000248754800020
PM 17650104
DA 2026-07-24
ER

PT J
AU Yeung, E
   Kaster, M
   Scheese, D
   Mathews, T
   Prezkop, G
   Golden, D
   Granet, J
   Behm, R
AF Yeung, Enoch
   Kaster, Matthew
   Scheese, Daniel
   Mathews, Trey
   Prezkop, Gabrielle
   Golden, Daniel
   Granet, Jason
   Behm, Robert
TI Closing Contaminated Fascial Defects With Synthetic Mesh and a
   Vacuum-Assisted Closure Device
SO JOURNAL OF SURGICAL RESEARCH
LA English
DT Article
DE Synthetic mesh; VAC dressing; Open abdomen; Fistula
ID ABDOMINAL-WALL DEFECTS; NEGATIVE-PRESSURE; POLYPROPYLENE; REPAIR;
   HERNIA; MANAGEMENT; IMPACT
AB Background: The use of synthetic mesh is considered too high risk, and therefore, not an option when closing a contaminated abdominal fascial defect. This study evaluated the clinical outcomes when using synthetic mesh combined with vacuum-assisted closure (VAC) dressing to close these facial defects.
   Materials and methods: From 2010 to 2016, a retrospective review was performed, including 34 patients in a single rural trauma center who underwent a damage control laparotomy in the presence of a contaminated or infected field. Definitive abdominal closure with a bridging polypropylene mesh along with the application of a VAC dressing was done in all cases. Data collection included baseline demographics, operative indication, postoperative complications, mortality and length of follow up.
   Results: Median age of the patients was 67 y (IQR 40-87 y), with 22 (65%) being male at the time of operation. The median duration of clinical follow-up was 15.15 mo. The observed complications included three fistulas, two hernias, nine draining sinus tracts, and three mesh explanations with an overall complication rate of 41.1%. Although the absolute observed fistula rate was 8.8% (3 cases), the adjusted mesh-related fistulas formation rate after chart review was 0.0%. No mortalities were attributed directly to mesh-related complication.
   Conclusions: This study found no mesh-related fistulas when using a synthetic mesh along with a VAC dressing for abdominal closure in a contaminated field. These results may provide a platform for further study regarding the safety of this technique. (C) 2020 Elsevier Inc. All rights reserved.
C1 [Yeung, Enoch; Kaster, Matthew; Scheese, Daniel; Mathews, Trey; Prezkop, Gabrielle; Golden, Daniel; Granet, Jason; Behm, Robert] Guthrie Robert Packer Hosp, Sayre, PA USA.
RP Behm, R (通讯作者)，Guthrie Clin, 1 Guthrie Sq, Sayre, PA 18840 USA.
EM robert.behm@guthrie.org
RI Scheese, Daniel/JXX-3586-2024
OI Mathews, Trey/0000-0001-6948-8874
CR Bucalo Brian, 1993, Wound Repair and Regeneration, V1, P181, DOI 10.1046/j.1524-475X.1993.10308.x
   Chew DKW, 2000, SURGERY, V127, P352, DOI 10.1067/msy.2000.100886
   Cobb WS, 2018, PLAST RECONSTR S S1, V142
   Diaz JJ, 2011, J TRAUMA, V71, P502, DOI 10.1097/TA.0b013e318227220c
   Diaz JJ, 2010, J TRAUMA, V68, P1425, DOI 10.1097/TA.0b013e3181da0da5
   FANSLER RF, 1995, AM J SURG, V170, P15, DOI 10.1016/S0002-9610(99)80244-X
   Greca FH, 2008, HERNIA, V12, P45, DOI 10.1007/s10029-007-0276-6
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   Klinge U, 2002, J SURG RES, V103, P208, DOI 10.1006/jsre.2002.6358
   Klosterhalfen B, 2013, J BIOMED MATER RES B, V101, P1393, DOI 10.1002/jbm.b.32958
   Leber GE, 1998, ARCH SURG-CHICAGO, V133, P378, DOI 10.1001/archsurg.133.4.378
   McNeeley SG, 1998, AM J OBSTET GYNECOL, V179, P1434
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Padalino P, 2010, SURG INFECT, V11, P523, DOI 10.1089/sur.2010.042
   Regner JL, 2012, WORLD J SURG, V36, P497, DOI 10.1007/s00268-011-1203-7
   Rosen MJ, 2009, AM J SURG, V197, P353, DOI 10.1016/j.amjsurg.2008.11.003
   Sistla Sarath Chandra, 2008, Cases J, V1, P370, DOI 10.1186/1757-1626-1-370
   SMITH PC, 1992, J TRAUMA, V32, P16, DOI 10.1097/00005373-199201000-00004
   VOYLES CR, 1981, ANN SURG, V194, P219, DOI 10.1097/00000658-198108000-00017
   Zhu LM, 2015, WORLD J GASTRO SURG, V7, P226, DOI 10.4240/wjgs.v7.i10.226
NR 21
TC 3
Z9 3
U1 0
U2 1
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0022-4804
EI 1095-8673
J9 J SURG RES
JI J. Surg. Res.
PD MAR
PY 2021
VL 259
BP 313
EP 319
DI 10.1016/j.jss.2020.09.031
EA FEB 2021
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA QK3GA
UT WOS:000620267800039
PM 33127065
DA 2026-07-24
ER

PT J
AU Walma, MS
   Burbach, JPM
   Verheijen, PM
   Pronk, A
   van Grevenstein, WMU
AF Walma, M. S.
   Burbach, J. P. M.
   Verheijen, P. M.
   Pronk, A.
   van Grevenstein, W. M. U.
TI Vacuum-assisted closure therapy for infected perineal wounds after
   abdominoperineal resection. A retrospective cohort study
SO INTERNATIONAL JOURNAL OF SURGERY
LA English
DT Article
DE Rectal cancer; Abdominoperineal resection; Perineal wound infection; VAC
   therapy
ID TOTAL MESORECTAL EXCISION; PREOPERATIVE RADIOTHERAPY; RECTAL-CANCER;
   COMPLICATIONS; MULTICENTER; MANAGEMENT; MORBIDITY; COLLAGEN
AB Introduction: Perineal wound complications are a main problem after abdominoperineal resection (APR). There is little evidence concerning perineal wound management. This study describes and evaluates the role of vacuum-assisted closure (VAC) therapy in wound management strategies of perineal wound infections after APR.
   Methods: Patients undergoing APR for malignant disease between January 2007 and January 2013 were identified retrospectively. Data regarding occurrence and management of perineal wound complications were collected. Perineal wound infections were classified into minor or major complications and time to wound healing was measured. Time to wound healing was compared between patients receiving routine care or with additional VAC therapy.
   Results: Of 171 included patients, 76 (44.4%) had minor and 36 (21.1%) major perineal wound infections. Management of major infected perineal wounds consisted of drainage (n = 16), debridement (n = 4), drainage combined with debridement (n = 4), VAC therapy alone (n = 5), or VAC therapy combined with other treatments (n = 7). Median duration of perineal wound healing in major infected wounds was 141 days (range 17-739). Median time to wound healing was not different in patients treated with (172 days, range 23-368) or without VAC therapy (131 days, range 17-739).
   Discussion and conclusion: In this study, VAC therapy did not shorten time to wound healing. However, prospective studies are required to investigate the role of VAC therapy in management of infected perineal wounds after APR. Up to then, wound management will remain to be based on clinical perception and 'gut-feeling'. (c) 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.
C1 [Walma, M. S.; Burbach, J. P. M.; van Grevenstein, W. M. U.] Univ Med Ctr, Dept Surg, Heidelberglaan 100, NL-3584 CX Utrecht, Netherlands.
   [Verheijen, P. M.] Meander Med Ctr, Dept Surg, Maatweg 3, NL-3813 TZ Amersfoort, Netherlands.
   [Pronk, A.] Diakonessen Hosp, Dept Surg, Bosboomstr 1, NL-3582 KE Utrecht, Netherlands.
C3 Meander Medisch Centrum; Diakonessenhuis
RP Walma, MS (通讯作者)，Univ Med Ctr, Dept Surg, Postbus 85500, NL-3508 GA Utrecht, Netherlands.
EM m.s.walma@umcutrecht.com
OI Verheijen, Paul/0000-0003-2213-8310
CR ALTEMEIER WA, 1974, AM J SURG, V127, P215, DOI 10.1016/0002-9610(74)90160-3
   [Anonymous], 2014, DUTCH GUIDELINE COLO
   ANTHONY JP, 1990, ARCH SURG-CHICAGO, V125, P1371
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Bullard KM, 2005, DIS COLON RECTUM, V48, P438, DOI 10.1007/s10350-004-0827-1
   Chadi SA, 2014, DIS COLON RECTUM, V57, P999, DOI 10.1097/DCR.0000000000000161
   Chadwick MA, 2006, COLORECTAL DIS, V8, P756, DOI 10.1111/j.1463-1318.2006.01029.x
   CHARLSON M, 1994, J CLIN EPIDEMIOL, V47, P1245, DOI 10.1016/0895-4356(94)90129-5
   CHARLSON ME, 1987, J CHRON DIS, V40, P373, DOI 10.1016/0021-9681(87)90171-8
   Christian CK, 2005, DIS COLON RECTUM, V48, P43, DOI 10.1007/s10350-004-0855-x
   Collin Å, 2013, COLORECTAL DIS, V15, P341, DOI 10.1111/j.1463-1318.2012.03196.x
   Cresti S, 2008, WORLD J SURG ONCOL, V6, DOI 10.1186/1477-7819-6-136
   de Bruin AFJ, 2008, TECH COLOPROCTOL, V12, P303, DOI 10.1007/s10151-008-0440-8
   Dindo D., 2004, Ann Surg
   El-Gazzaz G, 2009, DIS COLON RECTUM, V52, P1962, DOI 10.1007/DCR.0b013e3181b71ef9
   Enker WE, 1997, ANN MED, V29, P127, DOI 10.3109/07853899709113698
   Enoch S, 2006, BMJ-BRIT MED J, V332, P900, DOI 10.1136/bmj.332.7546.900
   Fujino S, 2015, INT J SURG CASE REP, V11, P87, DOI 10.1016/j.ijscr.2015.04.031
   Gruessner U, 2001, AM J SURG, V182, P502, DOI 10.1016/S0002-9610(01)00762-0
   Hoare D, 2013, INT J SURG, V11, P395, DOI 10.1016/j.ijsu.2013.02.028
   Howell AM, 2013, INT J SURG, V11, P514, DOI 10.1016/j.ijsu.2013.05.004
   Kapiteijn E, 2001, NEW ENGL J MED, V345, P638, DOI 10.1056/NEJMoa010580
   LOESSIN SJ, 1995, DIS COLON RECTUM, V38, P940, DOI 10.1007/BF02049729
   Luna-Pérez P, 2001, REV INVEST CLIN, V53, P388
   Marshall MJ, 2012, COLORECTAL DIS, V14, P12, DOI 10.1111/codi.12044
   Monsen C, 2014, J VASC SURG, V59, P145, DOI 10.1016/j.jvs.2013.06.073
   Nagtegaal ID, 2005, J CLIN ONCOL, V23, P9257, DOI 10.1200/JCO.2005.02.9231
   Papaconstantinou HT, 2006, COLORECTAL DIS, V8, P124, DOI 10.1111/j.1463-1318.2005.00911.x
   Petkar KS, 2011, BURNS, V37, P925, DOI 10.1016/j.burns.2011.05.013
   PETRELLI NJ, 1993, AM SURGEON, V59, P400
   Quan HD, 2005, MED CARE, V43, P1130, DOI 10.1097/01.mlr.0000182534.19832.83
   Robson MC, 2001, CURR PROB SURG, V38, P65
   ROTHENBERGER DA, 1992, WORLD J SURG, V16, P478, DOI 10.1007/BF02104451
   Showalter SL, 2013, AM J SURG, V206, P80, DOI 10.1016/j.amjsurg.2012.10.036
   Singer AJ, 1999, NEW ENGL J MED, V341, P738, DOI 10.1056/NEJM199909023411006
   Torre LA, 2015, CA-CANCER J CLIN, V65, P87, DOI 10.3322/caac.21262
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Wiatrek Rebecca L, 2008, Clin Colon Rectal Surg, V21, P76, DOI 10.1055/s-2008-1055325
   Zhou ZY, 2015, INT J SURG, V17, P15, DOI 10.1016/j.ijsu.2015.03.008
   Zorcolo L, 2011, COLORECTAL DIS, V13, P1407, DOI 10.1111/j.1463-1318.2010.02536.x
NR 40
TC 9
Z9 12
U1 0
U2 1
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 1743-9191
EI 1743-9159
J9 INT J SURG
JI Int. J. Surg.
PD FEB
PY 2016
VL 26
BP 18
EP 24
DI 10.1016/j.ijsu.2015.12.009
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA DE1GU
UT WOS:000370375900004
PM 26718610
DA 2026-07-24
ER

PT J
AU Salman, AE
   Yetisir, F
   Aksoy, M
   Tokaç, M
   Yildirim, MB
   Kiliç, M
AF Salman, A. E.
   Yetisir, F.
   Aksoy, M.
   Tokac, M.
   Yildirim, M. B.
   Kilic, M.
TI Use of dynamic wound closure system in conjunction with vacuum-assisted
   closure therapy in delayed closure of open abdomen
SO HERNIA
LA English
DT Article
DE Severe sepsis; Fascia; Abdomen
ID FASCIAL CLOSURE; MANAGEMENT
AB Definitive abdominal closure may not be possible for several days or weeks after laparotomy in damage-control surgery, abdominal compartment syndrome and intraabdominal sepsis, until the patient has stabilized. Vacuum-assisted closure (VAC therapy(A (R)), KCI, San Antonio, TX, USA) and abdominal re-approximation anchor system (ABRA, Canica, Almonte, Ontario, Canada) are novel techniques in delayed closure of open abdomen. Our aim is to present the use of these strategies in the management of 7 patients with open abdomen.
   Between August 2010 and December 2011, 7 patients with severe peritonitis were stabilized by laparotomy and treated with either ABRA system or ABRA system in conjunction with VAC dressing. VAC dressing applied to 4 patients initially and followed by ABRA. ABRA was applied alone to remaining 3 patients. Demographic data and patient characteristics, timing of VAC dressing and ABRA system were recorded. ICU and hospital stay and development of incisional hernia were also recorded. Stage of open abdomen, width of abdominal defect, extent to damage to fascia, and pressure sores were staged.
   The mean duration with VAC dressing before ABRA application was 18 days. The mean duration of ABRA application was 53 days. The average width of the abdominal defect was 18 cm. The average length of defect was 20.8 cm. Delayed primary abdominal closure was accomplished in 6 patients without further surgery. Incisional hernia with a small abdominal defect developed in 2 patients.
   Abdominal re-approximation anchor system and VAC dressing can be used separately or in conjunction with each other for closure of delayed open abdomen successfully.
C1 [Salman, A. E.] Etlik Res & Training Hosp, Dept Anesthesiol & Reanimat, Ankara, Turkey.
   [Yetisir, F.; Tokac, M.; Yildirim, M. B.; Kilic, M.] Etlik Res & Training Hosp, Dept Gen Surg, Ankara, Turkey.
   [Aksoy, M.] Ataturk Training & Res Hosp, Dept Anesthesiol & Reanimat, Ankara, Turkey.
C3 Ankara Etlik Ihtisas Egitim ve Arastirma Hastanesi; Ankara Etlik Ihtisas
   Egitim ve Arastirma Hastanesi; Ankara Etlik Ihtisas Egitim ve Arastirma
   Hastanesi
RP Salman, AE (通讯作者)，Etlik Res & Training Hosp, Dept Anesthesiol & Reanimat, Ankara, Turkey.
EM ebru.salman@gmail.com; drfahriyetisir@hotmail.com
RI ; TOKAÇ, MEHMET/AAA-9577-2021; AKSOY, SEI MUSTAFA/AAM-9773-2020;
   YILDIRIM, Murat Baki/AAP-6226-2021
OI yetisir, fahri/0000-0002-8216-1355; TOKAÇ, MEHMET/0000-0002-7278-0937;
   AKSOY, SEI MUSTAFA/0000-0003-3197-5655; YILDIRIM, Murat
   Baki/0000-0001-9176-1160
CR Barczak C A, 1997, Adv Wound Care, V10, P18
   Björck M, 2011, AM SURGEON, V77, pS58
   Björck M, 2009, WORLD J SURG, V33, P1154, DOI 10.1007/s00268-009-9996-3
   Cano-Lopez M, 2011, USE VACUUM ASSISTED
   Dal A, 2006, CAN J PLAST SURG, V14, P233
   Jacobs S, 2009, J PLAST RECONSTR AES, V62, P1331, DOI 10.1016/j.bjps.2008.03.024
   Mentula P, 2011, MINERVA CHIR, V66, P153
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Regner JL, 2012, WORLD J SURG, V36, P497, DOI 10.1007/s00268-011-1203-7
   Reimer MW, 2008, CAN J SURG, V51, P209
   Sziklavari Z, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-130
   Ulusal AE, 2011, ACTA ORTHOP TRAUMATO, V45, P254, DOI 10.3944/AOTT.2011.2283
   Urbaniak RM, 2006, ANN PLAS SURG, V57, P573, DOI 10.1097/01.sap.0000237052.11796.63
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Verdam FJ, 2011, WORLD J SURG, V35, P2348, DOI 10.1007/s00268-011-1210-8
NR 16
TC 37
Z9 42
U1 0
U2 9
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1265-4906
EI 1248-9204
J9 HERNIA
JI Hernia
PD FEB
PY 2014
VL 18
IS 1
BP 99
EP 104
DI 10.1007/s10029-012-1008-0
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 304BK
UT WOS:000330720000012
PM 23108788
DA 2026-07-24
ER

PT J
AU Tavusbay, C
   Kar, H
   Cin, N
   Kamer, E
   Aksut, H
   Karahalli, O
   Atahan, K
   Haciyanli, M
AF Tavusbay, Cengiz
   Kar, Haldun
   Cin, Necat
   Kamer, Erdinc
   Aksut, Hayri
   Karahalli, Onder
   Atahan, Kemal
   Haciyanli, Mehmet
TI The use of vacuum-assisted wound closure system for management of
   difficult wounds.
SO BIOMEDICAL RESEARCH-INDIA
LA English
DT Article
DE Fournier's gangrene; Open abdomen; wound dehiscence; Vacuum assisted
   closure therapy
ID ABDOMINAL WOUNDS; SUBATMOSPHERIC PRESSURE; CLINICAL-EXPERIENCE; THERAPY;
   FISTULAS; STATE
AB We aimed to present the results of our different clinical practise experience about the treatment and management of extremely difficult wounds using the vacuum-assisted closure system (VAC). In this retrospective study, we analysed the records of 51 consecutive patients who were applied VAC for different clinical practise between 2008 and 2012 at the Izmir Katip Celebi University, Ataturk Education and Training Hospital. There were 51 patients in our study with an average age of 54.6(16-78) years and 22(43.1%) were male, and 29(56.9%) were females. We used VAC system to manage the wound in 29(56.9%) patients with wound dehiscence (with or without fascial necrosis), in 17(33.3%) patients with open abdomen, and in 5(9.8%) patients with Fournier gangrene. The average hospital stay was38.4 days (10-101). The average duration of VAC application was 24.3 (8-56) days. The average number the application of VAC dressingswas 12.01 (3 to 28). Directly VAC related complications (enteroatmospheric fistula and wound haematoma) were seen in two patients (3.9%). A total of 27(52.9%) patients underwent delayed primary or graft closure. In the remaining 19(37.2%) patients, the wound was left to granulate and heal by secondary intention. 5 (9.8%) patients died because of complications related to primary disease while on VAC application. We concluded that VAC is an important tool in the armamentarium of the surgeons managing in patients with complex and difficult wounds, particularly, in cases of open abdomen.
C1 [Tavusbay, Cengiz; Kar, Haldun; Cin, Necat; Kamer, Erdinc; Aksut, Hayri; Karahalli, Onder; Atahan, Kemal; Haciyanli, Mehmet] Izmir Katip Celebi Univ, Ataturk Res & Training Hosp, TR-35360 Izmir, Turkey.
C3 Izmir Katip Celebi University; Izmir Ataturk Training & Research
   Hospital
RP Tavusbay, C (通讯作者)，Erzene Mah Sehit Taha Carim Cad Ozveri Sitesi 3-1, TR-35050 Izmir, Turkey.
RI TAVUSBAY, Cengiz/N-9236-2014; kar, haldun/R-6845-2019; HACIYANLI,
   MEHMET/P-6709-2019; Kamer, Erdinc/A-5245-2009
OI Kamer, Erdinc/0000-0002-5084-5867
CR [Anonymous], EUR J TRAUMA
   Antony S, 2004, J NATL MED ASSOC, V96, P1073
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   BanwellP E., 2004, INT WOUND J, V1, P95
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   DeFranzo AJ, 1999, PLAST RECONSTR SURG, V104, P2145, DOI 10.1097/00006534-199912000-00031
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   Kamolz LP, 2004, BURNS, V30, P253, DOI 10.1016/j.burns.2003.12.003
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   Marinis A, 2009, SURG INFECT, V10, P47, DOI 10.1089/sur.2008.044
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Rao M, 2007, COLORECTAL DIS, V9, P266, DOI 10.1111/j.1463-1318.2006.01154.x
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Scheufler O, 2000, EUR J PLAST SURG, V23, P386, DOI 10.1007/s002380000189
   Starr-Marshall K, 2007, COLORECTAL DIS, V9, P573, DOI 10.1111/j.1463-1318.2007.01310.x
   Subramonia S, 2009, WORLD J SURG, V33, P931, DOI 10.1007/s00268-009-9947-z
   Teixeira PGR, 2008, AM SURGEON, V74, P891
   Webb Lawrence X, 2002, J Am Acad Orthop Surg, V10, P303
   Willy C, 2007, EUR J TRAUMA EMERG S, V33, P33, DOI 10.1007/s00068-007-6143-4
NR 22
TC 1
Z9 2
U1 0
U2 1
PU SCIENTIFIC PUBLISHERS INDIA
PI ALIGARH
PA 87-GREATER AZAD ENCLAVE, P O QUARSI, ALIGARH, 00000, INDIA
SN 0970-938X
J9 BIOMED RES-INDIA
JI Biomed. Res.-India
PD JUL-SEP
PY 2013
VL 24
IS 3
BP 329
EP 336
PG 8
WC Engineering, Biomedical; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Research & Experimental Medicine
GA 189ZZ
UT WOS:000322308100008
DA 2026-07-24
ER

PT J
AU Herr, M
   Grabein, B
   Palm, HG
   Efinger, K
   Riesner, HJ
   Friemert, B
   Willy, C
AF Herr, M.
   Grabein, B.
   Palm, H. -G.
   Efinger, K.
   Riesner, H. -J.
   Friemert, B.
   Willy, C.
TI Necrotizing fasciitis
SO UNFALLCHIRURG
LA German
DT Article
DE Necrotizing fasciitis; Necrotizing soft tissue infection; Streptococcus;
   Vacuum-assisted closure; Wound care
ID SOFT-TISSUE INFECTIONS; STREPTOCOCCUS-PYOGENES DISEASE; LABORATORY RISK
   INDICATOR; GROUP-A STREPTOCOCCUS; GANGRENE; EUROPE; SCORE
AB Necrotizing fasciitis belongs to a group of complicated soft tissue infections that can be even life threatening. Despite growing knowledge about its etiology, predictors, and the clinical progression, the mortality remains at a high level with 20%. A relevant reduction can be achieved only by an early diagnosis followed by consistent therapy. The clinical findings in about 75% of the cases are pain out of proportion, edema and tenderness, blisters, and erythema. It is elementary to differentiate a necrotizing or a non-necrotizing soft tissue infection early. In uncertain cases it can be necessary to perform a surgical exploration to confirm the diagnosis. The histopathologic characteristics are the fascial necrosis, vasculitis, thrombosis of perforating veins, the presence of the disease-causing bacteria as well as inflammatory cells like macrophages and polymorphonuclear granulocytes. Secondly, both the cutis and the muscle can be affected. In many cases there is a disproportion of the degree of local and systemic symptoms. Depending on the infectious agents there are two main types: type I is a polymicrobial infection and type II is a more invasive, serious, and fulminant monomicrobial infection mostly caused by group A Streptococcus pyogenes.
   Invasive, severe forms of streptococcal infections seem to occur more often in recent years. Multimodal and interdisciplinary therapy should be based on radical surgical d,bridement, systemic antibiotic therapy as well as enhanced intensive care therapy, which is sometimes combined with immunoglobulins (in streptococcal or staphylococcal infections) or hyperbaric oxygen therapy (HBOT, in clostridial infections). For wound care of extensive soft tissue defects vacuum-assisted closure has shown its benefit.
C1 [Willy, C.] Bundeswehrkrankenhaus Ulm, Chirurg Zentrum, D-89081 Ulm, Germany.
   [Herr, M.; Riesner, H. -J.; Friemert, B.] Bundeswehrkrankenhaus Ulm, Klin Unfallchirurg & Orthopadie, D-89081 Ulm, Germany.
   [Grabein, B.] Klinikum Univ Munchen, Klin Mikrobiol & Krankenhaushyg KMH, Munich, Germany.
   [Efinger, K.] Bundeswehrkrankenhaus Ulm, Abt Radiol Diagnost, D-89081 Ulm, Germany.
C3 Ulm University; Military Hospital Ulm; Ulm University; Military Hospital
   Ulm; University of Munich; Ulm University; Military Hospital Ulm
RP Willy, C (通讯作者)，Bundeswehrkrankenhaus Ulm, Chirurg Zentrum, Oberer Eselsberg 40, D-89081 Ulm, Germany.
EM ChristianWilly@Bundeswehr.org
RI /AAJ-3174-2021
CR Baer W, 2002, ORTHOPADE, V31, P551, DOI 10.1007/s00132-002-0306-0
   Brun-Buisson C, 2001, ANN DERMATOL VENER, V128, P394
   DESCAMPS V, 1994, LANCET, V344, P556, DOI 10.1016/S0140-6736(94)91956-9
   Elliott D, 2000, AM J SURG, V179, P361, DOI 10.1016/S0002-9610(00)00360-3
   Haywood CT, 1999, PLAST RECONSTR SURG, V103, P1567, DOI 10.1097/00006534-199905060-00003
   HOWARD RJ, 1985, SURGERY, V98, P126
   Johansson L, 2010, CLIN INFECT DIS, V51, P58, DOI 10.1086/653116
   Jones J, 1871, SURG MEMORIES WAR RE
   Karl T, 2005, VAKUUMTHERAPIE GRUND
   KLONTZ KC, 1988, ANN INTERN MED, V109, P318, DOI 10.7326/0003-4819-109-4-318
   Lacy MD, 2009, CLIN INFECT DIS, V49, P354, DOI 10.1086/599832
   Lamagni TL, 2008, J CLIN MICROBIOL, V46, P2359, DOI 10.1128/JCM.00422-08
   Lamothe F, 1995, CLIN INFECT DIS, V21, P1469, DOI 10.1093/clinids/21.6.1469
   Levenson RB, 2008, RADIOGRAPHICS, V28, P519, DOI 10.1148/rg.282075048
   Luca-Harari B, 2009, J CLIN MICROBIOL, V47, P1155, DOI 10.1128/JCM.02155-08
   Miller LG, 2005, NEW ENGL J MED, V352, P1445, DOI 10.1056/NEJMoa042683
   Nuwayhid ZB, 2007, ANN EPIDEMIOL, V17, P878, DOI 10.1016/j.annepidem.2007.05.011
   Puvanendran R, 2009, CAN FAM PHYSICIAN, V55, P981
   Ryssel H, 2010, ARCH ORTHOP TRAUM SU, V130, P1515, DOI 10.1007/s00402-010-1101-8
   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
   Sarkar B, 2010, MINERVA CHIR, V65, P347
   Schulze M, 2008, ROFO-FORTSCHR RONTG, V180, P587, DOI 10.1055/s-2008-1081063
   Silberstein J, 2008, NEW PARADIGM REV URO, V10, P76
   Su YC, 2008, ANZ J SURG, V78, P968, DOI 10.1111/j.1445-2197.2008.04713.x
   Wall DB, 2000, AM J SURG, V179, P17, DOI 10.1016/S0002-9610(99)00259-7
   Wong CH, 2004, CRIT CARE MED, V32, P1535, DOI 10.1097/01.CCM.0000129486.35458.7D
   Wong Chin-Ho, 2008, Am J Surg, V196, pe19, DOI 10.1016/j.amjsurg.2007.08.076
   Wysoki MG, 1997, RADIOLOGY, V203, P859, DOI 10.1148/radiology.203.3.9169717
   Yende Sachin, 2007, Curr Infect Dis Rep, V9, P382, DOI 10.1007/s11908-007-0059-3
   Yoneda A, 2010, INT SURG, V95, P76
   Zimbelman J, 1999, PEDIATR INFECT DIS J, V18, P1096, DOI 10.1097/00006454-199912000-00014
NR 31
TC 29
Z9 33
U1 0
U2 6
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0177-5537
EI 1433-044X
J9 UNFALLCHIRURG
JI Unfallchirurg
PD MAR
PY 2011
VL 114
IS 3
BP 197
EP +
DI 10.1007/s00113-010-1893-6
PG 18
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA 737ET
UT WOS:000288552600006
PM 21373930
DA 2026-07-24
ER

PT J
AU Pliakos, I
   Papavramidis, TS
   Mihalopoulos, N
   Koulouris, H
   Kesisoglou, I
   Sapalidis, K
   Deligiannidis, N
   Papavramidis, S
AF Pliakos, Ioannis
   Papavramidis, Theodossis S.
   Mihalopoulos, Nikolaos
   Koulouris, Harilaos
   Kesisoglou, Isaak
   Sapalidis, Konstantinos
   Deligiannidis, Nikolaos
   Papavramidis, Spiros
TI Vacuum-assisted closure in severe abdominal sepsis with or without
   retention sutured sequential fascial closure: A clinical trial
SO SURGERY
LA English
DT Article
ID TOPICAL NEGATIVE-PRESSURE; OPEN ABDOMEN; INTRAABDOMINAL HYPERTENSION;
   INTERNATIONAL-CONFERENCE; COMPARTMENT SYNDROME; WOUND CLOSURE; WALL
   RECONSTRUCTION; TEMPORARY CLOSURE; VENTRAL HERNIA; MANAGEMENT
AB Background. Multiple techniques have been introduced to obtain fascial closure for the open abdomen to minimize morbidity and cost of care. We hypothesized that a modification of the vacuum-assisted closure (VAC) technique that provides constant fascial tension and prevents abdominis rectis retraction would facilitate primary fascial closure and reduce morbidity.
   Methods. In all, 53 patients with severe abdominal sepsis were allocated randomly into 2 groups, and 30 patients were analyzed. In the VAC group, we included patients managed only with the VAC device, whereas the retentions sutured sequential fascial closure (RSSFC) group included patients to whom RSSFC was performed.
   Results. The abdomen was left open for 12 days (P = .0001) with 4.4 +/- 1.35 changes per patient for the VAC group (P = .001) and 8 days with 2.87 +/- 0.74 dressing changes per patient for the RSSFC group, respectively. Abdominal closure was possible in only 6 patients in the VAC group, whereas for the RSSFC group, abdominal closure was achieved in 14 patients (P = .005). Planned hernia was exclusively decided in patients in the VAC group (P = .001). The hospital stay was 17.53 +/- 4.59 days for the VAC group and 11.93 +/- 2.05 days for the RSSFC group (P = .0001). The median initial intra-abdominal pressure (IAP) was 12 mm Hg for the VAC group and 16 mm Hg for the RSSFC group (P < .0001).
   Conclusion. We demonstrated the superiority of RSSFC compared with the single use of the VAC device. In our opinion, sequential fascial closure can immediately begin when abdominal sepsis is controlled. (Surgery 2010;148:947-53.)
C1 [Pliakos, Ioannis; Papavramidis, Theodossis S.; Mihalopoulos, Nikolaos; Koulouris, Harilaos; Kesisoglou, Isaak; Sapalidis, Konstantinos; Deligiannidis, Nikolaos; Papavramidis, Spiros] Aristotle Univ Thessaloniki, Dept Surg 3, AHEPA Univ Hosp, Thessaloniki 56334, Greece.
C3 Aristotle University of Thessaloniki; Ahepa University Hospital
RP Pliakos, I (通讯作者)，Aristotle Univ Thessaloniki, Dept Surg 3, AHEPA Univ Hosp, M Sotyros 25, Thessaloniki 56334, Greece.
EM plliakos@hotmail.com
RI Sapalidis, Konstantinos/AAV-2866-2021; Papavramidis,
   Theodossis/E-8260-2011; Papavramidis, Theodossis/E-8260-2011;
   Michalopoulos, Nickos/I-6159-2013
OI Papavramidis, Theodossis/0000-0002-7097-9889; Papavramidis,
   Theodossis/0000-0002-7097-9889; Michalopoulos,
   Nickos/0000-0002-7740-4922
CR Albuquerque MLC, 2000, AM J PHYSIOL-HEART C, V279, pH293, DOI 10.1152/ajpheart.2000.279.1.H293
   Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   Breburda E, 2001, ARCH ORTHOP TRAUM SU, V121, P443, DOI 10.1007/s004020100266
   Cheatham ML, 2007, INTENS CARE MED, V33, P951, DOI 10.1007/s00134-007-0592-4
   Cheatham ML, 2009, CAN J SURG, V52, P315
   Cipolla J, 2005, AM SURGEON, V71, P202
   Cohen M, 2001, PLAST RECONSTR SURG, V108, P83, DOI 10.1097/00006534-200107000-00014
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   De Waele JJ, 2009, ACTA CLIN BELG, V64, P203, DOI 10.1179/acb.2009.036
   Deligiannidis N, 2008, NEW ZEAL MED J, V121, P19
   Grinnell F, 2003, TRENDS CELL BIOL, V13, P264, DOI 10.1016/S0962-8924(03)00057-6
   Horwood J, 2009, ANN ROY COLL SURG, V91, P681, DOI 10.1308/003588409X12486167520993
   Howdieshell TR, 2004, AM J SURG, V188, P301, DOI 10.1016/j.amjsurg.2004.03.007
   Hultman CS, 2005, ANN PLAS SURG, V54, P269, DOI 10.1097/01.sap.0000153084.02657.61
   *ICH, 1997, GUID GOOD CLIN PRACT
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   Kessler D, 2001, J BIOL CHEM, V276, P36575, DOI 10.1074/jbc.M101602200
   Koss W, 2009, J SURG EDUC, V66, P89, DOI 10.1016/j.jsurg.2008.12.003
   Langevin HM, 2005, AM J PHYSIOL-CELL PH, V288, pC747, DOI 10.1152/ajpcell.00420.2004
   Levy MM, 2003, CRIT CARE MED, V31, P1250, DOI 10.1097/01.CCM.0000050454.01978.3B
   Malbrain MLNG, 2006, INTENS CARE MED, V32, P1722, DOI 10.1007/s00134-006-0349-5
   Malbrain MLNG, 2006, CRIT CARE, V10, DOI 10.1186/cc4962
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Miller PR, 2002, J TRAUMA, V53, P843, DOI 10.1097/00005373-200211000-00007
   Nagy KK, 1996, AM SURGEON, V62, P331
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   Ott C, 2003, J BIOL CHEM, V278, P44305, DOI 10.1074/jbc.M309140200
   Papavramidis TS, 2009, BMC GASTROENTEROL, V9, DOI 10.1186/1471-230X-9-42
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   Reimer MW, 2008, CAN J SURG, V51, P209
   Rutherford EJ, 2004, CURR PROB SURG, V41, P816, DOI 10.1067/j.cpsurg.2004.08.003
   Scott BG, 2005, SCAND J SURG, V94, P9, DOI 10.1177/145749690509400104
   Solomkin JS, 2009, INFECT DIS CLIN N AM, V23, P593, DOI 10.1016/j.idc.2009.04.007
   Stawicki SP, 2008, INJURY, V39, P93, DOI 10.1016/j.injury.2007.06.011
   Steenvoorde P, 2006, WOUNDS, V18, P44
   Stevens P, 2009, INT WOUND J, V6, P259, DOI 10.1111/j.1742-481X.2009.00614.x
   Stonerock CE, 2003, AM SURGEON, V69, P1030
   Subramonia S, 2009, WORLD J SURG, V33, P931, DOI 10.1007/s00268-009-9947-z
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Taylor RC, 2003, J AM COLL SURGEONS, V197, P872, DOI 10.1016/S1072-7515(03)00646-X
   Tieu BH, 2008, J TRAUMA, V65, P865, DOI 10.1097/TA.0b013e31818481f1
   Tremblay LN, 2001, AM J SURG, V182, P670, DOI 10.1016/S0002-9610(01)00805-4
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
NR 47
TC 60
Z9 68
U1 0
U2 3
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0039-6060
J9 SURGERY
JI Surgery
PD NOV
PY 2010
VL 148
IS 5
BP 947
EP 953
DI 10.1016/j.surg.2010.01.021
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 676CP
UT WOS:000283888000006
PM 20227097
DA 2026-07-24
ER

PT J
AU Cowan, KN
   Teague, L
   Sue, SC
   Mahoney, JL
AF Cowan, KN
   Teague, L
   Sue, SC
   Mahoney, JL
TI Vacuum-assisted wound closure of deep sternal infections in high-risk
   patients after cardiac surgery
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID MEDIASTINITIS; STERNOTOMY
AB Background. Sternal wound infections are a serious complication arising from cardiac surgery. Recently, the general application of negative pressure to wounds by vacuum-assisted closure (VAC) therapy has shown enhanced granulation and wound contraction. Here we examine the effect of VAC on sternal wounds.
   Methods. We collected and statistically analyzed quantitative VAC performance data and outcomes with a retrospective review on a consecutive cohort of 22 patients treated with VAC for post-cardiac surgery wound complications.
   Results. Sternal wound infections became evident on average at 21.0 days after surgery, associated with dehiscence (82%), sternal instability (59%), fluid collection by computed tomography (73%), and osteomyelitis (41%). Cultures most commonly identified Staphylococcus auretts (50%). Prompt irrigation and debridement were performed on all patients, and VAC therapy was applied at approximately 7.3 days after diagnosis. Vacuum-assisted closure induced granulation of 71% of the sternal wound area by 7 days, with a daily drainage of approximately 84 mL. By 14 days, there was a 54% reduction in wound size, and patients were discharged after approximately 19.5 days and placed on home therapy. Vacuumassisted closure was discontinued at approximately 36.7 days with an average reduction in sternal wound size of 80%. Extensive secondary surgical closure, requiring muscle flaps, was avoided in 64% of patients, whereas 28% of patients required no surgical reconstruction for wound closure. No complications were related to VAC use.
   Conclusions. In contrast to our earlier studies, adjunctive VAC therapy markedly reduced required surgical interventions, reoperation for persistent infections, and the hospitalization period. Thus, VAC provides a viable and efficacious adjunctive method by which to treat postoperative wound infection after medial sternotomy.
C1 St Michaels Hosp, Div Plast Surg, Toronto, ON M5B 1W8, Canada.
   Univ Toronto, Fac Med, Toronto, ON, Canada.
C3 University of Toronto; Saint Michaels Hospital Toronto; University of
   Toronto
RP Mahoney, JL (通讯作者)，St Michaels Hosp, Div Plast Surg, Room 4-080,30 Bond St, Toronto, ON M5B 1W8, Canada.
EM james.mahoney@utoronto.ca
OI Cowan, Kyle/0000-0003-0109-7716
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bray PW, 1996, CAN J SURG, V39, P297
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Fleischmann W, 1996, UNFALLCHIRURG, V99, P283
   Francel TJ, 2001, ANN THORAC SURG, V72, P1419, DOI 10.1016/S0003-4975(00)02009-9
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   JULIAN OC, 1957, SURGERY, V42, P753
   LOOP FD, 1990, ANN THORAC SURG, V49, P179, DOI 10.1016/0003-4975(90)90136-T
   Luckraz H, 2003, J THORAC CARDIOV SUR, V125, P301, DOI 10.1067/mtc.2003.74
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Nashef SAM, 1999, EUR J CARDIO-THORAC, V16, P9, DOI 10.1016/S1010-7940(99)00134-7
NR 14
TC 76
Z9 85
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD DEC
PY 2005
VL 80
IS 6
BP 2205
EP 2212
DI 10.1016/j.athoracsur.2005.04.005
PG 8
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 993BD
UT WOS:000233926800036
PM 16305872
OA Bronze
DA 2026-07-24
ER

PT J
AU Brascia, D
   Mangiameli, G
   Marulli, G
AF Brascia, Debora
   Mangiameli, Giuseppe
   Marulli, Giuseppe
TI Complex chest wall reconstruction after failure: a literature review
SO JOURNAL OF THORACIC DISEASE
LA English
DT Review
DE Chest wall reconstruction; prosthesis; biological mesh; failure; chest
   wall tumors
ID VACUUM-ASSISTED CLOSURE; STERNAL RECONSTRUCTION; TITANIUM PLATES;
   RESECTION; INFECTION; TUMORS; BONE; STABILIZATION; OMENTUM; DEFECT
AB Background and Objective: Primary and secondary chest wall tumors (bone, breast, and soft tissue), congenital defects, and chest wall osteoradionecrosis often require extensive full-thickness local excisions to guarantee safe oncological margins (in cases of tumors) and complex reconstruction to provide stabilization and good biomechanical results avoiding postoperative respiratory failure. Thus, a personalized approach is required when dealing with chest wall defects, and reconstruction is planned. This review summarizes failed chest wall reconstruction procedures, identifies causes of failure, and highlights principles for complex chest wall reconstruction post-failure. Methods: We performed a narrative review of the literature on PubMed, Scopus, ScienceDirect, and Google Scholar, including all the relevant studies published from 1970. Key Content and Findings: The available experiences in literature are only anecdotic and no current guidelines or rules exist on this topic, also given to its rarity. Proper pre-surgical planning and a multidisciplinary team (MDT) discussion are crucial for complex cases such as infections and radiationinduced chest ulcers after previous surgical treatment. Procedures should eventually include thoracic wall debridement, necrotic tissue excision, pulse-jet lavage, prosthesis removal, and vacuum assisted closure (VAC) therapy as a bridge for chest wall re-reconstruction. Sternotomy wounds require wire and prosthesis removal, and the use of meshes or bone allografts. This review aims to summarize experiences and highlight surgical and oncologic principles for complex chest wall reconstruction after failure. Conclusions: This review summarizes literature experiences to identify common key points for chest wall reconstruction after failure and to give some advice to surgeons managing this rare, challenging surgery.
C1 [Brascia, Debora] Bari Univ Hosp, Thorac Surg Unit, Bari, Italy.
   [Brascia, Debora] Univ Bologna, Alma Mater Studiorum, Bologna, Italy.
   [Brascia, Debora; Mangiameli, Giuseppe; Marulli, Giuseppe] Humanitas Univ, Dept Biomed Sci, Via Rita Levi Montalcini 4, I-20072 Pieve Emanuele, Milan, Italy.
   [Mangiameli, Giuseppe; Marulli, Giuseppe] IRCCS Humanitas Res Hosp, Via Manzoni 56, I-20089 Rozzano, Milan, Italy.
C3 Universita degli Studi di Bari Aldo Moro; University of Bologna;
   Humanitas University
RP Marulli, G (通讯作者)，Humanitas Univ, Dept Biomed Sci, Via Rita Levi Montalcini 4, I-20072 Pieve Emanuele, Milan, Italy.; Marulli, G (通讯作者)，IRCCS Humanitas Res Hosp, Via Manzoni 56, I-20089 Rozzano, Milan, Italy.
EM giuseppe.marulli@hunimed.eu
RI Brascia, Debora/HKN-8837-2023; Mangiameli, Giuseppe/AAX-1916-2020;
   MARULLI, GIUSEPPE/LOS-8884-2024
OI Brascia, Debora/0000-0003-0860-1647; Mangiameli,
   Giuseppe/0000-0002-8394-2719; MARULLI, GIUSEPPE/0000-0001-6570-615X
CR Abbas AE, 2004, ANN THORAC SURG, V78, P1219, DOI 10.1016/j.athoracsur.2004.03.015
   Albrektsson T, 2001, EUR SPINE J, V10, pS96, DOI 10.1007/s005860100282
   Aranda Jose Luis, 2008, Interact Cardiovasc Thorac Surg, V7, P858, DOI 10.1510/icvts.2008.183905
   Arya R, 2016, J RECONSTR MICROSURG, V32, P121, DOI 10.1055/s-0035-1563395
   Bergovec M, 2022, EUR J CARDIO-THORAC, V62, DOI 10.1093/ejcts/ezac534
   Berthet JP, 2015, ANN THORAC SURG, V99, P1945, DOI 10.1016/j.athoracsur.2015.02.040
   Berthet JP, 2013, EUR J CARDIO-THORAC, V44, P866, DOI 10.1093/ejcts/ezt084
   Berthet JP, 2012, EUR J CARDIO-THORAC, V42, P444, DOI 10.1093/ejcts/ezs028
   Clermidy H, 2022, FRONT SURG, V9, DOI 10.3389/fsurg.2022.950177
   Daly AC, 2016, ADV HEALTHC MATER, V5, P2353, DOI 10.1002/adhm.201600182
   De Palma A, 2016, J THORAC DIS, V8, P490, DOI 10.21037/jtd.2016.02.64
   Dell'Amore A, 2018, J THORAC DIS, V10, pE410, DOI 10.21037/jtd.2018.06.02
   Dell'Amore A, 2012, J CARDIAC SURG, V27, P557, DOI 10.1111/j.1540-8191.2012.01518.x
   Deschamps C, 1999, J THORAC CARDIOV SUR, V117, P588, DOI 10.1016/S0022-5223(99)70339-9
   DiCocco JM, 2012, SURGERY, V151, P118, DOI 10.1016/j.surg.2011.06.034
   Dimas LS, 2013, ADV FUNCT MATER, V23, P4629, DOI 10.1002/adfm.201300215
   Endara SA, 2023, N AM SPINE SOC J, V15, DOI 10.1016/j.xnsj.2023.100243
   Gaudreau G, 2010, EUR J CARDIO-THORAC, V37, P888, DOI 10.1016/j.ejcts.2009.07.043
   Gonfiotti A, 2022, J CLIN MED, V11, DOI 10.3390/jcm11195516
   Gonfiotti A, 2010, EUR J CARDIO-THORAC, V38, P39, DOI 10.1016/j.ejcts.2009.12.046
   Haslam M, 2022, ANN THORAC SURG, V114, pE233, DOI 10.1016/j.athoracsur.2021.12.053
   Hoganson DM, 2010, BIOMATERIALS, V31, P6730, DOI 10.1016/j.biomaterials.2010.05.019
   Hosseinrezaei H, 2012, J WOUND CARE, V21, P408, DOI 10.12968/jowc.2012.21.8.408
   Kalab M, 2012, EUR J CARDIO-THORAC, V41, pe182, DOI 10.1093/ejcts/ezs077
   KING RM, 1986, ANN THORAC SURG, V41, P597, DOI 10.1016/S0003-4975(10)63067-6
   Koppert LB, 2010, ANN THORAC SURG, V90, P1102, DOI 10.1016/j.athoracsur.2010.06.044
   Listewnik MJ, 2015, ADV CLIN EXP MED, V24, P643, DOI 10.17219/acem/28111
   Marulli G, 2010, J THORAC CARDIOV SUR, V139, pE69, DOI 10.1016/j.jtcvs.2009.01.007
   McMillan RR, 2013, ANN THORAC SURG, V96, P1223, DOI 10.1016/j.athoracsur.2013.05.015
   Mirzaali MJ, 2018, NANOTECHNOLOGY, V29, DOI 10.1088/1361-6528/aad9bf
   Ng CSH, 2015, SEMIN THORAC CARDIOV, V27, P234, DOI 10.1053/j.semtcvs.2015.05.002
   Novoa Nuria, 2005, Interact Cardiovasc Thorac Surg, V4, P250, DOI 10.1510/icvts.2004.103432
   Novoa NM, 2019, Shanghai Chest, V3, P15, DOI [10.21037/shc.2019.02.02, 10.21037/shc.2019.02.02, DOI 10.21037/SHC.2019.02.02]
   Okereke IC, 2018, J THORAC CARDIOV SUR, V155, pE61, DOI 10.1016/j.jtcvs.2017.09.029
   Pang K, 2022, J PERS MED, V12, DOI 10.3390/jpm12122079
   Paris JL, 2015, ACS NANO, V9, P11023, DOI 10.1021/acsnano.5b04378
   Petrella F, 2018, Shanghai Chest, V2, P64, DOI [10.21037/shc.2018.08.02, 10.21037/shc.2018.08.02, DOI 10.21037/SHC.2018.08.02]
   Pontzer H, 2006, J EXP BIOL, V209, P57, DOI 10.1242/jeb.01971
   ROBICSEK F, 1977, J THORAC CARDIOV SUR, V73, P267
   Rocco G, 2014, ANN THORAC SURG, V98, P291, DOI 10.1016/j.athoracsur.2014.04.022
   Rocco G, 2011, SEMIN THORAC CARDIOV, V23, P307, DOI 10.1053/j.semtcvs.2012.01.011
   Shah NR, 2019, J RECONSTR MICROSURG, V35, P575, DOI 10.1055/s-0039-1688717
   Shah VN, 2018, EUR J CARDIO-THORAC, V54, P601, DOI 10.1093/ejcts/ezy055
   Shrager JB, 2003, J THORAC CARDIOV SUR, V125, P526, DOI 10.1067/mtc.2003.12
   Sim NHS, 2023, J SURG CASE REP, V2023, DOI 10.1093/jscr/rjad264
   Tricard J, 2020, J THORAC DIS, V12, P209, DOI 10.21037/jtd.2020.01.70
   Vanstraelen S, 2023, J THORAC CARDIOV SUR, V166, P1262, DOI 10.1016/j.jtcvs.2023.05.018
   Voss B, 2008, EUR J CARDIO-THORAC, V34, P139, DOI 10.1016/j.ejcts.2008.03.030
   Weyant MJ, 2006, ANN THORAC SURG, V81, P279, DOI 10.1016/j.athoracsur.2005.07.001
   Wong THY, 2022, FRONT SURG, V9, DOI 10.3389/fsurg.2022.947193
   Wouters MW, 2008, J CLIN ONCOL, V26, P5113, DOI 10.1200/JCO.2008.17.4631
   Young JA, 2023, J SURG ONCOL, V127, P336, DOI 10.1002/jso.27164
   Zhang GZ, 2016, BIOMED ENG ONLINE, V15, DOI 10.1186/s12938-016-0132-y
   Zhang QX, 1997, J SURG RES, V67, P147, DOI 10.1006/jsre.1996.4983
   Zhang X, 2024, SCI REP-UK, V14, DOI 10.1038/s41598-023-50716-x
NR 55
TC 3
Z9 4
U1 0
U2 3
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG
   00000, PEOPLES R CHINA
SN 2072-1439
EI 2077-6624
J9 J THORAC DIS
JI J. Thorac. Dis.
PD JUL
PY 2024
VL 16
IS 7
BP 4780
EP 4793
DI 10.21037/jtd-23-1431
PG 14
WC Respiratory System
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System
GA D3Y1F
UT WOS:001295564700027
PM 39144326
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Schröder, W
   Leers, JM
   Bludau, M
   Herbold, T
   Holscher, AH
AF Schroeder, W.
   Leers, J. M.
   Bludau, M.
   Herbold, T.
   Holscher, A. H.
TI Perforations near the cardia in benign diseases
SO CHIRURG
LA German
DT Article
DE Esophageal perforation; Boerhaave syndrome; Endoscopic stenting; Vacuum
   assisted closure; Esophagectomy
ID ESOPHAGEAL-PERFORATION; ANASTOMOTIC LEAK; COMPUTED-TOMOGRAPHY; CONTRAST
   SWALLOW; MANAGEMENT; IMPACT; SURGERY; OPTIONS; CLOSURE; ADULTS
AB Esophageal perforations nearby the cardia are a clinical disorder of various causes. Perforations occur most often following diagnostic or interventional endoscopy but spontaneous perforations (Boerhaave syndrome) are less frequent. Due to the heterogeneous etiology there is a broad range of therapeutic options. In most cases the esophageal perforation site can be covered by an endoscopic stent. Recent endoscopic procedures are the intraluminal application of an endoscopic vacuum-assisted closure system (endo-VAC) or clipping of the esophageal defect. Surgical procedures include direct suturing with external coverage of the defect or transhiatal blunt dissection of the esophagus without primary reconstruction. All endoscopic and surgical procedures often require an additional drainage of the mediastinum and if necessary of the thoracic and abdominal cavities. The clinical presentation ranges from a simple perforation without concomitant esophageal pathology to a defect of considerable length with pleural perforation and associated septic multiple organ failure. The severity of the septic course is the crucial parameter for the choice of the procedure. An early multiple organ failure indicates an insufficient drainage of the septic focus and is indicative for surgical resection. The overall mortality is given as 12 % in the current literature and primarily depends on the localization and the etiology of the perforation. The highest mortality rates are observed with Boerhaave syndrome. The most important prognostic variable is the time interval between perforation and initiation of therapy whereby the mortality rises up to 20 % if the interval exceeds 24 h. Due to the complex therapy and the poor prognosis esophageal perforations should be treated in specialized centers.
C1 [Schroeder, W.; Leers, J. M.; Bludau, M.; Herbold, T.; Holscher, A. H.] Univ Klin Koln, Klin Allgemein Viszeral & Tumorchirurg, D-50937 Cologne, Germany.
C3 University of Cologne
RP Schröder, W (通讯作者)，Univ Klin Koln, Klin Allgemein Viszeral & Tumorchirurg, Kerpener Str 62, D-50937 Cologne, Germany.
EM wolfgang.schroeder@uni-koeln.de
RI /AAP-2598-2021; Schröder, Wolfgang/A-8799-2008
CR Abbas G, 2009, SURGERY, V146, P749, DOI 10.1016/j.surg.2009.06.058
   Biancari F, 2013, WORLD J SURG, V37, P1051, DOI 10.1007/s00268-013-1951-7
   Bludau M, 2014, SURG ENDOSC, V28, P896, DOI 10.1007/s00464-013-3244-5
   Brinster CJ, 2004, ANN THORAC SURG, V77, P1475, DOI 10.1016/j.athoracsur.2003.08.037
   Dai YY, 2011, J THORAC CARDIOV SUR, V141, P1213, DOI 10.1016/j.jtcvs.2010.07.096
   Elsayed H, 2012, ANN ROY COLL SURG, V94, P579, DOI 10.1308/003588412X13373405388095
   Freeman RK, 2007, ANN THORAC SURG, V83, P2003, DOI 10.1016/j.athoracsur.2007.02.025
   Hagel AF, 2012, J GASTROINTEST SURG, V16, P2132, DOI 10.1007/s11605-012-1983-6
   Heits N, 2014, ANN THORAC SURG, V97, P1029, DOI 10.1016/j.athoracsur.2013.11.014
   Hogan BA, 2008, SURG ENDOSC, V22, P767, DOI 10.1007/s00464-007-9629-6
   Kirschniak A, 2011, SURG ENDOSC, V25, P2901, DOI 10.1007/s00464-011-1640-2
   Kuppusamy MK, 2011, BRIT J SURG, V98, P818, DOI 10.1002/bjs.7437
   Kurian AA, 2013, SURG ENDOSC, V27, P3910, DOI 10.1007/s00464-013-3002-8
   Leers JM, 2009, SURG ENDOSC, V23, P2258, DOI 10.1007/s00464-008-0302-5
   Lindenmann J, 2013, J GASTROINTEST SURG, V17, P1036, DOI 10.1007/s11605-012-2070-8
   Rokszin R, 2011, SURG LAPARO ENDO PER, V21, pE311, DOI 10.1097/SLE.0b013e31823118ee
   Strauss C, 2010, ANN SURG, V251, P647, DOI 10.1097/SLA.0b013e3181c1aeb8
   Vallböhmer D, 2010, DIS ESOPHAGUS, V23, P185, DOI 10.1111/j.1442-2050.2009.01017.x
   Vogel SB, 2005, ANN SURG, V241, P1016, DOI 10.1097/01.sla.0000164183.91898.74
NR 19
TC 5
Z9 5
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0009-4722
EI 1433-0385
J9 CHIRURG
JI Chirurg
PD DEC
PY 2014
VL 85
IS 12
BP 1064
EP +
DI 10.1007/s00104-014-2805-z
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AW3ES
UT WOS:000346169400004
PM 25488114
DA 2026-07-24
ER

PT J
AU Hamed, O
   Muck, PE
   Smith, JM
   Krallman, K
   Griffith, NM
AF Hamed, Osama
   Muck, Patrick E.
   Smith, J. Michael
   Krallman, Kelli
   Griffith, Nathan M.
TI Use of vacuum-assisted closure (VAC) therapy in treating lymphatic
   complications after vascular procedures: New approach for lymphoceles
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Article; Proceedings Paper
CT 36th Annual Meeting of the Society-for-Clinical-Vascular-Surgery
CY MAR 05-08, 2008
CL Las Vegas, NV
SP Soc Clin Vasc Surg
ID ARTERIAL RECONSTRUCTION; ENDOVASCULAR REPAIR; WOUND CONTROL; GROIN;
   LYMPHORRHEA; MANAGEMENT; SURGERY; SCLEROTHERAPY; FLAP; FISTULA
AB Objective: Lymphatic complications, such as lymphocutaneous fistula (LF) and lymphocele, are relatively uncommon after vascular procedures, but their treatment represents a serious challenge. Vacuum assisted closure (VAC) therapy has been reported to be an effective therapeutic option for LF, but the effectiveness of VAC therapy for lymphoceles is uncle it.
   Methods. For LF, we apply the VAC directly to the skin defect after extending it to achieve a clean wound of at least one inch in length. To treat lymphocele, we convert the lymphocele to a LF in a sterile fashion by making a one inch incision in the overlying skin and applying the VAC. The setting was a community teaching hospital. We used 10 patients that we treated with VAC therapy for LF (n = 4) and lymphoceles (n = 6).
   Results: Duration of in-patient stay, duration of in-patient VAC treatment, duration of out-patient VAC treatment, total duration of VAC treatment. The median duration of in-patient stay was 4 (range, 0-18) days, the median duration of in-patient VAC treatment was 1 (range, 0-5) days, the median duration of out-patient VAC treatment was 16 (range, 7-28) days), and the median total duration of VAC therapy was 18 (range, 13-29) days. Successful wound healing was achieved in all patients with no recurrence after VAC removal. VAC therapy for treatment of both LFs and lymphoceles resulted in early control of drainage, rapid wound closure, and short hospital stays.
   Conclusion: Our results suggest that VAC therapy is a convenient and effective therapeutic option for both LFs and lymphoceles. (J Vasc Surg 2008;48:1520-3.)
C1 [Griffith, Nathan M.] Good Samaritan Hosp, Inst Res & Educ, Cincinnati, OH 45220 USA.
   [Hamed, Osama; Muck, Patrick E.; Smith, J. Michael] Good Samaritan Hosp, Dept Gen Vasc Surg, Cincinnati, OH 45220 USA.
C3 Good Samaritan Hospital - Cincinnati; Good Samaritan Hospital -
   Cincinnati
RP Griffith, NM (通讯作者)，Good Samaritan Hosp, Inst Res & Educ, 375 Dixmyth Ave, Cincinnati, OH 45220 USA.
EM nathan_griffith@trihealth.com
RI Griffith, Nathan/JFS-3460-2023
CR Abai B, 2007, J VASC SURG, V45, P610, DOI 10.1016/j.jvs.2006.10.043
   AlSalman MMS, 1997, INT SURG, V82, P60
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Arko FR, 2002, J ENDOVASC THER, V9, P711, DOI 10.1583/1545-1550(2002)009<0711:ERREAL>2.0.CO;2
   Cannon L, 1997, EUR J VASC ENDOVASC, V14, P505, DOI 10.1016/S1078-5884(97)80133-5
   CROFT RJ, 1978, BMJ-BRIT MED J, V2, P205, DOI 10.1136/bmj.2.6131.205-a
   Demaria RG, 2003, J CARDIOVASC SURG, V44, P757
   Dosluoglu HH, 2005, J VASC SURG, V42, P989, DOI 10.1016/j.jvs.2005.07.006
   FOLK JJ, 1995, EUR J OBSTET GYN R B, V60, P191, DOI 10.1016/0028-2243(95)02044-S
   Giovannacci L, 2001, ANN VASC SURG, V15, P182, DOI 10.1007/s100160010049
   GOLDSTEIN JA, 1994, J HEART LUNG TRANSPL, V13, P549
   Greer SE, 2000, BRIT J PLAST SURG, V53, P484, DOI 10.1054/bjps.2000.3360
   Kent RC, 1996, SURGERY, V119, P378
   Kerlan RK, 1997, J VASC INTERV RADIOL, V8, P885, DOI 10.1016/S1051-0443(97)70678-X
   KHALIL IM, 1987, J VASC SURG, V6, P93, DOI 10.1067/mva.1987.avs0060093
   KWAAN JHM, 1979, ARCH SURG-CHICAGO, V114, P1416
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   PFLUG JJ, 1971, BRIT J SURG, V58, P925, DOI 10.1002/bjs.1800581216
   Pinocy J, 2003, WOUND REPAIR REGEN, V11, P104, DOI 10.1046/j.1524-475X.2003.11205.x
   Porcellini M, 2002, J CARDIOVASC SURG, V43, P217
   ROBERTS JR, 1993, AM J SURG, V165, P341, DOI 10.1016/S0002-9610(05)80839-6
   SCHWARTZ MA, 1995, AM J SURG, V170, P206, DOI 10.1016/S0002-9610(99)80287-6
   Shermak MA, 2005, PLAST RECONSTR SURG, V115, P1954, DOI 10.1097/01.PRS.0000165069.15384.E5
   SKUDDER PA, 1987, J CARDIOVASC SURG, V28, P460
   Slappy A L Jackson, 2003, Vasc Endovascular Surg, V37, P105
   SOOTS G, 1988, J CARDIOVASC SURG, V29, P42
   Stadelmann WK, 2002, PLAST RECONSTR SURG, V109, P1274, DOI 10.1097/00006534-200204010-00010
   TYNDALL SH, 1994, J VASC SURG, V19, P858, DOI 10.1016/S0741-5214(94)70011-7
   Watson DR, 2004, HEART SURG FORUM, V7, pE515, DOI 10.1532/HSF98.2004-1069
   Zuckerman DA, 1997, AM J ROENTGENOL, V169, P433, DOI 10.2214/ajr.169.2.9242748
NR 31
TC 33
Z9 39
U1 0
U2 6
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
J9 J VASC SURG
JI J. Vasc. Surg.
PD DEC
PY 2008
VL 48
IS 6
BP 1520
EP 1523
DI 10.1016/j.jvs.2008.07.059
PG 4
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery; Cardiovascular System & Cardiology
GA 388FX
UT WOS:000262006800025
PM 19118737
OA Bronze
DA 2026-07-24
ER

PT J
AU Tansarli, GS
   Vardakas, KZ
   Stratoulias, C
   Peppas, G
   Kapaskelis, A
   Falagas, ME
AF Tansarli, Giannoula S.
   Vardakas, Konstantinos Z.
   Stratoulias, Constantinos
   Peppas, George
   Kapaskelis, Anastasios
   Falagas, Matthew E.
TI Vacuum-Assisted Closure versus Closure without Vacuum Assistance for
   Preventing Surgical Site Infections and Infections of Chronic Wounds: A
   Meta-Analysis of Randomized Controlled Trials
SO SURGICAL INFECTIONS
LA English
DT Review
ID DIABETIC FOOT ULCERS; THERAPY; MULTICENTER; FRACTURES
AB Objectives: We sought to examine whether vacuum-assisted closure (VAC) is associated with fewer surgical site infections (SSIs) or infections of chronic wounds than other management procedures for surgical wounds.
   Methods: The PubMed and Scopus databases were searched systematically. Randomized controlled trials (RCTs) comparing the development of SSIs or infections of chronic wounds between patients treated with VAC for acute or chronic wounds and those whose wounds were treated without VAC were considered eligible for inclusion in the study.
   Results: Eight RCTs met the inclusion criteria for the study. Four of the studies included chronic or diabetic lower extremity wounds and four included fractures. In three of four studies reporting on fractures, the wounds were not closed post-operatively, whereas in one study primary closure of the wound was performed. With regard to wounds left open after the stabilization of fractures, patients whose wounds were treated with VAC developed fewer SSIs than those whose wounds were treated without VAC ([367 patients (196 with VAC; 171 without VAC) relative risk [RR], 0.47; 95% CI 0.28-0.81]). On the contrary, no difference in the development of SSIs occurred among patients with chronic or diabetic lower-extremity wounds treated with VAC and those whose wounds were treated without VAC ([638 patients (320 with VAC; 318 without VAC) RR 1.67; 95% CI: 0.71-3.94]).
   Conclusion: The available evidence suggests that the development of infections in wounds treated with VAC depends on the type of wound being treated.
C1 [Tansarli, Giannoula S.; Vardakas, Konstantinos Z.; Peppas, George; Kapaskelis, Anastasios; Falagas, Matthew E.] Alfa Inst Biomed Sci, Athens 15123, Greece.
   [Vardakas, Konstantinos Z.; Kapaskelis, Anastasios; Falagas, Matthew E.] IASO Gen Hosp, IASO Grp, Dept Internal Med Infect Dis, Athens, Greece.
   [Stratoulias, Constantinos] Mitera Hosp, Hygeia Grp, Dept Surg, Athens, Greece.
   [Falagas, Matthew E.] Tufts Univ, Sch Med, Dept Med, Boston, MA 02111 USA.
C3 Alfa Institute Of Biomedical Sciences; Tufts University
RP Falagas, ME (通讯作者)，Alfa Inst Biomed Sci, 19 Neapoleos St, Athens 15123, Greece.
EM m.falagas@aibs.gr
RI /M-5253-2019
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Bovill E, 2008, INT WOUND J, V5, P511, DOI 10.1111/j.1742-481X.2008.00437.x
   Brem H, 2007, J CLIN INVEST, V117, P1219, DOI 10.1172/JCI32169
   Diener H, 2009, CHIRURG, V80, P814, DOI 10.1007/s00104-009-1692-1
   Gregor S, 2008, ARCH SURG-CHICAGO, V143, P189, DOI 10.1001/archsurg.2007.54
   Highlander Peter, 2011, Foot Ankle Spec, V4, P361, DOI 10.1177/1938640011418488
   HORAN TC, 1992, AM J INFECT CONTROL, V20, P271, DOI 10.1016/S0196-6553(05)80201-9
   Jeffcoate WJ, 2004, DIABETES-METAB RES, V20, pS78, DOI 10.1002/dmrr.476
   Masden D, 2012, ANN SURG, V255, P1043, DOI 10.1097/SLA.0b013e3182501bae
   Moher D, 1998, LANCET, V352, P609, DOI 10.1016/S0140-6736(98)01085-X
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Ovington Liza, 2003, Ostomy Wound Manage, V49, P8
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Suissa D, 2011, PLAST RECONSTR SURG, V128, p498E, DOI 10.1097/PRS.0b013e31822b675c
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
NR 20
TC 3
Z9 5
U1 0
U2 5
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD AUG
PY 2014
VL 15
IS 4
BP 363
EP 367
DI 10.1089/sur.2013.028
PG 5
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA AO0PY
UT WOS:000341014100001
PM 24810943
DA 2026-07-24
ER

PT J
AU Kobayashi, T
   Mikamo, A
   Kurazumi, H
   Suzuki, R
   Shirasawa, B
   Hamano, K
AF Kobayashi, Toshiro
   Mikamo, Akihito
   Kurazumi, Hiroshi
   Suzuki, Ryo
   Shirasawa, Bungo
   Hamano, Kimikazu
TI Secondary omental and pectoralis major double flap reconstruction
   following aggressive sternectomy for deep sternal wound infections after
   cardiac surgery
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; DELAYED CLOSURE; MEDIASTINITIS; MODALITY
AB Background: Deep sternal wound infection after cardiac surgery carries high morbidity and mortality. Our strategy for deep sternal wound infection is aggressive strenal debridement followed by vacuum-assisted closure (VAC) therapy and omental-muscle flap reconstrucion. We describe this strategy and examine the outcome and long-term quality of life (QOL) it achieves.
   Methods: We retrospectively examined 16 patients treated for deep sternal wound infection between 2001 and 2007. The most recent nine patients were treated with total sternal resection followed by VAC therapy and secondary closure with omental-muscle flap reconstruction (recent group); whereas the former seven patients were treated with sternal preservation if possible, without VAC therapy, and four of these patients underwent primary closure (former group). We assessed long-term quality of life after DSWI by using the Short Form 36-Item Health Survey, Version 2 (SF36v2).
   Results: One patient died and four required further surgery for recurrence of deep sternal wound infection in the former group. The duration of treatment for deep sternal wound infection in the recent group was significantly shorter than that in previous group (63.4 +/- 54.1 days vs. 120.0 +/- 31.8 days, respectively; p = 0.039). Despite aggressive sternal resection, the QOL of patients treated for DSWI was only minimally compromised compared with age-, sex-, surgical procedures-matched patients without deep sternal wound infection.
   Conclusions: Aggressive sternal debridement followed by VAC therapy and secondary closure with an omental-muscle flap is effective for deep sternal wound infection. In this series, it resulted in a lower incidence of recurrent infection, shorter hospitalization, and it did not compromise long-term QOL greatly.
C1 [Hamano, Kimikazu] Yamaguchi Univ, Dept Surg, Div Cardiac Surg, Grad Sch Med, Yamaguchi 7558505, Japan.
   Yamaguchi Univ, Dept Clin Sci, Div Cardiac Surg, Grad Sch Med, Yamaguchi 7558505, Japan.
C3 Yamaguchi University; Yamaguchi University
RP Hamano, K (通讯作者)，Yamaguchi Univ, Dept Surg, Div Cardiac Surg, Grad Sch Med, 1-1-1 Minami Kogushi, Yamaguchi 7558505, Japan.
EM kimikazu@yamaguchi-u.ac.jp
FU Grants-in-Aid for Scientific Research [22591543] Funding Source: KAKEN
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   COLEN LB, 1989, PLAST RECONSTR SURG, V84, P936, DOI 10.1097/00006534-198912000-00011
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Fleck TM, 2004, ANN PLAS SURG, V52, P310, DOI 10.1097/01.sap.0000105524.75597.e0
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Fukuhara S, 1998, J CLIN EPIDEMIOL, V51, P1037, DOI 10.1016/S0895-4356(98)00095-X
   Fukuhara S, 1998, J CLIN EPIDEMIOL, V51, P1045, DOI 10.1016/S0895-4356(98)00096-1
   Fukuhara S., 2004, MANUAL SF 36V2 JAPAN
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Hollenbeak CS, 2000, CHEST, V118, P397, DOI 10.1378/chest.118.2.397
   Immer FF, 2005, ANN THORAC SURG, V80, P957, DOI 10.1016/j.athoracsur.2005.03.035
   Jenney AWJ, 2001, ANZ J SURG, V71, P662, DOI 10.1046/j.1445-1433.2001.02225.x
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   Klesius AA, 2004, EUR J CARDIO-THORAC, V25, P218, DOI 10.1016/j.ejcts.2003.11.019
   Lindsey JT, 2002, PLAST RECONSTR SURG, V109, P1882, DOI 10.1097/00006534-200205000-00015
   LOVICH SF, 1989, ARCH SURG-CHICAGO, V124, P1192
   Luckraz H, 2003, J THORAC CARDIOV SUR, V125, P301, DOI 10.1067/mtc.2003.74
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Schroeyers P, 2001, EUR J CARDIO-THORAC, V20, P743, DOI 10.1016/S1010-7940(01)00873-9
   SHUMACKER HB, 1963, ARCH SURG-CHICAGO, V86, P384
   Yasuura K, 1998, ANN SURG, V227, P455, DOI 10.1097/00000658-199803000-00019
NR 25
TC 26
Z9 30
U1 0
U2 0
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD APR 18
PY 2011
VL 6
AR 56
DI 10.1186/1749-8090-6-56
PG 6
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 764XX
UT WOS:000290669100001
PM 21501461
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Zhou, M
   Qi, BW
   Yu, AX
   Pan, ZY
   Zhu, SB
   Deng, K
   Tao, SX
AF Zhou, Min
   Qi, Baiwen
   Yu, Aixi
   Pan, Zhenyu
   Zhu, Shaobo
   Deng, Kai
   Tao, Shengxiang
TI VACUUM ASSISTED CLOSURE THERAPY FOR TREATMENT OF COMPLEX WOUNDS IN
   REPLANTED EXTREMITIES
SO MICROSURGERY
LA English
DT Article
ID NEGATIVE-PRESSURE; MANAGEMENT; RECONSTRUCTION; FRACTURES; INFECTION
AB The object of this study was to compare the outcomes of the vacuum assisted closure (VAC) therapy and conventional wound care with dressing change for treatment of complex wounds in patients with replantation of amputated upper and lower extremities. Data of 43 patients with replantation of amputated extremities from May 2004 to December 2011 were reviewed. There were 18 wounds of 18 patients with replantation, which were treated by dressing change and 26 wounds of 25 patients by VAC therapy. The outcomes were evaluated by the survival rate of replanted extremities, growth of granulation tissue, interval between wound treatment and secondary procedure and eventual secondary wound coverage methods. Vascular thromboses were found in 3 patients with wound treatment by dressing change and 5 by VAC. All replants of two groups of patients survived after salvage procedures. The wound score was 3.6 +/- 0.7 in the conventional dressing change group and 5.8 +/- 0.7 in the VAC group at the sixth day after treatment, respectively. The intervals between wound treatment and secondary wound coverage procedure were 12.0 +/- 1.7 days in the dressing change group and 6.1 +/- 0.7 days in the VAC group. Flaps were applied for wound coverage in 9 out of 18 (50.0%) wounds in the dressing change group and 5 out of 26 (19.2%) in the VAC group (P < 0.05), when the wounds of rest of patients were covered by the skin graft. The results showed that VAC could promote the growth of granulation tissue of wound, decrease the need of flap for wound coverage, and did not change the survival of replantation. (C) 2013 Wiley Periodicals, Inc.
C1 [Zhou, Min; Qi, Baiwen; Yu, Aixi; Pan, Zhenyu; Zhu, Shaobo; Deng, Kai; Tao, Shengxiang] Wuhan Univ, Dept Orthoped Microsurg, Zhongnan Hosp, Wuhan 430071, Hubei Province, Peoples R China.
C3 Wuhan University
RP Yu, AX (通讯作者)，Wuhan Univ, Dept Orthoped Microsurg, Zhongnan Hosp, 169 Donghu Rd, Wuhan 430071, Hubei Province, Peoples R China.
EM yuaixi666@163.com
OI Yu, Aixi/0000-0002-3751-0894
FU National Natural Science Funds of China [81171713]
FX Grant sponsor: National Natural Science Funds of China; Grant number:
   81171713.
CR Ahuja NK, 2012, MICROSURG, V32, P196, DOI 10.1002/micr.20966
   Assadian O, 2010, INT WOUND J, V7, P283, DOI 10.1111/j.1742-481X.2010.00686.x
   Battiston B, 2002, MICROSURG, V22, P187, DOI 10.1002/micr.22505
   Blume P, 2011, WOUND REPAIR REGEN, V19, P302, DOI 10.1111/j.1524-475X.2011.00669.x
   Bowler PG, 2013, J HOSP INFECT, V83, P232, DOI 10.1016/j.jhin.2012.11.018
   Cavadas PC, 2011, MICROSURG, V31, P288, DOI 10.1002/micr.20851
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Dedmond BT, 2006, J PEDIATR ORTHOPED, V26, P728, DOI 10.1097/01.bpo.0000242434.58316.ad
   Deng K, 2012, ZHONG HUA XIAN WEI W, V35, P374
   Dong ZG, 2012, MICROSURG, V32, P611, DOI 10.1002/micr.22049
   Erba P, 2011, ANN SURG, V253, P402, DOI 10.1097/SLA.0b013e31820563a8
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Jenwitheesuk K, 2012, INT WOUND J, V9, P397, DOI 10.1111/j.1742-481X.2011.00898.x
   Kamolz LP, 2004, BURNS, V30, P253, DOI 10.1016/j.burns.2003.12.003
   Kanakaris NK, 2007, INJURY, V38, pS9, DOI 10.1016/j.injury.2007.10.029
   Labler L, 2009, J TRAUMA, V66, P749, DOI 10.1097/TA.0b013e318171971a
   Lee JH, 2012, MICROSURG, V32, P431, DOI 10.1002/micr.21970
   Lioupis C, 2009, ANGIOLOGY, V60, P290, DOI 10.1177/0003319708318376
   Mo Y, 2003, SHI YONG SHOU WAI KE, V117, P111
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Murray RC, 2011, MICROSURG, V31, P104, DOI 10.1002/micr.20833
   Niu Z, 2006, ZHONG HUA XIAN WEI W, V29, P462
   Parrett BM, 2006, PLAST RECONSTR SURG, V117, P1315, DOI 10.1097/01.prs.0000204959.18136.36
   Rozen WM, 2008, J PLAST RECONSTR AES, V61, P334, DOI 10.1016/j.bjps.2007.01.064
   Schmidt WD, 2001, J INVEST DERMATOL, V116, P531, DOI 10.1046/j.1523-1747.2001.01297.x
   Stannard JP, 2010, INJURY, V41, P780, DOI 10.1016/j.injury.2009.08.011
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Yoshida S, 2011, MICROSURG, V31, P655, DOI 10.1002/micr.20932
NR 30
TC 15
Z9 18
U1 0
U2 17
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0738-1085
EI 1098-2752
J9 MICROSURG
JI Microsurgery
PD NOV
PY 2013
VL 33
IS 8
BP 620
EP 624
DI 10.1002/micr.22178
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 296LJ
UT WOS:000330186200007
PM 24307267
DA 2026-07-24
ER

PT J
AU Vos, RJ
   Yilmaz, A
   Sonker, U
   Kelder, JC
   Kloppenburg, GTL
AF Vos, Roemer J.
   Yilmaz, Alaaddin
   Sonker, Uday
   Kelder, Johannes C.
   Kloppenburg, Geoffrey T. L.
TI Primary closure using Redon drains vs vacuum-assisted closure in
   post-sternotomy mediastinitis
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article
DE VAC; Redon; Mediastinitis; Infection; Sternotomy
ID STERNAL WOUND-INFECTION; POSTSTERNOTOMY MEDIASTINITIS; POSTOPERATIVE
   MEDIASTINITIS; CONVENTIONAL TREATMENT; CARDIAC-SURGERY; RISK-FACTORS;
   MANAGEMENT; CATHETERS; THERAPY
AB Vacuum-assisted closure (VAC) is a commonly used therapy for the treatment of post-sternotomy mediastinitis. Primary closure of the sternum with high vacuum suction using Redon drains is an alternative that may reduce hospital stay. The aim of this study was to describe for the first time, the results of VAC compared with Redon drainage.
   We performed a retrospective analysis of 132 patients undergoing VAC (n = 89) or primary closure of the sternum with Redon drains (n = 43) as treatment for post-sternotomy mediastinitis between January 2000 and January 2011. Patient characteristics, risk factors and procedure-related variables were analysed. Duration of therapy, treatment failure, hospital stay and mortality as well as C-reactive protein and blood leucocyte counts on admission and at various time intervals during hospital stay were determined.
   In-hospital mortality was 12.5% in the VAC group compared with 14% in the Redon group (P = 0.96). Treatment failure in the VAC and Redon groups occurred in 28 and 23% of the patients, respectively (P = 0.68). Intensive-care stay in the VAC group was 6.8 +/- 14.4 days, and 4.8 +/- 10.1 days in the Redon group (P = 0.99). Hospitalization in the VAC group was 74 +/- 61 days and in the Redon group, 45 +/- 38 days (P = 0.0001).
   Primary closure using high vacuum suction drains is a safe and feasible treatment modality for post-sternotomy mediastinitis. It reduces hospital stay when compared with VAC therapy, without compromising mortality.
C1 [Vos, Roemer J.; Yilmaz, Alaaddin; Sonker, Uday; Kloppenburg, Geoffrey T. L.] St Antonius Hosp, Dept Cardiothorac Surg, NL-3435 CM Nieuwegein, Netherlands.
   [Kelder, Johannes C.] St Antonius Hosp, Dept Cardiol, NL-3435 CM Nieuwegein, Netherlands.
C3 St. Antonius Hospital Utrecht; St. Antonius Hospital Utrecht
RP Kloppenburg, GTL (通讯作者)，St Antonius Hosp, Dept Cardiothorac Surg, Koekoekslaan 1, NL-3435 CM Nieuwegein, Netherlands.
EM geoffrey_kloppenburg@hotmail.com
OI Vos, Roemer/0000-0002-2511-988X
CR Berg HF, 2000, ANN THORAC SURG, V70, P924, DOI 10.1016/S0003-4975(00)01524-1
   Calvat S, 1996, ANN THORAC SURG, V61, P195, DOI 10.1016/0003-4975(95)00921-3
   Davydov Iu A, 1992, Khirurgiia (Mosk), P21
   Doss M, 2002, EUR J CARDIO-THORAC, V22, P934, DOI 10.1016/S1010-7940(02)00594-8
   DURANDY Y, 1989, J THORAC CARDIOV SUR, V97, P282
   Eklund AM, 2006, ANN THORAC SURG, V82, P1784, DOI 10.1016/j.athoracsur.2006.05.097
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Ennker IC, 2011, THORAC CARDIOV SURG, V59, P15, DOI 10.1055/s-0030-1250335
   Fuchs U, 2005, ANN THORAC SURG, V79, P526, DOI 10.1016/j.athoracsur.2004.08.032
   Gummert JF, 2002, THORAC CARDIOV SURG, V50, P87, DOI 10.1055/s-2002-26691
   HORAN TC, 1992, AM J INFECT CONTROL, V20, P271, DOI 10.1016/S0196-6553(05)80201-9
   Kirsch M, 2001, ANN THORAC SURG, V71, P1580, DOI 10.1016/S0003-4975(01)02452-3
   KLUYTMANS JAJW, 1994, J HOSP INFECT, V27, P139, DOI 10.1016/0195-6701(94)90007-8
   Lu JCY, 2003, EUR J CARDIO-THORAC, V23, P943, DOI 10.1016/S1010-7940(03)00137-4
   Luckraz H, 2003, J THORAC CARDIOV SUR, V125, P301, DOI 10.1067/mtc.2003.74
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   ROBICSEK F, 1977, J THORAC CARDIOV SUR, V73, P267
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
NR 22
TC 16
Z9 21
U1 0
U2 1
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD OCT
PY 2012
VL 42
IS 4
BP E53
EP E57
DI 10.1093/ejcts/ezs404
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 018TV
UT WOS:000309687000003
PM 22885227
OA Bronze
DA 2026-07-24
ER

PT J
AU Karatepe, O
   Eken, I
   Acet, E
   Unal, O
   Mert, M
   Koc, B
   Karahan, S
   Filizcan, U
   Ugurlucan, M
   Aksoy, M
AF Karatepe, O.
   Eken, I.
   Acet, E.
   Unal, O.
   Mert, M.
   Koc, B.
   Karahan, S.
   Filizcan, U.
   Ugurlucan, M.
   Aksoy, M.
TI Vacuum Assisted Closure Improves the Quality of Life in Patients with
   Diabetic Foot
SO ACTA CHIRURGICA BELGICA
LA English
DT Article
ID EPIDEMIOLOGY; INFECTIONS; PREVALENCE
AB Background : Diabetes Mellitus (DM) is the most common endocrine disease worldwide. One of the most important chronic complications of this disease is the development of diabetic foot. The management of diabetic foot wounds is quite important with respect to public health.
   Aims : To determine the effect of Vacuum Assisted Closure (VAC) therapy on the quality of life in the treatment of diabetic foot ulcers and compare it with standart wound care.
   Methods : Between May 2007 to December 2008, 67 consecutive patients with diabetic foot ulcers were randomly assigned to VAC therapy (Group1, n : 30) or standart wound care (Group 2, n : 37). The SF-36 questionnaire was administered the day before and in the month following wound healing. Global analyses of the 8 domains and 2 comprehensive indexes of SF-36, Physical Component Summary (PCS) and Mental Component Summary (MCS) were performed.
   Clinical measures included standard antidiabetic treatment, daily wound care including antiseptic bath, debridement, toe removal for gangrene when necessary, and wound care with conventional methods or VAC. Healing time was calculated as the time from hospital admission to the time of re-epithelization.
   Results : There were no differences in the mean age, ulcer size and pulse status of the patients in both groups. Healing time in the VAC group was significantly reduced (p < 0.05). All 8 domains of SF-36 and MCS and PCS scores improved remarkably after VAC therapy.
   Conclusion : Vacuum Assited Closure therapy was found to be effective in the treatment of chronic diabetic ulcers. The improvement of quality of life demonstrates a clear-cut indication in this particular group of patients.
C1 [Karatepe, O.; Eken, I.; Acet, E.; Koc, B.; Karahan, S.] Okmeydani Training & Res Hosp, Dept Gen Surg, TR-34715 Istanbul, Turkey.
   [Unal, O.] Okmeydani Training & Res Hosp, Dept Vasc Surg, TR-34715 Istanbul, Turkey.
   [Mert, M.] Okmeydani Training & Res Hosp, Dept Endocrinol, TR-34715 Istanbul, Turkey.
   [Filizcan, U.] Maltepe Univ, Fac Med, Dept Cardiovasc Surg, Maltepe, Turkey.
   [Ugurlucan, M.] Duzce Ataturk State Hosp, Dept Cardiovasc Surg, Duzce, Turkey.
   [Aksoy, M.] Istanbul Univ, Fac Med, Dept Gen Surg, Istanbul, Turkey.
C3 Istanbul Okmeydani Training & Research Hospital; Istanbul Okmeydani
   Training & Research Hospital; Istanbul Okmeydani Training & Research
   Hospital; Maltepe University; Duzce Ataturk State Hospital; Istanbul
   University
RP Karatepe, O (通讯作者)，Okmeydani Training & Res Hosp, Dept Gen Surg, TR-34715 Istanbul, Turkey.
EM muratugurlucan@yahoo.com
RI ; Unal, Orcun/HJG-7654-2022
OI FILIZCAN, UGUR/0000-0001-5427-550X; Aksoy, Murat/0000-0002-9116-3985;
   Unal, Orcun/0000-0003-1859-8533
CR Andersen CA, 2007, SURG CLIN N AM, V87, P1149, DOI 10.1016/j.suc.2007.08.001
   [Anonymous], 1996, Current Population Reports. Population Projections of the United States by Age, Sex, Race
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   BRIDGES RM, 1994, SURG CLIN N AM, V74, P537, DOI 10.1016/S0039-6109(16)46328-0
   Calhoun Jason H, 2002, Adv Skin Wound Care, V15, P31, DOI 10.1097/00129334-200201000-00011
   Cunha BA, 1997, INFECT DIS CLIN PRAC, V10, P94
   Diamantopoulos EJ, 1998, EXP CLIN ENDOCR DIAB, V106, P346, DOI 10.1055/s-0029-1211996
   Garber A.J., 1994, DIABETES MELLITUS IN, P1391
   Hopf H W, 2001, Foot Ankle Clin, V6, P661, DOI 10.1016/S1083-7515(02)00008-6
   KING H, 1993, DIABETES CARE, V16, P157, DOI 10.2337/diacare.16.1.157
   King H, 1998, DIABETES CARE, V21, P1414, DOI 10.2337/diacare.21.9.1414
   KOLOGLU S, 1996, BASIC CLIN ENDOCRINO, P367
   Ramsey SD, 1999, DIABETES CARE, V22, P382, DOI 10.2337/diacare.22.3.382
   Reiber GE, 1996, DIABETIC MED, V13, pS6, DOI 10.1002/dme.1996.13.s1.6
   Reiber GE, 1995, DHHS PUBLICATION
   Satman I, 2002, DIABETES CARE, V25, P1551, DOI 10.2337/diacare.25.9.1551
NR 17
TC 47
Z9 49
U1 0
U2 23
PU ACTA MEDICAL BELGICA
PI BRUSSELS
PA AVENUE CIRCULAIRE 138 A, B-1180 BRUSSELS, BELGIUM
SN 0001-5458
J9 ACTA CHIR BELG
JI Acta Chir. Belg.
PD SEP-OCT
PY 2011
VL 111
IS 5
BP 298
EP 302
DI 10.1080/00015458.2011.11680757
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 847WM
UT WOS:000297003200006
PM 22191131
DA 2026-07-24
ER

PT J
AU Khashram, M
   Roake, JA
   Lewis, DR
AF Khashram, Manar
   Roake, Justin A.
   Lewis, David R.
TI The Effect of Vacuum-assisted Closure on the Tissue Oxygenation of
   Venous Ulcers: A Pilot Study
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID TENSION; DISEASE; INSUFFICIENCY; COMPRESSION; ULCERATION; LIMBS; SKIN
AB Background. Vacuum-assisted closure (V.A.C.(R) Therapy, KCI, San Antonio, TX) has been widely used to increase the healing rate of a variety of wounds. It has been hypothesized that one of the actions of VAC is to increase perfusion and subsequent oxygenation of tissue, The aim of the present study was to investigate the effect of VAC therapy on transcutaneous oximetry measurements (TCOM) of skin surrounding chronic venous ulcers, Methods. This was a prospective, experimental pilot study. Patients undergoing compression therapy were recruited from a community wound clinic. All patients had ankle-brachial pressure indices (ABPI) > 0.8. Three TCOM values were taken from around the ulcer and a reference TCOM was taken from the chest. Negative pressure was applied on the ulcer at 125-mmHg continuous subatmospheric pressure and four-layer compression bandaging over the VAC drapes. The duration of the study was 6 days. On day 6, dressings were removed and TCOM was repeated at the same skin sites. Results. Fourteen of the 17 patients completed the trial. The median age was 73 years (range 49-85). No significant difference was found in oxygen partial pressure pre-and post-VAC therapy around the ulcer site (mean 41.5 mmHg versus 40 mmHg [P = 0.671). There was a significant. difference in TCOM between the reference point and the periwound. area (mean 60.5 versus 40 [P < 0.0005]). Conclusion. This pilot study suggest that VAC therapy does not change oxygen partial pressure around venous ulcers. TCOM of the skin around ulcers were low despite normal ABPIs.
C1 [Khashram, Manar; Roake, Justin A.; Lewis, David R.] Univ Otago, Christchurch Sch Med, Dept Vasc Endovasc & Transplant Surg, Christchurch 8140, New Zealand.
C3 University of Otago
RP Khashram, M (通讯作者)，Univ Otago, Christchurch Sch Med, Dept Vasc Endovasc & Transplant Surg, POB 4345, Christchurch 8140, New Zealand.
EM manar.khashram@gmail.com
RI Khashram, Manar/H-7373-2019
OI Khashram, Manar/0000-0003-4921-8433
CR BLAIR SD, 1988, BMJ-BRIT MED J, V297, P1159, DOI 10.1136/bmj.297.6657.1159
   BROWSE NL, 1982, LANCET, V2, P243
   BYRNE P, 1984, BRIT J SURG, V71, P990
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Christenson JT, 2007, J VASC SURG, V46, P316, DOI 10.1016/j.jvs.2007.03.046
   CINA C, 1984, J VASC SURG, V1, P362, DOI 10.1067/mva.1984.avs0010362
   CLYNE CAC, 1985, BRIT J SURG, V72, P644, DOI 10.1002/bjs.1800720820
   DOWD GSE, 1987, ANN ROY COLL SURG, V69, P30
   Eklöf B, 2004, J VASC SURG, V40, P1248, DOI 10.1016/j.jvs.2004.09.027
   Fabian TS, 2000, AM SURGEON, V66, P1136
   Hopf HW, 2003, WOUND REPAIR REGEN, V11, P424, DOI 10.1046/j.1524-475X.2003.11606.x
   HUNT TK, 1988, ANN EMERG MED, V17, P1265, DOI 10.1016/j.mpsur.2017.06.004
   Jünger M, 2000, MICROCIRCULATION, V7, pS3
   Khashram M, 2009, J Wound Care, V18, P164
   KOLARI PJ, 1987, VASA-J VASCULAR DIS, V16, P312
   Loree S, 2004, J Wound Care, V13, P249
   MESSMER K, 1999, MICROCIRCULATION CHR, V23
   MOOSA HH, 1987, J CARDIOVASC SURG, V28, P464
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   NEMETH AJ, 1989, J AM ACAD DERMATOL, V20, P186, DOI 10.1016/S0190-9622(89)70019-0
   PADBERG FT, 1992, J CARDIOVASC SURG, V33, P715
   ROBSON MC, 1988, ANN EMERG MED, V17, P1274, DOI 10.1016/S0196-0644(88)80352-4
   Sheffield PJ, 1998, UNDERSEA HYPERBAR M, V25, P179
   Smart D R., 2006, Diving and Hyperbaric Medicine, V36, P72
   SMITH PDC, 1988, BMJ-BRIT MED J, V296, P1726, DOI 10.1136/bmj.296.6638.1726
   STACEY MC, 1990, BRIT J SURG, V77, P1050, DOI 10.1002/bjs.1800770932
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
NR 27
TC 3
Z9 3
U1 0
U2 1
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD SEP
PY 2009
VL 21
IS 9
BP 249
EP 253
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 507GB
UT WOS:000270839000006
PM 25903816
DA 2026-07-24
ER

PT J
AU Heller, L
   Levin, SL
   Butler, CE
AF Heller, L
   Levin, SL
   Butler, CE
TI Management of abdominal wound dehiscence using vacuum assisted closure
   in patients with compromised healing
SO AMERICAN JOURNAL OF SURGERY
LA English
DT Article
DE surgical wound dehiscence; wound healing; hernia; surgical mesh;
   surgical flaps; laparotomy; fascia; vacuum; abdomen
ID FASCIAL DEHISCENCE; INCISIONAL HERNIA; TEMPORARY CLOSURE; WALL;
   PREVENTION; OPERATIONS; ABDOMEN; FLUID
AB Background: Restoration of the abdominal wall's integrity after postoperative Wound dehiscence is frequently performed in a delayed fashion, necessitating a temporary dressing of the dehisced wound.
   Methods: The Vacuum Assisted Closure (VAC) system (Kinetic Concepts, Inc., San Antonio, TX) was used in 21 patients with postoperative abdominal wound dehiscences that could not be closed immediately and who were at high risk for healing complications. The VAC device was used in conjunction with sharp debridement and it was maintained on a continuous mode with a negative pressure of -75 to -125 mm Hg. The dressing was changed every 2 days. VAC therapy was continued until the integrity of the abdominal wall was reestablished by surgical procedures or secondary healing,
   Results: Thirteen patients had fascial dehiscence, and 9 of them had frank bowel exposure. Definitive fascial closure was performed in 9 of 13 patients with fascial dehiscence. Stable cutaneous coverage was subsequently achieved in all patients by local abdominal skin flap advancement (6), skin grafting (9), or secondary intention healing (6). Seven patients had part of their VAC therapy as outpatients. The complications included a low-output small bowel enterocutaneous fistula in 2 patients and partial skin graft loss in I patient. The fistulae resolved after operative treatment (1) or conservative treatment (1). Conclusion: Integration of the VAC system in the management of post-laparotomty wound dehiscence in patients with compromised wound healing appears to be successful and should be considered in such patients to provide a stable, healed wound. (c) 2006 Excerpta Medica Inc. All rights reserved.
C1 Univ Texas, MD Anderson Canc Ctr, Dept Plast Surg, Unit 443, Houston, TX 77230 USA.
   Duke Univ, Med Ctr, Dept Plast Surg, Durham, NC USA.
C3 University of Texas System; UTMD Anderson Cancer Center; Duke University
RP Butler, CE (通讯作者)，Univ Texas, MD Anderson Canc Ctr, Dept Plast Surg, Unit 443, POB 301402, Houston, TX 77230 USA.
EM cbutler@mdanderson.org
RI Butler, Charles/GOH-1645-2022
CR AKERS DL, 1991, J VASC SURG, V14, P48
   BROCK WB, 1995, AM SURGEON, V61, P30
   CAFFEE HH, 1983, PLAST RECONSTR SURG, V71, P348, DOI 10.1097/00006534-198303000-00010
   EMMONS SL, 1988, OBSTET GYNECOL, V72, P559
   FANSLER RF, 1995, AM J SURG, V170, P15, DOI 10.1016/S0002-9610(99)80244-X
   Fox V J, 1999, AORN J, V69, P530, DOI 10.1016/S0001-2092(06)62464-2
   GISLASON H, 1995, EUR J SURG, V161, P349
   GREENBURG AG, 1979, ARCH SURG-CHICAGO, V114, P143
   HADDAD V, 1980, AM SURGEON, V46, P508
   HESSELINK VJ, 1993, SURG GYNECOL OBSTET, V176, P228
   *KCI VAC, 2004, THER CLIN GUID
   McNeeley SG, 1998, AM J OBSTET GYNECOL, V179, P1430, DOI 10.1016/S0002-9378(98)70006-7
   MIZRAHI S, 1993, AM J SURG, V166, P62, DOI 10.1016/S0002-9610(05)80585-9
   Morykwas M J, 1997, J South Orthop Assoc, V6, P279
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   PENNINCKX FM, 1979, ANN SURG, V189, P345, DOI 10.1097/00000658-197903000-00016
   POOLE GV, 1984, AM SURGEON, V50, P569
   POOLE GV, 1985, SURGERY, V97, P631
   REITAMO J, 1972, ACTA CHIR SCAND, V138, P170
   RIOU JPA, 1992, AM J SURG, V163, P324, DOI 10.1016/0002-9610(92)90014-I
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Schimp VL, 2004, GYNECOL ONCOL, V92, P586, DOI 10.1016/j.ygyno.2003.10.055
   SCHMIDT U, 1994, BRIT J ANAESTH, V73, P204, DOI 10.1093/bja/73.2.204
   Sherck J, 1998, AM SURGEON, V64, P854
   STONE HH, 1981, ANN SURG, V193, P612, DOI 10.1097/00000658-198105000-00011
   Stonerock CE, 2003, AM SURGEON, V69, P1030
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   WYSOCKI AB, 1993, J INVEST DERMATOL, V101, P64, DOI 10.1111/1523-1747.ep12359590
   WYSOCKI AB, 1990, LAB INVEST, V63, P825
NR 29
TC 79
Z9 94
U1 0
U2 7
PU EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
PI BRIDGEWATER
PA 685 ROUTE 202-206 STE 3, BRIDGEWATER, NJ 08807 USA
SN 0002-9610
EI 1879-1883
J9 AM J SURG
JI Am. J. Surg.
PD FEB
PY 2006
VL 191
IS 2
BP 165
EP 172
DI 10.1016/j.amjsurg.2005.09.003
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 010TQ
UT WOS:000235221200005
PM 16442940
DA 2026-07-24
ER

PT J
AU Scherer, LA
   Shiver, S
   Chang, M
   Meredith, JW
   Owings, JT
AF Scherer, LA
   Shiver, S
   Chang, M
   Meredith, JW
   Owings, JT
TI The vacuum assisted closure device - A method of securing skin grafts
   and improving graft survival
SO ARCHIVES OF SURGERY
LA English
DT Article; Proceedings Paper
CT 73rd Annual Meeting of the Pacific-Coast-Surgical-Association
CY FEB 16-18, 2002
CL LAS VEGAS, NEVADA
SP Pacific Coast Surg Assoc
ID NEGATIVE-PRESSURE DRESSINGS; WOUND CONTROL; FIXATION; BOLSTER
AB Hypothesis: Use of the vacuum assisted closure device (VAC) for securing split-thickness skin grafts (STSGs) is associated with improved wound outcomes compared with bolster dressings.
   Design: Consecutive case series.
   Patients and Setting: Consecutive patients at a level I trauma center requiring STSG due to traumatic or thermal tissue loss during an 18-month period.
   Main Outcome Measure: Repeated skin grafting due to failure of the initial graft. Secondary outcome measures included dressing-associated complications, percentage of graft take, and length of hospital stay.
   Results: Sixty-one patients underwent STSG placement. Indications for STSG were burn injury (n=32), soft tissue loss (n=27), and fasciotomy-site coverage (n=2). Patients were treated with the VAC (n=34) or the bolster dressing (n=27). The VAC group required significantly fewer repeated STSGs (1 [3%] vs 5 [19%]; P=.04). Two additional graft failures occurred in the no-VAC group, but repeated STSGs were refused by these patients. No difference was seen between the groups in age, percentage of graft take, or hospital length of stay. The no-VAC group had significantly larger grafts (mean +/- SD, 984 996 vs 386 573 cm(2); P=.006). The patients requiring repeated STSGs (n=6) did not have significantly larger grafts than those not requiring repeated STSGs (mean +/- SD, 617+/-717 vs 658+/-857 cm(2); P=.62). No dressing-associated complications occurred in the VAC group.
   Conclusions: The VAC provides a safe and effective method for securing STSGs and is associated with improved graft survival as measured by a reduction in number of repeated STSGs.
C1 Univ Calif Davis, Med Ctr, Dept Surg, Sacramento, CA 95817 USA.
   Wake Forest Univ, Baptist Med Ctr, Dept Surg, Winston Salem, NC 27109 USA.
C3 University of California System; University of California Davis; Wake
   Forest University; Wake Forest Baptist Medical Center
RP Scherer, LA (通讯作者)，Univ Calif Davis, Med Ctr, Dept Surg, 2315 Stockton Blvd,Room 4209, Sacramento, CA 95817 USA.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BEST T, 1995, J TRAUMA, V38, P915, DOI 10.1097/00005373-199506000-00016
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Deva AK, 2000, MED J AUSTRALIA, V173, P128, DOI 10.5694/j.1326-5377.2000.tb125564.x
   DYSON M, 1992, J INVEST DERMATOL, V99, P729, DOI 10.1111/1523-1747.ep12614460
   Elwood ET, 2001, ANN PLAS SURG, V46, P49, DOI 10.1097/00000637-200101000-00010
   Fullerton JK, 2000, ANN PLAS SURG, V45, P462, DOI 10.1097/00000637-200045040-00022
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   Ghosh SJ, 1997, BURNS, V23, P601, DOI 10.1016/S0305-4179(97)00066-1
   Hansbrough Wendy, 1995, Journal of Burn Care and Rehabilitation, V16, P531, DOI 10.1097/00004630-199509000-00012
   Langtry JAA, 1998, DERMATOL SURG, V24, P1350, DOI 10.1111/j.1524-4725.1998.tb00013.x
   Maggi SP, 1999, BURNS, V25, P237, DOI 10.1016/S0305-4179(98)00160-0
   Molnar JA, 2000, PLAST RECONSTR SURG, V105, P174, DOI 10.1097/00006534-200001000-00030
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Sposato G, 2001, BRIT J PLAST SURG, V54, P235, DOI 10.1054/bjps.2000.3537
   Wolf Y, 1998, ANN PLAS SURG, V40, P149, DOI 10.1097/00000637-199802000-00008
NR 16
TC 237
Z9 290
U1 1
U2 20
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 515 N STATE ST, CHICAGO, IL 60610 USA
SN 0004-0010
J9 ARCH SURG-CHICAGO
JI Arch. Surg.
PD AUG
PY 2002
VL 137
IS 8
BP 930
EP 933
DI 10.1001/archsurg.137.8.930
PG 4
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 582AE
UT WOS:000177326900014
PM 12146992
DA 2026-07-24
ER

PT J
AU Beidas, OE
   Gusenoff, JA
AF Beidas, Omar E.
   Gusenoff, Jeffrey A.
TI Deep and Superficial Closure
SO AESTHETIC SURGERY JOURNAL
LA English
DT Article
ID PRESSURE WOUND THERAPY; SUBCUTICULAR SUTURES; BARBED SUTURES; SKIN
   CLOSURE; PATIENT; STAPLES; ABDOMINOPLASTY; INFECTION; DERMABOND;
   INCISION
AB All operative interventions in plastic surgery have one thing in common: closure of an incision or wound at the conclusion of the procedure. For many years, the only option to accomplish this task was the use of sutures. Today's surgeon, however, has many more options available, ranging from smooth to barbed suture, external to internal staples, internal to external adhesive glues, and incisional negative-pressure wound therapy. These devices are designed with the goal of making wound closure more rapid and secure, and decreasing postoperative sequelae. This paper reviews methods available to perform incisional closure and the published clinical data regarding their use.
C1 [Beidas, Omar E.; Gusenoff, Jeffrey A.] Univ Pittsburgh, Dept Plast Surg, Pittsburgh, PA USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); University
   of Pittsburgh
RP Gusenoff, JA (通讯作者)，3380 Blvd Allies,Suite 138, Pittsburgh, PA 15213 USA.
EM gusenoffja@upmc.edu
RI Beidas, Omar/NCV-7763-2025
FU Ethicon US, LLC (Somerville, NJ, USA)
FX This supplement is sponsored by Ethicon US, LLC (Somerville, NJ, USA).
CR [Anonymous], KNOTL TISS CLOS DEV
   [Anonymous], INSORB ABS SKIN STAP
   Bhende Shubhangi, 2002, Surg Infect (Larchmt), V3, P251, DOI 10.1089/109629602761624216
   Bron T, 2016, AESTHET SURG J, V36, P459, DOI 10.1093/asj/sjv224
   Cross KJ, 2009, PLAST RECONSTR SURG, V124, P156, DOI 10.1097/PRS.0b013e3181a805c5
   Custis T, 2015, JAMA DERMATOL, V151, P862, DOI 10.1001/jamadermatol.2015.0174
   de Luis DA, 2014, NUTR HOSP, V30, P509
   Draaijers LJ, 2004, PLAST RECONSTR SURG, V113, P1960, DOI 10.1097/01.PRS.0000122207.28773.56
   Ergin Omer Naci, 2017, J Orthop Case Rep, V7, P50, DOI 10.13107/jocr.2250-0685.802
   Fleisher J, 2019, J MATERN-FETAL NEO M, V32, P3830, DOI 10.1080/14767058.2018.1474870
   Glennie RA, 2017, J ARTHROPLASTY, V32, P2431, DOI 10.1016/j.arth.2017.02.042
   Grauhan O, 2014, INT WOUND J, V11, P6, DOI 10.1111/iwj.12294
   Hendrickx BIMM, 2018, J PLAST RECONSTR AES, V71, P900, DOI 10.1016/j.bjps.2018.01.030
   Horch RE, 2015, J WOUND CARE, V24, P21, DOI 10.12968/jowc.2015.24.Sup4b.21
   Hurwitz DJ, 2013, AESTHET SURG J, V33, p44S, DOI 10.1177/1090820X13498506
   Hwang K, 2015, J CRANIOFAC SURG, V26, pE48, DOI 10.1097/SCS.0000000000001311
   Isaac KV, 2017, AESTHET SURG J, V37, P428, DOI 10.1093/asj/sjw241
   Koonce SL, 2015, ANN PLAS SURG, V74, P107, DOI 10.1097/SAP.0b013e318289856f
   Leaper DJ, 2006, BMJ-BRIT MED J, V332, P532, DOI 10.1136/bmj.332.7540.532
   Liu XM, 2017, J AM ACAD DERMATOL, V77, P911, DOI 10.1016/j.jaad.2017.04.1128
   LOCKWOOD T, 1993, PLAST RECONSTR SURG, V92, P1112, DOI 10.1097/00006534-199311000-00018
   Madsen AM, 2015, OBSTET GYNECOL, V125, p26S, DOI 10.1097/01.aog.0000462740.31130.62
   Meng FJ, 2017, ANN PLAS SURG, V79, P197, DOI 10.1097/SAP.0000000000001043
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Pineros-Fernandez Angela, 2006, J Long Term Eff Med Implants, V16, P19
   Rubin JP, 2014, AESTHET SURG J, V34, P272, DOI 10.1177/1090820X13519264
   SANDERS RJ, 1977, ARCH SURG-CHICAGO, V112, P1188
   Sharma C, 2014, ARCH GYNECOL OBSTET, V290, P655, DOI 10.1007/s00404-014-3274-9
   Yazdany T, 2010, INT UROGYNECOL J, V21, P813, DOI 10.1007/s00192-010-1109-1
   Yu LL, 2018, AM J OBSTET GYNECOL, V218, P200, DOI 10.1016/j.ajog.2017.09.017
NR 30
TC 3
Z9 4
U1 0
U2 8
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1090-820X
EI 1527-330X
J9 AESTHET SURG J
JI Aesthet. Surg. J.
PD APR
PY 2019
VL 39
SU 2
BP S85
EP S93
DI 10.1093/asj/sjy208
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HQ6RP
UT WOS:000462546000004
PM 30869753
DA 2026-07-24
ER

PT J
AU Nikolic, H
   Versic, AB
   Cepic, I
   Hasandic, D
   Medancic, SS
   Miletic, D
   Tadin, T
   Persic, M
AF Nikolic, Harry
   Versic, Ana Bosak
   Cepic, Ivica
   Hasandic, Damir
   Medancic, Suzana Srsen
   Miletic, Damir
   Tadin, Tomislav
   Persic, Mladen
TI Psoas abscess as the first manifestation of Crohn's disease - case
   report
SO SIGNA VITAE
LA English
DT Article
DE child; Crohn's disease; psoas abscess
ID ILIOPSOAS ABSCESS; DIAGNOSIS
AB A case of 16-year-old female with secondary psoas abscess as the complication of the Crohn's disease was analysed. Her pre-hospital, long lasting, non-specific symptoms led to ultrasound (US) and radiologic imaging confirming the diagnosis. The antibiotic treatment was insufficient and worsening of the patient's condition required surgical treatment including descendent colectomy, abscess drainage and negative pressure wound therapy (NPWT). In spite of numerous complications the condition of the child gradually unproved and she was discharged from the hospital on the 71st postoperative day. Two years after the colectomy, the occlusion of her colostomy was performed.
C1 [Nikolic, Harry; Versic, Ana Bosak; Hasandic, Damir; Medancic, Suzana Srsen] Univ Hosp Rijeka, Pediat Surg Dept, Rijeka, Croatia.
   [Cepic, Ivica] Univ Hosp Rijeka, Gen Surg Dept, Rijeka, Croatia.
   [Miletic, Damir] Univ Hosp Rijeka, Dept Radiol, Rijeka, Croatia.
   [Tadin, Tomislav] Hlth Ctr Rijeka, Ultrasound Diagnost Serv, Rijeka, Croatia.
   [Persic, Mladen] Univ Hosp Rijeka, Pediat Dept, Rijeka, Croatia.
C3 University of Rijeka; University of Rijeka; University of Rijeka;
   University of Rijeka
RP Tadin, T (通讯作者)，Ultrasound Diagnost Serv, Martina Kontusa 18, Rijeka 51000, Croatia.
EM medicina_ri@inet.hr
RI Miletic, Damir/R-5132-2018
CR AGHA FP, 1985, AM J GASTROENTEROL, V80, P924
   Chern CH, 1997, AM J EMERG MED, V15, P83, DOI 10.1016/S0735-6757(97)90057-7
   FEMMININEO AF, 1988, ARCH PHYS MED REHAB, V69, P223
   Huang JJ, 2000, J INFECTION, V40, P248, DOI 10.1053/jinf.2000.0643
   Koubaa M, 2013, INT J CASE REPORTS M, V2013, DOI 10.5171/2013.507024
   Marín I, 2009, GASTROENT HEPAT-BARC, V32, P557, DOI 10.1016/j.gastrohep.2009.03.004
   RICCI MA, 1985, AM J GASTROENTEROL, V80, P970
   Richards RJ, 2011, WORLD J GASTRO ENDOS, V3, P209, DOI 10.4253/wjge.v3.i11.209
   Shields D, 2012, INT J SURG, V10, P466, DOI 10.1016/j.ijsu.2012.08.016
   Veroux M, 2004, ACTA CHIR BELG, V104, P187, DOI 10.1080/00015458.2004.11679533
NR 10
TC 1
Z9 1
U1 0
U2 3
PU PHARMAMED MADO LTD
PI ZAGREB
PA ZATISJE 8 G, ZAGREB, 10000, CROATIA
SN 1334-5605
J9 SIGNA VITAE
JI Signa Vitae
PY 2018
VL 14
IS 2
BP 78
EP 79
DI 10.22514/SV142.112018.13
PG 2
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA GZ5KV
UT WOS:000449460400013
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Kindel, N
AF Kindel, Nicole
TI Improvised Skin Graft for a Large Superficial Hematoma A Case
   Study
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Hematoma; Hematoma treatment; Large hematoma; Superficial hematoma;
   Surgical management
AB BACKGROUND: Management of a hematoma is challenging when its size is substantial.
   CASE: This case report describes the successful surgical treatment of a large, superficial hematoma with an improvised skin graft and negative pressure wound therapy.
   CONCLUSIONS: We have found that using the patient's own skin for a skin graft may provide adequate wound coverage and decrease healing time. This method also eliminates the need for creating a donor site. This same procedure can be used on smaller lacerations or skin tears. We advocate detaching the skin flap completely before reattaching in order to prevent reperfusion injury and necrosis.
C1 [Kindel, Nicole] Kaiser Westside Med Ctr, 2875 NW Stucki Ave, Hillsboro, OR 97124 USA.
RP Kindel, N (通讯作者)，Kaiser Westside Med Ctr, 2875 NW Stucki Ave, Hillsboro, OR 97124 USA.
CR Chiummariello S, 2013, WOUNDS, V25, P324
   Daggett JR, 2013, INT J SURG CASE REP, V4, P1080, DOI 10.1016/j.ijscr.2013.07.036
   Limberg RM, 2011, J EMERGENCY MED, V41, P1
   Moradian S, 2016, INT WOUND J, V13, P283, DOI 10.1111/iwj.12426
   Pagan M, 2011, WOUND PRACT RES, V19, P20
   Vandervord JG, 2016, INT WOUND J, V13, P59, DOI 10.1111/iwj.12227
NR 6
TC 2
Z9 2
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD SEP-OCT
PY 2017
VL 44
IS 5
BP 492
EP 494
DI 10.1097/WON.0000000000000364
PG 3
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA FG2OA
UT WOS:000409948400017
PM 28777123
DA 2026-07-24
ER

PT J
AU Flynn, RL
   Chowdhury, MH
   Rudolph, J
   Einstein, S
AF Flynn, Rod L.
   Chowdhury, Mashiul H.
   Rudolph, Joseph
   Einstein, Stephanie
TI Rare Presentation of Postsurgical Pyoderma Gangrenosum Presenting as
   Necrotizing Soft Tissue Infection
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Editorial Material
DE antibiotics; antimicrobial dressings; cellulitis; colorectal surgery;
   necrotizing soft tissue infection; negative-pressure wound therapy;
   pyoderma gangrenosum; steroids; surgical debridement; tissue necrosis
ID ULCERATIVE-COLITIS; MANAGEMENT; THERAPY
AB Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic dermatosis believed to be mediated by an autoimmune reaction. Typical treatment includes autolytic debridement, management of exudate, protection from trauma, and steroid therapy. A diagnosis of exclusion, PG is frequently mistaken for a wound infection, but antibiotics do not alleviate the condition. Incision and debridement has been observed to cause further spread of the lesions because of pathergy resulting from the additional trauma. This case report describes a patient who was misdiagnosed with necrotic soft tissue infection that was actually postsurgical PG.
C1 [Flynn, Rod L.] Christ Hosp, Surg Oncol, Cincinnati, OH 45219 USA.
   [Chowdhury, Mashiul H.] Canc Treatment Ctr Amer, Infect Dis, Philadelphia, PA USA.
   [Rudolph, Joseph; Einstein, Stephanie] Canc Treatment Ctr Amer, Dept Skin Wound & Ostomy Care, Philadelphia, PA USA.
C3 Christ Hospital - Ohio
RP Flynn, RL (通讯作者)，Christ Hosp, Surg Oncol, Cincinnati, OH 45219 USA.
CR Aggarwal S., 2012, PRIM HLTH CARE, V22, P26, DOI DOI 10.7748/PHC2012.06.22.5.26.C9125
   Ahronowitz I, 2012, AM J CLIN DERMATOL, V13, P191, DOI 10.2165/11595240-000000000-00000
   Anaya DA, 2005, ARCH SURG-CHICAGO, V140, P151, DOI 10.1001/archsurg.140.2.151
   Baglieri F, 2010, DERMATOL THER, V23, P541, DOI 10.1111/j.1529-8019.2010.01357.x
   Binus AM, 2011, BRIT J DERMATOL, V165, P1244, DOI 10.1111/j.1365-2133.2011.10565.x
   Fraccalvieri M, 2014, INT WOUND J, V11, P164, DOI 10.1111/j.1742-481X.2012.01058.x
   Guo H, 2013, CHINESE MED J-PEKING, V126, P1798, DOI 10.3760/cma.j.issn.0366-6999.20130032
   Marzano AV, 2014, INFLAMM BOWEL DIS, V20, P213, DOI 10.1097/01.MIB.0000436959.62286.f9
   Miller J, 2010, J AM ACAD DERMATOL, V62, P646, DOI 10.1016/j.jaad.2009.05.030
   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
   Su WPD, 2004, INT J DERMATOL, V43, P790, DOI 10.1111/j.1365-4632.2004.02128.x
   Tolkachjov SN, 2015, J AM ACAD DERMATOL, V73, P615, DOI 10.1016/j.jaad.2015.06.054
   Wong WW, 2011, J CUTAN MED SURG, V15, P322, DOI 10.2310/7750.2011.10119
   Zuo KJ, 2015, J PLAST RECONSTR AES, V68, P295, DOI 10.1016/j.bjps.2014.12.036
NR 14
TC 6
Z9 7
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD NOV
PY 2019
VL 32
IS 11
BP 507
EP 511
DI 10.1097/01.ASW.0000579692.74662.bb
PG 5
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA JZ6OD
UT WOS:000505222100007
PM 31498172
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Zheng, YR
   Wang, XG
   Zhang, LP
   You, CG
   Feng, ZZ
   Han, CM
AF Zheng, Yurong
   Wang, Xingang
   Zhang, Liping
   You, Chuangang
   Feng, Zhanzeng
   Han, Chunmao
TI Successful Treatment of a Patient With Complicated Diabetic Foot Wound:
   A Case Report
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE diabetic foot; multimodal therapies; patient compliance
ID DRESSINGS; DISEASE; ULCERS
AB Foot ulceration is one of the most serious complications of diabetes mellitus and may lead to amputation of the lower extremity. Timely prophylaxis and treatment of diabetic foot ulceration are important to maintain a good quality of life. This article reports a complicated diabetic patient with severe limb-threatening necrotizing infection. We successfully applied endovascular stent insertion, digit amputation, negative pressure wound therapy, and advanced dressings in different wound phases to achieve definitive wound healing after 12 months of treatment. Based on this case report, we would like to emphasize the importance of combined multiple therapies and patient compliance for severe diabetic foot ulcers.
C1 [Zheng, Yurong; Wang, Xingang; Zhang, Liping; You, Chuangang; Feng, Zhanzeng; Han, Chunmao] Zhejiang Univ, Affiliated Hosp 2, Hangzhou 310009, Zhejiang, Peoples R China.
C3 Zhejiang University
RP Han, CM (通讯作者)，Zhejiang Univ, Affiliated Hosp 2, Coll Med, 88 Jiefang Rd, Hangzhou 310009, Zhejiang, Peoples R China.
EM hanchunmao1@126.com
OI Zheng, Yurong/0000-0002-1224-4796
CR Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Barnea Y, 2010, THER CLIN RISK MANAG, V6, P21
   Beckman JA, 2002, JAMA-J AM MED ASSOC, V287, P2570, DOI 10.1001/jama.287.19.2570
   Bourguignon LYW, 2006, J INVEST DERMATOL, V126, P1356, DOI 10.1038/sj.jid.5700260
   Broughton G, 2006, PLAST RECONSTR SURG, V117, p12S, DOI 10.1097/01.prs.0000225430.42531.c2
   Dubsky M, 2013, INT WOUND J, V10, P555, DOI 10.1111/j.1742-481X.2012.01022.x
   Dyet JF, 2000, DIABETES-METAB RES, V16, pS16, DOI 10.1002/1520-7560(200009/10)16:1+<::AID-DMRR131>3.3.CO;2-N
   Frykberg RG, 2015, INT WOUND J, V12, P53, DOI 10.1111/iwj.12050
   Gregg EW, 2004, DIABETES CARE, V27, P1591, DOI 10.2337/diacare.27.7.1591
   Hilton JR, 2004, CLIN INFECT DIS, V39, pS100, DOI 10.1086/383270
   Hobizal KB, 2012, DIABET FOOT ANKLE, V3, DOI 10.3402/dfa.v3i0.18409
   Jeffcoate WJ, 2003, LANCET, V361, P1545, DOI [10.1001/jama.2018.18323, 10.1001/jama.2018.18323]
   Kota Siva Krishna, 2013, J Cardiovasc Dis Res, V4, P79, DOI 10.1016/j.jcdr.2012.10.002
   Lewis TV, 1999, ARTERIOSCL THROM VAS, V19, P2782, DOI 10.1161/01.ATV.19.11.2782
   McLennan S, 2006, WOUND PRACT RES, V14, P8
   Schaper NC, 2012, DIABETES-METAB RES, V28, P218, DOI 10.1002/dmrr.2255
   Schaper Nicolaas C, 2003, Curr Diab Rep, V3, P475, DOI 10.1007/s11892-003-0010-4
   Singh N, 2005, JAMA-J AM MED ASSOC, V293, P217, DOI 10.1001/jama.293.2.217
   Thomas S, 2008, INT WOUND J, V5, P602, DOI 10.1111/j.1742-481X.2008.00541.x
   Toobert DJ, 2000, DIABETES CARE, V23, P943, DOI 10.2337/diacare.23.7.943
   Vaneau M, 2007, ARCH DERMATOL, V143, P1291, DOI 10.1001/archderm.143.10.1291
NR 21
TC 2
Z9 3
U1 2
U2 11
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD JUN
PY 2014
VL 13
IS 2
BP 140
EP 146
DI 10.1177/1534734614529650
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA AJ3NW
UT WOS:000337574600012
PM 24743750
DA 2026-07-24
ER

PT J
AU Cramer, P
   Schneider-Burrus, S
   Kovács, M
   Scholl, L
   Podda, M
   Bechara, FG
AF Cramer, P.
   Schneider-Burrus, S.
   Kovacs, M.
   Scholl, L.
   Podda, M.
   Bechara, F. G.
TI Hidradenitis suppurativa /acne inversa-surgical options, reconstruction
   and combinations with drug therapies-an update
SO HAUTARZT
LA German
DT Article
DE Reconstructive surgical procedures; Immunomodulation; Wound healing;
   Negative-pressure wound therapy; Recurrence rate
ID TISSUE-SPARING EXCISION; AXILLARY HIDRADENITIS; INVERSA/HIDRADENITIS
   SUPPURATIVA; WIDE EXCISION; SURGERY; GLUTEAL; MANAGEMENT; EFFICACY;
   CLOSURE; GROIN
AB Hidradenitis suppurativa/acne inversa (HS/AI) is a chronic inflammatory skin disease whose treatment includes both conservative and surgical treatment options. In Hurley stages II and III, surgical resection of irreversibly destroyed tissue should be the objective. For this purpose several resection techniques exist, which differ primarily with regard to their invasiveness and tendency to recur. To date, there is no generally accepted consensus on the use of different resection and reconstruction techniques or the inclusion of drug therapies in the overall therapeutic concept.
C1 [Cramer, P.; Scholl, L.; Bechara, F. G.] Klin Ruhr Univ Bochum, St Josef Hosp, Katholisches Klin Bochum, Klin Dermatol Venerol & Allergol, Gudrunstr 56, D-44791 Bochum, Germany.
   [Schneider-Burrus, S.] Havelklin Berlin, Zentrum Dermatochirurg, Berlin, Germany.
   [Kovacs, M.; Podda, M.] Goethe Univ Frankfurt, Hautklin Klin Darmstadt, Akad Lehrkrankenhaus, Darmstadt, Germany.
C3 Ruhr University Bochum; Goethe University Frankfurt
RP Bechara, FG (通讯作者)，Klin Ruhr Univ Bochum, St Josef Hosp, Katholisches Klin Bochum, Klin Dermatol Venerol & Allergol, Gudrunstr 56, D-44791 Bochum, Germany.
EM falk.bechara@klinikum-bochum.de
OI Schneider-Burrus, Sylke/0000-0002-9740-6845
CR Aksakal AB, 2008, DERMATOL SURG, V34, P228, DOI 10.1111/j.1524-4725.2007.34042.x
   Albrecht J, 2019, BRIT J DERMATOL, V180, P749, DOI 10.1111/bjd.17265
   Alikhan A, 2019, J AM ACAD DERMATOL, V81, P76, DOI 10.1016/j.jaad.2019.02.067
   Alikhan A, 2019, J AM ACAD DERMATOL, V81, P91, DOI 10.1016/j.jaad.2019.02.068
   Altmann S, 2001, CHIRURG, V72, P1413, DOI 10.1007/s001040170004
   Andersen RK, 2017, CLIN DERMATOL, V35, P218, DOI 10.1016/j.clindermatol.2016.10.018
   ANDERSON BB, 1982, J NATL MED ASSOC, V74, P999
   André R, 2019, INT J DERMATOL, V58, pE208, DOI 10.1111/ijd.14596
   Argyropoulou M, 2019, BRIT J DERMATOL, V180, P1161, DOI 10.1111/bjd.17151
   ARIYAN S, 1976, PLAST RECONSTR SURG, V58, P44, DOI 10.1097/00006534-197607000-00007
   Ather Shahzad, 2006, Int Wound J, V3, P159, DOI 10.1111/j.1742-481X.2006.00235.x
   Balik E, 2009, WORLD J SURG, V33, P481, DOI 10.1007/s00268-008-9845-9
   BANERJEE AK, 1992, BRIT J SURG, V79, P863, DOI 10.1002/bjs.1800790905
   Bechara FG, 2016, EXP DERMATOL, V25, P8
   Bechara Falk G, 2016, MMW Fortschr Med, V158, P52, DOI [10.1007/s15006-016-8662-6, 10.1007/s15006-016-8662-6]
   Bettoli V, 2019, J EUR ACAD DERMATOL, V33, P930, DOI 10.1111/jdv.15332
   Bieniek A, 2010, DERMATOL SURG, V36, P1998, DOI 10.1111/j.1524-4725.2010.01763.x
   Bilali Sokol, 2012, Acta Chir Iugosl, V59, P91
   Blok JL, 2015, J EUR ACAD DERMATOL, V29, P379, DOI 10.1111/jdv.12376
   Bocchini SF, 2003, DIS COLON RECTUM, V46, P944, DOI 10.1007/s10350-004-6691-1
   BROADWATER JR, 1982, AM J SURG, V144, P668, DOI 10.1016/0002-9610(82)90547-5
   Büyükasik O, 2011, DERMATOL SURG, V37, P835, DOI [10.1111/j.1524-4725.2011.01961.x, 10.1111/j.1524-4725.2011.01961..x]
   Casseres RG, 2020, J AM ACAD DERMATOL, V82, P1524, DOI 10.1016/j.jaad.2020.02.005
   Casseres RG, 2019, J AM ACAD DERMATOL, V81, P265, DOI 10.1016/j.jaad.2018.12.017
   CHAPMAN J, 1972, Journal of the National Medical Association, V64, P328
   Civelek B, 2010, CENT EUR J MED, V5, P674, DOI 10.2478/s11536-009-0126-2
   Consigny PH., 2020, AM ACAD DERMATOL, DOI [10.1016/j.jaad.2020.01.007, DOI 10.1016/J.JAAD.2020.01.007]
   Dahmen RA, 2019, J DTSCH DERMATOL GES, V17, P698, DOI 10.1111/ddg.13875
   Endo Y, 1998, BRIT J DERMATOL, V139, P906
   Falola RA, 2016, PLAST RECONSTR SURG, V138, p219S, DOI 10.1097/PRS.0000000000002671
   Fernandes NC, 2013, AN BRAS DERMATOL, V88, P480, DOI 10.1590/abd1806-4841.20131637
   Giamarellos-Bourboulis EJ, 2021, EXP DERMATOL, V30, P18, DOI 10.1111/exd.14339
   Gonzaga TA, 2013, J BURN CARE RES, V34, P51, DOI 10.1097/BCR.0b013e31826a7be7
   GREELEY PW, 1951, PLAST RECONSTR SURG, V7, P143, DOI 10.1097/00006534-195102000-00007
   Grimstad O, 2019, J EUR ACAD DERMATOL, V33, P1164, DOI 10.1111/jdv.15353
   GROSSER A, 1982, J DERMATOL SURG ONC, V8, P391
   HARRISON BJ, 1987, BMJ-BRIT MED J, V294, P487, DOI 10.1136/bmj.294.6570.487
   Hazen PG, 2010, DERMATOL SURG, V36, P208, DOI 10.1111/j.1524-4725.2009.01427.x
   Hughes LE, 1997, ANN ROY COLL SURG, V79, P309
   Humphries LS, 2016, J PLAST RECONSTR AES, V69, P554, DOI 10.1016/j.bjps.2015.12.004
   Hurley H.J., 1989, Dermatologic surgery, principles and practice
   Ingram JR, 2019, BRIT J DERMATOL, V180, P1009, DOI 10.1111/bjd.17537
   Janse I, 2016, DERMATOL CLIN, V34, P97, DOI 10.1016/j.det.2015.08.007
   Janse IC, 2016, ACTA DERM-VENEREOL, V96, P390, DOI 10.2340/00015555-2258
   Jemec GBE, 2019, BRIT J DERMATOL, V181, P967, DOI 10.1111/bjd.17919
   Jemec GBE, 2012, NEW ENGL J MED, V366, P158, DOI 10.1056/NEJMcp1014163
   Kagan RJ, 2005, SURGERY, V138, P734, DOI 10.1016/j.surg.2005.06.053
   Kerdel FR, 2019, J DRUGS DERMATOL, V18, P170
   Kirschke J, 2015, HAUTARZT, V66, P413, DOI 10.1007/s00105-015-3616-y
   Kovacs M, 2019, J EUR ACAD DERMATOL, V33, pE140, DOI 10.1111/jdv.15368
   Kovács M, 2021, EXP DERMATOL, V30, P82
   Kuo HW, 2003, DERMATOL SURG, V29, P173, DOI 10.1046/j.1524-4725.2003.29044.x
   Mandal A, 2005, SURG-J R COLL SURG E, V3, P23, DOI 10.1016/S1479-666X(05)80006-X
   Marasca C, 2019, BRIT J DERMATOL, V180, P949, DOI 10.1111/bjd.17423
   Martorell A, 2019, DERMATOL SURG, V45, P1237, DOI 10.1097/DSS.0000000000001916
   McPhie ML, 2019, J CUTAN MED SURG, V23, P270, DOI 10.1177/1203475418823529
   Melkun ET, 2005, PLAST RECONSTR SURG, V115, P1385, DOI 10.1097/01.PRS.0000157013.40191.91
   MORGAN WP, 1983, ANN ROY COLL SURG, V65, P235
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mustafa E B, 1980, J Natl Med Assoc, V72, P237
   Oskardmay AN, 2019, J AM ACAD DERMATOL, V81, P702, DOI 10.1016/j.jaad.2019.05.022
   Patel ZS, 2017, CURR PAIN HEADACHE R, V21, DOI 10.1007/s11916-017-0647-3
   Podda M, 2021, EXP DERMATOL, V30, P70
   Provini LE, 2019, PEDIATR DERMATOL, V36, P381, DOI 10.1111/pde.13775
   Prussick L, 2019, BRIT J DERMATOL, V181, P609, DOI 10.1111/bjd.17822
   Rehman N, 2005, BRIT J PLAST SURG, V58, P441, DOI 10.1016/j.bjps.2004.10.022
   Rieger UM, 2009, J PLAST RECONSTR AES, V62, P1355, DOI 10.1016/j.bjps.2008.04.035
   Rockwell WB, 2014, DERMATOL SURG, V40, P116, DOI 10.1111/dsu.12435
   Rompel R, 2000, DERMATOL SURG, V26, P638, DOI 10.1046/j.1524-4725.2000.00043.x
   Sabat R, 2017, HAUTARZT, V68, P994, DOI 10.1007/s00105-017-4079-0
   Savage Kevin T, 2020, Int J Womens Dermatol, V6, P159, DOI 10.1016/j.ijwd.2020.02.007
   Scheinfeld Noah, 2013, Dermatol Online J, V19, P1
   Schneller-Pavelescu L, 2019, J AM ACAD DERMATOL, V80, P1455, DOI 10.1016/j.jaad.2018.12.043
   Scholl L, 2018, HAUTARZT, V69, P149, DOI 10.1007/s00105-017-4114-1
   Soldin MG, 2000, BRIT J PLAST SURG, V53, P434, DOI 10.1054/bjps.1999.3285
   Takiyama H, 2015, INT J SURG CASE REP, V15, P107, DOI 10.1016/j.ijscr.2015.08.028
   van der Zee HH, 2010, J AM ACAD DERMATOL, V63, P475, DOI 10.1016/j.jaad.2009.12.018
   van Hattem S, 2012, DERMATOL SURG, V38, P494, DOI 10.1111/j.1524-4725.2011.02255.x
   van Rappard DC, 2012, BRIT J DERMATOL, V167, P206, DOI 10.1111/j.1365-2133.2012.10807.x
   van Rappard DC, 2012, J EUR ACAD DERMATOL, V26, P898, DOI 10.1111/j.1468-3083.2011.04203.x
   Vossen ARJV, 2019, J AM ACAD DERMATOL, V80, P80, DOI 10.1016/j.jaad.2018.06.046
   WATSON JD, 1985, BRIT J PLAST SURG, V38, P567, DOI 10.1016/0007-1226(85)90022-0
   WILTZ O, 1990, DIS COLON RECTUM, V33, P731, DOI 10.1007/BF02052316
   Wollina U, 2017, INT J DERMATOL, V56, P109, DOI 10.1111/ijd.13393
   Wollina U, 2012, DERMATOL SURG, V38, P110, DOI 10.1111/j.1524-4725.2011.02157.x
   Zouboulis CC, 2019, J EUR ACAD DERMATOL, V33, P19, DOI 10.1111/jdv.15233
   Zouboulis CC, 2015, J EUR ACAD DERMATOL, V29, P619, DOI 10.1111/jdv.12966
   Zouboulis CC, 2019, J AM ACAD DERMATOL, V80, P60, DOI 10.1016/j.jaad.2018.05.040
   Zouboulis CC, 2012, J DTSCH DERMATOL GES, V10, ps1, DOI 10.1111/j.1610-0387.2012.08006.x
NR 89
TC 6
Z9 9
U1 1
U2 3
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0017-8470
EI 1432-1173
J9 HAUTARZT
JI Hautarzt
PD AUG
PY 2021
VL 72
IS 8
SI SI
BP 692
EP 699
DI 10.1007/s00105-021-04864-8
EA JUL 2021
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA TS1UW
UT WOS:000670204000002
PM 34228137
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Sunn, G
AF Sunn, Gabriel
TI Spinal Cord Injury Pressure Ulcer Treatment An Experience-Based Approach
SO PHYSICAL MEDICINE AND REHABILITATION CLINICS OF NORTH AMERICA
LA English
DT Article
DE Pressure ulcer; Pressure ulcer treatment; Spinal cord injury; Wound
   dressing; Wound healing
ID MANAGEMENT; OUTCOMES
AB Pressure ulcers continue to impact the lives of spinal cord injury patients severely. Pressure ulcers must be accurately staged according to National Pressure Ulcer Advisory recommendations before treatment design. The first priority in treatment of pressure ulcers is offloading. Intact skin ulcers may be treated with noncontact nonthermal low-frequency ultrasound. Superficial pressure ulcers may be treated with a combination of collagenase and foam dressings. Deeper pressure ulcers warrant negative-pressure wound therapy dressings along with biologic adjuncts to fill in wound depth. Discovery and treatment of osteomyelitis is a high priority when initially evaluating pressure ulcers. Surgical intervention must always be considered.
C1 [Sunn, Gabriel] Miami VA Hosp, Spinal Cord Injury Unit, Miami, FL 33125 USA.
   [Sunn, Gabriel] Univ Miami, Miller Sch Med, Dept Phys Med & Rehabil, Miami, FL 33101 USA.
C3 University of Miami
RP Sunn, G (通讯作者)，Miami VA Hosp, Spinal Cord Injury Unit, 1C,1201 Northwest 16th St, Miami, FL 33125 USA.
EM gabriel.sunn@gmail.com
CR Chan BC, 2013, INT WOUND J, V10, P431, DOI 10.1111/j.1742-481X.2012.01002.x
   Dorsett P, 2008, SPINAL CORD, V46, P386, DOI 10.1038/sj.sc.3102159
   Ford CN, 2002, ANN PLAS SURG, V49, P55, DOI 10.1097/00000637-200207000-00009
   Fowler E, 2008, OSTOMY WOUND MANAG, V54, P42
   Gélis A, 2009, SPINAL CORD, V47, P651, DOI 10.1038/sc.2009.32
   James GA, 2008, WOUND REPAIR REGEN, V16, P37, DOI 10.1111/j.1524-475X.2007.00321.x
   Kitagawa Tsunemi, 2002, Journal of Nippon Medical School, V69, P268, DOI 10.1272/jnms.69.268
   Pineda Carlos, 2009, Semin Plast Surg, V23, P80, DOI 10.1055/s-0029-1214160
   Scheel-Sailer A, 2013, SPINAL CORD, V51, P828, DOI 10.1038/sc.2013.91
   Shi L, 2009, J WOUND OSTOMY CONT, V36, pS12, DOI 10.1097/WON.0b013e3181bfdd1a
   Srivastava A, 2009, J SPINAL CORD MED, V32, P125, DOI 10.1080/10790268.2009.11760763
NR 11
TC 7
Z9 11
U1 1
U2 33
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1047-9651
EI 1558-1381
J9 PHYS MED REH CLIN N
JI Phys. Med. Rehabil. Clin. N. Am.
PD AUG
PY 2014
VL 25
IS 3
BP 671
EP +
DI 10.1016/j.pmr.2014.05.002
PG 11
WC Rehabilitation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Rehabilitation
GA AN6UU
UT WOS:000340734700012
PM 25064794
DA 2026-07-24
ER

PT J
AU Slade, DAJ
   Carlson, GL
AF Slade, Dominic Alexander James
   Carlson, Gordon Lawrence
TI Takedown of Enterocutaneous Fistula and Complex Abdominal Wall
   Reconstruction
SO SURGICAL CLINICS OF NORTH AMERICA
LA English
DT Article
DE Intestinal failure; Open abdomen; Sepsis; Stoma; Separation of
   components
ID VACUUM-ASSISTED CLOSURE; OPEN ABDOMEN; NUTRITIONAL SUPPORT; INTESTINAL
   FAILURE; STAGED MANAGEMENT; TEMPORARY CLOSURE; FASCIAL CLOSURE; WOUND
   CLOSURE; DEFECTS; REPAIR
AB Key steps in managing patients with enterocutaneous fistulation and an abdominal wall defect include dealing effectively with abdominal sepsis and providing safe and effective nutritional support and skin care, then assessing intestinal and abdominal anatomy, before undertaking reconstructive surgery. The complexity, cost, and morbidity associated with such cases justifies creation of specialized centers in which gastroenterologic, hernia, and plastic surgical expertise, as well as experienced wound and stoma nursing and nutritional and psychological support, can be made available for patients with these challenging problems.
C1 [Slade, Dominic Alexander James; Carlson, Gordon Lawrence] Salford Royal NHS Fdn Trust, Natl Intestinal Failure Ctr, Dept Surg, Salford M6 8HD, Lancs, England.
C3 Salford Royal NHS Foundation Trust
RP Carlson, GL (通讯作者)，Salford Royal NHS Fdn Trust, Natl Intestinal Failure Ctr, Dept Surg, Eccles Old Rd, Salford M6 8HD, Lancs, England.
EM gordon.carlson@srft.nhs.uk
RI Slade, Dominic/AAE-8585-2022
OI Slade, Dominic/0000-0002-6032-8580
CR Adkins AL, 2004, AM SURGEON, V70, P137
   Agwunobi AO, 2001, DIS COLON RECTUM, V44, P1834, DOI 10.1007/BF02234463
   Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Berry SM, 1996, SURG CLIN N AM, V76, P1009, DOI 10.1016/S0039-6109(05)70495-3
   Blatnik J, 2008, AM J SURG, V196, P47, DOI 10.1016/j.amjsurg.2007.06.035
   Bosscha K, 2000, EUR J SURG, V166, P44
   Carlson G, 2010, The Surgical Management of Patients with Intestinal Failure. Issues in Professional Practice
   Carlson GL, 2003, P NUTR SOC, V62, P711, DOI 10.1079/PNS2003287
   Carlson GL, 2010, CURR OPIN CRIT CARE, V16, P347, DOI 10.1097/MCC.0b013e328339fabe
   Connolly PT, 2008, ANN SURG, V247, P440, DOI 10.1097/SLA.0b013e3181612c99
   Depuydt K, 1998, PLAST RECONSTR SURG, V102, P187, DOI 10.1097/00006534-199807000-00031
   Fischer JE, 2009, AM J SURG, V197, P131, DOI 10.1016/j.amjsurg.2008.05.004
   Girvent M, 2000, ANN ROY COLL SURG, V82, P198
   GREENE MA, 1993, SURG GYNECOL OBSTET, V176, P213
   Itani KMF, 2012, SURGERY, V152, P498, DOI 10.1016/j.surg.2012.04.008
   Jamshidi R, 2007, ARCH SURG-CHICAGO, V142, P793, DOI 10.1001/archsurg.142.8.793
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   Johnson Eric K, 2010, Clin Colon Rectal Surg, V23, P195, DOI 10.1055/s-0030-1262988
   Kimata Y, 1999, PLAST RECONSTR SURG, V103, P1191, DOI 10.1097/00006534-199904040-00014
   Lal S, 2006, ALIMENT PHARM THER, V24, P19, DOI 10.1111/j.1365-2036.2006.02941.x
   Lambe G, 2012, BRIT J SURG, V99, P964, DOI 10.1002/bjs.8759
   Lynch AC, 2004, ANN SURG, V240, P825, DOI 10.1097/01.sla.0000143895.17811.e3
   MacLean AA, 2008, ACTA CHIR BELG, V108, P212, DOI 10.1080/00015458.2008.11680206
   Malik RA, 2001, BRIT J SURG, V88, P146, DOI 10.1046/j.1365-2168.2001.01614.x
   Martinez JL, 2008, WORLD J SURG, V32, P436, DOI 10.1007/s00268-007-9304-z
   Maxhimer JB, 2011, ANN PLAS SURG, V66, P285, DOI 10.1097/SAP.0b013e3181e78711
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   MULHOLLAND MW, 1983, SURGERY, V93, P443
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   Ninkovic M, 1998, PLAST RECONSTR SURG, V101, P971, DOI 10.1097/00006534-199804040-00013
   Polk TM, 2012, WORLD J SURG, V36, P524, DOI 10.1007/s00268-011-1315-0
   RAMIREZ OM, 1990, PLAST RECONSTR SURG, V86, P519, DOI 10.1097/00006534-199009000-00023
   Rao M, 2007, COLORECTAL DIS, V9, P266, DOI 10.1111/j.1463-1318.2006.01154.x
   REBER HA, 1978, ANN SURG, V188, P460, DOI 10.1097/00000658-197810000-00003
   Reilingh TSD, 2007, BRIT J SURG, V94, P791, DOI 10.1002/bjs.5817
   SARFEH IJ, 1992, ARCH SURG-CHICAGO, V127, P1027
   SARFEH IJ, 1992, ARCH SURG-CHICAGO, V127, P1030
   Sasaki K, 1998, PLAST RECONSTR SURG, V102, P2244, DOI 10.1097/00006534-199811000-00067
   Schecter WP, 2009, J AM COLL SURGEONS, V209, P484, DOI 10.1016/j.jamcollsurg.2009.05.025
   SCHEIN M, 1990, ARCH SURG-CHICAGO, V125, P1516
   Scott BG, 2005, SCAND J SURG, V94, P9, DOI 10.1177/145749690509400104
   SCRIPCARIU V, 1994, BRIT J SURG, V81, P1475, DOI 10.1002/bjs.1800811024
   Shackley DC, 2000, BJU INT, V86, P624, DOI 10.1046/j.1464-410x.2000.00871.x
   Shetty V, 2006, BRIT J SURG, V93, P1247, DOI 10.1002/bjs.5473
   Stonerock CE, 2003, AM SURGEON, V69, P1030
   Subramonia S, 2009, WORLD J SURG, V33, P931, DOI 10.1007/s00268-009-9947-z
   ten Broek RPG, 2012, ANN SURG, V256, P280, DOI 10.1097/SLA.0b013e31826029a8
   Teubner A, 2004, BJS-BRIT J SURG, V91, P625, DOI 10.1002/bjs.4520
   Trevelyan S L, 2009, J Wound Care, V18, P24
   van der Krabben AA, 2000, BJS-BRIT J SURG, V87, P467, DOI 10.1046/j.1365-2168.2000.01394.x
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   Wangensteen OH, 1934, SURG GYNECOL OBSTET, V59, P766
   Wind J, 2009, AM J SURG, V197, P24, DOI 10.1016/j.amjsurg.2007.11.026
NR 55
TC 23
Z9 28
U1 0
U2 10
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0039-6109
EI 1558-3171
J9 SURG CLIN N AM
JI Surg. Clin.-North Am.
PD OCT
PY 2013
VL 93
IS 5
BP 1163
EP +
DI 10.1016/j.suc.2013.06.006
PG 22
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 237AS
UT WOS:000325841200009
PM 24035080
DA 2026-07-24
ER

PT J
AU Sue, G
   Price, G
   Stahl, R
   Teng, E
   Narayan, D
AF Sue, Gloria
   Price, Gary
   Stahl, Richard
   Teng, Edward
   Narayan, Deepak
TI Major Bleeding in Patients with Mediastinitis: A Heartbreaking Series
SO THORACIC AND CARDIOVASCULAR SURGEON
LA English
DT Article
DE sternum; wound infection; surgery; complications
ID RIGHT-VENTRICULAR RUPTURE; STERNAL WOUND-INFECTION; VACUUM-ASSISTED
   CLOSURE; THERAPY; MANAGEMENT; SURGERY
AB Deep sternal wound infection (DSWI) is a life-threatening complication that develops in 5% of patients undergoing median sternotomy. One feared complication is major bleeding, associated with up to 50% mortality. We characterized a series of patients who experienced major bleeding following DSWI. We included eight patients with DSWI who experienced major bleeding at our institution from 1990 to 2012. The median age was 70.9 (range, 47-81) and the cohort consisted of seven male patients and one female patient. All eight patients required emergent surgical repair for the bleeding and all survived past 30 days postoperatively from the repair.
C1 [Sue, Gloria; Price, Gary; Stahl, Richard; Teng, Edward; Narayan, Deepak] Yale Univ, Sch Med, Dept Surg, New Haven, CT 06520 USA.
C3 Yale University
RP Narayan, D (通讯作者)，Yale Univ, Sch Med, Dept Surg, POB 208062, New Haven, CT 06520 USA.
EM deepak.narayan@yale.edu
CR Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
   Baillot R, 2010, EUR J CARDIO-THORAC, V37, P880, DOI 10.1016/j.ejcts.2009.09.023
   CARTIER R, 1993, J THORAC CARDIOV SUR, V106, P1036, DOI 10.1016/S0022-5223(19)33974-1
   Francel TJ, 2001, ANN THORAC SURG, V72, P1411, DOI 10.1016/S0003-4975(00)02008-7
   Georgiade G, 1998, ANN SURG, V227, P145, DOI 10.1097/00000658-199801000-00021
   Gorlitzer M, 2010, INTERACT CARDIOV TH, V10, P714, DOI 10.1510/icvts.2009.223305
   Ingemansson R, 2013, ANN THORAC SURG, V95, P362, DOI 10.1016/j.athoracsur.2012.08.027
   JULIAN OC, 1957, SURGERY, V42, P753
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Petzina R, 2010, J THORAC CARDIOV SUR, V140, P1133, DOI 10.1016/j.jtcvs.2010.06.063
   Piwnica A, 1988, Eur J Cardiothorac Surg, V2, P172, DOI 10.1016/1010-7940(88)90066-8
   SARR MG, 1984, ANN THORAC SURG, V38, P415, DOI 10.1016/S0003-4975(10)62300-4
   Szerafin T, 1999, ANN THORAC SURG, V68, P1892, DOI 10.1016/S0003-4975(99)01062-0
   van Wingerden JJ, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-121
   Yellin A, 2003, J THORAC CARDIOV SUR, V125, P554, DOI 10.1067/mtc.2003.31
NR 15
TC 1
Z9 1
U1 0
U2 2
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0171-6425
EI 1439-1902
J9 THORAC CARDIOV SURG
JI Thorac. Cardiovasc. Surg.
PD FEB
PY 2015
VL 63
IS 1
BP 73
EP 76
DI 10.1055/s-0034-1376402
PG 4
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA AZ0RX
UT WOS:000347953300012
PM 24875809
DA 2026-07-24
ER

PT J
AU Richmond, NA
   Maderal, AD
   Vivas, AC
AF Richmond, Nicholas A.
   Maderal, Andrea D.
   Vivas, Alejandra C.
TI Evidence-based management of common chronic lower extremity ulcers
SO DERMATOLOGIC THERAPY
LA English
DT Article
DE diabetic foot ulcer; lower extremity wounds; venous leg ulcer
ID CHRONIC VENOUS INSUFFICIENCY; COLONY-STIMULATING FACTOR; DIABETIC FOOT
   ULCERS; VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; RANDOMIZED
   CONTROLLED-TRIAL; CHRONIC LEG ULCERS; TOTAL-CONTACT CAST; MATRIX
   METALLOPROTEINASES; COMPRESSION THERAPY
AB Chronic lower extremity ulcers are a significant burden on patients and health care systems worldwide. Although relatively common, these wounds can be difficult to treat and present a challenge to physicians. Treatment has often been based on anecdotal accounts; however, there is a growing emphasis on using evidence-based conclusions to guide clinical decisions. In this review article, the standard of care and adjuvant therapies of venous leg ulcers and diabetic foot ulcers are presented from an evidence-based perspective.
C1 [Richmond, Nicholas A.; Maderal, Andrea D.; Vivas, Alejandra C.] Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA.
C3 University of Miami
RP Richmond, NA (通讯作者)，Univ Miami, Miller Sch Med, Dept Dermatol, Wound Res Clin, 1321 NW 14th St,West Bldg,Room 504, Miami, FL 33136 USA.
EM nrichmond@med.miami.edu
CR Abbade LPF, 2005, INT J DERMATOL, V44, P449, DOI 10.1111/j.1365-4632.2004.02456.x
   ABUOWN A, 1994, J VASC SURG, V20, P705, DOI 10.1016/S0741-5214(94)70157-1
   Ali R, 2008, JCPSP-J COLL PHYSICI, V18, P695, DOI 11.2008/JCPSP.694698
   ALLENBY F, 1973, LANCET, V2, P1412
   American Diabetes Association, 1999, Diabetes Care, V22, P1354
   [Anonymous], COCHRANE DATABASE SY
   [Anonymous], AM COLL FOOT ANKL SU
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Armstrong DG, 2002, J AM PODIAT MED ASSN, V92, P405, DOI 10.7547/87507315-92-7-405
   Beidler SK, 2008, WOUND REPAIR REGEN, V16, P642, DOI 10.1111/j.1524-475X.2008.00415.x
   Mompo JIB, 2011, REV ESP QUIM, V24, P233
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Boulton AJM, 2005, LANCET, V366, P1719, DOI 10.1016/S0140-6736(05)67698-2
   Brem H, 2004, AM J SURG, V187, p1S, DOI 10.1016/S0002-9610(03)00299-X
   Brown-Etris M, 2002, WOUNDS, V14, P150
   Bus SA, 2008, DIABETES-METAB RES, V24, pS162, DOI 10.1002/dmrr.850
   Cardinal M, 2009, WOUND REPAIR REGEN, V17, P306, DOI 10.1111/j.1524-475X.2009.00485.x
   Charles H., 1991, Journal of District Nursing, V4, P4
   Cianfarani F, 2006, BRIT J DERMATOL, V154, P34, DOI 10.1111/j.1365-2133.2005.06925.x
   Cruciani M, 2009, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006810.pub2
   CULLUM NA, 2010, COCHRANE DATABASE SY
   da Costa RM, 1999, WOUND REPAIR REGEN, V7, P17, DOI 10.1046/j.1524-475X.1999.00017.x
   Demling RH, 2004, WOUNDS, V16, P18
   DUMVILLE JC, 2012, COCHRANE DATABASE SY
   Dumville JC, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003091.pub2
   Edwards H, 2009, J CLIN NURS, V18, P1541, DOI 10.1111/j.1365-2702.2008.02648.x
   Edwards JS, 2010, KNOWL MAN RES PRACT, V8, P1, DOI 10.1057/kmrp.2009.39
   Falanga V, 1998, ARCH DERMATOL, V134, P293, DOI 10.1001/archderm.134.3.293
   Finlayson K, 2009, INT J NURS STUD, V46, P1071, DOI 10.1016/j.ijnurstu.2008.12.012
   Frykberg RG, 2010, J VASC SURG, V52, p44S, DOI 10.1016/j.jvs.2010.06.008
   Gough A, 1997, LANCET, V350, P855, DOI 10.1016/S0140-6736(97)04495-4
   Heinen M, 2012, INT J NURS STUD, V49, P151, DOI 10.1016/j.ijnurstu.2011.09.005
   HUNT JA, 1992, DIABETIC MED, V9, P749
   Jaschke E, 1999, INT J DERMATOL, V38, P380, DOI 10.1046/j.1365-4362.1999.00665.x
   JULL A, 2002, COCHRANE DATABASE SY
   Kan YM, 2001, ARCH SURG-CHICAGO, V136, P1364, DOI 10.1001/archsurg.136.12.1364
   Kessler CM, 1996, BLOOD COAGUL FIBRIN, V7, P437, DOI 10.1097/00001721-199606000-00002
   LAYTON AM, 1994, LANCET, V344, P164, DOI 10.1016/S0140-6736(94)92759-6
   Löndahl M, 2011, CURR DIABETES REP, V11, P285, DOI 10.1007/s11892-011-0194-y
   Löndahl M, 2010, DIABETES CARE, V33, P998, DOI 10.2337/dc09-1754
   Lown I, 2005, WOUNDS, V17, P27
   Margolis DJ, 1999, DIABETES CARE, V22, P692, DOI 10.2337/diacare.22.5.692
   Margolis DJ, 1999, ARCH DERMATOL, V135, P920, DOI 10.1001/archderm.135.8.920
   Margolis DJ, 2002, J AM ACAD DERMATOL, V46, P381, DOI 10.1067/mjd.2002.121739
   Marston WA, 2004, EXPERT REV MED DEVIC, V1, P21, DOI 10.1586/17434440.1.1.21
   Marston WA, 2003, DIABETES CARE, V26, P1701, DOI 10.2337/diacare.26.6.1701
   Meyer FJ, 2003, BRIT J SURG, V90, P934, DOI 10.1002/bjs.4173
   Moffatt C, 2009, INT WOUND J, V6, P386, DOI 10.1111/j.1742-481X.2009.00634.x
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mostow EN, 2005, J VASC SURG, V41, P837, DOI 10.1016/j.jvs.2005.01.042
   Nelson EA, 2008, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001899.pub2
   Nelson EA, 2006, DIABETIC MED, V23, P348, DOI 10.1111/j.1464-5491.2006.01785.x
   Neumann HAM, 1996, VASA-J VASCULAR DIS, V25, P127
   Nikolovska S, 2005, MED SCI MONITOR, V11, pCR337
   Norgauer J, 2002, BRIT J DERMATOL, V147, P1180, DOI 10.1046/j.1365-2133.2002.05025.x
   O'Brien JF, 2003, BRIT J SURG, V90, P794, DOI 10.1002/bjs.4167
   O'Meara S., 2009, BMJ-BRIT MED J, V338, P1054
   O'Meara S, 2009, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD000265.pub3
   OMeara S., 2010, COCHRANE DB SYST REV, pCD003557, DOI [10.1002/14651858.CD003557.pub3, DOI 10.1002/14651858.CD003557.PUB3]
   Padberg FT Jr, 2004, J VASC SURG, V39, P79, DOI 10.1016/j.jvs.2003.09.036
   Peters EJG, 2012, DIABETES-METAB RES, V28, P142, DOI 10.1002/dmrr.2247
   Polignano R, 2004, J Wound Care, V13, P21
   Rathur HM, 2005, HORM METAB RES, V37, pS61, DOI 10.1055/s-2005-861398
   Roaldsen KS, 2006, PHYSIOTHER RES INT, V11, P191, DOI 10.1002/pri.337
   ROSS R, 1989, LANCET, V1, P1179
   RUBIN JR, 1990, ARCH SURG-CHICAGO, V125, P489
   SAMLASKA CP, 1994, J AM ACAD DERMATOL, V30, P603, DOI 10.1016/S0190-9622(94)70069-9
   Sheehan P, 2003, DIABETES CARE, V26, P1879, DOI 10.2337/diacare.26.6.1879
   Simka M, 2007, J DERMATOL, V34, P537, DOI 10.1111/j.1346-8138.2007.00327.x
   Snyder Robert J, 2010, Ostomy Wound Manage, V56, pS1
   Steed DL, 2006, WOUND REPAIR REGEN, V14, P680, DOI 10.1111/j.1524-475X.2006.00176.x
   Steed DL, 1996, J AM COLL SURGEONS, V183, P61
   STEMMER R, 1980, HAUTARZT, V31, P355
   Taylor AD, 1998, PHLEBOLOGY, V13, P20, DOI 10.1177/026835559801300105
   Valencia IC, 2001, J AM ACAD DERMATOL, V44, P401, DOI 10.1067/mjd.2001.111633
   Veves A, 2001, DIABETES CARE, V24, P290, DOI 10.2337/diacare.24.2.290
   Vig S, 2011, J TISSUE VIABILITY, V20, pS1, DOI 10.1016/j.jtv.2011.07.002
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Watson JM, 2011, BMJ-BRIT MED J, V342, DOI 10.1136/bmj.d1092
   Wieman TJ, 1998, DIABETES CARE, V21, P822, DOI 10.2337/diacare.21.5.822
   Williams D, 2005, WOUND REPAIR REGEN, V13, P131, DOI 10.1111/j.1067-1927.2005.130203.x
NR 81
TC 119
Z9 140
U1 0
U2 34
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1396-0296
EI 1529-8019
J9 DERMATOL THER
JI Dermatol. Ther.
PD MAY-JUN
PY 2013
VL 26
IS 3
SI SI
BP 187
EP 196
DI 10.1111/dth.12051
PG 10
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 159GV
UT WOS:000320034800002
PM 23742279
DA 2026-07-24
ER

PT J
AU Greer, SE
   Longaker, MT
   Margiotta, M
   Mathews, AJ
   Kasabian, A
AF Greer, SE
   Longaker, MT
   Margiotta, M
   Mathews, AJ
   Kasabian, A
TI The use of subatmospheric pressure dressing for the coverage of radial
   forearm free flap donor-site exposed tendon complications
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article; Proceedings Paper
CT Meeting of the International-Society-of-Plastic-Reconstructive-Surgeons
CY JUN   22, 1999
CL LOS ANGELES, CALIFORNIA
SP Int Soc Plast Reconstruct Surgeons
AB Since its description in China in 1978, the radial forearm free flap has become a workhorse for the reconstructive surgeon. However, the flap has known disadvantages in complications of the wrist donor site. Skin graft breakdown with exposure of the flexor tendons of the wrist is the most common. The authors describe in a patient series a new treatment for this complication. They used subatmospheric pressure dressing to stimulate granulation tissue coverage of the tendon and to facilitate epithelialization. As many as one third of all patients undergoing radial forearm free flaps develop exposed tendon complications and may benefit from Vacuum Assisted Closure (VAC) therapy.
C1 NYU, Med Ctr, Inst Reconstruct Plast Surg, New York, NY 10016 USA.
C3 New York University
RP Greer, SE (通讯作者)，300 E 34th St,Apartment 9F, New York, NY 10016 USA.
OI Longaker, Michael/0000-0003-1430-8914
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BARDSLEY AF, 1990, PLAST RECONSTR SURG, V86, P287, DOI 10.1097/00006534-199008000-00014
   EVANS GRD, 1994, AM J SURG, V168, P446, DOI 10.1016/S0002-9610(05)80096-0
   Lutz BS, 1999, PLAST RECONSTR SURG, V103, P132, DOI 10.1097/00006534-199901000-00021
   SONG RY, 1982, CLIN PLAST SURG, V9, P21
   SWANSON E, 1990, PLAST RECONSTR SURG, V85, P258, DOI 10.1097/00006534-199002000-00016
NR 6
TC 25
Z9 36
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-7043
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD NOV
PY 1999
VL 43
IS 5
BP 551
EP 554
DI 10.1097/00000637-199911000-00016
PG 4
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 253LD
UT WOS:000083557300018
PM 10560875
DA 2026-07-24
ER

PT J
AU Bashir, MM
   Sohail, M
   Shami, HB
AF Bashir, Muhammad Mustehsan
   Sohail, Muhammad
   Shami, Hussan Birkhez
TI Traumatic Wounds of the Upper Extremity Coverage Strategies
SO HAND CLINICS
LA English
DT Article
DE Soft tissue coverage; Upper limb reconstruction; Flap; Trauma
ID VACUUM ASSISTED CLOSURE; SOFT-TISSUE COVERAGE; ADVANCEMENT FLAP; HAND;
   RECONSTRUCTION; INJURIES
AB Soft tissue coverage of traumatic wounds of the upper extremity is often required to restore adequate function and form. An optimal coverage should be stable, durable, and able to withstand heavy demands of work, should allow free joint mobility, and. should have an aesthetically acceptable appearance. Reconstructive options for coverage include autologous tissue and dermal skin substitutes. Multiple factors, including wound characteristics and complexity, general condition of the patient, and surgeon comfort and expertise, help in the selection of the reconstructive technique. This article summarizes commonly used soft tissue reconstructive options for traumatic wounds of the upper extremity.
C1 [Bashir, Muhammad Mustehsan; Shami, Hussan Birkhez] King Edward Med Univ, Mayo Hosp, Dept Plast, Reconstruct Surg & Burn Unit, House 327 Block H DHA,Phase 5, Lahore, Pakistan.
   [Sohail, Muhammad] King Edward Med Univ, Mayo Hosp, Dept Plast, Reconstruct Surg & Burn Unit, 86A Habibullah Rd, Lahore, Pakistan.
RP Sohail, M (通讯作者)，King Edward Med Univ, Mayo Hosp, Dept Plast, Reconstruct Surg & Burn Unit, 86A Habibullah Rd, Lahore, Pakistan.
EM drsohail72@gmail.com
OI Sohail, Muhammad/0000-0003-0772-7723
CR Abdelkader R, 2016, Surgical Science, V07, P309, DOI 10.4236/ss.2016.77044
   Adani R, 2015, BMC Proceedings, V9, DOI 10.1186/1753-6561-9-s3-a60
   Ali A, 2007, EGYPT J PLAST RECONS, V31, P181
   Alphonsus Chong Ks, 2011, Indian J Plast Surg, V44, P219, DOI 10.4103/0970-0358.85343
   Antohi N, 2005, TMJ, V55, P27
   ATASOY E, 1970, J BONE JOINT SURG AM, VA 52, P921, DOI 10.2106/00004623-197052050-00006
   Becker C., 1988, Eur J Plast Surg, V11, P79, DOI [10.1007/BF00299217, DOI 10.1007/BF00299217]
   Biswas D, 2014, J HAND SURG-AM, V39, P992, DOI 10.1016/j.jhsa.2013.09.027
   Cavadas PC, 2008, PLAST RECONSTR SURG, V122, P1823, DOI 10.1097/PRS.0b013e31818cc222
   Cheema T, 2014, COMPLEX INJURIES HAN, P51
   Eberlin KR, 2014, PLAST RECONSTR SURG, V133, P91, DOI 10.1097/01.prs.0000436831.73323.88
   Ellis CV, 2012, PLAST RECONSTR SURG, V130, p256S, DOI 10.1097/PRS.0b013e318265a5cf
   Goertz O, 2012, J HAND SURG-AM, V37A, P2088, DOI 10.1016/j.jhsa.2012.07.014
   Griffin Michelle, 2014, Open Orthop J, V8, P409, DOI 10.2174/1874325001408010409
   Grobbelaar AO, 1997, J HAND SURG-BRIT EUR, V22B, P204, DOI 10.1016/S0266-7681(97)80064-2
   Hansen SL, 2014, GRAB SMITHS PLASTIC, P737
   Harrison BL, 2013, PLAST RECONSTR SURG, V132, P591, DOI 10.1097/PRS.0b013e31829ad012
   Hashmi Pervaiz Mehmood, 2004, J Coll Physicians Surg Pak, V14, P485
   Horta R, 2011, J HAND MICROSURG, V3, P73, DOI 10.1007/s12593-011-0046-7
   Hsu CC, 2009, PLAST RECONSTR SURG, V123, P1739, DOI 10.1097/PRS.0b013e3181a65b00
   Ignatiadis IA, 2008, EEXOT, V59, P101
   Jokuszies A, 2010, OPER ORTHOP TRAUMATO, V22, P440, DOI 10.1007/s00064-010-9017-6
   Jones NF, 2008, PLAST RECONSTR SURG, V121, P887, DOI 10.1097/01.prs.0000299924.69019.57
   Kneser U, 2006, ZBL CHIR, V131, pS7, DOI 10.1055/s-2006-921470
   Koch H, 2005, BRIT J PLAST SURG, V58, P1131, DOI 10.1016/j.bjps.2005.04.047
   Kruavit A, 2004, THAI J SURG, V25, P7
   KUTLER W, 1947, JAMA-J AM MED ASSOC, V133, P29, DOI 10.1001/jama.1947.62880010007007
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   Langer V, 2014, SCI WORLD J, DOI 10.1155/2014/640430
   Latifi Rifat, 2014, J Emerg Trauma Shock, V7, P228, DOI 10.4103/0974-2700.136870
   MACHT SD, 1980, J HAND SURG-AM, V5, P372, DOI 10.1016/S0363-5023(80)80179-1
   Makkar RM, 2012, EGYPT J PLAST RECONS, V36, P147
   Momeni A, 2008, INJURY, V39, P1460, DOI 10.1016/j.injury.2008.02.015
   Ng ZY, 2015, SEMIN PLAST SURG, V29, P48, DOI 10.1055/s-0035-1544170
   Prabhu M., 2013, Int J Pharm Med Bio Sc, V2, P8
   Rajappa S, 2017, International Journal of Research in Orthopaedics, V3, P164, DOI 10.18203/issn.2455-4510.intjresorthop20170009
   Sungur Nezih, 2012, Hand (N Y), V7, P79, DOI 10.1007/s11552-011-9389-6
   Thoma A, 2010, CAN J PLAST SURG, V18, pE47, DOI 10.1177/229255031001800407
   Thorne CH, GRAB SMITHS PLASTIC
   Wiedrich TA, 2001, J AM SOC SURG HAND, V1, P25, DOI DOI 10.1053/JSSH.2001.21783
   Yilderim A R., 2016, CUMHURIYET MED J, V38, P332
NR 41
TC 21
Z9 26
U1 0
U2 3
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0749-0712
EI 1558-1969
J9 HAND CLIN
JI Hand Clin.
PD FEB
PY 2018
VL 34
IS 1
BP 61
EP +
DI 10.1016/j.hcl.2017.09.007
PG 16
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA FR0DH
UT WOS:000418730800009
PM 29169598
DA 2026-07-24
ER

PT J
AU Munakata, H
   Murakami, Y
   Mabuni, K
   Tsuchiya, H
   Shinzato, M
   Umemura, T
   Kugai, T
AF Munakata, Hiroshi
   Murakami, Yu
   Mabuni, Katsuhito
   Tsuchiya, Hiroyuki
   Shinzato, Moriaki
   Umemura, Takehiro
   Kugai, Tadao
TI Successful surgical treatment of traumatic sternal fracture with
   extensive mediastinal abscess and concomitant mitral valve endocarditis:
   a case report
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
DE Traumatic sternal fracture; Mediastinitis; Endocarditis; Aggressive
   debridement; Successfully staged strategy
ID OSTEOMYELITIS; SURGERY
AB Background: A traumatic sternal fracture with extensive mediastinal abscess and concomitant native valve endocarditis is an extremely rare but catastrophic situation.
   Case presentation: For 2 weeks, the co-infected patient was treated with aggressive debridement for the mediastinitis, change of vacuum-assisted closure therapy dressings, vegetectomy and valve repair through lower partial sternotomy, and delayed primary wound closure.
   Conclusions: To the best of our knowledge, this successful staged strategy has not been previously reported. We believe that our quick decision about repeated surgical interventions and preservation of the manubrium led to a favorable result.
C1 [Munakata, Hiroshi; Murakami, Yu; Mabuni, Katsuhito; Kugai, Tadao] Okinawa Prefectural Nambu Med Ctr, Dept Cardiovasc Surg, Haebaru, Japan.
   [Munakata, Hiroshi; Murakami, Yu; Mabuni, Katsuhito; Tsuchiya, Hiroyuki; Shinzato, Moriaki; Umemura, Takehiro; Kugai, Tadao] Childrens Med Ctr, Haebaru, Japan.
   [Tsuchiya, Hiroyuki; Shinzato, Moriaki; Umemura, Takehiro] Okinawa Prefectural Nambu Med Ctr, Dept Emergency & Crit Care Med, Haebaru, Japan.
RP Munakata, H (通讯作者)，Okinawa Prefectural Nambu Med Ctr, Dept Cardiovasc Surg, Haebaru, Japan.; Munakata, H (通讯作者)，Childrens Med Ctr, Haebaru, Japan.
EM h-munakata@k7.dion.ne.jp
CR Ann JY, 2013, INTERNAL MED, V52, P511, DOI 10.2169/internalmedicine.52.8958
   Athanassiadi Kalliopi A, 2009, Thorac Surg Clin, V19, P37, DOI 10.1016/j.thorsurg.2008.09.012
   Chiang IH, 2015, ANN THORAC SURG, V100, P1907, DOI 10.1016/j.athoracsur.2015.01.078
   Cuschieri J, 1999, J TRAUMA, V47, P551, DOI 10.1097/00005373-199909000-00022
   Ennker IC, 2012, HEART LUNG VESSEL, V4, P233
   Gib MC, 2013, REV BRAS CIR CARDIOV, V28, P200, DOI 10.5935/1678-9741.20130029
   Kaneda T, 2011, ANN THORAC CARDIOVAS, V17, P528, DOI 10.5761/atcs.cr.10.01622
   Kang DH, 2012, NEW ENGL J MED, V366, P2466, DOI 10.1056/NEJMoa1112843
   Mallinson RH, 1999, J ROY SOC MED, V92, P87, DOI 10.1177/014107689909200213
   Patel NNB, 2008, ANN THORAC SURG, V86, P1997, DOI 10.1016/j.athoracsur.2008.03.054
   Risnes I, 2010, ANN THORAC SURG, V89, P1502, DOI 10.1016/j.athoracsur.2010.02.038
   Urbanski PP, 2009, ANN THORAC SURG, V88, P987, DOI 10.1016/j.athoracsur.2009.01.037
   Velissaris Theodore, 2002, Eur J Cardiothorac Surg, V22, P439, DOI 10.1016/S1010-7940(02)00335-4
NR 13
TC 1
Z9 1
U1 0
U2 2
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD AUG 15
PY 2016
VL 11
AR 134
DI 10.1186/s13019-016-0507-y
PG 4
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA DT7QU
UT WOS:000381682100001
PM 27528381
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Steinsträsser, L
   Hasler, R
   Hirsch, T
   Daigeler, A
   Langer, S
   Steinau, HU
AF Steinstraesser, L.
   Hasler, R.
   Hirsch, T.
   Daigeler, A.
   Langer, S.
   Steinau, H. U.
TI Future treatment options for chronic wounds
SO CHIRURG
LA German
DT Article
DE wound therapy; wound healing; chronic wound; wound management; skin
   substitutes
ID VACUUM-ASSISTED CLOSURE; HYPERBARIC-OXYGEN; ANTIMICROBIAL PEPTIDES;
   THERAPY; DEFENSE; SKIN; DEBRIDEMENT
AB The skin plays an important role in the human immune system, working as a barrier to pathologic influences. A chronic wound breaks that barrier and eliminates that function. Affected patients can suffer from significant reductions in quality of life and become socially isolated. The inability to work may have serious economic consequences for the individual and the community. Treating these wounds with novel, evidence-based techniques can accelerate wound healing while reducing the length of in- and outpatient treatment and thereby the overall costs. This article discusses current and future treatment options in wound conditioning, therapy, and regeneration.
C1 [Steinstraesser, L.; Hasler, R.; Hirsch, T.; Daigeler, A.; Langer, S.; Steinau, H. U.] Ruhr Univ Bochum, BG Univ Klinikum Bergmannsheil, Klin Plast Chirurg & Schwerbrandverletzte, D-44789 Bochum, Germany.
C3 Ruhr University Bochum
RP Steinsträsser, L (通讯作者)，Ruhr Univ Bochum, BG Univ Klinikum Bergmannsheil, Klin Plast Chirurg & Schwerbrandverletzte, Burkle Camp Pl 1, D-44789 Bochum, Germany.
EM lars.steinstraesser@ruhr-uni-bochum.de
RI Hirsch, Tobias/AAS-6707-2021; Daigeler, Aien/C-9417-2016
OI Daigeler, Aien/0000-0002-0012-9870
CR Al Kurdi D, 2008, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001180.pub2
   [Anonymous], 2007, COCHRANE DB SYST REV
   [Anonymous], COCHRANE DATABASE SY
   BARBUL A, 2006, WOUND REPAIR REGEN, V14, P102
   Berendt AR, 2006, CLIN INFECT DIS, V43, P193, DOI 10.1086/505223
   Bowling FL, 2007, DIABETES CARE, V30, P370, DOI 10.2337/dc06-2348
   CHANG N, 1983, ANN SURG, V197, P470, DOI 10.1097/00000658-198304000-00017
   Clare MP, 2002, FOOT ANKLE INT, V23, P896, DOI 10.1177/107110070202301002
   Cronjé FJ, 2005, SAMJ S AFR MED J, V95, P840
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Fonder MA, 2008, J AM ACAD DERMATOL, V58, P185, DOI 10.1016/j.jaad.2007.08.048
   Ganz T, 2003, NAT REV IMMUNOL, V3, P710, DOI 10.1038/nri1180
   Gerry R, 2007, ANN PLAS SURG, V59, P58, DOI 10.1097/01.sap.0000263420.70303.cc
   Gwan-Nulla DN, 2001, ANN PLAS SURG, V47, P552, DOI 10.1097/00000637-200111000-00014
   Hancock REW, 1997, LANCET, V349, P418, DOI 10.1016/S0140-6736(97)80051-7
   Heilborn JD, 2003, J INVEST DERMATOL, V120, P379, DOI 10.1046/j.1523-1747.2003.12069.x
   Hess CL, 2003, ANN PLAS SURG, V51, P210, DOI 10.1097/01.SAP.0000058513.10033.6B
   Hirsch T, 2008, PROTEIN PEPTIDE LETT, V15, P238
   Hunt TK, 1997, SURG CLIN N AM, V77, P587, DOI 10.1016/S0039-6109(05)70570-3
   Jacobsen F, 2005, GENE THER, V12, P1494, DOI 10.1038/sj.gt.3302568
   KANAVEL AB, 1914, INFECTIONS HAND
   KISTLER D, 1989, Versicherungsmedizin, V41, P116
   Konig M, 2005, J Wound Care, V14, P320
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mustoe TA, 2006, PLAST RECONSTR SURG, V117, p35S, DOI 10.1097/01.prs.0000225431.63010.1b
   Rennekampff HO, 2006, BURNS, V32, P64, DOI 10.1016/j.burns.2005.07.010
   ROBSON MC, 1990, CLIN PLAST SURG, V17, P485
   Robson MC, 2000, ARCH SURG-CHICAGO, V135, P773, DOI 10.1001/archsurg.135.7.773
   Steed DL, 2006, WOUND REPAIR REGEN, V14, P680, DOI 10.1111/j.1524-475X.2006.00176.x
   Steed DL, 2006, PLAST RECONSTR SURG, V117, p143S, DOI 10.1097/01.prs.0000222526.21512.4c
   STEED DL, 1995, J VASC SURG, V21, P71, DOI 10.1016/S0741-5214(95)70245-8
   Steinstraesser L, 2006, ANN PLAS SURG, V56, P93, DOI 10.1097/01.sap.0000190883.30005.91
   STODDARD SR, 1995, J AM PODIAT MED ASSN, V85, P218, DOI 10.7547/87507315-85-4-218
   Tantawi T I, 2007, J Wound Care, V16, P379
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   VOGT PM, 1995, ANN PLAS SURG, V34, P493, DOI 10.1097/00000637-199505000-00007
   Wollina U, 2000, J EUR ACAD DERMATOL, V14, P285, DOI 10.1046/j.1468-3083.2000.00105.x
   Yang D, 2004, ANNU REV IMMUNOL, V22, P181, DOI 10.1146/annurev.immunol.22.012703.104603
   ZASLOFF M, 1987, P NATL ACAD SCI USA, V84, P5449, DOI 10.1073/pnas.84.15.5449
NR 40
TC 6
Z9 6
U1 0
U2 9
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0009-4722
EI 1433-0385
J9 CHIRURG
JI Chirurg
PD JUN
PY 2008
VL 79
IS 6
BP 555
EP 559
DI 10.1007/s00104-008-1504-z
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 312WF
UT WOS:000256702400006
PM 18458798
DA 2026-07-24
ER

PT J
AU Giacalone, PL
   El Gareh, N
   Rihaoui, S
   Giovannini, U
AF Giacalone, Pierre-Ludovic
   El Gareh, Nouredine
   Rihaoui, Samia
   Giovannini, Uberto
TI Transverse rectus abdominis myocutaneous flap wound-healing
   complications in breast reconstruction: Assisted closure using foam
   suction dressing
SO BREAST JOURNAL
LA English
DT Article
DE foam suction dressing; TRAM flap; wound complication
ID NEGATIVE-PRESSURE; EXPERIENCE; THERAPY; PROMOTE; TRIAL
AB Transverse rectus abdominis myocutaneous (TRAM) flap necrosis is a difficult reconstructive problem which historically has entailed protracted management with poor aesthetic outcome. The use of a foam suction dressing achieves effective delayed primary closure of the flap wound with an acceptable aesthetic result. The results of using a vacuum-assisted closure (VAC) system were examined in three patients. The VAC system was found to be safe and effective in facilitating the closure of large and complex wounds without skin grafting. This option should thus be given serious consideration in some difficult wound healing situations.
C1 Hop Arnaud de Villeneuve, Dept Obstet & Gynecol, F-34295 Montpellier 5, France.
   Hop Lapeyronie, Burn Unit, Montpellier, France.
C3 Universite de Montpellier; CHU de Montpellier; Universite de
   Montpellier; CHU de Montpellier
RP Giacalone, PL (通讯作者)，Hop Arnaud de Villeneuve, Dept Obstet & Gynecol, 371 Rue Doyen Gaston Giraud, F-34295 Montpellier 5, France.
EM pl-giacalone@chu-montpellier.fr
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Banwell P, 1998, BRIT J PLAST SURG, V51, P79, DOI 10.1016/S0007-1226(98)80142-2
   Clare MP, 2002, FOOT ANKLE INT, V23, P896, DOI 10.1177/107110070202301002
   Fenn CH, 2001, BRIT J PLAST SURG, V54, P348, DOI 10.1054/bjps.2000.3552
   Fleischmann W, 1995, Eur J Orthop Surg Traumatol, V5, P37, DOI 10.1007/BF02716212
   Fuchs U, 2005, ANN THORAC SURG, V79, P526, DOI 10.1016/j.athoracsur.2004.08.032
   Joseph E, 2000, WOUNDS, V12, P60
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   MCCALLON S.K., 2000, Ostomy Wound Manage, V46, P28
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
NR 12
TC 5
Z9 5
U1 0
U2 1
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 1075-122X
J9 BREAST J
JI Breast J.
PD SEP-OCT
PY 2006
VL 12
IS 5
BP 481
EP 484
DI 10.1111/j.1075-122X.2006.00306.x
PG 4
WC Oncology; Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Obstetrics & Gynecology
GA 079TO
UT WOS:000240201000015
PM 16958970
DA 2026-07-24
ER

PT J
AU Scholl, L
   Hessam, S
   Reitenbach, S
   Bechara, FG
AF Scholl, L.
   Hessam, S.
   Reitenbach, S.
   Bechara, F. G.
TI Surgical treatment options for hidradenitis suppurativa/acne inversa
SO HAUTARZT
LA German
DT Article
DE Excision; Recurrence rate; Resection; Reconstruction; Aftercare
ID NEGATIVE-PRESSURE DRESSINGS; TISSUE-SPARING EXCISION; VACUUM-ASSISTED
   CLOSURE; DIOXIDE LASER EXCISION; AXILLARY HIDRADENITIS; PATIENT
   SATISFACTION; WIDE EXCISION; ACNE INVERSA; MANAGEMENT; SURGERY
AB Hidradenitis suppurativa/acne inversa (HS/AI) is a chronic inflammatory skin disease. Therapy consists of conservative and surgical treatment options. In Hurley stages II and III, surgical intervention is regarded as the method of choice for areas with irreversible tissue destruction. Resection techniques with different grades of invasiveness are described in the literature. Nevertheless, there is no generally accepted concept regarding resection and reconstruction techniques or specific postoperative care. Due to lack of definitions of recurrence after surgery and poor study quality, recurrence rates are difficult to determine.
C1 [Scholl, L.; Hessam, S.; Reitenbach, S.; Bechara, F. G.] Klin Ruhr Univ Bochum, St Josef Hosp, Klin Dermatol Venerol & Allergol, Gudrunstr 56, D-44791 Bochum, Germany.
C3 Ruhr University Bochum
RP Bechara, FG (通讯作者)，Klin Ruhr Univ Bochum, St Josef Hosp, Klin Dermatol Venerol & Allergol, Gudrunstr 56, D-44791 Bochum, Germany.
EM f.bechara@klinikum-bochum.de
OI Hessam, Schapoor/0000-0001-6547-6577
CR Aksakal AB, 2008, DERMATOL SURG, V34, P228, DOI 10.1111/j.1524-4725.2007.34042.x
   Alharbi Z, 2012, BMC DERMATOL, V12, DOI 10.1186/1471-5945-12-9
   Altmann S, 2001, CHIRURG, V72, P1413, DOI 10.1007/s001040170004
   Andersen RK, 2017, CLIN DERMATOL, V35, P218, DOI 10.1016/j.clindermatol.2016.10.018
   ANDERSON BB, 1982, J NATL MED ASSOC, V74, P999
   ANDERSON M J Jr, 1958, Dis Colon Rectum, V1, P23, DOI 10.1007/BF02616510
   ARIYAN S, 1976, PLAST RECONSTR SURG, V58, P44, DOI 10.1097/00006534-197607000-00007
   Ather Shahzad, 2006, Int Wound J, V3, P159, DOI 10.1111/j.1742-481X.2006.00235.x
   Balik E, 2009, WORLD J SURG, V33, P481, DOI 10.1007/s00268-008-9845-9
   BANERJEE AK, 1992, BRIT J SURG, V79, P863, DOI 10.1002/bjs.1800790905
   Bechara FG, 2016, EXP DERMATOL, V25, P8
   Bechara Falk G, 2016, MMW Fortschr Med, V158, P52, DOI [10.1007/s15006-016-8662-6, 10.1007/s15006-016-8662-6]
   BELL BA, 1978, J ROY SOC MED, V71, P511, DOI 10.1177/014107687807100710
   Bieniek A, 2010, DERMATOL SURG, V36, P1998, DOI 10.1111/j.1524-4725.2010.01763.x
   Bilali Sokol, 2012, Acta Chir Iugosl, V59, P91
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Blok JL, 2015, J EUR ACAD DERMATOL, V29, P379, DOI 10.1111/jdv.12376
   Bocchini SF, 2003, DIS COLON RECTUM, V46, P944, DOI 10.1007/s10350-004-6691-1
   Bohn J, 2001, SCAND J PLAST RECONS, V35, P305
   Breuninger H, 2004, HAUTARZT, V55, P254, DOI 10.1007/s00105-004-0698-3
   BROADWATER JR, 1982, AM J SURG, V144, P668, DOI 10.1016/0002-9610(82)90547-5
   BROWN SCW, 1986, BRIT J SURG, V73, P978, DOI 10.1002/bjs.1800731210
   Buimer MG, 2009, BRIT J SURG, V96, P350, DOI 10.1002/bjs.6569
   Büyükasik O, 2011, DERMATOL SURG, V37, P835, DOI [10.1111/j.1524-4725.2011.01961.x, 10.1111/j.1524-4725.2011.01961..x]
   CHAPMAN J, 1972, Journal of the National Medical Association, V64, P328
   Chen E, 2011, ANN PLAS SURG, V67, P397, DOI 10.1097/SAP.0b013e3181f77bd6
   CHING CC, 1965, DIS COLON RECTUM, V8, P349, DOI 10.1007/BF02627258
   Chuang CJ, 2004, J FORMOS MED ASSOC, V103, P644
   Civelek B, 2010, CENT EUR J MED, V5, P674, DOI 10.2478/s11536-009-0126-2
   Danby FW, 2015, J AM ACAD DERMATOL, V73, pS62, DOI 10.1016/j.jaad.2015.07.043
   Danby FW, 2010, J AM ACAD DERMATOL, V63, P481, DOI 10.1016/j.jaad.2010.01.033
   DeFazio MV, 2016, ANN PLAS SURG, V77, P217, DOI 10.1097/SAP.0000000000000584
   Elwood ET, 2001, ANN PLAS SURG, V46, P49, DOI 10.1097/00000637-200101000-00010
   Endo Y, 1998, BRIT J DERMATOL, V139, P906
   Falola RA, 2016, PLAST RECONSTR SURG, V138, p219S, DOI 10.1097/PRS.0000000000002671
   Fernandes NC, 2013, AN BRAS DERMATOL, V88, P480, DOI 10.1590/abd1806-4841.20131637
   Finley EM, 1996, J AM ACAD DERMATOL, V34, P465, DOI 10.1016/S0190-9622(96)90441-7
   Gonzaga TA, 2013, J BURN CARE RES, V34, P51, DOI 10.1097/BCR.0b013e31826a7be7
   GREELEY PW, 1951, PLAST RECONSTR SURG, V7, P143, DOI 10.1097/00006534-195102000-00007
   GROSSER A, 1982, J DERMATOL SURG ONC, V8, P391
   HARRISON BJ, 1987, BMJ-BRIT MED J, V294, P487, DOI 10.1136/bmj.294.6570.487
   HARRISON S H, 1964, Br J Plast Surg, V17, P95, DOI 10.1016/S0007-1226(64)80016-3
   HARTWELL SW, 1975, SURG CLIN N AM, V55, P1107
   Hazen PG, 2010, DERMATOL SURG, V36, P208, DOI 10.1111/j.1524-4725.2009.01427.x
   Herrmann A, 2000, CHIRURG, V71, P1395, DOI 10.1007/s001040070001
   Hudson DA, 1993, EUR J PLAST SURG
   Humphries LS, 2016, J PLAST RECONSTR AES, V69, P554, DOI 10.1016/j.bjps.2015.12.004
   Hurley H, 1989, DERMATOLOGIC SURG PR, pS729
   Hynes PJ, 2002, BRIT J PLAST SURG, V55, P507, DOI 10.1054/bjps.2002.3899
   Janse I, 2016, DERMATOL CLIN, V34, P97, DOI 10.1016/j.det.2015.08.007
   Janse IC, 2016, ACTA DERM-VENEREOL, V96, P390, DOI 10.2340/00015555-2258
   JEMEC GBE, 1988, J AM ACAD DERMATOL, V18, P1103, DOI 10.1016/S0190-9622(88)70113-9
   Jemec GBE, 2012, NEW ENGL J MED, V366, P158, DOI 10.1056/NEJMcp1014163
   Jianbing T, 2013, INT WOUND J
   Kagan RJ, 2005, SURGERY, V138, P734, DOI 10.1016/j.surg.2005.06.053
   Kirschke J, 2015, HAUTARZT, V66, P413, DOI 10.1007/s00105-015-3616-y
   Klipfel Adam, 2009, World J Surg, V33, P488, DOI 10.1007/s00268-008-9884-2
   KNAYSI GA, 1968, J AMER MED ASSOC, V203, P19, DOI 10.1001/jama.203.1.19
   Kohorst JJ, 2017, DERMATOL SURG, V43, P125, DOI 10.1097/DSS.0000000000000942
   Kohorst JJ, 2016, DERMATOL SURG, V42, P1030, DOI 10.1097/DSS.0000000000000806
   Kuo HW, 2003, DERMATOL SURG, V29, P173, DOI 10.1046/j.1524-4725.2003.29044.x
   Lapins J, 2002, J AM ACAD DERMATOL, V47, P280, DOI 10.1067/mjd.2002.124601
   Lin CH, 2016, DERMATOL SURG, V42, P273, DOI 10.1097/DSS.0000000000000609
   Madan V, 2008, BRIT J DERMATOL, V159, P1309, DOI 10.1111/j.1365-2133.2008.08932.x
   Mandal A, 2005, SURG-J R COLL SURG E, V3, P23, DOI 10.1016/S1479-666X(05)80006-X
   Martorell A, 2015, ACTAS DERMO-SIFILOGR, V106, P716, DOI 10.1016/j.ad.2015.06.005
   MASSON JK, 1969, SURG CLIN N AM, V49, P1043
   Mehdizadeh A, 2015, J AM ACAD DERMATOL, V73, pS70, DOI 10.1016/j.jaad.2015.07.044
   Melkun ET, 2005, PLAST RECONSTR SURG, V115, P1385, DOI 10.1097/01.PRS.0000157013.40191.91
   Menderes A, 2010, INT J MED SCI, V7, P240
   MORGAN WP, 1983, ANN ROY COLL SURG, V65, P235
   MORGAN WP, 1979, BRIT J SURG, V66, P853, DOI 10.1002/bjs.1800661206
   MORGAN WP, 1980, BRIT J SURG, V67, P277, DOI 10.1002/bjs.1800670416
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mustafa E B, 1980, J Natl Med Assoc, V72, P237
   OBRIEN J, 1976, PLAST RECONSTR SURG, V58, P354, DOI 10.1097/00006534-197609000-00017
   PALETTA F X, 1963, Plast Reconstr Surg, V31, P307, DOI 10.1097/00006534-196304000-00001
   Parks RW, 1997, ANN R COLL SURG ENGL, V79, P309
   POLLOCK WJ, 1972, PLAST RECONSTR SURG, V49, P22, DOI 10.1097/00006534-197201000-00004
   Rehman N, 2005, BRIT J PLAST SURG, V58, P441, DOI 10.1016/j.bjps.2004.10.022
   Rieger UM, 2009, J PLAST RECONSTR AES, V62, P1355, DOI 10.1016/j.bjps.2008.04.035
   Ritz JP, 1998, INT J COLORECTAL DIS, V13, P164, DOI 10.1007/s003840050159
   Rockwell WB, 2014, DERMATOL SURG, V40, P116, DOI 10.1111/dsu.12435
   Rompel R, 2000, DERMATOL SURG, V26, P638, DOI 10.1046/j.1524-4725.2000.00043.x
   Rosenfeld N, 1976, Plast Reconstr Surg, V58, P98, DOI 10.1097/00006534-197607000-00019
   Sabat R, 2017, HAUTARZT, V68, P994, DOI 10.1007/s00105-017-4079-0
   Scholl L, 2018, J CUTAN MED SURG
   Shah N, 2005, AM FAM PHYSICIAN, V72, P1547
   Shanmugam VK, 2017, INT J DERMATOL
   SILVERBERG B, 1987, PLAST RECONSTR SURG, V79, P555, DOI 10.1097/00006534-198704000-00007
   Soldin MG, 2000, BRIT J PLAST SURG, V53, P434, DOI 10.1054/bjps.1999.3285
   Sugio Y, 2016, PRS-GLOB OPEN, V4, DOI 10.1097/GOX.0000000000001128
   Takiyama H, 2015, INT J SURG CASE REP, V15, P107, DOI 10.1016/j.ijscr.2015.08.028
   Tanaka A, 2001, ANN PLAS SURG, V47, P636, DOI 10.1097/00000637-200112000-00010
   TASCHE C, 1975, PLAST RECONSTR SURG, V55, P559, DOI 10.1097/00006534-197505000-00005
   THORNTON JP, 1978, DIS COLON RECTUM, V21, P573, DOI 10.1007/BF02586399
   Unal C, 2011, MICROSURG, V31, P539, DOI 10.1002/micr.20918
   van der Zee HH, 2010, J AM ACAD DERMATOL, V63, P475, DOI 10.1016/j.jaad.2009.12.018
   van Hattem S, 2012, DERMATOL SURG, V38, P494, DOI 10.1111/j.1524-4725.2011.02255.x
   van Rappard DC, 2012, BRIT J DERMATOL, V167, P206, DOI 10.1111/j.1365-2133.2012.10807.x
   van Rappard DC, 2012, J EUR ACAD DERMATOL, V26, P898, DOI 10.1111/j.1468-3083.2011.04203.x
   WATSON JD, 1985, BRIT J PLAST SURG, V38, P567, DOI 10.1016/0007-1226(85)90022-0
   Weyandt G, 2005, HAUTARZT, V56, P1033, DOI 10.1007/s00105-005-1032-4
   WILTZ O, 1990, DIS COLON RECTUM, V33, P731, DOI 10.1007/BF02052316
   Wollina U, 2017, INT J DERMATOL, V56, P109, DOI 10.1111/ijd.13393
   Wollina U, 2012, DERMATOL SURG, V38, P110, DOI 10.1111/j.1524-4725.2011.02157.x
   Wormald JCR, 2014, J PLAST RECONSTR AES, V67, P1118, DOI 10.1016/j.bjps.2014.04.032
   Zouboulis CC, 2015, J EUR ACAD DERMATOL, V29, P619, DOI 10.1111/jdv.12966
   Zouboulis CC, 2012, J DTSCH DERMATOL GES, V10, ps1, DOI 10.1111/j.1610-0387.2012.08006.x
NR 109
TC 5
Z9 5
U1 0
U2 4
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0017-8470
EI 1432-1173
J9 HAUTARZT
JI Hautarzt
PD FEB
PY 2018
VL 69
IS 2
BP 149
EP 161
DI 10.1007/s00105-017-4114-1
PG 13
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA FV0SP
UT WOS:000424267800013
PM 29322225
DA 2026-07-24
ER

PT J
AU Tian, M
   Jiang, YZ
   Niu, YW
   Xiao, YR
   Lu, SL
   Wang, XQ
AF Tian, Ming
   Jiang, Yu-Zhi
   Niu, Yi-Wen
   Xiao, Yu-Rui
   Lu, Shu-Liang
   Wang, Xi-Qiao
TI A Severely Infected Diabetic Foot Treated Successfully Without Using
   Systemic Antibiotics
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE antibiotic; diabetic foot; infection
ID RESISTANT STAPHYLOCOCCUS-AUREUS; VACUUM-ASSISTED CLOSURE;
   INTERNATIONAL-CONSENSUS; PRACTICAL GUIDELINES; ULCERS; PREVENTION;
   FOUNDATION; MANAGEMENT; EXPRESSION; THERAPY
AB About 50% to 70% of all lower extremity amputations are related to diabetes infection. And antibiotic therapy is routinely used for all infected wounds to reduce the mortality of diabetic foot. Here, we report a case of diabetic foot with acute and deep severe infection. During hospital therapy, we used negative pressure therapy and extensive debridement without systemic antibiotic application, and we successfully rescued a foot from amputation. Negative pressure therapy and extensive debridement are very important and effective methods to control infection and promote wound healing in diabetes foot.
C1 [Tian, Ming; Jiang, Yu-Zhi; Niu, Yi-Wen; Xiao, Yu-Rui; Lu, Shu-Liang; Wang, Xi-Qiao] Jiao Tong Univ, Shanghai 200025, Peoples R China.
C3 Shanghai Jiao Tong University
RP Wang, XQ (通讯作者)，Jiao Tong Univ, Inst Burn, Ruijin Hosp, Sch Med, 197 Ruijin Rd, Shanghai 200025, Peoples R China.
EM boyamedicine@163.com
OI Tian, Ming/0000-0003-1665-321X
FU National Natural Science Foundation of China [30872686, 81071568];
   Shanghai Municipal Education Commission [11CXY38]
FX The author(s) disclosed receipt of the following financial support for
   the research, authorship, and/or publication of this article: This work
   was supported by grants from the National Natural Science Foundation of
   China (No. 30872686 and No. 81071568) and Scientific Innovation Project
   of Shanghai Municipal Education Commission (11CXY38).
CR Apelqvist J, 2008, DIABETES-METAB RES, V24, pS181, DOI 10.1002/dmrr.848
   Apelqvist J, 2000, DIABETES-METAB RES, V16, pS84, DOI 10.1002/1520-7560(200009/10)16:1+<::AID-DMRR113>3.0.CO;2-S
   Boulton AJM, 2005, LANCET, V366, P1719, DOI 10.1016/S0140-6736(05)67698-2
   Dang CN, 2003, DIABETIC MED, V20, P159, DOI 10.1046/j.1464-5491.2003.00860.x
   Erstad BL, 1997, VASCULAR SURG, V31, P419, DOI 10.1177/153857449703100403
   Kucan John O, 2005, J Burns Wounds, V4, pe3
   Lekas A, 2006, ANTICANCER RES, V26, P2989
   Lipsky BA, 1997, CLIN INFECT DIS, V24, P643, DOI 10.1093/clind/24.4.643
   Maghsoudi H, 2011, Ann Burns Fire Disasters, V24, P132
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Prompers L, 2008, DIABETOLOGIA, V51, P1826, DOI 10.1007/s00125-008-1089-6
   Rejzek A, 1998, ACTA CHIR AUST     S, V150, P12
   Schoppmann SF, 2006, BREAST CANCER RES TR, V99, P135, DOI 10.1007/s10549-006-9190-3
   Singh N, 2005, JAMA-J AM MED ASSOC, V293, P217, DOI 10.1001/jama.293.2.217
   Tentolouris N, 2006, CLIN MICROBIOL INFEC, V12, P186, DOI 10.1111/j.1469-0691.2005.01279.x
   Tentolouris N, 1999, DIABETIC MED, V16, P767, DOI 10.1046/j.1464-5491.1999.00132.x
   Vikatmaa P, 2008, EUR J VASC ENDOVASC, V36, P438, DOI 10.1016/j.ejvs.2008.06.010
NR 18
TC 6
Z9 7
U1 0
U2 16
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD DEC
PY 2012
VL 11
IS 4
BP 296
EP 298
DI 10.1177/1534734612458286
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 048KC
UT WOS:000311909200009
PM 23089961
DA 2026-07-24
ER

PT J
AU de Weerd, L
   Kjæve, J
   Nergård, S
AF de Weerd, Louis
   Kjaeve, Jorn
   Nergard, Solveig
TI The parachute design as a new extraperitoneal method of closing a
   recalcitrant high-output enterocutaneous fistula: report of a case
SO SURGERY TODAY
LA English
DT Article
DE Enterocutaneous fistula; Muscle flap; Vacuum-assisted closure system
ID GASTROINTESTINAL FISTULAS; MANAGEMENT; NUTRITION; SURGERY
AB We introduce a new method for closure of a recalcitrant high-output jejunal enterocutaneous fistula. First, a transposed rectus abdominis muscle is sutured into the fistula opening using a parachuting technique, then the muscle is covered with a skin graft and temporarily immobilized to the fistula wall and abdominal wall with a negative pressure device. This extraperitoneal method provides tension-free closure of the fistula with well-vascularized tissue, without compromising the intestinal lumen. No bowel is resected. This new technique allows for early mobilization and recommencement of enteral nutrition.
C1 [de Weerd, Louis; Nergard, Solveig] Univ Hosp N Norway, Dept Plast Surg & Hand Surg, N-9038 Tromso, Norway.
   [Kjaeve, Jorn] Univ Hosp N Norway, Dept Surg Gastroenterol, N-9038 Tromso, Norway.
C3 UiT The Arctic University of Tromso; University Hospital of North
   Norway; UiT The Arctic University of Tromso; University Hospital of
   North Norway
RP de Weerd, L (通讯作者)，Univ Hosp N Norway, Dept Plast Surg & Hand Surg, N-9038 Tromso, Norway.
EM louis.deweerd@unn.no
CR Chander J, 2004, WORLD J SURG, V28, P179, DOI 10.1007/s00268-003-7017-5
   Cohen M, 2006, CLIN PLAST SURG, V33, P295, DOI 10.1016/j.cps.2005.12.001
   de Weerd L, 2007, ANN PLAS SURG, V58, P580, DOI 10.1097/01.sap.0000237643.45125.8b
   Draus JM, 2006, SURGERY, V140, P570, DOI 10.1016/j.surg.2006.07.003
   Evenson AR, 2006, J GASTROINTEST SURG, V10, P455, DOI 10.1016/j.gassur.2005.08.001
   Gunn LA, 2006, ANN PLAS SURG, V57, P621, DOI 10.1097/01.sap.0000228966.13979.1c
   Lynch AC, 2004, ANN SURG, V240, P825, DOI 10.1097/01.sla.0000143895.17811.e3
   Makhdoom ZA, 2000, J CLIN GASTROENTEROL, V31, P195, DOI 10.1097/00004836-200010000-00003
   Martinez JL, 2008, WORLD J SURG, V32, P436, DOI 10.1007/s00268-007-9304-z
   Meguid MM, 1996, SURG CLIN N AM, V76, pR11, DOI 10.1016/S0039-6109(05)70494-1
   SOETERS PB, 1979, ANN SURG, V190, P189, DOI 10.1097/00000658-197908000-00012
   Visschers RGJ, 2008, WORLD J SURG, V32, P445, DOI 10.1007/s00268-007-9371-1
   Wainstein Daniel Edgardo, 2008, World J Surg, V32, P430
   Yasunaga H, 2009, SURG TODAY, V39, P663, DOI 10.1007/s00595-008-3848-x
NR 14
TC 3
Z9 3
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0941-1291
J9 SURG TODAY
JI Surg. Today
PD JUL
PY 2012
VL 42
IS 7
BP 681
EP 685
DI 10.1007/s00595-012-0128-6
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 958HD
UT WOS:000305226200011
PM 22294423
DA 2026-07-24
ER

PT J
AU Diener, H
   Wintzer, C
   Daum, H
   Debus, ES
AF Diener, Holger
   Wintzer, Christian
   Daum, Harald
   Debus, Eike Sebastian
TI Infections of chronical wounds: The diabetic foot - Systemic and local
   treatment options
SO CHIRURGISCHE GASTROENTEROLOGIE
LA German
DT Article
DE chronic wounds; ulcus entity; disturbing factors; wound infections;
   diabetic foot infections; wound healing strategies
ID OSTEOMYELITIS; ULCERS; DIAGNOSIS
AB Chronic wounds are results of various diseases. Evaluation and therapy of underlying disorders of chronic wounds must be the first step of successful wound healing. Bacterial colonization and infection of ischemic wounds and diabetic foot ulcers are limb-threatening factors. Therefore, a special therapy concept is necessary. The therapy is based on a sufficient wound bed preparation, moist wound dressings and vacuum-assisted closure ( VAC) therapy and infection control with systemic antibiotics in case of clinical infection. Another major point is the possibility of revascularization. This comprehensive wound care protocol can reduce the rate of major amputations.
C1 Asklepios Klin Harburg, Wundzentrum, Gefasszentrum, Abt Allgemein Gefass & Visceralchirurg, D-21079 Hamburg, Germany.
RP Diener, H (通讯作者)，Asklepios Klin Harburg, Wundzentrum, Gefasszentrum, Abt Allgemein Gefass & Visceralchirurg, Eissendorfer Pferdeweg 51, D-21079 Hamburg, Germany.
EM holger_diener@yahoo.de
CR APELQVIST J, 1993, J INTERN MED, V233, P485, DOI 10.1111/j.1365-2796.1993.tb01003.x
   Boulton AJM, 1996, DIABETIC MED, V13, pS12, DOI 10.1002/dme.1996.13.s1.12
   Chantelau E, 1996, DIABETIC MED, V13, P156, DOI 10.1002/(SICI)1096-9136(199602)13:2<156::AID-DIA59>3.0.CO;2-U
   Coerper S, 2004, CHIRURG, V75, P471, DOI 10.1007/s00104-004-0843-7
   CUNHA BA, 1997, EMERGEN MED, V10, P115
   DAUBENER W, 2005, ARZTEZEITUNG ON 1212
   Falanga V, 2005, LANCET, V366, P1736, DOI 10.1016/S0140-6736(05)67700-8
   GRAYSON ML, 1995, JAMA-J AM MED ASSOC, V273, P721, DOI 10.1001/jama.273.9.721
   Hornberg C, 2003, ORTHOPADE, V32, P218, DOI 10.1007/s00132-003-0456-8
   International Working Group on the Diabetic Foot, 2003, INT CONS DIAB FOOT C
   Lipsky BA, 2004, CLIN INFECT DIS, V38, P17, DOI 10.1086/380449
   Lipsky BA, 2004, CLIN INFECT DIS, V39, P885, DOI 10.1086/383271
   Lipsky BA, 1997, CLIN INFECT DIS, V25, P1318, DOI 10.1086/516148
   LOBMANN R, 2001, DIABETISCHES FUSSSYN
   Morbach S, 2004, DIABETES STOFFWECH H, V13, P9
   Murray HJ, 1996, DIABETIC MED, V13, P979, DOI 10.1002/(SICI)1096-9136(199611)13:11<979::AID-DIA267>3.3.CO;2-1
   NEWMAN LG, 1991, JAMA-J AM MED ASSOC, V266, P1246, DOI 10.1001/jama.266.9.1246
   Pellizzer G, 2001, DIABETIC MED, V18, P822, DOI 10.1046/j.1464-5491.2001.00584.x
   PROBST W, 2004, WUNDMANAGEMENT LEITF
   Rümenapf G, 2003, ZBL CHIR, V128, P726
   RUMENAPF G, 2002, GEFASSCHIRURGIE, V7, P128
   SCHNELL O, 2001, KLIN MAGAZIN
   Sellmer W, 2005, MED PRAXIS, V6, P56
   Senneville E, 2001, J ANTIMICROB CHEMOTH, V48, P927, DOI 10.1093/jac/48.6.927
   *SIGN NR 26, 2003, GEFASSCHRIRURG, V8, P288
   SPRAUL M, 1999, INT KONSENSUS DIABET
   STENGEL D, 2005, CHEMOTHERAPIE J, V14, P191
   TIGGES W, 2006, HAMBURGER ARZTEBL, V6, P340
   Tooke JE, 1996, DIABETIC MED, V13, pS26, DOI 10.1002/dme.1996.13.s1.26
   TRAUTENHAHN J, 2004, CHIRURG, V75, P492
   Weigelt J, 2005, ANTIMICROB AGENTS CH, V49, P2260, DOI 10.1128/AAC.49.6.2260-2266.2005
NR 31
TC 2
Z9 2
U1 2
U2 11
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 0177-9990
J9 CHIR GASTROENTEROL
JI Chir. Gastroenterol.
PY 2006
VL 22
IS 3
BP 127
EP 137
DI 10.1159/000094583
PG 11
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 125SV
UT WOS:000243463700003
DA 2026-07-24
ER

PT J
AU Childs, DR
   Murthy, AS
AF Childs, Dylan R.
   Murthy, Ananth S.
TI Overview of Wound Healing and Management
SO SURGICAL CLINICS OF NORTH AMERICA
LA English
DT Article
DE Wound; Healing; Management; Skin; Soft tissue injuries
ID VACUUM-ASSISTED CLOSURE; EHLERS-DANLOS-SYNDROME; DOG-BITE INJURIES;
   WERNERS-SYNDROME; SURFACE ANATOMY; GROWTH-FACTORS; RECONSTRUCTION;
   EXPERIENCE; INFECTION; DEFECTS
AB Wound healing is a highly complex chain of events, and although it may never be possible to eliminate the risk of experiencing a wound, clinicians' armamentarium continues to expand with methods to manage it. The phases of wound healing are the inflammatory phase, the proliferative phase, and the maturation phase. The pathway of healing is determined by characteristics of the wound on initial presentation, and it is vital to select the appropriate method to treat the wound based on its ability to avoid hypoxia, infection, excessive edema, and foreign bodies.
C1 [Childs, Dylan R.] Summa Hlth Syst, Div Plast Surg, 525 E Market St, Akron, OH 44304 USA.
   [Murthy, Ananth S.] Akron Childrens Hosp, Div Plast Surg, 215 W Bowery St, Akron, OH 44308 USA.
C3 Summa Health System; Akron Children's Hospital
RP Murthy, AS (通讯作者)，Akron Childrens Hosp, Plast & Reconstruct Surg, 215 West Bowery St,Suite 3300, Akron, OH 44308 USA.
EM amurthy@chmca.org
CR [Anonymous], WOUND HEALING SKIN E
   [Anonymous], PHYSL BASIS SURGERY
   Arnold M, 2006, PLAST RECONSTR SURG, V117, p42S, DOI 10.1097/01.prs.0000225432.17501.6c
   Atiyeh BS, 2003, AESTHET PLAST SURG, V27, P411, DOI 10.1007/s00266-003-3049-3
   Attinger CE, 2006, PLAST RECONSTR SURG, V117, p72S, DOI 10.1097/01.prs.0000225470.42514.8f
   BAILIE WE, 1978, J CLIN MICROBIOL, V7, P223
   Barrientos S, 2008, WOUND REPAIR REGEN, V16, P585, DOI 10.1111/j.1524-475X.2008.00410.x
   BAUER EA, 1986, SCIENCE, V234, P1240, DOI 10.1126/science.3022382
   Beighton P, 1998, AM J MED GENET, V77, P31, DOI 10.1002/(SICI)1096-8628(19980428)77:1<31::AID-AJMG8>3.3.CO;2-P
   Broughton G., 2006, PLAST RECONSTR SURG, V117, DOI [DOI 10.1097/01.PRS.0000222562.60260.F9, 10.1097/01.prs.0000222562.60260.f9]
   Bryan CS, 2013, TEX HEART I J, V40, P125
   Burch GH, 1997, NAT GENET, V17, P104, DOI 10.1038/ng0997-104
   Butler PD, 2008, J AM COLL SURGEONS, V206, P731, DOI 10.1016/j.jamcollsurg.2007.12.001
   Bütter A, 2006, J PEDIATR SURG, V41, P940, DOI 10.1016/j.jpedsurg.2006.01.061
   Capanna R, 1993, ORTHOPEDICS TRAUMATO, V2, P159, DOI DOI 10.1007/BF02620523
   CUMMINGS P, 1994, ANN EMERG MED, V23, P535, DOI 10.1016/S0196-0644(94)70073-7
   Donelan MB, 2008, ANN PLAS SURG, V60, P480, DOI 10.1097/SAP.0b013e31816fcad5
   Dorafshar AH, 2013, PLAST RECONSTR SURG, V131, P253, DOI 10.1097/PRS.0b013e3182778753
   EHRLICH HP, 1968, ANN SURG, V167, P324, DOI 10.1097/00000658-196803000-00004
   Erba P, 2011, ANN SURG, V253, P402, DOI 10.1097/SLA.0b013e31820563a8
   Falagas ME, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0064741
   Ferri FF, 2012, FERRIS CLIN ADVISOR
   Fleisher GR, 1999, NEW ENGL J MED, V340, P138, DOI 10.1056/NEJM199901143400210
   Fonder MA, 2008, J AM ACAD DERMATOL, V58, P185, DOI 10.1016/j.jaad.2007.08.048
   Garvey EM, 2015, J PEDIATR SURG, V50, P343, DOI 10.1016/j.jpedsurg.2014.09.051
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Goldman Robert, 2004, Adv Skin Wound Care, V17, P24, DOI 10.1097/00129334-200401000-00012
   Guo L, 2008, PLAST RECONSTR SURG, V122, p130E, DOI 10.1097/PRS.0b013e31818823c7
   Gurunluoglu R, 2014, J TRAUMA ACUTE CARE, V76, P1294, DOI 10.1097/TA.0000000000000185
   Hart DW, 2003, J TRAUMA, V54, P755, DOI 10.1097/01.TA.0000060260.61478.A7
   Heit YI, 2012, PLAST RECONSTR SURG, V129, P589, DOI 10.1097/PRS.0b013e3182402c89
   Hopf H W, 2001, Foot Ankle Clin, V6, P661, DOI 10.1016/S1083-7515(02)00008-6
   Hurvitz KA, 2006, PLAST RECONSTR SURG, V118, p122E, DOI 10.1097/01.prs.0000237094.58891.fb
   Ingber D E, 2004, Mech Chem Biosyst, V1, P53
   Ingber DE, 2005, P NATL ACAD SCI USA, V102, P11571, DOI 10.1073/pnas.0505939102
   Innocenti M, 2009, MICROSURG, V29, P361, DOI 10.1002/micr.20668
   Jandali S, 2011, PLAST RECONSTR SURG, V127, P1932, DOI 10.1097/PRS.0b013e31820cf4a6
   Kaye AE, 2009, PLAST RECONSTR SURG, V124, P551, DOI 10.1097/PRS.0b013e3181addad9
   Kretlow James D, 2010, Semin Plast Surg, V24, P348, DOI 10.1055/s-0030-1269764
   KUDSK KA, 1981, J TRAUMA, V21, P835, DOI 10.1097/00005373-198110000-00002
   Lansdown ABG, 2007, WOUND REPAIR REGEN, V15, P2, DOI 10.1111/j.1524-475X.2006.00179.x
   LEBWOHL M, 1994, J AM ACAD DERMATOL, V30, P103, DOI 10.1016/S0190-9622(08)81894-4
   Lech M, 2013, BBA-MOL BASIS DIS, V1832, P989, DOI 10.1016/j.bbadis.2012.12.001
   Leininger BE, 2006, J TRAUMA, V61, P1207, DOI 10.1097/01.ta.0000241150.15342.da
   Lewis T, 1924, HEART-J STUD CIRC, V11, P209
   Lopez G, 2008, J PEDIATR SURG, V43, P2202, DOI 10.1016/j.jpedsurg.2008.08.067
   Lu F, 2011, ANN PLAS SURG, V66, P296, DOI 10.1097/SAP.0b013e3181ea1e9b
   MILLER GDH, 1976, PLAST RECONSTR SURG, V58, P133, DOI 10.1097/00006534-197608000-00001
   Moran SL, 2006, PLAST RECONSTR SURG, V118, P413, DOI 10.1097/01.prs.0000227682.71527.2b
   Moran SL, 2009, MICROSURG, V29, P393, DOI 10.1002/micr.20655
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Noaman HH, 2013, ANN PLAS SURG, V71, P503, DOI 10.1097/SAP.0b013e3182a1aff0
   Ogawa R, 2010, PLAST RECONSTR SURG, V125, P557, DOI 10.1097/PRS.0b013e3181c82dd5
   Ogawa R, 2009, ANN PLAS SURG, V62, P104, DOI 10.1097/SAP.0b013e3181855172
   Othman Diaa, 2012, Plast Surg Int, V2012, P374398, DOI 10.1155/2012/374398
   PADH H, 1991, NUTR REV, V49, P65, DOI 10.1111/j.1753-4887.1991.tb07407.x
   PATTERSON J.W., 2014, Elsevier Health Sciences
   Pauniaho SL, 2009, J PEDIATR SURG, V44, P1736, DOI 10.1016/j.jpedsurg.2009.01.009
   Pepin M, 2000, NEW ENGL J MED, V342, P673, DOI 10.1056/NEJM200003093421001
   Piper M, 2016, J PLAST RECONSTR AES, V69, P91, DOI 10.1016/j.bjps.2015.08.035
   QUINN JV, 1993, ANN EMERG MED, V22, P1130, DOI 10.1016/S0196-0644(05)80977-1
   Raja Sivamani K., 2007, FRONT BIOSCI-LANDMRK, V12, P2249
   Reinke JM, 2012, EUR SURG RES, V49, P35, DOI 10.1159/000339613
   Rhee ST, 2004, PEDIATR EMERG CARE, V20, P40, DOI 10.1097/01.pec.0000106243.72265.f6
   Rim WJH, 1998, ARCH PHARM RES, V21, P487, DOI 10.1007/BF02975363
   Rohrich RJ, 2000, PLAST RECONSTR SURG, V105, P202, DOI 10.1097/00006534-200001000-00036
   SALK D, 1982, HUM GENET, V62, P1, DOI 10.1007/BF00295598
   Schulz C, 2012, SCIENCE, V336, P86, DOI 10.1126/science.1219179
   Singer AJ, 1997, NEW ENGL J MED, V337, P1142, DOI 10.1056/NEJM199710163371607
   Smith J, 2003, ARCH DIS CHILD, V88, P83, DOI 10.1136/adc.88.1.83
   Steffen A, 2006, PLAST RECONSTR SURG, V118, P1358, DOI 10.1097/01.prs.0000239539.98956.b0
   Stringer MD, 2012, PLAST RECONSTR SURG, V130, P1032, DOI 10.1097/PRS.0b013e318267d610
   SUDARSKY LA, 1987, ANN SURG, V206, P661
   Sung K, 2004, ANN THORAC SURG, V77, P1371, DOI 10.1016/j.athoracsur.2003.06.020
   Tabbutt S, 1997, J THORAC CARDIOV SUR, V113, P886, DOI 10.1016/S0022-5223(97)70261-7
   Tandara AA, 2004, WORLD J SURG, V28, P294, DOI 10.1007/s00268-003-7400-2
   Thorne CH., 2013, Grabb and Smith's plastic surgery, V7th
   Tzafetta K, 2010, PLAST RECONSTR SURG, V125, P879, DOI 10.1097/PRS.0b013e3181ccdc78
   Upton J, 2008, PLAST RECONSTR SURG, V121, P1725, DOI 10.1097/PRS.0b013e31816c3b81
   Upton Joseph, 2009, Plast Reconstr Surg, V124, pe313, DOI 10.1097/PRS.0b013e3181bf83f1
   Viol A, 2009, PLAST RECONSTR SURG, V123, P1256, DOI 10.1097/PRS.0b013e31819f2b5e
   Vyas RM, 2013, PLAST RECONSTR SURG, V131, P544, DOI 10.1097/PRS.0b013e31827c6e2e
   Wolter TP, 2005, BRIT J PLAST SURG, V58, P416, DOI 10.1016/j.bjps.2004.04.008
   Wong CH, 2009, PLAST RECONSTR SURG, V124, P500, DOI 10.1097/PRS.0b013e3181addb11
   Woodward CS, 2011, ANN THORAC SURG, V91, P799, DOI 10.1016/j.athoracsur.2010.10.030
   Wright JB, 1998, AM J INFECT CONTROL, V26, P572, DOI 10.1053/ic.1998.v26.a93527
   ZAIZEN Y, 1990, J SURG RES, V49, P333, DOI 10.1016/0022-4804(90)90032-W
   Zhang MC, 1999, J BIOL CHEM, V274, P981, DOI 10.1074/jbc.274.2.981
NR 88
TC 162
Z9 201
U1 2
U2 78
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0039-6109
EI 1558-3171
J9 SURG CLIN N AM
JI Surg. Clin.-North Am.
PD FEB
PY 2017
VL 97
IS 1
BP 189
EP +
DI 10.1016/j.suc.2016.08.013
PG 20
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EH4YK
UT WOS:000391779600015
PM 27894427
DA 2026-07-24
ER

PT J
AU Miller, AO
   Henry, M
AF Miller, Andy O.
   Henry, Michael
TI Update in Diagnosis and Treatment of Diabetic Foot Infections
SO PHYSICAL MEDICINE AND REHABILITATION CLINICS OF NORTH AMERICA
LA English
DT Article
DE Diabetic foot ulcer; Diabetic foot infection; Review; Osteomyelitis;
   Diabetes; Antibiotics
ID ERYTHROCYTE SEDIMENTATION-RATE; RANDOMIZED CONTROLLED-TRIAL;
   VACUUM-ASSISTED-CLOSURE; PRESSURE WOUND THERAPY; CHRONIC OSTEOMYELITIS;
   UNDERLYING OSTEOMYELITIS; NONSURGICAL MANAGEMENT; ANTIMICROBIAL THERAPY;
   SURGICAL-TREATMENT; MULTICENTER TRIAL
AB Foot infections are a major cause of morbidity and mortality in diabetics. Evaluation of diabetic foot infections often requires clinical, radiologic, laboratory, and microbiologic assessment. Osteomyelitis has a profound impact on the prognosis and management of these infections, and diagnosis can be difficult; the gold standard remains bone biopsy. Despite a panoply of studies, the optimal management of diabetic foot infections remains poorly understood. Antibiotics, surgery, rehabilitation and/or off-loading, and glycemic control remain the cornerstones of treatment; alternative therapies remain largely unproven.
C1 [Miller, Andy O.; Henry, Michael] Bronx Lebanon Hosp Ctr, Dept Med, Div Infect Dis, Bronx, NY 10457 USA.
C3 BronxCare Health System
RP Miller, AO (通讯作者)，Bronx Lebanon Hosp Ctr, Dept Med, Div Infect Dis, 1650 Grand Concourse,8th Floor, Bronx, NY 10457 USA.
EM amiller@bronxleb.org
RI Miller, Andy/AAE-2500-2022
CR [Anonymous], 2002, MORB MORTAL WKLY, V51, P902
   [Anonymous], 1995, NATL DIABETES DATA G
   Aragón-Sánchez FJ, 2008, DIABETOLOGIA, V51, P1962, DOI 10.1007/s00125-008-1131-8
   Armstrong D G, 1996, J Foot Ankle Surg, V35, P280
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Armstrong DG, 1996, J AM PODIAT MED ASSN, V86, P224, DOI 10.7547/87507315-86-5-224
   ARMSTRONG DG, 1996, J AM PODIAT MED ASSN, V86, P14
   ARMSTRONG DG, 1996, J FOOT ANKLE SURG, V35, P14
   BAAL JG, 2004, CLIN INFECT DIS   S2, V39, pS123
   Berendt AR, 2008, DIABETES-METAB RES, V24, pS145, DOI 10.1002/dmrr.836
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Cruciani M, 2005, DIABETES CARE, V28, P454, DOI 10.2337/diacare.28.2.454
   Delcourt A, 2005, DIABETES METAB, V31, P125, DOI 10.1016/S1262-3636(07)70178-7
   Dinh MT, 2008, CLIN INFECT DIS, V47, P519, DOI 10.1086/590011
   Dowd SE, 2008, PLOS ONE, V3, DOI 10.1371/journal.pone.0003326
   Eldor R, 2004, DIABETIC MED, V21, P1161, DOI 10.1111/j.1464-5491.2004.01358.x
   Eneroth M, 1997, FOOT ANKLE INT, V18, P716, DOI 10.1177/107110079701801107
   Eneroth M, 2008, DIABETES-METAB RES, V24, pS76, DOI 10.1002/dmrr.852
   Esposito S, 2008, DIABETIC MED, V25, P979, DOI 10.1111/j.1464-5491.2008.02507.x
   Fleischer AE, 2009, J FOOT ANKLE SURG, V48, P39, DOI 10.1053/j.jfas.2008.09.003
   Game FL, 2008, DIABETOLOGIA, V51, P962, DOI 10.1007/s00125-008-0976-1
   Game F, 2008, DIABETES-METAB RES, V24, pS72, DOI 10.1002/dmrr.816
   GRAYSON ML, 1995, JAMA-J AM MED ASSOC, V273, P721, DOI 10.1001/jama.273.9.721
   Henke PK, 2005, ANN SURG, V241, P885, DOI 10.1097/01.sla.0000164172.28918.3f
   International Diabetes Federation, DIAB, V9th
   Jeffcoate WJ, 2004, CLIN INFECT DIS, V39, pS115, DOI 10.1086/383272
   Johnston BL, 2007, CAN J INFECT DIS MED, V18, P115, DOI 10.1155/2007/968523
   Kaleta JL, 2001, J AM PODIAT MED ASSN, V91, P445, DOI 10.7547/87507315-91-9-445
   Karr JC, 2002, J AM PODIAT MED ASSN, V92, P314, DOI 10.7547/87507315-92-5-314
   Keidar Z, 2005, J NUCL MED, V46, P444
   Kessler L, 2006, DIABETIC MED, V23, P99, DOI 10.1111/j.1464-5491.2005.01764.x
   Khanolkar MP, 2008, QJM-INT J MED, V101, P685, DOI 10.1093/qjmed/hcn027
   Khatri G, 2001, AM J MED SCI, V321, P367, DOI 10.1097/00000441-200106000-00002
   Kuck EM, 1998, FOOT ANKLE INT, V19, P38, DOI 10.1177/107110079801900107
   Larsson J, 1998, CLIN ORTHOP RELAT R, P149
   Lavery LA, 2007, CLIN INFECT DIS, V44, P562, DOI 10.1086/511036
   Lavery LA, 2006, DIABETES CARE, V29, P1288, DOI 10.2337/dc05-2425
   Lavery LA, 2009, DIABETES RES CLIN PR, V83, P347, DOI 10.1016/j.diabres.2008.11.030
   Lazzarini L, 2005, INT J INFECT DIS, V9, P127, DOI 10.1016/j.ijid.2004.09.009
   LEVIN ME, 2008, LEVIN ONEALS DIABETI, pR11
   Lipsky BA, 2007, CLIN MICROBIOL INFEC, V13, P351, DOI 10.1111/j.1469-0691.2007.01697.x
   LIPSKY BA, 1990, ARCH INTERN MED, V150, P790, DOI 10.1001/archinte.150.4.790
   Lipsky BA, 2004, CLIN INFECT DIS, V38, P17, DOI 10.1086/380449
   Lipsky BA, 2004, CLIN INFECT DIS, V39, P885, DOI 10.1086/383271
   Lipsky BA, 1997, CLIN INFECT DIS, V25, P1318, DOI 10.1086/516148
   Lipsky BA, 2005, LANCET, V366, P1695, DOI 10.1016/S0140-6736(05)67694-5
   LIPSKY BA, 1997, CLIN INFECT DIS, V25, P14
   Lipsky BA, 2008, LEVIN ONEALS DIABETI, P305
   Lipsky BA, 2008, DIABETES-METAB RES, V24, pS66, DOI 10.1002/dmrr.828
   Lipsky BA, 2008, CLIN INFECT DIS, V47, P1537, DOI 10.1086/593185
   MACKOWIAK PA, 1978, JAMA-J AM MED ASSOC, V239, P2772, DOI 10.1001/jama.239.26.2772
   Moran GJ, 2006, NEW ENGL J MED, V355, P666, DOI 10.1056/NEJMoa055356
   Nelson EA, 2006, DIABETIC MED, V23, P348, DOI 10.1111/j.1464-5491.2006.01785.x
   PECORARO RE, 1991, DIABETES, V40, P1305, DOI 10.2337/diabetes.40.10.1305
   Peters EJG, 2005, J DIABETES COMPLICAT, V19, P107, DOI 10.1016/j.jdiacomp.2004.06.002
   Rajbhandari SM, 2000, DIABETIC MED, V17, P74, DOI 10.1046/j.1464-5491.2000.00194.x
   Rauwerda JA, 2004, DIABETES-METAB RES, V20, pS41, DOI 10.1002/dmrr.475
   Raymakers JT, 2001, DIABETIC MED, V18, P229, DOI 10.1046/j.1464-5491.2001.00460.x
   REIBER GE, 1992, ANN INTERN MED, V117, P97, DOI 10.7326/0003-4819-117-2-97
   ROECKLWIEDMANN I, BR J SURG, V92, P24
   Sarikaya A, 2003, ANN NUCL MED, V17, P669, DOI 10.1007/BF02984973
   Senneville E, 2006, CLIN INFECT DIS, V42, P57, DOI 10.1086/498112
   Senneville E, 2008, DIABETES CARE, V31, P637, DOI 10.2337/dc07-1744
   Sotto A, 2008, DIABETES CARE, V31, P2318, DOI 10.2337/dc08-1010
   Tan JS, 1996, CLIN INFECT DIS, V23, P286, DOI 10.1093/clinids/23.2.286
   Wrobel JS, 1998, J AM PODIAT MED ASSN, V88, P337, DOI 10.7547/87507315-88-7-337
   Zuluaga AF, 2006, ARCH INTERN MED, V166, P95, DOI 10.1001/archinte.166.1.95
   Zuluaga AF, 2002, BMC INFECT DIS, V2, DOI 10.1186/1471-2334-2-8
NR 68
TC 10
Z9 12
U1 0
U2 9
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1047-9651
J9 PHYS MED REHABIL CLI
JI Phys. Med. Rehabil. Clin. N. Am.
PD NOV
PY 2009
VL 20
IS 4
BP 611
EP +
DI 10.1016/j.pmr.2009.06.007
PG 16
WC Rehabilitation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Rehabilitation
GA 509NI
UT WOS:000271024300004
PM 19781502
DA 2026-07-24
ER

PT J
AU Waibel, BH
   Rotondo, MF
AF Waibel, Brett H.
   Rotondo, Michael F.
TI Damage Control for Intra-Abdominal Sepsis
SO SURGICAL CLINICS OF NORTH AMERICA
LA English
DT Article
DE Damage control; Abdominal sepsis; Complications
ID ABDOMINAL COMPARTMENT SYNDROME; CRITICALLY-ILL PATIENTS; INTENSIVE
   INSULIN THERAPY; VACUUM-ASSISTED CLOSURE; OPEN ABDOMEN MANAGEMENT;
   HEART-RATE-VARIABILITY; DIMINISHED PHYSIOLOGICAL RESERVE; MECHANICALLY
   VENTILATED PATIENTS; INFLAMMATORY GENE-TRANSCRIPTION; RANDOMIZED
   CONTROLLED-TRIAL
AB With the success of damage-control surgery for the treatment of exsanguinating truncal trauma, it has been adapted to other surgical diseases associated with shock states, such as severe secondary peritonitis. The structured approach of damage control is easily adapted to and can incorporate the fundamental elements of the Surviving Sepsis Campaign. It is not meant to replace tried and true surgical principles, such as source control, but is a usable framework in managing the complicated circumstances seen with these patients.
C1 [Waibel, Brett H.; Rotondo, Michael F.] E Carolina Univ, Brody Sch Med, Dept Surg, Greenville, NC 27834 USA.
C3 University of North Carolina; East Carolina University
RP Waibel, BH (通讯作者)，E Carolina Univ, Brody Sch Med, Dept Surg, 600 Moye Blvd, Greenville, NC 27834 USA.
EM brett.waibel@pcmh.com
CR Adkins AL, 2004, AM SURGEON, V70, P137
   Al-Khoury G, 2008, J AM COLL SURGEONS, V206, P397, DOI 10.1016/j.jamcollsurg.2007.07.027
   Anderson O, 2011, COLORECTAL DIS, V13, pe20, DOI 10.1111/j.1463-1318.2010.02441.x
   Aoki N, 2000, AM J SURG, V180, P540, DOI 10.1016/S0002-9610(00)00497-9
   Aoki N, 2000, AM J SURG, V180, P544
   Arabi YM, 2008, CRIT CARE MED, V36, P3190, DOI 10.1097/CCM.0b013e31818f21aa
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1997, ANN PLAST SURG, V38, P577
   Asensio JA, 2004, ARCH SURG-CHICAGO, V139, P209, DOI 10.1001/archsurg.139.2.209
   Asensio JA, 2001, AM J SURG, V182, P743, DOI 10.1016/S0002-9610(01)00809-1
   Asensio JA, 2004, ARCH SURG, V139, P215
   Balogh Z, 2003, ARCH SURG-CHICAGO, V138, P637, DOI 10.1001/archsurg.138.6.637
   Barie PS, 2004, AM J SURG, V188, P212, DOI 10.1016/j.amjsurg.2004.06.008
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   BARNES GE, 1985, AM J PHYSIOL, V248, pR208, DOI 10.1152/ajpregu.1985.248.2.R208
   Behbehani NA, 1999, CHEST, V115, P1627
   Bendjelid K, 2003, INTENS CARE MED, V29, P352, DOI 10.1007/s00134-002-1615-9
   Biffl WL, 2001, AM J SURG, V182, P645, DOI 10.1016/S0002-9610(01)00814-5
   Birkhahn RH, 2005, AM J EMERG MED, V23, P323, DOI 10.1016/j.ajem.2005.02.029
   Bosscha K, 2000, EUR J SURG, V166, P44
   BROCK WB, 1995, AM SURGEON, V61, P30
   Brower RG, 2000, NEW ENGL J MED, V342, P1301, DOI 10.1056/nejm200005043421801
   Brunkhorst FM, 2008, NEW ENGL J MED, V358, P125, DOI 10.1056/NEJMoa070716
   Buijk SE, 2002, INTENS CARE MED, V28, P1024, DOI 10.1007/s00134-002-1383-6
   Bunn F, 2004, COCHRANE DB SYST REV, V3, DOI DOI 10.1002/146151858.CD002045.PUB2
   Burch JM, 1996, SURG CLIN N AM, V76, P833, DOI 10.1016/S0039-6109(05)70483-7
   BURCH JM, 1992, ANN SURG, V215, P476, DOI 10.1097/00000658-199205000-00010
   Calandra T, 2005, CRIT CARE MED, V33, P1538, DOI 10.1097/01.CCM.0000168253.91200.83
   Chang MC, 1998, J TRAUMA, V44, P440, DOI 10.1097/00005373-199803000-00002
   Cheatham ML, 2010, CRIT CARE MED, V38, P402, DOI 10.1097/CCM.0b013e3181b9e9b1
   Cheatham ML, 1998, CRIT CARE MED, V26, P1801, DOI 10.1097/00003246-199811000-00017
   Cheatham ML, 1999, J TRAUMA, V46, P16, DOI 10.1097/00005373-199901000-00004
   Choi PTL, 1999, CRIT CARE MED, V27, P200, DOI 10.1097/00003246-199901000-00053
   CHRISTOU NV, 1993, ARCH SURG-CHICAGO, V128, P193
   Chromik AM, 2009, J GASTROINTEST SURG, V13, P1358, DOI 10.1007/s11605-009-0882-y
   Ciesla DJ, 2005, ARCH SURG-CHICAGO, V140, P432, DOI 10.1001/archsurg.140.5.432
   Cinat ME, 1999, ARCH SURG-CHICAGO, V134, P964, DOI 10.1001/archsurg.134.9.964
   Cipolla J, 2005, AM SURGEON, V71, P202
   Collier B, 2007, JPEN-PARENTER ENTER, V31, P410, DOI 10.1177/0148607107031005410
   Connolly PT, 2008, ANN SURG, V247, P440, DOI 10.1097/SLA.0b013e3181612c99
   COOPER DJ, 1990, ANN INTERN MED, V112, P492, DOI 10.7326/0003-4819-112-7-492
   Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
   de Jonghe Bernard, 2009, Crit Care Med, V37, pS309, DOI 10.1097/CCM.0b013e3181b6e64c
   De Keulenaer BL, 2011, AM SURGEON, V77, pS17
   De Keulenaer BL, 2011, AM SURGEON, V77, pS34
   De Laet IE, 2008, LANGENBECK ARCH SURG, V393, P833, DOI 10.1007/s00423-008-0347-x
   De la Rosa GD, 2008, CRIT CARE, V12, DOI 10.1186/cc7017
   Dellinger RP, 2008, CRIT CARE MED, V36, P296, DOI 10.1097/01.CCM.0000298158.12101.41
   Dissanaike S, 2008, J AM COLL SURGEONS, V207, P690, DOI 10.1016/j.jamcollsurg.2008.06.332
   EIDELMAN Y, 1994, J TRAUMA, V37, P677, DOI 10.1097/00005373-199410000-00025
   Ennis LS, 2003, AM SURGEON, V69, P733
   Erdmann D, 2001, PLAST RECONSTR SURG, V108, P2066, DOI 10.1097/00006534-200112000-00036
   Ertel W, 2000, CRIT CARE MED, V28, P1747, DOI 10.1097/00003246-200006000-00008
   Evans H L, 2001, Curr Opin Crit Care, V7, P117, DOI 10.1097/00075198-200104000-00010
   FABIAN TC, 1994, ANN SURG, V219, P643, DOI 10.1097/00000658-199406000-00007
   Feliciano DV, 1991, ADV TRAUMA CRITICAL, V6, P231
   Finfer S, 2004, NEW ENGL J MED, V350, P2247
   Finfer S, 2009, NEW ENGL J MED, V360, P1283, DOI 10.1056/NEJMoa0810625
   Finlay IG, 2004, BJS-BRIT J SURG, V91, P83, DOI 10.1002/bjs.4434
   Gajic O, 2004, CRIT CARE MED, V32, P1817, DOI 10.1097/01.CCM.0000133019.52531.30
   Garner GB, 2001, AM J SURG, V182, P630, DOI 10.1016/S0002-9610(01)00786-3
   Giesbrecht G G, 2001, Emerg Med (Fremantle), V13, P9
   Goverman J, 2006, J TRAUMA, V60, P428, DOI 10.1097/01.ta.0000203588.66012.c4
   Griesdale DEG, 2009, CAN MED ASSOC J, V180, P821, DOI 10.1503/cmaj.090206
   Hall Jesse B, 2009, Crit Care Med, V37, pS416, DOI 10.1097/CCM.0b013e3181b6f95b
   HAU T, 1995, ARCH SURG-CHICAGO, V130, P1193
   Hildebrand F, 2004, AM J SURG, V187, P363, DOI 10.1016/j.amjsurg.2003.12.016
   Ho AMH, 2001, J TRAUMA, V51, P173, DOI 10.1097/00005373-200107000-00033
   Hoey B A, 2002, Scand J Surg, V91, P92
   Horwood J, 2009, ANN ROY COLL SURG, V91, P681, DOI 10.1308/003588409X12486167520993
   Ivatury RR, 1998, J TRAUMA, V44, P1016, DOI 10.1097/00005373-199806000-00014
   Ivy ME, 2000, J TRAUMA, V49, P387, DOI 10.1097/00005373-200009000-00001
   Jamshidi R, 2007, ARCH SURG-CHICAGO, V142, P793, DOI 10.1001/archsurg.142.8.793
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   JOHANNIGMAN JA, 1992, J TRAUMA, V32, P190, DOI 10.1097/00005373-199202000-00014
   Johnson JW, 2001, J TRAUMA, V51, P261, DOI 10.1097/00005373-200108000-00007
   Kirkpatrick AW, 2000, CAN J SURG, V43, P207
   Klein Y, 2004, J TRAUMA, V57, P915, DOI 10.1097/01.TA.0000136690.34310.9D
   Krishna G, 1998, AUST NZ J SURG, V68, P826, DOI 10.1111/j.1445-2197.1998.tb04696.x
   Lamme B, 2002, BJS-BRIT J SURG, V89, P1516, DOI 10.1046/j.1365-2168.2002.02293.x
   Lamme B, 2004, BJS-BRIT J SURG, V91, P1046, DOI 10.1002/bjs.4517
   Leatherman JW, 1996, AM J RESP CRIT CARE, V153, P1686, DOI 10.1164/ajrccm.153.5.8630621
   Lionetti V, 2005, CURR OPIN CRIT CARE, V11, P82, DOI 10.1097/00075198-200502000-00013
   Malangoni MA, 2000, AM SURGEON, V66, P157
   Malbrain MLNG, 2006, INTENS CARE MED, V32, P1722, DOI 10.1007/s00134-006-0349-5
   Malbrain MLNG, 2011, AM SURGEON, V77, pS6
   Malbrain MLNG, 2009, CRIT CARE MED, V37, P781, DOI 10.1097/CCM.0b013e318194c397
   Malbrain MLNG, 2004, INTENS CARE MED, V30, P822, DOI 10.1007/s00134-004-2169-9
   MATHIEU D, 1991, CRIT CARE MED, V19, P1352, DOI 10.1097/00003246-199111000-00008
   Maxwell RA, 1999, J TRAUMA, V47, P995, DOI 10.1097/00005373-199912000-00001
   Mayberry JC, 2000, CRIT CARE CLIN, V16, P151, DOI 10.1016/S0749-0704(05)70102-0
   Mayberry JC, 1997, ARCH SURG-CHICAGO, V132, P957
   MAYBERRY JC, 1997, ARCH SURG-CHICAGO, V132, P961
   McKibbin B, 2003, NUTRITION, V19, P563, DOI 10.1016/S0899-9007(02)01105-X
   Meldrum DR, 1997, AM J SURG, V174, P667, DOI 10.1016/S0002-9610(97)00201-8
   Miller PR, 2002, J TRAUMA, V53, P843, DOI 10.1097/00005373-200211000-00007
   Moore EE, 1996, AM J SURG, V172, P405, DOI 10.1016/S0002-9610(96)00216-4
   Moore EE, 1998, WORLD J SURG, V22, P1184, DOI 10.1007/s002689900542
   MOORE FA, 1992, ANN SURG, V216, P172, DOI 10.1097/00000658-199208000-00008
   Morris JA, 2006, J TRAUMA, V60, P1165, DOI 10.1097/01.ta.0000220384.04978.3b
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Murray MJ, 2002, CRIT CARE MED, V30, P142, DOI 10.1097/00003246-200201000-00021
   Norris PR, 2006, ANN SURG, V243, P804, DOI 10.1097/01.sla.0000219642.92637.fd
   OBEID F, 1995, ARCH SURG-CHICAGO, V130, P544
   Ochsner MG, 2003, AM SURGEON, V69, P742
   Offner PJ, 2001, ARCH SURG-CHICAGO, V136, P676, DOI 10.1001/archsurg.136.6.676
   Opmeer BC, 2010, CRIT CARE, V14, DOI 10.1186/cc9032
   Ouellet JF, 2011, AM SURGEON, V77, pS51
   Pape HC, 2002, AM J SURG, V183, P622, DOI 10.1016/S0002-9610(02)00865-6
   Perel P, 2007, COCHRANE DB SYST REV, V4
   Polderman KH, 2009, CRIT CARE MED, V37, pS186, DOI 10.1097/CCM.0b013e3181aa5241
   Porter JM, 1997, J TRAUMA, V42, P559, DOI 10.1097/00005373-199703000-00031
   RADY MY, 1992, RESUSCITATION, V23, P227, DOI 10.1016/0300-9572(92)90006-X
   RADY MY, 1994, ANN EMERG MED, V24, P685, DOI 10.1016/S0196-0644(94)70279-9
   Rady MY, 1996, AM J EMERG MED, V14, P218, DOI 10.1016/S0735-6757(96)90136-9
   RAMIREZ OM, 1990, PLAST RECONSTR SURG, V86, P519, DOI 10.1097/00006534-199009000-00023
   Reilingh TSD, 2003, J AM COLL SURGEONS, V196, P32, DOI 10.1016/S1072-7515(02)01478-3
   Rhee P, 1998, J TRAUMA, V44, P313, DOI 10.1097/00005373-199802000-00014
   Rivers E, 2001, NEW ENGL J MED, V345, P1368, DOI 10.1056/NEJMoa010307
   Rodriguez ED, 2007, PLAST RECONSTR SURG, V120, P669, DOI 10.1097/01.prs.0000270303.44219.76
   ROTONDO MF, 1993, J TRAUMA, V35, P375, DOI 10.1097/00005373-199309000-00008
   Rotondo MF, 1997, SURG CLIN N AM, V77, P761, DOI 10.1016/S0039-6109(05)70582-X
   Sautner T, 1997, ARCH SURG-CHICAGO, V132, P250
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   SCHEIN M, 1991, WORLD J SURG, V15, P537, DOI 10.1007/BF01675658
   SCHEIN M, 1986, BRIT J SURG, V73, P369, DOI 10.1002/bjs.1800730514
   Schierhout G, 1998, BMJ-BRIT MED J, V316, P961, DOI 10.1136/bmj.316.7136.961
   SCHREIBER TC, 2005, CONT CRIT CARE, V3, P1
   Seekamp A, 1999, J TRAUMA, V47, P673, DOI 10.1097/00005373-199910000-00011
   Sharshar T, 2003, CRIT CARE MED, V31, P1752, DOI 10.1097/01.CCM.0000063046.82359.4A
   Stawicki SP, 2008, INJURY, V39, P93, DOI 10.1016/j.injury.2007.06.011
   STONE HH, 1983, ANN SURG, V197, P532, DOI 10.1097/00000658-198305000-00005
   Subramaniam MH, 2002, J TRAUMA, V53, P386, DOI 10.1097/00005373-200208000-00037
   Tisherman SA, 2004, J TRAUMA, V57, P898, DOI 10.1097/01.TA.0000133577.25793.E5
   Tremblay LN, 2001, AM J SURG, V182, P670, DOI 10.1016/S0002-9610(01)00805-4
   Tsuei BJ, 2004, AM SURGEON, V70, P652
   Tyburski J, 2004, AM SURGEON, V70, P140
   Van den Berghe G, 2006, NEW ENGL J MED, V354, P449, DOI 10.1056/NEJMoa052521
   Van den Berghe G, 2001, NEW ENGL J MED, V345, P1359, DOI 10.1056/NEJMoa011300
   van Ruler O, 2007, JAMA-J AM MED ASSOC, V298, P865, DOI 10.1001/jama.298.8.865
   vanGoor H, 1997, EUR J SURG, V163, P61
   Vargo D, 2004, AM J SURG, V188, P633, DOI 10.1016/j.amjsurg.2004.08.051
   Vargo D, 2009, AM SURGEON, V75, pS1
   Vlasselaers D, 2009, LANCET, V373, P547, DOI 10.1016/S0140-6736(09)60044-1
   Wacha H, 1999, LANGENBECK ARCH SURG, V384, P24, DOI 10.1007/s004230050169
   Watters JM, 2006, J TRAUMA, V61, P300, DOI 10.1097/01.ta.0000224211.36154.44
   Weiss G, 2006, LANGENBECK ARCH SURG, V391, P473, DOI 10.1007/s00423-006-0071-3
   Wiedemann HP, 2006, NEW ENGL J MED, V354, P2564
   Winchell RJ, 2006, J TRAUMA, V60, P1173
   Wong K, 2005, INT J CLIN PRACT, V59, P1479, DOI 10.1111/j.1368-5031.2005.00658.x
   Zarzaur BL, 2008, J SURG RES, V147, P229, DOI 10.1016/j.jss.2008.03.025
NR 153
TC 47
Z9 56
U1 0
U2 12
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0039-6109
EI 1558-3171
J9 SURG CLIN N AM
JI Surg. Clin.-North Am.
PD APR
PY 2012
VL 92
IS 2
BP 243
EP +
DI 10.1016/j.suc.2012.01.006
PG 16
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 926LH
UT WOS:000302832000007
PM 22414411
DA 2026-07-24
ER

PT J
AU Kiessling, AH
   Lehmann, A
   Isgro, F
   Moritz, A
AF Kiessling, Arndt H.
   Lehmann, Andreas
   Isgro, Frank
   Moritz, Anton
TI Tremendous bleeding complication after vacuum-assisted sternal closure
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
ID CARDIAC-SURGERY; WOUND INFECTIONS; MANAGEMENT; THERAPY
AB Vacuum-assisted closure (VAC) of complex infected wounds has recently gained popularity among various surgical specialties. The system is based on the application of negative pressure by controlled suction to the wound surface. The effectiveness of the VAC System on microcirculation and the promotion of granulation tissue proliferation are proved. No contraindications for the use in deep sternal wounds in cardiac surgery are described. In our case report we illustrate a scenario were a patient developed severe bleeding from the ascending aorta by penetration of wire fragments in the vessel. We conclude that all free particles in the sternum have to be removed completely before negative pressure is used.
C1 [Kiessling, Arndt H.; Moritz, Anton] Goethe Univ Frankfurt, Dept Thorac & Cardiovasc Surg, Frankfurt, Germany.
   [Isgro, Frank] Klinikum Ludwigshafen, Dept Cardiac Surg, D-67069 Ludwigshafen, Germany.
C3 Goethe University Frankfurt; Ludwigshafen Hospital
RP Kiessling, AH (通讯作者)，Goethe Univ Frankfurt, Dept Thorac & Cardiovasc Surg, Frankfurt, Germany.
EM cardiac.surgeon@dr-kiessling.com
RI Kiessling, Arndt-H/AAI-7261-2020
OI Kiessling, Arndt-H/0000-0003-0472-755X
CR Doss M, 2002, EUR J CARDIO-THORAC, V22, P934, DOI 10.1016/S1010-7940(02)00594-8
   Graf K, 2010, EUR J CARDIO-THORAC, V37, P893, DOI 10.1016/j.ejcts.2009.10.005
   Grauhan O, 2010, INTERACT CARDIOV TH, V11, P493, DOI 10.1510/icvts.2010.238105
   Malmsjö M, 2007, PLAST RECONSTR SURG, V120, P1266, DOI 10.1097/01.prs.0000279326.84535.2d
   Reiss N, 2007, ANN THORAC SURG, V83, P2246, DOI 10.1016/j.athoracsur.2006.07.077
   Schimmer C, 2008, THORAC CARDIOV SURG, V56, P200, DOI 10.1055/s-2008-1038386
   Schimmer Christoph, 2007, Interact Cardiovasc Thorac Surg, V6, P708, DOI 10.1510/icvts.2007.164004
   Strecker T, 2007, HEART SURG FORUM, V10, pE366, DOI 10.1532/HSF98.20071079
   Wetzel-Roth W, 2004, ZBL CHIR, V129, pS7, DOI 10.1055/s-2004-822677
   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
NR 10
TC 17
Z9 21
U1 0
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD FEB 9
PY 2011
VL 6
AR 16
DI 10.1186/1749-8090-6-16
PG 3
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 725PM
UT WOS:000287657800001
PM 21306630
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Baisch, A
   Hörmann, K
   Goessler, UR
   Sauter, A
   Riedel, F
AF Baisch, A.
   Hormann, K.
   Goessler, U. R.
   Sauter, A.
   Riedel, F.
TI Vacuum-assisted closure of nonhealing wounds in head and neck
   reconstructive surgery
SO HNO
LA English
DT Article
DE vacuum sealing; vacuum therapy; wound treatment; topical negative
   pressure
ID PRESSURE; FLAP
AB Chronic wounds are characterized by slow or nonexistent wound healing. Usually their treatment is expensive. Therefore new concepts in management are of interest in order to reduce treatment time and costs. One option is vacuum sealing. The concept of topical negative pressure is not new, and many chronic nonhealing wounds could be closed successfully with the help of vacuum sealing. Until now, there has been no documented case of vacuum sealing in head and neck reconstructive surgery. Our case shows the effectiveness of a vacuum-assisted device in successful closure of a chronic nonhealing wound in this region.
C1 Univ Hals Nasen Ohren Klin, D-68135 Mannheim, Germany.
C3 Ruprecht Karls University Heidelberg
RP Riedel, F (通讯作者)，Univ Hals Nasen Ohren Klin, Theodor Kutzer Ufer, D-68135 Mannheim, Germany.
EM frank.riedel@hno.ma.uni-heidelberg.de
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Fleischmann W, 1998, CHIRURG, V69, P222, DOI 10.1007/s001040050402
   Horch RE, 2000, HEAD NECK-J SCI SPEC, V22, P513, DOI 10.1002/1097-0347(200008)22:5<513::AID-HED12>3.3.CO;2-E
   HORCH RE, 2005, EUR SURG, V55, P5
   MOCH D, 1998, KLINIKARZT, V5, P126
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Moues C M, 2005, J Wound Care, V14, P224
   PANNIERFISCHER F, 2005, HAUTARZT, V54, P1057
   Papadopoulos ON, 2005, SCAND J PLAST RECONS, V39, P158, DOI 10.1080/02844310510006213
   RAFFL AB, 1952, ANN SURG, V136, P1048, DOI 10.1097/00000658-195212000-00022
   Riedel F, 2005, IN VIVO, V19, P343
   RIEDEL F, 2006, IN PRESS AURIS NASUS
   ROSEN RG, 1966, SURG FORUM, V11, P297
   SAMES CP, 1977, BRIT MED J, V2, P1125
   SCHEITHAUER M, 2005, LARYNGO RHINO OTOL, V82, P51
   SCHERER LA, 2002, ARCH SURG-CHICAGO, V157, P950
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   SILVIS RS, 1955, ANN SURG, V142, P252, DOI 10.1097/00000658-195508000-00011
   Tautenhahn J, 2004, CHIRURG, V75, P492, DOI 10.1007/s00104-004-0844-6
   VOINCHET V, 1996, ANN CHIR PLAST ESTH, V41, P585
   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
   WILD T, 2004, ZENTRALBL CHIR, V129, P7
NR 24
TC 1
Z9 1
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0017-6192
EI 1433-0458
J9 HNO
JI HNO
PD MAY
PY 2007
VL 55
IS 5
BP 392
EP +
DI 10.1007/s00106-006-1404-9
PG 6
WC Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology
GA 166CI
UT WOS:000246354400011
PM 16614842
DA 2026-07-24
ER

PT J
AU Matthews, KJ
   Brock, E
   Cohen, SA
   Chelmow, D
AF Matthews, Kirk J.
   Brock, Ellen
   Cohen, Stephen A.
   Chelmow, David
TI Hysterectomy in Obese Patients: Special Considerations
SO CLINICAL OBSTETRICS AND GYNECOLOGY
LA English
DT Article
DE hysterectomy; obesity; complications; BMI; technique; management
ID BODY-MASS INDEX; VACUUM-ASSISTED CLOSURE; NUTRITIONAL DEFICIENCIES;
   COMPLICATIONS; RISK; FORM
AB A literature search was performed to find evidence-based practices that aid in the preoperative evaluation, intraoperative techniques, and postoperative management of the obese patient requiring hysterectomy. Complications are more frequent than in normal weight patients and are more difficult to manage. Few studies provide direct evidence with which to help guide surgical decision-making and postoperative management. However, there is sufficient evidence to support that when feasible, the vaginal route is preferable in obese patients. Techniques validated for normal weight patients like antibiotic and thromboembolism prophylaxis seem effective in obese patients, and are likely even more important.
C1 [Matthews, Kirk J.; Brock, Ellen; Cohen, Stephen A.; Chelmow, David] Virginia Commonwealth Univ, Med Ctr, Richmond, VA USA.
C3 Virginia Commonwealth University
RP Chelmow, D (通讯作者)，Virginia Commonwealth Univ, Sch Med, Richmond, VA 23284 USA.
EM dchelmow@mcvh-vcu.edu
CR Altman AD, 2011, J OBSTET GYNAECOL CA, V33, P1031, DOI 10.1016/S1701-2163(16)35052-6
   [Anonymous], 2009, OBSTET GYNECOL, V113, P1108
   [Anonymous], 2012, Cancer Facts and Figures 2012
   Argenta PA, 2002, OBSTET GYNECOL, V99, P497, DOI 10.1016/S0029-7844(01)01752-5
   Brezina PR, 2009, JSLS-J SOC LAPAROEND, V13, P358
   Choban PS, 1997, J AM COLL SURGEONS, V185, P593, DOI 10.1016/S1072-7515(97)00109-9
   El-Nashar SA, 2010, AM J OBSTET GYNECOL, V202
   Flynn M, 2006, AM J OBSTET GYNECOL, V195, P955, DOI 10.1016/j.ajog.2006.02.020
   Gallup DC, 1996, AM J OBSTET GYNECOL, V175, P358, DOI 10.1016/S0002-9378(96)70146-1
   Gould C, 2012, J MINIM INVAS GYN, V19, P465, DOI 10.1016/j.jmig.2012.03.014
   Guyatt GH, 2012, CHEST, V141, p7S, DOI 10.1378/chest.1412S3
   Harmanli O, 2010, J WOMENS HEALTH, V19, P1915, DOI 10.1089/jwh.2010.2032
   Isik-Akbay EF, 2004, OBSTET GYNECOL, V104, P710, DOI 10.1097/01.AOG.0000140685.30899.24
   Kaidar-Person O, 2008, OBES SURG, V18, P1028, DOI 10.1007/s11695-007-9350-5
   Kaidar-Person O, 2008, OBES SURG, V18, P870, DOI 10.1007/s11695-007-9349-y
   Laughlin SK, 2010, SEMIN REPROD MED, V28, P203, DOI 10.1055/s-0030-1251477
   Leitzmann MF, 2009, CANCER, V115, P812, DOI 10.1002/cncr.24086
   Levi J., 2012, F FAT OBESITY THREAT
   Nawfal AK, 2011, J MINIM INVAS GYN, V18, P328, DOI 10.1016/j.jmig.2011.01.009
   Nguyen NT, 2005, ANN SURG, V241, P219, DOI 10.1097/01.sla.0000151791.93571.70
   Nieboer TE, 2009, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD003677.pub4, 10.1002/14651858.CD003677.pub5]
   Osler M, 2011, HUM REPROD, V26, P1512, DOI 10.1093/humrep/der060
   Poirier P, 2009, CIRCULATION, V120, P86, DOI 10.1161/CIRCULATIONAHA.109.192575
   Prevention of DVT and Pulmonary Embolism, 2007, OBSTET GYNECOL, V100, P429
   Rasmussen KL, 2004, ACTA OBSTET GYN SCAN, V83, P85, DOI 10.1111/j.1600-0412.2004.00285.x
   Schimp VL, 2004, GYNECOL ONCOL, V92, P586, DOI 10.1016/j.ygyno.2003.10.055
   Slim K, 2004, BRIT J SURG, V91, P1125, DOI 10.1002/bjs.4651
   Walsh C, 2009, OBSTET GYNECOL, V113, P411, DOI 10.1097/AOG.0b013e3181945625
   Wells T, 2011, INT J GYNECOL CANCER, V21, P1135, DOI 10.1097/IGC.0b013e31821778c4
NR 29
TC 11
Z9 17
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0009-9201
EI 1532-5520
J9 CLIN OBSTET GYNECOL
JI Clin. Obstet. Gynecol.
PD MAR
PY 2014
VL 57
IS 1
BP 106
EP 114
DI 10.1097/GRF.0000000000000005
PG 9
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA AJ8RI
UT WOS:000337974200009
PM 24335622
DA 2026-07-24
ER

PT J
AU Kreis, BE
   van Otterloo, JCAD
   Kreis, RW
AF Kreis, Barbara Elize
   van Otterloo, Johan Coenraad Alexander de Mol
   Kreis, Robert Walter
TI Open abdomen management: A review of its history and a proposed
   management algorithm
SO MEDICAL SCIENCE MONITOR
LA English
DT Review
DE open abdomen; abdominal trauma; septic abdomen; damage control surgery;
   temporary abdominal closure
ID TEMPORARY ABDOMINAL CLOSURE; VACUUM-ASSISTED CLOSURE; TOPICAL
   NEGATIVE-PRESSURE; DAMAGE-CONTROL; PLANNED RELAPAROTOMY; COMPARTMENT
   SYNDROME; FASCIAL CLOSURE; PERITONEAL-CAVITY; WOUND CLOSURE;
   INTRAABDOMINAL INFECTION
AB In this review we look into the historical development of open abdomen management. Its indication has spread in 70 years from intra-abdominal sepsis to damage control surgery and abdominal compartment syndrome. Different temporary abdominal closure techniques are essential to benefit the potential advantages of open abdomen management. Here, we discuss the different techniques and provide a new treatment strategy, based on available evidence, to facilitate more consistent decision making and further research on this complicated surgical topic.
C1 [Kreis, Barbara Elize; van Otterloo, Johan Coenraad Alexander de Mol] Med Ctr Haaglanden, The Hague, Netherlands.
   [Kreis, Robert Walter] Rode Kruis Ziekenhuis, Beverwijk, Netherlands.
C3 Haaglanden Medical Center
RP Kreis, BE (通讯作者)，Med Ctr Haaglanden, The Hague, Netherlands.
EM barbarakreis@hotmail.com
CR Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
   Adkins AL, 2004, AM SURGEON, V70, P137
   Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
   ANDERSON ED, 1983, AM J SURG, V145, P131, DOI 10.1016/0002-9610(83)90179-4
   [Anonymous], 1986, LANCET, V2, P138
   APRAHAMIAN C, 1990, J TRAUMA, V30, P719, DOI 10.1097/00005373-199006000-00011
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   Björck M, 2009, WORLD J SURG, V33, P1154, DOI 10.1007/s00268-009-9996-3
   Boermeester MA, 2007, BRIT J SURG, V94, P1317, DOI 10.1002/bjs.6041
   Borráez Oswaldo Alfonso, 2008, rev. colomb. cir., V23, P204
   Bosscha K, 2000, EUR J SURG, V166, P44
   BROCK WB, 1995, AM SURGEON, V61, P30
   BROOME A, 1983, WORLD J SURG, V7, P792, DOI 10.1007/BF01655223
   Cheatham ML, 2010, CRIT CARE MED, V38, P402, DOI 10.1097/CCM.0b013e3181b9e9b1
   Cheatham ML, 2004, J TRAUMA, V56, P237, DOI 10.1097/01.TA.0000109858.55483.86
   CHRISTOU NV, 1993, ARCH SURG-CHICAGO, V128, P193
   Cipolla J, 2005, AM SURGEON, V71, P202
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   CUESTA MA, 1991, WORLD J SURG, V15, P74, DOI 10.1007/BF01658968
   Diaz JJ, 2010, J TRAUMA, V68, P1425, DOI 10.1097/TA.0b013e3181da0da5
   Duchesne JC, 2009, AM SURGEON, V75, P1193
   DUFF JH, 1981, SURGERY, V90, P774
   FAYMAN MS, 1990, S AFR J SURG, V28, P62
   Feliciano D, 2008, TRAUMA, P860
   Finlay IG, 2004, BJS-BRIT J SURG, V91, P83, DOI 10.1002/bjs.4434
   Gäddnäs F, 2007, SCAND J SURG, V96, P301
   GARCIASABRIDO JL, 1988, ARCH SURG-CHICAGO, V123, P152
   Garner GB, 2001, AM J SURG, V182, P630, DOI 10.1016/S0002-9610(01)00786-3
   Ghimenton F, 2000, BRIT J SURG, V87, P106, DOI 10.1046/j.1365-2168.2000.01337.x
   Goodman MD, 2010, SURGERY, V148, P799, DOI 10.1016/j.surg.2010.07.035
   Gracias VH, 2002, ARCH SURG-CHICAGO, V137, P1298, DOI 10.1001/archsurg.137.11.1298
   Hadeed JG, 2007, AM SURGEON, V73, P10
   HAU T, 1995, ARCH SURG-CHICAGO, V130, P1193
   HEDDERICH GS, 1986, SURGERY, V99, P399
   HOWARD CA, 1989, CRIT CARE MED, V17, P586, DOI 10.1097/00003246-198906000-00022
   Ivatury RR, 2007, ACTA CLIN BELG, V62, P206, DOI 10.1179/acb.2007.62.s1.027
   IVATURY RR, 1989, CRIT CARE MED, V17, P511, DOI 10.1097/00003246-198906000-00005
   Jansen JO, 2007, BRIT J SURG, V94, P789, DOI 10.1002/bjs.5922
   Joglar F, 2010, J SURG RES, V162, P274, DOI 10.1016/j.jss.2009.03.031
   Kaplan M, 2005, WOUNDS S
   Karmali S, 2006, J TRAUMA, V60, P287, DOI 10.1097/01.ta.0000203579.62446.75
   Kiewiet JJ, 2009, NED TIJDSCHR GENEES, V153, pA386
   Kirkpatrick AW, 2006, J TRAUMA, V60, P279, DOI 10.1097/01.ta.0000205638.26798.dc
   Kirshtein B, 2007, AM SURGEON, V73, P249
   Kritayakirana Kritaya, 2010, J Emerg Trauma Shock, V3, P118, DOI 10.4103/0974-2700.62106
   Lamme B, 2002, BJS-BRIT J SURG, V89, P1516, DOI 10.1046/j.1365-2168.2002.02293.x
   Lamme B, 2004, BJS-BRIT J SURG, V91, P1046, DOI 10.1002/bjs.4517
   Losanoff JE, 2002, J AM COLL SURGEONS, V195, P105, DOI 10.1016/S1072-7515(02)01149-3
   MASTBOOM WJB, 1989, ARCH SURG-CHICAGO, V124, P689
   Mattox KL, 1997, SURG CLIN N AM, V77, P753, DOI 10.1016/S0039-6109(05)70581-8
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Miller PR, 2002, J TRAUMA, V53, P843, DOI 10.1097/00005373-200211000-00007
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   MUGHAL MM, 1986, BRIT J SURG, V73, P253, DOI 10.1002/bjs.1800730405
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   Ogilvie WH, 1940, LANCET, V2, P253
   OGILVIE WH, 1945, BMJ-BRIT MED J, V1, P619, DOI 10.1136/bmj.1.4400.619
   Olejnik J, 2007, BRATISL MED J, V108, P320
   Padalino P, 2010, SURG INFECT, V11, P523, DOI 10.1089/sur.2010.042
   PENNINCKX FM, 1983, WORLD J SURG, V7, P762, DOI 10.1007/BF01655218
   Perathoner A, 2010, INT J COLORECTAL DIS, V25, P767, DOI 10.1007/s00384-010-0887-8
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   Petersson U, 2007, WORLD J SURG, V31, P2133, DOI 10.1007/s00268-007-9222-0
   Pliakos I, 2010, SURGERY, V148, P947, DOI 10.1016/j.surg.2010.01.021
   Reimer MW, 2008, CAN J SURG, V51, P209
   Robledo Felipe A, 2007, Surg Infect (Larchmt), V8, P63, DOI 10.1089/sur.2006.8.016
   ROTONDO MF, 1993, J TRAUMA, V35, P375, DOI 10.1097/00005373-199309000-00008
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   Schein M, 2002, LANGENBECK ARCH SURG, V387, P1, DOI 10.1007/s00423-002-0276-z
   SCHEIN M, 1991, WORLD J SURG, V15, P537, DOI 10.1007/BF01675658
   SCHEIN M, 1988, BRIT J SURG, V75, P173, DOI 10.1002/bjs.1800750230
   SCHEIN M, 1986, BRIT J SURG, V73, P369, DOI 10.1002/bjs.1800730514
   SCHEIN M, 1986, SURG GYNECOL OBSTET, V163, P587
   Scott BG, 2005, SCAND J SURG, V94, P9, DOI 10.1177/145749690509400104
   Scott BG, 2006, J TRAUMA, V60, P17, DOI 10.1097/01.ta.0000200861.96568.bb
   Smith LA, 1997, AM SURGEON, V63, P1102
   Sokmen S, 2002, Hernia, V6, P124
   Stawicki SP, 2008, INJURY, V39, P93, DOI 10.1016/j.injury.2007.06.011
   STEINBERG D, 1979, AM J SURG, V137, P216, DOI 10.1016/0002-9610(79)90148-X
   Stevens P, 2009, INT WOUND J, V6, P259, DOI 10.1111/j.1742-481X.2009.00614.x
   Sugrue M, 2007, ACTA CLIN BELG, V62, P210, DOI 10.1179/acb.2007.62.s1.028
   Sugrue M, 1998, J TRAUMA, V45, P914, DOI 10.1097/00005373-199811000-00013
   Sugrue M, 2009, WORLD J SURG, V33, P1123, DOI 10.1007/s00268-009-0040-4
   TEICHMANN W, 1986, ARCH SURG-CHICAGO, V121, P147
   Teixeira PGR, 2008, AM SURGEON, V74, P891
   Tsuei BJ, 2004, AM SURGEON, V70, P652
   van As AB, 2007, ACTA CLIN BELG, V62, P215, DOI 10.1179/acb.2007.62.s1.029
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   van Ruler O, 2007, JAMA-J AM MED ASSOC, V298, P865, DOI 10.1001/jama.298.8.865
   van Ruler O, 2007, CRIT CARE MED, V35, P468, DOI 10.1097/01.CCM.0000253399.03545.2D
   van Wessem KJP, 2010, ACTA CHIR BELG, V110, P499, DOI 10.1080/00015458.2010.11680664
   Vargo D, 2009, AM SURGEON, V75, pS1
   Vertrees A, 2008, J AM COLL SURGEONS, V207, P801, DOI 10.1016/j.jamcollsurg.2008.08.014
   VOYLES CR, 1981, ANN SURG, V194, P219, DOI 10.1097/00000658-198108000-00017
   Waibel BH, 2010, CRIT CARE MED, V38, pS421, DOI 10.1097/CCM.0b013e3181ec5cbe
   WITTMANN DH, 1990, WORLD J SURG, V14, P218, DOI 10.1007/BF01664876
   Wittmann DH, 1998, INFECTION, V26, P335, DOI 10.1007/BF02962267
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
NR 99
TC 40
Z9 43
U1 0
U2 6
PU INT SCIENTIFIC INFORMATION, INC
PI MELVILLE
PA 150 BROADHOLLOW RD, STE 114, MELVILLE, NY 11747 USA
SN 1643-3750
J9 MED SCI MONITOR
JI Med. Sci. Monitor
PD JUL 3
PY 2013
VL 19
BP S24
EP S33
PG 10
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA 176DS
UT WOS:000321284300001
DA 2026-07-24
ER

PT J
AU Matzi, V
   Lindenmann, J
   Porubsky, C
   Neuboeck, N
   Maier, A
   Smolle-Juettner, FM
AF Matzi, Veronika
   Lindenmann, Joerg
   Porubsky, Christian
   Neuboeck, Nicole
   Maier, Alfred
   Smolle-Juettner, Frevja Maria
TI Intrathoracic insertion of the VAC device in a case of pleural empyema
   20 years after pneumonectorny
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID ASSISTED CLOSURE; WOUND CONTROL; MANAGEMENT
AB We report a 72-year-old man suffering from pleural empyema after pneumonectomy due to nonsmall cell lung cancer 20 years previously. Insufficiency of the bronchial stump was ruled out by bronchoscopy and bronchography. Thoracic computed tomographic scan of the thorax detected an abscess located in the subcutaneous tissue of the right ventrolateral chest wall originating from severe pyogenic osteomyelitis of the fifth and sixth ribs. Our surgical management included partial resection of the chest wall followed by insertion of the vacuum-assisted closure system into the thoracic cavity. The patient fully recovered and was discharged on postoperative day 32.
C1 Med Univ Graz, Dept Gen Surg, Div Thorac & Hyperbar Surg, A-8036 Graz, Austria.
C3 Medical University of Graz
RP Lindenmann, J (通讯作者)，Med Univ Graz, Dept Gen Surg, Div Thorac & Hyperbar Surg, Auenbruggerpl 29, A-8036 Graz, Austria.
EM jo.lindenmann@meduni-graz.at
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Ditterich D, 2006, ZBL CHIR, V131, pS133, DOI 10.1055/s-2006-921499
   Massera F, 2006, ANN THORAC SURG, V82, P288, DOI 10.1016/j.athoracsur.2005.11.046
   Matzi V, 2006, ZBL CHIR, V131, pS139, DOI 10.1055/s-2006-921474
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Robinson S., 1915, COLLECTED PAPERS MAY, V7, P618
   Varker KA, 2006, ANN THORAC SURG, V81, P723, DOI 10.1016/j.athoracsur.2004.10.040
NR 7
TC 12
Z9 15
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD NOV
PY 2007
VL 84
IS 5
BP 1762
EP 1764
DI 10.1016/j.athoracsur.2007.05.052
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 229DF
UT WOS:000250782500060
PM 17954112
OA Bronze
DA 2026-07-24
ER

PT J
AU Hynes, PJ
   Earley, MJ
   Lawlor, D
AF Hynes, PJ
   Earley, MJ
   Lawlor, D
TI Split-thickness skin grafts and negative-pressure dressings in the
   treatment of axillary hidradenitis suppurativa
SO BRITISH JOURNAL OF PLASTIC SURGERY
LA English
DT Article
DE axillary skin defect; split-thickness skin graft; negative-pressure
   dressing; hidradenitis suppurativa
ID VACUUM-ASSISTED CLOSURE; SURGICAL-TREATMENT; WOUND CONTROL; FLAP
AB Although a number of different reconstructive techniques have been described for the treatment of axillary skin defects, split-thickness skin grafting continues to be the most common surgical modality. Here, we present our recent experience of using split-thickness skin grafts together with negative-pressure dressings for the management of defects following wide surgical excision of severe hidradenitis suppurativa. This technique ensures complete skin-graft take whilst allowing full shoulder mobility, thereby minimising the undesirable sequelae associated with split-thickness skin grafting alone. (C) 2002 The British Association of Plastic Surgeons.
C1 Mater Misericordiae Hosp, Dept Plast & Reconstruct Surg, Dublin 7, Ireland.
C3 Mater Misericordiae University Hospital; University College Dublin
RP Hynes, PJ (通讯作者)，Mater Misericordiae Hosp, Dept Plast & Reconstruct Surg, Eccles St, Dublin 7, Ireland.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BANERJEE AK, 1992, BRIT J SURG, V79, P863, DOI 10.1002/bjs.1800790905
   ELLIOT D, 1992, BRIT J PLAST SURG, V45, P101, DOI 10.1016/0007-1226(92)90166-U
   Endo Y, 1998, BRIT J DERMATOL, V139, P906
   Jemec GBE, 1996, CLIN EXP DERMATOL, V21, P419, DOI 10.1111/j.1365-2230.1996.tb00145.x
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   RADCLIFFE KW, 1991, GENITOURIN MED, V67, P58
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   Schwabegger AH, 2000, BRIT J PLAST SURG, V53, P676, DOI 10.1054/bjps.2000.3443
   Soldin MG, 2000, BRIT J PLAST SURG, V53, P434, DOI 10.1054/bjps.1999.3285
   Von der Werth JM, 2000, BRIT J DERMATOL, V142, P947, DOI 10.1046/j.1365-2133.2000.03476.x
   Von der Werth JM, 2001, BRIT J DERMATOL, V144, P809, DOI 10.1046/j.1365-2133.2001.04137.x
NR 12
TC 40
Z9 43
U1 0
U2 1
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE,
   LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0007-1226
J9 BRIT J PLAST SURG
JI Br. J. Plast. Surg.
PD SEP
PY 2002
VL 55
IS 6
BP 507
EP 509
DI 10.1054/bjps.2002.3899
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 601RW
UT WOS:000178462600009
PM 12479426
DA 2026-07-24
ER

PT J
AU Sposato, G
   Molea, G
   Di Caprio, G
   Scioli, M
   La Rusca, I
   Ziccardi, P
AF Sposato, G
   Molea, G
   Di Caprio, G
   Scioli, M
   La Rusca, I
   Ziccardi, P
TI Ambulant vacuum-assisted closure of skin-graft dressing in the lower
   limbs using a portable mini-VAC device
SO BRITISH JOURNAL OF PLASTIC SURGERY
LA English
DT Article
DE vacuum-assisted wound closure; lower limb; skin graft
AB A skin graft may fail to adhere to the recipient site because of fluid collecting between the graft and the area being treated. We have devised a simple procedure, consisting of a vacuum-sealed dressing, to fix skin grafts on the lower limbs. A fully portable, battery-operated aspirator continuously draws secretions through a vacuum-sealed dressing, preventing accumulation of fluid underneath the graft. Patients are not confined to bed, thus reducing nursing time. The procedure was applied successfully in seven out of nine patients treated for ulcers of the lower limbs. (C) 2001 The British Association of Plastic Surgeons.
C1 Univ Naples Federico II, Inst Plast & Reconstruct Surg, Naples, Italy.
   Salvatore Maugeri Fdn, Inst Care & Sci Res Rehabil, Inst Telese Terme Benevento, Telese Terme, Benevento, Italy.
C3 University of Naples Federico II; Istituti Clinici Scientifici Maugeri
   IRCCS
RP Molea, G (通讯作者)，Univ Naples Federico II, Inst Plast & Reconstruct Surg, Via S Pansini 5, Naples, Italy.
RI Di Caprio, Giovanni/E-1377-2019; scioli, michelina/E-1312-2019
OI Di Caprio, Giovanni/0000-0002-4001-8876; scioli,
   michelina/0000-0002-1183-7450
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Balakrishnan Chenicheri, 1994, Journal of Burn Care and Rehabilitation, V15, P432, DOI 10.1097/00004630-199409000-00010
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Collier M, 1997, Nurs Times, V93, P32
   Deva A K, 1997, J Wound Care, V6, P311
   Francis A, 1998, Nurs Stand, V12, P41
   KOLDAS T, 1992, ANN PLAS SURG, V28, P386, DOI 10.1097/00000637-199204000-00017
   Morykwas M J, 1997, J South Orthop Assoc, V6, P279
   Ratner D, 1998, DERMATOL CLIN, V16, P75, DOI 10.1016/S0733-8635(05)70488-5
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   Wolf Y, 1998, ANN PLAS SURG, V40, P149, DOI 10.1097/00000637-199802000-00008
NR 11
TC 50
Z9 61
U1 0
U2 4
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE,
   LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0007-1226
J9 BRIT J PLAST SURG
JI Br. J. Plast. Surg.
PD APR
PY 2001
VL 54
IS 3
BP 235
EP 237
DI 10.1054/bjps.2000.3537
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 419KE
UT WOS:000167947200012
PM 11254417
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Romero, P
   Kessler, M
   Springer, W
   Holland-Cunz, S
AF Romero, P.
   Kessler, M.
   Springer, W.
   Holland-Cunz, S.
TI Combined IntegraA® and vacuum-assisted therapy in premature infants - A
   case report of secondary wound closure for soft tissue necrosis of the
   lower extremity
SO MONATSSCHRIFT KINDERHEILKUNDE
LA German
DT Article
DE Artificial skin; Integra (R); Soft tissue necrosis; Vacuum-assisted
   closure; Children
ID BURN INJURY
AB The authors report the case of a premature infant who developed large-area skin and soft tissue necrosis as the result of a circulatory disorder in the right leg after thrombosis of the right femoral artery. After necrosectomy and simultaneous IntegraA (R) and vacuum-assisted therapy, split-thickness skin grafts were successfully used to cover the soft tissue defect. The authors report, for the first time, the difficulties involved and their experience with secondary wound closure in hypoperfused soft tissue in a premature infant.
C1 [Romero, P.; Kessler, M.; Holland-Cunz, S.] Univ Klinikum Heidelberg, Chirurg Klin, Sekt Kinderchirurg, D-69120 Heidelberg, Germany.
   [Springer, W.] Univ Klinikum Heidelberg, Zentrum Kinder & Jugendmed, Abt Padiatr Kardiol, D-69120 Heidelberg, Germany.
C3 Ruprecht Karls University Heidelberg; Ruprecht Karls University
   Heidelberg
RP Romero, P (通讯作者)，Univ Klinikum Heidelberg, Chirurg Klin, Sekt Kinderchirurg, Neuenheimer Feld 110, D-69120 Heidelberg, Germany.
EM Philipp.Romero@med.uni-heidelberg.de
CR Berger A, 2000, CHIRURG, V71, P558, DOI 10.1007/s001040050856
   BURKE JF, 1981, ANN SURG, V194, P413, DOI 10.1097/00000658-198110000-00005
   GROSSE MP, 2008, THESIS U REGENSBURG
   Khan MR, 2007, EUR J PLAST SURG, V30, P101, DOI 10.1007/s00238-007-0160-8
   Lee LF, 2008, PLAST RECONSTR SURG, V121, P1256, DOI 10.1097/01.prs.0000304237.54236.66
   Martinez L, 2002, Cir Pediatr, V15, P97
   Rennekampff HO, 2009, UNFALLCHIRURG, V112, P543, DOI 10.1007/s00113-009-1655-5
   Schneider J, 2009, BURNS, V35, P51, DOI 10.1016/j.burns.2008.07.018
   Stone H A, 1993, J Foot Ankle Surg, V32, P232
NR 9
TC 0
Z9 0
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0026-9298
EI 1433-0474
J9 MONATSSCHR KINDERH
JI Mon.schr. Kinderheilkd.
PD APR
PY 2010
VL 158
IS 4
BP 384
EP 387
DI 10.1007/s00112-009-2145-0
PG 4
WC Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics
GA 584AX
UT WOS:000276723500014
DA 2026-07-24
ER

PT J
AU Huang, JJ
   Ren, JA
   Wang, GF
   Li, ZA
   Wu, XW
   Ren, HJ
   Liu, S
AF Huang, Jin-Jian
   Ren, Jian-An
   Wang, Ge-Fei
   Li, Zong-An
   Wu, Xiu-Wen
   Ren, Hua-Jian
   Liu, Song
TI 3D-printed "fistula stent" designed for management of enterocutaneous
   fistula: An advanced strategy
SO WORLD JOURNAL OF GASTROENTEROLOGY
LA English
DT Article
DE Enterocutaneous fistula; 3D printing; Open abdomen; Isolation technique
ID ENTEROATMOSPHERIC FISTULA
AB Enterocutaneous fistulas (ECFs) are great challenges during the open abdomen. The loss of digestive juice, water-electrolyte imbalance and malnutrition are intractable issues during management of ECF. Techniques such as "fistula patch" and vacuum-assisted closure therapy have been applied to prevent contamination of open abdominal wounds by intestinal fistula drainage. However, failures are encountered due to high-output fistula and anatomical complexity. Here, we report 3D-printed patient-personalized fistula stent for ECF treatment based on 3D reconstruction of the fistula image. Subsequent follow-up demonstrated that this stent was well-implanted and effective to reduce the volume of enteric fistula effluent.
C1 [Huang, Jin-Jian; Ren, Jian-An; Wang, Ge-Fei; Wu, Xiu-Wen; Ren, Hua-Jian] Jinling Hosp, Dept Surg, 305 East Zhongshan Rd, Nanjing 210002, Jiangsu, Peoples R China.
   [Huang, Jin-Jian] Southeast Univ, Sch Med, Nanjing 210009, Jiangsu, Peoples R China.
   [Li, Zong-An] Nanjing Normal Univ, NARI Sch Elect & Automat Engn, Nanjing 210042, Jiangsu, Peoples R China.
   [Liu, Song] Nanjing Drum Tower Hosp, Dept Gen Surg, Nanjing 210008, Jiangsu, Peoples R China.
C3 Southeast University - China; Nanjing Normal University; Nanjing
   University
RP Ren, JA (通讯作者)，Jinling Hosp, Dept Surg, 305 East Zhongshan Rd, Nanjing 210002, Jiangsu, Peoples R China.
EM jiananr@gmail.com
RI ; Li, Zongan/ABF-1785-2020; Liu, Song/GMW-4362-2022; Wu,
   Xiuwen/AEO-0814-2022
OI Huang, Jinjian/0000-0002-8951-8935; Li, Zongan/0000-0002-3580-5891; Wu,
   Xiuwen/0000-0002-3813-3867
FU National Natural Science Foundation of China [81571881]
FX Supported by the National Natural Science Foundation of China, No.
   81571881.
CR Bobkiewicz A, 2017, INT WOUND J, V14, P255, DOI 10.1111/iwj.12597
   Di Saverio S, 2016, LANGENBECK ARCH SURG, V401, P1, DOI 10.1007/s00423-015-1370-3
   Ortiz LA, 2017, NUTR CLIN PRACT, V32, P508, DOI 10.1177/0884533617701402
   Papavramidis ST, 2001, OBES SURG, V11, P766, DOI 10.1381/09608920160558759
   Rebibo L, 2017, ENDOSCOPY, V49, pE35, DOI 10.1055/s-0042-121489
   Santerre JP, 2005, BIOMATERIALS, V26, P7457, DOI 10.1016/j.biomaterials.2005.05.079
   Schecter WP, 2009, J AM COLL SURGEONS, V209, P484, DOI 10.1016/j.jamcollsurg.2009.05.025
   Wang GF, 2013, J TRAUMA ACUTE CARE, V74, P1175, DOI 10.1097/TA.0b013e318282705e
   Yetisir F, 2017, HERNIA, V21, P809, DOI 10.1007/s10029-017-1614-y
   Zhang SW, 2016, ACS APPL MATER INTER, V8, P13242, DOI 10.1021/acsami.6b01432
NR 10
TC 45
Z9 54
U1 1
U2 47
PU BAISHIDENG PUBLISHING GROUP INC
PI PLEASANTON
PA 8226 REGENCY DR, PLEASANTON, CA 94588 USA
SN 1007-9327
EI 2219-2840
J9 WORLD J GASTROENTERO
JI World J. Gastroenterol.
PD NOV 7
PY 2017
VL 23
IS 41
BP 7489
EP 7494
DI 10.3748/wjg.v23.i41.7489
PG 6
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA FL5UZ
UT WOS:000414312500015
PM 29151703
OA hybrid
DA 2026-07-24
ER

PT J
AU Ruta, D
   Ozer, K
AF Ruta, David
   Ozer, Kagan
TI Open Fractures of the Hand with Soft Tissue Loss
SO HAND CLINICS
LA English
DT Article
DE Antibiotics; Flap; Fracture; Graft; Open; Primary; Reconstruction;
   Tissue
ID VACUUM-ASSISTED CLOSURE; DERMAL REGENERATION TEMPLATE; POSTERIOR
   INTEROSSEOUS FLAP; NEGATIVE-PRESSURE THERAPY; THICKNESS SKIN-GRAFTS;
   DONOR SITE MORBIDITY; ARTERY PERFORATOR FLAP; RADIAL FOREARM FLAP; FREE
   FASCIAL FLAP; LATERAL ARM FLAP
AB The evaluation, initial treatment, and definitive reconstruction of open fractures of the hand with associated soft tissue loss are reviewed. Specific attention is given to the literature on open fracture antibiotic prophylaxis in the hand; the timing of bone and soft tissue reconstruction; and options for soft tissue coverage, including local, regional, and distant tissue transfer. Factors that have shown association with outcomes in these injuries are also discussed, and the authors' preferred management is summarized.
C1 [Ruta, David; Ozer, Kagan] Univ Michigan, Dept Orthopaed Surg, Ann Arbor, MI 48103 USA.
C3 University of Michigan System; University of Michigan
RP Ozer, K (通讯作者)，Univ Michigan, Dept Orthopaed Surg, 2098 South Main St, Ann Arbor, MI 48103 USA.
EM kozer@umich.edu
OI Ozer, Kagan/0000-0001-7397-3696
CR Adani R, 2003, ANN PLAS SURG, V51, P564, DOI 10.1097/01.sap.0000095648.33602.d6
   Al-Qattan MM, 2001, J HAND SURG-AM, V26A, P1116, DOI 10.1053/jhsu.2001.28758
   ALLEN RJ, 1994, ANN PLAS SURG, V32, P32, DOI 10.1097/00000637-199401000-00007
   Anastakis DJ, 2011, GREENS OPERATIVE HAN, P1757
   Askari M, 2011, PLAST RECONSTR SURG, V127, P1593, DOI 10.1097/PRS.0b013e31820a6511
   Azzena B, 2010, J HAND SURG-AM, V35A, P2057, DOI 10.1016/j.jhsa.2010.08.026
   BAEK SM, 1992, J RECONSTR MICROSURG, V8, P455, DOI 10.1055/s-2007-1006730
   Baker PA, 2007, J PLAST RECONSTR AES, V60, P828, DOI 10.1016/j.bjps.2007.03.001
   Bannasch H, 2008, MICROSURG, V28, P412, DOI 10.1002/micr.20512
   BECKER C, 1988, Handchirurgie Mikrochirurgie Plastische Chirurgie, V20, P180
   Biswas G, 2001, PLAST RECONSTR SURG, V108, P1639, DOI 10.1097/00006534-200111000-00031
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   BRENT B, 1985, PLAST RECONSTR SURG, V76, P177, DOI 10.1097/00006534-198508000-00001
   BURKE JF, 1961, SURGERY, V50, P161
   Capo John T, 2011, Am J Orthop (Belle Mead NJ), V40, pE243
   Carothers JT, 2005, J HAND SURG-AM, V30A, P1322, DOI 10.1016/j.jhsa.2005.08.001
   Carty MJ, 2010, PLAST RECONSTR SURG, V125, P953, DOI 10.1097/PRS.0b013e3181cc964c
   Chai Y M, 2001, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V15, P217
   Chang SC, 2004, ANN PLAS SURG, V53, P449, DOI 10.1097/01.sap.0000137134.15728.dd
   Chang SCN, 1996, MICROSURG, V17, P136
   Chang SM, 2003, MICROSURG, V23, P328, DOI 10.1002/micr.10155
   Chappell JE, 1999, ANN PLAS SURG, V42, P418, DOI 10.1097/00000637-199904000-00012
   Chen C, 2010, J HAND SURG-AM, V35A, P1663, DOI 10.1016/j.jhsa.2010.06.030
   Chen SG, 2012, INT J BURNS TRAUMA, V2, P105
   Choupina M, 2004, BRIT J PLAST SURG, V57, P465, DOI 10.1016/j.bjps.2003.12.007
   CHOW SP, 1991, J HAND SURG-BRIT EUR, V16B, P137, DOI 10.1016/0266-7681(91)90162-H
   Dantzer E, 2003, BRIT J PLAST SURG, V56, P764, DOI 10.1016/S0007-1226(03)00366-7
   Davis WJ, 2011, J HAND MICROSURG, V3, P18, DOI 10.1007/s12593-011-0036-9
   Deal DN, 2011, J RECONSTR MICROSURG, V27, P133, DOI 10.1055/s-0030-1268852
   Del Piñal F, 2006, J HAND SURG-BRIT EUR, V31B, P588, DOI 10.1016/j.jhsb.2006.07.009
   DUNCAN RW, 1993, J HAND SURG-AM, V18A, P387, DOI 10.1016/0363-5023(93)90080-M
   EARLEY MJ, 1987, BRIT J PLAST SURG, V40, P333, DOI 10.1016/0007-1226(87)90035-X
   Ege A, 2002, ISRAEL MED ASSOC J, V4, P421
   Eisenhardt SU, 2012, J PLAST RECONSTR AES, V65, P640, DOI 10.1016/j.bjps.2011.11.037
   Eisenhardt SU, 2010, J RECONSTR MICROSURG, V26, P615, DOI 10.1055/s-0030-1267378
   El-Sabbagh AH, 2011, J HAND MICROSURG, V3, P66, DOI 10.1007/s12593-011-0042-y
   Engelhardt TO, 2012, MICROSURG, V32, P158, DOI 10.1002/micr.20951
   Fang P, 2002, J BURN CARE REHABIL, V23, P327, DOI 10.1097/00004630-200209000-00005
   Fassio E, 1999, ANN PLAS SURG, V43, P77, DOI 10.1097/00000637-199907000-00012
   Fitton AR, 2001, BRIT J PLAST SURG, V54, P208, DOI 10.1054/bjps.2000.3525
   Fitzgerald R H Jr, 1977, J Hand Surg Am, V2, P85
   Fotopoulos P, 2003, J RECONSTR MICROSURG, V19, P555
   FREELAND AE, 1984, J HAND SURG-AM, V9, P22, DOI 10.1016/S0363-5023(84)80179-3
   FREELAND AE, 1988, HAND CLIN, V4, P425
   Gedebou T M, 2002, Handchir Mikrochir Plast Chir, V34, P239, DOI 10.1055/s-2002-36290
   Georgescu AV, 2007, MICROSURG, V27, P384, DOI 10.1002/micr.20376
   Giessler GA, 2003, HAND CLIN, V19, P63, DOI 10.1016/S0749-0712(02)00128-2
   Giessler GA, 2011, J RECONSTR MICROSURG, V27, P567, DOI 10.1055/s-0031-1287672
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   GOTTLIEB LJ, 1994, PLAST RECONSTR SURG, V93, P1503, DOI 10.1097/00006534-199406000-00027
   Gregory H, 2007, J PLAST RECONSTR AES, V60, P731, DOI 10.1016/j.bjps.2007.03.011
   Gupta A, 2000, Instr Course Lect, V49, P377
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Hanasono MM, 2007, ANN PLAS SURG, V58, P573, DOI 10.1097/01.sap.0000237638.93453.66
   Hansen Adam J, 2007, Hand (N Y), V2, P159, DOI 10.1007/s11552-007-9041-7
   HARRIS K, 1986, AM J PHYSIOL, V250, pH213, DOI 10.1152/ajpheart.1986.250.2.H213
   Haughton Dn, 2012, Open Orthop J, V6, P43, DOI 10.2174/1874325001206010043
   Hauser Carl J, 2006, Surg Infect (Larchmt), V7, P379
   HEIMBACH D, 1988, ANN SURG, V208, P313, DOI 10.1097/00000658-198809000-00008
   Ho AM, 2010, J HAND SURG-AM, V35A, P308, DOI 10.1016/j.jhsa.2009.11.015
   Hoffman RD, 2003, HAND CLIN, V19, P33, DOI 10.1016/S0749-0712(02)00055-0
   Ignatiadis IA, 2008, INJURY, V39, pS116, DOI 10.1016/j.injury.2008.06.009
   INOUE G, 1988, Journal of Reconstructive Microsurgery, V4, P131, DOI 10.1055/s-2007-1006911
   Isago T, 2003, J DERMATOL, V30, P673, DOI 10.1111/j.1346-8138.2003.tb00456.x
   Jeschke MG, 2004, PLAST RECONSTR SURG, V113, P525, DOI 10.1097/01.PRS.0000100813.39746.5A
   Jihui JU, 2009, INJURY, V40, P1320, DOI 10.1016/j.injury.2009.04.009
   JIN YT, 1985, ANN PLAS SURG, V15, P340, DOI 10.1097/00000637-198510000-00011
   Kamolz LP, 2013, BURNS, V39, P814, DOI 10.1016/j.burns.2012.09.019
   Kang GCW, 2008, INT WOUND J, V5, P45, DOI 10.1111/j.1742-481X.2007.00369.x
   Kappel D A, 1985, Hand Clin, V1, P677
   Katrana F, 2008, J HAND SURG-EUR VOL, V33E, P800, DOI 10.1177/1753193408096021
   KATSAROS J, 1991, PLAST RECONSTR SURG, V87, P902, DOI 10.1097/00006534-199105000-00015
   Knobloch K, 2010, PLAST RECONSTR SURG, V126, p220E, DOI 10.1097/PRS.0b013e3181ec1eef
   Koch H, 2005, BRIT J PLAST SURG, V58, P1131, DOI 10.1016/j.bjps.2005.04.047
   Kömürcü M, 2008, INT ORTHOP, V32, P257, DOI 10.1007/s00264-006-0312-7
   Koshima Isao, 2000, Plast Reconstr Surg, V105, P2358, DOI 10.1097/00006534-200006000-00007
   LAI CS, 1991, BRIT J PLAST SURG, V44, P165, DOI 10.1016/0007-1226(91)90119-5
   Lee DL, 2011, INT WOUND J, V8, P406, DOI 10.1111/j.1742-481X.2011.00813.x
   Lee N, 2009, J PLAST RECONSTR AES, V62, pE584, DOI 10.1016/j.bjps.2008.11.118
   Lee Yao-Chou, 2011, Plast Surg Int, V2011, P127353, DOI 10.1155/2011/127353
   LISTER G, 1988, J HAND SURG-AM, V13A, P22, DOI 10.1016/0363-5023(88)90193-1
   Llanos S, 2006, ANN SURG, V244, P700, DOI 10.1097/01.sla.0000217745.56657.e5
   Lu LJ, 2007, J PLAST RECONSTR AES, V60, P876, DOI 10.1016/j.bjps.2006.11.024
   Lutz BS, 1999, PLAST RECONSTR SURG, V103, P132, DOI 10.1097/00006534-199901000-00021
   Madsen MS, 1996, INJURY, V27, P275, DOI 10.1016/0020-1383(95)00224-3
   MARUYAMA Y, 1990, BRIT J PLAST SURG, V43, P24, DOI 10.1016/0007-1226(90)90041-W
   Mathes SJ., 1997, RECONSTRUCTIVE SURG, VVol. 1, P9
   MCLAIN RF, 1991, J HAND SURG-AM, V16A, P108, DOI 10.1016/S0363-5023(10)80022-X
   Meky M, 2013, J HAND SURG-EUR VOL, V38E, P366, DOI 10.1177/1753193411427648
   MELONE CP, 1982, J HAND SURG-AM, V7, P291, DOI 10.1016/S0363-5023(82)80182-2
   Moisidis E, 2004, PLAST RECONSTR SURG, V114, P917, DOI 10.1097/01.PRS.0000133168.57199.E1
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Molski M, 2007, J PLAST RECONSTR AES, V60, P748, DOI 10.1016/j.bjps.2007.03.009
   Mouës CM, 2011, AM J SURG, V201, P544, DOI 10.1016/j.amjsurg.2010.04.029
   Murray RC, 2011, MICROSURG, V31, P104, DOI 10.1002/micr.20833
   Neumeister Michael, 2010, Semin Plast Surg, V24, P77, DOI 10.1055/s-0030-1253245
   Neumeister MW, 2003, HAND CLIN, V19, P1, DOI 10.1016/S0749-0712(02)00141-5
   NINKOVIC M, 1995, J HAND SURG-BRIT EUR, V20B, P53, DOI 10.1016/S0266-7681(05)80017-8
   Ofer N, 2007, J PLAST RECONSTR AES, V60, P724, DOI 10.1016/j.bjps.2006.12.010
   Page R, 2006, J HAND SURG-AM, V31A, P847, DOI 10.1016/j.jhsa.2006.02.024
   Park CA, 2009, ANN PLAS SURG, V62, P164, DOI 10.1097/SAP.0b013e31817d87cb
   PATZAKIS MJ, 1989, CLIN ORTHOP RELAT R, P36
   PATZAKIS MJ, 1974, J BONE JOINT SURG AM, VA 56, P532, DOI 10.2106/00004623-197456030-00010
   PEACOCK KC, 1988, J HAND SURG-AM, V13A, P960, DOI 10.1016/0363-5023(88)90281-X
   PEDERSON WC, 2011, GREENS OPERATIVE HAN
   Peek A, 2009, PLAST RECONSTR SURG, V123, P578, DOI 10.1097/PRS.0b013e3181956519
   PEIMER CA, 1981, J HAND SURG-AM, V6, P111, DOI 10.1016/S0363-5023(81)80164-5
   Petkar KS, 2011, BURNS, V37, P925, DOI 10.1016/j.burns.2011.05.013
   PUN WK, 1991, J HAND SURG-AM, V16A, P113, DOI 10.1016/S0363-5023(10)80023-1
   PUN WK, 1989, J HAND SURG-AM, V14A, P474, DOI 10.1016/S0363-5023(89)80006-1
   Pyle Jeremy W, 2010, Hand (N Y), V5, P318, DOI 10.1007/s11552-009-9252-1
   QUABA AA, 1990, BRIT J PLAST SURG, V43, P28, DOI 10.1016/0007-1226(90)90042-X
   RINALDI E, 1987, J HAND SURG-AM, V12A, P282, DOI 10.1016/S0363-5023(87)80290-3
   Rizzo M, 2012, J HAND SURG-AM, V37A, P583, DOI 10.1016/j.jhsa.2011.11.007
   Saint-Cyr M, 2006, J HAND SURG-BRIT EUR, V31B, P168, DOI 10.1016/j.jhsb.2004.10.020
   Saint-Cyr M, 2006, HAND CLIN, V22, P317, DOI 10.1016/j.hcl.2006.03.006
   SCHEKER LR, 1993, J HAND SURG-BRIT EUR, V18B, P568, DOI 10.1016/0266-7681(93)90005-Z
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   Sebastin SJ, 2011, PLAST RECONSTR SURG, V128, p166E, DOI 10.1097/PRS.0b013e318221ddfa
   Shahzad MN, 2012, J PAK MED ASSOC, V62, P950
   SHIBATA T, 1993, J HAND SURG-BRIT EUR, V18B, P225, DOI 10.1016/0266-7681(93)90115-V
   SLOAN JP, 1987, J HAND SURG-BRIT EUR, V12B, P123, DOI 10.1016/0266-7681(87)90076-3
   SONG RY, 1982, CLIN PLAST SURG, V9, P27
   SONG YG, 1984, BRIT J PLAST SURG, V37, P149, DOI 10.1016/0007-1226(84)90002-X
   Spyropoulou Alexandra, 2010, Semin Plast Surg, V24, P34, DOI 10.1055/s-0030-1253244
   Stahl S, 1999, SCAND J PLAST RECONS, V33, P117, DOI 10.1080/02844319950159721
   Stahl Stephane, 2010, Eplasty, V10, pe21
   Stevenson J, 2003, J HAND SURG-BRIT EUR, V28B, P388, DOI 10.1016/S0266-7681(03)00175-X
   Strickland JW, 1982, ORTHOP REV, V11, P39
   Sundine M, 1996, J HAND SURG-BRIT EUR, V21B, P216, DOI 10.1016/S0266-7681(96)80102-1
   SUPROCK MD, 1990, J HAND SURG-AM, V15A, P761, DOI 10.1016/0363-5023(90)90152-H
   SWANSON TV, 1991, J HAND SURG-AM, V16A, P101, DOI 10.1016/S0363-5023(10)80021-8
   Tan O, 2010, J PLAST RECONSTR AES, V63, P146, DOI 10.1016/j.bjps.2008.03.025
   Taras JS, 2010, J HAND SURG-AM, V35A, P415, DOI 10.1016/j.jhsa.2009.12.008
   Tarkin IS, 2008, J ORTHOP TRAUMA, V22, pS146, DOI 10.1097/BOT.0b013e318188e2bc
   Terzis JK, 2009, PLAST RECONSTR SURG, V124, P1225, DOI 10.1097/PRS.0b013e3181b5a322
   Tränkle M, 2003, J HAND SURG-AM, V28A, P758, DOI 10.1016/S0363-5023(03)00369-1
   Ulrich D, 2010, ARCH ORTHOP TRAUM SU, V130, P217, DOI 10.1007/s00402-009-0845-5
   Ulusal BG, 2007, ANN PLAS SURG, V58, P173, DOI 10.1097/01.sap.0000232832.18894.2b
   Unal C, 2011, J RECONSTR MICROSURG, V27, P559, DOI 10.1055/s-0031-1287671
   Vedder N., 2011, GREENS OPERATIVE HAN, V6th, P1603
   VILAIN R, 1973, PLAST RECONSTR SURG, V51, P397, DOI 10.1097/00006534-197304000-00006
   Watt AJ, 2012, HAND CLIN, V28, P519, DOI 10.1016/j.hcl.2012.08.010
   WEI FC, 1988, PLAST RECONSTR SURG, V82, P346, DOI 10.1097/00006534-198808000-00026
   Wei FC, 2002, PLAST RECONSTR SURG, V109, P2227, DOI 10.1097/00006534-200206000-00008
   Wei FC, 2002, PLAST RECONSTR SURG, V109, P2219, DOI 10.1097/00006534-200206000-00007
   Weigert R, 2011, J HAND SURG-EUR VOL, V36E, P185, DOI 10.1177/1753193410387329
   Weinand C, 2009, J BURN CARE RES, V30, P362, DOI 10.1097/BCR.0b013e318198a77e
   WILKINS J, 1991, ORTHOP CLIN N AM, V22, P433
   WINTSCH K, 1986, Journal of Reconstructive Microsurgery, V2, P143, DOI 10.1055/s-2007-1007014
   Wong MZ, 2012, ANN PLAS SURG, V69, P265, DOI 10.1097/SAP.0b013e3182223e56
   Yam A, 2008, J HAND SURG-AM, V33A, P1889, DOI 10.1016/j.jhsa.2008.08.015
   YANG JY, 1991, ANN PLAS SURG, V27, P258, DOI 10.1097/00000637-199109000-00010
   Yazar S, 2008, J PLAST RECONSTR AES, V61, P1549, DOI 10.1016/j.bjps.2008.06.016
   Yidirim S, 2006, J RECONSTR MICROSURG, V22, P599, DOI 10.1055/s-2006-956234
   Zhang X, 2012, J RECONSTR MICROSURG, V28, P167, DOI 10.1055/s-0031-1301067
NR 158
TC 5
Z9 6
U1 0
U2 2
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0749-0712
EI 1558-1969
J9 HAND CLIN
JI Hand Clin.
PD NOV
PY 2013
VL 29
IS 4
BP 551
EP +
DI 10.1016/j.hcl.2013.08.008
PG 18
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 260CS
UT WOS:000327573200010
PM 24209953
DA 2026-07-24
ER

PT J
AU Liu, ZM
   Dumville, JC
   Hinchliffe, RJ
   Cullum, N
   Game, F
   Stubbs, N
   Sweeting, M
   Peinemann, F
AF Liu, Zhenmi
   Dumville, Jo C.
   Hinchliffe, Robert J.
   Cullum, Nicky
   Game, Fran
   Stubbs, Nikki
   Sweeting, Michael
   Peinemann, Frank
TI Negative pressure wound therapy for treating foot wounds in people with
   diabetes mellitus
SO COCHRANE DATABASE OF SYSTEMATIC REVIEWS
LA English
DT Review
DE Amputation; Bandages; Wound Healing; Debridement; Diabetic Foot
   [surgery]; Negative-Pressure Wound Therapy [adverse effects; methods];
   Randomized Controlled Trials as Topic; Humans
ID VACUUM-ASSISTED-CLOSURE; QUALITY-OF-LIFE; CALCIUM ALGINATE DRESSINGS;
   CLASSIFICATION-SYSTEM; ULCERS; MANAGEMENT; AMPUTATION; MOIST;
   MULTICENTER; TRIAL
AB Background
   Foot wounds in people with diabetes mellitus (DM) are a common and serious global health issue. People with DM are prone to developing foot ulcers and, if these do not heal, they may also undergo foot amputation surgery resulting in postoperative wounds. Negative pressure wound therapy (NPWT) is a technology that is currently used widely in wound care. NPWT involves the application of a wound dressing attached to a vacuum suction machine. A carefully controlled negative pressure (or vacuum) sucks wound and tissue fluid away from the treated area into a canister. A clear and current overview of current evidence is required to facilitate decision making regarding its use.
   Objectives
   To assess the effects of negative pressure wound therapy compared with standard care or other therapies in the treatment of foot wounds in people with DM in any care setting.
   Search methods
   In January 2018, for this first update of this review, we searched the Cochrane Wounds Specialised Register; the Cochrane Central Register of Controlled Trials (CENTRAL); Ovid MEDLINE (including In-Process & Other Non-Indexed Citations); Ovid Embase and EBSCO CINAHL Plus. We also searched clinical trials registries for ongoing and unpublished studies, and scanned reference lists of relevant included studies, reviews, meta-analyses and health technology reports to identify additional studies. There were no restrictions with respect to language, date of publication or study setting. We identified six additional studies for inclusion in the review.
   Selection criteria
   Published or unpublished randomised controlled trials (RCTs) that evaluated the effects of any brand of NPWT in the treatment of foot wounds in people with DM, irrespective of date or language of publication. Particular effort was made to identify unpublished studies.
   Data collection and analysis
   Two review authors independently performed study selection, risk of bias assessment and data extraction. Initial disagreements were resolved by discussion, or by including a third review author when necessary. We presented and analysed data separately for foot ulcers and postoperative wounds.
   Main results
   Eleven RCTs (972 participants) met the inclusion criteria. Study sample sizes ranged from 15 to 341 participants. One study had three arms, which were all included in the review. The remaining 10 studies had two arms. Two studies focused on postamputation wounds and all other studies included foot ulcers in people with DM. Ten studies compared NPWT with dressings; and one study compared NPWT delivered at 75 mmHg with NPWT delivered at 125 mmHg. Our primary outcome measures were the number of wounds healed and time to wound healing.
   NPWT compared with dressings for postoperative wounds
   Two studies (292 participants) compared NPWT with moist wound dressings in postoperative wounds (postamputation wounds). Only one study specified a follow-up time, which was 16 weeks. This study (162 participants) reported an increased number of healed wounds in the NPWT group compared with the dressings group (risk ratio (RR) 1.44, 95% confidence interval (CI) 1.03 to 2.01; low-certainty evidence, downgraded for risk of bias and imprecision). This study also reported that median time to healing was 21 days shorter with NPWT compared with moist dressings (hazard ratio (HR) calculated by review authors 1.91, 95% CI 1.21 to 2.99; low-certainty evidence, downgraded for risk of bias and imprecision). Data from the two studies suggest that it is uncertain whether there is a difference between groups in amputation risk (RR 0.38, 95% CI 0.14 to 1.02; 292 participants; very low-certainty evidence, downgraded once for risk of bias and twice for imprecision).
   NPWT compared with dressings for foot ulcers
   There were eight studies (640 participants) in this analysis and follow-up times varied between studies. Six studies (513 participants) reported the proportion of wounds healed and data could be pooled for five studies. Pooled data (486 participants) suggest that NPWT may increase the number of healed wounds compared with dressings (RR 1.40, 95% CI 1.14 to 1.72; I-2 = 0%; low-certainty evidence, downgraded once for risk of bias and once for imprecision). Three studies assessed time to healing, but only one study reported usable data. This study reported that NPWT reduced the time to healing compared with dressings (hazard ratio (HR) calculated by review authors 1.82, 95% CI 1.27 to 2.60; 341 participants; low-certainty evidence, downgraded once for risk of bias and once for imprecision).
   Data from three studies (441 participants) suggest that people allocated to NPWT may be at reduced risk of amputation compared with people allocated to dressings (RR 0.33, 95% CI 0.15 to 0.70; I-2 = 0%; low-certainty evidence; downgraded once for risk of bias and once for imprecision).
   Low-pressure compared with high-pressure NPWT for foot ulcers
   One study (40 participants) compared NPWT 75 mmHg and NPWT 125 mmHg. Follow-up time was four weeks. There were no data on primary outcomes. There was no clear difference in the number of wounds closed or covered with surgery between groups (RR 0.83, 95% CI 0.47 to 1.47; very low-certainty evidence, downgraded once for risk of bias and twice for serious imprecision) and adverse events (RR 1.50, 95% CI 0.28 to 8.04; very low-certainty evidence, downgraded once for risk of bias and twice for serious imprecision).
   Authors' conclusions
   There is low-certainty evidence to suggest that NPWT, when compared with wound dressings, may increase the proportion of wounds healed and reduce the time to healing for postoperative foot wounds and ulcers of the foot in people with DM. For the comparisons of different pressures of NPWT for treating foot ulcers in people with DM, it is uncertain whether there is a difference in the number of wounds closed or covered with surgery, and adverse events. None of the included studies provided evidence on time to closure or coverage surgery, health-related quality of life or cost-effectiveness. The limitations in current RCT evidence suggest that further trials are required to reduce uncertainty around decision-making regarding the use of NPWT to treat foot wounds in people with DM.
C1 [Liu, Zhenmi] Sichuan Univ, West China Hosp, West China Sch Publ Hlth, Chengdu 610041, Sichuan, Peoples R China.
   [Liu, Zhenmi; Dumville, Jo C.; Cullum, Nicky] Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol Med & Hlth, Div Nursing Midwifery & Social Work,Sch Hlth Sci, Manchester, Lancs, England.
   [Hinchliffe, Robert J.] St Georges Healthcare NHS Trust, St Georges Vasc Inst, London, England.
   [Game, Fran] Derby Hosp NHS Fdn Trust, Dept Diabet & Endocrinol, Derby, England.
   [Stubbs, Nikki] Leeds Community Healthcare NHS Trust, St Marys Hosp, Leeds, W Yorkshire, England.
   [Sweeting, Michael] Univ Leicester, Coll Life Sci, Dept Hlth Sci, Leicester, Leics, England.
   [Peinemann, Frank] Univ Cologne, Childrens Hosp, Pediat Oncol & Hematol, Cologne, Germany.
C3 Sichuan University; University of Manchester; City St Georges,
   University of London; University of Leicester; University of Cologne
RP Liu, ZM (通讯作者)，Sichuan Univ, West China Hosp, West China Sch Publ Hlth, Chengdu 610041, Sichuan, Peoples R China.
EM zhenmiliu@scu.edu.cn
RI ; Sweeting, Michael/U-3917-2019; Liu, Zhenmi/O-7046-2014; Cullum,
   Nicky/F-2438-2011; Dumville, Jo/O-7867-2014; /H-2800-2019
OI Hinchliffe, Robert/0000-0002-6370-0800; Sweeting,
   Michael/0000-0003-0980-8965; Game, Frances/0000-0002-5294-4789
FU Division of Nursing, Midwifery and Social Work, School of Health
   Sciences, Faculty of Biology, Medicine and Health, University of
   Manchester, UK, UK; National Institute for Health Research (NIHR), UK;
   NIHR, via Cochrane Infrastructure and Cochrane Programme Grant (NIHR
   Cochrane Programme) [13/89/08]; NIHR Manchester Biomedical Research
   Centre (BRC), UK; National Institute for Health Research Collaboration
   for Leadership in Applied Health Research and Care (NIHR CLAHRC),
   Greater Manchester, UK; National Institute for Health Research (NIHR)
   Systematic Review Fellowships, UK [NIHR-RMFI-2015-06-52]; NIHR
   Manchester BRC; NIHR CLAHRC, Greater Manchester; National Institute for
   Health Research [13/89/08, NF-SI-0512-10028] Funding Source:
   researchfish
FX Internal sources Division of Nursing, Midwifery and Social Work, School
   of Health Sciences, Faculty of Biology, Medicine and Health, University
   of Manchester, UK, UK. External sources National Institute for Health
   Research (NIHR), UK. This project was supported by the NIHR, via
   Cochrane Infrastructure and Cochrane Programme Grant funding (NIHR
   Cochrane Programme Grant 13/89/08 - High Priority Cochrane Reviews in
   Wound Prevention and Treatment) to Cochrane Wounds. The views and
   opinions expressed herein are those of the authors and do not
   necessarily reflect those of the Systematic Reviews Programme, the NIHR,
   the NHS or the Department of Health. NIHR Manchester Biomedical Research
   Centre (BRC), UK. This research was co-funded by the NIHR Manchester
   BRC. The views expressed in this publication are those of the authors
   and not necessarily those of the NHS, the National Institute for Health
   Research or the Department of Health. National Institute for Health
   Research Collaboration for Leadership in Applied Health Research and
   Care (NIHR CLAHRC), Greater Manchester, UK. Nicky Cullum and Jo
   Dumville's work on this project was partly funded by the NIHR CLAHRC,
   Greater Manchester. The funder had no role in the decision to publish,
   or preparation of the manuscript. However, the review may be considered
   to be affiliated to the work of the NIHR CLAHRC Greater Manchester. The
   views expressed herein are those of the authors and not necessarily
   those of the NHS, NIHR or the Department of Health. National Institute
   for Health Research (NIHR) Systematic Review Fellowships
   (NIHR-RMFI-2015-06-52 Zhenmi Liu), UK.
CR Abbott CA, 2002, DIABETIC MED, V19, P377, DOI 10.1046/j.1464-5491.2002.00698.x
   [Anonymous], ONT HLTH TECHN ASS S
   [Anonymous], DIAB FOOT PROBL PREV
   [Anonymous], 2024, The ISSG search filter resource
   [Anonymous], 2009, BMJ-BRIT MED J, V21, P7, DOI [DOI 10.1136/bmj.b2535, 10.1371/journal.pmed.1000097, DOI 10.7326/0003-4819-151-4-200908180-00135]
   [Anonymous], 20 ANN S ADV WOUNDS
   [Anonymous], COMP PRIC NEG PRESS
   [Anonymous], 2010, DIAB UK 2010 KEY STA
   [Anonymous], OSTOMY WOUND MANAGEM
   [Anonymous], 20 ANN S ADV CAR WOU
   [Anonymous], IMPR FOOTC PEOPL DIA
   [Anonymous], INT BEST PRACT GUID
   [Anonymous], 2 WORLD UN WOUND HEA
   [Anonymous], GLOB REP DIAB
   [Anonymous], 2 WORLD UN WOUND HEA
   [Anonymous], Interpreting results and drawing conclusions | Cochrane Training
   [Anonymous], GRADEPRO GUID DEV TO
   [Anonymous], 3 C WORLD UN WOUND H
   [Anonymous], DIV DIAB TRANSL
   [Anonymous], 2011, COCHRANE HDB SYSTEMA
   [Anonymous], REV MAN 5 REVMAN 5
   [Anonymous], AHRQ PUBLICATION
   [Anonymous], IDF Diabetes Atlas
   [Anonymous], DIAB PREV
   Apelqvist J, 2000, DIABETES-METAB RES, V16, pS75, DOI 10.1002/1520-7560(200009/10)16:1+<::AID-DMRR139>3.3.CO;2-#
   Apelqvist J, 2000, DIABETES-METAB RES, V16, pS84, DOI 10.1002/1520-7560(200009/10)16:1+<::AID-DMRR113>3.0.CO;2-S
   Apelqvist J, 2008, AM J SURG, V195, P782, DOI 10.1016/j.amjsurg.2007.06.023
   Armstrong David G, 2007, Int Wound J, V4, P79, DOI 10.1111/j.1742-481X.2006.00270.x
   Armstrong DG, 2012, WOUND REPAIR REGEN, V20, P332, DOI 10.1111/j.1524-475X.2012.00780.x
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   Chong SJ, 2011, DIVING HYPERB MED, V41, P147
   Dalla PL, 2010, J Diabet Foot Complicat, V2, P33
   Deeks JJ, 2002, STAT MED, V21, P1575, DOI 10.1002/sim.1188
   Dorresteijn JAN, 2010, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD007610.pub2
   Driver VR, 2014, J AM PODIAT MED ASSN, V104, P374
   Driver VR, 2014, J AM PODIAT MED ASSN, V104, P147, DOI 10.7547/0003-0538-104.2.147
   Dumville JC, 2012, DIABETOLOGIA, V55, P1902, DOI 10.1007/s00125-012-2558-5
   Dumville JC, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD010318.pub2
   Dumville JC, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006215.pub3
   Dumville JC, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009099.pub2
   Dumville JC, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009111.pub2
   Eginton MT, 2003, ANN VASC SURG, V17, P645, DOI 10.1007/s10016-003-0065-3
   Eneroth M, 2008, DIABETES-METAB RES, V24, pS76, DOI 10.1002/dmrr.852
   Etöz A, 2004, WOUNDS, V16, P264
   Formosa C, 2015, DIABETIC MED, V32, P59
   Game FL, 2012, DIABETES-METAB RES, V28, P119, DOI 10.1002/dmrr.2246
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Gonzalez IG, 2017, WORLD J SURG, V41, P386, DOI 10.1007/s00268-016-3782-9
   Guy Heidi, 2012, Nurs Times, V108, P20
   Guyatt GH, 2008, BMJ-BRIT MED J, V336, P995, DOI 10.1136/bmj.39490.551019.BE
   Higgins J., 2011, CHAPTER 8 ASSESSING
   Higgins JPT., 2003, BM, V327, P557, DOI [DOI 10.1136/BMJ.D5928, DOI 10.1016/J.SURG.2009.06.030]
   Holman N, 2012, DIABETOLOGIA, V55, P1919, DOI 10.1007/s00125-012-2468-6
   Hróbjartsson A, 2012, BMJ-BRIT MED J, V344, DOI 10.1136/bmj.e1119
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Ince P, 2008, DIABETES CARE, V31, P964, DOI 10.2337/dc07-2367
   Karatepe O, 2011, ACTA CHIR BELG, V111, P298, DOI 10.1080/00015458.2011.11680757
   Karthikesalingam A, 2010, DIABETIC MED, V27, P544, DOI 10.1111/j.1464-5491.2010.02989.x
   Kerr M, 2014, DIABETIC MED, V31, P1498, DOI 10.1111/dme.12545
   Kontopantelis E, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0069930
   KUMAR S, 1994, DIABETIC MED, V11, P480, DOI 10.1111/j.1464-5491.1994.tb00310.x
   Lavery LA, 2014, PLAST RECONSTR SURG, V133, P722, DOI 10.1097/01.prs.0000438046.83515.6a
   Lebrun E, 2010, WOUND REPAIR REGEN, V18, P433, DOI 10.1111/j.1524-475X.2010.00619.x
   Liu S, 2017, THER CLIN RISK MANAG, V13, DOI 10.2147/TCRM.S131193
   Lone AM, 2014, DIABET FOOT ANKLE, V5, DOI 10.3402/dfa.v5.23345
   Maggio G, 2010, EUR J CLIN INVEST, V40, P87
   Margolis DJ, 1999, DIABETES CARE, V22, P692, DOI 10.2337/diacare.22.5.692
   McCallon S K, 2000, Ostomy Wound Manage, V46, P28
   Mody GN, 2008, OSTOMY WOUND MANAG, V54, P36
   Moghazy AM, 2015, EUR J PLAST SURG, V38, P463, DOI 10.1007/s00238-015-1140-z
   Morris AD, 1998, DIABETES CARE, V21, P738, DOI 10.2337/diacare.21.5.738
   Moues C M, 2005, J Wound Care, V14, P224
   Nabuurs-Franssen MH, 2005, DIABETOLOGIA, V48, P1906, DOI 10.1007/s00125-005-1856-6
   Nain Prabhdeep Singh, 2011, J Surg Tech Case Rep, V3, P17, DOI 10.4103/2006-8808.78466
   Noble-Bell G, 2008, INT WOUND J, V5, P233, DOI 10.1111/j.1742-481X.2008.00430.x
   Novinscak Tomislav, 2010, Acta Medica Croatica, V64, P113
   Oyibo SO, 2001, DIABETES CARE, V24, P84, DOI 10.2337/diacare.24.1.84
   Parmar MKB, 1998, STAT MED, V17, P2815, DOI 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8
   PECORARO RE, 1990, DIABETES CARE, V13, P513, DOI 10.2337/diacare.13.5.513
   Peinemann F, 2008, BMC MED RES METHODOL, V8, DOI 10.1186/1471-2288-8-4
   Perez D, 2010, AM J SURG, V199, P14, DOI 10.1016/j.amjsurg.2008.12.029
   Pound N, 2005, DIABETIC MED, V22, P1306, DOI 10.1111/j.1464-5491.2005.01640.x
   Rahmanian-Schwarz A, 2012, BURNS, V38, P573, DOI 10.1016/j.burns.2011.10.010
   Ravari Hassan, 2013, J Cutan Aesthet Surg, V6, P17, DOI 10.4103/0974-2077.110091
   Reiber GE, 1996, DIABETIC MED, V13, pS6, DOI 10.1002/dme.1996.13.s1.6
   Reiber GE, 1999, DIABETES CARE, V22, P157, DOI 10.2337/diacare.22.1.157
   Riaz MU, 2010, PAK J MED HEALTH SCI, V4, P308
   Ribu L, 2007, QUAL LIFE RES, V16, P179, DOI 10.1007/s11136-006-0031-y
   Sajid MT, 2015, JCPSP-J COLL PHYSICI, V25, P789, DOI 11.2015/JCPSP.789793
   Schaper NC, 2004, DIABETES-METAB RES, V20, pS90, DOI 10.1002/dmrr.464
   Sepúlveda G, 2009, CIR ESPAN, V86, P171, DOI 10.1016/j.ciresp.2009.03.020
   Shaw JE, 2010, DIABETES RES CLIN PR, V87, P4, DOI 10.1016/j.diabres.2009.10.007
   Singh N, 2005, JAMA-J AM MED ASSOC, V293, P217, DOI 10.1001/jama.293.2.217
   Steed DL, 2006, WOUND REPAIR REGEN, V14, P680, DOI 10.1111/j.1524-475X.2006.00176.x
   [孙剑伟 Sun JW], 2007, [中国组织工程研究与临床康复, Journal of Clinical Rehabilitative Tissue Engineering Research], V11, P8908
   Sun Yong, 2015, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V29, P812
   Tennvall GR, 2000, J DIABETES COMPLICAT, V14, P235
   Tuncel U, 2013, INT WOUND J, V10, P152, DOI 10.1111/j.1742-481X.2012.00955.x
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   Ugurlar M, 2017, FOOT ANKLE SURG, V23, P173, DOI 10.1016/j.fas.2016.05.314
   Vaidhya N, 2015, INDIAN J SURG, V77, pS525, DOI 10.1007/s12262-013-0907-3
   Van Gils CC, 1999, DIABETES CARE, V22, P678, DOI 10.2337/diacare.22.5.678
   Vassallo IM, 2015, WOUNDS, V27, P180
   Wagner F W Jr, 1981, Foot Ankle, V2, P64
   [汪涛 Wang Tao], 2016, [上海交通大学学报. 医学版, Journal of Shanghai Jiaotong University .Medical Science], V36, P1159
   Wrobel JS, 2001, DIABETES CARE, V24, P860, DOI 10.2337/diacare.24.5.860
   Yang SL, 2017, FOOT ANKLE INT, V38, P893, DOI 10.1177/1071100717704940
   Yang SL, 2014, WOUND REPAIR REGEN, V22, P548, DOI 10.1111/wrr.12195
   [杨少玲 Yang Shaoling], 2017, [解放军医学杂志, Medical Journal of Chinese People's Liberation Army], V42, P224
   Zhang Meiguang, 2014, Zhonghua Shao Shang Za Zhi, V30, P116
   Zhang XX, 2017, INT J CLIN EXP MED, V10, P12942
   [朱新华 Zhu Xinhua], 2014, [中国组织工程研究, Chinese Journal of Tissue Engineering Research], V18, P5548
NR 114
TC 140
Z9 169
U1 1
U2 71
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1469-493X
EI 1361-6137
J9 COCHRANE DB SYST REV
JI Cochrane Database Syst Rev.
PY 2018
IS 10
AR CD010318
DI 10.1002/14651858.CD010318.pub3
PG 84
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GZ0JU
UT WOS:000449049600046
PM 30328611
OA Green Published, hybrid
DA 2026-07-24
ER

PT J
AU Baillot, R
   Dumont, É
   Voisine, P
AF Baillot, Richard
   Dumont, Eric
   Voisine, Pierre
TI Sternal reentry in a patient with previous deep sternal wound infection
   managed with horizontal titanium plate fixation
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; THERAPY; COMPLICATIONS
AB Redo open-heart surgery and sternal reentry in patients with previous deep sternal wound infection (DSWI) and absence of sternal integrity can be a delicate and morbid task due the lack of a dissection plane between the heart and the surrounding soft tissues. Delayed sternal reconstruction and osteosynthesis with horizontal titanium plating fixation (Synthes) following vacuum assisted therapy (KCI) has recently been proposed and adopted for the treatment of DSWI. We present such a case of a patient who was successfully reoperated for valve replacement three years after coronary artery bypass grafting complicated by DSWI and initially treated with titanium plate fixation.
C1 [Baillot, Richard; Dumont, Eric; Voisine, Pierre] Univ Laval, Dept Cardiac Surg, Quebec City, PQ, Canada.
C3 Laval University
RP Baillot, R (通讯作者)，Univ Laval, Dept Cardiac Surg, Quebec City, PQ, Canada.
EM richard.baillot@chg.ulaval.ca
CR Baillot R, 2010, EUR J CARDIO-THORAC, V37, P880, DOI 10.1016/j.ejcts.2009.09.023
   Cicilioni OJ, 2005, PLAST RECONSTR SURG, V115, P1297, DOI 10.1097/01.PRS.0000156918.15595.85
   Douville EC, 2004, ANN THORAC SURG, V78, P1659, DOI 10.1016/j.athoracsur.2004.04.082
   Gaudreau G, 2010, EUR J CARDIO-THORAC, V37, P888, DOI 10.1016/j.ejcts.2009.07.043
   LOOP FD, 1990, ANN THORAC SURG, V49, P179, DOI 10.1016/0003-4975(90)90136-T
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Raman Jai, 2006, Interact Cardiovasc Thorac Surg, V5, P336, DOI 10.1510/icvts.2005.121863
   SARGENT LA, 1991, ANN THORAC SURG, V52, P490, DOI 10.1016/0003-4975(91)90910-I
   Schimmer C, 2008, THORAC CARDIOV SURG, V56, P200, DOI 10.1055/s-2008-1038386
   Zajarias A, 2009, J AM COLL CARDIOL, V53, P1829, DOI 10.1016/j.jacc.2008.11.059
NR 10
TC 2
Z9 3
U1 0
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD JUL 22
PY 2010
VL 5
AR 56
DI 10.1186/1749-8090-5-56
PG 4
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 656MD
UT WOS:000282338700001
PM 20649955
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Webster, J
   Liu, ZM
   Norman, G
   Dumville, JC
   Chiverton, L
   Scuffham, P
   Stankiewicz, M
   Chaboyer, WP
AF Webster, Joan
   Liu, Zhenmi
   Norman, Gill
   Dumville, Jo C.
   Chiverton, Laura
   Scuffham, Paul
   Stankiewicz, Monica
   Chaboyer, Wendy P.
TI Negative pressure wound therapy for surgical wounds healing by primary
   closure
SO COCHRANE DATABASE OF SYSTEMATIC REVIEWS
LA English
DT Review
DE *Skin Transplantation; *Wound Healing; Bandages; Negative-Pressure Wound
   Therapy [instrumentation; *methods]; Orthopedic Procedures; Randomized
   Controlled Trials as Topic; Surgical Procedures, Operative; Surgical
   Wound Dehiscence [prevention & control]; Wounds and Injuries [surgery];
   Humans
ID VACUUM-ASSISTED-CLOSURE; RANDOMIZED CONTROLLED-TRIAL; SITE INFECTION;
   COST-EFFECTIVENESS; CESAREAN-SECTION; CLINICAL-EFFICACY;
   CARDIAC-SURGERY; OBESE-PATIENTS; PRIMARY HIP; INCISION
AB Background
   Indications for the use of negative pressure wound therapy (NPWT) are broad and include prophylaxis for surgical site infections (SSIs). While existing evidence for the effectiveness of NPWT remains uncertain, new trials necessitated an updated review of the evidence for the effects of NPWT on postoperative wounds healing by primary closure.
   Objectives
   To assess the effects of negative pressure wound therapy for preventing surgical site infection in wounds healing through primary closure.
   Search methods
   We searched the Cochrane Wounds Specialised Register, CENTRAL, Ovid MEDLINE (including In-Process & Other Non-Indexed Citations), Ovid Embase, and EBSCO CINAHL Plus in February 2018. We also searched clinical trials registries for ongoing and unpublished studies, and checked reference lists of relevant included studies as well as reviews, meta-analyses, and health technology reports to identify additional studies. There were no restrictions on language, publication date, or setting.
   Selection criteria
   We included trials if they allocated participants to treatment randomly and compared NPWT with any other type of wound dressing, or compared one type of NPWT with another type of NPWT.
   Data collection and analysis
   Four review authors independently assessed trials using predetermined inclusion criteria. We carried out data extraction, 'Risk of bias' assessment using the Cochrane 'Risk of bias' tool, and quality assessment according to GRADE methodology.
   Main results
   In this second update we added 25 intervention trials, resulting in a total of 30 intervention trials (2957 participants), and two economic studies nested in trials. Surgeries included abdominal and colorectal (n = 5); caesarean section (n = 5); knee or hip arthroplasties (n = 5); groin surgery (n = 5); fractures (n = 5); laparotomy (n = 1); vascular surgery (n = 1); sternotomy (n = 1); breast reduction mammoplasty (n = 1); and mixed (n = 1). In three key domains four studies were at low risk of bias; six studies were at high risk of bias; and 20 studies were at unclear risk of bias. We judged the evidence to be of low or very low certainty for all outcomes, downgrading the level of the evidence on the basis of risk of bias and imprecision.
   Primary outcomes
   Three studies reported mortality (416 participants; follow-up 30 to 90 days or unspecified). It is uncertain whether NPWT has an impact on risk of death compared with standard dressings (risk ratio (RR) 0.63, 95% confidence interval (CI) 0.25 to 1.56; very low-certainty evidence, downgraded once for serious risk of bias and twice for very serious imprecision).
   Twenty-five studies reported on SSI. The evidence from 23 studies (2533 participants; 2547 wounds; follow-up 30 days to 12 months or unspecified) showed that NPWT may reduce the rate of SSIs (RR 0.67, 95% CI 0.53 to 0.85; low-certainty evidence, downgraded twice for very serious risk of bias).
   Fourteen studies reported dehiscence. We combined results from 12 studies (1507 wounds; 1475 participants; follow-up 30 days to an average of 113 days or unspecified) that compared NPWT with standard dressings. It is uncertain whether NPWT reduces the risk of wound dehiscence compared with standard dressings (RR 0.80, 95% CI 0.55 to 1.18; very low-certainty evidence, downgraded twice for very serious risk of bias and once for serious imprecision).
   Secondary outcomes
   We are uncertain whether NPWT increases or decreases reoperation rates when compared with a standard dressing (RR 1.09, 95% CI 0.73 to 1.63; 6 trials; 1021 participants; very low-certainty evidence, downgraded for very serious risk of bias and serious imprecision) or if there is any clinical benefit associated with NPWT for reducing wound-related readmission to hospital within 30 days (RR 0.86, 95% CI 0.47 to 1.57; 7 studies; 1271 participants; very low-certainty evidence, downgraded for very serious risk of bias and serious imprecision). It is also uncertain whether NPWT reduces incidence of seroma compared with standard dressings (RR 0.67, 95% CI 0.45 to 1.00; 6 studies; 568 participants; very low-certainty evidence, downgraded twice for very serious risk of bias and once for serious imprecision). It is uncertain if NPWT reduces or increases the risk of haematoma when compared with a standard dressing (RR 1.05, 95% CI 0.32 to 3.42; 6 trials; 831 participants; very low-certainty evidence, downgraded twice for very serious risk of bias and twice for very serious imprecision. It is uncertain if there is a higher risk of developing blisters when NPWT is compared with a standard dressing (RR 6.64, 95% CI 3.16 to 13.95; 6 studies; 597 participants; very low-certainty evidence, downgraded twice for very serious risk of bias and twice for very serious imprecision).
   Quality of life was not reported separately by group but was used in two economic evaluations to calculate quality-adjusted life years (QALYs). There was no clear difference in incremental QALYs for NPWT relative to standard dressing when results from the two trials were combined (mean difference 0.00, 95% CI -0.00 to 0.00; moderate-certainty evidence).
   One trial concluded that NPWT may be more cost-effective than standard care, estimating an incremental cost-effectiveness ratio (ICER) value of GBP 20.65 per QALY gained. A second cost-effectiveness study estimated that when compared with standard dressings NPWT was cost saving and improved QALYs. We rated the overall quality of the reports as very good; we did not grade the evidence beyond this as it was based on modelling assumptions.
   Authors' conclusions
   Despite the addition of 25 trials, results are consistent with our earlier review, with the evidence judged to be of low or very low certainty for all outcomes. Consequently, uncertainty remains about whether NPWT compared with a standard dressing reduces or increases the incidence of important outcomes such as mortality, dehiscence, seroma, or if it increases costs. Given the cost and widespread use of NPWT for SSI prophylaxis, there is an urgent need for larger, well-designed and well-conducted trials to evaluate the effects of newer NPWT products designed for use on clean, closed surgical incisions. Such trials should initially focus on wounds that may be difficult to heal, such as sternal wounds or incisions on obese patients.
C1 [Webster, Joan] Griffith Univ, Menzies Hlth Inst Queensland, Natl Ctr Res Excellence Nursing, Ctr Hlth Practice Innovat, Brisbane, Qld, Australia.
   [Webster, Joan] Univ Queensland, Sch Nursing & Midwifery, Brisbane, Qld, Australia.
   [Webster, Joan] Royal Brisbane & Womens Hosp, Nursing & Midwifery Res Ctr, Butterfield St, Herston, Qld 4029, Australia.
   [Liu, Zhenmi] Sichuan Univ, West China Hosp, West China Sch Publ Hlth, Chengdu, Sichuan, Peoples R China.
   [Norman, Gill; Dumville, Jo C.] Univ Manchester, Manchester Acad Hlth Sci Ctr, Div Nursing Midwifery & Social Work, Sch Hlth Sci,Fac Biol Med & Hlth, Manchester, Lancs, England.
   [Chiverton, Laura] Manchester Univ NHS Fdn Trust, St Marys Hosp, Neonatal Intens Care Unit, Manchester, Lancs, England.
   [Scuffham, Paul] Griffith Univ, Meadowbrook, Qld, Australia.
   [Stankiewicz, Monica] Haut Dermatol, Brisbane, Qld, Australia.
   [Chaboyer, Wendy P.] Griffith Univ, Sch Nursing & Midwifery, Brisbane, Qld, Australia.
C3 Menzies Health Institute Queensland; Griffith University; University of
   Queensland; Royal Brisbane & Women's Hospital; Sichuan University;
   University of Manchester; University of Manchester; Manchester
   University NHS Foundation Trust; Griffith University; Griffith
   University
RP Webster, J (通讯作者)，Royal Brisbane & Womens Hosp, Nursing & Midwifery Res Ctr, Butterfield St, Herston, Qld 4029, Australia.
EM joan.webster@health.qld.gov.au
RI Scuffham, Paul/B-3066-2014; Chaboyer, Wendy/F-9588-2018; Liu,
   Zhenmi/O-7046-2014; Norman, Gill/O-7029-2014; Dumville, Jo/O-7867-2014
OI Scuffham, Paul/0000-0001-5931-642X; Chaboyer, Wendy/0000-0001-9528-7814;
   Stankiewicz, Monica/0000-0003-3970-071X; Norman,
   Gill/0000-0002-3972-5733; Dumville, Jo/0000-0002-6546-3685
FU Royal Brisbane and Women's Hospital, Australia; Division of Nursing,
   Midwifery and Social Work, School of Health Sciences, Faculty of
   Biology, Medicine and Health, University of Manchester, UK; National
   Institute for Health Research (NIHR), UK; National Institute for Health
   Research, via Cochrane Infrastructure; National Institute for Health
   Research (NIHR) Systematic Review Fellowships, UK [NIHR-RMFI-2015-06-52
   Zhenmi Liu]; National Institute for Health Research Collaboration for
   Leadership in Applied Health Research and Care (NIHR CLAHRC) Greater
   Manchester Centre, UK; National Institute for Health Research
   Collaboration for Leadership in Applied Health Research and Care (NIHR
   CLAHRC) Greater Manchester; NIHR Manchester Biomedical Research Centre,
   UK; NIHR Manchester Biomedical Research Centre; Cochrane Programme Grant
   funding (NIHR Cochrane Programme Grant) [13/89/08]; Griffith University,
   Australia; National Institute for Health Research [13/89/08] Funding
   Source: researchfish
FX Internal sourcesRoyal Brisbane and Women's Hospital, Australia.Time to
   conduct reviewGriffith University, Australia.Time to conduct
   reviewDivision of Nursing, Midwifery and Social Work, School of Health
   Sciences, Faculty of Biology, Medicine and Health, University of
   Manchester, UK.External sourcesThe National Institute for Health
   Research (NIHR), UK.This project was supported by the National Institute
   for Health Research, via Cochrane Infrastructure and Cochrane Programme
   Grant funding (NIHR Cochrane Programme Grant 13/89/08 - High Priority
   Cochrane Reviews in Wound Prevention and Treatment) to Cochrane Wounds.
   The views expressed are those of the authors and not necessarily those
   of the NIHR or the Department of Health and Social Care.National
   Institute for Health Research (NIHR) Systematic Review Fellowships
   (NIHR-RMFI-2015-06-52 Zhenmi Liu), UK.National Institute for Health
   Research Collaboration for Leadership in Applied Health Research and
   Care (NIHR CLAHRC) Greater Manchester Centre, UK.Jo Dumville was partly
   funded by the National Institute for Health Research Collaboration for
   Leadership in Applied Health Research and Care (NIHR CLAHRC) Greater
   Manchester. The funder had no role in the design of the studies, data
   collection and analysis, decision to publish, or preparation of the
   manuscript. However, the review may be considered to be affiliated to
   the work of the NIHR CLAHRC Greater Manchester. The views expressed
   herein are those of the authors and not necessarily those of the NHS,
   NIHR or the Department of Health and Social Care.NIHR Manchester
   Biomedical Research Centre, UK.This review was co-funded by the NIHR
   Manchester Biomedical Research Centre. The views expressed in this
   publication are those of the author(s) and not necessarily those of the
   NHS, the National Institute for Health Research or the Department of
   Health and Social Care.
CR ABS, 2014, 31010 ABS
   Acosta S, 2017, BJS-BRIT J SURG, V104, pE75, DOI 10.1002/bjs.10403
   Al-Inany H, 2002, GYNECOL OBSTET INVES, V53, P75, DOI 10.1159/000052996
   Albert NM, 2012, J WOUND OSTOMY CONT, V39, P259, DOI 10.1097/WON.0b013e3182487a50
   Althumairi AA, 2016, COLORECTAL DIS, V18, pO260, DOI 10.1111/codi.13384
   Anderson V, 2014, EVID BASED MIDWIFERY, V12, P23
   Andersson AE, 2010, AM J INFECT CONTROL, V38, P711, DOI 10.1016/j.ajic.2010.03.017
   [Anonymous], COCHRANE HDB SYSTEMA
   [Anonymous], Interpreting results and drawing conclusions | Cochrane Training
   [Anonymous], 2 WORLD UN WOUND HEA
   [Anonymous], 2 WORLD UN WOUND HEA
   Apostoli Alberto, 2008, Prof Inferm, V61, P158
   Banasiewicz Tomasz, 2013, Pol Przegl Chir, V85, P371, DOI 10.2478/pjs-2013-0056
   Banwell P E, 2003, J Wound Care, V12, P22
   Baronski S., 2008, Wound Care Essentials Principles and Practice
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Blume PA, 2010, INT WOUND J, V7, P480, DOI 10.1111/j.1742-481X.2010.00728.x
   Bondokji S, 2011, J WOUND CARE, V20, P62, DOI 10.12968/jowc.2011.20.2.72
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   Brazier JE, 2004, MED CARE, V42, P851, DOI 10.1097/01.mlr.0000135827.18610.0d
   Carter MR, 2016, IRISH J MED SCI, V185, pS111
   Chaboyer W, 2014, HEALTHCARE, V2, P417, DOI 10.3390/healthcare2040417
   Chen DZ, 2017, J CELL MOL MED, V21, P1513, DOI 10.1111/jcmm.13080
   Chiang N, 2017, J VASC SURG, V66, P564, DOI 10.1016/j.jvs.2017.02.050
   Chio EG, 2010, OTOLARYNG HEAD NECK, V142, P174, DOI 10.1016/j.otohns.2009.11.003
   Citak M, 2010, ARCH ORTHOP TRAUM SU, V130, P1511, DOI 10.1007/s00402-010-1091-6
   Coulthard P, 2010, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004287.pub3
   Craig BM, 2013, MED DECIS MAKING, V33, P793, DOI 10.1177/0272989X13482524
   Crist BD, 2014, ORTH TRAUM ASS ANN M, P270
   Crist BD, 2017, INJURY, V48, P1518, DOI 10.1016/j.injury.2017.04.055
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   DeCarbo WT, 2010, J FOOT ANKLE SURG, V49, P299, DOI 10.1053/j.jfas.2010.01.002
   DiMuzio P, 2017, J VASC SURG, V65, p133S, DOI 10.1016/j.jvs.2017.03.250
   Dorafshar AH, 2012, ANN PLAS SURG, V69, P79, DOI 10.1097/SAP.0b013e318221286c
   Dragu A, 2011, OBES SURG, V21, P1781, DOI 10.1007/s11695-010-0328-3
   Drummond MichaelF., 2002, Methods for the Economic Evaluation of Health Care Programmes
   Dumville JC, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011226.pub2
   Eisenhardt SU, 2012, J PLAST RECONSTR AES, V65, P640, DOI 10.1016/j.bjps.2011.11.037
   Eneroth M, 2008, DIABETES-METAB RES, V24, pS76, DOI 10.1002/dmrr.852
   Engelhardt M, 2018, INT WOUND J, V15, P327, DOI 10.1111/iwj.12848
   Fleischmann W, 1997, UNFALLCHIRURG, V100, P301, DOI 10.1007/s001130050123
   Frazee R, 2018, J AM COLL SURGEONS, V226, P507, DOI 10.1016/j.jamcollsurg.2017.12.008
   Furukawa TA, 2006, J CLIN EPIDEMIOL, V59, P7, DOI 10.1016/j.jclinepi.2005.06.006
   Gabriel Allen, 2014, Surg Technol Int, V24, P75
   Gabriel Allen, 2011, Plast Surg Nurs, V31, P65, DOI 10.1097/PSN.0b013e318219778b
   Garrison KR, 2010, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006950.pub2
   Gillespie BM, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2015-010287
   Gillespie BM, 2015, SURG INNOV, V22, P488, DOI 10.1177/1553350615573583
   Grauhan O, 2013, J THORAC CARDIOV SUR, V145, P1387, DOI 10.1016/j.jtcvs.2012.09.040
   Gregor S, 2008, ARCH SURG-CHICAGO, V143, P189, DOI 10.1001/archsurg.2007.54
   Gunatilake RP, 2017, AJP REP, V7, pE151, DOI 10.1055/s-0037-1603956
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Gurtner GC, 2008, NATURE, V453, P314, DOI 10.1038/nature07039
   Heard C, 2017, J TISSUE VIABILITY, V26, P79, DOI 10.1016/j.jtv.2016.06.001
   Heuser M, 2005, J Wound Care, V14, P406
   Higgins J., 2011, COCHRANE COLLABORATI, DOI [DOI 10.2105/AJPH.2020.305609, DOI 10.1002/14651858.CD001930.PUB3]
   Hope SF, 2017, PLOS ONE, V12, DOI 10.1371/journal.pone.0173600
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   HU Kai-xuan, 2009, Zhonghua Shao Shang Za Zhi, V25, P253
   Hurd T, 2014, OSTOMY WOUND MANAG, V60, P30
   Husereau D, 2013, INT J TECHNOL ASSESS, V29, P117, DOI 10.1017/S0266462313000160
   Hussamy DJ, 2018, AM J OBSTET GYNECOL, V218, pS35, DOI 10.1016/j.ajog.2017.10.456
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Ingargiola Michael J, 2013, Eplasty, V13, pe49
   Johannesson A, 2008, ACTA ORTHOP, V79, P361, DOI 10.1080/17453670710015265
   Kairinos N, 2014, PLAST RECONSTR SURG, V133, P1178, DOI 10.1097/PRS.0000000000000130
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P601, DOI 10.1097/PRS.0b013e318196b97b
   Kanakaris NK, 2007, INJURY, V38, pS9, DOI 10.1016/j.injury.2007.10.029
   Kantak NA, 2016, BURNS, V42, P1623, DOI 10.1016/j.burns.2016.06.011
   Karabacak E, 2016, INT WOUND J, V13, P289, DOI 10.1111/iwj.12232
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Kenig Jakub, 2012, Pol Przegl Chir, V84, P565, DOI 10.2478/v10035-012-0094-0
   Keskin M, 2008, SCAND J PLAST RECONS, V42, P202, DOI 10.1080/02844310802091586
   Kharroubi SA, 2007, J HEALTH ECON, V26, P597, DOI 10.1016/j.jhealeco.2006.09.002
   Kim EK, 2007, ANN PLAS SURG, V58, P536, DOI 10.1097/01.sap.0000245121.32831.47
   Kloth Luther C, 2002, Adv Skin Wound Care, V15, P226, DOI 10.1097/00129334-200209000-00008
   Kuncewitch M, 2017, GASTROENTEROLOGY, V152, pS1273, DOI 10.1016/S0016-5085(17)34243-9
   Lancet Commission on Global Surgery, NUMB SURG PROC PER 1
   Lee AJ, 2017, INTERACT CARDIOV TH, V24, P324, DOI 10.1093/icvts/ivw400
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Leon M, 2016, COLORECTAL DIS S1, V18, P7, DOI DOI 10.1111/CODI.13441
   Lesaffre E, 2009, STAT MED, V28, P3470, DOI 10.1002/sim.3634
   Li PY, 2016, SCANDANAVIAN J SURG, V106, P189
   Llanos S, 2006, ANN SURG, V244, P700, DOI 10.1097/01.sla.0000217745.56657.e5
   Lozano-Balderas G, 2017, AM SURGEON, V83, P512
   Maehara Y, 2017, SURG TODAY, V47, P1060, DOI 10.1007/s00595-017-1480-3
   Mandal A, 2007, J Wound Care, V16, P33
   Manoharan V, 2016, J ARTHROPLASTY, V31, P2487, DOI 10.1016/j.arth.2016.04.016
   Masden D, 2012, ANN SURG, V255, P1043, DOI 10.1097/SLA.0b013e3182501bae
   Moisidis E, 2004, PLAST RECONSTR SURG, V114, P917, DOI 10.1097/01.PRS.0000133168.57199.E1
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Mouës CM, 2007, J PLAST RECONSTR AES, V60, P672, DOI 10.1016/j.bjps.2006.01.041
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Moues CM, 2003, 13 C EUR WOUND MAN A, P69, DOI DOI 10.1097/01.PRS.0000133168.57199.E1
   Mullins A, 2012, VALUE HEALTH, V15, pA68, DOI 10.1016/j.jval.2012.03.374
   National Institute for Health and Care Excellence (NICE), QUAL ADJ LIF YEAR QA
   Nguyen V, 2017, SURG ENDOSC S, V31, pS226
   Nherera LM, 2017, WOUND REPAIR REGEN, V25, P474, DOI 10.1111/wrr.12530
   NICE, 2013, JUDG WHETHER PUBL HL
   Nordic Cochrane Centre The Cochrane Collaboration, 2014, REV MAN 5 REVMAN 5 V
   Nordmeyer M, 2016, INT WOUND J, V13, P1176, DOI 10.1111/iwj.12436
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Olbrecht VA, 2006, ANN THORAC SURG, V82, P902, DOI 10.1016/j.athoracsur.2006.04.058
   Ousey Karen J, 2014, Br J Community Nurs, VSuppl, pS16
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Pauser J, 2016, INT WOUND J, V13, P663, DOI 10.1111/iwj.12344
   Pellino G, 2015, UPDATES SURG, V67, P235, DOI 10.1007/s13304-015-0298-z
   Pellino G, 2014, SURG INNOV, V21, P204, DOI 10.1177/1553350613496906
   Petkar K, 2012, EUR J PLAST SURG, V35, P579, DOI 10.1007/s00238-012-0698-y
   Petzina R, 2010, J THORAC CARDIOV SUR, V140, P1133, DOI 10.1016/j.jtcvs.2010.06.063
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Rahmanian-Schwarz A, 2012, BURNS, V38, P573, DOI 10.1016/j.burns.2011.10.010
   Rodero MP, 2010, INT J CLIN EXP PATHO, V3, P643
   Ruhstaller K, 2017, AM J OBSTET GYNECOL, V216, pS34, DOI 10.1016/j.ajog.2016.11.017
   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
   Sabat J, 2016, J VASC SURG, V63, p94S, DOI 10.1016/j.jvs.2016.03.099
   Sandy-Hodgetts K, 2015, INT WOUND J, V12, P265, DOI 10.1111/iwj.12088
   Shemilt I, 2010, EVID POLICY, V6, P51, DOI 10.1332/174426410X482999
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Shmueli A, 1999, MED DECIS MAKING, V19, P122, DOI 10.1177/0272989X9901900202
   Sjögren J, 2011, INTERACT CARDIOV TH, V12, P117, DOI 10.1510/icvts.2010.252668
   Stand-Up MRI of Deer Park P. C. North Babylon NY USA, NON TRADITIONAL REF
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Statistics Finland, 2015, NON TRADITIONAL REF
   Steenvoorde P, 2009, OSTOMY WOUND MANAG, V55, P44
   Stevens P, 2009, INT WOUND J, V6, P259, DOI 10.1111/j.1742-481X.2009.00614.x
   SUNRRISE study group, 2017, COLORECTAL DIS S2, V19, P14
   Tanaka T, 2016, EUR J PLAST SURG, V39, P247, DOI 10.1007/s00238-016-1200-z
   Tanaydin V, 2018, AESTHET PLAST SURG, V42, P927, DOI 10.1007/s00266-018-1095-0
   The Campbell and Cochrane Economics Methods Group (CCEMG) and the Evidence for Policy and Practice Information and Coordinating Centre (EPPI Centre), CCEMG-EPPI-Centre Cost Converter v.1.4
   Toeg H, 2017, J THORAC CARDIOV SUR, V153, P1394, DOI 10.1016/j.jtcvs.2016.11.040
   Tuffaha HW, 2015, J SURG RES, V195, P612, DOI 10.1016/j.jss.2015.02.008
   Tuuli MG, 2017, AM J OBSTET GYNECOL, V216, pS245, DOI 10.1016/j.ajog.2016.11.670
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   US Food and Drug Administration (FDA), 2009, SER COMPL ASS NEG PR
   US Food Drug Administration (FDA), 2009, NEG PRESS WOUND DEV
   Vikatmaa P, 2008, EUR J VASC ENDOVASC, V36, P438, DOI 10.1016/j.ejvs.2008.06.010
   Visser R, 2017, J PEDIATR SURG, V52, P849, DOI 10.1016/j.jpedsurg.2017.01.035
   Waisbren E, 2010, J AM COLL SURGEONS, V210, P381, DOI 10.1016/j.jamcollsurg.2010.01.004
   Webb LX, 2017, ORTHOP CLIN N AM, V48, P167, DOI 10.1016/j.ocl.2016.12.004
   Webster J, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006620.pub5
   Webster J, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub3
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Winfield RD, 2016, AM SURGEON, V82, P331
   Witt-Majchrzak Anna, 2015, Pol Przegl Chir, V86, P456, DOI [10.2478/pjs-2014-0082, 10.2478/pjs-2014-0082]
   World Health Organization (WHO), 2016, PROPH NEG PRESS WOUN
   Xia CY, 2014, MOL MED REP, V9, P1749, DOI 10.3892/mmr.2014.1997
   Yu YC, 2017, MEDICINE, V96, DOI 10.1097/MD.0000000000005925
   2008, INT WOUND J S4, V5, P1
NR 153
TC 127
Z9 144
U1 2
U2 31
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1469-493X
EI 1361-6137
J9 COCHRANE DB SYST REV
JI Cochrane Database Syst Rev.
PY 2019
IS 3
AR CD009261
DI 10.1002/14651858.CD009261.pub4
PG 170
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA HR1ZM
UT WOS:000462935200046
PM 30912582
OA Green Submitted, Green Published, Bronze
DA 2026-07-24
ER

PT J
AU Strowitzki, M
   Vastmans, J
   Vogel, M
   Jaksche, H
AF Strowitzki, Martin
   Vastmans, Jan
   Vogel, Matthias
   Jaksche, Hans
TI Complex 360°-reconstruction and stabilization of the cervical spine due
   to osteomyelitis
SO EUROPEAN SPINE JOURNAL
LA English
DT Article
DE Vertebral osteomyelitis; Spondylodiscitis; Cervical reconstruction
ID SURGICAL-MANAGEMENT; SPONDYLODISCITIS; ANTERIOR; FUSION;
   INSTRUMENTATION; DEBRIDEMENT; FIXATION; CAGES
AB Osteomyelitis of the cervical spine may lead to profound bony destruction. The presented case developed multilevel osteomyelitic destruction of the cervical spine after decompression due to cervical myelopathy. He could be cured by a multiple-stage procedure: step one: debridement and removal of all anterior implants with vacuum-assisted closure combined with dorsal instrumentation from C0 to T3; step two: anterior reconstruction with expandable titanium cages and plate. The patient regained walking with the aid of a walking frame. The following recommendations are given: multiple stage procedure, extensive debridement and stabilization via an anterior and posterior approach, use of titanium implants.
C1 [Strowitzki, Martin; Jaksche, Hans] Trauma Ctr Murnau, Dept Neurosurg, D-82418 Murnau, Germany.
   [Vastmans, Jan; Vogel, Matthias] Trauma Ctr Murnau, Dept Spinal Cord Injuries, D-82418 Murnau, Germany.
RP Strowitzki, M (通讯作者)，Trauma Ctr Murnau, Dept Neurosurg, Prof Kuntscher Str 8, D-82418 Murnau, Germany.
EM martin.strowitzki@bgu-murnau.de
CR ACOSTA FJR, 2004, FOCUS, V17, pE2
   Barnes Bryan, 2004, Neurosurg Focus, V17, pE11
   Bose B, 1998, SURG NEUROL, V49, P25, DOI 10.1016/S0090-3019(97)00306-6
   CASPAR W, 1989, NEUROSURGERY, V25, P491, DOI 10.1227/00006123-198910000-00001
   CLOWARD R B, 1978, Spine, V3, P194, DOI 10.1097/00007632-197809000-00002
   Eysel P, 1997, Eur Spine J, V6, P152, DOI 10.1007/BF01301428
   Fayazi Amir H, 2004, Spine J, V4, P388, DOI 10.1016/j.spinee.2004.01.004
   Frangen TM, 2006, UNFALLCHIRURG, V109, P743, DOI 10.1007/s00113-006-1084-7
   Ghanayem AJ, 1996, ORTHOP CLIN N AM, V27, P53
   Heyde CE, 2006, EUR SPINE J, V15, P1380, DOI 10.1007/s00586-006-0191-z
   Isenberg J, 2005, ORTHOPADE, V34, P159, DOI 10.1007/s00132-004-0722-4
   JEANNERET B, 1994, J SPINAL DISORD, V7, P185, DOI 10.1097/00002517-199407030-00001
   Klöckner C, 2001, ORTHOPADE, V30, P965, DOI 10.1007/s001320170010
   Korovessis P, 2006, SPINE, V31, P1014, DOI 10.1097/01.brs.0000215049.08622.9d
   Korovessis P, 2008, SPINE, V33, P759, DOI DOI 10.1097/BRS.0B013E318187875E
   Korovessis P, 2006, CLIN ORTHOP RELAT R, P51, DOI 10.1097/01.blo.0000203449.51769.7f
   Lee Max C, 2004, Neurosurg Focus, V17, pE7
   Lerner T, 2005, Z ORTHOP GRENZGEB, V143, P204, DOI 10.1055/s-2005-836455
   Liljenqvist U, 2003, EUR SPINE J, V12, P606, DOI 10.1007/s00586-003-0614-z
   Linhardt O, 2004, Z ORTHOP GRENZGEB, V142, P73, DOI 10.1055/s-2004-818031
   Ogden Alfred T, 2004, Neurosurg Focus, V17, pE5
   Pee YH, 2008, J NEUROSURG-SPINE, V8, P405, DOI 10.3171/SPI/2008/8/5/405
   Przybylski GJ, 2001, J NEUROSURG, V94, P1, DOI 10.3171/spi.2001.94.1.0001
   Ruf M, 2007, SPINE, V32, pE275, DOI 10.1097/01.brs.0000261034.83395.7f
   Schimmer RC, 2002, J SPINAL DISORD TECH, V15, P110, DOI 10.1097/00024720-200204000-00004
   Schinkel Christian, 2003, Surg Infect (Larchmt), V4, P387, DOI 10.1089/109629603322761445
   Suess O, 2007, ZBL NEUROCHIR, V68, P123, DOI 10.1055/s-2007-984461
   YANG EC, 1988, CLIN ORTHOP RELAT R, P229
NR 28
TC 6
Z9 7
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0940-6719
EI 1432-0932
J9 EUR SPINE J
JI Eur. Spine J.
PD JUL
PY 2011
VL 20
SU 2
BP S248
EP S252
DI 10.1007/s00586-010-1645-x
PG 5
WC Clinical Neurology; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Orthopedics
GA 811OM
UT WOS:000294221200025
PM 21116660
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU McNamara, SA
   Hirt, PA
   Weigelt, MA
   Nanda, S
   de Bedout, V
   Kirsner, RS
   Schachner, LA
AF McNamara, Stephanie A.
   Hirt, Penelope A.
   Weigelt, Maximillian A.
   Nanda, Sonali
   de Bedout, Valeria
   Kirsner, Robert S.
   Schachner, Lawrence A.
TI Traditional and advanced therapeutic modalities for wounds in the
   paediatric population: an evidence-based review
SO JOURNAL OF WOUND CARE
LA English
DT Review
DE antibiotics; dressings; epidermolysis bullosa; matrices; paediatric
   wounds; pressure ulcers
ID AMNION/CHORION MEMBRANE ALLOGRAFTS; DERMAL REGENERATION TEMPLATE;
   PRESSURE ULCER PREVALENCE; SURGICAL SITE INFECTIONS; INTEGRA ARTIFICIAL
   SKIN; VACUUM-ASSISTED CLOSURE; EPIDERMOLYSIS-BULLOSA; HYDROSURGERY
   SYSTEM; TOPICAL TIMOLOL; PYODERMA-GANGRENOSUM
AB Objective: Children can have non-healing wounds due to a wide range of pathologies, including epidermolysis bullosa (EB), pilonidal disease and Stevens-Johnson syndrome, with some causes being iatrogenic, including extravasation injuries and medical devicerelated hospital-acquired pressure ulcers. Furthermore, paediatric wounds are vastly different from adult wounds and therefore require a different treatment approach. While there are numerous types of dressings, topical remedies, and matrices with high-tier evidence to support their use in adults, evidence is scarce in the neonatal and paediatric age groups. The purpose of this review is to discuss the basic principles in paediatric wound management, as well as to present new treatment findings published in the literature to date.The benefits and risks of using different types of debridement are discussed in this review. Various topical formulations are also described, including the need to use antibiotics judiciously.
   Method: Databases were searched for relevant sources including Pubmed, Embase, Web of Science and DynaMed. Search terms used included 'wound care', 'wound management', 'paediatrics', 'children', 'skin substitutes', and 'grafts'. Additionally, each treatment and disease entity was searched for relevant sources, including, for example: 'Apligraf', 'dermagraft', 'Manuka honey', 'antibiotic', 'timolol', and 'negative pressure wound therapy' (NPWT).
   Results: Amniotic membrane living skin equivalent is a cellular matrix that has been reportedly successful in treating paediatrics wounds and is currently under investigation in randomised clinical trials. Helicoll is an acellular matrix, which shows promise in children with recessive dystrophic EB. NPWT may be used as a tool to accelerate wound closure in children; however, caution must be taken due to limited evidence to support its safety and efficacy in the paediatric patient population. Integra has been reported as a useful adjunctive treatment to NPWT as both may act synergistically. Hospitalised children and neonates frequently have pressure ulcers, which is why prevention in this type of wound is paramount.
   Conclusion: Advancements in wound care are rapidly expanding. Various treatments for non-healing wounds in paediatric and neonatal patients have been reported, but high tier evidence in these populations is scarce. We hope to shed light on existing evidence regarding the different therapeutic modalities, from debridement techniques and dressing types to tissue substitutes and topical remedies. There have been promising results in many studies to date, but RCTs involving larger sample sizes are necessary, in order to determine the specific role these innovative agents play in paediatric wounds and to identify true safety and efficacy.
C1 [McNamara, Stephanie A.; Hirt, Penelope A.; Weigelt, Maximillian A.; Nanda, Sonali; de Bedout, Valeria; Kirsner, Robert S.; Schachner, Lawrence A.] Univ Miami, Miller Sch Med, Dr Phillip Frost Dermatol & Cutaneous Surg, 1321 NW 14th St,Suite 506, Miami, FL 33125 USA.
C3 University of Miami
RP McNamara, SA (通讯作者)，Univ Miami, Miller Sch Med, Dr Phillip Frost Dermatol & Cutaneous Surg, 1321 NW 14th St,Suite 506, Miami, FL 33125 USA.
EM s.mlacker@umiami.edu
RI Weigelt, Maximillian/LTD-8183-2024
CR Amaya R, 2015, J WOUND CARE, V24, P95, DOI 10.12968/jowc.2015.24.3.95
   [Anonymous], 1996, Ann. Burns Fire Disasters
   [Anonymous], 2002, HEART VIEWS
   [Anonymous], 2019, WOUND DEBRIDEMENT
   Bacik Lindsay, 2018, JAAD Case Rep, V4, P890, DOI [10.1016/j.jdcr.2018.01.013, 10.1016/j.jdcr.2018.01.013]
   Baharestani M, 2009, INT WOUND J, V6, P1, DOI 10.1111/j.1742-481X.2009.00607.x
   Baharestani MM, 2007, OSTOMY WOUND MANAG, V53, P34
   Baldwin Kathleen M, 2002, Adv Skin Wound Care, V15, P121, DOI 10.1097/00129334-200205000-00007
   Bannasch H, 2004, ARCH DERMATOL, V140, P160, DOI 10.1001/archderm.140.2.160
   Bell SG, 2007, NEONATAL NETW, V26, P247, DOI 10.1891/0730-0832.26.4.247
   Berhane CC, 2019, J WOUND CARE, V28, pS4, DOI 10.12968/jowc.2019.28.Sup5.S4
   Besner GE, 1998, J BURN CARE REHABIL, V19, P324, DOI 10.1097/00004630-199807000-00010
   Biglari B, 2013, INT WOUND J, V10, P252, DOI 10.1111/j.1742-481X.2012.00970.x
   Birdsong M, 2014, J PEDIAT SURG NURS, V3, P60, DOI [10.1097/JPS.0000000000000021, DOI 10.1097/JPS.0000000000000021]
   Bittmann Stefan, 2010, Br J Nurs, V19, pS19
   Black KD, 2015, PEDIATR REV, V36, P207, DOI 10.1542/pir.36-5-207
   Blanchet-Bardon C, 2005, J Wound Care, V14, P490
   Blanchet-Bardon C, 2005, J WOUND CARE, V14, P494
   Block L, 2015, ADV WOUND CARE, V4, P596, DOI 10.1089/wound.2015.0640
   Bluestein D, 2008, AM FAM PHYSICIAN, V78, P1186
   Blume-Peytavi U, 2012, PEDIATR DERMATOL, V29, P1, DOI 10.1111/j.1525-1470.2011.01594.x
   Boesch RP, 2012, PEDIATRICS, V129, pE792, DOI 10.1542/peds.2011-0649
   Bohaty Benjamin R, 2015, Int J Womens Dermatol, V1, P13, DOI [10.1016/j.ijwd.2014.12.002, 10.1016/j.ijwd.2014.12.002]
   Bolognia J., 2012, Fig
   Boyar V, 2014, J PERINATOL, V34, P161, DOI 10.1038/jp.2013.158
   Boyar Vita, 2018, Ostomy Wound Manage, V64, P22, DOI 10.25270/owm.2018.11.2228
   Boyar V, 2018, WOUNDS, V30, P224
   Boyar V, 2018, J WOUND OSTOMY CONT, V45, P117, DOI 10.1097/WON.0000000000000407
   Boyar V, 2016, J WOUND OSTOMY CONT, V43, P547, DOI 10.1097/WON.0000000000000266
   Branski LK, 2008, BURNS, V34, P393, DOI 10.1016/j.burns.2007.06.007
   Broom M, 2019, HEALTH SERV INSIGHTS, V12, DOI 10.1177/1178632919845630
   Browning P, 2016, J WOUND CARE, V25, P452, DOI 10.12968/jowc.2016.25.8.452
   Buganza TepoleA., 2013, Pediatric Res, V73, P553, DOI DOI 10.1038/PR.2013.3)
   BURCH RM, 1991, AGENTS ACTIONS, V34, P229, DOI 10.1007/BF01993288
   Bütter A, 2006, J PEDIATR SURG, V41, P940, DOI 10.1016/j.jpedsurg.2006.01.061
   Cairo SB, 2019, J WOUND CARE, V28, pS12, DOI 10.12968/jowc.2019.28.Sup5.S12
   Canton R, 2018, FUTURE MICROBIOL, V13, DOI 10.2217/fmb-2017-0289
   Charles CA, 2004, DERMATOL SURG, V30, P1236, DOI 10.1111/j.1524-4725.2004.30383.x
   Chiaverini C, 2016, J AM ACAD DERMATOL, V75, pE223, DOI 10.1016/j.jaad.2016.08.005
   Choo J, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011331
   Cisler-Cahill L, 2006, NEONATAL NETW, V25, P267, DOI 10.1891/0730-0832.25.4.267
   Clements KE, 2016, J PEDIATR SURG, V51, P1405, DOI 10.1016/j.jpedsurg.2016.04.002
   Costeloe A, 2018, INT J PEDIATR OTORHI, V111, P80, DOI 10.1016/j.ijporl.2018.05.026
   Cubison TCS, 2006, BURNS, V32, P714, DOI 10.1016/j.burns.2006.01.023
   Cummins KA, 2019, NURS CLIN N AM, V54, P127, DOI 10.1016/j.cnur.2018.10.005
   Curley Martha A Q, 2003, Pediatr Crit Care Med, V4, P284, DOI 10.1097/01.PCC.0000075559.55920.36
   Curley MAQ, 2018, J PEDIATR-US, V192, P189, DOI 10.1016/j.jpeds.2017.09.045
   de Haas LEM, 2019, J CRANIOFAC SURG, V30, P888, DOI 10.1097/SCS.0000000000005375
   de Jesus LE, 2018, J PEDIATR SURG, V53, P585, DOI 10.1016/j.jpedsurg.2017.11.048
   Denyer J, 2015, J WOUND CARE, V24, P446, DOI 10.12968/jowc.2015.24.10.446
   Dixon M, 2005, OSTOMY WOUND MANAG, V51, P44
   Dorman RM, 2016, PEDIATR SURG INT, V32, P997, DOI 10.1007/s00383-016-3915-0
   Drosou A, 2005, J AM ACAD DERMATOL, V52, P854, DOI 10.1016/j.jaad.2004.11.069
   Duque-Estrada EO, 2003, PEDIATR SURG INT, V19, P436, DOI 10.1007/s00383-002-0735-1
   Durante CM, 2014, MINERVA CHIR, V69, P283
   Elsass Ferne T, 2017, Wounds, V29, pE115
   Falabella AF, 2000, ARCH DERMATOL, V136, P1225, DOI 10.1001/archderm.136.10.1225
   Forbes Thomas A, 2016, Perit Dial Int, V36, P684, DOI 10.3747/pdi.2014.00350
   Frommelt P, 2016, PEDIATR DERMATOL, V33, P405, DOI 10.1111/pde.12869
   Fu XB, 2001, WOUND REPAIR REGEN, V9, P2, DOI 10.1046/j.1524-475x.2001.00002.x
   Fuzaylov G, 2009, PEDIATR ANESTH, V19, P202, DOI 10.1111/j.1460-9592.2009.02924.x
   Gannon Barbara A, 2004, Neonatal Netw, V23, P25
   García-Molina P, 2018, INT WOUND J, V15, P571, DOI 10.1111/iwj.12900
   Garoufalis M, 2018, J AM PODIAT MED ASSN, V108, P84, DOI 10.7547/17-039
   Gelmetti A, 2018, TRANSFUS APHER SCI, V57, P370, DOI 10.1016/j.transci.2018.05.021
   Gorell ES, 2015, PEDIATR DERMATOL, V32, P220, DOI 10.1111/pde.12492
   Grando SA, 2006, J INVEST DERMATOL, V126, P1948, DOI 10.1038/sj.jid.5700151
   Greenwood John E, 2011, Eplasty, V11, pe10
   Han G, 2017, ADV THER, V34, P599, DOI 10.1007/s12325-017-0478-y
   Harper HE, 2022, J DERMATOL TREAT, V33, P48, DOI 10.1080/09546634.2020.1743812
   HAYASHI AH, 1991, J PEDIATR SURG, V26, P1279, DOI 10.1016/0022-3468(91)90598-N
   Hebert AA, 2018, J DRUGS DERMATOL, V17, P1051
   Heimall LM, 2012, MCN-AM J MATERN-CHIL, V37, P10, DOI 10.1097/NMC.0b013e31823850ea
   Herlin C, 2007, J HAND SURG-BRIT EUR, V32E, P179, DOI 10.1016/j.jhsb.2006.11.013
   Hirt PA, 2019, BRIT J DERMATOL, V181, P393, DOI 10.1111/bjd.17682
   Horwitz JR, 1998, ANN SURG, V227, P553, DOI 10.1097/00000658-199804000-00017
   Housinger Terry A., 1993, Journal of Burn Care and Rehabilitation, V14, P26, DOI 10.1097/00004630-199301000-00007
   Hübner NO, 2010, SKIN PHARMACOL PHYS, V23, P17, DOI 10.1159/000318264
   Hutchison RL, 2013, J WOUND CARE, V22, P708, DOI 10.12968/jowc.2013.22.12.708
   Jadotte YT, 2012, J AM ACAD DERMATOL, V66, P187, DOI 10.1016/j.jaad.2011.09.039
   Johnson A, 1992, Ostomy Wound Manage, V38, P36
   Jull AB, 2008, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD005083.pub2
   Kapila AK, 2019, ADV SKIN WOUND CARE, V32, P1, DOI 10.1097/01.ASW.0000580480.86585.3a
   Kechichian E, 2017, INT J DERMATOL, V56, P486, DOI 10.1111/ijd.13584
   Khadra C, 2018, J PAIN RES, V11, P343, DOI 10.2147/JPR.S151084
   Kim PJ, 2018, WOUNDS, V30, P114
   Kimble RM, 2008, BURNS, V34, P297, DOI 10.1016/j.burns.2007.08.018
   King A, 2014, ADV WOUND CARE, V3, P324, DOI 10.1089/wound.2013.0477
   Kirsner RS, 2019, J WOUND CARE, V28, P398, DOI 10.12968/jowc.2019.28.6.398
   Kirsner RS, 2012, ADV SKIN WOUND CARE, V25, P400, DOI 10.1097/01.ASW.0000419404.44947.de
   Kriesberg CP, 2018, J WOUND OSTOMY CONT, V45, P497, DOI 10.1097/WON.0000000000000477
   Kugelman A, 2008, PEDIATRICS, V122, P550, DOI 10.1542/peds.2007-2729
   Lejus C, 2013, J PEDIATR SURG, V48, P1503, DOI 10.1016/j.jpedsurg.2013.01.055
   Letouze A, 2004, J Wound Care, V13, P221
   Levy A, 2017, J TISSUE VIABILITY, V26, P57, DOI 10.1016/j.jtv.2016.02.002
   Lintzeris D, 2018, WOUNDS, V30, P72
   Lo V, 2010, J AM ACAD DERMATOL, V62, P1038, DOI 10.1016/j.jaad.2009.02.048
   Lopez G, 2008, J PEDIATR SURG, V43, P2202, DOI 10.1016/j.jpedsurg.2008.08.067
   Mahabbat Nehal, 2018, Eplasty, V18, pe30
   Marini I, 2001, J PERIODONTOL, V72, P691, DOI 10.1902/jop.2001.72.5.691
   Mathias Elton, 2017, Medicines (Basel), V4, DOI [10.3390/medicines4040091, 10.3390/medicines4040091]
   McCallon Stanley K, 2014, J Am Coll Clin Wound Spec, V6, P14, DOI 10.1016/j.jccw.2015.08.003
   McNeil JC, 2014, ANTIMICROB AGENTS CH, V58, P2878, DOI 10.1128/AAC.02707-13
   Meuli M, 2019, PLAST RECONSTR SURG, V144, P188, DOI 10.1097/PRS.0000000000005746
   Min JH, 2014, ARCH PLAST SURG-APS, V41, P330, DOI 10.5999/aps.2014.41.4.330
   Mohr LD, 2014, J WOUND OSTOMY CONT, V41, P213, DOI 10.1097/WON.0000000000000028
   Morris Clare, 2009, Paediatr Nurs, V21, P38
   Murray JS, 2013, J PEDIATR NURS, V28, P585, DOI 10.1016/j.pedn.2013.05.004
   Nenoff P, 2010, WIEN MED WOCHENSCHR, V160, P578, DOI 10.1007/s10354-010-0806-1
   Nikolovski J, 2008, J INVEST DERMATOL, V128, P1728, DOI 10.1038/sj.jid.5701239
   Noonan Catherine, 2006, J Pediatr Nurs, V21, P445, DOI 10.1016/j.pedn.2006.07.002
   Özcan CK, 2002, BURNS, V28, P791, DOI 10.1016/S0305-4179(02)00191-2
   Ozerdem OR, 2003, J CRANIOFAC SURG, V14, P517, DOI 10.1097/00001665-200307000-00023
   Paradiso FV, 2016, ITAL J PEDIATR, V42, DOI 10.1186/s13052-016-0210-6
   Park SH, 2015, ANN DERMATOL, V27, P551, DOI 10.5021/ad.2015.27.5.551
   Persano G, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001953
   Piccin A, 2017, BLOOD TRANSFUS-ITALY, V15, P333, DOI 10.2450/2016.0038-16
   Price-Douglas Webra, 2007, Adv Neonatal Care, V7, P289
   Püttgen K, 2016, PEDIATRICS, V138, DOI 10.1542/peds.2016-0355
   Ramundo J, 2008, J WOUND OSTOMY CONT, V35, P273, DOI 10.1097/01.WON.0000319125.21854.78
   Rentea RM, 2013, J SURG RES, V184, P658, DOI 10.1016/j.jss.2013.05.056
   Riley Kathleen N, 2005, J Burns Wounds, V4, pe8
   Saab IR, 2014, J WOUND CARE, V23, pS5, DOI 10.12968/jowc.2014.23.Sup10.S5
   Saba SC, 2009, J BURN CARE RES, V30, P380, DOI 10.1097/BCR.0b013e3181a2898f
   Santosa KB, 2019, J SURG RES, V235, P560, DOI 10.1016/j.jss.2018.10.043
   Schindler CA, 2011, AM J CRIT CARE, V20, P26, DOI 10.4037/ajcc2011754
   Schlüer AB, 2013, ADV SKIN WOUND CARE, V26, P504, DOI 10.1097/01.ASW.0000433103.55891.af
   Schlüer AB, 2012, OSTOMY WOUND MANAG, V58, P18
   Schoch JJ, 2017, PEDIATR DERMATOL, V34, P39, DOI 10.1111/pde.12990
   Segal I, 2014, J PEDIATR SURG, V49, P381, DOI 10.1016/j.jpedsurg.2013.08.001
   Silverstein P, 2011, J BURN CARE RES, V32, P617, DOI 10.1097/BCR.0b013e318236fe31
   Singer HM, 2018, PEDIATR DERMATOL, V35, P92, DOI 10.1111/pde.13331
   Singer Michael, 2015, Eplasty, V15, pe8
   Sivrioglu N, 2014, ACTA ORTHOP TRAUMATO, V48, P6, DOI 10.3944/AOTT.2014.2941
   Spies M, 2001, PEDIATRICS, V108, P1162, DOI 10.1542/peds.108.5.1162
   Stansby G, 2014, BMJ-BRIT MED J, V348, DOI 10.1136/bmj.g2592
   SZABO S, 1989, AM J MED, V86, P23, DOI 10.1016/0002-9343(89)90153-8
   Than MP, 2013, J DERMATOL TREAT, V24, P290, DOI 10.3109/09546634.2011.654108
   Tiras U, 2005, PEDIATR DERMATOL, V22, P472, DOI 10.1111/j.1525-1470.2005.00119.x
   Totty JP, 2017, J WOUND CARE, V26, P107, DOI 10.12968/jowc.2017.26.3.107
   Upton D, 2015, INT WOUND J, V12, P100, DOI 10.1111/iwj.12059
   Violas P, 2005, J PEDIATR ORTHOP B, V14, P381, DOI 10.1097/01202412-200509000-00013
   Visscher M, 2001, ARCH DERMATOL RES, V293, P491, DOI 10.1007/PL00007463
   Weibel L, 2016, PEDIATR DERMATOL, V33, P184, DOI 10.1111/pde.12767
   Weissenstein Anne, 2014, Br J Nurs, V23, pS32
   Whitaker IS, 2008, ANN PLAS SURG, V60, P333, DOI 10.1097/SAP.0b013e31806bf446
   WHITE JW, 1963, BIOCHIM BIOPHYS ACTA, V73, P57
   Williamson Deborah A, 2017, Clin Microbiol Rev, V30, P827, DOI [10.1128/cmr.00112-16, 10.1128/CMR.00112-16]
   Willock Jane, 2005, Nurs Times, V101, P40
   WINTER GD, 1962, NATURE, V193, P293, DOI 10.1038/193293a0
   Wolcott R, 2015, J WOUND CARE, V24, P366, DOI 10.12968/jowc.2015.24.8.366
   Yang Lujun, 2017, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V31, P1495, DOI 10.7507/1002-1892.201707052
   Yang LJ, 2009, J DERMATOL SCI, V56, P188, DOI 10.1016/j.jdermsci.2009.09.009
   Yasar S, 2018, J WOUND CARE, V27, P768, DOI 10.12968/jowc.2018.27.11.768
NR 154
TC 12
Z9 18
U1 0
U2 14
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD JUN
PY 2020
VL 29
IS 6
BP 321
EP 334
PG 14
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA LV6QY
UT WOS:000538560700004
PM 32530778
DA 2026-07-24
ER

PT J
AU Zhang, YL
   Tian, SW
   Liu, MY
   Zhai, WF
   Zhou, YJ
   Peng, AQ
AF Zhang, Yanlong
   Tian, Shuwei
   Liu, Meiyu
   Zhai, Wenfang
   Zhou, Yujie
   Peng, Aqin
TI Comparison of antibiotic-impregnated bone cement coverage versus vacuum
   sealing drainage in semi-open bone grafting using for tibial fracture
   with infected bone and soft tissue defect: a retrospective analysis
SO BMC MUSCULOSKELETAL DISORDERS
LA English
DT Article
DE Tibial fracture; Infected bone defect; Soft tissue defect; Semiopen bone
   grafting; Bone cement
ID INDUCED MEMBRANE; TRANSPORT
AB Objective To compare antibiotic-impregnated bone cement coverage (bone cement surface technique; BCS-T) versus vacuum sealing drainage (VSD) for tibial fracture with infected bone and soft tissue defect.
   Method This retrospective analysis compared the clinical outcomes in patients undergoing BCS-T (n = 16) versus VSD (n = 15) for tibial fracture with infected bone and soft tissue defect at the Third Hospital of Hebei Medical University from March 2014 to August 2019. For BCS-T group, osseous cavity was filled with autograft bone graft after debridement, and then the wound was covered with a 3-mm layer of bone cement impregnated with vancomycin and gentamycin. The dressing was changed every day in the first week, and every 2 similar to 3 days in the second week. For VSD group, a negative pressure of -150 similar to -350 mmHg was maintained, and the dressing was changed every 5-7 days. All patients received antibiotics treatment based on bacterial culture results for 2 weeks.
   Results The 2 groups did not differ in age, sex and key baseline characteristics, including type of Gustilo-Anderson classification, size of the bone and soft tissue defect, the percentage of primary debridement, bone transport, and the time from injury to bone grafting. The median follow-up was 18.9 months (range:12-40). The time to complete coverage of bone graft by granulation tissue was 21.2 (15.0-44.0) and 20.3 (15.0-24.0) days in the BCS-T and VSD groups, respectively (p = 0.412). The 2 groups also did not differ in wound healing time (3.3 (1.5-5.5) versus 3.2(1.5-6.5) months; p = 0.229) and bone defect healing time (5.4(3.0-9.6) versus 5.9(3.2-11.5) months; p = 0.402). However, the cost of covering material was significantly reduced in the BCS-T group (2071 +/- 134 versus 5542 +/- 905 yuan; p = 0.026). Paley functional classification at 12 months did not differ between the 2 groups (excellent in 87.5% versus 93.3% in the 2 groups; p = 0.306).
   Conclusion BCS-T could achieve clinical outcomes similar to VSD in patients receiving bone graft for tibial fracture with infected bone and soft tissue defect, but material cost was significantly reduced. Randomized controlled trials are needed to verify our finding.
C1 [Zhang, Yanlong; Zhou, Yujie] Hebei Med Univ, Trauma Ctr, Hosp 1, Shijiazhuang 050031, Hebei, Peoples R China.
   [Tian, Shuwei] Hebei Prov Gen Hosp, Shijiazhuang 050057, Hebei, Peoples R China.
   [Liu, Meiyu] Hebei Med Univ, Hosp 2, Shijiazhuang 050051, Hebei, Peoples R China.
   [Zhai, Wenfang; Peng, Aqin] Hebei Med Univ, Dept Orthopaed, Hosp 3, Shijiazhuang 050051, Hebei, Peoples R China.
C3 Hebei Medical University; Hebei Medical University; Hebei Medical
   University
RP Peng, AQ (通讯作者)，Hebei Med Univ, Dept Orthopaed, Hosp 3, Shijiazhuang 050051, Hebei, Peoples R China.
EM pengaqin@126.com
RI /AAM-8825-2020
FU Science and Technology Plan Program of Hebei Province [14277745D,
   14277745D, 14277745D] Funding Source: Medline; Key Research and
   Development Program of Hebei Province [No. 20377744D, No. 20377744D, No.
   20377744D] Funding Source: Medline
CR Archdeacon MT, 2006, J ORTHOP TRAUMA, V20, P134, DOI 10.1097/01.bot.0000184147.82824.7c
   Bankhead-Kendall B, 2019, EUR J TRAUMA EMERG S, V45, P125, DOI 10.1007/s00068-017-0847-x
   Bao TZ, 2017, INT ORTHOP, V41, P2389, DOI 10.1007/s00264-017-3620-1
   Bumbasirevic M, 2010, ARCH ORTHOP TRAUM SU, V130, P739, DOI 10.1007/s00402-009-1014-6
   Carver DC, 2017, ORTHOP CLIN N AM, V48, P137, DOI [10.1016/j.oc1.2016.12.005, 10.1016/j.ocl.2016.12.005]
   Deng ZM, 2014, ARCH MED SCI, V10, P764, DOI 10.5114/aoms.2013.34411
   Duyos OA, 2017, J AM ACAD ORTHOP SUR, V25, P230, DOI 10.5435/JAAOS-D-16-00127
   Giannoudis PV, 2016, INJURY, V47, pS53, DOI 10.1016/S0020-1383(16)30840-3
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Hatzokos I, 2011, J BONE JOINT SURG AM, V93A, P671, DOI 10.2106/JBJS.J.00514
   Karargyris Orestis, 2014, Eur J Orthop Surg Traumatol, V24, P1013, DOI 10.1007/s00590-013-1279-x
   Konda SR, 2017, J ORTHOP TRAUMA, V31, pS21, DOI 10.1097/BOT.0000000000000899
   Ktistakis I, 2014, INJURY, V45, P1025, DOI 10.1016/j.injury.2014.03.022
   Lei H, 1998, J Orthop Sci, V3, P318
   Masquelet AC, 2010, ORTHOP CLIN N AM, V41, P27, DOI 10.1016/j.ocl.2009.07.011
   Paley D, 2000, J ORTHOP TRAUMA, V14, P76, DOI 10.1097/00005131-200002000-00002
   PAPINEAU LJ, 1973, NOUV PRESSE MED, V2, P2753
   Sala F, 2011, J ORTHOP TRAUMA, V25, P162, DOI 10.1097/BOT.0b013e3181e5e160
   Sanders J, 2013, ORTHOPEDICS, V36, P368, DOI 10.3928/01477447-20130426-07
   Singh J, 2012, STRATEG TRAUMA LIMB, V7, P33, DOI 10.1007/s11751-012-0130-y
   UENG WN, 1994, CLIN ORTHOP RELAT R, P175
   Wasko MK, 2015, BIOMED RES INT, V2015, DOI 10.1155/2015/387186
   Weber CD, 2019, EUR J TRAUMA EMERG S, V45, P445, DOI 10.1007/s00068-018-0916-9
NR 23
TC 3
Z9 6
U1 0
U2 5
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2474
J9 BMC MUSCULOSKEL DIS
JI BMC Musculoskelet. Disord.
PD MAY 19
PY 2023
VL 24
IS 1
AR 401
DI 10.1186/s12891-023-06475-x
PG 7
WC Orthopedics; Rheumatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Rheumatology
GA G6BG3
UT WOS:000989981900002
PM 37208629
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Li, SH
   Huang, ZX
   Chen, WL
   Pan, CB
   Huang, ZQ
AF Li, Shihao
   Huang, Zixian
   Chen, Weiliang
   Pan, Chaobin
   Huang, Zhiquan
TI Risk factors for postoperative hemorrhage in patients with oral squamous
   cell carcinoma: A retrospective study
SO HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND
   NECK
LA English
DT Article
DE oral squamous cell carcinoma; radical surgery; postoperative hemorrhage;
   retrospective study; risk factor
ID FREE-FLAP RECONSTRUCTION; VACUUM SEALING DRAINAGE; INTERNAL
   JUGULAR-VEIN; CAROTID BLOWOUT; NECK DISSECTION; HEAD; COMPLICATIONS;
   CANCER; SURGERY; CONTAMINATION
AB AbstarctBackground Postoperative hemorrhage is one of the life-threatening complications of oral cancer surgery. The purpose of this study was to identify the risk factors in a large cohort. Patients and methods Patients with oral squamous cell carcinoma who had received surgery were enrolled. The variables between patients with and without postoperative hemorrhage were compared using univariate and multivariate models. Results Of the 1513 patients (or 1581 cases) enrolled in the study, 34 patients suffered from postoperative hemorrhage. In the univariate analysis, cigarette, and alcohol consumption, floor of mouth tumors, T4 classified tumors, flap reconstruction, surgical site infection, and flap necrosis were risk factors for postoperative hemorrhage. In the multivariate model, flap necrosis and surgical site infection were independent risk factors for postoperative hemorrhage. Conclusions The patients with surgical site infection or flap necrosis should be closely monitored in order to avoid postoperative hemorrhage.
C1 [Li, Shihao; Huang, Zixian; Chen, Weiliang; Pan, Chaobin; Huang, Zhiquan] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Oral & Maxillofacial Surg, 107th Yanjiang Xi Rd, Guangzhou 510120, Guangdong, Peoples R China.
C3 Sun Yat Sen University
RP Huang, ZQ (通讯作者)，Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Oral & Maxillofacial Surg, 107th Yanjiang Xi Rd, Guangzhou 510120, Guangdong, Peoples R China.
EM zhiquanhuang1978@126.com
OI Huang, Zhiquan/0000-0003-0527-9795
CR [Anonymous], HEAD NECK
   [Anonymous], CHIN J MINIM INVASIV
   Awad MI, 2015, JAMA OTOLARYNGOL, V141, P960, DOI 10.1001/jamaoto.2015.2200
   Batstone MD, 2009, EUR ARCH OTO-RHINO-L, V266, P121, DOI 10.1007/s00405-008-0723-8
   Benatar MJ, 2013, J PLAST RECONSTR AES, V66, P478, DOI 10.1016/j.bjps.2012.12.019
   Bhattacharyya N, 2001, ARCH OTOLARYNGOL, V127, P127, DOI 10.1001/archotol.127.2.127
   Bray F, 2018, CA-CANCER J CLIN, V68, P394, DOI [10.3322/caac.21492, 10.3322/caac.21609]
   Chen YJ, 2015, HEAD NECK-J SCI SPEC, V37, P265, DOI 10.1002/hed.23590
   Cleland-Zamudio SS, 2003, HEAD NECK-J SCI SPEC, V25, P357, DOI 10.1002/hed.10219
   Dua A, 2014, VASCULAR, V22, P81, DOI 10.1177/1708538113476024
   Ferri E, 2013, INT J SURG ONCOL, V2013, DOI 10.1155/2013/369345
   Genden EM, 2003, ACTA OTO-LARYNGOL, V123, P795, DOI 10.1080/000116480310001871
   Hamoir M, 2014, CURR TREAT OPTION ON, V15, P611, DOI 10.1007/s11864-014-0311-7
   Head C, 2003, OTOLARYNG HEAD NECK, V129, P48, DOI 10.1016/S0194-5998(03)00480-7
   Hicks WL, 1997, HEAD NECK-J SCI SPEC, V19, P400
   Jain U, 2015, OTOLARYNG HEAD NECK, V153, P71, DOI 10.1177/0194599815581808
   Kamizono K, 2014, ANN SURG ONCOL, V21, P1700, DOI 10.1245/s10434-014-3498-8
   Kuo SC, 2015, J DIABETES COMPLICAT, V29, P1071, DOI 10.1016/j.jdiacomp.2015.06.010
   Li RG, 2012, INJURY, V43, P822, DOI 10.1016/j.injury.2011.09.031
   Lin YS, 2015, ULUS TRAVMA ACIL CER, V21, P68, DOI 10.5505/tjtes.2015.76992
   Liu L, 2017, ALCOHOL CLIN EXP RES, V41, P291, DOI 10.1111/acer.13295
   Loupatatzi A, 2014, J ORAL MAXIL SURG, V72, P178, DOI 10.1016/j.joms.2013.05.013
   MARAN AGD, 1989, J LARYNGOL OTOL, V103, P760, DOI 10.1017/S002221510011000X
   MARKS SC, 1990, HEAD NECK-J SCI SPEC, V12, P342, DOI 10.1002/hed.2880120412
   Mazurek MJ, 2014, HEAD NECK-J SCI SPEC, V36, P1408, DOI 10.1002/hed.23473
   Mcdonald MW, 2012, INT J RADIAT ONCOL, V82, P1083, DOI 10.1016/j.ijrobp.2010.08.029
   Mekel M, 2010, AM J SURG, V199, P485, DOI 10.1016/j.amjsurg.2009.04.006
   Omura K, 2014, INT J CLIN ONCOL, V19, P423, DOI 10.1007/s10147-014-0689-z
   Opielka Witold, 2014, Przegl Lek, V71, P690
   Patel RS, 2010, HEAD NECK-J SCI SPEC, V32, P1345, DOI 10.1002/hed.21331
   Peters TTA, 2014, ANN SURG ONCOL, V21, P963, DOI 10.1245/s10434-013-3375-x
   Pieters M, 2015, BLOOD REV, V29, P231, DOI 10.1016/j.blre.2014.12.005
   Pluvy I, 2015, ANN CHIR PLAST ESTH, V60, pE15, DOI 10.1016/j.anplas.2014.09.011
   Powitzky R, 2010, ANN OTO RHINOL LARYN, V119, P476, DOI 10.1177/000348941011900709
   SARKAR S, 1990, J SURG ONCOL, V43, P245, DOI 10.1002/jso.2930430411
   Smith RB, 2007, HEAD NECK-J SCI SPEC, V29, P446, DOI 10.1002/hed.20540
   Wang J, 2015, MINERVA CHIR, V70, P17
   Wu Y, 2018, INT J ORAL MAX SURG, V47, P824, DOI 10.1016/j.ijom.2018.01.018
   Yang ZhiHua Yang ZhiHua, 2012, Journal of Tropical Medicine (Guangzhou), V12, P40
NR 39
TC 3
Z9 5
U1 0
U2 8
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1043-3074
EI 1097-0347
J9 HEAD NECK-J SCI SPEC
JI Head Neck-J. Sci. Spec. Head Neck
PD JUL
PY 2019
VL 41
IS 7
BP 2093
EP 2099
DI 10.1002/hed.25659
PG 7
WC Otorhinolaryngology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology; Surgery
GA ID6UV
UT WOS:000471816100009
PM 30706556
DA 2026-07-24
ER

PT J
AU Wen, JX
   Li, ZJ
   Chi, YR
   Chen, B
   Hong, T
   Liu, ZF
   Yu, NZ
   Wang, XJ
AF Wen, Junxian
   Li, Zhijin
   Chi, Yarong
   Chen, Bo
   Hong, Tao
   Liu, Zhifei
   Yu, Nanze
   Wang, Xiaojun
TI Vulvar migration of injected polyacrylamide hydrogel following breast
   augmentation: a case report and literature review
SO BMC WOMENS HEALTH
LA English
DT Article
DE Breast augmentation; Vulva; Polyacrylamide hydrogel; Migration; Case
   Report; Literature Review
ID COMPLICATIONS; MANAGEMENT; FEATURES; PATIENT; FILLER
AB BackgroundVulvar migration is a rare complication of filler injection for breast augmentation, generally presenting as repeated pain and fever. We will report a case of woman with polyacrylamide hydrogel breast injection develops vulvar abscess.Case presentationA woman with a history of polyacrylamide hydrogel breast injection was noted to have vulvar abscess due to migration of filler materials. Filler removal surgery and vacuum sealing drainage was performed for this patient. The patient was discharged from the hospital with no further complications. After a review of pertinent literature, only four previous case reports are found. Local inflammatory response, infection, large volume injections, inframammary fold destruction, hematogenous or lymphatic migrate, trauma, gravity and external pressure could play essential parts in the migration of injected filler.ConclusionPolyacrylamide hydrogel migration poses a worldwide challenge, necessitating personalized solutions. Our case study underscores the importance of comprehensive examinations for individuals with a history of filler breast injection when suspecting vulvar filler migration.
C1 [Wen, Junxian; Li, Zhijin; Liu, Zhifei; Yu, Nanze; Wang, Xiaojun] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Plast Surg, Beijing, Peoples R China.
   [Chi, Yarong] PUMC & Chinese Acad Med Sci, Peking Union Med Coll PUMC, Beijing, Peoples R China.
   [Chen, Bo] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Pathol, Beijing, Peoples R China.
   [Hong, Tao] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Gen Surg, Beijing, Peoples R China.
   [Hong, Tao; Yu, Nanze] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Int Med Serv, Beijing, Peoples R China.
C3 Chinese Academy of Medical Sciences - Peking Union Medical College;
   Peking Union Medical College Hospital; Peking Union Medical College;
   Chinese Academy of Medical Sciences - Peking Union Medical College;
   Peking Union Medical College; Chinese Academy of Medical Sciences -
   Peking Union Medical College; Peking Union Medical College; Peking Union
   Medical College Hospital; Chinese Academy of Medical Sciences - Peking
   Union Medical College; Peking Union Medical College Hospital; Peking
   Union Medical College; Chinese Academy of Medical Sciences - Peking
   Union Medical College; Peking Union Medical College Hospital; Peking
   Union Medical College
RP Yu, NZ; Wang, XJ (通讯作者)，Chinese Acad Med Sci, Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Plast Surg, Beijing, Peoples R China.; Yu, NZ (通讯作者)，Chinese Acad Med Sci, Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Int Med Serv, Beijing, Peoples R China.
EM yunanze@pumch.cn; pumchwxj@163.com
RI ; tao, hong/HGA-0940-2022; wang, xiaojun/NFT-0476-2025
OI Wen, Junxian/0009-0004-5549-122X; 
FU National High Level Hospital Clinical Research Funding
FX No Statement Available
CR Adams WP, 2012, PLAST RECONSTR SURG, V130, p598E, DOI 10.1097/PRS.0b013e318262f607
   Alijotas-Reig J, 2013, CLIN REV ALLERG IMMU, V45, P97, DOI 10.1007/s12016-012-8348-5
   Ben Khedher N, 2011, EUR J RADIOL, V78, P104, DOI 10.1016/j.ejrad.2009.09.021
   Buzzaccarini G, 2022, J PLAST RECONSTR AES, V75, P2850, DOI 10.1016/j.bjps.2022.06.047
   Chen BG, 2016, AESTHET PLAST SURG, V40, P482, DOI 10.1007/s00266-016-0646-5
   Chen L, 2015, INT J CLIN EXP MED, V8, P3360
   Choi YJ, 2022, SKELETAL RADIOL, V51, P2223, DOI 10.1007/s00256-022-04037-1
   Coombs DM, 2019, CLEV CLIN J MED, V86, P111, DOI 10.3949/ccjm.86a.18017
   Dean RA, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001849
   Ding FX, 2022, AESTHET PLAST SURG, V46, P2107, DOI 10.1007/s00266-022-02876-w
   Duncan AM, 2022, PLAST RECONSTR SURG, V149, P28, DOI 10.1097/PRS.0000000000008671
   Hallab NJ, 2019, AESTHET SURG J, V39, pS36, DOI 10.1093/asj/sjy335
   Ishii H, 2014, PLAST SURG-CHIR PLAS, V22, P171, DOI 10.1177/229255031402200305
   Jeng CJ, 2005, BJOG-INT J OBSTET GY, V112, P1659, DOI 10.1111/j.1471-0528.2005.00761.x
   Jin R, 2018, AESTHET PLAST SURG, V42, P402, DOI 10.1007/s00266-017-1006-9
   Jung BK, 2018, AESTHET PLAST SURG, V42, P1252, DOI 10.1007/s00266-018-1107-0
   Kim J, 2019, AESTHET PLAST SURG, V43, P46, DOI 10.1007/s00266-018-1242-7
   Luo SK, 2011, J PLAST RECONSTR AES, V64, P731, DOI 10.1016/j.bjps.2010.10.004
   Maw AM, 2021, CLIN NUCL MED, V46, pE206, DOI 10.1097/RLU.0000000000003403
   Namgoong S, 2020, AESTHET PLAST SURG, V44, P1997, DOI 10.1007/s00266-020-01889-7
   Nomoto S, 2021, PRS-GLOB OPEN, V9, DOI 10.1097/GOX.0000000000003296
   Oh JH, 2016, PRS-GLOB OPEN, V4, DOI 10.1097/GOX.0000000000001011
   Ovrebo O, 2022, BIOENG TRANSL MED, V7, DOI 10.1002/btm2.10295
   Rish A, 2014, J COSMET DERMATOL-US, V13, P253, DOI 10.1111/jocd.12112
   Son MJ, 2018, J ULTRAS MED, V37, P1835, DOI 10.1002/jum.14527
   U.S. Food and Drug Administration, Dermal Fillers (Soft Tissue Fillers)
   Unukovych D, 2012, WORLD J SURG, V36, P695, DOI 10.1007/s00268-011-1273-6
   Wang B, 2021, BMC SURG, V21, DOI 10.1186/s12893-021-01097-3
   Wozniak-Roszkowska E, 2020, RHEUMATOL INT, V40, P1851, DOI 10.1007/s00296-020-04605-5
   Wu JF, 2014, BREAST CARE, V9, P273, DOI 10.1159/000365954
   Zhang MX, 2019, WORLD J CLIN CASES, V7, P3322, DOI 10.12998/wjcc.v7.i20.3322
NR 33
TC 4
Z9 4
U1 0
U2 6
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1472-6874
J9 BMC WOMENS HEALTH
JI BMC Womens Health
PD MAR 2
PY 2024
VL 24
IS 1
AR 152
DI 10.1186/s12905-024-02998-0
PG 9
WC Public, Environmental & Occupational Health; Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Public, Environmental & Occupational Health; Obstetrics & Gynecology
GA KI8N6
UT WOS:001179423300001
PM 38431590
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Chen, M
   Ling, Y
   Yang, BB
AF Chen, Ming
   Ling, Yi
   Yang, Beibei
TI Management of late cervical esophageal perforation
SO ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA &
   EMERGENCY SURGERY
LA English
DT Article
DE Esophageal perforation; late cervical management; primary repair
ID MEDIASTINITIS; INFECTION
AB BACKGROUND
   We aimed to identify different methods of treating late perforation of the cervical esophagus.
   METHODS
   Ten late cervical esophageal perforations were caused by foreign bodies. The subjects were divided into three groups according to their diagnosis and treatment as follows: Group I: Cases with cervical abscess were drained by lateral cervical incision and primarily repaired, Group II: Cases with cervical abscess were drained by lateral cervical incision, and any foreign body granulomas found were removed, and Group III: Foreign bodies were removed. All cases were given broad-spectrum antibiotics and were prohibited from any oral food, except Case 5.
   RESULTS
   All patients recovered without mortality and retained normal swallow function. The time for treatment in each group was different.
   CONCLUSION
   The conservative management of removal of foreign body, prohibition of oral food and administration of broad-spectrum antibiotics is supported. Perforations with the presence of abscess can be surgically treated by debridement closure combined with strip muscle flap repair and irrigation drainage. Granuloma can be removed by lateral cervical incision and vacuum sealing drainage.
C1 [Chen, Ming; Ling, Yi; Yang, Beibei] Zhejiang Univ, Affiliated Hosp 2, Sch Med, Dept Otolaryngol, Hangzhou, Zhejiang, Peoples R China.
C3 Zhejiang University
RP Yang, BB (通讯作者)，Jiefang Rd 88, Hangzhou 310009, Zhejiang, Peoples R China.
EM yangbb1959@sina.com
RI Chen, Mingyu/R-6690-2019
CR Baum ED, 2008, ENT-EAR NOSE THROAT, V87, P44, DOI 10.1177/014556130808700115
   Breigeiron R, 2008, DIS ESOPHAGUS, V21, P266, DOI 10.1111/j.1442-2050.2007.00779.x
   Brinster CJ, 2004, ANN THORAC SURG, V77, P1475, DOI 10.1016/j.athoracsur.2003.08.037
   Demirbag S, 2005, CLIN PEDIATR, V44, P131, DOI 10.1177/000992280504400204
   Eroglu A, 2009, DIS ESOPHAGUS, V22, P374, DOI 10.1111/j.1442-2050.2008.00918.x
   Gupta NM, 2004, AM J SURG, V187, P58, DOI 10.1016/j.amjsurg.2002.11.004
   Kay Marsha, 2005, Curr Gastroenterol Rep, V7, P212, DOI 10.1007/s11894-005-0037-6
   LAM HC, 2003, ENT-EAR NOSE THROAT, V82, P789
   Lam Henry Chuen Kwong, 2003, Ear Nose Throat J, V82, P789
   Miller MC, 2007, LARYNGOSCOPE, V117, P2013, DOI 10.1097/MLG.0b013e31813437a0
   Ökten I, 2001, SURG TODAY, V31, P36
   Righini CA, 2008, WORLD J GASTROENTERO, V14, P1450, DOI 10.3748/wjg.14.1450
   Sng KK, 2008, ANZ J SURG, V78, P573, DOI 10.1111/j.1445-2197.2008.04575.x
   Vogel SB, 2005, ANN SURG, V241, P1016, DOI 10.1097/01.sla.0000164183.91898.74
   Wang LT, 2007, SOUTH MED J, V100, P727, DOI 10.1097/SMJ.0b013e318063ed9f
   Wu JC, 2007, ACTA CRYSTALLOGR E, V63, pO2844, DOI 10.1107/S160053680702096X
   Zumbro GL, 2002, AM SURGEON, V68, P36
NR 17
TC 4
Z9 6
U1 0
U2 2
PU TURKISH ASSOC TRAUMA EMERGENCY SURGERY
PI ISTANBUL
PA KOPRULU MEHMET PASA SOC, DENIZ ABDAL MAH, DADASOGLU AP, 25-1 SEHREMINI,
   ISTANBUL, 00000, TURKEY
SN 1306-696X
J9 ULUS TRAVMA ACIL CER
JI Ulus. Travma Acil Cerrahi Derg.
PD NOV 1
PY 2010
VL 16
IS 6
BP 511
EP 515
PG 5
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA 678PM
UT WOS:000284091700006
PM 21153943
DA 2026-07-24
ER

PT J
AU Li, J
   Shi, JB
   Hong, P
   Wang, YS
   Ze, HR
   Lee, RJ
   Tang, X
AF Li, Jin
   Shi, Jie Bao
   Hong, Pan
   Wang, Yu Shang
   Ze, Hao Ren
   Lee, Rushyuan Jay
   Tang, Xin
TI Combined treatment with vacuum sealing drainage, TopClosure device, and
   Ilizarov technique for traumatic hemipelvectomy A rare case report of
   successful repairing of large-size soft tissue defects
SO MEDICINE
LA English
DT Article
DE Ilizarov technique; large-size soft tissue defects; RNPT; TopClosure
   device; traumatic hemipelvectomy
ID ASSISTED CLOSURE VAC(TM); INJURIES
AB Rationale: Traumatic hemipelvectomy is a rare but lethal catastrophic injury.
   Patient concerns: A case of a very young child with open fracture of left sacroiliac joint dislocation and pubic symphysis diastasis, suffered from a severe large-size soft tissue defects.
   Diagnosis: Traumatic hemipelvectomy.
   Interventions: Complete amputation was performed and three kinds of surgical techniques including regulated negative pressure-assisted wound therapy (RNPT), TopClosure device, and Ilizarov technique were jointly utilized to secure closure in the further revisions of the soft tissue injury and reconstruct reconstructive surgery.
   Outcomes: Six months after hospital discharge, the patient was able to ambulate with a single limb and a prosthesis and she is independent in many activities of daily living currently.
   Lessons: We report this case to share experience with other clinicians in the management of this deadly extensive defects after traumatic hemipelvectomy in patients.
C1 [Li, Jin; Shi, Jie Bao; Hong, Pan; Wang, Yu Shang; Ze, Hao Ren; Tang, Xin] Huazhong Univ Sci & Technol, Tongji Med Coll, Union Hosp, Dept Orthopaed Surg, Wuhan 430022, Hubei, Peoples R China.
   [Lee, Rushyuan Jay] Johns Hopkins Univ Hosp, Bloomberg Childrens Hosp, Dept Orthopaed Surg, Baltimore, MD 21287 USA.
C3 Huazhong University of Science & Technology; Johns Hopkins University;
   Johns Hopkins Medicine
RP Tang, X (通讯作者)，Wuhan Union Hosp, Wuhan 430022, Hubei, Peoples R China.
EM dr_xintang@hust.edu.cn
OI Tang, Xin/0000-0002-6860-6530
FU National Natural Science Foundation of China [81470100]
FX National Natural Science Foundation of China (81470100).
CR BAKER SP, 1974, J TRAUMA, V14, P187, DOI 10.1097/00005373-197403000-00001
   Cavadas PC, 2008, J TRAUMA, V65, P1551, DOI 10.1097/01.ta.0000197424.47342.8a
   D'Alleyrand Jean-Claude G, 2012, J Surg Orthop Adv, V21, P38
   Hak DJ, 1997, J TRAUMA, V42, P1046, DOI 10.1097/00005373-199706000-00010
   Hao S, 2016, EUR J TRAUMA EMERG S, V42, P87, DOI 10.1007/s00068-015-0509-9
   Hu N, 2015, J HUAZHONG U SCI-MED, V35, P563, DOI 10.1007/s11596-015-1471-9
   Labler L, 2002, Swiss Surg, V8, P266, DOI 10.1024/1023-9332.8.6.266
   Labler L, 2007, LANGENBECK ARCH SURG, V392, P601, DOI 10.1007/s00423-006-0090-0
   Lasurt S, 2010, INJURY, V41, P874, DOI 10.1016/j.injury.2010.04.009
   Lawless MW, 1997, J TRAUMA, V42, P1169, DOI 10.1097/00005373-199706000-00034
   LIPKOWITZ G, 1985, J TRAUMA, V25, P823, DOI 10.1097/00005373-198509000-00002
   Marek DJ, 2005, AM J SURG, V190, P123, DOI 10.1016/j.amjsurg.2005.05.038
   Osti M, 2006, INJURY, V37, P1015, DOI 10.1016/j.injury.2006.06.022
   Ozer MT, 2011, INT WOUND J, V8, P599, DOI 10.1111/j.1742-481X.2011.00835.x
   Penn-Barwell JG, 2012, J BONE JOINT SURG BR, V94B, P107, DOI 10.1302/0301-620X.94B1.27026
   Rieger H, 1998, J TRAUMA, V45, P422, DOI 10.1097/00005373-199808000-00045
   Schoderbek RJ, 2005, ARCH ORTHOP TRAUM SU, V125, P358, DOI 10.1007/s00402-005-0814-6
   Topaz M, 2012, EUR J PLAST SURG, V35, P533, DOI 10.1007/s00238-011-0671-1
   Walcher F, 2013, INJURY, V44, P1252, DOI 10.1016/j.injury.2012.09.025
NR 19
TC 6
Z9 8
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD JAN
PY 2019
VL 98
IS 4
AR e14205
DI 10.1097/MD.0000000000014205
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA HQ3FY
UT WOS:000462296900045
PM 30681595
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Zhang, H
   Chen, GP
   Yu, YR
   Guo, JH
   Tan, Q
   Zhao, YN
AF Zhang, Han
   Chen, Guopu
   Yu, Yunru
   Guo, Jiahui
   Tan, Qian
   Zhao, Yuanjin
TI Microfluidic Printing of Slippery Textiles for Medical Drainage around
   Wounds
SO ADVANCED SCIENCE
LA English
DT Article
DE 3D printing; microfibers; microfluidics; wettability; wound healing
ID SURFACES; TRANSPARENT; ARRAYS
AB Surface materials with specific wettability play significant roles in existing fields from environmental protection to biomedicine. Here, a 3D droplet transport microfiber textile with slippery liquid-infused porous surface is presented for medical drainage around wounds. The textile is fabricated by using a simple capillary microfluidic printing method to continuously spin polyurethane microfibers with liquid paraffin-infused porous surface and print them into a 3D-structure. Benefiting from the specific surface porous structure and oil encapsulation of the microfibers, aqueous droplets could be nondestructively and rapidly transported not only in simple single, double or multiple microfiber systems, but also in the microfibers composed stereoscopic textile through the microfluidic 3D printing. Based on this feature, it is demonstrated that the 3D slippery microfiber textile coupled with a vacuum sealing drainage therapy could significantly enhance the wound exudation drainage efficiency, reduce tissue injury, and prolong the effective service life in versatile wounds management. Thus, it is believed that the slippery microfiber textiles have potential for clinical applications.
C1 [Zhang, Han; Chen, Guopu; Tan, Qian; Zhao, Yuanjin] Nanjing Univ, Sch Med, Affiliated Hosp, Dept Burns & Plast Surg,Nanjing Drum Tower Hosp, Nanjing 210008, Peoples R China.
   [Zhang, Han; Zhao, Yuanjin] Xuzhou Med Univ, Clin Coll, Nanjing Drum Tower Hosp, Dept Clin Lab, Nanjing 210008, Peoples R China.
   [Zhang, Han; Yu, Yunru; Guo, Jiahui; Zhao, Yuanjin] Southeast Univ, State Key Lab Bioelect, Sch Biol Sci & Med Engn, Nanjing 210096, Peoples R China.
C3 Nanjing University; Xuzhou Medical University; Nanjing University;
   Southeast University - China
RP Zhao, YN (通讯作者)，Nanjing Univ, Sch Med, Affiliated Hosp, Dept Burns & Plast Surg,Nanjing Drum Tower Hosp, Nanjing 210008, Peoples R China.; Zhao, YN (通讯作者)，Xuzhou Med Univ, Clin Coll, Nanjing Drum Tower Hosp, Dept Clin Lab, Nanjing 210008, Peoples R China.; Zhao, YN (通讯作者)，Southeast Univ, State Key Lab Bioelect, Sch Biol Sci & Med Engn, Nanjing 210096, Peoples R China.
EM yjzhao@seu.edu.cn
RI Zhao, Yuanjin/I-1861-2013; Zhang, Han/HSG-5211-2023
OI Zhao, Yuanjin/0000-0001-9242-4000; Yu, Yunru/0000-0003-3182-5753; 
FU National Natural Science Foundation of China [61927805, 51522302];
   Natural Science Foundation of Jiangsu [BE2018707]; Scientific Research
   Foundation of Nanjing University; Nanjing Drum Tower Hospital
FX H.Z. and G.P.C. contributed equally to this work. This work was
   supported by the National Natural Science Foundation of China (Grants
   61927805 and 51522302), the Natural Science Foundation of Jiangsu (Grant
   No. BE2018707), and the Scientific Research Foundation of Nanjing
   University and Nanjing Drum Tower Hospital. All rats were treated
   strictly according to the Laboratory Animal Care and Use Guidelines. All
   of the animal care and experimental procedures were reviewed and
   approved by the Animal Investigation Ethics Committee of Nanjing General
   Hospital of Nanjing Command.
CR Alakus H., 2018, SURG ENDOSC, V32, P1906
   Amini S, 2017, SCIENCE, V357, P668, DOI 10.1126/science.aai8977
   Au AK, 2016, ANGEW CHEM INT EDIT, V55, P3862, DOI 10.1002/anie.201504382
   Cao MY, 2016, ACS APPL MATER INTER, V8, P3615, DOI 10.1021/acsami.5b07881
   Chen GP, 2019, RESEARCH-CHINA, V2019, DOI 10.34133/2019/6175398
   Dibyangana P., 2018, J MATER CHEM A, V6
   Howell C, 2018, ADV MATER, V30, DOI 10.1002/adma.201802724
   Kamei J, 2015, ADV FUNCT MATER, V25, P4195, DOI 10.1002/adfm.201501020
   Kim JG, 2014, SMALL, V10, P2487, DOI 10.1002/smll.201303051
   Kim JH, 2014, LANGMUIR, V30, P1473, DOI 10.1021/la403220p
   Kim SH, 2014, NAT COMMUN, V5, DOI 10.1038/ncomms4068
   Kolesky DB, 2014, ADV MATER, V26, P3124, DOI 10.1002/adma.201305506
   Lafuma A, 2003, NAT MATER, V2, P457, DOI 10.1038/nmat924
   Ma QM, 2016, ACS MACRO LETT, V5, P666, DOI 10.1021/acsmacrolett.6b00228
   Miljkovic N, 2013, NANO LETT, V13, P179, DOI 10.1021/nl303835d
   Muth JT, 2014, ADV MATER, V26, P6307, DOI 10.1002/adma.201400334
   Polat A, 2019, LAB CHIP, V19, P550, DOI 10.1039/c8lc01190g
   Qin M, 2018, ADV MATER, V30, DOI 10.1002/adma.201800468
   Rahmawan Y, 2013, J MATER CHEM A, V1, P2955, DOI 10.1039/c2ta00288d
   Shao CM, 2019, RESEARCH-CHINA, V2019, DOI 10.34133/2019/9783793
   Shastri A, 2015, NAT CHEM, V7, P447, DOI [10.1038/NCHEM.2203, 10.1038/nchem.2203]
   Song Y, 2018, NAT COMMUN, V9, DOI 10.1038/s41467-018-04510-3
   Tian XL, 2016, SCIENCE, V352, P142, DOI 10.1126/science.aaf2073
   Wang J, 2015, MINERVA CHIR, V70, P17
   Wang J, 2018, SCI ADV, V4, DOI 10.1126/sciadv.aat7392
   Wang J, 2017, SCI ADV, V3, DOI 10.1126/sciadv.1700004
   Wang JX, 2011, ACCOUNTS CHEM RES, V44, P405, DOI 10.1021/ar1001236
   Wang JH, 2019, ACS APPL MATER INTER, V11, P7591, DOI 10.1021/acsami.8b21088
   Wang Y, 2020, SCI ADV, V6, DOI 10.1126/sciadv.aax8258
   Wong TS, 2011, NATURE, V477, P443, DOI 10.1038/nature10447
   Yang K, 2016, BIOINSPIR BIOMIM, V11, DOI 10.1088/1748-3190/11/6/066002
   Yao X, 2011, ADV MATER, V23, P719, DOI 10.1002/adma.201002689
   Yu YR, 2017, ADV MATER, V29, DOI 10.1002/adma.201605765
   Zhang M, 2014, ACS APPL MATER INTER, V6, P22108, DOI 10.1021/am505490w
   Zhang XX, 2019, P NATL ACAD SCI USA, V116, P20863, DOI 10.1073/pnas.1912467116
   Zhang XX, 2019, SCI BULL, V64, P1110, DOI 10.1016/j.scib.2019.06.016
   Zhang YS, 2017, ANN BIOMED ENG, V45, P148, DOI 10.1007/s10439-016-1612-8
   Zhang YS, 2016, BIOMATERIALS, V110, P45, DOI 10.1016/j.biomaterials.2016.09.003
   Zhao YY, 2017, ADV FUNCT MATER, V27, DOI 10.1002/adfm.201701466
NR 39
TC 110
Z9 121
U1 4
U2 240
PU WILEY-V C H VERLAG GMBH
PI WEINHEIM
PA POSTFACH 101161, 69451 WEINHEIM, GERMANY
EI 2198-3844
J9 ADV SCI
JI Adv. Sci.
PD AUG
PY 2020
VL 7
IS 16
AR 2000789
DI 10.1002/advs.202000789
EA JUN 2020
PG 7
WC Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials
   Science, Multidisciplinary
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Chemistry; Science & Technology - Other Topics; Materials Science
GA NQ7OW
UT WOS:000539600900001
PM 32832352
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Miller, M
   Bybordi, F
AF Miller, Michael
   Bybordi, Farhad
TI Negative Pressure Darwinism: Survival of the Fittest Paradigm
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Editorial Material
ID MICROVASCULAR BLOOD-FLOW; WOUND THERAPY
AB The use of negative pressure for wound healing has been based on a set of parameters and devices that until recently were combined into a single paradigm. Despite historical and more recent evidence providing viable alternative considerations, it is only recently that this paradigm and its tenets have come into question. As the understanding of the limits of the current paradigm and specific instances of its benefits and drawbacks are identified, shifts in the paradigm must take place if the therapy is to evolve, develop, and continue to be efficacious. The pertinence of the concept of survival of the fittest is used to explore the need for a paradigm shift in negative pressure wound therapy.
C1 [Miller, Michael; Bybordi, Farhad] Wound Healing Ctr, Bedford, IN 47421 USA.
RP Miller, M (通讯作者)，Wound Healing Ctr, 2900 16th St, Bedford, IN 47421 USA.
EM doc@docmillers.com
RI Miller, Michael/K-6928-2017
CR *AM PROF WOUND CAR, 2009, US NOV ANT SILV NEG
   *AM PROF WOUND CAR, 2009, ANPT HAND SOL BURNS
   [Anonymous], 2017, What is the difference between one-way traffic and two-way traffic (with examples)?
   BURTON R, 1850, ANATOMY MELANCHOLY 1
   *CORT CORP, MAT SAF DAT SHEET
   Davydov Iu A, 1986, Vestn Khir Im I I Grek, V137, P66
   *KEND AMD ANT GAUZ, MAT SAF DAT
   LARICHEV AB, 2005, STUDIES CLIN PHYSL T
   Malli Suzanne, 2005, Nursing, V35, P25
   Miller Michael S, 2007, Int Wound J, V4, P88, DOI 10.1111/j.1742-481X.2006.00231.x
   Miller MS, 2005, OSTOMY WOUND MANAG, V51, P44
   Miller MS, 2005, WOUNDS, V17, P290
   Miller MS, 2005, PODIATRY MANAGE, V24, P121
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Motta Glenda J, 2004, Ostomy Wound Manage, V50, P48
   Patten WN, 1998, J SOUND VIB, V217, P145, DOI 10.1006/jsvi.1998.1760
   Spencer Herbert., 1851, SOCIAL STAT
   Timmers MS, 2005, ANN PLAS SURG, V55, P665, DOI 10.1097/01.sap.0000187182.90907.3d
   USOPOV YN, 1987, VESTNIK KHIRUGII, V4, P42
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   2004, CLIN S ADV SKIN WOUN
   2006, AM PROF WOUND CAR AS
   2005, NAT PRESS ULC ADV PA
   2006, CLIN S ADV SKIN WOUN
   2006, S ADV WOUND CAR APR
   2005, CLIN S SKIN WOUND CA
NR 26
TC 1
Z9 1
U1 0
U2 2
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUL
PY 2009
VL 21
IS 7
BP 192
EP 197
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 472KD
UT WOS:000268128600006
PM 25903511
DA 2026-07-24
ER

PT J
AU Willy, C
AF Willy, Christian
TI Breakthrough ideas leading to new futures: next steps
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE ABThera (TM) therapy; Incisions; NPWT; Open abdomen; Prevena (TM)
   therapy
AB In 2010, the educational International Surgical Wound Forum (ISWF) was created to facilitate discussion among global experts regarding modern wound treatment challenges and how negative pressure wound therapy (NPWT) could be used to address those challenges. This is the second of two supplements, which are based on 2012 and 2013 ISWF presentations and demonstrate the evolution of NPWT's role in wound care. The previous supplement provided an overview of critical health care issues and current clinical practice and reviewed evidence and experience using NPWT with instillation of topical wound solutions. This supplement presents clinical experience using negative pressure over closed surgical incisions, in the open abdomen, and in wounds with enteroatmospheric fistulas.
C1 [Willy, Christian] Bundeswehrkrankenhaus Berlin, Dept Traumatol & Orthopaed Sept & Plast Surg, D-10115 Berlin, Germany.
RP Willy, C (通讯作者)，Bundeswehrkrankenhaus Berlin, Colonel Dept Traumatol & Orthopaed Sept & Plast S, Scharnhorststr 13, D-10115 Berlin, Germany.
EM christianwilly@bundeswehr.org
NR 0
TC 0
Z9 0
U1 0
U2 5
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JUN
PY 2014
VL 11
SU 1
SI SI
BP 1
EP 2
DI 10.1111/iwj.12236
PG 2
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA AJ3MO
UT WOS:000337570900001
PM 24851727
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Simonson, DC
   Elliott, AD
   Roukis, TS
AF Simonson, Devin C.
   Elliott, Andrew D.
   Roukis, Thomas S.
TI Catastrophic Failure of an Infected Achilles Tendon Rupture Repair
   Managed with Combined Flexor Hallucis Longus and Peroneus Brevis Tendon
   Transfer
SO CLINICS IN PODIATRIC MEDICINE AND SURGERY
LA English
DT Article
DE Complication; Negative pressure wound therapy; Postoperative infection;
   Skin graft; Tendon transfer
ID RECONSTRUCTION
AB Deep infection is one of the most devastating complications following repair of an Achilles tendon rupture. Treatment requires not only culture-driven antibiotic therapy but, more importantly, appropriate debridement of some or even all of the Achilles tendon. This may necessitate delayed reconstruction of the Achilles tendon. The authors present a successful case of reconstruction of a chronically infected Achilles tendon in an otherwise healthy 43-year-old man via a multistaged approach using the flexor hallucis longus and peroneus brevis tendons. We also provide a brief review of the literature regarding local tendon transfer used in the reconstruction of Achilles tendon rupture.
C1 [Simonson, Devin C.; Roukis, Thomas S.] Gundersen Hlth Syst, Dept Orthopaed, La Crosse, WI 54601 USA.
   [Simonson, Devin C.; Roukis, Thomas S.] Gundersen Hlth Syst, Dept Podiatry, La Crosse, WI 54601 USA.
   [Simonson, Devin C.; Roukis, Thomas S.] Gundersen Hlth Syst, Dept Sports Med, La Crosse, WI 54601 USA.
   [Elliott, Andrew D.] Gunderson Med Fdn, Podiatr Med & Surg Resident PGY 3, La Crosse, WI 54601 USA.
RP Roukis, TS (通讯作者)，Gundersen Hlth Syst, Dept Orthopaed, 1900 South Ave, La Crosse, WI 54601 USA.
EM tsroukis@gundersenhealth.org
CR Ahluwalia R, 2013, FOOT ANKLE SURG, V19, pE7, DOI 10.1016/j.fas.2012.11.003
   Akhil AT, 2013, MALAYS ORTHOP J, V7, P19, DOI 10.5704/MOJ.1303.011
   Maffulli N, 1999, J BONE JOINT SURG AM, V81A, P1019, DOI 10.2106/00004623-199907000-00017
   Moroney P J, 2012, Foot Ankle Surg, V18, pe25, DOI 10.1016/j.fas.2012.03.004
   PEREZTEUFFER A, 1974, ORTHOP CLIN N AM, V5, P89
   Pintore E, 2001, J TRAUMA, V50, P71, DOI 10.1097/00005373-200101000-00013
   Rosenzweig S, 2009, FOOT ANKLE CLIN, V14, P699, DOI 10.1016/j.fcl.2009.07.002
   Roukis T S, 2005, J Wound Care, V14, P173
   Schade VL, 2010, J FOOT ANKLE SURG, V49, P55, DOI 10.1053/j.jfas.2009.06.010
   Schade Valerie L, 2008, Foot Ankle Spec, V1, P147, DOI 10.1177/1938640008317357
   TURCO VJ, 1987, FOOT ANKLE, V7, P253, DOI 10.1177/107110078700700407
   Wapner K L, 1993, Foot Ankle, V14, P443
   Wegrzyn J, 2010, INT ORTHOP, V34, P1187, DOI 10.1007/s00264-009-0859-1
   Young JS, 2005, TECH FOOT ANKLE SURG, V4, P143, DOI 10.1097/01.btf.0000177227.37589.d2
NR 14
TC 9
Z9 12
U1 0
U2 4
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0891-8422
EI 1558-2302
J9 CLIN PODIATR MED SUR
JI Clin. Podiatr. Med. Surg.
PD JAN
PY 2016
VL 33
IS 1
BP 153
EP +
DI 10.1016/j.cpm.2015.06.006
PG 11
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA CZ0KL
UT WOS:000366793600016
PM 26590732
DA 2026-07-24
ER

PT J
AU Kisielewski, M
   Richter, K
   Pisarska-Adamczyk, M
   Wysocki, M
   Klos, N
   Stefura, T
   Wojewoda, T
   Wysocki, WM
AF Kisielewski, Michal
   Richter, Karolina
   Pisarska-Adamczyk, Magdalena
   Wysocki, Michal
   Klos, Nikola
   Stefura, Tomasz
   Wojewoda, Tomasz
   Wysocki, Wojciech M.
TI Incisional Negative Pressure Wound Therapy Versus Primary Wound Suturing
   after Intestinal Ostomy Closure: A Systematic Review and Meta-Analysis
SO ADVANCES IN WOUND CARE
LA English
DT Article
DE negative pressure wound therapy; stoma closure; NPWT; primary wound
   suturing; meta-analysis
ID SURGICAL-SITE INFECTIONS; ENHANCED RECOVERY; HOSPITAL STAY; REVERSAL;
   REDUCE; SURGERY; RISK
AB Objective: Wound infection after intestinal ostomy closure is a very common postoperative complication. An alternative to primary wound suturing by single sutures or purse string sutures (PSS) is applying incisional negative pressure wound therapy (iNPWT). The aim of the following systematic review and meta-analysis was to assess and compare clinical outcomes in patients after PSS and iNPWT use. Approach: The aim of the study was to find relevant clinical data comparing outcomes of iNPWT and primary wound closure after intestinal ostomy closure. The search was conducted using the MEDLINE/PubMed, ScienceDirect, EMBASE, Scopus, Cochrane Controlled Register of Trials, SciELO, and Web of Science databases and took place up to November 12, 2022. The authors did not use date or language filters. Statistical analysis was performed using Review Manager 5.4 (The Cochrane Collaboration, 2020, London, UK). The authors conducted a meta-analysis of the following four parameters: wound healing time (WHT), surgical site infections (SSIs), complications, and length of hospital stay (LOS). Odds ratios (OR) and inverse variance (IV) were generated with 95% confidence intervals (CI). The meta-analysis was registered in the International Prospective Register of Systematic Reviews database under registration number CRD42023391640. Results: The analysis revealed that the iNPWT group and the control group did not differ significantly with regard to the WHT parameter (Z = 2,73; p = 0.006; chi(2) = 0.37, df = 1, p = 0.54, I-2 = 0%). Meta-analysis of SSI incidence revealed a significant difference favoring the iNPWT group over the observational group (OR = 0.42; 95% CI = 0.25-0.72; p = 0.002; I-2 = 14%). Patients included in the iNPWT group had a significantly lower pooled incidence of overall complications than the observational group (OR = 0.52; 95% CI = 0.35-0.77; p = 0.001, I-2 = 71%). Subgroup analysis limited to randomized studies also presented significant differences favoring the iNPWT group over the observational group (OR = 0.27; 95% CI = 0.14-0.52; p < 0.001, I-2 = 67%). Our analysis showed that LOS did not differ significantly between the groups treated with and without iNPWT (IV = 0.19; 95% CI = -0.66 -1,04; p = 0.76, I-2 = 0%). In addition, subgroup analysis of randomized studies also did not present a significant difference (IV = 0.25; 95% CI = -0.80 -1,30; p = 0.33, I-2 = 10%). Innovation: This study shows that the use of iNPWT can reduce the risk of SSIs with other complications, such as wound hematomas, wound seromas, wound dehiscence, fistulas, and ileus, in patients undergoing intestinal ostomy closure without extended hospital stay. Conclusions: Use of iNPWT can be considered in postoperative care after elective ostomy closure to decrease the rate of the most common complications after ostomy closure.
C1 [Kisielewski, Michal; Richter, Karolina; Klos, Nikola; Wojewoda, Tomasz; Wysocki, Wojciech M.] Andrzej Frycz Modrzewski Cracow Univ, Fac Med & Hlth Sci, Chair Surg, Krakow, Poland.
   [Kisielewski, Michal; Pisarska-Adamczyk, Magdalena] 5th Mil Clin Hosp, Dept Gen & Oncol Surg, Krakow, Poland.
   [Richter, Karolina] 5th Mil Clin Hosp, Krakow, Poland.
   [Pisarska-Adamczyk, Magdalena; Stefura, Tomasz] Jagiellonian Univ Med Coll, Dept Med Educ, Krakow, Poland.
   [Wysocki, Michal] Ludw Rydygier Mem Hosp, Dept Gen Surg & Surg Oncol, Krakow, Poland.
   [Klos, Nikola] Dist Hosp, Chrzanow, Poland.
   [Stefura, Tomasz] Ludw Rydygier Mem Hosp, Malopolska Ctr Burns & Plast Surg, Krakow, Poland.
   [Richter, Karolina; Wojewoda, Tomasz; Wysocki, Wojciech M.] 5th Mil Clin Hosp, Dept Oncol Surg, Wroclawska 1-3, PL-30901 Krakow, Poland.
   [Wysocki, Wojciech M.] Maria Sklodowska Curie Natl Res Inst Oncol, Warsaw, Poland.
C3 Andrzej Frycz Modrzewski Krakow University; Jagiellonian University;
   Collegium Medicum Jagiellonian University
RP Richter, K (通讯作者)，5th Mil Clin Hosp, Dept Oncol Surg, Wroclawska 1-3, PL-30901 Krakow, Poland.
EM karolinaa.richter@gmail.com
RI ; Stefura, Tomasz/CAA-5539-2022; Kisielewski, Michał/AAY-8327-2020;
   Pisarska-Adamczyk, Magdalena/ABD-7785-2020
OI Richter, Karolina/0000-0001-6151-0571; 
FU Andrzej Frycz Modrzewski Cracow University [WDPR/2024/03/00002,
   WSUB/2024/03/00002]
FX This study was supported by Andrzej Frycz Modrzewski Cracow University -
   grants WDPR/2024/03/00002 and WSUB/2024/03/00002.
CR Biancari F, 2022, J CLIN MED, V11, DOI 10.3390/jcm11154268
   Borejsza-Wysocki M, 2021, VIDEOSURGERY MINIINV, V16, P686, DOI 10.5114/wiitm.2021.106426
   Camperlengo L, 2023, SURG INFECT, V24, P382, DOI 10.1089/sur.2022.411
   Cantero R, 2016, ADV SKIN WOUND CARE, V29, P114, DOI 10.1097/01.ASW.0000480458.60005.34
   Carrano FM, 2021, BJS OPEN, V5, DOI 10.1093/bjsopen/zrab116
   Curchod P, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-11856-8
   Elsner AT, 2021, DIS COLON RECTUM, V64, P1398, DOI 10.1097/DCR.0000000000002182
   Faisal M, 2021, CANCERS, V13, DOI 10.3390/cancers13102482
   Forsmo HM, 2016, INT J SURG, V36, P121, DOI 10.1016/j.ijsu.2016.10.031
   Frodl A, 2022, EFORT OPEN REV, V7, P526, DOI 10.1530/EOR-22-0049
   Gachabayov M, 2019, TECH COLOPROCTOL, V23, P207, DOI 10.1007/s10151-019-01952-9
   Guyatt G., 2008, EVIDENCE BASED MED W
   Horesh N, 2018, TECH COLOPROCTOL, V22, P81, DOI 10.1007/s10151-017-1735-4
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Kay D, 2019, AM SURGEON, V85, P695
   Lee Jung Ryeol, 2011, J Korean Soc Coloproctol, V27, P58, DOI 10.3393/jksc.2011.27.2.58
   Luo DH, 2018, STAT METHODS MED RES, V27, P1785, DOI 10.1177/0962280216669183
   Manik M, 2024, ADV WOUND CARE, V13, P123, DOI 10.1089/wound.2023.0052
   Nie B, 2016, J WOUND CARE, V25, P617, DOI 10.12968/jowc.2016.25.11.617
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   Osterhoff G, 2014, J PLAST RECONSTR AES, V67, P629, DOI 10.1016/j.bjps.2014.01.010
   Page Matthew J, 2021, Int J Surg, V88, P105906, DOI [10.1016/j.rec.2021.07.010, 10.1016/j.ijsu.2021.105906]
   Pedziwiatr M, 2015, INT J SURG, V21, P75, DOI 10.1016/j.ijsu.2015.06.087
   Poehnert D, 2017, WOUND REPAIR REGEN, V25, P994, DOI 10.1111/wrr.12606
   Rondelli F, 2018, INT J SURG, V52, P208, DOI 10.1016/j.ijsu.2018.02.027
   Russo Mark W, 2007, Gastroenterol Hepatol (N Y), V3, P637
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Shao PL, 2021, INT J MOL SCI, V22, DOI 10.3390/ijms221910266
   Slieker J, 2018, TECH COLOPROCTOL, V22, P295, DOI 10.1007/s10151-018-1778-1
   St-Amour P, 2020, LANGENBECK ARCH SURG, V405, P959, DOI 10.1007/s00423-020-01981-1
   Uchino M, 2016, DIGEST SURG, V33, P449, DOI 10.1159/000446550
   Wan X, 2014, BMC MED RES METHODOL, V14, DOI 10.1186/1471-2288-14-135
   Wierdak M, 2021, TECH COLOPROCTOL, V25, P185, DOI 10.1007/s10151-020-02372-w
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Yane Y, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-05016-1
NR 35
TC 3
Z9 3
U1 0
U2 2
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD APR 1
PY 2025
VL 14
IS 4
BP 199
EP 209
DI 10.1089/wound.2024.0100
EA OCT 2024
PG 11
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 0UF9S
UT WOS:001337803500001
PM 39135388
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Mu, SC
   Hua, QQ
   Jia, YY
   Chen, MW
   Tang, YZ
   Deng, DT
   He, Y
   Zuo, CL
   Dai, F
   Hu, HL
AF Mu, Shichang
   Hua, Qiaoqiao
   Jia, Yangyang
   Chen, Ming-Wei
   Tang, Yizhong
   Deng, Datong
   He, Yong
   Zuo, Chunlin
   Dai, Fang
   Hu, Honglin
TI Effect of negative-pressure wound therapy on the circulating number of
   peripheral endothelial progenitor cells in diabetic patients with mild
   to moderate degrees of ischaemic foot ulcer
SO VASCULAR
LA English
DT Article
DE Diabetic foot ulcer; endothelial progenitor cell; negative-pressure
   wound therapy; cytokines
ID MOBILIZATION; MANAGEMENT; INFECTION
AB Objective To investigate the effect of negative-pressure wound therapy (NPWT) on the circulating number of endothelial progenitor cells (EPCs) in diabetic patients with mild to moderate degrees of ischemic foot ulcer. Methods We selected 84 diabetic patients who had a foot ulcer with a duration of at least four weeks and who had an ankle-brachial index of 0.5-0.9. Patients were assigned to one two groups according to 2:1 randomization: NPWT group (n = 56) and non-NPWT (patients who did not receive NPWT) group (n = 28). The control group (NC group) was composed of 18 patients who had normal glucose tolerance and lower extremity ulcer without arteriovenous disease. NPWT was performed on the ulcer after debridement for one week for patients in both the NPWT group and the NC group, and the patients in the non-NPWT group received conventional treatment process. The circulating number of EPCs was measured before and after various treatments, and the factors influencing their changes were analysed. Results After NPWT, the circulating number of EPCs significantly increased in both the NPWT group and the NC group ((85.3 +/- 18.1) vs. (34.1 +/- 12.5)/10(6) cells; (119.9 +/- 14.4) vs. (66.1 +/- 10.6)/10(6) cells, both P < 0.05). In contrast, the circulating number of EPCs had no significant change in the non-NPWT group ((45.2 +/- 19.4) vs. (34.7 +/- 16.8)/10(6) cells, P > 0.05). In addition, the circulating levels of vascular endothelial growth factor (VEGF) and the protein expressions of VEGF and stromal cell-derived factor-1 alpha (SDF-1 alpha) in the granulation tissue significantly increased after NPWT in both the NPWT and the NC group, but there was no significant change in the non-NPWT group. Compared with the non-NPWT group, the changes in VEGF and SDF-1 alpha levels in the sera and granulation tissue were all significantly higher in both the NPWT and NC groups (P < 0.05, P < 0.01, respectively). There was no significant difference in changes in the circulating number of EPCs in the peripheral blood and levels of VEGF and SDF-1 alpha in the sera and granulation tissue between the NPWT and NC groups. Correlation analysis showed that the change in the circulating number of EPCs was correlated with the changes of VEGF and SDF-1 alpha levels in the sera and granulation of the NPWT and NC groups (P < 0.05). Conclusion NPWT may increase the circulating number of EPCs in diabetic patients with mild to moderate ischaemic foot ulcer as in non-diabetic controls, which may be attributed to the upregulation of systemic and local VEGF and SDF-1 alpha levels.
C1 [Mu, Shichang; Hua, Qiaoqiao; Jia, Yangyang; Chen, Ming-Wei; Deng, Datong; He, Yong; Zuo, Chunlin; Dai, Fang; Hu, Honglin] Anhui Med Univ, Affiliated Hosp 1, Dept Endocrinol, Jixi Rd 218, Hefei 230032, Anhui, Peoples R China.
   [Chen, Ming-Wei] Acad Tradit Chinese Med, Inst Diabet Prevent & Control, Hefei, Anhui, Peoples R China.
   [Tang, Yizhong] Anhui Med Univ, Affiliated Hosp 1, Dept Burns, Hefei, Anhui, Peoples R China.
C3 Anhui Medical University; Anhui Medical University
RP Chen, MW (通讯作者)，Anhui Med Univ, Affiliated Hosp 1, Dept Endocrinol, Jixi Rd 218, Hefei 230032, Anhui, Peoples R China.; Chen, MW (通讯作者)，Acad Tradit Chinese Med, Inst Diabet Prevent & Control, Hefei, Anhui, Peoples R China.
EM chmw1@163.com
RI Jia, yang/HTN-3694-2023
FU Clinical Medical Special Foundation of Chinese Society [13061050490]
FX The author(s) disclosed receipt of the following financial support for
   the research, authorship, and/or publication of this article: Funding
   for this project was provided by Clinical Medical Special Foundation of
   Chinese Society (13061050490).
CR Adeghate J, 2017, EXPERT OPIN BIOL TH, V17, P979, DOI 10.1080/14712598.2017.1333596
   Anderson EM, 2015, J VASC RES, V52, P62, DOI 10.1159/000382129
   Anderson EM, 2015, TISSUE ENG PT A, V21, P1217, DOI [10.1089/ten.tea.2014.0508, 10.1089/ten.TEA.2014.0508]
   Asai J, 2013, INT WOUND J, V10, P527, DOI 10.1111/j.1742-481X.2012.01010.x
   Barcelos LS, 2009, CIRC RES, V104, P1095, DOI 10.1161/CIRCRESAHA.108.192138
   Bongiovanni D, 2014, STEM CELLS DEV, V23, P2403, DOI 10.1089/scd.2014.0111
   Braun LR, 2014, AM J CLIN DERMATOL, V15, P267, DOI 10.1007/s40257-014-0081-9
   Broz P, 2015, CLIN HEMORHEOL MICRO, V60, P263, DOI 10.3233/CH-131676
   Everaert BR, 2010, INT J CARDIOL, V144, P350, DOI 10.1016/j.ijcard.2010.04.018
   Everett E, 2018, ANN NY ACAD SCI, V1411, P153, DOI 10.1111/nyas.13569
   Gemechu FW, 2013, AM FAM PHYSICIAN, V88, P177
   Hasan MY, 2015, DIABET FOOT ANKLE, V6, DOI 10.3402/dfa.v6.27618
   Jiang YF, 2015, WOUND REPAIR REGEN, V23, P222, DOI 10.1111/wrr.12263
   King Thomas F J, 2014, J Stem Cells, V9, P93
   Labler L, 2006, ZBL CHIR, V131, pS62
   Lee DY, 2008, BONE, V42, P932, DOI 10.1016/j.bone.2008.01.007
   Lin LY, 2014, CARDIOVASC DIABETOL, V13, DOI 10.1186/s12933-014-0111-1
   Liu S, 2017, THER CLIN RISK MANAG, V13, DOI 10.2147/TCRM.S131193
   Menegazzo L, 2012, BIOFACTORS, V38, P194, DOI 10.1002/biof.1016
   Nain Prabhdeep Singh, 2011, J Surg Tech Case Rep, V3, P17, DOI 10.4103/2006-8808.78466
   Peters EJG, 2013, MED CLIN N AM, V97, P911, DOI 10.1016/j.mcna.2013.04.005
   Piatkowski A, 2013, INT REV CEL MOL BIO, V306, P43, DOI 10.1016/B978-0-12-407694-5.00002-X
   Sajid MT, 2015, JCPSP-J COLL PHYSICI, V25, P789, DOI 11.2015/JCPSP.789793
   Schintler MV, 2012, DIABETES-METAB RES, V28, P72, DOI 10.1002/dmrr.2243
   Seo SG, 2013, EXP MOL MED, V45, DOI 10.1038/emm.2013.129
   Tanaka T, 2016, EUR J PLAST SURG, V39, P247, DOI 10.1007/s00238-016-1200-z
   Tecilazich F, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0083314
   Wang RR, 2015, INT J CLIN EXP MED, V8, P12548
   Wang WY, 2014, EXP THER MED, V7, P1221, DOI 10.3892/etm.2014.1567
   Yu JX, 2009, J VASC SURG, V50, P608, DOI 10.1016/j.jvs.2009.05.049
   Zan T, 2015, CELL BIOCHEM FUNCT, V33, P143, DOI 10.1002/cbf.3091
NR 31
TC 16
Z9 18
U1 0
U2 5
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1708-5381
EI 1708-539X
J9 VASCULAR
JI Vascular
PD AUG
PY 2019
VL 27
IS 4
BP 381
EP 389
DI 10.1177/1708538119836360
PG 9
WC Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA IK3ZE
UT WOS:000476526100007
PM 30841790
DA 2026-07-24
ER

PT J
AU Frykberg, R
   Martin, E
   Tallis, A
   Tierney, E
AF Frykberg, Robert
   Martin, Erin
   Tallis, Arthur
   Tierney, Edward
TI A case history of multimodal therapy in healing a complicated diabetic
   foot wound: negative pressure, dermal replacement and pulsed radio
   frequency energy therapies
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Complex wound; Diabetic foot; Multimodal therapies
ID CELL-PROLIFERATION INDUCTION; MECHANISMS; CLOSURE
AB Advanced multimodal therapies are being used with increasing frequency in the management of difficult or complex wounds. Although the primary goal remains to expedite complete healing, secondary goals include avoidance of superimposed infection, repeated hospitalisations and subsequent amputations. We describe a case involving a limb- and life-threatening necrotising infection in a diabetic patient in which we successfully applied negative pressure wound therapy, dermal replacement therapy and pulsed radio frequency energy to achieve definitive healing. Further study is warranted to elucidate the most effective combinations of such therapies to promote healing of similarly complex wounds.
C1 [Frykberg, Robert; Martin, Erin; Tallis, Arthur; Tierney, Edward] Carl T Hayden VA Med Ctr, Phoenix, AZ 85012 USA.
RP Frykberg, R (通讯作者)，Carl T Hayden VA Med Ctr, 650 E Indian Sch Rd, Phoenix, AZ 85012 USA.
EM Robert.frykberg@va.gov
CR Andros G, 2006, OSTOMY WOUND MANAG, P1
   [Anonymous], 2009, NEGATIVE PRESSURE WO
   Bahebeck J, 2010, J FOOT ANKLE SURG, V49, P43, DOI 10.1053/j.jfas.2009.08.011
   Bollero D, 2010, OSTOMY WOUND MANAG, P4
   CLEARY SF, 1990, BIOELECTROMAGNETICS, V11, P47, DOI 10.1002/bem.2250110107
   Dworkin MS, 2009, EPIDEMIOL INFECT, V137, P1609, DOI 10.1017/S0950268809002532
   Frykberg R.G., 2006, J FOOT ANKLE SURG, V45, pS2
   Frykberg R, 2009, INT J LOW EXTR WOUND, V8, P45, DOI 10.1177/1534734608329783
   George FR, 2002, WOUNDS, V14, P107
   Gilbert TL, 2002, ANN NY ACAD SCI, V961, P168, DOI 10.1111/j.1749-6632.2002.tb03076.x
   JAIN A, 2009, J DIABETIC FOOT COMP, V1, P80
   Larsen JA, 2008, J WOUND OSTOMY CONT, V35, P523, DOI 10.1097/01.WON.0000335966.98607.1c
   Lipsky BA, 2006, PLAST RECONSTR SURG, V117, p212S, DOI 10.1097/01.prs.0000222737.09322.77
   Liu Yuag-Meng, 2005, Journal of Microbiology Immunology and Infection, V38, P430
   Marston WA, 2004, EXPERT REV MED DEVIC, V1, P21, DOI 10.1586/17434440.1.1.21
   MOFFETT JGN, 2008, S ADV WOUND CAR SAN
   Naughton G, 1997, ARTIF ORGANS, V21, P1203
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Sheehan P, 2003, DIABETES CARE, V26, P1879, DOI 10.2337/diacare.26.6.1879
   Snyder Robert J, 2010, Ostomy Wound Manage, V56, pS1
   SUMIO B, 2009, WOUNDS S, P1
   VOROS D, 1993, BRIT J SURG, V80, P1190, DOI 10.1002/bjs.1800800943
   WANG KC, 1992, J TRAUMA, V32, P179, DOI 10.1097/00005373-199202000-00011
   Younger ASE, 2009, FOOT ANKLE INT, V30, P1177, DOI 10.3113/FAI.2009.1177
   Zgonis T., 2008, AORN J, V87, P947
   Zgonis Thomas, 2008, AORN J, V87, P935, DOI 10.1016/j.aorn.2008.02.014
NR 26
TC 13
Z9 13
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2011
VL 8
IS 2
BP 132
EP 139
DI 10.1111/j.1742-481X.2010.00759.x
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 735YW
UT WOS:000288457700007
PM 21348945
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Gonzalez, KW
   Chandler, NM
AF Gonzalez, Katherine W.
   Chandler, Nicole M.
TI Ruptured omphalocele: Diagnosis and management
SO SEMINARS IN PEDIATRIC SURGERY
LA English
DT Article
DE Omphalocele; Rupture; Giant; Surgery
ID ABDOMINAL-WALL RECONSTRUCTION; GIANT OMPHALOCELES; GASTROSCHISIS;
   OUTCOMES; THERAPY; INFANTS; MATRIX
AB Omphalocele is an abdominal wall defect which can be classified as small, giant, or ruptured. Ruptured omphaloceles require prompt diagnosis and management to prevent associated morbidity and mortality and represent a challenging surgical condition. This review serves to define the etiology, diagnosis, initial resuscitation, and surgical therapy employed in the treatment of ruptured omphalocele. Resuscitation should focus on maintaining hydration and normothermia. Broad spectrum antibiotics should be initiated. Similar to giant omphaloceles, procedural intervention includes primary closure, silo, synthetic and biologic mesh, negative pressure wound therapy, and topical agents. Despite advances in neonatal care, the prognosis remains guarded and mortality is high. (C) 2019 Elsevier Inc. All rights reserved.
C1 [Gonzalez, Katherine W.; Chandler, Nicole M.] Johns Hopkins All Childrens Hosp, Dept Surg, 501 6th Ave S, St Petersburg, FL 33701 USA.
C3 Johns Hopkins University; Johns Hopkins Medicine
RP Chandler, NM (通讯作者)，Johns Hopkins All Childrens Hosp, Dept Surg, 501 6th Ave S, St Petersburg, FL 33701 USA.
EM nicole.chandler@jhmi.edu
OI Gonzalez, Katherine/0000-0002-5400-5291
CR Akinkuotu AC, 2015, J SURG RES, V198, P388, DOI 10.1016/j.jss.2015.03.060
   Aldridge B, 2016, AM J SURG, V211, P605, DOI 10.1016/j.amjsurg.2015.11.009
   Bauman B, 2016, J PEDIATR SURG, V51, P1725, DOI 10.1016/j.jpedsurg.2016.07.006
   Begum T, 2016, J PEDIATR SURG, V51, P461, DOI 10.1016/j.jpedsurg.2015.10.083
   Betat RD, 2014, AM J MED GENET A, V164, P559, DOI 10.1002/ajmg.a.36289
   Binet A, 2013, J PLAST RECONSTR AES, V66, pE373, DOI 10.1016/j.bjps.2013.05.010
   Bode CO, 2018, NIGER POSTGRAD MED J, V25, P48, DOI 10.4103/npmj.npmj_159_17
   Corey KM, 2014, EARLY HUM DEV, V90, P421, DOI 10.1016/j.earlhumdev.2014.05.006
   Diemon N, 2017, ARCH GYNECOL OBSTET, V295, P325, DOI 10.1007/s00404-016-4236-1
   Haug S, 2016, J PEDIAT GASTROENTER
   Ionescu S, 2014, CHIRURGIA-BUCHAREST, V109, P7
   Kelly KB, 2013, SURG CLIN N AM, V93, P1255, DOI 10.1016/j.suc.2013.06.016
   Levy S, 2013, J PEDIATR SURG, V48, P2525, DOI 10.1016/j.jpedsurg.2013.05.067
   Marshall J, 2015, OBSTET GYNECOL, V126, P284, DOI 10.1097/AOG.0000000000000920
   Naji H, 2014, EUR J PEDIATR SURG, V24, P94, DOI 10.1055/s-0033-1354587
   Oquendo M, 2015, J PEDIATR SURG, V50, P1668, DOI 10.1016/j.jpedsurg.2015.06.011
   Peters NCJ, 2014, EUR J OBSTET GYN R B, V181, P294, DOI 10.1016/j.ejogrb.2014.08.009
   Roux N, 2018, J PEDIAT SURG
   Saxena AK, 2018, MINERVA PEDIATR, V70, P289, DOI 10.23736/S0026-4946.17.05109-X
   Tarca E, 2014, CHIRURGIA-BUCHAREST, V109, P507
   Travassos DV, 2015, EUR J PEDIATR SURG R, V3, P61, DOI 10.1055/s-0035-1549364
   Watanabe S, 2017, J NEONATAL SURG, V6, P27, DOI DOI 10.21699/JNS
   Zmora O, 2017, AM J SURG, V214, P479, DOI 10.1016/j.amjsurg.2017.01.004
NR 23
TC 25
Z9 39
U1 0
U2 4
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1055-8586
EI 1532-9453
J9 SEMIN PEDIATR SURG
JI Semin. Pediatr. Surg.
PD APR
PY 2019
VL 28
IS 2
BP 101
EP 105
DI 10.1053/j.sempedsurg.2019.04.009
PG 5
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA HY8HI
UT WOS:000468377600006
PM 31072456
DA 2026-07-24
ER

PT J
AU Ingemansson, R
   Malmsjö, M
   Lindstedt, S
AF Ingemansson, Richard
   Malmsjo, Malin
   Lindstedt, Sandra
TI A Protective Device for Negative-Pressure Therapy in Patients With
   Mediastinitis
SO ANNALS OF THORACIC SURGERY
LA English
DT Editorial Material
ID PREVENT HEART RUPTURE; WOUND THERAPY; RIGID BARRIER; DRAINAGE
AB A devastating complication associated with negative-pressure wound therapy (NPWT) after cardiac surgical intervention is heart rupture resulting in serious bleeding. The benefit of a rigid barrier between the underlying organs and the sharp sternal edges has been demonstrated in pigs. In the present article, we present our first 6 patients with deep sternal wound infection treated with NPWT in combination with a protective device. The median duration of NPWT was 8 days (range, 6-14 days). No major bleeding or signs of organ damage were observed. The use of a protective device seems to decrease the risk of bleeding complications. (Ann Thorac Surg 2013;95:362-4) (C) 2013 by The Society of Thoracic Surgeons
C1 [Ingemansson, Richard] Lund Univ, Skane Univ Hosp, Heart & Lung Ctr, Dept Cardiothorac Surg, SE-22185 Lund, Sweden.
   Lund Univ, Skane Univ Hosp, Dept Ophthalmol, SE-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital
RP Ingemansson, R (通讯作者)，Lund Univ, Skane Univ Hosp, Heart & Lung Ctr, Dept Cardiothorac Surg, SE-22185 Lund, Sweden.
EM richard.ingemansson@skane.se
RI ; Lindstedt, Sandra/AEM-2892-2022
OI Maljö, Malin/0000-0001-9849-9599; Ingemansson,
   Richard/0000-0001-7623-8953; Lindstedt, Sandra/0000-0003-4484-6473
CR Abu-Omar Y, 2003, ANN THORAC SURG, V76, P974, DOI 10.1016/S0003-4975(03)00180-2
   Khoynezhad A, 2004, J CARDIAC SURG, V19, P74, DOI 10.1111/j.0886-0440.2004.04015.x
   Lindstedt S, 2011, INT WOUND J, V8, P454, DOI 10.1111/j.1742-481X.2011.00816.x
   Lindstedt S, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-90
   Lindstedt S, 2011, INT WOUND J, V8, P385, DOI 10.1111/j.1742-481X.2011.00803.x
   Lindstedt S, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-42
   U.S. Food and Drug Administration, 2009, FDA PREL PUBL HLTH N
   US Food and Drug Administration, 2011, FDA PREL PUBL HLTH N
NR 8
TC 10
Z9 11
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
EI 1552-6259
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD JAN
PY 2013
VL 95
IS 1
BP 362
EP 364
DI 10.1016/j.athoracsur.2012.08.027
PG 3
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 068DC
UT WOS:000313343700074
PM 23272868
DA 2026-07-24
ER

PT J
AU Jiang, Y
   He, S
AF Jiang, Yao
   He, Shan
TI Case Report: A review of two children with deep sternal wound infections
   after precordial surgery treated with a simple negative pressure closed
   drainage technique
SO FRONTIERS IN PEDIATRICS
LA English
DT Article
DE negative pressure; pediatric; congenital heart; deep sternal wound
   infection; treatment
ID VACUUM-ASSISTED CLOSURE; MEDIASTINITIS
AB Deep sternal wound infection (DSWI) is a rare but potentially devastating complication of median sternotomy performed in cardiac surgery. This report summarizes the nursing management of two pediatric cases with a DSWI treated using Do It Yourself (DIY) negative pressure suction (DIY-NPS) after surgery. The technique maintains a continuous suction pressure of 75 mmHg and intermittently flushes small volumes of fluid to stimulate granulation tissue formation and control systemic infection. After the formation of fresh granulation tissue, both patients achieved successful wound healing and were discharged in good condition.
C1 [Jiang, Yao; He, Shan] Chongqing Med Univ, Childrens Hosp, Dept PICU Pediat Res Inst, Chongqing, Peoples R China.
   [Jiang, Yao; He, Shan] Natl Clin Res Ctr Child Hlth & Disorders, Chongqing Key Lab Pediat, China Int Sci & Technol Cooperat Base Child Dev &, Minist Educ,Key Lab Child Dev & Disorders, Chongqing, Peoples R China.
C3 Chongqing Medical University
RP He, S (通讯作者)，Chongqing Med Univ, Childrens Hosp, Dept PICU Pediat Res Inst, Chongqing, Peoples R China.; He, S (通讯作者)，Natl Clin Res Ctr Child Hlth & Disorders, Chongqing Key Lab Pediat, China Int Sci & Technol Cooperat Base Child Dev &, Minist Educ,Key Lab Child Dev & Disorders, Chongqing, Peoples R China.
EM 18883367709@163.com
FX The author(s) declare that no financial support was received for the
   research, authorship, and/or publication of this article.
CR Chen WM., 2018, Mod Clin Nurs, V17, P57, DOI [10.3969/j.issn.1671-8283.2018.02.012, DOI 10.3969/J.ISSN.1671-8283.2018.02.012]
   Chinese Burn Association of Chinese Medical Association, 2017, Chinese J Burns, V33, P129
   Filippelli S, 2015, J CARDIAC SURG, V30, P190, DOI 10.1111/jocs.12463
   Jiang Q-x., 2018, Theory and Practice of Negative Pressure Closure Wound Therapy
   Jiang Y., 2020, Chin J Acute Crit Care, V6, P558, DOI [10.3761/j.issn.2096-7446.2020.06.017, DOI 10.3761/J.ISSN.2096-7446.2020.06.017]
   Jo T, 2022, THORAC CARDIOV SURG, V70, P56, DOI 10.1055/s-0040-1722733
   Kadohama T, 2008, ANN THORAC SURG, V85, P1094, DOI 10.1016/j.athoracsur.2007.09.004
   Lin Y., 2020, J Clin Pediatr Surg, V19, P4
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Renish M K, 2023, Eplasty, V23, pe73
   Salazard B, 2008, J PLAST RECONSTR AES, V61, P302, DOI 10.1016/j.bjps.2007.05.004
   Swanson T, 2022, J WOUND CARE, V31, pS10, DOI 10.12968/jowc.2022.31.Sup12.S10
   Vicchio M, 2007, J THORAC CARDIOV SUR, V134, P254, DOI 10.1016/j.jtcvs.2007.03.024
   von Stumm M, 2022, PLOS ONE, V17, DOI 10.1371/journal.pone.0267985
   Wang W-P., 2013, Pediatrics
   Wei RL., 2021, Colorectal Anal Surg, V3, P280, DOI [10.19668/j.cnki.issn1674-0491.2021.03.025, DOI 10.19668/J.CNKI.ISSN1674-0491.2021.03.025]
   Wu L., 2020, SE Defense Med, V22, P300
   Wu YH, 2021, ARTIF ORGANS, V45, P827, DOI 10.1111/aor.13936
   Zhan HB, 2019, Chin J Injury Repair and Wound Healing(Electronic Edition), V14, P208, DOI [10.3877/cma.j.issn.1673-9450.2019.03.008, 10.3877/cma.j.issn.1673-9450.2019.03.008, DOI 10.3877/CMA.J.ISSN.1673-9450.2019.03.008]
NR 19
TC 0
Z9 0
U1 0
U2 2
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-2360
J9 FRONT PEDIATR
JI Front. Pediatr.
PD DEC 11
PY 2024
VL 12
AR 1491944
DI 10.3389/fped.2024.1491944
PG 4
WC Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics
GA Q1L8Q
UT WOS:001382395800001
PM 39722774
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Chester, DL
   Waters, R
AF Chester, DL
   Waters, R
TI Adverse alteration of wound flora with topical negative-pressure
   therapy: a case report
SO BRITISH JOURNAL OF PLASTIC SURGERY
LA English
DT Article
DE topical negative pressure; anaerobes; wound infection; inguinal block
   dissection
ID VACUUM-ASSISTED CLOSURE; DRESSINGS; PROMOTE
AB Topical negative pressure (TNP) has achieved widespread use in the treatment of problematic wounds. We report the case of a patient treated with TNP for Groin-wound dehiscence following inguinal block dissection. During treatment, clinical signs of sepsis developed, in association with a progressively worsening anaerobic wound infection. This infection settled with antibiotic therapy and cessation of TNP treatment. We postulate that the air-free environment created by TNP potentiated the Growth of the anaerobic bacteria, resulting in significant sepsis, and therefore recommend close surveillance of bacterial flora while using this therapy, particularly in susceptible patients. (C) 2002 The British Association of Plastic Surgeons.
C1 Univ Hosp Birmingham, Selly Oak Hosp, NHS Trust, Dept Plast Surg, Birmingham B29 6JD, W Midlands, England.
C3 University of Birmingham
RP Chester, DL (通讯作者)，Univ Hosp Birmingham, Selly Oak Hosp, NHS Trust, Dept Plast Surg, Raddlebarn Rd,Selly Oak, Birmingham B29 6JD, W Midlands, England.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Banwell P, 1998, BRIT J PLAST SURG, V51, P79, DOI 10.1016/S0007-1226(98)80142-2
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Elwood ET, 2001, ANN PLAS SURG, V46, P49, DOI 10.1097/00000637-200101000-00010
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   Gwan-Nulla DN, 2001, ANN PLAS SURG, V47, P552, DOI 10.1097/00000637-200111000-00014
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
NR 8
TC 39
Z9 52
U1 0
U2 2
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE,
   LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0007-1226
J9 BRIT J PLAST SURG
JI Br. J. Plast. Surg.
PD SEP
PY 2002
VL 55
IS 6
BP 510
EP 511
DI 10.1054/bjps.2002.3890
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 601RW
UT WOS:000178462600010
PM 12479427
OA Bronze
DA 2026-07-24
ER

PT J
AU Henry, SL
   Weinfeld, AB
   Sharma, SK
   Kelley, PK
AF Henry, Steven L.
   Weinfeld, Adam B.
   Sharma, Sanjay K.
   Kelley, Patrick K.
TI External Doppler Monitoring of Free Flaps through Negative Pressure
   Dressings
SO JOURNAL OF RECONSTRUCTIVE MICROSURGERY
LA English
DT Article
DE Free flap; monitoring; wound VAC
ID VACUUM-ASSISTED CLOSURE; SKIN-GRAFTS
AB The negative pressure dressing is a highly effective modality for coverage and bolstering of skin grafts in the early postoperative period. In the situation of a skin graft over a free flap, the surgeon might be inclined to avoid this modality out of concern that the dressing would deleteriously effect flap survival or impede flap monitoring. This case series supports the safety of the negative pressure dressing and demonstrates a technical modification that permits external Doppler monitoring of the flap through the dressing. Thus, this technique provides an ideal environment for skin graft healing while maintaining the ability to monitor the flap in a straightforward manner and also simplifies nursing care.
C1 [Henry, Steven L.; Weinfeld, Adam B.; Sharma, Sanjay K.; Kelley, Patrick K.] Dell Childrens Med Ctr Cent Texas, Univ Med Ctr Brackenridge, Seton Inst Reconstruct Plast Surg, Austin, TX USA.
RP Henry, SL (通讯作者)，1400 N IH 35,Ste 320, Austin, TX 78701 USA.
EM slhenry@seton.org
RI Sharma, Sanjeev Kumar/HTN-7624-2023
OI Sharma, Sanjeev Kumar/0000-0002-3273-0708
CR Bannasch H, 2008, MICROSURG, V28, P412, DOI 10.1002/micr.20512
   Hanasono MM, 2007, ANN PLAS SURG, V58, P573, DOI 10.1097/01.sap.0000237638.93453.66
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P601, DOI 10.1097/PRS.0b013e318196b97b
   Moisidis E, 2004, PLAST RECONSTR SURG, V114, P917, DOI 10.1097/01.PRS.0000133168.57199.E1
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Weinfeld AB, 2005, ANN PLAS SURG, V54, P178, DOI 10.1097/01.sap.0000143606.39693.3f
NR 6
TC 9
Z9 10
U1 0
U2 2
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 0743-684X
J9 J RECONSTR MICROSURG
JI J. Reconstr. Microsurg.
PD MAY
PY 2011
VL 27
IS 4
BP 215
EP 218
DI 10.1055/s-0031-1272962
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 753OL
UT WOS:000289788800002
PM 21337298
DA 2026-07-24
ER

PT J
AU Beddy, D
   Dozois, EJ
   Pemberton, JH
AF Beddy, David
   Dozois, Eric J.
   Pemberton, John H.
TI Perioperative Complications in Inflammatory Bowel Disease
SO INFLAMMATORY BOWEL DISEASES
LA English
DT Review
DE inflammatory bowel disease; surgery; perioperative complications
ID POUCH-ANAL ANASTOMOSIS; PERSISTENT PERINEAL SINUS; ULCERATIVE-COLITIS
   PATIENTS; PRIVATE HEALTH-INSURANCE; VACUUM-ASSISTED CLOSURE; PORTAL-VEIN
   THROMBI; SHORT-TERM OUTCOMES; TO-END ANASTOMOSIS; QUALITY-OF-LIFE;
   CROHNS-DISEASE
AB Almost 50% of patients with inflammatory bowel disease (IBD) will undergo surgery for their disease at some stage of its clinical course. Complications seen following surgery may occur early or late in the postoperative period. Patient factors, including active inflammatory disease, malnutrition, and use of immunosuppressant medications, make these patients a challenging surgical group and at increased risk for surgical complications. The purpose of this review is to characterize the complications that are commonly seen following surgery in patients with IBD and to discuss the surgical and patient factors that may influence their development.
C1 [Beddy, David; Dozois, Eric J.; Pemberton, John H.] Mayo Clin, Div Colon & Rectal Surg, Rochester, MN 55905 USA.
C3 Mayo Clinic
RP Pemberton, JH (通讯作者)，Mayo Clin, Div Colorectal Surg, 200 1st St SW, Rochester, MN 55905 USA.
EM pemberton.john@mayo.edu
CR Abcarian H, 1997, SURGERY, V122, P688
   Aberra FN, 2003, GASTROENTEROLOGY, V125, P320, DOI 10.1016/S0016-5085(03)00883-7
   Appau KA, 2008, J GASTROINTEST SURG, V12, P1738, DOI 10.1007/s11605-008-0646-0
   BAKER K, 1989, ALIMENT PHARM THER, V3, P143
   Ball CG, 2007, SURG TODAY, V37, P552, DOI 10.1007/s00595-006-3470-8
   Bergamaschi R, 2003, DIS COLON RECTUM, V46, P1129, DOI 10.1007/s10350-004-7292-8
   Canin-Endres J, 1999, SURG ENDOSC-ULTRAS, V13, P595, DOI 10.1007/s004649901049
   CARTER FM, 1991, DIS COLON RECTUM, V34, P1005, DOI 10.1007/BF02049965
   Chapman JR, 2005, ARCH SURG-CHICAGO, V140, P534, DOI 10.1001/archsurg.140.6.534
   Cima Robert R, 2007, Clin Colon Rectal Surg, V20, P336, DOI 10.1055/s-2007-991034
   Colombel JF, 2004, AM J GASTROENTEROL, V99, P878, DOI 10.1111/j.1572-0241.2004.04148.x
   Colombel JF, 2003, AM J GASTROENTEROL, V98, P2239, DOI 10.1016/S0002-9270(03)00660-9
   EHRLICH HP, 1968, ANN SURG, V167, P324, DOI 10.1097/00000658-196803000-00004
   Farouk R, 1998, DIS COLON RECTUM, V41, P1239, DOI 10.1007/BF02258220
   Ferrante M, 2009, INFLAMM BOWEL DIS, V15, P1062, DOI 10.1002/ibd.20863
   Fichera A, 2003, DIS COLON RECTUM, V46, P643, DOI 10.1007/s10350-004-6625-y
   Fry RD, 2004, ANN SURG, V240, P621
   FURST MB, 1994, DIS COLON RECTUM, V37, P12, DOI 10.1007/BF02047207
   Gorgun E, 2005, COLORECTAL DIS, V7, P545, DOI 10.1111/j.1463-1318.2005.00895.x
   GREENSTEIN AJ, 1975, NEW ENGL J MED, V293, P685, DOI 10.1056/NEJM197510022931403
   Hahnloser D, 2007, BRIT J SURG, V94, P333, DOI 10.1002/bjs.5464
   Hahnloser D, 2004, ANN SURG, V240, P615, DOI 10.1097/01.sla.0000141157.32234.9d
   Hahnloser D, 2004, DIS COLON RECTUM, V47, P1127, DOI 10.1007/s10350-004-0569-0
   Hahnloser D, 2003, SURG ENDOSC, V17, P238
   Halverson AL, 2001, SURGERY, V130, P772
   Holubar SD, 2009, DIS COLON RECTUM, V52, P1815, DOI 10.1007/DCR.0b013e3181b327a6
   Hudson M, 1997, INT J GYNECOL OBSTET, V58, P229, DOI 10.1016/S0020-7292(97)00088-X
   HULL MGR, 1985, BMJ-BRIT MED J, V291, P1693, DOI 10.1136/bmj.291.6510.1693
   Hurst RD, 2001, SURGERY, V130, P767, DOI 10.1067/msy.2001.117100
   Hyde GM, 1998, EUR J GASTROEN HEPAT, V10, P411, DOI 10.1097/00042737-199805000-00010
   Hyde GM, 2001, DIS COLON RECTUM, V44, P1436, DOI 10.1007/BF02234594
   Indar AA, 2009, WORLD J SURG, V33, P1049, DOI 10.1007/s00268-009-9957-x
   Kaiser AM, 2008, J GASTROINTEST SURG, V12, P1736
   KOENIGS KP, 1987, J CLIN GASTROENTEROL, V9, P627
   Kunitake H, 2008, J GASTROINTEST SURG, V12, P1730, DOI 10.1007/s11605-008-0630-8
   KYLE SM, 1992, AUST NZ J SURG, V62, P196, DOI 10.1111/j.1445-2197.1992.tb05462.x
   LANGHOLZ E, 1992, GASTROENTEROLOGY, V103, P1444, DOI 10.1016/0016-5085(92)91163-X
   LANGHOLZ E, 1994, GASTROENTEROLOGY, V107, P3, DOI 10.1016/0016-5085(94)90054-X
   Larson DW, 2008, DIS COLON RECTUM, V51, P392, DOI 10.1007/s10350-007-9180-5
   Larson DW, 2006, ANN SURG, V243, P667, DOI 10.1097/01.sla.0000216762.83407.d2
   LAVERY IC, 1995, DIS COLON RECTUM, V38, P803, DOI 10.1007/BF02049836
   LEIJONMARCK CE, 1990, ACTA CHIR SCAND, P1
   Lepistö A, 2007, BRIT J SURG, V94, P478, DOI 10.1002/bjs.5509
   Lim M, 2007, DIS COLON RECTUM, V50, P943, DOI 10.1007/s10350-007-0246-1
   Loftus EV, 2008, AM J GASTROENTEROL, V103, P1737, DOI 10.1111/j.1572-0241.2008.01867.x
   Loftus EV, 2009, INFLAMM BOWEL DIS, V15, P566, DOI 10.1002/ibd.20810
   Loftus EV Jr, 1998, GASTROENTEROLOGY, V114, P1161, DOI 10.1016/S0016-5085(98)70421-4
   Lohsiriwat V, 2009, SURG TODAY, V39, P189, DOI 10.1007/s00595-008-3846-z
   Maartense S, 2006, ANN SURG, V243, P143, DOI 10.1097/01.sla.0000197318.37459.ec
   MacLean AR, 2002, ANN SURG, V235, P200, DOI 10.1097/00000658-200202000-00007
   Mahadevan U, 2002, INFLAMM BOWEL DIS, V8, P311, DOI 10.1097/00054725-200209000-00001
   Marchal L, 2004, ALIMENT PHARM THER, V19, P749, DOI 10.1111/j.1365-2036.2004.01904.x
   Mathis KL, 2009, ANN SURG, V249, P409, DOI 10.1097/SLA.0b013e31819a697b
   Matzke GM, 2004, DIS COLON RECTUM, V47, P782, DOI 10.1007/s10350-003-0105-7
   MCKEE RF, 1995, INT J COLORECTAL DIS, V10, P222, DOI 10.1007/BF00346223
   McLeod RS, 2009, DIS COLON RECTUM, V52, P919, DOI 10.1007/DCR.0b013e3181a4fa58
   Millan M, 2007, DIS COLON RECTUM, V50, P1540, DOI 10.1007/s10350-007-0297-3
   Mor IJ, 2008, DIS COLON RECTUM, V51, P1202, DOI 10.1007/s10350-008-9364-7
   Muñoz-Juárez M, 2001, DIS COLON RECTUM, V44, P20, DOI 10.1007/BF02234814
   NELSON H, 1989, DIS COLON RECTUM, V32, P384, DOI 10.1007/BF02563689
   Nyam D C, 1997, J Gastrointest Surg, V1, P274, DOI 10.1016/S1091-255X(97)80120-5
   Oncel M, 2003, DIS COLON RECTUM, V46, P187, DOI 10.1007/s10350-004-6523-3
   Poritz LS, 2005, DIS COLON RECTUM, V48, P1685, DOI 10.1007/S10350-005-0128-3
   Poritz LS, 2004, INT J COLORECTAL DIS, V19, P481, DOI 10.1007/s00384-004-0580-x
   POST S, 1991, ANN SURG, V213, P37, DOI 10.1097/00000658-199101000-00007
   Prudhomme M, 2003, DIS COLON RECTUM, V46, P20, DOI 10.1007/s10350-004-6491-7
   Resegotti A, 2005, DIS COLON RECTUM, V48, P464, DOI 10.1007/s10350-004-0786-6
   Scarpa M, 2004, HEPATO-GASTROENTEROL, V51, P1053
   Schaden D, 2007, INT J COLORECTAL DIS, V22, P1453, DOI 10.1007/s00384-007-0337-4
   Schaffzin DM, 2004, DIS COLON RECTUM, V47, P1745, DOI 10.1007/s10350-004-0633-9
   Selvasekar CR, 2007, J AM COLL SURGEONS, V204, P956, DOI 10.1016/j.jamcollsurg.2006.12.044
   Shen B, 2004, AM J GASTROENTEROL, V99, P1527, DOI 10.1111/j.1572-0241.2004.30518.x
   Simillis C, 2007, DIS COLON RECTUM, V50, P1674, DOI 10.1007/s10350-007-9011-8
   Soop M, 2009, SURG ENDOSC, V23, P1876, DOI 10.1007/s00464-008-0308-z
   Stein RB, 2000, DRUG SAFETY, V23, P429, DOI 10.2165/00002018-200023050-00006
   Subramanian V, 2006, BRIT J SURG, V93, P793, DOI 10.1002/bjs.5375
   Subramanian V, 2008, AM J GASTROENTEROL, V103, P2373, DOI 10.1111/j.1572-0241.2008.01942.x
   Sugerman HJ, 2000, ANN SURG, V232, P530, DOI 10.1097/00000658-200010000-00008
   Taner T, 2009, INFLAMM BOWEL DIS, V15, P1208, DOI 10.1002/ibd.20882
   Tilney HS, 2006, SURG ENDOSC, V20, P1036, DOI 10.1007/s00464-005-0500-3
   Trickett JP, 2005, COLORECTAL DIS, V7, P519, DOI 10.1111/j.1463-1318.2005.00875.x
   Waljee A, 2006, GUT, V55, P1575, DOI 10.1136/gut.2005.090316
   Weston-Petrides GK, 2008, ARCH SURG-CHICAGO, V143, P406, DOI 10.1001/archsurg.143.4.406
   Wu JS, 1997, SURGERY, V122, P682, DOI 10.1016/S0039-6060(97)90074-X
   Yamamoto T, 1999, DIS COLON RECTUM, V42, P96, DOI 10.1007/BF02235190
   Yamamoto T, 2000, DIS COLON RECTUM, V43, P1141, DOI 10.1007/BF02236563
   Yamamoto T, 2007, DIS COLON RECTUM, V50, P1968, DOI 10.1007/s10350-007-0279-5
   Yousaf M, 2004, DIS COLON RECTUM, V47, P1403, DOI 10.1007/s10350-004-0576-1
NR 88
TC 30
Z9 33
U1 0
U2 7
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1078-0998
EI 1536-4844
J9 INFLAMM BOWEL DIS
JI Inflamm. Bowel Dis.
PD JUL
PY 2011
VL 17
IS 7
BP 1610
EP 1619
DI 10.1002/ibd.21504
PG 10
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA 787ZM
UT WOS:000292415200018
PM 21674718
DA 2026-07-24
ER

PT J
AU Skoracki, RJ
   Chang, DW
AF Skoracki, Roman J.
   Chang, David W.
TI Reconstruction of the chestwall and thorax
SO JOURNAL OF SURGICAL ONCOLOGY
LA English
DT Article
DE chestwall reconstruction
ID VACUUM-ASSISTED CLOSURE; LATISSIMUS-DORSI MUSCLE; MAJOR MYOCUTANEOUS
   FLAP; STERNAL WOUND-INFECTION; RECURRENT BREAST-CANCER; WALL
   RECONSTRUCTION; DONOR SITE; POSTSTERNOTOMY MEDIASTINITIS;
   MUSCULOCUTANEOUS FLAP; CONSECUTIVE PATIENTS
AB Chest wall reconstructions can be complex and challenging procedures and may require a multidisciplinary approach. The most common indications for chest wall reconstruction are the repair of defects due to tumor ablation, infection, radiation necrosis, congenital deformities, and trauma. Flap reconstruction by plastic surgery is often required when skin is removed as part of the chest wall resection or when radiation therapy is given pre- or post-operatively. Tissue flaps may be needed to provide vascularized tissue over alloplastic materials used to stabilize the chest wall, to cover vital structures of the chest cavity, to fill dead space, and to improve cosmesis.
C1 Univ Texas, MD Anderson Canc Ctr, Dept Plast Surg, Houston, TX 77230 USA.
C3 University of Texas System; UTMD Anderson Cancer Center
RP Chang, DW (通讯作者)，Univ Texas, MD Anderson Canc Ctr, Dept Plast Surg, PO 301402,Unit 443, Houston, TX 77230 USA.
EM dchang@mdanderson.org
CR Acarturk TO, 2004, ANN PLAS SURG, V53, P210, DOI 10.1097/01.sap.0000116285.98328.f7
   Adams WP, 2004, ANN PLAS SURG, V53, P6, DOI 10.1097/01.sap.0000106430.56501.b5
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   ARNOLD PG, 1986, PLAST RECONSTR SURG, V77, P605, DOI 10.1097/00006534-198604000-00016
   Arnold PG, 1996, PLAST RECONSTR SURG, V98, P804, DOI 10.1097/00006534-199610000-00008
   ARNOLD PG, 1994, PLAST RECONSTR SURG, V93, P324, DOI 10.1097/00006534-199402000-00015
   Arnold R. W., 1983, Pedogenesis and Soil Taxonomy. 1. Concepts and interactions, P1
   Baker AB, 2000, MICROVASC RES, V60, P177, DOI 10.1006/mvre.2000.2252
   BAROUDI R, 1978, PLAST RECONSTR SURG, V61, P547, DOI 10.1097/00006534-197804000-00008
   BAROUDI R, 1998, GRAGGS ENCY FLAPS, P1387
   Blondeel PN, 1997, BRIT J PLAST SURG, V50, P322, DOI 10.1016/S0007-1226(97)90540-3
   Bogossian N, 1996, PLAST RECONSTR SURG, V97, P97, DOI 10.1097/00006534-199601000-00016
   BOYD JB, 1984, PLAST RECONSTR SURG, V73, P1, DOI 10.1097/00006534-198401000-00001
   Castelli ML, 2001, EUR ARCH OTO-RHINO-L, V258, P542, DOI 10.1007/s004050100389
   Chen CS, 1997, SCIENCE, V276, P1425, DOI 10.1126/science.276.5317.1425
   CORMACK GC, 1994, ARTERIAL ANATOMY SKI, P85
   DAS SK, 1976, BRIT J PLAST SURG, V29, P170, DOI 10.1016/0007-1226(76)90045-X
   Delay E, 1998, PLAST RECONSTR SURG, V102, P1461, DOI 10.1097/00006534-199810000-00020
   Deo SVS, 2003, J SURG ONCOL, V83, P31, DOI 10.1002/jso.10236
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   FISHER J, 1983, PLAST RECONSTR SURG, V72, P502, DOI 10.1097/00006534-198310000-00015
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   FRAULIN FOG, 1995, ANN PLAS SURG, V35, P349, DOI 10.1097/00000637-199510000-00003
   Germann G, 1999, PLAST RECONSTR SURG, V103, P1386, DOI 10.1097/00006534-199904050-00007
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
   Hallock GG, 1997, J RECONSTR MICROSURG, V13, P47, DOI 10.1055/s-2008-1063940
   Harlan JW, 2002, PLAST RECONSTR SURG, V109, P710, DOI 10.1097/00006534-200202000-00045
   HARTRAMPF CR, 1982, PLAST RECONSTR SURG, V69, P216, DOI 10.1097/00006534-198202000-00006
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   HIDALGO DA, 1993, ANN PLAS SURG, V30, P375, DOI 10.1097/00000637-199304000-00017
   Horch RE, 2000, HEAD NECK-J SCI SPEC, V22, P513, DOI 10.1002/1097-0347(200008)22:5<513::AID-HED12>3.3.CO;2-E
   Korff T, 1999, J CELL SCI, V112, P3249
   Koshima I, 2001, ACTA MED OKAYAMA, V55, P329
   KOSHIMA I, 1993, PLAST RECONSTR SURG, V92, P411, DOI 10.1097/00006534-199309000-00004
   KROLL SS, 1992, AM J SURG, V164, P615, DOI 10.1016/S0002-9610(05)80719-6
   KROLL SS, 1995, PLAST RECONSTR SURG, V96, P616, DOI 10.1097/00006534-199509000-00013
   KROLL SS, 1993, ANN PLAS SURG, V31, P303, DOI 10.1097/00000637-199310000-00003
   LEE AB, 1976, SURGERY, V80, P433
   López-Monjardin H, 1998, PLAST RECONSTR SURG, V101, P1481, DOI 10.1097/00006534-199805000-00008
   Mansour KA, 2002, ANN THORAC SURG, V73, P1720, DOI 10.1016/S0003-4975(02)03527-0
   Mardini S, 2004, J RECONSTR MICROSURG, V20, P599, DOI 10.1055/s-2004-861517
   MARSHALL DR, 1981, BRIT J PLAST SURG, V34, P280, DOI 10.1016/0007-1226(81)90009-6
   Mathes SJ, 1997, RECONSTRUCTIVE SURG, P565
   MATHISEN DJ, 1988, J THORAC CARDIOV SUR, V95, P677
   McCarthy C, 2005, ANN PLAS SURG, V54, P361, DOI 10.1097/01.sap.0000151465.10356.dd
   MCCORMACK PM, 1989, SURG CLIN N AM, V69, P965
   Mehta S, 1996, PLAST RECONSTR SURG, V98, P31, DOI 10.1097/00006534-199607000-00006
   Menke H, 2001, ANN PLAS SURG, V47, P107, DOI 10.1097/00000637-200108000-00001
   Milano CA, 1999, ANN THORAC SURG, V67, P377, DOI 10.1016/S0003-4975(99)00022-3
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Moschella F, 1999, PLAST RECONSTR SURG, V103, P1378, DOI 10.1097/00006534-199904050-00006
   Motamed S, 2003, BURNS, V29, P842, DOI 10.1016/j.burns.2003.06.001
   NAHAI F, 1982, PLAST RECONSTR SURG, V70, P471, DOI 10.1097/00006534-198210000-00010
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   PALETTA CE, 1993, PLAST RECONSTR SURG, V92, P234, DOI 10.1097/00006534-199308000-00006
   Quinn TP, 2002, AM J PHYSIOL-LUNG C, V282, pL897, DOI 10.1152/ajplung.00044.2001
   ROWSELL AR, 1986, BRIT J PLAST SURG, V39, P206, DOI 10.1016/0007-1226(86)90083-4
   Saaristo A, 2002, FASEB J, V16, P1041, DOI 10.1096/fj.01-1042com
   SALMON RJ, 1988, BRIT J PLAST SURG, V41, P41, DOI 10.1016/0007-1226(88)90143-9
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Serafin D., 1996, Atlas of microsurgical composite tissue transplantation
   SLAVIN SA, 1994, PLAST RECONSTR SURG, V93, P811, DOI 10.1097/00006534-199404000-00024
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Takei T, 1997, J CELL PHYSIOL, V173, P64, DOI 10.1002/(SICI)1097-4652(199710)173:1<64::AID-JCP8>3.0.CO;2-H
   Tanzini I, 1906, GAZZ MED ITAL, V57, P141
   Titley OG, 1997, BRIT J PLAST SURG, V50, P106, DOI 10.1016/S0007-1226(97)91321-7
   Weinrach JC, 2004, ANN PLAS SURG, V53, P12, DOI 10.1097/01.sap.0000112286.30212.12
   WEINZWEIG N, 1995, ANN PLAS SURG, V34, P471, DOI 10.1097/00000637-199505000-00004
   WOODS JE, 1998, GRAGGS ENCY FLAPS, P1383
   Wu WC, 1997, BRIT J PLAST SURG, V50, P73, DOI 10.1016/S0007-1226(97)91317-5
   Zheng W, 2001, AM J PHYSIOL-HEART C, V280, pH909, DOI 10.1152/ajpheart.2001.280.2.H909
NR 72
TC 64
Z9 80
U1 0
U2 3
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0022-4790
EI 1096-9098
J9 J SURG ONCOL
JI J. Surg. Oncol.
PD NOV 1
PY 2006
VL 94
IS 6
BP 455
EP 465
DI 10.1002/jso.20482
PG 11
WC Oncology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Surgery
GA 102LO
UT WOS:000241812800003
PM 17061266
DA 2026-07-24
ER

PT J
AU Galetta, MS
   Kepler, CK
   Divi, SN
   Russo, GS
   Segar, AH
   Boody, BS
   Bronson, WH
   Rihn, JA
   Goyal, DKC
   Fang, TL
   Schroeder, GD
   Vaccaro, AR
AF Galetta, Matthew S.
   Kepler, Christopher K.
   Divi, Srikanth N.
   Russo, Glenn S.
   Segar, Anand H.
   Boody, Barrett S.
   Bronson, Wesley H.
   Rihn, Jeffrey A.
   Goyal, Dhruv K. C.
   Fang, Taolin
   Schroeder, Gregory D.
   Vaccaro, Alexander R.
TI Consensus on Wound Care of SSI in Spine Surgery
SO CLINICAL SPINE SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; SURGICAL SITE INFECTION; RISK-FACTORS; DURAL
   TEAR; THERAPY; IRRIGATION; MANAGEMENT; EFFICACY; PREVENTION; HERNIATION
AB In July of 2018, the Second International Consensus Meeting on Musculoskeletal Infection convened in Philadelphia, PA to discuss issues regarding infection in orthopedic patients and to provide consensus recommendations on these issues to practicing orthopedic surgeons. During this meeting, attending delegates divided into subspecialty groups to discuss topics specifics to their respective fields, which included the spine. At the spine subspecialty group meeting, delegates discussed and voted upon the recommendations for 63 questions regarding the prevention, diagnosis, and treatment of infection in spinal surgery. Of the 63 questions, 7 focused on wound care, for which this article provides the recommendations, voting results, and rationales.
C1 [Galetta, Matthew S.; Kepler, Christopher K.; Divi, Srikanth N.; Russo, Glenn S.; Segar, Anand H.; Boody, Barrett S.; Bronson, Wesley H.; Rihn, Jeffrey A.; Goyal, Dhruv K. C.; Fang, Taolin; Schroeder, Gregory D.; Vaccaro, Alexander R.] Rothman Orthopaed Inst, Dept Orthopaed, 925 Chestnut St,5th Floor, Philadelphia, PA 19107 USA.
C3 Rothman Institute
RP Galetta, MS (通讯作者)，Rothman Orthopaed Inst, Dept Orthopaed, 925 Chestnut St,5th Floor, Philadelphia, PA 19107 USA.
EM mgaletta@sas.upenn.edu
OI Divi, Srikanth/0000-0002-5776-2044; Goyal, Dhruv/0000-0002-5789-5410;
   Fang, Taolin/0000-0002-0468-066X
FU AO Spine; Medtronic
FX Dr. Schroeder has received funds to travel from AO Spine and Medtronic.
   Dr. Vaccaro has consulted or has done independent contracting for DePuy,
   Medtronic, Stryker Spine, Globus, Stout Medical, Gerson Lehrman Group,
   Guidepoint Global, Medacorp, Innovative Surgical Design, Orthobullets,
   Ellipse, and Vertex. He has also served on the scientific advisory
   board/board of directors/committees for Flagship Surgical, AO Spine,
   Innovative Surgical Design, and Association of Collaborative Spine
   Research. Dr. Vaccaro has received royalty payments from Medtronic,
   Stryker Spine, Globus, Aesculap, Thieme, Jaypee, Elsevier, and Taylor
   Francis/Hodder and Stoughton. He has stock/stock option ownership
   interests in Replication Medica, Globus, Paradigm Spine, Stout Medical,
   Progressive Spinal Technologies, Advanced Spinal Intellectual
   Properties, Spine Medica, Computational Biodynamics, Spinology, In Vivo,
   Flagship Surgical, Cytonics, Bonovo Orthopaedics, Electrocore, Gamma
   Spine, Location Based Intelligence, FlowPharma, R.S.I., Rothman
   Institute and Related Properties, Innovative Surgical Design, and Avaz
   Surgical. He has also served as deputy editor/editor of Spine. In
   addition, Dr. Vaccaro has also provided expert testimony. The remaining
   authors declare no conflict of interest.
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   Ahn DK, 2016, CLIN SPINE SURG, V29, P34, DOI 10.1097/BSD.0000000000000068
   Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe276, DOI [10.1016/s1473-3099(16)30402-9, 10.1016/s1473-3099(16)30398-x, 10.1016/S1473-3099(16)30398-X]
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Barendse-Hofmann M G, 2009, J Wound Care, V18, P79
   CALDERON W, 1986, PLAST RECONSTR SURG, V77, P785, DOI 10.1097/00006534-198605000-00016
   Calderone RR, 1996, ORTHOP CLIN N AM, V27, P171
   Canavese F, 2010, INDIAN J ORTHOP, V44, P177, DOI 10.4103/0019-5413.62067
   Chang FY, 2006, EUR SPINE J, V15, P1005, DOI 10.1007/s00586-005-0975-6
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Cheng MT, 2005, SPINE, V30, P1689, DOI 10.1097/01.brs.0000171907.60775.85
   Chieng LO, 2015, NEUROSURG FOCUS, V39, DOI 10.3171/2015.7.FOCUS15245
   Croft LD, 2015, SPINE, V40, pE112, DOI 10.1097/BRS.0000000000000693
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   DeFranzo AJ, 1999, PLAST RECONSTR SURG, V104, P2145, DOI 10.1097/00006534-199912000-00031
   Dessy LA, 2015, INT WOUND J, V12, P132, DOI 10.1111/iwj.12062
   Dumanian GA, 2003, SPINE, V28, P1203, DOI 10.1097/00007632-200306010-00022
   Edwards JR, 2009, AM J INFECT CONTROL, V37, P783, DOI 10.1016/j.ajic.2009.10.001
   ESHIMA I, 1990, PLAST RECONSTR SURG, V86, P541, DOI 10.1097/00006534-199009000-00026
   Gestring M, 2018, NEGATIVE PRESSURE WO
   Glaser DA, 2012, WOUNDS, V24, P308
   Grahovac G, 2011, SPINE, V36, pE1761, DOI 10.1097/BRS.0b013e31821cb9fd
   Jones GA, 2007, J NEUROSURG-SPINE, V6, P407, DOI 10.3171/spi.2007.6.5.407
   Jung YY, 2010, J KOREAN NEUROSURG S, V47, P316, DOI 10.3340/jkns.2010.47.4.316
   Kanakaris NK, 2007, INJURY, V38, pS9, DOI 10.1016/j.injury.2007.10.029
   Kim JH, 2015, CLIN ORTHOP SURG, V7, P337, DOI 10.4055/cios.2015.7.3.337
   Koutsoumbelis S, 2011, J BONE JOINT SURG AM, V93A, P1627, DOI 10.2106/JBJS.J.00039
   Meara JG, 1999, ANN PLAS SURG, V42, P589, DOI 10.1097/00000637-199906000-00002
   Mehbod AA, 2005, J SPINAL DISORD TECH, V18, P14, DOI 10.1097/01.bsd.0000133493.32503.d3
   Mitra A, 2004, PLAST RECONSTR SURG, V113, P206, DOI 10.1097/01.PRS.0000097440.15013.5C
   Mohammed-Ali RI, 2012, BRIT J ORAL MAX SURG, V50, P88, DOI 10.1016/j.bjoms.2010.10.014
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   MURPHY RC, 1986, J SURG RES, V41, P75, DOI 10.1016/0022-4804(86)90011-9
   Myung KS, 2014, J PEDIATR ORTHOPED, V34, P29, DOI 10.1097/BPO.0b013e31829b2d75
   Nordmeyer M, 2016, INT WOUND J, V13, P1176, DOI 10.1111/iwj.12436
   Olsen MA, 2003, J NEUROSURG, V98, P149, DOI 10.3171/spi.2003.98.2.0149
   Ousey KJ, 2013, SPINE J, V13, P1393, DOI 10.1016/j.spinee.2013.06.040
   Parvizi J, 2013, BONE JOINT J, V95B, P1450, DOI 10.1302/0301-620X.95B11.33135
   Ploumis A, 2008, J SPINAL DISORD TECH, V21, P320, DOI 10.1097/BSD.0b013e318141f99d
   Prince N, 2015, ANN PLAS SURG, V74, pS218, DOI 10.1097/SAP.0000000000000374
   RAWLINGS CE, 1983, NEUROSURGERY, V13, P371, DOI 10.1227/00006123-198310000-00004
   Rijal L, 2011, EUR J ORTHOP SURG TR, V21, P449, DOI 10.1007/s00590-010-0729-y
   Sebastian A, 2016, SPINE J, V16, P504, DOI 10.1016/j.spinee.2015.12.009
   Sporns PB, 2016, ROFO-FORTSCHR RONTG, V188, P451, DOI 10.1055/s-0035-1567034
   Sporns PB, 2015, SPINE J, V15, pE13, DOI 10.1016/j.spinee.2015.04.025
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Tomov M, 2015, SPINE, V40, P491, DOI 10.1097/BRS.0000000000000789
   TURNBULL F, 1953, J NEUROSURG, V10, P469, DOI 10.3171/jns.1953.10.5.0469
   Watanabe M, 2010, J NEUROSURG-SPINE, V12, P540, DOI 10.3171/2009.11.SPINE09308
   Watt JP, 2017, GLOB SPINE J, V7, P756, DOI 10.1177/2192568217696694
   Webster J, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub2
   Zhu RS, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000005022
NR 53
TC 5
Z9 5
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 2380-0186
EI 2380-0194
J9 CLIN SPINE SURG
JI Clin. Spine Surg.
PD JUN
PY 2020
VL 33
IS 5
BP E206
EP E212
DI 10.1097/BSD.0000000000000853
PG 7
WC Clinical Neurology; Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Orthopedics
GA LV0KU
UT WOS:000538134000009
PM 31180993
DA 2026-07-24
ER

PT J
AU Rohrich, RJ
   Lowe, JB
   Hackney, FL
   Bowman, JL
   Hobar, PC
AF Rohrich, RJ
   Lowe, JB
   Hackney, FL
   Bowman, JL
   Hobar, PC
TI An algorithm for abdominal wall reconstruction
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID TENSOR FASCIAE LATAE; EXPANDED POLYTETRAFLUOROETHYLENE PATCH;
   VACUUM-ASSISTED CLOSURE; POLYPROPYLENE MESH; MYOCUTANEOUS FLAP;
   INCISIONAL HERNIA; CLINICAL-EXPERIENCE; VENTRAL HERNIA; WOUND CONTROL;
   MUSCLE FLAP
AB Acquired abdominal wall defects result from trauma, previous surgery, infection, and tumor resection. The correction of complex defects is a challenge to both plastic and reconstructive and general surgeons. The anatomy of the abdominal wall, as well as considerations in patient assessment and surgical planning, are discussed. A simple classification of abdominal wall defects based on size, depth, and location is provided. Publications regarding the various abdominal reconstruction techniques are reviewed and summarized to familiarize the reader with the treatment options for each particular defect. Finally, an algorithm is presented to guide the surgeon in selecting the optimal reconstructive technique.
C1 Univ Texas, SW Med Ctr, Dept Plast & Reconstruct Surg, Dallas, TX 75235 USA.
C3 University of Texas System; University of Texas Dallas; University of
   Texas Southwestern Medical Center
RP Rohrich, RJ (通讯作者)，Univ Texas, SW Med Ctr, Dept Plast & Reconstruct Surg, 5323 Harry Hines Blvd,Suite E7-210, Dallas, TX 75235 USA.
EM rrohri@mednet.swmed.edu
RI rohrich, rod/AAJ-7504-2020
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   ARGENTA LC, 1985, CLIN PLAST SURG, V12, P159
   BARIE PS, 1995, AM J SURG, V170, P62, DOI 10.1016/S0002-9610(99)80254-2
   BAUER JJ, 1987, ANN SURG, V206, P765, DOI 10.1097/00000658-198712000-00013
   BLEICHRODT RP, 1993, SURG GYNECOL OBSTET, V176, P18
   BOSTWICK J, 1979, PLAST RECONSTR SURG, V63, P186, DOI 10.1097/00006534-197902000-00006
   BROWN DM, 1993, SURGERY, V114, P112
   BROWN GL, 1985, ANN SURG, V201, P705, DOI 10.1097/00000658-198506000-00006
   BURNETT C, 1995, CARBOMEDICS, V7, P1
   BYRD HS, 1989, PLAST RECONSTR SURG, V84, P347, DOI 10.1097/00006534-198908000-00026
   CAFFEE HH, 1983, PLAST RECONSTR SURG, V71, P348, DOI 10.1097/00006534-198303000-00010
   CAULFIELD WH, 1994, ANN PLAS SURG, V32, P377, DOI 10.1097/00000637-199404000-00010
   CHUNG KW, 1988, GROSS ANATOMY, P159
   Classen D, 1999, ANN PLAS SURG, V42, P137, DOI 10.1097/00000637-199902000-00005
   Cooper TM, 1999, PLAST RECONSTR SURG, V103, P918, DOI 10.1097/00006534-199903000-00022
   CORE GB, 1995, AESTHETIC RECONSTRUC, V2, P1327
   Corps B V, 1969, Br J Plast Surg, V22, P125, DOI 10.1016/S0007-1226(69)80053-6
   DeFranzo AJ, 1996, ANN PLAS SURG, V37, P18, DOI 10.1097/00000637-199607000-00003
   DIBBELL DG, 1991, PLAST RECONSTR SURG, V87, P60, DOI 10.1097/00006534-199101000-00011
   DiBello JN, 1996, PLAST RECONSTR SURG, V98, P464, DOI 10.1097/00006534-199609000-00016
   DIEBEL LN, 1992, J TRAUMA, V33, P279, DOI 10.1097/00005373-199208000-00019
   Disa JJ, 1998, PLAST RECONSTR SURG, V101, P979, DOI 10.1097/00006534-199804040-00014
   Dowden R V, 1980, Ann Plast Surg, V4, P396, DOI 10.1097/00000637-198005000-00007
   EARLE AS, 1975, PLAST RECONSTR SURG, V56, P447, DOI 10.1097/00006534-197510000-00018
   FABIAN TC, 1994, ANN SURG, V219, P643, DOI 10.1097/00000658-199406000-00007
   FAGNIEZ PL, 1985, ARCH SURG-CHICAGO, V120, P1351
   FRY DE, 1991, SURG CLIN N AM, V71, P1
   GER R, 1983, PLAST RECONSTR SURG, V72, P170, DOI 10.1097/00006534-198308000-00008
   Girotto JA, 1999, ANN PLAS SURG, V42, P385, DOI 10.1097/00000637-199904000-00007
   GOTTLIEB JR, 1990, PLAST RECONSTR SURG, V86, P281, DOI 10.1097/00006534-199008000-00013
   GOTTLIEB ME, 1986, PLAST RECONSTR SURG, V78, P782, DOI 10.1097/00006534-198678060-00012
   GRAVES G, 1980, CLIN BULL, V10, P144
   Gruen RL, 1998, AUST NZ J SURG, V68, P666, DOI 10.1111/j.1445-2197.1998.tb04841.x
   HADDAD CM, 1968, REV ASSOC MED BRAS, V14, P255
   HALLOCK GG, 1991, PLAST RECONSTR SURG, V88, P673, DOI 10.1097/00006534-199110000-00018
   HILL HL, 1978, PLAST RECONSTR SURG, V61, P517, DOI 10.1097/00006534-197804000-00004
   HOBAR PC, 1994, PLAST RECONSTR SURG, V94, P379, DOI 10.1097/00006534-199408000-00027
   HOUCK JP, 1989, SURG GYNECOL OBSTET, V169, P397
   HOUSTON GC, 1988, PLAST RECONSTR SURG, V81, P917, DOI 10.1097/00006534-198806000-00015
   HUGER WE, 1979, AM SURGEON, V45, P612
   HURWTIZ DJ, 1994, MASTERY PLASTIC RECO, V1
   Jacobsen WM, 1997, PLAST RECONSTR SURG, V100, P326, DOI 10.1097/00006534-199708000-00007
   KOSHIMA I, 1989, BRIT J PLAST SURG, V42, P645, DOI 10.1016/0007-1226(89)90075-1
   LARSON GM, 1984, SURG CLIN N AM, V64, P335
   LAW NW, 1991, SURGERY, V109, P652
   LOCKWOOD TE, 1991, PLAST RECONSTR SURG, V87, P1009, DOI 10.1097/00006534-199106000-00001
   LOWE JB, UNPUB ENDOSCOPIC ASS
   MARKMAN B, 1989, CLIN PLAST SURG, V16, P235
   MATHES SJ, 1977, BRIT J PLAST SURG, V30, P282, DOI 10.1016/0007-1226(77)90118-7
   Mathes SJ., 1997, Reconstructive surgery: principles, anatomy technique, V1st
   MATHES SJ, 1982, CLIN APPL MUSCLE MUS, P364
   MILLARD DR, 1969, PLAST RECONSTR SURG, V43, P569, DOI 10.1097/00006534-196906000-00002
   MILLER SH, 1990, CLIN PLAST SURG, V17, P503
   MORRIS JA, 1993, ANN SURG, V217, P576, DOI 10.1097/00000658-199305010-00019
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   MUDGE M, 1985, BRIT J SURG, V72, P70, DOI 10.1002/bjs.1800720127
   NAHAI F, 1979, PLAST RECONSTR SURG, V63, P788, DOI 10.1097/00006534-197963060-00004
   NAHAI F, 1976, AM SURGEON, V42, P691
   Netter F.H., 1989, Atlas of Human Anatomy, VFirst
   NIELSEN IM, 1985, SCAND J PLAST RECONS, V19, P53, DOI 10.3109/02844318509052865
   Ninkovic M, 1998, PLAST RECONSTR SURG, V101, P971, DOI 10.1097/00006534-199804040-00013
   OHTSUKA H, 1984, BRIT J PLAST SURG, V37, P327, DOI 10.1016/0007-1226(84)90075-4
   PADGETT EC, 1967, PLAST RECONSTR SURG, V39, P195, DOI 10.1097/00006534-196702000-00012
   Paletta CE, 1999, ANN PLAS SURG, V42, P259, DOI 10.1097/00000637-199903000-00006
   PARKASH S, 1983, BRIT J SURG, V70, P68, DOI 10.1002/bjs.1800700204
   POWANDA MC, 1981, SURG GYNECOL OBSTET, V153, P749
   RAMASASTRY SS, 1985, ANN PLAS SURG, V15, P57, DOI 10.1097/00000637-198507000-00007
   RAMIREZ OM, 1990, PLAST RECONSTR SURG, V86, P519, DOI 10.1097/00006534-199009000-00023
   READ RC, 1992, REOPERATIVE GEN SURG, P485
   RICHARDS PC, 1983, ANN SURG, V197, P238, DOI 10.1097/00000658-198302000-00018
   RICHMOND G, 1983, J AUTISM DEV DISORD, V13, P197, DOI 10.1007/BF01531819
   ROBINSON DW, 1975, PLAST RECONSTR SURG, V55, P41, DOI 10.1097/00006534-197501000-00007
   ROBINSON JB, 1996, SEL READ PLAST SURG, V8, P1
   ROBSON MC, 1990, CLIN PLAST SURG, V17, P485
   RUDOLPH R, 1973, SURG GYNECOL OBSTET, V136, P641
   SANTORA TA, 1993, SURG CLIN N AM, V73, P557
   Scarpa A., 1809, Sullernie Memorie Anatomico-Chirugiche
   Schwartz S I., 1994, Principles of Surgery, V6th
   SENSOZ O, 1990, ANN PLAS SURG, V25, P193
   SILBERMAN DA, 1985, ANN PLAS SURG, V15, P170, DOI 10.1097/00000637-198508000-00015
   SPEAR SL, 1992, PLAST RECONSTR SURG, V90, P608, DOI 10.1097/00006534-199210000-00009
   STERN HS, 1992, BRIT J PLAST SURG, V45, P270, DOI 10.1016/0007-1226(92)90050-8
   STOPPA RE, 1989, WORLD J SURG, V13, P545, DOI 10.1007/BF01658869
   TEMPLE WJ, 1975, ANN SURG, V182, P93, DOI 10.1097/00000658-197508000-00001
   TERASHI H, 1995, ANN PLAS SURG, V35, P320, DOI 10.1097/00000637-199509000-00018
   THOMAS WO, 1993, PLAST RECONSTR SURG, V91, P1080, DOI 10.1097/00006534-199305000-00017
   VENUGOPALAN S, 1980, BRIT J PLAST SURG, V33, P43, DOI 10.1016/0007-1226(80)90051-X
   VOYLES CR, 1981, ANN SURG, V194, P219, DOI 10.1097/00000658-198108000-00017
   Williams JK, 1998, PLAST RECONSTR SURG, V101, P713, DOI 10.1097/00006534-199803000-00020
   WISSING J, 1987, BRIT J SURG, V74, P738, DOI 10.1002/bjs.1800740831
   WOOD RJ, 1988, AM SURGEON, V54, P648
NR 91
TC 148
Z9 173
U1 0
U2 17
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JAN
PY 2000
VL 105
IS 1
BP 202
EP 216
DI 10.1097/00006534-200001000-00036
PG 15
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 270AR
UT WOS:000084513700036
PM 10626993
DA 2026-07-24
ER

PT J
AU Kwaadu, KY
AF Kwaadu, Kwasi Y.
TI Charcot Reconstruction Understanding and Treating the Deformed Charcot
   Neuropathic Arthropathic Foot
SO CLINICS IN PODIATRIC MEDICINE AND SURGERY
LA English
DT Review
DE Amputation; Charcot neuroarthropathy; Charcot neuropathic arthropathy;
   Diabetes; Diabetic foot deformity; Equinus; Superconstructs
ID VACUUM-ASSISTED CLOSURE; PRESSURE WOUND THERAPY; DIABETIC FOOT;
   NEUROARTHROPATHY; RISK; FUSION; SCREW; EQUINUS; ANKLE
AB With worsening diet and increasing prevalence of diabetes, patient encounters with Charcot neuropathic arthropathy (CNA) are expected to increase. Without intervention, the pathology progresses with further subluxation/dislocation and fracture, placing soft tissues at risk of preulceration or formal ulceration, infection, and potentially major amputation. The need to avoid amputation is of paramount importance. Although a formal single eradicating tool for CNA is lacking, there is capacity to intervene in ways that may curtail the pace of destruction. This article reviews understanding of the disease process and provides guidance to surgical reconstruction of the deformity.
C1 [Kwaadu, Kwasi Y.] Temple Univ, Sch Podiatr Med, Dept Surg, 148 North 8th St, Philadelphia, PA 19107 USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple
   University
RP Kwaadu, KY (通讯作者)，Temple Univ, Sch Podiatr Med, Dept Surg, 148 North 8th St, Philadelphia, PA 19107 USA.
EM kkwaadu@gmail.com
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Assal M, 2009, J BONE JOINT SURG AM, V91A, P812, DOI 10.2106/JBJS.G.01396
   Botek G, 2019, CLIN PODIATR MED SUR, V36, P663, DOI 10.1016/j.cpm.2019.07.002
   Brodsky JW, 2007, SURG FOOT ANKLE, P1281
   Burns Patrick R, 2008, Clin Podiatr Med Surg, V25, P95, DOI 10.1016/j.cpm.2007.10.008
   Busch-Westbroek TE, 2018, DIABETES CARE, V41, pE21, DOI 10.2337/dc17-1517
   CHANG BB, 1993, CLIN ORTHOP RELAT R, P27
   Coughlin M.J., 2007, SURG FOOT ANKLE, P923
   DeCarbo WT, 2010, J FOOT ANKLE SURG, V49, P299, DOI 10.1053/j.jfas.2010.01.002
   Elmarsafi T, 2019, J FOOT ANKLE SURG, V58, P295, DOI 10.1053/j.jfas.2018.08.059
   Frykberg Robert G, 2006, J Foot Ankle Surg, V45, pS1
   Frykberg RG, 2012, J AM PODIAT MED ASSN, V102, P84, DOI 10.7547/1020084
   Gomoll AH, 2006, J ORTHOP TRAUMA, V20, P705, DOI 10.1097/01.bot.0000211159.98239.d2
   Greenhagen RM, 2012, CLIN PODIATR MED SUR, V29, P413, DOI 10.1016/j.cpm.2012.04.005
   Hastings MK, 2013, J BONE JOINT SURG AM, V95A, P1206, DOI 10.2106/JBJS.L.00250
   Jeffcoate WJ, 2015, DIABETIC MED, V32, P760, DOI 10.1111/dme.12754
   Jeffcoate William, 2008, Clin Podiatr Med Surg, V25, P29, DOI 10.1016/j.cpm.2007.10.003
   Kann JN, 1999, FOOT ANKLE INT, V20, P33
   Labovitz JM, 2018, J FOOT ANKLE SURG, V57, P952, DOI 10.1053/j.jfas.2018.03.036
   Lamm BM, 2012, J FOOT ANKLE SURG, V51, P531, DOI 10.1053/j.jfas.2012.04.021
   Mabilleau G, 2008, DIABETOLOGIA, V51, P1035, DOI 10.1007/s00125-008-0992-1
   Marks RM, 1998, FOOT ANKLE INT, V19, P507, DOI 10.1177/107110079801900801
   Miller AN, 2011, J BONE JOINT SURG AM, V93A, P1116, DOI [10.2106/JBJS.J.00693, 10.2106/JBJSJ.00693]
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Pakarinen Toni-Karri, 2009, Foot Ankle Surg, V15, P187, DOI 10.1016/j.fas.2009.02.005
   Petrisor Brad, 2005, Foot Ankle Clin, V10, P609, DOI 10.1016/j.fcl.2005.06.003
   Pinzur MS, 2018, FOOT ANKLE INT, V39, P265, DOI 10.1177/1071100717742371
   Reddy GK, 2004, EXP DIABESITY RES, V5, P143, DOI 10.1080/15438600490277860
   Rettedal D, 2018, J FOOT ANKLE SURG, V57, P451, DOI 10.1053/j.jfas.2017.10.021
   Richard JL, 2012, DIABETOLOGIA, V55, P1258, DOI 10.1007/s00125-012-2507-3
   SAMMARCO GJ, 1991, FOOT DIABETES, P153
   Sammarco VJ, 2009, FOOT ANKLE CLIN, V14, P393, DOI 10.1016/j.fcl.2009.04.004
   Saxena Amol, 2005, J Foot Ankle Surg, V44, P450, DOI 10.1053/j.jfas.2005.07.018
   Schneekloth BJ, 2016, J FOOT ANKLE SURG, V55, P586, DOI 10.1053/j.jfas.2015.12.001
   Simon SR, 2000, J BONE JOINT SURG AM, V82A, P939, DOI 10.2106/00004623-200007000-00005
   Sohn MW, 2009, DIABETES CARE, V32, P816, DOI 10.2337/dc08-1695
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Strauss E, 1998, CLIN ORTHOP RELAT R, P132
   Uccioli L, 2010, DIABETES CARE, V33, P350, DOI 10.2337/dc09-1141
   Varma AK, 2013, J FOOT ANKLE SURG, V52, P740, DOI 10.1053/j.jfas.2013.07.001
   Wukich DK, 2017, FOOT ANKLE INT, V38, P140, DOI 10.1177/1071100716673985
   Wukich DK, 2014, FOOT ANKLE INT, V35, P1108, DOI 10.1177/1071100714547218
   Wukich DK, 2014, J BONE JOINT SURG AM, V96A, P832, DOI 10.2106/JBJS.L.01302
   Wukich DK, 2009, J DIABETES COMPLICAT, V23, P409, DOI 10.1016/j.jdiacomp.2008.09.004
NR 45
TC 13
Z9 14
U1 0
U2 4
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0891-8422
EI 1558-2302
J9 CLIN PODIATR MED SUR
JI Clin. Podiatr. Med. Surg.
PD APR
PY 2020
VL 37
IS 2
BP 247
EP +
DI 10.1016/j.cpm.2019.12.002
PG 16
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA LG6HN
UT WOS:000528199800005
PM 32146981
DA 2026-07-24
ER

PT J
AU Schlueer, AB
   Schwieger-Briel, A
   Theiler, M
   Neuhaus, K
   Schiestl, C
   Weibel, L
AF Schlueer, Anna-Barbara
   Schwieger-Briel, Agnes
   Theiler, Martin
   Neuhaus, Kathrin
   Schiestl, Clemens
   Weibel, Lisa
TI Negative pressure wound treatment in a neonate with epidermolysis
   bullosa simplex severe generalized: A case report
SO PEDIATRIC DERMATOLOGY
LA English
DT Article
DE epidermolysis bullosa; negative pressure wound treatment; vacuum
   assisted closure
ID THERAPY; MANAGEMENT
AB Negative pressure wound treatment (NPWT) is very useful for the treatment of chronic or deep wounds and in the setting of skin grafting. Due to the need for adhesive dressings, this treatment is rarely attempted in patients with skin fragility secondary to hereditary epidermolysis bullosa (EB). We present a neonate with EB simplex, severe generalized in a critical clinical state where NPWT was successfully applied and describe the measures taken to avoid any further skin damage. This case is of clinical importance to physicians and health care staff treating patients with this rare disease where additional therapeutic measures for the treatment of chronic wounds are scarce.
C1 [Schlueer, Anna-Barbara; Schwieger-Briel, Agnes; Theiler, Martin; Weibel, Lisa] Univ Childrens Hosp Zurich, Dept Pediat Dermatol, Pediat Skin Ctr, Zurich, Switzerland.
   [Schlueer, Anna-Barbara] Univ Childrens Hosp Zurich, Dept Nursing Sci, Zurich, Switzerland.
   [Schlueer, Anna-Barbara; Schwieger-Briel, Agnes; Theiler, Martin; Neuhaus, Kathrin; Schiestl, Clemens; Weibel, Lisa] Univ Childrens Hosp Zurich, Childrens Res Ctr, Zurich, Switzerland.
   [Neuhaus, Kathrin; Schiestl, Clemens] Univ Childrens Hosp Zurich, Pediat Skin Ctr, Dept Plast & Reconstruct Surg, Zurich, Switzerland.
C3 University Children's Hospital Zurich; University Children's Hospital
   Zurich; University Children's Hospital Zurich; University Children's
   Hospital Zurich
RP Schlueer, AB (通讯作者)，Univ Childrens Hosp, Dept Pediat Dermatol, Pediat Skin Ctr, Steinwiesstr 75, CH-8032 Zurich, Switzerland.
EM Agnes.Schwieger@kispi.uzh.ch
OI Schwieger-Briel, Agnes/0000-0001-7679-3981; Theiler,
   Martin/0000-0001-7160-3958; Weibel, Lisa/0000-0002-8696-8164; Neuhaus,
   Kathrin/0000-0003-2438-1779; Schlüer, Anna-Barbara/0000-0003-1046-3650
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
   Bafaraj MG, 2014, INT WOUND J, V11, P274, DOI 10.1111/j.1742-481X.2012.01087.x
   Baharestani M, 2009, INT WOUND J, V6, P1, DOI 10.1111/j.1742-481X.2009.00607.x
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Iheozor-Ejiofor Z, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD012522.pub2
   Kantak NA, 2016, BURNS, V42, P1623, DOI 10.1016/j.burns.2016.06.011
   Lalezari S, 2017, INT WOUND J, V14, P649, DOI 10.1111/iwj.12658
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Pedrazzi NE, 2021, ADV WOUND CARE, V10, P270, DOI 10.1089/wound.2019.1089
   Rentea RM, 2013, J SURG RES, V184, P658, DOI 10.1016/j.jss.2013.05.056
   Sherman G, 2020, PEDIATR CRIT CARE ME, V21, P150, DOI 10.1097/PCC.0000000000002131
   Upton D, 2015, INT WOUND J, V12, P100, DOI 10.1111/iwj.12059
   Yin YC, 2018, INT J SURG, V50, P43, DOI 10.1016/j.ijsu.2017.12.020
NR 14
TC 1
Z9 2
U1 0
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0736-8046
EI 1525-1470
J9 PEDIATR DERMATOL
JI Pediatr. Dermatol.
PD NOV
PY 2020
VL 37
IS 6
BP 1218
EP 1220
DI 10.1111/pde.14335
EA SEP 2020
PG 3
WC Dermatology; Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Pediatrics
GA PB7HP
UT WOS:000566267300001
PM 32892402
DA 2026-07-24
ER

PT J
AU Marchaland, JP
   Bey, E
   Paranque, A
   Ollat, D
   Boddaert, G
   Versier, G
AF Marchaland, J. -P.
   Bey, E.
   Paranque, A.
   Ollat, D.
   Boddaert, G.
   Versier, G.
TI First treatment of distal loss of tissue on lower limbs. About 15 cases
SO ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE
LA French
DT Article
DE loss of tissue; foot; ankle; trauma; wound heating; reconstructive
   surgery; pediled faciocutaneous flaps
ID FREE FLAPS; RECONSTRUCTION; MANAGEMENT; FRACTURES; INJURIES
AB Distal extremity of Lower limb sustains the complications of loss of tissue: problem of coverage (cutaneous and tendon necrosis, osteoarticutar infection. The whole point of the surgery is to fight against the infection by repeated debridments, against the deformations or their correction by early osteosynthesis (pins and external fixation). The coverage is very important in this treatment: either with Vacuum-Assisted Closure (VAC (R)) and skin graft or fasciocutaneous flap. In spite of this management, the after-effects are important although the conservative treatment is the determining factor of satisfaction. (C) 2007 Elsevier Masson SAS. Tous droits reserves.
C1 [Marchaland, J. -P.; Ollat, D.; Boddaert, G.; Versier, G.] HIA Begin, Serv Chirurg Orthoped & Traumatol, F-94160 St Mande, France.
   [Bey, E.] HIA Percy, Serv Chirurg Plast & Reconstructrice, F-92140 Clamart, France.
   [Paranque, A.] HIA Begin, Serv Chirurg Maxillofaciale & Stomatol, F-94160 St Mande, France.
RP Marchaland, JP (通讯作者)，HIA Begin, Serv Chirurg Orthoped & Traumatol, 69 Ave Paris, F-94160 St Mande, France.
EM jpmarchaland@voila.fr
RI BODDAERT, Guillaume/MKF-0045-2025
OI BODDAERT, Guillaume/0000-0002-0536-3850
CR Belfkira F, 2006, Ann Chir Plast Esthet, V51, P199, DOI 10.1016/j.anplas.2005.12.010
   BONNEVIALLE P, 2000, CAH ENS SOFC C ENS, P91
   BYRD HS, 1985, PLAST RECONSTR SURG, V76, P719, DOI 10.1097/00006534-198511000-00011
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   HIDALGO DA, 1986, PLAST RECONSTR SURG, V78, P627
   HIDALGO DA, 1987, LATISSIMUS DORSI FRE, P245
   Kenzora J E, 1981, Foot Ankle, V1, P348
   KHOURI RK, 1989, J TRAUMA, V29, P1086, DOI 10.1097/00005373-198908000-00005
   KIM SS, 1994, MICROSURGICAL RECONS, V2, P171
   Labler L., 2004, Eur J Trauma, V30, P305, DOI 10.1007/s00068-004-1389-6
   Le Nen D, 1996, Ann Chir Plast Esthet, V41, P127
   MASQUELET AC, 1999, ENCY MED CHIR PARIS
   Page JC, 2005, WOUNDS, p9S
   Pinsolle V, 2006, J PLAST RECONSTR AES, V59, P912, DOI 10.1016/j.bjps.2005.11.037
   Riccio M, 2005, MICROSURG, V25, P272, DOI 10.1002/micr.20132
   Seibert Franz Josef, 2003, Clin Podiatr Med Surg, V20, P159, DOI 10.1016/S0891-8422(02)00057-5
   Shilt JS, 2004, J PEDIATR ORTHOPED, V24, P482, DOI 10.1097/01241398-200409000-00006
   VERSIER G, 2005, EMC
NR 18
TC 6
Z9 6
U1 0
U2 1
PU ELSEVIER
PI BRIDGEWATER
PA 685 ROUTE 202-206, BRIDGEWATER, NJ 08807 USA
SN 0294-1260
J9 ANN CHIR PLAST ESTH
JI Ann. Chir. Plast. Esthet.
PD FEB
PY 2008
VL 53
IS 1
BP 14
EP 21
DI 10.1016/j.anplas.2007.04.005
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 322WP
UT WOS:000257406300003
PM 17961899
DA 2026-07-24
ER

PT J
AU D'Hondt, M
   D'Haeninck, A
   Dedrye, L
   Penninckx, F
   Aerts, R
AF D'Hondt, M.
   D'Haeninck, A.
   Dedrye, L.
   Penninckx, F.
   Aerts, R.
TI Can vacuum-assisted closure and instillation therapy
   (VAC-InstillA® therapy) play a role in the treatment of the
   infected open abdomen?
SO TECHNIQUES IN COLOPROCTOLOGY
LA English
DT Article
DE VAC-Instill; Infection; Open abdomen
ID WOUND CONTROL
AB Severe superimposed infection during open abdomen treatment with development of intra-abdominal sepsis is a challenging complication associated with high mortality rates. We report our experience with VAC-Instill(A (R)) therapy (KCI, San Antonio, USA) used for treatment of an infected open abdomen following pancreatic surgery. A literature search revealed no analogous case reports using VAC-Instill(A (R)) therapy for treatment of an infected laparostomy. The encouraging result of the case presented seems to indicate that VAC-Instill(A (R)) therapy could be used as adjunctive treatment in the management of the infected open abdomen when traditional therapy fails to control the infection.
C1 [D'Hondt, M.; D'Haeninck, A.; Dedrye, L.; Penninckx, F.; Aerts, R.] Univ Hosp Leuven, Dept Digest Surg, B-3000 Louvain, Belgium.
C3 KU Leuven; University Hospital Leuven
RP D'Hondt, M (通讯作者)，Kleine Leiestr 1, B-8500 Kortrijk, Belgium.
EM mathieudhondt2000@yahoo.com
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bryskier A, 2005, ANTIMICROBIAL AGENTS: ANTIBACTERIALS AND ANTIFUNGALS, pXXVII
   Gabriel A, 2008, INT WOUND J, V5, P399, DOI 10.1111/j.1742-481X.2007.00423.x
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   Martin RR, 1997, SURG CLIN N AM, V77, P929, DOI 10.1016/S0039-6109(05)70595-8
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Wolvos Tom, 2004, Ostomy Wound Manage, V50, P56
NR 7
TC 24
Z9 30
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1123-6337
J9 TECH COLOPROCTOL
JI Tech. Coloproctology
PD MAR
PY 2011
VL 15
IS 1
BP 75
EP 77
DI 10.1007/s10151-010-0662-4
PG 3
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 728CF
UT WOS:000287850900011
PM 21234637
DA 2026-07-24
ER

PT J
AU Bourrée, M
   Kozianka, J
AF Bourrée, M
   Kozianka, J
TI 6 years V-AC® in general surgery - Clinical data from 128 patients
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nurnberg, GERMANY
DE VAC (R) in general surgery; Fournier's gangrene; treatment of infection
AB Since the introduction of vacuum assisted closure therapy (V.A.C.(R)) at the Department of Surgery/St. Anna-Hospital Herne has taken place in 2000 there was a rapid increase of indications to use this therapy. We present data from 128 patients who were treated with this method from 2000-2005 for different kinds of diseases. We report the management of a 78-year-old male patient who developed a Fournier's gangrene after an acute appendicitis with retroperitoneal perforation and an enterocutaneus fistula of the cecum. Using V.A.C.(R) in surgery, a quick and safe treatment of infection and healing could be achieved.
C1 Privaten Univ Witten Herdecke, St Anna Hosp, Chirurg Klin, Ausbildungsklin, D-44649 Herne, Germany.
C3 Saint Anna Hospital
RP Bourrée, M (通讯作者)，Privaten Univ Witten Herdecke, St Anna Hosp, Chirurg Klin, Ausbildungsklin, Hosp Str 19, D-44649 Herne, Germany.
EM bourree@annahospital.de
CR AGENTA LC, 1997, ANN PLAST SURG, V38, P563
   BOURREE M, 2003, 35191 ACA, P35
   Fleischmann W, 1998, CHIRURG, V69, P222, DOI 10.1007/s001040050402
   Walgenbach KJ, 2000, Z FLUGWISS WELTRAUM, V13, P9
   Wild T, 2004, ZBL CHIR, V129, pS20, DOI 10.1055/s-2004-822651
NR 5
TC 3
Z9 3
U1 0
U2 1
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S100
EP S104
DI 10.1055/s-2006-921457
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 034DB
UT WOS:000236904100023
PM 16575656
DA 2026-07-24
ER

PT J
AU Friedrich, JB
   Katolik, LI
   Hanel, DP
AF Friedrich, Jeffrey B.
   Katolik, Leonid I.
   Hanel, Douglas P.
TI Reconstruction of Soft-tissue Injury Associated With Lower Extremity
   Fracture
SO JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; OPEN TIBIAL FRACTURES; INFECTION-RATE; FLAP
   COVERAGE; WOUND CONTROL; MANAGEMENT; TRAUMA; THERAPY; EXPERIENCE;
   DRESSINGS
AB Soft-tissue loss associated with lower extremity fracture poses a substantial reconstructive challenge. Following stabilization of life-threatening conditions and bony disruptions, the reconstructive team must address the soft-tissue envelope of the limb. The wound is managed with debridement followed by coverage. Coverage options range from basic to complex and include delayed primary closure, healing by secondary intention, skin grafting, local flap coverage, and distant tissue transfer. The choice of soft-tissue coverage method is based on its ability to provide an environment conducive to fracture healing. Understanding the merits and disadvantages of each reconstructive option helps to avoid undertreatment or overtreatment.
C1 [Friedrich, Jeffrey B.; Hanel, Douglas P.] Univ Washington, Div Plast Surg, Sch Med, Seattle, WA 98195 USA.
   [Friedrich, Jeffrey B.; Hanel, Douglas P.] Univ Washington, Sch Med, Dept Orthopaed & Sports Med, Seattle, WA USA.
   [Katolik, Leonid I.] Philadelphia Hand Ctr, Philadelphia, PA USA.
C3 University of Washington; University of Washington Seattle; University
   of Washington; University of Washington Seattle
RP Friedrich, JB (通讯作者)，Univ Washington, Div Plast Surg, Sch Med, Seattle, WA 98195 USA.
OI Friedrich, Jeffrey/0000-0002-5245-9708
CR Afifi AM, 2008, ANN PLAS SURG, V61, P430, DOI 10.1097/SAP.0b013e318160c165
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bhattacharyya T, 2008, PLAST RECONSTR SURG, V121, P1263, DOI 10.1097/01.prs.0000305536.09242.a6
   Bucalo Brian, 1993, Wound Repair and Regeneration, V1, P181, DOI 10.1046/j.1524-475X.1993.10308.x
   BYRD HS, 1981, PLAST RECONSTR SURG, V68, P73, DOI 10.1097/00006534-198107000-00015
   Falanga Vincent, 1992, Journal of Dermatology (Tokyo), V19, P667
   FISCHER MD, 1991, J BONE JOINT SURG AM, V73A, P1316, DOI 10.2106/00004623-199173090-00005
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   GRINNELL F, 1992, J INVEST DERMATOL, V98, P410, DOI 10.1111/1523-1747.ep12499839
   Hallock GG, 2000, J TRAUMA, V48, P913, DOI 10.1097/00005373-200005000-00016
   HENRY SL, 1990, J TRAUMA, V30, P1231, DOI 10.1097/00005373-199010000-00007
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Innes ME, 2001, BURNS, V27, P621, DOI 10.1016/S0305-4179(01)00015-8
   Keating JF, 1996, J ORTHOP TRAUMA, V10, P298, DOI 10.1097/00005131-199607000-00002
   LISTER G, 1988, J HAND SURG-AM, V13A, P22, DOI 10.1016/0363-5023(88)90193-1
   Llanos S, 2006, ANN SURG, V244, P700, DOI 10.1097/01.sla.0000217745.56657.e5
   MacKenzie EJ, 2005, J BONE JOINT SURG AM, V87A, P1801, DOI 10.2106/JBJS.E.00032
   MacKenzie Ellen J, 2006, J Am Acad Orthop Surg, V14, pS205
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   OSTERMANN PAW, 1993, CLIN ORTHOP RELAT R, P102
   Park JE, 2007, J TRAUMA, V62, P162, DOI 10.1097/01.ta.0000250599.84033.1f
   Parrett BM, 2006, PLAST RECONSTR SURG, V117, P1315, DOI 10.1097/01.prs.0000204959.18136.36
   PATZAKIS MJ, 1983, CLIN ORTHOP RELAT R, P36
   PATZAKIS MJ, 1989, CLIN ORTHOP RELAT R, P36
   Saffle JR, 2009, CLIN PLAST SURG, V36, P627, DOI 10.1016/j.cps.2009.05.005
   Schierle CF, 2009, PLAST RECONSTR SURG, V123, P1748, DOI 10.1097/PRS.0b013e3181a65a74
   Spector JA, 2007, PLAST RECONSTR SURG, V120, P952, DOI 10.1097/01.prs.0000255175.92201.c7
   Steiert AE, 2009, J PLAST RECONSTR AES, V62, P675, DOI 10.1016/j.bjps.2007.09.041
   SWARTZ WM, 1994, PLAST RECONSTR SURG, V93, P152, DOI 10.1097/00006534-199401000-00024
   Voineskos SH, 2009, PLAST RECONSTR SURG, V124, P298, DOI 10.1097/PRS.0b013e3181a8072f
   Webb LX, 2007, J BONE JOINT SURG AM, V89A, P923, DOI 10.2106/JBJS.F.00776
   YAREMCHUK MJ, 1987, PLAST RECONSTR SURG, V80, P1
   Zorrilla P, 2005, J TRAUMA, V59, P1515, DOI 10.1097/01.ta.0000199242.24511.30
NR 33
TC 18
Z9 28
U1 1
U2 7
PU AMER ACAD ORTHOPAEDIC SURGEONS
PI ROSEMENT
PA 6300 N RIVER ROAD, ROSEMENT, IL 60018-4262 USA
SN 1067-151X
J9 J AM ACAD ORTHOP SUR
JI J. Am. Acad. Orthop. Surg.
PD FEB
PY 2011
VL 19
IS 2
BP 81
EP 90
DI 10.5435/00124635-201102000-00003
PG 10
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 722IF
UT WOS:000287425200003
PM 21292931
DA 2026-07-24
ER

PT J
AU Shah, H
   Carstensen, T
   Kmeid, M
   Bialowas, C
AF Shah, Hemali
   Carstensen, Teresa
   Kmeid, Michel
   Bialowas, Christie
TI Cutaneous Blastomycosis Presenting as a Nonhealing Wound in the
   Northeast United States: A Case Report
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE blastomycosis; wound management; spider bite; nonhealing wound
ID THERAPY
AB Primary cutaneous blastomycosis is a rare presentation of infection caused by direct inoculation of a wound. We present a 61-year-old male with an extensive history of wound dehiscence and wound care noncompliance after a bite from a brown recluse spider on the left thigh while on vacation in Cape Cod in September of 2020. After antibiotic therapy and culture, treatment involved debridement, split thickness skin grafting, strict wound vacuum-assisted closure care, and oral itraconazole. This brief demonstrates a case of blastomycosis arising from trauma in a non-endemic region for infection and serves as an example of successful management of the longstanding wound.
C1 [Shah, Hemali] Albany Med Coll, Albany, NY USA.
   [Carstensen, Teresa; Bialowas, Christie] Albany Med Ctr, Div Plast & Reconstruct Surg, Albany, NY USA.
   [Kmeid, Michel] Albany Med Ctr, Dept Pathol, Albany, NY USA.
   [Shah, Hemali] Albany Med Coll, 47 New Scotland Ave, Albany, NY 12208 USA.
C3 Albany Medical College; Albany Medical College; Albany Medical College;
   Albany Medical College
RP Shah, H (通讯作者)，Albany Med Coll, 47 New Scotland Ave, Albany, NY 12208 USA.
EM shahh@amc.edu
RI Shah, Hemali/JAN-4348-2023
OI Shah, Hemali/0000-0002-8407-9339
CR Agha RA, 2016, INT J SURG, V34, P180, DOI 10.1016/j.ijsu.2016.08.014
   Azar MM, 2014, J CLIN MICROBIOL, V52, P1298, DOI 10.1128/JCM.03356-13
   Blume PA, 2010, INT WOUND J, V7, P480, DOI 10.1111/j.1742-481X.2010.00728.x
   Chapman SW, 2008, CLIN INFECT DIS, V46, P1801, DOI 10.1086/588300
   Elmas ÖF, 2020, DERMATOL PRACT CONCE, V10, DOI 10.5826/dpc.1003a54
   Fernandez-Flores A, 2014, AM J DERMATOPATH, V36, P531, DOI 10.1097/DAD.0b013e31829cc6f3
   Ladizinski B, 2018, J EMERG MED, V54, pE11, DOI 10.1016/j.jemermed.2017.09.034
   Lectercq A, 2016, ANN DERMATOL VENER, V143, P3, DOI 10.1016/j.annder.2015.06.022
   Mak J, 2018, J CUTAN MED SURG, V22, P519, DOI 10.1177/1203475418760460
   Motswaledi HM, 2012, INT J DERMATOL, V51, P1090, DOI 10.1111/j.1365-4632.2011.05369.x
   Ortega-Loayza AG, 2013, AN BRAS DERMATOL, V88, P287, DOI 10.1590/S0365-05962013000200022
   Owen WR, 2012, ADV SKIN WOUND CARE, V25, P321, DOI 10.1097/01.ASW.0000416005.78089.b0
   Tang XH, 2021, MYCOPATHOLOGIA, V186, P449, DOI 10.1007/s11046-021-00551-3
   Wang S, 2015, J AM ACAD DERMATOL, V73, pE169, DOI 10.1016/j.jaad.2015.07.024
   WILSON JW, 1955, ARCH DERMATOL, V71, P39, DOI 10.1001/archderm.1955.01540250041008
   Zhu D, 2017, INT J INFECT DIS, V59, P86, DOI 10.1016/j.ijid.2017.04.006
NR 16
TC 2
Z9 2
U1 0
U2 3
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD DEC
PY 2025
VL 24
IS 4
BP 1244
EP 1249
DI 10.1177/15347346221140782
EA NOV 2022
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 9IU0P
UT WOS:000890342900001
PM 36426539
DA 2026-07-24
ER

PT J
AU Schecter, WP
AF Schecter, William P.
TI Management of Enterocutaneous Fistulas
SO SURGICAL CLINICS OF NORTH AMERICA
LA English
DT Article
DE Enterocutaneous fistula; Enteroatmospheric fistula; Open abdomen;
   Abdominal wall reconstruction
ID VACUUM-ASSISTED CLOSURE; ABDOMINAL-WALL DEFECTS; CRITICALLY-ILL
   PATIENTS; OPEN ABDOMEN; EXTERNAL FISTULAS; RANDOMIZED-TRIAL; EXPOSED
   FISTULA; NUTRITION; IMMUNONUTRITION; OCTREOTIDE
AB Management of enterocutaneous fistulas (ECFs) involves (1) recognition and stabilization, (2) anatomic definition and decision, and (3) definitive operation. Phase 1 encompasses correction of fluid and electrolyte imbalance, skin protection, and nutritional support. Abdominal imaging defines the anatomy of the fistula in phase 2. ECFs that do not heal spontaneously require segmental resection of the bowel segment communicating with the fistula and restoration of intestinal continuity in phase 3. The enteroatmospheric fistula (EAF) is a malevolent condition requiring prolonged wound care and nutritional support. Complex abdominal wall reconstruction immediately following fistula resection is necessary for all EAFs.
C1 Univ Calif San Francisco, San Francisco Gen Hosp, Dept Surg, San Francisco, CA 94110 USA.
C3 University of California System; University of California San Francisco
RP Schecter, WP (通讯作者)，Univ Calif San Francisco, San Francisco Gen Hosp, Dept Surg, 1001 Potrero Ave,Ward 3A17, San Francisco, CA 94110 USA.
EM bschect@sfghsurg.ucsf.edu
CR AGUIRRE A, 1974, ANN SURG, V180, P393, DOI 10.1097/00000658-197410000-00003
   Al-Khoury G, 2008, J AM COLL SURGEONS, V206, P397, DOI 10.1016/j.jamcollsurg.2007.07.027
   Alivizatos V, 2002, HEPATO-GASTROENTEROL, V49, P1010
   Banwell P, 1998, BRIT J PLAST SURG, V51, P79, DOI 10.1016/S0007-1226(98)80142-2
   Beaumont William., 1838, EXPT OBSERVATIONS GA
   Berry SM, 1996, SURG CLIN N AM, V76, P1009, DOI 10.1016/S0039-6109(05)70495-3
   Bohrer JV, 1931, ANN SURG, V93, P1174, DOI 10.1097/00000658-193106000-00012
   BOWER RH, 1995, CRIT CARE MED, V23, P436, DOI 10.1097/00003246-199503000-00006
   BURCH JM, 1992, ANN SURG, V215, P476, DOI 10.1097/00000658-199205000-00010
   Byers P, 1997, J TRAUMA, V42, P800
   Campos ACL, 1999, J AM COLL SURGEONS, V188, P483, DOI 10.1016/S1072-7515(99)00038-1
   Chang SH, 2010, J PLAST RECONSTR AES, V63, P1055, DOI 10.1016/j.bjps.2009.10.024
   CHAPMAN R, 1964, AM J SURG, V108, P157, DOI 10.1016/0002-9610(64)90005-4
   Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
   Datta V, 2010, DIS COLON RECTUM, V53, P192, DOI 10.1007/DCR.0b013e3181b4c34a
   Dayton M, 2006, SURGERY, V140, P576
   de Weerd L, 2007, ANN PLAS SURG, V58, P580, DOI 10.1097/01.sap.0000237643.45125.8b
   Dorta G, 1999, DIGESTION, V60, P53, DOI 10.1159/000051481
   Draus JM, 2006, SURGERY, V140, P570, DOI 10.1016/j.surg.2006.07.003
   DUDRICK SJ, 1969, ANN SURG, V169, P974, DOI 10.1097/00000658-196906000-00018
   Dudrick SJ, 1999, WORLD J SURG, V23, P570, DOI 10.1007/PL00012349
   Eachempati SR, 2008, WORLD J SURG, V32, P444, DOI 10.1007/s00268-007-9358-y
   EDMUNDS LH, 1960, ANN SURG, V152, P445
   FAZIO VW, 1983, WORLD J SURG, V7, P481, DOI 10.1007/BF01655937
   FISCHER JE, 1983, WORLD J SURG, V7, P446, DOI 10.1007/BF01655932
   Fischer JE, 2008, AM J SURG, V196, P1, DOI 10.1016/j.amjsurg.2008.01.001
   Franklin C, 2010, J WOUND OSTOMY CONT, V37, P387, DOI 10.1097/WON.0b013e3181e3adb7
   GERZOF SG, 1979, AM J ROENTGENOL, V133, P1
   Girard S, 2002, AM J SURG, V184, P166, DOI 10.1016/S0002-9610(02)00916-9
   Gyorki DE, 2010, ANZ J SURG, V80, P178, DOI 10.1111/j.1445-2197.2009.05086.x
   HALVERSEN RC, 1969, AM J SURG, V118, P968, DOI 10.1016/0002-9610(69)90268-2
   Hardwicke Joseph, 2010, Ann R Coll Surg Engl, V92, pW12, DOI 10.1308/147870810X12659688851834
   Heyland DK, 2001, JAMA-J AM MED ASSOC, V286, P944, DOI 10.1001/jama.286.8.944
   HILL GL, 1983, WORLD J SURG, V7, P495, DOI 10.1007/BF01655939
   Hsu PW, 2009, J PLAST RECONSTR AES, V62, P1484, DOI 10.1016/j.bjps.2008.04.060
   IRVING M, 1985, ANN ROY COLL SURG, V67, P2
   Jamshidi R, 2007, ARCH SURG-CHICAGO, V142, P793, DOI 10.1001/archsurg.142.8.793
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   Johnson EK, 2007, MIL MED, V172, P1119, DOI 10.7205/MILMED.172.10.1119
   KEIGHLEY MRB, 1987, ACTA GASTRO-ENT BELG, V50, P580
   Koshima I, 1999, ANN PLAS SURG, V43, P199
   Kudsk KA, 1996, ANN SURG, V224, P531, DOI 10.1097/00000658-199610000-00011
   Kudsk KA, 1996, ANN SURG, V224, P542
   Kudsk KA, 2006, ANNU REV NUTR, V26, P463, DOI 10.1146/annurev.nutr.26.061505.111230
   Lattuada D, 2007, J NEUROIMMUNOL, V182, P153, DOI 10.1016/j.jneuroim.2006.10.007
   LEVY E, 1986, ANN CHIR, V40, P184
   Lloyd DAJ, 2006, BRIT J SURG, V93, P1045, DOI 10.1002/bjs.5396
   Makhdoom ZA, 2000, J CLIN GASTROENTEROL, V31, P195, DOI 10.1097/00004836-200010000-00003
   Marik PE, 2008, INTENS CARE MED, V34, P1980, DOI 10.1007/s00134-008-1213-6
   Martinez JL, 2008, WORLD J SURG, V32, P436, DOI 10.1007/s00268-007-9304-z
   MATHES SJ, 1977, BRIT J PLAST SURG, V30, P282, DOI 10.1016/0007-1226(77)90118-7
   Maurice SM, 2009, AM J SURG, V197, P35, DOI 10.1016/j.amjsurg.2007.11.019
   MCINTYRE PB, 1984, BRIT J SURG, V71, P293, DOI 10.1002/bjs.1800710416
   NUBIOLA P, 1989, ANN SURG, V210, P56, DOI 10.1097/00000658-198907000-00009
   PRICKETT D, 1991, SOUTHERN MED J, V84, P736, DOI 10.1097/00007611-199106000-00015
   Rao M, 2007, COLORECTAL DIS, V9, P266, DOI 10.1111/j.1463-1318.2006.01154.x
   REBER HA, 1978, ANN SURG, V188, P460, DOI 10.1097/00000658-197810000-00003
   Saffle JR, 1997, J TRAUMA, V42, P793, DOI 10.1097/00005373-199705000-00008
   SARFEH IJ, 1992, ARCH SURG-CHICAGO, V127, P1027
   SARFEH IJ, 1992, ARCH SURG-CHICAGO, V127, P1030
   Satya R, 2010, J VASC INTERV RADIOL, V21, P414, DOI 10.1016/j.jvir.2009.11.015
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   Schecter WP, 2009, J AM COLL SURGEONS, V209, P484, DOI 10.1016/j.jamcollsurg.2009.05.025
   SCHEIN M, 1990, BRIT J SURG, V77, P97, DOI 10.1002/bjs.1800770133
   Schein M, 2008, WORLD J SURG, V32, P336, DOI 10.1007/s00268-007-9411-x
   Schilling J, 1996, NUTRITION, V12, P423, DOI 10.1016/S0899-9007(96)00096-2
   Scott BG, 2005, SCAND J SURG, V94, P9, DOI 10.1177/145749690509400104
   Shestak KC, 2000, PLAST RECONSTR SURG, V105, P731, DOI 10.1097/00006534-200002000-00041
   Singh B, 2009, INT SURG, V94, P262
   SITGESSERRA A, 1982, BRIT J SURG, V69, P147, DOI 10.1002/bjs.1800690310
   Stanga Z, 2008, EUR J CLIN NUTR, V62, P687, DOI 10.1038/sj.ejcn.1602854
   Subramaniam MH, 2002, J TRAUMA, V53, P386, DOI 10.1097/00005373-200208000-00037
   Vianna Rodrigo M, 2008, Adv Surg, V42, P129, DOI 10.1016/j.yasu.2008.03.008
   Visschers RGJ, 2008, WORLD J SURG, V32, P445, DOI 10.1007/s00268-007-9371-1
   Wainstein Daniel Edgardo, 2008, World J Surg, V32, P430
   WIEDERMANN CJ, 1993, BLOOD, V82, P954
   Williams JK, 1998, PLAST RECONSTR SURG, V101, P713, DOI 10.1097/00006534-199803000-00020
NR 77
TC 52
Z9 63
U1 0
U2 10
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0039-6109
EI 1558-3171
J9 SURG CLIN N AM
JI Surg. Clin.-North Am.
PD JUN
PY 2011
VL 91
IS 3
BP 481
EP +
DI 10.1016/j.suc.2011.02.004
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 784PT
UT WOS:000292170000004
PM 21621692
DA 2026-07-24
ER

PT J
AU Jones, SM
   Banwell, PE
   Shakespeare, PG
AF Jones, SM
   Banwell, PE
   Shakespeare, PG
TI Advances in wound healing: topical negative pressure therapy
SO POSTGRADUATE MEDICAL JOURNAL
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; SUBATMOSPHERIC PRESSURE; STRESS; TRIAL; SWINE;
   SKIN
AB In clinical practice many wounds are slow to heal and difficult to manage. The recently introduced technique of topical negative pressure therapy (TNP) has been developed to try to overcome some of these difficulties. TNP applies a controlled negative pressure to the surface of a wound that has potential advantages for wound treatment and management. Although the concept itself, of using suction in wound management is not new, the technique of applying a negative pressure at the surface of the wound is. This paper explores the origins and proposed mechanisms of action of TNP therapy and discusses the types of wounds that are thought to benefit most from use of this system.
C1 Salisbury Dist Hosp, Laing Lab, Odstock Burns & Wound Healing Charitable Trust, Salisbury SP2 8BJ, Wilts, England.
C3 Salisbury District Hospital
RP Jones, SM (通讯作者)，Salisbury Dist Hosp, Laing Lab, Odstock Burns & Wound Healing Charitable Trust, Salisbury SP2 8BJ, Wilts, England.
EM Sophie.Jones@nhs.net
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Banwell P E, 2003, J Wound Care, V12, P22
   BANWELL PE, IN PRESS J WOUND CAR
   Beitz J M, 2001, Ostomy Wound Manage, V47, P33
   BRUNETTE DM, 1984, J CELL SCI, V69, P35
   Büttgenbach S, 2001, MICROSYST TECHNOL, V7, P165, DOI 10.1007/s005420000082
   CURTIS ASG, 1978, NATURE, V274, P52, DOI 10.1038/274052a0
   EVANS D, 2001, COCHRANE LIB
   Fabian TS, 2000, AM SURGEON, V66, P1136
   Fay M F, 1987, AORN J, V46, P442, DOI 10.1016/S0001-2092(07)66456-4
   Fleischmann W, 1995, Eur J Orthop Surg Traumatol, V5, P37, DOI 10.1007/BF02716212
   FOX JW, 1976, AM J SURG, V132, P673, DOI 10.1016/0002-9610(76)90372-X
   Garner GB, 2001, AM J SURG, V182, P630, DOI 10.1016/S0002-9610(01)00786-3
   Giovanni UM, 2002, PLAST RECONSTR SURG, V109, P1747, DOI 10.1097/00006534-200204150-00054
   Greer SE, 1999, ANN PLAS SURG, V43, P551, DOI 10.1097/00000637-199911000-00016
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Ichioka S, 1997, J SURG RES, V72, P29, DOI 10.1006/jsre.1997.5170
   Joseph E, 2000, WOUNDS, V12, P60
   LEVIN LS, 1993, ORTHOP CLIN N AM, V24, P393
   Morykwas MJ, 1999, J BURN CARE REHABIL, V20, P15, DOI 10.1097/00004630-199901001-00003
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Philbeck T E Jr, 1999, Ostomy Wound Manage, V45, P41
   PORTER R, 2002, SURG BLOOD GUTS SHOR, P109
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   Sibbald R Gary, 2003, Ostomy Wound Manage, V49, P52
   URSCHEL JD, 1988, BRIT J PLAST SURG, V41, P182, DOI 10.1016/0007-1226(88)90049-5
   WINTER GD, 1962, NATURE, V193, P293, DOI 10.1038/193293a0
NR 29
TC 54
Z9 72
U1 0
U2 6
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0032-5473
EI 1469-0756
J9 POSTGRAD MED J
JI Postgrad. Med. J.
PD JUN
PY 2005
VL 81
IS 956
BP 353
EP 357
DI 10.1136/pgmj.2004.026351
PG 5
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 932UR
UT WOS:000229580000002
PM 15937199
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Bribriesco, A
   Patterson, GA
AF Bribriesco, Alejandro
   Patterson, G. Alexander
TI Management of Postpneumonectomy Bronchopleural Fistula: From
   Thoracoplasty to Transsternal Closure
SO THORACIC SURGERY CLINICS
LA English
DT Article
DE Pneumonectomy; Bronchopleural fistula; Postpneumonectomy empyema; Open
   window thoracotomy; Clagett procedure; Thoracoplasty
ID OPEN WINDOW THORACOSTOMY; VACUUM-ASSISTED CLOSURE; BRONCHIAL STUMP
   COVERAGE; CELL LUNG-CANCER; TRANSPERICARDIAL APPROACH; ACCELERATED
   TREATMENT; CLAGETT PROCEDURE; RISK-FACTORS; EMPYEMA; PNEUMONECTOMY
AB Development of postpneumonectomy empyema with bronchopleural fistula is a life threatening condition that requires prompt action. Although measures should be taken to prevent bronchopleural fistula at the time of pneumonectomy, many patients experience this complication. Management focuses on drainage of the pleural space, control of the pleural infection including repair of the bronchopleural fistula, and obliteration of the residual pleural cavity. Multiple techniques and procedures have been developed over time to achieve these goals. Knowledge of the diverse therapeutic options is important to select the optimal treatment for these complex patients.
C1 [Bribriesco, Alejandro] Cleveland Clin, Inst Heart & Vasc, Dept Thorac & Cardiovasc Surg, 9500 Euclid Ave,J4-1, Cleveland, OH 44195 USA.
   [Patterson, G. Alexander] Washington Univ, Div Cardiothorac Surg, 660 South Euclid,Campus Box 8234, St Louis, MO 63110 USA.
C3 Cleveland Clinic Foundation; Washington University (WUSTL)
RP Bribriesco, A (通讯作者)，Cleveland Clin, Inst Heart & Vasc, Dept Thorac & Cardiovasc Surg, 9500 Euclid Ave,J4-1, Cleveland, OH 44195 USA.
EM bribria@ccf.org
RI Bribriesco, Alejandro/AAV-1591-2020
CR ABRUZZINI P, 1961, CHIR TORAC, V14, P165
   Ahmad U, 2017, ANN THORAC SURG, V104, pE215, DOI 10.1016/j.athoracsur.2017.04.015
   Alexander J., 1937, COLLAPSE THERAPY PUL, P1
   Algar FJ, 2001, ANN THORAC SURG, V72, P1662, DOI 10.1016/S0003-4975(01)03096-X
   ANDERSON TM, 1995, ANN THORAC SURG, V60, P729, DOI 10.1016/0003-4975(95)00500-K
   ANDREWS NC, 1961, J THORAC CARDIOV SUR, V41, P809
   ASAMURA H, 1992, J THORAC CARDIOV SUR, V104, P1456
   Azorin JF, 1996, CHEST, V109, P1097, DOI 10.1378/chest.109.4.1097
   BALDWIN JC, 1985, J THORAC CARDIOV SUR, V90, P813
   BELTRAMI V, 1989, CHEST, V95, P379, DOI 10.1378/chest.95.2.379
   Bergeron EJ, 2017, THORAC SURG CLIN, V27, P87, DOI 10.1016/j.thorsurg.2017.01.002
   Boudaya MS, 2013, J THORAC CARDIOV SUR, V146, P575, DOI 10.1016/j.jtcvs.2013.04.023
   Cerfolio RJ, 1997, ANN THORAC SURG, V64, P958
   CLAGETT OT, 1963, J THORAC CARDIOV SUR, V45, P141, DOI 10.1016/S0022-5223(19)32877-6
   Daly BDT, 2006, ANN THORAC SURG, V82, P227, DOI 10.1016/j.athoracsur.2006.02.061
   delaRiviere AB, 1997, ANN THORAC SURG, V64, P954
   Deschamps C, 1996, Chest Surg Clin N Am, V6, P519
   Deschamps C, 2001, Semin Thorac Cardiovasc Surg, V13, P13
   Deschamps C, 2001, ANN THORAC SURG, V72, P243, DOI 10.1016/S0003-4975(01)02681-9
   Deslauriers J GJ, 2008, PEARSONS THORACIC ES, P1159
   Deslauriers Jean, 2002, Chest Surg Clin N Am, V12, P605, DOI 10.1016/S1052-3359(02)00017-0
   Deslauriers J, 2015, ANN THORAC SURG, V100, P1153, DOI 10.1016/j.athoracsur.2015.08.028
   Di Maio M, 2015, EUR J CARDIO-THORAC, V48, P196, DOI 10.1093/ejcts/ezu381
   Eloesser L, 1935, SURG GYNECOL OBSTET, V60, P1096
   Estlander JA, 1891, REV MENS, V8, P885
   García-Yuste M, 2007, EUR J CARDIO-THORAC, V31, P192, DOI 10.1016/j.ejcts.2006.11.031
   Gharagozloo F, 1998, J THORAC CARDIOV SUR, V116, P943, DOI 10.1016/S0022-5223(98)70044-3
   Ginsberg R J, 2001, Semin Thorac Cardiovasc Surg, V13, P20
   GINSBERG RJ, 1989, ANN THORAC SURG, V47, P231, DOI 10.1016/0003-4975(89)90276-2
   GOLDSTRAW P, 1979, THORAX, V34, P740, DOI 10.1136/thx.34.6.740
   Gossot D, 2004, ANN THORAC SURG, V78, P273, DOI 10.1016/j.athoracsur.2004.02.023
   Graham EA, 1933, J AMER MED ASSOC, V101, P1371, DOI 10.1001/jama.1933.02740430017005
   GREGOIRE R, 1987, CAN J SURG, V30, P343
   Groth SS, 2010, J THORAC CARDIOV SUR, V140, P244, DOI 10.1016/j.jtcvs.2009.08.015
   Hollaus PH, 1999, EUR J CARDIO-THORAC, V16, P283, DOI 10.1016/S1010-7940(99)00224-9
   Hollaus PH, 1997, ANN THORAC SURG, V63, P1391, DOI 10.1016/S0003-4975(97)00409-8
   Hu XF, 2013, ANN THORAC SURG, V96, P419, DOI 10.1016/j.athoracsur.2013.04.050
   Hysi I, 2011, ANN THORAC SURG, V92, P1833, DOI 10.1016/j.athoracsur.2011.07.004
   Klepetko W, 1999, EUR J CARDIO-THORAC, V15, P758, DOI 10.1016/S1010-7940(99)00089-5
   Lewis C., 2000, OPER TECH THORAC CAR, V5, P135, DOI [10.1053/otct.2000.8937, DOI 10.1053/OTCT.2000.8937]
   Lois M, 2005, CHEST, V128, P3955, DOI 10.1378/chest.128.6.3955
   Martin J, 2001, ANN THORAC SURG, V72, P1149, DOI 10.1016/S0003-4975(01)02995-2
   Massera F, 2006, ANN THORAC SURG, V82, P288, DOI 10.1016/j.athoracsur.2005.11.046
   Mazzella A, 2018, SEMIN THORAC CARDIOV, V30, P104, DOI 10.1053/j.semtcvs.2017.10.003
   MILLER JI, 1984, ANN THORAC SURG, V38, P227, DOI 10.1016/S0003-4975(10)62243-6
   PADHI RK, 1960, J THORAC CARDIOV SUR, V39, P385
   PAIROLERO PC, 1990, J THORAC CARDIOV SUR, V99, P958
   Perentes JY, 2015, J THORAC CARDIOV SUR, V149, P745, DOI 10.1016/j.jtcvs.2014.10.052
   Petrella F, 2015, NEW ENGL J MED, V372, P96, DOI 10.1056/NEJMc1411374
   Pforr A, 2016, ANN THORAC SURG, V101, P287, DOI 10.1016/j.athoracsur.2015.06.026
   Regnard JF, 2000, J THORAC CARDIOV SUR, V120, P270, DOI 10.1067/mtc.2000.106837
   Robinson S, 1916, SURG GYNECOL OBSTET, V64
   Rocco G, 2012, EUR J CARDIO-THORAC, V41, P1069, DOI 10.1093/ejcts/ezr196
   Schede M, 1890, VERHANDL C INNERE ME, P41
   Schneiter D, 2002, EUR J CARDIO-THORAC, V21, P644, DOI 10.1016/S1010-7940(02)00043-X
   Schneiter D, 2001, ANN THORAC SURG, V72, P1668, DOI 10.1016/S0003-4975(01)03083-1
   Schneiter D, 2008, J THORAC CARDIOV SUR, V136, P179, DOI 10.1016/j.jtcvs.2008.01.036
   SHAMJI FM, 1983, J THORAC CARDIOV SUR, V86, P818
   Siegel HJ, 2007, J SURG ONCOL, V96, P575, DOI 10.1002/jso.20846
   STAFFORD EG, 1972, J THORAC CARDIOV SUR, V63, P771, DOI 10.1016/S0022-5223(19)41848-5
   Stamatis G, 1996, EUR J CARDIO-THORAC, V10, P83, DOI 10.1016/S1010-7940(96)80128-X
   Stefani A, 2011, ANN THORAC SURG, V91, P263, DOI 10.1016/j.athoracsur.2010.07.084
   Taghavi S, 2005, ANN THORAC SURG, V79, P284, DOI 10.1016/j.athoracsur.2004.06.108
   Topcuoglu MS, 2000, ANN THORAC SURG, V69, P394, DOI 10.1016/S0003-4975(99)01355-7
   Toufektzian L, 2015, INTERACT CARDIOV TH, V21, P379, DOI 10.1093/icvts/ivv149
   Venissac N, 2006, J THORAC CARDIOV SUR, V132, P1490, DOI 10.1016/j.jtcvs.2006.08.013
   VIRKKULA L, 1974, SCAND J THORAC CARD, V8, P133, DOI 10.3109/14017437409130746
   Wain J C, 1996, Chest Surg Clin N Am, V6, P529
   WEISSBERG D, 1982, CHEST, V82, P447, DOI 10.1378/chest.82.4.447
   Welvaart Willem N, 2009, Interact Cardiovasc Thorac Surg, V8, P558, DOI 10.1510/icvts.2008.196485
   WONG PS, 1994, EUR J CARDIO-THORAC, V8, P345, DOI 10.1016/1010-7940(94)90027-2
   Wright CD, 1996, J THORAC CARDIOV SUR, V112, P1367, DOI 10.1016/S0022-5223(96)70153-8
   Zaheer S, 2006, ANN THORAC SURG, V82, P279, DOI 10.1016/j.athoracsur.2006.01.052
   Zakkar M, 2014, INTERACT CARDIOV TH, V18, P488, DOI 10.1093/icvts/ivt502
NR 74
TC 39
Z9 52
U1 0
U2 4
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1547-4127
J9 THORAC SURG CLIN
JI Thorac. Surg. Clin.
PD AUG
PY 2018
VL 28
IS 3
BP 323
EP +
DI 10.1016/j.thorsurg.2018.05.008
PN 2
PG 14
WC Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System; Surgery
GA GS3LI
UT WOS:000443507700012
PM 30054070
DA 2026-07-24
ER

PT J
AU Lahouel, N
   Mokwatlo, P
   Ndobe, E
AF Lahouel, N.
   Mokwatlo, P.
   Ndobe, E.
TI Coverage of extensive tibial bone exposure in burn patients with three
   local flaps
SO SOUTH AFRICAN JOURNAL OF SURGERY
LA English
DT Article
DE hemisoleus flap; lower limb burns; medial gastrocnemius flap; tibial
   bone exposure; tibialis anterior flap
ID VACUUM-ASSISTED CLOSURE; LOWER-EXTREMITY TRAUMA; ANTERIOR MUSCLE;
   THROMBOCYTOSIS; MANAGEMENT; HEEL
AB Covering tibial bone exposure from third degree burns to the lower limbs is a challenging task for the plastic surgeon. We present our experience of covering tibial exposure from burns in three different patients, where four limbs were involved and three muscular flaps were used in conjunction with one another; i.e. the tibialis anterior flap, the medial gastrocnemius flap and the hemisoleus flap. Through the use of this technique, tibial bone exposure, ranging from 15-30 cm, was successfully covered. This technique constitutes a good solution for surgically challenging wounds.
C1 [Lahouel, N.; Mokwatlo, P.; Ndobe, E.] Univ Witwatersrand, Dept Plast Reconstruct & Aesthet Surg, Johannesburg, South Africa.
C3 University of Witwatersrand
RP Lahouel, N (通讯作者)，Univ Witwatersrand, Dept Plast Reconstruct & Aesthet Surg, Johannesburg, South Africa.
EM nebil.lahouel@gmail.com
CR Ayyappan T, 2002, PLAST RECONSTR SURG, V109, P2307, DOI 10.1097/00006534-200206000-00022
   Benito-Ruiz J, 2004, ANN PLAS SURG, V52, P380, DOI 10.1097/01.sap.0000105520.24063.bb
   Browner BD, 2003, SKELETAL TRAUMA BASI, V1, P2132
   Casey R, 1987, LAMBEAUX MUSCULAIRES, P28
   Chang J, 1997, BURNS, V23, P69, DOI 10.1016/S0305-4179(96)00057-5
   Choe EI, 1996, ANN PLAS SURG, V36, P489, DOI 10.1097/00000637-199605000-00010
   Ford CN, 2002, ANN PLAS SURG, V49, P55, DOI 10.1097/00000637-200207000-00009
   HIRSHOWITZ B, 1987, PLAST RECONSTR SURG, V79, P407, DOI 10.1097/00006534-198703000-00016
   Lineaweaver VC, 1999, PLAST RECONSTR SURG, V103, P1553
   Margiotta MS, 1998, ANN PLAS SURG, V40, P463, DOI 10.1097/00000637-199805000-00003
   MATHES SJ, 1980, PLAST RECONSTR SURG, V66, P242, DOI 10.1097/00006534-198008000-00013
   Nugent N, 2005, BURNS, V31, P390, DOI 10.1016/j.burns.2004.10.019
   Rios-Luna A, 2008, J ORTHOP, V42, P387
   Sood R, 2003, J BURN CARE REHABIL, V24, P386, DOI 10.1097/01.BCR.0000095511.20154.94
NR 14
TC 1
Z9 1
U1 0
U2 2
PU SA MEDICAL ASSOC
PI PRETORIA
PA BLOCK F CASTLE WALK CORPORATE PARK, NOSSOB STREET, ERASMUSKLOOF EXT3,
   PRETORIA, 0002, SOUTH AFRICA
SN 0038-2361
EI 2078-5151
J9 S AFR J SURG
JI South Afr. J. Surg.
PD NOV
PY 2016
VL 54
IS 4
BP 58
EP 64
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA EJ5AJ
UT WOS:000393228600014
PM 28272859
DA 2026-07-24
ER

PT J
AU Corraretti, G
   Meulyzer, M
   Gustafsson, K
AF Corraretti, Giorgio
   Meulyzer, Michael
   Gustafsson, Kajsa
TI Treatment of fistulous cranial nuchal bursitis by complete surgical
   resection in two horses
SO EQUINE VETERINARY EDUCATION
LA English
DT Article
DE fistula; horse; nuchal bursa; nuchal bursitis; poll evil
ID VACUUM-ASSISTED CLOSURE; MANAGEMENT; ARTHRITIS; NECK
AB Equine fistulous cranial nuchal bursitis, also known as poll evil, is a serious condition that can progress to cause neurological symptoms and tetraparesis. To date, the only reported effective surgical technique to treat this condition includes the resection of a large portion of the nuchal ligament. This appears to be an outdated and overly invasive surgery with current standards. This case report describes a previously unreported surgical technique, consisting of resection of the entire cranial nuchal bursa under standing sedation and local analgesia. Two horses treated using this technique both had resolution of clinical signs and were able to return to their intended use.
C1 [Corraretti, Giorgio; Meulyzer, Michael; Gustafsson, Kajsa] Equine Clin Morette, Asse, Belgium.
   [Gustafsson, Kajsa] Univ Milan, Dept Vet Med DIMEVET, Sect Vet Surg, Lodi, Italy.
C3 University of Milan
RP Corraretti, G (通讯作者)，Equine Clin Morette, Asse, Belgium.
EM giorgio.corraretti@gmail.com
OI Gustafsson, Kajsa/0000-0002-0773-0829; Corraretti,
   Giorgio/0000-0001-6795-3330
CR Abuja GA, 2014, EQUINE VET J, V46, P745, DOI 10.1111/evj.12226
   Banasiewicz T, 2011, VIDEOSURGERY MINIINV, V6, P155, DOI 10.5114/wiitm.2011.24694
   Bergren AL, 2018, EQUINE VET J, V50, P465, DOI 10.1111/evj.12787
   Budras K.D., 2013, ANATOMY HORSE ILLUST, P50
   Cárdenas L, 2019, TRANSBOUND EMERG DIS, V66, P1280, DOI 10.1111/tbed.13144
   Durham M, 2011, DIAGNOSIS MANAGEMENT, P88
   Dyson SJ., 2011, DIAGNOSIS MANAGEMENT, V2nd, P606
   Eur-lex.europa.eu, 2021, EUR LEX 32003D0467 E
   García-López JM, 2010, JAVMA-J AM VET MED A, V237, P823, DOI 10.2460/javma.237.7.823
   GAUGHAN EM, 1988, J AM VET MED ASSOC, V193, P964
   Gemeinhardt KD, 2005, EQUINE VET EDUC, V17, P27, DOI 10.1111/j.2042-3292.2005.tb00331.x
   Gruber Brian F, 2008, J Knee Surg, V21, P180
   Hawkins JF, 2000, J AM VET MED ASSOC, V217, P74, DOI 10.2460/javma.2000.217.74
   HONNAS CM, 1995, J AM VET MED ASSOC, V206, P1022
   KAWANA S, 1995, DERMATOLOGY, V190, P35, DOI 10.1159/000246631
   MARTENS RJ, 1986, J AM VET MED ASSOC, V188, P582
   MCILWRAITH CW, 1983, VET CLIN N AM-LARGE, V5, P363
   Merrilat L.A., 1917, FISTULA WITHERS POLL, P8
   MORRIS PG, 1980, COMP CONT ED PRACT S, V2, P207
   Mudge M. C., 2019, Equine surgery, P41
   Ragnaud JM, 1996, CLIN INFECT DIS, V22, P374, DOI 10.1093/clinids/22.2.374
   Schramme M., 2019, Equine surgery, V5th, P1399
   Sisson S., 1975, Sisson and Grossman's The Anatomy of the Domestic Animals, V5, P349
   Wagner WD, 2010, PFERDEHEILKUNDE, V26, P367, DOI 10.21836/PEM20100306
NR 24
TC 5
Z9 5
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0957-7734
EI 2042-3292
J9 EQUINE VET EDUC
JI Equine Vet. Educ.
PD MAY
PY 2023
VL 35
IS 5
BP e391
EP e397
DI 10.1111/eve.13735
EA NOV 2022
PG 7
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA D5CA8
UT WOS:000888922200001
DA 2026-07-24
ER

PT J
AU Siegel, HJ
AF Siegel, Herrick J.
TI Management of Open Wounds Lessons from Orthopedic Oncology
SO ORTHOPEDIC CLINICS OF NORTH AMERICA
LA English
DT Article
DE Sarcoma; Wound complications; Hyperbaric oxygen treatment; Silver
   dressings
ID HYPERBARIC-OXYGEN; SILVER-NITRATE; NANOCRYSTALLINE SILVER; RESISTANCE;
   TISSUE; ANTIBACTERIAL; DRESSINGS; COMPLICATIONS; THERAPY; CLOSURE
AB The management of complex wounds remains a challenge, and although there have been many promising advances, patients often undergo a morbid and lengthy process to obtain sufficient, satisfactory healing. Sarcoma patients are especially vulnerable to soft tissue wound-healing complications. These patients are often treated with neoadjuvant radiation and/or chemotherapy and have compromised local vascularity to healing tissue. The advent and refinement of wound vacuum-assisted closure technology have been shown to have a tremendous impact. This article reviews the benefits of some novel technologies currently undergoing investigation in orthopedic oncology that will likely have applications in wound management from other causes.
C1 Univ Alabama Birmingham, Med Ctr, Birmingham, AL 35294 USA.
C3 University of Alabama System; University of Alabama Birmingham
RP Siegel, HJ (通讯作者)，Univ Alabama Birmingham, Med Ctr, Birmingham, AL 35294 USA.
EM hsiegel@uabmc.edu
FU Stryker; Corin
FX Paid consultant for Stryker and Corin.
CR Bickels J, 2005, CLIN ORTHOP RELAT R, P346, DOI 10.1097/01.blo.0000180450.21350.3e
   Burrell Robert E, 2003, Ostomy Wound Manage, V49, P19
   CASON JS, 1966, BMJ-BRIT MED J, V2, P1288, DOI 10.1136/bmj.2.5525.1288
   COWARD JE, 1973, CHEMOTHERAPY, V19, P348, DOI 10.1159/000221475
   Davidge KM, 2010, ANN SURG ONCOL, V17, P1052, DOI 10.1245/s10434-010-0915-5
   Dennog C, 1999, MUTAT RES-FUND MOL M, V428, P83, DOI 10.1016/S1383-5742(99)00034-4
   Dennog C, 1996, MUTAGENESIS, V11, P605, DOI 10.1093/mutage/11.6.605
   Doctor N, 1992, J Postgrad Med, V38, P112
   Dunn K, 2004, BURNS, V30, pS1, DOI 10.1016/S0305-4179(04)90000-9
   Feldmeier JJ., 2004, WOUND CARE PRACTICE, P369
   Gesell LaurieB., 2008, Hyperbaric Oxygen Therapy Indications, V12th
   Goldman RJ, 2009, PM&R, V1, P471, DOI 10.1016/j.pmrj.2009.03.012
   Jing HM, 2008, J BIOMED MATER RES A, V87A, P33, DOI 10.1002/jbm.a.31688
   Jones S, 2005, WOUNDS, V17, P263
   Jones SA, 2004, WOUND REPAIR REGEN, V12, P288, DOI 10.1111/j.1067-1927.2004.012304.x
   Lam PK, 2004, BRIT J BIOMED SCI, V61, P125, DOI 10.1080/09674845.2004.11732656
   Lansdown A B G, 2004, J Wound Care, V13, P131
   Lansdown ABG, 1997, BRIT J DERMATOL, V137, P728
   Liau SY, 1997, LETT APPL MICROBIOL, V25, P279, DOI 10.1046/j.1472-765X.1997.00219.x
   Malliard JY, 2012, CRIT REV MICROBIOL
   MARX RE, 1990, AM J SURG, V160, P519, DOI 10.1016/S0002-9610(05)81019-0
   MARX RE, 1999, HYPERBARIC MED PRACT, P665
   Mathieu D., 2006, HDB HYPERBARIC MED
   Neuman T.S., 2008, Physiology and Medicine of Hyperbaric Oxygen Therapy E-Book
   Nies DH, 1999, APPL MICROBIOL BIOT, V51, P730, DOI 10.1007/s002530051457
   Parsons D, 2005, WOUNDS, V17, P222
   Percival SL, 2005, J HOSP INFECT, V60, P1, DOI 10.1016/j.jhin.2004.11.014
   RICHARDS RME, 1991, J PHARM SCI, V80, P861, DOI 10.1002/jps.2600800912
   RICHARDS RME, 1981, MICROBIOS, V31, P83
   Rosenberg LA, 2013, INT J RADIAT ONCOL, V85, P432, DOI 10.1016/j.ijrobp.2012.04.037
   Russell A D, 1994, Prog Med Chem, V31, P351
   Sibbald R G, 2001, Ostomy Wound Manage, V47, P38
   Siegel HJ, 2007, J SURG ONCOL, V96, P575, DOI 10.1002/jso.20846
   Siegel HJ, CLIN ORTHOP IN PRESS
   Silver S, 2003, FEMS MICROBIOL REV, V27, P341, DOI 10.1016/S0168-6445(03)00047-0
   SILVERSTEIN P, 1992, AM J MED, V93, pS22, DOI 10.1016/0002-9343(92)90623-J
   Thom S., 1989, J Intensive Care Med, V4, P58, DOI [10.1177/088506668900400204, DOI 10.1177/088506668900400204]
   Valko M, 2007, INT J BIOCHEM CELL B, V39, P44, DOI 10.1016/j.biocel.2006.07.001
   Walker M, 2006, OSTOMY WOUND MANAG, V52, P42
   Wright JB, 1999, AM J INFECT CONTROL, V27, P344, DOI 10.1016/S0196-6553(99)70055-6
NR 40
TC 9
Z9 11
U1 0
U2 7
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0030-5898
EI 1558-1373
J9 ORTHOP CLIN N AM
JI Orthop. Clin. North Am.
PD JAN
PY 2014
VL 45
IS 1
BP 99
EP +
DI 10.1016/j.ocl.2013.08.006
PG 10
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 278VH
UT WOS:000328917500014
PM 24267211
DA 2026-07-24
ER

PT J
AU Clavijo-Alvarez, JA
AF Clavijo-Alvarez, Julio A.
TI Novel Technique for Skin Grafting Parastomal Wounds Using a
   Negative-Pressure Dressing
SO ADVANCES IN SKIN & WOUND CARE
LA English
DT Editorial Material
DE stoma; colostomy; parastomal; skin graft; negative-pressure dressing
ID VACUUM-ASSISTED CLOSURE; SURVIVAL; THERAPY; DEVICE; TRIAL
AB Grafting parastomal wounds remains a challenging procedure because of frequent contamination, difficulty isolating the grafted area from the stoma, and an unfavorable environment for skin graft take. The use of negative-pressure dressings has been shown to improve skin graft take by removing excess fluid between the graft and the wound bed, thereby accelerating engraftment.(1) The benefits of negative-pressure dressing around a stoma, however, may be hindered by vacuuming stool into the dressed area. This article reviews a novel approach used for the isolation of a stoma from the parastomal wound area to increase skin graft take in an 82-year-old woman.
C1 [Clavijo-Alvarez, Julio A.] Aest Plast Surg Associates, Greensburg, PA 15601 USA.
   [Clavijo-Alvarez, Julio A.] Univ Pittsburgh, Dept Plast Surg, Pittsburgh, PA 15260 USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); University
   of Pittsburgh
RP Clavijo-Alvarez, JA (通讯作者)，Aest Plast Surg Associates, Greensburg, PA 15601 USA.
CR Azzopardi EA, 2013, ANN PLAS SURG, V70, P23, DOI 10.1097/SAP.0b013e31826eab9e
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Degnim AC, 2013, ANN SURG, V258, P240, DOI 10.1097/SLA.0b013e31828c0b85
   Isago T, 2003, J DERMATOL, V30, P673, DOI 10.1111/j.1346-8138.2003.tb00456.x
   Moisidis E, 2004, PLAST RECONSTR SURG, V114, P917, DOI 10.1097/01.PRS.0000133168.57199.E1
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Stanley BJ, 2013, VET SURG, V42, P511, DOI 10.1111/j.1532-950X.2013.12005.x
   Tominaga GT, 2002, ARCH SURG-CHICAGO, V137, P933
   Ward C, 2012, J TRAUMA ACUTE CARE, V73, P447, DOI 10.1097/TA.0b013e31825aa9ea
NR 9
TC 1
Z9 1
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1527-7941
EI 1538-8654
J9 ADV SKIN WOUND CARE
JI Adv. Skin Wound Care
PD JUN
PY 2014
VL 27
IS 6
BP 256
EP 258
DI 10.1097/01.ASW.0000446863.19183.47
PG 3
WC Dermatology; Nursing; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing; Surgery
GA AI3AD
UT WOS:000336729700003
PM 24836615
DA 2026-07-24
ER

PT J
AU Scharf, VF
AF Scharf, Valery F.
TI Free Grafts and Microvascular Anastomoses
SO VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
LA English
DT Article
DE Free grafts; Free skin flaps; Microvascular anastomoses; Wounds;
   Engraftment
ID VACUUM-ASSISTED CLOSURE; THICKNESS SKIN-GRAFTS; FREE TISSUE TRANSFER;
   NEGATIVE-PRESSURE DRESSINGS; FULL-THICKNESS; CONTROLLED-TRIAL; DOGS;
   THERAPY; WOUNDS; FOUNDATION
AB Skin grafts and free skin flaps are useful options for closure of wounds in which primary closure or use of traditional skin flaps is not feasible. Grafts are classified by their morphology and host-donor relationship. Free skin flaps with microvascular anastomoses are developed from previously described axial pattern flaps and have the added advantage of reestablishing robust vascular supply to the flap, but require specialized equipment and a high degree of technical expertise. Despite intensive perioperative care and the risk of graft or flap failure, skin grafts and free skin flaps can serve as rewarding methods of closing difficult wounds.
C1 [Scharf, Valery F.] North Carolina State Univ, Coll Vet Med, Small Anim Soft Tissue Surg, Dept Clin Sci, 1060 William Moore Dr, Raleigh, NC 27606 USA.
C3 North Carolina State University
RP Scharf, VF (通讯作者)，North Carolina State Univ, Coll Vet Med, Small Anim Soft Tissue Surg, Dept Clin Sci, 1060 William Moore Dr, Raleigh, NC 27606 USA.
EM vfscharf@ncsu.edu
CR BAUER MS, 1986, VET SURG, V15, P321, DOI 10.1111/j.1532-950X.1986.tb00235.x
   Ben-Amotz R, 2007, VET SURG, V36, P684, DOI 10.1111/j.1532-950X.2007.00321.x
   Bhandal J, 2012, VET SURG, V41, P448, DOI 10.1111/j.1532-950X.2012.00987.x
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Bohling M.W., 2012, Veterinary Surgery Small Animal, V1st, P1271
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   BROWNE EZ, 1986, HAND CLIN, V2, P353
   Calfee EF, 2002, VET SURG, V31, P32, DOI 10.1053/jvet.2002.29455
   Chang KP, 2001, BURNS, V27, P839, DOI 10.1016/S0305-4179(01)00052-3
   CONVERSE JM, 1975, BRIT J PLAST SURG, V28, P274, DOI 10.1016/0007-1226(75)90031-4
   Degner DA, 2005, VET SURG, V34, P297, DOI 10.1111/j.1532-950X.2005.00047.x
   Fowler JD, 1998, VET SURG, V27, P406, DOI 10.1111/j.1532-950X.1998.tb00147.x
   Grabb WC, 1991, GRABB SMITHS PLASTIC, P3
   Green ML, 2008, J AM ANIM HOSP ASSOC, V44, P218, DOI 10.5326/0440218
   Harris JE, 2008, VET COMP ORTHOPAED, V21, P378, DOI 10.3415/VCOT-07-04-0029
   HARRISON DH, 1981, PLAST RECONSTR SURG, V68, P543, DOI 10.1097/00006534-198110000-00012
   JENSEN EC, 1959, AM J VET RES, V20, P899
   KERRIGAN CL, 1984, PLAST RECONSTR SURG, V74, P522, DOI 10.1097/00006534-198410000-00010
   Landau AG, 2008, ANN PLAS SURG, V60, P661, DOI 10.1097/SAP.0b013e318146c288
   Llanos S, 2006, ANN SURG, V244, P700, DOI 10.1097/01.sla.0000217745.56657.e5
   MCKEEVER PJ, 1978, AM J VET RES, V39, P1706, DOI 10.2460/ajvr.1978.39.10.1706
   MILLER CW, 1990, VET CLIN N AM-SMALL, V20, P189, DOI 10.1016/S0195-5616(90)50010-8
   Moisidis E, 2004, PLAST RECONSTR SURG, V114, P917, DOI 10.1097/01.PRS.0000133168.57199.E1
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Most D, 2001, PLAST RECONSTR SURG, V108, P1251, DOI 10.1097/00006534-200110000-00024
   PAVLETIC M. M., 2010, ATLAS SMALL ANIMAL W
   POPE ER, 1990, VET CLIN N AM-SMALL, V20, P177, DOI 10.1016/S0195-5616(90)50009-1
   POPE ER, 1988, COMP CONT EDUC PRACT, V10, P915
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Stanley BJ, 2013, VET SURG, V42, P511, DOI 10.1111/j.1532-950X.2013.12005.x
   SWAIM SF, 1990, VET CLIN N AM-SMALL, V20, P47, DOI 10.1016/S0195-5616(90)50003-0
   Swaim SF, 1980, SURG TRAUMATIZED SKI
   TAVIS MJ, 1976, ANN SURG, V184, P594, DOI 10.1097/00000658-197611000-00010
   Tong T, 2012, J SMALL ANIM PRACT, V53, P520, DOI 10.1111/j.1748-5827.2012.01250.x
   Weston C, 2010, ACTA CHIR BELG, V110, P19, DOI 10.1080/00015458.2010.11680559
NR 38
TC 8
Z9 10
U1 0
U2 13
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0195-5616
EI 1878-1306
J9 VET CLIN N AM-SMALL
JI Vet. Clin. N. Am.-Small Anim. Pract.
PD NOV
PY 2017
VL 47
IS 6
BP 1249
EP +
DI 10.1016/j.cvsm.2017.06.009
PG 15
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA FM1GJ
UT WOS:000414721900010
PM 28802984
DA 2026-07-24
ER

PT J
AU Davis, KG
   Johnson, EK
AF Davis, Kurt G.
   Johnson, Eric K.
TI Controversies in the Care of the Enterocutaneous Fistula
SO SURGICAL CLINICS OF NORTH AMERICA
LA English
DT Article
DE Enterocutaneous fistula; Enteroatmospheric fistula; Abdominal wall
   reconstruction; Complications
ID VACUUM-ASSISTED CLOSURE; ABDOMINAL-WALL DEFECTS; COMPONENTS SEPARATION
   TECHNIQUE; TOTAL PARENTERAL-NUTRITION; TRIAL COMPARING
   POLYGLACTIN-910-MESH; GASTROINTESTINAL-CUTANEOUS FISTULAS; ACELLULAR
   DERMAL MATRIX; MASSIVE VENTRAL HERNIAS; OPEN ABDOMEN; CROHNS-DISEASE
AB Enterocutaneous fistula and its variations are some of the most difficult problems encountered in the practice of general surgery. Reliable evidence that can be used to direct the care of patients afflicted with this malady is limited. There are controversies in several areas of care. This article addresses some of the gray areas of care for the patient with enterocutaneous fistula. There is particular attention directed toward the phenomenon of enteroatmospheric fistula, as well as prevention and abdominal wall reconstruction, which is often required in these individuals.
C1 [Davis, Kurt G.] William Beaumont Army Med Ctr, Dept Surg, Sect Colon & Rectal Surg, El Paso, TX 79920 USA.
   [Johnson, Eric K.] Joint Base Lewis McChord, Madigan Army Med Ctr, Dept Surg, Sect Colon & Rectal Surg, Tacoma, WA 98431 USA.
C3 William Beaumont Army Medical Center; Madigan Army Medical Center
RP Johnson, EK (通讯作者)，JBLM, Dept Surg, Sect Gen Surg, Tacoma, WA 98431 USA.
EM doktrj@gmail.com
RI /AAD-9885-2020
CR Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
   AGUIRRE A, 1974, ANN SURG, V180, P393, DOI 10.1097/00000658-197410000-00003
   Al-Khoury G, 2008, J AM COLL SURGEONS, V206, P397, DOI 10.1016/j.jamcollsurg.2007.07.027
   BARNES SM, 1993, INT J PANCREATOL, V14, P181
   Becker HP, 2007, SCAND J SURG, V96, P263, DOI 10.1177/145749690709600402
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   Berry S M, 1994, Curr Probl Surg, V31, P469
   Björck M, 2011, AM SURGEON, V77, pS58
   Blatnik J, 2008, AM J SURG, V196, P47, DOI 10.1016/j.amjsurg.2007.06.035
   Campos ACL, 1999, J AM COLL SURGEONS, V188, P483, DOI 10.1016/S1072-7515(99)00038-1
   Carbonell AM, 2008, HERNIA, V12, P359, DOI 10.1007/s10029-008-0356-2
   CHAPMAN R, 1964, AM J SURG, V108, P157, DOI 10.1016/0002-9610(64)90005-4
   Chaudhry Rajan, 2004, Med J Armed Forces India, V60, P235, DOI 10.1016/S0377-1237(04)80053-4
   Collier B, 2007, JPEN-PARENTER ENTER, V31, P410, DOI 10.1177/0148607107031005410
   Cox-Reijven PLM, 2003, AM J CLIN NUTR, V78, P1111, DOI 10.1093/ajcn/78.6.1111
   Cro C, 2002, POSTGRAD MED J, V78, P364, DOI 10.1136/pmj.78.920.364
   Dayton M, 2006, SURGERY, V140, P576
   de Moya MA, 2008, J TRAUMA, V65, P349, DOI 10.1097/TA.0b013e31817fb782
   DICOSTANZO J, 1987, JPEN-PARENTER ENTER, V11, P465, DOI 10.1177/0148607187011005465
   Dionigi G, 2008, Int J Surg, V6, P51, DOI 10.1016/j.ijsu.2007.07.006
   Dragu A, 2009, WORLD J SURG, V33, P1174, DOI 10.1007/s00268-009-9991-8
   Draus JM, 2006, SURGERY, V140, P570, DOI 10.1016/j.surg.2006.07.003
   Dubose Joseph J, 2010, Clin Colon Rectal Surg, V23, P182, DOI 10.1055/s-0030-1262986
   Dudrick SJ, 1999, WORLD J SURG, V23, P570, DOI 10.1007/PL00012349
   EDMUNDS LH, 1960, ANN SURG, V152, P445
   EMORY RE, 1992, ARCH SURG-CHICAGO, V127, P1365
   Ennis LS, 2003, AM SURGEON, V69, P733
   Erdmann D, 2001, PLAST RECONSTR SURG, V108, P2066, DOI 10.1097/00006534-200112000-00036
   Evenson AR, 2006, J GASTROINTEST SURG, V10, P455, DOI 10.1016/j.gassur.2005.08.001
   Ewart CJ, 2003, ANN PLAS SURG, V50, P269, DOI 10.1097/01.SAP.0000046911.07345.0D
   Fabian TC, 2007, SURG CLIN N AM, V87, P73, DOI 10.1016/j.suc.2006.09.011
   Fazio VW., 1996, INTESTINAL FISTULA A, P363
   Fischer JE, 2008, AM J SURG, V196, P1, DOI 10.1016/j.amjsurg.2008.01.001
   GEOGHEGAN J, 1990, BRIT J CLIN PRACT, V44, P750
   Girard S, 2002, AM J SURG, V184, P166, DOI 10.1016/S0002-9610(02)00916-9
   Goverman J, 2006, J TRAUMA, V60, P428, DOI 10.1097/01.ta.0000203588.66012.c4
   Hadad I, 2009, AM SURGEON, V75, P301
   HANAUER SB, 1993, AM J GASTROENTEROL, V88, P646
   Harris C, 2008, J WOUND OSTOMY CONT, V35, P169, DOI 10.1097/01.WON.0000313639.37247.c0
   HEDDERICH GS, 1986, SURGERY, V99, P399
   Hernandez-Aranda J C, 1996, Nutr Hosp, V11, P226
   Hesse U, 2001, GUT, V49, pIV11, DOI 10.1136/gut.49.suppl_4.iv11
   HILD P, 1986, LANCET, V2, P626
   Howdieshell TR, 2004, AM J SURG, V188, P301, DOI 10.1016/j.amjsurg.2004.03.007
   Hwang, 2000, Curr Surg, V57, P443, DOI 10.1016/S0149-7944(00)00319-6
   Jamshidi R, 2007, ARCH SURG-CHICAGO, V142, P793, DOI 10.1001/archsurg.142.8.793
   JENKINS SA, 1995, EUR J GASTROEN HEPAT, V7, P255
   Jernigan TW, 2003, ANN SURG, V238, P349, DOI 10.1097/01.sla.0000086544.42647.84
   Joels CS, 2006, SURG INNOV, V13, P223, DOI 10.1177/1553350606296922
   Kafie FE, 2003, AM SURGEON, V69, P102
   Kingsnorth AN, 2008, WORLD J SURG, V32, P26, DOI 10.1007/s00268-007-9287-9
   KORELITZ BI, 1985, DIGEST DIS SCI, V30, P58, DOI 10.1007/BF01318372
   Koss W, 2009, J SURG EDUC, V66, P89, DOI 10.1016/j.jsurg.2008.12.003
   Kritayakirana Kritaya, 2010, J Emerg Trauma Shock, V3, P118, DOI 10.4103/0974-2700.62106
   KUVSHINOFF BW, 1993, ANN SURG, V217, P615, DOI 10.1097/00000658-199306000-00003
   Kuvshinoff BW, 1993, ANN SURG, V217, P22
   Layton Brian, 2010, Am J Surg, V199, pe48, DOI 10.1016/j.amjsurg.2009.06.028
   LEVY E, 1989, BRIT J SURG, V76, P676, DOI 10.1002/bjs.1800760708
   Lowe JB III, 2003, PLAST RECONSTR SURG, V111, P1276, DOI 10.1097/01.PRS.0000047021.36879.FD
   Lundy Jonathan B, 2010, Clin Colon Rectal Surg, V23, P133, DOI 10.1055/s-0030-1262980
   Lynch AC, 2004, ANN SURG, V240, P825, DOI 10.1097/01.sla.0000143895.17811.e3
   Maas SM, 1999, J AM COLL SURGEONS, V189, P138, DOI 10.1016/S1072-7515(99)00067-8
   Makhdoom ZA, 2000, J CLIN GASTROENTEROL, V31, P195, DOI 10.1097/00004836-200010000-00003
   Martinez JL, 2008, WORLD J SURG, V32, P436, DOI 10.1007/s00268-007-9304-z
   Memon Abdul Sattar, 2004, J Coll Physicians Surg Pak, V14, P25
   Milburn Meghan L, 2007, Hernia, V11, P157, DOI 10.1007/s10029-006-0175-2
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   O'Brien B, 1998, Ostomy Wound Manage, V44, P20
   PEDERZOLI P, 1986, SURG GYNECOL OBSTET, V163, P428
   Polk TM, 2012, WORLD J SURG, V36, P524, DOI 10.1007/s00268-011-1315-0
   Present DH, 1999, NEW ENGL J MED, V340, P1398, DOI 10.1056/NEJM199905063401804
   Prichayudh S, 2011, SURG TODAY, V41, P72, DOI 10.1007/s00595-009-4202-7
   RAMIREZ OM, 1990, PLAST RECONSTR SURG, V86, P519, DOI 10.1097/00006534-199009000-00023
   Ramsay PT, 2010, AM SURGEON, V76, P637
   Rao M, 2007, COLORECTAL DIS, V9, P266, DOI 10.1111/j.1463-1318.2006.01154.x
   REBER HA, 1978, ANN SURG, V188, P460, DOI 10.1097/00000658-197810000-00003
   Reilingh TSD, 2007, WORLD J SURG, V31, P756, DOI 10.1007/s00268-006-0502-x
   Reilingh TSD, 2003, J AM COLL SURGEONS, V196, P32, DOI 10.1016/S1072-7515(02)01478-3
   Rodriguez ED, 2007, PLAST RECONSTR SURG, V120, P669, DOI 10.1097/01.prs.0000270303.44219.76
   Rosen M J, 2007, Hernia, V11, P435, DOI 10.1007/s10029-007-0255-y
   Rosen MJ, 2007, AM J SURG, V194, P385, DOI 10.1016/j.amjsurg.2007.03.003
   SANCHO JJ, 1995, BRIT J SURG, V82, P638, DOI 10.1002/bjs.1800820521
   Satya R, 2010, J VASC INTERV RADIOL, V21, P414, DOI 10.1016/j.jvir.2009.11.015
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   Schecter WP, 2011, SURG CLIN N AM, V91, P481, DOI 10.1016/j.suc.2011.02.004
   Schecter WP, 2009, J AM COLL SURGEONS, V209, P484, DOI 10.1016/j.jamcollsurg.2009.05.025
   Scott BG, 2006, J TRAUMA, V60, P17, DOI 10.1097/01.ta.0000200861.96568.bb
   Sepehripour S, 2010, MINERVA CHIR, V65, P577
   Shabatian H, 2008, AM SURGEON, V74, P912
   Shaikh IA, 2010, COLORECTAL DIS, V12, P931, DOI 10.1111/j.1463-1318.2009.01929.x
   SHEPPARD M, 1979, J CLIN ENDOCR METAB, V48, P50, DOI 10.1210/jcem-48-1-50
   SITGESSERRA A, 1982, BRIT J SURG, V69, P147, DOI 10.1002/bjs.1800690310
   SOETERS PB, 1979, ANN SURG, V190, P189, DOI 10.1097/00000658-197908000-00012
   Stark B, 2007, Hernia, V11, P533, DOI 10.1007/s10029-007-0235-2
   Stevens P, 2009, INT WOUND J, V6, P259, DOI 10.1111/j.1742-481X.2009.00614.x
   Subramaniam MH, 2002, J TRAUMA, V53, P386, DOI 10.1097/00005373-200208000-00037
   Tinkoff G, 2008, J TRAUMA, V65, P342
   Tobias AM, 2003, PLAST RECONSTR SURG, V112, P766, DOI 10.1097/01.PRS.0000070175.10990.51
   TORRES AJ, 1992, ARCH SURG-CHICAGO, V127, P97
   Vargo D, 2004, AM J SURG, V188, P633, DOI 10.1016/j.amjsurg.2004.08.051
   Vertrees A, 2008, J AM COLL SURGEONS, V207, P801, DOI 10.1016/j.jamcollsurg.2008.08.014
   Viscido A, 2003, ALIMENT PHARM THER, V17, P1263, DOI 10.1046/j.1365-2036.2003.01535.x
   Wright A, 2011, OSTOMY WOUND MANAG, V57, P28
   ZERA RT, 1983, DIS COLON RECTUM, V26, P109, DOI 10.1007/BF02562587
   [No title captured]
NR 105
TC 34
Z9 42
U1 0
U2 17
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0039-6109
J9 SURG CLIN N AM
JI Surg. Clin.-North Am.
PD FEB
PY 2013
VL 93
IS 1
BP 231
EP +
DI 10.1016/j.suc.2012.09.009
PG 22
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 065JY
UT WOS:000313145800015
PM 23177074
DA 2026-07-24
ER

PT J
AU Rojas, SV
   Junghans, S
   Fox, H
   Lazouski, K
   Schramm, R
   Morshuis, M
   Gummert, JF
   Gross, J
AF Rojas, Sebastian, V
   Junghans, Simon
   Fox, Henrik
   Lazouski, Kanstantsin
   Schramm, Rene
   Morshuis, Michiel
   Gummert, Jan F.
   Gross, Justus
TI Bacteriophage-Enriched Galenic for Intrapericardial Ventricular Assist
   Device Infection
SO ANTIBIOTICS-BASEL
LA English
DT Article
DE LVAD; left ventricular assist device; infections; bacteria;
   bacteriophages; negative pressure wound therapy; NPWT
AB We report a case of severe outflow graft infection following left ventricular assist device (LVAD) implantation. A 51-year old male LVAD patient was readmitted to our hospital presenting signs of systemic infection. One year previously, LVAD implantation (HeartMate3, Abbott, Chicago, IL, USA) with concomitant patent foramen ovale closure had been performed in the context of end-stage heart failure due to dilative cardiomyopathy (INTERMACS III). The indication for LVAD-therapy was bridge-to-candidacy, since the patient did not instantly fulfill all criteria for cardiac transplantation. At admission, a PET-CT scan unveiled fluid accumulation, encircling the outflow-graft prosthesis (SUVmax 10.5) with contrast-enhancement involving the intrathoracic driveline (SUVmax 11.2). Since cardiac transplantation was not feasible, the patient underwent surgical revision. In the first step, redo sternotomy was performed with local debridement, including jet lavage. Intraoperative swabs confirmed bacterial infection with staphylococcus aureus. Following this, the patient underwent negative pressure wound therapy (NPWT) with instillation using the V.A.C. VERAFLO system (KCI-3M, San Antonio, TX, USA) for a total of 19 days. Due to the severity of infection, local bacteriophage application was performed within the wound closure. In order to concentrate phage therapy at the infection site, phages were applied using a novel semi-fluid galenic. After wound closure, the patient was discharged with an uneventful course. A control PET-CT scan 3 months after discharge showed a significant decrease in infection (outflow graft: SUVmax 7.2, intrathoracic driveline: SUVmax 3.0) correlated with contrast enhancement. Bacterial infection of intrathoracic VAD components represents a severe and potentially life-threatening complication. If cardiac transplantation is not feasible, complex wound management strategies are required. Local bacteriophage therapy might be a promising addition to already established therapeutical options. In order to improve bacteriophage retention at the wound site, application of a viscous galenic might be beneficial.
C1 [Rojas, Sebastian, V; Fox, Henrik; Lazouski, Kanstantsin; Schramm, Rene; Morshuis, Michiel; Gummert, Jan F.] Ruhr Univ Bochum, Univ Hosp, Heart & Diabet Ctr North Rhine Westphalia, Clin Thorac & Cardiovasc Surg, D-32545 Bad Oeynhausen, Germany.
   [Junghans, Simon] G Pohl Boskamp GmbH & Co KG, D-25551 Hohenlockstedt, Germany.
   [Gross, Justus] Rostock Univ, Dept Gen Visceral Vasc & Transplantat Surg, Med Ctr, D-18057 Rostock, Germany.
C3 Ruhr University Bochum; University of Rostock
RP Rojas, SV (通讯作者)，Ruhr Univ Bochum, Univ Hosp, Heart & Diabet Ctr North Rhine Westphalia, Clin Thorac & Cardiovasc Surg, D-32545 Bad Oeynhausen, Germany.
EM srojashernandez@hdz-nrw.de; s-junghans@web.de; hfox@hdz-nrw.de;
   klazouski@hdz-nrw.de; rschramm@hdz-nrw.de; mmorshuis@hdz-nrw.de;
   jgummert@hdz-nrw.de; justus.gross@med.uni-rostock.de
RI Fox, Henrik/AAG-9968-2019; Rojas, Sebastian/AFR-1536-2022
OI Fox, Henrik/0000-0002-2187-8715; Gross, Justus/0000-0002-3281-7512;
   Rojas, Sebastian/0000-0002-9505-1358; Gummert, Jan/0000-0002-6956-9110
CR Bernhardt AM, 2020, J CRIT CARE, V56, P106, DOI 10.1016/j.jcrc.2019.12.014
   Hanff TC, 2019, CURR HEART FAIL REP, V16, P168, DOI 10.1007/s11897-019-00438-x
   Krzelj K, 2022, THORAC CARDIOV SURG, V70, P493, DOI 10.1055/s-0041-1731823
   Mulzer J, 2020, EUR J CARDIO-THORAC, V57, P1003, DOI 10.1093/ejcts/ezz295
   Pienta M, 2021, JTCVS OPEN, V8, DOI 10.1016/j.xjon.2021.08.005
   Rojas SV, 2016, CURR OPIN CARDIOL, V31, P308, DOI 10.1097/HCO.0000000000000290
   Rubalskii E, 2020, ANTIBIOTICS-BASEL, V9, DOI 10.3390/antibiotics9050232
   Rubalskii E, 2019, SCI REP-UK, V9, DOI 10.1038/s41598-018-38318-4
   Shore S, 2022, J HEART LUNG TRANSPL, V41, P1, DOI 10.1016/j.healun.2021.10.006
   Tkhilaishvili T, 2022, J HEART LUNG TRANSPL, V41, P551, DOI 10.1016/j.healun.2022.01.018
   Tkhilaishvili T, 2021, J INFECTION, V83, pE1, DOI 10.1016/j.jinf.2021.05.027
   Yost G, 2021, ASAIO J, V67, P642, DOI 10.1097/MAT.0000000000001287
NR 12
TC 16
Z9 18
U1 0
U2 2
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
SN 2079-6382
J9 ANTIBIOTICS-BASEL
JI Antibiotics-Basel
PD MAY
PY 2022
VL 11
IS 5
AR 602
DI 10.3390/antibiotics11050602
PG 6
WC Infectious Diseases; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Pharmacology & Pharmacy
GA 1T6ZU
UT WOS:000804879300001
PM 35625246
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Seswandhana, MR
   Gunadi
   Anwar, SL
   Aryandono, T
   Dachlan, I
   Mulyono, B
   Widodo, I
   Wirohadidjojo, YW
   Sukma, MPL
   Adhityo, P
AF Seswandhana, Muhammad Rosadi
   Gunadi
   Anwar, Sumadi L.
   Aryandono, Teguh
   Dachlan, Ishandono
   Mulyono, Budi
   Widodo, Irianiwati
   Wirohadidjojo, Yohanes W.
   Sukma, Mokhammad P. L.
   Adhityo, Pramana
TI The role of negative pressure wound therapy on TGF-β1, MMP-9, α-SMA, and
   collagen type III in preventing burn contractures in a porcine model
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article
DE Negative pressure; wound therapy (NPWT); Wound healing; Burn management;
   Cytokines; Wound contraction
ID METALLOPROTEINASES; MECHANISM; MATRIX; INJURY
AB Introduction: Burns are a leading cause of disability and death, requiring prolonged hospitalization and high costs that impair daily activities. Wound healing involves cytokines and growth factors. Despite various treatments, ideal wound dressing remains unidentified. Negative pressure wound therapy (NPWT) has shown potential as an ideal wound healing environment. We compared saline dressings, silver sulfadiazine, intermittent NPWT, and continuous NPWTon wound contraction, re-epithelialization, and biomarkers (MMP-9, TGF-beta 1, alpha-SMA, and COL3) in a porcine deep dermal burn model. Methods: Six male Yorkshire pigs received 20 burns and were treated with NaCl 0.9% dressings, silver sulfadiazine, intermittent, or continuous NPWT. Wound healing was assessed on days 1, 3, 7, 14, and 21. MMP-9 and TGF-beta 1 were analyzed using ELISA, alpha-SMA, and COL3 using immunohistochemistry. Statistical analyses included linear regression, ANOVA, post-hoc tests, and path analyses. Results: Intermittent NPWT showed the lowest wound contraction on days 14 and 21 (p < 0.001) and highest re-epithelialization on day-21 (p=0.0027). MMP-9 and TGF-beta 1 levels were significantly elevated in both NPWT groups across most time points (days 1, 3, 7, and 14), with TGF-beta 1 peaking in the NaCl group on day-21. Significant alpha-SMA histoscores differences appeared on day 3, while COL3 differences were significant on day-14. Conclusions: NPWT may reduce wound contraction and accelerates re-epithelialization without impairing wound healing, confirmed by modulation of MMP-9, TGF beta 1, alpha-SMA, and COL3, suggesting the potential to minimize contracture scar formation. (c) 2026 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
C1 [Seswandhana, Muhammad Rosadi; Dachlan, Ishandono] Univ Gadjah Mada, Dr Sardjito Hosp, Plast Reconstruct & Aesthet Surg Div, Fac Med Publ Hlth & Nursing,Dept Surg, Jl Kesehatan 1, Yogyakarta 55281, Indonesia.
   [Gunadi] Univ Gadjah Mada, Dr Sardjito Hosp, Fac Med Publ Hlth & Nursing,Translat Res Unit, Dept Surg,Pediat Surg Div,Genet Working Grp, Yogyakarta 55281, Indonesia.
   [Anwar, Sumadi L.; Aryandono, Teguh] Univ Gadjah Mada, Dr Sardjito Hosp, Fac Med Publ Hlth & Nursing, Dept Surg,Div Surg Oncol, Yogyakarta 55281, Indonesia.
   [Mulyono, Budi] Univ Gadjah Mada, Fac Med Publ Hlth & Nursing, Clin Pathol Dept, Jl Farmako, Yogyakarta 55281, Indonesia.
   [Widodo, Irianiwati] Univ Gadjah Mada, Dr Sardjito Hosp, Fac Med Publ Hlth & Nursing, Dept Pathol, Yogyakarta 55281, Indonesia.
   [Wirohadidjojo, Yohanes W.] Univ Gadjah Mada, Dr Sardjito Gen Hosp, Fac Med Publ Hlth & Nursing, Dept Dermatol & Venereol, Yogyakarta 55281, Indonesia.
   [Sukma, Mokhammad P. L.; Adhityo, Pramana] Univ Gadjah Mada, Dr Sardjito Hosp, Fac Med Publ Hlth & Nursing, Dept Surg, Yogyakarta 55281, Indonesia.
C3 Central General Hospital Dr. Sardjito; Gadjah Mada University; Gadjah
   Mada University; Central General Hospital Dr. Sardjito; Gadjah Mada
   University; Central General Hospital Dr. Sardjito; Gadjah Mada
   University; Gadjah Mada University; Central General Hospital Dr.
   Sardjito; Gadjah Mada University; Central General Hospital Dr. Sardjito;
   Gadjah Mada University
RP Seswandhana, MR (通讯作者)，Univ Gadjah Mada, Dr Sardjito Hosp, Plast Reconstruct & Aesthet Surg Div, Fac Med Publ Hlth & Nursing,Dept Surg, Jl Kesehatan 1, Yogyakarta 55281, Indonesia.
EM rosadi_seswandhana@ugm.ac.id; drgunadi@ugm.aca; irianiwati@ugm.ac.id;
   yohanes.widodo@ugm.ac.id
RI Seswandhana, Rosadi/AAH-4064-2020
FU Academic Excellence Grant from Universitas Gadjah Mada [7725/UN1,
   P.II/Dit-Lit/PT.01.03/2023]
FX This research was funded by Academic Excellence Grant from Universitas
   Gadjah Mada (7725/UN1.P.II/Dit-Lit/PT.01.03/2023) .
CR AB A, 2017, Current Trends in Biomedical Engineering & Biosciences, V10, DOI [10.19080/ctbeb.2017.10.555785, 10.19080/CTBEB.2017.10.555785, DOI 10.19080/CTBEB.2017.10.555785, 10.19080/ctbeb.2017.10.555785]
   Abazari M, 2022, INT J LOW EXTR WOUND, V21, P18, DOI 10.1177/1534734620924857
   Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
   Anscher MS, 2010, ONCOLOGIST, V15, P350, DOI 10.1634/theoncologist.2009-S101
   Brownhill VR, 2021, ADV WOUND CARE, V10, P345, DOI 10.1089/wound.2020.1218
   Caley MP, 2015, ADV WOUND CARE, V4, P225, DOI 10.1089/wound.2014.0581
   Campaner AB, 2006, J INVEST DERMATOL, V126, P1168, DOI 10.1038/sj.jid.5700200
   Diller RB, 2022, BIOMIMETICS-BASEL, V7, DOI 10.3390/biomimetics7030087
   Dobson GP, 2024, J BURN CARE RES, V45, P1041, DOI 10.1093/jbcr/irae049
   Frear CC, 2020, BJS-BRIT J SURG, V107, P1741, DOI 10.1002/bjs.11993
   Frear CC, 2021, WOUND REPAIR REGEN, V29, P288, DOI 10.1111/wrr.12887
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Grubbs H, 2025, Wound physiology
   Guo HF, 2017, INT J BURNS TRAUMA, V7, P107
   Hamra NF, 2021, OPEN ACCESS MACED J, V9, P35, DOI [10.3889/oamjms.2021.5537, DOI 10.3889/OAMJMS.2021.5537]
   Hinz B, 2015, MATRIX BIOL, V47, P54, DOI 10.1016/j.matbio.2015.05.006
   Indonesian Ministry of Health, 2014, Report of National Basic Health Research (RISKESDAS) 2014
   Indonesian Ministry of Health, 2018, Report of National Basic Health Research (RISKESDAS) 2018
   Krejner A, 2016, CHRONIC WOUND CARE M, V3, P29, DOI 10.2147/CWCMR.S73819
   Liu CB, 2023, FRONT SURG, V10, DOI 10.3389/fsurg.2023.1040407
   Lu F, 2011, ANN PLAS SURG, V66, P296, DOI 10.1097/SAP.0b013e3181ea1e9b
   Malmsjo Malin, 2012, Eplasty, V12, pe5
   Martinez-Garcia CM, 2019, INVEST OPHTH VIS SCI, V60
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Ozgok Kangal MK, 2025, Physiology, wound healing
   Pastar I, 2014, ADV WOUND CARE, V3, P445, DOI 10.1089/wound.2013.0473
   Resadita R, 2022, ANN MED SURG, V75, DOI 10.1016/j.amsu.2022.103367
   Rowan MP, 2015, CRIT CARE, V19, DOI 10.1186/s13054-015-0961-2
   Seswandhana M R, 2023, Ann Burns Fire Disasters, V36, P222
   Seswandhana MR, 2025, BURNS, V51, DOI 10.1016/j.burns.2025.107719
   Seswandhana R, 2021, Ann Burns Fire Disasters, V34, P187
   Sharma C, 2021, INT J BURNS TRAUMA, V11, P275
   Singh Drishtant, 2023, Cardiol Cardiovasc Med, V7, P5, DOI [10.26502/fccm.92920302, 10.26502/fccm.92920302]
   Sober S A, 2024, Ann Burns Fire Disasters, V37, P330
   Stewart DC, 2025, J INVEST DERMATOL, V145, DOI 10.1016/j.jid.2024.08.013
   Sweeney IR, 2012, INT WOUND J, V9, P601, DOI 10.1111/j.1742-481X.2011.00923.x
   Valluru M, 2011, FRONT PHYSIOL, V2, DOI 10.3389/fphys.2011.00089
   Wild T, 2024, Scars, P11, DOI DOI 10.1007/978-3-031-24137-6_2
   Xiaojie W, 2022, CYTOKINE GROWTH F R, V66, P26, DOI 10.1016/j.cytogfr.2022.03.001
   Yurista G, 2024, Chinese Journal of Plastic and Reconstructive Surgery, V6, P166, DOI [10.1016/j.cjprs.2024.09.002, 10.1016/j.cjprs.2024.09.002, DOI 10.1016/J.CJPRS.2024.09.002]
   Zaver V, 2025, Negative pressure wound therapy
   Zhang YX, 2024, HELIYON, V10, DOI 10.1016/j.heliyon.2024.e37059
   Zhao WM, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0191031
NR 43
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD MAR
PY 2026
VL 114
BP 58
EP 70
DI 10.1016/j.bjps.2025.12.034
EA JAN 2026
PG 13
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CX9NT
UT WOS:001677069400001
PM 41570608
DA 2026-07-24
ER

PT J
AU Matsumoto, T
   Yasunaga, H
   Matsui, H
   Fushimi, K
   Izawa, N
   Yasui, T
   Kadono, Y
   Tanaka, S
AF Matsumoto, Takumi
   Yasunaga, Hideo
   Matsui, Hiroki
   Fushimi, Kiyohide
   Izawa, Naohiro
   Yasui, Tetsuro
   Kadono, Yuho
   Tanaka, Sakae
TI Time trends and risk factors for perioperative complications in total
   ankle arthroplasty: retrospective analysis using a national database in
   Japan
SO BMC MUSCULOSKELETAL DISORDERS
LA English
DT Article
DE Ankle arthrodesis; Ankle arthroplasty; Ankle fusion; Low-volume
   hospitals; Outcomes; Trends
ID FOLLOW-UP; REPLACEMENT; ARTHRODESIS; REGISTER; INTERMEDIATE;
   MULTICENTER; POPULATION; OUTCOMES; FUSION; VOLUME
AB Background: Total ankle arthroplasty (TAA) has become increasingly popular worldwide as an alternative to ankle arthrodesis for surgical treatment of end-stage ankle arthritis. The aim of this epidemiological study, using a national inpatient database in Japan, was to describe the volume, utilization, patient characteristics, and temporal trends regarding these procedures in Japan, and to identify the risk factors associated with perioperative adverse events in TAA.
   Methods: This was a population-based, retrospective cohort study. We retrospectively identified 2775 patients in the Diagnosis Procedure Combination database who underwent ankle arthrodesis or TAA for ankle arthritis at 559 hospitals in Japan from 2007 to 2013. Information on sex, age, main diagnosis, use of blood transfusion, duration of anesthesia, length of hospital stay, in-hospital mortality, hospitalization costs, additional procedures after primary surgery, and use of negative pressure wound therapy was extracted. Multivariable logistic regression analysis was performed to analyze the effect of various factors on the incidence of perioperative adverse events in TAA, including additional procedure during hospitalization, negative pressure wound therapy, blood transfusion, and in-hospital death.
   Results: We identified 465 patients who underwent TAA and 2310 patients who underwent ankle arthrodesis. There was no apparent increase in the proportion of TAAs performed during the survey period. Patients undergoing TAA tended to be older, female, and have rheumatoid arthritis compared with those undergoing ankle arthrodesis. Patients undergoing TAA had shorter length of stay, higher hospitalization costs, and more blood transfusions compared with those undergoing ankle arthrodesis. Lower hospital volume and shorter anesthesia time were associated with higher rates of adverse events after TAA.
   Conclusions: Despite an increase in the popularity of TAA internationally, the number of TAAs performed remains low in Japan. Lower hospital volume and anesthesia time were associated with higher rates of perioperative adverse events after TAA.
C1 [Matsumoto, Takumi; Izawa, Naohiro; Kadono, Yuho; Tanaka, Sakae] Univ Tokyo, Fac Med, Dept Orthopaed Surg, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan.
   [Yasunaga, Hideo; Matsui, Hiroki] Univ Tokyo, Sch Publ Hlth, Dept Clin Epidemiol & Hlth Econ, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan.
   [Fushimi, Kiyohide] Tokyo Med & Dent Univ, Grad Sch, Dept Hlth Policy & Informat, Bunkyo Ku, 1-5-45 Yushima, Tokyo 1130034, Japan.
   [Yasui, Tetsuro] Teikyo Univ, Mizonokuchi Hosp, Dept Orthopaed Surg, Takatsu Ku, 3-8-3 Mizonokuchi, Kawasaki, Kanagawa 2138507, Japan.
C3 University of Tokyo; University of Tokyo; Institute of Science Tokyo;
   Tokyo Medical & Dental University (TMDU); Teikyo University
RP Matsumoto, T (通讯作者)，Univ Tokyo, Fac Med, Dept Orthopaed Surg, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan.
EM matumot-tky@umin.ac.jp
RI Tanaka, Sakae/Y-3061-2019; Matsui, Hirotoshi/LJK-3566-2024;
   /AAO-2405-2020; Yasui, Tetsuro/IWU-5302-2023
OI Tanaka, Sakae/0000-0001-9210-9414; Yasunaga, Hideo/0000-0002-6017-469X; 
FU Ministry of Health, Labor and Welfare, Japan [H27-Policy-Designated-009,
   H27-Policy-Strategy-011]
FX This work was supported by grants for Research on Policy Planning and
   Evaluation from the Ministry of Health, Labor and Welfare, Japan (grant
   numbers: H27-Policy-Designated-009 and H27-Policy-Strategy-011). The
   funder has played no role in the design, data collection and analysis,
   decision to publish or preparation of the manuscript. The authors did
   not receive any other outside funding or grants in support of their
   research for or preparation of this work. Neither they nor any member of
   their immediate families received payments or other benefits or a
   commitment or agreement to provide such benefits from a commercial
   entity.
CR Argenson JN, 2013, ORTHOP TRAUMATOL-SUR, V99, P385, DOI 10.1016/j.otsr.2013.03.014
   CHARLSON ME, 1987, J CHRON DIS, V40, P373, DOI 10.1016/0021-9681(87)90171-8
   Clement R Carter, 2013, Foot Ankle Spec, V6, P263, DOI 10.1177/1938640013493463
   Daniels TR, 2014, J BONE JOINT SURG AM, V96A, P135, DOI 10.2106/JBJS.L.01597
   Gadd RJ, 2014, FOOT ANKLE INT, V35, P434, DOI 10.1177/1071100714524549
   Greene K A, 1991, J Arthroplasty, V6, P321, DOI 10.1016/S0883-5403(06)80183-X
   Haskell A, 2004, FOOT ANKLE INT, V25, P283, DOI 10.1177/107110070402500502
   Henricson A., 2014, FUSS SPRUNGGELENK, V12, P65
   Henricson A, 2007, ACTA ORTHOP, V78, P569, DOI 10.1080/17453670710014248
   Jameson SS, 2014, J ARTHROPLASTY, V29, P1889, DOI 10.1016/j.arth.2014.05.019
   Jiang JJ, 2015, FOOT ANKLE INT, V36, P360, DOI 10.1177/1071100714558511
   Jones RE, 2013, BONE JOINT J, V95B, P144, DOI 10.1302/0301-620X.95B11.32836
   Kessler B, 2012, J BONE JOINT SURG AM, V94A, P1871, DOI 10.2106/JBJS.K.00593
   Kostuj T, 2014, Z ORTHOP UNFALLCHIR, V152, P446, DOI 10.1055/s-0034-1382933
   Lampley A, 2016, FOOT ANKLE INT
   Lee KB, 2008, FOOT ANKLE INT, V29, P978, DOI 10.3113/FAI.2008.0978
   Myerson MS, 2003, FOOT ANKLE INT, V24, P17, DOI 10.1177/107110070302400102
   Noelle S, 2013, INT ORTHOP, V37, P1789, DOI 10.1007/s00264-013-1971-9
   Nunley JA, 2012, J BONE JOINT SURG AM, V94A, P43, DOI 10.2106/JBJS.J.01613
   OECD iLibrary, HLTH GLANC 2015
   Pinar N, 2012, ORTHOP TRAUMATOL-SUR, V98, pS26, DOI 10.1016/j.otsr.2012.04.004
   Pugely AJ, 2014, FOOT ANKLE INT, V35, P207, DOI 10.1177/1071100713511606
   Quan HD, 2005, MED CARE, V43, P1130, DOI 10.1097/01.mlr.0000182534.19832.83
   Raikin SM, 2014, FOOT ANKLE INT, V35, P216, DOI 10.1177/1071100713517101
   Raikin SM, 2010, J BONE JOINT SURG AM, V92A, P2150, DOI 10.2106/JBJS.I.00870
   Reuver JM, 2010, FOOT ANKLE INT, V31, P1064, DOI 10.3113/FAI.2010.1064
   Roukis TS, 2013, J FOOT ANKLE SURG, V52, P728, DOI 10.1053/j.jfas.2013.08.006
   Saltzman CL, 2009, FOOT ANKLE INT, V30, P579, DOI 10.3113/FAI.2009.0579
   Singh JA, 2016, CLIN RHEUMATOL, V35, P239, DOI 10.1007/s10067-014-2703-2
   Skyttä ET, 2010, ACTA ORTHOP, V81, P114, DOI 10.3109/17453671003685459
   SooHoo NF, 2007, J BONE JOINT SURG AM, V89A, P2143, DOI 10.2106/JBJS.F.01611
   Werner BC, 2015, FOOT ANKLE INT, V36, P863, DOI 10.1177/1071100715576569
   Whalen JL, 2010, FOOT ANKLE INT, V31, P301, DOI 10.3113/FAI.2010.0301
   Zaidi R, 2013, BONE JOINT J, V95B, P1500, DOI 10.1302/0301-620X.95B11.31633
NR 34
TC 25
Z9 25
U1 0
U2 3
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1471-2474
J9 BMC MUSCULOSKEL DIS
JI BMC Musculoskelet. Disord.
PD OCT 28
PY 2016
VL 17
AR 450
DI 10.1186/s12891-016-1299-x
PG 8
WC Orthopedics; Rheumatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Rheumatology
GA EM1AT
UT WOS:000395051100003
PM 27793137
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Li, XG
   Yang, Z
   Du, CZ
   Deng, LL
   Ran, JJ
   Ran, JL
   Huang, PC
   Rui, SL
   Guo, L
   Deng, WQ
AF Li, Xiaogang
   Yang, Zhou
   Du, Chenzhen
   Deng, Liling
   Ran, Junjie
   Ran, Junlin
   Huang, Pengcheng
   Rui, Shunli
   Guo, Lian
   Deng, Wuquan
TI A Portable, Mechanically Driven Negative Pressure Wound Therapy System
   Promotes Healing via Piezo1 Mechanotransduction
SO DERMATOLOGIC THERAPY
LA English
DT Article
DE constant force spring; negative pressure wound therapy; Piezo1 channel;
   portable medical device
ID MULTICENTER; CARE
AB BackgroundNegative pressure wound therapy (NPWT) aids wound healing but typically requires bulky electric pumps, restricting its use in resource-limited areas. This article describes the creation of a portable, mechanically driven NPWT system (PMNPWT) to address this issue and to investigate the underlying molecular mechanisms of its therapeutic effects.MethodsThe PMNPWT device was engineered to deliver a stable, continuous negative pressure of -125 mmHg. Its therapeutic efficacy was evaluated in a rat full-thickness excisional wound model. To identify molecular drivers, an integrated transcriptomic analysis intersected the GEO dataset, mechanosensitive gene databases, and our RNA-seq data (Sham vs. NPWT). The causal role of Piezo1 was validated in vivo through pharmacological modulation with the inhibitor GsMT & times; 4 or the agonist Yoda1 under PMNPWT treatment, and further corroborated in vitro using 3T3 fibroblast assays to assess migration, proliferation, and survival.ResultsThe PMNPWT system maintained a stable negative pressure at -125 mmHg with minimal fluctuation. Activated PMNPWT significantly accelerated wound closure, reaching 89% by Day 10 (compared with 74% in the Sham group and 64% in the NC group), increased collagen deposition by 3.59-fold, and elevated microvessel density by 3.4-fold. Transcriptomic profiling revealed a robust upregulation of Piezo1, with an 8.7-fold increase in mRNA and a 2.1-fold increase in protein expression. Pharmacological inhibition of Piezo1 with GsMT & times; 4 reduced wound closure to 46%, whereas its activation via Yoda1 enhanced closure to 96%. In vitro, Piezo1 activation promoted fibroblast migration (2.5-fold) and survival while concurrently suppressing apoptosis.ConclusionsThe PMNPWT system accelerates wound healing through Piezo1-mediated mechanotransduction, providing a stable, portable, and power-independent alternative to conventional NPWT devices. These findings establish a mechanobiological foundation supporting its potential application in clinical and resource-limited settings.
C1 [Li, Xiaogang; Yang, Zhou; Du, Chenzhen; Deng, Liling; Ran, Junjie; Ran, Junlin; Huang, Pengcheng; Rui, Shunli; Deng, Wuquan] Chongqing Univ, Cent Hosp, Dept Diabetic Foot Med Res Ctr, Dept Endocrinol,Sch Med, Chongqing 400014, Peoples R China.
   [Guo, Lian] Chongqing Univ, Dept Chongqing Univ Three Gorges Hosp, Chongqing, Peoples R China.
   [Deng, Wuquan] Kings Coll London, Dept Sch Life Course & Populat Hlth Sci, London WC2R 2LS, England.
C3 Chongqing University; Chongqing University; University of London; King's
   College London
RP Rui, SL; Deng, WQ (通讯作者)，Chongqing Univ, Cent Hosp, Dept Diabetic Foot Med Res Ctr, Dept Endocrinol,Sch Med, Chongqing 400014, Peoples R China.; Guo, L (通讯作者)，Chongqing Univ, Dept Chongqing Univ Three Gorges Hosp, Chongqing, Peoples R China.; Deng, WQ (通讯作者)，Kings Coll London, Dept Sch Life Course & Populat Hlth Sci, London WC2R 2LS, England.
EM 0243701014@stu.cqu.edu.cn; lianguo@cqu.edu.cn; wuquandeng@cqu.edu.cn
FU National Key Clinical Specialties [GJZDZK202201]; Noncommunicable
   Chronic Diseases-National Science and Technology Major Project
   [2023ZD0509400, 02]; National Natural Science Foundation of China
   [82370903]; Chongqing Municipal Education Commission [KJZD-M202400102]
FX The authors are grateful to the Gene Expression Omnibus (GEO) database
   for providing the mRNA expression datasets used in this study.
CR Agha R, 2025, Premier Journal of Science, DOI [10.70389/pjs.100082, 10.70389/PJS.100082, DOI 10.70389/PJS.100082]
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Arundel C, 2025, LANCET, V405, P1689, DOI 10.1016/S0140-6736(25)00143-6
   Ashima, 2023, 2023 IEEE International Symposium on Medical Measurements and Applications (MeMeA), P1, DOI 10.1109/MeMeA57477.2023.10171870
   Atcha H, 2021, NAT COMMUN, V12, DOI 10.1038/s41467-021-23482-5
   Berglund B., 1999, GUIDELINES COMMUNITY
   Chavali P, 2025, International Surgery Journal, V12, P968, DOI [10.18203/2349-2902.isj20251537, 10.18203/2349-2902.isj20251537, DOI 10.18203/2349-2902.ISJ20251537]
   Chen P, 2024, DIABETES-METAB RES, V40, DOI 10.1002/dmrr.3644
   Chen P, 2021, CELL CALCIUM, V97, DOI 10.1016/j.ceca.2021.102431
   Deng LL, 2025, RESEARCH-CHINA, V8, DOI 10.34133/research.0702
   Deng W, 2016, J WOUND CARE, V25, P393, DOI 10.12968/jowc.2016.25.7.393
   Elhage KG, 2022, HEALTH SCI REP-US, V5, DOI 10.1002/hsr2.425
   Fong KD, 2012, ADV WOUND CARE, V1, P41, DOI 10.1089/wound.2011.0281
   Galiano RD, 2004, WOUND REPAIR REGEN, V12, P485, DOI 10.1111/j.1067-1927.2004.12404.x
   Gefen A, 2023, INT WOUND J, V20, P1960, DOI 10.1111/iwj.14056
   Grimstad O, 2022, DERMATOL THER, V35, DOI 10.1111/dth.15483
   Hill PW, 2019, INT C REHAB ROBOT, P311, DOI 10.1109/ICORR.2019.8779422
   Hope JM, 2022, BMC BIOL, V20, DOI 10.1186/s12915-022-01266-7
   Humphrey JD, 2014, NAT REV MOL CELL BIO, V15, P802, DOI 10.1038/nrm3896
   Kilkenny C, 2010, PLOS BIOL, V8, DOI 10.1371/journal.pbio.1000412
   Lee KS, 2018, FRONT NEUROROBOTICS, V12, DOI 10.3389/fnbot.2018.00038
   MacLean MK, 2020, J MED DEVICES, V14, DOI 10.1115/1.4047996
   Miyamoto T, 2014, J BIOL CHEM, V289, P16565, DOI 10.1074/jbc.M113.528638
   Ning J, 2025, REGEN THER, V30, P371, DOI 10.1016/j.reth.2025.06.014
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Orlov A, 2023, INT WOUND J, V20, P328, DOI 10.1111/iwj.13879
   Panayi AC, 2017, World Journal of Dermatology, V6, P1, DOI [10.5314/wjd.v6.i1.1, 10.5314/wjd.v6.i1.1, DOI 10.5314/WJD.V6.I1.1]
   Physician A. A. G. P. M. B. W., VOHRA
   Shankaran V, 2013, DERMATOL THER, V26, P215, DOI 10.1111/dth.12050
   Shin SJ, 2014, J CRANIOFAC SURG, V25, P1427, DOI 10.1097/SCS.0000000000000575
   Sogorski A, 2018, J TISSUE VIABILITY, V27, P267, DOI 10.1016/j.jtv.2018.08.004
   Sugimoto A, 2023, BIOCHEM BIOPH RES CO, V682, P39, DOI 10.1016/j.bbrc.2023.09.080
   Swoboda Laura, 2021, Wounds, V33, pE85, DOI 10.25270/wnds/2021.e85e89
   Tang XY, 2022, MICROMACHINES-BASEL, V13, DOI 10.3390/mi13060900
   Teot L., 2024, J WOUND MANAGEMENT, V25
   Tuuli MG, 2020, JAMA-J AM MED ASSOC, V324, P1180, DOI 10.1001/jama.2020.13361
   Wang JY, 2025, TRENDS PHARMACOL SCI, V46, P752, DOI 10.1016/j.tips.2025.06.009
   Wang Y, 2024, SCI ADV, V10, DOI [10.1126/sciadv.adn3289, 10.1126/sciadv.adj3289]
   Xing H, 2025, FRONT IMMUNOL, V16, DOI 10.3389/fimmu.2025.1600194
   Xue YC, 2025, NAT COMMUN, V16, DOI 10.1038/s41467-025-62270-3
   Zeybek B, 2021, MED ENG PHYS, V98, P104, DOI 10.1016/j.medengphy.2021.11.003
   Zhang XM, 2022, THERANOSTICS, V12, P1621, DOI 10.7150/thno.64963
   Zurovcik D., DEV SIMPLIFIED NEGAT, P91
   Zurovcik Danielle R, 2015, J Orthop Trauma, V29 Suppl 10, pS33, DOI [10.1097/bot.0000000000000410, 10.1097/BOT.0000000000000410]
NR 45
TC 0
Z9 0
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1396-0296
EI 1529-8019
J9 DERMATOL THER
JI Dermatol. Ther.
PY 2026
VL 2026
IS 1
AR 6191163
DI 10.1155/dth/6191163
PG 17
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA KZ3IT
UT WOS:001819179000001
DA 2026-07-24
ER

PT J
AU Gillespie, BM
   Thalib, L
   Ellwood, D
   Kang, E
   Mahomed, K
   Kumar, S
   Chaboyer, W
AF Gillespie, B. M.
   Thalib, L.
   Ellwood, D.
   Kang, E.
   Mahomed, K.
   Kumar, S.
   Chaboyer, W.
TI Effect of negative-pressure wound therapy on wound complications in
   obese women after caesarean birth: a systematic review and meta-analysis
SO BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
LA English
DT Review
DE Caesarean section; high-risk wound; surgery; surgical site infection;
   vacuum therapy; wound complication; wound dressing
ID SURGICAL-SITE INFECTION; CLOSED INCISION MANAGEMENT; DELIVERY; IMPACT;
   PREVENTION; SURGERY; TRIAL; RISK
AB Background Obesity is associated with increased surgical-site infection (SSI) following caesarean section (CS). Objective To summarise the evidence on the effectiveness of negative-pressure wound therapy (NPWT) for preventing SSI and other wound complications in obese women after CS. Search strategy MEDLINE, Embase, CINAHL, Cochrane CENTRAL databases and were systematically searched in March 2021. Selection criteria Randomised controlled trials (RCTs) of NPWT compared with standard dressings after CS birth. Data collection and analysis Pooled effect sizes were calculated using either fixed or random effects models based on heterogeneity. The Cochrane risk of bias and Grading of Recommendations Assessment, Development and Evaluation tools were used to assess the quality of studies and overall quality of evidence. Main results Ten RCTs with 5583 patients were included; studies were published between 2012 and 2021. Nine RCTs with 5529 patients were pooled for the outcome SSI. Meta-analysis results suggest a significant difference favouring the NPWT group (relative risk [RR] 0.79, 95% CI 0.65-0.95, P < 0.01), indicating an absolute risk reduction of 1.8% among those receiving NPWT compared with usual care. The risk of blistering in the NPWT group was significantly higher (RR 4.13, 95% CI 1.53-11.18, P = 0.005). All studies had high risk of bias relative to blinding of personnel/participants. Only 40% of studies reported blinding of outcome assessments and 50% had incomplete outcome data. Conclusions The decision to use NPWT should be considered both in terms of its potential benefits and its limitations. Tweetable abstract NPWT was associated with fewer SSI in women following CS birth but was not effective in reducing other wound complications.
C1 [Gillespie, B. M.; Chaboyer, W.] Griffith Univ, Natl Hlth & Med Res Council Ctr Res Excellence Wi, Menzies Hlth Inst, Gold Coast, Qld, Australia.
   [Gillespie, B. M.; Chaboyer, W.] Gold Coast Hosp & Hlth Serv, Gold Coast, Qld, Australia.
   [Thalib, L.] Istanbul Aydin Univ, Fac Med, Dept Biostat, Istanbul, Turkey.
   [Ellwood, D.] Griffith Univ, Sch Med & Dent, Gold Coast, Qld, Australia.
   [Ellwood, D.] Gold Coast Univ Hosp, Gold Coast, Qld, Australia.
   [Kang, E.] Griffith Univ, Menzies Hlth Inst, Gold Coast, Qld, Australia.
   [Mahomed, K.] Ipswich Hosp, Ipswich, Qld, Australia.
   [Kumar, S.] Univ Queensland, Mater Res Inst, Brisbane, Qld, Australia.
   [Kumar, S.] Mater Mothers Hosp, South Brisbane, Qld, Australia.
C3 Griffith University; Menzies Health Institute Queensland; Gold Coast
   University Hospital; Istanbul Aydin University; Griffith University;
   Gold Coast University Hospital; Menzies Health Institute Queensland;
   Griffith University; University of Queensland; Mater Research; Mater
   Health Services; Mater Mothers' Hospital
RP Gillespie, BM (通讯作者)，Griffith Univ, NHMRC Wiser Wounds CRE, MHIQ, Gold Coast, Qld 4215, Australia.
EM b.gillespie@griffith.edu.au
RI Mahomed, Kassam/M-1335-2013; Gillespie, Brigid/E-7799-2012; Thalib,
   Lukman/HAI-7553-2022; Ellwood, David/C-8208-2015; Chaboyer,
   Wendy/F-9588-2018
OI Thalib, Lukman/0000-0002-1211-6495; Kang, Evelyn/0000-0001-8253-1638;
   Ellwood, David/0000-0003-4512-6443; Chaboyer, Wendy/0000-0001-9528-7814
CR [Anonymous], 2020, REV MANAGER REVMAN C
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Boerma T, 2018, LANCET, V392, P1341, DOI 10.1016/S0140-6736(18)31928-7
   Chaboyer W, 2014, HEALTHCARE, V2, P417, DOI 10.3390/healthcare2040417
   Deeks J., 2008, COCHRANE HDB SYSTEMA, P243, DOI [10.1002/9780470712184, DOI 10.1002/9780470712184]
   Gillespie BM, 2021, BMJ-BRIT MED J, V373, DOI 10.1136/bmj.n893
   Gillespie BM, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0203354
   Gillespie BM, 2015, SURG INNOV, V22, P488, DOI 10.1177/1553350615573583
   Gunatilake RP, 2017, AJP REP, V7, pE151, DOI 10.1055/s-0037-1603956
   Guyatt G., 2008, USERS GUIDES MEDICAL
   Guyatt GH, 2008, BMJ-BRIT MED J, V336, P924, DOI 10.1136/bmj.39489.470347.AD
   Heslehurst N, 2008, OBES REV, V9, P635, DOI 10.1111/j.1467-789X.2008.00511.x
   Higgins JPTTJ., 2021, COCHRANE HDB SYSTEMA
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   Huang HP, 2021, J MATERN-FETAL NEO M, V34, P2498, DOI 10.1080/14767058.2019.1668924
   Hussamy DJ, 2019, OBSTET GYNECOL, V134, P781, DOI 10.1097/AOG.0000000000003465
   Hyldig N, 2019, BJOG-INT J OBSTET GY, V126, P628, DOI 10.1111/1471-0528.15413
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Maehara Y, 2017, SURG TODAY, V47, P1060, DOI 10.1007/s00595-017-1480-3
   Malmsjo Malin, 2014, Eplasty, V14, pe15
   Moher D, 2010, INT J SURG, V8, P658, DOI 10.1016/j.ijsu.2010.07.299
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Ruhstaller K, 2017, AM J PERINAT, V34, P1125, DOI 10.1055/s-0037-1604161
   Scott IA, 2010, ARCH INTERN MED, V170, P387
   Smid MC, 2017, OBSTET GYNECOL, V130, P969, DOI 10.1097/AOG.0000000000002259
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   StataCorp, 2019, STATA STAT SOFTWARE
   Stitely M., 2013, PREVENTION WOUND COM
   Tuuli MG, 2020, JAMA-J AM MED ASSOC, V324, P1180, DOI 10.1001/jama.2020.13361
   Tuuli MG, 2017, AM J OBSTET GYNECOL, V216, pS245, DOI 10.1016/j.ajog.2016.11.670
   Webster J., 2019, COCHRANE DB SYST REV, V3, P170
   Webster J, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub3
   Whittemore R, 2005, J ADV NURS, V52, P546, DOI 10.1111/j.1365-2648.2005.03621.x
   Wihbey KA, 2018, OBSTET GYNECOL, V132, P377, DOI [10.1097/AOG.0000000000002744, 10.1097/aog.0000000000002744]
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Yu LL, 2018, AM J OBSTET GYNECOL, V218, P200, DOI 10.1016/j.ajog.2017.09.017
   Zuarez-Easton S, 2017, INT J WOMENS HEALTH, V9, P81, DOI 10.2147/IJWH.S98876
NR 39
TC 10
Z9 12
U1 0
U2 8
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1470-0328
EI 1471-0528
J9 BJOG-INT J OBSTET GY
JI BJOG
PD JAN
PY 2022
VL 129
IS 2
BP 196
EP 207
DI 10.1111/1471-0528.16963
EA NOV 2021
PG 12
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA XP8SR
UT WOS:000715865700001
PM 34622545
DA 2026-07-24
ER

PT J
AU Fernández-de-Velasco, D
   Carnero-Alcázar, M
   Reguillo-Lacruz, FJ
   Torrón, JMM
   Villamor-Jiménez, C
   Calleja-Sanz, J
   Ruiz-Alvarez, P
   Maroto-Castellanos, L
   Moores, S
   Alvarez-de-Arcaya, MA
AF Fernandez-de-Velasco, David
   Carnero-Alcazar, Manuel
   Reguillo-Lacruz, Fernando-Jose
   Torron, Juan-Miguel Miranda
   Villamor-Jimenez, Cristina
   Calleja-Sanz, Jorge
   Ruiz-Alvarez, Pilar
   Maroto-Castellanos, Luis
   Moores, Sally
   Alvarez-de-Arcaya, Maria Arantzazu
TI Multi-Disciplinary and Protocol-Driven Post-Operative Care Reduces
   Incidence of Post-Sternotomy Mediastinitis
SO SURGICAL INFECTIONS
LA English
DT Review; Early Access
DE cardiac procedure; multidisciplinary care; negative pressure wound
   therapy; outpatient follow-up; post-sternotomy mediastinitis; sternotomy
ID INFECTIONS; THERAPY; SURVEILLANCE
AB Background: Post-sternotomy mediastinitis (PSM) is a rare but life-threatening complication of cardiac surgical procedures. This study evaluated the impact of a structured multi-disciplinary post-discharge care bundle on PSM incidence. Methods: A single-center, retrospective cohort study compared the incidence of PSM two years before and after implementation of a care bundle led by a multi-disciplinary team. The intervention included telephonic monitoring, a specialized wound-care clinic, and a standardized two-phase wound management protocol incorporating single-use negative pressure wound therapy. Outcomes were assessed using chi-square tests and logistic regression adjusted with propensity scores and inverse probability weighting. To rule out a temporal trend in newly identified wound infections, we performed a linear regression using bimonthly incident counts as the outcome. Results: A total of 1,197 patients underwent median sternotomy between May 1, 2018, and April 30, 2022. The crude incidence of PSM was 3.32% in the pre-implementation group and 1.56% in the post-implementation group (p = 0.058). After adjustment with inverse probability of treatment weighting, the care bundle was associated with a significant reduction in PSM rate (absolute risk difference 1.96%, 95% confidence interval [CI]: 0.54-3.87; p = 0.044; relative reduction 59%, 95% CI: 16.3%-116%), despite a higher baseline surgical risk in the post-implementation cohort (higher EuroSCORE II, more urgent procedures, greater need for vasoactive support). The rate of newly identified wound infections did not exhibit a significant time trend (beta = -0.43; p = 0.299). Conclusion: Implementation of a multi-disciplinary care bundle is significantly associated with a reduction in PSM incidence in cardiac sternotomy patients, underscoring the importance of structured outpatient wound surveillance.
C1 [Fernandez-de-Velasco, David; Villamor-Jimenez, Cristina] Hosp Univ Alcorcon, Dept Internal Med, C Budapest 1, Madrid 28922, Spain.
   [Carnero-Alcazar, Manuel; Reguillo-Lacruz, Fernando-Jose; Torron, Juan-Miguel Miranda; Ruiz-Alvarez, Pilar; Maroto-Castellanos, Luis] Hosp Clin Univ San Carlos, Dept Cardiac Surg, Madrid, Spain.
   [Calleja-Sanz, Jorge; Alvarez-de-Arcaya, Maria Arantzazu] Univ Complutense Madrid, Hosp Univ Clin San Carlos, Div Hosp Med, Dept Med, Madrid, Spain.
   [Moores, Sally] Smith & Nephew, Global Clin Strategy, Kingston Upon Hull, England.
C3 Alcorcon Foundation University Hospital; Complutense University of
   Madrid; Smith & Nephew
RP Fernández-de-Velasco, D (通讯作者)，Hosp Univ Alcorcon, Dept Internal Med, C Budapest 1, Madrid 28922, Spain.
EM dfernandezv@salud.madrid.org
RI Carnero, Manuel/AAF-4073-2021; Maroto, Luis/IUO-4884-2023; Álvarez-de
   Arcaya, Arántzazu/OUH-3896-2025
OI Álvarez-de Arcaya Vicente, Arántzazu/0000-0001-8998-5851
CR Bitkover CY, 1998, ANN THORAC SURG, V65, P36, DOI 10.1016/S0003-4975(97)01003-5
   Bouza E, 2021, J CLIN MED, V10, DOI 10.3390/jcm10235566
   Braxton JH, 2000, ANN THORAC SURG, V70, P2004, DOI 10.1016/S0003-4975(00)01814-2
   Calderwood MS, 2023, INFECT CONT HOSP EP, V44, P695, DOI 10.1017/ice.2023.67
   De Feo M, 2011, TEX HEART I J, V38, P375
   Doreen H., 2024, J WOUND MANAG, V25
   Eklund AM, 2006, ANN THORAC SURG, V82, P1784, DOI 10.1016/j.athoracsur.2006.05.097
   Fernández-de-Velasco D, 2022, SURG INFECT, V23, P873, DOI 10.1089/sur.2022.176
   Goh SSC, 2017, J CARDIAC SURG, V32, P556, DOI 10.1111/jocs.13189
   Graf K, 2010, EUR J CARDIO-THORAC, V37, P893, DOI 10.1016/j.ejcts.2009.10.005
   Horan TC, 2008, AM J INFECT CONTROL, V36, P309, DOI 10.1016/j.ajic.2008.03.002
   Kirsner RS, 2021, WOUND REPAIR REGEN, V29, P908, DOI 10.1111/wrr.12966
   Loubani M, 2024, INT WOUND J, V21, DOI 10.1111/iwj.14599
   MANIAN FA, 1993, INFECT CONT HOSP EP, V14, P216
   Pastene B, 2020, CLIN MICROBIOL INFEC, V26, P26, DOI 10.1016/j.cmi.2019.07.005
   Petzina R, 2010, EUR J CARDIO-THORAC, V38, P110, DOI 10.1016/j.ejcts.2010.01.028
   Rogers LJ., 2024, COCHRANE DB SYST REV, V2024, pCd013332
   Saunders C, 2021, BJS OPEN, V5, DOI 10.1093/bjsopen/zraa003
   Schaper NC, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3266
   Scott NM, 2022, HEART LUNG, V55, P89, DOI 10.1016/j.hrtlng.2022.04.013
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Tabley A, 2020, ANN THORAC SURG, V110, P2034, DOI 10.1016/j.athoracsur.2020.03.087
   US CFDCC, 2025, SURG SITE INFECT EVE
   van Wingerden JJ, 2014, J CARDIOTHORAC SURG, V9, DOI 10.1186/s13019-014-0179-4
   Witt-Majchrzak Anna, 2015, Pol Przegl Chir, V86, P456, DOI [10.2478/pjs-2014-0082, 10.2478/pjs-2014-0082]
NR 25
TC 0
Z9 0
U1 0
U2 0
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD 2026 MAR 4
PY 2026
DI 10.1177/10962964261428654
EA MAR 2026
PG 7
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA EQ2OQ
UT WOS:001707151400001
PM 41781336
DA 2026-07-24
ER

PT J
AU Marra, C
   Pentangelo, P
   Losco, L
   Ceccaroni, A
   Barbato, A
   Alfano, C
AF Marra, Caterina
   Pentangelo, Paola
   Losco, Luigi
   Ceccaroni, Alessandra
   Barbato, Alfonso
   Alfano, Carmine
TI Lower Extremity Trauma: A Multidimensional Reconstructive Approach with
   Hyperbaric Oxygen Therapy
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE lower limb trauma; soft tissue defect; lower extremity reconstruction;
   split thickness skin graft; acellular dermal matrix; ADM; negative
   pressure wound therapy; NPWT; hyperbaric oxygen therapy; HBOT
ID PRESSURE WOUND THERAPY; PLASTIC-SURGERY; MANAGEMENT; INFECTION; DEFECTS;
   SALVAGE
AB Background: Distal lower extremity reconstruction is challenging. This study aims to propose a protocol for the treatment of traumatic soft tissue defects. The key concept is to combine the surgical armamentarium of the reconstructive surgeon with the advantages provided by hyperbaric oxygen therapy. Methods: This retrospective study analyzed data of 57 patients affected with unilateral or bilateral lower extremity trauma distal to the knee and involving soft tissues with no indication of immediate reconstruction between 2010 and 2021. Before the reconstructive procedure, all the patients underwent a stick swab procedure for the collection of microbiological samples and debridement. Patients were divided into two treatment groups and only one group underwent a combined therapeutic procedure with hyperbaric oxygen therapy. Negative pressure wound therapy (NPWT) was employed only if deemed necessary according to the defect's depth and wound exudate. Surgical techniques, outcomes, and complications were discussed. Results: All patients achieved a complete recovery with no major complications and only minor complications observed. The study group treated with HBOT had a lower complication rate and lower percentages of minimal and partial graft loss compared with the same complications observed in the control group. No patients experienced HBOT-related complications. Significant reductions in the time to complete healing and the time from reconstruction to healing were found (p = 0.002 and p < 0.00001, respectively). Conclusions: A lower complication rate was observed in the group treated with HBOT. The administration of HBOT prior to soft tissue reconstruction significantly reduced the time to complete healing and the time interval from skin grafting to healing. However, prospective studies and randomized trials with larger cohorts should be designed to investigate the efficacy of HBOT for the treatment of lower extremity injuries with extensive soft tissue defects.
C1 [Marra, Caterina; Pentangelo, Paola; Losco, Luigi; Ceccaroni, Alessandra; Alfano, Carmine] Univ Salerno, Dept Med Surg & Dent, Plast Surg Unit, I-84081 Baronissi, SA, Italy.
   [Barbato, Alfonso] Azienda Osped Univ OO RR San Giovanni di Dio e Rug, Plast Surg Unit, I-84131 Salerno, SA, Italy.
C3 University of Salerno
RP Losco, L (通讯作者)，Univ Salerno, Dept Med Surg & Dent, Plast Surg Unit, I-84081 Baronissi, SA, Italy.
EM camarra@unisa.it; ppentangelo@unisa.it; llosco@unisa.it
RI ; Ceccaroni, Alessandra/JCO-7296-2023; Losco, Luigi/AAC-3499-2020
OI marra, caterina/0009-0004-8826-7830; Pentangelo,
   Paola/0000-0002-9067-4177
CR Alfano C, 2006, Acta Chirurgiae Plasticae, V48, P12
   Attia A, 2020, JPRAS OPEN, V24, P32, DOI 10.1016/j.jpra.2020.03.004
   ATTINGER C, 1995, ORTHOP CLIN N AM, V26, P295
   Bassetto F, 2019, G CHIR, V40, P257
   Bowersox J.C., 1986, J HYPERB MED, V1, P141
   Cigna E, 2021, MICROSURG, V41, P574, DOI 10.1002/micr.30753
   de Sire A, 2022, J HAND THER, V35, P605, DOI 10.1016/j.jht.2021.04.011
   Di Taranto G, 2020, J SURG ONCOL, V121, P168, DOI 10.1002/jso.25581
   Dougherty JE, 2013, CRIT CARE NURS Q, V36, P299, DOI 10.1097/CNQ.0b013e318294ea41
   FRANCEL TJ, 1992, CLIN PLAST SURG, V19, P871
   Friedman HIF, 2006, PLAST RECONSTR SURG, V117, p175S, DOI 10.1097/01.prs.0000222555.84962.86
   Gallo G, 2023, FRONT SURG, V9, DOI 10.3389/fsurg.2022.1115653
   Gentileschi S, 2020, EJSO-EUR J SURG ONC, V46, P1194, DOI 10.1016/j.ejso.2020.04.048
   GOTTLIEB LJ, 1994, PLAST RECONSTR SURG, V93, P1503, DOI 10.1097/00006534-199406000-00027
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   Hogsberg T, 2011, PLOS ONE, V6, DOI 10.1371/journal.pone.0020492
   Hom DB, 2003, LARYNGOSCOPE, V113, P1566, DOI 10.1097/00005537-200309000-00029
   Hou ZY, 2011, J TRAUMA, V71, P1705, DOI 10.1097/TA.0b013e31822e2823
   Jain K.K., 2009, Textbook of Hyperbaric Medicine, V5th
   Kakagia DD, 2023, INT J LOW EXTR WOUND, V22, P56, DOI 10.1177/1534734621990311
   Kozak GM, 2020, PLAST RECONSTR SURG, V145, p608E, DOI 10.1097/PRS.0000000000006589
   Kremer T, 2006, PLAST RECONSTR SURG, V118, P443, DOI 10.1097/01.prs.0000227742.66799.74
   Losco L, 2022, PRS-GLOB OPEN, V10, DOI 10.1097/GOX.0000000000004131
   Märdian S, 2014, ACTA CHIR ORTHOP TR, V81, P9
   Maini A., 2020, Textbook of Adult Emergency Medicine, Vfifth, P101
   Mansueto G, 2021, HEALTHCARE-BASEL, V9, DOI 10.3390/healthcare9121641
   Maruccia M, 2020, ANN PLAS SURG, V85, P56, DOI 10.1097/SAP.0000000000002259
   Menn ZK, 2012, J RECONSTR MICROSURG, V28, P139, DOI 10.1055/s-0031-1289167
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   PATZAKIS MJ, 1989, CLIN ORTHOP RELAT R, P36
   PERRINS DJD, 1967, LANCET, V1, P868
   Piotr S, 2018, POL J SURG, V90, P5, DOI 10.5604/01.3001.0011.7453
   Riccio M, 2005, MICROSURG, V25, P272, DOI 10.1002/micr.20132
   Roje Z, 2008, CROAT MED J, V49, P224, DOI 10.3325/cmj.2008.2.224
   Russo R, 2022, J CLIN MED, V11, DOI 10.3390/jcm11092518
   Soltanian H, 2015, PLAST RECONSTR SURG, V136, p815E, DOI 10.1097/PRS.0000000000001807
   Ünal S, 2005, ANN PLAS SURG, V55, P102, DOI 10.1097/01.sap.0000164531.23770.60
   Wallner B, 2023, EUR J TRAUMA EMERG S, V49, P551, DOI 10.1007/s00068-022-02107-6
   Weaver L., 2014, Hyperbaric Oxygen Therapy Indications, V13th
   Zaver V., 2023, StatPearls [Internet]
   Zeiderman MR, 2021, BURNS TRAUMA, V9, DOI 10.1093/burnst/tkab024
   Zhou DZ, 2023, MEDICINA-LITHUANIA, V59, DOI 10.3390/medicina59040762
NR 42
TC 7
Z9 9
U1 0
U2 2
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD MAR
PY 2024
VL 13
IS 5
AR 1407
DI 10.3390/jcm13051407
PG 10
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA KX6L0
UT WOS:001183302900001
PM 38592225
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Suszczynska, J
   Grabala, M
   Grabala, P
AF Suszczynska, Joanna
   Grabala, Michal
   Grabala, Pawel
TI Modulation of Surgical Site Infection Risk in Spinal and Thoracic
   Surgeries Through Operative Parameters: A Narrative Review
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Review
DE surgical site infection; spinal surgery; thoracic surgery;
   negative-pressure wound therapy; antibiotic prophylaxis; risk factors
ID PRESSURE WOUND THERAPY; INTRAOPERATIVE VANCOMYCIN; POSTERIOR APPROACH;
   FUSION; COMPLICATIONS; METAANALYSIS; PREVENTION; RESECTION;
   INSTRUMENTATION; READMISSION
AB Background: Surgical site infections (SSIs) following spinal and thoracic procedures are associated with prolonged hospitalization and increased morbidity, with incidence rates of 2-15% in spinal surgery and 3-12% in thoracic procedures. Multiple patient-related and procedure-specific factors contribute to wound complications, including diabetes mellitus, obesity, smoking, extended surgical time, excessive tissue dissection, and hardware implantation. Implementing evidence-based prevention and early intervention strategies is essential in high-risk surgical cohorts. Methods: This narrative review followed searches in PubMed, Scopus, ScienceDirect, Cochrane Library, and Embase for studies published between January 2000 and October 2025. Eligible peer-reviewed articles examined SSI incidence, risk factors, or prevention strategies in adult patients undergoing thoracic or spinal surgery. Data extraction focused on operative parameters, antibiotic prophylaxis regimens, negative-pressure wound therapy (NPWT) use, and patient outcomes. Results: Evidence from found recent studies was synthesized. Key findings demonstrated that operative duration > 4 h increased SSI odds by 41% per additional hour, and blood loss > 500 mL doubled infection risk. Prophylactic NPWT reduced deep SSI rates by 50% in high-risk patients (BMI >= 35, diabetes, multilevel instrumentation). Intrawound vancomycin powder reduced deep SSIs by 50-60%, particularly in multilevel fusions. Administering prophylactic antibiotics within 30 min of incision was significantly more effective than at 60 min, with a 23% relative risk reduction. Weight-adjusted antibiotic dosing in obese patients lowered SSI rates from 5.1% to 2.9%. Conclusions: Operative parameters strongly predict SSI risk. An integrated risk- and evidence-based approach to wound management following spinal and thoracic surgeries-combining optimized antibiotic prophylaxis, risk-stratified NPWT application, and operative technique modifications-can significantly reduce SSI incidence. Successful implementation requires institutional commitment, multidisciplinary collaboration, and continuous quality improvement to optimize patient outcomes.
C1 [Suszczynska, Joanna; Grabala, Michal] Med Univ Bialystok, Clin Dept Gen & Gastroenter Surg 2, Ul M Sklodowskiej Curie 24a, PL-15276 Bialystok, Poland.
   [Grabala, Pawel] Polish Mothers Mem Hosp Res Inst, Dept Neurosurg, Rzgowska 281-289, PL-93338 Lodz, Poland.
C3 Medical University of Bialystok; Polish Mother's Memorial Hospital -
   Research Institute
RP Grabala, P (通讯作者)，Polish Mothers Mem Hosp Res Inst, Dept Neurosurg, Rzgowska 281-289, PL-93338 Lodz, Poland.
EM joanna.suszczynska@uskwb.pl; michal@grabala.pl; pgrabala@wp.pl
RI Grabala, Pawel/AAV-5125-2020
OI Grabala, Pawel/0000-0001-7059-2935
CR Abola MV, 2021, J BONE JOINT SURG AM, V103, P219, DOI 10.2106/JBJS.20.00934
   Abukhodair A, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.43614
   Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   Ahmed Hamza, 2025, Cureus, V17, pe87385, DOI 10.7759/cureus.87385
   Akiyama T, 2021, J THORAC DIS, V13, P1445, DOI 10.21037/jtd-20-2647
   Algarny S, 2023, IN VIVO, V37, P1688, DOI 10.21873/invivo.13255
   Alpantaki Kalliopi, 2025, J Long Term Eff Med Implants, V35, P47, DOI [10.1615/jlongtermeffmedimplants.2024051157, 10.1615/JLongTermEffMedImplants.2024051157]
   Amelot A, 2021, J NEUROSURG-SPINE, V35, P366, DOI 10.3171/2020.11.SPINE201891
   Anwar FN, 2023, N AM SPINE SOC J, V16, DOI 10.1016/j.xnsj.2023.100278
   Araghi K, 2026, HSS J, V22, P123, DOI 10.1177/15563316251348440
   Atesok K, 2020, GLOB SPINE J, V10, P183, DOI 10.1177/2192568218819817
   Bagga RS, 2020, SPINE DEFORM, V8, P677, DOI 10.1007/s43390-020-00099-0
   Bagherzadeh S, 2025, CLIN NEUROL NEUROSUR, V258, DOI 10.1016/j.clineuro.2025.109173
   Bakhsheshian J, 2015, WORLD NEUROSURG, V83, P816, DOI 10.1016/j.wneu.2014.12.033
   Bandiera S, 2022, CURR ONCOL, V29, P7842, DOI 10.3390/curroncol29100620
   Barbato R, 2025, ANTIBIOTICS-BASEL, V14, DOI 10.3390/antibiotics14090934
   Bates TJ, 2024, CLIN ORTHOP RELAT R, V482, P375, DOI 10.1097/CORR.0000000000002808
   Begier E, 2022, SURG INFECT, V23, P12, DOI 10.1089/sur.2021.019
   Blum S, 2019, SURG INFECT, V20, P439, DOI 10.1089/sur.2019.039
   Brigato P, 2025, MEDICINA-LITHUANIA, V61, DOI 10.3390/medicina61061046
   Chen Z, 2022, EUR SPINE J, V31, P1546, DOI 10.1007/s00586-022-07178-y
   Cheng CW, 2019, SPINE J, V19, P602, DOI 10.1016/j.spinee.2018.09.014
   Cheng KS, 2019, MEDICINE, V98, DOI 10.1097/MD.0000000000015857
   Cies JJ, 2019, J ANTIMICROB CHEMOTH, V74, P1342, DOI 10.1093/jac/dky574
   Coccolini F, 2021, WORLD J EMERG SURG, V16, DOI 10.1186/s13017-021-00375-y
   Jadresic MC, 2024, GLOB SPINE J, V14, P485, DOI 10.1177/21925682221110819
   Cole T, 2015, SPINE, V40, P1033, DOI 10.1097/BRS.0000000000000872
   Croft LD, 2015, SPINE, V40, pE112, DOI 10.1097/BRS.0000000000000693
   Cvijanovic VS, 2019, J INFECT DEV COUNTR, V13, P212, DOI 10.3855/jidc.11240
   Daher M, 2024, CLIN ORTHOP RELAT R, V482, P2212, DOI 10.1097/CORR.0000000000003179
   De la Garza-Ramos R, 2016, NEUROL RES, V38, P117, DOI 10.1080/01616412.2016.1138669
   de Tymowski C, 2025, SURGERY, V181, DOI 10.1016/j.surg.2025.109255
   Deng H, 2020, J NEUROSURG-SPINE, V32, P292, DOI 10.3171/2019.8.SPINE19479
   Deora H, 2023, NEUROL INDIA, V71, P875, DOI 10.4103/0028-3886.388107
   Draenert R, 2025, ANAESTHESIOLOGIE, V74, P627, DOI 10.1007/s00101-025-01567-w
   Dubory A, 2015, EUR SPINE J, V24, P543, DOI 10.1007/s00586-014-3523-4
   Dupree A., 2025, Langenbeck's Arch. Surg, V410, P277, DOI [10.1007/s00423-025-03865-8, DOI 10.1007/S00423-025-03865-8]
   El Zahlawy H, 2021, Ain Shams Medical Journal, V72, P153, DOI [10.21608/asmj.2021.167370, 10.21608/asmj.2021.167370, DOI 10.21608/ASMJ.2021.167370]
   Elezbawy B, 2025, EXPERT REV ANTI-INFE, V23, P1011, DOI 10.1080/14787210.2025.2569833
   Elgafy H, 2018, WORLD J ORTHOP, V9, P271, DOI 10.5312/wjo.v9.i11.271
   Elsamadicy AA, 2016, WORLD NEUROSURG, V96, P148, DOI 10.1016/j.wneu.2016.08.097
   Farshad M, 2018, SPINE J, V18, P1625, DOI 10.1016/j.spinee.2018.02.003
   Feier CVI, 2025, J CLIN MED, V14, DOI 10.3390/jcm14155191
   Finoco M, 2026, EUR SPINE J, V35, P143, DOI 10.1007/s00586-025-09056-9
   Fletcher J, 2025, J ORTHOP, V62, P66, DOI 10.1016/j.jor.2024.10.020
   Freire-Archer M, 2023, SPINE, V48, pE269, DOI 10.1097/BRS.0000000000004713
   Freystaetter K, 2021, FRONT SURG, V8, DOI 10.3389/fsurg.2021.597410
   Gande A, 2019, SPINE J, V19, P1076, DOI 10.1016/j.spinee.2019.01.002
   Garcia MM, 2023, ACTA ORTHOP, V94, P80, DOI 10.2340/17453674.2023.9409
   Gens KD, 2025, J INFECT CHEMOTHER, V31, DOI 10.1016/j.jiac.2025.102833
   Ghobrial GM, 2015, NEUROSURG FOCUS, V39, DOI 10.3171/2015.7.FOCUS15258
   Glowka P, 2024, J CLIN MED, V13, DOI 10.3390/jcm13144068
   Gonfiotti A, 2018, J THORAC DIS, V10, pS564, DOI 10.21037/jtd.2018.01.157
   Grabala P, 2016, Polish Annals of Medicine, V23, P97, DOI [10.1016/j.poamed.2016.02.004, 10.1016/j.poamed.2016.02.004, DOI 10.1016/J.POAMED.2016.02.004]
   Grabala P, 2024, J CLIN MED, V13, DOI 10.3390/jcm13164824
   Gu HW, 2025, MEDICINE, V104, DOI 10.1097/MD.0000000000044082
   Gupta VK, 2021, SPINE J, V21, P1711, DOI 10.1016/j.spinee.2021.04.005
   Han B, 2025, INT J SURG, V111, P589, DOI 10.1097/JS9.0000000000001846
   Hayakawa C., 2024, Cureus, V16, pe50793, DOI [10.7759/cureus.50793, DOI 10.7759/CUREUS.50793]
   He XQ, 2019, CLIN SPINE SURG, V32, P150, DOI 10.1097/BSD.0000000000000778
   Helenius L, 2024, BONE JOINT J, V106B, P1176, DOI 10.1302/0301-620X.106B10.BJJ-2024-0460.R1
   Herrington B.J., 2025, GLOB SPINE J, V7, p21925682251341833, DOI [10.1177/21925682251341833, DOI 10.1177/21925682251341833]
   Ho C, 2007, SPINE, V32, P2739, DOI 10.1097/BRS.0b013e31815a5a86
   Huaman Rocio J, 2025, J Spec Oper Med, V25, P66, DOI 10.55460/9X33-ZRSV
   Iarussi T, 2008, ANN THORAC SURG, V86, P1680, DOI 10.1016/j.athoracsur.2008.04.084
   Imperatori Andrea, 2006, Surg Infect (Larchmt), V7 Suppl 2, pS57
   Imperatori A, 2017, J THORAC DIS, V9, P3222, DOI 10.21037/jtd.2017.08.122
   Imtiaz H, 2024, CUREUS J MED SCIENCE, V16, DOI 10.7759/cureus.69214
   Jadresic MC, 2025, SPINE SURG RELAT RES, V9, P1, DOI [10.22603/ssrr.2024-0189, 10.22603/ssrr.2024-0189]
   Jadresic MC, 2022, SPINE J, V22, P1801, DOI 10.1016/j.spinee.2022.07.092
   Jeong JW, 2024, BMC GERIATR, V24, DOI 10.1186/s12877-024-05526-9
   Khalid Shah, 2023, J Ayub Med Coll Abbottabad, V35, P239, DOI [10.55519/jamc-02-11179, 10.55519/JAMC-02-11179]
   Khan NR, 2014, J NEUROSURG-SPINE, V21, P974, DOI 10.3171/2014.8.SPINE1445
   Kim BD, 2014, SPINE, V39, P510, DOI 10.1097/BRS.0000000000000163
   Kim Eric K, 2021, Adv Orthop, V2021, P1949877, DOI [10.1155/2021/1949877, 10.1155/2021/1949877]
   Kobayashi Y, 2020, SPINE, V45, pE148, DOI 10.1097/BRS.0000000000003226
   Kong CG, 2025, J CLIN MED, V14, DOI 10.3390/jcm14093244
   Kowalewski M, 2023, SURGERY, V174, P1102, DOI 10.1016/j.surg.2023.05.031
   Kramer DE, 2024, NEUROSURG REV, V47, DOI 10.1007/s10143-024-03083-8
   Kunakornsawat Sombat, 2019, Asian J Neurosurg, V14, P710, DOI [10.4103/ajns.ajns_294_17, 10.4103/ajns.AJNS_294_17]
   Kuvendjiska J, 2019, J CLIN MED, V8, DOI 10.3390/jcm8070978
   Lak AM, 2020, SPINE, V45, P1451, DOI 10.1097/BRS.0000000000003573
   Lambrechts MJ, 2022, WORLD NEUROSURG, V168, P258, DOI [10.1016/j.wneu.2022.09.048, 10.1016/J.WNEU.2022.09.048]
   Laursen LO, 2016, EUR J CARDIO-THORAC, V49, P870, DOI 10.1093/ejcts/ezv205
   Lazar HL, 2014, J THORAC CARDIOV SUR, V148, P1035, DOI 10.1016/j.jtcvs.2014.06.045
   Leary OP, 2025, GLOB SPINE J, V15, p143S, DOI 10.1177/21925682241237486
   Lee MJ, 2014, SPINE J, V14, P2112, DOI 10.1016/j.spinee.2013.12.026
   Lemans JVC, 2019, SPINE J, V19, P1648, DOI 10.1016/j.spinee.2019.05.592
   Li D, 2024, EUR SPINE J, V33, P4653, DOI 10.1007/s00586-024-08494-1
   Liu JL, 2022, J INT MED RES, V50, DOI 10.1177/03000605211068689
   Liu ZM, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD012653.pub2
   Luo H, 2022, EFORT OPEN REV, V7, P109, DOI 10.1530/EOR-21-0077
   Magro PL, 2021, INTERACT CARDIOV TH, V32, P452, DOI 10.1093/icvts/ivaa292
   Marion C, 2020, EUR SPINE J, V29, P1499, DOI 10.1007/s00586-020-06427-2
   Martin R., 2025, Cureus, V17, pe86148, DOI [10.7759/cureus.86148, DOI 10.7759/CUREUS.86148]
   Masarwa Rawan, 2025, Cureus, V17, pe81519, DOI [10.7759/cureus.81519, 10.7759/cureus.81519]
   Mehta AI, 2013, J BONE JOINT SURG AM, V95A, P323, DOI 10.2106/JBJS.L.00225
   Mesfin A, 2024, CUREUS J MED SCIENCE, V16, DOI 10.7759/cureus.64591
   Mok JM, 2009, SPINE, V34, P578, DOI 10.1097/BRS.0b013e31819a827c
   Mu XP, 2024, EFORT OPEN REV, V9, P1087, DOI 10.1530/EOR-24-0091
   Naylor RM, 2020, WORLD NEUROSURG, V137, pE257, DOI 10.1016/j.wneu.2020.01.152
   Ng MK, 2024, GLOB SPINE J, V14, P869, DOI 10.1177/21925682221124530
   Norman Gill, 2017, Cochrane Database Syst Rev, V10, pCD012234, DOI 10.1002/14651858.CD012234.pub2
   Nunna RS, 2022, INT J SPINE SURG, V16, P88, DOI 10.14444/8198
   Ogihara S, 2021, SCI REP-UK, V11, DOI 10.1038/s41598-021-87110-4
   Ogihara S, 2021, EUR SPINE J, V30, P1756, DOI 10.1007/s00586-020-06609-y
   Ogihara S, 2020, WORLD NEUROSURG, V134, pE524, DOI 10.1016/j.wneu.2019.10.117
   Ojo OA, 2016, NIGER J CLIN PRACT, V19, P821, DOI 10.4103/1119-3077.183237
   Olatunbosun S, 2025, SURG INFECT, V26, P331, DOI 10.1089/sur.2024.258
   Onita T, 2025, ANTIBIOTICS-BASEL, V14, DOI 10.3390/antibiotics14101008
   Patel H, 2017, SURG INFECT, V18, P461, DOI 10.1089/sur.2016.186
   Peppard WJ, 2017, SURG INFECT, V18, P485, DOI 10.1089/sur.2016.182
   Peterson MB, 2020, ANESTH ANALG, V130, P1435, DOI 10.1213/ANE.0000000000004340
   Piantoni L, 2020, SPINE DEFORM, V8, P669, DOI 10.1007/s43390-020-00092-7
   Pivazyan G, 2023, J NEUROSURG-SPINE, V38, P585, DOI 10.3171/2022.12.SPINE221218
   Pomares PF, 2025, GLOB SPINE J, V15, P1890, DOI 10.1177/21925682241270097
   Potter BK, 2018, CLIN ORTHOP RELAT R, V476, P2325, DOI 10.1097/CORR.0000000000000521
   Price JP, 2018, CLIN SPINE SURG, V31, pE121, DOI 10.1097/BSD.0000000000000581
   Prokopienko Marek, 2024, Surg Neurol Int, V15, P402, DOI [10.25259/sni_821_2023, 10.25259/SNI_821_2023]
   Qin C., 2025, J. Cardiothorac. Vasc. Anesth, V39, P3163, DOI [10.1053/j.jvca.2025.06.056, DOI 10.1053/J.JVCA.2025.06.056]
   Ren SW, 2025, J ORTHOP SURG RES, V20, DOI 10.1186/s13018-025-05463-2
   Riedlinger D, 2025, BIOMARKERS, V30, P97, DOI 10.1080/1354750X.2025.2451950
   Rybaczek M, 2025, LIFE-BASEL, V15, DOI 10.3390/life15101615
   Saccomanno FR, 2022, SURG INFECT, V23, P332, DOI 10.1089/sur.2021.295
   Said T, 2025, CLIN SPINE SURG, V38, P427, DOI [10.1097/bsd.0000000000001936, 10.1097/BSD.0000000000001936]
   Salvetti David J, 2015, Surg Neurol Int, V6, pS500, DOI [10.4103/2152-7806.166893, 10.4103/2152-7806.166893]
   Sathish M, 2021, GLOB SPINE J, V11, P774, DOI 10.1177/2192568220937286
   Schär RT, 2025, TRIALS, V26, DOI 10.1186/s13063-025-09095-z
   Sebastian A, 2016, SPINE J, V16, P504, DOI 10.1016/j.spinee.2015.12.009
   Shan S, 2020, J INT MED RES, V48, DOI 10.1177/0300060520920057
   Shen JX, 2014, J NEUROSURG-SPINE, V21, P648, DOI 10.3171/2014.6.SPINE13636
   Shlobin NA, 2021, SPINE, V46, P624, DOI 10.1097/BRS.0000000000003904
   Shu L, 2023, WORLD NEUROSURG, V171, pE542, DOI 10.1016/j.wneu.2022.12.066
   Spatenkova V, 2021, J ORTHOP SURG RES, V16, DOI 10.1186/s13018-021-02418-1
   Subramanian MP, 2019, ANN THORAC SURG, V108, P1648, DOI 10.1016/j.athoracsur.2019.06.049
   Sullivan BT, 2019, J BONE JOINT SURG AM, V101, P2219, DOI 10.2106/JBJS.19.00425
   Sun YF, 2025, J NEUROSURG-SPINE, V43, P509, DOI 10.3171/2025.3.SPINE2547
   Sweet FA, 2011, SPINE, V36, P2084, DOI 10.1097/BRS.0b013e3181ff2cb1
   Takahashi H, 2025, INFECT DIS THER, V14, P421, DOI 10.1007/s40121-024-01095-x
   Tan T, 2020, SPINE J, V20, P435, DOI 10.1016/j.spinee.2019.09.013
   ter Gunne AFP, 2012, SPINE, V37, P2017, DOI 10.1097/BRS.0b013e31825bfca8
   Tohmasi S, 2025, SURG ENDOSC, V39, P8607, DOI 10.1007/s00464-025-12244-9
   Toi M, 2025, SURG INFECT, V26, P584, DOI 10.1089/sur.2025.007
   Tomov M, 2015, SPINE, V40, P491, DOI 10.1097/BRS.0000000000000789
   Torres KA, 2022, BMC MUSCULOSKEL DIS, V23, DOI 10.1186/s12891-022-05763-2
   Tsantes AG, 2020, J HOSP INFECT, V104, P111, DOI 10.1016/j.jhin.2019.09.015
   VANDERSALM TJ, 1989, J THORAC CARDIOV SUR, V98, P618
   Waheed Muhammad, 2025, Cureus, V17, pe84892, DOI 10.7759/cureus.84892
   Waltz PK, 2017, SURG INFECT, V18, P447, DOI 10.1089/sur.2017.062
   Wang JQ, 2025, BMC PULM MED, V25, DOI 10.1186/s12890-025-03589-x
   Wang YF, 2025, MEDICINE, V104, DOI 10.1097/MD.0000000000042818
   Wei J, 2024, PEDIATR INFECT DIS J, V43, P333, DOI 10.1097/INF.0000000000004218
   White AJ, 2022, ASIAN SPINE J, V16, P451
   Woldesenbet A, 2025, WORLD NEUROSURG, V194, DOI 10.1016/j.wneu.2024.123591
   Xie CX, 2024, EFORT OPEN REV, V9, P953, DOI 10.1530/EOR-23-0023
   Yamamoto EA, 2023, SPINE J, V23, P281, DOI 10.1016/j.spinee.2022.10.007
   Yang HH, 2023, EUR SPINE J, V32, P3634, DOI 10.1007/s00586-023-07876-1
   Yao R, 2018, GLOB SPINE J, V8, p5S, DOI 10.1177/2192568218799056
   Yudistira Andhika, 2022, Acta Inform Med, V30, P115, DOI [10.5455/aim.2022.30.115-120, 10.5455/aim.2022.30.115-120]
   Zale C, 2023, EUR SPINE J, V32, P4259, DOI 10.1007/s00586-023-07897-w
   Zhang X., 2025, ACS Appl. Mater. Interfaces, V17, P38859, DOI [10.1021/acsami.5c05798, DOI 10.1021/ACSAMI.5C05798]
   Zhang XX, 2022, MEDICINE, V101, DOI 10.1097/MD.0000000000028836
   Zhou JM, 2020, SPINE, V45, P208, DOI 10.1097/BRS.0000000000003218
NR 163
TC 5
Z9 5
U1 0
U2 0
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD NOV 17
PY 2025
VL 14
IS 22
AR 8124
DI 10.3390/jcm14228124
PG 44
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA H5943
UT WOS:001625702200001
PM 41303160
OA gold
DA 2026-07-24
ER

PT J
AU Mello, DF
AF Mello, Daniel Francisco
TI Dermal Regeneration Matrix in the Treatment of Acute Complex Wounds
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE acute complex wounds; artificial skin; dermal regeneration matrix; skin
   graft
ID MATRIDERM(R) 1 MM; RECONSTRUCTIVE SURGERY; NEGATIVE-PRESSURE;
   LOWER-EXTREMITIES; SKIN-GRAFT; BURNS; SUBSTITUTION; INTEGRA(R); DEFECTS
AB Introduction. Dermal regeneration matrices (DRMs) represent a significant advance in wound treatment, but their use remains limited because of high associated costs. Used correctly, DRMs help improve aesthetic and functional results of skin-grafted areas. Objective. This case series reports the use of a DRM of 1-mm and 2-mm thickness in the management of acute complex wounds. Materials and Methods. This is a retrospective analysis of a cohort of patients treated between 2015 and 2018. Complex wounds were defined as those with extensive loss of skin and subcutaneous tissue, or as those in critical areas, that required sequential and specialized treatment. Management of acute wounds involved debridement of devitalized tissue, wound bed preparation, DRM implantation, and split-thickness skin grafting (STSG). Negative pressure wound therapy (NPWT) was used in all cases preoperatively, after DRM implantation, and after STSG. Results of integration of DRM and skin grafts were subjectively evaluated. The Vancouver Scar Scale was used to evaluate results 12 months postoperatively. Results. Traumatic injuries were the most common etiology, and the extension of the treated wounds varied between 4 cm x 5 cm to 42 cm x 28 cm, in the greatest dimensions. A 2-mm-thick matrix was used in 14 cases, with skin grafting after 7 to 9 days. In 6 cases, a 1-mm-thick matrix was used, immediately followed by skin grafting. Negative pressure wound therapy was used in all cases. Dermal regeneration matrices and skin graft integration rates of almost 100% were achieved in all cases. No complications occurred. Conclusions. The results showed use of DRM and NPWT was a good reconstructive option in the management of acute complex wounds that required STSG. With proper patient selection, such treatment is an important tool in the armamentarium of reconstructive procedures.
C1 [Mello, Daniel Francisco] Hosp Rede DOr Sao Luiz, Itaim Unit, Plast Surg, Sao Paulo, Brazil.
RP Mello, DF (通讯作者)，Vivater Clin, Dr Alceu C Rodrigues St 247, BR-04244000 Sao Paulo, Brazil.
EM mello.plastica@gmail.com
CR Baryza Mary Jo, 1995, Journal of Burn Care and Rehabilitation, V16, P535, DOI 10.1097/00004630-199509000-00013
   Böttcher-Haberzeth S, 2012, PEDIATR SURG INT, V28, P171, DOI 10.1007/s00383-011-2990-5
   Chen BG, 2017, INT WOUND J, V14, P158, DOI 10.1111/iwj.12576
   Choi JY, 2014, ARCH PLAST SURG-APS, V41, P337, DOI 10.5999/aps.2014.41.4.337
   Debels H, 2015, PRS-GLOB OPEN, V3, DOI 10.1097/GOX.0000000000000219
   Goutos I, 2011, J WOUND CARE, V20, P55, DOI 10.12968/jowc.2011.20.2.55
   Haslik W, 2007, BURNS, V33, P364, DOI 10.1016/j.burns.2006.07.021
   Haslik W, 2010, J PLAST RECONSTR AES, V63, P360, DOI 10.1016/j.bjps.2008.09.026
   Hop MJ, 2014, BURNS, V40, P388, DOI 10.1016/j.burns.2013.08.025
   Hughes OB, 2016, PLAST RECONSTR SURG, V138, p138S, DOI 10.1097/PRS.0000000000002643
   Hur GY, 2014, BURNS, V40, P1497, DOI 10.1016/j.burns.2014.08.007
   Iorio ML, 2012, PLAST RECONSTR SURG, V130, p232S, DOI 10.1097/PRS.0b013e3182615703
   Kamolz LP, 2012, WOUNDS INT, V3, P35
   Lamy J, 2013, ANN CHIR PLAST ESTH, V58, P235, DOI 10.1016/j.anplas.2013.01.001
   Min JH, 2014, ARCH PLAST SURG-APS, V41, P330, DOI 10.5999/aps.2014.41.4.330
   Vana LPM, 2020, BURNS, V46, P596, DOI 10.1016/j.burns.2019.09.005
   Nicholas MN, 2016, CELL MOL LIFE SCI, V73, P3453, DOI 10.1007/s00018-016-2252-8
   Nyame TT, 2015, PLAST RECONSTR SURG, V136, P1379, DOI 10.1097/PRS.0000000000001748
   Petersen W, 2016, BURNS, V42, P1257, DOI 10.1016/j.burns.2016.03.017
   Schneider J, 2009, BURNS, V35, P51, DOI 10.1016/j.burns.2008.07.018
   van Zuijlen PPM, 2001, PLAST RECONSTR SURG, V108, P1938, DOI 10.1097/00006534-200112000-00014
   van Zuijlen PPM, 2000, PLAST RECONSTR SURG, V106, P615, DOI 10.1097/00006534-200009030-00014
NR 22
TC 0
Z9 0
U1 0
U2 1
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUN
PY 2022
VL 34
IS 6
BP 154
EP 158
DI 10.25270/wnds/2022.154158
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA F6QY9
UT WOS:000983583600003
DA 2026-07-24
ER

PT J
AU Wikkeling, M
   Mans, J
   Styche, T
AF Wikkeling, Marald
   Mans, Judith
   Styche, Timothy
TI Single use negative pressure wound therapy in vascular patients:
   clinical and economic outcomes
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE dehiscence; femoral endarterectomy; healthcare; negative pressure; NPWT;
   outcomes; prevention; outcomes; vascular; postoperative; single use;
   surgery; surgical site complication; surgical site infection; sNPWT;
   vascular; wound; wound care; wound healing
ID SURGICAL SITE INFECTION; SURGERY; PREVENTION; SYSTEM
AB Objective: Surgical site complications (SSCs) such as dehiscence and infection are a common issue within vascular surgeries and are a key concern to payers and clinicians. It is estimated that occurrence of complications in vascular surgery can increment length of stay by 9.72 days and costs by 3776 pound per episode. The objective of this research was to determine the clinical and economic impact of the prophylactic use of single use negative pressure wound therapy (sNWPT) in postoperative femoral endarterectomy incisions within a single centre in the Netherlands.
   Method: Data were extracted retrospectively from the medical notes of patients consecutively treated for femoral endarterectomy between January 2013 and December 2019 in a single centre in the Netherlands. Since August 2016, patients were treated with the sNPWT device and their data were compared with that of patients treated before the introduction of the device. Data were extracted on SSCs and associated healthcare resource use, with comparisons made between the two patient groups.
   Results: The study included a cohort of 108 patients. Data of patients treated by standard care (n=64) showed 32 (50%) patients developed complications. This reduced significantly in patients treated with the sNPWT device (n=44) of whom eight (18.2%) developed a postoperative complication (p=0.0011). Average postoperative costs per patient were _3119 for those in the standard care group and _2630 where the sNPWT device was used.
   Conclusion: sNPWT provided clinical and economic benefits over standard care in the treatment of femoral endarterectomy patients, significantly reducing rate of complication and their associated costs. Declaration of interest: TS is an employee of Smith+Nephew.
C1 [Wikkeling, Marald; Mans, Judith] Nij Smellinghe Ziekenhuis, Postbus 20200, NL-9200 DA Drachten, Netherlands.
   [Styche, Timothy] Smith Nephew, 101 Hessle Rd, Kingston Upon Hull, N Humberside, England.
C3 Smith & Nephew
RP Wikkeling, M (通讯作者)，Nij Smellinghe Ziekenhuis, Postbus 20200, NL-9200 DA Drachten, Netherlands.
EM tim.styche@smith-nephew.com
OI Wikkeling, Marald/0000-0002-0439-3345
CR Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe288, DOI 10.1016/S1473-3099(16)30402-9
   [Anonymous], 2016, CONS DOC CLOS SURG I
   Arous EJ, 2018, J VASC SURG, V67, P1618, DOI 10.1016/j.jvs.2017.12.031
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   Franklin J, 2018, J VASC NURS, V36, P8, DOI 10.1016/j.jvn.2017.09.002
   Guest JF, 2020, BMJ OPEN, V10, DOI 10.1136/bmjopen-2020-045253
   Jenks PJ, 2014, J HOSP INFECT, V86, P24, DOI 10.1016/j.jhin.2013.09.012
   Kuy S, 2014, ANN VASC SURG, V28, P53, DOI 10.1016/j.avsg.2013.08.002
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   Shanmugam VK, 2015, WOUND REPAIR REGEN, V23, P184, DOI 10.1111/wrr.12268
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Svensson-Björk R, 2021, J TISSUE VIABILITY, V30, P95, DOI 10.1016/j.jtv.2020.09.005
   Taylor EW, 2004, BJS-BRIT J SURG, V91, P105, DOI 10.1002/bjs.4365
   Totty JP, 2021, INT WOUND J, V18, P261, DOI 10.1111/iwj.13526
   Turtiainen J, 2010, SCAND J SURG, V99, P167, DOI 10.1177/145749691009900312
   Wojkowska-Mach Jadwiga, 2007, Przegl Epidemiol, V61, P683
NR 16
TC 6
Z9 6
U1 0
U2 1
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD SEP
PY 2021
VL 30
IS 9
BP 705
EP 710
DI 10.12968/jowc.2021.30.9.705
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA UY1FF
UT WOS:000701276500005
PM 34554842
DA 2026-07-24
ER

PT J
AU Helito, CP
   Sobrado, MF
   Giglio, PN
   Bonadio, MB
   Pécora, JR
   Demange, MK
   Gobbi, RG
AF Helito, Camilo Partezani
   Sobrado, Marcel Faraco
   Giglio, Pedro Nogueira
   Bonadio, Marcelo Batista
   Pecora, Jose Ricardo
   Demange, Marco Kawamura
   Gobbi, Riccardo Gomes
TI The use of negative-pressure wound therapy after total knee arthroplasty
   is effective for reducing complications and the need for reintervention
SO BMC MUSCULOSKELETAL DISORDERS
LA English
DT Article
DE Negative-pressure wound; Wound dehiscence; Knee arthroplasty; Wound
   complication; Periprosthetic joint infection
ID TOTAL HIP; FRACTURE SURGERY; REVISION HIP; PREVENTION; DRESSINGS;
   INFECTION; RISK
AB Background Wound healing complications are causal factors of prosthesis infection and poor postoperative evolution of patients after total knee arthroplasty (TKA). Negative-pressure wound therapy (NPWT) can be an option to minimize these complications. The aim of this study is to compare the complications of patients undergoing TKA who used a portable NPWT device in the immediate postoperative period with those of a control group. Methods A total of 296 patients were evaluated. Patients were divided into two groups: those who used NPWT for seven days in the postoperative period (Group 1 - prospective evaluated) and those who used conventional dressings (Group 2 - historical control group). Epidemiological data, comorbidities, local parameters related to the surgical wound and complications were evaluated. Results The groups did not differ in regard to sex, age and clinical comorbidities. Overall, 153 (51.7%) patients had at least one risk factor for wound complications. Patients who used NPWT had a lower rate of complications (28.5% vs. 45.7%,p = 0.001) and a lower rate of reintervention in the operating room (2% vs. 8.5%, p = 0.001). Patients in group 1 had a lower incidence of hyperaemia (14.7% vs. 40.2%,p = 0.01), skin necrosis (2.1% vs. 8.5%,p = 0.04) and wound dehiscence (3.1% vs 10.1%,p = 0.03). The use of NPWT was a protective factor for the presence of complications, with an odds ratio of 0.36 (95% CI 0.206-0.629). Conclusion The number of complications related to the wound after TKA is high; however, most of them are minor and have no impact on the treatment and clinical evolution of patients. The use of NPWT decreased the number of surgical wound complications, especially hyperaemia, dehiscence and necrosis, and reduced the need for reintervention.
C1 [Helito, Camilo Partezani; Sobrado, Marcel Faraco; Giglio, Pedro Nogueira; Bonadio, Marcelo Batista; Pecora, Jose Ricardo; Demange, Marco Kawamura; Gobbi, Riccardo Gomes] Univ Sao Paulo, Fac Med, Hosp Clin HCFMUSP, Grp Joelho,Inst Ortopedia & Traumatol, Rua Dr Ovidio Pires de Campos 333, BR-05403010 Sao Paulo, SP, Brazil.
   [Helito, Camilo Partezani; Sobrado, Marcel Faraco] Hosp Sirio Libanes, Sao Paulo, Brazil.
C3 Universidade de Sao Paulo; Hospital Sirio Libanes
RP Sobrado, MF (通讯作者)，Univ Sao Paulo, Fac Med, Hosp Clin HCFMUSP, Grp Joelho,Inst Ortopedia & Traumatol, Rua Dr Ovidio Pires de Campos 333, BR-05403010 Sao Paulo, SP, Brazil.; Sobrado, MF (通讯作者)，Hosp Sirio Libanes, Sao Paulo, Brazil.
EM marcelf@gmail.com
RI Partezani Helito, Camilo/X-3880-2019; Gobbi, Riccardo/C-8131-2012;
   Pécora, José Ricardo/HGD-1086-2022; Demange, Marco/D-2975-2009; Giglio,
   Pedro/A-7488-2017
OI Partezani Helito, Camilo/0000-0003-1139-2524; Gobbi,
   Riccardo/0000-0002-1715-4343; Pécora, José Ricardo/0000-0003-1621-5252;
   Demange, Marco/0000-0003-1999-9478; 
CR Adelani MA, 2014, BONE JOINT J, V96B, P619, DOI 10.1302/0301-620X.96B5.33479
   Bedard NA, 2019, J ARTHROPLASTY, V34, P385, DOI 10.1016/j.arth.2018.09.089
   Carroll K, 2014, CLIN MICROBIOL INFEC, V20, P130, DOI 10.1111/1469-0691.12209
   Conjeski JM, 2018, J ARTHROPLASTY, V33, P386, DOI [10.1016/j.arth.2017.09.018, 10.1016/j.arth.2018.01.025]
   Cooper HJ, 2018, INJURY, V49, P386, DOI 10.1016/j.injury.2017.11.010
   Cooper HJ, 2016, J ARTHROPLASTY, V31, P1047, DOI 10.1016/j.arth.2015.11.010
   Dingemans SA, 2018, INT ORTHOP, V42, P747, DOI 10.1007/s00264-018-3781-6
   Frosch Petra, 2004, Acta Orthop Belg, V70, P565
   Han HS, 2013, CLIN ORTHOP SURG, V5, P118, DOI 10.4055/cios.2013.5.2.118
   Helito CP, 2017, ACTA ORTOP BRAS, V25, P85
   Helito CP, 2014, CLINICS, V69, P735, DOI 10.6061/clinics/2014(11)05
   Jämsen E, 2010, J ARTHROPLASTY, V25, P87, DOI 10.1016/j.arth.2008.10.013
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Kim JH, 2019, J ARTHROPLASTY, V34, P2804, DOI 10.1016/j.arth.2019.06.020
   Kim JH, 2019, INJURY, V50, P1764, DOI 10.1016/j.injury.2019.04.018
   Kim MS, 2018, KNEE SURG SPORT TR A, V26, P3419, DOI 10.1007/s00167-018-4914-6
   Kremers K, 2019, J AM ASSOC NURSE PRA, V31, P337, DOI 10.1097/JXX.0000000000000159
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Manoharan V, 2016, J ARTHROPLASTY, V31, P2487, DOI 10.1016/j.arth.2016.04.016
   Miyahara HD, 2018, ACTA ORTOP BRAS, V26, P300, DOI 10.1590/1413-785220182605196038
   Newman JM, 2019, J ARTHROPLASTY, V34, P554, DOI 10.1016/j.arth.2018.11.017
   Nherera LM, 2017, WOUND REPAIR REGEN, V25, P474, DOI 10.1111/wrr.12530
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Patel VP, 2007, J BONE JOINT SURG AM, V89A, P33, DOI 10.2106/JBJS.F.00163
   Poultsides LA, 2018, INT ORTHOP, V42, P87, DOI 10.1007/s00264-017-3675-z
   Ravi B, 2014, ARTHRITIS RHEUMATOL, V66, P254, DOI 10.1002/art.38231
   Redfern RE, 2017, J ARTHROPLASTY, V32, P3333, DOI 10.1016/j.arth.2017.06.019
   Sharma G, 2017, INT ORTHOP, V41, P1295, DOI 10.1007/s00264-017-3484-4
   Simons MJ, 2017, J AM ACAD ORTHOP SUR, V25, P547, DOI 10.5435/JAAOS-D-15-00402
   Singh JA, 2015, ARTHRIT CARE RES, V67, P718, DOI 10.1002/acr.22497
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
NR 31
TC 24
Z9 28
U1 0
U2 6
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2474
J9 BMC MUSCULOSKEL DIS
JI BMC Musculoskelet. Disord.
PD JUL 25
PY 2020
VL 21
IS 1
AR 490
DI 10.1186/s12891-020-03510-z
PG 8
WC Orthopedics; Rheumatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Rheumatology
GA MU9AF
UT WOS:000555957500003
PM 32711504
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU McNichols, CHL
   Diaconu, S
   Liang, YY
   Ikheloa, E
   Kumar, S
   Kumar, S
   Nam, A
   Rasko, Y
AF McNichols, Colton H. L.
   Diaconu, Silviu
   Liang, Yuanyuan
   Ikheloa, Eseigboria
   Kumar, Shivum
   Kumar, Saahil
   Nam, Arthur
   Rasko, Yvonne
TI Outcomes of Ventral Hernia Repair With Concomitant Panniculectomy
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE panniculectomy; ventral hernia repair; complication; outcomes; high-risk
   patients; obese
ID ABDOMINAL-WALL RECONSTRUCTION; CONCURRENT PANNICULECTOMY; INCISIONAL
   HERNIA; PATIENT SELECTION; COMPLICATIONS; RISK
AB Purpose Combined ventral hernia repair and panniculectomy (VHR/PAN) is controversial, and the safety profile including anticipated complications has been questioned. We present a retrospective case series review of patients from the University of Maryland Medical Center to help surgeons counsel patients on the risks and benefits of this procedure.
   Methods A retrospective database was collected using current procedural terminology codes for VHR/PAN. The patient-specific variables that were studied include the following: sex, body mass index (BMI), smoking, diabetes, chronic obstructive pulmonary disease, cirrhosis, immunosuppression, length of operation, acute incarcerated hernias, hernia size and location, mesh size and location, pannus weight, concomitant component separation, use of negative-pressure wound therapy, intestinal violation, follow-up duration, ventral hernia working group, history of bariatric surgery, previous hernia repair, skin dehiscence, skin necrosis, chronic wound, surgical site infection, seroma, hematoma, fascial dehiscence, hernia recurrence, unplanned return to operating room, and medical complication. Both univariate and multivariate analyses were performed to determine which factors affected the complication outcomes.
   Results There were 106 patients with an average age and BMI of 53 years and 39, respectively. Fifty-eight patients (54.72%) had at least 1 surgical site occurrence. Twenty-three patients (21.70%) had at least 1 repair failure. Twenty-eight patients (26.42%) had an unplanned trip back to the operating room. Seventeen patients (16.04%) had at least 1 medical complication.
   Conclusions The risk factors associated with developing complications are higher BMI, longer operating time, larger mesh size, larger hernia size, component separation, use of biologic mesh, chronic obstructive pulmonary disease, and intestinal violation. The use of negative-pressure wound therapy decreased complication rates, and patients with a previous hernia repair seemed to benefit the most from having a combined VHR/PAN. However, when compared with previous reports of VHR alone, VHR/PAN does seem to increase wound complications and reoperation rates.
C1 [McNichols, Colton H. L.] Johns Hopkins Univ Hosp, Baltimore, MD 21287 USA.
   [McNichols, Colton H. L.; Liang, Yuanyuan; Ikheloa, Eseigboria; Kumar, Shivum; Kumar, Saahil; Rasko, Yvonne] Univ Maryland, Med Ctr, Baltimore, MD 21201 USA.
   [Diaconu, Silviu; Nam, Arthur] R Adams Cowley Shock Trauma Ctr, Baltimore, MD USA.
C3 Johns Hopkins University; Johns Hopkins Medicine; University System of
   Maryland; University of Maryland Baltimore; University System of
   Maryland; University of Maryland Baltimore
RP McNichols, CHL (通讯作者)，929 N Wolfe St,Unit 304, Baltimore, MD 21205 USA.
EM cmcnich1@jhmi.edu
CR Berry MF, 2007, AM J SURG, V194, P199, DOI 10.1016/j.amjsurg.2006.10.031
   Diamond S, 2015, AM SURGEON, V81, P955
   Espinosa-de-los-Monteros A, 2016, AESTHET PLAST SURG, V40, P387, DOI 10.1007/s00266-016-0628-7
   Fischer JP, 2014, J PLAST RECONSTR AES, V67, P1532, DOI 10.1016/j.bjps.2014.07.001
   Fischer JP, 2014, J PLAST RECONSTR AES, V67, P693, DOI 10.1016/j.bjps.2014.01.021
   Heller Lior, 2012, Semin Plast Surg, V26, P25, DOI 10.1055/s-0032-1302462
   Hughes KC, 1996, AM SURGEON, V62, P678
   Koolen PGL, 2014, PLAST RECONSTR SURG, V134, p539E, DOI 10.1097/PRS.0000000000000519
   Mazzocchi M, 2011, AM J SURG, V201, P776, DOI 10.1016/j.amjsurg.2010.04.013
   Momeni A, 2009, J PLAST RECONSTR AES, V62, P1250, DOI 10.1016/j.bjps.2008.03.043
   Ross SW, 2015, AM SURGEON, V81, P778
   Saxe A, 2008, OBES SURG, V18, P192, DOI 10.1007/s11695-007-9344-3
   Shubinets V, 2017, J PLAST RECONSTR AES, V70, P759, DOI 10.1016/j.bjps.2017.01.001
   Warren JA, 2015, AM SURGEON, V81, P764
   Willing C., 2016, INT WOUND J, P1
   Zemlyak AY, 2012, J SURG RES, V177, P387, DOI 10.1016/j.jss.2012.06.029
NR 16
TC 21
Z9 25
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD APR
PY 2018
VL 80
IS 4
BP 391
EP 394
DI 10.1097/SAP.0000000000001277
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GA0CY
UT WOS:000427981500017
PM 29309330
DA 2026-07-24
ER

PT J
AU Yamashita, Y
   Abe, Y
   Bando, M
   Mima, S
   Yamasaki, H
   Nagasaka, S
   Mineda, K
   Hashimoto, I
AF Yamashita, Yutaro
   Abe, Yoshiro
   Bando, Mayu
   Mima, Shunsuke
   Yamasaki, Hiroyuki
   Nagasaka, Shinji
   Mineda, Kazuhide
   Hashimoto, Ichiro
TI Surgical methods for reducing early wound dehiscence after
   reconstruction surgery for pressure ulcer
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE decubitus ulcer; debridement; flap; incisional negative pressure wound
   therapy; pressure ulcer; surgical site infection; wound; wound care;
   wound dehiscence; wound dressing; wound healing
ID SITE INFECTION; RISK
AB Objective: Early postoperative wound dehiscence is the most common complication of pressure ulcers (PUs). The authors previously investigated the risk factors for this complication and reported that the main cause of early wound dehiscence was surgical site infection. This study aimed to improve the surgical method to decrease early postoperative wound dehiscence. Method: Patients with PUs between 2005 and 2022 were retrospectively investigated. In the control group, the ulcer surface was stained with methylene blue and debrided using the conventional method (surgical debridement). For comparison purposes, three test groups were established. In group 1, the ulcer surface was covered with hydrofibre with ionic silver, and debridement was performed using the covered debridement method. In group 2, debridement was performed using the conventional method and postoperative incisional negative pressure wound therapy (iNPWT) on the skin flap. Group 3 underwent both the covered debridement method and iNPWT. PatientV data on: sex; age; body mass index (BMI); history of diabetes; smoking history; PU site; detection of meticillin-resistant Staphylococcus aureus in wound bacterial culture; serum albumin level; operation time; and ulcer size, were collected. Significant differences from the control group were determined for each factor. Results: A total of 60 patients underwent flap coverage (control group: 39 patients; group 1: six patients; group 2: eight patients; group 3: seven patients). There were no significant differences between the groups for each item except for albumin level and BMI. Rates of early wound dehiscence in the control group and groups 1, 2 and 3 were 15/39 (38.5%); 2/6 (33.3%; p=0.81); 2/8 (25%; p=0.47), and 0/7 (0.0%; p=0.049), respectively. Conclusion: A combination of methods may effectively reduce the incidence of early wound dehiscence. Declaration of interest: The authors have no conflicts of interest to declare.
C1 [Yamashita, Yutaro; Abe, Yoshiro; Bando, Mayu; Mima, Shunsuke; Yamasaki, Hiroyuki; Nagasaka, Shinji; Mineda, Kazuhide; Hashimoto, Ichiro] Tokushima Univ, Dept Plast & Reconstruct Surg, 2-50-1 Kuramoto-Cho, Tokushima, Tokushima 7708503, Japan.
C3 Tokushima University
RP Yamashita, Y (通讯作者)，Tokushima Univ, Dept Plast & Reconstruct Surg, 2-50-1 Kuramoto-Cho, Tokushima, Tokushima 7708503, Japan.
EM thestarstripjp@yahoo.co.jp
RI /AFK-5986-2022
CR [Anonymous], 2016, GLOBAL GUIDELINES PR
   Bamba R, 2017, PRS-GLOB OPEN, V5, DOI 10.1097/GOX.0000000000001187
   Cheng H, 2017, SURG INFECT, V18, P722, DOI 10.1089/sur.2017.089
   Dorafshar AH, 2010, J BURN CARE RES, V31, P791, DOI 10.1097/BCR.0b013e3181eed1d6
   Gowd AK, 2020, FOOT ANKLE SPEC, V13, P104, DOI 10.1177/1938640019835299
   Han CY, 2019, AM J INFECT CONTROL, V47, P1393, DOI 10.1016/j.ajic.2019.05.025
   Hsu KF, 2022, J PERS MED, V12, DOI 10.3390/jpm12020182
   Hurlow J, 2012, ADV WOUND CARE, V1, P104, DOI 10.1089/wound.2011.0286
   Hyldig N, 2019, BJOG-INT J OBSTET GY, V126, P628, DOI 10.1111/1471-0528.15413
   Keys KA, 2010, PLAST RECONSTR SURG, V125, P1725, DOI 10.1097/PRS.0b013e3181d51227
   Kuo FC, 2017, BIOMED RES INT, V2017, DOI 10.1155/2017/1262108
   Lindqvist EK, 2020, J PLAST SURG HAND SU, V54, P145, DOI 10.1080/2000656X.2020.1720700
   Ling ML, 2019, ANTIMICROB RESIST IN, V8, DOI 10.1186/s13756-019-0638-8
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   Papp AA, 2019, INT WOUND J, V16, P394, DOI 10.1111/iwj.13045
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Song YP, 2021, WOUND REPAIR REGEN, V29, P20, DOI 10.1111/wrr.12863
   Yamashita Y, 2023, J MED INVESTIG, V70, P101, DOI 10.2152/jmi.70.101
NR 19
TC 0
Z9 0
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD FEB
PY 2026
VL 35
IS 2
SU A
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA DL1UE
UT WOS:001686041500001
DA 2026-07-24
ER

PT J
AU Seternes, A
   Rekstad, LC
   Lossius, W
   Wasmuth, HH
AF Seternes, Arne
   Rekstad, Lars Cato
   Lossius, William
   Wasmuth, Hans H.
TI A method for treatment of deep and superficial enteroatmospheric
   fistulas in an open abdomen, ChimneyVAC: Ten years experience
SO WORLD JOURNAL OF SURGERY
LA English
DT Article
DE enteric leak; enteroatmospheric fistula; enterocutaneous fistula;
   negative pressure wound therapy; open abdomen
ID MANAGEMENT; CLASSIFICATION
AB BackgroundLeakage of intestinal fluid is a challenging event when it appears in an open abdomen (OA) and surgical deviation does not seem possible. Intestinal contents in the abdominal cavity maintain inflammation and drainage is there for essential. We have developed a method, ChimneyVAC, to treat both deep and superficial enteroatmospheric fistulas (EAF)AimsTo describe this innovative surgical technique and our 10-year experience.Material & MethodsThis single-center observational cohort study included all 16 consecutive patients treated with ChimneyVAC. Seven women and 9 men; median age: 47; (interquartile range [IQR]:39-63) years, 15 with a small bowel fistula and 1 with a large bowel fistula. All except of the colonic fistula were classified as a high output fistula; 14 were deep and 2 superficial. In this technique, a negative-pressure source is applied directly above the fistula opening, in addition to negative pressure wound therapy for the OA. This controls the leakage of intestinal fluid by direct drainage into a vacuum system, thereby avoiding contamination of the abdomen. A controlled enterocutaneous fistula (ECF) then forms as the traction from the ChimneyVAC brings the fistula opening to skin level.ResultsIn 14 patients, an ECF formed after a median of 42 (IQR:28-55) days and 12 (IQR:7-16) dressing changes. The median length of hospitalization was 103 (IQR:58-143) days. Two patients died of multiorgan failure and 14 initially survived.DiscussionThis study showed that 14 out of 16 patients survived the initial treatment for enteric leakage with the ChimneyVAC method. The outcome of ChimneyVAC treatment is a controlled ECF, which was then corrected after a median of six months. However, hospitalization is lengthy, the patients undergo several dressing changes and many needs additional parenteral nutrition until intestinal continuity is reestablished.ConclusionChimneyVAC is a feasible method for treatment of EAF in an OA, with favorable survival.
C1 [Seternes, Arne] Trondheim Reg & Univ Hosp, St Olavs Hosp, Dept Surg, Sect Vasc Surg, Trondheim, Norway.
   [Seternes, Arne] Norwegian Univ Sci & Technol, Dept Circulat & Med Imaging, Trondheim, Norway.
   [Seternes, Arne] Trondheim Reg & Univ Hosp, St Olavs Hosp, Norwegian Res Ctr Minimally Invas & Image Guided D, Trondheim, Norway.
   [Rekstad, Lars Cato; Lossius, William; Wasmuth, Hans H.] Trondheim Reg & Univ Hosp, St Olavs Hosp, Dept Surg, Sect Gastrointestinal Surg, Trondheim, Norway.
   [Seternes, Arne] Trondheim Reg & Univ Hosp, St Olavs Hosp, Dept Surg, Sect Vasc Surg, PB 3250, N-7006 Trondheim, Norway.
C3 Norwegian University of Science & Technology (NTNU); Norwegian
   University of Science & Technology (NTNU); Norwegian University of
   Science & Technology (NTNU); Norwegian University of Science &
   Technology (NTNU); Norwegian University of Science & Technology (NTNU)
RP Seternes, A (通讯作者)，Trondheim Reg & Univ Hosp, St Olavs Hosp, Dept Surg, Sect Vasc Surg, PB 3250, N-7006 Trondheim, Norway.
EM Arne.Seternes@ntnu.no
OI Wasmuth, Hans Henrik/0000-0002-1936-6868; Lossius,
   William/0000-0003-0569-4104
CR Björck M, 2016, SCAND J SURG, V105, P5, DOI 10.1177/1457496916631853
   Di Saverio S, 2016, LANGENBECK ARCH SURG, V401, P1, DOI 10.1007/s00423-015-1370-3
   Rekstad LC, 2013, J TRAUMA ACUTE CARE, V75, P487, DOI 10.1097/TA.0b013e3182995e6d
   Schecter WP, 2011, SURG CLIN N AM, V91, P481, DOI 10.1016/j.suc.2011.02.004
   Tavusbay C, 2015, SURG TODAY, V45, P1102, DOI 10.1007/s00595-014-1020-3
NR 5
TC 2
Z9 3
U1 0
U2 4
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD MAY
PY 2024
VL 48
IS 5
BP 1066
EP 1074
DI 10.1002/wjs.12156
EA MAR 2024
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA QM5V1
UT WOS:001189370800001
PM 38520633
OA hybrid
DA 2026-07-24
ER

PT J
AU Fan, CW
   Chen, PH
   Jhou, HJ
   Cheng, YC
AF Fan, Cheng-Wei
   Chen, Po-Huang
   Jhou, Hong-Jie
   Cheng, Yi-Chiao
TI Negative pressure wound management in perineal wound status post
   abdominoperineal resection and extralevator abdominoperineal excision: a
   meta-analysis and trial sequential analysis
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Article
DE Negative pressure wound therapy; Abdominoperineal resection and
   extralevator abdominoperineal excision
ID CROHNS-DISEASE; RECTAL-CANCER; THERAPY
AB Purpose Recent evidence-based publications disclosed that negative pressure wound therapy (NPWT) may reduce the incidence rate of surgical site infection (SSI) and length of stay (LOS) compared with conventional drainage in patient status post abdominoperineal resection (APR) and extralevator abdominoperineal excision (ELAPE). Methods Data sources: Eligible randomized controlled trials and retrospective and prospective studies published before January 2023 were retrieved from databases (Cochrane Library, PubMed, and Embase). Study selection: (a) The study involved patients undergoing ELAPE or APR with postoperative NPWT; (b) the study compared NWPT with conventional drainage and reported at least one outcome of interest (i.e., SSI); and (c) the study provided adequate information to calculate the effect estimated for meta-analysis. Interventions: We calculated the odds ratio (ORs) and mean differences (MDs) with 95% confidence intervals (CIs). Main outcome measures: The measure outcomes included surgical site infection(SSI) and length of stay (LOS). Results Eight articles, involving 547 patients, met the selection criteria. Compared to conventional drainage, NPWT was associated with a significantly lower SSI rate (fixed effect, OR 0.29; 95% CI 0.18-0.45; I-2 = 0%) in eight studies and 547 patients. Besides, NPWT was associated with a shorter LOS (fixed effect, MD - 2.00; CI - 2.60 to - 1.39; I-2 = 0%) than conventional drainage in three studies and 305 patients. In a trial sequential analysis, the cumulative number of patients in the analyses of both outcomes exceeded the required information size and surpassed the significance boundary in favor of NPWT, suggesting conclusive results. Conclusion NPWT is superior to conventional drainage in both SSI rate and LOS, and the statistical power of SSI and LOS are confirmed by trial sequential analysis.
C1 [Fan, Cheng-Wei] Tri Serv Gen Hosp, Natl Def Med Ctr, Dept Surg, Taipei, Taiwan.
   [Chen, Po-Huang] Tri Serv Gen Hosp, Natl Def Med Ctr, Dept Internal Med, Taipei, Taiwan.
   [Jhou, Hong-Jie] Changhua Christian Hosp, Dept Neurol, Changhua, Taiwan.
   [Cheng, Yi-Chiao] Tri Serv Gen Hosp, Natl Def Med Ctr, Dept Surg, Div Colon & Rectal Surg, Taipei, Taiwan.
C3 Tri-Service General Hospital; National Defense Medical University;
   National Defense Medical University; Tri-Service General Hospital;
   Changhua Christian Hospital; Tri-Service General Hospital; National
   Defense Medical University
RP Chen, PH (通讯作者)，Tri Serv Gen Hosp, Natl Def Med Ctr, Dept Internal Med, Taipei, Taiwan.; Cheng, YC (通讯作者)，Tri Serv Gen Hosp, Natl Def Med Ctr, Dept Surg, Div Colon & Rectal Surg, Taipei, Taiwan.
EM chenpohuang@hotmail.com; ndmcjoe@gmail.com
RI Jhou, Hong-Jie/AAP-9636-2020; Chen, Po-Huang/AAX-2927-2021; Cheng,
   Yi-Chiao/HPD-1659-2023
CR Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe288, DOI 10.1016/S1473-3099(16)30402-9
   Baker WL, 2009, INT J CLIN PRACT, V63, P1426, DOI 10.1111/j.1742-1241.2009.02168.x
   Barne EL, 2020, CLIN GASTROENTEROL H, V18, P1356, DOI 10.1016/j.cgh.2019.09.040
   Bullard KM, 2005, DIS COLON RECTUM, V48, P438, DOI 10.1007/s10350-004-0827-1
   Chadi SA, 2014, DIS COLON RECTUM, V57, P999, DOI 10.1097/DCR.0000000000000161
   Chen L, 2017, CHIN J GASTROINTEST, V20, DOI [10.3760/cma.j.issn.1671-0274.2017.08.020, DOI 10.3760/CMA.J.ISSN.1671-0274.2017.08.020]
   Chung A VS, 2014, DIS COLON RECTUM, V57, P306
   Guyatt G, 2011, J CLIN EPIDEMIOL, V64, P383, DOI 10.1016/j.jclinepi.2010.04.026
   Han JG, 2019, DIS COLON RECTUM, V62, P1477, DOI 10.1097/DCR.0000000000001495
   Han ZB, 2021, THER CLIN RISK MANAG, V17, P357, DOI 10.2147/TCRM.S306896
   Hanif Z, 2016, ANN MED SURG, V10, P32, DOI 10.1016/j.amsu.2016.07.016
   Hawkins AT, 2018, J GASTROINTEST SURG, V22, P1477, DOI 10.1007/s11605-018-3750-9
   Higgins JPT, 2003, BMJ-BRIT MED J, V327, P557, DOI 10.1136/bmj.327.7414.557
   Higgins JPT, 2011, BMJ-BRIT MED J, V343, DOI 10.1136/bmj.d5928
   Iheozor-Ejiofor Z, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD012522.pub2
   Kaneko T, 2021, INT WOUND J, V18, P103, DOI 10.1111/iwj.13499
   Liu T, 2018, IEEE ICCE
   Meyer J, 2021, INT J COLORECTAL DIS, V36, P19, DOI 10.1007/s00384-020-03732-6
   Miles W E, 1971, CA Cancer J Clin, V21, P361, DOI 10.3322/canjclin.21.6.361
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Orgill DP, 2011, PLAST RECONSTR SURG, V127, p105S, DOI 10.1097/PRS.0b013e318200a427
   Papp G, 2021, ACTA CHIR BELG, V121, P327, DOI 10.1080/00015458.2020.1778265
   Rather A FA, 2018, DIS COLON RECTUM, V61, P293
   Reiffel AJ, 2013, SURG INFECT, V14, P244, DOI 10.1089/sur.2011.126
   Riley RD, 2004, J CLIN EPIDEMIOL, V57, P911, DOI 10.1016/j.jclinepi.2004.01.018
   Stang A, 2010, EUR J EPIDEMIOL, V25, P603, DOI 10.1007/s10654-010-9491-z
   Stelzner S, 2011, INT J COLORECTAL DIS, V26, P1227, DOI 10.1007/s00384-011-1235-3
   Stroup DF, 2000, JAMA-J AM MED ASSOC, V283, P2008, DOI 10.1001/jama.283.15.2008
   Toh JWT, 2018, DIS COLON RECTUM, V61, P67, DOI 10.1097/DCR.0000000000000975
   van der Valk MJM, 2017, ADV WOUND CARE, V6, P425, DOI 10.1089/wound.2017.0749
   Webster J, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub4
   Wei SC, 2017, INTEST RES, V15, P285, DOI 10.5217/ir.2017.15.3.285
   Wells CI, 2019, WORLD J SURG, V43, P2779, DOI 10.1007/s00268-019-05116-6
   Wetterslev J, 2017, BMC MED RES METHODOL, V17, DOI 10.1186/s12874-017-0315-7
NR 34
TC 3
Z9 4
U1 0
U2 4
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0179-1958
EI 1432-1262
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD MAR 18
PY 2023
VL 38
IS 1
AR 73
DI 10.1007/s00384-023-04353-5
PG 10
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 9X2KW
UT WOS:000949602600001
PM 36933148
DA 2026-07-24
ER

PT J
AU Kuncewitch, MP
   Blackham, AU
   Clark, CJ
   Dodson, RM
   Russell, GB
   Levine, EA
   Shen, P
AF Kuncewitch, Michael P.
   Blackham, Aaron U.
   Clark, Clancy J.
   Dodson, Rebecca M.
   Russell, Gregory B.
   Levine, Edward A.
   Shen, Perry
TI Effect of Negative Pressure Wound Therapy on Wound Complications
   Post-Pancreatectomy
SO AMERICAN SURGEON
LA English
DT Article
ID SURGICAL-SITE INFECTIONS; INTERNATIONAL STUDY-GROUP; INCISIONAL HERNIA;
   RISK; LAPAROTOMY; HOSPITALIZATION; DEFINITION; PREVENTION; IMPACT
AB Surgical site infection (SSI) and incisional hernia are common complications after major pancreatectomy. We investigated the effects of negative pressure wound therapy (NPWT) on short-and long-term wound outcomes in patients undergoing pan-createctomy. A randomized controlled trial comparing the effect of NPWT with standard surgical dressing (SSD) on wounds was performed in 265 patients undergoing open gastrointestinal resections from 2012 to 2016. We performed a subset analysis of 73 patients who underwent pancreatectomy. Wound complications in the first 30 days and incisional hernia rates were assessed. There were 33 (45%) female patients in the study and the average BMI was 27.6. The pancreaticoduodectomy rate was 68 per cent, whereas 27 per cent of patients underwent distal or subtotal pancreatectomy, and 4 per cent total pancreatectomy. Incisional hernia rates were 32 per cent and 14 per cent between the SSD and NPWT groups, respectively (P = 0.067). In the SSD (n = 37) and NPWT (n = 36) cohorts, the superficial SSI, deep SSI, seroma, and dehiscence rates were 16 per cent and 14 per cent (P > 0.99), 5 per cent and 8 per cent (P = 0.67), 16 per cent and 11 per cent (P = 0.74), and 5 per cent and 3 per cent (P >= 0.99), respectively. After adjusting for pancreatic fistula and delayed gastric emptying, no statistically significant differences in the primary outcomes were observed. These findings were true irrespective of the type of resection performed. Short- and long-term wound complications were not improved with NPWT. We observed a trend toward decreased incisional hernia rates in patients treated with NPWT. Owing to the multifactorial nature of wound complications, it is yet to be determined which cohorts of pancreatectomy patients will benefit from NPWT.
C1 [Kuncewitch, Michael P.; Clark, Clancy J.; Dodson, Rebecca M.; Levine, Edward A.; Shen, Perry] Wake Forest Univ, Bowman Gray Sch Med, Dept Gen Surg, Sect Surg Oncol,Wake Forest Baptist Med Ctr, Winston Salem, NC USA.
   [Blackham, Aaron U.] Lehigh Valley Phys Grp, Div Surg Oncol, Allentown, PA USA.
   [Russell, Gregory B.] Wake Forest Univ, Dept Biostat, Winston Salem, NC USA.
C3 Wake Forest University; Wake Forest Baptist Medical Center; Wake Forest
   University
RP Shen, P (通讯作者)，Wake Forest Sch Med, Dept Gen Surg, Sect Surg Oncol, Watlington Hall,5th Floor, Winston Salem, NC 27157 USA.
EM pshen@wakehealth.edu
FU NCI NIH HHS [P30 CA012197] Funding Source: Medline; National Cancer
   Institute [P30CA012197] Funding Source: NIH RePORTER
CR Akahori T, 2016, AM J SURG, V211, P787, DOI 10.1016/j.amjsurg.2015.10.034
   Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   Bassi C, 2017, SURGERY, V161, P584, DOI 10.1016/j.surg.2016.11.014
   Baucom RB, 2016, ANN SURG ONCOL, V23, pS764, DOI 10.1245/s10434-016-5546-z
   Bensley RP, 2013, J AM COLL SURGEONS, V216, P1159, DOI 10.1016/j.jamcollsurg.2013.01.060
   Blackham AU, 2013, AM J SURG, V205, P647, DOI 10.1016/j.amjsurg.2012.06.007
   Borgstrom E, 2015, ANTHROPOL MED, V22, P333, DOI 10.1080/13648470.2015.1096603
   Ceppa EP, 2013, HPB, V15, P384, DOI 10.1111/j.1477-2574.2012.00604.x
   Erba P, 2011, ANN SURG, V253, P402, DOI 10.1097/SLA.0b013e31820563a8
   Itatsu K, 2014, BRIT J SURG, V101, P1439, DOI 10.1002/bjs.9600
   Kessler D, 2001, J BIOL CHEM, V276, P36575, DOI 10.1074/jbc.M101602200
   Kirkland KB, 1999, INFECT CONT HOSP EP, V20, P725, DOI 10.1086/501572
   Krpata DM, 2012, J AM COLL SURGEONS, V215, P635, DOI 10.1016/j.jamcollsurg.2012.06.412
   Lynam S, 2016, INT J GYNECOL CANCER, V26, P1525, DOI 10.1097/IGC.0000000000000792
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Okano K, 2015, BRIT J SURG, V102, P1551, DOI 10.1002/bjs.9919
   RYAN TJ, 1983, CIBA F SYMP, V100, P80
   Sanford DE, 2015, HPB, V17, P819, DOI 10.1111/hpb.12461
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Swartz MA, 2001, P NATL ACAD SCI USA, V98, P6180, DOI 10.1073/pnas.111133298
   Thompson JT, 2007, CLIN PLAST SURG, V34, P673, DOI 10.1016/j.cps.2007.07.005
   Wente MN, 2007, SURGERY, V142, P761, DOI 10.1016/j.surg.2007.05.005
   You L, 2016, PANCREAS, V45, P796, DOI 10.1097/MPA.0000000000000525
NR 27
TC 24
Z9 25
U1 0
U2 3
PU SOUTHEASTERN SURGICAL CONGRESS
PI CUMMING
PA 115 SAMARITAN DR, #200, CUMMING, GA 30040-2354 USA
SN 0003-1348
EI 1555-9823
J9 AM SURGEON
JI Am. Surg.
PD JAN
PY 2019
VL 85
IS 1
BP 1
EP 7
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HL3OQ
UT WOS:000458625800024
PM 30760337
DA 2026-07-24
ER

PT J
AU Erten, EE
   Öztorun, CI
   Ertürk, A
   Demir, S
   Bostanci, SA
   Çayhan, VS
   Yildiz, M
   Akbas, I
   Emeksiz, S
   Özlü, SG
   Nur, M
   Senel, E
AF Erten, Elif Emel
   Oztorun, Can Ihsan
   Erturk, Ahmet
   Demir, Sabri
   Bostanci, Suleyman Arif
   Cayhan, Vildan Selin
   Yildiz, Muge
   Akbas, Irem
   Emeksiz, Serhat
   Ozlu, Sare Gulfem
   Nur, Mujdem
   Senel, Emrah
TI Evaluation of critical parameters for optimizing the therapeutic
   approach in pediatric patients with compartment syndrome during the 2023
   Türkiye earthquake disaster
SO ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA &
   EMERGENCY SURGERY
LA English
DT Article
DE Compartment syndrome; pediatric trauma; earthquake; fasciotomy; crush
   injury; amputation; negative-pressure wound therapy (NPWT); hyperbaric
   oxygen therapy (HBOT); renal failure
ID ACUTE-RENAL-FAILURE; CRUSH SYNDROME; MARMARA EARTHQUAKE; INJURY;
   MORTALITY; VICTIMS
AB BACKGROUND: The 2023 T & uuml;rkiye earthquake resulted in a large number of pediatric victims with musculoskeletal trauma, many of whom developed compartment syndrome (CS) and crush-related complications. This study aimed to identify clinical and biochemical parameters associated with disease severity, renal failure, and limb loss in children affected by the disaster. METHODS: A retrospective analysis was conducted on 103 pediatric patients (0-18 years) admitted after the earthquake. Demo-graphic data, duration of entrapment, laboratory values (creatine kinase [CK], myoglobin, aspartate aminotransferase [AST], alanine aminotransferase [ALT], urea, potassium), and therapeutic interventions (fasciotomy, negative-pressure wound therapy [NPWT], hyperbaric oxygen therapy [HBOT], hemodialysis, and amputation) were evaluated. Receiver operating characteristic (ROC) analyses were used to determine cut-off values predicting adverse outcomes. RESULTS: Forty-seven patients (45.6%) developed compartment syndrome involving 68 limbs and underwent fasciotomy. Thirteen patients (12.6%) required limb amputation, and 19 (18.4%) underwent hemodialysis due to acute kidney injury. An entrapment dura-tion exceeding 8 hours (area under the curve [AUC]=0.84, p<0.001), CK>10,000 U/L, and myoglobin >4,000 ng/mL were independent predictors of renal failure, fasciotomy, and amputation. NPWT was applied in 66% and HBOT in 85% of patients with necrosis, con-tributing to an 82% limb salvage rate. No amputations occurred in patients without persistent necrosis. Three patients (2.9%) died from severe crush-related injuries and multi-organ failure. CONCLUSION: Prolonged entrapment and markedly elevated CK and myoglobin levels are reliable indicators of adverse outcomes in pediatric earthquake victims with compartment syndrome. Early recognition, timely decompression, and structured wound man-agement (NPWT and HBOT) are essential for improving survival and limb salvage when early surgical intervention is not feasible in large-scale disasters.
C1 [Erten, Elif Emel; Demir, Sabri; Cayhan, Vildan Selin; Yildiz, Muge; Akbas, Irem; Nur, Mujdem; Senel, Emrah] Univ Hlth Sci, Ankara Bilkent City Hosp, Dept Pediat Surg, Ankara, Turkiye.
   [Oztorun, Can Ihsan; Erturk, Ahmet; Bostanci, Suleyman Arif] Ankara Yildirim Beyazit Univ, Fac Med, Dept Pediat Surg, Ankara, Turkiye.
   [Emeksiz, Serhat] Ankara Yildirim Beyazit Univ, Fac Med, Dept Pediat Intens Care, Ankara, Turkiye.
   [Ozlu, Sare Gulfem] Ankara Yildirim Beyazit Univ, Fac Med, Dept Pediat Nephrol, Ankara, Turkiye.
C3 University of Health Sciences Turkey; Ankara Yildirim Beyazit
   University; Ankara Yildirim Beyazit University; Ankara Yildirim Beyazit
   University
RP Erten, EE (通讯作者)，Univ Hlth Sci, Ankara Bilkent City Hosp, Dept Pediat Surg, Ankara, Turkiye.
EM elifemelerten@hotmail.com
RI Emeksiz, Serhat/AAV-7613-2021; Demir, Sabri/Q-2538-2018; ÖZLÜ, Sare
   Gülfem/HCH-8357-2022; Bostancı, Süleyman/AAX-9009-2021; ertürk,
   ahmet/B-2369-2016; ÖZTORUN, can ihsan/AAF-1602-2019; barış akbaş,
   irem/HNP-6036-2023
CR Akbas E, 2024, INT ORTHOP, V48, P2513, DOI 10.1007/s00264-024-06280-8
   Bingol O, 2023, EUR J TRAUMA EMERG S, V49, P2515, DOI 10.1007/s00068-023-02325-6
   Erek E, 2002, NEPHROL DIAL TRANSPL, V17, P33, DOI 10.1093/ndt/17.1.33
   Ergen E, 2022, ULUS TRAVMA ACIL CER, V28, P1335, DOI 10.14744/tjtes.2021.57606
   Greaves I, 2021, Trauma care manual
   Kantarci G, 2002, AM J KIDNEY DIS, V40, P682, DOI 10.1053/ajkd.2002.35673
   Kundakci B, 2023, J ORTHOP SURG RES, V18, DOI 10.1186/s13018-023-04001-2
   Li CY, 2021, INJURY, V52, P3334, DOI 10.1016/j.injury.2021.08.030
   Long B, 2023, Am J Emerg Med, V56, P24
   Long BT, 2023, AM J EMERG MED, V69, P180, DOI 10.1016/j.ajem.2023.04.029
   Matsuoka T, 2002, J TRAUMA, V52, P33, DOI 10.1097/00005373-200201000-00008
   Mavrouli M, 2023, MICROORGANISMS, V11, DOI 10.3390/microorganisms11020419
   MICHAELSON M, 1992, WORLD J SURG, V16, P899, DOI 10.1007/BF02066989
   Oda J, 1997, J TRAUMA, V42, P470, DOI 10.1097/00005373-199703000-00015
   Onan E, 2024, ULUS TRAVMA ACIL CER, V30, P174, DOI 10.14744/tjtes.2024.20532
   Ozel M, 2024, AM J EMERG MED, V75, P148, DOI 10.1016/j.ajem.2023.10.050
   Ozturk I, 2024, J NEPHROL, V37, P2589, DOI 10.1007/s40620-024-02051-1
   Reis ND, 2005, J BONE JOINT SURG BR, V87B, P450, DOI 10.1302/0301-620X.87B4
   REIS ND, 1986, J BONE JOINT SURG AM, V68A, P414, DOI 10.2106/00004623-198668030-00015
   Sever MS, 2023, ACTA ORTHOP TRAUMATO, V57, DOI 10.5152/j.aott.2023.23147
   Sever MS, 2001, KIDNEY INT, V60, P1114, DOI 10.1046/j.1523-1755.2001.0600031114.x
   Wang KL, 2006, B SEISMOL SOC AM, V96, P757, DOI 10.1785/0120050191
   World Health Organization, 2023, External situation report no. 9
   World Health Organization, Turkiye and Syria earthquakes
   Yalin Mustafa, 2023, Medicina (Kaunas), V59, DOI 10.3390/medicina59091593
   Yeşiloğlu Ö, 2023, Cam and Sakura Medical Journal, V3, P4, DOI [10.4274/csmedj.galenos.2023.2023-9-8, 10.4274/csmedj.galenos.2023.2023-9-8, DOI 10.4274/CSMEDJ.GALENOS.2023.2023-9-8]
   Yilmaz S, 2024, DISASTER MED PUBLIC, V18, DOI 10.1017/dmp.2024.253
   Zhang L, 2012, INJURY, V43, P1470, DOI 10.1016/j.injury.2010.11.036
NR 28
TC 0
Z9 0
U1 2
U2 4
PU TURKISH ASSOC TRAUMA EMERGENCY SURGERY
PI ISTANBUL
PA KOPRULU MEHMET PASA SOC, DENIZ ABDAL MAH, DADASOGLU AP, 25-1 SEHREMINI,
   ISTANBUL, 00000, Turkiye
SN 1306-696X
EI 1307-7945
J9 ULUS TRAVMA ACIL CER
JI Ulus. Travma Acil Cerrahi Derg.
PD DEC
PY 2025
VL 31
IS 12
BP 1192
EP 1202
DI 10.14744/tjtes.2025.04808
PG 11
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA AP0BC
UT WOS:001653325800005
PM 41424420
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Dohmen, J
   Weissinger, D
   Peter, AST
   Theodorou, A
   Kalff, JC
   Stoffels, B
   Lingohr, P
   von Websky, M
AF Dohmen, J.
   Weissinger, D.
   Peter, A. S. T.
   Theodorou, A.
   Kalff, J. C.
   Stoffels, B.
   Lingohr, P.
   von Websky, M.
TI Evaluating a novel vertical traction device for early closure in open
   abdomen management: a consecutive case series
SO FRONTIERS IN SURGERY
LA English
DT Article
DE open abdomen (OA); abdominal compartment syndrome (ACS); temporary
   abdominal closure (TAC); definitive fascial closure (DFC); vertical
   traction device (VTD); negative pressure wound therapy (NPWT)
ID ABDOMINAL COMPARTMENT SYNDROME; PRESSURE WOUND THERAPY; DAMAGE-CONTROL;
   LAPAROTOMY
AB Background In emergency surgery, managing abdominal sepsis and critically ill patients with imminent abdominal compartment syndrome (ACS) using an open abdomen (OA) approach has become standard practice for damage control. To prevent significant complications associated with OA therapy, such as abdominal infections, entero-atmospheric fistula (EAF), and abdominal wall hernia formation, early definitive fascial closure (DFC) is crucial. This study aims to assess the feasibility of a novel device designed to facilitate early fascial closure in patients with an open abdomen.Methods Between 2019 and 2020, nine patients undergoing open abdomen management were enrolled in this study. All patients were treated using vertical mesh-mediated fascial traction combined with a novel vertical traction device (VTD). Data from these cases were collected and retrospectively analyzed.Results In this study, all patients were treated with OA due to impending ACS. Three patients died before achieving DFC, while the remaining six patients successfully underwent DFC. The mean number of surgical procedures after OA was 3 +/- 1, and the mean time to DFC was 9 +/- 3 days. The use of the VTD in combination with negative pressure wound therapy (NPWT) resulted in a 76% reduction in fascia-to-fascia distance until DFC was achieved. The application of the VTD did not affect ventilation parameters or the Simplified Acute Physiology Score II (SAPS II), but intra-abdominal pressure (IAP) was reduced from 31 +/- 8 mmHg prior to OA to 8.5 +/- 2 mmHg after applying the device. The primary complication associated with the device was skin irritation, with three patients developing skin blisters as the most severe manifestation.Conclusion Overall, the novel VTD appears to be a safe and feasible option for managing OA cases. It may reduce complications associated with OA by promoting early definitive fascial closure.
C1 [Dohmen, J.; Weissinger, D.; Peter, A. S. T.; Kalff, J. C.; Lingohr, P.] Univ Bonn, Dept Surg, Bonn, Germany.
   [Theodorou, A.] Ippokrateio Univ Hosp Athens, Dept Surg, Athens, Greece.
   [Stoffels, B.] Cellitinnen Hosp Holy Spirit, Dept Gen & Visceral Surg, Trauma Surg, Cologne, Germany.
   [von Websky, M.] RWTH Aachen Univ Hosp, Dept Gen Visceral & Transplantat Surg, Aachen, Germany.
C3 University of Bonn; RWTH Aachen University; RWTH Aachen University
   Hospital
RP Dohmen, J (通讯作者)，Univ Bonn, Dept Surg, Bonn, Germany.
EM jonas.dohmen@ukbonn.de
RI Dohmen, Jonas/LSL-3019-2024; Kalff, Joerg/U-8580-2017
OI Dohmen, Jonas/0000-0002-6907-3844; 
FX The author(s) declare that no financial support was received for the
   research, authorship, and/or publication of this article.
CR Badia M, 2020, CRIT CARE RES PRACT, V2020, DOI 10.1155/2020/9729814
   Becker HP, 2007, SCAND J SURG, V96, P263, DOI 10.1177/145749690709600402
   Betancourt AS, 2020, ANN MED SURG, V56, P11, DOI 10.1016/j.amsu.2020.06.007
   Bruhin A, 2014, INT J SURG, V12, P1105, DOI 10.1016/j.ijsu.2014.08.396
   Carr JA, 2013, J AM COLL SURGEONS, V216, P135, DOI 10.1016/j.jamcollsurg.2012.09.004
   Coccolini F, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0167-4
   Coccolini F, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0123-8
   Coccolini F, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0026-5
   DuBose JJ, 2013, J TRAUMA ACUTE CARE, V74, P113, DOI 10.1097/TA.0b013e31827891ce
   Eickhoff R, 2019, BMC SURG, V19, DOI 10.1186/s12893-019-0543-3
   Fung S, 2022, LANGENBECK ARCH SURG, V407, P2075, DOI 10.1007/s00423-021-02424-1
   Glowka TR, 2018, J CRIT CARE, V47, P274, DOI 10.1016/j.jcrc.2018.07.024
   Goussous N, 2012, SURGERY, V152, P777, DOI 10.1016/j.surg.2012.07.015
   Hecker A, 2016, LANGENBECK ARCH SURG, V401, P15, DOI 10.1007/s00423-015-1353-4
   Hees A, 2020, CASE REP SURG, V2020, DOI 10.1155/2020/8254804
   Hofmann AT, 2017, SURG ENDOSC, V31, P4717, DOI 10.1007/s00464-017-5547-4
   Knuf KM, 2018, PERIOPER MED-LONDON, V7, DOI 10.1186/s13741-018-0094-7
   Kyoung KH, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0016-7
   Leppäniemi AK, 2010, CRIT CARE, V14, DOI 10.1186/cc8857
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   Mones T, 2024, SURG TECHNOL INT, V44, DOI 10.52198/24.STI.44.HR1781
   Morais Marina, 2018, Porto Biomed J, V3, pe14, DOI [10.1016/j.pbj.0000000000000014, 10.1016/j.pbj.0000000000000014]
   Petersson P, 2019, SCAND J SURG, V108, P216, DOI 10.1177/1457496918818979
   Petersson P, 2020, FRONT SURG, V7, DOI 10.3389/fsurg.2020.577104
   Quyn AJ, 2012, COLORECTAL DIS, V14, pE429, DOI 10.1111/j.1463-1318.2012.03045.x
   Shapiro MB, 2000, J TRAUMA, V49, P969, DOI 10.1097/00005373-200011000-00033
   Smit M, 2020, ANN INTENSIVE CARE, V10, DOI 10.1186/s13613-020-00746-9
   Smith BP, 2010, J GASTROINTEST LIVER, V19, P425
   Teixeira PGR, 2008, AM SURGEON, V74, P891
   Van Damme L, 2018, CRIT CARE, V22, DOI 10.1186/s13054-018-2103-0
   Verdam FJ, 2011, WORLD J SURG, V35, P2348, DOI 10.1007/s00268-011-1210-8
   Wang YF, 2019, WORLD J SURG, V43, P3044, DOI 10.1007/s00268-019-05166-w
   Websky MW., 2017, Zentralblatt F R Chir, V142, P259, DOI DOI 10.1055/S-0042-119303
   Willms A, 2015, LANGENBECK ARCH SURG, V400, P91, DOI 10.1007/s00423-014-1240-4
   Willms AG, 2022, HERNIA, V26, P61, DOI 10.1007/s10029-020-02336-x
   Willms AG, 2021, ANN SURG, V273, P1182, DOI 10.1097/SLA.0000000000003440
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
NR 37
TC 6
Z9 9
U1 0
U2 1
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-875X
J9 FRONT SURG
JI Front. Surg.
PD AUG 13
PY 2024
VL 11
AR 1449702
DI 10.3389/fsurg.2024.1449702
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA D6W3A
UT WOS:001297562300001
PM 39193403
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Li, P
   Li, JH
AF Li, Ping
   Li, Junhong
TI 被撤回的出版物: Effect of incisional negative pressure therapy and conventional
   treatment on wound complications after orthopaedic trauma surgery: A
   meta-analysis of randomized controlled studies (Retracted article. See
   vol. 22, 2025)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article; Retracted Publication
DE deep infections; negative pressure wound therapy; superficial
   infections; wound dehiscence
ID OPEN FRACTURE; INFECTION; DRESSINGS; NPWT
AB The results of this meta-analysis were applied to analyse the effects of Negative Pressure Wound Therapy (NPWT) and conventional dressings on post-surgical outcomes after trauma in orthopaedics. Through June 2023, a full review of the literature has been carried out with the help of 4 databases, PubMed, Embase, Cochrane Library, and the Web of Science. The quality of the literature was evaluated according to the classification and exclusion criteria established for this trial, which led to an analysis of 9 related trials. The results included the injury was deeply and superficially infected, and the wound was dehiscence. The 95% confidence interval (CI) and odds ratios (OR) were computed by means of a fixed-effect and a random-effect model. Meta-analyses were conducted with RevMan 5.3. There is no statistical significance between NPWT and routine therapy for deep wound infection (OR, 1.37; 95% CI, 0.82-2.27, p = 0.23); There was no difference in the incidence of inflammation in the wound than with conventional dressings (OR, 1.10; 95% CI, 0.84-1.45, p = 0.49); But NPWT was obviously superior to that of routine therapy in superficial wound infection (OR, 2.07; 95% CI, 1.32-3.25, p = 0.002) and wound dehiscence (OR, 2.44; 95% CI, 1.31-4.57, p = 0.005); But not with respect to wound exudate. therapy group, but no statistically significant difference was found with respect to wound exudation. (OR, 1.16; 95% CI, 0.86-1.57, p = 0.34). Given that some of the chosen trials are too small for this meta-analysis, caution should be exercised when treating their values. More high-quality research with a large sample is required in order to confirm the findings.
C1 [Li, Ping] Shandong First Med Univ, Dept Orthoped, Peoples Hosp, West Changyou Rd & North Winmu West St, Jinan 271100, Peoples R China.
   [Li, Junhong] Shandong First Med Univ, Dept Cardiac Care Unit, Peoples Hosp, Jinan, Peoples R China.
C3 Shandong First Medical University & Shandong Academy of Medical
   Sciences; Shandong First Medical University & Shandong Academy of
   Medical Sciences
RP Li, P (通讯作者)，Shandong First Med Univ, Dept Orthoped, Peoples Hosp, West Changyou Rd & North Winmu West St, Jinan 271100, Peoples R China.
EM 15563415008@163.com
CR Alverdy JC, 2020, LANCET INFECT DIS, V20, pE38, DOI 10.1016/S1473-3099(19)30756-X
   Arti H, 2016, PAK J MED SCI, V32, P65, DOI 10.12669/pjms.321.8568
   Canton Gianluca, 2020, Acta Biomed, V91, pe2020006, DOI 10.23750/abm.v91i14-S.10784
   Colli A, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-160
   Cooper HJ, 2016, J ARTHROPLASTY, V31, P1047, DOI 10.1016/j.arth.2015.11.010
   Costa ML, 2020, HEALTH TECHNOL ASSES, V24, pI, DOI 10.3310/hta24380
   Costa ML, 2018, HEALTH TECHNOL ASSES, V22, P1, DOI 10.3310/hta22730
   Costa ML, 2018, JAMA-J AM MED ASSOC, V319, P2280, DOI 10.1001/jama.2018.6452
   Crist BD, 2017, INJURY, V48, P1518, DOI 10.1016/j.injury.2017.04.055
   Gao JR, 2021, J ADV NURS, V77, P3980, DOI 10.1111/jan.14876
   Grant-Freemantle MC, 2020, J ORTHOP TRAUMA, V34, P223, DOI 10.1097/BOT.0000000000001750
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Hudson DA, 2015, INT WOUND J, V12, P195, DOI 10.1111/iwj.12080
   Iheozor-Ejiofor Zipporah, 2018, Cochrane Database Syst Rev, V7, pCD012522, DOI 10.1002/14651858.CD012522.pub2
   Kumaar A, 2022, CUREUS J MED SCIENCE, V14, DOI 10.7759/cureus.23727
   Kuo FC, 2021, J ARTHROPLASTY, V36, P2612, DOI 10.1016/j.arth.2021.02.047
   Liu X, 2018, INT J SURG, V53, P72, DOI 10.1016/j.ijsu.2018.02.064
   Namgoong S, 2018, WOUND REPAIR REGEN, V26, pS3, DOI 10.1111/wrr.12576
   Nolff MC, 2016, TIERAERZTL PRAX K H, V44, P26, DOI 10.15654/TPK-150957
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Shao JS, 2018, INT J SURG, V56, P124, DOI 10.1016/j.ijsu.2018.06.018
   Stannard JP, 2012, INT WOUND J, V9, P32, DOI 10.1111/j.1742-481X.2012.01017.x
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Stannard JP, 2010, INJURY, V41, P780, DOI 10.1016/j.injury.2009.08.011
   Suzuki T, 2014, J ORTHOP SURG-HONG K, V22, P30, DOI 10.1177/230949901402200109
   Wang C, 2019, J ORTHOP SURG RES, V14, DOI 10.1186/s13018-019-1488-z
   Wang Z, 2019, INT J CLIN EXP MED, V12, P13839
   Whitehouse JD, 2002, INFECT CONT HOSP EP, V23, P183, DOI 10.1086/502033
   Yang Charlie C, 2006, J Surg Orthop Adv, V15, P19
   Zhou JM, 2020, SPINE, V45, P208, DOI 10.1097/BRS.0000000000003218
NR 31
TC 3
Z9 3
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2023
VL 20
IS 10
BP 4291
EP 4299
DI 10.1111/iwj.14331
EA AUG 2023
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CH3W9
UT WOS:001041841300001
PM 37534409
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Tulimieri, MT
   Callas, PW
   Bertges, DJ
AF Tulimieri, Maxwell T.
   Callas, Peter W.
   Bertges, Daniel J.
TI Effectiveness of Closed Incision Negative Pressure Wound Therapy for
   Suprainguinal Bypass in the Vascular Quality Initiative
SO ANNALS OF VASCULAR SURGERY
LA English
DT Article
ID OUTCOMES
AB Background: We sought to explore the utility of closed incision negative pressure wound therapy (ciNPWT) in prevention of groin wound complications after suprainguinal bypass using a national quality improvement database reflective of real-world practice. Methods: The Vascular Quality Initiative was queried for suprainguinal bypass procedures from December 2019 to August 2023. Propensity matching was performed comparing ciNPWT versus standard dressings at (1) the index hospitalization (full cohort) and (2) 30 days (subgroup). The primary outcome was surgical site infection (SSI) at 30 days. Secondary outcomes included in-hospital SSI, return to operating room for infection, discharge disposition, length of stay and 30-day readmission rate, noninfectious wound complications, and mortality. Results: The propensity-matched cohort consisted of 3,467 of a total of 5,082 patients undergoing suprainguinal bypass. Within the propensity-matched full cohort, 2,680 (77%) received standard dressing and 787 (23%) ciNPWT. Of those, 337 (61%) in the standard group and 150 (31%) in the ciNPWT group had 30-day follow-up data. There was a significant decrease in the rates of in-hospital SSI for those with ciNPWT at 2% compared to those with standard dressing at 4% (P - 0.02). There was no difference in 30-day SSI between groups with 3% in the ciNPWT group and 4% in the standard group (P - 0.40). After adjusting, there was no differences in 30-day readmission rates (P - 0.37), 30-day noninfectious wound complications (P - 0.28), 30-day mortality (P - 0.24), discharge disposition (P - 0.82), or length of stay (P Conclusions: In this Vascular Quality Initiative analysis of suprainguinal bypass, we observed a decrease in the in-hospital SSI rate but no difference in the SSI or noninfectious wound complications at 30 days for patients treated with ciNPWT versus standard dressings. Given these findings, consideration should be given to conducting an adequately powered randomized control trial of ciNPWT targeted for suprainguinal bypass.
C1 [Tulimieri, Maxwell T.] Michigan State Univ, Spectrum Hlth Meijer Heart Ctr, Dept Vasc Surg, Grand Rapids, MI USA.
   [Callas, Peter W.] Univ Vermont, Med BioStat, Burlington, VT 05401 USA.
   [Bertges, Daniel J.] Univ Vermont, Med Ctr, Div Vasc Surg & Endovasc Therapy, Burlington, VT 05401 USA.
C3 Michigan State University; University of Vermont; University of Vermont
   Medical Center; University of Vermont
RP Bertges, DJ (通讯作者)，Univ Vermont, Med Ctr, Div Vasc Surg, Surg & Med, 111 Colchester Ave,Smith 338, Burlington, VT 05401 USA.
EM daniel.bertges@uvmhealth.org
CR Austin PC, 2011, MULTIVAR BEHAV RES, V46, P399, DOI 10.1080/00273171.2011.568786
   Bertges DJ, 2016, J VASC SURG, V64, P1411, DOI 10.1016/j.jvs.2016.04.045
   Diamond KR, 2019, J VASC SURG, V69, P1831, DOI 10.1016/j.jvs.2018.08.195
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Gwilym BL, 2021, EUR J VASC ENDOVASC, V61, P636, DOI 10.1016/j.ejvs.2020.11.053
   Hardouin S, 2020, J VASC SURG, V71, P862, DOI 10.1016/j.jvs.2019.05.038
   Hasselmann J, 2020, ANN SURG, V271, P48, DOI 10.1097/SLA.0000000000003364
   Heinze G, 2011, EUR HEART J, V32, P1704, DOI 10.1093/eurheartj/ehr031
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Madigan Michael C, 2021, J Vasc Surg, V73, P1715, DOI [10.1016/j.jvs.2020.08.139, 10.1016/j.jvs.2020.08.139]
   McGillicuddy EA, 2016, J VASC SURG, V64, P1780, DOI 10.1016/j.jvs.2016.05.068
   Robbins JM, 2023, J VASC SURG, V77, P1836, DOI 10.1016/j.jvs.2023.01.209
   Saadeddin ZM, 2019, EUR J VASC ENDOVASC, V58, P529, DOI 10.1016/j.ejvs.2019.02.010
   Scali ST, 2021, J VASC SURG, V73, P1031, DOI 10.1016/j.jvs.2020.06.119
   Stewart LM, 2021, J VASC SURG, V73, P1991, DOI 10.1016/j.jvs.2020.11.039
   Strobel RM, 2022, LANGENBECK ARCH SURG, V407, P819, DOI 10.1007/s00423-021-02346-y
   Tulimieri MT, 2024, ANN VASC SURG, V102, P47, DOI 10.1016/j.avsg.2023.11.050
   vqi, 2024, About us
   Wee IJY, 2019, EUR J VASC ENDOVASC, V58, P446, DOI 10.1016/j.ejvs.2018.12.021
NR 19
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD FEB
PY 2025
VL 111
BP 241
EP 249
DI 10.1016/j.avsg.2024.11.008
EA DEC 2024
PG 9
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA R1U5T
UT WOS:001389388700001
PM 39581317
DA 2026-07-24
ER

PT J
AU Balan, N
   Qi, X
   Keeley, J
   Neville, A
AF Balan, Naveen
   Qi, Xin
   Keeley, Jessica
   Neville, Angela
TI A Novel Strategy to Manage Below-Knee-Amputation (BKA) Stump
   Complications for Early Wound Healing and BKA Salvage
SO AMERICAN SURGEON
LA English
DT Article
DE acute care surgery; ambulatory status; negative pressure wound therapy;
   severe diabetic foot infection; time to prosthesis
ID LOWER-EXTREMITY AMPUTATION; RISK-FACTORS; READMISSION; SERIES
AB Introduction The optimal management of major stump complications (operative infection or dehiscence) following below-knee-amputation (BKA) is unknown. We evaluated a novel operative strategy to aggressively treat major stump complications hypothesizing it would improve our rate of BKA salvage. Methods Retrospective review of patients requiring operative intervention for BKA stump complications between 2015 and 2021. A novel strategy employing staged operative debridement for source control, negative pressure wound therapy, and reformalization was compared to standard care (less structured operative source control or above knee amputation). Results 32 patients were studied, 29 of which were male (90.6%) with an average age of 56.1 +/- 9.6 y. 30 (93.8%) had diabetes and 11 (34.4%) peripheral arterial disease (PAD). The novel strategy was used in 13 patients and 19 had standard care. Novel strategy patients had higher BKA salvage rates, 100% vs 73.7% (P = .064), and postoperative ambulatory status, 84.6% vs 57.9% (P = .141). Importantly, none of the patients undergoing the novel therapy had PAD, while all progressing to above-knee amputation (AKA) did. To better assess the efficacy of the novel technique, patients progressing to AKA were excluded. Patients undergoing novel therapy who had their BKA level salvaged (n = 13) were compared to usual care (n = 14). The novel therapy's time to prosthetic referral was 72.8 +/- 53.7 days vs 247 +/- 121.6 days (P < .001), but they did undergo more operations (4.3 +/- 2.0 vs 1.9 +/- 1.1, P < .001). Conclusion Utilization of a novel operative strategy for BKA stump complications is effective in salvaging BKAs, particularly for patients without PAD.
C1 [Balan, Naveen; Qi, Xin; Keeley, Jessica; Neville, Angela] Harbor UCLA Med Ctr, Harbor, OR USA.
   [Neville, Angela] Harbor UCLA Med Ctr, 1000 W Carson St, Torrance, CA 90502 USA.
C3 University of California System; University of California Los Angeles;
   University of California Los Angeles Medical Center
RP Neville, A (通讯作者)，Harbor UCLA Med Ctr, 1000 W Carson St, Torrance, CA 90502 USA.
EM aneville@dhs.lacounty.gov
RI Qi, Xin/JCE-7825-2023
OI Qi, Xin/0000-0003-4066-8710; Balan, Naveen/0000-0002-7233-1306; Neville,
   Angela/0000-0002-7660-4711; Keeley, Jessica/0000-0001-6196-5330
CR Aulivola B, 2004, ARCH SURG-CHICAGO, V139, P395, DOI 10.1001/archsurg.139.4.395
   Capobianco Claire M, 2009, Clin Podiatr Med Surg, V26, P619, DOI 10.1016/j.cpm.2009.08.002
   Carvalho JA, 2012, PROSTHET ORTHOT INT, V36, P236, DOI 10.1177/0309364611430535
   Chopra A, 2018, J VASC SURG, V67, P1521, DOI 10.1016/j.jvs.2017.10.051
   Creager MA, 2021, CIRCULATION, V143, pE875, DOI 10.1161/CIR.0000000000000967
   Cruz CP, 2003, AM J SURG, V186, P449, DOI 10.1016/j.amjsurg.2003.07.027
   Curran T, 2014, J VASC SURG, V60, P1315, DOI 10.1016/j.jvs.2014.05.050
   Jeffery K., 2018, ORTHOPEDIC P, V92, P227
   MacCallum KP, 2021, ANN VASC SURG, V71, P331, DOI 10.1016/j.avsg.2020.07.038
   Phair J, 2018, J VASC SURG, V67, P848, DOI 10.1016/j.jvs.2017.08.061
   Ploeg AJ, 2005, EUR J VASC ENDOVASC, V29, P633, DOI 10.1016/j.ejvs.2005.02.014
   Stasik CN, 2008, WORLD J SURG, V32, P1823, DOI 10.1007/s00268-008-9500-5
   Wong LH, 2021, CLIN ORTHOP RELAT R, V479, P324, DOI 10.1097/CORR.0000000000001455
NR 13
TC 4
Z9 4
U1 0
U2 1
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0003-1348
EI 1555-9823
J9 AM SURGEON
JI Am. Surg.
PD OCT
PY 2023
VL 89
IS 10
BP 4055
EP 4060
DI 10.1177/00031348231175504
EA MAY 2023
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA Y7BE9
UT WOS:001001013900001
PM 37195758
OA hybrid
DA 2026-07-24
ER

PT J
AU Cong, B
   Chen, MQ
AF Cong, Bo
   Chen, Mingqi
TI 被撤回的出版物: Evaluating the efficacy of combined flap coverage,
   antibiotic-loaded bone cement and negative pressure irrigation in
   traumatic osteomyelitis management (Retracted article. See vol. 22,
   2025)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article; Retracted Publication
DE antibiotic bone cement; negative pressure wound therapy; skin flap
   coverage; soft tissue defects; traumatic osteomyelitis
ID POSTTRAUMATIC OSTEOMYELITIS; EXTERNAL FIXATOR; WOUND THERAPY;
   PATHOPHYSIOLOGY; DEFECTS
AB Traumatic osteomyelitis with accompanying soft tissue defects presents a significant therapeutic challenge. This prospective, randomised controlled trial aims to evaluate the efficacy of antibiotic-impregnated bone cement, flap coverage and negative pressure sealed irrigation in the management of traumatic osteomyelitis complicated by soft tissue defects. A total of 46 patients with clinically diagnosed traumatic osteomyelitis and soft tissue defects were randomised into a control group (n = 23) and an observation group (n = 23). The control group underwent standard flap coverage and negative-pressure lavage, while the observation group received an additional treatment with antibiotic-loaded bone cement. Efficacy was measured based on clinical criteria, surgical metrics and morphometric assessment of bone and soft tissue defects. Statistical analyses were performed using SPSS version 27.0. The observation group, treated with an integrated approach of flap coverage, negative pressure wound therapy (NPWT) and antibiotic-impregnated bone cement, demonstrated significantly higher overall treatment efficacy (91.3%) compared to the control group, which received only flap coverage and NPWT (65.2%) (p < 0.01). This enhanced efficacy was evidenced through various outcomes: the observation group experienced reduced surgical times, shorter hospital stays, fewer dressing changes and accelerated wound healing, all statistically significant (p < 0.001). Additionally, a quantitative analysis at 6-month post-treatment revealed that the observation group showed more substantial reductions in both bone and soft tissue defect sizes compared to the control group (p < 0.001). The multi-modal treatment strategy, combining skin flap coverage, antibiotic bone cement and negative-pressure irrigation, showed marked efficacy in treating traumatic osteomyelitis and associated soft tissue defects. This approach accelerated postoperative recovery and lowered costs.
C1 [Cong, Bo; Chen, Mingqi] Binzhou Med Univ, Dept Orthoped, Dept Pediat, Yantaishan Hosp, Yantai, Peoples R China.
   [Cong, Bo; Chen, Mingqi] Binzhou Med Univ, Yantaishan Hosp, Yantai Key Lab Repair & Reconstruct Bone & Joint, Yantai, Peoples R China.
C3 Shandong Medical & Pharmaceutical University; Shandong Medical &
   Pharmaceutical University
RP Chen, MQ (通讯作者)，Binzhou Med Univ, Yantaishan Hosp, Yantai Key Lab Repair & Reconstruct Bone & Joint, 10087 Keji Ave, Yantai 264003, Peoples R China.
EM chenmingqi185@163.com
FU Yantai Science and Technology Innovation Development Plan Project
FX We express our heartfelt gratitude to all the patients who participated
   in this study. Their willingness to contribute and their informed
   consent have been instrumental in advancing our research. We also thank
   our colleagues and team members for their relentless support and
   assistance throughout the course of this study.
CR Antonini A, 2017, INJURY, V48, pS76, DOI 10.1016/S0020-1383(17)30663-0
   Arowojolu OA, 2021, PLAST RECONSTR SURG, V147, p61S, DOI 10.1097/PRS.0000000000007613
   Birt MC, 2017, J ORTHOP, V14, P45, DOI 10.1016/j.jor.2016.10.004
   George Prakash K, 2021, J Orthop Case Rep, V11, P52, DOI [10.13107/jocr.2021.v11.i03.2084, 10.13107/jocr.2021.v11.i03.2084]
   Haidari S, 2021, BIOMED RES INT, V2021, DOI 10.1155/2021/7742227
   Kang YQ, 2023, SCI REP-UK, V13, DOI 10.1038/s41598-023-49460-z
   Lew DP, 2004, LANCET, V364, P369, DOI 10.1016/S0140-6736(04)16727-5
   Madrigal P, 2022, J TISSUE VIABILITY, V31, P630, DOI 10.1016/j.jtv.2022.10.002
   Maruccia M, 2018, INJURY, V49, pS105, DOI 10.1016/j.injury.2018.09.048
   Mckee MD, 2010, J ORTHOP TRAUMA, V24, P483, DOI 10.1097/BOT.0b013e3181df91d9
   Momodu I.I., 2023, Osteomyelitis
   Morisaki A, 2022, J CARDIAC SURG, V37, P2745, DOI 10.1111/jocs.16700
   Mundra LS, 2022, J ORTHOP TRAUMA, V36, pE374, DOI 10.1097/BOT.0000000000002406
   Ng PH, 2022, SINGAP MED J, V63, P486, DOI 10.11622/smedj.2021040
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   Oliver TI., 2023, StatPearls
   PARKER RB, 1987, VET CLIN N AM-SMALL, V17, P841, DOI 10.1016/S0195-5616(87)50080-8
   Qiu XS, 2017, BMC MUSCULOSKEL DIS, V18, DOI 10.1186/s12891-017-1614-1
   Qiu XS, 2015, BMC MUSCULOSKEL DIS, V16, DOI 10.1186/s12891-015-0704-1
   Rajendran M, 2021, RECENT PAT NANOTECH, V15, P70, DOI 10.2174/1872210514666200811103724
   Ren YL, 2023, INT J SURG, V109, P2721, DOI 10.1097/JS9.0000000000000502
   Ribeiro Marta, 2012, Biomatter, V2, P176, DOI 10.4161/biom.22905
   Rodham P, 2023, EUR J TRAUMA EMERG S, V49, P539, DOI 10.1007/s00068-022-02104-9
   ROESGEN M, 1989, ARCH ORTHOP TRAUM SU, V108, P1, DOI 10.1007/BF00934149
   Rupp M, 2023, J BONE JOINT INFECT, V8, P165, DOI 10.5194/jbji-8-165-2023
   Schmitt SK, 2017, INFECT DIS CLIN N AM, V31, P325, DOI 10.1016/j.idc.2017.01.010
   Shen Yuming, 2013, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V27, P1061
   Stahel PF, 2016, EUR J TRAUMA EMERG S, V42, P395, DOI 10.1007/s00068-016-0707-0
   Tang Buqi, 2021, Zhong Nan Da Xue Xue Bao Yi Xue Ban, V46, P1290, DOI 10.11817/j.issn.1672-7347.2021.200621
   Teot L, 2021, PLAST RECONSTR SURG, V147, p9S, DOI 10.1097/PRS.0000000000007628
   Tsukayama DT, 1999, CLIN ORTHOP RELAT R, P22
   Wagner RK, 2023, STRATEG TRAUMA LIMB, V18, P73, DOI [10.5005/jp-journals-10080-1586, 10.5005/jp-journals-10080-1586]
   Wang X, 2016, BONE JOINT RES, V5, P101, DOI 10.1302/2046-3758.53.2000487
   Xu T, 2022, CHIN J TRAUMATOL, V25, P325, DOI 10.1016/j.cjtee.2022.06.001
   Yang J, 2021, CHIN J TRAUMATOL, V24, P320, DOI 10.1016/j.cjtee.2021.07.006
   Zhang ST, 2016, J ORTHOP SCI, V21, P493, DOI 10.1016/j.jos.2016.04.010
   Zhang Z, 2022, INJURY, V53, P3486, DOI 10.1016/j.injury.2022.07.029
   Zhou RC, 2023, POL J MICROBIOL, V72, P239, DOI 10.33073/pjm-2023-024
NR 38
TC 2
Z9 2
U1 0
U2 10
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD JAN
PY 2024
VL 21
IS 1
AR e14650
DI 10.1111/iwj.14650
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA FE7G0
UT WOS:001144145500001
PM 38272791
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Izawa, Y
   Nishida, M
   Futamura, K
   Murakami, H
   Sato, K
   Tsuchida, Y
AF Izawa, Yuta
   Nishida, Masahiro
   Futamura, Kentaro
   Murakami, Hiroko
   Sato, Kazuo
   Tsuchida, Yoshihiko
TI Staged wound closure using tension-reducing taping technique with
   negative pressure wound therapy in lower extremity open fractures: A
   retrospective review
SO JOURNAL OF ORTHOPAEDIC SCIENCE
LA English
DT Review
DE Open fracture; Primary wound closure; Staged wound closure; Wound edge
   necrosis
ID SHOELACE TECHNIQUE; FASCIOTOMY; RECONSTRUCTION; MANAGEMENT; INFECTION;
   TRAUMA; FLAP
AB Background: In the treatment of lower extremity open fractures Gustilo-Anderson classification types IIIA/IIIB borderline cases, closing open wound under strong tension may lead to wound edge necrosis and the need for soft tissue reconstruction. The purpose of this study is to examine whether staged wound closure using tension-reducing taping with negative pressure wound therapy (NPWT) could prevent wound edge necrosis in borderline type lower extremity open fractures. Materials and methods: Patients with IIIA/IIIB borderline type lower extremity open fractures who were treated at our institution were included. The patients were divided into two groups: those who underwent conventional wound closure (Group 1) and those who underwent staged closure using tensionreducing taping (Group 2). Characteristics of patients and their injuries were compared between the two groups. In addition, the presence or absence of wound edge necrosis after wound closure, soft tissue reconstruction, and wound infection were compared between the two groups. Results: Twenty-six patients were included in Group 1 and 21 patients were included in Group 2. There were no significant differences in characteristics of patients and their injuries between the two groups. The rate of wound edge necrosis and the need for local flaps were significantly higher in Group 1 (p = 0.002, 0.027). There was no significant difference in infection rates between the two groups (p = 0.495). Conclusion: For IIIA/IIIB borderline type lower extremity open fractures, staged wound closure using tension-reducing taping technique with NPWT can reduce wound edge necrosis and prevent the transition to iatrogenic type IIIB. (c) 2025 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
C1 [Izawa, Yuta; Nishida, Masahiro; Futamura, Kentaro; Tsuchida, Yoshihiko] Shonan Kamakura Gen Hosp, Dept Trauma Ctr, 1370-1 Okamoto, Kamakura, Kanagawa, Japan.
   [Izawa, Yuta; Murakami, Hiroko; Sato, Kazuo; Tsuchida, Yoshihiko] Sapporo Higashi Tokushukai Hosp, Dept Orthoped, Trauma Ctr, Kita 33 Jou Higashi 14 Chome 3-1, Sapporo, Hokkaido, Japan.
RP Izawa, Y (通讯作者)，Shonan Kamakura Gen Hosp, Dept Trauma Ctr, 1370-1 Okamoto, Kamakura, Kanagawa, Japan.
EM yutaizawa18@gmail.com; drmint2001@yahoo.co.jp; kenshin@friend.ocn.ne.jp;
   hmura@pb3.so-net.ne.jp; tetukazu812@gmail.com; ytutida@world.ocn.ne.jp
CR Asgari MM, 2000, ANN PLAS SURG, V44, P225, DOI 10.1097/00000637-200044020-00017
   Blum ML, 2012, J ORTHOP TRAUMA, V26, P499, DOI 10.1097/BOT.0b013e31824133e3
   Giannoudis PV, 2009, INJURY, V40, P213, DOI 10.1016/j.injury.2008.05.024
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Gopal S, 2000, J BONE JOINT SURG BR, V82B, P959, DOI 10.1302/0301-620X.82B7.10482
   Gopal S, 2004, J BONE JOINT SURG BR, V86B, P861, DOI 10.1302/0301-620X.86B6.13400
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Jauregui Julio J, 2017, J Orthop Surg (Hong Kong), V25, p2309499016684724, DOI [10.1177/2309499016684724, 10.1177/2309499016684724]
   Kanda Y, 2013, BONE MARROW TRANSPL, V48, P452, DOI 10.1038/bmt.2012.244
   Lee JY, 2014, WORLD J EMERG SURG, V9, DOI 10.1186/1749-7922-9-29
   Parrett BM, 2006, PLAST RECONSTR SURG, V117, P1315, DOI 10.1097/01.prs.0000204959.18136.36
   Putnis Sven, 2014, Open Orthop J, V8, P142, DOI 10.2174/1874325001408010142
   Rajasekaran S, 2007, INJURY, V38, P890, DOI 10.1016/j.injury.2007.01.013
   Rajasekaran S, 2009, J BONE JOINT SURG BR, V91B, P217, DOI 10.1302/0301-620X.91B2.21228
   Scharfenberger AV, 2017, J ORTHOP TRAUMA, V31, P121, DOI 10.1097/BOT.0000000000000751
   Sinha K, 2013, ADV ORTHOP, V2013, DOI 10.1155/2013/245940
   Taylor RC, 2003, J AM COLL SURGEONS, V197, P872, DOI 10.1016/S1072-7515(03)00646-X
   Wiger P, 2000, SCAND J PLAST RECONS, V34, P315
   Zorrilla P, 2005, J TRAUMA, V59, P1515, DOI 10.1097/01.ta.0000199242.24511.30
NR 20
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 0949-2658
EI 1436-2023
J9 J ORTHOP SCI
JI J. Orthop. Sci.
PD NOV
PY 2025
VL 30
IS 6
BP 1121
EP 1125
DI 10.1016/j.jos.2025.03.002
EA NOV 2025
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA J0970
UT WOS:001627207100015
PM 40122733
DA 2026-07-24
ER

PT J
AU Vinnicombe, Z
   Singh, G
   Spiers, J
   Pouncey, AL
   McEvoy, H
   Lancaster, K
AF Vinnicombe, Z.
   Singh, G., V
   Spiers, J.
   Pouncey, A. L.
   McEvoy, H.
   Lancaster, K.
TI Comparison of Negative Pressure Wound Therapy with or without a
   Split-Thickness Skin Graft in the Surgical Management of Axillary
   Hidradenitis Suppurativa: A Retrospective Cohort Study
SO PLASTIC SURGERY
LA English
DT Article
DE dermatology; hidradenitis suppurativa; patient-reported outcome
   measures; plastic surgery; reconstruction; skin
ID EXCISION; SURGERY; RECURRENCE; GUIDELINES; EXPERIENCE; CLOSURE; FLAP
AB Introduction: Negative pressure wound therapy (NPWT) alone or with the addition of a split-thickness skin graft (STSG) are 2 reconstructive options available after surgical excision of axillary hidradenitis suppurativa (HS). The aim of this study was to retrospectively examine patients undergoing these treatments and to assess clinical and patient-related outcome measures. Methods: A single-centre, retrospective analysis was conducted, evaluating surgical excision of axillary HS, with STSG and NPWT, or NPWT alone. Data collected included No. of post-operative clinic visits, time to heal, size of wound, disease recurrence, follow-up time, Dermatology Life Quality Index (DLQI), the Generalised Anxiety Disorder Assessment (GAD-7), the Patient Health Questionnaire Depression Scale (PHQ-9), Pain Visual Analogue Scale (PAINVAS2), the Brief Illness Perception Questionnaire (BIPQ), and Dermatology Visual Analogue Scale (DERMVAS). Two-tailed t-test and Mann-Whitney Wilcoxon U-tests were used to assess for significant relationships. Results: One hundred five patients were included in the study, 44 who received NPWT alone, and 61 who received NPWT + STSG. There was no significant difference in follow-up time (P = .934) or No. of follow-up appointments between groups (P = .287). There was a significant difference in time to heal between groups, with STSG + NPWT observing a mean time of 2.77 months and NPWT alone observing a mean time of 4.40 months (P = .0006). There was no difference in patient-reported outcomes between the 2 groups. Conclusion: There is no difference in patient-reported outcomes with the addition of an STSG to NPWT after surgical excision of HS. Wide excision and use of NPWT alone is an effective procedure for the treatment of axillary HS.
C1 [Vinnicombe, Z.; Pouncey, A. L.; McEvoy, H.; Lancaster, K.] St Thomas Hosp, Dept Plast & Reconstruct Surg, London SE1 7EH, England.
   [Singh, G., V; Spiers, J.] Kings Coll London, GKT Sch Med Educ, London, England.
C3 Guy's & St Thomas' NHS Foundation Trust; University of London; King's
   College London
RP Vinnicombe, Z (通讯作者)，St Thomas Hosp, Dept Plast & Reconstruct Surg, London SE1 7EH, England.
EM zvinnicombe@gmail.com
RI ; Pouncey, Anna Louise/HJB-2757-2022
OI Spiers, Jessica/0000-0002-3207-8588; Vinnicombe,
   Zak/0000-0003-0493-5682; Singh, Gurdas/0000-0003-1604-5353; Pouncey,
   Anna Louise/0000-0003-2329-6193
CR Alharbi Z, 2012, BMC DERMATOL, V12, DOI 10.1186/1471-5945-12-9
   Alikhan A, 2009, J AM ACAD DERMATOL, V60, P539, DOI 10.1016/j.jaad.2008.11.911
   [Anonymous], 2020, R: A language and environment for statistical computing
   Ather Shahzad, 2006, Int Wound J, V3, P159, DOI 10.1111/j.1742-481X.2006.00235.x
   Chen E, 2011, ANN PLAS SURG, V67, P397, DOI 10.1097/SAP.0b013e3181f77bd6
   Deckers IE, 2018, J EUR ACAD DERMATOL, V32, P459, DOI 10.1111/jdv.14770
   FINLAY AY, 1994, CLIN EXP DERMATOL, V19, P210, DOI 10.1111/j.1365-2230.1994.tb01167.x
   Grunfeld E, 1999, BRIT J CANCER, V79, P1227, DOI 10.1038/sj.bjc.6690197
   Hynes PJ, 2002, BRIT J PLAST SURG, V55, P507, DOI 10.1054/bjps.2002.3899
   Ingram JR, 2019, BRIT J DERMATOL, V180, P1009, DOI 10.1111/bjd.17537
   Ingram JR, 2018, BRIT J DERMATOL, V178, P917, DOI 10.1111/bjd.16101
   Jemec GBE, 2012, NEW ENGL J MED, V366, P158, DOI 10.1056/NEJMcp1014163
   Johnson BC., 2019, COCHRANE HDB SYSTEMA
   Klassen AF, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001672
   Kroenke K, 2001, J GEN INTERN MED, V16, P606, DOI 10.1046/j.1525-1497.2001.016009606.x
   Kurzen H, 2008, EXP DERMATOL, V17, P455, DOI [10.1111/j.1600-0625.2008.00712_1.x, 10.1111/j.1600-0625.2008.00712.x]
   Mandal A, 2005, SURG-J R COLL SURG E, V3, P23, DOI 10.1016/S1479-666X(05)80006-X
   Margesson LJ, 2014, BEST PRACT RES CL OB, V28, P1013, DOI 10.1016/j.bpobgyn.2014.07.012
   Marvel J, 2019, BMJ OPEN, V9, DOI 10.1136/bmjopen-2019-030579
   Mehdizadeh A, 2015, J AM ACAD DERMATOL, V73, pS70, DOI 10.1016/j.jaad.2015.07.044
   Naldi L., 2006, Hidradenitis suppurativa, P58, DOI [DOI 10.1007/978-3-540-33101-8_8, 10.1007/978-3-540-33101-8_8]
   Pearce FB, 2017, J WOUND CARE, V26, pS36, DOI 10.12968/jowc.2017.26.Sup1.S36
   Quemby DJ, 2014, BJA EDUC, V14, P256, DOI 10.1093/bjaceaccp/mkt066
   Revuz JE, 2008, J AM ACAD DERMATOL, V59, P596, DOI 10.1016/j.jaad.2008.06.020
   Ritz JP, 1998, INT J COLORECTAL DIS, V13, P164, DOI 10.1007/s003840050159
   Rompel R, 2000, DERMATOL SURG, V26, P638, DOI 10.1046/j.1524-4725.2000.00043.x
   Ruan QZ, 2018, J SURG RES, V229, P200, DOI 10.1016/j.jss.2018.04.007
   Slade DEM, 2003, BRIT J PLAST SURG, V56, P451, DOI 10.1016/S0007-1226(03)00177-2
   Soldin MG, 2000, BRIT J PLAST SURG, V53, P434, DOI 10.1054/bjps.1999.3285
   Spitzer RL, 1999, JAMA-J AM MED ASSOC, V282, P1737, DOI 10.1001/jama.282.18.1737
   Spitzer RL, 2006, ARCH INTERN MED, V166, P1092, DOI 10.1001/archinte.166.10.1092
   Sugio Y, 2016, PRS-GLOB OPEN, V4, DOI 10.1097/GOX.0000000000001128
   Tanaka A, 2001, ANN PLAS SURG, V47, P636, DOI 10.1097/00000637-200112000-00010
   Tang JB, 2015, INT WOUND J, V12, P334, DOI 10.1111/iwj.12116
   Theut Riis P, 2016, ACTA DERM-VENEREOL, V96, P222, DOI 10.2340/00015555-2129
   van Rappard DC, 2012, J EUR ACAD DERMATOL, V26, P898, DOI 10.1111/j.1468-3083.2011.04203.x
   von Elm E, 2007, BMJ-BRIT MED J, V335, P806
   Wolkenstein P, 2007, J AM ACAD DERMATOL, V56, P621, DOI 10.1016/j.jaad.2006.08.061
   Wormald JCR, 2014, J PLAST RECONSTR AES, V67, P1118, DOI 10.1016/j.bjps.2014.04.032
   Yamashita Y, 2014, DERMATOL SURG, V40, P110, DOI 10.1111/dsu.12400
NR 40
TC 2
Z9 2
U1 0
U2 3
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 2292-5503
EI 2292-5511
J9 PLAST SURG-CHIR PLAS
JI Plast. Surg.
PD MAY
PY 2024
VL 32
IS 2
BP 314
EP 320
AR 22925503221109006
DI 10.1177/22925503221109006
EA JUN 2022
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA OI0L4
UT WOS:000818556700001
PM 38681254
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Carney, BC
   Moffatt, LT
   Travis, TE
   Nisar, S
   Keyloun, JW
   Prindeze, NJ
   Oliver, MA
   Kirkpatrick, LD
   Shupp, JW
AF Carney, Bonnie C.
   Moffatt, Lauren T.
   Travis, Taryn E.
   Nisar, Saira
   Keyloun, John W.
   Prindeze, Nicholas J.
   Oliver, Mary A.
   Kirkpatrick, Liam D.
   Shupp, Jeffrey W.
TI A Pilot Study of Negative Pressure Therapy with Autologous Skin Cell
   Suspensions in a Porcine Model
SO JOURNAL OF SURGICAL RESEARCH
LA English
DT Article
DE Autologous skin cell suspension (ASCS); RECELL System; Negative pressure
   wound therapy (NPWT); Meshed split thickness skin grafting; Burn wounds,
   Duroc pig
ID BURN DEPTH; WOUND THERAPY; PIG; INJURY; MANAGEMENT; GRAFTS; TRIAL;
   SCARS; TIME
AB Background: Negative pressure wound therapy (NPWT) is an option for securing meshed split thickness skin grafts (mSTSGs) after burn excision to optimize skin graft adherence. Recently, the use of autologous skin cell suspension (ASCS) has been approved for use in the treatment of burn injuries in conjunction with mSTSGs.To date, limited data exists regarding the impact of NPWT on healing outcomes when the cellular suspension is utilized. It was hypothesized that NPWT would not negatively impact wound healing of ASCS+mSTSG.
   Materials and Methods: A burn, excision, mSTSG, ASCS +/- NPWT model was used. Two Duroc pigs were utilized in this experiment, each with 2 sets of paired burns. Four wounds received mSTSG+ASCS+NPWT through post-operative day 3, and 4 wounds received mSTSG +ACSC+ traditional ASCS dressings. Cellular viability was characterized prior to spraying. Percent re-epithelialization, graft-adherence, pigmentation, elasticity, and blood perfusion and blood vessel density were assessed at multiple time points through 2 weeks.
   Results: All wounds healed within 14 days with minimal scar pathology and no significant differences in percent re-epithelialization between NPWT, and non-NPWT wounds were ob-served. Additionally, no differences were detected for pigmentation, perfusion, or blood vessel density. NPWT treated wounds had less graft loss and improved elasticity, with elasticity being statistically different.
   Conclusions: These data suggest the positive attributes of the cellular suspension delivered are retained following the application of negative pressure. Re-epithelialization, revascularization, and repigmentation are not adversely impacted. The use of NPWT may be considered as an option when using ASCS with mSTSGs for the treatment of full-thickness burns. (C) 2021 The Authors. Published by Elsevier Inc.
C1 [Carney, Bonnie C.; Moffatt, Lauren T.; Shupp, Jeffrey W.] Georgetown Univ, Med Ctr, Dept Biochem & Mol & Cellular Biol, Washington, DC 20007 USA.
   [Carney, Bonnie C.; Moffatt, Lauren T.; Travis, Taryn E.; Nisar, Saira; Keyloun, John W.; Prindeze, Nicholas J.; Oliver, Mary A.; Kirkpatrick, Liam D.; Shupp, Jeffrey W.] MedStar Hlth Res Inst, FirefightersBurn & Surg Res Lab, Washington, DC USA.
   [Travis, Taryn E.; Shupp, Jeffrey W.] MedStar Washington Hosp Ctr, Burn Ctr, Dept Surg, Washington, DC USA.
   [Keyloun, John W.; Prindeze, Nicholas J.] MedStar Washington Hosp Ctr, Dept Surg, Washington, DC USA.
   [Keyloun, John W.; Prindeze, Nicholas J.] MedStar Georgetown Univ Hosp, Washington, DC USA.
   [Carney, Bonnie C.; Moffatt, Lauren T.; Travis, Taryn E.; Shupp, Jeffrey W.] Georgetown Univ, Dept Surg, Sch Med, Washington, DC USA.
C3 Georgetown University; MedStar Health Research Institute; MedStar
   Washington Hospital Center; MedStar Washington Hospital Center;
   Georgetown University; Georgetown University
RP Shupp, JW (通讯作者)，Bum Ctr, 110 Irving St NW,Suite 3B-55, Washington, DC 20010 USA.
EM jeffrey.w.shupp@medstar.net
RI Travis, Taryn/AAK-8527-2021; Shupp, Jeffrey/AAW-3481-2021
OI Kirkpatrick, Liam/0000-0002-2744-9102
FU AVITA Medical
FX This work was funded by AVITA Medical. The NWPT devices were obtained as
   a donation from KCI. Dr. Shupp is a consultant for AVITA Medical.
CR [Anonymous], 1965, BMJ-BRIT MED J, V1, P1622
   Bailey JK, 2018, LASER SURG MED, V50, P78, DOI 10.1002/lsm.22702
   Brenner Michaela, 2008, Drug Discov Today Dis Mech, V5, pe189, DOI 10.1016/j.ddmec.2008.02.001
   Caldwell F. T. Jr., 1996, Journal of Burn Care and Rehabilitation, V17, P137, DOI 10.1097/00004630-199603000-00007
   Carney BC, 2019, J BURN CARE RES, V40, P58, DOI 10.1093/jbcr/iry045
   Carney BC, 2017, J BURN CARE RES, V38, P28, DOI 10.1097/BCR.0000000000000413
   Chan QE, 2012, J BURN CARE RES, V33, pE43, DOI 10.1097/BCR.0b013e31823356ce
   Chipp E, 2017, BURNS TRAUMA, V5, DOI 10.1186/s41038-016-0068-2
   CHVAPIL M, 1984, PLAST RECONSTR SURG, V73, P438, DOI 10.1097/00006534-198403000-00018
   Cubison TCS, 2006, BURNS, V32, P992, DOI 10.1016/j.burns.2006.02.007
   Davis SC, 2019, WOUND REPAIR REGEN, V27, P360, DOI 10.1111/wrr.12718
   DEITCH EA, 1983, J TRAUMA, V23, P895, DOI 10.1097/00005373-198310000-00009
   Gacto-Sanchez P, 2017, MED INTENSIVA, V41, P356, DOI [10.1016/j.medine.2017.02.015, 10.1016/j.medin.2017.02.008]
   Gaines C, 2013, BURNS, V39, P311, DOI 10.1016/j.burns.2012.06.011
   Gravante G, 2007, BURNS, V33, P966, DOI 10.1016/j.burns.2007.04.011
   HEIMBACH D, 1992, WORLD J SURG, V16, P10, DOI 10.1007/BF02067108
   Hirth DA, 2012, WOUND REPAIR REGEN, V20, P918, DOI 10.1111/j.1524-475X.2012.00847.x
   Holmes JH, 2019, BURNS, V45, P772, DOI 10.1016/j.burns.2018.11.002
   Holmes JH, 2018, J BURN CARE RES, V39, P694, DOI 10.1093/jbcr/iry029
   Hu Z, 2017, BRIT J SURG, V104, P836, DOI 10.1002/bjs.10508
   Israel JS, 2017, J BURN CARE RES, V38, pE125, DOI 10.1097/BCR.0000000000000475
   KAHN AM, 1979, SCAND J PLAST RECONS, V13, P53, DOI 10.3109/02844317909013020
   Kantak NA, 2017, CLIN PLAST SURG, V44, P671, DOI 10.1016/j.cps.2017.02.023
   Kantak NA, 2016, BURNS, V42, P1623, DOI 10.1016/j.burns.2016.06.011
   Knabl JS, 1999, BURNS, V25, P229, DOI 10.1016/S0305-4179(98)00172-7
   LIMA RENAN VICTOR KÜMPEL SCHMIDT, 2017, Rev. Col. Bras. Cir., V44, P81, DOI [10.1590/0100-69912017001001, 10.1590/0100-69912017001001]
   Mauskar NA, 2013, J BURN CARE RES, V34, P549, DOI 10.1097/BCR.0b013e3182839aca
   Meyerholz DK, 2009, INT J EXP PATHOL, V90, P26, DOI 10.1111/j.1365-2613.2008.00617.x
   Mino MJ, 2013, LAB ANIMAL, V42, P23
   Monstrey S, 2008, BURNS, V34, P761, DOI 10.1016/j.burns.2008.01.009
   MORITZ AR, 1947, AM J PATHOL, V23, P695
   Nosanov LB, 2017, J SURG RES, V216, P185, DOI 10.1016/j.jss.2017.05.004
   Prindeze NJ, 2015, J BURN CARE RES, V36, P626, DOI 10.1097/BCR.0000000000000187
   Rapp SJ, 2020, J BURN CARE RES, V41, P104, DOI 10.1093/jbcr/irz122
   Sheu SY, 2014, BURNS, V40, P1679, DOI 10.1016/j.burns.2014.04.023
   Singer AJ, 2011, J BURN CARE RES, V32, P638, DOI 10.1097/BCR.0b013e31822dc439
   Singer AJ, 2000, ACAD EMERG MED, V7, P1, DOI 10.1111/j.1553-2712.2000.tb01881.x
   Sullivan TP, 2001, WOUND REPAIR REGEN, V9, P66, DOI 10.1046/j.1524-475x.2001.00066.x
   Travis TE, 2015, J BURN CARE RES, V36, pE125, DOI 10.1097/BCR.0000000000000097
   Travis TE, 2014, J BURN CARE RES, V35, pE321, DOI 10.1097/BCR.0000000000000013
   Wang JF, 2000, CONNECT TISSUE RES, V41, P195, DOI 10.3109/03008200009005290
   Watts AMI, 2001, BURNS, V27, P154, DOI 10.1016/S0305-4179(00)00079-6
   Wood FM, 2012, BURNS, V38, P44, DOI 10.1016/j.burns.2011.03.001
NR 43
TC 13
Z9 13
U1 0
U2 5
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0022-4804
EI 1095-8673
J9 J SURG RES
JI J. Surg. Res.
PD NOV
PY 2021
VL 267
BP 182
EP 196
DI 10.1016/j.jss.2021.05.010
EA JUN 2021
PG 15
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA WA1XB
UT WOS:000702685500022
PM 34153561
OA hybrid
DA 2026-07-24
ER

PT J
AU Hajjar, MS
   Atallah, GM
   Oneissi, A
   Beaineh, P
   Abu-Sittah, GS
AF Hajjar, Marwan S.
   Atallah, Georgio M.
   Oneissi, Ahmad
   Beaineh, Paul
   Abu-Sittah, Ghassan S.
TI What is the role of incisional vacuum therapy in challenging spinal
   wounds? A single centre experience
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE diabetes; dressing; incisional vacuum therapy; infection; negative
   pressure wound therapy; spinal surgery; spine; wound; wound
   complications; wound healing
ID SURGICAL SITE INFECTION; ASSISTED CLOSURE; RISK-FACTORS; POSTOPERATIVE
   COMPLICATIONS; EPIDURAL HEMATOMA; LUMBAR SPINE; SURGERY; MANAGEMENT;
   IMPACT
AB Objective: A surgical approach to the treatment of spinal defects and disorders has become more common because of the medical and technological advancements achieved in the last decade. This rising trend in spinal surgeries is associated with adverse events, most notably wound complications. From its introduction, negative pressure wound therapy (NPWT) has proved to be essential in the management of complex wounds and in speeding up wound recovery. The aim of this study is to investigate the use of incisional NPWT in patients undergoing spinal surgery and its role in the prevention of wound complications.
   Method: This study is a retrospective medical chart review conducted on patients who underwent spinal surgery and received incisional vacuum therapy as part of their treatment. The apparatus was applied intraoperatively following the spinal surgery for all patients included in this study. All surgical procedures were conducted between September 2019 and May 2020. Data entry and analysis were performed between September and October 2020.
   Results: A total of five patients' records were reviewed. In our healthcare centre, three patients developed seroma, one developed haematoma, four required revision surgery and one patient required re-operation. There was no wound dehiscence and none of the wounds became infected. Mean length of hospital stay was 11.2 days (standard deviation (SD): 9.5 days) and mean operation time was 333 minutes (SD: 86.4 minutes).
   Conclusion: There is a scarcity of data on the role of incisional vacuum therapy in the prevention of wound complications associated with spine surgeries. Our study showed promising results for the use of incisional NPWT in the management of spinal wounds. Further research is required in order to enhance wound care by exploiting this potentially beneficial approach.
C1 [Hajjar, Marwan S.; Atallah, Georgio M.; Oneissi, Ahmad; Beaineh, Paul] Amer Univ Beirut, Dept Surg, Div Plast Surg, Med Ctr, Beirut, Lebanon.
   [Abu-Sittah, Ghassan S.] Amer Univ Beirut, Global Hlth Inst, Conflict Med Program, Beirut, Lebanon.
C3 American University of Beirut; American University of Beirut
RP Abu-Sittah, GS (通讯作者)，Amer Univ Beirut, Global Hlth Inst, Conflict Med Program, Beirut, Lebanon.
EM Ghassan.s.abusittah@gmail.com
RI Abu-Sittah, Ghassan/AAE-3169-2020
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   Akins PT, 2015, SPINE, V40, P1022, DOI 10.1097/BRS.0000000000000916
   Aono H, 2011, J NEUROSURG-SPINE, V15, P202, DOI 10.3171/2011.3.SPINE10716
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Brown AM, 2020, N Am Spine Soc J, V3
   Chaudhary SB, 2007, J SPINAL CORD MED, V30, P441, DOI 10.1080/10790268.2007.11753476
   Chen F, 2019, MEDICINE, V98, DOI 10.1097/MD.0000000000015126
   Cheng H, 2018, J SURG RES, V229, P134, DOI 10.1016/j.jss.2018.03.022
   Deptula M, 2019, POSTEP DERM ALERGOL, V36, P139, DOI 10.5114/ada.2018.72585
   DEYO RA, 1992, J BONE JOINT SURG AM, V74A, P536, DOI 10.2106/00004623-199274040-00009
   Deyo RA, 2006, CLIN ORTHOP RELAT R, P139, DOI 10.1097/01.blo.0000198726.62514.75
   Deyo RA, 2010, JAMA-J AM MED ASSOC, V303, P1259, DOI 10.1001/jama.2010.338
   Dobran M, 2017, BMJ Case Reports, V2017
   Driver RK, 2016, CUREUS J MED SCIENCE, V8, DOI 10.7759/cureus.903
   Dyck BA, 2019, J NEUROSURG-SPINE, V31, P430, DOI 10.3171/2019.2.SPINE18947
   Epstein Nancy E, 2018, Surg Neurol Int, V9, P251, DOI [10.4103/sni.sni_372_18, 10.4103/sni.sni_372_18]
   Falicov A, 2006, SPINE, V31, P2849, DOI 10.1097/01.brs.0000245838.37817.40
   Foxx KC, 2018, J NEUROSURG-SPINE, V28, P220, DOI 10.3171/2017.5.SPINE17387
   Glennie RA, 2015, J CLIN NEUROSCI, V22, P1081, DOI 10.1016/j.jocn.2015.01.009
   Hardy KL, 2014, AESTHET SURG J, V34, P614, DOI 10.1177/1090820X14528503
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Jiménez-Avíla JM, 2019, CIR CIR, V87, P299, DOI [10.24875/CIRU.19000583, 10.24875/ciru.19000583]
   Kimmell KT, 2015, SPINE, V40, P1836, DOI 10.1097/BRS.0000000000001051
   LIMA RENAN VICTOR KÜMPEL SCHMIDT, 2017, Rev. Col. Bras. Cir., V44, P81, DOI [10.1590/0100-69912017001001, 10.1590/0100-69912017001001]
   Lozano-Balderas G, 2017, AM SURGEON, V83, P512
   Ma ZJ, 2017, INT J MOL MED, V40, P1415, DOI 10.3892/ijmm.2017.3131
   Malhotra A, 2015, INSIGHTS IMAGING, V6, P579, DOI 10.1007/s13244-015-0435-8
   Mancuso CA, 2017, CLIN J PAIN, V33, P93, DOI 10.1097/AJP.0000000000000383
   Martin ET, 2016, INFECT CONT HOSP EP, V37, P88, DOI 10.1017/ice.2015.249
   Mazel C, 2009, ORTHOP CLIN N AM, V40, P75, DOI 10.1016/j.ocl.2008.09.008
   Meloni M, 2015, WORLD J ORTHOP, V6, P387, DOI 10.5312/wjo.v6.i4.387
   Meng F, 2015, J CLIN NEUROSCI, V22, P1862, DOI 10.1016/j.jocn.2015.03.065
   Mithani SK, 2006, NEUROSURG QUART, V16, P9, DOI 10.1097/01.wnq.0000203020.93797.ed
   Nasser R, 2010, J NEUROSURG-SPINE, V13, P144, DOI 10.3171/2010.3.SPINE09369
   Naylor RM, 2020, WORLD NEUROSURG, V137, pE257, DOI 10.1016/j.wneu.2020.01.152
   Nordmeyer M, 2016, INT WOUND J, V13, P1176, DOI 10.1111/iwj.12436
   Patchell RA, 2005, LANCET, V366, P643, DOI 10.1016/S0140-6736(05)66954-1
   Payne Wyatt G, 2008, Eplasty, V8, pe9
   Piper Keaton F, 2017, Surg Neurol Int, V8, P269, DOI [10.4103/sni.sni_306_17, 10.4103/sni.sni_306_17]
   Proietti L, 2013, INDIAN J ORTHOP, V47, P340, DOI 10.4103/0019-5413.114909
   Sabnis AB, 2014, INDIAN J ORTHOP, V48, P127, DOI 10.4103/0019-5413.128740
   Sivasubramaniam V, 2015, BMJ OPEN, V5, DOI 10.1136/bmjopen-2015-009011
   Sudhakaran Sivakumar, 2015, Surg Res Pract, V2015, P284063, DOI [10.1155/2015/284063, 10.1155/2015/284063]
   Swann MC, 2016, BEST PRAC RES-CL ANA, V30, P103, DOI 10.1016/j.bpa.2016.01.002
   ter Gunne AFP, 2009, SPINE, V34, P1422, DOI 10.1097/BRS.0b013e3181a03013
   Theadom A, 2006, TOB CONTROL, V15, P352, DOI 10.1136/tc.2005.015263
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Weidenhamer NK, 2013, TISSUE ENG PART C-ME, V19, P386, DOI [10.1089/ten.tec.2012.0423, 10.1089/ten.TEC.2012.0423]
   Whelan C, 2005, J UROLOGY, V173, P1463, DOI 10.1097/01.ju.0000157339.05939.21
   Wicke C, 2000, ARCH SURG-CHICAGO, V135, P1265, DOI 10.1001/archsurg.135.11.1265
   Yeramaneni S, 2016, CURR REV MUSCULOSKE, V9, P327, DOI 10.1007/s12178-016-9352-9
   Yew A, 2013, J NEUROSURG-SPINE, V19, P297, DOI 10.3171/2013.5.SPINE121028
   Zhou JM, 2020, SPINE, V45, P208, DOI 10.1097/BRS.0000000000003218
NR 53
TC 4
Z9 4
U1 0
U2 3
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD JUN
PY 2021
VL 30
IS 6
BP 476
EP 481
DI 10.12968/jowc.2021.30.6.476
PG 6
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA ST0ZV
UT WOS:000662180700010
PM 34121438
DA 2026-07-24
ER

PT J
AU Chen, RF
   Huang, LS
   Zheng, JB
   Jia, YQ
   Liu, YJ
   Shan, Y
AF Chen Rui-feng
   Huang Li-song
   Zheng Ji-bo
   Jia Yi-qing
   Liu Yu-jie
   Shan Yi
TI Negative pressure wound therapy for serious dog bites of extremities: a
   prospective randomized trial
SO AMERICAN JOURNAL OF EMERGENCY MEDICINE
LA English
DT Article
ID MANAGEMENT; LACERATIONS; CLOSURE
AB Objectives: The objectives were to investigate the emergency treatment of serious dog bite lacerations on limbs and to identify whether negative pressure wound therapy (NPWT) was beneficial in these instances.
   Methods: A total of 580 cases with serious limb lacerations due to dog bites were randomly divided into 2 groups. After thorough debridement, the limblacerations of group A (n=329) were left open. The remaining cases (n=251) were randomly divided into 2 subgroups, group B and group C, which were treated with 125 and 75 mm Hg of continuous negative pressure, respectively. Antibiotics were only used in cases where there were systemic signs of wound infection, and were not given prophylactically. The infection rate, infection time, and healing time were analyzed.
   Results: The wound infection rates of groups A, B, and C were 9.1%, 4.1%, and 3.9%, respectively. The infection times of the 3 groups were 26.3 +/- 11.6, 159.8 +/- 13.4, and 166.4 +/- 16.2 hours, respectively. The recovery times of the infection patients in the 3 groups were 19.2 +/- 4.6, 13.2 +/- 2.1, and 12.7 +/- 2.3 days, respectively, and in the noninfection patients, the recovery times were 15.6 +/- 2.7, 10.1 +/- 2.3, and 10.5 +/- 1.9 days, respectively. In groups B (-125 mm Hg) and C (-75 mm Hg), the infection rate, infection time, and healing time showed no significant differences.
   Conclusion: Patients with serious dog bite laceration on limbs could benefit from NPWT. Compared with the traditional treatment of leaving the wounds open, NPWT reduced the infection rate and shortened recovery time. When NPWT was performed, low negative pressure (-75 mm Hg) had the same positive effects as high pressure (-125 mm Hg). Prophylactic antibiotics administration is not recommended for treating this kind of laceration.
   Level of evidence: Therapeutic/care management, level II. (C) 2016 Elsevier Inc. All rights reserved.
C1 [Chen Rui-feng; Huang Li-song; Zheng Ji-bo; Jia Yi-qing; Liu Yu-jie; Shan Yi] China Liberat Army, Dept Emergency, Naval Gen Hosp, Beijing 100048, Peoples R China.
RP Shan, Y (通讯作者)，China Liberat Army, Dept Emergency, Naval Gen Hosp, Beijing 100048, Peoples R China.
EM cc_rrff@126.com; navyhuang76@163.com; hjzyyjzk@126.com;
   yiqing_1983@126.com; ff2061222@163.com; shanyi_navy@126.com
CR A Novak, 2014, Open Orthop J, V8, P168, DOI 10.2174/1874325001408010168
   Abrahamian, 2000, Curr Infect Dis Rep, V2, P446, DOI 10.1007/s11908-000-0075-z
   Anderson PJ, 1997, INJURY, V28, P717, DOI 10.1016/S0020-1383(97)82147-X
   [Anonymous], 2010, Wkly Epidemiol Rec, V85, P309, DOI DOI 10.1016/J.VACCINE.2010.08.082
   [Anonymous], 2001, Crossing the Qulity Chasm: a New Health System for the 21st Century Shaping the Future for Health, P1
   ARMSTRONG JA, 1964, APPL MICROBIOL, V12, P132, DOI 10.1128/AEM.12.2.132-137.1964
   Borgquist O, 2011, PLAST RECONSTR SURG, V127, P551, DOI 10.1097/PRS.0b013e3181fed52a
   Capellan O, 2003, EMERG MED CLIN N AM, V21, P205, DOI 10.1016/S0733-8627(02)00087-1
   Chaudhry MA, 2004, EUR J EMERG MED, V11, P313, DOI 10.1097/00063110-200412000-00003
   Chen RF, 2012, GUIDE CHINA MED, V5, P401
   Chen RF, 2011, CHINA J EMERGENCY RE, V6, P21
   DEAN DJ, 1963, B WORLD HEALTH ORGAN, V28, P477
   Dendle C, 2009, AUST FAM PHYSICIAN, V38, P868
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Fleisher GR, 1999, NEW ENGL J MED, V340, P138, DOI 10.1056/NEJM199901143400210
   Garbutt F, 2004, EMERG MED J, V21, P589, DOI 10.1136/emj.2004.017962
   Garcia V F, 1997, Pediatr Rev, V18, P127, DOI 10.1542/pir.18-4-127
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   GOLDSTEIN EJC, 1978, J CLIN MICROBIOL, V8, P667
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Jofré M. Leonor, 2006, Rev. chil. infectol., V23, P20
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P601, DOI 10.1097/PRS.0b013e318196b97b
   Kaufman-Rivi D, 2013, ADV SKIN WOUND CARE, V26, P311, DOI 10.1097/01.ASW.0000431962.90766.2e
   Kim PJ, 2013, PLAST RECONSTR SURG, V132, P1569, DOI 10.1097/PRS.0b013e3182a80586
   Lavery LA, 2014, PLAST RECONSTR SURG, V133, P722, DOI 10.1097/01.prs.0000438046.83515.6a
   MAIMARIS C, 1988, ARCH EMERG MED, V5, P156
   Masden D, 2012, ANN SURG, V255, P1043, DOI 10.1097/SLA.0b013e3182501bae
   Medeiros I, 2001, COCHRANE DB SYST REV, V2
   Morgan M, 2007, BMJ-BRIT MED J, V334, P413, DOI 10.1136/bmj.39105.659919.BE
   Paschos NK, 2014, INJURY, V45, P237, DOI 10.1016/j.injury.2013.07.010
   Peinemann F, 2011, DTSCH ARZTEBL INT, V108, P381, DOI 10.3238/arztebl.2011.0381
   Roberts DJ, 2013, TRIALS, V14, DOI 10.1186/1745-6215-14-141
   Smith MR, 2003, EMERG MED J, V20, P253, DOI 10.1136/emj.20.3.253
   Stefanopoulos Panayotis, 2004, Acta Orthop Belg, V70, P1
   Talan DA, 1999, NEW ENGL J MED, V340, P85, DOI 10.1056/NEJM199901143400202
   Taplitz RA, 2004, POSTGRAD MED, V116, P49, DOI 10.3810/pgm.2004.08.1572
   WHO, 2013, WHO TECH REP SER, V982, P1
NR 37
TC 11
Z9 11
U1 0
U2 10
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0735-6757
EI 1532-8171
J9 AM J EMERG MED
JI Am. J. Emerg. Med.
PD JUN
PY 2016
VL 34
IS 6
BP 1006
EP 1010
DI 10.1016/j.ajem.2016.02.043
PG 5
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA DN8OO
UT WOS:000377338700013
PM 26964825
DA 2026-07-24
ER

PT J
AU Song, YY
   Liu, LW
   Chu, WL
   Shen, CN
AF Song, Yaoyao
   Liu, Liwei
   Chu, Wanli
   Shen, Chuanan
TI PRP-NPWT in DSWI with osteomyelitis: sternal stability and albumin
   predict healing failure
SO EUROPEAN JOURNAL OF MEDICAL RESEARCH
LA English
DT Article
DE Deep sternal wound infection; Osteomyelitis; Platelet-rich plasma;
   Negative-pressure wound therapy; Risk factors
ID PLATELET-RICH PLASMA; WOUND-INFECTION; PREVENTION; MANAGEMENT; RISK
AB Background Deep sternal wound infection with osteomyelitis (DSWI-OM) is a severe complication after median sternotomy. This study aimed to identify key determinants of wound healing after initial combined platelet-rich plasma (PRP) and negative-pressure wound therapy (NPWT) in DSWI-OM patients, to guide individualized management. Methods In a single-center retrospective cohort, 75 DSWI-OM patients treated with PRP-NPWT (2013-2021) were stratified by healing status at 2 weeks into Healed (n = 33) and Nonhealed (n = 42) groups. Univariate and multivariable logistic regression analyses identified risk factors from baseline characteristics, wound-specific factors (e.g., debridement history), and laboratory parameters. ROC curves established cut-off values. A novel sternal stability classification (Type A: stable, B: loosened, C: defective) integrated anatomical severity. Results The primary closure failure rate was significantly higher in DSWI-OM than DSWI-alone patients (56.0% vs 22.5% P = 0.0006). Multivariable analysis identified prior debridement (OR 3.648, 95% CI 1.097-12.126) and serum albumin level (analyzed as a continuous variable, OR 0.838 per 1 g/L increase, 95% CI 0.746-0.941) as independent risk factors (all P < 0.05). In addition, an albumin threshold of < 31.5 g/L was predictive of failure (AUC 0.763). Sternal stability grading strongly correlated with healing (Type A: 42.4% vs Type C: 30.3% P = 0.037). Failed pre-admission debridement was associated with greater sternal instability/defects (P = 0.043). Conclusions Sternal structural integrity and nutritional status are critical for PRP-NPWT success in DSWI-OM. Integrating sternal stability classification and an albumin threshold (>= 31.5 g/L) into preoperative assessment can optimize timing and procedure selection, potentially avoiding futile primary closure in high-risk patients. These findings require prospective validation.
C1 [Song, Yaoyao; Liu, Liwei; Chu, Wanli; Shen, Chuanan] Chinese Peoples Liberat Army Gen Hosp, Dept Burns & Plast Surg, Med Ctr 4, 51 Fucheng Rd, Beijing 100048, Peoples R China.
C3 Chinese People's Liberation Army General Hospital
RP Shen, CN (通讯作者)，Chinese Peoples Liberat Army Gen Hosp, Dept Burns & Plast Surg, Med Ctr 4, 51 Fucheng Rd, Beijing 100048, Peoples R China.
EM shenchuanan@301hospital.com.cn
FX Not applicable.
CR Al-Ebrahim KE, 2020, HEART SURG FORUM, V23, pE652, DOI [10.1532/hsf.3153Prevention, 10.1532/hsf.3153]
   Al-Ebrahim KE, 2020, HEART SURG FORUM, V23, pE281, DOI 10.1532/hsf.2805
   An WJ, 2021, FRONT SURG, V8, DOI 10.3389/fsurg.2021.621559
   Braun C, 2023, J CLIN MED, V12, DOI 10.3390/jcm12134271
   Chan PG, 2020, J CARDIAC SURG, V35, P549, DOI 10.1111/jocs.14415
   Cotogni Paolo, 2015, World J Crit Care Med, V4, P265, DOI [10.5492/wjccm.v4.i4.265, 10.5492/wjccm.v4.i4.265]
   Dai CY, 2013, ANN THORAC SURG, V95, P1938, DOI 10.1016/j.athoracsur.2012.12.038
   Deo SV, 2015, INT J SURG, V16, P163, DOI 10.1016/j.ijsu.2015.01.008
   Elassal AA, 2020, HEART SURG FORUM, V23, pE76, DOI [10.1532/hsf.2649, 10.1532/114:26,49]
   Enginoev S, 2022, BRAZ J CARDIOV SURG, V37, P13, DOI 10.21470/1678-9741-2020-0444
   Furui M, 2022, INT HEART J, V63, P426, DOI 10.1536/ihj.21-464
   Gatti G, 2015, EUR J CARDIO-THORAC, V48, P115, DOI 10.1093/ejcts/ezu360
   Houwing RH, 2003, CLIN NUTR, V22, P401, DOI 10.1016/S0261-5614(03)00039-6
   Kumar U, 2024, CUREUS J MED SCIENCE, V16, DOI 10.7759/cureus.59719
   Li WD, 2025, KAOHSIUNG J MED SCI, V41, DOI 10.1002/kjm2.12940
   Pettinari M, 2015, EUR J CARDIO-THORAC, V47, P703, DOI 10.1093/ejcts/ezu206
   Roffi A, 2017, INT ORTHOP, V41, P221, DOI 10.1007/s00264-016-3342-9
   Schiraldi L, 2019, ARCH PLAST SURG-APS, V46, P291, DOI 10.5999/aps.2018.01151
   Siddiqui H, 2026, Mymensingh Med J, V35, P494
   Song YY, 2023, INT WOUND J, V20, P3457, DOI 10.1111/iwj.14216
   Song YY, 2023, J CARDIOTHORAC SURG, V18, DOI 10.1186/s13019-023-02228-y
   Verma R, 2023, CELL TISSUE BANK, V24, P285, DOI 10.1007/s10561-022-10039-z
   Wei SK, 2021, ACTA BIOMATER, V124, P205, DOI 10.1016/j.actbio.2021.01.046
   Yuan CR, 2025, BIOMEDICINES, V13, DOI 10.3390/biomedicines13112832
   Zhang JN, 2022, FRONT IMMUNOL, V13, DOI 10.3389/fimmu.2022.957407
   Zhong YX, 2023, J MYCOL MED, V33, DOI 10.1016/j.mycmed.2022.101330
NR 26
TC 0
Z9 0
U1 0
U2 0
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 0949-2321
EI 2047-783X
J9 EUR J MED RES
JI Eur. J. Med. Res.
PD MAY 13
PY 2026
VL 31
IS 1
AR 971
DI 10.1186/s40001-026-04573-9
EA MAY 2026
PG 11
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA KW7SG
UT WOS:001817440600002
OA gold
DA 2026-07-24
ER

PT J
AU Scarpa, C
   Grigatti, M
   Rizzato, S
   Crema, A
   Vindigni, V
   Bassetto, F
AF Scarpa, Carlotta
   Grigatti, Martina
   Rizzato, Sandro
   Crema, Alberto
   Vindigni, Vincenzo
   Bassetto, Franco
TI Novel Foam Dressing With Through Holes and Negative Pressure Wound
   Therapy With Instillation and Dwell Time: A Retrospective Cohort Study
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE negative pressure wound therapy; NPWTi-d; NPWT with instillation and
   dwell time; foam dressing; ROCF-CC; ROCF-V
AB Background. NPWTi-d of a topical wound solution has been shown to benefit healing in a variety of wound types. This therapy has traditionally been applied via a standard ROCF-V. In 2017, a new ROCF-CC was introduced at the practice of the authors of the current manuscript for adjunctive management of patients with wounds with thick exudate and/or nonviable tissue and in cases in which surgical debridement is not available or not appropriate. Objective. To compare the efficacy of NPWTi-d with ROCF-CC dressing (treatment) vs NPWTi-d with ROCF-V dressing (control). Materials and Methods. An observational retrospective cohort study of hospital records of patients with VLUs treated with NPWTi-d who received ROCF-CC dressings (n = 11) vs standard ROCF-V dressings (n = 11) was conducted. NPWTi-d was chosen to promote wound healing in VLUs that were not fully responsive to advanced dressings and/or compression bandage. Solution dwell time was 10 minutes, followed by 2.5 -hour NPWT cycles at -125 mm Hg. Dressings were changed every 72 hours. Results. Overall, mean +/- SD duration of therapy and hospital length of stay were shorter in the treatment group vs the control group (duration of therapy, 8.63 days +/- 7.05 vs 11.72 days +/- 17.41, respectively; P = .05, and length of stay, 9.9 days +/- 2.98 vs 12.81 days +/- 4.26, respectively; P = .08), but these differences were not statistically significant. Mean wound area reduction was greater in the treatment group than in the control group (14.63 cm 2 +/- 13.24 and 10.72 cm 2 +/- 14.06, respectively; P = .51), but this was not significant. Conclusion. ROCF-CC dressings were a useful tool in assisting wound bed preparation and reducing time to skin graft closure in this series of complex VLUs.
C1 [Scarpa, Carlotta; Grigatti, Martina; Rizzato, Sandro; Crema, Alberto; Vindigni, Vincenzo; Bassetto, Franco] Univ Padua, Plast Surg Inst, Padua, Italy.
   [Scarpa, Carlotta] Inst Plast Surg, Neurosci, Via Giustinani 2, I-35100 Padua, Italy.
C3 University of Padua
RP Scarpa, C (通讯作者)，Inst Plast Surg, Neurosci, Via Giustinani 2, I-35100 Padua, Italy.
EM carlotta.scarpa@unipd.it
RI Vindigni, Vincenzo/K-5059-2016; Scarpa, Carlotta/HJG-7233-2022
CR Bennison LR, 2017, WOUND PRACT RES, V25, P63
   Faust E, 2021, PLAST RECONSTR SURG, V147, p16S, DOI 10.1097/PRS.0000000000007607
   Fernandez L, 2017, Journal of Trauma & Treatment, V06, DOI [10.4172/2167-1222.1000410, 10.4172/2167-1222.1000410, DOI 10.4172/2167-1222.1000410]
   Gabriel Allen, 2014, Plast Surg Nurs, V34, P88, DOI 10.1097/PSN.0000000000000033
   Galea E., 2016, Wounds Middle East, V3, P34
   Greener B, 2005, J Wound Care, V14, P59
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Kairinos N, 2010, J PLAST RECONSTR AES, V63, P174, DOI 10.1016/j.bjps.2008.08.037
   Kim PJ, 2020, INT WOUND J, V17, P174, DOI 10.1111/iwj.13254
   Kim PJ, 2018, WOUNDS, pS1
   Kramer A, 2018, SKIN PHARMACOL PHYS, V31, P28, DOI 10.1159/000481545
   McElroy EF, 2019, INT WOUND J, V16, P781, DOI 10.1111/iwj.13097
   Miller Christine, 2012, J Am Coll Clin Wound Spec, V4, P61, DOI 10.1016/j.jccw.2013.11.002
   Panayi AC, 2017, World Journal of Dermatology, V6, P1, DOI [10.5314/wjd.v6.i1.1, 10.5314/wjd.v6.i1.1, DOI 10.5314/WJD.V6.I1.1]
   Téot L, 2017, INT WOUND J, V14, P842, DOI 10.1111/iwj.12719
NR 15
TC 3
Z9 3
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD MAR
PY 2024
VL 36
IS 3
BP 67
EP 72
DI 10.25270/wnds/23081
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA QM3U1
UT WOS:001221259200002
PM 38684120
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Csiszkó, A
   Balog, K
   Godó, ZA
   Juhász, G
   Peto, K
   Deák, A
   Berhés, M
   Németh, N
   Bodnár, Z
   Szentkereszty, Z
AF Csiszko, Adrienn
   Balog, Klaudia
   Godo, Zoltan Attila
   Juhasz, Gyula
   Peto, Katalin
   Deak, Adam
   Berhes, Mariann
   Nemeth, Norbert
   Bodnar, Zsolt
   Szentkereszty, Zsolt
TI Pressure Distribution during Negative Pressure Wound Therapy of
   Experimental Abdominal Compartment Syndrome in a Porcine Model
SO SENSORS
LA English
DT Article
DE intra-abdominal pressure; abdominal compartment syndrome; pressure
   sensor; negative ressure wound therapy; open abdomen
ID MICROVASCULAR BLOOD-FLOW; OPEN ABDOMEN; INTRAABDOMINAL PRESSURE; CLOSURE
   TECHNIQUES; INTESTINAL WALL; ANIMAL-MODEL; HYPERTENSION; DECOMPRESSION;
   MANAGEMENT
AB (1) Introduction: Negative pressure wound therapy (NPWT) is a frequently applied open abdomen (OA) treatment. There are only a few experimental data supporting this method and describing the optimal settings and pressure distribution in the abdominal cavity during this procedure. The aim of our study was to evaluate pressure values at different points in the abdominal cavity during NPWT in experimental abdominal compartment syndrome (ACS) animal model; (2) Methods: In this study (permission Nr. 13/2014/UDCAW), 27 Hungahib pigs (15.4-20.2 kg) were operated on. ACS was generated by implanting a plastic bag in the abdomen through mini-laparotomy and filled with 2100-3300 mL saline solution (37 degrees C) to an intraabdominal pressure (IAP) of 30 mmHg. After 3 h, NPWT (Vivano Med (R) Abdominal Kit, Paul Hartmann AG, Germany) or a Bogota bag was applied. The NPWT group was divided into -50, -100 and -150 mmHg suction groups. Pressure distribution to the abdominal cavity was monitored at 6 different points of the abdomen via a multichannel pressure monitoring system; (3) Results: The absolute pressure levels were significantly higher above than below the protective layer. The values of the pressure were similar in the midline and laterally. Amongst the bowels, the pressure values changed periodically between 0 and -12 mmHg which might be caused by peristaltic movements; (4) Conclusions: The porcine model of the present study seems to be well applicable for investigating ACS and NPWT. It was possible to provide valuable information for clinicians. The pressure was well distributed by the protective layer to the lateral parts of the abdomen and this phenomenon did not change considerably during the therapy.
C1 [Csiszko, Adrienn; Balog, Klaudia; Szentkereszty, Zsolt] Univ Debrecen, Fac Med, Inst Surg, Egyet Ter 1, H-4032 Debrecen, Hungary.
   [Godo, Zoltan Attila; Juhasz, Gyula] Univ Debrecen, Fac Informat, Dept Informat Technol, Egyet Ter 1, H-4032 Debrecen, Hungary.
   [Peto, Katalin; Deak, Adam; Nemeth, Norbert] Univ Debrecen, Fac Med, Dept Operat Tech & Surg Res, Egyet Ter 1, H-4032 Debrecen, Hungary.
   [Berhes, Mariann] Univ Debrecen, Fac Med, Dept Anaesthesiol & Intens Care, Egyet Ter 1, H-4032 Debrecen, Hungary.
   [Bodnar, Zsolt] Letterkenny Univ Hosp, Dept Surg, Letterkenny F92VX8D, Ireland.
C3 University of Debrecen; University of Debrecen; University of Debrecen;
   University of Debrecen
RP Bodnár, Z (通讯作者)，Letterkenny Univ Hosp, Dept Surg, Letterkenny F92VX8D, Ireland.
EM csiszko@gmail.com; klaudia.balog@live.com; magortaltos@gmail.com;
   gyuszi32@gmail.com; kpeto@med.unideb.hu; deak.adam@med.unideb.hu;
   bermarjan@yahoo.co.uk; nemeth@med.unideb.hu; drbozsolt@gmail.com;
   szentkerzs@gmail.com
RI Petö, Katalin/IWD-5161-2023; Nemeth, Norbert/AAX-8704-2020
OI Nemeth, Norbert/0000-0002-1162-3778; Deak, Adam/0000-0001-7516-3152
CR Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
   Benninger E, 2009, J TRAUMA, V66, P1118, DOI 10.1097/TA.0b013e3181820d94
   Bjarnason T, 2011, WORLD J SURG, V35, P917, DOI 10.1007/s00268-010-0937-y
   Bruhin A, 2014, INT J SURG, V12, P1105, DOI 10.1016/j.ijsu.2014.08.396
   Coccolini F, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0026-5
   Correa-Martín L, 2013, J SURG RES, V184, P1028, DOI 10.1016/j.jss.2013.04.041
   Demetriades D, 2014, SURG CLIN N AM, V94, P131, DOI 10.1016/j.suc.2013.10.010
   Elvevoll Bjorg, 2014, BMC Res Notes, V7, P738, DOI 10.1186/1756-0500-7-738
   Hlebowicz J, 2012, INT J COLORECTAL DIS, V27, P397, DOI 10.1007/s00384-011-1317-2
   Huang Q, 2016, GASTROENT RES PRACT, V2016, DOI 10.1155/2016/2073260
   Ke L, 2013, J TRAUMA ACUTE CARE, V74, P1060, DOI 10.1097/TA.0b013e318283d927
   Ke L, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0033125
   Kirkpatrick AW, 2015, ANAESTH INTENSIVE TH, V47, pS63, DOI 10.5603/AIT.a2015.0081
   Kirkpatrick AW, 2009, CRIT CARE MED, V37, P591, DOI 10.1097/CCM.0b013e3181954491
   Lessing MC, 2013, EPLASTY, V13, pe51
   Lindstedt S, 2015, INT WOUND J, V12, P83, DOI 10.1111/iwj.12056
   Olofsson PH, 2009, CRIT CARE MED, V37, P230, DOI 10.1097/CCM.0b013e318192ff51
   Otto J, 2010, SHOCK, V33, P639, DOI 10.1097/SHK.0b013e3181cb8be0
   Schachtrupp A, 2007, ACTA CLIN BELG, V62, P225, DOI 10.1179/acb.2007.62.s1.031
   Skoog P, 2014, EUR J VASC ENDOVASC, V47, P402, DOI 10.1016/j.ejvs.2014.01.007
   Suh H., 2014, ANN PLAST SURG, V76, P717
   Yoshino O, 2012, INJURY, V43, P169, DOI 10.1016/j.injury.2011.04.011
NR 22
TC 4
Z9 6
U1 0
U2 3
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
SN 1424-8220
J9 SENSORS-BASEL
JI Sensors
PD MAR
PY 2018
VL 18
IS 3
AR 897
DI 10.3390/s18030897
PG 11
WC Chemistry, Analytical; Engineering, Electrical & Electronic; Instruments
   & Instrumentation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Chemistry; Engineering; Instruments & Instrumentation
GA GB1IU
UT WOS:000428805300218
PM 29562626
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Su, HY
   Chew, KY
   Graves, N
   Ou, HT
AF Su, Hsuan-Yu
   Chew, Khong-Yik
   Graves, Nicholas
   Ou, Huang-Tz
TI Cost-effectiveness of ON101 with general wound care for diabetic foot
   ulcers among patients with type 2 diabetes in Singapore: Analysis of a
   multi-ethnic country in Asia
SO DIABETES OBESITY & METABOLISM
LA English
DT Article
DE diabetic foot ulcer; economic evaluation; incremental cost-effectiveness
   ratio; negative pressure wound therapy; wound healing
ID BURDEN
AB Aims Diabetic foot ulcers (DFUs) impose a vast health and economic burden on individuals and healthcare systems globally. We assessed the cost-effectiveness of adding ON101, a novel treatment for accelerating wound healing, to general wound care (GWC) versus GWC alone for DFUs in Singapore, a multi-ethnic country with increasing DFU prevalence in a growing type 2 diabetes population. Materials and MethodsA Markov model was utilized to estimate the healthcare costs and quality-adjusted life years (QALYs) over 5 years from a healthcare sector perspective. Model inputs were mainly derived from the Singapore Wound Registry and published literature. The primary outcome was the incremental cost-effectiveness ratio (ICER). Subgroup analyses stratified by clinically important DFU conditions and scenario analyses were conducted to confirm the study's robustness. Results Compared to GWC alone, adding ON101 yielded greater QALY gained (i.e., 0.15) and lower healthcare costs (i.e., -US$16237) for patients with DFUs. Remarkable cost-savings from the use of ON101 with GWC were observed for patients with complex DFUs, namely ICERs of -US$161 963, -US$181 726 and -US$199 130 per QALY gained for cases with HbA1c >= 9%, ulcer duration >6 months and ulcer size >5 cm(2), respectively. Scenario analysis comparing ON101 with GWC to negative pressure wound therapy with GWC yielded an ICER of -US$677 243 per QALY gained. Conclusions Combining ON101 with GWC versus GWC alone was highly cost-effective for DFUs in Singapore. Also, the economic results for complex DFU cases underscore the value of ON101 in addressing DFU treatment challenges for managing complex cases, offering cost-savings alongside clinical benefits.
C1 [Su, Hsuan-Yu; Ou, Huang-Tz] Natl Cheng Kung Univ, Inst Clin Pharm & Pharmaceut Sci, Coll Med, Univ Rd, Tainan 701, Taiwan.
   [Chew, Khong-Yik] Singapore Gen Hosp, Dept Plast Reconstruct & Aesthet Surg, Singapore, Singapore.
   [Graves, Nicholas] Duke NUS Med Sch, Hlth Serv & Syst Res, Singapore, Singapore.
   [Ou, Huang-Tz] Natl Cheng Kung Univ, Coll Med, Dept Pharm, Tainan, Taiwan.
C3 National Cheng Kung University; Singapore General Hospital; National
   University of Singapore; National Cheng Kung University
RP Ou, HT (通讯作者)，Natl Cheng Kung Univ, Inst Clin Pharm & Pharmaceut Sci, Coll Med, Univ Rd, Tainan 701, Taiwan.; Chew, KY (通讯作者)，Singapore Gen Hosp, Dept Plast Reconstruct & Aesthet Surg, Outram Rd, Singapore 169608, Singapore.
EM chew.khong.yik@singhealth.com.sg; huangtz@mail.ncku.edu.tw
RI Ou, Huang-Tz/AGO-0498-2022
FU Ministry of Science and Technology, Taiwan [MOST
   112-2628-B-006-008-MY3]; Ministry of Science and Technology in Taiwan
FX The authors acknowledge funding from the Ministry of Science and
   Technology in Taiwan (grant MOST 112-2628-B-006-008-MY3) (Huang-Tz Ou).
CR Agency for Care Effectiveness, 2023, Drug and vaccine evaluation methods and process guide
   Agency for Care Effectiveness, NEGATIVE PRESSURE WO
   Armstrong DG, 2023, JAMA-J AM MED ASSOC, V330, P62, DOI 10.1001/jama.2023.10578
   Bishnoi P, 2025, INT WOUND J, V22, DOI [10.1111/iwj.70146, 10.1111/iwj.70146]
   Chang SC, 2025, ADV WOUND CARE, V14, P381, DOI 10.1089/wound.2023.0167
   Guest JF, 2018, INT WOUND J, V15, P43, DOI 10.1111/iwj.12816
   Guo SB, 2025, LANCET ONCOL, V26, pe126, DOI 10.1016/S1470-2045(25)00008-7
   Guo SB, 2024, MOL CANCER, V23, DOI 10.1186/s12943-024-02140-6
   Huang YY, 2021, JAMA NETW OPEN, V4, DOI 10.1001/jamanetworkopen.2021.22607
   Huang ZH, 2019, INT WOUND J, V16, P1373, DOI 10.1111/iwj.13200
   Husereau D, 2022, BMJ-BRIT MED J, V376, DOI 10.1136/bmj-2021-067975
   International Diabetes Federation, 2022, IDF DIAB FOOT REP
   Ji SZ, 2021, BURNS TRAUMA, V9, DOI 10.1093/burnst/tkab018
   Liu ZM, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD010318.pub3
   Lo ZJ, 2023, INT WOUND J, V20, P1609, DOI 10.1111/iwj.14016
   Low S, 2016, DIABETES RES CLIN PR, V111, P83, DOI 10.1016/j.diabres.2015.09.019
   Lu QW, 2021, DIABET METAB SYND OB, V14, P2019, DOI 10.2147/DMSO.S307815
   Maunoury F, 2021, PLOS ONE, V16, DOI 10.1371/journal.pone.0245652
   McDermott K, 2023, DIABETES CARE, V46, P209, DOI 10.2337/dci22-0043
   Riandini T, 2021, DIABETOLOGIA, V64, P1538, DOI [10.1007/s00125-021-05441-3, 10.1007/s00125-021-05441-31]
   Rice JB, 2014, DIABETES CARE, V37, P651, DOI 10.2337/dc13-2176
   Ruggeri M, 2015, VALUE HEALTH, V18, P709, DOI 10.1016/j.jval.2015.03.1795
   Russo S, 2025, CLINICOECONOMIC OUTC, V17, P157, DOI 10.2147/CEOR.S496616
   Sanders GD, 2019, JAMA-J AM MED ASSOC, V321, P1400, DOI 10.1001/jama.2019.1265
   Schaper NC, 2024, DIABETES-METAB RES, V40, DOI 10.1002/dmrr.3657
   Seah JYH, 2023, BMJ OPEN DIAB RES CA, V11, DOI 10.1136/bmjdrc-2023-003385
   Smart Wealth, 2024, MEDICAL INFLATION RA
   Su HY, 2023, JAMA NETW OPEN, V6, DOI 10.1001/jamanetworkopen.2022.50639
   Sun H, 2022, DIABETES RES CLIN PR, V183, DOI 10.1016/j.diabres.2021.109119
   Tan JK, 2022, PLOS ONE, V17, DOI 10.1371/journal.pone.0275920
   Viswambaram A, 2020, VALUE HEALTH REG ISS, V22, pS72, DOI [10.1016/j.vhri.2020.07.378, 10.1016/j.vhri.2020.07.378, DOI 10.1016/J.VHRI.2020.07.378]
   Woods TJ, 2020, PLOS ONE, V15, DOI 10.1371/journal.pone.0232395
NR 32
TC 3
Z9 3
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1462-8902
EI 1463-1326
J9 DIABETES OBES METAB
JI Diabetes Obes. Metab.
PD AUG
PY 2025
VL 27
IS 8
BP 4344
EP 4353
DI 10.1111/dom.16473
EA MAY 2025
PG 10
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA 4PI4S
UT WOS:001491975400001
PM 40396474
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Wang, YF
   Alnumay, A
   Paradis, T
   Beckett, A
   Fata, P
   Khwaja, K
   Razek, T
   Grushka, J
   Deckelbaum, DL
AF Wang, Yifan
   Alnumay, Abdulaziz
   Paradis, Tiffany
   Beckett, Andrew
   Fata, Paola
   Khwaja, Kosar
   Razek, Tarek
   Grushka, Jeremy
   Deckelbaum, Dan L.
TI Management of Open Abdomen After Trauma Laparotomy: A Comparative
   Analysis of Dynamic Fascial Traction and Negative Pressure Wound Therapy
   Systems
SO WORLD JOURNAL OF SURGERY
LA English
DT Article
ID OPEN ABDOMINAL WOUNDS; DAMAGE-CONTROL; TEMPORARY CLOSURE; VACUUM;
   FISTULA; SURGERY
AB Background Management of the post-traumatic open abdomen (OA) using negative pressure wound therapy (NPWT) alone is associated with low rates of primary fascial closure. The abdominal reapproximation anchor (ABRA) system exerts dynamic medial fascial traction and may work synergistically with NPWT to facilitate primary fascial closure.
   Methods Patients with an OA following trauma laparotomy between 2009 and 2018 were identified from a prospectively maintained institutional database. Patients treated with ABRA in conjunction with NPWT (ABRA) versus NPWT alone (NPWT) were compared in terms of primary fascial closure rate, number of surgeries to closure, tracheostomy duration, length of stay and incidence of entero-atmospheric fistula. Multivariable linear regression was performed to identify predictors of tracheostomy duration.
   Results We identified 48 patients [ABRA, 12 and NPWT, 36]. The ABRA group was significantly younger (25 vs. 37 years, p=0.027) and included a lower proportion of males (58% vs. 89%, p=0.032). Groups were similar with respect to the incidence of hollow viscus injury, injury severity score and abdominal abbreviated injury score. Compared to the NPWT group, the ABRA group had a significantly higher rate of primary fascial closure (100% vs. 28%, p<0.001), fewer surgeries to abdominal closure (2 vs. 2.5, p=0.023) and shorter duration of tracheostomy (15.5 vs. 36 days, p=0.008). There were no differences in length of stay or incidence of entero-atmospheric fistula. On multivariable linear regression, ABRA placement was an independent predictor of shorter tracheostomy duration, after adjusting for covariates (beta=-0.294, p=0.036).
   Conclusion For the post-traumatic OA, ABRA coupled with NPWT achieves a higher rate of primary fascial closure compared to NPWT alone, while requiring fewer surgeries and a shorter duration of tracheostomy.
C1 [Wang, Yifan; Alnumay, Abdulaziz; Paradis, Tiffany; Beckett, Andrew; Fata, Paola; Khwaja, Kosar; Razek, Tarek; Grushka, Jeremy; Deckelbaum, Dan L.] McGill Univ, Hlth Ctr, Div Trauma Surg, 1650 Cedar Ave,L9-411, Montreal, PQ H3G 1A4, Canada.
   [Razek, Tarek; Deckelbaum, Dan L.] McGill Univ, Ctr Global Surg, Montreal, PQ, Canada.
C3 McGill University; McGill University
RP Deckelbaum, DL (通讯作者)，McGill Univ, Hlth Ctr, Div Trauma Surg, 1650 Cedar Ave,L9-411, Montreal, PQ H3G 1A4, Canada.; Deckelbaum, DL (通讯作者)，McGill Univ, Ctr Global Surg, Montreal, PQ, Canada.
EM dan.deckelbaum@mcgill.ca
RI Alnumay, Abdulaziz/MSZ-2173-2025
OI Alnumay, Abdulaziz/0000-0003-1303-4878; Wang, Yifan/0000-0003-2821-1953
CR BAKER SP, 1974, J TRAUMA, V14, P187, DOI 10.1097/00005373-197403000-00001
   Bradley MJ, 2013, JAMA SURG, V148, P947, DOI 10.1001/jamasurg.2013.2514
   BROCK WB, 1995, AM SURGEON, V61, P30
   Cheatham ML, 2013, WORLD J SURG, V37, P2018, DOI 10.1007/s00268-013-2080-z
   Cirocchi R, 2016, J TRAUMA ACUTE CARE, V81, P575, DOI 10.1097/TA.0000000000001126
   Coccolini F, 2019, INJURY, V50, P160, DOI 10.1016/j.injury.2018.09.040
   Coccolini F, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0123-8
   Desai NK, 2016, ANN MED SURG, V7, P14, DOI 10.1016/j.amsu.2016.02.026
   Haddock C, 2013, AM J SURG, V205, P528, DOI 10.1016/j.amjsurg.2013.01.028
   Hatch QM, 2011, J TRAUMA, V71, P1503, DOI 10.1097/TA.0b013e31823cd78d
   Isik A, 2016, GAZI MED J, V27, P19, DOI 10.12996/gmj.2016.06
   Kritayakirana Kritaya, 2010, J Emerg Trauma Shock, V3, P118, DOI 10.4103/0974-2700.62106
   Lee JC, 2006, CURR OPIN CRIT CARE, V12, P346, DOI 10.1097/01.ccx.0000235213.63988.9a
   Lynch AC, 2004, ANN SURG, V240, P825, DOI 10.1097/01.sla.0000143895.17811.e3
   Mattox KL, 1997, SURG CLIN N AM, V77, P753, DOI 10.1016/S0039-6109(05)70581-8
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   MORRIS JA, 1993, ANN SURG, V217, P576, DOI 10.1097/00000658-199305010-00019
   Mukhi AN, 2014, CAN J SURG, V57, P314, DOI 10.1503/cjs.026613
   Nieuwenhuizen J, 2007, SCAND J SURG, V96, P293, DOI 10.1177/145749690709600406
   Olona C, 2015, HERNIA, V19, P323, DOI 10.1007/s10029-014-1253-5
   Porter ME, 2010, NEW ENGL J MED, V363, P2477, DOI 10.1056/NEJMp1011024
   Rasilainen SK, 2012, BRIT J SURG, V99, P1725, DOI 10.1002/bjs.8914
   Reimer MW, 2008, CAN J SURG, V51, P209
   Ribeiro MAF, 2016, WORLD J GASTRO SURG, V8, P590, DOI 10.4240/wjgs.v8.i8.590
   Richter S, 2013, GASTROENT RES PRACT, V2013, DOI 10.1155/2013/730829
   ROTONDO MF, 1993, J TRAUMA, V35, P375, DOI 10.1097/00005373-199309000-00008
   STONE HH, 1983, ANN SURG, V197, P532, DOI 10.1097/00000658-198305000-00005
   Tieu BH, 2008, J TRAUMA, V65, P865, DOI 10.1097/TA.0b013e31818481f1
   Verdam FJ, 2011, WORLD J SURG, V35, P2348, DOI 10.1007/s00268-011-1210-8
   Wang YF, 2018, INJURY, V49, P51, DOI 10.1016/j.injury.2017.11.033
   Weinberg JA, 2008, J TRAUMA, V65, P345, DOI 10.1097/TA.0b013e31817fa489
NR 31
TC 18
Z9 23
U1 0
U2 9
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD DEC
PY 2019
VL 43
IS 12
BP 3044
EP 3050
DI 10.1007/s00268-019-05166-w
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA JU7BI
UT WOS:000501827500013
PM 31506714
OA Bronze
DA 2026-07-24
ER

PT J
AU Tang, Y
   Liu, L
   Jie, RY
   Tang, YZ
   Zhao, XT
   Xu, MR
   Chen, MW
AF Tang, Ying
   Liu, Lei
   Jie, Ruyan
   Tang, Yizhong
   Zhao, Xiaotong
   Xu, Murong
   Chen, Mingwei
TI Negative pressure wound therapy promotes wound healing of diabetic foot
   ulcers by up-regulating PRDX2 in wound margin tissue
SO SCIENTIFIC REPORTS
LA English
DT Article
ID OXIDATIVE STRESS; SKIN
AB To understand the changes in the peroxiredoxin-2 (PRDX2) expression level in the wound margin tissue (T-PRDX2) of patients with diabetic foot ulcer (DFU) before and after negative pressure wound therapy (NPWT). Additionally, the study aimed to explore the association between PRDX2 expression and the treatment outcome of DFUs to provide a new theoretical basis for revealing the mechanism of NPWT promoting the healing of DFUs. Fifty-six type 2 diabetes patients with foot ulcers undergoing NPWT (the DFU group) and 28 patients with chronic lower limb skin ulcers with normal glucose tolerance undergoing NPWT (the skin ulcer control [SUC] group) were included in the study. T-PRDX2 was detected using Western blotting, and the superoxide dismutase (SOD) activity and the malondialdehyde (MDA) and glutathione (GSH) levels were detected using a biochemical method. In addition, in vitro experiments were conducted to determine the effect of PRDX2 expression on normal human dermal fibroblast (NHDF) proliferation, migration, and apoptosis. Before NPWT, the DFU group exhibited a significantly lower T-PRDX2 expression level compared with the SUC group. After one week of NPWT, the T-PRDX2 expression level, SOD activity, and GSH content in the wound margin tissues of the DFU and SUC groups significantly increased compared with the before NPWT levels. Conversely, the inflammatory indicators (white blood cell, neutrophil percentage, C-reactive protein, and procalcitonin) and MDA content were significantly lower than the before NPWT levels. The expression changes of T-PRDX2 before and after NPWT in the DFU and SUC groups were positively correlated with the 4-week wound healing rate. In vitro experiments demonstrated that PRDX2 could alleviate the oxidative stress in NHDFs, thereby promoting their proliferation and migration, while reducing cell apoptosis. NPWT promotes DFU healing by increasing T-PRDX2, and changes in the T-PRDX2 might be associated with the therapeutic effect of NPWT.
C1 [Tang, Ying; Liu, Lei; Jie, Ruyan; Zhao, Xiaotong; Xu, Murong; Chen, Mingwei] Anhui Med Univ, Affiliated Hosp 1, Dept Endocrinol, 218 Jixi Rd, Hefei, Anhui, Peoples R China.
   [Tang, Yizhong] Anhui Med Univ, Affiliated Hosp 1, Dept Burns, Hefei, Anhui, Peoples R China.
C3 Anhui Medical University; Anhui Medical University
RP Xu, MR; Chen, MW (通讯作者)，Anhui Med Univ, Affiliated Hosp 1, Dept Endocrinol, 218 Jixi Rd, Hefei, Anhui, Peoples R China.
EM crystally@foxmail.com; chmw1@163.com
RI ; Xu, Murong/HHS-2387-2022; CHEN, MINGWEI/KHT-6744-2024
OI Liu, Lei/0000-0002-4725-7941; 
FU We are grateful to the all patients for participating in the study. We
   thank the participants of this study including the doctors, nurses, and
   researchers from the Department of Endocrinology in the First Affiliated
   Hospital of Anhui Medical University.; Department of Endocrinology in
   the First Affiliated Hospital of Anhui Medical University
FX We are grateful to the all patients for participating in the study. We
   thank the participants of this study including the doctors, nurses, and
   researchers from the Department of Endocrinology in the First Affiliated
   Hospital of Anhui Medical University.
CR Akhter AS, 2021, INT WOUND J, V18, P158, DOI 10.1111/iwj.13507
   [Anonymous], 2019, CHIN J DIABETES MELL, V11, P92, DOI [10.1093/burnst/tkaa017, DOI 10.1093/BURNST/TKAA017, DOI 10.3760/CMA.J.ISSN.1674-5809.2019.02.004]
   Armstrong DG, 2018, NAT REV ENDOCRINOL, V14, P511, DOI 10.1038/s41574-018-0073-6
   Atkin Leanne, 2019, Br J Community Nurs, V24, pS26, DOI [10.12968/bjcn.2019.24.sup9.s26, 10.12968/bjcn.2019.24.Sup9.S26]
   Bellot GL, 2019, REDOX BIOL, V20, P307, DOI 10.1016/j.redox.2018.10.014
   Brinkmann C, 2011, EXP CLIN ENDOCR DIAB, V119, P559, DOI 10.1055/s-0031-1279712
   Burgess JL, 2021, MEDICINA-LITHUANIA, V57, DOI 10.3390/medicina57101072
   Chen LH, 2023, DIABETES OBES METAB, V25, P36, DOI 10.1111/dom.14840
   Chen L, 2021, ANN PALLIAT MED, V10, P10830, DOI 10.21037/apm-21-2476
   Chen X, 2020, THERANOSTICS, V10, P10290, DOI 10.7150/thno.46728
   Chen YQ, 2023, DIABETES, V72, P389, DOI 10.2337/db22-0553
   Feng AL, 2020, CLIN TRANSL ONCOL, V22, P1838, DOI 10.1007/s12094-020-02323-9
   Gao JR, 2021, J ADV NURS, V77, P3980, DOI 10.1111/jan.14876
   Han YH, 2020, IN VIVO, V34, P133, DOI 10.21873/invivo.11754
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Huang H, 2020, INT J MOL SCI, V21, DOI 10.3390/ijms21197413
   Jia ZG, 2021, MOL MED REP, V24, DOI 10.3892/mmr.2021.12474
   Jin X, 2017, SCI REP-UK, V7, DOI 10.1038/s41598-017-06718-7
   Kang SW, 2005, TRENDS MOL MED, V11, P571, DOI 10.1016/j.molmed.2005.10.006
   Kim MH, 2020, CELL BIOL INT, V44, P2086, DOI 10.1002/cbin.11417
   Kruse CR, 2016, J SURG RES, V206, P418, DOI 10.1016/j.jss.2016.08.060
   Lazzarini PA, 2023, DIABETOLOGIA, V66, P267, DOI 10.1007/s00125-022-05845-9
   Lee SC, 2003, J AM ACAD DERMATOL, V49, P487, DOI 10.1067/S0190-9622(03)01485-3
   Levey AS, 1999, ANN INTERN MED, V130, P461, DOI 10.7326/0003-4819-130-6-199903160-00002
   Li J, 2021, FRONT CARDIOVASC MED, V8, DOI 10.3389/fcvm.2021.624796
   Liu Y, 2022, FRONT IMMUNOL, V13, DOI 10.3389/fimmu.2022.918223
   Liu ZM, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD010318.pub3
   Luo P, 2022, ACTA PHARM SIN B, V12, P2300, DOI 10.1016/j.apsb.2021.12.007
   Martin P, 2015, BRIT J DERMATOL, V173, P370, DOI 10.1111/bjd.13954
   Mu SC, 2019, VASCULAR, V27, P381, DOI 10.1177/1708538119836360
   Park JG, 2011, CIRC RES, V109, P739, DOI 10.1161/CIRCRESAHA.111.245530
   Pastar I, 2021, EXP DERMATOL, V30, P1073, DOI 10.1111/exd.14325
   Patel S, 2019, BIOMED PHARMACOTHER, V112, DOI 10.1016/j.biopha.2019.108615
   Peng Y, 2021, CELL PROLIFERAT, V54, DOI 10.1111/cpr.12971
   Peskin AV, 2019, FREE RADICAL BIO MED, V145, P1, DOI 10.1016/j.freeradbiomed.2019.09.010
   Qiu XG, 2021, CLIN COSMET INV DERM, V14, P1745, DOI 10.2147/CCID.S334248
   Rosenberger DC, 2020, J NEURAL TRANSM, V127, P589, DOI 10.1007/s00702-020-02145-7
   van Netten JJ, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3268
   Vujcic S, 2022, MEDICINA-LITHUANIA, V58, DOI 10.3390/medicina58121866
   Wang GQ, 2018, BIOMED RES INT, V2018, DOI 10.1155/2018/9496183
   Xu GL, 2023, BIOCHEM BIOPH RES CO, V656, P139, DOI 10.1016/j.bbrc.2023.03.050
   Yazdanpanah L, 2018, DIABETES METAB SYND, V12, P519, DOI 10.1016/j.dsx.2018.03.018
   Yu Y, 2022, PHYTOMEDICINE, V98, DOI 10.1016/j.phymed.2022.153932
   Zhang PZ, 2017, ANN MED, V49, P106, DOI 10.1080/07853890.2016.1231932
   Zhang SR, 2020, PATHOL ONCOL RES, V26, P1869, DOI 10.1007/s12253-019-00783-1
   Zhang YQ, 2020, DIABETES CARE, V43, P964, DOI 10.2337/dc19-1614
   Zhao XT, 2023, INT WOUND J, V20, P413, DOI 10.1111/iwj.13890
   Zhao XT, 2023, INT WOUND J, V20, P467, DOI 10.1111/iwj.13895
   Zheng SW, 2021, J INTERV CARD ELECTR, V61, P245, DOI 10.1007/s10840-020-00805-y
   Zheng XR, 2020, AGING-US, V12, P16390, DOI 10.18632/aging.103690
NR 50
TC 11
Z9 15
U1 0
U2 22
PU NATURE PORTFOLIO
PI BERLIN
PA HEIDELBERGER PLATZ 3, BERLIN, 14197, GERMANY
SN 2045-2322
J9 SCI REP-UK
JI Sci Rep
PD SEP 27
PY 2023
VL 13
IS 1
AR 16192
DI 10.1038/s41598-023-42634-9
PG 15
WC Multidisciplinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Science & Technology - Other Topics
GA X7AX4
UT WOS:001099946000102
PM 37758743
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kadota, H
   Miyashita, K
   Fukushima, S
   Oryoji, C
   Hanada, M
   Yoshida, S
   Fujita, H
   Tachibana, Y
AF Kadota, Hideki
   Miyashita, Kayo
   Fukushima, Seita
   Oryoji, Chikafumi
   Hanada, Masuo
   Yoshida, Sei
   Fujita, Hayato
   Tachibana, Yukiko
TI Successful Management of a Severe Sacral Pressure Injury Penetrating to
   the Retroperitoneum
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE debridement; negative pressure wound therapy; pemphigus; pressure
   injury; retroperitoneal space
ID IRRIGATION; ABSCESSES
AB Introduction. Reports of retroperitoneal infection related to a sacral pressure injury (PI) are rare, and none of the reports described the direct spread of infection through the sacrum to the retroperitoneum. The authors present, to their knowledge, the first report of a severely infected PI that showed full-thickness sacral destruction and direct retroperitoneal penetration. Case Report. A 63-year-old female was referred for management of a stage 4 sacral PI complicated by a retroperitoneal abscess. The patient's comorbidities were diabetes mellitus and pemphigus foliaceus with steroid therapy-induced immunosuppression. Upon admission, the patient presented with a sacral PI producing copious purulent discharge that measured 5 cm x 3 cm. Magnetic resonance imaging revealed full-thickness sacral bone destruction and a massive retroperitoneal abscess, suggesting the sacral PI directly penetrated to the retroperitoneal space. Antibiotics were administered, and surgical debridement and sequestrectomy were performed. Negative pressure wound therapy (NPWT) with continuous saline irrigation was initiated. The patient's mesorectum was exposed within the retroperitoneal space. Therefore, a nonadhesive wound dressing was applied before placing the irrigation tube to avoid perforating the rectum. Because the patient had fragile skin secondary to long- standing pemphigus foliaceus and steroid treatment, a liquid skin protectant and hydrocolloid wound dressing were applied. The infection was successfully controlled with NPWT with saline irrigation. The patient experienced no rectal injury or skin rupture, and surgical closure was performed after 75 days. Although partial wound dehiscence occurred because of the poor condition of the skin, the resultant open wound was managed conservatively. The patient showed no retroperitoneal abscess recurrence 6 months later. Conclusions. A rare case of an intractable sacral PI complicated by retroperitoneal abscess was successfully managed in an immunocompromised patient. Notably, NPWT with saline irrigation was useful in controlling the patient's severe retroperitoneal infection.
C1 [Kadota, Hideki; Miyashita, Kayo; Fukushima, Seita; Oryoji, Chikafumi; Hanada, Masuo; Yoshida, Sei] Kyushu Univ Hosp, Dept Plast & Reconstruct Surg, Fukuoka, Japan.
   [Fujita, Hayato] Kyushu Univ, Grad Sch Med Sci, Dept Surg & Oncol, Fukuoka, Japan.
   [Tachibana, Yukiko] Kyushu Univ, Grad Sch Med Sci, Div Pressure Ulcer Prevent, Fukuoka, Japan.
C3 Kyushu University; Kyushu University; Kyushu University
RP Kadota, H (通讯作者)，3-1-1 Maidashi,Higashi Ku, Fukuoka 8128582, Japan.
EM kadohide@qent.med.kyushu-u.ac.jp
RI /AAU-7710-2020
CR Akhan O, 2020, DIAGN INTERV RADIOL, V26, P124, DOI 10.5152/dir.2019.19199
   Amagai M, 2014, J DERMATOL, V41, P471, DOI 10.1111/1346-8138.12486
   Braga IA, 2013, J HOSP INFECT, V83, P314, DOI 10.1016/j.jhin.2012.11.008
   Coelho RF, 2007, WORLD J SURG, V31, P431, DOI 10.1007/s00268-006-0162-x
   CREPPS JT, 1987, ANN SURG, V205, P276, DOI 10.1097/00000658-198703000-00010
   Edsberg LE, 2016, J WOUND OSTOMY CONT, V43, P585, DOI 10.1097/WON.0000000000000281
   Fujioka M, 2008, OSTOMY WOUND MANAG, V54, P44
   Fukui Kiyoko, 2018, Wounds, V30, pE5
   HARRIS LF, 1980, DIGEST DIS SCI, V25, P392, DOI 10.1007/BF01308066
   Kiyokawa K, 2007, PLAST RECONSTR SURG, V120, P1257, DOI 10.1097/01.prs.0000279332.27374.69
   Manjón GC, 2003, SCAND J UROL NEPHROL, V37, P139
   Schmidt E, 2019, LANCET, V394, P882, DOI 10.1016/S0140-6736(19)31778-7
   Song YP, 2019, INT WOUND J, V16, P1533, DOI 10.1111/iwj.13243
   Vinall Christopher, 2013, BMJ Case Rep, V2013, DOI 10.1136/bcr-2013-200479
   Yoon S, 2016, ARCH PLAST SURG-APS, V43, P586, DOI 10.5999/aps.2016.43.6.586
NR 15
TC 0
Z9 1
U1 0
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD MAR
PY 2021
VL 33
IS 3
BP E24
EP E27
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA SD0QQ
UT WOS:000651067900002
PM 33914698
DA 2026-07-24
ER

PT J
AU Fenske, J
   Kreiker, H
   Lampert, P
   Steffen, C
   Koerdt, S
   Nahles, S
   Kreutzer, K
   Heiland, M
   Rendenbach, C
   Neckel, N
AF Fenske, Jakob
   Kreiker, Henri
   Lampert, Philipp
   Steffen, Claudius
   Koerdt, Steffen
   Nahles, Susanne
   Kreutzer, Kilian
   Heiland, Max
   Rendenbach, Carsten
   Neckel, Norbert
TI Donor Site Morbidity in Fibula Free Flaps: A Technique-Dependent
   Comparative Analysis of Donor Site Wound Healing
SO MICROSURGERY
LA English
DT Article
DE donor site closure; fibula free flap; negative pressure wound therapy;
   primary closure; skin graft; two-stage closure
ID SKIN-GRAFTS; CLOSURE; MANAGEMENT; THERAPY
AB Background The fibula free flap (FFF) is a mainstay in maxillofacial reconstruction, yet donor site morbidity remains a significant clinical concern. Closure technique is a key factor influencing complication rates, but comparative data remain heterogeneous. This study provides a technique-dependent analysis of 60-day donor site wound healing in FFF with skin paddles and reports a two-stage closure approach.Methods A retrospective review of 211 patients undergoing FFF between 2017 and 2024 was conducted. Donor site complications within the first 60 postoperative days were assessed and stratified by closure technique: one-stage split-thickness skin grafting (STSG) with or without negative pressure wound therapy (NPWT), and a two-stage closure consisting of one-week NPWT followed by STSG. Multivariate logistic regression was applied to identify independent predictors for complications.Results Overall, 50.2% of patients experienced donor site complications, with wound healing disorders (31.8%) and (partial) skin necrosis (23.7%) most prevalent. Regarding wound closure, STSG coverage without NPWT was associated with the highest morbidity and a complication rate of 91.0%. Despite being limited in sample size, the two-stage closure, despite larger skin defects, showed complication rates comparable to one-stage closure with NPWT. Multivariate analysis identified STSG with NPWT (OR 0.1 [0.01; 0.4], p = 0.002) and two-stage closure (OR 0.1 [0.01; 0.5], p = 0.01) as protective factors for wound healing complications.Conclusion Donor site morbidity following FFF harvest with skin paddles is significantly impacted by closure technique. Wound management using one- or two-stage STSG with NPWT is preferred. Initial results of the two-stage closure indicate potentially beneficial outcomes for extensive defects and warrant further prospective validation.
C1 [Fenske, Jakob] Charite Univ Med Berlin, Dept Oral & Maxillofacial Surg, Berlin, Germany.
   Free Univ Berlin, Berlin, Germany.
   Humboldt Univ, Berlin, Germany.
C3 Free University of Berlin; Humboldt University of Berlin; Charite
   Universitatsmedizin Berlin; Free University of Berlin; Humboldt
   University of Berlin
RP Fenske, J (通讯作者)，Charite Univ Med Berlin, Dept Oral & Maxillofacial Surg, Berlin, Germany.
EM jakob.fenske@charite.de
RI ; Steffen, Claudius/AAS-6626-2021; Fenske, Jakob/LLM-2561-2024;
   Rendenbach, Carsten/E-8384-2013; Heiland, Max/IUM-8981-2023; Nahles,
   Susanne/C-1327-2019
OI Kreiker, Henri/0000-0003-1935-3546; Kreutzer,
   Kilian/0000-0003-0581-4137; Steffen, Claudius/0000-0003-4221-4878;
   Fenske, Jakob/0009-0000-3453-3903; Rendenbach,
   Carsten/0000-0002-9565-7640; Heiland, Max/0000-0002-4987-2913; Koerdt,
   Steffen/0000-0002-8679-8775; Nahles, Susanne/0000-0001-8522-0763
FU Projekt DEAL
FX Open Access funding enabled and organized by Projekt DEAL.
CR Akashi M, 2016, ORAL MAXILLOFAC SURG, V20, P233, DOI 10.1007/s10006-016-0556-3
   Archibald H, 2023, SEMIN PLAST SURG, V37, P26, DOI 10.1055/s-0042-1759795
   Attia S, 2020, CANCERS, V12, DOI 10.3390/cancers12082217
   Bach CA, 2016, HEAD NECK-J SCI SPEC, V38, P696, DOI 10.1002/hed.23952
   CEILLEY RI, 1983, J DERMATOL SURG ONC, V9, P288, DOI 10.1111/j.1524-4725.1983.tb00804.x
   Denys E, 2024, J ORAL MAXIL SURG, V82, P728, DOI 10.1016/j.joms.2024.03.003
   ElHawary H, 2023, PRS-GLOB OPEN, V11, DOI 10.1097/GOX.0000000000005172
   Feng KM, 2020, MICROSURG, V40, P741, DOI 10.1002/micr.30621
   Gefen A, 2024, INT WOUND J, V21, DOI [10.1111/iwj.70098, 10.1111/iwj.70098]
   Ho MWS, 2013, JAMA OTOLARYNGOL, V139, P1048, DOI 10.1001/jamaoto.2013.4544
   Kaleem A, 2021, MICROSURG, V41, P233, DOI 10.1002/micr.30692
   Kim PD, 2008, ARCH OTOLARYNGOL, V134, P1324, DOI 10.1001/archotol.134.12.1324
   Lee ZH, 2025, J PLAST RECONSTR AES, V100, P240, DOI 10.1016/j.bjps.2024.11.034
   Lewis RH Jr, 2020, J TRAUMA ACUTE CARE, V89, P377, DOI 10.1097/TA.0000000000002759
   Ling XF, 2012, PLAST RECONSTR SURG, V129, P657, DOI 10.1097/PRS.0b013e3182402d9a
   Momoh AO, 2011, PLAST RECONSTR SURG, V128, P714, DOI 10.1097/PRS.0b013e318221dc2a
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Rendenbach C, 2018, MICROSURG, V38, P395, DOI 10.1002/micr.30205
   Rendenbach C, 2016, J CRANIO MAXILL SURG, V44, P155, DOI 10.1016/j.jcms.2015.10.027
   Shimbo K, 2022, MICROSURG, V42, P192, DOI 10.1002/micr.30781
   Sieg P, 2010, BRIT J ORAL MAX SURG, V48, P267, DOI 10.1016/j.bjoms.2009.07.019
   Squadrelli-Saraceno M, 2010, ACTA OTORHINOLARYNGO, V30, P40
   Wang YY, 2016, J ORAL MAXIL SURG, V74, P200, DOI 10.1016/j.joms.2015.08.015
   Xiang FP, 2024, INDIAN J SURG, V86, P1114, DOI 10.1007/s12262-024-04053-6
   Zimmermann C E, 2001, Clin Oral Investig, V5, P214
NR 25
TC 0
Z9 1
U1 0
U2 0
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0738-1085
EI 1098-2752
J9 MICROSURG
JI Microsurgery
PD NOV 5
PY 2025
VL 45
IS 8
AR e70139
DI 10.1002/micr.70139
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 9JN0O
UT WOS:001607854500001
PM 41190704
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Wei, P
   Wu, LJ
   Xie, HT
   Chen, ZH
   Tan, RW
   Xu, ZR
AF Wei, Pei
   Wu, Lijiao
   Xie, Hongteng
   Chen, Zhaohong
   Tan, Rongwei
   Xu, Zhaorong
TI Application of a meshed artificial dermal scaffold and negative-pressure
   wound therapy in the treatment of full-thickness skin defects: a
   prospective in vivo study
SO BIOMATERIALS SCIENCE
LA English
DT Article
ID RECONSTRUCTION; INTEGRA; MECHANISM
AB Artificial dermal scaffolds (ADSs) have great value in repairing deep skin defects. However, problems such as unsatisfactory angiogenesis and local dropsy or empyema often occur, resulting in delayed or even failed wound healing. Negative pressure wound therapy (NPWT) is an effective therapy to promote wound healing or shorten wound bed preparation time. Studies on whether it can improve the effects of ADSs have never been interrupted, and no consensus has been reached. In this study, an improved ADS was prepared by mesh technology, physicochemical experiments were conducted, cell adhesion and proliferation were assessed with the meshed ADS, and in vivo experiments were conducted to investigate the effects of meshed ADS or ADS combined with NPWT in repairing full-thickness skin defects. The results showed that the meshed ADS showed through-layer channels arranged in parallel longitudinal and transverse intersections. The cell experiments confirmed the good cytocompatibility. The in vivo experiments showed that there were no differences in the take rate or contraction of grafted skin among all experiment groups. The meshed ADS exhibited good histocompatibility, and there were no differences in tissue inflammation, dermal angiogenesis, or degradation among all groups. In addition, necrosis, dropsy, or empyema of the dermal scaffold were found in all experiment groups except for the meshed ADS + NPWT group, which showed better wound repair results, including fewer scaffold-related complications and satisfactory skin graft survival and wound contraction. In conclusion, this novel meshed ADS, which has a regular through-layer mesh structure and possesses stable physicochemical properties and good biocompatibility, combined with NPWT can ensure adequate subdermal drainage and reduce the risk of scaffold-related complications, thereby improving the quality and efficiency of wound repair, promoting a broader application of biomaterials, and helping physicians and readers implement more effective wound management.
C1 [Wei, Pei; Xie, Hongteng; Chen, Zhaohong; Xu, Zhaorong] Fujian Med Univ, Burn & Wound Repair Dept, Union Hosp, Fuzhou 350001, Peoples R China.
   [Wei, Pei; Xie, Hongteng; Chen, Zhaohong; Xu, Zhaorong] Fujian Med Univ, Fujian Burn Inst, Union Hosp, Fuzhou 350001, Peoples R China.
   [Wei, Pei; Xie, Hongteng; Chen, Zhaohong; Xu, Zhaorong] Fujian Med Univ, Fujian Prov Key Lab Burn & Trauma, Union Hosp, Fuzhou 350001, Peoples R China.
   [Wu, Lijiao] Fujian Prov Hosp, Dept Orthoped Surg, South Branch, Fuzhou 350001, Peoples R China.
   [Wu, Lijiao] Fujian Med Univ, Shengli Clin Med Coll, Fuzhou 350001, Peoples R China.
   [Tan, Rongwei] Shenzhen Lando Biomat Co Ltd, GuangDong Engn Technol Res Ctr Implantable Med Pol, Shenzhen 518107, Peoples R China.
C3 Fujian Medical University; Fujian Medical University; Fujian Medical
   University; Fujian Provincial Hospital; Fujian Medical University
RP Xu, ZR (通讯作者)，Fujian Med Univ, Burn & Wound Repair Dept, Union Hosp, Fuzhou 350001, Peoples R China.; Xu, ZR (通讯作者)，Fujian Med Univ, Fujian Burn Inst, Union Hosp, Fuzhou 350001, Peoples R China.; Xu, ZR (通讯作者)，Fujian Med Univ, Fujian Prov Key Lab Burn & Trauma, Union Hosp, Fuzhou 350001, Peoples R China.
EM 234828306@qq.com
FU National Natural Science Foundation of China [[2021]76]; High-level
   Hospital and Clinical Specialty Discipline Construction Programme for
   Fujian Medical Development, China; Fujian Provincial Key Laboratory of
   Burn and Trauma [82002034]; National Natural Science Foundation of China
   [2021Y9068]; Joint Funds for the Innovation of Science and Technology,
   Fujian Province, China
FX This work was supported by the High-level Hospital and Clinical
   Specialty Discipline Construction Programme for Fujian Medical
   Development, China ([2021]76), the Fujian Provincial Key Laboratory of
   Burn and Trauma, the National Natural Science Foundation of China
   (82002034), and the Joint Funds for the Innovation of Science and
   Technology, Fujian Province, China (2021Y9068).
CR Almeida IR, 2023, ANN SURG, V277, P198, DOI 10.1097/SLA.0000000000005371
   Angelis B. D., 2018, INT WOUND J, V15, P1
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Baldwin C, 2009, ANN PLAS SURG, V62, P92, DOI 10.1097/SAP.0b013e31817762fd
   Bargues L, 2009, ANN CHIR PLAST ESTH, V54, P533, DOI 10.1016/j.anplas.2008.10.013
   berg S., 2017, SURG INNOV, V24, P289
   Chen J, 2023, POLYMERS-BASEL, V15, DOI 10.3390/polym15092015
   Chua AWC, 2016, BURNS TRAUMA, V4, DOI 10.1186/s41038-016-0027-y
   Corrêa FB, 2022, WOUND REPAIR REGEN, V30, P222, DOI 10.1111/wrr.13002
   De Angelis B, 2019, J CLIN MED, V8, DOI 10.3390/jcm8040525
   Diehm YF, 2021, J PLAST RECONSTR AES, V74, P357, DOI 10.1016/j.bjps.2020.08.041
   Dill V, 2020, INT WOUND J, V17, P618, DOI 10.1111/iwj.13314
   Dongmei Ge B., 2018, ADV SKIN WOUND CARE, V3, P421
   Eisenhardt SU, 2012, J PLAST RECONSTR AES, V65, P640, DOI 10.1016/j.bjps.2011.11.037
   Francesco F. D., 2020, J INT MED RES, V48, P1
   Frueh FS, 2017, CRIT REV BIOTECHNOL, V37, P613, DOI 10.1080/07388551.2016.1209157
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Guo R, 2011, BIOMATERIALS, V32, P1019, DOI 10.1016/j.biomaterials.2010.08.087
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Hudgins PA, 2002, EUR J RADIOL, V44, P130, DOI 10.1016/S0720-048X(02)00067-0
   Jeschke MG, 2004, PLAST RECONSTR SURG, V113, P525, DOI 10.1097/01.PRS.0000100813.39746.5A
   Koyuncuoglu CZ, 2014, J ORAL IMPLANTOL, V40, P715, DOI 10.1563/AAID-JOI-D-12-00072
   Laschke MW, 2016, BIOTECHNOL ADV, V34, P112, DOI 10.1016/j.biotechadv.2015.12.004
   Leffler M, 2010, J PLAST RECONSTR AES, V63, pE32, DOI 10.1016/j.bjps.2009.05.022
   Lohana P, 2014, Ann Burns Fire Disasters, V27, P17
   Lotan AM, 2019, PLAST RECONSTR SURG, V144, P1045, DOI 10.1097/PRS.0000000000006116
   Lucich EA, 2018, REGEN MED, V13, P443, DOI 10.2217/rme-2017-0047
   Maguire CR, 2017, PEDIATR SURG INT, V33, P823, DOI 10.1007/s00383-017-4095-2
   Mandrycky C, 2016, BIOTECHNOL ADV, V34, P422, DOI 10.1016/j.biotechadv.2015.12.011
   Mir A, 2023, BIOENGINEERING-BASEL, V10, DOI 10.3390/bioengineering10050606
   Moiemen NS, 2010, BURNS, V36, P764, DOI 10.1016/j.burns.2010.04.011
   Moiemen NS, 2006, PLAST RECONSTR SURG, V117, p160S, DOI 10.1097/01.prs.0000222609.40461.68
   Pappalardo Vincenzo, 2019, Surg Technol Int, V34, P56
   Pollard RLE, 2008, J PLAST RECONSTR AES, V61, P319, DOI 10.1016/j.bjps.2007.10.029
   POPE ER, 1990, VET CLIN N AM-SMALL, V20, P177, DOI 10.1016/S0195-5616(90)50009-1
   Scheflan M, 2018, PLAST RECONSTR SURG, V141, p1E, DOI 10.1097/PRS.0000000000003982
   Shao H W, 2017, Zhonghua Shao Shang Za Zhi, V33, P523, DOI 10.3760/cma.j.issn.1009-2587.2017.08.019
   Simman Richard, 2011, J Am Col Certif Wound Spec, V3, P55, DOI 10.1016/j.jcws.2012.03.001
   Stiefel D, 2009, J PEDIATR SURG, V44, P575, DOI 10.1016/j.jpedsurg.2008.07.006
   Weisel A, 2022, J TISSUE ENG REGEN M, V16, P1173, DOI 10.1002/term.3356
   Xu ZR, 2019, MAT SCI ENG C-MATER, V105, DOI 10.1016/j.msec.2019.110063
   Zhang LP, 2020, BIOMED RES INT, V2020, DOI 10.1155/2020/8824737
   Zingaretti N, 2018, AESTHET PLAST SURG, V42, P1704, DOI 10.1007/s00266-018-1090-5
NR 43
TC 4
Z9 4
U1 1
U2 3
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
   ENGLAND
SN 2047-4830
EI 2047-4849
J9 BIOMATER SCI-UK
JI Biomater. Sci.
PD MAR 26
PY 2024
VL 12
IS 7
BP 1914
EP 1923
DI 10.1039/d3bm01675g
EA MAR 2024
PG 10
WC Materials Science, Biomaterials
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Materials Science
GA MA1J3
UT WOS:001179298700001
PM 38436071
OA hybrid
DA 2026-07-24
ER

PT J
AU Zhang, H
   Zhou, M
   Wang, Y
   Zhang, D
   Qi, BW
   Yu, AX
AF Zhang, Hao
   Zhou, Min
   Wang, Yu
   Zhang, Dong
   Qi, Baiwen
   Yu, Aixi
TI Role of Autologous Fat Transplantation Combined with Negative-Pressure
   Wound Therapy in Treating Rat Diabetic Wounds
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID STEM-CELLS; METAANALYSIS; MACROPHAGES; PHENOTYPE
AB Background:Negative-pressure wound therapy (NPWT) and autologous fat transplantation (AFT) are two clinical modalities for plastic and reconstructive surgery. At present, there are few reports on the combination of these two methods in treating diabetic wounds. This study aimed to explore the effect of this combined therapy on diabetic wound healing.Methods:Full-thickness dorsal cutaneous wounds in rats with streptozotocin-induced diabetes were treated with either NPWT, AFT, or combined therapy. Rats covered with commercial dressings served as the control group. Macroscopic healing kinetics were examined. The levels of inflammation-related factors, such as interleukin-1 & beta; (IL-1 & beta;), interleukin-6 (IL-6), monocyte chemoattractant protein-1, arginase-1, and inducible nitric oxide synthase (iNOS) and angiogenesis-related factors such as vascular endothelial growth factor, were measured in the wound tissues on days 3, 7, and 14; immunohistochemical staining for arginase-1, iNOS, and CD31 was performed on days 3, 7, and 14. The length of reepithelialization was investigated on day 14.Results:The combined therapy promoted faster wound healing than the other treatments. The expression levels of the proinflammatory factors IL-1 & beta;, IL-6, monocyte chemoattractant protein-1 (MCP-1), and iNOS were reduced, and arginase-1 expression was increased compared with those in the other groups. The expression levels of vascular endothelial growth factor and CD31 in the NPWT-combined-with-AFT group were significantly higher than those in the other groups. Reepithelialization was faster in the NPWT-combined-with-AFT group (by day 14) than in the other groups.Conclusion:Combining NPWT and AFT can enhance diabetic wound healing by improving wound inflammation and increasing wound vascularization.Clinical Relevance Statement:The authors designed a randomized controlled trial of diabetic rats to confirm that NPWT can enhance the vascularization and improve inflammation of the diabetic wound after the autologous fat transplantation treatment. This article may provide a new idea for treating diabetic wounds.
C1 [Zhang, Hao; Zhou, Min; Wang, Yu; Zhang, Dong; Qi, Baiwen; Yu, Aixi] Wuhan Univ, Zhongnan Hosp, Dept Orthoped Trauma & Microsurg, Wuhan, Peoples R China.
   [Qi, Baiwen; Yu, Aixi] Wuhan Univ, Zhongnan Hosp, 169 Donghu Rd, Wuhan 430072, Hubei, Peoples R China.
C3 Wuhan University; Wuhan University
RP Qi, BW; Yu, AX (通讯作者)，Wuhan Univ, Zhongnan Hosp, 169 Donghu Rd, Wuhan 430072, Hubei, Peoples R China.
EM wb002162@whu.edu.cn; yuaixi@whu.edu.cn
FU Zhongnan Hospital of Wuhan University and Joint Fund Project of Health
   Commission of Hubei Province [WJ2019H067]; Natural Science Foundation of
   Hubei Province [2020CFB662]; Health Commission of Hubei Province Medical
   Leading Talent Project [LJ20200405]
FX This study was supported by Zhongnan Hospital of Wuhan University and
   Joint Fund Project of Health Commission of Hubei Province (grant
   WJ2019H067), the Natural Science Foundation of Hubei Province (grant
   2020CFB662), and the Health Commission of Hubei Province Medical Leading
   Talent Project (grant LJ20200405).
CR Bassi EJ, 2012, DIABETES, V61, P2534, DOI 10.2337/db11-0844
   Borst SE, 2004, ENDOCRINE, V23, P177, DOI 10.1385/ENDO:23:2-3:177
   Borys S, 2019, EUR J CLIN INVEST, V49, DOI 10.1111/eci.13067
   Bravo B, 2017, J CELL PHYSIOL, V232, P2158, DOI 10.1002/jcp.25712
   Chen B, 2017, PLAST RECONSTR SURG, V139, P105, DOI 10.1097/PRS.0000000000002909
   Choi JR, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0115034
   Franck CL, 2019, STEM CELLS INT, V2019, DOI 10.1155/2019/2340725
   Guo JM, 2018, AM J PHYSIOL-CELL PH, V315, pC885, DOI 10.1152/ajpcell.00120.2018
   Hanson SE, 2021, AESTHET SURG J, V41, pS69, DOI 10.1093/asj/sjab130
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Kao HK, 2015, BRIT J SURG, V102, P998, DOI 10.1002/bjs.9826
   Khanna S, 2010, PLOS ONE, V5, DOI 10.1371/journal.pone.0009539
   Kruger MJ, 2018, J MOL ENDOCRINOL, V61, P173, DOI 10.1530/JME-18-0078
   Latham KA, 2005, J IMMUNOL, V174, P3978, DOI 10.4049/jimmunol.174.7.3978
   Lee SW, 2012, EMBO MOL MED, V4, P924, DOI 10.1002/emmm.201101107
   Li G, 2013, CELL PROLIFERAT, V46, P586, DOI 10.1111/cpr.12053
   Lindley LE, 2016, PLAST RECONSTR SURG, V138, p18S, DOI 10.1097/PRS.0000000000002682
   Lobmann R, 2005, DIABETES CARE, V28, P461, DOI 10.2337/diacare.28.2.461
   Malone-Povolny MJ, 2019, ADV HEALTHC MATER, V8, DOI 10.1002/adhm.201801210
   Marsboom G, 2018, PHYSIOLOGY, V33, P328, DOI 10.1152/physiol.00018.2018
   Mazini L, 2019, INT J MOL SCI, V20, DOI 10.3390/ijms20102523
   Meloni M, 2015, WORLD J ORTHOP, V6, P387, DOI 10.5312/wjo.v6.i4.387
   Mills CD, 2000, J IMMUNOL, V164, P6166, DOI 10.4049/jimmunol.164.12.6166
   Mirza RE, 2013, DIABETES, V62, P2579, DOI 10.2337/db12-1450
   Rennert RC, 2014, STEM CELL RES THER, V5, DOI 10.1186/scrt468
   Rodrigues M, 2019, PHYSIOL REV, V99, P665, DOI 10.1152/physrev.00067.2017
   Ruane EJ, 2019, PLAST RECONSTR SURG, V144, p463E, DOI 10.1097/PRS.0000000000005956
   Rys P, 2020, ENDOCRINE, V68, P44, DOI 10.1007/s12020-019-02164-9
   Safwani WKZW, 2017, CRYOBIOLOGY, V75, P91, DOI 10.1016/j.cryobiol.2017.01.006
   Shim YH, 2017, AESTHET PLAST SURG, V41, P815, DOI 10.1007/s00266-017-0793-3
   Stubbs SL, 2012, STEM CELLS DEV, V21, P1887, DOI 10.1089/scd.2011.0289
   Thangarajah H, 2009, STEM CELLS, V27, P266, DOI 10.1634/stemcells.2008-0276
   Timmermans FW, 2021, BJS-BRIT J SURG, V108, P925, DOI 10.1093/bjs/znab204
   Wang T, 2017, DIABETES-METAB RES, V33, DOI 10.1002/dmrr.2871
   Wang T, 2019, DIABETES RES CLIN PR, V150, P81, DOI 10.1016/j.diabres.2019.02.024
   Zhao H, 2018, DIABETES, V67, P235, DOI 10.2337/db17-0356
   Zheng BY, 2021, J WOUND CARE, V30, pS38, DOI 10.12968/jowc.2021.30.Sup4.S38
NR 37
TC 5
Z9 5
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD SEP
PY 2023
VL 152
IS 3
BP 561
EP 570
DI 10.1097/PRS.0000000000010226
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA Q6XM5
UT WOS:001058934500038
PM 36727776
DA 2026-07-24
ER

PT J
AU Lumpkins, A
   Stanton, T
AF Lumpkins, April
   Stanton, Tamara
TI Benefits of a Patient-centered Remote Therapy Monitoring Program
   Focusing on Increased Adherence to Wound Therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
DE remote therapy monitoring; negative pressure wound therapy; RTM; NPWT;
   patient adherence; patient compliance
AB Introduction. Patient nonadherence to wound care protocols may impact the efficacy of modalities, such as negative pressure wound therapy (NPWT). Recently, a remote therapy monitoring (RTM) system has been devised for use with NPWT for home care patients. Objective. Three home care patients receiving NPWT are presented to examine the relationship between patients using the RTM system and Virtual Therapy Specialists (VTS). Materials and Methods. Consent was secured from patients with either multiple comorbidities and/or wounds of varying complexity. Wounds were assessed as per their initial presentation, and all patients were discharged home with an RTM-equipped NPWT system to apply continuous subatmospheric pressure to their wound. Dressings were changed every 2 to 3 days. Results. All 3 patients were women (age range, 53-72 years), who presented with the following wound types: recalcitrant abdominal wound, acute wound following ventral hernia repair, and dehisced wound following a hysterectomy. Patient 1 was treated with RTM-equipped NPWT for a duration of 88 days (6 nonadherent vs. 82 adherent days) and was adherent to the therapy 93.2% of the time. Patient 2 was treated with RTM-equipped NPWT for a duration of 57 days (8 nonadherent vs. 49 adherent days) and was adherent to the therapy 86.0% of the time. Patient 3 was treated with RTM-equipped NPWT for a duration of 16 days (2 nonadherent vs. 14 adherent days) and was adherent to the therapy 87.5% of the time. Each patient presented with a barrier to therapy adherence (eg, lack of access to residential clinical support, technical issues, or work demands) that was managed by VTS interactions. Conclusions. In these 3 cases, RTM-equipped NPWT and the patient-centric exchanges with the VTS through adherence calls helped promote consistent usage of RTM-equipped NPWT to address the patients' therapeutic needs and increase therapy adherence.
C1 [Lumpkins, April; Stanton, Tamara] KCI, San Antonio, TX USA.
RP Lumpkins, A (通讯作者)，12930 West Interstate 10, San Antonio, TX 78249 USA.
EM April.Lumpkins@Acelity.com
FU KCI, an Acelity Company
FX The authors are employees of KCI, an Acelity Company (San Antonio, TX).
   Financial support for this research was provided by KCI, an Acelity
   Company. Willie M. Heard III, PhD (KCI, an Acelity Company), provided
   medical writing support. These data were presented at the Symposium on
   Advanced Wound Care Fall 2018 in Las Vegas, NV.
CR Griffin L, 2019, WOUNDS, V31, pE9
   Griffin L, 2018, WOUNDS, V30, pE81
   Iuga AO, 2014, RISK MANAG HEALTHC P, V7, P35, DOI 10.2147/RMHP.S19801
   Reach G, 2016, PATIENT PREFER ADHER, V10, P459, DOI 10.2147/PPA.S99627
   Sabate E :., 2003, ADHERENCE LONG TERM
NR 5
TC 1
Z9 2
U1 0
U2 4
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD AUG
PY 2019
VL 31
IS 8
BP E49
EP E53
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA IV5AI
UT WOS:000484283200002
PM 31483754
DA 2026-07-24
ER

PT J
AU Tahir, S
   Malone, M
   Hu, HH
   Deva, A
   Vickery, K
AF Tahir, Shamaila
   Malone, Matthew
   Hu, Honghua
   Deva, Anand
   Vickery, Karen
TI The Effect of Negative Pressure Wound Therapy with and without
   Instillation on Mature Biofilms In Vitro
SO MATERIALS
LA English
DT Article
DE biofilm; chronic wounds; instillation therapy; in vitro
ID BACTERIAL LOAD; INFECTIONS; BIOBURDEN
AB Background: To investigate the effect of negative pressure wound therapy (NPWT) with and without instillation (NPWTi) on in vitro mature biofilm. Methods: Mature biofilms of Pseudomonas aeruginosa and Staphylococcus aureus were grown under shear (130 rpm) on polycarbonate coupons in a CDC biofilm reactor for 3 days. Coupons containing biofilms were placed in a sterile petri dish and sealed using NPWT or NPWTi. Coupons were exposed to treatment for 24 h with NPWT alone or with instillation of: Povidone iodine solution (PVP-I) (10% w/v equivalent to 1% w/v available iodine, BETADINE (R), Mundipharma, Singapore), surfactant based antimicrobial solution with polyhexamethylene biguanide (SBPHMB) (Prontosan (R), B Braun Medical, Melsungen, Germany), Gentamicin 1 mu g/mL (GM) (G1264 Sigma-Aldrich Pty Ltd., Castle Hill, Australia) Rifampicin 24 mu g/mL (RF) (R3501 Sigma-Aldrich Pty Ltd., Castle Hill, Australia) and NaCl 0.9% (Baxter, Deerfield, IL, USA). Bacterial cell viability and biofilm architecture pre-and post-treatment were assessed using colony forming units (cfu), Live/ Dead viability staining, confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM). Results: Significant reductions were obtained in S. aureus biofilm thickness (65%) and mass (47%) when treated with NPWTi as compared to NPWT only. NPWTi with instillation of SBPHMB, PVP-I and RF achieved between 2 and 8 log(10) reductions against S. aureus biofilm (p < 0.05-0.001). Conversely, PVP-I and SBMO achieved a 3.5 log(10) reduction against P. aeruginosa (p < 0.05). Conclusions: NPWT alters biofilm architecture by reducing biofilm thickness and mass, but this does not affect bacterial cell viability. NPWT with instillation of certain antimicrobials solutions may provide a further synergistic effect in reducing the number of viable biofilm microorganisms. Our in vitro model may be used for screening the effectiveness of antimicrobials used under instillation prior to animal or human studies.
C1 [Tahir, Shamaila; Hu, Honghua; Deva, Anand; Vickery, Karen] Macquarie Univ, Surg Infect Res Grp, Fac Med & Hlth Sci, Sydney, NSW 2109, Australia.
   [Malone, Matthew] Univ Western Sydney, Sch Med, Infect Dis & Microbiol, Sydney, NSW 2751, Australia.
   [Malone, Matthew] Ingham Inst Appl Med Res, Liverpool Diabet Collaborat Res Unit, Sydney, NSW 2170, Australia.
   [Malone, Matthew] Liverpool Hosp, High Risk Foot Serv, South West Sydney LHD, Sydney, NSW 2170, Australia.
C3 Macquarie University; Western Sydney University; Ingham Institute for
   Applied Medical Research; Liverpool Hospital
RP Tahir, S (通讯作者)，Macquarie Univ, Surg Infect Res Grp, Fac Med & Hlth Sci, Sydney, NSW 2109, Australia.
EM shamaila.tahir@students.mq.edu.au; matthew.malone@westernsydney.edu.au;
   helen.hu@mq.edu.au; anand.deva@mq.edu.au; karen.vickery@mq.edu.au
RI ; Hu, Honghua/AAG-2202-2021
OI Vickery, Karen/0000-0003-0998-1370; Hu, Honghua/0000-0002-3749-4089;
   Deva, Anand/0000-0002-0314-7177
FU Australian postgraduate award (APA); Macquarie University Vice
   Chancellor Innovation Fellowship
FX We would like to thank KCI Medical Pty. Ltd. for providing the V.A.C.(R)
   machines and consumables. Shamaila Tahir was in receipt of Australian
   postgraduate award (APA). A/Professor Vickery was in receipt of a
   Macquarie University Vice Chancellor Innovation Fellowship.
CR Andros G, 2006, OSTOMY WOUND MANAG, P1
   Armstrong DG, 2017, NEW ENGL J MED, V376, P2367, DOI 10.1056/NEJMra1615439
   Burmolle M, 2010, FEMS IMMUNOL MED MIC, V59, P324, DOI 10.1111/j.1574-695X.2010.00714.x
   Goeres DM, 2005, MICROBIOL-SGM, V151, P757, DOI 10.1099/mic.0.27709-0
   Goss S G, 2012, J Am Coll Clin Wound Spec, V4, P74, DOI 10.1016/j.jccw.2014.02.001
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Hadi R, 2010, J HOSP INFECT, V74, P160, DOI 10.1016/j.jhin.2009.10.023
   Lipsky BA, 2016, DIABETES-METAB RES, V32, P45, DOI 10.1002/dmrr.2699
   Malone M, 2017, EBIOMEDICINE, V21, P142, DOI 10.1016/j.ebiom.2017.06.026
   Malone M, 2017, EXPERT REV ANTI-INFE, V15, P147, DOI 10.1080/14787210.2017.1262257
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Ngo QD, 2012, WOUND REPAIR REGEN, V20, P83, DOI 10.1111/j.1524-475X.2011.00747.x
   Phillips PL, 2013, INT WOUND J, V10, P48, DOI 10.1111/iwj.12180
   Schwartz JA, 2014, J WOUND CARE, V23, pS4, DOI 10.12968/jowc.2014.23.Sup9.S4
   Sen CK, 2009, WOUND REPAIR REGEN, V17, P1, DOI 10.1111/j.1524-475X.2008.00436.x
   Singh D, 2017, WOUNDS, V29, P175
   Valente PMDS, 2016, INT WOUND J, V13, P130, DOI 10.1111/iwj.12248
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Yusuf E, 2013, WOUND REPAIR REGEN, V21, P677, DOI 10.1111/wrr.12088
NR 19
TC 26
Z9 37
U1 0
U2 10
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
EI 1996-1944
J9 MATERIALS
JI Materials
PD MAY
PY 2018
VL 11
IS 5
AR 811
DI 10.3390/ma11050811
PG 11
WC Chemistry, Physical; Materials Science, Multidisciplinary; Metallurgy &
   Metallurgical Engineering; Physics, Applied; Physics, Condensed Matter
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Chemistry; Materials Science; Metallurgy & Metallurgical Engineering;
   Physics
GA GI7VY
UT WOS:000434711700161
PM 29772696
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Horch, RE
AF Horch, Raymund E.
TI INCISIONAL NEGATIVE PRESSURE WOUND THERAPY FOR HIGH-RISK WOUNDS
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE surgical incision management; negative pressure wound therapy; closed
   incision; topical negative pressure therapy; skin circulation; Prevena
   Therapy
ID SURGICAL INCISION; MANAGEMENT-SYSTEM; WEIGHT-LOSS; SURGERY;
   ABDOMINOPLASTY; COMPLICATIONS; PERFUSION; CLOSURES; VACUUM
AB With an ageing population and a growing number of people with obesity and/or undergoing advanced cancer therapies, there is an increasing risk of surgical site complications including surgical site infections (SSIs). Postoperative shifting of large mobilised tissue flaps, such as in abdominoplasties, remains a dreaded complication, particularly following massive weight loss. Besides negative implications for the patient, surgical site complications result in an economic burden due to prolonged and repeated wound treatments. Preventative tools to reduce SSIs are needed. In selected patients at high risk of SSI and/or wound breakdown, use of incisional NPWT has been shown to actively manage clean, closed surgical incisions. This article contains a review of scientific and clinical research relevant to incisional NPWT use over surgical incisions, with particular emphasis on the common problem of wound breakdown and SSI following body-contouring surgery in post-bariatric patients. Although there are a growing number of studies describing use of incisional NPWT in a variety of applications, including vascular, cardiac and orthopaedic, a literature search revealed few studies regarding incisional NPWT use post body-contouring surgery. In a clinical study of seroma formation, less seroma and haematoma formation was reported in post-bariatric patients who received incisional NPWT, versus the control, following body-contouring surgery. In another study of widely applied external NPWT wound dressings over the ventral and lateral trunk following post-bariatric abdominal dermolipectomy, results showed a significant reduction in exudate formation, earlier drain removal, and decreased length of hospitalisation, compared with conventional treatment. Additional controlled studies are needed to validate the clinical impact of incisional NPWT following body-contouring surgery, and to determine proper recommendations for its use.
C1 Univ Erlangen Nurnberg, Univ Hosp Erlangen, Lab Tissue Engn & Regenerat Med, Dept Plast & Hand Surg & Director, Erlangen, Germany.
C3 University of Erlangen Nuremberg
RP Horch, RE (通讯作者)，Univ Erlangen Nurnberg, Univ Hosp Erlangen, Lab Tissue Engn & Regenerat Med, Dept Plast & Hand Surg & Director, Erlangen, Germany.
EM Raymund.Horch@uk-erlangen.de
RI Horch, Raymund/H-8128-2019
FU KCI, an Acelity company
FX REH served as a scientific advisor to KCI, an Acelity company, and
   presented as a faculty member during the 2014 International Surgical
   Wound Forum (ISWF), an annual educational event sponsored by KCI, an
   Acelity company. This article is part of a KCI-funded educational
   supplement based on 2014 ISWF faculty presentations. Acelity provided
   editorial assistance.
CR Altintas B, 2015, INT WOUND J, V12, P662, DOI 10.1111/iwj.12198
   Atkins BZ, 2011, INT WOUND J, V8, P56, DOI 10.1111/j.1742-481X.2010.00743.x
   Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Baharestani M, 2008, ADV SKIN WOUND CARE, V21, P1
   Bercial ME, 2012, AESTHET PLAST SURG, V36, P370, DOI 10.1007/s00266-011-9807-8
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Condé-Green A, 2013, ANN PLAS SURG, V71, P394, DOI 10.1097/SAP.0b013e31824c9073
   Constantine RS, 2014, AESTHET SURG J, V34, P578, DOI 10.1177/1090820X14528208
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   di Summa PG, 2013, ANN PLAS SURG, V71, P461, DOI 10.1097/SAP.0b013e3182503ad9
   Dohmen PM, 2014, EXPERT REV MED DEVIC, V11, P395, DOI 10.1586/17434440.2014.911081
   Dragu A, 2012, OBESITY FACTS, V5, P651, DOI 10.1159/000343662
   Dragu A, 2011, OBES SURG, V21, P1781, DOI 10.1007/s11695-010-0328-3
   Dragu A, 2010, CAN J SURG, V53, P137
   Dragu A, 2009, OBES SURG, V19, P1599, DOI 10.1007/s11695-008-9559-y
   Grauhan O, 2014, INT WOUND J, V11, P6, DOI 10.1111/iwj.12294
   Greco JA, 2008, ANN PLAS SURG, V61, P235, DOI 10.1097/SAP.0b013e318166d351
   Horch RE, 2014, J CELL MOL MED, V18, P1478, DOI 10.1111/jcmm.12296
   Horch RE, 2013, J CELL MOL MED, V17, P1197, DOI 10.1111/jcmm.12130
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Kilpadi DV, 2014, AESTHET PLAST SURG, V38, P767, DOI 10.1007/s00266-014-0339-x
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Kubek E.W., 2014, MICROBIAL PATHOGENS, P1833
   Leffler M, 2011, J CELL MOL MED, V15, P1564, DOI 10.1111/j.1582-4934.2010.01147.x
   Lewis LS, 2014, GYNECOL ONCOL, V132, P684, DOI 10.1016/j.ygyno.2014.01.014
   Ludolph I, 2016, INT WOUND J, V13, P77, DOI 10.1111/iwj.12235
   Mark KS, 2014, SURG INNOV, V21, P345, DOI 10.1177/1553350613503736
   Masden D, 2012, ANN SURG, V255, P1043, DOI 10.1097/SLA.0b013e3182501bae
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Pauli EM, 2013, SURG INFECT, V14, P270, DOI 10.1089/sur.2012.059
   Schmedes GW, 2012, OTOLARYNG HEAD NECK, V147, P1049, DOI 10.1177/0194599812459015
   Stanger KM, 2015, INT WOUND J, V12, P443, DOI 10.1111/iwj.12133
   Stannard JP, 2012, INT WOUND J, V9, P32, DOI 10.1111/j.1742-481X.2012.01017.x
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Strobel LA, 2014, J TISSUE ENG REGEN M, V8, P176, DOI 10.1002/term.1511
   van der Beek ESJ, 2011, OBESITY FACTS, V4, P61, DOI 10.1159/000324567
   Weir G, 2014, INT WOUND J, V11, P10, DOI 10.1111/iwj.12261
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Zannis J, 2009, ANN PLAS SURG, V62, P407, DOI 10.1097/SAP.0b013e3181881b29
NR 40
TC 66
Z9 77
U1 2
U2 22
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD APR
PY 2015
VL 24
IS 4
SU S
BP 21
EP 28
DI 10.12968/jowc.2015.24.Sup4b.21
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA CG1YK
UT WOS:000353071900004
PM 25853645
DA 2026-07-24
ER

PT J
AU Sahin, I
   Ozturk, S
   Deveci, M
   Ural, AU
   Onguru, O
   Isik, S
AF Sahin, Ismail
   Ozturk, Sinan
   Deveci, Mustafa
   Ural, Ali Ugur
   Onguru, Onder
   Isik, Selcuk
TI Experimental assessment of the neo-vascularisation of acellular dermal
   matrix in the wound bed pretreated with mesenchymal stem cell under
   subatmospheric pressure
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article; Proceedings Paper
CT 80th Annual Meeting of the American-Society-of-Plastic-Surgeons (ASPS)
CY SEP 23-27, 2011
CL Denver, CO
SP Amer Soc Plast Surg
DE Acellular dermal matrix; Mesenchymal stem cells; Negative pressure wound
   therapy; Neo-vascularisation
ID ENDOTHELIAL GROWTH-FACTOR; IMPROVING GRAFT-SURVIVAL; ASSISTED CLOSURE
   DEVICE; SECURING SKIN-GRAFTS; RECONSTRUCTION; ANGIOGENESIS; REPLACEMENT;
   DRESSINGS; BOLSTER; MODEL
AB Neo-vascularisation of the acellular dermal matrix (ADM) is an essential procedure if a full-thickness wound is closed with ADM and skin is grafted over the ADM.
   In this study, we aimed to improve the neo-vascularisation of ADM by combining the effects of negative pressure wound therapy (NPWT) and mesenchymal stem cells (MSCs) on angiogenesis. In this study, 28 female Sprague-Dawley rats were used and divided into four groups. Full-thickness dorsal skin defects were created in 2 x 2 cm dimensions. The wounds were treated with only the ADM in group 1, the ADM and NPWT in group 2, the ADM and MSCs in group 3 and the ADM, NPWT and MSCs in group 4. By the ninth day of surgery, the excisional biopsy samples were histologically examined to identify the rates of ADM adherence to the recipient bed; the newly formed blood vessels which penetrate the ADM vertically and vascularisation were evaluated by immunohistochemical staining.
   The graft adherence rates were higher in group 4 than in the other groups statistically, p = 0.003. The numbers of cluster of differentiation 31 (CD31)-stained newly formed microvessels were higher in group 4 than in the other groups statistically, p < 0.05. All subjects in group 4 had the vertical vessels in normal calibration with open lumen vessels which penetrate the ADM.
   These findings suggest that MSC transplantation induces angiogenesis more efficiently than NPWT. The combination of the NPWT with MSC in this study has shown a synergistic effect on angiogenesis and has affected the neo-vascularisation of the ADM significantly. (C) 2013 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Sahin, Ismail; Ozturk, Sinan; Isik, Selcuk] Gulhane Mil Med Acad, Dept Plast & Reconstruct Surg, TR-06010 Ankara, Turkey.
   [Deveci, Mustafa] Numune Egitim & Arastirma Hastanesi, Dept Plast & Reconstruct Surg, Ankara, Turkey.
   [Ural, Ali Ugur] Bayindir Hosp, Dept Haematol, Ankara, Turkey.
   [Onguru, Onder] Gulhane Mil Med Acad, Dept Pathol, TR-06010 Ankara, Turkey.
C3 Gulhane Training & Research Hospital; Ankara Numune Training & Research
   Hospital; Bayindir Hastanesi; Bayindir Health Group; Gulhane Training &
   Research Hospital
RP Sahin, I (通讯作者)，Gulhane Mil Med Acad, Dept Plast & Reconstruct Surg, TR-06010 Ankara, Turkey.
EM drismailsahin@yahoo.com
RI /AAJ-4406-2021
CR Altman AM, 2008, AESTHET PLAST SURG, V32, P698, DOI 10.1007/s00266-008-9159-1
   Askari M, 2011, PLAST RECONSTR SURG, V127, P1593, DOI 10.1097/PRS.0b013e31820a6511
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Capla JM, 2006, PLAST RECONSTR SURG, V117, P836, DOI 10.1097/01.prs.0000201459.91559.7f
   Chen LW, 2008, PLOS ONE, V3, DOI 10.1371/journal.pone.0001886
   Chern PL, 2009, DERMATOL SURG, V35, P891, DOI 10.1111/j.1524-4725.2009.01153.x
   Chung S, 2003, PLAST RECONSTR SURG, V111, P225, DOI 10.1097/01.PRS.0000034934.05304.ED
   Colwell AS, 2011, PLAST RECONSTR SURG, V128, P1170, DOI 10.1097/PRS.0b013e318230c2f6
   Eisenbud D, 2004, WOUNDS, V16, P2
   FALCO NA, 1992, MICROSURG, V13, P249, DOI 10.1002/micr.1920130511
   FERRARA N, 1993, TRENDS CARDIOVAS MED, V3, P244, DOI 10.1016/1050-1738(93)90046-9
   Huang SP, 2012, ANN PLAS SURG, V69, P656, DOI 10.1097/SAP.0b013e318273f909
   Lindenblatt N, 2008, PLAST RECONSTR SURG, V122, P1669, DOI 10.1097/PRS.0b013e31818cbeb1
   Menn ZK, 2012, J RECONSTR MICROSURG, V28, P139, DOI 10.1055/s-0031-1289167
   Metcalfe AD, 2007, J R SOC INTERFACE, V4, P413, DOI 10.1098/rsif.2006.0179
   Nie CL, 2015, J TISSUE ENG REGEN M, V9, P224, DOI 10.1002/term.1622
   Orbay H, 2011, AESTHET PLAST SURG, V35, P756, DOI 10.1007/s00266-011-9683-2
   Sbitany H, 2011, PLAST RECONSTR SURG, V128, P1162, DOI 10.1097/PRS.0b013e318230c29e
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Tang B, 2011, PLAST RECONSTR SURG, V127, P1533, DOI 10.1097/PRS.0b013e31820a63e8
   Weinfeld AB, 2005, ANN PLAS SURG, V54, P178, DOI 10.1097/01.sap.0000143606.39693.3f
   Wong AK, 2008, PLAST RECONSTR SURG, V121, P1144, DOI 10.1097/01.prs.0000302505.43942.07
   Yim H, 2010, BURNS, V36, P322, DOI 10.1016/j.burns.2009.10.018
   Zachary I, 1998, INT J BIOCHEM CELL B, V30, P1169, DOI 10.1016/S1357-2725(98)00082-X
   Zhong T, 2011, J PLAST RECONSTR AES, V64, P1562, DOI 10.1016/j.bjps.2011.04.035
NR 25
TC 14
Z9 16
U1 0
U2 18
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD JAN
PY 2014
VL 67
IS 1
BP 107
EP 114
DI 10.1016/j.bjps.2013.08.001
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 282XU
UT WOS:000329208900025
PM 24055332
DA 2026-07-24
ER

PT J
AU Lau, NS
   Ahmadi, N
   Verran, D
AF Lau, Ngee-Soon
   Ahmadi, Nima
   Verran, Deborah
TI Abdominal wall complications following renal transplantation in adult
   recipients - factors associated with interventional management in one
   unit
SO BMC SURGERY
LA English
DT Article
DE Wound complications; Renal transplantation; Negative pressure wound
   therapy
ID PRESSURE WOUND THERAPY; SURGICAL SITE INFECTION; BODY-MASS INDEX;
   KIDNEY-TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS; HEALING
   COMPLICATIONS; DIABETES-MELLITUS; RISK-FACTORS; OBESITY; INCISION
AB Background: Abdominal wall surgical site complications following renal transplantation can be challenging to manage. A sub-group of these recipients will require operative management or advanced wound care such as negative pressure wound therapy (NPWT). The aim of this study was to determine if there were any preoperative, intraoperative and postoperative characteristics in our recipients' cohort which were associated with the requirement for such interventions.
   Methods: A retrospective review of medical records was performed for all recipients who sustained abdominal wall complications following renal transplantation at our centre from 2006 to 2016.
   Results: A total of 64/828 recipients (7.7%) had abdominal wall complications. The mean weight for these patients was 84.9 kg (+/- 16.6 kg) and the mean body mass index was 30.2 (+/- 5.1). Forty-five recipients (70%) had a superficial wound dehiscence while nine (14%) had a complete fascial dehiscence. Operative intervention was required in 13/64 patients (20%) and was more likely to be required in the presence of a fascial dehiscence (9/9, 100%) or a wound collection (10/31, 32%) (p < 0.001, p = 0.021). NPWT was used in 17/64 patients (27%) and was more commonly required in patients with diabetes mellitus (10/24, 42%), a complete fascial dehiscence (5/9, 56%) or evidence of infection (16/44, 36%) (p = 0.039, p = 0.034, p = 0.008).
   Conclusions: The requirement for either operative management or the use of NPWT in the management of abdominal wall complications following renal transplantation in our experience was more common in recipients with diabetes mellitus, and in the setting of either complete fascial dehiscence, abdominal wall wound collections and/or infection.
C1 [Lau, Ngee-Soon; Ahmadi, Nima; Verran, Deborah] Royal Prince Alfred Hosp, Dept Transplant Surg, Sydney, NSW, Australia.
C3 NSW Health; Royal Prince Alfred Hospital; University of Sydney
RP Lau, NS (通讯作者)，Royal Prince Alfred Hosp, Dept Transplant Surg, Sydney, NSW, Australia.
EM ngeesoon.lau@health.nsw.gov.au
RI Verran, Deborah/V-3954-2019; Ahmadi, Nima/AAE-1158-2019
OI Ahmadi, Nima/0000-0003-0100-1200
CR ANZDATA Registry, 2014, INC END STAG KIDN DI
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Australian Bureau of Statistics, 2014, NON TRADITIONAL REF
   Barba J, 2012, TRANSPL P, V44, P1275, DOI 10.1016/j.transproceed.2012.01.112
   Barba J, 2013, SCAND J UROL, V47, P63, DOI 10.3109/00365599.2012.700945
   Bozkurt B, 2015, TRANSPL P, V47, P1515, DOI 10.1016/j.transproceed.2015.04.057
   Dean PG, 2004, TRANSPLANTATION, V77, P1555, DOI 10.1097/01.TP.0000123082.31092.53
   Doyle SL, 2010, OBES REV, V11, P875, DOI 10.1111/j.1467-789X.2009.00700.x
   Fockens MM, 2015, PROG TRANSPLANT, V25, P45, DOI 10.7182/pit2015812
   Franchin M, 2014, CASE REPORTS TRANSPL, P8
   Greenhalgh DG, 2003, CLIN PLAST SURG, V30, P37, DOI 10.1016/S0094-1298(02)00066-4
   Harris AD, 2015, INFECT CONT HOSP EP, V36, P417, DOI 10.1017/ice.2014.77
   Heap S, 2010, AM J TRANSPLANT, V10, P2370, DOI 10.1111/j.1600-6143.2010.03237.x
   Hernández D, 2006, NEPHROL DIAL TRANSPL, V21, P2908, DOI 10.1093/ndt/gfl338
   HJORTRUP A, 1985, BRIT J SURG, V72, P783, DOI 10.1002/bjs.1800721005
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Johnson DW, 2002, TRANSPLANTATION, V74, P675, DOI 10.1097/00007890-200209150-00015
   Kuo JH, 2012, J SURG RES, V173, P216, DOI 10.1016/j.jss.2011.05.030
   Lafranca JA, 2015, BMC MED, V13, DOI 10.1186/s12916-015-0340-5
   Lynch RJ, 2009, ANN SURG, V250, P1014, DOI 10.1097/SLA.0b013e3181b4ee9a
   Markic Dean, 2014, Coll Antropol, V38, P1199
   Mehrabi A, 2006, CLIN TRANSPLANT, V20, P97, DOI 10.1111/j.1399-0012.2006.00608.x
   Nashan B, 2012, TRANSPLANTATION, V94, P547, DOI 10.1097/TP.0b013e3182551021
   Orlic L, 2015, INT J CLIN PRACT, V69, P1357, DOI 10.1111/ijcp.12715
   Ortiz J, 2011, AM J TRANSPLANT, V11, P412, DOI 10.1111/j.1600-6143.2010.03362.x
   Pavlidis TE, 2001, EUR J SURG, V167, P351
   Roine E, 2010, TRANSPL P, V42, P2542, DOI 10.1016/j.transproceed.2010.05.162
   Santangelo M, 2006, TRANSPLANT P, V38, P1044, DOI 10.1016/j.transproceed.2006.03.005
   Santangelo M, 2009, TRANSPL P, V41, P1221, DOI 10.1016/j.transproceed.2009.03.098
   Shrestha B M, 2007, Kathmandu Univ Med J (KUMJ), V5, P4
   Shrestha Badri Man, 2016, World J Transplant, V6, P767, DOI [10.5500/wjt.v6.i4.767, 10.5500/wjt.v6.i4.767]
   Singh D, 2005, TRANSPL P, V37, P717, DOI 10.1016/j.transproceed.2004.12.033
   Taha M, 2017, CLIN TRANSPLANT, V31, DOI 10.1111/ctr.12960
   Tan A, 2014, INT J SURG, V12, P26, DOI 10.1016/j.ijsu.2013.11.002
   Treckmann JW, 2011, HEPATO-GASTROENTEROL, V58, P738
   Zhen ZJ, 2011, INT J SURG, V9, P378, DOI 10.1016/j.ijsu.2011.02.012
   Zrim S, 2012, NEPHROLOGY, V17, P582, DOI 10.1111/j.1440-1797.2012.01621.x
NR 38
TC 15
Z9 17
U1 0
U2 1
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1471-2482
J9 BMC SURG
JI BMC Surg.
PD JAN 21
PY 2019
VL 19
AR 10
DI 10.1186/s12893-019-0468-x
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HK5VD
UT WOS:000458035600001
PM 30665387
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Yin, RY
   Gursky, A
   Falade, I
   Knox, J
   Gomez-Sanchez, C
   Soroudi, D
   Piper, M
   Hoffman, W
   Hansen, SL
AF Yin, Raymond
   Gursky, Alexis
   Falade, Israel
   Knox, Jacquelyn
   Gomez-Sanchez, Clara
   Soroudi, Daniel
   Piper, Merisa
   Hoffman, William
   Hansen, Scott L.
TI The Utility of Prevena Negative Pressure Wound Therapy on Groin
   Incisions for Critical Limb-Threatening Ischemia A Single Institution
   Experience
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE Prevena; iNPWT; critical limb-threatening ischemia; plastic surgery
ID PROPHYLACTIC MUSCLE FLAPS; INFECTION; RECONSTRUCTION; COMPLICATIONS;
   MANAGEMENT
AB Background: Incisional negative pressure wound therapy (iNPWT) is an adjunctive treatment that uses constant negative pressure suction to facilitate healing. The utility of this treatment modality on vascular operations for critical limb-threatening ischemia (CLTI) has yet to be elucidated. This study compares the incidence of postoperative wound complications between the Prevena Incision Management System, a type of iNPWT, and standard wound dressings for vascular patients who also underwent plastic surgery closure of groin incisions for CLTI. Method: We performed a retrospective cohort study of 40 patients with CLTI who underwent 53 open vascular surgeries with subsequent sartorius muscle flap closure. Patient demographics, intraoperative details, and wound complications were measured from 2015 to 2018 at the University of California San Francisco. Two cohorts were generated based on the modality of postoperative wound management and compared on wound healing outcomes. Results: Of the 53 groin incisions, 29 were managed with standard dressings, and 24 received iNPWT. Patient demographics, comorbidities, and operative characteristics were similar between the 2 groups. Patients who received iNPWT had a significantly lower rate of infection (8.33% vs 31.0%, P = 0.04) and dehiscence (0% vs 41.3%, P < 0.01). Furthermore, the iNPWT group had a significantly lower rate of reoperation (0% vs 17.2%, P = 0.03) for wound complications within 30 days compared with the control group and a moderately reduced rate of readmission (4.17% vs 20.7%, P = 0.08). Conclusions: Rates of infection, reoperation, and dehiscence were significantly reduced in patients whose groin incisions were managed with iNPWT compared with standard wound care. Readmission rates were also decreased, but this difference was not statistically significant. Our results suggest that implementing iNPWT for the management of groin incisions, particularly in patients undergoing vascular operations for CLTI, may significantly improve clinical outcomes.
C1 [Yin, Raymond; Falade, Israel; Soroudi, Daniel] Univ Calif San Francisco, Sch Med, San Francisco, CA USA.
   [Gursky, Alexis] SUNY Upstate Med Univ, Norton Coll Med, Syracuse, NY USA.
   [Knox, Jacquelyn; Piper, Merisa; Hoffman, William; Hansen, Scott L.] Univ Calif San Francisco, Div Plast & Reconstruct Surg, San Francisco, CA USA.
   [Gomez-Sanchez, Clara] Univ Calif San Francisco, Dept Surg, Div Vasc & Endovasc Surg, San Francisco, CA USA.
   [Piper, Merisa] Univ Calif San Francisco, Div Plast & Reconstruct Surg, Dept Surg, 350 Parnassus Ave,M593, San Francisco, CA 94143 USA.
C3 University of California System; University of California San Francisco;
   State University of New York (SUNY) System; SUNY Upstate Medical
   University; University of California System; University of California
   San Francisco; University of California System; University of California
   San Francisco; University of California System; University of California
   San Francisco
RP Piper, M (通讯作者)，Univ Calif San Francisco, Div Plast & Reconstruct Surg, Dept Surg, 350 Parnassus Ave,M593, San Francisco, CA 94143 USA.
EM raymond.yin@ucsf.edu; alexis.gursky@gmail.com; israel.falade@ucsf.edu;
   jacquelyn.knox@ucsf.edu; clara.gomez-sanchez@ucsf.edu;
   daniel.soroudi@ucsf.edu; Merisa.Piper@ucsf.edu;
   william.hoffman@ucsf.edu; scott.hansen@ucsf.edu
RI ; Falade, Israel/JUU-8119-2023
OI Soroudi, Daniel/0009-0001-4022-7555; Piper, Merisa/0000-0002-9458-3782;
   Gursky, Alexis/0000-0002-2479-9828; 
CR Calligaro K D, 1994, Ann Vasc Surg, V8, P31, DOI 10.1007/BF02133403
   Cheung DC, 2022, DIS COLON RECTUM, V65, P767, DOI 10.1097/DCR.0000000000002154
   Colli A, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-160
   Condé-Green A, 2013, ANN PLAS SURG, V71, P394, DOI 10.1097/SAP.0b013e31824c9073
   Damrauer SM, 2015, J VASC SURG, V62, P1192, DOI 10.1016/j.jvs.2015.06.213
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   Duff S, 2019, VASC HEALTH RISK MAN, V15, P187, DOI 10.2147/VHRM.S209241
   Engelhardt M, 2018, INT WOUND J, V15, P327, DOI 10.1111/iwj.12848
   Engin C, 2005, TEX HEART I J, V32, P529
   EVANS GRD, 1993, PLAST RECONSTR SURG, V91, P1294, DOI 10.1097/00006534-199306000-00016
   Fischer JP, 2012, J VASC SURG, V55, P1081, DOI 10.1016/j.jvs.2011.10.110
   Frazee R, 2018, J AM COLL SURGEONS, V226, P507, DOI 10.1016/j.jamcollsurg.2017.12.008
   Gerhard-Herman MD, 2017, J AM COLL CARDIOL, V69, pE71, DOI [10.1016/j.jacc.2016.11.007, 10.1161/CIR.0000000000000471]
   Gulati A, 2015, J CARDIOVASC SURG, V56, P775
   Heard C, 2017, J TISSUE VIABILITY, V26, P79, DOI 10.1016/j.jtv.2016.06.001
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Labler L, 2009, J TRAUMA, V66, P749, DOI 10.1097/TA.0b013e318171971a
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Lodin D, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9389
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Ploeg AJ, 2009, AM J SURG, V197, P747, DOI 10.1016/j.amjsurg.2008.04.014
   Stannard JP, 2012, INT WOUND J, V9, P32, DOI 10.1111/j.1742-481X.2012.01017.x
   Stewart AH, 2007, J VASC SURG, V46, P148, DOI 10.1016/j.jvs.2007.02.065
   Sundby OH, 2016, PHYSIOL REP, V4, DOI 10.14814/phy2.12998
   Swinnen J, 2010, ANN VASC SURG, V24, P336, DOI 10.1016/j.avsg.2009.07.020
   Wallace AB, 2022, ANN VASC SURG, V78, P77, DOI 10.1016/j.avsg.2021.05.049
NR 27
TC 1
Z9 1
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD MAY
PY 2024
VL 92
IS 5S
SU 3
BP S331
EP S335
DI 10.1097/SAP.0000000000003802
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA OZ3R0
UT WOS:001211064500002
PM 38689414
DA 2026-07-24
ER

PT J
AU Gonzalez, GA
   Castagno, C
   Carter, J
   Chellappan, B
   Taupin, P
AF Gonzalez, Gilberto A.
   Castagno, Christopher
   Carter, Jordan
   Chellappan, Brinda
   Taupin, Philippe
TI Negative pressure wound therapy on complex extremity wounds requiring
   coverage with a meshed bilayer wound matrix: a retrospective analysis
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE acellular dermal matrix; diabetes; exposed structure; infection; Integra
   Meshed Bilayer Wound Matrix; postoperative complications; retrospective
   review; wound; wound care; wound dressing; wound healing
ID DERMAL REGENERATION TEMPLATE; SCALP RECONSTRUCTION; SKIN SUBSTITUTES;
   ARTIFICIAL SKIN; TISSUE; INTEGRA; PATIENT
AB Objective: The treatment of complex extremity wounds is technically challenging. In this 5-year retrospective review, we compared the use of Integra Meshed Bilayer Wound Matrix (IMBWM; Integra LifeSciences, US) followed by a split-thickness skin graft (STSG) combined with negative pressure wound therapy (NPWT) versus IMBWM followed by STSG alone for the management of these wounds.
   Method: Data from patients undergoing management using IMBWM for a complex extremity wound coverage were collected.
   Results: Among the 109 patients studied, the wounds of 62 patients were managed using IMBWM and NPWT, and 47 were managed using IMBWM alone. The most common aetiology of these injuries was trauma. Wound size and location were similar for each group, ranging in size from 2-30cm(2) and being primarily on the forearm, followed by the leg and arm. There was a significantly greater take of the IMBWM+STSG with NPWT (96.8%) compared to without NPWT (85.1%, p=0.03). There were significantly fewer reapplications of the dermal matrix required in the NPWT group (3.2%) versus the non-NPWT group (14.9%, p=0.03). There were significantly fewer postoperative complications, prior to STSG, in the NPWT group (3.2%) versus the non-NPWT group (14.9%, p=0.03).
   Conclusion: The combination of IMBWM with NPWT leads to a higher success rate, and can reduce the number of dermal matrix reapplications and postoperative complications, in the setting of complex extremity wounds. The use of IMBWM in combination with NPWT has the potential to improve both surgical procedures and patient outcomes in this setting.
C1 [Gonzalez, Gilberto A.] Texas Tech Univ Hlth Sci Ctr, Orthoped Surg, El Paso, TX 79905 USA.
   [Castagno, Christopher; Carter, Jordan; Chellappan, Brinda] Texas Tech Univ Hlth Sci Ctr, El Paso, TX USA.
   [Taupin, Philippe] Integra LifeSci, Med Affairs, Princeton, NJ USA.
C3 Texas Tech University System; Texas Tech University Health Sciences
   Center El Paso; Texas Tech University System; Texas Tech University
   Health Sciences Center El Paso
RP Gonzalez, GA (通讯作者)，Texas Tech Univ Hlth Sci Ctr, Orthoped Surg, El Paso, TX 79905 USA.
EM gilberto.a.gonzalez@ttuhsc.edu
OI Carter, Jordan/0000-0001-8320-1251
CR BURKE JF, 1981, ANN SURG, V194, P413, DOI 10.1097/00000658-198110000-00005
   Crapo PM, 2011, BIOMATERIALS, V32, P3233, DOI 10.1016/j.biomaterials.2011.01.057
   Cunningham T, 2014, DERMATOL SURG, V40, pS120, DOI 10.1097/DSS.0000000000000113
   Diehm YF, 2021, J PLAST RECONSTR AES, V74, P357, DOI 10.1016/j.bjps.2020.08.041
   Fischer JP, 2013, J RECONSTR MICROSURG, V29, P89, DOI 10.1055/s-0032-1329918
   Gao JR, 2021, J ADV NURS, V77, P3980, DOI 10.1111/jan.14876
   Gonzalez Alana I, 2013, Ann Burns Fire Disasters, V26, P90
   Helgeson MD, 2007, J ORTHOP TRAUMA, V21, P394, DOI 10.1097/BOT.0b013e318070c028
   Hughes OB, 2016, PLAST RECONSTR SURG, V138, p138S, DOI 10.1097/PRS.0000000000002643
   Hussussian CJ, 2002, PLAST RECONSTR SURG, V109, P1828, DOI 10.1097/00006534-200205000-00008
   Hutchison RL, 2013, J WOUND CARE, V22, P708, DOI 10.12968/jowc.2013.22.12.708
   Jeschke MG, 2004, PLAST RECONSTR SURG, V113, P525, DOI 10.1097/01.PRS.0000100813.39746.5A
   Jordan Daniel J, 2014, Open Orthop J, V8, P423, DOI 10.2174/1874325001408010423
   Kantak NA, 2017, CLIN PLAST SURG, V44, P671, DOI 10.1016/j.cps.2017.02.023
   Konofaos P, 2014, J CRANIOFAC SURG, V25, P1362, DOI 10.1097/SCS.0000000000000822
   Kozak GM, 2020, PLAST RECONSTR SURG, V145, p608E, DOI 10.1097/PRS.0000000000006589
   Lalezari S, 2017, INT WOUND J, V14, P649, DOI 10.1111/iwj.12658
   McEwan W, 2004, BURNS, V30, P259, DOI 10.1016/j.burns.2003.11.011
   Milcheski DA, 2014, PRS-GLOB OPEN, V2, DOI 10.1097/GOX.0000000000000108
   Moiemen NS, 2010, BURNS, V36, P764, DOI 10.1016/j.burns.2010.04.011
   Moiemen NS, 2001, PLAST RECONSTR SURG, V108, P93, DOI 10.1097/00006534-200107000-00015
   Vana LPM, 2020, BURNS, V46, P596, DOI 10.1016/j.burns.2019.09.005
   Napolitano RJ, 2018, CUREUS J MED SCIENCE, V10, DOI 10.7759/cureus.3443
   Park CA, 2009, ANN PLAS SURG, V62, P164, DOI 10.1097/SAP.0b013e31817d87cb
   Robert N, 2017, ORTHOP TRAUMATOL-SUR, V103, pS99, DOI 10.1016/j.otsr.2016.04.018
   Rosenbaum AJ, 2018, J AM ACAD ORTHOP SUR, V26, P833, DOI 10.5435/JAAOS-D-17-00024
   Saab IR, 2014, J WOUND CARE, V23, pS5, DOI 10.12968/jowc.2014.23.Sup10.S5
   Satteson ES, 2015, J CRANIOFAC SURG, V26, pE599, DOI 10.1097/SCS.0000000000002047
   Schiestl C, 2011, EUR J PEDIATR SURG, V21, P106, DOI 10.1055/s-0030-1267234
   Shah A, 2022, CASE REP PLAST SURG, V9, P7, DOI 10.1080/23320885.2021.2011289
   Shakir S, 2020, PLAST RECONSTR SURG, V145, P813, DOI 10.1097/PRS.0000000000006609
   Shevchenko RV, 2010, J R SOC INTERFACE, V7, P229, DOI 10.1098/rsif.2009.0403
   Shridharani SM, 2012, PLAST RECONSTR SURG, V130, p35S, DOI 10.1097/PRS.0b013e31825eff7a
   Stiefel D, 2009, J PEDIATR SURG, V44, P575, DOI 10.1016/j.jpedsurg.2008.07.006
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Watts V, 2019, J ORAL MAXIL SURG, V77, P338, DOI 10.1016/j.joms.2018.08.022
   Yannas Ioannis V., 1998, Wound Repair and Regeneration, V6, P518, DOI 10.1046/j.1524-475X.1998.60604.x
   YANNAS IV, 1982, SCIENCE, V215, P174, DOI 10.1126/science.7031899
NR 38
TC 6
Z9 6
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD SEP
PY 2022
VL 31
IS 9
SU S
BP S8
EP S15
DI 10.12968/jowc.2022.31.Sup9.S8
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 4R2KF
UT WOS:000856597000003
PM 36113853
DA 2026-07-24
ER

PT J
AU Chatterjee, R
   Riddle, TM
   Poskarbiewicz, MK
   Babcock, GF
AF Chatterjee, Ranjit
   Riddle, Tara M.
   Poskarbiewicz, Melisa K.
   Babcock, George F.
TI A Novel Approach to Negative Pressure Wound Therapy: Use of High Suction
   Capillary Device to Improve Wound Healing
SO MILITARY MEDICINE
LA English
DT Article
AB Introduction:
   Negative Pressure Wound Therapy (NPWT) is a procedure used for nonhealing wounds. In NPWT, a special sealed dressing of large cell foam (>400 mu m) or gauze is connected to a pump. Most commonly, negative pressures between -10 and -125 millimeters of mercury (mm Hg) are used. The mechanism of healing is unknown but maybe attributable to removal of the exudate and bacteria, and the stimulation of tissue repair through microdeformation. Reticulated foams with micron-size open cells, Capillary Suction Devices (CSD; 100 to 5 mu m) exert capillary suction between 10 and 70 mm of Hg with a multilayered foam dressing.
   Materials and Methods:
   Yorkshire pigs received 5 surgical excision wounds, 3 cm(2), on each side of the back. The wounds were covered with a NPWT dressing (110 mm Hg negative pressure by a pump), CSD with capillary suctions of 30 mm Hg (CSD-30) and 70 mm Hg (CSD-70), and a conventional gauze dressing. The wounds were measured on day 2, and then every 4-5 days thereafter; the total fluid collected by the various dressing over time.
   Results:
   By post-wound day 20, the wounds treated with CSD-70 and NPWT were 100% closed while the wounds treated with CSD-30 and gauze were 65% and 45%, respectively. This indicated comparable wound closure efficacies for CSD-70 and NPWT. The average total fluid uptake measured in grams dry weight were similar for CSD-70 and NPWT, 36 and 38 g, respectively, while the values were 24 g for CSD-30 and 12 g for gauze. However, the maximum fluid uptake observed at day 2 indicated that CSD-70 and CSD 30, 24 and 14 g, respectively, were superior to NPWT and gauze 12 and 7 g, respectively.
   Conclusion:
   This data indicate comparable wound closure efficacies for CSD-70 and NPWT. It is felt that CSD is an effective, safe, and lower cost alternative to vacuum-assisted NPWT.
C1 [Chatterjee, Ranjit] Dristi LLC, Cincinnati, OH 45243 USA.
   [Riddle, Tara M.; Poskarbiewicz, Melisa K.; Babcock, George F.] Univ Cincinnati, Dept Surg, 231 Bethesda Ave, Cincinnati, OH 45267 USA.
   [Babcock, George F.] Shriners Hosp Children, Cincinnati, OH 45229 USA.
C3 University System of Ohio; University of Cincinnati
RP Chatterjee, R (通讯作者)，Dristi LLC, Cincinnati, OH 45243 USA.
RI /K-9469-2019
FU Shriners Hospitals for Children [SHCC 871000]
FX This study was supported in part by a grant from Shriners Hospitals for
   Children (#SHCC 871000).
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong David G, 2002, Ostomy Wound Manage, V48, P64
   Boateng J, 2015, J PHARM SCI-US, V104, P3653, DOI 10.1002/jps.24610
   Borgquist O, 2011, PLAST RECONSTR SURG, V127, P551, DOI 10.1097/PRS.0b013e3181fed52a
   Contractor D, 2008, J ORTHOP TRAUMA, V22, pS167, DOI 10.1097/BOT.0b013e318188e295
   Davis K, 2013, WOUND REPAIR REGEN, V21, P869, DOI 10.1111/wrr.12104
   Davis KE, 2013, WOUND REPAIR REGEN, V21, P740, DOI 10.1111/wrr.12079
   Debeer S, 2013, EUR J DERMATOL, V23, P456, DOI 10.1684/ejd.2013.2060
   Dumville JC, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006215.pub4
   Fleck CA, 2004, WOUND CARE, V3, P20
   Gohel MS, 2008, J VASC SURG, V48, P1272, DOI 10.1016/j.jvs.2008.06.042
   Hinck D, 2010, MIL MED, V175, P173, DOI 10.7205/MILMED-D-09-00075
   Hoeller M, 2014, BURNS, V40, P1116, DOI 10.1016/j.burns.2013.12.007
   Honnegowda TM, 2016, INT WOUND J, V13, P791, DOI 10.1111/iwj.12384
   Iheozor-Ejiofor Z, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD012522.pub2
   Jentzsch T, 2017, ARCH ORTHOP TRAUM SU, V137, P55, DOI 10.1007/s00402-016-2600-z
   Kamolz L P, 2014, Ann Burns Fire Disasters, V27, P141
   Liu Y, 2018, INT J LOW EXTR WOUND, V17, P144, DOI 10.1177/1534734618794856
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   Moffatt CJ, 2019, J WOUND CARE, V28, P738, DOI 10.12968/jowc.2019.28.11.738
   Moor AN, 2009, WOUND REPAIR REGEN, V17, P832, DOI 10.1111/j.1524-475X.2009.00547.x
   O'Brien K, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0113956
   Petrou S, 2019, BONE JOINT J, V101B, P1392, DOI 10.1302/0301-620X.101B11.BJJ-2018-1228.R2
   Pierce GF, 2001, AM J PATHOL, V159, P399, DOI 10.1016/S0002-9440(10)61709-9
   Qiu E, 2018, J PLAST SURG HAND SU, V52, P259, DOI 10.1080/2000656X.2018.1470979
   Rayment EA, 2008, BRIT J DERMATOL, V158, P951, DOI 10.1111/j.1365-2133.2008.08462.x
   Wasiak J, 2007, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006215
NR 27
TC 2
Z9 2
U1 0
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0026-4075
EI 1930-613X
J9 MIL MED
JI Milit. Med.
PD JAN-FEB
PY 2021
VL 186
SU 1
BP 364
EP 369
DI 10.1093/milmed/usaa276
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA RJ0XS
UT WOS:000637327600052
PM 33499483
OA Bronze
DA 2026-07-24
ER

PT J
AU Redfern, RE
   Cameron-Ruetz, C
   O'Drobinak, SK
   Chen, JT
   Beer, KJ
AF Redfern, Roberta E.
   Cameron-Ruetz, Claire
   O'Drobinak, Simone K.
   Chen, John T.
   Beer, Karl J.
TI Closed Incision Negative Pressure Therapy Effects on Postoperative
   Infection and Surgical Site Complication After Total Hip and Knee
   Arthroplasty
SO JOURNAL OF ARTHROPLASTY
LA English
DT Article
DE primary hip arthroplasty; primary knee arthroplasty; surgical site
   infection; hematoma; seroma; negative pressure wound therapy
ID PROSPECTIVE RANDOMIZED-TRIAL; CLOSURE WOUND THERAPY; MANAGEMENT-SYSTEM;
   1ST EXPERIENCE; REVISION HIP; SURGERY; PREVENTION; FRACTURES; DRESSINGS;
   BURDEN
AB Background: The aim of this study is to determine whether negative pressure wound therapy, used prophylactically in clean surgical incisions, reduces surgical site infection, hematoma, and seroma after total joint replacement.
   Methods: A single center, open-label study with a prospective cohort of patients undergoing primary total knee arthroplasty or total hip arthroplasty treated with closed incision negative pressure therapy (ciNPT) of clean surgical wounds was conducted. One hundred ninety-six incisions treated with ciNPT in 192 patients were compared with a historical control group of 400 patients treated with traditional gauze dressing. The rates of clinically significant hematoma, seroma, dehiscence, surgical site infection, and complication were compared using univariate analyses and multiple logistic regression.
   Results: The rate of deep infection was unchanged in the ciNPT group compared with control (1.0% vs 1.25%); however, the overall rate of infection (including superficial wound infection) decreased significantly (3.5% vs 1.0%, P = .04). Overall complication rate was lower in the ciNPT group than controls (1.5% vs 5.5%, P = .02). Upon logistic regression, only treatment group was associated with complication; patients treated with ciNPT were about 4 times less likely to experience a surgical site complication compared with control (P = .0277, odds ratio 4.251, 95% confidence interval 1.172-15.414).
   Conclusion: ciNPT for total knee arthroplasty and total hip arthroplasty in a comprehensive patient population reduced overall incidence of complication, but did not significantly impact the rate of deep infection. Further research to determine clinical and economic advantages of routine use of ciNPT in total joint arthroplasty is warranted. (c) 2017 Elsevier Inc. All rights reserved.
C1 [Redfern, Roberta E.] ProMed Toledo Hosp, ProMed Res, Toledo, OH USA.
   [Cameron-Ruetz, Claire] Univ Toledo, Coll Nat Sci & Math, Toledo, OH USA.
   [O'Drobinak, Simone K.; Beer, Karl J.] ProMed Toledo Hosp, Wildwood Orthoped & Spine Inst, Dept Orthoped Surg, 2865 N Reynolds Rd,160, Toledo, OH 43615 USA.
   [Chen, John T.] Bowling Green State Univ, Dept Math & Stat, Bowling Green, OH 43403 USA.
C3 University System of Ohio; University of Toledo; University System of
   Ohio; Bowling Green State University
RP Beer, KJ (通讯作者)，ProMed Toledo Hosp, Wildwood Orthoped & Spine Inst, Dept Orthoped Surg, 2865 N Reynolds Rd,160, Toledo, OH 43615 USA.
OI Redfern, Roberta/0000-0001-9883-2910
CR Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Bozkurt B, 2015, TRANSPL P, V47, P1515, DOI 10.1016/j.transproceed.2015.04.057
   Burns AWR, 2006, CLIN ORTHOP RELAT R, P29, DOI 10.1097/01.blo.0000214420.14088.76
   Colli A, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-160
   DeCarbo WT, 2010, J FOOT ANKLE SURG, V49, P299, DOI 10.1053/j.jfas.2010.01.002
   Dohmen PM, 2014, GMS HYG INFECT CONTR, V9, DOI 10.3205/dgkh000239
   Galat DD, 2009, J BONE JOINT SURG AM, V91A, P48, DOI 10.2106/JBJS.G.01371
   Gomoll AH, 2006, J ORTHOP TRAUMA, V20, P705, DOI 10.1097/01.bot.0000211159.98239.d2
   Grauhan O, 2014, INT WOUND J, V11, P6, DOI 10.1111/iwj.12294
   Grauhan O, 2013, J THORAC CARDIOV SUR, V145, P1387, DOI 10.1016/j.jtcvs.2012.09.040
   Horch RE, 2015, J WOUND CARE, V24, P21, DOI 10.12968/jowc.2015.24.Sup4b.21
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   Jones Richard E, 2010, Orthopedics, V33, P660, DOI 10.3928/01477447-20100722-35
   Kamolz LP, 2004, BURNS, V30, P253, DOI 10.1016/j.burns.2003.12.003
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Kilpadi DV, 2014, AESTHET PLAST SURG, V38, P767, DOI 10.1007/s00266-014-0339-x
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Koval Kenneth J, 2007, Am J Orthop (Belle Mead NJ), V36, P261
   Kurtz S, 2007, J BONE JOINT SURG AM, V89A, P780, DOI 10.2106/JBJS.F.00222
   Lewis SS, 2015, CLIN INFECT DIS, V60, P990, DOI 10.1093/cid/ciu975
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   Mouës CM, 2007, J PLAST RECONSTR AES, V60, P672, DOI 10.1016/j.bjps.2006.01.041
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Oduwole KO, 2010, KNEE SURG SPORT TR A, V18, P945, DOI 10.1007/s00167-010-1074-8
   Ong KL, 2006, CLIN ORTHOP RELAT R, P22, DOI 10.1097/01.blo.0000214439.95268.59
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Raikin SM, 2010, J BONE JOINT SURG AM, V92A, P2150, DOI 10.2106/JBJS.I.00870
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Stannard JP, 2010, INJURY, V41, P780, DOI 10.1016/j.injury.2009.08.011
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Weir G, 2014, INT WOUND J, V11, P10, DOI 10.1111/iwj.12261
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Zmistowski B, 2011, CLIN ORTHOP RELAT R, V469, P138, DOI 10.1007/s11999-010-1558-3
NR 37
TC 69
Z9 80
U1 0
U2 10
PU CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS
PI PHILADELPHIA
PA CURTIS CENTER, INDEPENDENCE SQUARE WEST, PHILADELPHIA, PA 19106-3399 USA
SN 0883-5403
EI 1532-8406
J9 J ARTHROPLASTY
JI J. Arthroplast.
PD NOV
PY 2017
VL 32
IS 11
BP 3333
EP 3339
DI 10.1016/j.arth.2017.06.019
PG 7
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA FM7DA
UT WOS:000415229700013
PM 28705547
DA 2026-07-24
ER

PT J
AU Brennfleck, FW
   Linsenmeier, L
   Junger, HHG
   Schmidt, KM
   Werner, JM
   Woehl, D
   Zeman, F
   Mutzbauer, I
   Hutchinson, JA
   Geissler, EK
   Schlitt, HJ
   Brunner, SM
AF Brennfleck, Frank W.
   Linsenmeier, Lena
   Junger, Henrik H. G.
   Schmidt, Katharina M.
   Werner, Jens M.
   Woehl, Daniel
   Zeman, Florian
   Mutzbauer, Ingrid
   Hutchinson, James A.
   Geissler, Edward K.
   Schlitt, Hans J.
   Brunner, Stefan M.
TI Negative pressure wound therapy (NPWT) on closed incisions to prevent
   surgical site infection in high-risk patients in hepatopancreatobiliary
   surgery: study protocol for a randomized controlled trial-the NP-SSI
   trial
SO TRIALS
LA English
DT Article
DE NP-SSI; SSI; NPWT; ciNPWT; Incision management; Prevena; Wound
   infection; HPB surgery; Randomized controlled trial
ID COMPLICATIONS; RESECTION; PREVALENCE; RECURRENCE; LAPAROTOMY;
   MANAGEMENT; DRESSINGS; OUTCOMES; IMPACT
AB BackgroundIncisional surgical site infections (iSSI) in hepatopancreatobiliary (HPB) surgery usually lead to prolonged hospital stays, consume valuable resources, and impact on patients' outcome. Prophylactic closed incision negative pressure wound therapy (ciNPWT) to decrease wound complications has become available. Owing to an increasing number of studies, evidence for superiority in many indication areas has accumulated; however, in general surgery, there are a few data and those have shown contradictory results.MethodsIn this monocentric, prospective, randomized, controlled, two-armed study, the influence of ciNPWT on incisional surgical site infection rates after HPB operations will be investigated. A total of 222 patients will be randomized 1:1 to an interventional group (7-day treatment with ciNPWT) or a control group (treated with gauze dressing). The primary parameter to evaluate efficacy is the rate of incisional SSIs within 30days after surgery. Additionally, several clinically relevant secondary outcomes will be assessed.DiscussionA reduction in the rate of incisional SSIs would not only lead to a significant cost reduction and shorter postoperative length of stay, but may also improve postoperative quality of life for patients. While earlier publications have shown advantages for ciNPWT, recent studies did not confirm a positive effect regarding iSSI rate. Even if iSSI rate is not reduced, findings obtained from the secondary endpoints may be of clinical relevance, such as reduction of wound complication rates.Trial registrationThis trial has been registered in the German Clinical Trials Register, DRKS 00015136. Registered on 19 February 2019 and has been approved by the local ethics committee of the University of Regensburg: 18-1225-101.
C1 [Brennfleck, Frank W.; Linsenmeier, Lena; Junger, Henrik H. G.; Schmidt, Katharina M.; Werner, Jens M.; Woehl, Daniel; Mutzbauer, Ingrid; Hutchinson, James A.; Geissler, Edward K.; Schlitt, Hans J.; Brunner, Stefan M.] Univ Hosp Regensburg, Dept Surg, Franz Josef Str Allee 11, D-93053 Regensburg, Germany.
   [Zeman, Florian] Univ Hosp Regensburg, Ctr Clin Trials, Franz Josef Str Allee 11, D-93053 Regensburg, Germany.
C3 University of Regensburg; University of Regensburg
RP Brennfleck, FW (通讯作者)，Univ Hosp Regensburg, Dept Surg, Franz Josef Str Allee 11, D-93053 Regensburg, Germany.
EM frank.brennfleck@klinik.uni-regensburg.de
RI Schlitt, Hans/ABG-4368-2020; Geissler, Edward/R-4131-2016; Hutchinson,
   James/H-3401-2019; Brunner, Stefan/PGF-2582-2026; Brennfleck,
   Frank/GOV-6490-2022; Zeman, Florian/GNH-3239-2022
OI Brennfleck, Frank/0000-0001-8055-9282; Zeman,
   Florian/0000-0002-8425-984X; Werner, Jens/0000-0001-7156-4370
FU KCI Europe Holding B. V (Utrecht, NL)
FX The costs incurred for data management, statistics, monitoring, and the
   administration of the study are partly financed by KCI Europe Holding B.
   V (Utrecht, NL). The company is not involved in these processes and has
   no access to the data. The Prevena dressings and devices are provided
   free of charge by KCI Europe Holding B. V (Utrecht, NL). There is no
   influence or restriction on publications. The study has been initiated,
   planned, and will be managed by the independent authors without conflict
   of interest. The funding company has not been participating in design of
   the study, data collection, interpretation of data, or writing the final
   manuscript. Open Access funding enabled and organized by Projekt DEAL.
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   [Anonymous], 2017, GLOB GUID PREV SURV
   [Anonymous], SURV SURG SIT INF EU
   Bonds AM, 2013, DIS COLON RECTUM, V56, P1403, DOI 10.1097/DCR.0b013e3182a39959
   Buettner S, 2017, J GASTROINTEST SURG, V21, P1813, DOI 10.1007/s11605-017-3571-2
   Centers for Disease Control and Prevention, National and state healthcare-associated infections report
   Chaboyer W, 2014, HEALTHCARE, V2, P417, DOI 10.3390/healthcare2040417
   Chadi SA, 2014, DIS COLON RECTUM, V57, P999, DOI 10.1097/DCR.0000000000000161
   Condé-Green A, 2013, ANN PLAS SURG, V71, P394, DOI 10.1097/SAP.0b013e31824c9073
   Correa-Gallego C, 2013, ANN SURG ONCOL, V20, P2477, DOI 10.1245/s10434-013-2975-9
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   European Centre for Disease Prevention and Control, POINT PREV SURV HEAL
   Friede T, 2004, PHARM STAT, V3, P269, DOI 10.1002/pst.140
   Gassman A, 2015, HERNIA, V19, P273, DOI 10.1007/s10029-014-1312-y
   Gastmeier P, 2008, DEUT MED WOCHENSCHR, V133, P1111, DOI 10.1055/s-2008-1077224
   Gillespie BM, 2015, SURG INNOV, V22, P488, DOI 10.1177/1553350615573583
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Graf K, 2011, LANGENBECK ARCH SURG, V396, P453, DOI 10.1007/s00423-011-0772-0
   Gunatilake RP, 2017, AJP REP, V7, pE151, DOI 10.1055/s-0037-1603956
   Haruki K, 2013, ANTICANCER RES, V33, P1697
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   Hyldig N, 2019, BJOG-INT J OBSTET GY, V126, P628, DOI 10.1111/1471-0528.15413
   Jansen-Winkeln B, 2018, BIOMED RES INT, V2018, DOI 10.1155/2018/7058461
   Javed AA, 2019, ANN SURG, V269, P1034, DOI 10.1097/SLA.0000000000003056
   Leaper David J, 2004, Int Wound J, V1, P247, DOI 10.1111/j.1742-4801.2004.00067.x
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Li PY, 2017, SCAND J SURG, V106, P189, DOI 10.1177/1457496916668681
   Ma ZJ, 2017, INT J MOL MED, V40, P1415, DOI 10.3892/ijmm.2017.3131
   Magill SS, 2014, NEW ENGL J MED, V370, P1198, DOI 10.1056/NEJMoa1306801
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Masden D, 2012, ANN SURG, V255, P1043, DOI 10.1097/SLA.0b013e3182501bae
   Molena D, 2015, J GASTROINTEST SURG, V19, P142, DOI 10.1007/s11605-014-2642-x
   Muenchow S, 2019, CLIN HEMORHEOL MICRO, V72, P365, DOI 10.3233/CH-180536
   Murphy PB, 2019, ANN SURG, V270, P38, DOI 10.1097/SLA.0000000000003111
   Nakahira S, 2013, J HEPATO-BIL-PAN SCI, V20, P504, DOI 10.1007/s00534-012-0590-y
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Pellino G, 2014, INT J SURG, V12, pS64, DOI 10.1016/j.ijsu.2014.08.378
   Pinkney TD, 2013, BMJ-BRIT MED J, V347, DOI 10.1136/bmj.f4305
   Ruhstaller K, 2017, AM J PERINAT, V34, P1125, DOI 10.1055/s-0037-1604161
   Selvaggi Francesco, 2014, Surg Technol Int, V24, P83
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Soares KC, 2015, AM J SURG, V209, P324, DOI 10.1016/j.amjsurg.2014.06.022
   Speicher PJ, 2014, HPB, V16, P1068, DOI 10.1111/hpb.12275
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Wells CI, 2019, WORLD J SURG, V43, P2779, DOI 10.1007/s00268-019-05116-6
   Wihbey KA, 2018, OBSTET GYNECOL, V132, P377, DOI [10.1097/AOG.0000000000002744, 10.1097/aog.0000000000002744]
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
NR 49
TC 5
Z9 6
U1 1
U2 4
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1745-6215
J9 TRIALS
JI Trials
PD NOV 9
PY 2020
VL 21
IS 1
AR 918
DI 10.1186/s13063-020-04831-z
PG 14
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA OU9EZ
UT WOS:000591827600003
PM 33168081
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Stichling, M
   Wiessner, A
   Kikhney, J
   Gatzer, R
   Mueller, M
   Scheuermann-Poley, C
   Moter, A
   Willy, C
AF Stichling, Marcus
   Wiessner, Alexandra
   Kikhney, Judith
   Gatzer, Renate
   Mueller, Martin
   Scheuermann-Poley, Catharina
   Moter, Annette
   Willy, Christian
TI Is There a Wound Recontamination by Eluates with High Bacterial Load in
   Negative-Pressure Wound Therapy with Instillation and Dwell Time?
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID IN-SITU HYBRIDIZATION; TARGETED OLIGONUCLEOTIDE PROBES; IDENTIFICATION;
   INFECTIONS; MANAGEMENT; FOAMS; BIOBURDEN; CONSENSUS; EFFICACY; IMPACT
AB Background:This study investigated bacterial colonization of the foam eluate after negative-pressure wound therapy (NPWT) with instillation and dwell time (NPWTi-d) to obtain an indication of possible recontamination of the wound during NPWTi-d. To detect bacterial colonization and the extent of planktonic and nonplanktonic bioburden as comprehensively as possible, routine culture and molecular biology methods were used. Methods:Before (time point 1) and after (median 3.0 days; time point 2) NPWT (n = 15) and NPWTi-d with antiseptic installation (n = 15), wound bed [22 acute, eight chronic wounds; median age, 51 years (range, 24 to 91); 26 men], foam, and eluate were examined by routine culture methods and fluorescence in situ hybridization (FISH), polymerase chain reaction, and FISH sequencing (FISHseq). Results:At time point 2, 94.9% (37 of 39) of the pathogens identifiable in the eluate were also detected in the wound bed. Foam and eluate were always bacterially contaminated. NPWTi-d resulted in a significant reduction in the number of pathogen species compared with NPWT (NPWTi-d, time point 1 versus time point 2: P = 0.026; NPWT, time point 1 versus time point 2: not significant). Routine culture of wound bed samples at time point 2 identified only 28 of 52 (53.8%) of the pathogens, whereas examination of wound bed, foam, and eluate and additional FISHseq use detected 50 of 52 (96.2%) of the bacterial species. FISHseq identified biofilm in one and microcolonies in 10 wounds (time point 2). Conclusions:The bacterial load of the foam is flushed back into the wound during NPWTi-d. FISHseq should be used in addition to the routine culture method when pathogen identification and detection of nonplanktonic bacterial growth is particularly important for the patient's therapy.
C1 [Stichling, Marcus; Scheuermann-Poley, Catharina; Willy, Christian] Res & Treatment Ctr Sept Defect Wounds, Trauma & Orthoped Surg, Sept & Reconstruct Surg, Berlin, Germany.
   [Wiessner, Alexandra; Kikhney, Judith; Moter, Annette] Charite Univ Med Berlin, Inst Microbiol Infect Dis & Immunol, Biofilmctr, Berlin, Germany.
   [Gatzer, Renate; Mueller, Martin] Bundeswehr Mil Acad Hosp, Fed Armed Forces Germany, Dept Microbiol, Berlin, Germany.
   [Willy, Christian] Mil Acad Hosp, Fed Armed Forces Germany, Res & Treatment Ctr Sept Defect Wounds, Sept & Reconstruct Surg,Trauma & Orthoped Surg, Scharnhorststr 13, D-1310115 Berlin, Germany.
C3 Free University of Berlin; Humboldt University of Berlin; Charite
   Universitatsmedizin Berlin
RP Willy, C (通讯作者)，Mil Acad Hosp, Fed Armed Forces Germany, Res & Treatment Ctr Sept Defect Wounds, Sept & Reconstruct Surg,Trauma & Orthoped Surg, Scharnhorststr 13, D-1310115 Berlin, Germany.
EM christianwilly@bundeswehr.org
RI Kikhney, Judith/HLH-0746-2023; Moter, Annette/IAL-9880-2023
OI Kikhney, Judith/0000-0002-4849-7947; Moter, Annette/0000-0003-1318-5780
FU German Armed Forces as a special research project of the Office of
   Defence Medical Research and Development [SoFo 15K4-S-121517]
FX The authors thank the medical colleagues of the Department of Trauma
   Surgery and Orthopaedics and the surgical assistants of their hospital
   who helped obtain samples from the study participants; Dr. Dennis Vogt
   for contributions and suggestions in the interpretation of the study
   results; Drs. Daniel Koeppen and Nadine Schaefer for support in the
   statistical analysis; and the biofilm center team for technical support
   during fluorescence in situ hybridization sequencing analysis. This
   study was funded by the German Armed Forces as a special research
   project (SoFo 15K4-S-121517) of the Office of Defence Medical Research
   and Development. The funders had no role in study design, data
   collection and analysis, decision to publish, or preparation of the
   manuscript
CR Al-Mayahi M, 2015, J INFECTION, V71, P518, DOI 10.1016/j.jinf.2015.08.002
   AMANN RI, 1990, APPL ENVIRON MICROB, V56, P1919, DOI 10.1128/AEM.56.6.1919-1925.1990
   Anagnostakos K, 2012, J WOUND CARE, V21, P333, DOI 10.12968/jowc.2012.21.7.333
   Apelqvist Jan, 2017, J Wound Care, V26, pS1, DOI [10.12968/jowc.2017.26.sup3.s1, 10.12968/jowc.2017.26.Sup3.S1]
   Aragón-Sánchez J, 2013, INT J LOW EXTR WOUND, V12, P130, DOI 10.1177/1534734613476710
   BAUER AW, 1966, AM J CLIN PATHOL, V45, P493
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   BROSIUS J, 1978, P NATL ACAD SCI USA, V75, P4801, DOI 10.1073/pnas.75.10.4801
   Chowdhry SA, 2019, PRS-GLOB OPEN, V7, DOI 10.1097/GOX.0000000000002087
   Davis K, 2013, WOUND REPAIR REGEN, V21, P869, DOI 10.1111/wrr.12104
   Diehm YF, 2021, PLAST RECONSTR SURG, V147, p43S, DOI 10.1097/PRS.0000000000007610
   Gescher DM, 2008, INT J ANTIMICROB AG, V32, pS51, DOI 10.1016/j.ijantimicag.2008.06.007
   Goss S G, 2012, J Am Coll Clin Wound Spec, V4, P74, DOI 10.1016/j.jccw.2014.02.001
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Hall-Stoodley L, 2012, FEMS IMMUNOL MED MIC, V65, P127, DOI 10.1111/j.1574-695X.2012.00968.x
   Kim PJ, 2020, INT WOUND J, V17, P174, DOI 10.1111/iwj.13254
   Kim PJ, 2014, PLAST RECONSTR SURG, V133, P709, DOI 10.1097/01.prs.0000438060.46290.7a
   Kim PJ, 2013, PLAST RECONSTR SURG, V132, P1569, DOI 10.1097/PRS.0b013e3182a80586
   Kirketerp-Moller K, 2008, J CLIN MICROBIOL, V46, P2717, DOI 10.1128/JCM.00501-08
   Kramer A, 2018, SKIN PHARMACOL PHYS, V31, P28, DOI 10.1159/000481545
   Lalliss SJ, 2010, J ORTHOP TRAUMA, V24, P598, DOI 10.1097/BOT.0b013e3181ec45ba
   Lessing C, 2011, WOUNDS, V23, P309
   Ludolph I, 2018, INT WOUND J, V15, P978, DOI 10.1111/iwj.12958
   Moch D, 1998, Langenbecks Arch Chir Suppl Kongressbd, V115, P1197
   Moter A, 1998, MICROBIOL-SGM, V144, P2459, DOI 10.1099/00221287-144-9-2459
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Omar M, 2016, J WOUND CARE, V25, P475, DOI 10.12968/jowc.2016.25.8.475
   Pawar V, 2015, ANTIMICROB AGENTS CH, V59, P4974, DOI 10.1128/AAC.00194-15
   Qiu Y, 2019, J CRANIO MAXILL SURG, V47, P837, DOI 10.1016/j.jcms.2019.01.031
   Rojas P, 2017, ANAEROBE, V47, P25, DOI 10.1016/j.anaerobe.2017.03.012
   Scherrer AU, 2016, J CLIN MICROBIOL, V54, P2190, DOI 10.1128/JCM.01102-16
   Schoenrath F, 2021, ASAIO J, V67, P536, DOI 10.1097/MAT.0000000000001260
   Tata MD, 2009, ANN THORAC SURG, V87, P1613, DOI 10.1016/j.athoracsur.2008.10.019
   Téot L, 2014, WOUND REPAIR REGEN, V22, P341, DOI 10.1111/wrr.12179
   Timmers MS, 2009, WOUND REPAIR REGEN, V17, P278, DOI 10.1111/j.1524-475X.2009.00458.x
   Trebesius K, 2000, MED MICROBIOL IMMUN, V188, P169, DOI 10.1007/s004300000035
   WALLNER G, 1993, CYTOMETRY, V14, P136, DOI 10.1002/cyto.990140205
   Wolvos Tom A, 2014, Surg Technol Int, V24, P53
   Yang C, 2017, WOUNDS, V29, P240
   Yusuf E, 2013, WOUND REPAIR REGEN, V21, P677, DOI 10.1111/wrr.12088
NR 40
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JAN
PY 2023
VL 151
IS 1
BP E136
EP E147
DI 10.1097/PRS.0000000000009770
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 7K6OP
UT WOS:000905400200030
PM 36251856
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Berner-Hansen, V
   Oma, E
   Willaume, M
   Jensen, KK
AF Berner-Hansen, V.
   Oma, E.
   Willaume, M.
   Jensen, K. K.
TI Prophylactic negative pressure wound therapy after open ventral hernia
   repair: a systematic review and meta-analysis
SO HERNIA
LA English
DT Review
DE iNPWT; Ventral hernia repair; Surgical site occurrences; Surgical site
   infections; Incisional hernia repair; Wound complications
ID ABDOMINAL-WALL RECONSTRUCTION; CLOSED-INCISION; COMPONENT SEPARATION;
   COMPLICATIONS; MANAGEMENT; OUTCOMES; COST
AB Purpose Negative pressure wound therapy on closed incisions (iNPWT) is a wound dressing system developed to promote wound healing and avoid complications after surgical procedures. The effect of iNPWT is well established in various surgical fields, however, the effect on postoperative wound complications after ventral hernia repair remains unknown. The aim of this systematic review and meta-analysis was to investigate the effect of iNPWT on patients undergoing open ventral hernia repair (VHR) compared with conventional wound dressing. Materials and methods This systematic review and meta-analysis followed the PRISMA guidelines. The databases PubMed, Embase, Cochrane Library, Web of science and Cinahl were searched for original studies comparing iNPWT to conventional wound dressing in patients undergoing VHR. The primary outcome was surgical site occurrence (SSO), secondary outcomes included surgical site infection (SSI) and hernia recurrence. Results The literature search identified 373 studies of which 10 were included in the meta-analysis including a total of 1087 patients. Eight studies were retrospective cohort studies, one was a cross-sectional pilot study, and one was a randomized controlled trial. The meta-analysis demonstrated that iNPWT was associated with a decreased risk of SSO (OR 0.27 [0.19, 0.38]; P < 0.001) and SSI (OR 0.32 [0.17, 0.55]; P < 0.001). There was no statistically significant association with the risk of hernia recurrence (OR 0.62 [0.27, 1.43]; P = 0.26). Conclusion Based on the findings of this systematic review and meta-analysis iNPWT following VHR was found to significantly reduce the incidence of SSO and SSI, compared with standard wound dressing. INPWT should be considered for patients undergoing VHR.
C1 [Berner-Hansen, V.; Oma, E.; Willaume, M.; Jensen, K. K.] Bispebjerg Hosp, Ctr Digest Dis, Bispebjerg Bakke 23, DK-2400 Copenhagen NV, Denmark.
C3 University of Copenhagen; Copenhagen University Hospital; Bispebjerg
   Hospital
RP Berner-Hansen, V (通讯作者)，Bispebjerg Hosp, Ctr Digest Dis, Bispebjerg Bakke 23, DK-2400 Copenhagen NV, Denmark.
EM Victoriaberner@hotmail.com
RI Jensen, Kristian/AAI-6028-2020
OI Berner-Hansen, Victoria/0000-0002-7709-6093; Oma,
   Erling/0000-0003-0273-8992; Kiim, Kristian
   Schaumburg/0000-0003-4212-4936
CR [Anonymous], 2012, Surg Infect (Larchmt), V13 Suppl 1, pS9, DOI 10.1089/sur.2012.9908
   [Anonymous], 2020, REV MANAGER REVMAN C
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Breuing K, 2010, SURGERY, V148, P544, DOI 10.1016/j.surg.2010.01.008
   Bueno-Lledó J, 2021, ANN SURG, V273, P1081, DOI 10.1097/SLA.0000000000004310
   Chopra K, 2016, PLAST RECONSTR SURG, V137, P1284, DOI 10.1097/PRS.0000000000002024
   Cobb WS, 2015, J AM COLL SURGEONS, V220, P606, DOI 10.1016/j.jamcollsurg.2014.12.055
   Condé-Green A, 2013, ANN PLAS SURG, V71, P394, DOI 10.1097/SAP.0b013e31824c9073
   Cox TC, 2016, J SURG RES, V206, P214, DOI 10.1016/j.jss.2016.08.009
   de Vries FEE, 2017, HERNIA, V21, P583, DOI 10.1007/s10029-017-1620-0
   Diaconu SC, 2020, HERNIA, V24, P49, DOI 10.1007/s10029-018-1865-2
   Fleischmann W, 1997, UNFALLCHIRURG, V100, P301, DOI 10.1007/s001130050123
   Gassman A, 2015, HERNIA, V19, P273, DOI 10.1007/s10029-014-1312-y
   Görgülü T, 2015, AESTHET SURG J, V35, pNP113, DOI 10.1093/asj/sju120
   Haskins IN, 2018, HERNIA, V22, P729, DOI 10.1007/s10029-018-1748-6
   Hopkins B, 2021, SURG ENDOSC, V35, P3949, DOI 10.1007/s00464-020-07857-1
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Jensen KK, 2020, HERNIA, V24, P265, DOI 10.1007/s10029-019-01978-w
   Jensen KK, 2016, HERNIA, V20, P249, DOI 10.1007/s10029-016-1471-0
   Jensen KK, 2020, SURGERY, V167, P757, DOI 10.1016/j.surg.2019.12.007
   Jensen KK, 2017, ANN SURG, V265, P1235, DOI 10.1097/SLA.0000000000001827
   Jensen KK, 2014, SURG ENDOSC, V28, P3046, DOI 10.1007/s00464-014-3599-2
   Jensen KK, 2019, SURGERY, V165, P393, DOI 10.1016/j.surg.2018.07.035
   Licari L, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.8283
   McGuinness LA, 2021, RES SYNTH METHODS, V12, P55, DOI 10.1002/jrsm.1411
   Moher D, 2009, BMJ-BRIT MED J, V339, DOI 10.1136/bmj.b2535
   Muse TO, 2018, AM SURGEON, V84, P433, DOI 10.1177/000313481808400330
   Nissen AT, 2019, ANN PLAS SURG, V82, pS332, DOI 10.1097/SAP.0000000000001768
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Olona C, 2014, ADV SKIN WOUND CARE, V27, P77, DOI 10.1097/01.ASW.0000442873.48590.b5
   Parker SG, 2020, BJS-BRIT J SURG, V107, P209, DOI 10.1002/bjs.11400
   Pauli EM, 2013, SURG INFECT, V14, P270, DOI 10.1089/sur.2012.059
   Plymale MA, 2017, SURG ENDOSC, V31, P341, DOI 10.1007/s00464-016-4977-8
   Rodriguez-Unda N, 2015, J GASTROINTEST SURG, V19, P2054, DOI 10.1007/s11605-015-2894-0
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Schlosser KA, 2019, PLAST RECONSTR SURG, V143, p15S, DOI 10.1097/PRS.0000000000005307
   Singh D, 2018, PLAST RECONSTR SURG, V142, p156S, DOI 10.1097/PRS.0000000000004872
   Soares KC, 2015, AM J SURG, V209, P324, DOI 10.1016/j.amjsurg.2014.06.022
   Sterne JAC, 2016, BMJ-BRIT MED J, V355, DOI 10.1136/bmj.i4919
   Swanson EW, 2016, PLAST SURG-CHIR PLAS, V24, P113, DOI 10.1177/229255031602400207
   Zwanenburg PR, 2021, WOUND REPAIR REGEN, V29, P8, DOI 10.1111/wrr.12858
NR 42
TC 15
Z9 17
U1 0
U2 4
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1265-4906
EI 1248-9204
J9 HERNIA
JI Hernia
PD DEC
PY 2021
VL 25
IS 6
BP 1481
EP 1490
DI 10.1007/s10029-021-02485-7
EA AUG 2021
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA XC8RX
UT WOS:000684919400002
PM 34392436
DA 2026-07-24
ER

PT J
AU Katzengold, R
   Orlov, A
   Gefen, A
AF Katzengold, Rona
   Orlov, Alexey
   Gefen, Amit
TI A novel system for dynamic stretching of cell cultures reveals the
   mechanobiology for delivering better negative pressure wound therapy
SO BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
LA English
DT Article
DE Chronic and acute wound healing; Scratch wound assay; Cell biomechanics;
   Surgical wounds; Tissue repair
ID MESENCHYMAL STEM-CELLS; CYCLIC STRETCH; IN-VITRO; MIGRATION; FIBROBLAST;
   PROLIFERATION; STIMULATION; KINEMATICS; STRAINS; TENSILE
AB Serious wounds, both chronic and acute (e.g., surgical), are among the most common, expensive and difficult-to-treat health problems. Negative pressure wound therapy (NPWT) is considered a mainstream procedure for treating both wound types. Soft tissue deformation stimuli are the crux of NPWT, enhancing cell proliferation and migration from peri-wound tissues which contributes to healing. We developed a dynamic stretching device (DSD) contained in a miniature incubator for applying controlled deformations to fibroblast wound assays. Prior to the stretching experiments, fibroblasts were seeded in 6-well culture plates with elastic substrata and let to reach confluency. Squashing damage was then induced at the culture centers, and the DSD was activated to deliver stretching regimes that represented common clinical NPWT protocols at two peak strain levels, 0.5% and 3%. Analyses of the normalized maximal migration rate (MMR) data for the collective cell movement revealed that for the 3% strain level, the normalized MMR of cultures subjected to a 0.1 Hz stretch frequency regime was similar to 1.4 times and statistically significantly greater (p < 0.05) than that of the cultures subjected to no-stretch (control) or to static stretch (2nd control). Correspondingly, analysis of the time to gap closure data indicated that the closure time of the wound assays subjected to the 0.1 Hz regime was similar to 30% shorter than that of the cultures subjected to the control regimes (p < 0.05). Other simulated NPWT protocols did not emerge as superior to the controls. The present method and system are a powerful platform for further revealing the mechanobiology of NPWT and for improving this technology.
C1 [Katzengold, Rona; Orlov, Alexey; Gefen, Amit] Tel Aviv Univ, Fac Engn, Dept Biomed Engn, Herbert J Berman Chair Vasc Bioengn, IL-6997801 Tel Aviv, Israel.
C3 Tel Aviv University
RP Gefen, A (通讯作者)，Tel Aviv Univ, Fac Engn, Dept Biomed Engn, Herbert J Berman Chair Vasc Bioengn, IL-6997801 Tel Aviv, Israel.
EM gefen@tauex.tau.ac.il
RI Gefen, Amit/M-4720-2015
OI Gefen, Amit/0000-0002-0223-7218
FU Israel Science Foundation [1266/16]; European Union's Horizon 2020
   research and innovation programme under the Marie Sklodowska-Curie grant
   [811965]
FX We would like to thank Mr. Jelle van Orsouw from Eindhoven University of
   Technology and Dr. Uri Zaretsky from our Department of Biomedical
   Engineering at Tel Aviv University for their help regarding the
   development of the cell stretching apparatus and experimental work. This
   research work was partially supported by the Israel Science Foundation
   Grant No. 1266/16 and by the European Union's Horizon 2020 research and
   innovation programme under the Marie Sklodowska-Curie grant Agreement
   No. 811965.
CR Angelini TE, 2010, PHYS REV LETT, V104, DOI 10.1103/PhysRevLett.104.168104
   Ao M, 2015, SCI REP-UK, V5, DOI 10.1038/srep08334
   Apelqvist Jan, 2017, J Wound Care, V26, pS1, DOI [10.12968/jowc.2017.26.sup3.s1, 10.12968/jowc.2017.26.Sup3.S1]
   Be'ery-Lipperman M, 2005, CLIN BIOMECH, V20, P984, DOI 10.1016/j.clinbiomech.2005.05.018
   Chanet S, 2014, PROG MOL BIOL TRANSL, V126, P317, DOI 10.1016/B978-0-12-394624-9.00013-0
   Chow SE, 2016, BIOMED J, V39, P50, DOI 10.1016/j.bj.2015.08.005
   Dastouri P, 2011, PLAST RECONSTR SURG, V127, P1460, DOI 10.1097/PRS.0b013e31820a63cb
   Desai LP, 2010, J BIOL CHEM, V285, P4511, DOI 10.1074/jbc.M109.084335
   Fronza M, 2009, J ETHNOPHARMACOL, V126, P463, DOI 10.1016/j.jep.2009.09.014
   Geddes DM, 2001, J BIOMECH ENG-T ASME, V123, P247, DOI 10.1115/1.1374201
   Gefen A, 2019, PREVENTION TREATMENT
   Gefen Amit, 2020, J Wound Care, V29, pS1, DOI [10.12968/jowc.2020.29.sup2a.s1, 10.12968/jowc.2020.29.Sup2a.S1]
   Gefen A, 2019, MED ENG PHYS, V72, P13, DOI 10.1016/j.medengphy.2019.08.010
   Ghazanfari S, 2009, BIOCHEM BIOPH RES CO, V388, P601, DOI 10.1016/j.bbrc.2009.08.072
   Hirano Y, 2008, J BIOTECHNOL, V133, P245, DOI 10.1016/j.jbiotec.2007.07.955
   Hong JP, 2013, WOUNDS INT, V4, P6
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Kato T, 1998, BIOCHEM BIOPH RES CO, V244, P615, DOI 10.1006/bbrc.1998.8335
   Katzengold R, 2018, J TISSUE VIABILITY, V27, P101, DOI 10.1016/j.jtv.2017.10.004
   Katzengold R, 2015, BIOMECH MODEL MECHAN, V14, P537, DOI 10.1007/s10237-014-0620-6
   Lalezari S, 2017, INT WOUND J, V14, P649, DOI 10.1111/iwj.12658
   Lee AA, 1996, AM J PHYSIOL-CELL PH, V271, pC1400, DOI 10.1152/ajpcell.1996.271.4.C1400
   Lee KN, 2015, INT WOUND J, V12, P686, DOI 10.1111/iwj.12201
   Leopold E, 2013, MED ENG PHYS, V35, P601, DOI 10.1016/j.medengphy.2012.07.004
   Levy A, 2012, ANN BIOMED ENG, V40, P1052, DOI 10.1007/s10439-011-0496-x
   Liang CC, 2007, NAT PROTOC, V2, P329, DOI 10.1038/nprot.2007.30
   Lin JY, 2019, MATERIALS, V12, DOI 10.3390/ma12172775
   Marom A, 2019, CLIN BIOMECH, V62, P96, DOI 10.1016/j.clinbiomech.2019.01.009
   Monsuur HN, 2016, J BIOMECH, V49, P1381, DOI 10.1016/j.jbiomech.2016.01.040
   Nagai Y, 2012, BIOMATERIALS, V33, P1044, DOI 10.1016/j.biomaterials.2011.10.049
   NARUSE K, 1998, AM J PHYS 2, V274, pH153
   Nussbaum SR, 2018, VALUE HEALTH, V21, P27, DOI 10.1016/j.jval.2017.07.007
   Osada T, 1999, GUT, V45, P508, DOI 10.1136/gut.45.4.508
   Othman Diaa, 2012, Plast Surg Int, V2012, P374398, DOI 10.1155/2012/374398
   Padula WV, 2019, INT WOUND J, V16, P634, DOI 10.1111/iwj.13071
   Paluch EK, 2015, BMC BIOL, V13, DOI 10.1186/s12915-015-0150-4
   Pandit V, 2015, J MECH BEHAV BIOMED, V44, P173, DOI 10.1016/j.jmbbm.2015.01.012
   Pijuan J, 2019, FRONT CELL DEV BIOL, V7, DOI 10.3389/fcell.2019.00107
   Pinto BI, 2019, JOVE-J VIS EXP, DOI 10.3791/58838
   Rajagopalan P, 2004, BIOPHYS J, V87, P2818, DOI 10.1529/biophysj.103.037218
   Rodriguez-Menocal L, 2012, STEM CELL TRANSL MED, V1, P221, DOI 10.5966/sctm.2011-0029
   Shkolyar A, 2015, IEEE ENG MED BIO, P743, DOI 10.1109/EMBC.2015.7318469
   Shoham N, 2012, AM J PHYSIOL-CELL PH, V302, pC429, DOI 10.1152/ajpcell.00167.2011
   Singer AJ, 1999, NEW ENGL J MED, V341, P738, DOI 10.1056/NEJM199909023411006
   Slomka N, 2012, ANN BIOMED ENG, V40, P606, DOI 10.1007/s10439-011-0423-1
   Stroncek J D., 2008, Overview of Wound Healing in Different Tissue Types
   Tai GP, 2018, BURNS TRAUMA, V6, DOI 10.1186/s41038-018-0123-2
   Tokuyama E, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0141989
   Topman G, 2013, MICRON, V51, P9, DOI 10.1016/j.micron.2013.06.002
   Topman G, 2013, J BIOMECH, V46, P170, DOI 10.1016/j.jbiomech.2012.09.015
   Topman G, 2012, ANN BIOMED ENG, V40, P1929, DOI 10.1007/s10439-012-0545-0
   Topman G, 2012, MED ENG PHYS, V34, P225, DOI 10.1016/j.medengphy.2011.07.014
   Topman G, 2011, MICROSC MICROANAL, V17, P915, DOI 10.1017/S1431927611012153
   Toume S, 2017, INT WOUND J, V14, P698, DOI 10.1111/iwj.12679
   Toume S, 2016, J BIOMECH, V49, P1336, DOI 10.1016/j.jbiomech.2016.03.026
   Trepat X, 2012, COMPR PHYSIOL, V2, P2369, DOI [10.1002/j.2040-4603.2012.tb00467.x, 10.1002/cphy.c110012]
   Undyala VV, 2008, J CELL SCI, V121, P3581, DOI 10.1242/jcs.036152
   van Helvert S, 2018, NAT CELL BIOL, V20, P8, DOI 10.1038/s41556-017-0012-0
   Vikatmaa P, 2008, EUR J VASC ENDOVASC, V36, P438, DOI 10.1016/j.ejvs.2008.06.010
   Walter MNM, 2010, EXP CELL RES, V316, P1271, DOI 10.1016/j.yexcr.2010.02.026
   Wiegand C, 2013, WOUND REPAIR REGEN, V21, P793, DOI 10.1111/wrr.12111
   Yadav S, 2017, PAN AFR MED J, V28, DOI 10.11604/pamj.2017.28.246.9606
NR 62
TC 16
Z9 19
U1 1
U2 20
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 1617-7959
EI 1617-7940
J9 BIOMECH MODEL MECHAN
JI Biomech. Model. Mechanobiol.
PD FEB
PY 2021
VL 20
IS 1
BP 193
EP 204
DI 10.1007/s10237-020-01377-6
EA AUG 2020
PG 12
WC Biophysics; Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biophysics; Engineering
GA QJ2PR
UT WOS:000559691100001
PM 32803464
DA 2026-07-24
ER

PT J
AU Kollatos, C
   Sackey, H
   Pantiora, E
   Vorburger, D
   Rocco, N
   Öhrn, C
   Valachis, A
   Eriksson, S
   Karakatsanis, A
AF Kollatos, Christos
   Sackey, Helena
   Pantiora, Eirini
   Vorburger, Denise
   Rocco, Nicola
   Ohrn, Catarina
   Valachis, Antonios
   Eriksson, Staffan
   Karakatsanis, Andreas
TI Clinical and economic impact of incisional negative pressure wound
   therapy in breast surgery: meta-analysis
SO BJS-BRITISH JOURNAL OF SURGERY
LA English
DT Review
ID STANDARD CARE; MASTECTOMY; RISK
AB Background Wound complications after breast surgery are common and contribute to morbidity and healthcare costs. The economic value of prophylactic incisional negative-pressure wound therapy (iNPWT) remains uncertain. This study evaluated the effectiveness and cost-effectiveness of iNPWT in preventing postoperative wound complications (freedom from complication) following breast surgery through a systematic review and meta-analysis.Methods MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched without any restrictions up to 5 March 2025. Randomized trials and prospective or retrospective cohort studies comparing prophylactic iNPWT with standard dressings were included. Two reviewers independently extracted data, assessed risk of bias (RoB 2, ROBINS-I), and graded evidence certainty (GRADE). Random-effects meta-analyses were performed, and cost-effectiveness modelling focused on surgical site infection (SSI).Results Twenty-nine studies including 4904 patients (1817 iNPWT; 3087 controls) were analysed. iNPWT was associated with higher rates of wound dehiscence prevention (RR 1.07, 95% c.i. 1.03 to 1.12), SSI prevention (RR 1.05, 95% c.i. 1.01 to 1.09), and skin necrosis prevention (RR 1.07, 95% c.i. 1.01 to 1.15). No significant differences were observed for seroma, nipple-areolar complex necrosis, or haematoma. Across outcomes, heterogeneity was substantial and 95% prediction intervals crossed the null, indicating uncertainty in the direction of effect in future settings. Evidence certainty ranged from low to moderate. Cost modelling suggested that iNPWT may be cost-saving only in settings with high SSI-related costs.Conclusions Current evidence does not establish consistent clinical benefit of prophylactic iNPWT in breast surgery. Cost-effectiveness appears limited to high-risk or high-cost contexts, supporting selective use.
   Prophylactic iNPWT may confer modest reductions in selected wound complications after breast surgery, but benefits are inconsistent. Cost-effectiveness appears limited to high-risk or high-cost contexts, supporting selective rather than routine use.
C1 [Kollatos, Christos; Pantiora, Eirini; Eriksson, Staffan; Karakatsanis, Andreas] Uppsala Univ, Dept Surg Sci, Akad Sjukhusvagen Ingang 70, S-75185 Uppsala, Sweden.
   [Kollatos, Christos; Pantiora, Eirini; Karakatsanis, Andreas] Uppsala Univ Hosp, Dept Surg, Sect Breast Surg, Uppsala, Sweden.
   [Sackey, Helena] Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden.
   [Sackey, Helena] Karolinska Univ Hosp, Karolinska Comprehens Canc Ctr, Dept Breast Endocrine Tumors & Sarcoma, Stockholm, Sweden.
   [Pantiora, Eirini] Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden.
   [Vorburger, Denise] Cantonal Hosp Winterthur, Breast Unit, Winterthur, Switzerland.
   [Rocco, Nicola] Univ Naples Federico II, Dept Adv Biomed Sci, Naples, Italy.
   [Ohrn, Catarina] Linkoping Univ, Dept Biomed & Clin Sci, Linkoping, Sweden.
   [Ohrn, Catarina] Linkoping Univ Hosp, Dept Surg, Linkoping, Sweden.
   [Valachis, Antonios] Orebro Univ, Fac Med & Hlth, Dept Oncol, Orebro, Sweden.
   [Eriksson, Staffan] Uppsala Univ, Ctr Clin Res Vastmanland, Vasteras, Sweden.
   [Eriksson, Staffan] Vastmanlands Cty Hosp, Dept Surg, Sect Breast Surg, Vasteras, Sweden.
C3 Uppsala University; Uppsala University; Uppsala University Hospital;
   Karolinska Institutet; Karolinska Institutet; Karolinska University
   Hospital; Karolinska Institutet; University of Naples Federico II;
   Linkoping University; Linkoping University; Orebro University; Uppsala
   University; Vasteras Central Hospital
RP Kollatos, C (通讯作者)，Uppsala Univ, Dept Surg Sci, Akad Sjukhusvagen Ingang 70, S-75185 Uppsala, Sweden.
EM christos.kollatos@uu.se
RI Sackey, Helena/KJU-4264-2024
FU Karolinska Institutet; Erik och Majje Nsstrm
FX Helena Sackey was funded through the Erik och Majje Nasstrom donation to
   Karolinska Institutet.
CR Adwall L, 2024, BJS OPEN, V8, DOI 10.1093/bjsopen/zrae137
   Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
   Akhter HM, 2023, PRS-GLOB OPEN, V11, DOI 10.1097/GOX.0000000000005130
   Al-Ishaq Z, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.38167
   Alameddine K., 2023, AESTHET SURG J OPEN, V5
   Alameddine KO, 2024, AESTHET SURG J OPEN, V6, DOI 10.1093/asjof/ojae073
   Borenstein M, 2017, RES SYNTH METHODS, V8, P5, DOI 10.1002/jrsm.1230
   Borenstein M, 2010, RES SYNTH METHODS, V1, P97, DOI 10.1002/jrsm.12
   Cagney D, 2020, WORLD J SURG, V44, P1526, DOI 10.1007/s00268-019-05335-x
   Casella D, 2023, MEDICINA-LITHUANIA, V59, DOI 10.3390/medicina59101703
   Chavez-MacGregor M, 2016, JAMA ONCOL, V2, P322, DOI 10.1001/jamaoncol.2015.3856
   De Rooij L, 2021, SCI REP-UK, V11, DOI 10.1038/s41598-021-89036-3
   De Rooij L, 2021, EJSO-EUR J SURG ONC, V47, P757, DOI 10.1016/j.ejso.2020.10.010
   Diaz R., 2024, EUR J SURG ONCOL, V50
   Dinapoli L, 2021, CURR ONCOL REP, V23, DOI 10.1007/s11912-021-01049-3
   Esen E, 2025, ASIAN J SURG, V48, P185, DOI 10.1016/j.asjsur.2024.07.333
   Fernandes U, 2021, EJSO-EUR J SURG ONC, V47, pe45, DOI 10.1016/j.ejso.2020.11.261
   Ferrando PM, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001732
   Fogacci T, 2020, BREAST J, V26, P1071, DOI 10.1111/tbj.13659
   Gabriel A, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001880
   Galiano RD, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001560
   Groenen H, 2023, ECLINICALMEDICINE, V62, DOI 10.1016/j.eclinm.2023.102105
   Gupta N, 2020, J CLIN EXP HEPATOL, V10, P177, DOI 10.1016/j.jceh.2019.11.001
   Gupta S, 2016, CLIN ONCOL-UK, V28, P739, DOI 10.1016/j.clon.2016.07.010
   Guyatt GH, 2008, BMJ-BRIT MED J, V336, P924, DOI 10.1136/bmj.39489.470347.AD
   Hawa AAA, 2022, PRS-GLOB OPEN, V10, DOI 10.1097/GOX.0000000000004096
   Holt R, 2015, EJSO-EUR J SURG ONC, V41, pS63, DOI 10.1016/j.ejso.2015.03.169
   Hu B, 2006, STAT SINICA, V16, P847
   IntHout J, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2015-010247
   Irwin GW, 2020, PRS-GLOB OPEN, V8, DOI 10.1097/GOX.0000000000002667
   Johnson ON, 2021, PRS-GLOB OPEN, V9, DOI 10.1097/GOX.0000000000003496
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P601, DOI 10.1097/PRS.0b013e318196b97b
   Kim DY, 2016, PLAST RECONSTR SURG, V138, P558, DOI 10.1097/PRS.0000000000002431
   Lane A, 2018, J AM COLL SURGEONS, V227, pS184, DOI 10.1016/j.jamcollsurg.2018.07.393
   Lauritzen E, 2024, EUR J PLAST SURG, V47, DOI 10.1007/s00238-024-02223-z
   Liew AN, 2022, CUREUS J MED SCIENCE, V14, DOI 10.7759/cureus.24499
   McKenzie JE, 2024, COCHRANE HDB SYSTEMA, P33
   Molska M, 2025, CANCERS, V17, DOI 10.3390/cancers17010003
   Murad MH, 2023, BMJ-BRIT MED J, V381, DOI 10.1136/bmj-2022-073141
   Nilsson M, 2024, British Journal of Healthcare Management, V30, P1, DOI 10.12968/bjhc.2023.0118
   Nip L, 2020, EJSO-EUR J SURG ONC, V46, pe34, DOI 10.1016/j.ejso.2020.03.130
   Nyaga VN, 2014, ARCH PUBLIC HEALTH, V72, DOI 10.1186/2049-3258-72-39
   Ockerman KM, 2023, PRS-GLOB OPEN, V11, DOI 10.1097/GOX.0000000000005028
   Olsen MA, 2008, ARCH SURG-CHICAGO, V143, P53, DOI 10.1001/archsurg.2007.11
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Ouzzani M, 2016, SYST REV-LONDON, V5, DOI 10.1186/s13643-016-0384-4
   Page Matthew J, 2021, Int J Surg, V88, P105906, DOI [10.1016/j.rec.2021.07.010, 10.1016/j.ijsu.2021.105906]
   Pellino G, 2014, INT J SURG, V12, pS64, DOI 10.1016/j.ijsu.2014.08.378
   Pieri A, 2023, EJSO-EUR J SURG ONC, V49, pe94, DOI 10.1016/j.ejso.2022.11.287
   Pieszko K, 2023, PLAST RECONSTR SURG, V151, P1123, DOI 10.1097/PRS.0000000000010110
   Ryu JY, 2022, AESTHET PLAST SURG, V46, P633, DOI 10.1007/s00266-020-02115-0
   Sterne J.A. C., 2019, BMJ-BRIT MED J, V366, pl4898, DOI [DOI 10.1136/BMJ.L4898, 10.1136/bmj.l4898]
   Sterne JAC, 2016, BMJ-BRIT MED J, V355, DOI 10.1136/bmj.i4919
   Thalji SZ, 2023, SURG CLIN N AM, V103, P121, DOI 10.1016/j.suc.2022.08.007
   Timmermans FW, 2021, BJS-BRIT J SURG, V108, P925, DOI 10.1093/bjs/znab204
   Tormey S, 2019, EJSO-EUR J SURG ONC, V45, P917, DOI 10.1016/j.ejso.2019.01.146
   Vikatmaa P, 2008, EUR J VASC ENDOVASC, V36, P438, DOI 10.1016/j.ejvs.2008.06.010
   Wareham CM, 2023, PRS-GLOB OPEN, V11, DOI 10.1097/GOX.0000000000004936
   Weber F, 2021, RES SYNTH METHODS, V12, P291, DOI 10.1002/jrsm.1471
NR 59
TC 0
Z9 0
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0007-1323
EI 1365-2168
J9 BJS-BRIT J SURG
JI BJS-Brit. J. Surg.
PD JUN
PY 2026
VL 113
IS 6
AR znag056
DI 10.1093/bjs/znag056
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA JD1RS
UT WOS:001786509500001
PM 42084358
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Zhao, Y
   Dai, XH
   Sun, Y
   Liao, WX
   Peng, Y
   Yang, JY
AF Zhao, Yang
   Dai, Xiaohong
   Sun, Yan
   Liao, Weixiang
   Peng, Yan
   Yang, Jiuyi
TI 被撤回的出版物: Efficacy and Clinical Value of Negative-Pressure Wound Therapy
   with Instillation (NPWTi) of Compound Phellodendron Liquid in the
   Treatment of Diabetic Foot Ulcer: A Prospective Cohort Study (Retracted
   Article)
SO COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
LA English
DT Article; Retracted Publication
AB Objective. To evaluate the efficacy and application value of compound Phellodendron liquid (CPL) for negative-pressure wound therapy with instillation (NPWTi) in the treatment of diabetic foot ulcers by observing the improvement of diabetic foot ulcers. Methods. Sixty patients with diabetic foot ulcers who met the inclusion criteria were admitted to the Department of Peripheral Blood Vessels (Wound Repair) of Chongqing Hospital of Traditional Chinese Medicine from August 2020 to August 2021. The random number table method divided it into the CPL NPWTi group and normal saline NPWTi group, with 30 cases in each group. The experimental group adopted FufangHuangbaiye for NPWTi, and the control group used normal saline for NPWTi. The treatment effect was evaluated by baseline index, wound healing observation index, inflammatory factor index, pain scores during dressing change, and the number of days in hospital. Results. After 10 days of treatment, the symptom integration, procalcitonin (PCT), and C reactive protein (CRP) of the CPL NPWTi group were significantly reduced compared with the normal saline NPWTi group, while there was no obvious difference between wound area and erythrocyte sedimentation rate (ESR). The wound area, symptom integral, PCT, ESR, and CRP of the CPL NPWTi group were significantly reduced compared with the normal saline NPWTi group after treatment for 20 days and 30 days. The positive proportion of bacterial culture in the CPL NPWTi group was significantly reduced compared with the normal saline NPWTi group after treatment for 10 days, 20 days, and 30 days. After treatment, the pain scores during dressing change and the number of days in hospital in normal saline NPWTi group were significantly lower than those in the CPL NPWTi group. Conclusion. Compound Phellodendron liquid NPWTi therapy can improve diabetic foot ulcers, providing a safe and effective method for treating diabetic foot ulcers.
C1 [Zhao, Yang; Sun, Yan; Liao, Weixiang; Yang, Jiuyi] Chongqing Tradit Chinese Med Hosp, Dept Peripheral Vasc Wound Repair, Chongqing 400021, Peoples R China.
   [Dai, Xiaohong; Peng, Yan] Chongqing Tradit Chinese Med Hosp, Dept Urol, Chongqing 400021, Peoples R China.
RP Yang, JY (通讯作者)，Chongqing Tradit Chinese Med Hosp, Dept Peripheral Vasc Wound Repair, Chongqing 400021, Peoples R China.; Peng, Y (通讯作者)，Chongqing Tradit Chinese Med Hosp, Dept Urol, Chongqing 400021, Peoples R China.
EM zhaoyang20160430@163.com; qq973246058@163.com; sy15123482595@163.com;
   lwx114267@163.com; 631406010109@mails.cqjtu.edu.cn;
   yangjiuyi2022@163.com
FU Chengdu University of Traditional Chinese Medicine [YYZX2020053]
FX This study was funded by Chengdu University of Traditional Chinese
   Medicine 2020 "Xinglin scholar" hospital special project (no.
   YYZX2020053).
CR [Anonymous], 2004, WOUNDS, p3S
   Boulton AJM, 2005, LANCET, V366, P1719, DOI 10.1016/S0140-6736(05)67698-2
   Boulton AJM, 2004, DIABETOLOGIA, V47, P1343, DOI 10.1007/s00125-004-1463-y
   Du L.N, 2002, J ARMED POLICE MEDIC, V12, P2
   Dubsky M, 2013, INT WOUND J, V10, P555, DOI 10.1111/j.1742-481X.2012.01022.x
   Frykberg Robert G, 2006, J Foot Ankle Surg, V45, pS1
   [付小兵 Fu Xiaobing], 2005, [中国实用外科杂志, Chinese Journal of Practical Surgery], V25, P29
   Goss S G, 2012, J Am Coll Clin Wound Spec, V4, P74, DOI 10.1016/j.jccw.2014.02.001
   Ju S., 2016, BEIJING TRADITIONAL, V35, P931
   Kim PJ, 2015, Wounds, V27, pS2
   Larsson J, 1998, CLIN ORTHOP RELAT R, P149
   Leow Kimberley, 2020, Wounds, V32, pE120
   [李友山 Li Youshan], 2016, [中国新药杂志, Chinese Journal New Drugs], V25, P2344
   Lin AH, 2019, J CHROMATOGR B, V1122, P18, DOI 10.1016/j.jchromb.2019.05.019
   Ministry of Health of the Peoples Republic of China, 1997, GUID PRINC CLIN STUD
   Moura LIF, 2013, ACTA BIOMATER, V9, P7093, DOI 10.1016/j.actbio.2013.03.033
   Wang C., 2013, DRUG EVALUATION, V10, P45
   Xu XQ, 2021, COLLOID SURFACE B, V199, DOI 10.1016/j.colsurfb.2021.111557
   Yan C.C, 2018, EFFECT COMBINED CORK
   Zhang JJ, 2020, OXID MED CELL LONGEV, V2020, DOI 10.1155/2020/4951820
   Zucchi P, 2005, G Ital Nefrol, V22 Suppl 31, pS20
NR 21
TC 6
Z9 6
U1 0
U2 21
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1748-670X
EI 1748-6718
J9 COMPUT MATH METHOD M
JI Comput. Math. Method Med.
PD AUG 9
PY 2022
VL 2022
AR 7540020
DI 10.1155/2022/7540020
PG 8
WC Mathematical & Computational Biology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Mathematical & Computational Biology
GA 3X9PB
UT WOS:000843363400002
PM 35983532
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Gibson, DJ
AF Gibson, Daniel J.
TI A Comparison of the Biomechanical Performance of 3 Negative Pressure
   Wound Therapy Foams
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE NPWT; NPWT design; NPWT dressings; NPWT testing
ID TISSUE
AB PURPOSE: The purpose of this study was to compare 3 foam dressings to (1) determine the biomechanical performance of existing negative pressure wound therapy (NPWT) foams and (2) to determine if a test foam is possibly suitable as an antimicrobial "white" foam alternative for use in NPWT. DESIGN: A comparison of mechanical performance of 3 foams used for vacuum-assisted NPWT. SUBJECTS AND SETTING: Preclinical laboratory study using an in vitro model. METHODS: The performance of a "white" foam (polyvinyl alcohol [PVA]), an antimicrobial "black" foam (polyurethane [PU]), and an antimicrobial white foam alternative (test PVA) were tested and compared using 3 mechanically relevant criteria. First, the fluid removal rate was measured for 72 hours. Next, the pressure input was compared to the pressure directly beneath the center of the foam. Finally, the spread of negative pressure beneath the foam was measured and compared. RESULTS: Significant differences were found in fluid removal rates; specifically, the PU foam removed fluids faster than the PVA and test PVA foams, and the currently available PVA foams performed similarly. Both the PU and test PVA foams were able to transmit the negative pressure through the center of the dressing, while the typical PVA foam began failing at 140 mm Hg, with 50% of the samples failing at 200 mm Hg. All PU replicate foams evenly distributed the pressure, while 47% to 60% of the test PVA foams and 7% of the typical PVA foams distributed pressures evenly. CONCLUSIONS: Study findings suggest that the test PVA foam does not mechanically interfere with NPWT and performs equivalently to currently used foams. These results suggest that the test PVA may be modified and incorporated into a vacuum-assisted NPWT device. In addition, the methods employed in these experiments provide a reproducible means to compare biomechanical compatibility of various NPWT foams, dressings, and subdrape devices.
C1 [Gibson, Daniel J.] Univ Alabama, Capstone Coll Nursing, 650 Univ Blvd E, Tuscaloosa, AL 35401 USA.
C3 University of Alabama System; University of Alabama Tuscaloosa
RP Gibson, DJ (通讯作者)，Univ Alabama, Capstone Coll Nursing, 650 Univ Blvd E, Tuscaloosa, AL 35401 USA.
EM dgibson1@ua.edu
RI Gibson, Daniel/LRC-9423-2024
FU Hollister Inc
FX The author conducted this research via a contract with Hollister Inc,
   which distributed one of the products subject herein. The product's
   manufacturer, Hydrofera, LLC, sponsored Dr Gibson's effort for
   composition and costs of publication. The sponsors chose the pressure
   distribution pattern beneath the dressing that they would like to be
   measured and manufactured the pressure table and supports. They did not
   have a role in the design of the measurement routine, conduct of the
   research, or data analysis. The sponsors did not write the manuscript
   but were allowed to review it for accuracy pertaining to comments made
   about the sponsors or their intents.
CR Anesäter E, 2012, WOUND REPAIR REGEN, V20, P611, DOI 10.1111/j.1524-475X.2012.00801.x
   Arnold-Long M, 2010, J WOUND OSTOMY CONT, V37, P549, DOI 10.1097/WON.0b013e3181eda751
   Cristescu Ioan, 2017, Key Engineering Materials, V745, P91, DOI [10.4028/www.scientific.net/kem.745.91, 10.4028/www.scientific.net/KEM.745.91]
   Crumley C, 2021, J WOUND OSTOMY CONT, V48, P195, DOI 10.1097/WON.0000000000000761
   de Haas LEM, 2019, J CRANIOFAC SURG, V30, P888, DOI 10.1097/SCS.0000000000005375
   Kane BJ, 2010, J BIOMED MATER RES A, V95A, P333, DOI 10.1002/jbm.a.32840
   Malmsjo Malin, 2014, Eplasty, V14, pe3
   Malmsjö M, 2009, WOUND REPAIR REGEN, V17, P200, DOI 10.1111/j.1524-475X.2009.00461.x
   Menn ZK, 2012, J RECONSTR MICROSURG, V28, P139, DOI 10.1055/s-0031-1289167
   Miller Christine, 2012, J Am Coll Clin Wound Spec, V4, P61, DOI 10.1016/j.jccw.2013.11.002
   Nuutila K, 2019, WOUND REPAIR REGEN, V27, P162, DOI 10.1111/wrr.3
   Peterson DJ, 2005, EFFECTIVELY MANAGING
   Regner Justin L, 2018, Proc (Bayl Univ Med Cent), V31, P25, DOI [10.1080/08998280.2017.1400312, 10.1080/08998280.2017.1400312]
   Shankaran V, 2013, DERMATOL THER, V26, P215, DOI 10.1111/dth.12050
   Smith APS., 2018, CHRONIC WOUND CARE E, P195
   Trengove Naomi J., 1996, Wound Repair and Regeneration, V4, P234, DOI 10.1046/j.1524-475X.1996.40211.x
   Webb M, 2009, J WOUND OSTOMY CONT, V36, pS18
   Wiegand C., 2014, Wound Medicine, V6, P22
NR 18
TC 5
Z9 5
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JAN-FEB
PY 2022
VL 49
IS 1
BP 51
EP 58
DI 10.1097/WON.0000000000000833
PG 8
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA YI1HQ
UT WOS:000743607500009
PM 34855716
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Neron, M
   Delmond, L
   Gourgou, S
   Delaine, S
   Chalbos, P
   Moussion, A
   Taoum, C
AF Neron, Mathias
   Delmond, Laure
   Gourgou, Sophie
   Delaine, Stephanie
   Chalbos, Patrick
   Moussion, Aurore
   Taoum, Christophe
TI Prevention of postoperative complications with negative pressure wound
   therapy after complex breast cancer surgery: a study protocol of a
   randomised controlled trial (TPN-SEIN)
SO BMJ OPEN
LA English
DT Article
DE ONCOLOGY; Breast surgery; WOUND MANAGEMENT; Clinical Protocols
ID SURGICAL OUTCOMES; MASTECTOMY; RECONSTRUCTION; TRENDS; CHEMOTHERAPY;
   IMPACT; LIFE
AB Background Complex breast surgery, including immediate breast reconstruction and oncoplastic procedures, is increasingly performed to optimise oncologic and aesthetic outcomes. Postoperative wound healing complications remain a major concern, particularly in high-risk patients. Negative pressure wound therapy (NPWT) has been shown to improve wound healing in various surgical fields. However, its effectiveness in oncologic breast surgery remains insufficiently studied. This study aims to evaluate the efficacy of NPWT in reducing wound healing complications in complex breast cancer surgery.Methods The TPN-SEIN study is a prospective, randomised, controlled, open-label, multicentre, phase III clinical trial. A total of 254 patients undergoing complex breast cancer surgery will be randomised either to arm 1 (NPWT immediately postoperatively for 7 days) or arm 2 (standard wound care). The primary endpoint is the rate of wound healing complications at day 30, defined as at least one of the following: deep postoperative infection of the prosthetic pocket, wound dehiscence or incomplete healing. Secondary endpoints include surgical site infection at day 90, reoperation rate, hospital readmission rate, time to complete healing, time to adjuvant treatment initiation, quality of life (European Organisation for Research and Treatment of Cancer Core Quality of Life questionnaire and breast cancer-specific quality of life questionnaire (QLQ-C30)), patient satisfaction and medico-economic outcomes.Ethics and dissemination The study was approved by the French national ethics committee (Comit & eacute; de Protection des Personnes Est II, 5 December 2024, reference 24.04416.000295) and the institutional review board (IRB-COMERE, reference ICM-RCM 2024/11). The French National Agency for the Safety of Health Products has been notified. The study results will be presented at both national and international conferences and will also be published in a peer-reviewed journal.Trial registration number NCT06265558.
C1 [Neron, Mathias; Delmond, Laure; Taoum, Christophe] Montpellier Canc Inst, Dept Surg Oncol, Montpellier, France.
   [Neron, Mathias] Montpellier Canc Res Inst, INSERM, U1194, Montpellier, France.
   [Neron, Mathias; Delmond, Laure; Gourgou, Sophie; Delaine, Stephanie; Chalbos, Patrick; Moussion, Aurore; Taoum, Christophe] Univ Montpellier, Montpellier, France.
   [Gourgou, Sophie] Montpellier Canc Inst, Biometr Unit, Montpellier, France.
   [Delaine, Stephanie; Chalbos, Patrick; Moussion, Aurore] Montpellier Canc Inst, Clin Res & Innovat Dept, Montpellier, France.
C3 Universite de Montpellier; UNICANCER; Universite de Montpellier;
   Institut Regional du Cancer Montpellier / Val d'Aurelle (ICM); Institut
   National de la Sante et de la Recherche Medicale (Inserm); Universite de
   Montpellier; Universite de Montpellier; Universite de Montpellier
RP Taoum, C (通讯作者)，Montpellier Canc Inst, Dept Surg Oncol, Montpellier, France.; Taoum, C (通讯作者)，Univ Montpellier, Montpellier, France.
EM Mathias.Neron@icm.unicancer.fr; Laure.Delmond@icm.unicancer.fr;
   Sophie.Gourgou@icm.unicancer.fr; Stephanie.Delaine@icm.unicancer.fr;
   Patrick.Chalbos@icm.unicancer.fr; Aurore.Moussion@icm.unicancer.fr;
   christophe.taoum@icm.unicancer.fr
OI TAOUM, Christophe/0000-0002-7401-331X
FU French Ministry of Health's Directorate General for Healthcare Provision
   [PHRCi-2022-87]
FX This research was funded by the French Ministry of Health's Directorate
   General for Healthcare Provision (DGOS) through the 2022 Interregional
   Hospital Clinical Research Program (PHRCi 2022), under grant number
   PHRCi-2022-87.
CR Andersen IS, 2024, AM J SURG, V237, DOI 10.1016/j.amjsurg.2024.115895
   Bleicher RJ, 2022, ANN SURG ONCOL, V29, P469, DOI 10.1245/s10434-021-10512-1
   Bowen ME, 2017, ANN SURG, V265, P448, DOI 10.1097/SLA.0000000000001804
   Burstein HJ, 2021, ANN ONCOL, V32, P1216, DOI 10.1016/j.annonc.2021.06.023
   Cagney D, 2020, WORLD J SURG, V44, P1526, DOI 10.1007/s00268-019-05335-x
   Chicco M, 2021, ANN PLAS SURG, V87, P478, DOI 10.1097/SAP.0000000000002722
   Ching AH, 2022, J PLAST RECONSTR AES, V75, P2550, DOI 10.1016/j.bjps.2022.02.019
   Clough KB, 2010, ANN SURG ONCOL, V17, P1375, DOI 10.1245/s10434-009-0792-y
   Dauplat J, 2017, BRIT J SURG, V104, P1197, DOI 10.1002/bjs.10537
   Donovan CA, 2016, ANN SURG ONCOL, V23, P3226, DOI 10.1245/s10434-016-5323-z
   Gabriel A, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001880
   Gagliato DD, 2014, J CLIN ONCOL, V32, P735, DOI 10.1200/JCO.2013.49.7693
   Galiano RD, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001560
   Gilmour A, 2021, EJSO-EUR J SURG ONC, V47, P2272, DOI 10.1016/j.ejso.2021.05.006
   Houvenaeghel G, 2024, CANCERS, V16, DOI 10.3390/cancers16061129
   Houvenaeghel Gilles, 2022, J Surg Res (Houst), V5, P500, DOI [10.26502/jsr.10020250, 10.26502/jsr.10020250]
   Huttunen T, 2022, BJS OPEN, V6, DOI 10.1093/bjsopen/zrac096
   Janssen F, 2021, INT J EPIDEMIOL, V50, P931, DOI 10.1093/ije/dyaa273
   Jeevan R, 2016, BRIT J SURG, V103, P1147, DOI 10.1002/bjs.10161
   Johnson ON, 2021, PRS-GLOB OPEN, V9, DOI 10.1097/GOX.0000000000003496
   Kelly BN, 2022, ANN SURG ONCOL, V29, P1033, DOI 10.1245/s10434-021-10767-8
   Nègre G, 2020, ANN CHIR PLAST ESTH, V65, P36, DOI 10.1016/j.anplas.2019.07.014
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Pak LM, 2023, ANN SURG ONCOL, V30, P7091, DOI 10.1245/s10434-023-13962-x
   Panchal H, 2017, PLAST RECONSTR SURG, V140, p7S, DOI 10.1097/PRS.0000000000003941
   Potter S, 2019, LANCET ONCOL, V20, P254, DOI 10.1016/S1470-2045(18)30781-2
   Quilichini O, 2021, ANN MED SURG, V61, P172, DOI 10.1016/j.amsu.2020.12.033
   Rippon MG, 2024, J WOUND CARE, V33
   Rosenberg SM, 2020, JAMA SURG, V155, P1035, DOI 10.1001/jamasurg.2020.3325
   Rousset-Jablonski C, 2024, BREAST CANCER-TOKYO, V31, P633, DOI 10.1007/s12282-024-01576-4
   Saunders C, 2021, BJS OPEN, V5, DOI 10.1093/bjsopen/zraa003
   Tanaydin V, 2018, AESTHET PLAST SURG, V42, P927, DOI 10.1007/s00266-018-1095-0
   Wilkins EG, 2018, ANN SURG, V267, P164, DOI 10.1097/SLA.0000000000002033
   Witmer TJK, 2022, J PLAST RECONSTR AES, V75, P2569, DOI 10.1016/j.bjps.2022.02.050
   Woo SH, 2023, J PLAST SURG HAND SU, V57, P370, DOI 10.1080/2000656X.2022.2118757
NR 35
TC 0
Z9 1
U1 4
U2 4
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 2044-6055
J9 BMJ OPEN
JI BMJ Open
PD JAN 2
PY 2026
VL 16
IS 1
AR e103827
DI 10.1136/bmjopen-2025-103827
PG 8
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA AP6CQ
UT WOS:001653737800001
PM 41485781
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU de Souza, GMC
   Amorim, CCB
   Vallejo, CEA
   Sternick, MB
   da Costa, SM
   Sobral, CS
   Ferreirav, LM
AF Costa de Souza, Gustavo Moreira
   Bizzotto Amorim, Camila Camargos
   Astudillo Vallejo, Cristian Esteban
   Sternick, Marcelo Back
   da Costa, Sergio Moreira
   Sobral, Christiane Steponavicius
   Ferreirav, Lydia Masako
TI Fat grafting associated with negative pressure wound therapy
SO ACTA CIRURGICA BRASILEIRA
LA English
DT Article
DE Negative-Pressure Wound Therapy; Wound Healing; Transplantation;
   Autologous; Biocompatible Materials
AB Purpose: To describe a case report of FG associated with NPWT in the treatment of complex wound on the distal third of the lower limb with bone exposure.
   Case Report: A 59-year-old patient with chronic left tibial osteomyelitis since childhood underwent extensive debridement of the distal tibial diaphysis (40% of bone thickness per 10 cm extension) and placement of bioactive glass S53P4. Distal necrosis occurred in the fasciocutaneous flap used as the primary bone coverage. After flap debridement, the case was resolved with FG, directly on the exposed bone and biomaterial, associated with NPWT. Three weeks after the first FG session over bony tissue, 100% granulation was achieved with NPWT. The closure was completed with thin laminated skin graft over the granulated wound area.
   Discussion: The association of FG and NPWT is not known in the clinical practice. Except for the only one experimental study described by Kao et a', the theme was not addressed in the medical literature before. In this clinical case, the result obtained regarding the granulation tissue formation drew attention and prevented the use of more complex flaps such as the microsurgical ones. Accelerated granulation tissue formation was observed, filling an extensive and deep bone defect, even with infected bone and biomaterial. Low morbidity and no complications were observed with the use of FG associated with NPWT. When the grafted fat was compacted with the NPWT, it seemed to behave as a true autologous biological matrix with large amount of cells. To date, scientific studies on fat grafting have focused on the cellular aspect (adipocytes and mesenchymal cells), growth factors and fat differentiation in different tissues. The property of aspirated adipose tissue as a biological matrix seemed to be revealed by the application of NPWT in association with FG. This new roll for the aspirated fat tissue may represent a new research field in plastic surgery.
C1 [Costa de Souza, Gustavo Moreira] Univ Fed Sao Paulo UNIFESP, Postgrad Program Translat Surg, Div Plast Surg, Dept Surg, Sao Paulo, SP, Brazil.
   [Bizzotto Amorim, Camila Camargos; Astudillo Vallejo, Cristian Esteban] Hosp Felicio Rocho, Plast Surg & Burn Clin, Postgrad Program Plast Surg, Surg, Belo Horizonte, MG, Brazil.
   [Sternick, Marcelo Back] Hosp Felicio Rocho, Orthopaed Surg Div, Belo Horizonte, MG, Brazil.
   [da Costa, Sergio Moreira] Hosp Felicio Rocho, Div Plast Surg, Belo Horizonte, MG, Brazil.
   [Sobral, Christiane Steponavicius] Hosp Defeitos Face Cruz Vermelha Brasileira, Div Plast Surg, Sao Paulo, SP, Brazil.
   [Ferreirav, Lydia Masako] Univ Fed Sao Paulo, Div Plast Surg, Sao Paulo, SP, Brazil.
   [Ferreirav, Lydia Masako] CNPq, Sao Paulo, SP, Brazil.
   [Ferreirav, Lydia Masako] CAPES, Med 3, Sao Paulo, SP, Brazil.
   [Costa de Souza, Gustavo Moreira; Bizzotto Amorim, Camila Camargos; Astudillo Vallejo, Cristian Esteban; Sternick, Marcelo Back; da Costa, Sergio Moreira; Sobral, Christiane Steponavicius; Ferreirav, Lydia Masako] Hosp Felicio Rocho, Plast Surg & Burn Clin, Belo Horizonte, MG, Brazil.
C3 Universidade Federal de Sao Paulo (UNIFESP); Universidade Federal de Sao
   Paulo (UNIFESP); Coordenacao de Aperfeicoamento de Pessoal de Nivel
   Superior (CAPES)
RP de Souza, GMC (通讯作者)，Rua Timbiras 3642,Sala 504, BR-30140062 Belo Horizonte, MG, Brazil.
EM gustavomcsouza@gmail.com
RI ; Sternick, Marcelo/G-2024-2014
OI Steponavicius Sobral, Christiane/0000-0003-3924-147X; Amorim,
   Camila/0000-0002-9090-5158; Souza, Gustavo/0000-0003-0868-6505;
   Sternick, Marcelo/0000-0002-3631-7734
CR Hultman CS, 2014, ANN PLAS SURG, V72, pS202, DOI 10.1097/SAP.0000000000000089
   Kao HK, 2015, BRIT J SURG, V102, P998, DOI 10.1002/bjs.9826
   LIMA RENAN VICTOR KÜMPEL SCHMIDT, 2017, Rev. Col. Bras. Cir., V44, P81, DOI [10.1590/0100-69912017001001, 10.1590/0100-69912017001001]
   Ojansivu M, 2018, EUR CELLS MATER, V35, P54, DOI 10.22203/eCM.v035a05
NR 4
TC 0
Z9 1
U1 1
U2 3
PU ACTA CIRURGICA BRASILEIRA
PI SAO PAULO
PA ALAMEDA RIO CLARO, 179-41, SAO PAULO, SP 01332-010, BRAZIL
SN 0102-8650
EI 1678-2674
J9 ACTA CIR BRAS
JI Acta Cir. Bras.
PY 2019
VL 34
IS 9
AR UNSP e201900907
DI 10.1590/s0102-865020190090000007
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA JR7HL
UT WOS:000499791700006
PM 31800680
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Heilani, MW
   Teubner, D
   Haist, T
   Knabe, M
   Malkomes, P
   Michael, FA
   Stumpf, M
   Zeuzem, S
   Bechstein, WO
   Friedrich-Rust, M
   Dultz, G
AF Heilani, Myriam W.
   Teubner, Daniel
   Haist, Thomas
   Knabe, Mate
   Malkomes, Patrizia
   Michael, Florian Alexander
   Stumpf, Michael
   Zeuzem, Stefan
   Bechstein, Wolf Otto
   Friedrich-Rust, Mireen
   Dultz, Georg
TI Closing the gap: endoscopic treatment of esophageal anastomotic
   leakage-a retrospective cohort study
SO SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
LA English
DT Article
DE Anastomotic leakage; Esophageal defects; Endoscopic vacuum therapy;
   Endoscopic vacuum-assisted closure; Esosponge; SEMS
ID VACUUM-ASSISTED CLOSURE; DEFECT CLOSURE; THERAPY; STENT; COMPLICATIONS;
   SMOKING
AB Background A variety of endoscopic techniques are available for the closure of esophageal defects, each offering distinct advantages. Endoscopic vacuum therapy (EVT) has emerged as a highly effective approach. Alternatively, fully covered self-expanding metal stents (SEMS) can be placed intraluminally until defect closure is achieved. For smaller defects, over-the-scope clips (OTSC (R)) provide a viable option. However, comparative data remain limited and reported closure rates vary widely across the literature. This study aimed to evaluate and compare closure rates of postoperative anastomotic leaks treated with EVT, SEMS, and OTSC (R) at two specialized centers in Germany. Methods This retrospective study included all patients treated endoscopically for anastomotic leakage at two tertiary gastroenterological centers between May 2007 and February 2023. The primary endpoint was successful endoscopic defect closure. Secondary endpoints included in-hospital mortality, need for revision surgery, duration of therapy, hospital stay length, time to treatment initiation, and procedure-related complications.<br /> Results A total of 59 patients (71% male, mean age 64 years) were included. In 94.9% of cases, surgery was performed for oncologic indications; 46% had received neoadjuvant therapy. The most common procedure was Ivor Lewis esophagectomy (89.8%). EVT was used in 24 patients, SEMS in 32, and OTSC (R) in 14. The overall closure rate was 78.0%. Patients with successful closure had a significantly lower ASA score (p = 0.039), smaller defects (<= 1 cm: 57.8% vs. 15.4%, p = 0.007), lower in-hospital mortality (2.2% vs. 38.5%, p < 0.001), and reduced need for revision surgery (0% vs. 61.5%, p < 0.001).<br /> Conclusions The success of endoscopic therapy is closely linked to patient health status and defect size. Notably, esophageal defects <= 1 cm can almost always be closed successfully using endoscopic methods.
C1 [Heilani, Myriam W.; Michael, Florian Alexander; Zeuzem, Stefan; Friedrich-Rust, Mireen; Dultz, Georg] Goethe Univ Frankfurt, Univ Hosp, Med Clin 1, Frankfurt, Germany.
   [Teubner, Daniel; Stumpf, Michael] Helios Dr Horst Schmidt Kliniken, Wiesbaden, Germany.
   [Haist, Thomas] Asklepios Paulinenklin Wiesbaden, Wiesbaden, Germany.
   [Knabe, Mate] Bethanien Hosp, Ctr Gastroenterol Bethanien, Frankfurt, Germany.
   [Malkomes, Patrizia] Ruhr Univ Bochum, Knappschaft Kliniken Univ Hosp Bochum, Dept Surg, Bochum, Germany.
   [Bechstein, Wolf Otto] Goethe Univ Frankfurt, Univ Hosp, Dept Gen Visceral Transplant & Thorac Surg, Frankfurt, Germany.
C3 Goethe University Frankfurt; Goethe University Frankfurt Hospital; Ruhr
   University Bochum; Goethe University Frankfurt; Goethe University
   Frankfurt Hospital
RP Heilani, MW (通讯作者)，Goethe Univ Frankfurt, Univ Hosp, Med Clin 1, Frankfurt, Germany.
EM heilani@med.uni-frankfurt.de
RI /AAE-2986-2019; Michael, Florian/HCH-8091-2022
OI Heilani, Myriam/0000-0002-0948-2777
FU Projekt DEAL
FX Open Access funding enabled and organized by Projekt DEAL.
CR Ahrens M, 2010, ENDOSCOPY, V42, P693, DOI 10.1055/s-0030-1255688
   Ambrose JA, 2004, J AM COLL CARDIOL, V43, P1731, DOI 10.1016/j.jacc.2003.12.047
   Bartell N, 2020, WORLD J GASTROENTERO, V26, P3495, DOI 10.3748/wjg.v26.i24.3495
   Bartels H, 2008, CHIRURG, V79, P30, DOI 10.1007/s00104-007-1441-2
   Berlth F, 2019, J GASTROINTEST SURG, V23, P67, DOI 10.1007/s11605-018-4000-x
   Bludau M, 2018, SURG ENDOSC, V32, P1906, DOI 10.1007/s00464-017-5883-4
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Chon SH, 2023, SURG ENDOSC, V37, P741, DOI 10.1007/s00464-022-09754-1
   Dasari BVM, 2014, ANN SURG, V259, P852, DOI 10.1097/SLA.0000000000000564
   Fabbi M, 2021, DIS ESOPHAGUS, V34, DOI 10.1093/dote/doaa039
   Forder A, 2023, INT J MOL SCI, V24, DOI 10.3390/ijms24032859
   Fuccio L, 2016, ENDOSCOPY, V48, P141, DOI 10.1055/s-0034-1393331
   Goto O, 2017, ENDOSCOPY, V49, P792, DOI 10.1055/s-0043-110668
   Guo S, 2010, J DENT RES, V89, P219, DOI 10.1177/0022034509359125
   Jena A, 2023, SURG ENDOSC, V37, P3410, DOI 10.1007/s00464-023-09893-z
   Klevebro F, 2016, LANGENBECK ARCH SURG, V401, P323, DOI 10.1007/s00423-016-1409-0
   Kouladouros K, 2021, SCAND J GASTROENTERO, V56, P193, DOI 10.1080/00365521.2020.1861645
   Kuehn F, 2017, SURG ENDOSC, V31, P3449, DOI 10.1007/s00464-016-5404-x
   Lange J, 2023, SURG ENDOSC, V37, P3657, DOI 10.1007/s00464-023-09861-7
   Laukoetter MG, 2017, SURG ENDOSC, V31, P2687, DOI 10.1007/s00464-016-5265-3
   Le TM, 2025, CLIN ENDOSC, V58, P181, DOI 10.5946/ce.2024.150
   Leeds SG, 2019, J GASTROINTEST SURG, V23, P1037, DOI 10.1007/s11605-018-04082-z
   Loske G, 2019, CHIRURG, V90, pS1, DOI 10.1007/s00104-018-0727-x
   Loske G, 2018, CHIRURG, V89, P952, DOI 10.1007/s00104-018-0728-9
   Low DE, 2019, ANN SURG, V269, P291, DOI 10.1097/SLA.0000000000002611
   Mahmoud T, 2022, GASTROINTEST ENDOSC, V95, P373, DOI 10.1016/j.gie.2021.10.018
   Min YW, 2019, BMC SURG, V19, DOI 10.1186/s12893-019-0497-5
   Plum PS, 2019, WORLD J SURG, V43, P862, DOI 10.1007/s00268-018-4832-2
   Quattrini C, 2008, REDUCED VASCULAR END
   Richter F, 2022, BJS OPEN, V6, DOI 10.1093/bjsopen/zrac030
   Schaheen L, 2014, AM J SURG, V208, P536, DOI 10.1016/j.amjsurg.2014.05.011
   Schorsch T, 2013, SURG ENDOSC, V27, P2040, DOI 10.1007/s00464-012-2707-4
   Sorensen LT, 2009, J SURG RES, V152, P224, DOI 10.1016/j.jss.2008.02.066
   Walle CV, 2012, INT J RADIAT ONCOL, V82, pE513, DOI 10.1016/j.ijrobp.2011.05.071
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Witte SR, 2019, ANN LAPAROSC ENDOSC, V4, DOI 10.21037/ales.2019.06.10
NR 36
TC 3
Z9 3
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0930-2794
EI 1432-2218
J9 SURG ENDOSC
JI Surg. Endosc.
PD SEP
PY 2025
VL 39
IS 9
BP 5643
EP 5653
DI 10.1007/s00464-025-11904-0
EA JUL 2025
PG 11
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 6XH3Y
UT WOS:001528757500001
PM 40659949
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Miranda-Díaz, AG
   Hermosillo-Sandoval, JM
   Gutiérrez-Martínez, CA
   Rodríguez-Carrizalez, AD
   Román-Pintos, LM
   Cardona-Muñoz, EG
   Pacheco-Moisés, FP
   Arias-Carvajal, O
AF Guillermina Miranda-Diaz, Alejandra
   Manuel Hermosillo-Sandoval, Jose
   Alberto Gutierrez-Martinez, Carlos
   Daniel Rodriguez-Carrizalez, Adolfo
   Miguel Roman-Pintos, Luis
   German Cardona-Munoz, Ernesto
   Paul Pacheco-Moises, Fermin
   Arias-Carvajal, Oscar
TI Effect of necrosectomy and vacuum-assisted closure (VAC) on
   mitochondrial function and oxidative stress markers in severe acute
   pancreatitis
SO REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
LA Spanish
DT Article
DE Acute pancreatitis; Mitochondrial dysfunction; Oxidative stress; Severe
   acute pancreatitis
ID NITRIC-OXIDE; CLINICAL CHARACTERISTICS; SUPEROXIDE-DISMUTASE;
   MEMBRANE-FLUIDITY; FREE-RADICALS; ATP SYNTHASE; ABNORMALITIES;
   ANTIOXIDANT; METABOLISM; PREDICTION
AB Background: Severe acute pancreatitis (SAP) is associated with high morbidity and mortality.
   Objective: To evaluate whether necrosectomy, alone or combined with vacuum-assisted closure (VAC), has any additional beneficial effects on mitochondrial function and/or oxidative stress markers in SAP.
   Methods: Patients with SAP, APACHE II score > 8, and inadequate response to management in an intensive care unit were included in a prospective observational study. Sixteen underwent necrosectomy and 24 underwent necrosectomy plus VAC every 48 h. Patients were then categorized as survivors or deceased. Submitochondrial membrane fluidity of platelets and F0F1-ATPase hydrolysis were measured to represent mitochondrial function. Oxidative/nitrosative stress was measured using lipoperoxides (LPOs), nitric oxide (NO), erythrocyte membrane fluidity, and total antioxidant capacity (TAC).
   Results: Membrane fluidity in submitochondrial particles of platelets remained significantly increased throughout the study, and then eventually rised in deceased patients managed with necrosectomy + VAC vs. survivors (p < 0.041). Hydrolysis was significantly increased from baseline to endpoint in all patients, predominating in those who died after management with necrosectomy (p < 0.03). LPO increased in all patients, and necrosectomy was more efficient for the eventual decrease in survivors (p < 0.039). NO was found to be increased for the baseline-endpoint result among both survivors and deceased patients with both management options. Erythrocyte membrane fluidity was increased in survivors managed with necrosectomy + VAC, and eventually returned to normal (p < 0.045). TAC was found to be consumed in all patients for the duration of the study.
   Conclusions: Mitochondrial dysfunction and oxidative/nitrosative stress with significant systemic antioxidant consumption were found. Necrosectomy was more efficient and better cleared LPOs. Necrosectomy + VAC improved erythrocyte membrane fluidity and increased survival.
C1 [Guillermina Miranda-Diaz, Alejandra; Daniel Rodriguez-Carrizalez, Adolfo; Miguel Roman-Pintos, Luis; German Cardona-Munoz, Ernesto; Arias-Carvajal, Oscar] Univ Guadalajara, Ctr Univ Ciencias Salud, Dept Fisiol, Guadalajara 44430, Jalisco, Mexico.
   [Manuel Hermosillo-Sandoval, Jose] Inst Mexicano Seguro Social, Hosp Especialidades, Ctr Med Nacl Occidente, Dept Cirugia Gen, Guadalajara, Jalisco, Mexico.
   [Alberto Gutierrez-Martinez, Carlos] Inst Mexicano Seguro Social, Hosp Especialidades, Ctr Med Nacl Occidente, Unidad Cuidados Intens, Guadalajara, Jalisco, Mexico.
   [Paul Pacheco-Moises, Fermin] Univ Guadalajara, Dept Quim, Guadalajara 44430, Jalisco, Mexico.
C3 Universidad de Guadalajara; Instituto Mexicano del Seguro Social;
   Instituto Mexicano del Seguro Social; Universidad de Guadalajara
RP Miranda-Díaz, AG (通讯作者)，Univ Guadalajara, Ctr Univ Ciencias Salud, Guadalajara 44430, Jalisco, Mexico.
EM kindalex1@outlook.com
RI Román Pintos, Luis Miguel/B-8464-2014; pacheco-moises,
   fermin/ISB-3118-2023
OI Román Pintos, Luis Miguel/0000-0002-5180-3810; CARDONA MUÑOZ, ERNESTO
   GERMAN/0000-0001-7868-667X; pacheco-moises, fermin/0000-0002-3769-5649
CR Abu-Hilal M, 2006, J PANCREAS, V7, P185
   Al Mofleh IA, 2008, WORLD J GASTROENTERO, V14, P675, DOI 10.3748/wjg.14.675
   Albrecht EWJA, 2003, J PATHOL, V199, P8, DOI 10.1002/path.1250
   Banks PA, 2002, GASTROINTEST ENDOSC, V56, pS226, DOI 10.1067/mge.2002.129022
   Banks PA, 2006, AM J GASTROENTEROL, V101, P2379, DOI 10.1111/j.1572-0241.2006.00856.x
   Bansal D, 2011, SAUDI J GASTROENTERO, V17, P174, DOI 10.4103/1319-3767.80379
   Baracca A, 2000, J BIOL CHEM, V275, P4177, DOI 10.1074/jbc.275.6.4177
   Bosetti F, 2002, NEUROBIOL AGING, V23, P371, DOI 10.1016/S0197-4580(01)00314-1
   Carrizo PH, 1998, MEDICINA-BUENOS AIRE, V58, P367
   Devanath A, 2009, INDIAN J CLIN BIOCHE, V24, P361, DOI 10.1007/s12291-009-0065-3
   Erusalimsky JD, 2007, ARTERIOSCL THROM VAS, V27, P2524, DOI 10.1161/ATVBAHA.107.151167
   FUKUYAMA H, 1994, J NUCL MED, V35, P1
   Galley HF, 1996, CRIT CARE MED, V24, P1649, DOI 10.1097/00003246-199610000-00008
   Ghasemi A., 2007, J Med Sci Res, V2, P29
   Gloor B, 2001, BJS-BRIT J SURG, V88, P975, DOI 10.1046/j.0007-1323.2001.01813.x
   Khanna Ajay K, 2013, HPB Surg, V2013, P367581, DOI 10.1155/2013/367581
   Kleinhans H, 2006, WORLD J GASTROENTERO, V12, P2914, DOI 10.3748/wjg.v12.i18.2914
   Kong L, 2004, WORLD J GASTROENTERO, V10, P3336, DOI 10.3748/wjg.v10.i22.3336
   Kowalczyk E, 2012, MOL BIOL REP, V39, P11113, DOI 10.1007/s11033-012-2017-x
   Leverve XM, 2007, CRIT CARE MED, V35, pS454, DOI 10.1097/01.CCM.0000278044.19217.73
   Marinis Athanasios, 2013, Infez Med, V21, P305
   Mohanakumar KP, 2002, ANN NY ACAD SCI, V962, P389, DOI 10.1111/j.1749-6632.2002.tb04083.x
   Ortiz GG, 2008, DIS MARKERS, V24, P151, DOI 10.1155/2008/642120
   Park BK, 2003, WORLD J GASTROENTERO, V9, P2266
   Pavlidis P, 2013, CRIT CARE RES PRACT, V2013, DOI 10.1155/2013/897107
   Pearce CB, 2006, PANCREATOLOGY, V6, P123, DOI 10.1159/000090032
   Roth E, 2004, CURR OPIN CLIN NUTR, V7, P161, DOI 10.1097/00075197-200403000-00010
   SANFEY H, 1984, ANN SURG, V200, P405, DOI 10.1097/00000658-198410000-00003
   Tao HQ, 2004, WORLD J GASTROENTERO, V10, P919
   Thareja Sandeep, 2009, Trop Gastroenterol, V30, P26
   Tiao Mao-Meng, 2009, Chang Gung Med J, V32, P346
   Tsuda K, 2003, AM J HYPERTENS, V16, P259, DOI 10.1016/S0895-7061(02)03257-0
   Vasiliadis K, 2013, ISRN Surg, V2013, P579435, DOI 10.1155/2013/579435
   Wang X, 2010, J GASTROEN HEPATOL, V25, P1386, DOI 10.1111/j.1440-1746.2010.06376.x
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
   Yamakura F, 1998, J BIOL CHEM, V273, P14085, DOI 10.1074/jbc.273.23.14085
   Zagli G, 2011, CASE REP ANESTHESIOL, V2011
   Zhao TQ, 2006, BIOCHEM BIOPH RES CO, V341, P1066, DOI 10.1016/j.bbrc.2006.01.067
   Zicha J, 1999, AM J HYPERTENS, V12, P315, DOI 10.1016/S0895-7061(98)00178-2
NR 39
TC 1
Z9 2
U1 0
U2 4
PU ARAN EDICIONES, S A
PI MADRID
PA CASTELLO, 128, 1O, 28006 MADRID, SPAIN
SN 1130-0108
EI 2340-4167
J9 REV ESP ENFERM DIG
JI Rev. Esp. Enferm. Dig.
PD SEP-DEC
PY 2014
VL 106
IS 8
BP 505
EP 514
PG 10
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA AZ5OQ
UT WOS:000348270400002
PM 25544407
DA 2026-07-24
ER

PT J
AU Sjögren, J
   Malmsjö, M
   Gustafsson, R
   Ingemansson, R
AF Sjogren, Johan
   Malmsjo, Malin
   Gustafsson, Ronny
   Ingemansson, Richard
TI Poststernotomy mediastinitis:: a review of conventional surgical
   treatments, vacuum-assisted closure therapy and presentation of the Lund
   University Hospital mediastinitis algorithm
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Review
DE mediastinitis; wound closure; thoracic surgery; review
ID STERNAL WOUND-INFECTION; OPEN-HEART-SURGERY; RIGHT-VENTRICULAR RUPTURE;
   LONG-TERM SURVIVAL; RISK-FACTORS; FLAP RECONSTRUCTION; SUCTION DRAINAGE;
   CARDIAC-SURGERY; REDON CATHETERS; MUSCLE FLAPS
AB Poststernotomy mediastinitis, also commonly called deep sternal wound infection, is one of the most feared complications in patients undergoing cardiac surgery. The overall incidence of poststernotomy mediastinitis is relatively low, between 1% and 3%, however, this complication is associated with a significant mortality, usually reported to vary between 10% and 25%. At the present time, there is no general consensus regarding the appropriate surgical approach to mediastinitis following open-heart surgery and a wide range of wound-heating strategies have been established for the treatment of poststernotomy mediastinitis during the era of modern cardiac surgery. Conventional forms of treatment usually involve surgical revision with open dressings or closed irrigation, or reconstruction with vascularized soft tissue flaps such as omentum or pectoral muscle. Unfortunately, procedure-related morbidity is relatively frequent when using conventional treatments and the tong-term clinical outcome has been unsatisfying. Vacuum-assisted closure is a novel treatment with an ingenious mechanism. This wound-heating technique is based on the application of local negative pressure to a wound. During the application of negative pressure to a sternal wound several advantageous features from conventional surgical treatment are combined. Recent publications have demonstrated encouraging clinical results, however, observations are still rather limited and the underlying mechanisms are largely unknown. This review provides an overview of the etiology and common risk factors for deep sternal wound infections and presents the historical development of conventional therapies. We also discuss the current experiences with VAC therapy in poststernotomy mediastinitis and summarize the current knowledge on the mechanisms by which VAC therapy promotes wound heating. Finally, we suggest a structured algorithm for using VAC therapy for treatment of poststernotomy mediastinitis in clinical practice. (c) 2006 Elsevier B.V. All rights reserved.
C1 Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden.
   Univ Lund Hosp, Dept Internal Med, SE-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital
RP Sjögren, J (通讯作者)，Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden.
EM johan.sjogren@med.lu.se
RI ; Sjögren, Johan/AAZ-6448-2021
OI Ingemansson, Richard/0000-0001-7623-8953; Maljö,
   Malin/0000-0001-9849-9599
CR Abboud CS, 2004, ANN THORAC SURG, V77, P676, DOI 10.1016/S0003-4975(03)01523-6
   Agarwal JP, 2005, PLAST RECONSTR SURG, V116, P1035, DOI 10.1097/01.prs.0000178401.52143.32
   Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Banwell P E, 1999, J Wound Care, V8, P79
   Banwell P E, 2003, J Wound Care, V12, P22
   Baskett RJF, 1999, ANN THORAC SURG, V67, P462, DOI 10.1016/S0003-4975(98)01195-3
   Bennett D, 2002, PLAST SURG RES COUNC
   Bitkover CY, 1998, ANN THORAC SURG, V65, P36, DOI 10.1016/S0003-4975(97)01003-5
   Borger MA, 1998, ANN THORAC SURG, V65, P1050, DOI 10.1016/S0003-4975(98)00063-0
   Braxton John H, 2004, Semin Thorac Cardiovasc Surg, V16, P70
   Brunet F, 1996, J THORAC CARDIOV SUR, V111, P1200
   BRYANT LR, 1969, ANN SURG, V169, P914, DOI 10.1097/00000658-196906000-00011
   Calvat S, 1996, ANN THORAC SURG, V61, P195, DOI 10.1016/0003-4975(95)00921-3
   CARTIER R, 1993, J THORAC CARDIOV SUR, V106, P1036, DOI 10.1016/S0022-5223(19)33974-1
   Catarino PA, 2000, ANN THORAC SURG, V70, P1891, DOI 10.1016/S0003-4975(00)02173-1
   Chen KD, 1999, J BIOL CHEM, V274, P18393, DOI 10.1074/jbc.274.26.18393
   CHERRY GW, 1983, PLAST RECONSTR SURG, V72, P680, DOI 10.1097/00006534-198311000-00018
   Cimochowski GE, 2001, ANN THORAC SURG, V71, P1572, DOI 10.1016/S0003-4975(01)02519-X
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   Crabtree Traves D, 2004, Semin Thorac Cardiovasc Surg, V16, P53
   De Feo M, 2003, ANN THORAC SURG, V75, P538, DOI 10.1016/S0003-4975(02)04313-8
   DEMMY TL, 1990, ANN THORAC SURG, V49, P458, DOI 10.1016/0003-4975(90)90256-6
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   Doss M, 2002, EUR J CARDIO-THORAC, V22, P934, DOI 10.1016/S1010-7940(02)00594-8
   Douville EC, 2004, ANN THORAC SURG, V78, P1659, DOI 10.1016/j.athoracsur.2004.04.082
   DURANDY Y, 1989, J THORAC CARDIOV SUR, V97, P282
   Eagle KA, 1999, J AM COLL CARDIOL, V34, P1262, DOI 10.1016/S0735-1097(99)00389-7
   Fleck TM, 2004, ANN PLAS SURG, V52, P310, DOI 10.1097/01.sap.0000105524.75597.e0
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Fuchs U, 2005, ANN THORAC SURG, V79, P526, DOI 10.1016/j.athoracsur.2004.08.032
   Furnary AP, 1999, ANN THORAC SURG, V67, P352, DOI 10.1016/S0003-4975(99)00014-4
   Gårdlund B, 2002, EUR J CARDIO-THORAC, V21, P825, DOI 10.1016/S1010-7940(02)00084-2
   GROSSI EA, 1985, ANN THORAC SURG, V40, P214, DOI 10.1016/S0003-4975(10)60030-6
   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   Immer FF, 2005, ANN THORAC SURG, V80, P957, DOI 10.1016/j.athoracsur.2005.03.035
   Jakob HG, 2000, EUR J CARDIO-THORAC, V17, P154, DOI 10.1016/S1010-7940(00)00327-4
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   Kirsch M, 2001, ANN THORAC SURG, V71, P1580, DOI 10.1016/S0003-4975(01)02452-3
   Klesius AA, 2004, EUR J CARDIO-THORAC, V25, P218, DOI 10.1016/j.ejcts.2003.11.019
   KRABATSCH T, 1995, J CARDIAC SURG, V10, P637, DOI 10.1111/j.1540-8191.1995.tb00654.x
   LEE AB, 1976, SURGERY, V80, P433
   LOOP FD, 1990, ANN THORAC SURG, V49, P179, DOI 10.1016/0003-4975(90)90136-T
   Lu JCY, 2003, EUR J CARDIO-THORAC, V23, P943, DOI 10.1016/S1010-7940(03)00137-4
   Luckraz H, 2003, J THORAC CARDIOV SUR, V125, P301, DOI 10.1067/mtc.2003.74
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Milano CA, 1999, ANN THORAC SURG, V67, P377, DOI 10.1016/S0003-4975(99)00022-3
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   MOIDL R, 2006, ZENTRALBL CHIR, V131, P189
   Morykwas MJ, 1999, J BURN CARE REHABIL, V20, P15, DOI 10.1097/00004630-199901001-00003
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2004, TOPICAL NEGATIVE PRE, P39
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Munoz P, 1997, CLIN INFECT DIS, V25, P1060, DOI 10.1086/516068
   NAGACHINTA T, 1987, J INFECT DIS, V156, P967, DOI 10.1093/infdis/156.6.967
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   OLENIUS M, 1993, PLAST RECONSTR SURG, V91, P213, DOI 10.1097/00006534-199302000-00001
   OTTINO G, 1987, ANN THORAC SURG, V44, P173, DOI 10.1016/S0003-4975(10)62035-8
   Piwnica A, 1988, Eur J Cardiothorac Surg, V2, P172, DOI 10.1016/1010-7940(88)90066-8
   Rand RP, 1998, ANN THORAC SURG, V65, P1046, DOI 10.1016/S0003-4975(98)00087-3
   Ridderstolpe L, 2001, EUR J CARDIO-THORAC, V20, P1168, DOI 10.1016/S1010-7940(01)00991-5
   RINGELMAN PR, 1994, PLAST RECONSTR SURG, V93, P1208, DOI 10.1097/00006534-199405000-00015
   Routledge Tom, 2005, J Heart Lung Transplant, V24, P1444, DOI 10.1016/j.healun.2004.12.111
   SARR MG, 1984, ANN THORAC SURG, V38, P415, DOI 10.1016/S0003-4975(10)62300-4
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   SHAFIR R, 1994, J CARDIOVASC SURG, V35, P103
   Shibata T, 2003, ANN THORAC SURG, V76, P956, DOI 10.1016/S0003-4975(03)00438-7
   SHUMACKER HB, 1963, ARCH SURG-CHICAGO, V86, P384
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjögren J, 2005, ANN THORAC SURG, V80, P1270, DOI 10.1016/j.athoracsur.2005.04.010
   Sjögren J, 2004, J HEART LUNG TRANSPL, V23, P506, DOI 10.1016/S1053-2498(03)00224-9
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Stahle E, 1997, EUR J CARDIO-THORAC, V11, P1146, DOI 10.1016/S1010-7940(97)01210-4
   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
   Tegnell A, 2000, ANN THORAC SURG, V69, P1104, DOI 10.1016/S0003-4975(99)01563-5
   Thomas G.P.L., 2004, SURG WOUNDS, P109
   Toumpoulis IK, 2005, CHEST, V127, P464, DOI 10.1378/chest.127.2.464
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Wettstein R, 2002, J THORAC CARDIOV SUR, V123, P1185, DOI 10.1067/mtc.2002.121304
   Yuen JC, 1995, ANN PLAS SURG, V35, P585, DOI 10.1097/00000637-199512000-00005
   Yuh DD, 2005, ANN THORAC SURG, V80, P1493, DOI 10.1016/j.athoracsur.2004.03.043
NR 86
TC 206
Z9 236
U1 0
U2 9
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
EI 1873-734X
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD DEC
PY 2006
VL 30
IS 6
BP 898
EP 905
DI 10.1016/j.ejcts.2006.09.020
PG 8
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 117WU
UT WOS:000242904800014
PM 17056269
OA Bronze
DA 2026-07-24
ER

PT J
AU Cothren, CC
   Moore, EE
   Johnson, JL
   Moore, JB
   Burch, JM
AF Cothren, C. Clay
   Moore, Ernest E.
   Johnson, Jeffrey L.
   Moore, John B.
   Burch, Jon M.
TI One hundred percent fascial approximation with sequential abdominal
   closure of the open abdomen
SO AMERICAN JOURNAL OF SURGERY
LA English
DT Article
DE open abdomen; trauma; damage control surgery; abdominal compartment
   syndrome; closure
ID VACUUM PACK TECHNIQUE; VENTRAL HERNIA
AB Background: Damage-control surgery and the recognition of the abdominal compartment syndrome have improved patient outcomes but at the cost of an open abdomen. Multiple techniques have been introduced to obtain fascial closure for the open abdomen to minimize morbidity and cost of care. We performed a modification of the vacuum-assisted closure (VAC) technique that provided constant fascial tension, hypothesizing this would result in a higher rate of primary fascial closure.
   Methods:. After initial temporary closure of the abdomen after post-injury damage control or decompressive laparotomy for abdominal compartment syndrome, we began the sequential closure technique. The technique begins by covering the bowel with the multiple white sponges overlapped like patchwork, and the fascia is placed under moderate tension over the white sponges with #1-PDS sutures. Large black VAC sponges are placed on top of the white sponges and affixed with an occlusive dressing and standard suction tubing is placed. Patients are returned to the operating room for sequential fascial closure and replacement of the sponge sandwich every 2 days, with a resulting decrease in the fascial defect.
   Results: Fourteen patients underwent sequential abdominal closure during,the study period: 9 owing to damage control surgery and 5 owing to secondary abdominal compartment syndrome. Average time to closure was 7.5 +/- 1.0 days (range 4-16) and average number of laparotomies to closure was 4.6 +/- 0.5 (range 3-8). All patients attained primary fascial closure.
   Conclusion: We propose a modification of the previously described vacuum-assisted closure technique that achieves 100% fascial approximation in our limited experience. Further application and refinement of this technique may eliminate the need for delayed complex and costly reconstructive abdominal wall procedures for the open abdomen. (c) 2006 Excerpta Medica Inc. All rights reserved.
C1 Denver Hlth Med Ctr, Dept Surg, Denver, CO 80204 USA.
   Univ Colorado, Hlth Sci Ctr, Denver, CO USA.
C3 Denver Health Medical Center; University of Colorado System; University
   of Colorado Anschutz; University of Colorado Denver
RP Cothren, CC (通讯作者)，Denver Hlth Med Ctr, Dept Surg, 777 Bannock St,MC 0206, Denver, CO 80204 USA.
EM clay.cothren@dhha.org
CR Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Cipolla J, 2005, AM SURGEON, V71, P202
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Miller PR, 2002, J TRAUMA, V53, P843, DOI 10.1097/00005373-200211000-00007
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   Scott BG, 2005, SCAND J SURG, V94, P9, DOI 10.1177/145749690509400104
   Stonerock CE, 2003, AM SURGEON, V69, P1030
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Tremblay LN, 2001, AM J SURG, V182, P670, DOI 10.1016/S0002-9610(01)00805-4
NR 9
TC 127
Z9 137
U1 0
U2 4
PU EXCERPTA MEDICA INC
PI BRIDGEWATER
PA 685 ROUTE 202-206, BRIDGEWATER, NJ 08807 USA
SN 0002-9610
J9 AM J SURG
JI Am. J. Surg.
PD AUG
PY 2006
VL 192
IS 2
BP 238
EP 242
DI 10.1016/j.amjsurg.2006.04.010
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 071EK
UT WOS:000239580900018
PM 16860637
DA 2026-07-24
ER

PT J
AU Halvorson, J
   Jinnah, R
   Kulp, B
   Frino, J
AF Halvorson, Jason
   Jinnah, Riyaz
   Kulp, Brenda
   Frino, John
TI Use of Vacuum-assisted Closure in Pediatric Open Fractures With a Focus
   on the Rate of Infection
SO ORTHOPEDICS
LA English
DT Article
ID PRESSURE WOUND THERAPY; OPEN TIBIAL FRACTURES; CHILDREN; EXPERIENCE;
   MANAGEMENT; POPULATION; INJURIES
AB The use of the vacuum-assisted closure device (VAC; KCI, San Antonio, Texas) has given the orthopedist a new tool for the successful management of severe traumatic wounds and open fractures. While the VAC's role in the adult population is proving itself as an improved therapy compared to "traditional wound care," it's role within pediatric orthopedics remains less well defined. Questions remain whether VAC therapy provides benefit regarding decreased infection rates as well as decreased need for extensive soft tissue coverage procedures. A review was therefore performed of a pediatric level I trauma center's experience using the VAC therapy for pediatric open fractures with a focus on the rate of superficial, deep, and chronic infection. A retrospective chart review spanning 4.5 years of all pediatric patients younger than 18 years with an open fracture initially treated with VAC therapy was conducted at a level I pediatric trauma center. This yielded 28 patients with 37 open fractures aged 2 to 17 years who were initially treated with wound VAC therapy. Subsequent chart review of these patients was performed examining in-hospital records, operative notes, and clinical follow-up visits for documented cases of superficial, deep, or chronic infection. Of 37 open pediatric fractures treated with a wound VAC, there were no cases of superficial infection and 2 cases of deep infection for an overall infection rate of 5%. Both infections resolved with surgical intervention and antibiotics without chronic infection development. When compared with historical controls, the use of VAC therapy for pediatric open fractures appears to be an equally safe and effective modality to help reduce infection in pediatric open fractures and should be considered a valuable tool in treating these injuries.
C1 [Halvorson, Jason; Jinnah, Riyaz; Kulp, Brenda; Frino, John] Wake Forest Baptist Hlth, Dept Orthoped Surg, Winston Salem, NC 27103 USA.
C3 Wake Forest University; Wake Forest Baptist Medical Center
RP Halvorson, J (通讯作者)，Wake Forest Baptist Hlth, Dept Orthoped Surg, Med Ctr Blvd, Winston Salem, NC 27103 USA.
EM jhalvors@wfubmc.edu
FU KCI, San Antonio, Texas
FX In support of the research and preparation of this article, the
   Department of Orthopedic Surgery at Wake Forest Baptist Health received
   grants or outside funding from KCI, San Antonio, Texas.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Baharestani MM, 2007, OSTOMY WOUND MANAG, V53, P75
   Bartlett CS, 1997, J ORTHOP TRAUMA, V11, P357, DOI 10.1097/00005131-199707000-00010
   Buckley SL, 1996, J PEDIATR ORTHOPED, V16, P627, DOI 10.1097/01241398-199609000-00015
   Bütter A, 2006, J PEDIATR SURG, V41, P940, DOI 10.1016/j.jpedsurg.2006.01.061
   Canavese F, 2008, J BONE JOINT SURG BR, V90B, P377, DOI 10.1302/0301-620X.90B3.19890
   Caniano DA, 2005, J PEDIATR SURG, V40, P128, DOI 10.1016/j.jpedsurg.2004.09.016
   Contractor D, 2008, J ORTHOP TRAUMA, V22, pS167, DOI 10.1097/BOT.0b013e318188e295
   Cullen MC, 1996, J BONE JOINT SURG AM, V78A, P1039, DOI 10.2106/00004623-199607000-00008
   Dedmond BT, 2006, J PEDIATR ORTHOPED, V26, P728, DOI 10.1097/01.bpo.0000242434.58316.ad
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Doak J, 2009, J PEDIATR ORTHOPED, V29, P49, DOI 10.1097/BPO.0b013e3181901c66
   Glass GE, 2009, INJURY, V40, P876, DOI 10.1016/j.injury.2008.12.010
   Gougoulias N, 2009, BRIT MED BULL, V91, P75, DOI 10.1093/bmb/ldp019
   HOPE PG, 1992, J BONE JOINT SURG BR, V74, P546, DOI 10.1302/0301-620X.74B4.1624514
   Horn PL, 2007, ORTHOP NURS, V26, P317, DOI 10.1097/01.NOR.0000295960.94450.69
   Jones BG, 2003, INJURY, V34, P776, DOI 10.1016/S0020-1383(03)00031-7
   Joseph E, 2000, WOUNDS, V12, P60
   McCord SS, 2007, WOUND REPAIR REGEN, V15, P296, DOI 10.1111/j.1524-475X.2007.00229.x
   Mooney JF, 2000, CLIN ORTHOP RELAT R, P26
   Shilt JS, 2004, J PEDIATR ORTHOPED, V24, P482, DOI 10.1097/01241398-200409000-00006
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
NR 22
TC 17
Z9 23
U1 0
U2 10
PU SLACK INC
PI THOROFARE
PA 6900 GROVE RD, THOROFARE, NJ 08086 USA
SN 0147-7447
J9 ORTHOPEDICS
JI Orthopedics
PD JUL
PY 2011
VL 34
IS 7
BP E256
EP E260
DI 10.3928/01477447-20110526-15
PG 5
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 861TA
UT WOS:000298040900004
PM 21717985
DA 2026-07-24
ER

PT J
AU Günal, Ö
   Tuncel, U
   Turan, A
   Barut, S
   Kostakoglu, N
AF Gunal, Ozgur
   Tuncel, Umut
   Turan, Aydin
   Barut, Sener
   Kostakoglu, Naci
TI The Use of Vacuum-Assisted Closure and GranuFoam Silver® Dressing in the
   Management of Diabetic Foot Ulcer
SO SURGICAL INFECTIONS
LA English
DT Article
ID PRESSURE WOUND THERAPY; NEGATIVE-PRESSURE; ESCHERICHIA-COLI;
   NANOPARTICLES; EXPERIENCE; DIAGNOSIS; EFFICACY
AB Purpose: The aim of this retrospective study was to evaluate the efficacy of vacuum-assisted closure (VAC) and GranuFoam Silver((R)) dressing (KCI, San Antonio, TX) compared with conventional GranuFoam((R)) dressing in the management of diabetic foot ulcers. Patients and Methods: Twenty-one consecutive patients treated with conventional or silver-coated foam dressing were reviewed retrospectively. The wound duration was 6mo. Group 1 (n=10) received conventional foam dressing (GranuFoam) and group 2 (n=11) received silver-coated foam dressing (GranuFoam Silver). The wound surface area, duration of treatment, bacteriology, and recurrence were compared between the groups. The mean age of the patients was 61.7010.52y in group 1 and 67.2711.28y in group 2. Results: In group 1, the average surface area of the wounds was 45.30 +/- 46.96cm(2) and 18.40 +/- 23.48cm(2) in the pre-treatment and post-treatment periods, respectively. There was a statistically significant difference between two measurements (p=0.005). Average duration of the treatment was 25.50 +/- 27.13d in this group. In group 2, average surface area of the wounds in the pre-treatment and post-treatment periods were 41.55 +/- 36.03cm(2) and 7.64 +/- 3.91cm(2), respectively. There was a statistically significant difference between two measurements (p=0.003). Average duration of the treatment was 10.09 +/- 3.51d in this group. The patients treated with silver-impregnated polyurethane foam dressing had reduced recurrence (2 vs. 7 wounds, p=0.030) and increased number of the culture-negative cases at the end of the treatment. Conclusion: With the results of the study, it was concluded that VAC GranuFoam silver dressing can be superior to conventional GranuFoam dressing in reducing the recurrence rate of infected diabetic foot ulcers.
C1 [Gunal, Ozgur; Barut, Sener] Gaziosmanpasa Univ, Fac Med, Dept Infect Dis & Clin Microbiol, TR-60100 Tokat, Turkey.
   [Tuncel, Umut; Turan, Aydin; Kostakoglu, Naci] Gaziosmanpasa Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-60100 Tokat, Turkey.
C3 Tokat Gaziosmanpasa University; Tokat Gaziosmanpasa University
RP Günal, Ö (通讯作者)，Gaziosmanpasa Univ, Fac Med, Dept Infect Dis & Clin Microbiol, TR-60100 Tokat, Turkey.
EM ozgurgop@yahoo.com
RI Turan, Aydın/V-6669-2017; Barut, Sener/AAI-2731-2021; Gunal,
   Ozgur/I-7882-2014; Tuncel, Umut/P-3185-2015
OI Turan, Aydın/0000-0002-1540-1443; Barut, Sener/0000-0003-2047-8573;
   Gunal, Ozgur/0000-0002-7744-4123; Tuncel, Umut/0000-0001-5029-2927
CR Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Asavavisithchai S, 2010, J MATER SCI-MATER M, V21, P1329, DOI 10.1007/s10856-009-3969-9
   Cho YS, 2002, J MATER SCI-MATER M, V13, P861, DOI 10.1023/A:1016500429225
   Egemen O, 2012, INT WOUND J, V9, P199, DOI 10.1111/j.1742-481X.2011.00876.x
   Foster A V M, 1994, J Wound Care, V3, P224
   Frykberg R G, 1999, Adv Wound Care, V12, P139
   Gabriel A, 2009, INT WOUND J, V6, P1, DOI 10.1111/j.1742-481X.2009.00628.x
   Gerry R, 2007, ANN PLAS SURG, V59, P58, DOI 10.1097/01.sap.0000263420.70303.cc
   Gómez-Barrena E, 2012, J ORTHOP RES, V30, P1634, DOI 10.1002/jor.22114
   Hilton JR, 2004, CLIN INFECT DIS, V39, pS100, DOI 10.1086/383270
   Johannesson A, 2009, DIABETES CARE, V32, P275, DOI 10.2337/dc08-1639
   Jonasson JM, 2008, DIABETES CARE, V31, P1536, DOI 10.2337/dc08-0344
   Kalemikerakis J, 2012, J BUON, V17, P560
   Kim JS, 2007, NANOMED-NANOTECHNOL, V3, P95, DOI 10.1016/j.nano.2006.12.001
   Lara Humberto H., 2010, Journal of Nanobiotechnology, V8, P1, DOI [10.1186/1477-3155-8-1, 10.1186/1477-3155-8-15]
   Lee BU, 2008, J MICROBIOL BIOTECHN, V18, P176
   Leininger BE, 2006, J TRAUMA, V61, P1207, DOI 10.1097/01.ta.0000241150.15342.da
   Lepantalo M, 2001, EUR J VASC ENDOVA S2, V42, pS60
   Li WR, 2011, BIOMETALS, V24, P135, DOI 10.1007/s10534-010-9381-6
   Lipsky BA, 2004, CLIN INFECT DIS, V39, P885, DOI 10.1086/383271
   Nather A, 2010, ANN ACAD MED SINGAP, V39, P353
   Ngo QD, 2012, WOUND REPAIR REGEN, V20, P83, DOI 10.1111/j.1524-475X.2011.00747.x
   Payne JL, 2009, J BIOMED MATER RES B, V89B, P217, DOI 10.1002/jbm.b.31209
   Peel TN, 2012, CURR OPIN INFECT DIS, V25, P670, DOI 10.1097/QCO.0b013e32835915db
   Percival SL, 2005, J HOSP INFECT, V60, P1, DOI 10.1016/j.jhin.2004.11.014
   Percival SL, 2011, WOUND REPAIR REGEN, V19, P767, DOI 10.1111/j.1524-475X.2011.00739.x
   Sachsenmaier S, 2013, INJURY, V44, P1363, DOI 10.1016/j.injury.2013.07.014
   Sondi I, 2004, J COLLOID INTERF SCI, V275, P177, DOI 10.1016/j.jcis.2004.02.012
   Stacey MC, 2004, MED J AUSTRALIA, V180, P316, DOI 10.5694/j.1326-5377.2004.tb05962.x
   TAHERINEJAD F, 2008, 3 C WORLD UN WOUND H
   Thomas JG, 2011, J WOUND CARE, V20, P124, DOI 10.12968/jowc.2011.20.3.124
   Tong JWK, 2009, INT WOUND J, V6, P275, DOI 10.1111/j.1742-481X.2009.00610.x
   Tuncel U, 2012, INT WOUND J, V5, P1742
NR 33
TC 20
Z9 27
U1 1
U2 28
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD OCT 1
PY 2015
VL 16
IS 5
BP 558
EP 565
DI 10.1089/sur.2014.093
PG 8
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA CS6VT
UT WOS:000362221800014
PM 26114333
DA 2026-07-24
ER

PT J
AU Corturillo, G
   Jovanovic, M
   Rohleder, S
   Heydweiller, AC
   Muensterer, OJ
   Doll, D
   von Sochaczewski, CO
AF Corturillo, Giada
   Jovanovic, Marko
   Rohleder, Stephan
   Heydweiller, Andreas C.
   Muensterer, Oliver J.
   Doll, Dietrich
   von Sochaczewski, Christina Oetzmann
TI Practice patterns of paediatric surgeons on treating pilonidal sinus
   disease - a national survey study
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Article
DE Pilonidal sinus disease; Child; Survey; Paediatric surgery; Germany
ID METHYLENE-BLUE; PREVALENCE; RECURRENCE; GERMANY; EXCISION
AB PurposePaediatric pilonidal sinus disease is considered a separate entity of disease due to differing recurrence dynamics. However, there are almost no data on real-world surgical care and practice patterns for children and adolescents. We therefore aimed to gather such data surveying a representative sample of German paediatric surgeons.MethodsSome 101 German paediatric surgical departments and surgeries with inpatient beds were surveyed for their surgical approach to paediatric pilonidal sinus disease. The survey included demographics, information on practice setting, as well as the primary and secondary approach to pilonidal disease and three virtual patient scenarios.ResultsA total of 40 institutions (33 departments and 7 office-based paediatric surgeons) responded (recall rate 40%). Of these, 18/40 reported performing 10-20, and 9/40 perform 5-10 pilonidal sinus operations annually. 17/39 respondents have less than 10% recurrences among their patient cohort and 15/39 operate on 11-20% recurrences among their patients. The most frequently reported surgical approach was excision and secondary closure with 17/39, followed by excision and vacuum-assisted closure (13/39), and pit-picking (12/39). Intraoperative use of blue dyes report 15/39 and 29/39 continue postoperative outpatient care at their institution. Acute pilonidal sinus with abscess is treated with a two-staged approach within four weeks by 15/39 while 11 institutions wait more than four weeks until definitive surgery. In recurrent cases, the majority of 20/39 does not switch their approach, while 13/39 switch to excision and secondary closure, and 11/39 switch to excision and vacuum-assisted closure.ConclusionGerman paediatric surgeons prefer traditional approaches to pilonidal sinus diseases, but pit-picking is frequently used. Neither the adult-based national guideline recommendations nor paediatric treatment algorithms have been widely implemented. The reasons for these deviations from recommendations and favouring traditional approaches remain unclear.
C1 [Corturillo, Giada; Heydweiller, Andreas C.; von Sochaczewski, Christina Oetzmann] Univ Klinikum Bonn, Sekt Kinderchirurg Chirurg Klin, Bonn, Germany.
   [Jovanovic, Marko] Univ Klinikum Bonn, Inst Digitale Med, Venusberg Campus 1, D-53127 Bonn, Germany.
   [Rohleder, Stephan] Univ Med Mainz, Klin & Poliklin Kinderchirurg, Mainz, Germany.
   [Heydweiller, Andreas C.] St Marien Hosp Bonn, Kinderchirurg Klin, Bonn, Germany.
   [Muensterer, Oliver J.] Klinikum Ludwig Maximilians Univ Munchen, Kinderchirurg Klin & Poliklin, Dr von Haunersches Kinderspital, Munich, Germany.
   [Doll, Dietrich] St Marienhosp Vechta, Klin Proktochirurg & Pilonidalsinus, Vechta, Germany.
C3 University of Bonn; University of Bonn; Johannes Gutenberg University of
   Mainz; St. Marien Hospital; University of Munich; St. Marien Hospital
RP von Sochaczewski, CO (通讯作者)，Univ Klinikum Bonn, Sekt Kinderchirurg Chirurg Klin, Bonn, Germany.
EM c.oetzmann@gmail.com
RI ; Muensterer, Oliver/G-3953-2013; Doll, med./H-6633-2019; Oetzmann von
   Sochaczewski, Christina/ABF-5826-2020
OI Heydweiller, Aneas/0000-0002-4542-8030; Muensterer,
   Oliver/0000-0003-2790-4395; Rohleder, Stephan/0000-0001-5632-0423;
   Jovanović, Marko/0000-0003-0522-1016; Oetzmann von Sochaczewski,
   Christina/0000-0002-3469-777X
FU Projekt DEAL
FX Open Access funding enabled and organized by Projekt DEAL.
CR Andersson RE, 2019, COLOPROCTOLOGY, V41, P117, DOI 10.1007/s00053-019-0341-5
   Andler W, 2007, MONATSSCHR KINDERH, V155, P157, DOI 10.1007/s00112-007-1462-4
   Ankersen JL, 2025, COLORECTAL DIS, V27, DOI 10.1111/codi.17169
   Ardelt M, 2017, CHIRURG, V88, P961, DOI 10.1007/s00104-017-0463-7
   Aysan E, 2013, SURG TODAY, V43, P1286, DOI 10.1007/s00595-012-0433-0
   Bergus Katherine C, 2024, Ann Surg Open, V5, pe488, DOI [10.1097/as9.0000000000000488, 10.1097/AS9.0000000000000488]
   Burnett D, 2018, CUREUS J MED SCIENCE, V10, DOI 10.7759/cureus.2625
   Cai ZL, 2024, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD015213.pub2
   Carter M, 2025, J PEDIATR SURG, V60, DOI 10.1016/j.jpedsurg.2024.162056
   Check NM, 2022, J AM COLL SURGEONS, V235, P773, DOI 10.1097/XCS.0000000000000356
   Doll D, 2025, SURG OPEN SCI, V23, P50, DOI 10.1016/j.sopen.2025.01.001
   Doll D, 2008, INT J COLORECTAL DIS, V23, P839, DOI 10.1007/s00384-008-0476-2
   Doll D, 2008, INT J COLORECTAL DIS, V23, P181, DOI 10.1007/s00384-007-0393-9
   Dreznik Y, 2024, WORLD J SURG, V48, P1261, DOI 10.1002/wjs.12167
   Duman K, 2017, ASIAN J SURG, V40, P434, DOI 10.1016/j.asjsur.2016.04.001
   Engels MN, 2024, EGYPT PEDIATR ASSO, V72, DOI 10.1186/s43054-024-00305-y
   Esposito C, 2023, UPDATES SURG, V75, P1625, DOI 10.1007/s13304-023-01508-5
   Esposito C, 2020, FRONT PEDIATR, V8, DOI 10.3389/fped.2020.00345
   Esposito C, 2020, J PEDIATR SURG, V55, P761, DOI 10.1016/j.jpedsurg.2019.04.031
   Fabricius R, 2010, DAN MED BULL, V57
   Faurschou IK, 2025, COLORECTAL DIS, V27, DOI 10.1111/codi.17227
   Froehlich M, 2022, SEMIN COLON RECTAL S, V33, DOI 10.1016/j.scrs.2022.100911
   Gallo G, 2023, COLORECTAL DIS, V25, P2177, DOI 10.1111/codi.16760
   Gil LA, 2023, JAMA SURG, V158, P875, DOI 10.1001/jamasurg.2023.0373
   Giles W, 2024, PEDIATR SURG INT, V40, DOI 10.1007/s00383-024-05668-2
   Gips M, 2022, ISR MED ASSOC J, V24, P89
   Grabowski J, 2019, J PEDIATR SURG, V54, P2210, DOI 10.1016/j.jpedsurg.2019.02.055
   Gurbanov A, 2021, TURK J SURG, V37, P260, DOI 10.47717/turkjsurg.2021.5100
   Halleran DR, 2018, J SURG RES, V232, P430, DOI 10.1016/j.jss.2018.06.071
   Heydweiller A, 2021, BMC SURG, V21, DOI 10.1186/s12893-021-01371-4
   Horesh N, 2024, TECH COLOPROCTOL, V28, DOI 10.1007/s10151-023-02897-w
   Huurman EA, 2022, CUREUS J MED SCIENCE, V14, DOI 10.7759/cureus.25050
   Iacob C, 2024, PEDIATR SURG INT, V41, DOI 10.1007/s00383-024-05941-4
   Iesalnieks I, 2021, LANGENBECK ARCH SURG, V406, P2569, DOI 10.1007/s00423-020-02060-1
   Iesalnieks I, 2016, LANGENBECK ARCH SURG, V401, P599, DOI 10.1007/s00423-016-1463-7
   Khodakaram K, 2017, WORLD J SURG, V41, P1295, DOI 10.1007/s00268-016-3828-z
   Krüger CM, 2021, CHIRURG, V92, P1107, DOI 10.1007/s00104-021-01404-x
   Kuvvetli A, 2019, Turkish Journal of Colorectal Disease, V29, P118, DOI [10.4274/tjcd.galenos.2019.93764, 10.4274/tjcd.galenos.2019.93764, DOI 10.4274/TJCD.GALENOS.2019.93764]
   Lamdark T, 2020, MEDICINA-LITHUANIA, V56, DOI 10.3390/medicina56070341
   Lee MJ, 2023, COLORECTAL DIS, DOI 10.1111/codi.16696
   Lee WG, 2024, PEDIATR SURG INT, V40, DOI 10.1007/s00383-023-05629-1
   Loganathan A, 2012, DIS COLON RECTUM, V55, P491, DOI 10.1097/DCR.0b013e31823fe06c
   Luedi MM, 2021, ANZ J SURG, V91, P1582, DOI 10.1111/ans.16990
   Maasewerd SKM, 2023, WORLD J SURG, V47, P2296, DOI 10.1007/s00268-023-07045-x
   Martina A., 1905, Dtsch. Z. Chir, V80, P354, DOI [10.1007/BF02791391, DOI 10.1007/BF02791391]
   Mattei P, 2022, Fundamentals of Pediatric Surgery, P403, DOI [10.1007/978-3-031-07524-7_36, DOI 10.1007/978-3-031-07524-7_36]
   Metzger GA, 2021, ANN MED SURG, V64, DOI 10.1016/j.amsu.2021.102233
   Minneci PC, 2024, JAMA SURG, V159, P19, DOI 10.1001/jamasurg.2023.5526
   Minneci PC, 2018, TRIALS, V19, DOI 10.1186/s13063-018-2987-7
   Nasr A, 2011, CAN J SURG, V54, P39, DOI 10.1503/cjs.028509
   Nyandoro MG, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.39480
   Odlo M, 2022, BMC SURG, V22, DOI 10.1186/s12893-022-01889-1
   von Sochaczewski CO, 2021, INT J COLORECTAL DIS, V36, P2135, DOI 10.1007/s00384-021-03944-4
   von Sochaczewski CO, 2021, BMC UROL, V21, DOI 10.1186/s12894-021-00804-9
   von Sochaczewski CO, 2020, FRONT PEDIATR, V8, DOI 10.3389/fped.2020.00152
   Ommer A, 2014, COLOPROCTOLOGY, V36, P272, DOI 10.1007/s00053-014-0467-4
   Pakarinen M, 2017, EUR J PEDIATR SURG, V27, P395, DOI 10.1055/s-0037-1606635
   Pedersen N, 2025, COLORECTAL DIS, V27, DOI 10.1111/codi.17238
   Pérez-Bertólez S, 2024, TECH COLOPROCTOL, V29, DOI 10.1007/s10151-024-03049-4
   Perez-Bertolez S, 2021, Cir Pediatr, V34, P191
   Rafeeqi T, 2023, J PEDIATR SURG, V58, P532, DOI 10.1016/j.jpedsurg.2022.06.014
   Sahin A, 2014, EUR SURG, V46, P148, DOI 10.1007/s10353-014-0276-6
   Schmedding A, 2017, EUR J PEDIATR SURG, V27, P399, DOI 10.1055/s-0037-1607026
   Schneider R, 2022, EUR SURG, V54, P117, DOI 10.1007/s10353-021-00715-x
   Shlyk D, 2025, COLORECTAL DIS, V27, DOI 10.1111/codi.70020
   Shu BS, 2022, CHILDREN-BASEL, V9, DOI 10.3390/children9081264
   STEINAU G, 1993, ZBL CHIR, V118, P25
   Stoll M., 2012, Chir Praxis, V75, P467
   von Mosengeil K., 1887, Die Chirurgischen Erkrankungen I, VSechster Band. Erste Abtheilung., P378
   von Sochaczewski CO, 2024, SURGERIES-BASEL, V5, P726, DOI 10.3390/surgeries5030057
   Wijnen MHWA, 2017, EUR J PEDIATR SURG, V27, P407, DOI 10.1055/s-0037-1606839
   YUCESAN S, 1993, EUR J EPIDEMIOL, V9, P373, DOI 10.1007/BF00157393
NR 72
TC 1
Z9 1
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0179-1958
EI 1432-1262
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD JUL 28
PY 2025
VL 40
IS 1
AR 165
DI 10.1007/s00384-025-04959-x
PG 11
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 5KV9R
UT WOS:001538087000001
PM 40721961
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Cuthbert, C
   Zaghloul, T
   Bhatia, S
   Mothi, SS
   Davis, E
   Heavens, HG
   Bishop, MW
   Talbot, LJ
   Neel, MD
   Abdelhafeez, AH
AF Cuthbert, Chance
   Zaghloul, Tarek
   Bhatia, Shalini
   Mothi, Suraj Sarvode
   Davis, Erma
   Heavens, Heather G.
   Bishop, Michael W.
   Talbot, Lindsay J.
   Neel, Michael D.
   Abdelhafeez, Abdelhafeez H.
TI Use of Vacuum-Assisted Closure to Reduce the Likelihood of Wound
   Complications After Limb-Sparing Resection of Pediatric Primary Bone
   Sarcomas of the Femur
SO JOURNAL OF PEDIATRIC SURGERY
LA English
DT Article
DE Bone sarcoma; Osteosarcoma; Ewing sarcoma; Limb sparing; Wound; VAC
ID SOFT-TISSUE SARCOMA; PREOPERATIVE RADIOTHERAPY; THERAPY; SURGERY;
   CHEMOTHERAPY; PREDICTORS; TRIAL
AB Background: Limb-sparing surgery is the standard of care for primary bone tumors. However, such procedures are associated with high rates of wound complications, specifically in lower-extremity surgeries. Therefore, identifying and implementing interventions to minimize the likelihood of wound complications after limb-sparing resection of the lower extremity is crucial. Methods: Patients who underwent limb-sparing osteosarcoma or Ewing sarcoma resection during a 7year period at a single institution were retrospectively reviewed. Data were collected on 39 patients who underwent limb-sparing resection of the femur. Patient demographics, tumor characteristics, and perioperative and postoperative data were extracted and analyzed. Patients who underwent resection before April 2017 received conventional postoperative incision dressings. Starting in April 2017, patients received vacuum-assisted closure (VAC) with the 3 MTM Prevena VAC system after surgical closure. Eighteen patients received conventional postoperative incision dressing, and 21 received incisional wound VAC. A wound complication was defined as any Clavien-Dindo classification greater than 0 within a 28-day postoperative period. Results: Patients who received postoperative incisional wound VAC had lower rates of wound complications than those who received conventional incision dressings (14% vs. 50%; p = 0.035). Additionally, patients in whom wound complications developed had a longer average hospital stay than those without wound complications (5 days vs. 4 days; p = 0.029). Conclusions: Wound complications prolong the hospital stay and can delay adjuvant chemotherapy for bone tumors. The use of postoperative incisional wound VAC is associated with less likelihood of wound complications and should be considered in any high-risk surgical closure. Level of Evidence: Level III Treatment Study. (c) 2024 Elsevier Inc. All rights reserved.
C1 [Cuthbert, Chance; Zaghloul, Tarek; Talbot, Lindsay J.; Neel, Michael D.; Abdelhafeez, Abdelhafeez H.] St Jude Childrens Res Hosp, Dept Surg, MS 133,262 Danny Thomas Pl, Memphis, TN 38105 USA.
   [Zaghloul, Tarek] Cairo Univ, Natl Canc Inst, Dept Surg Oncol, Giza, Egypt.
   [Bhatia, Shalini; Mothi, Suraj Sarvode] St Jude Childrens Res Hosp, Dept Biostat, 262 Danny Thomas Pl, Memphis, TN 38105 USA.
   [Davis, Erma; Heavens, Heather G.] St Jude Childrens Res Hosp, Ctr Adv Practice, 262 Danny Thomas Pl, Memphis, TN 38105 USA.
   [Bishop, Michael W.] St Jude Childrens Res Hosp, Dept Oncol, 262 Danny Thomas Pl, Memphis, TN 38105 USA.
   [Talbot, Lindsay J.; Abdelhafeez, Abdelhafeez H.] Univ Tennessee, Hlth Sci Ctr, Dept Surg, 800 Madison Ave, Memphis, TN 38163 USA.
C3 St Jude Children's Research Hospital; Egyptian Knowledge Bank (EKB);
   National Cancer Institute - Egypt; Cairo University; St Jude Children's
   Research Hospital; St Jude Children's Research Hospital; St Jude
   Children's Research Hospital; University of Tennessee System; University
   of Tennessee Health Science Center
RP Abdelhafeez, AH (通讯作者)，St Jude Childrens Res Hosp, Dept Surg, MS 133,262 Danny Thomas Pl, Memphis, TN 38105 USA.
EM Hafeez.abdelhafeez@stjude.org
RI ; Sarvode Mothi, Suraj/JYQ-5641-2024
OI Cuthbert, Chance/0009-0004-4704-0795; Abdelhafeez,
   Abdelhafeez/0000-0002-7671-3037; Zaghloul, Tarek/0000-0001-7387-1112; 
FU American Lebanese Syrian Associated Charities (ALSAC)
FX <BOLD>Financial sources </BOLD> This work was supported by the American
   Lebanese Syrian Associated Charities (ALSAC) .
CR 3M 3M Prevena&TRADE, Incision Management System|3M
   A Novak, 2014, Open Orthop J, V8, P168, DOI 10.2174/1874325001408010168
   assessurgery, The Clavien-Dindo Classification | AssesSurgery GmbH
   Baharestani M, 2009, INT WOUND J, V6, P1, DOI 10.1111/j.1742-481X.2009.00607.x
   Baldini EH, 2013, ANN SURG ONCOL, V20, P1494, DOI 10.1245/s10434-012-2797-1
   BARKLEY HT, 1988, INT J RADIAT ONCOL, V14, P693, DOI 10.1016/0360-3016(88)90091-0
   Bedi M, 2019, CLIN ORTHOP RELAT R, V477, P768, DOI 10.1097/CORR.0000000000000371
   Bielack SS, 2015, J CLIN ONCOL, V33, P2279, DOI 10.1200/JCO.2014.60.0734
   de Jesus LE, 2018, J PEDIATR SURG, V53, P585, DOI 10.1016/j.jpedsurg.2017.11.048
   Eaton BR, 2021, PEDIATR BLOOD CANCER, V68, DOI 10.1002/pbc.28352
   Elswick SM, 2020, J SURG ONCOL, V121, P945, DOI 10.1002/jso.25830
   Gallaway Kathryn E., 2020, Sarcoma, V2020, P1283080, DOI [10.1155/2020/1283080, 10.1155/2020/1283080]
   Gallaway KE, 2020, J ONCOL, V2020, DOI 10.1155/2020/7282846
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Ichioka S, 2008, WOUND REPAIR REGEN, V16, P460, DOI 10.1111/j.1524-475X.2008.00390.x
   Imran H, 2009, J BONE JOINT SURG AM, V91A, P604, DOI 10.2106/JBJS.H.00449
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P601, DOI 10.1097/PRS.0b013e318196b97b
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P589, DOI 10.1097/PRS.0b013e3181956551
   Lozano-Calderón SA, 2016, J SURG ONCOL, V113, P811, DOI 10.1002/jso.24234
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   O'Sullivan B, 2002, LANCET, V359, P2235, DOI 10.1016/S0140-6736(02)09292-9
   O'Sullivan B, 2013, CANCER-AM CANCER SOC, V119, P1878, DOI 10.1002/cncr.27951
   Santosa KB, 2019, J SURG RES, V235, P560, DOI 10.1016/j.jss.2018.10.043
   seer.ims.nci.nih, 1975, Cancer incidence and survival among children and adolescents: United States SEER program
   Shields DW, 2021, BONE JOINT OPEN, V2, P1049, DOI 10.1302/2633-1462.212.BJO-2021-0103.R1
   Spunt SL, 2020, LANCET ONCOL, V21, P145, DOI 10.1016/S1470-2045(19)30672-2
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Tseng JF, 2006, ANN SURG ONCOL, V13, P1209, DOI 10.1245/s10434-006-9028-6
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Womer RB, 2012, J CLIN ONCOL, V30, P4148, DOI 10.1200/JCO.2011.41.5703
NR 32
TC 4
Z9 6
U1 0
U2 1
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0022-3468
EI 1531-5037
J9 J PEDIATR SURG
JI J. Pediatr. Surg.
PD SEP
PY 2024
VL 59
IS 9
BP 1735
EP 1739
DI 10.1016/j.jpedsurg.2024.02.028
EA AUG 2024
PG 5
WC Pediatrics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA C7S7B
UT WOS:001291338100001
PM 38548494
DA 2026-07-24
ER

PT J
AU Guerra, O
   Maclin, MM
AF Guerra, O.
   Maclin, M. M.
TI Non-crosslinked porcine-derived acellular dermal matrix for the
   management of complex ventral abdominal wall hernias: a report of 45
   cases
SO HERNIA
LA English
DT Article
DE Ventral abdominal wall hernias; Non-crosslinked intact porcine-derived
   acellular dermal matrix; Vacuum-assisted closure; Synthetic mesh;
   Biologic acellular dermal matrix; Strattice
ID TERM-FOLLOW-UP; INCISIONAL HERNIA; COMPONENT SEPARATION; REPAIR;
   RECONSTRUCTION; OUTCOMES; LAPAROTOMY
AB Ventral abdominal wall hernias are common and repair is frequently associated with complications and recurrence. Although non-crosslinked intact porcine-derived acellular dermal matrix (PADM) has been used successfully in the repair of complex ventral hernias, there is currently no consensus regarding the type of mesh and surgical techniques to use in these patients. This report provides added support for PADM use in complex ventral hernias.
   In a consecutive series of adult patients (2008-2011), complex ventral abdominal wall hernias (primary and incisional) were repaired with PADM by a single surgeon. Patient comorbidities, repair procedures, and postoperative recovery, recurrence, and complications were noted.
   Forty-four patients (mean age, 57.5 years) underwent 45 single-stage ventral abdominal wall hernia repairs (3 primary; 42 incisional). Previously placed synthetic mesh was removed in 17 cases. In 40 cases, primary fascial closure was achieved; in 5 cases, PADM was used as a bridge. Vacuum-assisted closure (VAC) was used for 38/45 cases: 19 closed incisions, 16 cases using the "French fry" technique, and 3 cases with open incisions. Mean hospital stay was 8.2 days (range, 3-32) and mean follow-up was 17 months (range, 1-48). There were 4 (8.9 %) hernia recurrences, 3 requiring additional repair and 1 requiring PADM explantation. There were 3 (6.7 %) skin dehiscences, 4 (8.9 %) deep wound infections requiring drainage, and 5 (11.1 %) seromas (4 self-limited, 1 requiring drainage).
   Non-crosslinked intact PADM yielded favorable early outcomes when used to repair complex ventral abdominal wall hernias in high-risk patients.
C1 [Guerra, O.] Suburban Surg Associates, St Louis, MO 63141 USA.
   [Maclin, M. M.] Parkcrest Plast Surg, St Louis, MO USA.
RP Guerra, O (通讯作者)，Suburban Surg Associates, 555 N New Ballas Rd,Ste 265, St Louis, MO 63141 USA.
EM omarg@ssainc.net
FU LifeCell Corp., Branchburg, NJ
FX This was an Institutional Review Board-approved retrospective cohort
   study. Editorial support for this article was provided by Peloton
   Advantage, LLC, Parsippany, NJ, and funded by LifeCell Corp.,
   Branchburg, NJ. Dr. Guerra is a consultant for LifeCell Corp. and KCI.
   Dr. Maclin is a consultant for KCI, LifeCell Corp. and Cook Medical.
CR [Anonymous], ANN PLAST SURG
   Brenner M, 2011, ARCH SURG-CHICAGO, V146, P395, DOI 10.1001/archsurg.2010.284
   Breuing K, 2010, SURGERY, V148, P544, DOI 10.1016/j.surg.2010.01.008
   Butler CE, 2011, PLAST RECONSTR SURG, V128, P698, DOI 10.1097/PRS.0b013e318221dcce
   Byrd JF, 2011, ANN M AM ASS PLAST S
   Campbell KT, 2011, PLAST RECONSTR SURG, V127, P2321, DOI 10.1097/PRS.0b013e318213a053
   Conde-Green A, 2012, ANN PLAST SURG
   Eid GM, 2003, SURGERY, V134, P599, DOI 10.1016/S0039-6060(03)00283-6
   Franklin ME, 2008, SURG ENDOSC, V22, P1941, DOI 10.1007/s00464-008-0005-y
   Gassman A, 2012, J AM COLL SURGEONS, V215, pS109, DOI 10.1016/j.jamcollsurg.2012.06.288
   Israelsson LA, 1996, EUR J SURG, V162, P125
   Itani KMF, 2012, SURGERY, V152, P498, DOI 10.1016/j.surg.2012.04.008
   Katerinaki E, 2010, J PLAST RECONSTR AES, V63, pE840, DOI 10.1016/j.bjps.2010.06.033
   Luijendijk RW, 2000, NEW ENGL J MED, V343, P392, DOI 10.1056/NEJM200008103430603
   Maurice SM, 2009, AM J SURG, V197, P35, DOI 10.1016/j.amjsurg.2007.11.019
   MUDGE M, 1985, BRIT J SURG, V72, P70, DOI 10.1002/bjs.1800720127
   Patel KM, 2012, ANN PLAS SURG, V69, P394, DOI 10.1097/SAP.0b013e31822f997b
   READ RC, 1989, ARCH SURG-CHICAGO, V124, P485
   Stromberg J, 2010, PLAST RECONSTR SURG, V125, P106
   Van T Riet M, 2004, AM SURGEON, V70, P281
   Zhong T, 2011, J PLAST RECONSTR AES, V64, P1562, DOI 10.1016/j.bjps.2011.04.035
NR 21
TC 13
Z9 14
U1 0
U2 8
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1265-4906
EI 1248-9204
J9 HERNIA
JI Hernia
PD FEB
PY 2014
VL 18
IS 1
BP 71
EP 79
DI 10.1007/s10029-013-1148-x
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 304BK
UT WOS:000330720000009
PM 23934355
OA hybrid
DA 2026-07-24
ER

PT J
AU Marangi, GF
   Mirra, C
   Gratteri, M
   Cogliandro, A
   Salzillo, R
   Segreto, F
   Federico, G
   Romano, FD
   Rossi, C
   Persichetti, P
AF Marangi, Giovanni Francesco
   Mirra, Carlo
   Gratteri, Marco
   Cogliandro, Annalisa
   Salzillo, Rosa
   Segreto, Francesco
   Federico, Gaetano
   Romano, Fara Desiree
   Rossi, Caterina
   Persichetti, Paolo
TI Switching from Galenic to Advanced Dressings or Vacuum Assisted Closure
   Therapy Can Improve Quality of Life of Patients with Chronic
   Non-Responsive Pressure Skin Ulcers: Preliminary Data with Italian
   Translation of WOUND-Q
SO ADVANCES IN WOUND CARE
LA English
DT Article
DE chronic wounds; dressings; negative pressure; personalized health care
ID VALIDATION; DEFINITION
AB Objective: A few studies have focused on the quality of life (QoL) of patients with chronic non-responsive pressure skin ulcers. The aim of this study was to assess how correct treatment (advanced wound care [AWC] dressings alone or vacuum assisted closure [VAC] therapy alone) changes the QoL of these patients.
   Approach: One hundred six patients with chronic non-responsive pressure skin ulcers, who had previously used galenic dressings, applied without proper therapeutic indication, were included in this study. We administered the WOUND-Q, at time 0 and after 1 month of appropriate therapy, to assess patient-reported outcome measures. Group 1 consisted of 30 patients treated with advanced dressings, Group 2: 22 patients treated with VAC therapy, and Group 3: 30 patients continuing conventional galenic dressings (Control group). Statistical analysis allowed us to analyze QoL changes over time and to compare WOUND-Q Group 1 and 2 deltas with those of Group 3. The study followed the STROBE statement.
   Results and Innovation: In all the scales evaluated (Assessment, Drainage, Smell, Life impact, Psychological, Social, Sleep and Dressing), there were significant improvements in mean values for Groups 1 and 2. Kruskal-Wallis tests with Dunn's multiple-comparisons tests and Brown-Forsythe and Welch Analysis of Variance tests demonstrated significant differences between deltas of Group 1 and Group 2 compared with those of Group 3 for most scales analyzed.
   Conclusions: Administration of the WOUND-Q demonstrated that the application of advanced dressings alone or VAC therapy alone positively affects the QoL of patients with chronic nonresponsive pressure wounds, in comparison with galenic dressings alone. The WOUND-Q has been shown to be a valid tool in studying changes in QoL of these patients.
C1 [Marangi, Giovanni Francesco; Mirra, Carlo; Gratteri, Marco; Cogliandro, Annalisa; Salzillo, Rosa; Segreto, Francesco; Federico, Gaetano; Romano, Fara Desiree; Rossi, Caterina; Persichetti, Paolo] Campus Biomed Univ Hosp, Dept Plast Reconstruct & Aesthet Surg, I-00128 Rome, Italy.
C3 Fondazione Policlinico Universitario Campus Bio-Medico; University
   Campus Bio-Medico - Rome Italy
RP Gratteri, M (通讯作者)，Campus Biomed Univ Hosp, Dept Plast Reconstruct & Aesthet Surg, I-00128 Rome, Italy.
EM m.gratteri@unicampus.it
RI , Annalisa/ADW-5837-2022; Marangi, Giovanni/AAW-4723-2020; Salzillo,
   Rosa/HJB-3151-2022; Gratteri, Marco/KGM-5481-2024
OI Gratteri, Marco/0000-0001-7375-1524; Rossi, Caterina/0000-0001-9223-6413
CR aiuc, REPORT E ANALISI DEI DATI-Aiuc-Associazione Italiana Ulcere Cutanee Onlus
   Akushevich I, 2013, EXP GERONTOL, V48, P1395, DOI 10.1016/j.exger.2013.09.005
   Augustin M., 2014, Wound Medicine, V5, P4, DOI DOI 10.1016/J.WNDM.2014.04.001
   Augustin M., 2014, Wound Med, V5, P29, DOI DOI 10.1016/J.WNDM.2014.04.008
   Augustin M, 2012, CURR DERMATOL REP, V1, P148, DOI 10.1007/s13671-012-0020-z
   Azmat CE, 2022, Wound closure techniques. StatPearls
   Bland JM, 2015, BMC CARDIOVASC DISOR, V15, DOI 10.1186/s12872-015-0080-7
   Braza ME, 2022, Wound Dressings
   Britto EJ, 2022, StatPearls
   Brown A, 2014, INT WOUND J, V11, P326, DOI 10.1111/iwj.12199
   Montero EC, 2021, ACTAS DERMO-SIFILOGR, V112, P44, DOI 10.1016/j.ad.2020.09.007
   Cutting Keith F, 2004, Br J Community Nurs, V9, pS6
   Daar AS, 2007, J TISSUE ENG REGEN M, V1, P179, DOI 10.1002/term.20
   Deshpande Prasanna R, 2011, Perspect Clin Res, V2, P137, DOI 10.4103/2229-3485.86879
   Fujimoto M, 2020, J DERMATOL, V47, P1071, DOI 10.1111/1346-8138.15186
   GNEAUPP, Quick reference-guide-digital-npuapepuap-pppia-jan2016
   Hareendran A, 2007, WOUND REPAIR REGEN, V15, P465, DOI 10.1111/j.1524-475X.2007.00253.x
   Herber OR, 2007, HEALTH QUAL LIFE OUT, V5, DOI 10.1186/1477-7525-5-44
   Hyland M E, 1994, J Wound Care, V3, P294
   Järbrink K, 2016, SYST REV-LONDON, V5, DOI 10.1186/s13643-016-0329-y
   Kangal M.K.O., 2022, Wound Healing
   Kisala PA, 2015, J SPINAL CORD MED, V38, P303, DOI 10.1179/2045772315Y.0000000017
   Klassen A, 2020, BMJ OPEN, V10, DOI 10.1136/bmjopen-2019-032332
   Klassen AF, 2021, INT WOUND J, V18, P487, DOI 10.1111/iwj.13549
   Markova A, 2012, DERMATOL CLIN, V30, P107, DOI 10.1016/j.det.2011.08.005
   McClimans L, 2017, STUD HIST PHILOS SCI, V65-66, P67, DOI 10.1016/j.shpsa.2017.06.004
   Mervis JS, 2019, J AM ACAD DERMATOL, V81, P881, DOI 10.1016/j.jaad.2018.12.069
   Naderi N, 2017, INT WOUND J, V14, P112, DOI 10.1111/iwj.12569
   nice.org, Overview j Leg ulcer infection: Antimicrobial prescribing j Guidance j NICE
   O'Rourke Maureen E, 2006, Clin J Oncol Nurs, V10, P825
   Palfreyman Simon, 2007, Nurs Stand, V21, P57
   Rahman GA, 2010, ANN AFR MED, V9, P1, DOI 10.4103/1596-3519.62615
   Segreto F, 2020, INT WOUND J, V17, P1702, DOI 10.1111/iwj.13454
   Segreto F, 2020, ARCH PLAST SURG-APS, V47, P217, DOI 10.5999/aps.2019.01571
   Smith JJ, 2000, J VASC SURG, V31, P642, DOI 10.1067/mva.2000.104103
   Sommer R, 2018, WOUND REPAIR REGEN, V26, P293, DOI 10.1111/wrr.12662
   Squitieri L, 2020, INT WOUND J, V17, P1052, DOI 10.1111/iwj.13374
   The World Health Organization Quality of Life (WHOQOL), About Us
   Tolbert E, 2018, MED DECIS MAKING, V38, P994, DOI 10.1177/0272989X18791177
   van Alphen TC, 2019, EUR J PLAST SURG, V42, P495, DOI 10.1007/s00238-019-01529-7
   Vileikyte L, 2003, DIABETES CARE, V26, P2549, DOI 10.2337/diacare.26.9.2549
   WOUND-Q-USERS-GUIDE.pdf, about us
   US
NR 43
TC 4
Z9 4
U1 0
U2 5
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD MAR 1
PY 2024
VL 13
IS 3
BP 131
EP 139
DI 10.1089/wound.2022.0150
PG 9
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA MT1T7
UT WOS:001195802000001
PM 37551983
DA 2026-07-24
ER

PT J
AU Bee, TK
   Croce, MA
   Magnotti, LJ
   Zarzaur, BL
   Maish, GO
   Minard, G
   Schroeppel, TJ
   Fabian, TC
AF Bee, Tiffany K.
   Croce, Martin A.
   Magnotti, Louis J.
   Zarzaur, Ben L.
   Maish, George O., III
   Minard, Gayle
   Schroeppel, Thomas J.
   Fabian, Timothy C.
TI Temporary abdominal closure techniques: A prospective randomized trial
   comparing polyglactin 910 mesh and vacuum-assisted closure
SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
LA English
DT Article; Proceedings Paper
CT 66th Annual Meeting of the
   American-Association-for-the-Surgery-of-Trauma
CY SEP 27-29, 2007
CL Las Vegas, NV
SP Amer Assoc Surg Trauma
ID COMPARTMENT SYNDROME; OPEN ABDOMEN; PACK; MESH
AB Objective: The options for abdominal coverage after damage control laparotomy or abdominal compartment syndrome vary by institution, surgeon preference, and type of patient. Some advocate polyglactin mesh (MESH), while others favor vacuum-assisted closure (VAC). We performed a single institution prospective randomized trial comparing morbidity and mortality differences between MESH and VAC.
   Methods: Patients expected to survive and requiring open abdomen management were prospectively randomized to either MESH or VAC. After randomization, an enteral feeding tube was inserted and the closure device placed. VAC patients returned to the operating room every 3 days for a total of three changes at which time polyglactin mesh was placed if closure was not possible. The MESH group had twice daily assessments for the possibility of bedside mesh cinching and closure. Both groups underwent split thickness skin grafting when granulation tissue was evident, if delayed primary closure was not possible.
   Results: Fifty-one patients were randomized. Both cohorts were matched for Injury Severity Scale score, gender, blunt/penetrating/abdominal compartment syndrome and age. Three patients died within 7 days and were excluded from closure rate calculation. There were no differences between delayed primary fascial closure rates in the VAC (31%) or MESH (26%) groups. The fistula rate in the VAC group was 21 % but not statistically different from the 5% rate for MESH. Intraabdominal rates were not statistically different. All VAC fistulas were related to feeding tubes and suture line areas; the MESH fistula followed a retroperitoneal colon leak remote from the mesh.
   Conclusions: MESH and VAC are both useful methods for abdominal coverage, and are equally likely to produce delayed primary closure. The fistula rate for VAC is most likely due to continued bowel manipulation with VAC changes with a feeding tube in place-enteral feeds should be administered via nasojejunal tube. Neither method precludes secondary abdominal wall reconstruction.
C1 [Bee, Tiffany K.; Croce, Martin A.; Magnotti, Louis J.; Zarzaur, Ben L.; Maish, George O., III; Minard, Gayle; Schroeppel, Thomas J.; Fabian, Timothy C.] Univ Tennessee, Hlth Sci Ctr, Dept Surg, Memphis, TN 38163 USA.
C3 University of Tennessee System; University of Tennessee Health Science
   Center
RP Bee, TK (通讯作者)，Univ Tennessee, Hlth Sci Ctr, Dept Surg, 956 Court Ave,C208, Memphis, TN 38163 USA.
EM tbee@utmem.edu
RI ; Zarzaur, Ben/S-6572-2019
OI Schroeppel, Thomas/0000-0001-9164-5004; Zarzaur, Ben/0000-0001-9988-9572
CR Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   BROCK WB, 1995, AM SURGEON, V61, P30
   Ciresi DL, 1999, AM SURGEON, V65, P720
   FABIAN TC, 1994, ANN SURG, V219, P651
   Meldrum DR, 1997, AM J SURG, V174, P667, DOI 10.1016/S0002-9610(97)00201-8
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   SCHEIN M, 1995, J AM COLL SURGEONS, V180, P745
   Scott BG, 2006, J TRAUMA, V60, P17, DOI 10.1097/01.ta.0000200861.96568.bb
   Sherck J, 1998, AM SURGEON, V64, P854
   VOYLES CR, 1981, ANN SURG, V194, P219, DOI 10.1097/00000658-198108000-00017
NR 10
TC 158
Z9 176
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0022-5282
J9 J TRAUMA
JI J. Trauma-Injury Infect. Crit. Care
PD AUG
PY 2008
VL 65
IS 2
BP 337
EP 342
DI 10.1097/TA.0b013e31817fa451
PG 6
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC General & Internal Medicine; Surgery
GA 337US
UT WOS:000258461600019
PM 18695468
DA 2026-07-24
ER

PT J
AU Fuchs, U
   Zittermann, A
   Stuettgen, B
   Groening, A
   Minami, K
   Koerfer, R
AF Fuchs, U
   Zittermann, A
   Stuettgen, B
   Groening, A
   Minami, K
   Koerfer, R
TI Clinical outcome of patients with deep sternal wound infection managed
   by vacuum-assisted closure compared to conventional therapy with open
   packing: A retrospective analysis
SO ANNALS OF THORACIC SURGERY
LA English
DT Article
ID PRESSURE SUCTION DRAINAGE; POSTSTERNOTOMY MEDIASTINITIS;
   CARDIAC-SURGERY; STERNOTOMY
AB Background. It is suggested that the vacuum technique is a promising new method for the therapy of mediastinitis, but reliable investigations are currently almost completely lacking. We therefore compared clinical outcome of patients whose sternal infection was managed with the vacuum-assisted closure system or with the conventional procedure of open packing.
   Methods. We performed a retrospective analysis in 68 cases of sternal wound infection that were identified at our Heart Center between September 1998 and September 2003. Thirty-five patients could be allocated to the vacuum group and 33 patients to the conventional group. We compared the time interval from sternal infection until freedom of microbiological cultures, in-hospital stay, the status at discharge (rewired or open sternum), the time interval until wound healing was achieved, and survival rates. Moreover, we compared serum levels of C-reactive protein and blood leukocyte counts on admission, at diagnosis of sternal infection, and at different points of time until discharge.
   Results. Baseline characteristics and blood factors did not differ between the two study groups at diagnosis of sternal infection. Moreover, the number of prescribed antibiotics was similar, and the C-reactive protein level and blood leukocyte counts at discharge were comparable in both groups. However, freedom from mediastinal microbiological cultures was achieved earlier (p < 0.01), C-reactive protein levels declined more rapidly (p < 0.025), in-hospital stay was shorter (p < 0.01), rewiring was earlier (p < 0.01), and survival tended to be higher (p < 0.15) in the vacuum group compared to the conventional group.
   Conclusions. This retrospective analysis could demonstrate that the vacuum technique improves the medical outcome of patients with mediastinitis compared with the conventional technique of open packing. (C) 2005 by The Society of Thoracic Surgeons.
C1 Ruhr Univ Bochum, Heart Ctr N Rhine Westfalia, Dept Cardiovasc Surg, D-32545 Bad Oeynhausen, Germany.
   Ruhr Univ Bochum, Heart Ctr N Rhine Westfalia, Dept Lab & Transfus Med, D-32545 Bad Oeynhausen, Germany.
C3 Ruhr University Bochum; Ruhr University Bochum
RP Fuchs, U (通讯作者)，Ruhr Univ Bochum, Heart Ctr N Rhine Westfalia, Dept Cardiovasc Surg, Georgstr 11, D-32545 Bad Oeynhausen, Germany.
EM ufuchs@hdz-nrw.de
CR Abu-Omar Y, 2003, ANN THORAC SURG, V76, P974, DOI 10.1016/S0003-4975(03)00180-2
   Baskett RJF, 1999, ANN THORAC SURG, V67, P462, DOI 10.1016/S0003-4975(98)01195-3
   Catarino PA, 2000, ANN THORAC SURG, V70, P1891, DOI 10.1016/S0003-4975(00)02173-1
   De Feo M, 2001, ANN THORAC SURG, V71, P324, DOI 10.1016/S0003-4975(00)02137-8
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Fleck TM, 2004, ANN PLAS SURG, V52, P310, DOI 10.1097/01.sap.0000105524.75597.e0
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Fleck TM, 2003, ANN THORAC SURG, V76, P974, DOI 10.1016/S0003-4975(03)00189-9
   Francel TJ, 2001, ANN THORAC SURG, V72, P1419, DOI 10.1016/S0003-4975(00)02009-9
   GARNER JS, 1988, AM J INFECT CONTROL, V16, P128, DOI 10.1016/0196-6553(88)90053-3
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
   Hersh RE, 2001, HEART SURG FORUM, V4, P211
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   KAPLAN EL, 1958, J AM STAT ASSOC, V53, P457, DOI 10.2307/2281868
   LOOP FD, 1990, ANN THORAC SURG, V49, P179, DOI 10.1016/0003-4975(90)90136-T
   Luckraz H, 2003, J THORAC CARDIOV SUR, V125, P301, DOI 10.1067/mtc.2003.74
   Schumaker Jr H.B., 1963, ARCH SURG-CHICAGO, V86, P384
NR 18
TC 102
Z9 122
U1 0
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD FEB
PY 2005
VL 79
IS 2
BP 526
EP 531
DI 10.1016/j.athoracsur.2004.08.032
PG 6
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 895GY
UT WOS:000226850200023
PM 15680828
DA 2026-07-24
ER

PT J
AU Perez, D
   Wildi, S
   Demartines, N
   Bramkamp, M
   Koehler, C
   Clavien, PA
AF Perez, Daniel
   Wildi, Stefan
   Demartines, Nicolas
   Bramkamp, Matthias
   Koehler, Christian
   Clavien, Pierre-Alain
TI Prospective evaluation of vacuum-assisted closure in abdominal
   compartment syndrome and severe abdominal sepsis
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Article
AB Background: Open abdomen treatment because of severe abdominal sepsis and abdominal compartment syndrome remains a difficult task. Different surgical techniques are available and are often used according to the surgeon's personal experience. Recently, the abdominal vacuum-assisted closure (VAC) system has been introduced, providing a new possibility to treat an open abdomen. In this study, we evaluate the role of this treatment option.
   Study design: This prospective observational cohort study includes 37 consecutive patients who were temporarily treated with VAC for severe abdominal sepsis or abdominal compartment syndrome, or both. Patients with abdominal trauma were excluded from the study. Thirty-seven patients undergoing major elective laparotomy and primary abdominal closure served as control group. Primary end points were fascial closure rate, physicoemotional recovery, and appearance outcomes 1 year after closure. Secondary end points included mortality, duration of open abdomen, length of ICU stay, and hospitalization time.
   Results: Abdomens were left open for 23 days (range 3 to 122 days) with 3.8 dressing changes (range 1 to 22) per patient. Abdominal closure was achieved in 70% (n = 26), with no marked relation to duration of open abdomen treatment (p > 0.05). After 3 months, patients with VAC treatment recovered to a physical and mental health status similar to patients in the control group (p > 0.05). This status remained stable until the end of the study. Aesthetic outcomes (according to the Vancouver Scar Scale) were considerably poorer in the VAC group compared with controls (p < 0.01).
   Conclusions: Treatment of laparostomy with VAC for abdominal sepsis and abdominal compartment syndrome results in a high rate of successful abdominal closure. In addition, patients recover more rapidly, although hypertrophic scars might interfere with body perception. We recommend abdominal VAC system as first option if open abdomen treatment is indicated.
C1 Univ Zurich Hosp, Dept Visceral & Transplantat Surg, CH-8091 Zurich, Switzerland.
   Univ Zurich Hosp, Dept Internal Med, CH-8091 Zurich, Switzerland.
   Univ Zurich Hosp, Dept Plast & Reconstruct Surg, CH-8091 Zurich, Switzerland.
   Univ Lausanne Hosp, Dept Visceral Surg, Lausanne, Switzerland.
C3 University of Zurich; University Zurich Hospital; University of Zurich;
   University Zurich Hospital; University of Zurich; University Zurich
   Hospital; University of Lausanne; Centre Hospitalier Universitaire
   Vaudois (CHUV)
RP Clavien, PA (通讯作者)，Univ Zurich Hosp, Dept Visceral & Transplantat Surg, Raemistr 100, CH-8091 Zurich, Switzerland.
EM clavien@chir.unizh.ch
OI Perez, Daniel/0000-0002-3154-7311; Demartines,
   Nicolas/0000-0002-1530-3114
CR Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Bauer JJ, 1999, MT SINAI J MED, V66, P20
   BROCK WB, 1995, AM SURGEON, V61, P30
   BULLINGER M, 1995, SOC SCI MED, V41, P1359, DOI 10.1016/0277-9536(95)00115-N
   Cense HA, 2004, J SURG ONCOL, V88, P32, DOI 10.1002/jso.20132
   Cipolla J, 2005, AM SURGEON, V71, P202
   Ciresi DL, 1999, AM SURGEON, V65, P720
   CIRESI DL, 1999, AM SURGEON, V8, P724
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   Deysine M, 1998, SURG CLIN N AM, V78, P1105, DOI 10.1016/S0039-6109(05)70372-8
   Erdmann D, 2001, PLAST RECONSTR SURG, V108, P2066, DOI 10.1097/00006534-200112000-00036
   FABIAN TC, 1994, ANN SURG, V219, P643, DOI 10.1097/00000658-199406000-00007
   FELICIANO DV, 1988, ANN SURG, V208, P362, DOI 10.1097/00000658-198809000-00014
   Fernandez L, 1996, J TRAUMA, V40, P258, DOI 10.1097/00005373-199602000-00014
   Garner GB, 2001, AM J SURG, V182, P630, DOI 10.1016/S0002-9610(01)00786-3
   Gayle WE, 1997, AM SURGEON, V63, P1107
   GRACIAS VH, 2002, ARCH SURG-CHICAGO, V11, P1298
   Howdieshell TR, 2004, AM J SURG, V188, P301, DOI 10.1016/j.amjsurg.2004.03.007
   LINDER MM, 1987, CHIRURG, V58, P84
   Mayberry JC, 2004, J TRAUMA, V57, P157, DOI 10.1097/01.TA.0000102411.69521.80
   MAYBERRY JC, 1997, ARCH SURG-CHICAGO, V9, P957
   MCHORNEY CA, 1993, MED CARE, V31, P247, DOI 10.1097/00005650-199303000-00006
   Medeiros AC, 2004, DIGEST SURG, V21, P401, DOI 10.1159/000082317
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   MILLER PR, 2004, ANN SURG, V5, P614
   Moore AFK, 2004, BJS-BRIT J SURG, V91, P1102, DOI 10.1002/bjs.4703
   Nagy KK, 1996, AM SURGEON, V62, P331
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   QUINN JV, 1995, AM J EMERG MED, V13, P229, DOI 10.1016/0735-6757(95)90100-0
   Rattray JE, 2005, ANAESTHESIA, V60, P1085, DOI 10.1111/j.1365-2044.2005.04336.x
   SMITH IE, 1995, BRIT J ANAESTH, V75, P399, DOI 10.1093/bja/75.4.399
   Smith LA, 1997, AM SURGEON, V63, P1102
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   SULLIVAN T, 1990, Journal of Burn Care and Rehabilitation, V11, P256, DOI 10.1097/00004630-199005000-00014
   Tsuei BJ, 2004, AM SURGEON, V70, P652
   Vincent JL, 1998, CRIT CARE MED, V26, P1793, DOI 10.1097/00003246-199811000-00016
NR 36
TC 148
Z9 164
U1 0
U2 8
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1072-7515
EI 1879-1190
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD OCT
PY 2007
VL 205
IS 4
BP 586
EP 592
DI 10.1016/j.jamcollsurg.2007.05.015
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 222QP
UT WOS:000250312300010
PM 17903734
DA 2026-07-24
ER

PT J
AU Jacobs, S
   Simhaee, DA
   Marsano, A
   Fomovsky, GM
   Niedt, G
   Wu, JK
AF Jacobs, Sharone'
   Simhaee, David A.
   Marsano, Anna
   Fomovsky, Gregory M.
   Niedt, George
   Wu, June K.
TI Efficacy and mechanisms of vacuum-assisted closure (VAC) therapy in
   promoting wound healing: a rodent model
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article; Proceedings Paper
CT 20th Annual Symposium on Advanced Wound Care
CY APR 28-MAY 01, 2007
CL Tampa, FL
DE VAC device; Rat model; Wound healing; Angiogenesis
ID MICROVESSEL DENSITY; ANGIOGENESIS; PRESSURE; TUMORS
AB Background: The vacuum-assisted closure device (VAC) has revolutionised wound care, although molecular mechanisms are not well understood. We hypothesise that the VAC device induces production of pro-angiogenic factors and promotes formation of granulation tissue and healing.
   Methods: A novel rodent model of VAC wound healing was established. Excisional wounds were created on rat dorsa. Wounds were dressed with Tegaderm (control group), VAC Granulofoam (R) and Tegaderm(special control group), or VAC Granulofoam (R), T. R. A. C. PAD (R) with 125 mm Hg continuous negative pressure (VAC group). Wound closure rates were calculated as a percentage of initial wound sizes. Rats were sacrificed on postoperative days 3, 5 and 7; harvested tissues were processed for histology [haematoxylin & eosin (H&E), Masson's trichrome, picrosirius red] and Western blot analysis (CD31, vascular endothelial growth factor, basic fibroblast growth factor).
   Results: Statistically significant wound closure rates were achieved in the experimental group at all measured time points: day 3, 28.1% (VAC) vs 8.2% (control) and 8.8% (special control) (ANOVA, P < 0.0001); day 5, 45.3% ( VAC) vs 23.7% (control) and 22.5% ( special control) (ANOVA, P = 0.0003); day 7, 54.4% (VAC) vs 43.0% (control) and 31.5% (special control) (ANOVA; P < 0.0001). Morphological evaluation by Masson's trichrome stain showed increased collagen organisation and wound maturation in the VAC group. These wounds also showed increased expression of vascular endothelial growth factor and fibroblast growth factor-2 on day 5 by Western blot analysis.
   Conclusion: A small animal VAC wound model was established. Wounds treated with a VAC device showed accelerated wound closure rates, increased pro-angiogenic growth factor production and improved collagen deposition. Further application of this model may elucidate other mechanisms. (C) 2008 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Jacobs, Sharone'; Simhaee, David A.; Wu, June K.] Columbia Univ, Coll Phys & Surg, Div Plast & Reconstruct Surg, New York, NY USA.
   [Marsano, Anna; Fomovsky, Gregory M.] Columbia Univ, Coll Phys & Surg, Dept Biomed Engn, New York, NY USA.
   [Niedt, George] Columbia Univ, Coll Phys & Surg, Dept Dermatol, New York, NY USA.
C3 Columbia University; Columbia University; Columbia University
RP Wu, JK (通讯作者)，161 Ft Washington Ave,Suite 601, New York, NY 10032 USA.
EM jw92@columbia.edu
OI Marsano, Anna/0000-0002-3084-0823
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong David G, 2002, Ostomy Wound Manage, V48, P64
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Fabian TS, 2000, AM SURGEON, V66, P1136
   FROHLICH MW, 1986, STAIN TECHNOL, V61, P139, DOI 10.3109/10520298609110723
   Frykberg R G, 2000, J Foot Ankle Surg, V39, pS1
   Galiano RD, 2004, AM J PATHOL, V164, P1935, DOI 10.1016/S0002-9440(10)63754-6
   Goddard JC, 2001, BJU INT, V87, P866, DOI 10.1046/j.1464-410x.2001.02181.x
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   Jones SM, 2005, POSTGRAD MED J, V81, P353, DOI 10.1136/pgmj.2004.026351
   LABLER L, 2006, ZENTRALBL CHIR, V1, pS62
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   McCallon S K, 2000, Ostomy Wound Manage, V46, P28
   Miller Quintessa, 2004, Curr Surg, V61, P205, DOI 10.1016/j.cursur.2003.07.015
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Saaristo A, 2006, AM J PATHOL, V169, P1080, DOI 10.2353/ajpath.2006.051251
   Samson D. J., 2004, AHRQ PUBLICATION
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Stadelmann WK, 1998, AM J SURG, V176, p26S, DOI 10.1016/S0002-9610(98)00183-4
   Valencia IC, 2001, J AM ACAD DERMATOL, V44, P401, DOI 10.1067/mjd.2001.111633
   WEIDNER N, 1995, BREAST CANCER RES TR, V36, P169, DOI 10.1007/BF00666038
   WHITTAKER P, 1994, BASIC RES CARDIOL, V89, P397, DOI 10.1007/BF00788278
NR 23
TC 88
Z9 106
U1 0
U2 13
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD OCT
PY 2009
VL 62
IS 10
BP 1331
EP 1338
DI 10.1016/j.bjps.2008.03.024
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 529NJ
UT WOS:000272523800020
PM 18617451
DA 2026-07-24
ER

PT J
AU Petzina, R
   Gustafsson, L
   Mokhtari, A
   Ingemansson, R
   Malmsjö, M
AF Petzina, Rainer
   Gustafsson, Lotta
   Mokhtari, Arash
   Ingemansson, Richard
   Malmsjo, Malin
TI Effect of vacuum-assisted closure on blood flow in the peristernal
   thoracic wall after internal mammary artery harvesting
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article
DE animal model; experimental surgery; mediastinal infection; vascular tone
   and reactivity; wound healing
ID WOUND CONTROL; MEDIASTINITIS; EXPERIENCE; INFECTION; THERAPY; STRESS;
   DEEP
AB Objective: Vacuum-assisted closure (VAC) is a recently introduced method for the treatment of poststernotomy mediastinitis. The aim was to examine the effects of VAC negative pressure on peristernal soft tissue, blood flow after internal mammary artery harvesting. Methods: Microvascular blood flow was measured using laser Doppler velocimetry in a porcine sternotomy wound model. The effect of VAC negative pressure on blood flow to the wound edge was investigated on the right side, where the internal mammary artery was intact, and on the left side, where the internal mammary artery had been removed. Results: Before removal of the left internal mammary artery, the blood flow was similar in the right and left peristernal wound edges, 2.5 cm from the edge (27 +/- 4 perfusion units (PU) on the right side and 32 +/- 3 PU on the left side, in muscle tissue). When the left internal mammary artery was surgically removed, the blood flow on the left side decreased (19 3 PU, in muscle tissue), while the skin blood flow was not affected. VAC negative pressure induced an immediate increase in wound edge blood flow both on the right side (43 +/- 9 PU, in muscle tissue at -75 mmHg), where the internal mammary artery was intact, and on the left side, where the internal mammary artery had been removed (49 11 PU, in muscle tissue at -75 mmHg). The increase in blood flow was similar on both sides at -75 mmHg and at -125 mmHg. Conclusions: The peristernal wound edge microvascular blood flow is decreased when the left internal mammary artery is removed. VAC therapy stimulates blood flow in the peristernal thoracic wall after internal mammary artery harvesting. (c) 2006 Elsevier B.V. All rights reserved.
C1 Univ Lund Hosp, Dept Med, S-22185 Lund, Sweden.
   Univ Lund Hosp, Dept Cardiothorac Surg, S-22185 Lund, Sweden.
C3 Lund University; Skane University Hospital; Lund University; Skane
   University Hospital
RP Malmsjö, M (通讯作者)，Lund Univ, BMC A13, SE-22184 Lund, Sweden.
EM malin.malmsjo@med.lu.se
OI Maljö, Malin/0000-0001-9849-9599; Gustafsson, Lotta/0000-0002-9826-9133;
   Ingemansson, Richard/0000-0001-7623-8953; Petzina,
   Rainer/0000-0002-0688-5482
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   CARRIER M, 1992, ANN THORAC SURG, V53, P115, DOI 10.1016/0003-4975(92)90768-Y
   Chen Shao-Zong, 2005, Asian J Surg, V28, P211, DOI 10.1016/S1015-9584(09)60346-8
   Clare MP, 2002, FOOT ANKLE INT, V23, P896, DOI 10.1177/107110070202301002
   Conquest AM, 2003, J SURG RES, V115, P209, DOI 10.1016/S0022-4804(03)00331-7
   DEJESUS RA, 1995, ANN THORAC SURG, V59, P163, DOI 10.1016/0003-4975(94)00722-J
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   Gummert JF, 2002, THORAC CARDIOV SURG, V50, P87, DOI 10.1055/s-2002-26691
   Gustafsson RI, 2003, ANN THORAC SURG, V76, P2048, DOI 10.1016/S0003-4975(03)01337-7
   KOLLER A, 1991, AM J PHYSIOL, V260, pH862, DOI 10.1152/ajpheart.1991.260.3.H862
   Miller Quintessa, 2004, Curr Surg, V61, P205, DOI 10.1016/j.cursur.2003.07.015
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Sjogren Johan, 2004, Interact Cardiovasc Thorac Surg, V3, P666, DOI 10.1016/j.icvts.2004.08.003
   Steinbrüchel DA, 2000, SCAND CARDIOVASC J, V34, P463, DOI 10.1080/140174300750064611
   Tang Su-yang, 2004, Zhonghua Zheng Xing Wai Ke Za Zhi, V20, P139
   URSCHEL JD, 1988, BRIT J PLAST SURG, V41, P182, DOI 10.1016/0007-1226(88)90049-5
   VANDENBURGH HH, 1992, AM J PHYSIOL, V262, pR350, DOI 10.1152/ajpregu.1992.262.3.R350
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
   Zacharias A, 1996, CHEST, V110, P1173, DOI 10.1378/chest.110.5.1173
   ZOGRAFOS GC, 1992, ANN SURG, V215, P266, DOI 10.1097/00000658-199203000-00011
NR 20
TC 66
Z9 88
U1 0
U2 3
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
EI 1873-734X
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD JUL
PY 2006
VL 30
IS 1
BP 85
EP 89
DI 10.1016/j.ejcts.2006.04.009
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 062GP
UT WOS:000238932900020
PM 16730446
DA 2026-07-24
ER

PT J
AU Gläsel, S
   Jarvers, JS
   Pieroh, P
   Heyde, CE
   Spiegl, UJ
AF Glaesel, Stefan
   Jarvers, Jan-Sven
   Pieroh, Philipp
   Heyde, Christoph-Eckhard
   Spiegl, Ulrich J.
TI Does the use of epicutaneous vacuum-assisted closure after revision
   surgery on the spine reduce further wound revision surgery?
SO INTERNATIONAL ORTHOPAEDICS
LA English
DT Article
DE Epicutaneous vacuum therapy; Surgical site infection; Wound revision
   surgery
ID PRESSURE; THERAPY; INFECTION; DEHISCENCE; FUSION
AB PurposeThis study aimed to investigate the effect of epicutaneous vacuum therapy on the rate of unplanned spinal wound revisions compared with conventional wound dressing.MethodsThis retrospective study included patients who underwent unplanned revision spine surgery after primary aseptic spine surgery who were treated at a level I spine centre between December 2011 and December 2019. Patients with revision surgery who required a further unplanned revision surgery during the inpatient stay were considered a treatment failure. The epicutaneous vacuum-assisted closure (Epi-VAC) therapy was the standard treatment method beginning in 2017 (the epi-VAC group). Before, conventional wound dressing was used (the control group (CG)). In addition, a one-to-one matched-pair comparison analysis was performed between both groups.ResultsOf 218 patients, 48 were in the epi-VAC group. The mean age was 65.1 years (epi-VAC 68.2 to CG 64.3 years (P = 0.085)), and the mean body mass index (BMI) was 28.2 kg/m(2) (epi-VAC 29.4 to CG 27.9 kg/m(2) (P = 0.16)). No significant differences in the treatment failure rate could be detected between the two groups (epi-VAC 25% to CG 22.4% (P = 0.7)). There was also no significant difference for the matched-pair analysis (epi-VAC 26.1% to CG 15.2% (P = 0.3)). An elevated CRP level (C-reactive protein) immediately before the first wound revision was a significant risk factor for further revision surgery (treatment failure: 135.2 +/- 128.6; no treatment failure: 79.7 +/- 86.1 mg/l (P < 0.05)).ConclusionConcerning repeat unplanned wound revision after spinal revision surgery, we cannot demonstrate an advantage of the epicutaneous vacuum therapy over conventional wound dressing.
C1 [Glaesel, Stefan] Sana Klinikum Borna, Dept Spine Surg & Neurotraumatol, Borna, Germany.
   [Jarvers, Jan-Sven; Pieroh, Philipp; Heyde, Christoph-Eckhard; Spiegl, Ulrich J.] Univ Leipzig, Dept Orthopaed Trauma Surg & Plast Surg, Liebigstr 20, D-04103 Leipzig, Germany.
C3 Leipzig University
RP Spiegl, UJ (通讯作者)，Univ Leipzig, Dept Orthopaed Trauma Surg & Plast Surg, Liebigstr 20, D-04103 Leipzig, Germany.
EM uli.spiegl@gmx.de
RI ; Heyde, Christoph - E./AAV-9440-2021
OI Spiegl, Ulrich/0000-0002-5179-4192; 
FU Projekt DEAL
FX Open Access funding enabled and organized by Projekt DEAL.
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   [Anonymous], 2018, BUNDESGESUNDHEITSBLA, V61, P448, DOI 10.1007/s00103-018-2706-2
   [Anonymous], TERM INCISIONAL
   [Anonymous], FILESREFERENZDATENOP
   Birke-Sorensen H, 2011, J PLAST RECONSTR AES, V64, pS1, DOI 10.1016/j.bjps.2011.06.001
   Borm W., 2017, WIRBELSAULE INTERDIS, P634
   Bowler PG, 2002, ANN MED, V34, P419, DOI 10.1080/078538902321012360
   Deng H, 2020, J NEUROSURG-SPINE, V32, P292, DOI 10.3171/2019.8.SPINE19479
   Dobran M, 2017, Surg Neurol Int, V8, P212, DOI [10.4103/sni.sni_222_17, 10.4103/sni.sni_222_17]
   du Prel JB, 2010, DTSCH ARZTEBL INT, V107, P343, DOI 10.3238/arztebl.2010.0343
   Dyck BA, 2019, J NEUROSURG-SPINE, V31, P430, DOI 10.3171/2019.2.SPINE18947
   Hachenberg T, 2010, ANAESTHESIST, V59, P851, DOI 10.1007/s00101-010-1789-4
   Hoeller S, 2021, EUR SPINE J, V30, P1261, DOI 10.1007/s00586-021-06782-8
   Malmsjö M, 2009, WOUND REPAIR REGEN, V17, P200, DOI 10.1111/j.1524-475X.2009.00461.x
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Naylor RM, 2020, WORLD NEUROSURG, V137, pE257, DOI 10.1016/j.wneu.2020.01.152
   Ogihara S, 2021, EUR SPINE J, V30, P1756, DOI 10.1007/s00586-020-06609-y
   Piper Keaton F, 2017, Surg Neurol Int, V8, P269, DOI [10.4103/sni.sni_306_17, 10.4103/sni.sni_306_17]
   Spiegl UJA., 2020, WHICH FACTORS INFLUE, P724, DOI [10.1007/s00113-020-00781-y, DOI 10.1007/S00113-020-00781-Y]
   Zhou JM, 2020, SPINE, V45, P208, DOI 10.1097/BRS.0000000000003218
NR 21
TC 2
Z9 2
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0341-2695
EI 1432-5195
J9 INT ORTHOP
JI Int. Orthop.
PD MAR
PY 2023
VL 47
IS 3
BP 803
EP 811
DI 10.1007/s00264-023-05695-z
EA JAN 2023
PG 9
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 9B4XQ
UT WOS:000920196500001
PM 36648534
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Strecker, T
   Rösch, J
   Horch, RE
   Weyand, M
   Kneser, U
AF Strecker, Thomas
   Roesch, Johannes
   Horch, Raymund E.
   Weyand, Michael
   Kneser, Ulrich
TI Sternal wound infections following cardiac surgery:: Risk factor
   analysis and interdisciplinary treatment
SO HEART SURGERY FORUM
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; RECTUS-ABDOMINIS MUSCLE; MYOCUTANEOUS
   ADVANCEMENT FLAPS; CHEST-WALL RECONSTRUCTION; SINGLE-STAGE MANAGEMENT;
   MUSCULOCUTANEOUS FLAPS; MEDIASTINAL INFECTION; DEFINITIVE CLOSURE;
   GREATER OMENTUM; HEART SURGERY
AB Objective. Sternal wound infections are a serious complication after cardiac surgery. Although a variety of treatment algorithms has been published, the ideal operative treatment of complicated median sternotomy wounds is the subject of ongoing controversy.
   Methods. In a retrospective review, 3016 consecutive open-heart surgery patients between January 2003 and June 2006 were evaluated: 65.6% underwent coronary artery bypass surgery (CABG), 16.3% cardiac valve replacement, 13.5% combined CABG and valve replacement, 2.8% aortic reconstruction or replacement, 0.6% artificial heart implantation, and 1.2% cardiac transplantation.
   Results. Sixty-three patients (2.1%) developed sternal wound infections. Fifty-six wounds were treated with debridement, irrigation, and re-wiring. Thirty-four patients were treated using vacuum-assisted closure therapy. Nineteen of these patients eventually required plastic surgical coverage with either rectus abdominis or pectoralis major flaps. Diabetes mellitus, rethoracotomy, duration of operation and, interestingly, the time of operation (morning versus afternoon) presented significant risk factors for development of sternal wound infections (P < .05). Three patients developed partial flap necrosis and required a second flap. Eventually, all defects were successfully reconstructed and there was no recurrent ostemyelitis noticed over the entire observation period (follow-up, 23 +/- 13 months).
   Discussion. Patients at risk for development of sternal wound infections may be preferably operated in the morning at first position. Vaccuum-assisted closure therapy acts as a link between radical debridement and definitive plastic coverage. The type of flap is individually chosen based on location of the defect and availability of certain vascular axis. The presented interdisciplinary approach with radical surgical debridement, application of subatmospheric pressure dressings, and early involvement of the plastic surgical team allows efficient treatment of infected median sternotomy wounds.
C1 Univ Erlangen Nurnberg, Ctr Cardiac Surg, D-91054 Erlangen, Germany.
   Univ Erlangen Nurnberg, Dept Plast & Hand Surg, Erlangen, Germany.
C3 University of Erlangen Nuremberg; University of Erlangen Nuremberg
RP Strecker, T (通讯作者)，Univ Erlangen Nurnberg, Ctr Cardiac Surg, Krankenhausstr 12, D-91054 Erlangen, Germany.
EM thomas.strecker@herz.imed.uni-erlangen.de
RI Horch, Raymund E/H-8128-2019
OI Horch, Raymund E/0000-0002-6561-2353
CR Agarwal JP, 2005, PLAST RECONSTR SURG, V116, P1035, DOI 10.1097/01.prs.0000178401.52143.32
   Ahumada LA, 2005, ANN PLAS SURG, V54, P264, DOI 10.1097/01.sap.0000153096.12780.19
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Ascherman JA, 2004, PLAST RECONSTR SURG, V114, P676, DOI 10.1097/01.PRS.0000130939.32238.3B
   BANIC A, 1995, ANN THORAC SURG, V60, P1028, DOI 10.1016/0003-4975(95)00428-N
   Baskett RJF, 1999, ANN THORAC SURG, V67, P462, DOI 10.1016/S0003-4975(98)01195-3
   Clarkson J, 2003, SCAND J PLAST RECONS, V37, P266, DOI 10.1080/02844310310000455
   COLEMAN JJ, 1989, SURG CLIN N AM, V69, P1007
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Farhat Fadi, 2004, Surg Technol Int, V13, P199
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   FLEISCHER A, 1993, ANN PLAS SURG, V31, P146, DOI 10.1097/00000637-199308000-00010
   Francel TJ, 2001, ANN THORAC SURG, V72, P1419, DOI 10.1016/S0003-4975(00)02009-9
   Fujiwara M, 2006, AESTHET PLAST SURG, V30, P120, DOI 10.1007/s00266-005-0145-6
   Gummert JF, 2002, THORAC CARDIOV SURG, V50, P87, DOI 10.1055/s-2002-26691
   HUGO NE, 1994, PLAST RECONSTR SURG, V93, P1433, DOI 10.1097/00006534-199406000-00016
   IACOBUCCI JJ, 1989, BRIT J PLAST SURG, V42, P452, DOI 10.1016/0007-1226(89)90013-1
   JEEVANANDAM V, 1990, J THORAC CARDIOV SUR, V99, P256
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   JULIAN OC, 1957, SURGERY, V42, P753
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   LEE AB, 1976, SURGERY, V80, P433
   López-Monjardin H, 1998, PLAST RECONSTR SURG, V101, P1481, DOI 10.1097/00006534-199805000-00008
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   MOON HK, 1988, PLAST RECONSTR SURG, V82, P815, DOI 10.1097/00006534-198811000-00014
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   NAHAI F, 1989, PLAST RECONSTR SURG, V84, P434, DOI 10.1097/00006534-198909000-00009
   Nashef SAM, 1999, EUR J CARDIO-THORAC, V16, P9, DOI 10.1016/S1010-7940(99)00134-7
   Oh AK, 2004, ANN PLAS SURG, V52, P367, DOI [10.1097/01.SAP.0000099710.38299.a3, 10.1097/01.sap.0000099710.38299.a3]
   PAIROLERO PC, 1991, ANN SURG, V213, P583, DOI 10.1097/00000658-199106000-00008
   SARR MG, 1984, ANN THORAC SURG, V38, P415, DOI 10.1016/S0003-4975(10)62300-4
   Scholl L, 2004, J CARDIAC SURG, V19, P453, DOI 10.1111/j.0886-0440.2004.05002.x
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Strecker T, 2006, J THORAC CARDIOV SUR, V132, P980, DOI 10.1016/j.jtcvs.2006.05.063
   WEINZWEIG N, 1995, ANN PLAS SURG, V34, P471, DOI 10.1097/00000637-199505000-00004
   Wong CHK, 2006, EUR J CARDIO-THORAC, V30, P148, DOI 10.1016/j.ejcts.2006.03.049
   YAMAMOTO Y, 1994, BRIT J PLAST SURG, V47, P103, DOI 10.1016/0007-1226(94)90167-8
NR 38
TC 38
Z9 42
U1 0
U2 3
PU FORUM MULTIMEDIA PUBLISHING, LLC
PI CHARLOTTESVILLE
PA 375 GREENBRIER DR, CHARLOTTESVILLE, VA 22901 USA
SN 1098-3511
EI 1522-6662
J9 HEART SURG FORUM
JI Heart Surg. Forum
PD OCT
PY 2007
VL 10
IS 5
BP E366
EP E371
DI 10.1532/HSF98.20071079
PG 6
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 236MW
UT WOS:000251308100004
PM 17855200
OA gold
DA 2026-07-24
ER

PT J
AU Ropski, MK
   Guillaumin, J
   Monnig, AA
   Townsend, K
   McLoughlin, MA
AF Ropski, Meaghan K.
   Guillaumin, Julien
   Monnig, Andrea A.
   Townsend, Katy
   McLoughlin, Mary A.
TI Use of cryopoor plasma for albumin replacement and continuous
   antimicrobial infusion for treatment of septic peritonitis in a dog
SO JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE
LA English
DT Article
DE canine; colloids; hydroxyethyl starch; sepsis
ID CRITICALLY-ILL PATIENTS; BETA-LACTAM ANTIBIOTICS; SEVERE SEPSIS; RENAL
   DYSFUNCTION; PHARMACOKINETICS; TRANSFUSION; IMIPENEM; EFFICACY; FLUID;
   RISK
AB Objective - To report the successful management of a dog with septic peritonitis and septic shock secondary to enterectomy dehiscence using novel techniques for identification of intestinal dehiscence and for septic shock treatment.
   Case Summary - A5-year-old castrated male Bernese Mountain Dog presented for lethargy 6 days following enterotomy for foreign body obstruction. Septic peritonitis was identified due to dehiscence of the enterotomy site, and resection and anastomosis were performed using a gastrointestinal anastomosis and thoracoabdominal stapling device. Postoperatively the patient experienced severe hypotension, which responded to norepinephrine constant rate infusion (CRI) after failing to improve with fluid therapy or dopamine CRI. Further treatment included antimicrobial CRI and supportive care including careful fluid therapy. Due to low effective circulating volume paired with intersititial fluid overload and large volume abdominal effusion, fluid therapy consisted of a combination of human serum albumin, canine albumin, synthetic colloids, and isotonic crystalloids. Cryopoor plasma (CPP) was used as a source of canine albumin and intravascular volume. On Day 4, food dye was given through a nasogastric tube due to suspicion of dehiscence of the anastomosis site. Dehiscence was confirmed during abdominal exploratory, and a second resection and anastomosis was performed. Abdominal partial closure with vacuum-assisted closure device was performed. Supportive care was continued with CPP CRI and imipenem CRI. Planned relaparotomy to change the vacuum-assisted closure device was performed 48 hours later, with abdominal closure 96 hours after anastomosis. The patient was discharged on Day 15. Recheck 12 months later was normal.
   New or Unique Information Provided - This case includes novel techniques such food dye via nasogastric tube to identify anastomosis dehiscence, use of CPP as a source of canine albumin, and antimicrobial CRI in a dog with septic peritonitis.
C1 [Ropski, Meaghan K.; Guillaumin, Julien; Monnig, Andrea A.; Townsend, Katy; McLoughlin, Mary A.] Ohio State Univ, Dept Clin Sci, 601 Vernon L Tharp St, Columbus, OH 43210 USA.
C3 University System of Ohio; Ohio State University
RP Guillaumin, J (通讯作者)，Ohio State Univ, Dept Clin Sci, 601 Vernon L Tharp St, Columbus, OH 43210 USA.
EM guillaumin.2@osu.edu
RI Guillaumin, Julien/G-5349-2012
OI Guillaumin, Julien/0000-0001-8622-4387; Monnig,
   Anea/0000-0002-0804-8581; Townsend, Katy/0000-0001-6405-0793
CR Adamantos S, 2009, J SMALL ANIM PRACT, V50, P206, DOI 10.1111/j.1748-5827.2009.00752.x
   Aldrich J, 2009, SMALL ANIMAL CRITICA, P122
   ALLEN DA, 1992, J AM ANIM HOSP ASSOC, V28, P70
   Angus BJ, 2000, BRIT J CLIN PHARMACO, V50, P183
   Barker CW, 2003, AM J VET RES, V64, P694, DOI 10.2460/ajvr.2003.64.694
   Bonczynski JJ, 2003, VET SURG, V32, P161, DOI 10.1053/jvet.2003.50005
   Boussekey N, 2010, CRIT CARE, V14, DOI 10.1186/cc8920
   Caironi P, 2014, NEW ENGL J MED, V370, P1412, DOI 10.1056/NEJMoa1305727
   Chan DL, 2008, VET CLIN N AM-SMALL, V38, P587, DOI 10.1016/j.cvsm.2008.01.006
   Conti-Patara A, 2012, J VET EMERG CRIT CAR, V22, P409, DOI 10.1111/j.1476-4431.2012.00769.x
   Courter JD, 2009, PEDIATR BLOOD CANCER, V53, P379, DOI 10.1002/pbc.22051
   Craft EM, 2012, J VET EMERG CRIT CAR, V22, P631, DOI 10.1111/j.1476-4431.2012.00819.x
   Davidow B, 2013, VET CLIN N AM-SMALL, V43, P735, DOI 10.1016/j.cvsm.2013.03.007
   Dulhunty JM, 2013, CLIN INFECT DIS, V56, P236, DOI 10.1093/cid/cis856
   Feldman B.F., 2004, Practical Transfusion Medicine for the Small Animal Practitioner, P15
   Finfer S, 2011, INTENS CARE MED, V37, P86, DOI 10.1007/s00134-010-2039-6
   Godet G, 2008, EUR J ANAESTH, V25, P986, DOI 10.1017/S026502150800447X
   Grimes J, 2013, J AM ANIM HOSP ASSOC, V49, P246, DOI 10.5326/JAAHA-MS-5870
   Martin LG, 2008, JAVMA-J AM VET MED A, V232, P1004, DOI 10.2460/javma.232.7.1004
   MATHEWS K.A., 2006, FLUID ELECTROLYTE AC, P377
   Metheny NA, 1997, CHEST, V111, P724, DOI 10.1378/chest.111.3.724
   Mouat EE, 2014, J AM ANIM HOSP ASSOC, V50, P254, DOI 10.5326/JAAHA-MS-6111
   Mutter TC, 2013, COCHRANE DB SYST REV, V7, DOI DOI 10.1002/14651858.CD007594.PUB3
   Neto AS, 2014, J CRIT CARE, V29, DOI 10.1016/j.jcrc.2013.09.031
   Plumb D, 2011, PLUMBS VET DRUG HDB, P176
   Powell C, 2013, J VET EMERG CRIT CAR, V23, P598, DOI 10.1111/vec.12085
   Prosst RL, 2005, EUR SURG RES, V37, P246, DOI 10.1159/000087871
   Rafati MR, 2006, INT J ANTIMICROB AG, V28, P122, DOI 10.1016/j.ijantimicag.2006.02.020
   Ralphs SC, 2003, J AM VET MED ASSOC, V223, P73, DOI 10.2460/javma.2003.223.73
   Roberts JA, 2008, CURR OPIN CRIT CARE, V14, P390, DOI 10.1097/MCC.0b013e3283021b3a
   Roberts JA, 2007, J ANTIMICROB CHEMOTH, V59, P285, DOI [10.1093/jac/dk1478, 10.1093/jac/dkl478]
   Roberts JA, 2010, INT J ANTIMICROB AG, V36, P332, DOI 10.1016/j.ijantimicag.2010.06.008
   Roberts JA, 2009, J ANTIMICROB CHEMOTH, V64, P142, DOI 10.1093/jac/dkp139
   Roux F, 2013, J VET EMERG CRIT CAR, V23, pS17
   Sakka SG, 2007, ANTIMICROB AGENTS CH, V51, P3304, DOI 10.1128/AAC.01318-06
   Sakran N, 2013, SURG ENDOSC, V27, P240, DOI 10.1007/s00464-012-2426-x
   Shiu J, 2013, COCHRANE DB SYST REV, V3, P1
   Sime FB, 2012, ANN INTENSIVE CARE, V2, DOI 10.1186/2110-5820-2-35
   Snow SJ, 2010, J VET EMERG CRIT CAR, V20, P441, DOI 10.1111/j.1476-4431.2010.00557.x
   Strauss C, 2010, ANN SURG, V251, P647, DOI 10.1097/SLA.0b013e3181c1aeb8
   Szabo SD, 2011, VET SURG, V40, P444, DOI 10.1111/j.1532-950X.2011.00799.x
   Teo J, 2014, INT J ANTIMICROB AG, V43, P403, DOI 10.1016/j.ijantimicag.2014.01.027
   Trow AV, 2008, JAVMA-J AM VET MED A, V233, P607, DOI 10.2460/javma.233.4.607
   Vincent JL, 2011, MINERVA ANESTESIOL, V77, P1190
   Winkler KP, 2000, VET EMERG CRIT CARE, V10, P259
   [No title captured]
NR 46
TC 11
Z9 13
U1 0
U2 11
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1479-3261
EI 1476-4431
J9 J VET EMERG CRIT CAR
JI J. Vet. Emerg. Crit. Care
PD MAY-JUN
PY 2017
VL 27
IS 3
BP 348
EP 356
DI 10.1111/vec.12583
PG 9
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA FA1KE
UT WOS:000405197400010
PM 28135411
DA 2026-07-24
ER

PT J
AU Bussell, HR
   Aufdenblatten, CA
   Gruenenfelder, C
   Altermatt, S
   Tharakan, SJ
AF Bussell, Hannah Rachel
   Aufdenblatten, Christoph Alexander
   Gruenenfelder, Corina
   Altermatt, Stefan
   Tharakan, Sasha Job
TI Comparison of lower extremity fasciotomy wound closure techniques in
   children: vacuum-assisted closure device versus temporary synthetic skin
   replacement
SO EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
LA English
DT Article
DE Compartment syndrome; Lower extremity; Child; Fasciotomy; V; A; C;
   device
ID ACUTE COMPARTMENT SYNDROME; LOWER LEG; FRACTURES; MANAGEMENT; PRESSURES;
   DIAGNOSIS
AB Purpose No clear consensus on the optimal treatment of fasciotomy wounds due to acute compartment syndrome of the lower leg in children exists. We therefore compared two commonly used methods to close fasciotomy wounds, Epigard, a temporary synthetic skin replacement (SSR) and the vacuum-assisted closure (V.A.C.) device, in respect of treatment duration and complication rates. Methods We studied the cases of 27 patients who were treated at our institution for acute compartment syndrome of the lower leg with a fasciotomy over a 10-year period. The fasciotomy wound was either treated with SSR or V.A.C. device. We recorded the number of procedures to definitive wound closure, days to wound closure, hospitalization days and sequelae rate. Results In the V.A.C. device group (18 patients) the mean number of procedures until definitive wound closure was 3.1, mean days until wound closure was 9.4 and mean days of hospitalization was 16.2. One patient suffered from a wound infection and one patient required a full thickness skin graft. In the SSR group (9 patients), the mean number of procedures was 1.8, mean days until definitive wound closure was 4.9 and mean days of hospitalization was 9.9. No sequelae were recorded. There was a statistically significant smaller number of procedures (p value 0.018), fewer days to definitive wound closure (p value 0.002) and fewer hospitalization days (p value 0.005) in the SSR group. Conclusions Both SSR and V.A.C. device are safe and reliable for closure of fasciotomy wounds in children, whereas SSR seems to lead to shorter time until definitive wound closure.
C1 [Bussell, Hannah Rachel; Aufdenblatten, Christoph Alexander; Altermatt, Stefan; Tharakan, Sasha Job] Univ Childrens Hosp Zurich, Dept Pediat Surg, Steinwiessstr 75, CH-8032 Zurich, Switzerland.
C3 University Children's Hospital Zurich
RP Bussell, HR (通讯作者)，Univ Childrens Hosp Zurich, Dept Pediat Surg, Steinwiessstr 75, CH-8032 Zurich, Switzerland.
EM hannah.bussell@kispi.uzh.ch
OI Neeser Bussell, Hannah Rachel/0000-0002-7182-3181
CR Bae DS, 2001, J PEDIATR ORTHOPED, V21, P680, DOI 10.1097/00004694-200109000-00025
   BMJ Publishing Group Ltd, 1943, J. Neurol. Neurosurg. Psychiatry, V6, P81, DOI [10.1136/jnnp.6.1-2.81, DOI 10.1136/JNNP.6.1-2.81]
   Dover M, 2012, J ORTHOP SURG-HONG K, V20, P312, DOI 10.1177/230949901202000309
   Erdös J, 2011, INT ORTHOP, V35, P569, DOI 10.1007/s00264-010-1016-6
   Ferlic PW, 2012, INJURY, V43, P1743, DOI 10.1016/j.injury.2012.06.025
   Fleischmann W, 1996, UNFALLCHIRURG, V99, P283
   Flynn JM, 2011, J BONE JOINT SURG AM, V93A, P937, DOI 10.2106/JBJS.J.00285
   Hug K, 2015, EPIGARD SYNTHETIC SK
   Kakagia D, 2014, INJURY, V45, P890, DOI 10.1016/j.injury.2012.02.002
   KCI, 2014, CLIN GUID REF SOURC
   Moran S G, 2003, J Wound Care, V12, P212
   Murakami M, 2014, ANZ J SURG, V84, P795, DOI 10.1111/ans.12662
   Potter BK, 2012, TECH ORTHOP, V27, P62
   Shore BJ, 2013, J ORTHOP TRAUMA, V27, P616, DOI 10.1097/BOT.0b013e31828f949c
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Staudt JM, 2008, J BONE JOINT SURG BR, V90B, P215, DOI 10.1302/0301-620X.90B2.19678
   Tharakan SJ, 2016, J PEDIATR ORTHOPED, V36, P410, DOI 10.1097/BPO.0000000000000471
   von Volkmann R, 2007, CLIN ORTHOP RELAT R, P20, DOI 10.1097/01.BLO.0b013e318032561f
   Wall CJ, 2010, ANZ J SURG, V80, P151, DOI 10.1111/j.1445-2197.2010.05213.x
NR 19
TC 3
Z9 5
U1 0
U2 3
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 1863-9933
EI 1863-9941
J9 EUR J TRAUMA EMERG S
JI Eur. J. Trauma Emerg. Surg.
PD OCT
PY 2019
VL 45
IS 5
BP 809
EP 814
DI 10.1007/s00068-018-0985-9
PG 6
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA JD5FT
UT WOS:000490009600006
PM 30014272
DA 2026-07-24
ER

PT J
AU Ye, HY
   Xu, XX
   Sun, Y
   Zhao, XH
AF Ye, Hongyu
   Xu, Xinxin
   Sun, Yi
   Zhao, Xiaohang
TI Efficacy of combining a medial superior malleolar perforator flap from
   the posterior tibial artery with a vacuum-assisted closure dressing for
   skin and soft tissue defects of the Achilles tendon area
SO AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
LA English
DT Article
DE Posterior tibial artery; Achilles tendon; perforating branch; skin flap
ID LOWER-EXTREMITY; PROPELLER FLAP; RECONSTRUCTION; REPAIR; FOOT
AB Objective: This randomized clinical trial aimed to investigate the clinical efficacy of combining a medial superior malleolar perforator flap from the posterior tibial artery (PTAPF) with a vacuum -assisted closure (VAC) dressing for skin and soft tissue defects in the Achilles tendon area. Methods: Twenty-eight patients were randomly divided into two equally sized groups: the control group received treatment with a medial superior malleolar perforator flap, while the experimental group was treated with a perforator flap from the posterior tibial artery in combination with a VAC dressing. Perioperative data, including average operative time, intraoperative blood loss, intraoperative complications, time to ambulation, and hospital stay after surgery, were recorded. Clinical outcomes were assessed based on the time to first weight -bearing walking, time to full weight -bearing activity, Visual Analog Scale (VAS) score, American Orthopaedic Foot and Ankle Society hindfoot and ankle score, and the range of motion for ankle plantar flexion. Results: The patients were monitored for 3-12 months (average, 8.5), and it was observed that the flaps remained stable without enlargement, and their texture and color were similar to the surrounding tissue. Significantly enhanced postoperative indices were noted in the experimental group compared to the control group (P<0.05). Conclusion: The medial superior malleolar perforator flap from the posterior tibial artery, especially when combined with a VAC dressing, proves to be an effective method for repairing medium-sized skin defects in the Achilles tendon area. This approach offers several benefits, including a reliable blood supply, simplicity of the procedure, decreased damage to the donor site, improved aesthetic outcomes, and fewer postoperative complications.
C1 [Ye, Hongyu; Sun, Yi; Zhao, Xiaohang] Yongkang Orthoped Hosp, Dept Microsurg, 9 Wenhuagong Rd,Xicheng St, Yongkang 321300, Zhejiang, Peoples R China.
   [Xu, Xinxin] Dongyang Tradit Chinese Med Hosp, Dept Internal Med, Dongyang 321300, Zhejiang, Peoples R China.
RP Zhao, XH (通讯作者)，Yongkang Orthoped Hosp, Dept Microsurg, 9 Wenhuagong Rd,Xicheng St, Yongkang 321300, Zhejiang, Peoples R China.
EM Xiaohangzhao@yeah.net
RI Sun, Yi/A-5544-2016
FU Natural Scien- ce Foundation of Anhui Province [2108085- MH289]
FX <BOLD>Acknowledgements</BOLD> This work was supported by the Natural
   Scien- ce Foundation of Anhui Province (2108085- MH289) .
CR Abhyankar SV, 2009, ANN PLAS SURG, V63, P425, DOI 10.1097/SAP.0b013e31819516cc
   Al-Himdani S, 2020, INJURY, V51, P1077, DOI 10.1016/j.injury.2020.02.060
   Baumeister SP, 2003, PLAST RECONSTR SURG, V112, P129, DOI 10.1097/01.PRS.0000066167.68966.66
   Chang SM, 2014, ANN PLAS SURG, V72, P340, DOI 10.1097/SAP.0b013e31826108f1
   Deek NFA, 2020, PLAST RECONSTR SURG, V146, p630E, DOI 10.1097/PRS.0000000000007282
   Ding DY, 2016, ARTHROSC TEC, V5, pE525, DOI 10.1016/j.eats.2016.02.016
   Fang Jie, 2021, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V35, P508, DOI 10.7507/1002-1892.202011032
   Fritz C, 2021, MICROSURG, V41, P660, DOI 10.1002/micr.30790
   Grishkevich VM, 2014, J BURN CARE RES, V35, pE143, DOI 10.1097/BCR.0b013e3182a2a74f
   Huang HH, 2023, J PLAST RECONSTR AES, V77, P31, DOI 10.1016/j.bjps.2022.11.009
   Kilinc H, 2006, ANN PLAS SURG, V57, P396, DOI 10.1097/01.sap.0000237573.63778.bb
   Liu FC, 2021, PLAST RECONSTR SURG, V148, p14E, DOI 10.1097/PRS.0000000000008099
   Liu J, 2015, J PLAST SURG HAND SU, V49, P102, DOI 10.3109/2000656X.2014.922979
   Massarelli O, 2014, PLAST RECONSTR SURG, V133, P130, DOI 10.1097/01.prs.0000435845.33670.64
   O'Connor EF, 2020, FOOT ANKLE SURG, V26, P233, DOI 10.1016/j.fas.2019.02.003
   Pan Xiaohua, 2017, Open Orthop J, V11, P704, DOI [10.2174/1874325001711010704, 10.2174/1874325001711010704]
   Parodi Pier Camillo, 2006, Ann Ital Chir, V77, P361
   Rad AN, 2008, MICROSURG, V28, P663, DOI 10.1002/micr.20557
   Ran Xiaoye, 2022, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V36, P451, DOI 10.7507/1002-1892.202111047
   Repta R, 2005, ANN PLAS SURG, V55, P367, DOI 10.1097/01.sap.0000181342.25065.60
   Shen LF, 2017, J INT MED RES, V45, P1074, DOI 10.1177/0300060516687229
   Sun C, 2013, PLAST RECONSTR SURG, V131, P329, DOI 10.1097/PRS.0b013e318277884c
   Vaienti L, 2013, J ORTHOP TRAUMATOL, V14, P213, DOI 10.1007/s10195-013-0236-0
   Venkataramakrishnan V, 1998, BRIT J PLAST SURG, V51, P431, DOI 10.1054/bjps.1997.0229
   Wang Wei, 2020, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V34, P87, DOI 10.7507/1002-1892.201904095
   Wang Yaojun, 2018, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V32, P1187, DOI 10.7507/1002-1892.201803046
   Wang Zheng, 2019, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V33, P1196, DOI 10.7507/1002-1892.201902047
   Wilcox DK, 2000, FOOT ANKLE INT, V21, P1004, DOI 10.1177/107110070002101204
   Yildirim S, 2007, ANN PLAS SURG, V58, P501, DOI 10.1097/01.sap.0000247953.36082.f4
   Yuan KZ, 2021, ANN PLAS SURG, V86, P668, DOI 10.1097/SAP.0000000000002811
   Zhang C, 2017, Zhonghua Shao Shang Za Zhi, V33, P602, DOI 10.3760/cma.j.issn.1009-2587.2017.10.003
   Zhou Xiao, 2014, Zhonghua Zheng Xing Wai Ke Za Zhi, V30, P255
NR 32
TC 2
Z9 3
U1 0
U2 6
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1943-8141
J9 AM J TRANSL RES
JI Am. J. Transl. Res.
PY 2024
VL 16
IS 4
BP 1209
EP 1218
PG 10
WC Oncology; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Research & Experimental Medicine
GA PO3B0
UT WOS:001214968800018
PM 38715817
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Hou, ZY
   Irgit, K
   Strohecker, KA
   Matzko, ME
   Wingert, NC
   DeSantis, JG
   Smith, WR
AF Hou, Zhiyong
   Irgit, Kaan
   Strohecker, Kent A.
   Matzko, Michelle E.
   Wingert, Nathaniel C.
   DeSantis, Joseph G.
   Smith, Wade R.
TI Delayed Flap Reconstruction With Vacuum-Assisted Closure Management of
   the Open IIIB Tibial Fracture
SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
LA English
DT Article
DE VAC; Open fractures; Wounds; IIIB; Delayed closure; Complication
ID PRESSURE WOUND THERAPY; SOFT-TISSUE INJURIES; LOWER-EXTREMITY; COVERAGE;
   DEFECTS
AB Objective: Vacuum-assisted closure (VAC) therapy has been shown to be effective at reducing bacterial counts in wounds until definitive bony coverage. However, there is continued debate over timing and type of definitive wound coverage even with VAC therapy application.
   Methods: From 2004 to 2009, 32 patients with Gustilo type IIIB open tibia fractures were initially treated with VAC therapy were included. The number of debridements, length of treatment with VAC dressing, definitive wound coverage management, and length of hospital stay, flap-related complications, and time to radiographic fracture healing were recorded.
   Results: The mean Injury Severity Score was 17.3 +/- 2.0. All wounds closed after being treated with the primary VAC closure. The mean interval between the initial injury and definitive intervention was 10.9 days +/- 0.3 days. Twenty of 27 patients (74%) underwent rotational muscle flaps; four received free muscle flaps and three only with split-thickness skin grafts for definitive wound coverage. Nine of 32 patients (28%) underwent below knee amputation, five without flap coverage after several VAC sessions and four after definitive flap coverage. The average time to union was 10.0 months +/- 2.0 months. Eight patients developed nonunion and 11 patients developed infections. The average follow-up time is 2.4 years +/- 0.2 years. Patients were divided into two groups for analysis according to the interval time. The rate of infection was significantly increased in patients who had an interval of more than 7 days from the time of injury to flap coverage.
   Conclusions: The VAC therapy may help to reduce the flap size and need for a flap transfer for type IIIB open tibial fractures. However, prolonged periods of VAC usage, greater than 7 days, should be avoided to reduce higher infection and amputation risks.
C1 [Hou, Zhiyong] Hebei Med Univ, Hosp 3, Dept Orthopaed Surg, Shijiazhuang 050051, Hebei, Peoples R China.
   [Smith, Wade R.] Mt Orthopaed Trauma Surg Swedish, Englewood, CO USA.
   [Irgit, Kaan; Strohecker, Kent A.; Matzko, Michelle E.; Wingert, Nathaniel C.; DeSantis, Joseph G.] Geisinger Med Ctr, Dept Orthopaed Surg, Danville, PA 17822 USA.
C3 Hebei Medical University; Geisinger Medical Center
RP Hou, ZY (通讯作者)，Hebei Med Univ, Hosp 3, Dept Orthopaed Surg, Shijiazhuang 050051, Hebei, Peoples R China.
EM hzy707@yahoo.com.cn
OI MATZKO, MICHELLE/0000-0003-3544-0826; Hou, Zhiyong/0000-0001-5838-4025
CR Adams WP, 2004, ANN PLAS SURG, V53, P6, DOI 10.1097/01.sap.0000106430.56501.b5
   Bhattacharyya T, 2008, PLAST RECONSTR SURG, V121, P1263, DOI 10.1097/01.prs.0000305536.09242.a6
   Burns TC, 2010, J ORTHOP TRAUMA, V24, P697, DOI 10.1097/BOT.0b013e3181d048b8
   Busse JW, 2007, J ORTHOP TRAUMA, V21, P70, DOI 10.1097/BOT.0b013e31802cbc43
   BYRD HS, 1985, PLAST RECONSTR SURG, V76, P719, DOI 10.1097/00006534-198511000-00011
   COLE JD, 1995, CLIN ORTHOP RELAT R, P84
   Dedmond BT, 2007, J ORTHOP TRAUMA, V21, P11, DOI 10.1097/BOT.0b013e31802cbc54
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Gopal S, 2000, J BONE JOINT SURG BR, V82B, P959, DOI 10.1302/0301-620X.82B7.10482
   GUSTILO RB, 1987, ORTHOPEDICS, V10, P1781
   GUSTILO RB, 1990, J BONE JOINT SURG AM, V72A, P299, DOI 10.2106/00004623-199072020-00023
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   KHOURI RK, 1989, J TRAUMA, V29, P1086, DOI 10.1097/00005373-198908000-00005
   MARKS MW, 1988, ANN PLAS SURG, V20, P261, DOI 10.1097/00000637-198803000-00014
   Mooney JF, 2000, CLIN ORTHOP RELAT R, P26
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Nieminen H, 1999, J TRAUMA, V46, P1031, DOI 10.1097/00005373-199906000-00008
   Pollak AN, 2000, J BONE JOINT SURG AM, V82A, P1681, DOI 10.2106/00004623-200012000-00001
   Rinker B, 2008, PLAST RECONSTR SURG, V121, P1664, DOI 10.1097/PRS.0b013e31816a8d9d
   RUSSELL GG, 1990, J BONE JOINT SURG BR, V72, P125, DOI 10.1302/0301-620X.72B1.2298770
   SANDERS R, 1994, AAOS INSTR COURS LEC, V43, P559
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Webb LX, 2007, J BONE JOINT SURG AM, V89A, P923, DOI 10.2106/JBJS.F.00776
   Weitz-Marshall Amanda D, 2002, J Am Acad Orthop Surg, V10, P379
NR 25
TC 83
Z9 101
U1 1
U2 12
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0022-5282
J9 J TRAUMA
JI J. Trauma-Injury Infect. Crit. Care
PD DEC
PY 2011
VL 71
IS 6
BP 1705
EP 1708
DI 10.1097/TA.0b013e31822e2823
PG 4
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Surgery
GA 869RT
UT WOS:000298616400047
PM 22182878
DA 2026-07-24
ER

PT J
AU Sziklavari, Z
   Grosser, C
   Neu, R
   Schemm, R
   Kortner, A
   Szöke, T
   Hofmann, HS
AF Sziklavari, Zsolt
   Grosser, Christian
   Neu, Reiner
   Schemm, Rudolf
   Kortner, Ariane
   Szoeke, Tamas
   Hofmann, Hans-Stefan
TI Complex pleural empyema can be safely treated with vacuum-assisted
   closure
SO JOURNAL OF CARDIOTHORACIC SURGERY
LA English
DT Article
ID OPEN WINDOW THORACOSTOMY; THORACIC EMPYEMA; INTRATHORACIC APPLICATION;
   MANAGEMENT; THERAPY; SURGERY
AB Objective: For patients with postoperative pleural empyema, open window thoracostomy (OWT) is often necessary to prevent sepsis. Vacuum-assisted closure (VAC) is a well-known therapeutic option in wound treatment. The efficacy and safety of intrathoracal VAC therapy, especially in patients with pleural empyema with bronchial stump insufficiency or remain lung, has not yet been investigated.
   Methods: Between October 2009 and July 2010, eight consecutive patients (mean age of 66.1 years) with multimorbidity received an OWT with VAC for the treatment of postoperative or recurrent pleural empyema. Two of them had a bronchial stump insufficiency (BPF).
   Results: VAC therapy ensured local control of the empyema and control of sepsis. The continuous suction up to 125 mm Hg cleaned the wound and thoracic cavity and supported the rapid healing. Additionally, installation of a stable vacuum was possible in the two patients with BPF. The smaller bronchus stump fistula closed spontaneously due to the VAC therapy, but the larger remained open.
   The direct contact of the VAC sponge did not create any air leak or bleeding from the lung or the mediastinal structures. The VAC therapy allowed a better re-expansion of remaining lung.
   One patient died in the late postoperative period (day 47 p.o.) of multiorgan failure. In three cases, VAC therapy was continued in an outpatient service, and in four patients, the OWT was treated with conventional wound care. After a mean time of three months, the chest wall was closed in five of seven cases. However, two patients rejected the closure of the OWT. After a follow-up at 7.7 months, neither recurrent pleural empyema nor BPF was observed.
   Conclusion: VAC therapy was effective and safe in the treatment of complicated pleural empyema. The presence of smaller bronchial stump fistula and of residual lung tissue are not a contraindication for VAC therapy.
C1 [Sziklavari, Zsolt; Grosser, Christian; Schemm, Rudolf; Szoeke, Tamas; Hofmann, Hans-Stefan] Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, D-93049 Regensburg, Germany.
   [Neu, Reiner; Kortner, Ariane; Hofmann, Hans-Stefan] Univ Regensburg, Dept Thorac Surg, D-93053 Regensburg, Germany.
C3 University of Regensburg
RP Sziklavari, Z (通讯作者)，Hosp Barmherzige Bruder Regensburg, Dept Thorac Surg, Prufeningerstr 86, D-93049 Regensburg, Germany.
EM zsolt.sziklavari@barmherzige-regensburg.de
RI Sziklavari, Zsolt/AGI-2440-2022
CR Deslauriers Jean, 2002, Chest Surg Clin N Am, V12, P605, DOI 10.1016/S1052-3359(02)00017-0
   GIORGIO M, 2010, ANN THORAC SURG, V90, P266
   Groetzner J, 2009, THORAC CARDIOV SURG, V57, P417, DOI 10.1055/s-0029-1185907
   LEMMER JH, 1985, J THORAC CARDIOV SUR, V90, P849
   LIGHT RW, 1995, CHEST, V108, P299, DOI 10.1378/chest.108.2.299
   Maruyama R, 2001, RESPIRATION, V68, P606, DOI 10.1159/000050580
   Massera F, 2006, ANN THORAC SURG, V82, P288, DOI 10.1016/j.athoracsur.2005.11.046
   Matzi V, 2006, ZBL CHIR, V131, pS139, DOI 10.1055/s-2006-921474
   Molnar TF, 2007, EUR J CARDIO-THORAC, V32, P422, DOI 10.1016/j.ejcts.2007.05.028
   Palmen M, 2009, ANN THORAC SURG, V88, P1131, DOI 10.1016/j.athoracsur.2009.06.030
   Renner C, 2010, ANN THORAC SURG, V89, P603, DOI 10.1016/j.athoracsur.2009.06.037
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Varker KA, 2006, ANN THORAC SURG, V81, P723, DOI 10.1016/j.athoracsur.2004.10.040
NR 13
TC 22
Z9 40
U1 0
U2 2
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1749-8090
J9 J CARDIOTHORAC SURG
JI J. Cardiothorac. Surg.
PD OCT 6
PY 2011
VL 6
AR 130
DI 10.1186/1749-8090-6-130
PG 6
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 841IZ
UT WOS:000296507300001
PM 21978620
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kneser, U
   Leffler, M
   Bach, AD
   Kopp, J
   Horch, RE
AF Kneser, U
   Leffler, M
   Bach, AD
   Kopp, J
   Horch, RE
TI Vacuum Assisted Closure (VAC®) therapy is an essential tool for
   treatment of complex defect injuries of the upper extremity
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nurnberg, GERMANY
ID FASCIOTOMY; TRAUMA
AB Introduction: Complex injuries of the upper extremity remain a therapeutic challenge. The prognosis of the damaged extremity is often limited by soft tissue defects. Vacuum Assisted Closure (V.A.C.(R)) therapy facilitates temporary coverage of soft tissue defects prior to surgical reconstruction. Methods: In a retrospective study all patients with complex defect injuries of the upper extremity that were treated by V.A.C.(R) prior to reconstruction between August 2003 and September 2005 were analyzed. Results: 7 patients (6 male, 1 female, 14-70 years) were included in the study. The patients suffered from subtotal upper arm (n = 1) and forearm (n = 1) amputation, complex multilevel amputation injury of the forearm (n = 1), slash wound of the forearm with skin defect and discontinuity of all volar structures (n = 1), complex open forearm fractures with skin and soft tissue defects (n = 2), and almost complete necrosis of the flexor compartment following distal radius and proximal ulnar fracture and compartment syndrome (n = 1). Stabile defect coverage was achieved in all patients following V.A.C.(R) therapy by myocutaneous free flaps (n = 2), split thickness skin grafts (STSG) (n = 2), sequential secondary suture (n = 1), and STSG + secondary suture (n = 2). Wound conditions improved significantly under V.A.C.(R) therapy. 5 patients reported pain relief following induction of V.A.C.(R) therapy. Due to reduction of tissue oedema secondary suture was facilitated in 3 patients. Discussion: V.A.C.(R) therapy represents an essential tool for treatment of complex injuries of the upper extremity with extended soft tissue defects. Decreased frequency of dressing changes as well as reduced tissue oedema considerably improved patient's comfort. Posttraumatic compartment syndrome or skin necrosis, which are often associated with macro amputations of the upper extremity, are efficiently treated with V.A.C.(R), and secondary sutures may be performed despite initial skin defects.
C1 Univ Klinikum Erlangen, Chirurg Univ Klin, Abt Plast & Handchirurg, D-91054 Erlangen, Germany.
C3 University of Erlangen Nuremberg
RP Kneser, U (通讯作者)，Univ Klinikum Erlangen, Chirurg Univ Klin, Abt Plast & Handchirurg, Krankenhausstr 12, D-91054 Erlangen, Germany.
EM ulrich.kneser@chir.imed.uni-erlangen.de
RI Horch, Raymund E/H-8128-2019
OI Horch, Raymund E/0000-0002-6561-2353
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   AXELROD TS, 1991, J HAND SURG-AM, V16A, P574, DOI 10.1016/0363-5023(91)90176-C
   Blum J, 2005, UNFALLCHIRURG, V108, P843, DOI 10.1007/s00113-005-1003-3
   Dente CJ, 2004, AM SURGEON, V70, P1088
   Derderian CA, 2003, J RECONSTR MICROSURG, V19, P455
   FELICIANO DV, 1988, AM J SURG, V156, P533, DOI 10.1016/S0002-9610(88)80547-6
   Fields CE, 2002, SURG CLIN N AM, V82, P105, DOI 10.1016/S0039-6109(03)00143-9
   Fleischmann W, 1996, UNFALLCHIRURG, V99, P283
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   Horch RE, 2003, MMW-FORTSCH MEDIZIN, V13, P42
   Lin SH, 2004, J RECONSTR MICROSURG, V20, P227
   Schipper J, 2003, LARYNGO RHINO OTOL, V82, P421
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   VITALE GC, 1988, SURG GYNECOL OBSTET, V166, P397
   von Gossler C M, 2000, J Cutan Med Surg, V4, P219
   von Schroeder HP, 1998, HAND CLIN, V14, P451
   WEBB LX, 2002, J AM ACAD ORTHOP SUR, V5, P303
NR 17
TC 20
Z9 20
U1 0
U2 2
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S7
EP S12
DI 10.1055/s-2006-921470
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 034DB
UT WOS:000236904100003
PM 16575636
DA 2026-07-24
ER

PT J
AU Waltzman, JT
   Bell, DE
AF Waltzman, Joshua T.
   Bell, Derek E.
TI Vacuum-Assisted Closure Device as a Split-Thickness Skin Graft Bolster
   in the Burn Population
SO JOURNAL OF BURN CARE & RESEARCH
LA English
DT Article
ID ALCOHOL; INJURY; FIRES; RISK
AB The vacuum-assisted closure device (VAC) is associated with improved wound healing outcomes. Its use as a bolster device to secure a split-thickness skin graft has been previously demonstrated; however, there is little published evidence demonstrating its benefits specifically in the burn population. With use of the VAC becoming more commonplace, its effect on skin graft take and overall time to healing in burn patients deserves further investigation. Retrospective review of burn registry database at a high-volume level I trauma center and regional burn center during a 16-month period was performed. Patients who had a third-degree burn injury requiring a split-thickness skin graft and who received a VAC bolster were included. Data points included age, sex, burn mechanism, burn location, grafted area in square centimeters, need for repeat grafting, percent graft take, and time to complete reepithelialization. Sixty-seven patients were included in the study with a total of 88 skin graft sites secured with a VAC. Age ranged from <1 year to 84 years (average 41 years). The average grafted area was 367 +/- 545 cm(2). The three most common were the leg, thigh, and arm (28, 15, and 12%, respectively). Average percent graft take was 99.5 +/- 1.5%. Notably, no patients returned to the operating room for repeat grafting. The average time to complete reepithelialization was 16 +/- 7 days. The VAC is a highly reliable and reproducible method to bolster a split-thickness skin graft in the burn population. The observed rate of zero returns to the operating room for repeat grafting was especially encouraging. Its ability to conform to contours of the body and cover large surface areas makes it especially useful in securing a graft. This method of bolstering results in decreased repeat grafting and minimal graft loss, thus decreasing morbidity compared with conventional bolster dressings.
C1 [Waltzman, Joshua T.; Bell, Derek E.] Univ Rochester, Med Ctr, Div Plast Surg, Rochester, NY 14642 USA.
C3 University of Rochester
RP Bell, DE (通讯作者)，Univ Rochester, Med Ctr, Div Plast Surg, Strong Mem Hosp, 601 Elmwood Ave,Box 661, Rochester, NY 14642 USA.
CR ALLER RD, 1982, JAMA-J AM MED ASSOC, V248, P1451, DOI 10.1001/jama.1982.03330120021019
   BARUCHIN AM, 1986, BURNS, V12, P288, DOI 10.1016/0305-4179(86)90133-6
   Brown TPL, 2003, ANZ J SURG, V73, p550B
   CHAKRABARTY KH, 1994, BURNS, V20, P367, DOI 10.1016/0305-4179(94)90071-X
   Fong EP, 2000, BURNS, V26, P673, DOI 10.1016/S0305-4179(00)00020-6
   Foster SE, 2003, JAMA-J AM MED ASSOC, V289, P989, DOI 10.1001/jama.289.8.989
   Helmenstein AM, GLOWING FLAMING COCK
   Holmes WJM, 2010, BURNS, V36, P938, DOI 10.1016/j.burns.2009.12.008
   HOWLAND J, 1987, PUBLIC HEALTH REP, V102, P475
   Jang YC, 2006, J BURN CARE RES, V27, P93, DOI 10.1097/01.bcr.0000192264.90796.23
   Jones L, 2011, HEALTH PLACE, V17, P508, DOI 10.1016/j.healthplace.2010.12.006
   JURKOVICH GJ, 1993, JAMA-J AM MED ASSOC, V270, P51, DOI 10.1001/jama.270.1.51
   Spigelman AD, 2005, ANZ J SURG, V75, P556, DOI 10.1111/j.1445-2197.2005.03429.x
   Still J, 1997, AM SURGEON, V63, P252
   Syson N, 2012, SUN, P6
   Tooher R, 2004, ANZ J SURG, V74, P382, DOI 10.1111/j.1445-1433.2004.02997.x
   Warda L, 1999, Inj Prev, V5, P145
NR 17
TC 31
Z9 35
U1 0
U2 3
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1559-047X
EI 1559-0488
J9 J BURN CARE RES
JI J. Burn Care Res.
PD SEP-OCT
PY 2014
VL 35
IS 5
BP E338
EP E345
DI 10.1097/BCR.0000000000000009
PG 8
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA AP5CZ
UT WOS:000342098600008
PM 24577227
DA 2026-07-24
ER

PT J
AU Verhaalen, A
   Watkins, B
   Brasel, K
AF Verhaalen, Amy
   Watkins, Bruce
   Brasel, Karen
TI Techniques and Cost Effectiveness of Enteroatmospheric Fistula Isolation
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID MANAGEMENT
AB Background. The following describes successful isolation of enteroatmospheric fistulae within a negative pressure wound therapy system (V.A.C.(R), KCI, San Antonio, TX). Methods. An impermeable. tubular structure was placed around the fistula with a dressing applied to the surrounding wound base, dressed with an impermeable drape and negative pressure, and then an ostomy appliance was placed over the isolated fistula stoma. Cost analysis compared traditional dressings to the NPWT isolation method. Results. All patients underwent fistula isolation with complete diversion of enteric contents. Typical dressing changes occurred 3 times per week. Four patients were discharged from the hospital prior to surgical repair. Conclusion. Successful isolation of enteroatmospheric fistulae using a NPWT system has the potential to lower healthcare system costs by allowing for earlier hospital discharge.
C1 [Verhaalen, Amy; Watkins, Bruce; Brasel, Karen] Med Coll Wisconsin, Dept Gen Trauma & Crit Care Surg, Milwaukee, WI 53226 USA.
C3 Medical College of Wisconsin
RP Verhaalen, A (通讯作者)，9200 W Wisconsin, Milwaukee, WI 53226 USA.
EM averhaal@mcw.edu
CR Edelmann G, 1979, Chirurgie, V105, P503
   Goverman J, 2006, J TRAUMA, V60, P428, DOI 10.1097/01.ta.0000203588.66012.c4
   Kordasiewicz Lynn M, 2004, J Wound Ostomy Continence Nurs, V31, P150
   Lloyd DAJ, 2006, BRIT J SURG, V93, P1045, DOI 10.1002/bjs.5396
   SCAFF DW, 2007, INJURY EXTRA, V38, P43
   TREZISE F, 2006, USING EAKIN MANAGING
   Wild T, 2007, Ther Umsch, V64, P495, DOI 10.1024/0040-5930.64.9.495
NR 7
TC 18
Z9 22
U1 0
U2 5
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD AUG
PY 2010
VL 22
IS 8
BP 212
EP 217
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 643LS
UT WOS:000281298600006
PM 25901513
DA 2026-07-24
ER

PT J
AU Wondberg, D
   Larusson, HJ
   Metzger, U
   Platz, A
   Zingg, U
AF Wondberg, D.
   Larusson, H. J.
   Metzger, U.
   Platz, A.
   Zingg, U.
TI Treatment of the Open Abdomen with the Commercially Available
   Vacuum-Assisted Closure System in Patients with Abdominal Sepsis
SO WORLD JOURNAL OF SURGERY
LA English
DT Article; Proceedings Paper
CT International Surgical Week Conference
CY AUG 26-30, 2007
CL Montreal, CANADA
ID FASCIAL CLOSURE; WOUND CLOSURE; VENTRAL HERNIA; PACK TECHNIQUE;
   EXPERIENCE; DEVICE
AB Abdominal Vacuum-Assisted Closure (V.A.C.) systems for treatment of open abdomens have been predominantly used for trauma patients with a high primary fascial closure rate. Use of the V.A.C. technique in abdominal sepsis is less well established.
   All patients with abdominal sepsis and treatment with the abdominal V.A.C. system between 2004 and 2007 were prospectively assessed. End points were fascial closure, V.A.C.-related morbidity, and quality of life score (SF-36) at follow-up.
   Thirty patients with abdominal sepsis were included in the study. Primary fascial closure was feasible in 10, partial closure in 4, and no closure in 16 patients. Median number of V.A.C. changes was 3 (range, 1-10). Nine patients died. V.A.C.-related morbidity was as follows: two fistulas, three fascial edge necroses, one skin blister, and four prolapses of small bowel between the fascia and foam. Univariate analysis showed no variables influencing primary closure rate or V.A.C.-related morbidity. Mortality was significantly influenced by age (P < 0.001), respiratory failure (P = 0.01), and pneumonia (P = 0.03). At follow-up, V.A.C. patients scored lower in the physical health scores and similar in the mental health scores compared with the normal population.
   Treatment of the open abdomen in patients with abdominal sepsis with the abdominal V.A.C. system is safe with good long-term quality of life. Primary closure rate in these patients is substantially lower than in trauma patients. Stepwise closure of the fascia during V.A.C. changes should be attempted to avoid additional lateral retraction of fascial edges. V.A.C.-related complications may be avoided with careful surgical technique.
C1 [Larusson, H. J.; Zingg, U.] Univ Basel Hosp, Dept Surg, CH-4031 Basel, Switzerland.
   [Wondberg, D.; Metzger, U.; Platz, A.; Zingg, U.] Triemli Hosp Zurich, Dept Surg, CH-8063 Zurich, Switzerland.
C3 University of Basel; Triemli Hospital
RP Zingg, U (通讯作者)，Univ Basel Hosp, Dept Surg, Spitalstr 21, CH-4031 Basel, Switzerland.
EM uzingg@uhbs.ch
OI Zingg, Urs/0000-0001-9751-4064
CR Adkins AL, 2004, AM SURGEON, V70, P137
   [Anonymous], EUR J TRAUMA
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   BULLINGER M, 1995, SOC SCI MED, V41, P1359, DOI 10.1016/0277-9536(95)00115-N
   Calandra T, 2005, CRIT CARE MED, V33, P1538, DOI 10.1097/01.CCM.0000168253.91200.83
   Cipolla J, 2005, AM SURGEON, V71, P202
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   Fernandez L, 1996, J TRAUMA, V40, P258, DOI 10.1097/00005373-199602000-00014
   Ivancevic N, 2008, LANGENBECK ARCH SURG, V393, P397, DOI 10.1007/s00423-007-0239-5
   LINDER MM, 1987, CHIRURG, V58, P84
   Maier S, 2005, CHIRURG, V76, P829, DOI 10.1007/s00104-005-1066-2
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Miller PR, 2002, J TRAUMA, V53, P843, DOI 10.1097/00005373-200211000-00007
   Nagy KK, 1996, AM SURGEON, V62, P331
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   Oetting P, 2006, CHIRURG, V77, P586, DOI 10.1007/s00104-006-1200-9
   Olejnik J, 2007, BRATISL MED J, V108, P320
   Perez D, 2007, J AM COLL SURGEONS, V205, P586, DOI 10.1016/j.jamcollsurg.2007.05.015
   Petersson U, 2007, WORLD J SURG, V31, P2133, DOI 10.1007/s00268-007-9222-0
   Rao M, 2007, COLORECTAL DIS, V9, P266, DOI 10.1111/j.1463-1318.2006.01154.x
   Smith LA, 1997, AM SURGEON, V63, P1102
   Starr-Marshall K, 2007, COLORECTAL DIS, V9, P573, DOI 10.1111/j.1463-1318.2007.01310.x
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   Stonerock CE, 2003, AM SURGEON, V69, P1030
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Tsuei BJ, 2004, AM SURGEON, V70, P652
   Wacha H., 1987, THEOR SURG, V1, P169
NR 28
TC 74
Z9 85
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0364-2313
EI 1432-2323
J9 WORLD J SURG
JI World J.Surg.
PD DEC
PY 2008
VL 32
IS 12
BP 2724
EP 2729
DI 10.1007/s00268-008-9762-y
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 373JS
UT WOS:000260968500032
PM 18836762
DA 2026-07-24
ER

PT J
AU Danielsson, PA
   Fredriksson, C
   Huss, FRM
AF Danielsson, Par A.
   Fredriksson, Camilla
   Huss, Fredrik R. M.
TI A Novel Concept for Treating Large Necrotizing Fasciitis Wounds With
   Bilayer Dermal Matrix, Split-thickness Skin Grafts, and Negative
   Pressure Wound Therapy
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID STREPTOCOCCAL INFECTIONS
AB Treatment of necrotizing fasciitis (NF) includes radical surgical debridement often resulting in large wounds that need to be closed with methods including split-thickness skin grafts (STSG), local flaps, or guided tissue regeneration procedures. In this case report, a 45 year-old Caucasian male was surgically treated for a benign left groin hernia, developed NF, and was transferred to the authors' burn unit. The wound was treated initially with wide debridement and with a brief delay before finally closing the wound. A collagen matrix such as Integra (R) Dermal Regeneration Template (Integra LifeSciences, Plainsboro, NJ) in combination with STSG and negative pressure wound treatment, can provide fast recovery resulting in pliable, functional skin.
C1 [Danielsson, Par A.; Fredriksson, Camilla; Huss, Fredrik R. M.] Linkoping Univ Hosp, Dept Plast Hand & Burn Surg, S-58185 Linkoping, Sweden.
C3 Linkoping University
RP Fredriksson, C (通讯作者)，Linkoping Univ Hosp, Dept Plast Hand & Burn Surg, S-58185 Linkoping, Sweden.
EM Fredrik.huss@lio.se
RI Huss, Fredrik/G-6951-2018
OI Huss, Fredrik/0000-0002-9735-1434
FU Institute of Biomedicine and Surgery; Faculty Of Health Sciences,
   Linkoping Universitet, Linkoping, Sweden
FX We express our sincere gratitude to Mrs. Kristina Briheim and Mrs. Anita
   Lonn, Senior Laboratory Technicians at the Laboratory for Experimental
   Plastic Surgery, Institute of Biomedicine and Surgery, Faculty Of Health
   Sciences, Linkoping Universitet, Linkoping, Sweden.
CR Akhtar S, 2006, BURNS, V32, P251, DOI 10.1016/j.burns.2005.06.009
   Bisno AL, 1996, NEW ENGL J MED, V334, P240, DOI 10.1056/NEJM199601253340407
   BURKE JF, 1981, ANN SURG, V194, P413, DOI 10.1097/00000658-198110000-00005
   Frame JD, 2004, PLAST RECONSTR SURG, V113, P1330, DOI 10.1097/01.PRS.0000111883.93604.85
   Kaul R, 1997, AM J MED, V103, P18, DOI 10.1016/S0002-9343(97)00160-5
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Morykwas M. J., 1997, ANN PLAST SURG, V38, P563
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   STEVENS DL, 1989, NEW ENGL J MED, V321, P1, DOI 10.1056/NEJM198907063210101
   Thompson JT, 2007, CLIN PLAST SURG, V34, P673, DOI 10.1016/j.cps.2007.07.005
NR 11
TC 6
Z9 6
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD AUG
PY 2009
VL 21
IS 8
BP 215
EP 220
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 490BU
UT WOS:000269472900006
PM 25903675
DA 2026-07-24
ER

PT J
AU Katarincic, JA
   Fantry, A
   DePasse, JM
   Feller, R
AF Katarincic, Julia A.
   Fantry, Amanda
   DePasse, J. Mason
   Feller, Ross
TI Local Modalities for Preventing Surgical Site Infections: An
   Evidence-based Review
SO JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
LA English
DT Review
ID PRESSURE WOUND THERAPY; INTRAWOUND VANCOMYCIN POWDER; RESISTANT
   STAPHYLOCOCCUS-AUREUS; POVIDONE-IODINE SOLUTION; TOTAL JOINT
   ARTHROPLASTY; ORTHOPEDIC-SURGERY; CHLORHEXIDINE GLUCONATE; SKIN
   PREPARATION; POSTOPERATIVE INFECTION; ADHESIVE DRAPE
AB Surgical site infections remain a dreaded complication of orthopaedic surgery, affecting both patient economics and quality of life. It is important to note that infections are multifactorial, involving both surgical and patient factors. To decrease the occurrence of infections, surgeons frequently use local modalities, such as methicillin-resistant Staphylococcus aureus screening; preoperative bathing; intraoperative povidone-iodine lavage; and application of vancomycin powder, silver-impregnated dressings, and incisional negative-pressure wound therapy. These modalities can be applied individually or in concert to reduce the incidence of surgical site infections. Despite their frequent use, however, these interventions have limited support in the literature.
C1 [Katarincic, Julia A.; Fantry, Amanda; DePasse, J. Mason; Feller, Ross] Brown Univ, Rhode Isl Hosp, Dept Orthopaed Surg, Warren Alpert Med Sch, Providence, RI 02903 USA.
C3 Lifespan Health Rhode Island; Rhode Island Hospital; Brown University
RP Katarincic, JA (通讯作者)，Brown Univ, Rhode Isl Hosp, Dept Orthopaed Surg, Warren Alpert Med Sch, Providence, RI 02903 USA.
FU Stryker
FX Dr. DePasse or an immediate family member has received nonincome support
   (such as equipment or services), commercially derived honoraria, or
   other non-research-related funding (such as paid travel) from Stryker.
   None of the following authors or any immediate family member has
   received anything of value from or has stock or stock options held in a
   commercial company or institution related directly or indirectly to the
   subject of this article: Dr. Katarincic, Dr. Fantry, and Dr. Feller.
CR Armaghani SJ, 2014, SPINE, V39, P1683, DOI 10.1097/BRS.0000000000000465
   Blom A, 2000, ANN ROY COLL SURG, V82, P405
   Blom AW, 2002, J HOSP INFECT, V52, P52, DOI 10.1053/jhin.2002.1262
   Brown NM, 2012, J ARTHROPLASTY, V27, P27, DOI 10.1016/j.arth.2011.03.034
   Cai J, 2014, J ARTHROPLASTY, V29, P1098, DOI 10.1016/j.arth.2013.11.012
   Chang FY, 2006, EUR SPINE J, V15, P1005, DOI 10.1007/s00586-005-0975-6
   Chen AF, 2013, CLIN ORTHOP RELAT R, V471, P2383, DOI 10.1007/s11999-013-2875-0
   Cheng MT, 2005, SPINE, V30, P1689, DOI 10.1097/01.brs.0000171907.60775.85
   Chlebicki MP, 2013, AM J INFECT CONTROL, V41, P167, DOI 10.1016/j.ajic.2012.02.014
   Chundamala J, 2007, CAN J SURG, V50, P473
   Dizer B, 2009, J CLIN NURS, V18, P3325, DOI 10.1111/j.1365-2702.2009.02885.x
   Edmiston CE Jr, 2015, JAMA SURG, V150, P1027, DOI 10.1001/jamasurg.2015.2210
   Edmiston CE, 2015, ASSOC OPER ROOM NURS, V101, P529, DOI 10.1016/j.aorn.2015.02.008
   Edmiston CE, 2014, J AM COLL SURGEONS, V219, P256, DOI 10.1016/j.jamcollsurg.2014.01.061
   Eiselt D, 2009, ORTHOP NURS, V28, P141, DOI 10.1097/NOR.0b013e3181a469db
   El-Gazzar Y, 2013, J ARTHROPLASTY, V28, P553, DOI 10.1016/j.arth.2012.07.038
   Emohare O, 2014, SPINE J, V14, P2710, DOI 10.1016/j.spinee.2014.03.011
   Falk-Brynhildsen K, 2013, J HOSP INFECT, V84, P151, DOI 10.1016/j.jhin.2013.02.011
   Falk-Brynhildsen K, 2013, BIOL RES NURS, V15, P242, DOI 10.1177/1099800411430381
   Farber NJ, 2013, CLIN ORTHOP RELAT R, V471, P3120, DOI 10.1007/s11999-013-2920-z
   FRENCH MLV, 1976, ANN SURG, V184, P46, DOI 10.1097/00000658-197607000-00008
   Ghobrial GM, 2014, SPINE, V39, P550, DOI 10.1097/BRS.0000000000000241
   Godil SS, 2013, J NEUROSURG-SPINE, V19, P331, DOI 10.3171/2013.6.SPINE121105
   GOLDENHEIM PD, 1993, POSTGRAD MED J, V69, pS62
   Gorwitz RJ, 2008, J INFECT DIS, V197, P1226, DOI 10.1086/533494
   Goyal N, 2013, BONE JOINT J, V95B, P4, DOI [10.1302/0301-620X.95B1.27973, 10.1302/0301-620X.95B1.27937]
   Graling PR, 2013, AORN J, V97, P547, DOI 10.1016/j.aorn.2013.02.009
   Greene LR, 2012, AM J INFECT CONTROL, V40, P384, DOI 10.1016/j.ajic.2011.05.011
   Hacek DM, 2008, CLIN ORTHOP RELAT R, V466, P1349, DOI 10.1007/s11999-008-0210-y
   HALEY CE, 1985, J CLIN MICROBIOL, V21, P991, DOI 10.1128/JCM.21.6.991-992.1985
   Hansen E, 2013, CLIN ORTHOP RELAT R, V471, P3230, DOI 10.1007/s11999-013-2937-3
   Harrop JS, 2012, J AM ACAD ORTHOP SUR, V20, P94, DOI 10.5435/JAAOS-20-02-094
   Heller A, 2015, J SPINAL DISORD TECH, V28, pE584, DOI 10.1097/BSD.0000000000000045
   Hill BW, 2014, ACTA NEUROCHIR, V156, P749, DOI 10.1007/s00701-014-2022-z
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   Johnson AJ, 2013, J KNEE SURG, V26, P213, DOI 10.1055/s-0032-1329232
   Johnson AJ, 2010, J ARTHROPLASTY, V25, P98, DOI 10.1016/j.arth.2010.04.012
   JOHNSTON DH, 1987, BRIT J SURG, V74, P64, DOI 10.1002/bjs.1800740121
   Kalmeijer MD, 2000, INFECT CONT HOSP EP, V21, P319, DOI 10.1086/501763
   Kalmeijer MD, 2002, CLIN INFECT DIS, V35, P353, DOI 10.1086/341025
   Kang DG, 2015, SPINE J, V15, P762, DOI 10.1016/j.spinee.2015.01.030
   Kapadia Bhaveen H, 2015, Surg Technol Int, V26, P351
   Kapadia BH, 2013, J ARTHROPLASTY, V28, P490, DOI 10.1016/j.arth.2012.07.015
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Kim DH, 2010, J BONE JOINT SURG AM, V92A, P1820, DOI 10.2106/JBJS.I.01050
   Kim Hyun Su, 2013, Korean J Spine, V10, P121
   Markatos K, 2015, SURG INFECT, V16, P221, DOI 10.1089/sur.2014.097
   Martin JR, 2014, SPINE, V39, P177, DOI 10.1097/BRS.0000000000000071
   Matar WY, 2010, J BONE JOINT SURG AM, V92A, P36, DOI 10.2106/JBJS.J.01046
   Matsumoto T, 2015, FOOT ANKLE INT, V36, P787, DOI 10.1177/1071100715574934
   O'Neill KR, 2011, SPINE J, V11, P641, DOI 10.1016/j.spinee.2011.04.025
   Ogbemudia AO, 2015, STRATEG TRAUMA LIMB, V10, P95, DOI 10.1007/s11751-015-0226-2
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Pauser J, 2016, INT WOUND J, V13, P663, DOI 10.1111/iwj.12344
   Rao N, 2011, J ARTHROPLASTY, V26, P1501, DOI 10.1016/j.arth.2011.03.014
   Rathbone CR, 2011, J ORTHOP RES, V29, P1070, DOI 10.1002/jor.21343
   Schweizer ML, 2015, JAMA-J AM MED ASSOC, V313, P2162, DOI 10.1001/jama.2015.5387
   Singh K, 2015, J ORTHOP TRAUMATOL, V16, P287, DOI 10.1007/s10195-015-0352-0
   Springer Bryan D, 2015, Am J Orthop (Belle Mead NJ), V44, P415
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Stinner DJ, 2011, J TRAUMA, V71, pS147, DOI 10.1097/TA.0b013e318221944a
   Streubel PN, 2012, J AM ACAD ORTHOP SUR, V20, P564, DOI 10.5435/JAAOS-20-09-564
   Supple L, 2015, INFECT CONT HOSP EP, V36, P1095, DOI 10.1017/ice.2015.124
   Sweet FA, 2011, SPINE, V36, P2084, DOI 10.1097/BRS.0b013e3181ff2cb1
   Theologis AA, 2014, SPINE, V39, P1875, DOI 10.1097/BRS.0000000000000533
   Tubaki VR, 2013, SPINE, V38, P2149, DOI 10.1097/BRS.0000000000000015
   von Eiff C, 2001, NEW ENGL J MED, V344, P11, DOI 10.1056/NEJM200101043440102
   Webster J, 2015, COCHRANE DB SYST REV, V4
   Webster J, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004985.pub5
   Weiser MC, 2015, J BONE JOINT SURG AM, V97A, P1449, DOI 10.2106/JBJS.N.01114
   Whitehouse JD, 2002, INFECT CONT HOSP EP, V23, P183, DOI 10.1086/502033
   Yan HD, 2014, J SHOULDER ELB SURG, V23, P686, DOI 10.1016/j.jse.2014.01.049
NR 72
TC 17
Z9 20
U1 1
U2 9
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1067-151X
EI 1940-5480
J9 J AM ACAD ORTHOP SUR
JI J. Am. Acad. Orthop. Surg.
PD JAN 1
PY 2018
VL 26
IS 1
BP 14
EP 25
DI 10.5435/JAAOS-D-16-00033
PG 12
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA GA1WH
UT WOS:000428107800003
PM 29261553
DA 2026-07-24
ER

PT J
AU Klüter, T
   Fitschen-Oestern, S
   Weuster, M
   Fickenscher, H
   Seekamp, A
   Lippross, S
AF Klueter, T.
   Fitschen-Oestern, S.
   Weuster, M.
   Fickenscher, H.
   Seekamp, A.
   Lippross, S.
TI Toxic shock syndrome after open ankle fracture
SO UNFALLCHIRURG
LA German
DT Article
DE Infection risk; Staphylogenic toxins; Open fracture; Sepsis; Negative
   pressure wound therapy
ID PRESSURE WOUND THERAPY; MANAGEMENT; INFECTION
AB The treatment of open fractures is a challenge for the attending surgeon. Depending on the severity, the risk of infection rises up to 50 %. Local infection up to the point of sepsis can develop in spite of surgical and antimicrobial therapy. The present case demonstrates the case of an 18-year-old man who developed toxic shock syndrome (TSS) after an open ankle fracture. This potentially life-threating syndrome usually presents with the main symptoms of fever, hypotension and exanthema and is caused by toxins, such as toxic shock syndrome toxin 1 (TSST-1) and staphylococcal enterotoxins A-D. In some cases it is associated with cardiopulmonary decompensation and can rapidly progress to multiorgan failure.
C1 [Klueter, T.; Fitschen-Oestern, S.; Weuster, M.; Seekamp, A.; Lippross, S.] Univ Klinikum Schleswig Holstein, Klin Unfallchirurg Traumatol, D-24105 Kiel, Germany.
   [Fickenscher, H.] Univ Klinikum Schleswig Holstein, Inst Infektionsmed, D-24105 Kiel, Germany.
C3 University of Kiel; Schleswig Holstein University Hospital; University
   of Kiel; Schleswig Holstein University Hospital
RP Klüter, T (通讯作者)，Univ Klinikum Schleswig Holstein, Klin Unfallchirurg Traumatol, Campus Kiel,Arnold Heller Str 3, D-24105 Kiel, Germany.
EM Tim.Klueter@uksh.de
RI Fickenscher, Helmut/J-9655-2019
CR CHESNEY PJ, 1981, JAMA-J AM MED ASSOC, V246, P741, DOI 10.1001/jama.246.7.741
   Court-Brown CM, 1998, INJURY, V29, P529, DOI 10.1016/S0020-1383(98)00125-9
   DICKGIESS N, 1987, INFECTION, V15, P351, DOI 10.1007/BF01647737
   Grote S, 2012, ORTHOPADE, V41, P32, DOI 10.1007/s00132-011-1839-x
   HACKETT SP, 1993, J INFECT DIS, V168, P232, DOI 10.1093/infdis/168.1.232
   Heeg K, 1996, CURR TOP MICROBIOL, V216, P83
   Hoff WS, 2011, J TRAUMA, V70, P751, DOI 10.1097/TA.0b013e31820930e5
   Lalliss SJ, 2010, J ORTHOP TRAUMA, V24, P598, DOI 10.1097/BOT.0b013e3181ec45ba
   Lang C, 2003, ANAESTHESIST, V52, P805, DOI 10.1007/s00101-003-0552-5
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Patzakis MJ, 1999, CLIN ORTHOP RELAT R, P66
   Pollak AN, 2010, J BONE JOINT SURG AM, V92A, P7, DOI 10.2106/JBJS.H.00984
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Windolf J, 2005, TRAUMA BERUFSKRANKH, V7, pS100, DOI 10.1007/s10039-004-0917-2
   Zalavras CG, 2005, INFECT DIS CLIN N AM, V19, P915, DOI 10.1016/j.idc.2005.08.001
NR 15
TC 1
Z9 1
U1 0
U2 5
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0177-5537
EI 1433-044X
J9 UNFALLCHIRURG
JI Unfallchirurg
PD JUL
PY 2015
VL 118
IS 7
BP 643
EP 646
DI 10.1007/s00113-014-2659-3
PG 4
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA CM9JY
UT WOS:000358025900020
PM 25312681
DA 2026-07-24
ER

PT J
AU Altman, I
   Lee, IH
   Burns, MR
   Rondelli, D
   Ennis, WJ
AF Altman, Igor
   Lee, Ina H.
   Burns, Matthew R.
   Rondelli, Damiano
   Ennis, William J.
TI Cakinosis Cutis Presenting in the Context of Long-Term Therapy. for
   Chronic Myeloid Leukemia: A Case Report and Review of the Literature
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Review
DE calcinosis cutis; chronic myeloid leukemia; tyrosine kinase inhibitor;
   wound
ID TYROSINE KINASE INHIBITORS; CALCINOSIS CUTIS; DASATINIB; CALCIPHYLAXIS;
   PANNICULITIS; DISEASES
AB Calcinosis cutis is a poorly understood process in which calcium salts deposit in the skin and subcutaneous tissues. Due to its multifactorial pathogenesis, several subtypes and potential etiologies have been described. Presented here is a case of bilateral pretibial calcinosis cutis in a patient on long-term tyrosine kinase inhibitor therapy for chronic myeloid leukemia. The patient initially presented with a right tibial ulceration treated with multiple surgical debridements, antibiotics, and negative pressure wound therapy. The wound was ultimately closed with a split-thickness skin graft. Relevant literature is examined and several possible mechanisms are discussed.
C1 [Altman, Igor; Lee, Ina H.; Burns, Matthew R.; Rondelli, Damiano; Ennis, William J.] Univ Illinois Hosp & Hlth Sci Syst, Coll Med, Sect Wound Healing & Tissue Repair, Dept Surg,Div Vasc Surg, Chicago, IL 60612 USA.
RP Altman, I (通讯作者)，Univ Illinois Hosp & Hlth Sci Syst, Coll Med, Sect Wound Healing & Tissue Repair, Dept Surg,Div Vasc Surg, Chicago, IL 60612 USA.
EM ialtman@uic.edu
OI Lee, Ina/0000-0002-6082-6395
CR Amitay-Laish I, 2011, DERMATOL THER, V24, P386, DOI 10.1111/j.1529-8019.2011.01431.x
   Assouline S, 2006, NEW ENGL J MED, V354, P2623, DOI 10.1056/NEJMc053425
   Boulman N, 2005, SEMIN ARTHRITIS RHEU, V34, P805, DOI 10.1016/j.semarthrit.2005.01.016
   Goyal S, 2000, BRIT J DERMATOL, V143, P1087, DOI 10.1046/j.1365-2133.2000.03853.x
   Hartmann JT, 2009, CURR DRUG METAB, V10, P470, DOI 10.2174/138920009788897975
   Johnson MA, 2005, J PANCREAS, V6, P334
   Mastruserio DN, 1999, J AM ACAD DERMATOL, V41, P295, DOI 10.1016/S0190-9622(99)70368-3
   Pavlu J, 2009, CLIN LYMPHOMA MYELOM, V9, P417, DOI 10.3816/CLM.2009.n.083
   Pugashetti R, 2011, J AM ACAD DERMATOL, V64, P296, DOI 10.1016/j.jaad.2010.01.046
   Reiter N, 2011, J AM ACAD DERMATOL, V65, P15, DOI 10.1016/j.jaad.2010.08.039
   Reiter N, 2011, J AM ACAD DERMATOL, V65, P1, DOI 10.1016/j.jaad.2010.08.038
   Requena L, 2001, J AM ACAD DERMATOL, V45, P325, DOI 10.1067/mjd.2001.114735
   Samdani A, 2006, ANN SAUDI MED, V26, P62, DOI 10.5144/0256-4947.2006.62
   Talpaz M, 2006, NEW ENGL J MED, V354, P2531, DOI 10.1056/NEJMoa055229
   Touart DM, 1998, J AM ACAD DERMATOL, V39, P527, DOI 10.1016/S0190-9622(98)70001-5
   WALSH JS, 1995, J AM ACAD DERMATOL, V33, P693, DOI 10.1016/0190-9622(95)91803-5
NR 16
TC 1
Z9 4
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD FEB
PY 2015
VL 27
IS 2
BP 20
EP 25
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CC1JY
UT WOS:000350098200003
PM 25785904
DA 2026-07-24
ER

PT J
AU Wise, J
   White, A
   Stinner, DJ
   Fergason, JR
AF Wise, Jessica
   White, Alicia
   Stinner, Daniel J.
   Fergason, John R.
TI A Unique Application of Negative Pressure Wound Therapy Used to
   Facilitate Patient Engagement in the Amputation Recovery Process
SO ADVANCES IN WOUND CARE
LA English
DT Editorial Material
DE amputation; wound; negative pressure
ID MOBILITY PREDICTOR; LIMB AMPUTEES; MENTAL-HEALTH; TRAUMA; ABILITY;
   CLOSURE
AB Amputation rates during recent military conflicts were at an all-time high, but medical treatment of those amputations and attitudes of service members to get back to duty are also surging ahead. We present the cases of an active duty rescue C130 pilot with an above-the-knee amputation and a retired army sergeant with a below-the-knee amputation. Successful rehabilitation was augmented in both cases by using negative pressure incorporated in a custom prosthetic socket to accelerate incision closure, improve self-efficacy in wound care, and self-management, ultimately leading to faster recovery times, full engagement of the rehabilitation process, and return to active duty.
C1 [Wise, Jessica] San Antonio Mil Med Ctr, Dept Orthoped, Las Vegas, NV USA.
   [White, Alicia] San Antonio Mil Med Ctr, Ctr Intrepid, Dept Veteran Affairs Phys Therapy, San Antonio, TX USA.
   [Stinner, Daniel J.] San Antonio Mil Med Ctr, US Army Inst Surg Res, Ctr Intrepid, Dept Regenerat Med & Extrem Trauma, San Antonio, TX USA.
   [Fergason, John R.] San Antonio Mil Med Ctr, Ctr Intrepid, Dept Rehabil Med, Ft Sam Houston, TX USA.
C3 Brooke Army Medical Center; Brooke Army Medical Center; Brooke Army
   Medical Center; United States Department of Defense; United States Army;
   Brooke Army Medical Center
RP Fergason, JR (通讯作者)，San Antonio Mil Med Ctr, Ctr Intrepid, Dept Rehabil Med, 3551 Roger Brooke Dr, Jbsa Ft Sam Houston, TX 78234 USA.
EM john.r.fergason.civ@mail.mil
RI Stinner, Daniel/KSM-9513-2024
OI Stinner, Daniel/0000-0002-8981-6262
CR Archer KR, 2010, ARCH PHYS MED REHAB, V91, P774, DOI 10.1016/j.apmr.2010.01.006
   Bosse MJ, 2002, NEW ENGL J MED, V347, P1924, DOI 10.1056/NEJMoa012604
   Durmus D, 2015, COMPR PSYCHIAT, V59, P45, DOI 10.1016/j.comppsych.2014.10.018
   Fuller M, 2011, PROSTHET ORTHOT INT, V35, P246, DOI 10.1177/0309364610397085
   Gailey RS, 2013, J REHABIL RES DEV, V50, P919, DOI 10.1682/JRRD.2012.05.0100
   Gailey RS, 2002, ARCH PHYS MED REHAB, V83, P613, DOI 10.1053/ampr.2002.32309
   Gajewski Donald, 2006, J Am Acad Orthop Surg, V14, pS183
   Krueger CA, 2015, INJURY, V46, P1527, DOI 10.1016/j.injury.2015.05.015
   Krueger CA, 2014, INJURY, V45, P1231, DOI 10.1016/j.injury.2014.02.008
   Krueger CA, 2012, J TRAUMA ACUTE CARE, V73, pS438, DOI 10.1097/TA.0b013e318275469c
   Lalliss SJ, 2010, J ORTHOP TRAUMA, V24, P598, DOI 10.1097/BOT.0b013e3181ec45ba
   O'Sullivan SB, 2014, PHYS REHABILITATION, P1010
   Panyi LK, 2015, ORVOSI HETILAP, V156, P1563, DOI 10.1556/650.2015.30257
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stinner DJ, 2010, J TRAUMA, V68, P1476, DOI 10.1097/TA.0b013e3181bb9a6c
   Streubel PN, 2012, J AM ACAD ORTHOP SUR, V20, P564, DOI 10.5435/JAAOS-20-09-564
   Sumpio B, 2011, WOUNDS, V23, P301
   Swiontkowski MF, 2005, YEARB ORTHOP, V87, P96
   Traballesi M, 2010, EUR J PHYS REHAB MED, V48, P613
NR 19
TC 2
Z9 2
U1 0
U2 6
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 2162-1918
EI 2162-1934
J9 ADV WOUND CARE
JI Adv. Wound Care
PD AUG
PY 2017
VL 6
IS 8
BP 253
EP 260
DI 10.1089/wound.2016.0715
PG 8
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA FC0LZ
UT WOS:000406531200001
PM 28831328
DA 2026-07-24
ER

PT J
AU Suter, KJL
   Fairweather, L
   Al-Habbal, Y
   Houli, N
   Jacobs, R
   Bui, HT
AF Suter, Katherine J. L.
   Fairweather, Luke
   Al-Habbal, Yayha
   Houli, Nezor
   Jacobs, Rodney
   Bui, Hai T.
TI How to isolate a high output enteroatmospheric fistula in the open
   abdomen with negative pressure therapy: an institution's step by step
   guide to the VAC donut
SO ANZ JOURNAL OF SURGERY
LA English
DT Article
DE enteroatmospheric fistula; fistula donut; negative pressure wound
   therapy; open abdomen; VAC donut
ID WOUND THERAPY; MANAGEMENT; SEPSIS
AB There is multiple evidence to suggest that isolation techniques of high output enteroatmospheric fistulas (EAF) in open abdomens can be advantageous in controlling fistula effluent while allowing time for abdominal wall to granulate. The large loss of proteins, electrolytes and fluid, and the distressing nature of the open abdomen for both patients and doctors, make managing these EAFs a clinical challenge. We present our experience with a high output mucosal protruding EAF and the creation of a 'VAC donut' allowing a successful diversion of the enteric content whilst promoting granulation of the tissue bed.
C1 [Suter, Katherine J. L.; Fairweather, Luke; Al-Habbal, Yayha; Houli, Nezor; Jacobs, Rodney; Bui, Hai T.] Western Hlth, Dept Upper Gastrointestinal & Gen Surg, Melbourne, Vic, Australia.
   [Suter, Katherine J. L.] Western Hlth, Dept Upper GI & Gen Surg, 160 Gordon St, Melbourne, Vic 3011, Australia.
C3 Western Health; Western Health
RP Suter, KJL (通讯作者)，Western Hlth, Dept Upper GI & Gen Surg, 160 Gordon St, Melbourne, Vic 3011, Australia.
EM suterkj@gmail.com
OI Suter, Katherine/0000-0003-0945-3690; Fairweather,
   Luke/0000-0002-0932-5667; jacobs, rodney/0000-0002-8757-7122
CR BERRY SM, 1994, CURR PROB SURG, V31, P474
   Bobkiewicz A, 2017, INT WOUND J, V14, P255, DOI 10.1111/iwj.12597
   Cirocchi R, 2016, J TRAUMA ACUTE CARE, V81, P575, DOI 10.1097/TA.0000000000001126
   Connolly PT, 2008, ANN SURG, V247, P440, DOI 10.1097/SLA.0b013e3181612c99
   Davis KG, 2013, SURG CLIN N AM, V93, P231, DOI 10.1016/j.suc.2012.09.009
   Erdmann D, 2001, PLAST RECONSTR SURG, V108, P2066, DOI 10.1097/00006534-200112000-00036
   Evans Laura, 2021, Crit Care Med, V49, pe1063, DOI [10.1007/s00134-021-06506-y, 10.1097/CCM.0000000000005337]
   Evenson AR, 2006, J GASTROINTEST SURG, V10, P455, DOI 10.1016/j.gassur.2005.08.001
   Girard S, 2002, AM J SURG, V184, P166, DOI 10.1016/S0002-9610(02)00916-9
   Gribovskaja-Rupp I, 2016, CLIN COLON RECT SURG, V29, P130, DOI 10.1055/s-0036-1580732
   Jacobs R, 2023, WORLD J SURG, V47, P103, DOI 10.1007/s00268-022-06768-7
   Jaguscik Rajmund, 2015, Pol Przegl Chir, V87, P522, DOI [10.1515/pjs-2015-0098, 10.1515/pjs-2015-0098]
   Jamshidi R, 2007, ARCH SURG-CHICAGO, V142, P793, DOI 10.1001/archsurg.142.8.793
   Kaushal Manish, 2004, Clin Colon Rectal Surg, V17, P79, DOI 10.1055/s-2004-828654
   Marinis A, 2013, SCAND J SURG, V102, P61, DOI 10.1177/1457496913482252
   Pepe G, 2014, EUR REV MED PHARMACO, V18, P2527
   SARFEH IJ, 1992, ARCH SURG-CHICAGO, V127, P1027
   Savl MW., 2011, FISTULA RING INTERNE
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   Schecter WP, 2009, J AM COLL SURGEONS, V209, P484, DOI 10.1016/j.jamcollsurg.2009.05.025
   Tassiopoulos AK, 1996, SURG CLIN N AM, V76, P1175, DOI 10.1016/S0039-6109(05)70505-3
   Terzi C, 2014, INT WOUND J, V11, P17, DOI 10.1111/iwj.12288
   Verhaalen A, 2010, WOUNDS, V22, P212
NR 23
TC 3
Z9 5
U1 0
U2 2
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1445-1433
EI 1445-2197
J9 ANZ J SURG
JI ANZ J. Surg.
PD MAR
PY 2023
VL 93
IS 3
BP 682
EP 686
DI 10.1111/ans.18270
EA JAN 2023
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA A6JN3
UT WOS:000912807100001
PM 36629275
OA Bronze
DA 2026-07-24
ER

PT J
AU Lender, O
   Göbölös, L
   Bajwa, G
   Bhatnagar, G
AF Lender, Olga
   Gobolos, Laszlo
   Bajwa, Gurjyot
   Bhatnagar, Gopal
TI Sternal wound infections after sternotomy: risk factors, prevention and
   management
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE cardiac surgery; risk factors for sternal wound infections; sternal
   complications; sternal wound infections; sternotomy; surgical site
   infections; treatment; wound; wound care; wound healing; wound infection
ID VACUUM-ASSISTED CLOSURE; SURGICAL SITE INFECTION; C-REACTIVE PROTEIN;
   COMPLICATIONS; SURGERY; MEDIASTINITIS; THERAPY
AB A serious complication after cardiac surgery is sternal wound infection. Although incidence rates vary worldwide, this complication raises significant concern in a certain patient demographic. This article uses risk assessment strategies to identify a high-risk patient profile and draws parallels with positive predictors in the preoperative, intraoperative and postoperative setting. It describes the complexity of sternal wound infections and highlights guidelines on detection and treatment. The optimal goal of this article is to help minimise the incidence of sternal wound complications after sternotomy by discussing recommendations for preoperative, intraoperative and postoperative preventive measures.
C1 [Lender, Olga; Gobolos, Laszlo; Bajwa, Gurjyot; Bhatnagar, Gopal] Cleveland Clin Abu Dhabi, Heart Vasc & Thorac Inst, Abu Dhabi, U Arab Emirates.
C3 Cleveland Clinic Foundation
RP Lender, O (通讯作者)，Cleveland Clin Abu Dhabi, Heart Vasc & Thorac Inst, Abu Dhabi, U Arab Emirates.
EM lendero@clevelandclinicabudhabi.ae
RI Göbölös, Laszlo/HMP-2176-2023
CR Allen KB, 2017, J THORAC CARDIOV SUR, V153, P888, DOI 10.1016/j.jtcvs.2016.10.093
   Anderson DJ, 2014, INFECT CONT HOSP EP, V35, P605, DOI 10.1086/676022
   Atkins BZ, 2011, INT WOUND J, V8, P56, DOI 10.1111/j.1742-481X.2010.00743.x
   Bashaw MA, 2019, AORN J, V109, P68, DOI 10.1002/aorn.12451
   Bejko J, 2015, J CARDIOVASC MED, V16, P134, DOI 10.2459/JCM.0000000000000025
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Biancari F, 2019, SEMIN THORAC CARDIOV, V31, P465, DOI 10.1053/j.semtcvs.2019.02.029
   Brunet A, 2020, VASC HEALTH RISK MAN, V16, P553, DOI 10.2147/VHRM.S264415
   Cappabianca G, 2006, ANN THORAC SURG, V82, P2170, DOI 10.1016/j.athoracsur.2006.06.039
   Dohmen PM, 2014, MED SCI MONITOR, V20, P1814, DOI 10.12659/MSM.891169
   Fu RH, 2016, J SURG RES, V200, P400, DOI 10.1016/j.jss.2015.07.045
   Gorlitzer M, 2013, INTERACT CARDIOV TH, V17, P515, DOI 10.1093/icvts/ivt240
   Hota P, 2018, AM J ROENTGENOL, V211, P1194, DOI 10.2214/AJR.18.19782
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   Kamiya H, 2012, INTERACT CARDIOV TH, V15, P665, DOI 10.1093/icvts/ivs293
   Kaul P, 2017, J CARDIOTHORAC SURG, V12, DOI 10.1186/s13019-017-0656-7
   Kim DH, 2009, CIRC J, V73, P872, DOI 10.1253/circj.CJ-08-1010
   Listewnik MJ, 2019, ADV CLIN EXP MED, V28, P933, DOI 10.17219/acem/94154
   Listewnik MJ, 2015, ADV CLIN EXP MED, V24, P643, DOI 10.17219/acem/28111
   Loladze G, 2017, THORAC CARDIOV SURG, V65, P332, DOI 10.1055/s-0036-1582257
   Nenna A, 2019, GEN THORAC CARDIOVAS, V67, P907, DOI 10.1007/s11748-019-01204-5
   Nikolaidis N, 2013, ANN THORAC CARDIOVAS, V19, P330, DOI 10.5761/atcs.nm.12.01947
   Patel AN, 2016, J CARDIOTHORAC SURG, V11, DOI 10.1186/s13019-016-0452-9
   Phoon PHY, 2020, J CARDIOTHOR VASC AN, V34, P1602, DOI 10.1053/j.jvca.2019.09.019
   Rashed A., 2018, THESIS
   Rashed A, 2018, J THORAC DIS, V10, P3568, DOI 10.21037/jtd.2018.06.20
   Rashed A, 2018, J THORAC DIS, V10, P2412, DOI 10.21037/jtd.2018.03.166
   Rupprecht Leopold, 2013, Open J Cardiovasc Surg, V6, P9, DOI 10.4137/OJCS.S11199
   Sajja LR, 2015, INT J SURG, V16, P171, DOI 10.1016/j.ijsu.2014.11.017
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Schimmer C, 2008, ANN THORAC SURG, V86, P1897, DOI 10.1016/j.athoracsur.2008.08.071
   Schiraldi L, 2019, ARCH PLAST SURG-APS, V46, P291, DOI 10.5999/aps.2018.01151
   Sharif M, 2019, HEART LUNG CIRC, V28, P835, DOI 10.1016/j.hlc.2019.01.008
   Spindler N, 2020, SURG INFECT, V21, P370, DOI 10.1089/sur.2018.300
   Srivastava V, 2015, INTERACT CARDIOV TH, V21, P699, DOI 10.1093/icvts/ivv238
   Tam DY, 2018, ANN THORAC SURG, V106, P298, DOI 10.1016/j.athoracsur.2018.02.043
   Vos RJ, 2018, J HOSP INFECT, V100, P411, DOI 10.1016/j.jhin.2018.05.026
   Vos RJ, 2012, INTERACT CARDIOV TH, V14, P17, DOI 10.1093/icvts/ivr049
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Yu AW, 2013, INTERACT CARDIOV TH, V17, P861, DOI 10.1093/icvts/ivt326
NR 40
TC 3
Z9 6
U1 1
U2 12
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD JUN
PY 2022
VL 31
IS 6
SU S
BP S22
EP S30
DI 10.12968/jowc.2022.31.Sup6.S22
PG 9
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 2D1ZT
UT WOS:000811354600004
PM 35678775
DA 2026-07-24
ER

PT J
AU Wedemeyer, J
   Memming, M
   Schmidt, M
AF Wedemeyer, J.
   Memming, M.
   Schmidt, M.
TI Endoskopische Therapie der osophagusleckage
SO ENDOSKOPIE HEUTE
LA German
DT Article
DE osophagus; Endo-VAC; OTSC; Anastomosenleckage; selbstexpandierender
   Stent; selfexpanding stent; OTSC; anastomotic leakage; Endo-VAC;
   esophagus
ID VACUUM-ASSISTED CLOSURE; POSTOPERATIVE ESOPHAGEAL LEAKS; EXPANDING
   PLASTIC STENTS; ENDOSCOPIC CLOSURE; ANASTOMOTIC LEAKS; METAL STENTS;
   PERFORATIONS; SYSTEM; OTSC
AB Postsurgical leakages after resections of the esophagus are associated with high morbidity and mortality. Endoscopic therapy has gained increasingly acceptance and has almost completely replaced surgical revision. Placement of self expanding stents is the best established endoscopic treatment option for esophageal leakages. A new development is the endoscopic placement of vacuum sponge systems. Which have been adapted from VAC therapy for extensive infected skin defects. The development of over the scope clips (OTSC) provides another endoscopic treatment modality for esophageal leaks. Comprehensive knowledge of the various methods and their advantages as well as their limitations and drawbacks is necessary to provide optimal endoscopic care in these critically situations.
C1 [Wedemeyer, J.; Schmidt, M.] KRH Klinikum Robert Koch Gehrden, Med Klin 1, Schwerpunkt Gastroenterol & Hepatol, D-30989 Gehrden, Germany.
   [Memming, M.] KRH Klinikum Robert Koch Gehrden, D-30989 Gehrden, Germany.
RP Wedemeyer, J (通讯作者)，KRH Klinikum Robert Koch Gehrden, Med Klin 1, Schwerpunkt Gastroenterol & Hepatol, Von Reden Str 1, D-30989 Gehrden, Germany.
EM jochen.wedemeyer@krh.eu
CR Bludau M, 2013, SURG ENDOSC
   Böhm G, 2010, ENDOSCOPY, V42, P599, DOI 10.1055/s-0029-1244165
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Briel JW, 2004, J AM COLL SURGEONS, V198, P536, DOI 10.1016/j.jamcollsurg.2003.11.026
   Dai YY, 2009, BRIT J SURG, V96, P887, DOI 10.1002/bjs.6648
   David EA, 2011, AM J SURG, V202, P796, DOI 10.1016/j.amjsurg.2011.06.042
   Doniec JM, 2003, ENDOSCOPY, V35, P652
   El Hajj II, 2013, GASTROINTEST ENDOSC
   Fähndrich M, 2011, Z GASTROENTEROL, V49, P579, DOI 10.1055/s-0029-1245871
   Gubler C, 2014, SCAND J GASTROENTERO, V49, P23, DOI 10.3109/00365521.2013.850735
   Heits N, 2014, ANN THORAC SURG, DOI 10.1016/j.athoracsur.2013.11.014
   Hoeppner J, 2014, SURG ENDOSC
   Holle G, 2007, UNFALLCHIRURG, V110, P490, DOI 10.1007/s00113-007-1267-x
   Hünerbein M, 2004, ANN SURG, V240, P801, DOI 10.1097/01.sla.0000143122.76666.ae
   Langer FB, 2005, ANN THORAC SURG, V79, P398, DOI 10.1016/j.athoracsur.2004.07.006
   Lenzen H, 2013, WORLD J GASTROINTEST, V16, P340
   Pohl J, 2010, ENDOSCOPY, V42, P757, DOI 10.1055/s-0030-1255634
   Schniewind B, 2013, SURG ENDOSC, V27, P3883, DOI 10.1007/s00464-013-2998-0
   Schorsch T, 2013, SURG ENDOSC, V27, P2040, DOI 10.1007/s00464-012-2707-4
   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
   Weiland T, 2013, SURG ENDOSC, V27, P2258, DOI 10.1007/s00464-012-2754-x
   Wilson JL, 2013, J GASTROINTEST SURG, V17, P2045, DOI 10.1007/s11605-013-2357-4
NR 22
TC 0
Z9 0
U1 0
U2 1
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0933-811X
EI 1439-2577
J9 ENDOSKOPIE HEUTE
JI Endoskopie Heute
PD MAR
PY 2014
VL 27
IS 1
BP 17
EP 21
DI 10.1055/s-0034-1366189
PG 5
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA AE0HK
UT WOS:000333644300004
DA 2026-07-24
ER

PT J
AU Bogart, L
AF Bogart, L
TI A Summary of Posters Presented at the Symposium on Advanced Wound Care:
   2003 and 2004 (Reprinted from Ostomy Wound Management, vol 51, pg 88-91,
   2005)
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Reprint
AB Poster topics and study designs presented at the 2003 and 2004 Symposium on Advanced Wound Care were summarized and compared to gain insight into current wound care developments and trends. The percentage of product-related posters increased from 54% in 2003 to 76.5% in 2004. The greatest increase was observed in the so-called physical treatment modalities category (eg, vacuum-assisted closure, electrical stimulation). They represented 11% of poster topics in 2003 compared to more than 25% in 2004. The proportion of laboratory research studies presented decreased from 25% to 10% of posters while the percentage of clinical case studies increased from 40% to 50%. These observations may provide useful information to clinicians and manufacturers.
EM lbogart2@comcast.net
CR Bogart Larry, 2005, Ostomy Wound Manage, V51, P88
NR 1
TC 0
Z9 0
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2005
VL 17
IS 4
BP A38
EP +
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 921IU
UT WOS:000228758600008
DA 2026-07-24
ER

PT J
AU Cuniolo, L
   Gipponi, M
   Murelli, F
   Depaoli, F
   Cornacchia, C
   Franchelli, S
   Pesce, M
   Ronda, E
   Picardi, S
   Diaz, R
   Poggio, F
   Friedman, D
   De Cian, F
   Fregatti, P
AF Cuniolo, Letizia
   Gipponi, Marco
   Murelli, Federica
   Depaoli, Francesca
   Cornacchia, Chiara
   Franchelli, Simonetta
   Pesce, Marianna
   Ronda, Elena
   Picardi, Stefano
   Diaz, Raquel
   Poggio, Francesca
   Friedman, Daniele
   De Cian, Franco
   Fregatti, Piero
TI Multidisciplinary and Tailored Treatment of Locally Advanced Breast
   Cancer in Progression during Neoadjuvant Chemotherapy: Case Report
SO CURRENT ONCOLOGY
LA English
DT Article
DE locally advanced breast cancer (LABC); progressive disease (PD); salvage
   treatment (ST)
ID VACUUM-ASSISTED CLOSURE; SINGLE-INSTITUTION; WOUND THERAPY; TRIAL;
   RECONSTRUCTION; MASTECTOMY; PRESSURE
AB Locally advanced breast cancer (LABC) is a complex disease that requires a multidisciplinary approach. Neoadjuvant chemotherapy (NAC) is usually performed in order to achieve loco-regional radical resection; although its importance in the multidisciplinary approach to LABC is well recognized, a small number of patients show Progressive Disease (PD). No standard salvage treatment (ST) has been defined and different strategies can be adopted, such as second-line systemic therapies, radiation therapy, and surgery. Herein, a case of LABC in PD during NAC is reported with a literature review, with the aim of highlighting the importance of a tailored multidisciplinary treatment for each patient.
C1 [Cuniolo, Letizia; Murelli, Federica; Ronda, Elena; Picardi, Stefano; Diaz, Raquel; Friedman, Daniele; De Cian, Franco; Fregatti, Piero] Univ Genoa, Sch Med, Dept Surg Sci & Integrated Diagnost DISC, I-16132 Genoa, Italy.
   [Gipponi, Marco; Murelli, Federica; Depaoli, Francesca; Cornacchia, Chiara; Franchelli, Simonetta; Pesce, Marianna; Friedman, Daniele; De Cian, Franco; Fregatti, Piero] IRCCS Osped Policlin San Martino, Breast Surg Unit, I-16132 Genoa, Italy.
   [Poggio, Francesca] IRCCS Osped Policlin San Martino, Dept Med Oncol, UO Oncol Med 2, I-16132 Genoa, Italy.
C3 University of Genoa; University of Genoa; IRCCS AOU San Martino IST;
   University of Genoa; IRCCS AOU San Martino IST
RP Cuniolo, L; Fregatti, P (通讯作者)，Univ Genoa, Sch Med, Dept Surg Sci & Integrated Diagnost DISC, I-16132 Genoa, Italy.; Fregatti, P (通讯作者)，IRCCS Osped Policlin San Martino, Breast Surg Unit, I-16132 Genoa, Italy.
EM letiziacuniolo@gmail.com; marco.gipponi@hsanmartino.it;
   piero.fregatti@unige.it
RI ; Fregatti, Piero/AAL-5699-2021; MURELLI, FEDERICA/AAA-7207-2021; Ronda,
   Elena/E-6956-2012
OI Diaz, Raquel/0000-0001-5764-6804; Fregatti, Piero/0000-0002-1279-5299;
   MURELLI, FEDERICA/0000-0002-3227-4423; Cuniolo,
   Letizia/0009-0003-3826-874X
CR Ali HR, 2011, BREAST CANCER RES, V13, DOI 10.1186/bcr3061
   An JS, 2021, INT J MOL SCI, V22, DOI 10.3390/ijms22179644
   Bonnefoi H, 2014, ANN ONCOL, V25, P1128, DOI 10.1093/annonc/mdu118
   Caudle AS, 2010, J CLIN ONCOL, V28, P1821, DOI 10.1200/JCO.2009.25.3286
   Cortazar P, 2014, LANCET, V384, P164, DOI 10.1016/S0140-6736(13)62422-8
   Eginton MT, 2003, ANN VASC SURG, V17, P645, DOI 10.1007/s10016-003-0065-3
   ESO, 2020, ESMO International Consensus Guidelines for Advanced Breast Cancer ABC5
   Galli G, 2017, BREAST CARE, V12, P391, DOI 10.1159/000479582
   Gianni L, 2010, LANCET, V375, P377, DOI 10.1016/S0140-6736(09)61964-4
   Joseph E, 2000, WOUNDS, V12, P60
   King TA, 2015, NAT REV CLIN ONCOL, V12, P335, DOI 10.1038/nrclinonc.2015.63
   Korde LA, 2021, J CLIN ONCOL, V39, P1485, DOI 10.1200/JCO.20.03399
   Lindström LS, 2018, JNCI-J NATL CANCER I, V110, P726, DOI 10.1093/jnci/djx270
   Ma CX, 2015, NAT REV CANCER, V15, P261, DOI 10.1038/nrc3920
   Masuda N, 2017, NEW ENGL J MED, V376, P2147, DOI 10.1056/NEJMoa1612645
   Monrigal E, 2011, EJSO-EUR J SURG ONC, V37, P864, DOI 10.1016/j.ejso.2011.07.009
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mouës CM, 2007, J PLAST RECONSTR AES, V60, P672, DOI 10.1016/j.bjps.2006.01.041
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Paillocher N, 2016, EJSO-EUR J SURG ONC, V42, P949, DOI 10.1016/j.ejso.2016.03.024
   Petrelli F, 2016, ANTI-CANCER DRUG, V27, P702, DOI 10.1097/CAD.0000000000000369
   Raphael J, 2017, BREAST CANCER RES TR, V163, P11, DOI 10.1007/s10549-017-4167-y
   Rastogi P, 2008, J CLIN ONCOL, V26, P778, DOI 10.1200/JCO.2007.15.0235
   Roininen N, 2017, OXID MED CELL LONGEV, V2017, DOI 10.1155/2017/2908039
   Rugo HS, 2015, J CLIN ONCOL, V33, P2361, DOI 10.1200/JCO.2014.59.5298
   Santa-Maria CA, 2015, ONCOLOGY-NY, V29, P828
   Spring LM, 2020, CLIN CANCER RES, V26, P2838, DOI 10.1158/1078-0432.CCR-19-3492
   Symmans WF, 2007, J CLIN ONCOL, V25, P4414, DOI 10.1200/JCO.2007.10.6823
   Touboul E, 1996, INT J RADIAT ONCOL, V34, P1019, DOI 10.1016/0360-3016(95)02207-4
   Tryfonidis K, 2015, NAT REV CLIN ONCOL, V12, P147, DOI 10.1038/nrclinonc.2015.13
   von Minckwitz G, 2012, J CLIN ONCOL, V30, P1796, DOI 10.1200/JCO.2011.38.8595
   Whitman GJ, 2009, SEMIN RADIAT ONCOL, V19, P211, DOI 10.1016/j.semradonc.2009.05.006
   Zattarin E, 2020, CELLS-BASEL, V9, DOI 10.3390/cells9122644
NR 33
TC 5
Z9 6
U1 0
U2 0
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
SN 1198-0052
EI 1718-7729
J9 CURR ONCOL
JI Curr. Oncol.
PD MAY
PY 2024
VL 31
IS 5
BP 2856
EP 2866
DI 10.3390/curroncol31050217
PG 11
WC Oncology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology
GA SJ7J6
UT WOS:001234148900001
PM 38785498
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Hinck, D
   Struve, R
   Gatzka, F
   Schürmann, G
AF Hinck, D
   Struve, R
   Gatzka, F
   Schürmann, G
TI Vacuum-assisted fascial closure in the management of diffuse peritonitis
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nurnberg, GERMANY
DE peritonitis; vacuum-assisted closure; laparostomy; abdominal compartment
   syndrome
ID LAVAGE
AB The surgical treatment of patients suffering from peritonitis with an open abdomen is commonplace. However scheduled as well as required dressing changes and peritoneal lavages mean a time- and costs-intensive challenge for the nursing and medical personnel. Since the introduction of the abdominal dressing-kit (KCI(R), Walluf, Germany) in the management of diffuse peritonitis one expects to influence the patients' recovery in a positive way due to the continuous evacuation of intraabdominal infectious fluids, augmentation of tissue's granulation, prevention of fascial retraction and prevention of an abdominal compartment syndrome. First on trial we established 2004 in our surgical department the use of the abdominal dressing-kit as a routine procedure in the management of diffuse peritonitis.
C1 Bundeswehrkrankenhaus Hamburg, Abt Allgemein Thorax & Viszeralchirurg, D-22049 Hamburg, Germany.
   Klinikum Itzehoe, Klin Allgemein Gefass & Viszeralchirurg, Itzehoe, Germany.
RP Hinck, D (通讯作者)，Bundeswehrkrankenhaus Hamburg, Abt Allgemein Thorax & Viszeralchirurg, Lesserstr 180, D-22049 Hamburg, Germany.
EM d.hinck@t-online.de
OI Hinck, Daniel/0000-0002-1226-4244
CR Kirschner M, 1926, ARCH KLIN CHIR, V142, P253
   MCKENNA JP, 1970, SURG GYNECOL OBSTETR, V130, P254
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   PETER FW, 1989, ZBL CHIR, V114, P844
   PICHLMAYR R, 1983, CHIRURG, V54, P299
   Schächter L, 2000, REV SCI INSTRUM, V71, P918, DOI 10.1063/1.1150345
   TEICHMANN W, 1983, CHIRURG BEHANDLUNG P, P62
   WALSH GL, 1988, SURG CLIN N AM, V68, P25
   Wild T, 2004, ZBL CHIR, V129, pS20, DOI 10.1055/s-2004-822651
   WITTMANN D, 1986, HOECHST MONOGRAPHI A
NR 10
TC 6
Z9 6
U1 0
U2 0
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S108
EP S110
DI 10.1055/s-2006-921447
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 034DB
UT WOS:000236904100025
PM 16575658
DA 2026-07-24
ER

PT J
AU Hollins, AW
   Mithani, SK
AF Hollins, Andrew W.
   Mithani, Suhail K.
TI Advances in Soft Tissue Injuries Associated with Open Fractures
SO HAND CLINICS
LA English
DT Article
DE Soft tissue; Flap reconstruction; Traumatic wounds; Grafts
ID FLEXOR CARPI ULNARIS; LATERAL ARM FLAP; VACUUM-ASSISTED CLOSURE; RADIAL
   FOREARM FLAP; PRESSURE WOUND THERAPY; ANCONEUS MUSCLE FLAP; EXTERNAL
   FIXATION; ARTIFICIAL SKIN; GROIN FLAP; THIGH FLAP
AB There are many options for solving complex upper extremity soft tissue defects in the setting of underlying fractures. Understanding the patient's injuries and exposed structures is critical for selecting the appropriate reconstruction. DRT has allowed for a bridging of many wounds that are not amenable to skin graft coverage. If a flap is required for coverage, the defect size and location are the greatest factors for the appropriate operative treatment. Often times, multiple options are available for reconstruction and the decision must be made in conjunction with the patient for each specific clinical encounter.
C1 [Hollins, Andrew W.] Duke Univ Med Ctr, Dept Surg, Div Plast Surg, Box 3974 Duke Med Ctr, Durham, NC 27710 USA.
   [Mithani, Suhail K.] Duke Univ Med Ctr, Dept Surg, Div Plast Surg, 2301 Erwin Rd, Durham, NC 27710 USA.
   [Mithani, Suhail K.] North Carolina Orthopaed Clin, 3609 Southwest Durham Dr, Durham, NC 27707 USA.
C3 Duke University; Duke University
RP Mithani, SK (通讯作者)，North Carolina Orthopaed Clin, 3609 Southwest Durham Dr, Durham, NC 27707 USA.
EM suhail.mithani@duke.edu
RI Mithani, Suhail/LBH-9657-2024
OI Mithani, Suhail/0000-0002-3762-0831; Hollins, Anew/0000-0003-2879-4618
CR Abdelrahman M, 2018, MICROSURG, V38, P458, DOI 10.1002/micr.30238
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Avashia YJ, 2018, PLAST RECONSTR SURG, V142, P152, DOI 10.1097/PRS.0000000000004472
   Bhattacharyya T, 2008, PLAST RECONSTR SURG, V121, P1263, DOI 10.1097/01.prs.0000305536.09242.a6
   Brogan DM, 2015, J HAND SURG-AM, V40, P1905, DOI 10.1016/j.jhsa.2015.03.014
   BURKE JF, 1981, ANN SURG, V194, P413, DOI 10.1097/00000658-198110000-00005
   Calotta NA, 2020, J RECONSTR MICROSURG, V36, P680, DOI 10.1055/s-0040-1714149
   Capo JT, 2009, J HAND SURG-AM, V34A, P1605, DOI 10.1016/j.jhsa.2009.07.010
   Cardany C MP, 1992, Pedicle flaps of the upper limb. The antecubital forearm flap
   Chen SL, 2004, BRIT J PLAST SURG, V57, P525, DOI 10.1016/j.bjps.2004.04.018
   Cherubino M, 2017, J RECONSTR MICROSURG, V33, pS8, DOI 10.1055/s-0037-1606542
   CHOW JA, 1986, PLAST RECONSTR SURG, V77, P421, DOI 10.1097/00006534-198603000-00014
   Di Giuli R, 2021, ANN PLAS SURG, V86, P655, DOI 10.1097/SAP.0000000000002777
   Elhassan B, 2011, J SHOULDER ELB SURG, V20, P807, DOI 10.1016/j.jse.2011.02.010
   Federer AE, 2020, PLAST RECONSTR SURG, V146, p420E, DOI 10.1097/PRS.0000000000007156
   Frame JD, 2004, PLAST RECONSTR SURG, V113, P1330, DOI 10.1097/01.PRS.0000111883.93604.85
   FREELAND AE, 1988, HAND CLIN, V4, P425
   Goodman AD, 2017, J HAND SURG-AM, V42, P456, DOI 10.1016/j.jhsa.2017.03.028
   Hennerbichler A, 2003, CLIN ANAT, V16, P204, DOI 10.1002/ca.10140
   Jordan SW, 2015, ANN PLAS SURG, V74, P30, DOI 10.1097/SAP.0b013e3182853f0b
   Kamrani RS, 2018, J SHOULDER ELB SURG, V27, P435, DOI 10.1016/j.jse.2017.09.018
   Kang YQ, 2020, J ORTHOP SURG RES, V15, DOI 10.1186/s13018-020-01647-0
   King EA, 2014, HAND CLIN, V30, P201, DOI 10.1016/j.hcl.2014.01.003
   Kocman EA, 2021, MICROSURG, V41, P430, DOI 10.1002/micr.30746
   Kokkalis ZT, 2019, EUR J ORTHOP SURG TR, V29, P279, DOI 10.1007/s00590-019-02363-0
   Kreulen M, 2008, J BIOMECH, V41, P2130, DOI 10.1016/j.jbiomech.2008.04.030
   KUEK LBK, 1991, J RECONSTR MICROSURG, V7, P167, DOI 10.1055/s-2007-1006775
   Lateo SA, 2013, CLIN EXP DERMATOL, V38, P606, DOI 10.1111/ced.12044
   Lee KT, 2014, PLAST RECONSTR SURG, V134, P303, DOI 10.1097/PRS.0000000000000365
   Lesiak AC, 2013, J HAND SURG-AM, V38A, P1828, DOI 10.1016/j.jhsa.2013.04.029
   Lingaraj K, 2007, CLIN ORTHOP RELAT R, P262, DOI 10.1097/01.blo.0000238780.19692.5f
   Liu J, 2021, HEAD NECK-J SCI SPEC, V43, P467, DOI 10.1002/hed.26506
   Martin-Playa P, 2019, CLIN PLAST SURG, V46, P275, DOI 10.1016/j.cps.2019.02.001
   McGregor I A, 1972, Br J Plast Surg, V25, P3
   Morrison CS, 2013, ANN PLAS SURG, V71, P37, DOI 10.1097/SAP.0b013e318248b627
   Müller-Seubert W, 2021, J PLAST RECONSTR AES, V74, P2527, DOI 10.1016/j.bjps.2021.02.007
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Okamoto S, 2014, CASE REP SURG, V2014, DOI 10.1155/2014/798506
   Orbay J, 2005, HAND CLIN, V21, P347, DOI 10.1016/j.hcl.2005.02.003
   Pagnotta A, 2012, J HAND SURG-AM, V37A, P2605, DOI 10.1016/j.jhsa.2012.09.004
   Payne DES, 2011, J HAND SURG-AM, V36A, P246, DOI 10.1016/j.jhsa.2010.10.035
   Qu ZG, 2012, CHIN J TRAUMATOL, V15, P352, DOI 10.3760/cma.j.issn.1008-1275.2012.06.007
   Richardson D, 1997, PLAST RECONSTR SURG, V99, P109, DOI 10.1097/00006534-199701000-00017
   Rinker B, 2013, ANN PLAS SURG, V70, P599, DOI 10.1097/SAP.0b013e3182764fcd
   Robinson LP, 2021, PLAST RECONSTR SURG, V148, P1316, DOI 10.1097/PRS.0000000000008578
   Rogachefsky RA, 2002, ORTHOPEDICS, V25, P403
   Ruch DS, 2015, J SHOULDER ELB SURG, V24, P236, DOI 10.1016/j.jse.2014.09.035
   Ruta D, 2013, HAND CLIN, V29, P551, DOI 10.1016/j.hcl.2013.08.008
   Satteson ES, 2017, J RECONSTR MICROSURG, V33, P544, DOI 10.1055/s-0037-1602740
   Schmidt CC, 1999, J HAND SURG-AM, V24A, P359
   Seth AK, 2017, J RECONSTR MICROSURG, V33, P466, DOI 10.1055/s-0037-1601422
   Sharma K, 2018, J HAND SURG-AM, V43, P105, DOI 10.1016/j.jhsa.2017.11.003
   Sharpe F, 2014, J SHOULDER ELB SURG, V23, P82, DOI 10.1016/j.jse.2013.07.057
   Shores JT, 2012, J PLAST RECONSTR AES, V65, P1544, DOI 10.1016/j.bjps.2012.05.021
   SONG RY, 1982, CLIN PLAST SURG, V9, P27
   SONG YG, 1984, BRIT J PLAST SURG, V37, P149, DOI 10.1016/0007-1226(84)90002-X
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Sundine M, 1996, J HAND SURG-BRIT EUR, V21B, P216, DOI 10.1016/S0266-7681(96)80102-1
   Tansini P., 1908, Lancet, V171, P634
   Vetter M, 2010, J RECONSTR MICROSURG, V26, P455, DOI 10.1055/s-0030-1254229
   Wang Howard T, 2004, Tech Hand Up Extrem Surg, V8, P257, DOI 10.1097/00130911-200412000-00009
   WEBER SC, 1986, J HAND SURG-AM, V11A, P157, DOI 10.1016/S0363-5023(86)80045-4
   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
   Williksen JH, 2013, J HAND SURG-AM, V38A, P1469, DOI 10.1016/j.jhsa.2013.04.039
   Wong CH, 2010, HEAD NECK-J SCI SPEC, V32, P529, DOI 10.1002/hed.21204
   WRAY RC, 1982, ANN PLAS SURG, V9, P459, DOI 10.1097/00000637-198212000-00002
   Yajima H, 1999, J HAND SURG-AM, V24A, P594
   Yang GF, 1997, BRIT J PLAST SURG, V50, P162, DOI 10.1016/S0007-1226(97)91363-1
   Yang Z, 2020, ANN PLAS SURG, V84, pS165, DOI 10.1097/SAP.0000000000002372
   ZANCOLLI EA, 1988, J HAND SURG-BRIT EUR, V13B, P130, DOI 10.1016/0266-7681(88)90121-0
NR 70
TC 0
Z9 1
U1 0
U2 2
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0749-0712
EI 1558-1969
J9 HAND CLIN
JI Hand Clin.
PD NOV
PY 2023
VL 39
IS 4
BP 605
EP 616
DI 10.1016/j.hcl.2023.05.008
EA OCT 2023
PG 12
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA X5PS4
UT WOS:001098974700001
PM 37827613
DA 2026-07-24
ER

PT J
AU Connolly, TP
AF Connolly, TP
TI Necrotizing surgical site infection after tension-free vaginal tape
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Article
ID OBESE PATIENTS; SURGERY
AB BACKGROUND: Infectious morbidity after tension-free vaginal tape (FVT) treatment of urinary stress incontinence may be a potential concern.
   CASE: A 53-year-old obese woman with a 7-year history of urinary incontinence consented to TVT placement. Two days after discharge the patient presented with suspected cellulitis. Dicloxacillin, ciprofloxacin, ampicillin/sulbactam, and metronidazole were ineffective. Removal of the tape, surgical debridement, dressing changes, ceftriaxone, and clindamycin followed by levofloxacin and metronidazole, repeat wound debridement, and vacuum assisted closure were required. Frozen section revealed gangrenous soft tissue with areas of skin necrosis, but no fasciitis.
   CONCLUSION: This is the first case of necrotizing surgical site infection after TVT placement. Infectious morbidity risks need to be considered in these procedures. (C) 2004 by The American College of Obstetricians and Gynecologists.
C1 Wausau Ctr, Marshfield Clin, Dept Obstet & Gynecol, Wausau, WI 54401 USA.
C3 Marshfield Clinic
RP Connolly, TP (通讯作者)，Wausau Ctr, Marshfield Clin, Dept Obstet & Gynecol, 2727 Plaza Dr, Wausau, WI 54401 USA.
EM connolly.thomas@marshfieldclinic.org
CR FORSE RA, 1989, SURGERY, V106, P750
   Gallup DG, 2002, AM J OBSTET GYNECOL, V187, P305, DOI 10.1067/mob.2002.126000
   Kuuva N, 2002, ACTA OBSTET GYN SCAN, V81, P72, DOI 10.1034/j.1600-0412.2002.810113.x
   MANDELL GS, 1999, PRINCIPLES PRACTICE, P1061
   Mukherjee K, 2001, BJU INT, V88, P881, DOI 10.1046/j.1464-4096.2001.01653.x
   NYSTROM PO, 1987, ACTA CHIR SCAND, V153, P225
   Ulmsten U, 1996, Int Urogynecol J Pelvic Floor Dysfunct, V7, P81, DOI 10.1007/BF01902378
NR 7
TC 23
Z9 28
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0029-7844
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD DEC
PY 2004
VL 104
IS 6
BP 1275
EP 1276
DI 10.1097/01.AOG.0000146284.62793.8f
PG 2
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA 878YL
UT WOS:000225683400012
PM 15572489
DA 2026-07-24
ER

PT J
AU Yusuf, E
   Chan, M
   Renz, N
   Trampuz, A
AF Yusuf, Erlangga
   Chan, Monica
   Renz, Nora
   Trampuz, Andrej
TI Current perspectives on diagnosis and management of sternal wound
   infections
SO INFECTION AND DRUG RESISTANCE
LA English
DT Review
DE deep sternal wound infection; diagnosis; antibiotic; surgical treatment
ID SURGICAL-SITE INFECTIONS; CARDIAC-SURGERY PATIENTS; VACUUM-ASSISTED
   CLOSURE; OPEN-HEART-SURGERY; RISK-FACTORS; STAPHYLOCOCCUS-AUREUS;
   POSTOPERATIVE MEDIASTINITIS; POSTSTERNOTOMY MEDIASTINITIS; MORTALITY;
   FOSFOMYCIN
AB Deep sternal wound infection (DSWI), also known as mediastinitis, is a serious and potentially fatal condition. The diagnosis and treatment of DSWI are challenging. In this current narrative review, the epidemiology, risk factors, diagnosis, and surgical and antimicrobial management of DSWI are discussed. Ideally, the management of DSWI requires early and sufficient surgical debridement and appropriate antibiotic therapy. When foreign material is present, biofilm-active antibiotic therapy is also needed. Because DSWI is often complex, the management requires the involvement of a multidisciplinary team consisting of cardiothoracic surgeons, plastic surgeons, intensivists, infectious disease specialists, and clinical microbiologists.
C1 [Yusuf, Erlangga] Univ Antwerp, Dept Med Microbiol, Antwerp Univ Hosp UZA, Antwerp, Belgium.
   [Chan, Monica] Tan Tock Seng Hosp, Dept Infect Dis, Singapore, Singapore.
   [Renz, Nora; Trampuz, Andrej] Charite Univ Med Berlin, Berlin, Germany.
   [Renz, Nora; Trampuz, Andrej] Humboldt Univ, Freie Univ Berlin, Berlin, Germany.
   [Renz, Nora; Trampuz, Andrej] Berlin Inst Hlth, Ctr Musculoskeletal Surg CMSC, Berlin, Germany.
C3 University of Antwerp; Tan Tock Seng Hospital; Free University of
   Berlin; Humboldt University of Berlin; Charite Universitatsmedizin
   Berlin; Free University of Berlin; Humboldt University of Berlin;
   Humboldt University of Berlin; Free University of Berlin; Charite
   Universitatsmedizin Berlin; Berlin Institute of Health
RP Yusuf, E (通讯作者)，Univ Antwerp, Dept Microbiol, Antwerp Univ Hosp UZA, Wilrijkstr 10, B-2650 Edegem, Belgium.
EM angga.yusuf@gmail.com
RI Yusuf, Erlangga/H-5166-2019
OI Yusuf, Erlangga/0000-0003-4779-2191
CR Abboud CS, 2004, ANN THORAC SURG, V77, P676, DOI 10.1016/S0003-4975(03)01523-6
   Abu-Omar Y, 2017, EUR J CARDIO-THORAC, V51, P10, DOI 10.1093/ejcts/ezw326
   Akman C, 2004, CLIN RADIOL, V59, P573, DOI 10.1016/j.crad.2003.12.001
   ALVAREZ S, 1985, ANTIMICROB AGENTS CH, V28, P689, DOI 10.1128/AAC.28.5.689
   Ariyaratnam P, 2010, INTERACT CARDIOV TH, V11, P543, DOI 10.1510/icvts.2010.237883
   Atkins BZ, 2011, AM J SURG, V202, P565, DOI 10.1016/j.amjsurg.2011.06.013
   Baldo B.A. e., 2013, Drug Allergy. Clinical Aspects, Diagnosis, Mechanisms
   Berdajs DA, 2011, INTERACT CARDIOV TH, V12, P914, DOI 10.1510/icvts.2010.263483
   Birgand G, 2013, INTERACT CARDIOV TH, V16, P134, DOI 10.1093/icvts/ivs449
   Bode LGM, 2010, NEW ENGL J MED, V362, P9, DOI 10.1056/NEJMoa0808939
   BOR DH, 1983, REV INFECT DIS, V5, P885
   Borger MA, 1998, ANN THORAC SURG, V65, P1050, DOI 10.1016/S0003-4975(98)00063-0
   Brunet F, 1996, J THORAC CARDIOV SUR, V111, P1200
   Chan M, 2016, DIAGN MICR INFEC DIS, V84, P261, DOI 10.1016/j.diagmicrobio.2015.11.011
   Charbonneau H, 2014, CLIN MICROBIOL INFEC, V20, pO197, DOI 10.1111/1469-0691.12369
   Chaudhuri A, 2012, EUR J CARDIO-THORAC, V41, P1304, DOI 10.1093/ejcts/ezr239
   Chen LF, 2012, AM J INFECT CONTROL, V40, P963, DOI 10.1016/j.ajic.2012.01.012
   Cimochowski GE, 2001, ANN THORAC SURG, V71, P1572, DOI 10.1016/S0003-4975(01)02519-X
   Combes A, 2004, CLIN INFECT DIS, V38, P822, DOI 10.1086/381890
   Cotogni Paolo, 2015, World J Crit Care Med, V4, P265, DOI [10.5492/wjccm.v4.i4.265, 10.5492/wjccm.v4.i4.265]
   Cutrell JB, 2016, AM J INFECT CONTROL, V44, P1302, DOI 10.1016/j.ajic.2016.03.027
   De Feo M, 2001, ANN THORAC SURG, V71, P324, DOI 10.1016/S0003-4975(00)02137-8
   De Feo Marisa, 2011, Asian Cardiovasc Thorac Ann, V19, P39, DOI 10.1177/0218492310395789
   Edwards FH, 2006, ANN THORAC SURG, V81, P397, DOI 10.1016/j.athoracsur.2005.06.034
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Engelman R, 2007, ANN THORAC SURG, V83, P1569, DOI 10.1016/j.athoracsur.2006.09.046
   Floros P, 2011, HEART LUNG CIRC, V20, P712, DOI 10.1016/j.hlc.2011.08.001
   Force SD, 2005, ANN THORAC SURG, V80, P618, DOI 10.1016/j.athoracsur.2005.02.056
   Friberg Ö, 2007, EUR J CLIN MICROBIOL, V26, P91, DOI 10.1007/s10096-006-0252-6
   Gårdlund B, 2002, EUR J CARDIO-THORAC, V21, P825, DOI 10.1016/S1010-7940(02)00084-2
   HORAN TC, 1992, INFECT CONT HOSP EP, V13, P606
   Horan TC, 2008, AM J INFECT CONTROL, V36, P309, DOI 10.1016/j.ajic.2008.03.002
   Johnson B, 2012, AM J CASE REP, V13, P86, DOI 10.12659/AJCR.882856
   Jolles H, 1996, RADIOLOGY, V201, P463, DOI 10.1148/radiology.201.2.8888241
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   Juhl AA, 2012, SCAND CARDIOVASC J, V46, P254, DOI 10.3109/14017431.2012.674549
   Khanlari B, 2010, J ANTIMICROB CHEMOTH, V65, P1799, DOI 10.1093/jac/dkq182
   Kowalewski M, 2015, J THORAC CARDIOV SUR, V149, P1631, DOI 10.1016/j.jtcvs.2015.01.034
   KUBOTA H, 2013, J CARDIOTHORAC SURG, V8
   Lazar HL, 2016, J THORAC CARDIOV SUR, V152, P962, DOI 10.1016/j.jtcvs.2016.01.060
   Lazar HL, 2014, J THORAC CARDIOV SUR, V148, P1035, DOI 10.1016/j.jtcvs.2014.06.045
   Mihailescu R, 2014, ANTIMICROB AGENTS CH, V58, P2547, DOI 10.1128/AAC.02420-12
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Omran AS, 2007, BMC INFECT DIS, V7, DOI 10.1186/1471-2334-7-112
   Read C, 2015, J PLAST RECONSTR AES, V68, P1132, DOI 10.1016/j.bjps.2015.04.027
   Ridderstolpe L, 2001, EUR J CARDIO-THORAC, V20, P1168, DOI 10.1016/S1010-7940(01)00991-5
   Robicsek F, 2000, AM SURGEON, V66, P184
   Roussos N, 2009, INT J ANTIMICROB AG, V34, P506, DOI 10.1016/j.ijantimicag.2009.08.013
   Sakamoto Hiroaki, 2003, Ann Thorac Cardiovasc Surg, V9, P226
   Schintler MV, 2009, J ANTIMICROB CHEMOTH, V64, P574, DOI 10.1093/jac/dkp230
   Sears ED, 2016, WORLD J SURG, V40, P2673, DOI 10.1007/s00268-016-3598-7
   Singh Kimberly, 2011, Semin Plast Surg, V25, P25, DOI 10.1055/s-0031-1275168
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Tegnell A, 2000, ANN THORAC SURG, V69, P1104, DOI 10.1016/S0003-4975(99)01563-5
   Wang FD, 2000, J CARDIOVASC SURG, V41, P709
   Yusuf E, 2017, PRINCIPLES ORTHOPEDI
   Yusuf E, 2013, WOUND REPAIR REGEN, V21, P677, DOI 10.1111/wrr.12088
   Zimmerli W, 2004, NEW ENGL J MED, V351, P1645, DOI 10.1056/NEJMra040181
NR 58
TC 36
Z9 51
U1 0
U2 5
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
SN 1178-6973
J9 INFECT DRUG RESIST
JI Infect. Drug Resistance
PY 2018
VL 11
BP 961
EP 968
DI 10.2147/IDR.S130172
PG 8
WC Infectious Diseases; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Pharmacology & Pharmacy
GA GN6KC
UT WOS:000439190200001
PM 30038509
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Passera, E
   Rizzi, A
   Robustellini, M
   Rossi, G
   Della Pona, C
   Massera, F
   Rocco, G
AF Passera, Eliseo
   Rizzi, Adriano
   Robustellini, Mario
   Rossi, Gerolamo
   Della Pona, Claudio
   Massera, Fabio
   Rocco, Gaetano
TI Pulmonary Aspergilloma Clinical Aspects and Surgical Treatment Outcome
SO THORACIC SURGERY CLINICS
LA English
DT Article
DE Aspergilloma; Pulmonary mycetoma; Tuberculosis; Hemoptysis; Fungal
   infections; Thoracic surgery
ID OPEN-WINDOW THORACOSTOMY; VACUUM-ASSISTED CLOSURE; COMPLEX ASPERGILLOMA;
   MASSIVE HEMOPTYSIS; TOPICAL TREATMENT; PLEURAL EMPYEMA; SURGERY;
   MANAGEMENT; EXPERIENCE; RESECTION
AB Aspergillomas are fungal balls within lung cavities. The natural history is variable. Hemoptysis is a dangerous sequela. Medical therapy is ineffective because of the lack of a lesion blood supply. Randomized trials are lacking. Surgery should be the treatment of choice in cases of hemoptysis, and even in asymptomatic patients, if lung function is not severely compromised. Cavernostomy and cavernoplasty may be options for high-risk patients. Percutaneous therapy should be reserved for patients who are not fit for surgery. Bronchial artery embolization is appropriate for symptomatic patients not suitable for surgery. Embolization could be considered a preoperative and temporary strategy.
C1 [Passera, Eliseo; Rizzi, Adriano] Humanitas Gavazzeni Hosp, Div Thorac Surg, I-24123 Bergamo, Italy.
   [Robustellini, Mario; Della Pona, Claudio] E Morelli Hosp, Div Thorac Surg, I-23039 Sondalo, Italy.
   [Rossi, Gerolamo] Valduce Hosp, Div Thorac Surg, I-22100 Como, Italy.
   [Massera, Fabio] Maggiore Carita Hosp, Div Thorac Surg, I-28100 Novara, Italy.
   [Rocco, Gaetano] Natl Canc Inst, Pascale Fdn, Dept Thorac Surg & Oncol, Div Thorac Surg, I-80131 Naples, Italy.
C3 Istituto Clinico Humanitas Gavazzeni; IRCCS Fondazione Pascale
RP Passera, E (通讯作者)，Humanitas Gavazzeni Hosp, Div Thorac Surg, Via Gavazzeni 21, I-24123 Bergamo, Italy.
EM eliseo.passera@gavazzeni.it
RI Rocco, Gaetano/K-4801-2016
OI Rocco, Gaetano/0000-0003-4150-8604
CR Akbari JG, 2005, ANN THORAC SURG, V80, P1067, DOI 10.1016/j.athoracsur.2005.03.078
   Alexander J, 1937, COLLAPSE THEORY PULM
   ALMAJED SA, 1990, THORAX, V45, P846, DOI 10.1136/thx.45.11.846
   [Anonymous], 1970, Tubercle, V51, P227
   [Anonymous], TUBERCLE
   Aru GM, 2010, ANN THORAC SURG, V90, P266, DOI 10.1016/j.athoracsur.2010.04.092
   Babatasi G, 2000, J THORAC CARDIOV SUR, V119, P906, DOI 10.1016/S0022-5223(00)70085-7
   BATTAGLINI JW, 1985, ANN THORAC SURG, V39, P512, DOI 10.1016/S0003-4975(10)61986-8
   BELCHER JR, 1960, BRIT J DIS CHEST, V54, P335, DOI 10.1016/S0007-0971(60)80067-8
   Bonesio L, 2011, VILLAGGIO MORELLI ID, P54
   BORELLI D, 1979, POSTGRAD MED J, V55, P657, DOI 10.1136/pgmj.55.647.657
   BREUER R, 1982, J COMPUT ASSIST TOMO, V6, P166, DOI 10.1097/00004728-198202000-00029
   Brik A, 2008, EUR J CARDIO-THORAC, V34, P882, DOI 10.1016/j.ejcts.2008.06.049
   Buckingham SJ, 2003, EUR RADIOL, V13, P1786, DOI 10.1007/s00330-002-1813-4
   Caidi M, 2006, PRESSE MED, V35, P1819, DOI 10.1016/S0755-4982(06)74907-7
   Cesar JMS, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-129
   Chatzimichalis A, 1998, ANN THORAC SURG, V65, P927, DOI 10.1016/S0003-4975(98)00060-5
   Chen JC, 1997, THORAX, V52, P810, DOI 10.1136/thx.52.9.810
   Csekeo A, 1997, EUR J CARDIO-THORAC, V12, P876, DOI 10.1016/S1010-7940(97)00272-8
   DALY RC, 1986, J THORAC CARDIOV SUR, V92, P981
   DEGREGORIO MW, 1982, AM J MED, V73, P543, DOI 10.1016/0002-9343(82)90334-5
   Demir Adalet, 2006, Asian Cardiovasc Thorac Ann, V14, P407
   Dobbertin I, 2010, Pneumologie, V64, P171, DOI 10.1055/s-0029-1215306
   EIN ME, 1979, AM REV RESPIR DIS, V119, P811
   ElOakley R, 1997, THORAX, V52, P813, DOI 10.1136/thx.52.9.813
   Falkson C, 2002, CLIN ONCOL-UK, V14, P233, DOI 10.1053/clon.2002.0063
   FAULKNER SL, 1978, ANN THORAC SURG, V25, P389, DOI 10.1016/S0003-4975(10)63570-9
   Franquet T, 2001, RADIOGRAPHICS, V21, P825, DOI 10.1148/radiographics.21.4.g01jl03825
   García-Yuste M, 1998, ANN THORAC SURG, V65, P818, DOI 10.1016/S0003-4975(97)01386-6
   GARVEY J, 1977, J THORAC CARDIOV SUR, V74, P542
   HAMMERMAN KJ, 1973, CHEST, V64, P697, DOI 10.1378/chest.64.6.697
   HINSON KFW, 1952, THORAX, V7, P317, DOI 10.1136/thx.7.4.317
   HUGHES CF, 1986, THORAX, V41, P324, DOI 10.1136/thx.41.4.324
   Ichinose J, 2010, INTERACT CARDIOV TH, V10, P927, DOI 10.1510/icvts.2009.232066
   JEWKES J, 1983, THORAX, V38, P572, DOI 10.1136/thx.38.8.572
   KARAS A, 1976, ANN THORAC SURG, V22, P1, DOI 10.1016/S0003-4975(10)63943-4
   Kim YT, 2005, ANN THORAC SURG, V79, P294, DOI 10.1016/j.athoracsur.2004.05.050
   Lee JG, 2009, J THORAC CARDIOV SUR, V138, P820, DOI 10.1016/j.jtcvs.2009.01.019
   Lejay A, 2011, INTERACT CARDIOV TH, V13, P392, DOI 10.1510/icvts.2011.265553
   LIPINSKI JK, 1978, J CAN ASSOC RADIOL, V29, P216
   MASSARD G, 1992, ANN THORAC SURG, V54, P1159, DOI 10.1016/0003-4975(92)90086-J
   Massard G, 1996, ANN THORAC SURG, V62, P1033, DOI 10.1016/0003-4975(96)00596-6
   Massera F, 2009, ANN THORAC SURG, V87, P869, DOI 10.1016/j.athoracsur.2008.12.003
   MONALDI V, 1968, SCAND J RESPIR DIS, VS, P113
   Musher B, 2004, J CLIN MICROBIOL, V42, P5517, DOI 10.1128/JCM.42.12.5517-5522.2004
   Palmen M, 2009, ANN THORAC SURG, V88, P1131, DOI 10.1016/j.athoracsur.2009.06.030
   Park CK, 2002, EUR J CARDIO-THORAC, V21, P918, DOI 10.1016/S1010-7940(02)00104-5
   PECORA DV, 1960, NEW ENGL J MED, V263, P785, DOI 10.1056/NEJM196010202631605
   Pennington James E., 1993, P133
   PENNINGTON JE, 1983, RESPIRATORY INFECTIO, P329
   PERSONNE C, 1979, REV FR MAL RESPIR, V7, P43
   RAFFERTY P, 1983, THORAX, V38, P579, DOI 10.1136/thx.38.8.579
   Regnard JF, 2000, ANN THORAC SURG, V69, P898, DOI 10.1016/S0003-4975(99)01334-X
   REMY J, 1973, NOUV PRESSE MED, V2, P2060
   REMY J, 1992, P667
   RIZZI A, 1995, ANN THORAC SURG, V59, P896, DOI 10.1016/0003-4975(95)00011-9
   ROCCO G, 1994, ANN THORAC SURG, V57, P260, DOI 10.1016/0003-4975(94)90425-1
   Rocco G, 2012, EUR J CARDIO-THORAC, V41, P1069, DOI 10.1093/ejcts/ezr196
   Rumbak M, 1996, THORAX, V51, P253, DOI 10.1136/thx.51.3.253
   Sagan D, 2010, ANN THORAC SURG, V89, P1603, DOI 10.1016/j.athoracsur.2010.02.037
   SHAPIRO MJ, 1988, CHEST, V94, P1225, DOI 10.1378/chest.94.6.1225
   Sharma OP, 1998, EUR RESPIR J, V12, P705, DOI 10.1183/09031936.98.12030705
   Shiraishi Y, 2006, EUR J CARDIO-THORAC, V29, P9, DOI 10.1016/j.ejcts.2005.10.043
   Shiraishi Y, 2004, ANN THORAC SURG, V78, P399, DOI 10.1016/j.athoracsur.2004.02.103
   SHIRAKUSA T, 1989, ANN THORAC SURG, V48, P779, DOI 10.1016/0003-4975(89)90670-X
   STAMATIS G, 1988, THORAC CARDIOV SURG, V36, P356, DOI 10.1055/s-2007-1022981
   Stefani A, 2011, ANN THORAC SURG, V91, P263, DOI 10.1016/j.athoracsur.2010.07.084
   UFLACKER R, 1983, RADIOLOGY, V146, P627, DOI 10.1148/radiology.146.3.6828674
   Walsh TJ, 2008, CLIN INFECT DIS, V46, P327, DOI 10.1086/525258
   YAMADA H, 1993, CHEST, V103, P1421, DOI 10.1378/chest.103.5.1421
   Yoon W, 2002, RADIOGRAPHICS, V22, P1395, DOI 10.1148/rg.226015180
   YOUNG VK, 1992, ANN THORAC SURG, V53, P621, DOI 10.1016/0003-4975(92)90321-T
NR 72
TC 30
Z9 37
U1 0
U2 8
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1547-4127
J9 THORAC SURG CLIN
JI Thorac. Surg. Clin.
PD AUG
PY 2012
VL 22
IS 3
BP 345
EP +
DI 10.1016/j.thorsurg.2012.04.001
PG 18
WC Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System; Surgery
GA 047TH
UT WOS:000311863900009
PM 22789598
DA 2026-07-24
ER

PT J
AU Norbury, K
   Kieswetter, K
AF Norbury, Kenneth
   Kieswetter, Kris
TI Vacuum-assisted closure therapy attenuates the inflammatory response in
   a porcine acute wound healing model
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID TUMOR-NECROSIS-FACTOR; VASCULAR-DISEASE; GROWTH-FACTORS; T-LYMPHOCYTES;
   CYTOKINES; MICE; EXPRESSION; REPAIR; TISSUE; IL-6
AB Porcine full-thickness wounds were treated with V.A.C.(R) Therapy (KCI, San Antonio, Tex) or moist wound dressing without negative pressure. V.A.C. Therapy related systemic effects included post-wound reduction in the number of peripheral blood monocytes and neutrophils during the inflammatory phase of wound healing, as well as reduced serum levels of the pro-inflammatory cytokines IFN-gamma and IL-6. Local effects included reduced concentrations of IL-8, TGF-beta 1, and TNF-alpha in wound fluid following V.A.C. Therapy. Collectively, these responses suggest that V.A.C. Therapy may attenuate the pro-inflammatory response following cutaneous wounding.
C1 Kinet Concepts Inc, San Antonio, TX 78249 USA.
RP Norbury, K (通讯作者)，Kinet Concepts Inc, 6203 Farinon Dr, San Antonio, TX 78249 USA.
EM norburyk@kci1.com
CR ADAMS TST, 2003, EUR TISS RES SOC FOC, P212
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Badier-Commander C, 2000, J PATHOL, V192, P105, DOI 10.1002/1096-9896(2000)9999:9999<::AID-PATH670>3.0.CO;2-1
   BANWELL PE, 2003, EUR TISS REP SOC TNP
   Barton BE, 1997, CLIN IMMUNOL IMMUNOP, V85, P16, DOI 10.1006/clin.1997.4420
   BELARDELLI F, 1995, APMIS, V103, P161, DOI 10.1111/j.1699-0463.1995.tb01092.x
   Bennett D, 2002, PLAST SURG RES COUNC
   Breuing K, 1997, PLAST RECONSTR SURG, V100, P657, DOI 10.1097/00006534-199709000-00018
   Charo IF, 2004, CIRC RES, V95, P858, DOI 10.1161/01.RES.0000146672.10582.17
   COICO R, 2003, IMMUNOLOGY, P149
   Davidson JM, 2001, WOUNDS, V13, P9
   Dovi JV, 2004, THROMB HAEMOSTASIS, V92, P275, DOI 10.1160/TH03-11-0720
   Dovi JV, 2003, J LEUKOCYTE BIOL, V73, P448, DOI 10.1189/jlb.0802406
   DUBRAVEC DB, 1990, P NATL ACAD SCI USA, V87, P6758, DOI 10.1073/pnas.87.17.6758
   Fujiwara Nagatoshi, 2005, Current Drug Targets - Inflammation and Allergy, V4, P281, DOI 10.2174/1568010054022024
   Gallucci RM, 2000, FASEB J, V14, P2525, DOI 10.1096/fj.00-0073com
   Goodman G J, 2001, Australas J Dermatol, V42, P84
   Gottrup F, 2000, WOUND REPAIR REGEN, V8, P83, DOI 10.1046/j.1524-475x.2000.00083.x
   Graves DT, 2001, J IMMUNOL, V167, P5316, DOI 10.4049/jimmunol.167.9.5316
   Hack CE, 1997, ADV IMMUNOL, V66, P101, DOI 10.1016/S0065-2776(08)60597-0
   Hamilton JA, 2004, GROWTH FACTORS, V22, P225, DOI 10.1080/08977190412331279881
   Henry G, 2003, SURG CLIN N AM, V83, P483, DOI 10.1016/S0039-6109(02)00200-1
   Jacob CI, 2001, J AM ACAD DERMATOL, V45, P109, DOI 10.1067/mjd.2001.113451
   Joseph E, 2000, WOUNDS, V12, P60
   Kilpadi D, 2006, WOUND REPAIR REGEN, V14, P210, DOI 10.1111/j.1743-6109.2006.00112.x
   KILPADI DV, 2006, WOUND HEAL SOC ANN M
   KISHIMOTO T, 1989, BLOOD, V74, P1, DOI 10.1182/blood.V74.1.1.1
   Kitamura M, 1997, NEPHROL DIAL TRANSPL, V12, P669, DOI 10.1093/ndt/12.4.669
   KLEBANOFF SJ, 1986, J IMMUNOL, V136, P4220
   KREMERS L, 2003, AM BURN ASS M MIAM F
   KUMAR S, 2004, TURK J MED SCI, V3, P147
   LEIBOVICH SJ, 1975, AM J PATHOL, V78, P71
   Lenhoff S, 1999, EXP HEMATOL, V27, P410, DOI 10.1016/S0301-472X(98)00060-5
   Lin ZQ, 2003, J LEUKOCYTE BIOL, V73, P713, DOI 10.1189/jlb.0802397
   Lu B, 1998, J EXP MED, V187, P601, DOI 10.1084/jem.187.4.601
   Luster AD, 1998, NEW ENGL J MED, V338, P436, DOI 10.1056/NEJM199802123380706
   Mast Bruce A., 1996, Wound Repair and Regeneration, V4, P411, DOI 10.1046/j.1524-475X.1996.40404.x
   McCallon S K, 2000, Ostomy Wound Manage, V46, P28
   Montero-Julian FA, 2001, CELL MOL BIOL, V47, P583
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   NORBURY K, 2005, WOUND HEAL SOC M CHI
   Omoigui S, 2005, MED HYPOTHESES, V65, P559, DOI 10.1016/j.mehy.2005.03.012
   Pirone L., 1990, WOUNDS, V2, P74
   Roberts AW, 2005, GROWTH FACTORS, V23, P33, DOI 10.1080/08977190500055836
   Sandler NG, 2003, J IMMUNOL, V171, P3655, DOI 10.4049/jimmunol.171.7.3655
   Schultz G, 1994, ACUTE CHRONIC WOUNDS, P413
   Schultz GS, 2003, WOUND REPAIR REGEN, V11, pS1, DOI 10.1046/j.1524-475X.11.s2.1.x
   Stechmiller JK, 2006, WOUND REPAIR REGEN, V14, P371, DOI 10.1111/j.1743-6109.2006.00134.x
   Suh D Y, 1998, Clin Podiatr Med Surg, V15, P1
   Sullivan TP, 2001, WOUND REPAIR REGEN, V9, P66, DOI 10.1046/j.1524-475x.2001.00066.x
   Tarnuzzer Roy W., 1996, Wound Repair and Regeneration, V4, P321, DOI 10.1046/j.1524-475X.1996.40307.x
   TAUB DD, 1995, J CLIN INVEST, V95, P1370, DOI 10.1172/JCI117788
   VANWIJCK R, 2002, EUR TISS REP SOC M N
   WAHL SM, 1994, J EXP MED, V180, P1587, DOI 10.1084/jem.180.5.1587
   Wilgus TA, 2003, WOUND REPAIR REGEN, V11, P25, DOI 10.1046/j.1524-475X.2003.11106.x
   WYSOCKI AB, 1993, J INVEST DERMATOL, V101, P64, DOI 10.1111/1523-1747.ep12359590
   Yao F, 2001, WOUND REPAIR REGEN, V9, P371, DOI 10.1046/j.1524-475x.2001.00371.x
NR 58
TC 26
Z9 33
U1 0
U2 7
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD APR
PY 2007
VL 19
IS 4
BP 97
EP 106
PG 10
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 164RW
UT WOS:000246252700005
PM 26110258
DA 2026-07-24
ER

PT J
AU Tsang, CLN
   Gunanayagam, P
   Feitosa, R
   Villalba, L
AF Tsang, Chi Lap Nicholas
   Gunanayagam, Prashanth
   Feitosa, Rui
   Villalba, Laurencia
TI High Output Chylous Fistula Post First Rib Resection
SO ANNALS OF VASCULAR SURGERY
LA English
DT Article
ID LYMPH-NODE DISSECTION; THORACIC-DUCT; MANAGEMENT; LEAK
AB We present a patient who developed high output chyle leak post left first-rib resection for neurogenic thoracic outlet syndrome. The persistent high output chylorrhea was refractory to 3 surgical reexplorations attempting to ligate leaking branches, bed rest, nonfat diet, parenteral nutrition, octreotide administration, and vacuum-assisted closure (VAC) therapy. In addition, she developed hypovolemia, hyponatremia, and hypoalbuminemia. Control of the chylous fistula was achieved by reattaching the sternocleidomastoid muscle laterally to protect the phrenic nerve and brachial plexus in order to redirect chyle to the medial portion of the neck incision site. This was supported by the application of fibrin sealants in combination with VAC therapy. The patient was discharged after a 27-day hospital stay with complete resolution of her chylous fistula prior to discharge.
C1 [Tsang, Chi Lap Nicholas; Gunanayagam, Prashanth; Feitosa, Rui; Villalba, Laurencia] Wollongong Hosp, Dept Surg, Wollongong, NSW, Australia.
   [Tsang, Chi Lap Nicholas; Villalba, Laurencia] Univ Wollongong, Grad Sch Med, Wollongong, NSW, Australia.
C3 Wollongong Hospital; University of Wollongong
RP Tsang, CLN (通讯作者)，Wollongong Hosp, Dept Surg, Wollongong, NSW, Australia.
EM ncltsang@gmail.com
OI Tsang, Chi Lap Nicholas/0000-0002-7503-469X; Villalba,
   Laurencia/0000-0002-3143-6785
CR Brennan PA, 2012, BRIT J ORAL MAX SURG, V50, P197, DOI 10.1016/j.bjoms.2011.02.001
   Campisi CC, 2013, CURR OPIN OTOLARYNGO, V21, P150, DOI 10.1097/MOO.0b013e32835e9d97
   Cheng L, 2014, BRIT J ORAL MAX SURG, V52, P87, DOI 10.1016/j.bjoms.2013.09.007
   CHENG SWK, 1994, J VASC SURG, V19, P565, DOI 10.1016/S0741-5214(94)70027-3
   Delaney SW, 2017, INT J OTOLARYNGOL, V2017
   Desai SS, 2014, ANN VASC SURG, V28, P457, DOI 10.1016/j.avsg.2013.02.029
   Dorneden A, 2019, ANN OTO RHINOL LARYN, V128, P569, DOI 10.1177/0003489419827037
   Giove E, 2010, ANN ITAL CHIR, V81, P361
   Hempel GK, 1996, ANN VASC SURG, V10, P456, DOI 10.1007/BF02000592
   Ilczyszyn A, 2011, J PLAST RECONSTR AES, V64, pE223, DOI 10.1016/j.bjps.2010.12.018
   Jain A, 2015, LARYNGOSCOPE, V125, P1624, DOI 10.1002/lary.25171
   Kannan R R, 2001, Indian J Cancer, V38, P117
   Kirse DJ, 1997, OTOLARYNG HEAD NECK, V116, P680, DOI 10.1016/S0194-5998(97)70249-3
   Lisan Q, 2014, Rev Laryngol Otol Rhinol (Bord), V135, P141
   Otero MJL, 2010, NUTR HOSP, V25, P1041, DOI 10.3305/nh.2010.25.6.4802
   LUCENTE FE, 1981, OTOLARYNG HEAD NECK, V89, P575, DOI 10.1177/019459988108900413
   Park I, 2018, HEAD NECK-J SCI SPEC, V40, P7, DOI 10.1002/hed.24852
   Polistena A, 2015, INT J SURG, V21, P128, DOI 10.1016/j.ijsu.2015.07.698
   Seifert S, 2017, ZBL CHIR, V142, P104, DOI 10.1055/s-0042-121611
   Shirakawa Y, 2015, ACTA MED OKAYAMA, V69, P173
   Singh M, 2011, CLIN BREAST CANCER, V11, P320, DOI 10.1016/j.clbc.2011.04.003
   Tenny BC, 2018, INT J SURG CASE REP, V42, P7, DOI 10.1016/j.ijscr.2017.11.031
   Velegrakis GA, 1998, ORL J OTO-RHINO-LARY, V60, P230, DOI 10.1159/000027600
   WITTE CL, 1995, ACAD RADIOL, V2, P324, DOI 10.1016/S1076-6332(05)80193-X
   Zou M., 2015, BMJ CASE REP, V2015
NR 25
TC 2
Z9 2
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD FEB
PY 2020
VL 63
AR 455.e1
DI 10.1016/j.avsg.2019.07.023
PG 5
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA KK7PY
UT WOS:000512931700052
PM 31622760
DA 2026-07-24
ER

PT J
AU Nolff, MC
   Meyer-Lindenberg, A
AF Nolff, Mirja Christine
   Meyer-Lindenberg, Andrea
TI Therapy of open wounds in small animal medicine - an overview of modern
   wound dressings
SO KLEINTIERPRAXIS
LA German
DT Article
DE open wound treatment; wound healing; moist wound healing; modern wound
   dressings
ID VACUUM-ASSISTED CLOSURE; THICKNESS SKIN WOUNDS; NEGATIVE-PRESSURE;
   OCCLUSIVE DRESSINGS; MANAGEMENT; GRANULATION; BANDAGES; GROWTH; CAT; GEL
AB The treatment of open wounds is a daily challenge in veterinary medicine. There are numerous different wound dressings available, but unfortunately only a few have been tested regarding their effectivity in dogs and cats. Due to this non-transparent situation on the market combined with a lack of veterinary studies, the choice of an appropriate wound dressing is frequently based on empirical experience rather than on funded knowledge. This article provides an overview of the general requirements to be met by modern wound dressings and the current knowledge of their effectiveness in dogs and cats.
C1 [Nolff, Mirja Christine; Meyer-Lindenberg, Andrea] Univ Munich, Chirurg & Gynakol Kleintierklin, Vet Str 13, D-80539 Munich, Germany.
C3 University of Munich
RP Nolff, MC (通讯作者)，Univ Munich, Chirurg & Gynakol Tierklin, Vet Str 13, D-80539 Munich, Germany.
EM m.nolff@lmu.de
RI Nolff, Mirja/W-6756-2019; Meyer-Lindenberg, Andreas/H-1076-2011
CR Abramo F, 2008, AUST VET J, V86, P95, DOI 10.1111/j.1751-0813.2007.00243.x
   Adkesson MJ, 2007, JAVMA-J AM VET MED A, V231, P1249, DOI 10.2460/javma.231.8.1249
   Assadian O, 2010, INT WOUND J, V7, P283, DOI 10.1111/j.1742-481X.2010.00686.x
   Ben-Amotz R, 2007, VET SURG, V36, P684, DOI 10.1111/j.1532-950X.2007.00321.x
   Bertran J, 2013, J SMALL ANIM PRACT, V54, P381, DOI 10.1111/jsap.12055
   Bohling MW, 2004, VET SURG, V33, P579, DOI 10.1111/j.1532-950X.2004.04081.x
   Bolton LL, 2000, OSTOMY WOUND MANAG, V46, P51
   Bristow PC, 2013, JAVMA-J AM VET MED A, V243, P863, DOI 10.2460/javma.243.6.863
   Campbell BG, 2006, VET CLIN N AM-SMALL, V36, P759, DOI 10.1016/j.cvsm.2006.03.002
   Coutin JV, 2015, VET SURG, V44, P9, DOI 10.1111/j.1532-950X.2014.12218.x
   Demaria M, 2011, VET SURG, V40, P658, DOI 10.1111/j.1532-950X.2011.00849.x
   Eaglstein WH, 2001, DERMATOL SURG, V27, P175, DOI 10.1046/j.1524-4725.2001.00299.x
   Fahie MA, 2007, VET CLIN N AM-SMALL, V37, P559, DOI 10.1016/j.cvsm.2007.02.001
   García-Cardeña G, 2001, P NATL ACAD SCI USA, V98, P4478, DOI 10.1073/pnas.071052598
   Gemeinhardt KD, 2005, EQUINE VET EDUC, V17, P27, DOI 10.1111/j.2042-3292.2005.tb00331.x
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   Guille AE, 2007, JAVMA-J AM VET MED A, V230, P1669, DOI 10.2460/javma.230.11.1669
   Hadley HS, 2013, VET SURG, V42, P161, DOI 10.1111/j.1532-950X.2012.01048.x
   Horn T, 2012, UNFALLCHIRURG, V115, P774, DOI 10.1007/s00113-012-2209-9
   Howe LM, 2015, VET CLIN N AM-SMALL, V45, P565, DOI 10.1016/j.cvsm.2015.01.005
   Huang S, 2000, EXP CELL RES, V261, P91, DOI 10.1006/excr.2000.5044
   Ichioka S, 2008, WOUND REPAIR REGEN, V16, P460, DOI 10.1111/j.1524-475X.2008.00390.x
   Jacobs S, 2009, J PLAST RECONSTR AES, V62, P1331, DOI 10.1016/j.bjps.2008.03.024
   Jee CH, 2015, J VET SCI
   Karayannopoulou M, 2015, VET COMP ORTHOPAED, V28, P172, DOI 10.3415/VCOT-14-06-0088
   Kilpadi D, 2006, WOUND REPAIR REGEN, V14, P210, DOI 10.1111/j.1743-6109.2006.00112.x
   Lafortune M, 2007, J ZOO WILDLIFE MED, V38, P341, DOI 10.1638/1042-7260(2007)038[0341:WMIAJT]2.0.CO;2
   Lalliss SJ, 2010, J ORTHOP TRAUMA, V24, P598, DOI 10.1097/BOT.0b013e3181ec45ba
   MORGAN PW, 1994, VET SURG, V23, P494, DOI 10.1111/j.1532-950X.1994.tb00511.x
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Mullally C, 2010, J VET EMERG CRIT CAR, V20, P456, DOI 10.1111/j.1476-4431.2010.00564.x
   Nolff MC, 2015, J SMALL ANIM PRACT, V56, P281, DOI 10.1111/jsap.12275
   Nolff MC, 2015, SCHWEIZ ARCH TIERH, V157, P105, DOI 10.17236/sat00009
   Nolff MC, 2015, VET COMP ORTHOPAED, V28, P30, DOI 10.3415/VCOT-14-05-0076
   Nolff MC, 2015, J FELINE MED SURG, V17, P1041, DOI 10.1177/1098612X15569893
   Or M, 2015, VET COMP ORTHOPAED, V28, P140, DOI 10.3415/VCOT-14-04-0056
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Owen LJ, 2009, VET COMP ORTHOPAED, V22, P417, DOI 10.3415/VCOT-08-12-0123
   Pavletic M, 1993, ATLAS SMALL ANIMAL R, P11
   Pitt KA, 2014, VET SURG, V43, P380, DOI 10.1111/j.1532-950X.2014.12155.x
   Pitzer GB, 2011, FACIAL PLAST SURG CL, V19, P491, DOI 10.1016/j.fsc.2011.06.012
   RAMSEY DT, 1995, AM J VET RES, V56, P941
   Röcken F, 2012, KLEINTIERPRAXIS, V57, P542, DOI 10.2377/0023-2076-57-542
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Seaman S, 2002, J AM PODIAT MED ASSN, V92, P24, DOI 10.7547/87507315-92-1-24
   Stahl J, 2010, INT WOUND J, V7, P62, DOI 10.1111/j.1742-481X.2009.00648.x
   Swaim SF, 2000, AM J VET RES, V61, P1574, DOI 10.2460/ajvr.2000.61.1574
   Tambella AM, 2014, VET SURG, V43, P726, DOI 10.1111/j.1532-950X.2014.12148.x
   Thompson G., 2008, BR J COMMUNITY NURS, V13, P23
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Weese JS, 2008, VET COMP ORTHOPAED, V21, P1, DOI 10.3415/VCOT-07-11-0106
   White RJ, 2002, PROF NURSE, V18, P35
   Wilson J, 2001, CRIT CARE NURS Q, V9, P24
   Winkler JT, 2002, VET SURG, V31, P541, DOI 10.1053/jvet.2002.34669
   WINTER GD, 1962, NATURE, V193, P293, DOI 10.1038/193293a0
   Yang Charlie C, 2006, J Surg Orthop Adv, V15, P19
NR 60
TC 0
Z9 0
U1 0
U2 45
PU M H SCHAPER GMBH CO KG
PI ALFELD
PA BORSIGSTRASSE 5, POSTFACH 16 42, 310460 ALFELD, GERMANY
SN 0023-2076
J9 KLEINTIERPRAXIS
JI Kleintierpraxis
PD MAY
PY 2016
VL 61
IS 5
BP 267
EP 277
DI 10.2377/0023-2076-61-267
PG 11
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA DN1LI
UT WOS:000376826900004
DA 2026-07-24
ER

PT J
AU Gottrup, F
   Apelqvist, J
   Price, P
AF Gottrup, F.
   Apelqvist, J.
   Price, P.
TI Outcomes in controlled and comparative studies on non-healing wounds:
   recommendations to improve the quality of evidence in wound management
SO JOURNAL OF WOUND CARE
LA English
DT Article
ID DIABETIC FOOT ULCERS; VENOUS LEG ULCERS; RANDOMIZED CONTROLLED-TRIAL;
   VACUUM-ASSISTED CLOSURE; SURROGATE END-POINTS; OF-LIFE;
   MATRIX-METALLOPROTEINASES; CLINICAL-TRIALS; LIMB ISCHEMIA; HEALING RATES
AB While there is a consensus that clinical practice should be evidence based, this can be difficult to achieve due to confusion about the value of the various approaches to wound management. To address this, the European Wound Management Association (EWMA) set up a Patient Outcome Group whose remit was to produce recommendations on clinical data collection in wound care. This document, produced by the group and disseminated by JWC, identifies criteria for producing rigorous outcomes in both randomised controlled trials and clinical studies, and describes how to ensure studies are consistent and reproducible
C1 [Gottrup, F.] Bispebjerg Hosp, EWMA Patient Outcome Grp, Copenhagen, Denmark.
   [Apelqvist, J.] Malmo Univ Hosp, Malmo, Sweden.
   [Apelqvist, J.] Lund Univ, S-22100 Lund, Sweden.
   [Price, P.] Cardiff Univ, Sch Healthcare Studies, Cardiff CF10 3AX, S Glam, Wales.
C3 University of Copenhagen; Bispebjerg Hospital; Copenhagen University
   Hospital; Lund University; Skane University Hospital; Lund University;
   Cardiff University
RP Gottrup, F (通讯作者)，Bispebjerg Hosp, EWMA Patient Outcome Grp, Copenhagen, Denmark.
CR Abetz L, 2002, PRACT DIABETES INT, V19, P167, DOI DOI 10.1002/PDI.356
   Alvarez OM, 2002, WOUNDS, V14, p5S
   [Anonymous], OSTOMY WOUND MANAGE
   [Anonymous], SHOULD ALTERNATIVE E
   [Anonymous], 2005, Methods for the Economic Evaluation of Health Care Programme
   [Anonymous], 2004, CELLULAR MOL BIOCH D
   [Anonymous], FOOT
   [Anonymous], 2006, Guidance for Industry: Chronic Cutaneous Ulcer and Burn Wounds-Developing Products for Treatment
   Armstrong DG, 2002, J AM PODIAT MED ASSN, V92, P12, DOI 10.7547/87507315-92-1-12
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Ashford R.L., 2000, DIABETIC FOOT, V3, P150
   Atkinson AJ Jr, 2001, CLIN PHARMACOL THER, V69, P89, DOI 10.1067/mcp.2000.113989
   Bahmer FA, 1999, ARCH DERMATOL, V135, P991, DOI 10.1001/archderm.135.8.991-a
   Bell-Syer S, 2009, INT WOUND J, V6, P306, DOI 10.1111/j.1742-481X.2009.00620_1.x
   Biancari F, 2007, WORLD J SURG, V31, P217, DOI 10.1007/s00268-006-0242-y
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Boulton AJM, 2005, LANCET, V366, P1719, DOI 10.1016/S0140-6736(05)67698-2
   Bouza C, 2005, WOUND REPAIR REGEN, V13, P218, DOI 10.1111/j.1067-1927.2005.130302.x
   Brazier J, 2002, J HEALTH ECON, V21, P271, DOI 10.1016/S0167-6296(01)00130-8
   Briggs M, 2006, J Wound Care, V15, P333
   BULSTRODE CJK, 1987, J ROY SOC MED, V80, P210, DOI 10.1177/014107688708000406
   Cardinal M, 2008, WOUND REPAIR REGEN, V16, P19, DOI 10.1111/j.1524-475X.2007.00328.x
   Carrington AL, 1996, DIABETES RES CLIN PR, V32, P19, DOI 10.1016/0168-8227(96)01198-9
   Carrington AL, 1995, INT CONGR SER, V1084, P159
   Chaby G, 2007, ARCH DERMATOL, V143, P1297, DOI 10.1001/archderm.143.10.1297
   Coerper S, 2009, J DIABETES COMPLICAT, V23, P49, DOI 10.1016/j.jdiacomp.2008.02.001
   Cole J, 2001, WOUND REPAIR REGEN, V9, P360, DOI 10.1046/j.1524-475x.2001.00360.x
   Cooper L, 2005, GENOME BIOL, V6
   Cukjati D, 2000, MED BIOL ENG COMPUT, V38, P339, DOI 10.1007/BF02347056
   Dale J J, 1983, Health Bull (Edinb), V41, P310
   De Gruttola VG, 2001, CONTROL CLIN TRIALS, V22, P485, DOI 10.1016/S0197-2456(01)00153-2
   Edwards R, 2004, CURR OPIN INFECT DIS, V17, P91, DOI 10.1097/00001432-200404000-00004
   Eneroth M, 1999, J DIABETES COMPLICAT, V13, P254, DOI 10.1016/S1056-8727(99)00065-3
   Falanga V, 2000, WOUND REPAIR REGEN, V8, P347
   Falanga V, 2006, DERMATOL THER, V19, P383, DOI 10.1111/j.1529-8019.2006.00096.x
   Flanagan Madeleine, 2003, Ostomy Wound Manage, V49, P28
   Fleck Cynthia A, 2006, Adv Skin Wound Care, V19, P77, DOI 10.1097/00129334-200603000-00008
   Fleming TR, 1996, ANN INTERN MED, V125, P605, DOI 10.7326/0003-4819-125-7-199610010-00011
   Franks Peter J, 2003, Ostomy Wound Manage, V49, P26
   Franks PJ, 2001, QUAL LIFE RES, V10, P693, DOI 10.1023/A:1013825924765
   Franks PJ, 2002, WOUND REPAIR REGEN, V10, P133, DOI 10.1046/j.1524-475X.2002.11002.x
   Franz MG, 2000, WOUND REPAIR REGEN, V8, P511, DOI 10.1046/j.1524-475x.2000.00511.x
   FREEDMAN LS, 1992, STAT MED, V11, P167, DOI 10.1002/sim.4780110204
   Gebski V, 2002, MED J AUSTRALIA, V176, P491, DOI 10.5694/j.1326-5377.2002.tb04522.x
   Gershater MA, 2009, DIABETOLOGIA, V52, P398, DOI 10.1007/s00125-008-1226-2
   Gethin G, 2006, J CLIN NURS, V15, P422, DOI 10.1111/j.1365-2702.2006.01364.x
   Gibran NS, 2003, METH MOLEC MED, V78, P425
   Gorin DR, 1996, J VASC SURG, V23, P524, DOI 10.1016/S0741-5214(96)80021-8
   Gottrup F, 2004, AM J SURG, V187, p38S, DOI 10.1016/S0002-9610(03)00303-9
   Gottrup F, 2009, J Wound Care, V18, P460
   Gottrup F, 2010, BRIT J SURG, V97, P303, DOI 10.1002/bjs.7030
   Gottrup F., 2009, BMJ RAPID RESPONSE
   Gottrup F., 2010, EWMA J, V10, P3
   Gottrup Finn, 2006, Int J Low Extrem Wounds, V5, P74, DOI 10.1177/1534734606288412
   Grey JE, 2009, BMJ-BRIT MED J, V338, DOI 10.1136/bmj.b1434
   Grose R, 2004, GENOME BIOL, V5, DOI 10.1186/gb-2004-5-6-228
   Haghpanah S, 2006, ARCH PHYS MED REHAB, V87, P1396, DOI 10.1016/j.apmr.2006.06.014
   HAYWARD PG, 1993, J AM GERIATR SOC, V41, P238, DOI 10.1111/j.1532-5415.1993.tb06699.x
   Hinchliffe RJ, 2008, DIABETES-METAB RES, V24, pS119, DOI 10.1002/dmrr.825
   Horkan L, 2009, J Wound Care, V18, P298
   Hyde C, 1999, Int J Nurs Pract, V5, P189
   Hyland M E, 1994, J Wound Care, V3, P294
   International Working Group on the Diabetic Foot (IWGDF), 2007, INT CONS DIAB FOOT P
   Jeffcoate WJ, 2009, HEALTH TECHNOL ASSES, V13, P1, DOI 10.3310/hta13540
   Keast DH, 2004, WOUND REPAIR REGEN, V12, pS1, DOI 10.1111/j.1067-1927.2004.0123S1.x
   Kechagias A, 2008, ANN VASC SURG, V22, P547, DOI 10.1016/j.avsg.2008.01.007
   Korber Andreas, 2006, J Dtsch Dermatol Ges, V4, P848, DOI 10.1111/j.1610-0387.2006.06113.x
   Krasner D, 1998, Ostomy Wound Manage, V44, P38
   Lagan KM, 2000, ARCH PHYS MED REHAB, V81, P1110, DOI 10.1053/apmr.2000.6281
   Langemo D K, 1998, Adv Wound Care, V11, P337
   Lavery LA, 2007, DIABETES CARE, V30, P14, DOI 10.2337/dc06-1600
   Lazareth I, 2008, WOUNDS, V20, P158
   LAZARUS GS, 1994, ARCH DERMATOL, V130, P489, DOI 10.1001/archderm.130.4.489
   Leaper D, 2009, INT WOUND J, V6, P89, DOI 10.1111/j.1742-481X.2009.00581.x
   Levine S., 2009, EFFECTIVENESS GUIDAN
   LINDHOLM C, 1993, ACTA DERM-VENEREOL, V73, P440
   Lipsky BA, 2007, J ANTIMICROB CHEMOTH, V60, P370, DOI 10.1093/jac/dkm130
   Lipsky BA, 2009, WOUND REPAIR REGEN, V17, P671, DOI 10.1111/j.1524-475X.2009.00521.x
   Little C, 2009, J Wound Care, V18, P250
   Liu P. Y., 1991, PSEF INSTRUCTIAL COU
   Lobmann R, 2002, DIABETOLOGIA, V45, P1011, DOI 10.1007/s00125-002-0868-8
   MARGOLIS DJ, 1993, J AM ACAD DERMATOL, V28, P418, DOI 10.1016/0190-9622(93)70061-W
   Matousek S, 2007, Int J Low Extrem Wounds, V6, P284, DOI 10.1177/1534734607308315
   Meaume S, 2005, J Wound Care, V14, P411
   Meijer JWG, 2001, DISABIL REHABIL, V23, P336
   Michaels JA, 2009, BRIT J SURG, V96, P1147, DOI 10.1002/bjs.6786
   Moher D, 2001, LANCET, V357, P1191, DOI 10.1016/S0140-6736(00)04337-3
   Moore K, 2005, J Wound Care, V14, P229
   Moore Keith, 2006, Int Wound J, V3, P89, DOI 10.1111/j.1742-4801.2006.00212.x
   Moses MA, 1996, J CELL BIOCHEM, V60, P379, DOI 10.1002/(SICI)1097-4644(19960301)60:3<379::AID-JCB9>3.3.CO;2-0
   Mwaura B, 2006, EUR J VASC ENDOVASC, V31, P306, DOI 10.1016/j.ejvs.2005.08.007
   O'Meara S, 2009, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD000265.pub3
   Paddock H. N., 2002, ANN M WOUND HEAL SOC
   Palfreyman S, 2007, BMJ-BRIT MED J, V335, P244, DOI 10.1136/bmj.39248.634977.AE
   Partsch H, 2008, DERMATOL SURG, V34, P600, DOI 10.1111/j.1524-4725.2007.34116.x
   Peinemann F, 2008, BMC MED RES METHODOL, V8, DOI 10.1186/1471-2288-8-4
   Penhallow K, 2005, J Wound Care, V14, P123
   Persoon A, 2004, J CLIN NURS, V13, P341, DOI 10.1046/j.1365-2702.2003.00859.x
   PHILLIPS T, 1994, J AM ACAD DERMATOL, V31, P49, DOI 10.1016/S0190-9622(94)70134-2
   Phillips TJ, 2000, J AM ACAD DERMATOL, V43, P627, DOI 10.1067/mjd.2000.107496
   Pitrou I, 2009, ARCH INTERN MED, V169, P1756, DOI 10.1001/archinternmed.2009.306
   Posnett J, 2009, J Wound Care, V18, P154
   PRENTICE RL, 1989, STAT MED, V8, P431, DOI 10.1002/sim.4780080407
   Price P, 1999, J Wound Care, V8, P306
   Price PE, 2008, DIABETES-METAB RES, V24, pS101, DOI 10.1002/dmrr.851
   Price PE, 2008, INT WOUND J, V5, P159, DOI 10.1111/j.1742-481X.2008.00471.x
   Prompers L, 2008, DIABETOLOGIA, V51, P1826, DOI 10.1007/s00125-008-1089-6
   Prompers L, 2008, DIABETIC MED, V25, P700, DOI 10.1111/j.1464-5491.2008.02445.x
   Prompers L, 2008, DIABETOLOGIA, V51, P747, DOI 10.1007/s00125-008-0940-0
   Prompers L, 2007, DIABETOLOGIA, V50, P18, DOI 10.1007/s00125-006-0491-1
   RagnarsonTennvall G, 1997, PHARMACOECONOMICS, V12, P42, DOI 10.2165/00019053-199712010-00005
   Ravanti L, 2000, INT J MOL MED, V6, P391
   Robson MC, 1999, WOUND REPAIR REGEN, V7, P90, DOI 10.1046/j.1524-475X.1999.00090.x
   Robson MC, 2004, WOUND REPAIR REGEN, V12, P38, DOI 10.1111/j.1067-1927.2004.012109.x
   Ryan Siobhan, 2003, Ostomy Wound Manage, V49, P16
   Sackett DL, 1996, BMJ-BRIT MED J, V312, P71, DOI 10.1136/bmj.312.7023.71
   Schanzer A, 2009, J VASC SURG, V50, P769, DOI 10.1016/j.jvs.2009.05.055
   Schanzer A, 2008, J VASC SURG, V48, P1464, DOI 10.1016/j.jvs.2008.07.062
   Schmutz JL, 2008, INT WOUND J, V5, P172, DOI 10.1111/j.1742-481X.2008.00453.x
   Sheehan P, 2006, PLAST RECONSTR SURG, V117, p239S, DOI 10.1097/01.prs.0000222891.74489.33
   Siebert M, 2002, INT J TECHNOL ASSESS, V18, P733
   Steed David L, 2006, Int Wound J, V3, P40, DOI 10.1111/j.1742-4801.2006.00178.x
   Svensjö T, 2002, TRANSPLANTATION, V73, P1033, DOI 10.1097/00007890-200204150-00004
   Tallman P, 1997, ARCH DERMATOL, V133, P1231, DOI 10.1001/archderm.133.10.1231
   Tarlton JF, 1999, WOUND REPAIR REGEN, V7, P347, DOI 10.1046/j.1524-475X.1999.00347.x
   Vaneau M, 2007, ARCH DERMATOL, V143, P1291, DOI 10.1001/archderm.143.10.1291
   Vowden K, 1995, Br J Nurs, V4, P775
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Walters SJ, 1999, QUAL LIFE RES, V8, P327, DOI 10.1023/A:1008992006845
   Williams C, 2000, Br J Nurs, V9, P237
   Wissing U, 2002, SCAND J CARING SCI, V16, P59, DOI 10.1046/j.1471-6712.2002.00051.x
   Wolcott RD, 2010, J WOUND CARE, V19, P45, DOI 10.12968/jowc.2010.19.2.46966
NR 132
TC 211
Z9 219
U1 0
U2 8
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2062-2916
J9 J WOUND CARE
JI J. Wound Care
PD JUN
PY 2010
VL 19
IS 6
BP 239
EP 268
PG 30
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA V29CL
UT WOS:000208726400004
DA 2026-07-24
ER

PT J
AU Li, X
   Ding, W
   Wang, J
AF Li, Xin
   Ding, Wei
   Wang, Jun
TI Negative pressure sealing drainage with antibiotic bone cement for the
   treatment of skin and soft tissue defects in the older population with
   bone exposure
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE antibiotic; bone cement; bone exposure; drainage; older; soft tissue
   trauma defect; vacuum sealing drainage; wound; wound care; wound
   dressing; wound healing
AB Objective: To observe the clinical efficacy of vacuum sealing drainage (VSD) combined with antibiotic bone cement in the treatment of skin and soft tissue defects of the extremities with bone exposure in the older population.
   Method: From January 2016 to December 2018, VSD combined with antibiotic bone cement was used to treat 12 older patients with skin and soft tissue defects of the extremities and bone exposure. The study cohort consisted of eight male patients and four female patients aged between 60-95 years, with a median of 75 years. The injury sites included four cases of hand, one case of calf, one case of ankle and six cases of back of foot. The area of skin and soft tissue defects ranged from 2.7x4.1cm to 4.8x4.9cm. There were four infected wounds and eight contaminated wounds. The time from injury to operation was 1.5-6 hours, with a median of 5 hours. In the first stage of the treatment, the wound was covered with a VSD dressing; in the second stage the VSD dressing was replaced with antibiotic bone cement after infection control; and in the third stage, the bone cement was removed and the wound was transplanted with medium-thickness skin grafts according to the wound condition. The skin graft survival and wound healing were assessed.
   Results: After the first-stage debridement, three of the 12 patients had wound infections, including two cases of meticillin-resistant Staphylococcus aureus infection and one case of Pseudomonas aeruginosa infection. After the bone cement was removed in the third stage, five of the 12 patients underwent free medium-thickness skin grafting on the wound surface (the area of the autologous skin ranged from 2.9x4.3cm to 4.9x5.0cm), and seven patients continued to change dressing routinely. All patients were followed up for 4-15 months, with a median of 10 months. All skin grafts survived and the wounds healed. The healing time was 48-115 days, with a median of 72 days. At the last follow-up, the skin of the affected limb was slightly darker than the surrounding skin, and the appearance was smooth, without obvious scar tissue formation.
   Conclusion: VSD combined with antibiotic bone cement in the treatment of skin and soft tissue defects of the extremities with bone exposure in the older population has a high survival rate of skin grafts and good wound healing. It is worthy of clinical application.
C1 [Li, Xin; Ding, Wei; Wang, Jun] Wenzhou Med Univ, Peoples Hosp Xiaoshan Dist 1, Xiaoshan Affiliated Hosp, Hangzhou, Zhejiang, Peoples R China.
C3 Wenzhou Medical University
RP Wang, J (通讯作者)，Wenzhou Med Univ, Peoples Hosp Xiaoshan Dist 1, Xiaoshan Affiliated Hosp, Hangzhou, Zhejiang, Peoples R China.
EM 323372702@qq.com
CR Al Thaher Y, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0207753
   [Anonymous], 2020, ZHONGGUO GU SHANG, V33, P873, DOI [10.12200/j, DOI 10.12200/J]
   Chen G, 2018, INT J MOL MED, V42, P3073, DOI 10.3892/ijmm.2018.3915
   Elfeki B, 2019, ANN PLAS SURG, V83, pE50, DOI 10.1097/SAP.0000000000002044
   Khandaker M, 2017, NANOMATERIALS-BASEL, V7, DOI 10.3390/nano7070175
   Klein C, 2020, J TISSUE ENG REGEN M, V14, P1349, DOI 10.1002/term.3097
   Kong XG, 2020, EXP THER MED, V20, P2173, DOI 10.3892/etm.2020.8921
   Liang M, 2022, MILITARY MED RES, V34, P85
   Liu JY, 2017, INT J MOL MED, V39, P879, DOI 10.3892/ijmm.2017.2919
   Lou XH, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001709
   Masquelet A C, 2000, Ann Chir Plast Esthet, V45, P346
   Niu XF, 2017, ORTHOP TRAUMATOL-SUR, V103, P461, DOI 10.1016/j.otsr.2017.01.008
   Qu WQ, 2016, J ORTHOP SURG RES, V11, DOI 10.1186/s13018-016-0471-1
   Shah SR, 2017, TISSUE ENG PT A, V23, P91, DOI [10.1089/ten.tea.2016.0389, 10.1089/ten.TEA.2016.0389]
   Song Yong-Huan, 2016, Zhongguo Gu Shang, V29, P761, DOI 10.3969/j.issn.1003-0034.2016.08.017
   World Health Organization, PREV CARD DIS GUID A
NR 16
TC 3
Z9 4
U1 0
U2 7
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD FEB
PY 2023
VL 32
IS 2
BP 104
EP 108
DI 10.12968/jowc.2023.32.2.104
PG 5
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 8Q4HN
UT WOS:000927170100007
PM 36735529
DA 2026-07-24
ER

PT J
AU Ji, MR
   Yuan, ZX
AF Ji, Minrui
   Yuan, Zaixin
TI The application of traditional Chinese medicine polysaccharides in wound
   healing: A review
SO INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
LA English
DT Review
ID KONJAC GLUCOMANNAN; PROLIFERATION; IMMUNOREGULATION; NANOPARTICLES;
   INFLAMMATION; EXPRESSION; REPAIR; CELLS; L.
AB "Skin wound" refers to damage or disruption of skin tissue caused by trauma, burns, surgeries, or other factors. Currently available treatment systems are relatively limited, and traditional methods such as debridement using basic materials like gauze, bandages, or vacuum sealing drainage are commonly employed. These approaches often overlook individual patient differences, leading to prolonged pain and recurrent infections. Consequently, there is an urgent need for safe and effective new materials to optimize existing treatment systems in order to enhance the management of skin wounds. In recent years, studies have reported the effects of polysaccharides derived from traditional Chinese medicine (TCMPs) including hemostatic, anti-inflammatory, antioxidative, cell migration, angiogenesis enhancement, and collagen deposition stimulation effects. These findings underscore their potential in treating skin wounds. The aim of this review is to investigate the therapeutic effects of TCMPs in skin wound healing. This investigation aims to analyze recent research advancements in this field by classifying and summarizing existing findings based on different mechanisms of action. Furthermore, various drug delivery methods for TCMP will also be reviewed to provide a theoretical foundation for future developments concerning the application of these compounds in skin wound treatment.
C1 [Ji, Minrui] Nantong Univ, Med Sch Nantong Univ, Dept Orthopaed, Affiliated Hosp, Nantong 226001, Peoples R China.
   [Yuan, Zaixin] Nantong Univ, Med Sch Nantong Univ, Dept Resp & Crit Care Med, Affiliated Hosp, Nantong 226001, Peoples R China.
C3 Nantong University; Nantong University
RP Yuan, ZX (通讯作者)，Nantong Univ, Med Sch Nantong Univ, Dept Resp & Crit Care Med, Affiliated Hosp, Nantong 226001, Peoples R China.
EM yuanzaixin1998@163.com
FU Postgraduate Research & Practice Innovation Program of Jiangsu Province
   [SJCX24_2062, AwzPx8774d]
FX This work was supported by Postgraduate Research & Practice Innovation
   Program of Jiangsu Province (SJCX24_2062) . The schematic works of this
   study was supported by Figdraw.com (ID: AwzPx8774d) .
CR Akbal A, 2024, ALGAL RES, V77, DOI 10.1016/j.algal.2023.103356
   Bowler PG, 2001, CLIN MICROBIOL REV, V14, P244, DOI 10.1128/CMR.14.2.244-269.2001
   Broughton George 2nd, 2006, Plast Reconstr Surg, V117, p1e, DOI 10.1097/01.prs.0000222562.60260.f9
   Sanchez MC, 2018, ANTIOXIDANTS-BASEL, V7, DOI 10.3390/antiox7080098
   Cao Y, 2024, J MOL LIQ, V398, DOI 10.1016/j.molliq.2024.124352
   Chen J, 2024, POULTRY SCI, V103, DOI 10.1016/j.psj.2024.103638
   Chen JK, 2019, INT J BIOL MACROMOL, V130, P827, DOI 10.1016/j.ijbiomac.2019.02.137
   Chen MJ, 2024, INT J BIOL MACROMOL, V277, DOI 10.1016/j.ijbiomac.2024.134572
   Chen QQ, 2021, J ETHNOPHARMACOL, V267, DOI 10.1016/j.jep.2020.113542
   Chen SW, 2024, INT J BIOL MACROMOL, V282, DOI 10.1016/j.ijbiomac.2024.136965
   Chen Y, 2023, INT J BIOL MACROMOL, V224, P510, DOI 10.1016/j.ijbiomac.2022.10.140
   Chen Y, 2024, FOODS, V13, DOI 10.3390/foods13233882
   Chen ZL, 2021, CANCER CELL INT, V21, DOI 10.1186/s12935-021-01785-3
   Chen ZY, 2020, CARBOHYD POLYM, V227, DOI 10.1016/j.carbpol.2019.115362
   Cheng ZF, 2024, CHEM ENG J, V492, DOI [10.1016/j.cej.2024.152112, 10.1016/j.cej.2024.152403]
   Colvin KM, 2011, PLOS PATHOG, V7, DOI 10.1371/journal.ppat.1001264
   Daeschlein G, 2013, INT WOUND J, V10, P9, DOI 10.1111/iwj.12175
   Ding L, 2025, INT J BIOL MACROMOL, V288, DOI 10.1016/j.ijbiomac.2024.138575
   Dong JY, 2023, BIOCHEM BIOPH RES CO, V656, P46, DOI 10.1016/j.bbrc.2023.03.027
   Dong L, 2020, BIOMED PHARMACOTHER, V130, DOI 10.1016/j.biopha.2020.110537
   Eming SA, 2007, J INVEST DERMATOL, V127, P514, DOI 10.1038/sj.jid.5700701
   Feng AQ, 2024, INT J BIOL MACROMOL, V266, DOI 10.1016/j.ijbiomac.2024.131171
   Gan ZK, 2024, INT J BIOL MACROMOL, V276, DOI 10.1016/j.ijbiomac.2024.133614
   Gao SY, 2024, INT J BIOL MACROMOL, V281, DOI 10.1016/j.ijbiomac.2024.136472
   Gong HX, 2022, INT J BIOL MACROMOL, V211, P711, DOI 10.1016/j.ijbiomac.2022.05.087
   Guo J, 2018, DRUG DELIV, V25, P1802, DOI 10.1080/10717544.2018.1516006
   Guo YX, 2023, TALANTA, V253, DOI 10.1016/j.talanta.2022.124053
   Han X, 2024, CARBOHYDR POLYM TECH, V7, DOI 10.1016/j.carpta.2024.100492
   He J, 2023, INT J BIOL MACROMOL, V240, DOI 10.1016/j.ijbiomac.2023.124487
   He XM, 2024, INT J BIOL MACROMOL, V261, DOI 10.1016/j.ijbiomac.2024.129874
   He XR, 2020, CARBOHYD POLYM, V229, DOI 10.1016/j.carbpol.2019.115548
   Hu WJ, 2024, INT J BIOL MACROMOL, V282, DOI 10.1016/j.ijbiomac.2024.137089
   Hu YC, 2022, J FUNCT FOODS, V94, DOI 10.1016/j.jff.2022.105097
   Huan CC, 2024, INT J BIOL MACROMOL, V274, DOI 10.1016/j.ijbiomac.2024.133455
   Huang ZF, 2024, INT J BIOL MACROMOL, V271, DOI 10.1016/j.ijbiomac.2024.132584
   Huang ZF, 2023, INT J BIOL MACROMOL, V242, DOI 10.1016/j.ijbiomac.2023.125122
   Jia JH, 2023, BIOMED PHARMACOTHER, V168, DOI 10.1016/j.biopha.2023.115809
   Jiang ZG, 2022, J FUNCT FOODS, V89, DOI 10.1016/j.jff.2021.104916
   Jin ML, 2014, INT J BIOL MACROMOL, V64, P257, DOI 10.1016/j.ijbiomac.2013.12.002
   Krzyszczyk P, 2018, FRONT PHYSIOL, V9, DOI 10.3389/fphys.2018.00419
   Lei J, 2022, INT J BIOL MACROMOL, V222, P3215, DOI 10.1016/j.ijbiomac.2022.10.094
   Li F, 2024, INT J BIOL MACROMOL, V260, DOI 10.1016/j.ijbiomac.2024.129682
   Li QZ, 2024, INT J BIOL MACROMOL, V260, DOI 10.1016/j.ijbiomac.2024.129528
   Li SY, 2024, MATER DESIGN, V241, DOI 10.1016/j.matdes.2024.112967
   Li YG, 2023, INT J BIOL MACROMOL, V244, DOI 10.1016/j.ijbiomac.2023.124999
   Lian YP, 2021, INT J BIOL MACROMOL, V176, P589, DOI 10.1016/j.ijbiomac.2021.02.062
   Liang YY, 2021, BIOMED PHARMACOTHER, V141, DOI 10.1016/j.biopha.2021.111843
   Lin F, 2024, INT J BIOL MACROMOL, V283, DOI 10.1016/j.ijbiomac.2024.137550
   Lindholm C, 2016, INT WOUND J, V13, P5, DOI 10.1111/iwj.12623
   Liu C, 2010, BMC COMPLEM ALTERN M, V10, DOI 10.1186/1472-6882-10-79
   Liu J, 2022, SMALL, V18, DOI 10.1002/smll.202106172
   Liu M, 2022, INT J BIOL MACROMOL, V205, P615, DOI 10.1016/j.ijbiomac.2022.02.089
   Liu Q, 2024, INT J BIOL MACROMOL, V269, DOI 10.1016/j.ijbiomac.2024.131872
   Liu XW, 2024, CARBOHYD POLYM, V345, DOI 10.1016/j.carbpol.2024.122574
   Liu Y, 2024, INT J BIOL MACROMOL, V266, DOI 10.1016/j.ijbiomac.2024.131170
   Liu ZD, 2022, INT J BIOL MACROMOL, V207, P570, DOI 10.1016/j.ijbiomac.2022.03.039
   Lu YB, 2020, BIOMED PHARMACOTHER, V127, DOI 10.1016/j.biopha.2020.110136
   Luo H, 2019, CHIN MED-UK, V14, DOI 10.1186/s13020-019-0270-9
   Luo XG, 2012, J POLYM RES, V19, DOI 10.1007/s10965-012-9849-x
   Lv JY, 2023, MATER DESIGN, V226, DOI 10.1016/j.matdes.2023.111655
   Maalej H, 2023, EUR POLYM J, V183, DOI 10.1016/j.eurpolymj.2022.111763
   Mehwish HM, 2021, INT J BIOL MACROMOL, V184, P144, DOI 10.1016/j.ijbiomac.2021.05.202
   Mittal M, 2014, ANTIOXID REDOX SIGN, V20, P1126, DOI 10.1089/ars.2012.5149
   Moura J, 2019, CLIN IMMUNOL, V200, P43, DOI 10.1016/j.clim.2019.02.002
   Mutailifu P, 2022, PROCESS BIOCHEM, V121, P339, DOI 10.1016/j.procbio.2022.06.026
   Naik E, 2011, J EXP MED, V208, P417, DOI 10.1084/jem.20110367
   Nie SS, 2024, INT J BIOL MACROMOL, V281, DOI 10.1016/j.ijbiomac.2024.136280
   Opneja A, 2019, THROMB RES, V179, P56, DOI 10.1016/j.thromres.2019.05.001
   Park SG, 2005, AM J PATHOL, V166, P387, DOI 10.1016/S0002-9440(10)62262-6
   Qiu MY, 2024, INT J BIOL MACROMOL, V254, DOI 10.1016/j.ijbiomac.2023.128015
   Qu Y, 2016, CARBOHYD POLYM, V148, P345, DOI 10.1016/j.carbpol.2016.04.081
   Rao SY, 2022, J NANOBIOTECHNOL, V20, DOI 10.1186/s12951-022-01490-x
   Saraiva MM, 2023, J BIOMED MATER RES B, V111, P220, DOI 10.1002/jbm.b.35146
   Seweryn E, 2021, NUTRIENTS, V13, DOI 10.3390/nu13082725
   Sha WJ, 2023, PHYTOMEDICINE, V112, DOI 10.1016/j.phymed.2023.154667
   Shi S, 2022, INT J BIOL MACROMOL, V209, P50, DOI 10.1016/j.ijbiomac.2022.03.089
   Song QY, 2022, CARBOHYD RES, V522, DOI 10.1016/j.carres.2022.108698
   Sun QY, 2020, INT J BIOL MACROMOL, V164, P1484, DOI 10.1016/j.ijbiomac.2020.07.208
   Tabandeh MR, 2014, INT J BIOL MACROMOL, V65, P424, DOI 10.1016/j.ijbiomac.2014.01.055
   Takeo M, 2015, CSH PERSPECT MED, V5, DOI 10.1101/cshperspect.a023267
   Tang DX, 2024, INT J BIOL MACROMOL, V266, DOI 10.1016/j.ijbiomac.2024.131106
   Verdolino Davide Vincenzo, 2021, Emerg Top Life Sci, V5, P523, DOI [10.1042/etls20200346, 10.1042/ETLS20200346]
   Wang C, 2021, FRONT IMMUNOL, V12, DOI 10.3389/fimmu.2021.803037
   Wang C, 2020, CARBOHYD POLYM, V229, DOI 10.1016/j.carbpol.2019.115404
   Wang CM, 2006, BIOTECHNOL LETT, V28, P539, DOI 10.1007/s10529-006-0011-x
   Wang J, 2024, CARBOHYD RES, V544, DOI 10.1016/j.carres.2024.109230
   Wang JM, 2016, CARBOHYD POLYM, V140, P6, DOI 10.1016/j.carbpol.2015.12.050
   Wang KP, 2023, INT J BIOL MACROMOL, V253, DOI 10.1016/j.ijbiomac.2023.127126
   Wang R, 2025, INT J BIOL MACROMOL, V293, DOI 10.1016/j.ijbiomac.2024.139316
   Wang SQ, 2024, J ETHNOPHARMACOL, V323, DOI 10.1016/j.jep.2023.117680
   Wang XL, 2022, ARAB J CHEM, V15, DOI 10.1016/j.arabjc.2022.104132
   Wei J, 2023, FOOD BIOSCI, V55, DOI 10.1016/j.fbio.2023.102938
   Wen JP, 2023, INT J BIOL MACROMOL, V248, DOI 10.1016/j.ijbiomac.2023.125557
   Wilkinson HN, 2020, OPEN BIOL, V10, DOI 10.1098/rsob.200223
   Wu Y, 2019, NUCLEIC ACIDS RES, V47, pD1110, DOI 10.1093/nar/gky1021
   Xiang JX, 2022, INT J BIOL MACROMOL, V196, P1, DOI 10.1016/j.ijbiomac.2021.11.166
   Xie HX, 2018, INT J BIOL MACROMOL, V107, P93, DOI 10.1016/j.ijbiomac.2017.08.142
   Xie Y, 2018, INT J BIOL MACROMOL, V112, P1225, DOI 10.1016/j.ijbiomac.2018.02.075
   Xu AA, 2022, INT J BIOL MACROMOL, V214, P402, DOI 10.1016/j.ijbiomac.2022.06.115
   Xu JT, 2024, INT J BIOL MACROMOL, V258, DOI 10.1016/j.ijbiomac.2023.129004
   Xu W, 2014, FOOD CHEM, V158, P171, DOI 10.1016/j.foodchem.2014.02.093
   Xue HK, 2024, INT J BIOL MACROMOL, V262, DOI 10.1016/j.ijbiomac.2024.129923
   Yadu N, 2025, INT J PHARMACEUT, V670, DOI 10.1016/j.ijpharm.2024.125117
   Yan Q, 2022, CARBOHYD POLYM, V293, DOI 10.1016/j.carbpol.2022.119696
   Yan TT, 2024, INT J BIOL MACROMOL, V261, DOI 10.1016/j.ijbiomac.2024.129908
   Yang B, 2020, MAT SCI ENG C-MATER, V110, DOI 10.1016/j.msec.2020.110718
   Yang HR, 2023, FOOD BIOSCI, V51, DOI 10.1016/j.fbio.2022.102310
   Yang L, 2020, MAT SCI ENG C-MATER, V117, DOI 10.1016/j.msec.2020.111265
   Yang X, 2022, INT J BIOL MACROMOL, V215, P550, DOI 10.1016/j.ijbiomac.2022.06.131
   Yang XQ, 2020, INT J BIOL MACROMOL, V143, P314, DOI 10.1016/j.ijbiomac.2019.11.208
   Yang YQ, 2022, INT J BIOL MACROMOL, V210, P518, DOI 10.1016/j.ijbiomac.2022.04.206
   Yang Y, 2015, COLLOID SURFACE B, V136, P111, DOI 10.1016/j.colsurfb.2015.09.006
   Yanuriati A, 2017, CARBOHYD POLYM, V156, P56, DOI 10.1016/j.carbpol.2016.08.080
   Ye D, 2023, INT J BIOL MACROMOL, V252, DOI 10.1016/j.ijbiomac.2023.126484
   Ye GS, 2024, INT J BIOL MACROMOL, V254, DOI 10.1016/j.ijbiomac.2023.127914
   Ye SX, 2022, J SCI FOOD AGR, V102, P4333, DOI 10.1002/jsfa.11786
   Yuan Y, 2022, CHEM ENG J, V433, DOI 10.1016/j.cej.2021.133859
   Yue YM, 2024, PROCESS BIOCHEM, V137, P41, DOI 10.1016/j.procbio.2023.12.009
   Zeng PJ, 2019, PROG MOL BIOL TRANSL, V163, P423, DOI 10.1016/bs.pmbts.2019.03.003
   Zhang CW, 2024, INT J BIOL MACROMOL, V268, DOI 10.1016/j.ijbiomac.2024.131816
   Zhang HY, 2023, INT J BIOL MACROMOL, V253, DOI 10.1016/j.ijbiomac.2023.127189
   Zhang HF, 2018, INT J BIOL MACROMOL, V112, P862, DOI 10.1016/j.ijbiomac.2018.01.214
   Zhang J, 2024, EUR POLYM J, V215, DOI 10.1016/j.eurpolymj.2024.113209
   Zhang Q, 2022, INT J BIOL MACROMOL, V211, P249, DOI 10.1016/j.ijbiomac.2022.05.072
   Zhang SJ, 2022, CARBOHYD POLYM, V295, DOI 10.1016/j.carbpol.2022.119794
   Zhang WW, 2024, CARBOHYD POLYM, V326, DOI 10.1016/j.carbpol.2023.121580
   Zhang XJ, 2024, INT J BIOL MACROMOL, V270, DOI 10.1016/j.ijbiomac.2024.132182
   Zhang XX, 2024, FOOD CHEM X, V22, DOI 10.1016/j.fochx.2024.101271
   Zhang ZJ, 2024, INT J BIOL MACROMOL, V278, DOI 10.1016/j.ijbiomac.2024.134919
   Zhao RL, 2016, INT J MOL SCI, V17, DOI 10.3390/ijms17122085
   Zhao SZ, 2021, FOOD SCI HUM WELL, V10, P508, DOI 10.1016/j.fshw.2021.04.013
   Zhao Y, 2023, FOOD CHEM X, V18, DOI 10.1016/j.fochx.2023.100682
   Zheng QR, 2019, CYTA-J FOOD, V17, P1, DOI 10.1080/19476337.2018.1541195
   Zhong GF, 2023, INT J BIOL MACROMOL, V234, DOI 10.1016/j.ijbiomac.2023.123693
   Zhou LP, 2020, FOOD HYDROCOLLOID, V104, DOI 10.1016/j.foodhyd.2020.105702
   Zhou SY, 2023, J MOL STRUCT, V1273, DOI 10.1016/j.molstruc.2022.134379
   Zhu L, 2021, J DRUG DELIV SCI TEC, V66, DOI 10.1016/j.jddst.2021.102890
   Zhu L, 2021, MAT SCI ENG C-MATER, V129, DOI 10.1016/j.msec.2021.112374
   Zhu M, 2024, CHEM ENG J, V491, DOI 10.1016/j.cej.2024.152131
   Zou YN, 2020, INT J BIOL MACROMOL, V148, P921, DOI 10.1016/j.ijbiomac.2020.01.190
NR 140
TC 10
Z9 10
U1 17
U2 49
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 0141-8130
EI 1879-0003
J9 INT J BIOL MACROMOL
JI Int. J. Biol. Macromol.
PD APR
PY 2025
VL 304
AR 140993
DI 10.1016/j.ijbiomac.2025.140993
EA FEB 2025
PN 2
PG 12
WC Biochemistry & Molecular Biology; Chemistry, Applied; Polymer Science
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biochemistry & Molecular Biology; Chemistry; Polymer Science
GA X7W4I
UT WOS:001427402200001
PM 39952517
DA 2026-07-24
ER

PT J
AU Lin, HS
   Zhang, B
   Wang, YH
   Li, B
   Ren, BX
   Liu, CH
AF Lin, Hai-Shan
   Zhang, Bo
   Wang, Yao-Hua
   Li, Bo
   Ren, Bo-Xuan
   Liu, Chang-Hao
TI Limb Salvage in Infected Tibial Nonunion with Bone Loss: A Case Report
   of a Modified Masquelet-Ilizarov Technique
SO ACTA ORTHOPAEDICA BELGICA
LA English
DT Article
DE Masquelet Technique; Ilizarov External Fixator; Bone Transport; Bone
   Infection; Bone Defect; Open fractures
ID TRANSPORT; FRACTURES; MANAGEMENT; AMPUTATION; DEFECTS
AB Gustilo-Anderson type III fractures, characterized by extensive soft-tissue damage, require urgent debridement and external fixation to minimize infection risk. Despite these measures, deep infections and osteomyelitis may still develop, sometimes leading to amputation. The Masquelet and Ilizarov techniques have emerged as effective approaches for reconstructing infected bone defects by promoting bone regeneration and soft-tissue healing. A 57-year-old male sustained a Gustilo-Anderson type IIIB open tibial-fibular fracture with severe soft-tissue injury in a traffic accident. Initial treatment included emergency debridement, external fixation, and vacuum sealing drainage (VSD). However, he developed a progressive infection with extensive soft-tissue necrosis and osteomyelitis. A modified Masquelet-Ilizarov technique was employed, involving necrotic bone resection, antibiotic cement spacer implantation, and subsequent bone transport using an Ilizarov frame. At final follow-up, satisfactory bone union and functional limb recovery were achieved.The combined Masquelet-Ilizarov technique offers a viable limb-salvage strategy for infected Gustilo-Anderson type IIIB tibial fractures with bone loss, yielding acceptable clinical and functional outcomes.
C1 [Lin, Hai-Shan; Zhang, Bo; Wang, Yao-Hua; Li, Bo; Ren, Bo-Xuan; Liu, Chang-Hao] Hexi Univ, Affiliated Zhangye Peoples Hosp, Zhangye 734000, Gansu, Peoples R China.
   [Wang, Yao-Hua] Hexi Univ, Affiliated Zhangye Peoples Hosp, Dept Orthoped, 67 Xihuan Rd, Zhangye 734000, Gansu, Peoples R China.
C3 Hexi University; Hexi University
RP Wang, YH (通讯作者)，Hexi Univ, Affiliated Zhangye Peoples Hosp, Dept Orthoped, 67 Xihuan Rd, Zhangye 734000, Gansu, Peoples R China.
EM 1269182095@qq.com
RI ; Lin, Haishan/ACP-2775-2022
OI Lin, Haishan/0000-0001-5356-4211; 
FU President's Fund of Hexi University [2025YB043]
FX Supported by: President's Fund of Hexi University (2025YB043) .
CR Borzunov DY, 2022, WORLD J ORTHOP, V13, P278, DOI 10.5312/wjo.v13.i3.278
   Chen SH, 2024, ORTHOP SURG, V16, P94, DOI 10.1111/os.13940
   Dauwe J, 2024, ACTA ORTHOP BELG, V90, DOI 10.52628/90.2.10777
   El-Hadidi TT, 2018, ACTA ORTHOP BELG, V84, P384
   Fochtmann A, 2014, J TRAUMA ACUTE CARE, V76, P1076, DOI 10.1097/TA.0000000000000154
   Iacobellis C, 2010, STRATEG TRAUMA LIMB, V5, P17, DOI 10.1007/s11751-010-0085-9
   Laursen M B, 2000, Acta Orthop Belg, V66, P279
   Li ZH, 2023, ORTHOP SURG, V15, P3046, DOI 10.1111/os.13936
   Makhdoom A, 2019, CUREUS J MED SCIENCE, V11, DOI 10.7759/cureus.4973
   Mathieu L, 2020, ACTA ORTHOP BELG, V86, P606
   Mekki WA, 2022, ACTA ORTHOP BELG, V88, P127, DOI 10.52628/88.1.16
   Ndlovu S, 2023, BONE JOINT J, V105B, P21, DOI 10.1302/0301-620X.105B1.BJJ-2022-0934.R1
   PALEY D, 1989, CLIN ORTHOP RELAT R, P146
   Rupp M, 2020, INJURY, V51, pS57, DOI 10.1016/j.injury.2019.10.074
   Sagi HC, 2021, J ORTHOP TRAUMA, V35, P449, DOI 10.1097/BOT.0000000000002094
   Schlatterer DR, 2015, CLIN ORTHOP RELAT R, V473, P1802, DOI 10.1007/s11999-015-4140-1
   Suzuki T, 2023, SCI REP-UK, V13, DOI 10.1038/s41598-023-34142-7
   Wei BX, 2025, FRONT PUBLIC HEALTH, V13, DOI 10.3389/fpubh.2025.1583523
   Xuming W, 2024, ACTA ORTHOP BELG, V90, P513, DOI 10.52628/90.3.12619
   Yang RH, 2016, MED SCI MONITOR, V22, DOI 10.12659/MSM.896009
   Yin P, 2014, ACTA ORTHOP BELG, V80, P426
   Youbong TJ, 2021, ANTIBIOTICS-BASEL, V10, DOI 10.3390/antibiotics10121513
   Yusuf E, 2015, ACTA ORTHOP BELG, V81, P327
NR 23
TC 0
Z9 0
U1 0
U2 0
PU ACTA MEDICA BELGICA
PI BRUSSELS
PA AVENUE WINSTON CHURCHILL, WINSTON CHURCHILL-LAAN, 11 BOX 30, B-1180
   BRUSSELS, BELGIUM
SN 0001-6462
J9 ACTA ORTHOP BELG
JI Acta Orthop. Belg.
PD MAR
PY 2026
VL 92
AR 15229
DI 10.52628/92.1.15229
PG 10
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA HK7CV
UT WOS:001756351500001
PM 42012051
DA 2026-07-24
ER

PT J
AU Zhang, JY
   Zhao, BK
   Wei, WH
   Wang, D
   Wang, HY
   Zhang, AJ
   Tao, CB
   Li, XY
   Li, Q
   Jin, PS
AF Zhang, Jingyu
   Zhao, Bingkun
   Wei, Wuhan
   Wang, Dan
   Wang, Haoyu
   Zhang, Aijun
   Tao, Changbo
   Li, Xueyang
   Li, Qiang
   Jin, Peisheng
TI Prospective, Randomized, and Controlled Study of a Human Umbilical Cord
   Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
SO JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
LA English
DT Article
ID ULCERATION; TRANSPLANTATION; DIAGNOSIS; SAFETY
AB With the development of society and the economy, the incidence of diabetic foot ulcers continues to increase. Currently, conventional debridement with dressing changes, hyperbaric oxygen, and vacuum sealing drainage are the main conservative treatments in clinical practice, and large wounds often require skin grafts or skin flap grafts. However, the treatment effects are not ideal, and many complications exist. Due to its complex pathogenesis, long treatment time, significant associated difficulties, and high disability rate, diabetic foot ulcers cause a heavy burden to patients, society, and medical care. According to our previous study, the pharmacological effects of human umbilical cord blood stem cells include nonspecific immune regulation; increased secretion of growth factors, vasoactive factors, and anti-inflammatory factors; enhanced anti-infectious ability of the human body; elimination of inflammation; and promotion of angiogenesis and ulcer healing. These effects suggest stem cells may be useful as an autologous or allogeneic treatment for refractory wounds. Therefore, we are conducting a clinical trial to treat refractory diabetic wounds with human umbilical cord stem cells in our clinic for diabetic foot ulcer patients who meet the inclusion criteria.
C1 [Zhang, Jingyu; Zhao, Bingkun; Wei, Wuhan; Wang, Haoyu; Zhang, Aijun; Tao, Changbo; Li, Xueyang; Li, Qiang; Jin, Peisheng] Xuzhou Med Univ, Affiliated Hosp, Dept Plast Surg, Xuzhou, Peoples R China.
   [Zhang, Jingyu; Wei, Wuhan; Wang, Haoyu] Xuzhou Med Univ, Grad Sch, Xuzhou, Peoples R China.
   [Wang, Dan] Chinese Univ Hong Kong, Inst Tissue Engn & Regenerat Med, Hong Kong, Peoples R China.
   [Wang, Dan] Chinese Univ Hong Kong, Sch Biomed Sci, Hong Kong, Peoples R China.
   [Wang, Dan] Hong Kong Sci Pk, Ctr Neuromusculoskeletal Restorat Med, Hong Kong, Peoples R China.
C3 Xuzhou Medical University; Xuzhou Medical University; Chinese University
   of Hong Kong; Chinese University of Hong Kong
RP Li, Q; Jin, PS (通讯作者)，Xuzhou Med Univ, Affiliated Hosp, Dept Plast Surg, Xuzhou, Peoples R China.
EM LiQ@xzhmu.edu.cn; peishengjin@xzhmu.edu.cn
RI ; Wang, Dan/R-5941-2018; li, qiang/JTV-1165-2023; wei,
   wuhan/NDT-3612-2025
OI Jin, Peisheng/0009-0005-8618-3999; Wang, Dan/0000-0002-5934-9085; 
FU National Natural Science Foundation of China [82172224]; Postgraduate
   Research & Practice Innovation Program of Jiangsu Province
   [SJCX22-1271]; Innovation & Technology Commission (Health@InnoHK)
FX The authors thank the Affiliated Hospital of Xuzhou Medical University
   for its cooperation, including the recruitment and follow-up of patients
   with diabetic foot wounds. The authors also thank the patients who
   participated in the patient needs survey during the design of this
   study.The author (s) announce the receipt of the following financial
   support for research, authorship, and/or publication of this article:
   National Natural Science Foundation of China 82172224, Postgraduate
   Research & Practice Innovation Program of Jiangsu Province
   (SJCX22-1271), and the Innovation & Technology Commission
   (Health@InnoHK).
CR Alberti KGMM, 1998, DIABETIC MED, V15, P539, DOI 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S
   Bacakova L, 2018, BIOTECHNOL ADV, V36, P1111, DOI 10.1016/j.biotechadv.2018.03.011
   Behr B, 2010, PLAST RECONSTR SURG, V126, P1163, DOI 10.1097/PRS.0b013e3181ea42bb
   Boulton AJM, 2013, MED CLIN N AM, V97, P775, DOI 10.1016/j.mcna.2013.03.007
   Burgess JL, 2021, MEDICINA-LITHUANIA, V57, DOI 10.3390/medicina57101072
   Cai JQ, 2016, DIABETES CARE, V39, P149, DOI 10.2337/dc15-0171
   Dulchavsky D, 2008, J INVEST SURG, V21, P270, DOI 10.1080/08941930802216831
   GRIFFIN JW, 1993, PHYS THER, V73, P117, DOI 10.1093/ptj/73.2.117
   Hu YQ, 2021, J NANOBIOTECHNOL, V19, DOI 10.1186/s12951-021-00894-5
   Huang YY, 2021, JAMA NETW OPEN, V4, DOI 10.1001/jamanetworkopen.2021.22607
   KUMAR S, 1994, DIABETIC MED, V11, P480, DOI 10.1111/j.1464-5491.1994.tb00310.x
   Li KL, 2022, J NANOBIOTECHNOL, V20, DOI 10.1186/s12951-021-01236-1
   Lijmer JG, 1996, ULTRASOUND MED BIOL, V22, P391, DOI 10.1016/0301-5629(96)00036-1
   Lipsky BA, 2006, PLAST RECONSTR SURG, V117, p212S, DOI 10.1097/01.prs.0000222737.09322.77
   Margolis DJ, 2013, MED CLIN N AM, V97, P791, DOI 10.1016/j.mcna.2013.03.008
   Meng F., 2022, J Investig Dermatol, V142, P4
   Moon KC, 2019, DIABETES, V68, P837, DOI 10.2337/db18-0699
   Qin HL, 2016, EXP CLIN ENDOCR DIAB, V124, P497, DOI 10.1055/s-0042-103684
   Shen CQ, 2022, BIOENGINEERED, V13, P27, DOI 10.1080/21655979.2021.1997077
   Sun H, 2022, DIABETES RES CLIN PR, V183, DOI 10.1016/j.diabres.2021.109119
   Um S, 2020, WORLD J STEM CELLS, V12, P1511, DOI 10.4252/wjsc.v12.i12.1511
   Virador GM, 2019, METHODS MOL BIOL, V1879, P221, DOI 10.1007/7651_2018_161
   Volmer-Thole M, 2016, INT J MOL SCI, V17, DOI 10.3390/ijms17060917
   Wagner F W Jr, 1981, Foot Ankle, V2, P64
   Wu MA, 2022, STEM CELL RES THER, V13, DOI 10.1186/s13287-022-02770-x
   Xiao MH, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-21387-x
   Yarahmadi A, 2021, EXPERT OPIN BIOL TH, V21, P687, DOI 10.1080/14712598.2021.1897100
   Zhang Z, 2013, AIDS, V27, P1283, DOI 10.1097/QAD.0b013e32835fab77
NR 28
TC 11
Z9 13
U1 2
U2 23
PU JOURNAL OF VISUALIZED EXPERIMENTS
PI CAMBRIDGE
PA 1 ALEWIFE CENTER, STE 200, CAMBRIDGE, MA 02140 USA
SN 1940-087X
J9 JOVE-J VIS EXP
JI J. Vis. Exp.
PD MAR
PY 2023
IS 193
AR e65045
DI 10.3791/65045
PG 12
WC Multidisciplinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Science & Technology - Other Topics
GA A7RK9
UT WOS:000957053000034
PM 36939252
DA 2026-07-24
ER

PT J
AU Sun, XC
   Xu, CX
   Lian, J
   Song, M
AF Sun, Xiaochen
   Xu, Chengxin
   Lian, Juan
   Song, Mei
TI 被撤回的出版物: Analysis of DAT Combined with the VSD Technique in Wound Repair
   of Rats and Its Effect on Inflammatory Factors (Retracted Article)
SO CONTRAST MEDIA & MOLECULAR IMAGING
LA English
DT Article; Retracted Publication
ID ADIPOSE-TISSUE
AB The clinical efficacy of decellularized adipose tissue (DAT) combined with vacuum sealing drainage (VSD) in the treatment of wound healing in rats is investigated, and the changes of inflammatory factors are analyzed. The tissue defect model of SD (Sprague-Dawley) rats is established and divided into the combined group (n = 12) and the control group (n = 12) according to different treatment methods. The control group is treated with a single VSD technique, and the combined group is treated with DAT on the basis of the control group. The wound healing time of the two groups is observed. Wound tissue is collected 1 day, 10 days, 20 days, and 30 days after treatment, and neutrophil infiltration is observed by HE (hematoxylin-eosin) staining. The expression changes of IL-6 and IL-13 at each time point before and after treatment are compared. Histological observation shows that the cell infiltration is reduced in both groups, and the wound repair in the combined group is better than that in the control group. The experimental results show that the DAT combined with the VSD technique can further speed up wound healing and reduce inflammation in rats.
C1 [Sun, Xiaochen; Xu, Chengxin; Lian, Juan; Song, Mei] 940th Hosp Joint Logist Support Force Chinese PLA, Dept Burns & Plast Surg, Lanzhou 730050, Peoples R China.
RP Song, M (通讯作者)，940th Hosp Joint Logist Support Force Chinese PLA, Dept Burns & Plast Surg, Lanzhou 730050, Peoples R China.
EM 15002654008@163.com; xuchengxinxiangce@163.com; lianjuan0430@163.com;
   3180400103@caa.edu.cn
CR Chun SY, 2019, TISSUE ENG REGEN MED, V16, P385, DOI 10.1007/s13770-019-00199-7
   Han T., 2021, FRONT BIOENG BIOTECH, V18, P1
   Huang QQ, 2021, TRANSL PEDIATR, V10, P2489, DOI 10.21037/tp-21-399
   Jiang DS, 2021, INT J MOL SCI, V22, DOI 10.3390/ijms22169006
   Jiang X, 2021, BIOCHEM BIOPH RES CO, V541, P63, DOI 10.1016/j.bbrc.2020.12.108
   Ladhani HA, 2021, AM SURGEON, V87, P1118, DOI 10.1177/0003134820952387
   Leclerc CJ, 2021, BIOMATERIALS, V274, DOI 10.1016/j.biomaterials.2021.120867
   Mohiuddin OA, 2020, ADV EXP MED BIOL, V1212, P57, DOI 10.1007/5584_2019_371
   Monavarian M, 2019, TISSUE ENG PART B-RE, V25, P294, DOI [10.1089/ten.teb.2018.0350, 10.1089/ten.TEB.2018.0350]
   Ren LQ, 2021, INT WOUND J, V18, P787, DOI 10.1111/iwj.13582
   Robb KP, 2021, TISSUE ENG PT A, V27, P618, DOI [10.1089/ten.tea.2020.0180, 10.1089/ten.TEA.2020.0180]
   Shettigar K, 2020, EUR J CLIN MICROBIOL, V39, P2235, DOI 10.1007/s10096-020-03984-8
   Veith AP, 2019, ADV DRUG DELIVER REV, V146, P97, DOI 10.1016/j.addr.2018.09.010
   Wilkinson HN, 2020, OPEN BIOL, V10, DOI 10.1098/rsob.200223
   Xia ZN, 2020, TISSUE ENG REGEN MED, V17, P863, DOI 10.1007/s13770-020-00286-0
   Xue X, 2021, INT WOUND J, V18, P639, DOI 10.1111/iwj.13565
   Yang JZ, 2020, WORLD J STEM CELLS, V12, P585, DOI 10.4252/wjsc.v12.i7.585
NR 17
TC 1
Z9 1
U1 0
U2 0
PU WILEY-HINDAWI
PI LONDON
PA ADAM HOUSE, 3RD FL, 1 FITZROY SQ, LONDON, WIT 5HE, ENGLAND
SN 1555-4309
EI 1555-4317
J9 CONTRAST MEDIA MOL I
JI Contrast Media Mol. Imaging
PD AUG 20
PY 2022
VL 2022
AR 2662876
DI 10.1155/2022/2662876
PG 7
WC Radiology, Nuclear Medicine & Medical Imaging
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Radiology, Nuclear Medicine & Medical Imaging
GA 6P5JD
UT WOS:000890965000001
PM 36072624
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Wei, ZY
   Wang, Q
   Wang, YF
   Fang, XJ
   Zhu, YX
   Cheng, JT
AF Wei, Zhiyi
   Wang, Qian
   Wang, Yanfeng
   Fang, Xiangjian
   Zhu, Yixin
   Cheng, Juntao
TI Necrotizing Fasciitis Shock Syndrome by Group A Hemolytic Streptococcus:
   Report of 6 Cases and Clinical Management
SO CLINICAL LABORATORY
LA English
DT Article
DE type II necrotizing fasciitis streptococcal toxic shock syndrome (STSS);
   group A hemolytic streptococcus (GAS); vacuum sealing drainage (VSD)
AB Background: To explore the comprehensive treatment of group A streptococcus haemolyticus complicated with streptococcal toxic shock syndrome (STSS) in surgery.
   Methods: Six patients with Type II necrotizing fasciitis complicated with STSS were enrolled from September 2018 to October 2019 in the Burn Department at Quanzhou First Hospital. The patients were treated with early incision and reduction of tension, anti-shock, anti-infection, primary debridement and vacuum suction, maintenance of organ function, and adjustment of internal environment, secondary autologous skin graft, and early rehabilitation.
   Results: Five patients were healed, while one elderly patient refused treatment.
   Conclusions: We should be alert to necrotizing fasciitis caused by group A hemolytic streptococcus (GAS) infection and effectively avoid the occurrence of STSS. By making an incision to reduce tension, adopting the principle of anti-infection, and actively anti-shock, maintaining the function of internal organs and the stability of internal environment, debridement and vacuum suction in early and effective stage, followed by self-skin graft to seal the wound and early rehabilitation the treatment of Type II NF and STSS can be effectively improved.
C1 [Wei, Zhiyi; Fang, Xiangjian; Zhu, Yixin; Cheng, Juntao] Quanzhou First Hosp, Dept Burn Intens Care Unit, 250 Dongjie Rd, Quanzhou 362000, Fujian, Peoples R China.
   [Wang, Qian] Quanzhou Coll Vocat Sch & Stomatol, Quanzhou, Fujian, Peoples R China.
   [Wang, Yanfeng] Xiamen Univ, Affiliated Hosp 1, Sch Med, Dept Clin Lab, Xiamen, Fujian, Peoples R China.
C3 Xiamen University
RP Cheng, JT (通讯作者)，Quanzhou First Hosp, Dept Burn Intens Care Unit, 250 Dongjie Rd, Quanzhou 362000, Fujian, Peoples R China.
EM c5481@sina.com
RI Wang, YanFeng/IAO-6494-2023
CR Bi Fan, 2018, Zhongguo Yi Liao Qi Xie Za Zhi, V42, P46, DOI 10.3969/j.issn.1671-7104.2018.01.012
   Bonne SL, 2017, INFECT DIS CLIN N AM, V31, P497, DOI 10.1016/j.idc.2017.05.011
   Chuang KL, 2018, ANN PLAS SURG, V80, pS75, DOI 10.1097/SAP.0000000000001298
   Ikebe T, 2015, EPIDEMIOL INFECT, V143, P864, DOI 10.1017/S0950268814001265
   Kawecki Marek, 2015, Pol Przegl Chir, V87, P1, DOI [10.1515/pjs-2015-0010, 10.1515/pjs-2015-0010]
   Li Longzhu, 2015, Zhonghua Shao Shang Za Zhi, V31, P98
   Liu Mengyao, 2018, Jpn J Med (Lond), V1, P269, DOI [10.31488/jjm.1000127, 10.31488/jjm.1000127]
   Nehme A, 2018, CASE REP INFECT DIS, V2018, DOI 10.1155/2018/4176320
   Nelson GE, 2016, CLIN INFECT DIS, V63, P478, DOI 10.1093/cid/ciw248
   Norkiene I, 2017, ANZ J SURG, V87, P1062, DOI 10.1111/ans.14228
   Stevens DL, 2017, NEW ENGL J MED, V377, P2253, DOI 10.1056/NEJMra1600673
   Tsang KWK, 2016, SEMIN MUSCULOSKEL R, V20, P175, DOI 10.1055/s-0036-1581116
   Vilallonga R, 2019, J SURG CASE REP, DOI 10.1093/jscr/rjz269
NR 13
TC 2
Z9 2
U1 0
U2 6
PU CLIN LAB PUBL
PI HEIDELBERG
PA IM BREITSPIEL 15, HEIDELBERG, D-69126, GERMANY
SN 1433-6510
J9 CLIN LAB
JI Clin. Lab.
PY 2021
VL 67
IS 3
BP 851
EP 856
DI 10.7754/Clin.Lab.2020.200801
PG 6
WC Medical Laboratory Technology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Medical Laboratory Technology
GA RZ6XJ
UT WOS:000648745300026
PM 33739051
DA 2026-07-24
ER

PT J
AU Meng, Z
   Wang, YC
   Chao, J
   Ji, YJ
   Sun, YF
   Zhu, J
   Gao, TB
   Chen, S
   Wang, SY
AF Meng, Zhe
   Wang, Yanchen
   Chao, Jun
   Ji, Yongjian
   Sun, Yaofei
   Zhu, Jiang
   Gao, Tongbin
   Chen, Si
   Wang, Shenyang
TI Extensive necrotizing fasciitis of scrotum and abdominal wall: Report of
   two cases and a review of the literature
SO FRONTIERS IN SURGERY
LA English
DT Review
DE necrotizing fasciitis; debridement; antibiotic; vacuum sealing
   draina(VSD)
ID PRESSURE WOUND THERAPY; DETERMINANTS; DIAGNOSIS
AB The incidence rate of necrotizing fasciitis(NF) is low, but it has a high mortality rate. At present, it lacks experience in clinical treatment in municipal and county-level hospitals, insufficient awareness of disease risk, lack of experience in disease surgical intervention, and lack of a set of mature treatment norms and standards. Most patients have no time to transfer to a higher hospital for treatment. In January and April 2022, two cases of large-scale necrotizing fasciitis of the scrotum and abdominal wall were treated in the Department of Urology of Weifang people's Hospital respectively and were clinically cured after active surgical debridement combined with broad-spectrum antibiotics. Through the retrospective analysis of the diagnosis and treatment of two cases of necrotizing fasciitis, this paper analyzes and summarizes the scope of surgical debridement of NF, postoperative dressing changing skills, timing of multiple debridements, application and timing of vacuum sealing drainage(VSD), and the combined use of antibiotics. To provide experience for clinical diagnosis and treatment of necrotizing fasciitis.
C1 [Meng, Zhe; Wang, Yanchen; Chao, Jun; Ji, Yongjian; Sun, Yaofei; Zhu, Jiang; Gao, Tongbin; Chen, Si; Wang, Shenyang] Weifang Med Coll, Yuhe Campus, Weifang, Peoples R China.
   [Meng, Zhe; Wang, Yanchen; Chao, Jun; Ji, Yongjian; Sun, Yaofei; Zhu, Jiang; Gao, Tongbin; Chen, Si; Wang, Shenyang] Weifang peoples Hosp, Dept Urol, Weifang, Peoples R China.
C3 Shandong Second Medical University; Shandong Second Medical University
RP Wang, SY (通讯作者)，Weifang Med Coll, Yuhe Campus, Weifang, Peoples R China.; Wang, SY (通讯作者)，Weifang peoples Hosp, Dept Urol, Weifang, Peoples R China.
EM 2009040210@st.btbu.edu.cn
RI chao, jun/GWU-8430-2022; meng, zhe/GWQ-8413-2022
CR Agel J, 2014, J ORTHOP TRAUMA, V28, P300, DOI 10.1097/BOT.0b013e3182a70f39
   Chen JL, 2001, CLIN INFECT DIS, V33, P6, DOI 10.1086/320874
   Duan HJ, 2020, J WOUND CARE, V29, P510, DOI 10.12968/jowc.2020.29.9.510
   Edlich RF, 2010, J EMERG MED, V39, P261, DOI 10.1016/j.jemermed.2008.06.024
   El-Sabbagh AH, 2017, CHIN J TRAUMATOL, V20, P103, DOI 10.1016/j.cjtee.2016.09.004
   Goh T, 2014, BJS-BRIT J SURG, V101, pE119, DOI 10.1002/bjs.9371
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Johnson LJ, 2021, DIABETES RES CLIN PR, V171, DOI 10.1016/j.diabres.2020.108520
   Kapp DL, 2018, INT J LOW EXTR WOUND, V17, P295, DOI 10.1177/1534734618804037
   Khalid M, 2020, INT J SURG CASE REP, V76, P199, DOI 10.1016/j.ijscr.2020.09.132
   Lancerotto L, 2012, J TRAUMA ACUTE CARE, V72, P560, DOI 10.1097/TA.0b013e318232a6b3
   Li Longzhu, 2015, Zhonghua Shao Shang Za Zhi, V31, P98
   Liu Yuag-Meng, 2005, Journal of Microbiology Immunology and Infection, V38, P430
   Longfei M., 2021, CLIN RES PRACT, V6, P20, DOI [10.19347/j.cnki.2096-1413.202135006, DOI 10.19347/J.CNKI.2096-1413.202135006]
   MCHENRY CR, 1995, ANN SURG, V221, P558, DOI 10.1097/00000658-199505000-00013
   Meekul J, 2017, INT J LOW EXTR WOUND, V16, P108, DOI 10.1177/1534734617701051
   Rogers PJ, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.11880
   Ryssel H, 2010, ARCH ORTHOP TRAUM SU, V130, P1515, DOI 10.1007/s00402-010-1101-8
   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
   Skrede S, 2020, ADV EXP MED BIOL, V1294, P53, DOI 10.1007/978-3-030-57616-5_5
   Wang YS, 2007, INT J DERMATOL, V46, P1036, DOI 10.1111/j.1365-4632.2007.03201.x
   Wong CH, 2003, J BONE JOINT SURG AM, V85A, P1454, DOI 10.2106/00004623-200308000-00005
   Wong Chin-Ho, 2008, Am J Surg, V196, pe19, DOI 10.1016/j.amjsurg.2007.08.076
   Xue X, 2021, INT WOUND J, V18, P639, DOI 10.1111/iwj.13565
   Yadav S, 2017, PAN AFR MED J, V28, DOI 10.11604/pamj.2017.28.246.9606
NR 25
TC 3
Z9 5
U1 0
U2 5
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-875X
J9 FRONT SURG
JI Front. Surg.
PD JUL 19
PY 2022
VL 9
AR 952042
DI 10.3389/fsurg.2022.952042
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 3O6KW
UT WOS:000836945000001
PM 35928030
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Pachuau, L
   Wu, XY
   Fu, ML
   Cui, XM
   Chen, XD
AF Pachuau, Lalrintluangi
   Wu, Xiao-Yan
   Fu, Mu-Lan
   Cui, Xiao-Mei
   Chen, Xiao-Dong
TI Surgical Treatment for Chest "Lock" Keloid Using Autologous
   Split-Thickness Skin Grafting and Postoperative Radiotherapy
SO DERMATOLOGIC SURGERY
LA English
DT Article
ID EXCISION; RECONSTRUCTION; DEFECTS; THERAPY; PART
AB BACKGROUND The treatment of chest "lock" keloids is challenging due to skin defects and a high recurrence rate.
   OBJECTIVE Evaluation of the effectiveness of autologous split-thickness skin graft with local radiotherapy for treating chest "lock" keloids.
   METHODS AND MATERIALS Fifty-seven patients with chest "lock" keloids were treated from July 2018 to September 2020. The skin defects were closed with an autologous split-thickness skin graft (STSG) and vacuum sealing drainage. The donor and the recipient sites received the first session of radiotherapy 72 hours postoperation for 3 consecutive days. Patients underwent follow-up examinations 12 months after surgery. The Patient and Observer Scar Assessment Scale (POSAS) was used to assess the treatment outcome.
   RESULTS Except for the complaints of pain, which did not improve in the patients' assessments (p = .368), POSAS improved significantly after treatment (p < .0001). The cure rate (including cured and partially cured scars) was 100%. No keloid recurrence was observed during the follow-up period.
   CONCLUSION The procedure of treating chest "lock" keloid by keloid debulking and autologous STSG followed by postoperational radiotherapy is a novel combined methodology for treating keloids.
C1 [Pachuau, Lalrintluangi; Wu, Xiao-Yan; Fu, Mu-Lan; Cui, Xiao-Mei; Chen, Xiao-Dong] Nantong Univ, Dept Dermatol, Affiliated Hosp, Nantong, Jiangsu, Peoples R China.
   [Chen, Xiao-Dong] Nantong Univ, Dept Dermatol, Affiliated Hosp, 20 Xisi St, Nantong 226001, Jiangsu, Peoples R China.
C3 Nantong University; Nantong University
RP Chen, XD (通讯作者)，Nantong Univ, Dept Dermatol, Affiliated Hosp, 20 Xisi St, Nantong 226001, Jiangsu, Peoples R China.
EM matetelalrintluangi@yahoo.com; wuxiaoyannt@126.com; 709704310@qq.com;
   cxiaomei88@126.com; dermatochen@ntu.edu.cn
CR Ali A, 2021, Mymensingh Med J, V30, P816
   Andrews JP, 2016, MATRIX BIOL, V51, P37, DOI 10.1016/j.matbio.2016.01.013
   Azzam EZ, 2018, J COSMET DERMATOL-US, V17, P502, DOI 10.1111/jocd.12552
   Bayat A, 2005, BRIT J PLAST SURG, V58, P28, DOI 10.1016/j.bjps.2004.04.024
   Brobst B., 2022, STATPEARLS
   Gold MH, 2014, DERMATOL SURG, V40, P825, DOI 10.1111/dsu.0000000000000050
   Hsieh CL, 2021, DERMATOL SURG, V47, P1438, DOI 10.1097/DSS.0000000000003165
   Jiao H, 2017, FRONT PHYSIOL, V8, DOI 10.3389/fphys.2017.00885
   Keeling BH, 2015, DERMATOL SURG, V41, P989, DOI 10.1097/DSS.0000000000000417
   Kim DY, 2004, PLAST RECONSTR SURG, V113, P1668, DOI 10.1097/01.PRS.0000117199.47891.4F
   Lee YI, 2019, DERMATOL SURG, V45, P802, DOI 10.1097/DSS.0000000000001695
   Li WB, 2014, DERMATOL SURG, V40, P52, DOI 10.1111/dsu.12374
   Liu H, 2021, BMC SURG, V21, DOI 10.1186/s12893-021-01116-3
   Liu S, 2018, AESTHET PLAST SURG, V42, P304, DOI 10.1007/s00266-017-0949-1
   Long X, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004684
   Nguyen KT, 2016, PLAST RECONSTR SURG, V138, P235, DOI 10.1097/PRS.0000000000002242
   Ogawa R, 2017, INT J MOL SCI, V18, DOI 10.3390/ijms18030606
   Ogawa R, 2015, PLAST RECONSTR SURG, V135, P868, DOI 10.1097/PRS.0000000000000962
   Park TH, 2015, J CRANIOFAC SURG, V26, pE571, DOI [10.1097/SCS.0000000000002125, 10.1097/SCS.0000000000001747]
   Shi C, 2018, DERM-ENDOCRINOL, V9, DOI 10.1080/19381980.2018.1448327
   Song KX, 2018, J COSMET DERMATOL-US, V17, P1205, DOI 10.1111/jocd.12782
   Xu XY, 2013, INT UROL NEPHROL, V45, P413, DOI 10.1007/s11255-013-0396-0
   Xue ML, 2022, ADV WOUND CARE, V11, P87, DOI 10.1089/wound.2020.1287
   Yi JW, 2015, PLAST RECONSTR SURG, V135, p609E, DOI 10.1097/PRS.0000000000001204
   Yin YC, 2018, INT J SURG, V50, P43, DOI 10.1016/j.ijsu.2017.12.020
   Zeng A, 2017, ANN PLAS SURG, V79, P280, DOI 10.1097/SAP.0000000000000975
   Zhao Yan-yong, 2003, Zhonghua Zheng Xing Wai Ke Za Zhi, V19, P340
NR 27
TC 6
Z9 6
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1076-0512
EI 1524-4725
J9 DERMATOL SURG
JI Dermatol. Surg.
PD MAY
PY 2023
VL 49
IS 5S
SU 5
BP S64
EP S69
DI 10.1097/DSS.0000000000003777
PG 6
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA F2AK3
UT WOS:000980422400009
PM 37116003
DA 2026-07-24
ER

PT J
AU Li, M
   Wu, F
   Du, J
   Ding, Y
   Zhang, B
   Ding, K
AF Li, Meng
   Wu, Fan
   Du, Jun
   Ding, Yang
   Zhang, Bei
   Ding, Kang
TI Combination Therapy of Vacuum Sealing Drainage and Counter-Current
   Irrigation for Refractory Perianal Wounds
SO JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
LA English
DT Article
ID DRESSINGS
AB Perianal refractory wounds refer to long-term non-healing wounds of the skin and soft tissues surrounding the anus, often resulting from surgery or complications of chronic diseases. Current treatment mainly focuses on maintaining an open wound environment and allowing healing to follow its natural course. Due to the specific anatomical location, susceptibility to secondary infection, and the local wound environment, healing often requires more than 4 weeks. Vacuum-sealed drainage (VSD), combined with counter-current irrigation technology, has been widely adopted and demonstrated significant efficacy in specialties such as burn and plastic surgery, orthopedics, and general surgery. This non-invasive negative-pressure technology offers new approaches for treating refractory perianal wounds, promoting active intervention in the healing process, accelerating healing speed, improving healing quality, and reducing patient discomfort. This article describes the management and application details of this technology for refractory perianal wounds, including methods of outer-film application at different positions, differences in negative-pressure settings based on wound distance from the anal margin, and strategies to avoid secondary contamination. This methodology may facilitate broader clinical adoption of VSD for perianal refractory wounds and presents new therapeutic opportunities for managing such challenging non-healing wounds.
C1 [Li, Meng; Wu, Fan; Ding, Yang; Zhang, Bei; Ding, Kang] Nanjing Univ Chinese Med, Nanjing Hosp Chinese Med, Nanjing, Peoples R China.
   [Du, Jun] Nanjing Univ Chinese Med, Suzhou Tradit Chinese Med Hosp, Nanjing, Peoples R China.
C3 Nanjing University of Chinese Medicine; Nanjing University of Chinese
   Medicine
RP Li, M; Ding, K (通讯作者)，Nanjing Univ Chinese Med, Nanjing Hosp Chinese Med, Nanjing, Peoples R China.
EM limeng740316@163.com; fsyy00237@njucm.edu.cn
FU Planning and Finance Department Project of the National Administration
   of Traditional Chinese Medicine [GZY-GCS-2025-006]; Jiangsu Provincial
   Center for T.C.M. Innovations; Jiangsu Administration of Chinese
   Medicine
FX Financial support for this study was provided by the Planning and
   Finance Department Project of the National Administration of Traditional
   Chinese Medicine (Grant No. GZY-GCS-2025-006). Additional support was
   received from the Jiangsu Provincial Center for T.C.M. Innovations and
   the Jiangsu Administration of Chinese Medicine.
CR Almughamsi AM, 2025, SURG TODAY, V55, P457, DOI 10.1007/s00595-025-02995-2
   Artlett Carol M, 2023, Fibrosis (Hong Kong), V1, DOI [10.35534/fibrosis.2023.10008, 10.35534/fibrosis.2023.10008]
   Chen Y, 2023, MILITARY MED RES, V10, DOI 10.1186/s40779-023-00473-9
   Dai Y., 2026, FRONT IMMUNOL, V16
   Dormer KJ, 2022, WOUNDS, V34, P254, DOI 10.25270/wnds/21101
   Duan X., 2025, FRONT IMMUNOL, V16
   Esmaeili E, 2026, NANOMED-NANOTECHNOL, V72, DOI 10.1016/j.nano.2026.102905
   Fernández IS, 2025, UPDATES SURG, V77, P1067, DOI 10.1007/s13304-025-02270-6
   Fertala Andrzej, 2026, Subcell Biochem, V113, P343, DOI 10.1007/978-3-032-05273-5_11
   Gandhi ND, 2026, SURG CLIN N AM, V106, P51, DOI 10.1016/j.suc.2025.08.012
   Haalboom M, 2018, CURR MED CHEM, V25, P5772, DOI 10.2174/0929867324666170710120556
   Hemmingsen L. M., 2026, CURR RES PHARM DRUG, V10
   Horch RE, 2021, CHIRURG, V92, P1159, DOI [10.1007/s00104-021-01394-w, 10.1007/s00053-021-00575-9]
   Izadi K, 2005, CLIN PLAST SURG, V32, P209, DOI 10.1016/j.cps.2004.11.011
   Jimenez M., 2025, ANORECTAL FISTULA
   Jin J, 2023, CELL PROLIFERAT, V56, DOI 10.1111/cpr.13493
   Kim PJ, 2020, INT WOUND J, V17, P174, DOI 10.1111/iwj.13254
   Lee YH, 2021, MAT SCI ENG C-MATER, V118, DOI 10.1016/j.msec.2020.111385
   Miller-Mikolajczyk C, 2024, ADV WOUND CARE, V13, P375, DOI 10.1089/wound.2023.0115
   Nagy I, 2026, ORVOSI HETILAP, V167, P109, DOI 10.1556/650.2026.33460
   Oneto P, 2021, PLATELETS, V32, P189, DOI 10.1080/09537104.2020.1849605
   Pallaske F, 2018, J WOUND CARE, V27, P692, DOI 10.12968/jowc.2018.27.10.692
   Percival SL, 2011, WOUND REPAIR REGEN, V19, P767, DOI 10.1111/j.1524-475X.2011.00739.x
   Powers JG, 2016, J AM ACAD DERMATOL, V74, P607, DOI 10.1016/j.jaad.2015.08.070
   Reza L, 2024, COLORECTAL DIS, V26, P145, DOI 10.1111/codi.16741
   Sanchez-Haro E, 2025, SURG INFECT, V26, P707, DOI 10.1177/10962964251369451
   Smith SR, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011193.pub2
   Son B, 2025, INT J MOL SCI, V26, DOI 10.3390/ijms262411950
   Tang Y, 2026, FRONT CELL DEV BIOL, V13, DOI 10.3389/fcell.2025.1730032
   Wilkinson HN, 2020, OPEN BIOL, V10, DOI 10.1098/rsob.200223
   Yang L, 2020, Zhonghua Shao Shang Za Zhi, V36, P730, DOI 10.3760/cma.j.cn501120-20190621-00281
   Yin XL, 2023, INT WOUND J, V20, P1033, DOI 10.1111/iwj.13956
   Zhang C, 2019, J DIABETES RES, V2019, DOI 10.1155/2019/5920676
   Zhou CG, 2020, STEM CELL RES THER, V11, DOI 10.1186/s13287-020-01636-4
NR 34
TC 0
Z9 0
U1 1
U2 1
PU JOURNAL OF VISUALIZED EXPERIMENTS
PI CAMBRIDGE
PA 1 ALEWIFE CENTER, STE 200, CAMBRIDGE, MA 02140 USA
SN 1940-087X
J9 JOVE-J VIS EXP
JI J. Vis. Exp.
PD MAR
PY 2026
IS 229
AR e69888
DI 10.3791/69888
PG 9
WC Multidisciplinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Science & Technology - Other Topics
GA FZ9KT
UT WOS:001731384200005
PM 41941407
DA 2026-07-24
ER

PT J
AU Kim, KE
   Jeong, JY
   Park, TJ
   Kim, IH
AF Kim, Ko Eun
   Jeong, Jae Yeong
   Park, Tae Jun
   Kim, Il-Hwan
TI A Case of Malignant Transformation of Solitary Recurrent Cylindroma on
   Scalp
SO ANNALS OF DERMATOLOGY
LA English
DT Article
DE Adenoid cystic carcinoam; Malignant adenoid cystic carcinoma; Mohs
   surgery; Negative-pressure wound therapy
ID PRESSURE WOUND THERAPY
AB A 78-year-old male presented with an asymptomatic pinkish multi-nodular mass on his frontal scalp. The lesion had recurred twice after incomplete surgical excision. Initial punch biopsy was diagnosed with cylindroma. He revisited after one year with exophytic enlargement of the mass, and two staged Mohs micrographic surgery identified well-differentiated malignant cylindroma. Histopathology in the lower dermis and periosteal layer showed atypical cells with mitosis and hyperchromatic nucleoli with increased Ki-67 index of 10% to 30%. The postoperative wound was successfully treated with negative wound pressure therapy (NPWT) and secondary intentional healing. We report this case showing malignant transformation of solitary cylindroma, and good result for secondary intention healing using NPWT for postoperative defect.
C1 [Kim, Ko Eun; Jeong, Jae Yeong; Park, Tae Jun; Kim, Il-Hwan] Korea Univ, Dept Dermatol, Ansan Hosp, 123 Jeokgeum Ro, Ansan 15355, South Korea.
C3 Korea University; Korea University Medicine (KU Medicine)
RP Kim, IH (通讯作者)，Korea Univ, Dept Dermatol, Ansan Hosp, 123 Jeokgeum Ro, Ansan 15355, South Korea.
EM kumcihk@korea.ac.kr
RI ; Kim, Ko Eun/AER-3267-2022
OI JEONG, JAEYEONG/0000-0003-0272-3563; Park, Tae Jun/0000-0001-7610-7670;
   Kim, Ko Eun/0000-0002-4141-204X; Kim, Il-Hwan/0000-0002-4225-002X
CR Bansal Cherry, 2012, Indian J Dermatol, V57, P141, DOI 10.4103/0019-5154.94289
   Cai SS, 2017, INT WOUND J, V14, P661, DOI 10.1111/iwj.12665
   Cunningham T, 2014, DERMATOL SURG, V40, pS120, DOI 10.1097/DSS.0000000000000113
   DONNER LR, 1995, AM J DERMATOPATH, V17, P169, DOI 10.1097/00000372-199504000-00009
   Durani BK, 2001, BRIT J DERMATOL, V145, P653, DOI 10.1046/j.1365-2133.2001.04460.x
   Foreman RK, 2019, FITZPATRICKS DERMATO, P1820
   Kim Stephanie M, 2019, JPRAS Open, V21, P1, DOI 10.1016/j.jpra.2019.04.003
   Kuklani RM, 2009, HEAD NECK PATHOL, V3, P315, DOI 10.1007/s12105-009-0138-x
   Pereira S, 2017, J SURG CASE REP, DOI 10.1093/jscr/rjx122
   Riot S, 2015, PALLIATIVE MED, V29, P470, DOI 10.1177/0269216314560009
NR 10
TC 2
Z9 2
U1 0
U2 1
PU KOREAN DERMATOLOGICAL ASSOC
PI SEOUL
PA 305 SEOCHO NASAN, SUITE OFFICE 1330-16, SEOCHO-2-DONG, SEOCHO-GU, SEOUL,
   137-858, SOUTH KOREA
SN 1013-9087
EI 2005-3894
J9 ANN DERMATOL
JI Ann. Dermatol.
PD DEC
PY 2022
VL 34
IS 6
BP 478
EP 481
DI 10.5021/ad.20.118
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 9Q1SN
UT WOS:000944751900010
PM 36478431
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Tian, M
   Wang, XQ
   Xiao, YR
   Lu, SL
   Jiang, YZ
AF Tian, Ming
   Wang, Xiqiao
   Xiao, Yurui
   Lu, Shuliang
   Jiang, Yuzhi
TI A Rare Case of Diabetic Hand Ulcer Caused by Streptococcus
   agalactiae
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE diabetic hand ulcer; Streptococcus agalactiae; negative pressure wound
   therapy
ID FOOT ULCERS
AB This study reports the case of a 71-year-old woman with type 2 diabetes whose paronychia rapidly progressed to the right middle finger and then to the whole dorsal aspect necrosis of the right hand. After admission, the diagnosis of diabetic hand ulcer was established and Streptococcus agalactiae found as the pathogen. The authors controlled glucose, used 3% hydrogen peroxide and sulfadiazine silver in routine dressing, as well as surgical debridement, topical negative pressure, and skin grafting. The wound closed in 32 days after surgery. Diabetic hand ulcer is often developed from a small wound. The wound, if neglected, will expand very quickly and may lead to amputation and even death. So early diagnosis, standardized treatment, and postoperative rehabilitation is very important.
C1 [Tian, Ming; Wang, Xiqiao; Xiao, Yurui; Lu, Shuliang; Jiang, Yuzhi] Shanghai Jiao Tong Univ, Shanghai 200025, Peoples R China.
C3 Shanghai Jiao Tong University
RP Jiang, YZ (通讯作者)，Shanghai Jiao Tong Univ, Rui Jin Hosp, Sch Med, Shanghai Burns Inst, 197 Rui Jin Er Rd, Shanghai 200025, Peoples R China.
EM yuzhi.jiang@hotmail.com
OI Tian, Ming/0000-0003-1665-321X
FU National Natural Science Foundation of China [30700871, 30600645,
   81071568, 2005CB522603]
FX The author(s) disclosed receipt of the following financial support for
   the research, authorship, and/or publication of this article: Supported
   by the National Natural Science Foundation of China (30700871, 30600645,
   81071568, 2005CB522603).
CR AKINTEWE TA, 1983, TROP GEOGR MED, V35, P353
   Archibald LK, 1997, DIABETIC MED, V14, P607, DOI 10.1002/(SICI)1096-9136(199707)14:7<607::AID-DIA395>3.0.CO;2-G
   Gill GV, 1998, LANCET, V351, P113, DOI 10.1016/S0140-6736(05)78146-0
   Houshian S, 2006, INT J INFECT DIS, V10, P315, DOI 10.1016/j.ijid.2005.06.009
   Lipsky BA, 2012, CLIN INFECT DIS, V54, P1679, DOI [10.1093/cid/cis460, 10.1093/cid/cis346]
   MANN RJ, 1977, J TRAUMA, V17, P376, DOI 10.1097/00005373-197705000-00008
   Tiwari S, 2008, INT J DIABETES DEV C, V28, P130, DOI 10.4103/0973-3930.45273
   Unachukwu C, 2007, DIABETES RES CLIN PR, V75, P148, DOI 10.1016/j.diabres.2006.05.016
   Wang C, 2010, DIABETIC MED, V27, P848, DOI 10.1111/j.1464-5491.2010.03012.x
NR 9
TC 4
Z9 5
U1 0
U2 11
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD SEP
PY 2012
VL 11
IS 3
SI SI
BP 174
EP 176
DI 10.1177/1534734612457032
PG 3
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 010EX
UT WOS:000309078600011
PM 22863692
DA 2026-07-24
ER

PT J
AU Pierson, RC
   Scott, NP
   Briscoe, KE
   Haas, DM
AF Pierson, Rebecca C.
   Scott, Nicole P.
   Briscoe, Kristin E.
   Haas, David M.
TI A review of post-caesarean infectious morbidity: how to prevent and
   treat
SO JOURNAL OF OBSTETRICS AND GYNAECOLOGY
LA English
DT Review
DE Caesarean section; wound infection; surgical site infection
ID SURGICAL SITE INFECTION; PRESSURE WOUND THERAPY;
   MATERNAL-FETAL-MEDICINE; CESAREAN DELIVERY; RISK-FACTORS; OBESE WOMEN;
   GLYCEMIC CONTROL; SKIN CLOSURE; COMPLICATIONS; MANAGEMENT
AB Post-caesarean infectious complications result in significant maternal morbidity and mortality as well as increased readmissions and increased health care cost worldwide. This review provides a discussion of several risk factors that have been identified which predispose women to post-surgical infection. We also provide an overview of strategies for infection prevention including antibiotics, surgical techniques and negative pressure wound therapy. Criteria for diagnosis of wound infection are provided, as well as appropriate treatment regimens. Given the impact of maternal post caesarean infection, it is important for women's health care providers to understand how to prevent these infections, as well as recognise and treat them.
C1 [Pierson, Rebecca C.] Univ Louisville, Dept Obstet Gynecol & Womens Hlth, Ambulatory Care Bldg,2nd Floor Bridge, Louisville, KY 40202 USA.
   [Scott, Nicole P.; Haas, David M.] Indiana Univ, Dept Obstet & Gynecol, Indianapolis, IN 46204 USA.
   [Briscoe, Kristin E.] Univ Florida, Dept Obstet & Gynecol, Gainesville, FL 32611 USA.
C3 University of Louisville; Indiana University System; Indiana University
   Indianapolis; State University System of Florida; University of Florida
RP Pierson, RC (通讯作者)，Univ Louisville, Dept Obstet Gynecol & Womens Hlth, Ambulatory Care Bldg,2nd Floor Bridge, Louisville, KY 40202 USA.
EM rebecca.pierson@louisville.edu
OI Pierson, Rebecca C/0000-0002-6688-8829; Haas, David/0000-0002-8379-0743
CR Ahmadzia HK, 2015, OBSTET GYNECOL, V126, P708, DOI 10.1097/AOG.0000000000001064
   Alanis MC, 2010, AM J OBSTET GYNECOL, V203, DOI 10.1016/j.ajog.2010.06.049
   American College of Obstetricians and Gynecologists, 2011, OBSTET GYNECOLOGY, V117, P472
   [Anonymous], 2004, COCHRANE DATABASE SY, DOI DOI 10.1002/14651858.CD004663.PUB2
   [Anonymous], COCHRANE DATABASE SY
   Arabshahi Kamran Soltani, 2006, Int Wound J, V3, P59, DOI 10.1111/j.1742-4801.2006.00176.x
   Baharestani MM, 2011, INT WOUND J, V8, P118, DOI 10.1111/j.1742-481X.2010.00756.x
   Bowler PG, 2001, CLIN MICROBIOL REV, V14, P244, DOI 10.1128/CMR.14.2.244-269.2001
   Cardile AP, 2014, J SURG RES, V192, P692, DOI 10.1016/j.jss.2014.07.019
   Chauhan SP, 2001, AM J OBSTET GYNECOL, V185, P349, DOI 10.1067/mob.2001.116729
   Cliby WA, 2002, CLIN OBSTET GYNECOL, V45, P507, DOI 10.1097/00003081-200206000-00021
   Corvaglia L, 2016, J PEDIATR GASTR NUTR, V62, P304, DOI 10.1097/MPG.0000000000000928
   CUNNINGHAM FG, 1983, OBSTET GYNECOL, V62, P151
   Daykan Y, 2017, AM J OBSTET GYNECOL, V216, DOI 10.1016/j.ajog.2017.01.009
   Declercq E, 2007, OBSTET GYNECOL, V109, P669, DOI 10.1097/01.AOG.0000255668.20639.40
   Dotters-Katz SK, 2016, J MATERN-FETAL NEO M, V29, P1541, DOI 10.3109/14767058.2015.1058773
   Duff P, 2010, OBSTET GYNECOL, V116, P1393, DOI 10.1097/AOG.0b013e3181fae763
   Echebiri NC, 2015, OBSTET GYNECOL, V125, P299, DOI 10.1097/AOG.0000000000000634
   Ezechi Oliver C, 2009, BMC Res Notes, V2, P186, DOI 10.1186/1756-0500-2-186
   Faro C, 2008, INFECT DIS CLIN N AM, V22, P653, DOI 10.1016/j.idc.2008.05.005
   Fitzwater JL, 2014, OBSTET GYN CLIN N AM, V41, P671, DOI 10.1016/j.ogc.2014.08.008
   GIBBS RS, 1978, OBSTET GYNECOL, V52, P193
   Gyte GM, 2014, COCHRANE DB SYST REV, V11
   Haas D M, 2014, COCHRANE DATABASE SY, pCD007892
   Hamilton SM, 2013, CLIN INFECT DIS, V57, P870, DOI 10.1093/cid/cit282
   Hammad IA, 2014, J MATERN-FETAL NEO M, V27, P463, DOI 10.3109/14767058.2013.818970
   Johnston RC, 2017, J MATERN-FETAL NEO M, V30, P267, DOI 10.3109/14767058.2016.1173672
   Jones Daniel de Alcântara, 2016, Rev. bras. ortop., V51, P646, DOI [10.1016/j.rboe.2016.10.014, 10.1016/j.rboe.2016.10.014]
   Kassebaum NJ, 2014, LANCET, V384, P980, DOI 10.1016/S0140-6736(14)60696-6
   Lazar HL, 2004, CIRCULATION, V109, P1497, DOI 10.1161/01.CIR.0000121747.71054.79
   Lee I, 2010, INFECT CONT HOSP EP, V31, P1219, DOI 10.1086/657134
   Leth RA, 2011, ACTA OBSTET GYN SCAN, V90, P501, DOI 10.1111/j.1600-0412.2011.01090.x
   Lo Torto F, 2017, INT WOUND J, V14, P909, DOI 10.1111/iwj.12725
   Mackeen AD, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009516.pub2
   Mackeen AD, 2015, AM J OBSTET GYNECOL, V212, DOI 10.1016/j.ajog.2014.12.020
   Maggio L, 2015, OBSTET GYNECOL, V125, P1205, DOI 10.1097/AOG.0000000000000789
   Mark KS, 2014, SURG INNOV, V21, P345, DOI 10.1177/1553350613503736
   MARTENS MG, 1995, J REPROD MED, V40, P171
   Molina G, 2015, JAMA-J AM MED ASSOC, V314, P2263, DOI 10.1001/jama.2015.15553
   Ngai IM, 2015, OBSTET GYNECOL, V126, P1251, DOI 10.1097/AOG.0000000000001118
   OBERG MS, 1987, AM J DIS CHILD, V141, P27, DOI 10.1001/archpedi.1987.04460010027015
   Olsen MA, 2010, INFECT CONT HOSP EP, V31, P276, DOI 10.1086/650755
   Ousey K, 2016, J WOUND CARE, V25, P122, DOI 10.12968/jowc.2016.25.3.122
   OWEN J, 1994, CLIN OBSTET GYNECOL, V37, P842, DOI 10.1097/00003081-199412000-00009
   Patel N, 2010, J ANTIMICROB CHEMOTH, V65, P2285, DOI 10.1093/jac/dkq323
   Pergialiotis V, 2017, BRIT J OBSTET GYNAEC, V38, P42
   Schneid-Kofman N, 2005, INT J GYNECOL OBSTET, V90, P10, DOI 10.1016/j.ijgo.2005.03.020
   Schrufer-Poland TL, 2016, EUR J OBSTET GYN R B, V206, P53, DOI 10.1016/j.ejogrb.2016.07.501
   Shree R, 2016, AM J PERINAT, V33, P157, DOI 10.1055/s-0035-1563548
   Spong CY, 2012, OBSTET GYNECOL, V120, P1181, DOI [10.1097/AOG.0b013e3182704880, 10.1097/aog.0b013e3182704880]
   Stevens DL, 2014, CLIN INFECT DIS, V59, pE10, DOI [10.1093/cid/ciu296, 10.1093/cid/ciu444]
   Stevenson T R, 1976, JACEP, V5, P17, DOI 10.1016/S0361-1124(76)80160-8
   Suliburk JW, 2003, J TRAUMA, V55, P1155, DOI 10.1097/01.TA.0000100218.03754.6A
   Svensjö T, 2000, PLAST RECONSTR SURG, V106, P602, DOI 10.1097/00006534-200009030-00012
   Swank ML, 2015, AM J OBSTET GYNECOL, V213, DOI 10.1016/j.ajog.2015.05.030
   Swift SH, 2015, J REPROD MED, V60, P211
   Tabor OB, 1998, CLIN ORTHOP RELAT R, P117
   Tran TS, 2000, OBSTET GYNECOL, V95, P367, DOI 10.1016/S0029-7844(99)00540-2
   Tuuli MG, 2016, AM J OBSTET GYNECOL, V215, DOI 10.1016/j.ajog.2016.05.012
   Tuuli MG, 2016, NEW ENGL J MED, V374, P647, DOI 10.1056/NEJMoa1511048
   van Ramshorst Gabrielle H, 2010, Surg Technol Int, V19, P111
   Vermeulen H., 2004, Cochrane Database Syst. Rev., V2004, DOI [DOI 10.1002/14651858.CD003554.PUB2, 10.1002/14651858.cd003554.pub2]
   WALTERS MD, 1990, OBSTET GYNECOL, V76, P597
   Wang HY, 2016, J MATERN-FETAL NEO M, V29, P3705, DOI 10.3109/14767058.2016.1141886
   Young CNJ, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000005397
   Young OM, 2015, AM J OBSTET GYNECOL, V213, DOI 10.1016/j.ajog.2015.06.034
   Zaki MN, 2016, J PERINATOL, V36, P819, DOI 10.1038/jp.2016.89
NR 67
TC 15
Z9 19
U1 0
U2 3
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 0144-3615
EI 1364-6893
J9 J OBSTET GYNAECOL
JI J. Obstet. Gynaecol.
PY 2018
VL 38
IS 5
BP 591
EP 597
DI 10.1080/01443615.2017.1394281
PG 7
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA GK8BQ
UT WOS:000436441700001
PM 29433350
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Demmer, W
   Aranda, IM
   Wiggenhauser, PS
   Braig, D
   Gilbert, F
   Giunta, R
AF Demmer, Wolfram
   Aranda, Irene Mesas
   Wiggenhauser, Paul Severin
   Braig, David
   Gilbert, Fabian
   Giunta, Riccardo
TI Multidrug-resistant bacterial colonisation in Ukrainian war injuries: a
   need for multimodal therapy
SO HANDCHIRURGIE MIKROCHIRURGIE PLASTISCHE CHIRURGIE
LA German
DT Article
DE complex injury; war injuries; free flap; infection; reconstruction of
   the lower limb
AB This case report describes the interdisciplinary treatment of a complex shrapnel injury to the right femur of an 18-year-old Ukrainian soldier. This open multifragmentary fractur of the femur with a large bone defect, soft tissue damage and osteomyelitis was complicated by several multidrug-resistant bacteria, including Acinetobacter baumanii, which could not be eradicated by antibiotic treatment. Sterility was only achieved by multiple radical debridement and by negative pressure wound therapy with instillation (NPWTi) using hypochlorous acid. The femur was then reconstructed with a chimeric double-barrel fibula free flap. This report highlights the importance of multimodal antimicrobial wound treatments in an era of increasing antibiotic resistance to enable a successful und functional reconstruction of complex and infected fractures.
C1 [Demmer, Wolfram; Aranda, Irene Mesas; Wiggenhauser, Paul Severin; Braig, David; Giunta, Riccardo] LMU Munchen, LMU Klinikum, Abt Hand Plast & Asthet Chirurg, Munich, Germany.
   [Gilbert, Fabian] LMU Munchen, LMU Klinikum, Klin Orthopadie & Unfallchirurg, Munich, Germany.
   [Aranda, Irene Mesas] LMU Klinikum Munchen, Abt Hand Plast & Asthet Chirurg, Ziemsenstr 5, D-80336 Munich, Germany.
C3 University of Munich; University of Munich; University of Munich
RP Aranda, IM (通讯作者)，LMU Klinikum Munchen, Abt Hand Plast & Asthet Chirurg, Ziemsenstr 5, D-80336 Munich, Germany.
EM irenemesas.ar97@gmail.com
RI ; Giunta, Riccardo/JVN-5790-2024; Wiggenhauser, Paul/QQY-2593-2026
OI Demmer, Wolfram/0000-0001-7893-3976; 
CR Allen D, 2014, INT WOUND J, V11, P198, DOI 10.1111/j.1742-481X.2012.01073.x
   Chen CJ, 2016, INT J MOL SCI, V17, DOI 10.3390/ijms17071161
   Day A, 2017, ADV SKIN WOUND CARE, V30, P543, DOI 10.1097/01.ASW.0000526607.80113.66
   Günther F, 2021, J INFECT PREVENT, V22, P12, DOI 10.1177/1757177420963829
   Heppert V, 2005, TRAUMA BERUFSKRANKH, V7, pS110, DOI 10.1007/s10039-004-0910-9
   JONES NF, 1988, PLAST RECONSTR SURG, V81, P378, DOI 10.1097/00006534-198803000-00011
   Kramer M., 2023, SCHUSS EXPLOSIONSWUN
   TAYLOR GI, 1975, PLAST RECONSTR SURG, V56, P243, DOI 10.1097/00006534-197509000-00001
   TAYLOR GI, 1975, PLAST RECONSTR SURG, V55, P533, DOI 10.1097/00006534-197505000-00002
   Wang L, 2007, J Burns Wounds, V6, pe5
NR 10
TC 0
Z9 1
U1 0
U2 1
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 0722-1819
EI 1439-3980
J9 HANDCHIR MIKROCHIR P
JI Handchir. Mikrochir. Plast. Chir.
PD DEC
PY 2023
VL 55
IS 06
BP 457
EP 461
DI 10.1055/a-2108-8978
EA OCT 2023
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AH4W5
UT WOS:001091383700001
PM 37813349
DA 2026-07-24
ER

PT J
AU Siang, KCC
   Fauzi, AA
   Hasnan, N
AF Siang, Kelvin Cheng Chek
   Fauzi, Aishah Ahmad
   Hasnan, Nazirah
TI Diagnostic dilemma of sacral abscess presented with seizure and altered
   conscious level in a patient with spinal cord injury
SO JOURNAL OF SPINAL CORD MEDICINE
LA English
DT Article
DE Sacral abscess; Septicaemia; Pressure ulcer; Spinal cord injury
ID PRESSURE ULCERS
AB Context: Infection and septicaemia may clinically presented with seizure and altered conscious level. In spinal cord injury (SCI) population, they are at risk of having pressure ulcer which can be complicated further with infection and septicaemia.
   Findings: A 40-year-old man with complete T4 SCI and multiple clean and non-healing pressure ulcers at sacral and bilateral ischial tuberosity regions was initially admitted for negative pressure wound therapy (NPWT) dressing. He had an episode of seizure and subsequently had fluctuating altered conscious level before the diagnosis of deep-seated sacral abscess was made and managed. Prior investigations to rule out common possible sources of infections and management did not resolve the fluctuating event of altered consciousness.
C1 [Siang, Kelvin Cheng Chek; Fauzi, Aishah Ahmad; Hasnan, Nazirah] Univ Malaya, Dept Rehabil, Fac Med, Kuala Lumpur 50603, Malaysia.
C3 Universiti Malaya
RP Fauzi, AA (通讯作者)，Univ Malaya, Dept Rehabil, Fac Med, Kuala Lumpur 50603, Malaysia.
EM aishah_fauzi@um.edu.my
RI Hasnan, Nazirah/M-5081-2017; /B-8194-2010
OI Hasnan, Nazirah/0000-0002-5775-428X; 
CR Hauptfleisch J, 2013, ARCH PHYS MED REHAB, V94, P1107, DOI 10.1016/j.apmr.2012.11.012
   Honigman L, 2012, J EMERG MED, V42, P569, DOI 10.1016/j.jemermed.2011.07.033
   Montgomerie JZ, 1997, CLIN INFECT DIS, V25, P1285, DOI 10.1086/516144
   Ruan CM, 1998, ARCH PHYS MED REHAB, V79, P1080, DOI 10.1016/S0003-9993(98)90175-7
   Simpson MA, 2009, J CLIN NEUROSCI, V16, P1682, DOI 10.1016/j.jocn.2009.03.040
NR 5
TC 1
Z9 1
U1 0
U2 5
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND
SN 1079-0268
EI 2045-7723
J9 J SPINAL CORD MED
JI J. Spinal Cord. Med.
PY 2017
VL 40
IS 1
BP 113
EP 117
DI 10.1080/10790268.2015.1133016
PG 5
WC Clinical Neurology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology
GA EL5FX
UT WOS:000394648100017
PM 26871508
DA 2026-07-24
ER

PT J
AU Aragón-Sánchez, J
   Cano-Jimenez, F
   Lazaro-Martinez, JL
   Campillo-Vilorio, N
   Quintana-Marrero, Y
   Hernandez-Herrero, MJ
AF Aragon-Sanchez, Javier
   Cano-Jimenez, Francisco
   Lázaro-Martínez, Jose L.
   Campillo-Vilorio, Nalini
   Quintana-Marrero, Yurena
   Hernández-Herrero, Maria J.
TI Never Amputate a Patient With Diabetes Without Consulting With a
   Specialized Unit
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article
DE diabetic foot; osteomyelitis; diabetic foot infection; critical
   ischaemia; limb salvage
ID SURGICAL-TREATMENT; FOOT OSTEOMYELITIS; MANAGEMENT; ULCERS
AB This study presents a case report of a patient who underwent a severe infection following revascularization because dry necrosis became infected. A major amputation had been indicated because the infection did not respond to antibiotics and advanced wound care with topical negative pressure wound therapy with silver. The patient did not accept the major amputation and attended the authors' specialized unit. Persistent osteomyelitis was diagnosed with a simple X-ray, a cheap tool. Local surgery, antibiotics, appropriate wound care, and split-skin grafting achieved limb salvage in 12 weeks in this patient who had been scheduled for major amputation. Major amputation in patients with an infected foot can sometimes be avoided by correct diagnosis of infection and managing appropriately with specialized support.
C1 [Aragon-Sanchez, Javier] La Paloma Hosp, Diabet Foot Unit, Dept Surg, Las Palmas Gran Canaria 35005, Canary Islands, Spain.
   [Lázaro-Martínez, Jose L.] Complutense Univ Podiatr Clin, Madrid, Spain.
   [Campillo-Vilorio, Nalini] Plaza de la Salud Gen Hosp, Santo Domingo, Dominican Rep.
RP Aragón-Sánchez, J (通讯作者)，La Paloma Hosp, Diabet Foot Unit, Dept Surg, C Maestro Valle 20, Las Palmas Gran Canaria 35005, Canary Islands, Spain.
EM javiaragon@telefonica.net
RI LAZARO MARTINEZ, JOSE LUIS/AAE-2268-2021; Aragón-Sánchez,
   Javier/AAR-9727-2021
OI LAZARO MARTINEZ, JOSE LUIS/0000-0001-6110-0265; Campillo-Vilorio,
   Nalini/0009-0009-8521-4262; Aragón-Sánchez, Javier/0000-0001-6307-5040
CR Aragón-Sánchez FJ, 2008, DIABETOLOGIA, V51, P1962, DOI 10.1007/s00125-008-1131-8
   Aragón-Sánchez J, 2011, DIABETIC MED, V28, P1249, DOI 10.1111/j.1464-5491.2011.03367.x
   Aragón-Sánchez J, 2011, INT J LOW EXTR WOUND, V10, P33, DOI 10.1177/1534734611400259
   Aragón-Sánchez J, 2010, INT J LOW EXTR WOUND, V9, P37, DOI 10.1177/1534734610361949
   Aragón-Sánchez J, 2009, INT J LOW EXTR WOUND, V8, P141, DOI 10.1177/1534734609344106
   Berendt AR, 2008, DIABETES-METAB RES, V24, pS190, DOI 10.1002/dmrr.853
   Faglia E, 1998, J DIABETES COMPLICAT, V12, P96, DOI 10.1016/S1056-8727(97)98004-1
   Faglia Ezio, 2006, J Foot Ankle Surg, V45, P220, DOI 10.1053/j.jfas.2006.04.002
   Fisher TK, 2010, J AM PODIAT MED ASSN, V100, P401, DOI 10.7547/1000401
   Fisher TK, 2010, J VASC SURG, V52, p72S, DOI 10.1016/j.jvs.2010.06.011
   Hartemann-Heurtier A, 2002, DIABETES METAB, V28, P477
   Henke PK, 2005, ANN SURG, V241, P885, DOI 10.1097/01.sla.0000164172.28918.3f
   Kowalski TJ, 2011, J FOOT ANKLE SURG, V50, P171, DOI 10.1053/j.jfas.2010.12.009
   Nehler MR, 1999, J VASC SURG, V30, P509, DOI 10.1016/S0741-5214(99)70078-9
   Norgren L, 2007, J VASC SURG, V45, pS5, DOI 10.1016/j.jvs.2006.12.037
   Ramanujam Crystal L, 2010, Foot Ankle Spec, V3, P231, DOI 10.1177/1938640010375114
   TAYLOR LM, 1987, J VASC SURG, V6, P454, DOI 10.1067/mva.1987.avs0060454
   Zgonis Thomas, 2008, Foot Ankle Spec, V1, P46, DOI 10.1177/1938640007312316.
NR 18
TC 7
Z9 7
U1 0
U2 2
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD DEC
PY 2011
VL 10
IS 4
BP 214
EP 217
DI 10.1177/1534734611424649
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 864RP
UT WOS:000298258000007
PM 21994213
DA 2026-07-24
ER

PT J
AU Patané, F
   Zingarelli, E
   Sansone, F
   Cappuccio, G
   Rinaldi, M
AF Patane, Francesco
   Zingarelli, Edoardo
   Sansone, Fabrizio
   Cappuccio, Gianfranco
   Rinaldi, Mauro
TI Vacuum-assisted sternal closure after a 'depression induced ischemic
   test' in severe mediastinitis
SO JOURNAL OF CARDIOVASCULAR MEDICINE
LA English
DT Article
DE mediastinitis; sternal wound infection; vacuum assisted sternal closure
ID POSTSTERNOTOMY MEDIASTINITIS; MANAGEMENT
AB We present a case of a 71-year-old patient with arterial myocardial revascularization and postoperative course complicated with sternal wound diastasis and subsequent mediastinitis. The patient underwent double revision of the mediastinum: the first in 13th and the second in 27th with total sternectomy. Although the resulting external exposure of pericardial cavity and grafts is a contraindication for using vacuum-assisted closure (VAC), we used it after a 'depression induced ischemic test' (DIIT) to evaluate ischemic threshold. After the VAC therapy period (from 32nd to 112th postoperative day), the sternal wound was ready to close. We think that VAC-therapy is a safe and economic approach in the treatment of serious substance loss even with pericardial cavity and graft exposure.
C1 [Patane, Francesco; Zingarelli, Edoardo; Sansone, Fabrizio; Rinaldi, Mauro] San Giovanni Battista Hosp, Dept Cardiac Surg, I-10126 Turin, Italy.
   [Cappuccio, Gianfranco] Villa Serena Hosp, Div Cardiovasc Rehabil, Turin, Italy.
C3 A.O.U. Citta della Salute e della Scienza di Torino; AOU San Giovanni
   Battista-Molinette
RP Patané, F (通讯作者)，San Giovanni Battista Hosp, Dept Cardiac Surg, C So Bramante 88, I-10126 Turin, Italy.
EM f_patane@hotmail.com
RI Patane, Francesco/AAW-9473-2021
OI Rinaldi, Mauro/0000-0002-7092-8619
CR Catarino PA, 2000, ANN THORAC SURG, V70, P1891, DOI 10.1016/S0003-4975(00)02173-1
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Sjögren J, 2005, ANN THORAC SURG, V80, P1270, DOI 10.1016/j.athoracsur.2005.04.010
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
NR 6
TC 1
Z9 1
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1558-2027
J9 J CARDIOVASC MED
JI J. Cardiovasc. Med.
PD JUN
PY 2008
VL 9
IS 6
BP 622
EP 624
DI 10.2459/JCM.0b013e3282f226ee
PG 3
WC Cardiac & Cardiovascular Systems
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA 305UX
UT WOS:000256204400012
PM 18475132
DA 2026-07-24
ER

PT J
AU Symeonidou, E
   Gkoutziotis, I
   Moulazimi, A
   Lagopoulos, V
   Kamparoudis, A
AF Symeonidou, Elissavet
   Gkoutziotis, Ioannis
   Moulazimi, Anastasia
   Lagopoulos, Vasileios
   Kamparoudis, Apostolos
TI Necrotizing Fasciitis of the Breast: A Case Series and Review of the
   Literature
SO SURGICAL INFECTIONS
LA English
DT Review
DE breast; debridement; mastectomy; necrotizing fasciitis; sepsis; surgical
   infections
ID SOFT-TISSUE INFECTION; CLINICAL PRESENTATION; MORTALITY; RARE;
   DETERMINANTS; LIMB
AB Background: Primary necrotizing fasciitis of the breast is a rare clinical condition and therefore a challenge for the clinical doctor. Its severity is associated with high morbidity and mortality.
   Patients and Methods: In the current article we present three cases that we treated in our surgical department with a combination of empirical antibiotic treatment, complete surgical debridement in stages, and negative pressure wound therapy.
   Conclusions: It appears that prompt diagnosis and surgical intervention are key for the successful management of these cases. The recognition of early clinical signs as well as risk factors are issues of great importance. A high index of suspicion is required for the early diagnosis and treatment, aiming to the best outcome for the patient.
C1 [Symeonidou, Elissavet; Gkoutziotis, Ioannis; Moulazimi, Anastasia; Lagopoulos, Vasileios; Kamparoudis, Apostolos] Aristotle Univ Thessaloniki, Ippokratio Gen Hosp Thessaloniki, Dept Surg 5, Thessaloniki, Greece.
   [Symeonidou, Elissavet] Aristotle Univ Thessaloniki, Ippokratio Gen Hosp Thessaloniki, Dept Surg 5, Konstantinoupoleos 49, Thessaloniki 54642, Greece.
C3 Aristotle University of Thessaloniki; Aristotle University of
   Thessaloniki
RP Symeonidou, E (通讯作者)，Aristotle Univ Thessaloniki, Ippokratio Gen Hosp Thessaloniki, Dept Surg 5, Konstantinoupoleos 49, Thessaloniki 54642, Greece.
EM ellie.simeonidou@gmail.com
RI Lagopoulos, Vasileios/AAP-5018-2021; SYMEONIDOU, ELISSAVET/JBJ-8273-2023
OI Lagopoulos, Vasileios/0000-0002-2366-3283; 
CR Ablett DJ, 2012, SCOTT MED J, V57, P1, DOI [DOI 10.1258/SMJ.2011.011283, 10.1258/smj.2011.011283]
   ALShareef B, 2018, CASE REP SURG, V2018, DOI 10.1155/2018/1370680
   Anaya DA, 2005, ARCH SURG-CHICAGO, V140, P151, DOI 10.1001/archsurg.140.2.151
   Angarita FA, 2014, BREAST CANCER-TOKYO, V21, P108, DOI 10.1007/s12282-010-0219-4
   Cai YC, 2021, SURG INFECT, V22, P363, DOI 10.1089/sur.2020.071
   Childers BJ, 2002, AM SURGEON, V68, P109
   Dodaro CA, 2020, AM J CASE REP, V21, DOI 10.12659/AJCR.922688
   Elliott DC, 1996, ANN SURG, V224, P672, DOI 10.1097/00000658-199611000-00011
   Eugster T, 1997, Swiss Surg, V3, P117
   Fayman K, 2017, INT J SURG CASE REP, V31, P221, DOI 10.1016/j.ijscr.2017.01.049
   Flandrin A, 2009, BREAST J, V15, P199, DOI 10.1111/j.1524-4741.2009.00697.x
   Gehlen JMLG, 2008, BREAST J, V14, P199, DOI 10.1111/j.1524-4741.2007.00556.x
   GIULIANO A, 1977, AM J SURG, V134, P52, DOI 10.1016/0002-9610(77)90283-5
   Hasham S, 2005, BMJ-BRIT MED J, V330, P830, DOI 10.1136/bmj.330.7495.830
   Hoeffel JC, 2002, PLAST RECONSTR SURG, V109, P2165, DOI 10.1097/00006534-200205000-00073
   Islam S, 2021, CUREUS J MED SCIENCE, V13, DOI 10.7759/cureus.19886
   Jallali N, 2003, J Wound Care, V12, P297
   Keune JD, 2009, BREAST J, V15, P321, DOI 10.1111/j.1524-4741.2009.00731.x
   Konik RD, 2020, PLAST SURG-CHIR PLAS, V28, P215, DOI 10.1177/2292550320928557
   Lee J, 2015, ANN SURG TREAT RES, V89, P102, DOI 10.4174/astr.2015.89.2.102
   Lee TC, 2007, AM J SURG, V194, P809, DOI 10.1016/j.amjsurg.2007.08.047
   Maduba CC, 2020, J SURG CASE REP, DOI 10.1093/jscr/rjz397
   Marks B, 2019, INT J SURG CASE REP, V65, P10, DOI 10.1016/j.ijscr.2019.10.020
   Marongiu F, 2017, INT WOUND J, V14, P349, DOI 10.1111/iwj.12607
   MCHENRY CR, 1995, ANN SURG, V221, P558, DOI 10.1097/00000658-199505000-00013
   Mersil M, 2021, CUREUS J MED SCIENCE, V13, DOI 10.7759/cureus.17891
   Murphy BL, 2018, J SURG RES, V228, P263, DOI 10.1016/j.jss.2018.03.045
   Nizami S, 2006, BREAST J, V12, P168, DOI 10.1111/j.1075-122X.2006.00227.x
   Özalay M, 2006, FOOT ANKLE INT, V27, P598, DOI 10.1177/107110070602700806
   Rajakannu M, 2006, BREAST J, V12, P266, DOI 10.1111/j.1075-122X.2006.00253.x
   Rieger UM, 2007, ANN PLAS SURG, V58, P523, DOI 10.1097/01.sap.0000244978.27053.08
   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
   Shah J, 2001, BRIT J PLAST SURG, V54, P67, DOI 10.1054/bjps.2000.3461
   Singh G, 2002, EUR J SURG, V168, P366, DOI 10.1080/11024150260284897
   Trent Jennifer T, 2002, Adv Skin Wound Care, V15, P135, DOI 10.1097/00129334-200205000-00010
   Velchuru VR, 2006, BREAST J, V12, P72, DOI 10.1111/j.1075-122X.2006.00186.x
   Ward ND, 2017, BREAST J, V23, P95, DOI 10.1111/tbj.12686
   WARD RG, 1991, BRIT J SURG, V78, P488, DOI 10.1002/bjs.1800780431
   Wong CH, 2004, CRIT CARE MED, V32, P1535, DOI 10.1097/01.CCM.0000129486.35458.7D
   Wong CH, 2003, J BONE JOINT SURG AM, V85A, P1454, DOI 10.2106/00004623-200308000-00005
   Yousfi Jaouad, 2021, Eur J Case Rep Intern Med, V8, P002434, DOI [10.12890/2021_002434, 10.12890/2021_002434]
NR 41
TC 3
Z9 3
U1 0
U2 1
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD FEB
PY 2023
VL 24
IS 1
BP 19
EP 26
DI 10.1089/sur.2022.282
EA DEC 2022
PG 8
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA W4IU5
UT WOS:000905557000001
PM 36580649
DA 2026-07-24
ER

PT J
AU Stroock, AD
   Cabodi, M
AF Stroock, AD
   Cabodi, M
TI Microfluidic biomaterials
SO MRS BULLETIN
LA English
DT Article
DE biological; biomedical; fluidics; microscale; soft lithography; tissue
ID VACUUM-ASSISTED CLOSURE; HYDROGELS; MICROFABRICATION; SYSTEMS; WOUNDS;
   GELS
AB Biomedical applications-prostheses, tissue engineering, drug delivery, and wound healing-demand increasingly sophisticated characteristics from the materials that come into contact with living systems in the laboratory and the clinic. With the development of microfluidics, there is an opportunity to create active biomaterials based on embedded microfluidic structures. These structures allow for control of the concentrations of soluble chemicals and hydrodynamic stresses within the material and at its interfaces, and thus allow one to tailor the environment experienced by the living tissue. In this article, we review initial efforts to develop these microfluidic biomaterials and present considerations regarding the required characteristics of the materials and of the microfluiclic-mediated mass transfer. As specific examples, we present work toward microfluidic control of mass transfer in scaffolds for tissue engineering and in wound dressings.
RI Stroock, Abraham/HTM-5976-2023
OI Stroock, Abraham/0000-0002-8145-9977
CR Beebe DJ, 2000, P NATL ACAD SCI USA, V97, P13488, DOI 10.1073/pnas.250273097
   Boontheekul T, 2005, BIOMATERIALS, V26, P2455, DOI 10.1016/j.biomaterials.2004.06.044
   Borenstein JT, 2002, BIOMED MICRODEVICES, V4, P167, DOI 10.1023/A:1016040212127
   Burdick JA, 2002, BIOMATERIALS, V23, P4315, DOI 10.1016/S0142-9612(02)00176-X
   Cabodi M, 2005, J AM CHEM SOC, V127, P13788, DOI 10.1021/ja054820t
   CABODI M, 2005, ASME SUMM BIOENG C V
   Chang SCN, 2001, J BIOMED MATER RES, V55, P503, DOI 10.1002/1097-4636(20010615)55:4<503::AID-JBM1043>3.0.CO;2-S
   COLTON CK, 1995, CELL TRANSPLANT, V4, P415, DOI 10.1016/0963-6897(95)00025-S
   Fidkowski C, 2005, TISSUE ENG, V11, P302, DOI 10.1089/ten.2005.11.302
   Fournier RonaldL., 1998, BASIC TRANSPORT PHEN
   King KR, 2004, ADV MATER, V16, P2007, DOI 10.1002/adma.200306522
   LABARBERA M, 1990, SCIENCE, V249, P992, DOI 10.1126/science.2396104
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   Langer R., 2000, PRINCIPLES TISSUE EN
   Liu Q, 2000, BIOMATERIALS, V21, P2163, DOI 10.1016/S0142-9612(00)00137-X
   Martin I, 2004, TRENDS BIOTECHNOL, V22, P80, DOI 10.1016/j.tibtech.2003.12.001
   Mayer M, 2004, PROTEOMICS, V4, P2366, DOI 10.1002/pmic.200300748
   McDonald JC, 2002, ANAL CHEM, V74, P1537, DOI 10.1021/ac010938q
   MORYKWAS MJ, 1993, FASEB J, V7, pA138
   Pins GD, 2000, FASEB J, V14, P593, DOI 10.1096/fasebj.14.3.593
   Ratner BD, 2004, ANNU REV BIOMED ENG, V6, P41, DOI 10.1146/annurev.bioeng.6.040803.140027
   Rowley JA, 1999, BIOMATERIALS, V20, P45, DOI 10.1016/S0142-9612(98)00107-0
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Tang MD, 2003, J AM CHEM SOC, V125, P12988, DOI 10.1021/ja037677h
   Therriault D, 2005, ADV MATER, V17, P395, DOI 10.1002/adma.200400481
   Tsang VL, 2004, ADV DRUG DELIVER REV, V56, P1635, DOI 10.1016/j.addr.2004.05.001
   WEISZ PB, 1973, SCIENCE, V179, P433, DOI 10.1126/science.179.4072.433
NR 27
TC 22
Z9 31
U1 0
U2 17
PU MATERIALS RESEARCH SOCIETY
PI WARRENDALE
PA 506 KEYSTONE DR, WARRENDALE, PA 15086 USA
SN 0883-7694
J9 MRS BULL
JI MRS Bull.
PD FEB
PY 2006
VL 31
IS 2
BP 114
EP 119
DI 10.1557/mrs2006.25
PG 6
WC Materials Science, Multidisciplinary; Physics, Applied
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Materials Science; Physics
GA 014JB
UT WOS:000235474800023
DA 2026-07-24
ER

PT J
AU Volpe, P
   Pucci, G
   Stilo, G
   Alberti, A
   Foti, G
   Surace, R
   Massara, M
AF Volpe, Pietro
   Pucci, Giulia
   Stilo, Giuseppe
   Alberti, Antonino
   Foti, Giovanni
   Surace, Rosangela
   Massara, Mafalda
TI Use of cord blood platelet gel to enhance healing of deep surgical site
   dehiscences after peripheral bypass
SO REGENERATIVE MEDICINE
LA English
DT Article
DE cord blood platelet gel; growth factors; obesity; peripheral bypass;
   surgical site dehiscence; wound healing
ID DIABETIC FOOT ULCERS; RICH PLASMA; VAC THERAPY; REVASCULARIZATION;
   STIMULATION
AB Surgical site dehiscence after lower limb revascularization through bypass represents a serious postoperative complication, especially in diabetic and obese patients, with subsequent risk of early graft failure, infection, sepsis, hemorrhage, major amputation and sometimes death. To prevent bypass exposure and subsequent complications, physicians recur to reoperation, antibiotic therapy, advanced dressing and vacuum-assisted closure therapy. To improve the process of wound healing, cord blood platelet gel can be used to fill deep and large wounds. Growth factors released from platelets in the cord blood platelet gel stimulate the process of healing and allow patients to be followed up in Outpatient Surgery, thus reducing hospital stay and costs, while providing excellent results.
C1 [Volpe, Pietro; Stilo, Giuseppe; Alberti, Antonino; Massara, Mafalda] Grande Osped Metropolitano Bianchi Melacrino More, Unit Vasc & Endovasc Surg, I-89124 Reggio Di Calabria, Italy.
   [Pucci, Giulia; Foti, Giovanni; Surace, Rosangela] Grande Osped Metropolitano Bianchi Melacrino More, Serv Immunohaematol & Transfus Med, Calabria Cord Blood Bank, I-89124 Reggio Di Calabria, Italy.
RP Massara, M (通讯作者)，Grande Osped Metropolitano Bianchi Melacrino More, Unit Vasc & Endovasc Surg, I-89124 Reggio Di Calabria, Italy.
EM drmafaldamassara@gmail.com
RI /AAM-9453-2020
CR Acosta S, 2012, EUR J VASC ENDOVASC, V44, P294, DOI 10.1016/j.ejvs.2012.06.005
   [Anonymous], 2004, BLOOD TRANSFUS
   [Anonymous], 2006, BLOOD TRANSFUS
   Bisceglia G, 2020, REGEN MED, V15, P1171, DOI 10.2217/rme-2019-0074
   Borzini P, 2007, ISBT SCI SERIES
   Chang JK, 2003, ANN VASC SURG, V17, P91, DOI 10.1007/s10016-001-0337-8
   De Caridi G, 2016, INT WOUND J, V13, P759, DOI 10.1111/iwj.12369
   De Caridi G, 2016, INT WOUND J, V13, P754, DOI 10.1111/iwj.12368
   De Caridi G, 2016, INT WOUND J, V13, P336, DOI 10.1111/iwj.12301
   De Caridi G, 2016, INT WOUND J, V13, P220, DOI 10.1111/iwj.12272
   De Caridi G, 2016, INT WOUND J, V13, P72, DOI 10.1111/iwj.12233
   Giles KA, 2010, ANN VASC SURG, V24, P48, DOI 10.1016/j.avsg.2009.05.003
   Lakhiani C, 2019, J VASC SURG CASES IN, V5, P435, DOI 10.1016/j.jvscit.2019.04.008
   Landesberg R, 2000, J ORAL MAXIL SURG, V58, P297, DOI 10.1016/S0278-2391(00)90058-2
   Lee E S, 2000, Surg Infect (Larchmt), V1, P257, DOI 10.1089/109629600750067183
   Mannari RJ, 2002, WOUNDS, V14, P116
   Massara M, 2015, SEMIN VASC SURG, V28, P195, DOI 10.1053/j.semvascsurg.2016.01.002
   Nam JH, 1999, ANN VASC SURG, V13, P77, DOI 10.1007/s100169900224
   Peters EJ, 2001, ARCH PHYS MED REHAB, V82, P721, DOI 10.1053/apmr.2001.23780
   Rebulla P, 2016, BLOOD TRANSFUS-ITALY, V14, P73, DOI 10.2450/2015.0122-15
   Rosso L, 2014, BLOOD TRANSFUS-ITALY, V12, pS235, DOI 10.2450/2013.0214-12
   Tadini Gianluca, 2015, BMJ Case Rep, V2015, DOI [10.1136/bcr-2014-207364, 10.1136/bcr-2014-207364]
   Tadini G, 2015, BLOOD TRANSFUS-ITALY, V13, P153, DOI 10.2450/2014.0160-14
   Veves A, 2001, DIABETES CARE, V24, P290, DOI 10.2337/diacare.24.2.290
   Volpe P, 2017, SEMIN VASC SURG, V30, P106, DOI 10.1053/j.semvascsurg.2017.12.001
NR 25
TC 6
Z9 6
U1 0
U2 8
PU FUTURE MEDICINE LTD
PI LONDON
PA UNITEC HOUSE, 3RD FLOOR, 2 ALBERT PLACE, FINCHLEY CENTRAL, LONDON, N3
   1QB, ENGLAND
SN 1746-0751
EI 1746-076X
J9 REGEN MED
JI Regen. Med.
PD AUG
PY 2020
VL 15
IS 08
BP 1951
EP 1956
DI 10.2217/rme-2020-0034
EA OCT 2020
PG 6
WC Cell & Tissue Engineering; Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Engineering
GA PA4AQ
UT WOS:000583035600001
PM 33118483
DA 2026-07-24
ER

PT J
AU Tatterton, MR
   Homer-Vanniasinkam, S
AF Tatterton, M. R.
   Homer-Vanniasinkam, S.
TI Infections in vascular surgery
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Article
DE Surgical site infection; Prosthetic graft infection; Vascular access
   infection; Prevention; Management; Methicillin-resistant S. aureus
   (MRSA)
ID RESISTANT STAPHYLOCOCCUS-AUREUS; SURGICAL-SITE INFECTIONS; PROSTHETIC
   GRAFT INFECTIONS; SUPPLEMENTAL PERIOPERATIVE OXYGEN; DIALYSIS
   ARTERIOVENOUS GRAFTS; RANDOMIZED-CONTROLLED-TRIALS; VACUUM-ASSISTED
   CLOSURE; WOUND-INFECTION; NASAL CARRIAGE; PROPHYLACTIC ANTIBIOTICS
AB Infections in vascular surgery are usually of multifactorial nature resulting from a complex interplay of patient, surgical and environmental factors. Preventative measures initiated from the stage of pre-operative screening, maintenance of patient homeostasis and the use of organism-directed antibiotics can contribute to reduce infection rates. Graft preservation techniques are becoming increasingly popular as a method to treat established graft infections. In this article we report on the current trends and techniques on the management of infections in vascular surgery. Ongoing studies are required to continue to accumulate data on the effectiveness of these techniques. (C) 2011 Elsevier Ltd. All rights reserved.
C1 [Tatterton, M. R.; Homer-Vanniasinkam, S.] Leeds Gen Infirm, Leeds Vasc Inst, Leeds LS1 3EX, W Yorkshire, England.
C3 Leeds General Infirmary; University of Leeds
RP Homer-Vanniasinkam, S (通讯作者)，Leeds Gen Infirm, Leeds Vasc Inst, Great George St, Leeds LS1 3EX, W Yorkshire, England.
EM mtatterton@doctors.org.uk; shervanthi.homer-vanniasinkam@leedsth.nhs.uk
RI ; Tatterton, Mark/AAX-7640-2021
OI Homer-Vanniasinkam, Shervanthi/0000-0001-6234-5053; 
CR Anderson DJ, 2007, INFECT CONT HOSP EP, V28, P1047, DOI 10.1086/520731
   Anding K, 2003, NEPHROL DIAL TRANSPL, V18, P2067, DOI 10.1093/ndt/gfg330
   [Anonymous], 2008, Brit Med J
   Antonios VS, 2006, J INFECTION, V53, P49, DOI 10.1016/j.jinf.2005.10.004
   Appelbaum PC, 2006, CLIN MICROBIOL INFEC, V12, P16, DOI 10.1111/j.1469-0691.2006.01344.x
   Armstrong PA, 2007, J VASC SURG, V46, P71, DOI 10.1016/j.jvs.2007.02.058
   ATNIP RG, 1991, SURGERY, V110, P106
   Bandyk DF, 2008, SEMIN VASC SURG, V21, P119, DOI 10.1053/j.semvascsurg.2008.05.008
   BANDYK DF, 1984, ARCH SURG-CHICAGO, V119, P102
   Bandyk DF, 2001, J SURG RES, V95, P44, DOI 10.1006/jsre.2000.6035
   Barie Philip S, 2002, Surg Infect (Larchmt), V3 Suppl 1, pS9, DOI 10.1089/sur.2002.3.s1-9
   Belda FJ, 2005, JAMA-J AM MED ASSOC, V294, P2035, DOI 10.1001/jama.294.16.2035
   BERGAMINI TM, 1992, J SURG RES, V52, P101, DOI 10.1016/0022-4804(92)90286-9
   Bode LGM, 2010, NEW ENGL J MED, V362, P9, DOI 10.1056/NEJMoa0808939
   BOELAERT JR, 1993, NEPHROL DIAL TRANSPL, V8, P235
   Bozorgzadeh A, 1999, AM J SURG, V177, P125, DOI 10.1016/S0002-9610(98)00317-1
   Bratzler DW, 2004, CLIN INFECT DIS, V38, P1706, DOI 10.1086/421095
   BUNT TJ, 1986, AM SURGEON, V52, P472
   Bunt TJ, 2001, CARDIOVASC SURG, V9, P225, DOI 10.1016/S0967-2109(00)00104-6
   CALLIGARO KD, 1991, SURGERY, V110, P805
   CALLIGARO KD, 1992, AM J SURG, V164, P291, DOI 10.1016/S0002-9610(05)81090-6
   Cantlon CA, 2006, AM J INFECT CONTROL, V34, P526, DOI 10.1016/j.ajic.2006.04.206
   CHERRY KJ, 1992, J VASC SURG, V46, P71
   Chonchol M, 2006, SEMIN DIALYSIS, V19, P291, DOI 10.1111/j.1525-139X.2006.00175.x
   CITAK MS, 1992, J SURG RES, V52, P127, DOI 10.1016/0022-4804(92)90292-8
   Claeys LGY, 2002, J VASC SURG, V35, P1287, DOI 10.1067/mva.2002.122026
   CLASSEN DC, 1992, NEW ENGL J MED, V326, P281, DOI 10.1056/NEJM199201303260501
   COBURN MC, 1994, J VASC SURG, V20, P896, DOI 10.1016/0741-5214(94)90226-7
   Cowie Scott E, 2005, Vasc Endovascular Surg, V39, P327, DOI 10.1177/153857440503900404
   CRUSE PJE, 1980, SURG CLIN N AM, V60, P27
   Darouiche RO, 2010, NEW ENGL J MED, V362, P18, DOI 10.1056/NEJMoa0810988
   Demaria RG, 2003, J CARDIOVASC SURG, V44, P757
   Dohmen PM, 2008, J HOSP INFECT, V70, P15, DOI 10.1016/S0195-6701(08)60019-5
   Dosluoglu HH, 2010, J VASC SURG, V51, P1160, DOI 10.1016/j.jvs.2009.11.053
   EARNSHAW JJ, 1988, ANN ROY COLL SURG, V70, P139
   Earnshaw JJ, 2002, EUR J VASC ENDOVASC, V24, P283, DOI 10.1053/ejvs.2002.1705
   Edmiston CE, 2006, AM J SURG, V192, P344, DOI 10.1016/j.amjsurg.2006.04.009
   Engemann JJ, 2003, CLIN INFECT DIS, V36, P592, DOI 10.1086/367653
   Engin C, 2005, TEX HEART I J, V32, P529
   FLETCHER JP, 1991, AUST NZ J SURG, V61, P432, DOI 10.1111/j.1445-2197.1991.tb00257.x
   Foley RN, 2004, J AM SOC NEPHROL, V15, P1038, DOI 10.1097/01.ASN.0000119144.95922.C4
   Forbes SS, 2008, J AM COLL SURGEONS, V207, P336, DOI 10.1016/j.jamcollsurg.2008.03.014
   Fridkin SK, 1999, CLIN CHEST MED, V20, P303, DOI 10.1016/S0272-5231(05)70143-X
   Fry D., 2006, Surgical Infections, V7, pS17
   Gagliardi AR, 2009, AM J INFECT CONTROL, V37, P398, DOI 10.1016/j.ajic.2008.10.027
   Gao H, 2010, EUR J VASC ENDOVASC, V39, P472, DOI 10.1016/j.ejvs.2009.11.023
   Giacometti A, 2000, J ANTIMICROB CHEMOTH, V46, P751, DOI 10.1093/jac/46.5.751
   Giacometti A, 2002, ANTIMICROB AGENTS CH, V46, P2885, DOI 10.1128/AAC.46.9.2885-2888.2002
   Goeau-Brissonniere O, 1991, Ann Vasc Surg, V5, P408, DOI 10.1007/BF02133043
   Goëau-Brissonnière OA, 2002, J VASC SURG, V35, P1260, DOI 10.1067/mva.2002.121980
   Graffunder EM, 2002, J ANTIMICROB CHEMOTH, V49, P999, DOI 10.1093/jac/dkf009
   GRECO RS, 1982, ANN SURG, V195, P168, DOI 10.1097/00000658-198202000-00008
   Greif R, 2000, NEW ENGL J MED, V342, P161, DOI 10.1056/NEJM200001203420303
   Hadamitzky CD, 2007, J CARDIOVASC SURG, V48, P477
   HASSELGREN PO, 1984, ANN SURG, V200, P86
   Hawn MT, 2008, J AM COLL SURGEONS, V206, P814, DOI 10.1016/j.jamcollsurg.2007.12.013
   Hernández-Richter T, 2003, EUR J VASC ENDOVASC, V26, P550, DOI 10.1016/S1078-5884(03)00344-7
   Hicks RCJ, 1997, EUR J VASC ENDOVASC, V14, P5, DOI 10.1016/S1078-5884(97)80143-8
   Hirth RA, 1996, JAMA-J AM MED ASSOC, V276, P1303
   Homer-Vanniasinkam S, 2007, INT J INFECT DIS, V11, pS17, DOI 10.1016/S1201-9712(07)60003-4
   Hopkins SP, 2000, ANN VASC SURG, V14, P532, DOI 10.1007/s100169910101
   Humphreys H, 2009, J HOSP INFECT, V73, P316, DOI 10.1016/j.jhin.2009.03.028
   Jorda-Marcos R, 2007, MYCOSES, V50, P302, DOI 10.1111/j.1439-0507.2007.01366.x
   KAISER AB, 1978, ANN SURG, V188, P283, DOI 10.1097/00000658-197809000-00003
   Katsamouris AN, 2000, ANN VASC SURG, V14, P444, DOI 10.1007/s100169910087
   KIKTA MJ, 1987, J VASC SURG, V5, P566, DOI 10.1067/mva.1987.avs0050566
   KIMMEL RM, 1994, ANN PLAS SURG, V32, P623, DOI 10.1097/00000637-199406000-00011
   Kirkland KB, 1999, INFECT CONT HOSP EP, V20, P725, DOI 10.1086/501572
   Kluytmans J, 1998, J HOSP INFECT, V40, pS25, DOI 10.1016/S0195-6701(98)90201-8
   Kluytmans JAJW, 1996, INFECT CONT HOSP EP, V17, P793
   Kluytmans JAJW, 1996, INFECT CONT HOSP EP, V17, P780
   Koskas F, 1996, Cardiovasc Surg, V4, P495, DOI 10.1016/0967-2109(95)00126-3
   Kudva A, 1997, Semin Vasc Surg, V10, P184
   Kurz A, 1996, NEW ENGL J MED, V334, P1209, DOI 10.1056/NEJM199605093341901
   Kusachi Shinya, 2008, Journal of Infection and Chemotherapy, V14, P44, DOI 10.1007/s10156-007-0574-z
   Laupland KB, 2003, CLIN INFECT DIS, V37, P933, DOI 10.1086/377735
   Leaper David J, 2004, Int Wound J, V1, P247, DOI 10.1111/j.1742-4801.2004.00067.x
   Lehnhardt FJ, 2002, EUR J VASC ENDOVASC, V23, P127, DOI 10.1053/ejvs.2001.1571
   LONGFIELD JN, 1985, INFECT CONT HOSP EP, V6, P445, DOI 10.1017/S0195941700064791
   LORENTZEN JE, 1985, SURGERY, V98, P81
   MAGEE C, 1976, AM J SURG, V131, P547, DOI 10.1016/0002-9610(76)90007-6
   MAILLOUX LU, 1991, AM J KIDNEY DIS, V18, P326, DOI 10.1016/S0272-6386(12)80091-6
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Manian FA, 2003, CLIN INFECT DIS, V36, P863, DOI 10.1086/368195
   Mariani PG, 2006, J ANTIMICROB CHEMOTH, V58, P481, DOI 10.1093/jac/dkl256
   Matsuura JH, 2000, ANN VASC SURG, V14, P50, DOI 10.1007/s100169910009
   Murad MH, 2008, J VASC SURG, V48, p34S, DOI 10.1016/j.jvs.2008.08.044
   NAGACHINTA T, 1987, J INFECT DIS, V156, P967, DOI 10.1093/infdis/156.6.967
   Nasim A, 2001, EUR J VASC ENDOVASC, V22, P211, DOI 10.1053/ejvs.2001.1429
   Nassar GM, 2001, KIDNEY INT, V60, P1, DOI 10.1046/j.1523-1755.2001.00765.x
   Naylor AR, 2001, EUR J VASC ENDOVASC, V21, P289, DOI 10.1053/ejvs.2001.1311
   Neumayer L, 2007, J AM COLL SURGEONS, V204, P1178, DOI 10.1016/j.jamcollsurg.2007.03.022
   *NIH, 2004, US REN DAT SYST USRD
   OBRIEN T, 1992, BRIT J SURG, V79, P1262, DOI 10.1002/bjs.1800791205
   Owens CD, 2008, J HOSP INFECT, V70, P3, DOI 10.1016/S0195-6701(08)60017-1
   Padberg FT Jr, 2008, J VASC SURG, V48, p55S, DOI 10.1016/j.jvs.2008.08.067
   PALDER SB, 1985, ANN SURG, V202, P235, DOI 10.1097/00000658-198508000-00015
   PARRAS F, 1995, ANTIMICROB AGENTS CH, V39, P175, DOI 10.1128/AAC.39.1.175
   Perera Ganesha B, 2006, Vasc Endovascular Surg, V40, P1, DOI 10.1177/153857440604000101
   Perl TM, 1998, ANN PHARMACOTHER, V32, pS7, DOI 10.1177/106002809803200104
   Perl TM, 2002, NEW ENGL J MED, V346, P1871, DOI 10.1056/NEJMoa003069
   PERLER BA, 1991, SURGERY, V110, P30
   PIANO G, 1995, SURG CLIN N AM, V75, P799, DOI 10.1016/S0039-6109(16)46700-9
   PITT HA, 1980, ANN SURG, V192, P356, DOI 10.1097/00000658-198009000-00011
   Pittas AG, 2004, ARCH INTERN MED, V164, P2005, DOI 10.1001/archinte.164.18.2005
   Pounds Lori L, 2005, Vasc Endovascular Surg, V39, P511
   Qadan M, 2009, ARCH SURG-CHICAGO, V144, P359, DOI 10.1001/archsurg.2009.1
   Raza Z, 1999, EUR J VASC ENDOVASC, V17, P5, DOI 10.1053/ejvs.1998.0651
   REAGAN DR, 1991, ANN INTERN MED, V114, P101, DOI 10.7326/0003-4819-114-2-101
   Ryan SV, 2004, J VASC SURG, V39, P73, DOI 10.1016/j.jvs.2003.07.002
   Sacar M, 2005, J SURG RES, V129, P329, DOI 10.1016/j.jss.2005.05.017
   Sacar M, 2007, J SURG RES, V139, P170, DOI 10.1016/j.jss.2006.10.003
   Saleem BR, 2010, AM J SURG, V200, P47, DOI 10.1016/j.amjsurg.2009.05.018
   Schanzer A, 2008, J VASC SURG, V48, P655, DOI 10.1016/j.jvs.2008.04.030
   SCHMITT DD, 1986, J VASC SURG, V3, P732, DOI 10.1067/mva.1986.avs0030732
   Schutte WP, 2007, AM J SURG, V193, P385, DOI 10.1016/j.amjsurg.2006.09.028
   Schwab DP, 2000, ANN VASC SURG, V14, P63, DOI 10.1007/s100169910011
   Scriven JM, 2003, EUR J VASC ENDOVASC, V25, P147, DOI 10.1053/ejvs.2002.1829
   Seeger JM, 2000, AM SURGEON, V66, P166
   Sicard GA, 1997, EUR J VASC ENDOVASC, V14, P93, DOI 10.1016/S1078-5884(97)80163-3
   Smyth ETM, 2008, J HOSP INFECT, V69, P230, DOI 10.1016/j.jhin.2008.04.020
   Spartera C, 1997, EUR J VASC ENDOVASC, V14, P24, DOI 10.1016/S1078-5884(97)80148-7
   Stevenson KB, 2002, AM J KIDNEY DIS, V39, P549, DOI 10.1053/ajkd.2002.31405
   Svensson S, 2008, EUR J VASC ENDOVASC, V36, P84, DOI 10.1016/j.ejvs.2007.12.020
   SZILAGYI DE, 1972, ANN SURG, V176, P321, DOI 10.1097/00000658-197209000-00008
   TABBARA MR, 1995, ANN VASC SURG, V9, P378, DOI 10.1007/BF02139410
   TAYLOR B, 1993, AM J SURG, V165, P632, DOI 10.1016/S0002-9610(05)80450-7
   Taylor Michelle D, 2004, Surg Infect (Larchmt), V5, P180
   Taylor SM, 1996, AM SURGEON, V62, P188
   Taylor SM, 1996, ANN VASC SURG, V10, P117, DOI 10.1007/BF02000754
   Tokars JI, 2002, AM J INFECT CONTROL, V30, P288, DOI 10.1067/mic.2002.120904
   TORSELLO G, 1993, J VASC SURG, V17, P768, DOI 10.1016/0741-5214(93)90124-5
   Treiman GS, 2001, J VASC SURG, V33, P948, DOI 10.1067/mva.2001.114209
   Tsiodras S, 2001, LANCET, V358, P207, DOI 10.1016/S0140-6736(01)05410-1
   van Rijen MML, 2008, J ANTIMICROB CHEMOTH, V61, P254, DOI 10.1093/jac/dkm480
   *VASC ACC WORK GRO, 1997, AM J KIDNEY DIS S, V30, P150
   Vogel TR, 2008, J VASC SURG, V47, P264, DOI 10.1016/j.jvs.2007.10.030
   von Eiff C, 2001, NEW ENGL J MED, V344, P11, DOI 10.1056/NEJM200101043440102
   WALTZ P, 2005, ANN VASC SURG, V19, P84
   WENZEL RP, 1995, J HOSP INFECT, V31, P13, DOI 10.1016/0195-6701(95)90079-9
   Wertheim HFL, 2004, LANCET, V364, P703, DOI 10.1016/S0140-6736(04)16897-9
   Williams IM, 2003, EUR J VASC ENDOVASC, V25, P390, DOI 10.1053/ejvs.2002.1890
   Wilson S E, 2001, Surg Infect (Larchmt), V2, P171, DOI 10.1089/109629601750469492
   WORNING AM, 1986, J ANTIMICROB CHEMOTH, V17, P105, DOI 10.1093/jac/17.1.105
   Yasim A, 2006, EUR J VASC ENDOVASC, V31, P274, DOI 10.1016/j.ejvs.2005.09.018
   ZIBARI GB, 1988, SURGERY, V104, P681
NR 146
TC 23
Z9 27
U1 0
U2 3
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0020-1383
EI 1879-0267
J9 INJURY
JI Injury-Int. J. Care Inj.
PD DEC
PY 2011
VL 42
SU 5
BP S35
EP S41
DI 10.1016/S0020-1383(11)70131-0
PG 7
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA 866IB
UT WOS:000298372900008
PM 22196909
DA 2026-07-24
ER

PT J
AU Shen, B
   Kochhar, G
   Navaneethan, U
   Liu, XL
   Farraye, FA
   Gonzalez-Lama, Y
   Bruining, D
   Pardi, DS
   Lukas, M
   Bortlik, M
   Wu, KC
   Sood, A
   Schwartz, DA
   Sandborn, WJ
AF Shen, Bo
   Kochhar, Gursimran
   Navaneethan, Udayakumar
   Liu, Xiuli
   Farraye, Francis A.
   Gonzalez-Lama, Yago
   Bruining, David
   Pardi, Darrell S.
   Lukas, Martin
   Bortlik, Martin
   Wu, Kaicun
   Sood, Ajit
   Schwartz, David A.
   Sandborn, William J.
CA Global Interventional Inflammatory
TI Role of interventional inflammatory bowel disease in the era of biologic
   therapy: a position statement from the Global Interventional IBD Group
SO GASTROINTESTINAL ENDOSCOPY
LA English
DT Review
ID ENDOSCOPIC BALLOON DILATION; CHRONIC ULCERATIVE-COLITIS; VACUUM-ASSISTED
   CLOSURE; EXPANDABLE METAL STENT; CROHNS-DISEASE; SUBMUCOSAL DISSECTION;
   INTESTINAL STRICTURES; ANASTOMOTIC STRICTURE; MUCOSAL RESECTION; FIBRIN
   GLUE
AB Interventional (or therapeutic) inflammatory bowel disease (IBD) endoscopy has an expanding role in the treatment of disease and surgical adverse events. Endoscopic therapy has been explored and used in the management of strictures, fistulas/abscesses, colitis-associated neoplasia, postsurgical acute or chronic leaks, and obstructions. The endoscopic therapeutic modalities include balloon dilation, stricturotomy, stent placement, fistulotomy, fistula injection and clipping, sinusotomy, EMR, and endoscopic submucosal dissection. With a better understanding of the disease course of IBD, improved long-term impact of medical therapy, and advances in endoscopic technology, we can foresee interventional IBD becoming an integrated part of the multidisciplinary approach to patients with complex IBD.
C1 [Shen, Bo] Cleveland Clin, Dept Gastroenterol & Hepatol, Cleveland, OH 44106 USA.
   [Kochhar, Gursimran] Allegheny Gen Hosp, Div Gastroenterol, Pittsburgh, PA 15212 USA.
   [Navaneethan, Udayakumar] Florida Hosp, Ctr Intervent Endoscopy, Orlando, FL USA.
   [Liu, Xiuli] Univ Florida, Dept Pathol & Lab Med, Gainesville, FL USA.
   [Farraye, Francis A.] Boston Univ, Med Ctr, Div Gastroenterol, Boston, MA USA.
   [Gonzalez-Lama, Yago] Hosp Univ Puerta de Hierro, Serv Gastroenterol & Hepatol, Madrid, Spain.
   [Bruining, David; Pardi, Darrell S.] Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN USA.
   [Lukas, Martin; Bortlik, Martin] Univ Karlovy, Iekarska Fak, Div Gastroenerol, Prague, Czech Republic.
   [Wu, Kaicun] Xijin Hosp, Dept Gastroenterol, Xian, Shaanxi, Peoples R China.
   [Sood, Ajit] Dayanand Med Coll, Dept Gastroenterol, Ludhiana, Punjab, India.
   [Schwartz, David A.] Vanderbilt Univ, Med Ctr, Dept Gastroenterol, Nashville, TN USA.
   [Sandborn, William J.] Univ Calif San Diego, Med Ctr, Div Gastroenterol, 225 Dickinson St, San Diego, CA 92103 USA.
C3 Cleveland Clinic Foundation; Allegheny Health Network; Allegheny General
   Hospital; Adventist Health Services; AdventHealth; State University
   System of Florida; University of Florida; Boston University; Hospital
   Puerta de Hierro-Majadahonda; Mayo Clinic; Charles University Prague;
   Dayanand Medical College & Hospital; Vanderbilt University; University
   of California System; University of California San Diego
RP Shen, B (通讯作者)，Cleveland Clin, Digest Dis & Surg Inst A31, Intervent IBD Unit, 9500 Euclid Ave, Cleveland, OH 44195 USA.
EM shenb@ccf.org
RI Bortlík, Martin/G-2769-2017; Sandborn, William/ABE-8342-2020; Lukáš,
   Martin/J-6382-2017; Kochhar, Gursimran/AAN-2045-2020
OI Lukáš, Martin/0000-0003-3946-3953; 
CR Adegbola SO, 2017, INT J COLORECTAL DIS, V32, P1539, DOI 10.1007/s00384-017-2899-0
   Ali UA, 2012, DIS COLON RECTUM, V55, P541, DOI 10.1097/DCR.0b013e318244087c
   [Anonymous], 2003, GASTROINTEST ENDOSC, V58, pS3
   [Anonymous], INFLAMM BOWEL DIS
   [Anonymous], INFLAMM BOWEL DIS
   [Anonymous], ENDOSCOPY
   Atreja A, 2014, J CROHNS COLITIS, V8, P392, DOI 10.1016/j.crohns.2013.10.001
   Attar A, 2012, INFLAMM BOWEL DIS, V18, P1849, DOI 10.1002/ibd.22844
   Axelrad JE, 2018, CLIN GASTROENTEROL H, V16, pXXV, DOI 10.1016/j.cgh.2017.05.016
   Axon A, 2005, ENDOSCOPY, V37, P570, DOI 10.1055/s-2005-861352
   Bettenworth D, 2017, INFLAMM BOWEL DIS, V23, P133, DOI 10.1097/MIB.0000000000000988
   Bickston SJ, 2005, DIS COLON RECTUM, V48, P1081, DOI 10.1007/s10350-004-0865-8
   Branche J, 2012, ENDOSCOPY, V44, pE325, DOI 10.1055/s-0032-1309854
   Burisch J., Gut
   Carballal S, 2018, GUT, V67, P70, DOI 10.1136/gutjnl-2016-312332
   Chen M, 2015, INFLAMM BOWEL DIS, V21, P2222, DOI 10.1097/MIB.0000000000000433
   Chen M, 2014, GASTROINTEST ENDOSC, V80, P353, DOI 10.1016/j.gie.2014.03.039
   Chen M, 2014, GASTROINTEST ENDOSC, V79, P688, DOI 10.1016/j.gie.2013.11.005
   Cosnes J, 2002, INFLAMM BOWEL DIS, V8, P244, DOI 10.1097/00054725-200207000-00002
   Dafnis G, 2007, EUR J GASTROEN HEPAT, V19, P83, DOI 10.1097/MEG.0b013e32801222f9
   de Parades V, 2010, COLORECTAL DIS, V12, P459, DOI 10.1111/j.1463-1318.2009.01811.x
   Di Nardo G, 2010, GASTROINTEST ENDOSC, V72, P1201, DOI 10.1016/j.gie.2010.08.003
   East JE, 2007, CLIN GASTROENTEROL H, V5, P1065, DOI 10.1016/j.cgh.2007.04.013
   EKBOM A, 1990, LANCET, V336, P357, DOI 10.1016/0140-6736(90)91889-I
   EKBOM A, 1990, NEW ENGL J MED, V323, P1228, DOI 10.1056/NEJM199011013231802
   Ellis CN, 2006, DIS COLON RECTUM, V49, P1736, DOI 10.1007/s10350-006-0718-8
   Gardenbroek TJ, 2015, COLORECTAL DIS, V17, P426, DOI 10.1111/codi.12867
   Grimaud JC, 2010, GASTROENTEROLOGY, V138, P2275, DOI 10.1053/j.gastro.2010.02.013
   Gulati S, 2018, INFLAMM BOWEL DIS, V24, P1196, DOI 10.1093/ibd/izx113
   Guo FL, 2016, DIGEST DIS SCI, V61, P2977, DOI 10.1007/s10620-016-4242-y
   Gustavsson A, 2013, ALIMENT PHARM THER, V37, P430, DOI 10.1111/apt.12176
   Hayashi N, 2013, GASTROINTEST ENDOSC, V78, P625, DOI 10.1016/j.gie.2013.04.185
   Hendel J, 2014, UNITED EUR GASTROENT, V2, P406, DOI 10.1177/2050640614547805
   Hong SN, 2017, CLIN ENDOSC, V50, P437, DOI 10.5946/ce.2017.132
   Hurlstone DP, 2007, GUT, V56, P838, DOI 10.1136/gut.2006.106294
   Iacopini F, 2015, GASTROINTEST ENDOSC, V82, P734, DOI 10.1016/j.gie.2015.02.052
   Ikematsu H, 2010, BMC GASTROENTEROL, V10, DOI 10.1186/1471-230X-10-33
   Jess T, 2012, GASTROENTEROLOGY, V143, P375, DOI 10.1053/j.gastro.2012.04.016
   Karstensen JG, 2016, ENDOSC INT OPEN, V4, pE296, DOI 10.1055/s-0042-101940
   Karstensen JG, 2014, ENDOSCOPY, V46, pE227, DOI 10.1055/s-0034-1365382
   Keränen I, 2010, SCAND J GASTROENTERO, V45, P725, DOI 10.3109/00365521003663696
   Keskin M, 2015, SURG LAPARO ENDO PER, V25, P505, DOI 10.1097/SLE.0000000000000216
   Kinoshita S, 2018, GASTROINTEST ENDOSC, V87, P1079, DOI 10.1016/j.gie.2017.10.035
   Kochhar G, 2018, GASTROINTEST ENDOSC, V88, P87, DOI 10.1016/j.gie.2018.02.034
   Kochhar G, 2018, INFLAMM BOWEL DIS, V24, pE14, DOI 10.1093/ibd/izy101
   Kochhar GS, 2017, ENDOSC INT OPEN, V5, pE64, DOI 10.1055/s-0042-121664
   Krauss E, 2014, INT J CLIN EXP PATHO, V7, P7419
   Kudo S, 2000, WORLD J SURG, V24, P1081, DOI 10.1007/s002680010154
   Kudo SE, 1996, GASTROINTEST ENDOSC, V44, P8, DOI 10.1016/S0016-5107(96)70222-5
   Laine L, 2015, GASTROENTEROLOGY, V148, P639, DOI 10.1053/j.gastro.2015.01.031
   Lan N, 2019, GASTROINTEST ENDOSC, V89, P144, DOI 10.1016/j.gie.2018.08.004
   Lan N, 2018, INFLAMM BOWEL DIS, V24, P1510, DOI 10.1093/ibd/izy029
   Lan N, 2018, CLIN GASTROENTEROL H, V16, P1260, DOI 10.1016/j.cgh.2018.02.035
   Lan N, 2018, INFLAMM BOWEL DIS, V24, P897, DOI 10.1093/ibd/izx085
   Lan N, 2017, INFLAMM BOWEL DIS, V23, P502, DOI 10.1097/MIB.0000000000001044
   Levine RA, 2012, INFLAMM BOWEL DIS, V18, P506, DOI 10.1002/ibd.21739
   Li Y, 2015, BRIT J SURG, V102, P1418, DOI 10.1002/bjs.9906
   Lian L, 2018, DIGEST DIS SCI, V63, P1821, DOI 10.1007/s10620-018-5082-8
   Lian L, 2017, CLIN GASTROENTEROL H, V15, P1226, DOI 10.1016/j.cgh.2016.10.030
   Lian L, 2015, DIS COLON RECTUM, V58, P423, DOI 10.1097/DCR.0000000000000322
   Lichtenstein GR, 2006, AM J GASTROENTEROL, V101, P1030, DOI 10.1111/j.1572-0241.2006.00463.x
   Lichtenstein GR, 2006, CLIN GASTROENTEROL H, V4, P621, DOI 10.1016/j.cgh.2006.03.002
   Lindsey I, 2002, DIS COLON RECTUM, V45, P1608, DOI 10.1007/s10350-004-7247-0
   Alastruey CL, 2016, ENDOSC INT OPEN, V4, pE301, DOI 10.1055/s-0042-101786
   Maple JT, 2015, GASTROINTEST ENDOSC, V81, P1311, DOI 10.1016/j.gie.2014.12.010
   Marinello F, 2018, CIR ESPAN, V96, P369, DOI [10.1016/j.cireng.2018.02.015, 10.1016/j.ciresp.2018.02.003]
   Martines G, 2008, INFLAMM BOWEL DIS, V14, P291, DOI 10.1002/ibd.20268
   Matsuhashi N, 2000, GASTROINTEST ENDOSC, V51, P343, DOI 10.1016/S0016-5107(00)70366-X
   Mennigen R, 2015, TECH COLOPROCTOL, V19, P241, DOI 10.1007/s10151-015-1284-7
   Mino-Kenudson M, 2005, AM J SURG PATHOL, V29, P680, DOI 10.1097/01.pas.0000154129.87219.fa
   Morar PS, 2015, ALIMENT PHARM THER, V42, P1137, DOI 10.1111/apt.13388
   Mowat C, 2011, GUT, V60, P571, DOI 10.1136/gut.2010.224154
   Mukewar S, 2014, INFLAMM BOWEL DIS, V20, P2056, DOI 10.1097/MIB.0000000000000154
   Navaneethan U, 2016, SURG ENDOSC, V30, P5434, DOI 10.1007/s00464-016-4902-1
   Navaneethan U, 2014, ENDOSC INT OPEN, V2, pE201, DOI 10.1055/s-0034-1377522
   Navaneethan U, 2012, J CROHNS COLITIS, V6, P470, DOI 10.1016/j.crohns.2011.10.005
   Okamoto K, 2017, DIGEST ENDOSC, V29, P45, DOI 10.1111/den.12863
   Ono Y, 2012, DIGEST ENDOSC, V24, P432, DOI 10.1111/j.1443-1661.2012.01315.x
   Paine E, 2013, GASTROINTEST ENDOSC, V78, P819, DOI 10.1016/j.gie.2013.08.023
   Panés J, 2018, GASTROENTEROLOGY, V154, P1334, DOI 10.1053/j.gastro.2017.12.020
   Panés J, 2016, LANCET, V388, P1281, DOI 10.1016/S0140-6736(16)31203-X
   Prosst R, 2016, TECH COLOPROCTOL, V20, P753, DOI 10.1007/s10151-016-1537-0
   Rao AK, 2016, CLIN GASTROENTEROL H, V14, P568, DOI 10.1016/j.cgh.2015.10.013
   Rejchrt S, 2011, ENDOSCOPY, V43, P911, DOI 10.1055/s-0030-1256405
   Remzi FH, 2015, ANN SURG, V262, P675, DOI 10.1097/SLA.0000000000001386
   Reutemann BA, 2017, INFLAMM BOWEL DIS, V23, P1803, DOI 10.1097/MIB.0000000000001181
   Rieder F, 2016, J CROHNS COLITIS, V10, P873, DOI 10.1093/ecco-jcc/jjw055
   Ritter LA, 2013, JSLS-J SOC LAPAROEND, V17, P481, DOI 10.4293/108680813X13693422521999
   Rodrigues C, 2013, WORLD J GASTRO ENDOS, V5, P265, DOI 10.4253/wjge.v5.i5.265
   Sano Y, 2016, DIGEST ENDOSC, V28, P526, DOI 10.1111/den.12644
   Shah SC, 2016, ALIMENT PHARM THER, V43, P317, DOI 10.1111/apt.13475
   Shah SC, 2016, CLIN GASTROENTEROL H, V14, P1245, DOI 10.1016/j.cgh.2016.01.015
   Shen B, 2004, AM J GASTROENTEROL, V99, P2340, DOI 10.1111/j.1572-0241.2004.40604.x
   Shen B, 2017, GASTROINTEST ENDOSC, V85, P1133, DOI 10.1016/j.gie.2017.01.025
   Shen B, 2011, INFLAMM BOWEL DIS, V17, P2527, DOI 10.1002/ibd.21644
   Singh A, 2017, J CROHNS COLITIS, V11, P1044, DOI 10.1093/ecco-jcc/jjx078
   Small AJ, 2008, SURG ENDOSC, V22, P454, DOI 10.1007/s00464-007-9453-z
   Smith LA, 2008, INFLAMM BOWEL DIS, V14, P1380, DOI 10.1002/ibd.20497
   Suzuki N, 2004, DIS COLON RECTUM, V47, P1201, DOI 10.1007/s10350-004-0556-5
   Suzuki N, 2017, ENDOSCOPY, V49, P1237, DOI 10.1055/s-0043-114410
   Swaminath A, 2008, INFLAMM BOWEL DIS, V14, P213, DOI 10.1002/ibd.20318
   Van Assche G, 2010, GUT, V59, P320, DOI 10.1136/gut.2009.180182
   Verlaan T, 2011, COLORECTAL DIS, V13, P18, DOI 10.1111/j.1463-1318.2011.02775.x
   Vitton V, 2005, ALIMENT PHARM THERAP, V21, P1453, DOI 10.1111/j.1365-2036.2005.02456.x
   Wada H, 2005, Tech Coloproctol, V9, P53, DOI 10.1007/s10151-005-0194-5
   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
   Wholey MH, 1998, AM J SURG, V175, P194, DOI 10.1016/S0002-9610(97)00285-7
   Wibmer AG, 2010, INT J COLORECTAL DIS, V25, P1149, DOI 10.1007/s00384-010-1010-x
   Wu XR, 2013, GASTROINTEST ENDOSC, V78, P875, DOI 10.1016/j.gie.2013.05.021
   Wu XR, 2013, J GASTROINTEST SURG, V17, P1452, DOI 10.1007/s11605-013-2216-3
NR 110
TC 56
Z9 70
U1 0
U2 14
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0016-5107
EI 1097-6779
J9 GASTROINTEST ENDOSC
JI Gastrointest. Endosc.
PD FEB
PY 2019
VL 89
IS 2
BP 215
EP 237
DI 10.1016/j.gie.2018.09.045
PG 23
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA HI0VU
UT WOS:000456163300002
PM 30365985
DA 2026-07-24
ER

PT J
AU Altman, AD
   Robert, M
   Armbrust, R
   Fawcett, WJ
   Nihira, M
   Jones, CN
   Tamussino, K
   Sehouli, J
   Dowdy, SC
   Nelson, G
AF Altman, Alon D.
   Robert, Magali
   Armbrust, Robert
   Fawcett, William J.
   Nihira, Mikio
   Jones, Chris N.
   Tamussino, Karl
   Sehouli, Jalid
   Dowdy, Sean C.
   Nelson, Gregg
TI Guidelines for vulvar and vaginal surgery: Enhanced Recovery After
   Surgery Society recommendations
SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
LA English
DT Article
DE gynecology; Enhanced Recovery After Surgery; ERAS; vaginal surgery;
   vulvar surgery
ID VACUUM-ASSISTED CLOSURE; MECHANICAL BOWEL PREPARATION; MIDURETHRAL SLING
   PROCEDURES; ANTIBIOTIC-PROPHYLAXIS; INGUINAL LYMPHADENECTOMY; VENOUS
   THROMBOEMBOLISM; INGUINOFEMORAL LYMPHADENECTOMY; GROIN LYMPHADENECTOMY;
   POSTMENOPAUSAL WOMEN; POSTOPERATIVE PAIN
AB This is the first collaborative Enhanced Recovery After Surgery Society guideline for optimal perioperative care for vulvar and vaginal surgeries. An Embase and PubMed database search of publications was performed. Studies on each topic within the Enhanced Recovery After Surgery vulvar and vaginal outline were selected, with emphasis on meta-analyses, randomized controlled trials, and prospective cohort studies. All studies were reviewed and graded according to the Grading of Recommendations, Assessment, Development and Evaluation system. All recommendations on the Enhanced Recovery After Surgery topics are based on the best available evidence. The level of evidence for each item is presented.
C1 [Altman, Alon D.] Univ Manitoba, Dept Obstet Gynecol & Reprod Sci, Winnipeg, MB, Canada.
   [Robert, Magali] Cumming Sch Med, Dept Obstet & Gynecol, Calgary, AB, Canada.
   [Armbrust, Robert; Sehouli, Jalid] Charite Univ Med Berlin, European Competence Ctr Ovarian Canc, Ctr Oncol Surg, Dept Gynecol, Berlin, Germany.
   [Fawcett, William J.; Jones, Chris N.] Royal Surrey Cty Hosp, Dept Anaesthesia, Surrey, England.
   [Nihira, Mikio] Univ Calif Riverside, Dept Obstet & Gynecol, Div Female Pelv Med & Reconstruct Surg, Riverside, CA USA.
   [Tamussino, Karl] Med Univ Graz, Div Gynecol, Graz, Austria.
   [Dowdy, Sean C.] Mayo Clin, Div Gynecol Oncol, Coll Med, Rochester, MN USA.
   [Nelson, Gregg] Tom Baker Canc Clin, Div Gynecol Oncol, Calgary, AB, Canada.
C3 University of Manitoba; Free University of Berlin; Humboldt University
   of Berlin; Charite Universitatsmedizin Berlin; Royal Surrey County
   Hospital; University of California System; University of California
   Riverside; Medical University of Graz; Mayo Clinic; University of
   Calgary; Tom Baker Cancer Clinic
RP Altman, AD (通讯作者)，Univ Manitoba, Dept Obstet Gynecol & Reprod Sci, Winnipeg, MB, Canada.
EM alon.altman@cancercare.mb.ca
RI ; Nelson, Gregg/HCH-9224-2022; Jones, Chris/B-2481-2013; Nihira,
   Mikio/IXN-2228-2023
OI Robert, Magali/0000-0001-5429-9843; Nelson, Gregg/0000-0002-8177-1098;
   Jones, Chris/0000-0001-9047-6034; Altman, Alon/0000-0002-6345-4910; 
CR ADELEYE JA, 1976, INT SURG, V61, P467
   Altman AD, 2017, GYNECOL ONCOL, V145, P386, DOI 10.1016/j.ygyno.2017.02.013
   Altman AD, 2011, J OBSTET GYNAECOL CA, V33, P1031, DOI 10.1016/S1701-2163(16)35052-6
   Angioli R, 2014, EUR J OBSTET GYN R B, V177, P67, DOI 10.1016/j.ejogrb.2014.03.041
   [Anonymous], 2018, Obstet Gynecol, V131, P1177, DOI [10.1097/aog.0000000000002672, 10.1097/AOG.0000000000002672]
   Arnold A, 2015, J MINIM INVAS GYN, V22, P737, DOI 10.1016/j.jmig.2015.04.003
   AYELEKE RO, 2017, COCHRANE DB SYST REV, V6, DOI DOI 10.1002/14651858.CD004637.PUB2
   Baggish MS, 2010, ATLAS PELVIC ANATOMY
   Batra RS, 2001, ARCH DERMATOL, V137, P1317
   Blanton E, 2017, AM J OBSTET GYNECOL, V216, P557, DOI 10.1016/j.ajog.2016.12.175
   Bouchot O, 2004, EUR UROL, V45, P761, DOI 10.1016/j.eururo.2003.12.003
   Brady M, 2003, Cochrane Database Syst Rev, pCD004423, DOI 10.1002/14651858.CD004423
   Brindle M, 2020, BJS OPEN, V4, P157, DOI 10.1002/bjs5.50238
   Buchsbaum GM, 2005, AM J OBSTET GYNECOL, V193, P2173, DOI 10.1016/j.ajog.2005.07.093
   Buda A, 2016, EUR J OBSTET GYN R B, V197, P156, DOI 10.1016/j.ejogrb.2015.12.005
   CAPRINI JA, 1991, SEMIN THROMB HEMOST, V17, P304
   Carter-Brooks CM, 2018, AM J OBSTET GYNECOL, V219, DOI 10.1016/j.ajog.2018.06.009
   Charoenkwan K, 2014, COCHRANE DB SYST REV, V2014
   Collawn SS, 2000, PLAST RECONSTR SURG, V105, P2180, DOI 10.1097/00006534-200005000-00044
   Dainty LA, 2005, GYNECOL ONCOL, V97, P949, DOI 10.1016/j.ygyno.2005.03.021
   Dardarian TS, 2006, GYNECOL ONCOL, V101, P140, DOI 10.1016/j.ygyno.2005.10.002
   Denzinger S, 2007, EUR UROL, V51, P1320, DOI 10.1016/j.eururo.2006.12.027
   Dhar R, 2006, J Wound Care, V15, P312
   Doleman B, 2015, ANAESTHESIA, V70, P1186, DOI 10.1111/anae.13179
   Dolin SJ, 2005, BRIT J ANAESTH, V95, P584, DOI 10.1093/bja/aei227
   Fanning J, 2011, AM J OBSTET GYNECOL, V205, P309, DOI 10.1016/j.ajog.2011.05.010
   Feldheiser A, 2016, ACTA ANAESTH SCAND, V60, P289, DOI 10.1111/aas.12651
   Fernández-Guisasola J, 2010, ANAESTHESIA, V65, P379, DOI 10.1111/j.1365-2044.2010.06249.x
   Foster RT, 2007, AM J OBSTET GYNECOL, V197, DOI 10.1016/j.ajog.2007.08.017
   Gaarenstroom KN, 2003, INT J GYNECOL CANCER, V13, P522, DOI 10.1046/j.1525-1438.2003.13304.x
   Glaser GE, 2020, GYNECOL ONCOL, V157, P476, DOI 10.1016/j.ygyno.2020.02.025
   Glavind K, 2007, ACTA OBSTET GYN SCAN, V86, P1122, DOI 10.1080/00016340701505317
   Gould N, 2001, GYNECOL ONCOL, V82, P329, DOI 10.1006/gyno.2001.6266
   Graul A, 2017, INT J GYNECOL CANCER, V27, P581, DOI 10.1097/IGC.0000000000000912
   Greene KA, 2017, AM J OBSTET GYNECOL, V217, DOI 10.1016/j.ajog.2017.04.017
   Groot CAUD, 2004, EUR J OBSTET GYN R B, V114, P77, DOI 10.1016/j.ejogrb.2003.09.018
   Guyatt GH, 2008, BMJ-BRIT MED J, V336, P924, DOI 10.1136/bmj.39489.470347.AD
   Hakvoort RA, 2004, BJOG-INT J OBSTET GY, V111, P828, DOI 10.1111/j.1471-0528.2004.00181.x
   Harmanli O, 2012, INT UROGYNECOL J, V23, P621, DOI 10.1007/s00192-011-1624-8
   Hinten F, 2011, BRIT J CANCER, V105, P1279, DOI 10.1038/bjc.2011.407
   Hokenstad ED, 2016, INT UROGYNECOL J, V27, P1525, DOI 10.1007/s00192-016-2990-z
   Hristovska AM, 2014, ACTA OBSTET GYN SCAN, V93, P233, DOI 10.1111/aogs.12319
   Jones CL, 2018, AM J OBSTET GYNECOL, V219, DOI 10.1016/j.ajog.2018.09.029
   Kalogera E, 2013, OBSTET GYNECOL, V122, P319, DOI 10.1097/AOG.0b013e31829aa780
   Kidd EA, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004203.pub3
   Leminen A, 2000, EUR J OBSTET GYN R B, V93, P193, DOI 10.1016/S0301-2115(00)00273-6
   Liu H, 2019, BEST PRAC RES-CL ANA, V33, P487, DOI 10.1016/j.bpa.2019.07.007
   Ljungqvist O, 2017, J SURG ONCOL, V116, P608, DOI 10.1002/jso.24820
   Ljungqvist O, 2017, JAMA SURG, V152, P292, DOI 10.1001/jamasurg.2016.4952
   Long JB, 2019, J MINIM INVAS GYN, V26, P198, DOI 10.1016/j.jmig.2018.07.018
   Lyman GH, 2013, J CLIN ONCOL, V31, P2189, DOI 10.1200/JCO.2013.49.1118
   Martinez-Urtaza J, 2016, SPRINGERPLUS, V5, DOI 10.1186/s40064-016-1728-1
   Mert I, 2019, GYNECOL ONCOL, V154, P280, DOI 10.1016/j.ygyno.2019.06.008
   Meyer LA, 2018, OBSTET GYNECOL, V132, P281, DOI 10.1097/AOG.0000000000002735
   Miller TE, 2015, CAN J ANESTH, V62, P158, DOI 10.1007/s12630-014-0266-y
   Morelli M, 2013, INT J GYNECOL CANCER, V23, P1490, DOI 10.1097/IGC.0b013e3182a50517
   Morrill MY, 2013, INT J GYNECOL OBSTET, V120, P10, DOI 10.1016/j.ijgo.2012.06.023
   Mortenson MM, 2008, WORLD J SURG ONCOL, V6, DOI 10.1186/1477-7819-6-63
   Mueller MG, 2014, AM J OBSTET GYNECOL, V211, DOI 10.1016/j.ajog.2014.07.031
   Myers EM, 2017, INT UROGYNECOL J, V28, P1567, DOI 10.1007/s00192-017-3310-y
   Myles PS, 2014, LANCET, V384, P1446, DOI 10.1016/S0140-6736(14)60893-X
   Narducci F, 2012, EUR J OBSTET GYN R B, V161, P199, DOI 10.1016/j.ejogrb.2011.12.016
   Nelson G, 2016, GYNECOL ONCOL, V140, P323, DOI 10.1016/j.ygyno.2015.12.019
   Nelson G, 2016, GYNECOL ONCOL, V140, P313, DOI 10.1016/j.ygyno.2015.11.015
   Nelson G, 2019, INT J GYNECOL CANCER, V29, P651, DOI 10.1136/ijgc-2019-000356
   Newman JP, 2000, DERMATOL SURG, V26, P562, DOI 10.1046/j.1524-4725.2000.99071.x
   Nygren J, 2015, CURR OPIN ANESTHESIO, V28, P364, DOI 10.1097/ACO.0000000000000192
   O'Neal MG, 2003, AM J OBSTET GYNECOL, V189, P1539, DOI 10.1016/j.ajog.2003.10.691
   Ong CKS, 2010, ANESTH ANALG, V110, P1170, DOI 10.1213/ANE.0b013e3181cf9281
   Phipps S, 2006, COCHRANE DB SYST REV, V2
   Piovano Elisa, 2011, Gynecol Oncol Case Rep, V1, P17, DOI 10.1016/j.gynor.2011.09.002
   Pontre J, 2018, INT J GYNECOL CANCER, V28, P183, DOI 10.1097/IGC.0000000000001146
   Punjasawadwong Y, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003843.pub3
   Rahn DD, 2015, INT UROGYNECOL J, V26, P3, DOI 10.1007/s00192-014-2554-z
   Rajan P, 2017, BMC WOMENS HEALTH, V17, DOI 10.1186/s12905-017-0431-x
   REEDY MB, 1994, GYNECOL ONCOL, V53, P13, DOI 10.1006/gyno.1994.1079
   Riebe E, 2010, INT J GYNECOL CANCER, V20, P179, DOI 10.1111/IGC.0b013e3181c13343
   Rollins KE, 2018, WORLD J GASTROENTERO, V24, P519, DOI 10.3748/wjg.v24.i4.519
   Sassani JC, 2020, INT UROGYNECOL J, V31, P1305, DOI 10.1007/s00192-019-04120-7
   Schimp VL, 2004, GYNECOL ONCOL, V92, P586, DOI 10.1016/j.ygyno.2003.10.055
   Schimpf MO, 2012, FEMALE PELVIC MED RE, V18, P281, DOI 10.1097/SPV.0b013e31826446ba
   Shepherd JP, 2014, INT UROGYNECOL J, V25, P227, DOI 10.1007/s00192-013-2180-1
   Shvartsman HS, 2003, OBSTET GYNECOL, V102, P1163, DOI 10.1016/S0029-7844(03)00716-6
   Spiess PE, 2009, WORLD J UROL, V27, P205, DOI 10.1007/s00345-008-0324-6
   Stanirowski PJ, 2015, ARCH GYNECOL OBSTET, V292, P757, DOI 10.1007/s00404-015-3709-y
   SUMMITT RL, 1994, AM J OBSTET GYNECOL, V170, P1815
   Sun MJ, 2004, INT UROGYNECOL J, V15, P203, DOI 10.1007/s00192-004-1139-7
   Sun ZX, 2016, MENOPAUSE, V23, P740, DOI 10.1097/GME.0000000000000614
   Tanner J, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004122.pub4
   Tauber R, 2013, J PLAST RECONSTR AES, V66, P390, DOI 10.1016/j.bjps.2012.09.030
   Thiagamoorthy G, 2014, INT UROGYNECOL J, V25, P585, DOI 10.1007/s00192-013-2264-y
   Tranoulis A, 2018, INT J GYNECOL CANCER, V28, P1232, DOI 10.1097/IGC.0000000000001283
   Trowbridge ER, 2018, INT UROGYNECOL J, V29, P3, DOI 10.1007/s00192-017-3442-0
   Walker KF, 2011, INT J GYNECOL CANCER, V21, P1495, DOI 10.1097/IGC.0b013e318228f314
   Weingarten TN, 2015, REGION ANESTH PAIN M, V40, P330, DOI 10.1097/AAP.0000000000000257
   Westermann LB, 2016, FEMALE PELVIC MED RE, V22, P111, DOI 10.1097/SPV.0000000000000238
   Wigmore TJ, 2016, ANESTHESIOLOGY, V124, P69, DOI 10.1097/ALN.0000000000000936
   Wills A, 2013, GYNECOL ONCOL, V131, P467, DOI 10.1016/j.ygyno.2013.07.082
   Ye S, 2015, MEDICINE, V94, DOI 10.1097/MD.0000000000002316
NR 99
TC 54
Z9 65
U1 0
U2 15
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0002-9378
EI 1097-6868
J9 AM J OBSTET GYNECOL
JI Am. J. Obstet. Gynecol.
PD OCT
PY 2020
VL 223
IS 4
BP 475
EP 485
DI 10.1016/j.ajog.2020.07.039
PG 11
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA OD7LS
UT WOS:000580031200005
PM 32717257
DA 2026-07-24
ER

PT J
AU Robbins, JM
   Dillon, J
AF Robbins, Jeffrey M.
   Dillon, Jeremiah
TI Evidence-Based Approach to Advanced Wound Care Products
SO JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; HYPERBARIC-OXYGEN;
   GROWTH-FACTOR; TOPICAL OXYGEN; LEG ULCERS; SILVER; SKIN; SURVIVAL;
   INTERVENTIONS
AB There is increasing pressure from industry to use advanced wound care products and technologies. Many are very expensive but promise to reduce overall costs associated with wound care. Compelling anecdotal evidence is provided that inevitably shows wounds that failed all other treatments but responded positively to the subject product. Evidence-based medicine is the standard by which physician-scientists must make their clinical care decisions. In an attempt to provide policy makers with the most current evidence on advanced wound care products, the Department of Veteran Affairs conducted an Evidence-based Synthesis Program review of advanced wound care products. This paper suggests how to take this information and apply it to policy to drive evidence-based care to improve outcomes and fiduciary responsibility.
C1 [Robbins, Jeffrey M.] Louis Stokes Cleveland Vet Affairs Med Ctr, Podiatry Sect, Podiatry Serv, Vet Affairs Cent Off, Cleveland, OH 44107 USA.
   [Dillon, Jeremiah] Louis Stokes Cleveland Vet Affairs Med Ctr, Cleveland, OH 44107 USA.
C3 University System of Ohio; Case Western Reserve University; US
   Department of Veterans Affairs; Veterans Health Administration (VHA);
   Louis Stokes Cleveland Veterans Affairs Medical Center; University
   System of Ohio; Case Western Reserve University; US Department of
   Veterans Affairs; Veterans Health Administration (VHA); Louis Stokes
   Cleveland Veterans Affairs Medical Center
RP Robbins, JM (通讯作者)，Louis Stokes Cleveland Vet Affairs Med Ctr, Podiatry Sect, VACO, Podiatry Serv, 10701 E Blvd, Cleveland, OH 44107 USA.
EM Jeffrey.robbins@va.gov
CR Allen DB, 1997, ARCH SURG-CHICAGO, V132, P991
   [Anonymous], 1999, DIABETES CARE, V22, P1354, DOI DOI 10.2337/DIACARE.22.8.1354
   Armstrong DG, 2013, DIABETES CARE, V36, P1815, DOI 10.2337/dc12-2285
   Armstrong DG, 2001, DIABETES CARE, V24, P1019, DOI 10.2337/diacare.24.6.1019
   Atiyeh BS, 2007, BURNS, V33, P139, DOI 10.1016/j.burns.2006.06.010
   AUBOCK J, 1988, TRANSPLANTATION, V45, P730, DOI 10.1097/00007890-198804000-00013
   Boulton AJM, 2004, NEW ENGL J MED, V351, P48, DOI 10.1056/NEJMcp032966
   Bowler PG, 2001, CLIN MICROBIOL REV, V14, P244, DOI 10.1128/CMR.14.2.244-269.2001
   BURR H. S., 1940, YALE JOUR BIOL AND MED, V12, P483
   BURT AM, 1989, BMJ-BRIT MED J, V298, P915, DOI 10.1136/bmj.298.6678.915
   Cavanagh PR, 2005, LANCET, V366, P1725, DOI 10.1016/S0140-6736(05)67699-4
   Comerota AJ, 2011, J VASC SURG, V53, P1121, DOI 10.1016/j.jvs.2010.08.059
   Cullen B, 2002, WOUND REPAIR REGEN, V10, P16, DOI 10.1046/j.1524-475X.2002.10703.x
   DELUCA M, 1992, ARCH DERMATOL, V128, P633, DOI 10.1001/archderm.128.5.633
   Duinslaeger L, 1996, PLAST RECONSTR SURG, V98, P110, DOI 10.1097/00006534-199607000-00018
   Ehrenreich M, 2006, TISSUE ENG, V12, P2407, DOI 10.1089/ten.2006.12.2407
   Fang KS, 1999, J CELL SCI, V112, P1967
   Feldmeier JJ, 2005, UNDERSEA HYPERBAR M, V32, P157
   FOULDS IS, 1983, BRIT J DERMATOL, V109, P515, DOI 10.1111/j.1365-2133.1983.tb07673.x
   Fries RB, 2005, MUTAT RES-FUND MOL M, V579, P172, DOI 10.1016/j.mrfmmm.2005.02.023
   Game FL, 2012, DIABETES-METAB RES, V28, P119, DOI 10.1002/dmrr.2246
   Gill AL, 2004, QJM-INT J MED, V97, P385, DOI 10.1093/qjmed/hch074
   Gordillo GM, 2008, CLIN EXP PHARMACOL P, V35, P957, DOI 10.1111/j.1440-1681.2008.04934.x
   Gordillo GM, 2003, AM J SURG, V186, P259, DOI 10.1016/S0002-9610(03)00211-3
   Gottrup F, 2012, DIABETES-METAB RES, V28, P64, DOI 10.1002/dmrr.2242
   Greer N., 2012, ADV WOUND CARE THERA
   Greif R, 2000, NEW ENGL J MED, V342, P161, DOI 10.1056/NEJM200001203420303
   HEFTON JM, 1986, J AM ACAD DERMATOL, V14, P399, DOI 10.1016/S0190-9622(86)70048-0
   Hinchliffe RJ, 2008, DIABETES-METAB RES, V24, pS119, DOI 10.1002/dmrr.825
   Hodde J P, 1996, Tissue Eng, V2, P209, DOI 10.1089/ten.1996.2.209
   Hodde JP, 2007, AM J CLIN DERMATOL, V8, P61, DOI 10.2165/00128071-200708020-00001
   Hodde JP, 2001, WOUNDS, V13, P195
   Hodde JP., 2005, J WOUND CARE, V14, P23, DOI DOI 10.12968/jowc.2005.14.1.26721
   Hollinger MA, 1996, CRIT REV TOXICOL, V26, P255, DOI 10.3109/10408449609012524
   Hopf HW, 2005, WOUND REPAIR REGEN, V13, P558, DOI 10.1111/j.1524-475X.2005.00078.x
   Hopf HW, 1997, ARCH SURG-CHICAGO, V132, P997
   Illingworth C. M., 1980, Clinical Physics and Physiological Measurement, V1, P87, DOI 10.1088/0143-0815/1/1/007
   *INT WORK GROUP DI, 2003, INT CONS DIAB FOOT
   Ip M, 2006, J MED MICROBIOL, V55, P59, DOI 10.1099/jmm.0.46124-0
   JENSEN JA, 1986, LAB INVEST, V54, P574
   JONSSON K, 1991, ANN SURG, V214, P605, DOI 10.1097/00000658-199111000-00011
   KAAWACH WF, 1991, BRIT J PLAST SURG, V44, P321, DOI 10.1016/0007-1226(91)90142-7
   Klasen HJ, 2000, BURNS, V26, P117, DOI 10.1016/S0305-4179(99)00108-4
   KNIGHTON DR, 1983, SCIENCE, V221, P1283, DOI 10.1126/science.6612342
   KNIGHTON DR, 1986, ARCH SURG-CHICAGO, V121, P191
   Kurd SK, 2009, WOUND REPAIR REGEN, V17, P318, DOI 10.1111/j.1524-475X.2009.00487.x
   Lacci Kathleen M., 2010, Yale Journal of Biology and Medicine, V83, P1
   Lee Raphael C., 1993, Journal of Burn Care and Rehabilitation, V14, P319, DOI 10.1097/00004630-199305000-00003
   LEIGH IM, 1987, BRIT J DERMATOL, V117, P591, DOI 10.1111/j.1365-2133.1987.tb07491.x
   LEIGH IM, 1986, CLIN EXP DERMATOL, V11, P650, DOI 10.1111/j.1365-2230.1986.tb00526.x
   Limova M, 2010, SURG CLIN N AM, V90, P1237, DOI 10.1016/j.suc.2010.08.004
   Lipsky BA, 2012, CLIN INFECT DIS, V54, P1679, DOI [10.1093/cid/cis460, 10.1093/cid/cis346]
   Mansbridge J, 1998, TISSUE ENG, V4, P403, DOI 10.1089/ten.1998.4.403
   Mansbridge JN, 1999, DIABETES OBES METAB, V1, P265, DOI 10.1046/j.1463-1326.1999.00032.x
   McDevitt CA, 2003, J BIOMED MATER RES A, V67A, P637, DOI 10.1002/jbm.a.10144
   MCKAY IA, 1991, BRIT J DERMATOL, V124, P513, DOI 10.1111/j.1365-2133.1991.tb04942.x
   McPherson TB, 1998, TISSUE ENG, V4, P75, DOI 10.1089/ten.1998.4.75
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   MUELLER MJ, 1989, DIABETES CARE, V12, P384, DOI 10.2337/diacare.12.6.384
   Naughton G, 1997, ARTIF ORGANS, V21, P1203
   Nuccitelli R, 2003, CURR TOP DEV BIOL, V58, P1, DOI 10.1016/S0070-2153(03)58001-2
   OLENIUS M, 1993, PLAST RECONSTR SURG, V91, P213, DOI 10.1097/00006534-199302000-00001
   Phillips T, 2002, ARCH DERMATOL, V138, P1079, DOI 10.1001/archderm.138.8.1079
   PIERCE GF, 1991, J CELL BIOCHEM, V45, P319, DOI 10.1002/jcb.240450403
   Plafki C, 2000, AVIAT SPACE ENVIR MD, V71, P119
   Poon VKM, 2004, BURNS, V30, P140, DOI 10.1016/j.burns.2003.09.030
   Rollins MD, 2006, UNDERSEA HYPERBAR M, V33, P17
   Sai P, 2000, BURNS, V26, P54
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Scott GF, 2005, WOUND REPAIR REGEN, V13, pA4
   Sheehan P, 2006, PLAST RECONSTR SURG, V117, p239S, DOI 10.1097/01.prs.0000222891.74489.33
   Sheffield P.J., 1985, Hyperb Oxyg Rev, V6, P18
   Song B, 2002, P NATL ACAD SCI USA, V99, P13577, DOI 10.1073/pnas.202235299
   Thackham JA, 2008, WOUND REPAIR REGEN, V16, P321, DOI 10.1111/j.1524-475X.2008.00372.x
   Thom SR, 2009, J APPL PHYSIOL, V106, P988, DOI 10.1152/japplphysiol.91004.2008
   Tompach PC, 1997, INT J ORAL MAX SURG, V26, P82, DOI 10.1016/S0901-5027(05)80632-0
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Wright JG, 2003, J BONE JOINT SURG AM, V85A, P1, DOI 10.2106/00004623-200301000-00001
   Zhao M, 2006, NATURE, V442, P457, DOI 10.1038/nature04925
NR 79
TC 6
Z9 8
U1 0
U2 4
PU AMER PODIATRIC MED ASSOC
PI BETHESDA
PA 9312 OLD GEORGETOWN ROAD, BETHESDA, MD 20814-1621 USA
SN 8750-7315
EI 1930-8264
J9 J AM PODIAT MED ASSN
JI J. Am. Podiatr. Med. Assoc.
PD SEP-OCT
PY 2015
VL 105
IS 5
BP 456
EP 467
DI 10.7547/14-089
PG 12
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA DA3DF
UT WOS:000367675700014
PM 26429618
DA 2026-07-24
ER

PT J
AU Schulz, D
   Mohor, GS
   Solovan, C
AF Schulz, Dietmar
   Mohor, Georgiana Simona
   Solovan, Caius
TI Unusual foreign body in the sigmoid colon, chronic alcohol abuse, and
   Fournier gangrene: a case report
SO CLINICAL INTERVENTIONS IN AGING
LA English
DT Article
DE pancreatic stent; wound debridement; vacuum-assisted closure;
   transplanted skin; necrotizing infection
AB Fournier gangrene (FG) is an infectious condition with fulminant evolution and is sometimes life-threatening. Here, we present the case of an immunocompromised 59-year-old male with surgical history of a pancreatic pseudocyst stented endoscopically. After unrecognized stent migration in the sigmoid without colonic perforation, he developed severe necrosis of the scrotum and perineum, which spontaneously perforated, presenting a smell suggesting moist gangrene. FG that has spread to the male genital organs presents therapeutic challenges. The purpose of our study is to present this case, typical for FG, with an educational aim both for the internal and surgical specialties, and the goal of further multidisciplinary collaboration for the optimal management of the patient with personalized treatment.
C1 [Schulz, Dietmar] Sana Kliniken Leipziger Land, Urol Klin, Leipzig, Germany.
   [Mohor, Georgiana Simona; Solovan, Caius] Univ Clin Dermatol & Venereol, Timisoara, Romania.
   [Solovan, Caius] Victor Babes Univ Med & Pharm, Dept Dermatol, Timisoara, Romania.
C3 Victor Babes University of Medicine & Pharmacy, Timisoara
RP Mohor, GS (通讯作者)，Univ Clin Dermatol & Venereol, Marasesti Nr 5, Timisoara, Romania.
EM simona.mohor@gmx.de
CR Ahmadnia H, 2009, URO TODAY INT J, V2
   [Anonymous], 1883, SEMIN MED
   [Anonymous], COCHRANE DATABASE SY, DOI DOI 10.1002/14651858.CD007937.PUB2
   Capelli-Schellpfeffer M, 1999, J UROLOGY, V162, P647, DOI 10.1097/00005392-199909010-00002
   Ferreira PC, 2007, PLAST RECONSTR SURG, V119, P175, DOI 10.1097/01.prs.0000244925.80290.57
   Grabe M., 2011, Guidelines on urological infections
   Kujath P, 2002, DEUT MED WOCHENSCHR, V127, P2508, DOI 10.1055/s-2002-35644
   Marsman J W, 1996, Australas Radiol, V40, P80
   Morpurgo E, 2002, SURG CLIN N AM, V82, P1213, DOI 10.1016/S0039-6109(02)00058-0
   Nakatani H, 2011, J MED INVESTIG, V58, P255, DOI 10.2152/jmi.58.255
   Pais Jr VM, MEDSCAPE
   Papachristodoulou AJ, 1997, LANGENBECK ARCH CHIR, V382, P15, DOI 10.1007/BF02539302
   Pastore Antonio Luigi, 2013, J Med Case Rep, V7, P1, DOI 10.1186/1752-1947-7-1
   Pour SM, 2011, J WOUND OSTOMY CONT, V38, P449, DOI 10.1097/WON.0b013e31821e43f1
   Wróblewska M, 2014, POL J MICROBIOL, V63, P267
   Yilmazlar T, 2014, ULUS TRAVMA ACIL CER, V20, P333, DOI 10.5505/tjtes.2014.06870
NR 16
TC 4
Z9 4
U1 0
U2 1
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
EI 1178-1998
J9 CLIN INTERV AGING
JI Clin. Interv. Aging
PY 2015
VL 10
BP 673
EP 677
DI 10.2147/CIA.S79609
PG 5
WC Geriatrics & Gerontology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Geriatrics & Gerontology
GA CE7IY
UT WOS:000352013800001
PM 25878494
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Amsellem, P
AF Amsellem, Pierre
TI Complications of Reconstructive Surgery in Companion Animals
SO VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
LA English
DT Article
DE Complications; Skin Reconstructive surgery; Maxillectomy;
   Hemipelvectomy; Radiation therapy
ID AXIAL PATTERN FLAP; VACUUM-ASSISTED CLOSURE; SKIN-GRAFTS; ORONASAL
   FISTULA; CLINICAL-EVALUATION; RADIATION-THERAPY; BLOOD-FLOW; MOUSE SKIN;
   10 DOGS; CATS
AB Factors that affect wound healing include the general health of the patient, nutritional status, and wound factors. Treatments such as corticosteroids, chemotherapy, or radiation are also common causes of delayed healing. Multimodal cancer treatment has become more common and the veterinary surgeon may be required to perform reconstructive procedures on an animal that has received or will receive chemotherapy and/or radiation treatments. Complications of reconstructive cutaneous procedures include seroma, hematoma formation, infection, wound dehiscence, distal tip necrosis of skin flaps, paresthesia, and free skin graft failure. Procedures such as maxillectomy or hemipelvectomy also have complications. Knowledge of common complications can facilitate client education and even allow the surgeon to avoid these complications.
C1 Wey Referrals, Amer Coll Vet Surg, Woking GU21 5BP, Surrey, England.
RP Amsellem, P (通讯作者)，Wey Referrals, Amer Coll Vet Surg, 125-129 Chertsey, Woking GU21 5BP, Surrey, England.
EM pierreamsellem@hotmail.com
CR Aper R, 2003, VET SURG, V32, P378, DOI 10.1053/jvet.2003.50043
   Aper RL, 2005, J AM ANIM HOSP ASSOC, V41, P185, DOI 10.5326/0410185
   BATCHELOR AGG, 1984, BRIT J PLAST SURG, V37, P358, DOI 10.1016/0007-1226(84)90079-1
   Ben-Amotz R, 2007, VET SURG, V36, P684, DOI 10.1111/j.1532-950X.2007.00321.x
   Bohling MW, 2004, VET SURG, V33, P579, DOI 10.1111/j.1532-950X.2004.04081.x
   Bryant KJ, 2003, VET SURG, V32, P113, DOI 10.1053/jvet.2003.50018
   BUCKNALL TE, 1980, BRIT J SURG, V67, P851, DOI 10.1002/bjs.1800671205
   Clarke BS, 2010, J SMALL ANIM PRACT, V51, P495, DOI 10.1111/j.1748-5827.2010.00969.x
   CORNELL K, 1995, VET CLIN N AM-SMALL, V25, P111, DOI 10.1016/S0195-5616(95)50008-7
   DAWSON I, 1989, BRIT J SURG, V76, P311, DOI 10.1002/bjs.1800760329
   de Souza HJM, 2005, J FELINE MED SURG, V7, P129, DOI [10.1016/j.jfms.2004.02.005, 10.1016/j.jfms.2004.06.003]
   DERNELL W, 1995, SURG MANAGEMENT RAD
   DERNELL WS, 1995, COMP CONT EDUC PRACT, V17, P181
   Doyle JW, 1996, PLAST RECONSTR SURG, V98, P129, DOI 10.1097/00006534-199607000-00020
   Duncan B, 2003, J AM ANIM HOSP ASSOC, V39, P294
   EHRLICH HP, 1968, ANN SURG, V167, P324, DOI 10.1097/00000658-196803000-00004
   GORODETSKY R, 1988, RADIAT RES, V116, P135, DOI 10.2307/3577484
   GORODETSKY R, 1990, INT J RADIAT ONCOL, V18, P1077, DOI 10.1016/0360-3016(90)90443-N
   Guille AE, 2007, JAVMA-J AM VET MED A, V230, P1669, DOI 10.2460/javma.230.11.1669
   HILLELSON RL, 1980, PLAST RECONSTR SURG, V66, P528, DOI 10.1097/00006534-198010000-00004
   HOLDER KN, 2010, PATHOLOGY CASE REV, V15, P148, DOI DOI 10.1097/PCR.0B013E3181F66188
   Huttunen M, 2001, EXP DERMATOL, V10, P184, DOI 10.1034/j.1600-0625.2001.010003184.x
   JOHNSTON DE, 1990, VET CLIN N AM-SMALL, V20, P67, DOI 10.1016/S0195-5616(90)50004-2
   KARAKOUSIS CP, 1989, AM J SURG, V158, P404, DOI 10.1016/0002-9610(89)90273-0
   KENYON AJ, 1983, AM J VET RES, V44, P2164
   KERRIGAN CL, 1983, PLAST RECONSTR SURG, V71, P519, DOI 10.1097/00006534-198304000-00012
   KERWIN SC, 1993, VET SURG, V22, P31, DOI 10.1111/j.1532-950X.1993.tb00365.x
   Kramer A, 2008, VET SURG, V37, P413, DOI 10.1111/j.1532-950X.2008.00405.x
   KRAYBILL WG, 1992, J SURG ONCOL, V51, P38, DOI 10.1002/jso.2930510111
   Lawrence CJ, 1996, ANESTH ANALG, V83, P1160, DOI 10.1097/00000539-199612000-00005
   Liptak J, 2009, COMPEND CONTIN ED VE, V31, pE1
   Matthiesen D T, 1990, Probl Vet Med, V2, P248
   MCCAW DL, 1989, SEMIN VET MED SURG, V4, P281
   MYERS MB, 1964, SURGERY, V56, P945
   NATHANSON SE, 1975, ARCH OTOLARYNGOL, V101, P354
   NAYMAN J, 1966, ANN SURG, V164, P227, DOI 10.1097/00000658-196608000-00007
   PAVLETIC MM, 1982, VET SURG, V11, P18, DOI 10.1111/j.1532-950X.1982.tb00659.x
   PAVLETIC MM, 2010, ATLAS SMALL ANIMAL W, P128
   PAVLETIC MM, 2002, TXB SMALL ANIMAL SUR, V1, P292
   Pavletic MM., 2010, Atlas of Small Animal Wound Management and Reconstructive Surgery, V3rd ed., P242
   PEREZTAMAYO R, 1953, AM J PATHOL, V29, P233
   POPE ER, 1986, VET SURG, V15, P65, DOI 10.1111/j.1532-950X.1986.tb00178.x
   Porter KA, 1998, AM J SURG, V176, P8, DOI 10.1016/S0002-9610(98)00093-2
   Reetz JA, 2006, JAVMA-J AM VET MED A, V228, P1361, DOI 10.2460/javma.228.9.1361
   Remedies A., 1999, BSAVA Manual of canine and feline wound management and reconstruction, P137
   RUDOLPH R, 1982, PLAST RECONSTR SURG, V70, P179, DOI 10.1097/00006534-198208000-00009
   SALISBURY SK, 1985, VET SURG, V14, P265, DOI 10.1111/j.1532-950X.1985.tb00882.x
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   SCHWARZ PD, 1991, J AM ANIM HOSP ASSOC, V27, P617
   Séguin B, 2005, VET SURG, V34, P214, DOI [10.1111/j.1532-950x.2005.00033.x, 10.1111/j.1532-950X.2005.00033.x]
   Séguin B, 2001, J AM VET MED ASSOC, V218, P1120, DOI 10.2460/javma.2001.218.1120
   Shahar R, 1999, J SMALL ANIM PRACT, V40, P378, DOI 10.1111/j.1748-5827.1999.tb03104.x
   Siegfried R, 2004, SCHWEIZ ARCH TIERH, V146, P277, DOI 10.1024/0036-7281.146.6.277
   Sivacolundhu RK, 2007, CLIN TECH SMALL AN P, V22, P61, DOI 10.1053/j.ctsap.2007.03.005
   Smith MM, 2001, J VET DENT, V18, P127, DOI 10.1177/089875640101800303
   Smith MM, 2000, CLIN TECH SMALL AN P, V15, P243, DOI 10.1053/svms.2000.21398
   STRAW RC, 1992, VET SURG, V21, P183, DOI 10.1111/j.1532-950X.1992.tb00043.x
   SWAIM SF, 2002, TXB SMALL ANIMAL SUR, V1, P321
   SWAIM SF, 1997, SMALL ANIMAL WOUND M
   Swaim SF, 1980, SURG TRAUMATIZED SKI
   Thamm DH, 2006, WITHROW MACEWENS SMA, V4th, P402
   Tibbs MK, 1997, RADIOTHER ONCOL, V42, P99, DOI 10.1016/S0167-8140(96)01880-4
   TREVOR PB, 1992, J AM VET MED ASSOC, V201, P608
   VASSEUR PB, 1988, VET SURG, V17, P60, DOI 10.1111/j.1532-950X.1988.tb00278.x
   WARIS T, 1989, BRIT J PLAST SURG, V42, P576, DOI 10.1016/0007-1226(89)90049-0
   WARIS T, 1978, SCAND J PLAST RECONS, V12, P95, DOI 10.3109/02844317809012979
   Weiss-Becker C, 1998, SCAND J PLAST RECONS, V32, P157, DOI 10.1080/02844319850158778
   White R., 1999, Manual of canine and feline wound management and reconstruction, V1st, P83
   WHITLOCK MR, 1983, BRIT J PLAST SURG, V36, P240, DOI 10.1016/0007-1226(83)90100-5
NR 69
TC 38
Z9 39
U1 1
U2 33
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0195-5616
EI 1878-1306
J9 VET CLIN N AM-SMALL
JI Vet. Clin. N. Am.-Small Anim. Pract.
PD SEP
PY 2011
VL 41
IS 5
BP 995
EP +
DI 10.1016/j.cvsm.2011.05.005
PG 13
WC Veterinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Veterinary Sciences
GA 829RK
UT WOS:000295601800010
PM 21889697
DA 2026-07-24
ER

PT J
AU Shi, JY
   Gao, Y
   Tian, JH
   Li, J
   Xu, JG
   Mei, F
   Li, Z
AF Shi, Jiyuan
   Gao, Ya
   Tian, Jinhui
   Li, Jiang
   Xu, Jianguo
   Mei, Fan
   Li, Zheng
TI Negative pressure wound therapy for treating pressure ulcers
SO COCHRANE DATABASE OF SYSTEMATIC REVIEWS
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; RANDOMIZED CONTROLLED-TRIAL;
   SPINAL-CORD-INJURY; RISK-FACTORS; COST-EFFECTIVENESS; BACTERIAL LOAD;
   CLINICAL-TRIAL; PREVALENCE; CARE; MANAGEMENT
AB Background
   Pressure ulcers, also known as bedsores, pressure sores, or pressure injuries, are localised damage to the skin and underlying soft tissue, usually caused by intense or long-term pressure, shear, or friction. Negative pressure wound therapy (NPWT) has been widely used in the treatment of pressure ulcers, but its effect needs to be further clarified. This is an update of a Cochrane Review first published in 2015.
   Objectives
   To evaluate the effectiveness of NPWT for treating adult with pressure ulcers in any care setting.
   Search methods
   On 13 January 2022, we searched the Cochrane Wounds Specialised Register; the Cochrane Central Register of Controlled Trials (CENTRAL); Ovid MEDLINE (including In-Process & Other Non-Indexed Citations); Ovid Embase, and EBSCO CINAHL Plus. We also searched ClinicalTrials.gov and the WHO ICTRP Search Portal for ongoing and unpublished studies and scanned reference lists of relevant included studies as well as reviews, meta-analyses, and health technology reports to identify additional studies. There were no restrictions with respect to language, date of publication, or study setting.
   Selection criteria
   We included published and unpublished randomised controlled trials (RCTs) comparing the effects of NPWT with alternative treatments or different types of NPWT in the treatment of adults with pressure ulcers (stage II or above).
   Data collection and analysis
   Two review authors independently conducted study selection, data extraction, risk of bias assessment using the Cochrane risk of bias tool, and the certainty of the evidence assessment using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) methodology. Any disagreement was resolved by discussion with a third review author.
   Main results
   This review included eight RCTs with a total of 327 randomised participants. Six of the eight included studies were deemed to be at a high risk of bias in one or more risk of bias domains, and evidence for all outcomes of interest was deemed to be of very low certainty. Most studies had small sample sizes (range: 12 to 96, median: 37 participants).
   Five studies compared NPWT with dressings, but only one study reported usable primary outcome data (complete wound healing and adverse events). This study had only 12 participants and there were very few events; only one participant was healed in the study (risk ratio RR) 3.00, 95% confidence interval (CI) 0.15 to 61.74, very low-certainly evidence). There was no evidence of a difference in the number of participants with adverse events in the NPWT group and the dressing group, but the evidence for this outcome was also assessed as very low certainty (RR 1.25, 95% CI 0.64 to 2.44, very low-certainty evidence). Changes in ulcer size, pressure ulcer severity, cost, and pressure ulcer scale for healing (PUSH) sores were also reported, but we were unable to draw conclusions due to the low certainly of the evidence.
   One study compared NPWT with a series of gel treatments, but this study provided no usable data. Another study compared NPWT with 'moist wound healing', which did not report primary outcome data. Changes in ulcer size and cost were reported in this study, but we assessed the evidence as being of very low certainty; One study compared NPWT combined with internet-plus home care with standard care, but no primary outcome data were reported. Changes in ulcer size, pain, and dressing change times were reported, but we also assessed the evidence as being of very low certainty.
   None of the included studies reported time to complete healing, health-related quality of life, wound infection, or wound recurrence.
   Authors' conclusions The efficacy, safety, and acceptability of NPWT in treating pressure ulcers compared to usual care are uncertain due to the lack of key data on complete wound healing, adverse events, time to complete healing, and cost-effectiveness.
   Compared with usual care, using NPWT may speed up the reduction of pressure ulcer size and severity of pressure ulcer, reduce pain, and dressing change times. Still, trials were small, poorly described, had short follow-up times, and with a high risk of bias; any conclusions drawn from the current evidence should be interpreted with considerable caution. In the future, high-quality research with large sample sizes and low risk of bias is still needed to further verify the eJicacy, safety, and cost-eJectiveness of NPWT in the treatment of pressure ulcers. Future researchers need to recognise the importance of complete and accurate reporting of clinically important outcomes such as the complete healing rate, healing time, and adverse events.
C1 [Shi, Jiyuan; Li, Zheng] Chinese Acad Med Sci & Peking Union Med Coll, Sch Nursing, Beijing, Peoples R China.
   [Gao, Ya; Tian, Jinhui; Xu, Jianguo] Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, Lanzhou, Peoples R China.
   [Li, Jiang] Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Natl Canc Clin Med Res Ctr, Canc Hosp, Beijing, Peoples R China.
   [Mei, Fan] Sichuan Univ, West China Hosp, Chinese Evidence Based Med Ctr, Chengdu, Peoples R China.
   [Mei, Fan] Sichuan Univ, West China Hosp, Cochrane China Ctr, Chengdu, Peoples R China.
C3 Chinese Academy of Medical Sciences - Peking Union Medical College;
   Peking Union Medical College; Lanzhou University; Chinese Academy of
   Medical Sciences - Peking Union Medical College; Peking Union Medical
   College; Cancer Institute & Hospital - CAMS; Sichuan University; Sichuan
   University
RP Li, Z (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Sch Nursing, Beijing, Peoples R China.
EM zhengli@pumc.edu.cn
RI Li, Zheng/OHT-0437-2025; Shi, Jiyuan/ACB-6953-2022; Gao,
   Ya/HGA-2705-2022
OI Shi, Jiyuan/0000-0001-5099-9439; Gao, Ya/0000-0002-9280-4457
CR Ali Z, 2017, J ORTHOP SURG RES, V12, DOI 10.1186/s13018-017-0558-3
   Ali Z, 2015, J ORTHOP SURG RES, V10, DOI 10.1186/s13018-015-0314-5
   Alipoor E, 2021, CLIN NUTR, V40, P5089, DOI 10.1016/j.clnu.2021.08.006
   Allman RM, 1997, CLIN GERIATR MED, V13, P421
   Andrianasolo J, 2018, BMC INFECT DIS, V18, DOI 10.1186/s12879-018-3076-y
   [Anonymous], 2016, NPUAP Pressure Injury Stages
   [Anonymous], 2020, Review Manager (RevMan 5) [computer program]
   [Anonymous], Science behind wound therapy
   [Anonymous], 2004, 2 WORLD UN WOUND HEA
   [Anonymous], 2019, The International Guideline
   Ashby RL, 2012, TRIALS, V13, DOI 10.1186/1745-6215-13-119
   Baek W, 2020, PHARMACEUTICS, V12, DOI 10.3390/pharmaceutics12090813
   Bergstrom N, 1998, NURS RES, V47, P261, DOI 10.1097/00006199-199809000-00005
   BERLOWITZ DR, 1989, J AM GERIATR SOC, V37, P1043, DOI 10.1111/j.1532-5415.1989.tb06918.x
   Berlowitz DR, 1997, J AM GERIATR SOC, V45, P30, DOI 10.1111/j.1532-5415.1997.tb00974.x
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   BRANDEIS GH, 1994, J AM GERIATR SOC, V42, P388, DOI 10.1111/j.1532-5415.1994.tb07486.x
   Chaboyer W, 2022, INT J NURS STUD, V128, DOI 10.1016/j.ijnurstu.2022.104189
   Chan B, 2013, J WOUND CARE, V22, P341, DOI 10.12968/jowc.2013.22.7.341
   Chen CS, 2018, FORMOS J SURG, V51, P223, DOI 10.4103/fjs.fjs_176_17
   Ciliberti M, 2016, WOUNDS, V28, P408
   Coleman S, 2013, INT J NURS STUD, V50, P974, DOI 10.1016/j.ijnurstu.2012.11.019
   de Laat EHEW, 2011, ANN PLAS SURG, V67, P626, DOI 10.1097/SAP.0b013e31820b3ac1
   Dealey C, 2012, J WOUND CARE, V21, P261, DOI 10.12968/jowc.2012.21.6.261
   Demarré L, 2015, INT J NURS STUD, V52, P1754, DOI 10.1016/j.ijnurstu.2015.06.006
   Donini LM, 2005, J NUTR HEALTH AGING, V9, P446
   Dumville JC, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011334.pub2
   Dwivedi MK, 2016, J WOUND CARE, V25, P199, DOI 10.12968/jowc.2016.25.4.199
   Dwivedi MK, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9327
   Dwivedi MK, 2017, J WOUND OSTOMY CONT, V44, P343, DOI 10.1097/WON.0000000000000333
   Essex HN, 2009, WOUND REPAIR REGEN, V17, P797, DOI 10.1111/j.1524-475X.2009.00544.x
   Ford CN, 2002, ANN PLAS SURG, V49, P55, DOI 10.1097/00000637-200207000-00009
   Gao Yi-bin, 2015, Zhongguo Gu Shang, V28, P150
   Gebhardt Krzysztof, 2002, Nurs Times, V98, P41
   Gefen A, 2014, OSTOMY WOUND MANAG, V60, P34
   Glanville J, 2019, HEALTH INFO LIBR J, V36, P73, DOI 10.1111/hir.12251
   Gould L, 2016, WOUND REPAIR REGEN, V24, P145, DOI 10.1111/wrr.12396
   Greer SE, 1999, Wound Repair and Regeneration, V7
   Guy Heidi, 2012, Nurs Times, V108, P20
   Hajhosseini B, 2020, ANN SURG, V271, P671, DOI 10.1097/SLA.0000000000003567
   Hampton Jane, 2015, Br J Community Nurs, VSuppl Community Wound Care, pS16, DOI [10.12968/bjcn.2015.20.sup6.s14, 10.12968/bjcn.2015.20.Sup6.S14]
   Higgins J., 2011, CHAPTER 8 ASSESSING
   Higgins J.P. T., 2022, COCHRANE HDB SYSTEMA, P2022
   Higgins J.P. T., 2011, Cochrane Handb Syst Rev Interv, DOI DOI 10.1002/9781119536604.CH8
   Higgins JPT, 2003, BMJ-BRIT MED J, V327, P557, DOI 10.1136/bmj.327.7414.557
   HU Kai-xuan, 2009, Zhonghua Shao Shang Za Zhi, V25, P249
   Joseph E, 2000, WOUNDS, V12, P60
   Kontopantelis E, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0069930
   Kontopantelis E, 2012, STAT METHODS MED RES, V21, P409, DOI 10.1177/0962280210392008
   Kumar V, 2021, VALUE HEALTH, V24, pS122, DOI 10.1016/j.jval.2021.04.593
   Labeau SO, 2021, INTENS CARE MED, V47, P160, DOI 10.1007/s00134-020-06234-9
   Langer G, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003216.pub2
   Liberati A, 2009, PLOS MED, V6, DOI 10.1371/journal.pmed.1000100
   Liu Q, 2021, CLINICS, V76, DOI 10.6061/clinics/2021/e2355
   Lyder CH, 2012, J AM GERIATR SOC, V60, P1603, DOI 10.1111/j.1532-5415.2012.04106.x
   Mari W, 2019, WOUNDS, V31, P117
   McCallon SK, 2015, WOUNDS, V27, P44
   Mody GN, 2008, OSTOMY WOUND MANAG, V54, P36
   Mohammed AH, 2020, J TISSUE VIABILITY, V29, P37, DOI 10.1016/j.jtv.2019.10.003
   Mouës CM, 2007, J PLAST RECONSTR AES, V60, P672, DOI 10.1016/j.bjps.2006.01.041
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   National Institute for Health and Clinical Excellence, 2018, 2018 surveillance of pressure ulcers: prevention and management (NICE guideline CG179)
   Nghiem S, 2022, INT J NURS STUD, V130, DOI 10.1016/j.ijnurstu.2022.104191
   Niezgoda JA, 2004, 2 WORLD UN WOUND HEA
   Papp AA, 2019, INT WOUND J, V16, P394, DOI 10.1111/iwj.13045
   Parmar MKB, 1998, STAT MED, V17, P2815, DOI 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8
   Pruksapong Chatchai, 2011, Journal of the Medical Association of Thailand, V94, P1212
   Qaseem A, 2015, ANN INTERN MED, V162, P370, DOI 10.7326/M14-1568
   Rahmanian-Schwarz A, 2012, BURNS, V38, P573, DOI 10.1016/j.burns.2011.10.010
   Rrapi R, 2021, J AM ACAD DERMATOL, V85, P462, DOI 10.1016/j.jaad.2021.03.051
   Schmitt J, 2019, J INVEST DERMATOL, V139, P1045, DOI 10.1016/j.jid.2018.11.019
   Schulz KF, 2010, J CLIN EPIDEMIOL, V63, P834, DOI [10.1136/bmj.c332, 10.1371/journal.pmed.1000251, 10.1016/j.jclinepi.2010.02.005]
   Schunemann HJ, 2022, Cochrane Handbook for systematic Reviews of Interventions version 6.5
   Smith MEB, 2013, ANN INTERN MED, V159, P39, DOI 10.7326/0003-4819-159-1-201307020-00007
   Soares MO, 2013, MED DECIS MAKING, V33, P415, DOI 10.1177/0272989X12451058
   Song YP, 2021, WOUND REPAIR REGEN, V29, P20, DOI 10.1111/wrr.12863
   Srivastava RN, 2016, INT WOUND J, V13, P343, DOI 10.1111/iwj.12309
   Stevenson R, 2013, INT J NURS STUD, V50, P1550, DOI 10.1016/j.ijnurstu.2013.04.001
   Tauro LF, 2007, INDIAN J PLAST SURG, V40, P133, DOI 10.4103/0970-0358.33429
   Thompson SG, 1999, STAT MED, V18, P2693, DOI 10.1002/(SICI)1097-0258(19991030)18:20<2693::AID-SIM235>3.0.CO;2-V
   Ulrika K, 2022, INT WOUND J, V19, P1736, DOI 10.1111/iwj.13779
   US Food and Drug Administration, 2011, FDA SAF COMM UPD SER
   VanGilder C, 2017, J WOUND OSTOMY CONT, V44, P20, DOI 10.1097/WON.0000000000000292
   Wagstaff MJD, 2014, WOUND REPAIR REGEN, V22, P205, DOI 10.1111/wrr.12146
   Walker RM, 2017, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011332.pub2
   Wanner MB, 2003, SCAND J PLAST RECONS, V37, P28
   Wild T, 2008, INT WOUND J, V5, P641, DOI 10.1111/j.1742-481X.2007.00407.x
   Zhang Cheng, 2012, Zhonghua Yi Xue Za Zhi, V92, P2862
NR 99
TC 27
Z9 33
U1 5
U2 38
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1469-493X
EI 1361-6137
J9 COCHRANE DB SYST REV
JI Cochrane Database Syst Rev.
PY 2023
IS 5
AR CD011334
DI 10.1002/14651858.CD011334.pub3
PG 61
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA KU3M1
UT WOS:001182438700033
PM 37232410
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Phoon, PHY
   Hwang, NC
AF Phoon, Priscilla Hui Yi
   Hwang, Nian Chih
TI Deep Sternal Wound Infection: Diagnosis, Treatment and Prevention
SO JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
LA English
DT Review
DE sternal instability; wound dehiscence; cardiac surgery; prevention;
   treatment; management of mediastinitis
ID INTERNAL THORACIC ARTERY; VACUUM-ASSISTED CLOSURE; SURGICAL-SITE
   INFECTION; OPEN-HEART-SURGERY; POST-STERNOTOMY MEDIASTINITIS; PREDICTIVE
   SCORING SYSTEM; CORONARY-BYPASS SURGERY; LONG-TERM SURVIVAL;
   RISK-FACTORS; CARDIAC-SURGERY
AB Deep sternal wound infection (DSWI) is a rare but potentially devastating complication of median sternotomy performed in cardiac surgery. The incidence of DSWI is reported to be between 0.2% and 3%. Identifying high-risk patients and strategies to optimize risk factors plays an important role in reducing the incidence of DSWI. Management of DSWI can be complex and may require a multidisciplinary team approach involving infectious disease specialists, microbiologists, as well as cardiothoracic and plastic surgeons. Early detection, appropriate antibiotic treatment, aggressive surgical debridement, and use of regional muscle flaps have significantly improved treatment outcomes. (C) 2019 Elsevier Inc. All rights reserved.
C1 [Phoon, Priscilla Hui Yi; Hwang, Nian Chih] Singapore Gen Hosp, Dept Anaesthesiol, Singapore, Singapore.
   [Phoon, Priscilla Hui Yi; Hwang, Nian Chih] Natl Heart Ctr, Dept Cardiothorac Anaesthesia, Singapore, Singapore.
C3 Singapore General Hospital; National Heart Centre Singapore
RP Hwang, NC (通讯作者)，Natl Heart Ctr, Cardiothorac Anaesthesia, 1 Hosp Dr, Singapore 169608, Singapore.
EM hwang.nian.chih@singhealth.com.sg
OI Hwang, Nian Chih/0000-0002-1220-345X
CR Abu-Omar Y, 2017, EUR J CARDIO-THORAC, V51, P10, DOI 10.1093/ejcts/ezw326
   Akman C, 2004, CLIN RADIOL, V59, P573, DOI 10.1016/j.crad.2003.12.001
   Ammerlaan HSM, 2009, CLIN INFECT DIS, V48, P922, DOI 10.1086/597291
   Andreas M, 2017, INTERACT CARDIOV TH, V25, P6, DOI 10.1093/icvts/ivx032
   [Anonymous], 2008, SURG SIT INF PREV TR
   [Anonymous], 2019, J Clin Med
   Ariyaratnam P, 2010, INTERACT CARDIOV TH, V11, P543, DOI 10.1510/icvts.2010.237883
   Ashley ESD, 2004, CLIN INFECT DIS, V38, P1555, DOI 10.1086/420819
   Baillot R, 2010, EUR J CARDIO-THORAC, V37, P880, DOI 10.1016/j.ejcts.2009.09.023
   Balachandran S, 2016, ANN THORAC SURG, V102, P2109, DOI 10.1016/j.athoracsur.2016.05.047
   Banbury MK, 2006, J AM COLL SURGEONS, V202, P131, DOI 10.1016/j.jamcollsurg.2005.08.028
   Sá MPBD, 2013, INTERACT CARDIOV TH, V16, P849, DOI 10.1093/icvts/ivt012
   Sá MPBO, 2017, BRAZ J CARDIOVA SURG, V32, P1, DOI 10.21470/1678-9741-2016-0030
   Bindu Barkha, 2017, J Anaesthesiol Clin Pharmacol, V33, P306, DOI [10.4103/joacp.joacp_334_16, 10.4103/joacp.JOACP_334_16]
   Bonacchi M, 2018, J THORAC DIS, V10, P5208, DOI 10.21037/jtd.2018.09.30
   Boodhwani M, 2006, CIRCULATION, V114, P766, DOI 10.1161/CIRCULATIONAHA.106.615427
   Borger MA, 1998, ANN THORAC SURG, V65, P1050, DOI 10.1016/S0003-4975(98)00063-0
   Bratzler Dale W., Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery
   Brunet F, 1996, J THORAC CARDIOV SUR, V111, P1200
   Bryan CS, 2013, TEX HEART I J, V40, P125
   Cabbabe EB, 2009, PLAST RECONSTR SURG, V123, P1490, DOI 10.1097/PRS.0b013e3181a205f9
   Carr JM, 2005, ANN THORAC SURG, V80, P902, DOI 10.1016/j.athoracsur.2005.03.105
   Celik S, 2011, J THORAC CARDIOV SUR, V141, P1398, DOI 10.1016/j.jtcvs.2011.01.042
   Chan M, 2016, DIAGN MICR INFEC DIS, V84, P261, DOI 10.1016/j.diagmicrobio.2015.11.011
   Charbonneau H, 2014, CLIN MICROBIOL INFEC, V20, pO197, DOI 10.1111/1469-0691.12369
   Cimochowski GE, 2001, ANN THORAC SURG, V71, P1572, DOI 10.1016/S0003-4975(01)02519-X
   Colombier S, 2013, MED SCI MONITOR, V19, P668, DOI 10.12659/MSM.889191
   Combes A, 2004, CLIN INFECT DIS, V38, P822, DOI 10.1086/381890
   COPELAND M, 1994, ARCH SURG-CHICAGO, V129, P757
   Crabtree Traves D, 2004, Semin Thorac Cardiovasc Surg, V16, P53
   Cutrell JB, 2016, AM J INFECT CONTROL, V44, P1302, DOI 10.1016/j.ajic.2016.03.027
   Dai CY, 2013, ANN THORAC SURG, V95, P1938, DOI 10.1016/j.athoracsur.2012.12.038
   Franco LMD, 2017, AM J INFECT CONTROL, V45, P343, DOI 10.1016/j.ajic.2016.12.003
   De Feo M, 2001, ANN THORAC SURG, V71, P324, DOI 10.1016/S0003-4975(00)02137-8
   de Jonge SW, 2017, MEDICINE, V96, DOI 10.1097/MD.0000000000006903
   De Paulis R, 2005, J THORAC CARDIOV SUR, V129, P536, DOI 10.1016/j.jtcvs.2004.07.059
   Edwards FH, 2006, ANN THORAC SURG, V81, P397, DOI 10.1016/j.athoracsur.2005.06.034
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Engelman R, 2007, ANN THORAC SURG, V83, P1569, DOI 10.1016/j.athoracsur.2006.09.046
   Engemann JJ, 2003, CLIN INFECT DIS, V36, P592, DOI 10.1086/367653
   Ennker IC, 2009, J PLAST RECONSTR AES, V62, P1479, DOI 10.1016/j.bjps.2008.05.017
   Filsoufi F, 2009, J CARDIOTHOR VASC AN, V23, P488, DOI 10.1053/j.jvca.2009.02.007
   Fleck TM, 2004, ANN PLAS SURG, V52, P310, DOI 10.1097/01.sap.0000105524.75597.e0
   Floros P, 2011, HEART LUNG CIRC, V20, P712, DOI 10.1016/j.hlc.2011.08.001
   Fowler VG, 2005, CIRCULATION, V112, pI358, DOI 10.1161/CIRCULATIONAHA.104.525790
   Friedman ND, 2007, INFECT CONT HOSP EP, V28, P1162, DOI 10.1086/519534
   Furnary AP, 2006, SEMIN THORAC CARDIOV, V18, P302, DOI 10.1053/j.semtcvs.2006.04.005
   Furnary AP, 2003, J THORAC CARDIOV SUR, V125, P1007, DOI 10.1067/mtc.2003.181
   Gårdlund B, 2002, EUR J CARDIO-THORAC, V21, P825, DOI 10.1016/S1010-7940(02)00084-2
   Gårdlund B, 2007, APMIS, V115, P989, DOI 10.1111/j.1600-0463.2007.00845.x
   Gatti G, 2018, INT J CARDIOL, V269, P67, DOI 10.1016/j.ijcard.2018.07.090
   Gatti G, 2016, EUR J CARDIO-THORAC, V49, P910, DOI 10.1093/ejcts/ezv208
   Goh SSC, 2017, J CARDIAC SURG, V32, P556, DOI 10.1111/jocs.13189
   Graf K, 2010, EUR J CARDIO-THORAC, V37, P893, DOI 10.1016/j.ejcts.2009.10.005
   Hamouda K, 2015, J CARDIOTHORAC SURG, V10, DOI 10.1186/s13019-015-0225-x
   Hanrahan TP, 2016, CRIT CARE, V20, DOI 10.1186/s13054-016-1426-y
   Harbarth S, 2002, ANTIMICROB AGENTS CH, V46, P1619, DOI 10.1128/AAC.46.6.1619-1628.2002
   Harbarth S, 2000, CIRCULATION, V101, P2916, DOI 10.1161/01.CIR.101.25.2916
   Hopf HW, 1997, ARCH SURG-CHICAGO, V132, P997
   Horan TC, 2008, AM J INFECT CONTROL, V36, P309, DOI 10.1016/j.ajic.2008.03.002
   Hussey LC, 1998, HEART LUNG, V27, P326, DOI 10.1016/S0147-9563(98)90053-X
   JENSEN JA, 1991, ARCH SURG-CHICAGO, V126, P1131
   Juhl AA, 2017, ANN THORAC CARDIOVAS, V23, P76, DOI 10.5761/atcs.oa.16-00196
   Kajimoto K, 2015, ANN THORAC SURG, V99, P1097, DOI 10.1016/j.athoracsur.2014.09.045
   Kallen AJ, 2005, INFECT CONT HOSP EP, V26, P916, DOI 10.1086/505453
   Kaul P, 2017, J CARDIOTHORAC SURG, V12, DOI 10.1186/s13019-017-0656-7
   KEELEY SB, 1987, ANN THORAC SURG, V44, P324, DOI 10.1016/S0003-4975(10)62088-7
   Khanlari B, 2010, J ANTIMICROB CHEMOTH, V65, P1799, DOI 10.1093/jac/dkq182
   Kowalewski M, 2017, J THORAC CARDIOV SUR, V154, P1320, DOI 10.1016/j.jtcvs.2017.06.004
   Kowalewski M, 2015, J THORAC CARDIOV SUR, V149, P1631, DOI 10.1016/j.jtcvs.2015.01.034
   Kramer R, 2008, ARCH SURG-CHICAGO, V143, P451, DOI 10.1001/archsurg.143.5.451
   KRETER B, 1992, J THORAC CARDIOV SUR, V104, P590
   Kubota H, 2013, J CARDIOTHORAC SURG, V8, DOI 10.1186/1749-8090-8-132
   Kurz A, 1996, NEW ENGL J MED, V334, P1209, DOI 10.1056/NEJM199605093341901
   Lador A, 2012, J ANTIMICROB CHEMOTH, V67, P541, DOI 10.1093/jac/dkr470
   Lazar HL, 2016, J THORAC CARDIOV SUR, V152, P962, DOI 10.1016/j.jtcvs.2016.01.060
   Lazar HL, 2014, J THORAC CARDIOV SUR, V148, P1035, DOI 10.1016/j.jtcvs.2014.06.045
   Lazar HL, 2011, J CARDIAC SURG, V26, P461, DOI 10.1111/j.1540-8191.2011.01300.x
   Lo S, 2014, ANN PLAS SURG, V73, P588, DOI 10.1097/SAP.0b013e318284084b
   Lu JCY, 2003, EUR J CARDIO-THORAC, V23, P943, DOI 10.1016/S1010-7940(03)00137-4
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Matros E, 2010, J THORAC CARDIOV SUR, V139, P680, DOI 10.1016/j.jtcvs.2009.10.006
   Mauermann WJ, 2006, ANESTHESIOLOGY, V105, P413, DOI 10.1097/00000542-200608000-00025
   McConeghy KW, 2009, PHARMACOTHERAPY, V29, P263, DOI 10.1592/phco.29.3.263
   McGregor WE, 1999, J THORAC CARDIOV SUR, V117, P1144, DOI 10.1016/S0022-5223(99)70251-5
   Mekontso-Dessap A, 2001, CLIN INFECT DIS, V32, P877, DOI 10.1086/319355
   Mertz D, 2011, ANN SURG, V254, P48, DOI 10.1097/SLA.0b013e318214b7e4
   Mets B, 2000, ACTA ANAESTH SCAND, V44, P261, DOI 10.1034/j.1399-6576.2000.440308.x
   Miyahara K, 2014, J THORAC CARDIOV SUR, V148, P2381, DOI 10.1016/j.jtcvs.2014.04.005
   Morisaki A, 2016, INTERACT CARDIOV TH, V23, P397, DOI 10.1093/icvts/ivw141
   Morisaki A, 2011, GEN THORAC CARDIOVAS, V59, P261, DOI 10.1007/s11748-010-0727-3
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Muñoz P, 2008, J HOSP INFECT, V68, P25, DOI 10.1016/j.jhin.2007.08.010
   Murphy GJ, 2015, NEW ENGL J MED, V372, P997, DOI 10.1056/NEJMoa1403612
   Nashef SAM, 1999, EUR J CARDIO-THORAC, V16, P9, DOI 10.1016/S1010-7940(99)00134-7
   OCONNOR GT, 1992, CIRCULATION, V85, P2110, DOI 10.1161/01.CIR.85.6.2110
   Omran AS, 2007, BMC INFECT DIS, V7, DOI 10.1186/1471-2334-7-112
   OTTINO G, 1987, ANN THORAC SURG, V44, P173, DOI 10.1016/S0003-4975(10)62035-8
   Pan L, 2017, J THORAC DIS, V9, P3031, DOI 10.21037/jtd.2017.08.41
   Paone G, 2013, ANN THORAC SURG, V96, P1279, DOI 10.1016/j.athoracsur.2013.05.045
   Paul M, 2007, J THORAC CARDIOV SUR, V133, P397, DOI 10.1016/j.jtcvs.2006.10.012
   Perrotti A, 2017, SURG INFECT, V18, P181, DOI 10.1089/sur.2016.150
   Petzina R, 2010, EUR J CARDIO-THORAC, V38, P110, DOI 10.1016/j.ejcts.2010.01.028
   Pilarczyk K, 2015, J CARDIOTHOR VASC AN, V29, P1573, DOI 10.1053/j.jvca.2015.04.002
   Raja SG, 2015, INT J SURG, V16, P69, DOI 10.1016/j.ijsu.2015.02.008
   Rashed A, 2018, J THORAC DIS, V10, P3568, DOI 10.21037/jtd.2018.06.20
   Ridderstolpe L, 2001, EUR J CARDIO-THORAC, V20, P1168, DOI 10.1016/S1010-7940(01)00991-5
   Risnes I, 2010, ANN THORAC SURG, V89, P1502, DOI 10.1016/j.athoracsur.2010.02.038
   ROBICSEK F, 1977, J THORAC CARDIOV SUR, V73, P267
   Robinson Penelope J, 2007, Interact Cardiovasc Thorac Surg, V6, P167
   Roy MC, 2000, INFECT CONT HOSP EP, V21, P186, DOI 10.1086/501741
   Russo PL, 2002, INFECT CONT HOSP EP, V23, P372, DOI 10.1086/502068
   Sakamoto Hiroaki, 2003, Ann Thorac Cardiovasc Surg, V9, P226
   Juan RS, 2007, J THORAC CARDIOV SUR, V134, P670, DOI 10.1016/j.jtcvs.2007.04.010
   SARR MG, 1984, ANN THORAC SURG, V38, P415, DOI 10.1016/S0003-4975(10)62300-4
   Schimmer C, 2008, EUR J CARDIO-THORAC, V34, P132, DOI 10.1016/j.ejcts.2008.04.006
   Sears ED, 2016, WORLD J SURG, V40, P2673, DOI 10.1007/s00268-016-3598-7
   Septimus EJ, 2016, CLIN MICROBIOL REV, V29, P201, DOI 10.1128/CMR.00049-15
   Sessler DI, 2001, ANESTHESIOLOGY, V95, P531, DOI 10.1097/00000542-200108000-00040
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Sofer D, 1999, ANN SURG, V229, P585, DOI 10.1097/00000658-199904000-00020
   Tegnell A, 2000, ANN THORAC SURG, V69, P1104, DOI 10.1016/S0003-4975(99)01563-5
   Thompson KM, 2011, ANN SURG, V254, P430, DOI 10.1097/SLA.0b013e31822cc0ad
   Trick WE, 2000, J THORAC CARDIOV SUR, V119, P108, DOI 10.1016/S0022-5223(00)70224-8
   van Rijen MML, 2008, J ANTIMICROB CHEMOTH, V61, P254, DOI 10.1093/jac/dkm480
   van Wingerden JJ, 2014, J CARDIOTHORAC SURG, V9, DOI 10.1186/s13019-014-0179-4
   VANDERSALM TJ, 1989, J THORAC CARDIOV SUR, V98, P618
   Vos RJ, 2018, J HOSP INFECT, V100, P411, DOI 10.1016/j.jhin.2018.05.026
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
   Wang FD, 2000, J CARDIOVASC SURG, V41, P709
   Webster J, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004985.pub5
   Wu LZ, 2016, PLAST RECONSTR SURG, V137, p414E, DOI 10.1097/01.prs.0000475785.14328.b2
   Yavuz SS, 2014, MED PRIN PRACT, V23, P517, DOI 10.1159/000365055
   Yi GJ, 2014, CIRCULATION, V130, P539, DOI 10.1161/CIRCULATIONAHA.113.004255
   Yusuf E, 2018, INFECT DRUG RESIST, V11, P961, DOI 10.2147/IDR.S130172
   Zacharias A, 1996, CHEST, V110, P1173, DOI 10.1378/chest.110.5.1173
   Zeitani J, 2006, J THORAC CARDIOV SUR, V132, P38, DOI 10.1016/j.jtcvs.2006.03.015
   Zhang L, 2006, ANN THORAC SURG, V81, P1379, DOI 10.1016/j.athoracsur.2005.11.003
   Zhang RF, 2018, J PLAST RECONSTR AES, V71, P1768, DOI 10.1016/j.bjps.2018.07.017
NR 140
TC 81
Z9 107
U1 1
U2 17
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1053-0770
EI 1532-8422
J9 J CARDIOTHOR VASC AN
JI J. Cardiothorac. Vasc. Anesth.
PD JUN
PY 2020
VL 34
IS 6
BP 1602
EP 1613
DI 10.1053/j.jvca.2019.09.019
PG 12
WC Anesthesiology; Cardiac & Cardiovascular Systems; Respiratory System;
   Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Anesthesiology; Cardiovascular System & Cardiology; Respiratory System
GA LJ5PJ
UT WOS:000530217000040
PM 31623967
DA 2026-07-24
ER

PT J
AU Van Noten, C
   van Doorn, KJ
   Vermander, E
   Vlayen, S
   Verpooten, GA
   Couttenye, MM
AF Van Noten, Charlotte
   van Doorn, Karin Janssen
   Vermander, Evert
   Vlayen, Sonja
   Verpooten, Gert A.
   Couttenye, Marie-Madeleine
TI Maximal conservative therapy of calcific uremic arteriolopathy
SO CLINICAL NEPHROLOGY
LA English
DT Article
DE calciphylaxis; cinacalcet; sodium thiosulfate; wound care
ID CALCIPHYLAXIS
AB We present the case of a 61-year-old female patient in long-term hemodialysis who developed calcific uremic arteriolopathy (CUA) upon administration of the oral calcimimetic agent cinacalcet for treatment of secondary hyperparathyroidism. In May 2009, the baseline serum values were parathormone (PTH) 310 pg/ml, calcium 9.1 mg/dl and phosphorous 6.9 mg/dl. Necrotic wounds in the suprapubic fat tissue were successfully treated first, by correcting the calcium phosphorous product; second, through treatment with sodium thiosulfate and third, through intensive wound care with hyperbaric oxygen therapy and vacuum-assisted closure therapy, with no need for parathyroidectomy. Multiple factors have been described to play a role in the development of CUA. Based on the findings of this case, the treatment of CUA should be aimed at correcting different causes simultaneously.
C1 [Van Noten, Charlotte; van Doorn, Karin Janssen; Verpooten, Gert A.; Couttenye, Marie-Madeleine] Univ Antwerp Hosp, Dept Nephrol Hypertens, B-2650 Antwerp, Belgium.
   [Vermander, Evert] Univ Antwerp Hosp, Dept Dermatol, B-2650 Antwerp, Belgium.
   [Vlayen, Sonja] Univ Antwerp Hosp, Dept Nursing, B-2650 Antwerp, Belgium.
   [Verpooten, Gert A.; Couttenye, Marie-Madeleine] Univ Antwerp, Antwerp, Belgium.
C3 University of Antwerp; University of Antwerp; University of Antwerp;
   University of Antwerp
RP Couttenye, MM (通讯作者)，Univ Antwerp Hosp, Dept Nephrol Hypertens, Wilrijkstr 10, B-2650 Antwerp, Belgium.
EM marie.couttenye@ua.ac.be
RI Couttenye, Marie/E-3473-2017
OI Couttenye, Marie/0000-0003-0324-2171
CR Angelis M, 1997, SURGERY, V122, P1083, DOI 10.1016/S0039-6060(97)90212-9
   KENT RB, 1994, SOUTHERN MED J, V87, P278, DOI 10.1097/00007611-199402000-00029
   Naeyaert JM, 2000, COMPLICATIONS DIALYS, P455
   Rogers NM, 2008, CURR OPIN NEPHROL HY, V17, P629, DOI 10.1097/MNH.0b013e32830f4566
   Santos PW, CALCIPHYLAXIS
   Schlieper G, 2009, NAT REV NEPHROL, V5, P539, DOI 10.1038/nrneph.2009.99
   Weenig RH, 2007, J AM ACAD DERMATOL, V56, P569, DOI 10.1016/j.jaad.2006.08.065
NR 7
TC 1
Z9 1
U1 0
U2 1
PU DUSTRI-VERLAG DR KARL FEISTLE
PI DEISENHOFEN-MUENCHEN
PA BAHNHOFSTRASSE 9 POSTFACH 49, D-82032 DEISENHOFEN-MUENCHEN, GERMANY
SN 0301-0430
J9 CLIN NEPHROL
JI Clin. Nephrol.
PD JUL
PY 2012
VL 78
IS 1
BP 61
EP 63
DI 10.5414/CN107016
PG 3
WC Urology & Nephrology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Urology & Nephrology
GA 226OU
UT WOS:000325046500009
PM 22732339
DA 2026-07-24
ER

PT J
AU Loske, G
AF Loske, G.
TI Endoscopic negative pressure therapy of the upper gastrointestinal tract
SO CHIRURG
LA English
DT Review
DE Endoscopic vacuum therapy; Esophagus; Drainage; Anastomotic leakage;
   Perforation
ID OPEN-PORE FILM; VACUUM-ASSISTED CLOSURE; ANASTOMOTIC LEAKAGE; DUODENAL
   PERFORATION; TREATMENT OPTIONS; DRAINAGE; INSUFFICIENCY; DEVICE;
   ESOPHAGECTOMY; GASTROSTOMY
AB Endoscopic negative pressure therapy (ENPT) has been adapted for upper gastrointestinal tract applications. More than 400patients have already been treated with ENPT due to transmural defects in the upper gastrointestinal tract, with asuccess rate of 87%. The greatest experience exists for the treatment of anastomotic leakages and perforations of the esophagus. The ENPT is also used in the duodenum, pancreas and for complications after bariatric surgery. There are new indications that go beyond treatment in complication management. Innovative drainage types and endoscopic techniques have been developed that broaden the spectrum of applications. The aim of this article is to give an overview of the current status of ENPT in the upper gastrointestinal tract.
C1 [Loske, G.] Katholisches Marienkrankenhaus Hamburg gGmbH, Dept Gen Visceral Thorac & Vasc Surg, Alfredstr 9, D-22087 Hamburg, Germany.
C3 St. Marien Hospital
RP Loske, G (通讯作者)，Katholisches Marienkrankenhaus Hamburg gGmbH, Dept Gen Visceral Thorac & Vasc Surg, Alfredstr 9, D-22087 Hamburg, Germany.
EM loske.chir@marienkrankenhaus.org
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bludau M, 2018, SURG ENDOSC, V32, P1906, DOI 10.1007/s00464-017-5883-4
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Christogianni V, 2018, 135 C GERM SOC SURG
   Fähndrich M, 2014, ENDOSCOPY, V46, pE459, DOI 10.1055/s-0034-1377554
   Feisthammel J, 2013, ZBL CHIR, V138, P295, DOI 10.1055/s-0031-1283960
   Fischer A, 2016, ENDOSC INT OPEN, V4, pE937, DOI 10.1055/s-0042-111078
   Fraga JC, 2018, J THORAC CARDIOV SUR, V156, pE193, DOI 10.1016/j.jtcvs.2018.04.061
   Glatz T, 2015, ENDOSCOPY, V47, pE567, DOI 10.1055/s-0034-1393369
   Heits N, 2014, ANN THORAC SURG, V97, P1029, DOI 10.1016/j.athoracsur.2013.11.014
   Hochberger J, 2016, ENDOSCOPY, V48, pE401, DOI 10.1055/s-0042-122419
   Hwang JJ, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000003416
   Kelm M, 2017, INT J SURG CASE REP, V41, P401, DOI 10.1016/j.ijscr.2017.11.022
   Kirschner M, 1926, ARCH KLIN CHIR, V142, P253
   Knoop RF, 2017, ENDOSCOPY, V49, P1011, DOI 10.1055/s-0043-113552
   Krajinovic K, 2016, SURG CASE REP, V2, DOI 10.1186/s40792-016-0243-5
   Kuehn F, 2017, SURG ENDOSC, V31, P3449, DOI 10.1007/s00464-016-5404-x
   Kuehn F, 2016, J GASTROINTEST SURG, V20, P237, DOI 10.1007/s11605-015-3044-4
   Laukoetter MG, 2017, SURG ENDOSC, V31, P2687, DOI 10.1007/s00464-016-5265-3
   Lee So Young, 2018, Korean J Thorac Cardiovasc Surg, V51, P76, DOI [10.5090/kjtcs.2018.51.1.76, 10.5090/kjtcs.2018.51.1.76]
   Lock JF, 2016, Z GASTROENTEROL, V54, DOI [10.1055/s-0036-1587228, 10.1055/s-0036-1587228, DOI 10.1055/S-0036-1587228]
   Loske G, 2018, CHIRURG, V89, P887, DOI 10.1007/s00104-018-0715-1
   Loske G, 2016, CHIRURG, V87, P790, DOI 10.1007/s00104-016-0275-1
   Loske G, 2016, CHIRURG, V87, P676, DOI 10.1007/s00104-016-0185-2
   Loske G, 2015, CHIRURG, V86, P486, DOI 10.1007/s00104-015-2993-1
   Loske G, 2012, ENDOSCOPY, V44, pE94, DOI 10.1055/s-0031-1291698
   Loske G, 2011, ENDOSCOPY, V43, P540, DOI 10.1055/s-0030-1256345
   Loske G, 2010, ENDOSKOPIE HEUTE, V23, P267, DOI 10.1055/s-0030-1262709
   Loske G, 2010, ENDOSCOPY, V42, pE109, DOI 10.1055/s-0029-1243947
   Loske G, 2009, ZBL CHIR, V134, P267, DOI 10.1055/s-0028-1098764
   Loske G, 2007, VACUUMSCHWAMMTHERAPI
   Loske G, 2018, CHIR PRAX, V83, P596
   Loske G, 2017, UNITED EUROPEAN G S1, V5, pA493
   Loske G, 2018, INNOV SURG SCI SUPPL, V3, pS15
   Loske G, 2018, ENDOSC INT OPEN, V6, pE865, DOI 10.1055/a-0599-5886
   Loske G, 2017, ENDOSCOPY, V49, pE294, DOI 10.1055/s-0043-118211
   Loske G, 2017, ENDOSCOPY, V49, pE300, DOI 10.1055/s-0043-119346
   Loske G, 2016, ENDOSCOPY, V48, pE148, DOI 10.1055/s-0042-106576
   Loske G, 2016, ENDOSCOPY, V48, pE154, DOI 10.1055/s-0042-105364
   Loske G, 2015, ENDOSC INT OPEN, V3, pE547, DOI 10.1055/s-0034-1392566
   Loske G, 2015, ENDOSCOPY, V47, pE577, DOI 10.1055/s-0034-1393388
   Loske G, 2014, ENDOSCOPY, V46, pE575, DOI 10.1055/s-0034-1390913
   Loske G, 2011, VISZERALMEDIZIN, V27, P166, DOI 10.1159/000328082
   Loske G, 2010, SURG ENDOSC, V24, P2531, DOI 10.1007/s00464-010-0998-x
   Loske G, 2009, GASTROINTEST ENDOSC, V69, P601, DOI 10.1016/j.gie.2008.06.058
   Manfredi MA, 2018, J PEDIATR GASTR NUTR, V67, P706, DOI 10.1097/MPG.0000000000002073
   Mencio MA, 2018, SURG ENDOSC, V32, P3349, DOI 10.1007/s00464-018-6055-x
   Mennigen R, 2015, J GASTROINTEST SURG, V19, P1229, DOI 10.1007/s11605-015-2847-7
   Mennigen R, 2014, WORLD J GASTROENTERO, V20, P7767, DOI 10.3748/wjg.v20.i24.7767
   Möschler O, 2015, ENDOSC INT OPEN, V3, pE554, DOI 10.1055/s-0034-1392568
   Neumann PA, 2017, ENDOSCOPY, V49, P498, DOI 10.1055/s-0042-123188
   Ooi G, 2018, ANZ J SURG, V88, pE257, DOI 10.1111/ans.13837
   Pournaras DJ, 2018, WORLD J SURG, V42, P2507, DOI 10.1007/s00268-018-4463-7
   Schniewind B, 2013, SURG ENDOSC, V27, P3883, DOI 10.1007/s00464-013-2998-0
   Schorsch, 2013, VIDEO J ENCY GI ENDO, V1, P51, DOI [10.1016/S2212-0971(13)70024-4, DOI 10.1016/S2212-0971(13)70024-4]
   Schorsch T, 2014, CHIRURG, V85, P1081, DOI 10.1007/s00104-014-2764-4
   Schorsch T, 2013, ENDOSCOPY, V45, pE141, DOI 10.1055/s-0032-1326260
   Scott RB, 2017, CTS-CLIN TRANSL SCI, V10, P35, DOI 10.1111/cts.12427
   Tan B, 2015, GUT, V64, pA120, DOI 10.1136/gutjnl-2015-309861.245
   Wallstabe I, 2012, ENDOSCOPY, V44, pE49, DOI 10.1055/s-0031-1291525
   Wallstabe I, 2011, ENDOSCOPY, V43, pE312, DOI 10.1055/s-0030-1256643
   Wallstabe I, 2007, Z GASTROENTEROL, DOI [10.1055/s-2007-988573, DOI 10.1055/S-2007-988573]
   Weidenhagen R, 2010, ANN THORAC SURG, V90, P1674, DOI 10.1016/j.athoracsur.2010.07.007
   Yoo T, 2018, GASTROINTEST ENDOSC, V87, P1363, DOI 10.1016/j.gie.2017.11.019
NR 64
TC 45
Z9 48
U1 0
U2 4
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0009-4722
EI 1433-0385
J9 CHIRURG
JI Chirurg
PD JAN
PY 2019
VL 90
SU 1
BP S1
EP S6
DI 10.1007/s00104-018-0727-x
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HI8OX
UT WOS:000456716700001
PM 30456644
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Loske, G
AF Loske, G.
TI Endoscopic negative pressure therapy of the upper gastrointestinal
   tract. German version
SO CHIRURG
LA German
DT Article
DE Endoscopic vacuum therapy; Esophagus; Drainage; Anastomotic leakage;
   Perforation
ID OPEN-PORE FILM; VACUUM-ASSISTED CLOSURE; ANASTOMOTIC LEAKAGE; DUODENAL
   PERFORATION; TREATMENT OPTIONS; DRAINAGE; DEVICE; ESOPHAGECTOMY;
   INSUFFICIENCY; GASTROSTOMY
AB Endoscopic negative pressure therapy (ENPT) has been adapted for upper gastrointestinal tract applications. More than 400 patients have already been treated with ENPT due to transmural defects in the upper gastrointestinal tract, with a success rate of 87%. The greatest experience exists for the treatment of anastomotic leakages and perforations of the esophagus. The ENPT is also used in the duodenum, pancreas and for complications after bariatric surgery. There are new indications that go beyond treatment in complication management. Innovative drainage types and endoscopic techniques have been developed that broaden the spectrum of applications. The aim of this article is to give an overview of the current status of ENPT in the upper gastrointestinal tract.
C1 [Loske, G.] Katholisches Marienkrankenhaus Hamburg gGmbH, Klin Allgemein Viszeral Thorax & Gefasschirurg, Alfredstr 9, D-22087 Hamburg, Germany.
C3 St. Marien Hospital
RP Loske, G (通讯作者)，Katholisches Marienkrankenhaus Hamburg gGmbH, Klin Allgemein Viszeral Thorax & Gefasschirurg, Alfredstr 9, D-22087 Hamburg, Germany.
EM loske.chir@marienkrankenhaus.org
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bludau M, 2018, SURG ENDOSC, V32, P1906, DOI 10.1007/s00464-017-5883-4
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Christogianni V, 2018, 135 C GERM SOC SURG
   Fähndrich M, 2014, ENDOSCOPY, V46, pE459, DOI 10.1055/s-0034-1377554
   Feisthammel J, 2013, ZBL CHIR, V138, P295, DOI 10.1055/s-0031-1283960
   Fischer A, 2016, ENDOSC INT OPEN, V4, pE937, DOI 10.1055/s-0042-111078
   Fraga JC, 2018, J THORAC CARDIOV SUR, V156, pE193, DOI 10.1016/j.jtcvs.2018.04.061
   Glatz T, 2015, ENDOSCOPY, V47, pE567, DOI 10.1055/s-0034-1393369
   Heits N, 2014, ANN THORAC SURG, V97, P1029, DOI 10.1016/j.athoracsur.2013.11.014
   Hochberger J, 2016, ENDOSCOPY, V48, pE401, DOI 10.1055/s-0042-122419
   Hwang JJ, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000003416
   Kelm M, 2017, INT J SURG CASE REP, V41, P401, DOI 10.1016/j.ijscr.2017.11.022
   Kirschner M, 1926, ARCH KLIN CHIR, V142, P253
   Knoop RF, 2017, ENDOSCOPY, V49, P1011, DOI 10.1055/s-0043-113552
   Krajinovic K, 2016, SURG CASE REP, V2, DOI 10.1186/s40792-016-0243-5
   Kuehn F, 2017, SURG ENDOSC, V31, P3449, DOI 10.1007/s00464-016-5404-x
   Kuehn F, 2016, J GASTROINTEST SURG, V20, P237, DOI 10.1007/s11605-015-3044-4
   Laukoetter MG, 2017, SURG ENDOSC, V31, P2687, DOI 10.1007/s00464-016-5265-3
   Lee So Young, 2018, Korean J Thorac Cardiovasc Surg, V51, P76, DOI [10.5090/kjtcs.2018.51.1.76, 10.5090/kjtcs.2018.51.1.76]
   Lock JF, 2016, Z GASTROENTEROL, V54, DOI [10.1055/s-0036-1587228, 10.1055/s-0036-1587228, DOI 10.1055/S-0036-1587228]
   Loske G, 2018, CHIRURG, V89, P887, DOI 10.1007/s00104-018-0715-1
   Loske G, 2016, CHIRURG, V87, P790, DOI 10.1007/s00104-016-0275-1
   Loske G, 2016, CHIRURG, V87, P676, DOI 10.1007/s00104-016-0185-2
   Loske G, 2015, CHIRURG, V86, P486, DOI 10.1007/s00104-015-2993-1
   Loske G, 2012, ENDOSCOPY, V44, pE94, DOI 10.1055/s-0031-1291698
   Loske G, 2011, ENDOSCOPY, V43, P540, DOI 10.1055/s-0030-1256345
   Loske G, 2010, ENDOSKOPIE HEUTE, V23, P267, DOI 10.1055/s-0030-1262709
   Loske G, 2010, ENDOSCOPY, V42, pE109, DOI 10.1055/s-0029-1243947
   Loske G, 2009, ZBL CHIR, V134, P267, DOI 10.1055/s-0028-1098764
   Loske G, 2007, VACUUMSCHWAMMTHERAPI
   Loske G, 2018, CHIR PRAX, V83, P596
   Loske G, 2017, UNITED EUROPEAN G S1, V5, pA493
   Loske G, 2018, INNOV SURG SCI SUPPL, V3, pS15
   Loske G, 2018, ENDOSC INT OPEN, V6, pE865, DOI 10.1055/a-0599-5886
   Loske G, 2017, ENDOSCOPY, V49, pE294, DOI 10.1055/s-0043-118211
   Loske G, 2017, ENDOSCOPY, V49, pE300, DOI 10.1055/s-0043-119346
   Loske G, 2016, ENDOSCOPY, V48, pE148, DOI 10.1055/s-0042-106576
   Loske G, 2016, ENDOSCOPY, V48, pE154, DOI 10.1055/s-0042-105364
   Loske G, 2015, ENDOSC INT OPEN, V3, pE547, DOI 10.1055/s-0034-1392566
   Loske G, 2015, ENDOSCOPY, V47, pE577, DOI 10.1055/s-0034-1393388
   Loske G, 2014, ENDOSCOPY, V46, pE575, DOI 10.1055/s-0034-1390913
   Loske G, 2011, VISZERALMEDIZIN, V27, P166, DOI 10.1159/000328082
   Loske G, 2010, SURG ENDOSC, V24, P2531, DOI 10.1007/s00464-010-0998-x
   Loske G, 2009, GASTROINTEST ENDOSC, V69, P601, DOI 10.1016/j.gie.2008.06.058
   Manfredi MA, 2018, J PEDIATR GASTR NUTR, V67, P706, DOI 10.1097/MPG.0000000000002073
   Mencio MA, 2018, SURG ENDOSC, V32, P3349, DOI 10.1007/s00464-018-6055-x
   Mennigen R, 2015, J GASTROINTEST SURG, V19, P1229, DOI 10.1007/s11605-015-2847-7
   Mennigen R, 2014, WORLD J GASTROENTERO, V20, P7767, DOI 10.3748/wjg.v20.i24.7767
   Möschler O, 2015, ENDOSC INT OPEN, V3, pE554, DOI 10.1055/s-0034-1392568
   Neumann PA, 2017, ENDOSCOPY, V49, P498, DOI 10.1055/s-0042-123188
   Ooi G, 2018, ANZ J SURG, V88, pE257, DOI 10.1111/ans.13837
   Pournaras DJ, 2018, WORLD J SURG, V42, P2507, DOI 10.1007/s00268-018-4463-7
   Schniewind B, 2013, SURG ENDOSC, V27, P3883, DOI 10.1007/s00464-013-2998-0
   Schorsch, 2013, VIDEO J ENCY GI ENDO, V1, P51, DOI [10.1016/S2212-0971(13)70024-4, DOI 10.1016/S2212-0971(13)70024-4]
   Schorsch T, 2014, CHIRURG, V85, P1081, DOI 10.1007/s00104-014-2764-4
   Schorsch T, 2013, ENDOSCOPY, V45, pE141, DOI 10.1055/s-0032-1326260
   Scott RB, 2017, CTS-CLIN TRANSL SCI, V10, P35, DOI 10.1111/cts.12427
   Tan B, 2015, GUT, V64, pA120, DOI 10.1136/gutjnl-2015-309861.245
   Wallstabe I, 2012, ENDOSCOPY, V44, pE49, DOI 10.1055/s-0031-1291525
   Wallstabe I, 2011, ENDOSCOPY, V43, pE312, DOI 10.1055/s-0030-1256643
   Wallstabe I, 2007, Z GASTROENTEROL, DOI [10.1055/s-2007-988573, DOI 10.1055/S-2007-988573]
   Weidenhagen R, 2010, ANN THORAC SURG, V90, P1674, DOI 10.1016/j.athoracsur.2010.07.007
   Yoo T, 2018, GASTROINTEST ENDOSC, V87, P1363, DOI 10.1016/j.gie.2017.11.019
NR 64
TC 5
Z9 6
U1 0
U2 2
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0009-4722
EI 1433-0385
J9 CHIRURG
JI Chirurg
PD DEC
PY 2018
VL 89
IS 12
BP 952
EP 959
DI 10.1007/s00104-018-0728-9
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA HD1WS
UT WOS:000452303700003
PM 30306230
OA hybrid
DA 2026-07-24
ER

PT J
AU Janis, JE
   Kwon, RK
   Lalonde, DH
AF Janis, Jeffrey E.
   Kwon, Robert K.
   Lalonde, Donald H.
TI A Practical Guide to Wound Healing
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; GLYCATION END-PRODUCTS; PLATELET-RICH PLASMA;
   HYPERBARIC-OXYGEN; BECAPLERMIN GEL; SKIN; COLLAGEN; RADIATION; THERAPY;
   RECONSTRUCTION
AB Learning Objectives: After reading this article, the participant should be able to: 1. Understand the basic stages of wound healing. 2. Apply current techniques to achieve wound closure. 3. Manage patients with simple and complex wounds effectively.
   Summary: While wound healing can still be divided into stages, numerous intrinsic and extrinsic factors must be considered as well if clinical success is to be reliably achieved. While a routine wound may require nothing more than a simple dressing, the more complex and challenging wounds may benefit from more advanced therapy, such as growth factor applications, specialized dressings, or adjunctive therapy. This article will attempt to provide a concise summary of the advances in the basic and clinical science of wound healing. (Plast. Reconstr. Surg. 125: 230e, 2010.)
C1 [Janis, Jeffrey E.] Univ Texas SW Med Ctr Dallas, Dept Plast Surg, Dallas, TX 75390 USA.
   Dalhousie Univ, Dept Plast Surg, St John, NB, Canada.
C3 University of Texas System; University of Texas Southwestern Medical
   Center; Dalhousie University
RP Janis, JE (通讯作者)，Univ Texas SW Med Ctr Dallas, Dept Plast Surg, 1801 Inwood Rd, Dallas, TX 75390 USA.
EM jeffrey.janis@utsouthwestern.edu
RI /JQI-6551-2023; Janis, Jeffrey/W-6760-2019
OI Janis, Jeffrey/0000-0001-6103-4798; Lalonde, Donald/0000-0001-7073-2715
CR Alqahtani Moraya, 2006, Can J Plast Surg, V14, P25
   Anstead G M, 1998, Adv Wound Care, V11, P277
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Attinger C.E, 2006, PLAST RECONSTR SURG, V117
   BAILEY AJ, 1975, BIOCHEM BIOPH RES CO, V66, P1160, DOI 10.1016/0006-291X(75)90480-5
   Barnea Y, 2004, PLAST RECONSTR SURG, V113, P862, DOI 10.1097/01.PRS.0000105339.41838.D2
   Bashir A, 2007, PAK J PHARM SCI, V20, P299
   Bello Y M, 2002, J Wound Care, V11, P182
   BEVILACQUA MP, 1985, J CLIN INVEST, V76, P2003, DOI 10.1172/JCI112200
   BEZWADA RS, 1995, BIOMATERIALS, V16, P1141, DOI 10.1016/0142-9612(95)93577-Z
   BLAIR SD, 1990, BRIT J SURG, V77, P568, DOI 10.1002/bjs.1800770534
   Boulton Andrew J M, 2008, Foot Ankle Surg, V14, P120, DOI 10.1016/j.fas.2008.05.004
   Broughton G, 2006, PLAST RECONSTR SURG, V117, p12S, DOI 10.1097/01.prs.0000225430.42531.c2
   Cavorsi J, 2006, WOUND REPAIR REGEN, V14, P102, DOI 10.1111/j.1743-6109.2006.00098.x
   Choudry U, 2008, PLAST RECONSTR SURG, V122, P479, DOI 10.1097/PRS.0b013e31817d60e0
   Chow LWC, 2003, WOUND REPAIR REGEN, V11, P326, DOI 10.1046/j.1524-475X.2003.11503.x
   COHEN IK, 1977, SURGERY, V82, P15
   COHEN SC, 1975, SURGERY, V78, P238
   Coleman SR, 2006, PLAST RECONSTR SURG, V118, p108S, DOI 10.1097/01.prs.0000234610.81672.e7
   DANFORTH DN, 1990, AM SURGEON, V56, P6
   DAVID DJ, 1972, BMJ-BRIT MED J, V2, P614, DOI 10.1136/bmj.2.5814.614
   Daya M, 2008, PLAST RECONSTR SURG, V122, P1047, DOI 10.1097/PRS.0b013e3181858c68
   Debus ES, 1997, EUR SURG RES, V29, P52, DOI 10.1159/000129507
   DESMOULIERE A, 1993, J CELL BIOL, V122, P103, DOI 10.1083/jcb.122.1.103
   Diegelmann RF, 2003, METH MOLEC MED, V78, P349
   Dinh TL, 2006, PLAST RECONSTR SURG, V117, p152S, DOI 10.1097/01.prs.0000222534.79915.d3
   Ducasse E, 2003, J MAL VASCUL, V28, P68
   EHRLICH HP, 1969, ANN SURG, V170, P203, DOI 10.1097/00000658-196908000-00007
   Eppley BL, 2004, PLAST RECONSTR SURG, V114, P1502, DOI 10.1097/01.PRS.0000138251.07040.51
   Faintuch J, 2004, OBES SURG, V14, P175, DOI 10.1381/096089204322857528
   Fan JC, 2004, PLAST RECONSTR SURG, V114, P484, DOI 10.1097/01.PRS.0000132672.66547.B9
   Feuth M, 2008, LEPROSY REV, V79, P254
   FIELD CK, 1994, AM J SURG, V167, pS2, DOI 10.1016/0002-9610(94)90002-7
   Friedman HIF, 2006, PLAST RECONSTR SURG, V117, p175S, DOI 10.1097/01.prs.0000222555.84962.86
   Furie B, 2008, NEW ENGL J MED, V359, P938, DOI 10.1056/NEJMra0801082
   Gasteyger C, 2008, AM J CLIN NUTR, V87, P1128, DOI 10.1093/ajcn/87.5.1128
   GOLDBERG HM, 1981, AM J SURG, V141, P358, DOI 10.1016/0002-9610(81)90196-3
   Goldin A, 2006, CIRCULATION, V114, P597, DOI 10.1161/CIRCULATIONAHA.106.621854
   Gonyon DL Jr, 2003, ANN PLAS SURG, V50, P315, DOI 10.1097/01.SAP.0000046788.45508.A3
   GROTENDORST GR, 1989, J CELL PHYSIOL, V139, P617, DOI 10.1002/jcp.1041390323
   Gu Qingyang, 1998, Journal of Environmental Pathology Toxicology and Oncology, V17, P117
   HABEL DW, 1965, ARCHIV OTOLARYNGOL, V82, P382
   Han SK, 2006, INT J RADIAT BIOL, V82, P686, DOI 10.1080/09553000600930699
   HART GB, 1976, CANCER-AM CANCER SOC, V37, P2580, DOI 10.1002/1097-0142(197606)37:6<2580::AID-CNCR2820370603>3.0.CO;2-H
   Hess C T, 2000, Adv Skin Wound Care, V13, P63
   Hess C T, 2000, Adv Skin Wound Care, V13, P42
   Holstein P, 2004, DIABETES-METAB RES, V20, pS37, DOI 10.1002/dmrr.452
   Huijberts MSP, 2008, DIABETES-METAB RES, V24, pS19, DOI 10.1002/dmrr.861
   HUTCHINSON JJ, 1991, J HOSP INFECT, V17, P83, DOI 10.1016/0195-6701(91)90172-5
   Jones Vanessa J, 2006, Int Wound J, V3, P79, DOI 10.1111/j.1742-4801.2006.00215.x
   Khoo D B, 1992, Ann Acad Med Singap, V21, P217
   Kirkland KB, 1999, INFECT CONT HOSP EP, V20, P725, DOI 10.1086/501572
   KNIGHTON DR, 1986, ANN SURG, V204, P322, DOI 10.1097/00000658-198609000-00011
   KOLB BA, 1992, OBSTET GYNECOL, V79, P988
   KURKINEN M, 1980, LAB INVEST, V43, P47
   Ladin D, 2000, PLAST RECONSTR SURG, V105, P1230, DOI 10.1097/00006534-200003000-00065
   LAWRENCE JC, 1994, AM J SURG, V167, pS21, DOI 10.1016/0002-9610(94)90006-X
   LAWRENCE WT, 1986, SURGERY, V100, P9
   Lee Larisse K, 2008, Adv Surg, V42, P193, DOI 10.1016/j.yasu.2008.03.014
   Lee LF, 2008, PLAST RECONSTR SURG, V121, P1256, DOI 10.1097/01.prs.0000304237.54236.66
   LEIBOVICH SJ, 1975, AM J PATHOL, V78, P71
   LEVENSON SM, 1965, ANN SURG, V161, P293, DOI 10.1097/00000658-196502000-00019
   Leventhal D, 2006, ARCH FACIAL PLAST S, V8, P362, DOI 10.1001/archfaci.8.6.362
   MADDEN J W, 1970, Surgery Gynecology and Obstetrics, V130, P487
   Man D, 2001, PLAST RECONSTR SURG, V107, P229, DOI 10.1097/00006534-200101000-00037
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Marston WA, 2006, OSTOMY WOUND MANAG, V52, P26
   Martin P, 1997, SCIENCE, V276, P75, DOI 10.1126/science.276.5309.75
   Matsumine H, 2008, PLAST RECONSTR SURG, V122, P782, DOI 10.1097/PRS.0b013e318180ed43
   Mehta S, 2008, J ORTHOP TRAUMA, V22, P433, DOI 10.1097/BOT.0b013e31817e793f
   Meric F, 2000, J CLIN ONCOL, V18, P3378, DOI 10.1200/JCO.2000.18.19.3378
   MILLER SH, 1990, CLIN PLAST SURG, V17, P503
   Milovanova TN, 2008, MOL CELL BIOL, V28, P6248, DOI 10.1128/MCB.00795-08
   Moiemen NS, 2006, PLAST RECONSTR SURG, V117, p160S, DOI 10.1097/01.prs.0000222609.40461.68
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   MOUNSEY RA, 1993, LARYNGOSCOPE, V103, P605
   Payne WG, 2003, AM SURGEON, V69, P994
   Petry JJ, 1996, PLAST RECONSTR SURG, V97, P233, DOI 10.1097/00006534-199601000-00039
   POHLMAN TH, 1986, J IMMUNOL, V136, P4548
   Rees RS, 1999, WOUND REPAIR REGEN, V7, P141, DOI 10.1046/j.1524-475X.1999.00141.x
   REGAN MC, 1991, J SURG RES, V50, P442, DOI 10.1016/0022-4804(91)90022-E
   Rigotti G, 2007, PLAST RECONSTR SURG, V119, P1409, DOI 10.1097/01.prs.0000256047.47909.71
   RUDOLPH R, 1982, ANN PLAS SURG, V9, P282, DOI 10.1097/00000637-198210000-00003
   RUDOLPH R, 1977, SURG GYNECOL OBSTET, V145, P389
   Rundhaug JE, 2005, J CELL MOL MED, V9, P267, DOI 10.1111/j.1582-4934.2005.tb00355.x
   Sabolinski ML, 1996, BIOMATERIALS, V17, P311, DOI 10.1016/0142-9612(96)85569-4
   SASSLER AM, 1995, ARCH OTOLARYNGOL, V121, P162
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Shamberger R C, 1981, Int Adv Surg Oncol, V4, P15
   Smack DP, 1996, JAMA-J AM MED ASSOC, V276, P972, DOI 10.1001/jama.276.12.972
   Smiell JM, 1999, WOUND REPAIR REGEN, V7, P335, DOI 10.1046/j.1524-475X.1999.00335.x
   Telgenhoff D, 2007, WOUND REPAIR REGEN, V15, P727, DOI 10.1111/j.1524-475X.2007.00279.x
   Thomas S, 2000, J Wound Care, V9, P56
   Thomas S, 2000, J Wound Care, V9, P163
   Thomas S, 2000, J Wound Care, V9, P115
   Tibbles PM, 1996, NEW ENGL J MED, V334, P1642, DOI 10.1056/NEJM199606203342506
   Tibbs MK, 1997, RADIOTHER ONCOL, V42, P99, DOI 10.1016/S0167-8140(96)01880-4
   TOKAREK R, 1994, CLIN DERMATOL, V12, P57, DOI 10.1016/0738-081X(94)90257-7
   van Amerongen MJ, 2007, AM J PATHOL, V170, P818, DOI 10.2353/ajpath.2007.060547
   Van Beek AL, 2007, PLAST RECONSTR SURG, V119, P217, DOI 10.1097/01.prs.0000244860.00674.57
   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
   Wilensky JS, 2005, ANN PLAS SURG, V54, P297, DOI 10.1097/01.sap.0000147173.67172.2a
   YANCEY P, 1997, GIFT PAIN WHY WE HUR, pR10
   Zieker D, 2008, LANGENBECK ARCH SURG, V393, P297, DOI 10.1007/s00423-008-0286-6
NR 106
TC 63
Z9 84
U1 0
U2 21
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JUN
PY 2010
VL 125
IS 6
BP 230E
EP 244E
DI 10.1097/PRS.0b013e3181d9a0d1
PG 15
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 605XC
UT WOS:000278380700051
PM 20517064
DA 2026-07-24
ER

PT J
AU Bakri, K
   Moran, SL
AF Bakri, Karim
   Moran, Steven L.
TI Initial assessment and management of complex forearm defects
SO HAND CLINICS
LA English
DT Article
ID FREE-TISSUE TRANSFER; MUTILATING HAND INJURIES; VACUUM-ASSISTED CLOSURE;
   UPPER-EXTREMITY; FREE-FLAP; BACTERIAL INOCULATION; INTEROSSEOUS
   MEMBRANE; RECONSTRUCTION; BONE; LIMB
AB Complex trauma to the forearm often involves significant damage to or loss of bone, muscle, skin, tendons, and neurovascular structures. Treatment focuses on regaining long-term hand function, which is best achieved by combining plastic and orthopedic surgical expertise in a team that includes experienced upper arm rehabilitation therapists. The reconstruction goal is to restore a level of hand function that allows the patient to incorporate the injured hand back into daily activities. We define complex defects as those involving significant segmental loss of one or more tissue types. This article provides a framework by which these often formidable and overwhelming injuries can be approached, and discusses some of the surgical options used to reconstruct complex defects of the forearm.
C1 Mayo Clin & Mayo Fdn, Div Plast Surg, Rochester, MN 55905 USA.
C3 Mayo Clinic
RP Moran, SL (通讯作者)，Mayo Clin & Mayo Fdn, Div Plast Surg, 200 1st St SW,W 12 Mayo, Rochester, MN 55905 USA.
EM moran.steven@mayo.edu
CR Adani R, 2003, MICROSURG, V23, P32, DOI 10.1002/micr.10086
   AFEKENSTAM F, 1985, SCAND J PLAST RECONS, V19, P17
   Anglen J O, 2001, J Am Acad Orthop Surg, V9, P219
   Anglen JO, 2005, J BONE JOINT SURG AM, V87A, P1415, DOI 10.2106/JBJS.D.02615
   Anglen JO, 2003, INT ORTHOP, V27, P40
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   BAKER CC, 1986, ANN EMERG MED, V15, P1389, DOI 10.1016/S0196-0644(86)80921-0
   Bishop A, 2005, Green's operative hand surgery, P1777
   Blaisdell FW, 2002, CARDIOVASC SURG, V10, P620, DOI 10.1016/S0967-2109(02)00070-4
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   BREIDENBACH WC, 1995, PLAST RECONSTR SURG, V95, P860, DOI 10.1097/00006534-199595050-00015
   Brown RE, 2003, HAND CLIN, V19, P73, DOI 10.1016/S0749-0712(02)00143-9
   Bueno RA Jr, 2003, HAND CLIN, V19, P193, DOI 10.1016/S0749-0712(02)00142-7
   Burd T, 1999, Am J Orthop (Belle Mead NJ), V28, P156
   CALDERON W, 1986, PLAST RECONSTR SURG, V77, P785, DOI 10.1097/00006534-198605000-00016
   CHANG N, 1982, PLAST RECONSTR SURG, V70, P1
   CHAUHAN C, 1995, INJURY, V26, P415, DOI 10.1016/0020-1383(95)00036-9
   Chen HC, 2004, MICROSURG, V24, P270, DOI 10.1002/micr.20019
   CHEN SHT, 1992, PLAST RECONSTR SURG, V89, P882, DOI 10.1097/00006534-199205000-00016
   COONEY WP, 1982, J TRAUMA, V22, P112, DOI 10.1097/00005373-198202000-00006
   Derderian CA, 2003, J RECONSTR MICROSURG, V19, P455
   DIRSCHL DR, 1991, ORTHOP CLIN N AM, V22, P419
   Fitzgerald R H Jr, 1977, J Hand Surg Am, V2, P85
   FOUCHER G, 1984, BRIT J PLAST SURG, V37, P139, DOI 10.1016/0007-1226(84)90001-8
   Garrett A, 2006, AM J OTOLARYNG, V27, P29, DOI 10.1016/j.amjoto.2005.07.003
   Gedebou T M, 2002, Handchir Mikrochir Plast Chir, V34, P239, DOI 10.1055/s-2002-36290
   Georgescu AV, 2003, MICROSURG, V23, P217, DOI 10.1002/micr.10127
   Germann G, 1999, PLAST RECONSTR SURG, V103, P1386, DOI 10.1097/00006534-199904050-00007
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   GOSAIN A, 1990, PLAST RECONSTR SURG, V86, P1152, DOI 10.1097/00006534-199012000-00019
   Gupta, 1995, J Am Acad Orthop Surg, V3, P226
   Gusenoff JA, 2006, PLAST RECONSTR SURG, V118, P671, DOI 10.1097/01.prs.0000233203.84078.6b
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   GUSTILO RB, 1979, ARCH SURG-CHICAGO, V114, P805
   HAN CS, 1992, J BONE JOINT SURG AM, V74A, P1441, DOI 10.2106/00004623-199274100-00002
   Haugstvedt JR, 2002, J HAND SURG-AM, V27A, P61, DOI 10.1053/jhsu.2002.30912
   Hoffman RD, 2003, HAND CLIN, V19, P33, DOI 10.1016/S0749-0712(02)00055-0
   Holtom Paul D, 2006, J Am Acad Orthop Surg, V14, pS98
   Huerta-Alardín AL, 2005, CRIT CARE, V9, P158, DOI 10.1186/cc2978
   Hui KCW, 1999, ANN PLAS SURG, V42, P132, DOI 10.1097/00000637-199902000-00004
   Ikuta Y., 1995, Annals Academy of Medicine Singapore, V24, P124
   Innocenti M, 2005, MICROSURG, V25, P284, DOI 10.1002/micr.20130
   Jupiter JB, 1997, J BONE JOINT SURG AM, V79A, P542, DOI 10.2106/00004623-199704000-00009
   Kaufman Matthew R, 2005, Tech Hand Up Extrem Surg, V9, P47, DOI 10.1097/01.bth.0000154479.20226.22
   Kaufmann RA, 2002, J HAND SURG-AM, V27A, P93, DOI 10.1053/jhsu.2002.30072
   Khouri RK, 1998, PLAST RECONSTR SURG, V102, P711, DOI 10.1097/00006534-199809030-00015
   Kimura N, 1996, PLAST RECONSTR SURG, V97, P985, DOI 10.1097/00006534-199604001-00016
   Kremer T, 2006, PLAST RECONSTR SURG, V118, P443, DOI 10.1097/01.prs.0000227742.66799.74
   Levin LS, 2001, HAND CLIN, V17, P447
   Lin CH, 1999, PLAST RECONSTR SURG, V104, P984, DOI 10.1097/00006534-199909040-00013
   LISTER G, 1988, J HAND SURG-AM, V13A, P22, DOI 10.1016/0363-5023(88)90193-1
   Liu J, 1997, PLAST RECONSTR SURG, V99, P270, DOI 10.1097/00006534-199701000-00063
   Malizos KN, 2004, J AM ACAD ORTHOP SUR, V12, P360, DOI 10.5435/00124635-200409000-00010
   McAuliffe JA, 1999, HAND CLIN, V15, P187
   McKee D M, 1978, Clin Plast Surg, V5, P283
   McKee MD, 1996, J BONE JOINT SURG BR, V78B, P413, DOI 10.1302/0301-620X.78B3.0780413
   Moran SL, 2003, HAND CLIN, V19, P17, DOI 10.1016/S0749-0712(02)00130-0
   Moran SL, 2006, J HAND SURG-AM, V31A, P1201, DOI 10.1016/j.jhsa.2006.03.017
   Murray Peter M, 2005, Tech Hand Up Extrem Surg, V9, P29, DOI 10.1097/01.bth.0000155366.84141.ae
   Murray PM, 2004, HAND CLIN, V20, P203, DOI 10.1016/j.hcl.2004.03.005
   Neumeister MW, 2003, HAND CLIN, V19, P1, DOI 10.1016/S0749-0712(02)00141-5
   NINKOVIC M, 1995, J HAND SURG-BRIT EUR, V20B, P53, DOI 10.1016/S0266-7681(05)80017-8
   PARRY SW, 1988, PLAST RECONSTR SURG, V81, P358, DOI 10.1097/00006534-198803000-00007
   PATZAKIS MJ, 1989, CLIN ORTHOP RELAT R, P36
   PETERSON CA, 1995, J HAND SURG-AM, V20A, P609, DOI 10.1016/S0363-5023(05)80277-1
   Rajacic N, 2002, ANN PLAS SURG, V48, P252, DOI 10.1097/00000637-200203000-00004
   Reber PU, 1999, J TRAUMA, V47, P72, DOI 10.1097/00005373-199907000-00017
   ROSENSTEIN BD, 1989, J BONE JOINT SURG AM, V71A, P427, DOI 10.2106/00004623-198971030-00019
   SCHUIND F, 1991, J HAND SURG-AM, V16A, P1106, DOI 10.1016/S0363-5023(10)80075-9
   Sharma HK, 2004, INJURY, V35, P530, DOI 10.1016/S0020-1383(02)00175-4
   Stevanovic M, 1999, HAND CLIN, V15, P299
   Strauch B., 2006, Atlas of microvascular surgery: anatomy and operative techniques
   Stuart PR, 2000, J HAND SURG-AM, V25A, P689, DOI 10.1053/jhsu.2000.9418
   Sundine M, 1996, J HAND SURG-BRIT EUR, V21B, P216, DOI 10.1016/S0266-7681(96)80102-1
   Tarbox BB, 1998, CLIN ORTHOP RELAT R, P255
   TAYLOR GI, 1975, PLAST RECONSTR SURG, V55, P533, DOI 10.1097/00006534-197505000-00002
   Thomas WO, 1998, ANN PLAS SURG, V40, P23, DOI 10.1097/00000637-199801000-00005
   Urken ML, 2001, ARCH OTOLARYNGOL, V127, P862
   Wang HT, 2005, J HAND SURG-AM, V30A, P859, DOI 10.1016/j.jhsa.2005.03.016
   Watanabe H, 2005, J HAND SURG-AM, V30A, P1164, DOI 10.1016/j.jhsa.2005.06.013
   Watanabe H, 2004, J HAND SURG-AM, V29A, P1114, DOI 10.1016/j.jhsa.2004.06.005
   Wei FC, 2002, PLAST RECONSTR SURG, V109, P2219, DOI 10.1097/00006534-200206000-00007
   WILKINS J, 1991, ORTHOP CLIN N AM, V22, P433
   WOOD MB, 1987, J HAND SURG-AM, V12A, P422, DOI 10.1016/S0363-5023(87)80017-5
   Wood MB, 1997, HAND CLIN, V13, P231
   Wu WC, 1997, BRIT J PLAST SURG, V50, P73, DOI 10.1016/S0007-1226(97)91317-5
   Yajima H, 1996, PLAST RECONSTR SURG, V98, P328, DOI 10.1097/00006534-199608000-00019
   Yazar S, 2004, PLAST RECONSTR SURG, V114, P1457, DOI 10.1097/01.PRS.0000138811.88807.65
   YOUDAS JW, 1988, J ORTHOP RES, V6, P621, DOI 10.1002/jor.1100060502
   Zalavras CG, 2005, INFECT DIS CLIN N AM, V19, P915, DOI 10.1016/j.idc.2005.08.001
NR 90
TC 10
Z9 11
U1 0
U2 0
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0749-0712
EI 1558-1969
J9 HAND CLIN
JI Hand Clin.
PD MAY
PY 2007
VL 23
IS 2
BP 255
EP +
DI 10.1016/j.hcl.2007.01.003
PG 15
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 182XF
UT WOS:000247536600012
PM 17548016
DA 2026-07-24
ER

PT J
AU Ebeid, I
   Ebeid, A
   Shalaby, A
   Noureldeen, IM
   Essa, A
   Elmenawi, KA
AF Ebeid, Ibrahim
   Ebeid, Ahmed
   Shalaby, Ahmed
   Mohamed Noureldeen, Ibrahim
   Essa, Ali
   A. Elmenawi, Khaled
TI Negative pressure wound therapy for the prevention of surgical site
   infections in orthopedic and trauma surgery: a systematic review and
   meta-analysis of RCTs
SO JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY
LA English
DT Review
DE Orthopedics; Surgical site infections (SSIs); Negative pressure wound
   therapy (NPWT); Meta-analysis
ID KNEE ARTHROPLASTY; PRIMARY HIP; DRESSINGS; COMPLICATIONS; DEHISCENCE;
   FRACTURES; INCISIONS
AB BackgroundSurgical site infections (SSIs) are an important postoperative complication in orthopedic surgery, resulting in increased morbidity, prolonged hospital stay, and higher healthcare costs. Negative pressure wound therapy (NPWT) has been proposed to reduce SSIs by facilitating wound healing by increased perfusion, edema reduction, and bacterial control. This systematic review and meta-analysis evaluate the effectiveness of NPWT compared with conventional dressings for prevention of surgical site infections in orthopedic and trauma surgery.MethodsA comprehensive literature search was performed across PubMed, Web of Science, Scopus, and the Cochrane Library in December 2024. Only randomized controlled trials (RCTs) comparing NPWT with CD in patients undergoing joint replacement, trauma surgery, or spine surgery were included. Two independent reviewers conducted data extraction and assessed study quality using the Cochrane Risk of Bias 2 tool. Pooled outcomes were evaluated with odds ratios (ORs) computed for dichotomous variables and mean differences (MDs) for continuous outcomes. Heterogeneity was assessed via the I2 statistic and publication bias through Egger's test.ResultsOverall, 18 RCTs, comprising a total of 4585 patients, were included. Meta-analysis demonstrated that NPWT significantly reduced SSIs (pooled OR 0.64, 95% CI 0.50-0.82; p = 0.0005) and wound dehiscence (pooled OR 0.39, 95% CI 0.23-0.65; p = 0.0003). Additionally, NPWT was associated with a reduction in length of hospital stay by 0.87 days (MD -0.87, 95% CI -1.36 to -0.38; p = 0.0005) and fewer dressing changes compared with conventional methods. The quality of evidence for the primary outcome was rated as moderate based on the GRADE approach.ConclusionsNPWT appears to offer a significant clinical benefit in reducing the incidence of SSIs in orthopedic and trauma surgery. Secondary analyses also demonstrated benefits for surgical wound dehiscence, length of hospital stay, and number of dressing changes. However, the certainty of evidence is moderate, and these findings should be interpreted with caution. Further well-designed, multicenter RCTs are warranted to confirm these benefits, assess long-term outcomes, and evaluate cost-effectiveness.Level of evidence Level I.Registration: CRD42024624188.ConclusionsNPWT appears to offer a significant clinical benefit in reducing the incidence of SSIs in orthopedic and trauma surgery. Secondary analyses also demonstrated benefits for surgical wound dehiscence, length of hospital stay, and number of dressing changes. However, the certainty of evidence is moderate, and these findings should be interpreted with caution. Further well-designed, multicenter RCTs are warranted to confirm these benefits, assess long-term outcomes, and evaluate cost-effectiveness.Level of evidence Level I.Registration: CRD42024624188.ConclusionsNPWT appears to offer a significant clinical benefit in reducing the incidence of SSIs in orthopedic and trauma surgery. Secondary analyses also demonstrated benefits for surgical wound dehiscence, length of hospital stay, and number of dressing changes. However, the certainty of evidence is moderate, and these findings should be interpreted with caution. Further well-designed, multicenter RCTs are warranted to confirm these benefits, assess long-term outcomes, and evaluate cost-effectiveness.Level of evidence Level I.Registration: CRD42024624188.
C1 [Ebeid, Ibrahim; Ebeid, Ahmed; Shalaby, Ahmed; Mohamed Noureldeen, Ibrahim; Essa, Ali] Menoufia Univ, Fac Med, Shibin Al Kawm, Egypt.
   [A. Elmenawi, Khaled] Cleveland Clin, Dept Orthopaed Surg, Cleveland Hts, OH USA.
C3 Egyptian Knowledge Bank (EKB); Menofia University; Cleveland Clinic
   Foundation
RP Ebeid, I (通讯作者)，Menoufia Univ, Fac Med, Shibin Al Kawm, Egypt.
EM IbrahimEbeid@outlook.com
RI Ebeid, Ibrahim/PHO-6101-2026
OI Ebeid, Ibrahim/0009-0002-4264-7518
FU Minufiya University
FX Open access funding provided by The Science, Technology & Innovation
   Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank
   (EKB).
CR Adams L, 2025, J AM PODIAT MED ASSN, V115, DOI [10.7547/21-238, 10.7547/21-238]
   Adeyemi A, 2019, J ORTHOP SURG RES, V14, DOI 10.1186/s13018-019-1224-8
   Ailaney N, 2021, J ARTHROPLASTY, V36, P2402, DOI 10.1016/j.arth.2020.11.039
   Al-Mulhim FA, 2014, INT SURG, V99, P264, DOI 10.9738/INTSURG-D-13-00251.1
   Aljuhani WS, 2023, J ORTHOP SURG RES, V18, DOI 10.1186/s13018-023-04210-9
   Arti H, 2016, PAK J MED SCI, V32, P65, DOI 10.12669/pjms.321.8568
   Bai YB, 2019, MEDICINE, V98, DOI [10.1097/MD.0000000000014547, 10.1097/md.0000000000014547]
   Bhat A.K., 2018, CAN J INFECT CONTROL, V33, P227
   Bobkiewicz A, 2024, POL J MICROBIOL, V73, P199, DOI 10.33073/pjm-2024-018
   Borys S, 2019, EUR J CLIN INVEST, V49, DOI 10.1111/eci.13067
   Breznicky Jozef, 2020, Med Glas (Zenica), V17, P92, DOI [10.17392/1046-20, 10.17392/1046-20]
   Cai LY, 2022, INJURY, V53, P777, DOI 10.1016/j.injury.2021.10.018
   Canton Gianluca, 2020, Acta Biomed, V91, pe2020006, DOI 10.23750/abm.v91i14-S.10784
   cdc.gov, Surgical Site Infections (SSIs
   Collaboration TC, 2020, Review Manager (RevMan)
   Cooper HJ, 2022, J ARTHROPLASTY, V37, pS931, DOI 10.1016/j.arth.2022.03.039
   Costa ML, 2020, HEALTH TECHNOL ASSES, V24, pI, DOI 10.3310/hta24380
   Costa ML, 2018, HEALTH TECHNOL ASSES, V22, P1, DOI 10.3310/hta22730
   Crist BD, 2017, INJURY, V48, P1518, DOI 10.1016/j.injury.2017.04.055
   Edmiston CE Jr, 2023, SURG INFECT, V24, P366, DOI 10.1089/sur.2022.376
   Edmiston CE Jr, 2023, INFECT CONT HOSP EP, V44, P1587, DOI 10.1017/ice.2023.10
   Egger M, 1997, BMJ-BRIT MED J, V315, P629, DOI 10.1136/bmj.315.7109.629
   Feng YF, 2022, MEDICINE, V101, DOI 10.1097/MD.0000000000032429
   Giannini S, 2018, J WOUND CARE, V27, P520, DOI 10.12968/jowc.2018.27.8.520
   Gillespie BM, 2021, INT J SURG, V95, DOI 10.1016/j.ijsu.2021.106136
   Gillespie BM, 2015, SURG INNOV, V22, P488, DOI 10.1177/1553350615573583
   Grant-Freemantle MC, 2020, J ORTHOP TRAUMA, V34, P223, DOI 10.1097/BOT.0000000000001750
   Higuera-Rueda CA, 2021, J ARTHROPLASTY, V36, pS295, DOI 10.1016/j.arth.2021.02.076
   Hou YF, 2023, SURG OPEN SCI, V11, P1, DOI 10.1016/j.sopen.2022.10.004
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Iheozor-Ejiofor Z, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD012522.pub2
   Ingargiola Michael J, 2013, Eplasty, V13, pe49
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Keeney JA, 2019, J ARTHROPLASTY, V34, P723, DOI 10.1016/j.arth.2018.12.008
   Kim JH, 2020, INT WOUND J, V17, P1310, DOI 10.1111/iwj.13393
   Kocur Ewelina, 2021, Przegl Epidemiol, V75, P332, DOI [10.32394/pe.75.30, 10.32394/pe.75.30]
   Liu X, 2018, INT J SURG, V53, P72, DOI 10.1016/j.ijsu.2018.02.064
   Liu X, 2025, ADV SCI, V12, DOI 10.1002/advs.202408077
   Manoharan V, 2016, J ARTHROPLASTY, V31, P2487, DOI 10.1016/j.arth.2016.04.016
   Masters J, 2021, BONE JOINT J, V103B, P755, DOI 10.1302/0301-620X.103B4.BJJ-2020-1603.R1
   McFarland AM, 2023, BRIT J SURG, V110, P942, DOI 10.1093/bjs/znad144
   Meng JH, 2020, J ORTHOP SURG RES, V15, DOI 10.1186/s13018-020-01972-4
   Mengistu DA, 2023, INQUIRY-J HEALTH CAR, V60, DOI 10.1177/00469580231162549
   Mohan N, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.39465
   Mosleh S, 2021, INT J ORTHOP TRAUMA, V43, DOI 10.1016/j.ijotn.2020.100842
   Newman JM, 2019, J ARTHROPLASTY, V34, P554, DOI 10.1016/j.arth.2018.11.017
   nice.org.uk, PICO negative pressure wound dressings for closed surgical incisions
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Ouzzani M, 2016, SYST REV-LONDON, V5, DOI 10.1186/s13643-016-0384-4
   Panula VJ, 2021, ACTA ORTHOP, V92, P665, DOI 10.1080/17453674.2021.1944529
   Pappalardo Vincenzo, 2019, Surg Technol Int, V34, P56
   Pérez-Acevedo G, 2024, INT WOUND J, V21, DOI 10.1111/iwj.70034
   Qian H, 2022, FOOT ANKLE SURG, V28, P1120, DOI 10.1016/j.fas.2022.03.012
   Ren SW, 2025, J ORTHOP SURG RES, V20, DOI 10.1186/s13018-025-05463-2
   Rosen RD., 2023, Wound dehiscence
   Rucinski K, 2022, ORTHOP J SPORTS MED, V10, DOI 10.1177/23259671221084701
   Sandy-Hodgetts K, 2016, J WOUND CARE, V25, P377, DOI 10.12968/jowc.2016.25.7.377
   Sandy-Hodgetts Kylie, 2015, JBI Database System Rev Implement Rep, V13, P253, DOI [10.11124/jbisrir-2015-1687, 10.11124/jbisrir-2015-1687]
   Sandy-Hodgetts K, 2015, INT WOUND J, V12, P265, DOI 10.1111/iwj.12088
   Seidelman JL, 2023, JAMA-J AM MED ASSOC, V329, P244, DOI 10.1001/jama.2022.24075
   Silverman Ronald P, 2023, Eplasty, V23, pe54
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Tai DBG, 2022, CLIN MICROBIOL INFEC, V28, P255, DOI 10.1016/j.cmi.2021.06.006
   Virani Siddharth R, 2016, J Clin Orthop Trauma, V7, P256, DOI 10.1016/j.jcot.2016.05.007
   Wan X, 2014, BMC MED RES METHODOL, V14, DOI 10.1186/1471-2288-14-135
   Wang C, 2019, J ORTHOP SURG RES, V14, DOI 10.1186/s13018-019-1488-z
   WHO Guidelines Approved by the Guidelines Review Committee, 2018, Global Guidelines for the Prevention of Surgical Site Infection
   Yuan S, 2023, INT WOUND J, V20, P2334, DOI 10.1111/iwj.14043
   Zaver V., 2023, Negative Pressure Wound Therapy
NR 69
TC 2
Z9 2
U1 1
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1590-9921
EI 1590-9999
J9 J ORTHOP TRAUMATOL
JI J. Orthop. Traumatol.
PD DEC
PY 2025
VL 26
IS 1
AR 75
DI 10.1186/s10195-025-00889-0
PG 17
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA X7323
UT WOS:001640902300002
PM 41400731
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Yang, D
   Davies, A
   Burge, B
   Watkins, P
   Dissanaike, S
AF Yang, Derek
   Davies, April
   Burge, Bailey
   Watkins, Phillip
   Dissanaike, Sharmila
TI Open-to-Air Is a Viable Option for Initial Wound Care in Necrotizing
   Soft Tissue Infection that Allows Early Detection of Recurrence without
   Need for Painful Dressing Changes or Return to Operating Room
SO SURGICAL INFECTIONS
LA English
DT Article
DE necrotizing fasciitis; necrotizing soft tissue infection; open wound
ID STRESS
AB Background: The standard treatment of necrotizing soft tissue infection (NSTI) includes extensive surgical debridement. Care of these debridements is challenging because of the size of the wound and associated pain. A potential solution is to leave the wounds open-to-air in the period after the initial debridement, allowing for regular inspection at bedside while reducing pain associated with frequent dressing changes. We evaluated the feasibility of this approach from a pain control standpoint. Patients and Methods: An audit of wound care modalities used on adult patients with NSTI admitted to a regional burn center between January 2009 and May 2014 was performed. Patients with at least one operation were included. Those opting for palliative care were excluded. Wound care was divided into four categories: open-to-air (OTA), negative-pressure wound therapy (NPWT), packing, and ointment. Wound care, pain score, pain medication use, and number of operations were collected for the first seven days after initial debridement. Pain management was assessed by pain scores. Analgesic use was measured and compared using conversion to morphine milligram equivalents (MME). Results: Ninety-six patients were included; 67% were men with average age of 50 years, resulting in a total of 672 days of wound care evaluated: 69 days of OTA, 127 days of NPWT, 200 days of packing, and 126 days of ointment (150 days were undocumented). Average daily pain score from all wound care modalities was 2.00. Negative pressure wound therapy had the highest reported daily pain score (2.18, p=0.034), whereas OTA had the lowest pain score (1.63, p<0.05). Mortality was lower in the OTA cohort but was not statistically significant; there were no other differences in long-term outcome. Conclusion: Leaving wounds OTA is a safe and viable option in the immediate post-debridement period of NSTI to reduce pain, while permitting frequent re-evaluation for quick recognition of disease progression and repeat operative debridement if necessary.
C1 [Yang, Derek; Dissanaike, Sharmila] Texas Tech Univ, Hlth Sci Ctr, Sch Med, Dept Surg, Lubbock, TX 79430 USA.
   [Davies, April; Burge, Bailey] Univ Med Ctr, Lubbock, TX USA.
   [Watkins, Phillip] Texas Tech Univ, Hlth Sci Ctr, Clin Res Inst, Lubbock, TX 79430 USA.
C3 Texas Tech University System; Texas Tech University Health Sciences
   Center; Texas Tech University System; Texas Tech University Health
   Sciences Center; Texas Tech University System; Texas Tech University
   Health Sciences Center
RP Dissanaike, S (通讯作者)，3601 4th St STOP 8312, Lubbock, TX 79430 USA.
EM sharmila.dissanaike@ttuhsc.edu
CR Anaya DA, 2007, CLIN INFECT DIS, V44, P705, DOI 10.1086/511638
   Ebrecht M, 2004, PSYCHONEUROENDOCRINO, V29, P798, DOI 10.1016/S0306-4530(03)00144-6
   Eggerstedt M, 2015, J BURN CARE RES, V36, P105, DOI 10.1097/BCR.0000000000000203
   Janssen AH, 2016, J WOUND CARE, V25, P9
   Kane SP, 2017, OPIOID OPIATE EQUIAN
   McGuire L, 2006, ANN BEHAV MED, V31, P165, DOI 10.1207/s15324796abm3102_8
   MCHENRY CR, 1995, ANN SURG, V221, P558, DOI 10.1097/00000658-199505000-00013
   Myers BA, 2011, WOUND MANAGEMENT PRI
   Ousey K, 2014, HEALTHCARE-BASEL, V2, P346, DOI 10.3390/healthcare2030346
   Solowiej K, 2010, J WOUND CARE, V19, P153, DOI 10.12968/jowc.2010.19.4.153
   Stevens DL, 2014, CLIN INFECT DIS, V59, pE10, DOI [10.1093/cid/ciu296, 10.1093/cid/ciu444]
   SUDARSKY LA, 1987, ANN SURG, V206, P661
   Upton D, 2013, J WOUND CARE, V22, P91
   Upton D, 2015, INT WOUND J, V12, P100, DOI 10.1111/iwj.12059
   Ustin JS, 2011, CRIT CARE MED, V39, P2156, DOI 10.1097/CCM.0b013e31821cb246
   Vijayakumar A, 2014, ISRN INFECT DIS, V2014, P208072, DOI 10.1155/2014/208072
   Woo KY, 2008, ADV SKIN WOUND CARE, V21, P90
NR 17
TC 5
Z9 5
U1 0
U2 2
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD JAN
PY 2018
VL 19
IS 1
BP 65
EP 70
DI 10.1089/sur.2017.080
EA DEC 2017
PG 6
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA FR9JV
UT WOS:000417296800001
PM 29211657
DA 2026-07-24
ER

PT J
AU Pellino, G
   Sciaudone, G
   Candilio, G
   De Fatico, GS
   Landino, I
   Della Corte, A
   Guerniero, R
   Benevento, R
   Santoriello, A
   Campitiello, F
   Selvaggi, F
   Canonico, S
AF Pellino, Gianluca
   Sciaudone, Guido
   Candilio, Giuseppe
   De Fatico, G. Serena
   Landino, Isabella
   Della Corte, Angela
   Guerniero, Raffaella
   Benevento, Raffaella
   Santoriello, Antonio
   Campitiello, Ferdinando
   Selvaggi, Francesco
   Canonico, Silvestro
TI Preventive NPWT over closed incisions in general surgery: Does age
   matter?
SO INTERNATIONAL JOURNAL OF SURGERY
LA English
DT Article
DE Negative pressure wound therapy; Colorectal surgery; Breast; Surgical
   site infection; Surgical site event; SSI; Complication
ID SURGICAL SITE INFECTION; POUCH-ANAL ANASTOMOSIS; ULCERATIVE-COLITIS;
   CROHNS-DISEASE; RESTORATIVE PROCTOCOLECTOMY; ILEAL POUCH; STAPLED
   HAEMORRHOIDOPEXY; ANTIBIOTIC-PROPHYLAXIS; COLORECTAL SURGERY;
   RANDOMIZED-TRIAL
AB Surgical site events (SSE), including surgical wound complications and surgical site infections, are a major concern in patients undergoing general surgery operations. These increase the costs of care, and can lead to prolonged hospital stay and need for further treatments, ultimately resulting in poor quality of life. Negative pressure wound therapy (NPWT) has been recently reported as a preventive strategy to avoid SSE, but little is known on the topic, and particularly in geriatric population.
   Our primary aim was to assess the efficacy of NPWT by means of a pocket device (PICO, Smith & Nephew, London, UK) in preventing SSE compared with conventional dressings in patients undergoing surgery with primary wound closure for breast and for colorectal diseases in our Unit. Our secondary aims were to assess the efficacy and safety of PICO in elderly patients, and to seek for differences between breast and abdominal results.
   All consecutive patients undergoing breast and colorectal surgery in our Unit between September 2012 and May 2014 were prospectively enrolled in this open label controlled study. Breast patients receiving NPWT were assigned to group B1, those receiving conventional dressings were assigned to group B2. Colorectal patients were assigned to group C1 (NPWT) and C2 (conventional dressings) in similar fashion. Each group included 25 patients, and at least 10 (40%) patients aged over 65 years to allow sub-analyses.
   NPWT significantly reduced SSE in both breast and colorectal patients compared with controls. No significant differences were observed according to age. Similar benefits were observed in breast and colorectal patients.
   Our results suggest that PICO is an effective tool to prevent SSE in patients undergoing general surgery, irrespective of age. Its use is recommended in frail, elderly patients at risk of SSE. (C) 2014 Published by Elsevier Ltd on behalf of Surgical Associates Ltd.
C1 [Pellino, Gianluca; Sciaudone, Guido; Candilio, Giuseppe; De Fatico, G. Serena; Landino, Isabella; Della Corte, Angela; Guerniero, Raffaella; Benevento, Raffaella; Santoriello, Antonio; Campitiello, Ferdinando; Selvaggi, Francesco; Canonico, Silvestro] Univ Naples 2, Dept Med Surg Neurol Metab & Ageing Sci, I-80138 Naples, Italy.
C3 Universita della Campania Vanvitelli
RP Canonico, S (通讯作者)，Univ Naples 2, Dept Med Surg Neurol Metab & Ageing Sci, Piazza Miraglia 2, I-80138 Naples, Italy.
EM gipe1984@gmail.com; guido.sciaudone@unina2.it; g.candilio@alice.it;
   seredefa@gmail.com; isabella.landino@fastwebnet.it;
   angeladellacorte@live.it; raffaella.guerniero@libero.it;
   raffaella.benevento@gmail.com; antonio.santoriello@unina2.it;
   ferdinando.campitiello@unina2.it; fselvaggi@hotmail.com;
   silvestro.canonico@unina2.it
RI Selvaggi, Francesco/HSH-7500-2023; Pellino, Gianluca/B-8458-2015
OI Selvaggi, Francesco/0000-0002-3219-3797; Pellino,
   Gianluca/0000-0002-8322-6421; SCIAUDONE, Guido/0000-0003-4221-8502
CR Accardo G, 2014, MINERVA CHIR S1, V69, P97
   [Anonymous], J CROHNS COLITIS
   Anthony T, 2011, ARCH SURG-CHICAGO, V146, P263, DOI 10.1001/archsurg.2010.249
   Benevento R, 2012, BMC SURG, V12, DOI 10.1186/1471-2482-12-S1-S6
   Borgquist O., 2010, WOUNDS INT, V1, P1
   Canani RB, 2003, GASTROENTEROLOGY, V124, P368, DOI 10.1053/gast.2003.50056
   Canonico S, 2013, SURGERY, V153, P126, DOI 10.1016/j.surg.2012.06.024
   Cima R, 2013, J AM COLL SURGEONS, V216, P23, DOI 10.1016/j.jamcollsurg.2012.09.009
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   Egan L, 2014, J CROHNS COLITIS, V8, P19, DOI 10.1016/j.crohns.2013.04.009
   Gagliardi G, 2010, TECH COLOPROCTOL, V14, P229, DOI 10.1007/s10151-010-0597-9
   Hedrick TL, 2013, DIS COLON RECTUM, V56, P627, DOI 10.1097/DCR.0b013e318279a93e
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Muller-Lissner SA, 1998, Z GASTROENTEROL, V36, P273
   Musto D, 2010, ENDOSCOPY, V42, pE299, DOI 10.1055/s-0030-1255788
   Pasquale P, 2010, HEPATO-GASTROENTEROL, V57, P482
   Pellino G, 2014, INT J SURG, V12, pS156, DOI 10.1016/j.ijsu.2014.05.022
   Pellino G, 2014, SURG INNOV, V21, P204, DOI 10.1177/1553350613496906
   Pellino G, 2014, GASTROENT RES PRACT, V2014, DOI 10.1155/2014/340341
   Pellino G, 2013, BMC SURG, V13, DOI 10.1186/1471-2482-13-S2-S57
   Pellino G, 2013, BMC SURG, V13, DOI 10.1186/1471-2482-13-S2-S9
   Pellino G, 2013, HEPATOB PANCREAT DIS, V12, P136, DOI 10.1016/S1499-3872(13)60022-3
   Pellino G, 2013, INFLAMM BOWEL DIS, V19, pE16, DOI 10.1002/ibd.22847
   Pellino G, 2012, BMC SURG, V12, DOI 10.1186/1471-2482-12-S1-S31
   Pellino G, 2012, WORLD J GASTROENTERO, V18, P1703, DOI 10.3748/wjg.v18.i15.1703
   Petronella P, 2012, ANN ITAL CHIR, V83, P297
   Reilly J, 2001, J HOSP INFECT, V49, P245, DOI 10.1053/jhin.2001.1086
   Romano M, 2007, DIS COLON RECTUM, V50, P650, DOI 10.1007/s10350-006-0807-8
   Sanguinetti A, 2009, ANN ITAL CHIR, V80, P275
   Sciaudone G, 2011, EUR SURG RES, V46, P163, DOI 10.1159/000324398
   Sciaudone G, 2011, J GASTROEN HEPATOL, V26, P610, DOI 10.1111/j.1440-1746.2011.06622.x
   Sciaudone G, 2010, PANMINERVA MED, V52, P91
   Sciaudone G, 2010, ACTA CHIR BELG, V110, P213, DOI 10.1080/00015458.2010.11680601
   Sciaudone G, 2008, TECH COLOPROCTOL, V12, P61, DOI 10.1007/s10151-008-0389-z
   Sciaudone G, 2011, INFLAMM BOWEL DIS, V17, pE28, DOI 10.1002/ibd.21642
   Sciaudone G, 2011, J CROHNS COLITIS, V5, P60, DOI 10.1016/j.crohns.2010.08.003
   Sciaudone G, 2010, CAN J SURG, V53, P299
   Secondulfo M, 2004, Minerva Gastroenterol Dietol, V50, P155
   Selvaggi F, 2007, INFLAMM BOWEL DIS, V13, P641, DOI 10.1002/ibd.20056
   Selvaggi F, 2005, GASTROEN CLIN BIOL, V29, P939, DOI 10.1016/S0399-8320(05)86462-0
   Selvaggi F, 2003, Colorectal Dis, V5, P496, DOI 10.1046/j.1463-1318.2003.00517.x
   Selvaggi F, 2014, TECH COLOPROCTOL, V18, P847, DOI 10.1007/s10151-014-1180-6
   Selvaggi F, 2012, TECH COLOPROCTOL, V16, P415, DOI 10.1007/s10151-012-0838-1
   Selvaggi F, 2010, COLORECTAL DIS, V12, pE172, DOI 10.1111/j.1463-1318.2009.02003.x
   Selvaggi F, 2000, DIS COLON RECTUM, V43, P615, DOI 10.1007/BF02235573
   Selvaggi F, 2014, MINERVA CHIR S1, V69, P105
   Selvaggi F, 2006, INT J COLORECTAL DIS, V21, P448, DOI 10.1007/s00384-005-0036-y
   Selvaggi Francesco, 2004, Chir Ital, V56, P239
   Selvaggi F, 2014, INFLAMM BOWEL DIS, V20, P1296, DOI 10.1097/MIB.0000000000000026
   Selvaggi Francesco, 2014, Surg Technol Int, V24, P83
   Selvaggi F, 2010, J CUTAN PATHOL, V37, P1182, DOI 10.1111/j.1600-0560.2009.01395.x
   Selvaggi F, 2010, AM SURGEON, V76, P428
   Stulberg JJ, 2010, JAMA-J AM MED ASSOC, V303, P2479, DOI 10.1001/jama.2010.841
   WILSON APR, 1986, LANCET, V1, P311
NR 54
TC 60
Z9 67
U1 0
U2 8
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1743-9191
EI 1743-9159
J9 INT J SURG
JI Int. J. Surg.
PD OCT
PY 2014
VL 12
SU 2
BP S64
EP S68
DI 10.1016/j.ijsu.2014.08.378
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CR0ER
UT WOS:000360991700017
PM 25159226
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Wang, B
   Cheng, W
   Liu, FN
   Guo, ZH
   Ji, ZJ
   Sun, KM
   Yao, MY
AF Wang, Biao
   Cheng, Weyland
   Liu, Fangna
   Guo, Zhanhao
   Ji, Zejuan
   Sun, Keming
   Yao, Manye
TI Efficacy and safety of vancomycin-loaded calcium sulfate versus
   conventional surgical debridement for pediatric acute osteomyelitis: a
   retrospective study
SO BMC MUSCULOSKELETAL DISORDERS
LA English
DT Article
DE vancomycin; Localized antibiotic delivery; Acute hematogenous
   osteomyelitis; Negative-pressure wound therapy; Parenteral therapy
ID ACUTE HEMATOGENOUS OSTEOMYELITIS; BONE-CEMENT; CHILDREN
AB Background: The purpose of this study was to evaluate the safety and efficacy of vancomycin-loaded calcium sulfate beads and negative-pressure wound therapy (NPWT) in treating children with acute hematogenous osteomyelitis (AHOM). Methods: A retrospective cohort study was conducted from January 2017 to January 2020 examining children (n = 60) with AHOM who were treated with surgical debridement followed by vancomycin-loaded calcium sulfate beads and NPWT (n = 32) and compared to treatment by conventional surgical debridement (n = 28) followed by NPWT. Conventional surgical treatment consisted of fenestration of necrotic infected bone, debridement of surrounding soft tissue, and washing of the medullary canal before the application of NPWT. In the vancomycin group, the antibiotic-loaded beads were implanted after washing the medullary canal and before the application of NPWT. Epidemiological factors, complications during the procedure, outcomes at last follow-up (30.0 & PLUSMN; 11.7 months, range 13-58 months), and laboratory parameters were documented and compared between the two groups. Results: Good outcomes were achieved at last follow-up in 71.4% of the conventional treatment group and 75% of the vancomycin group. In the vancomycin group, it took a mean of 4.8 & PLUSMN; 2.5 days for CRP levels to decrease to 50% of initial inflammatory levels compared to 13 & PLUSMN; 9.6 days for the conventional treatment group (p = 0.001, t-test). The conventional group also had seven patients who underwent four or more surgeries whereas no patients in the vancomycin group underwent more than three surgeries (p = 0.013, chi-square test). Conclusion: Localized vancomycin delivery with NPWT effective for treating cases of AHOM that required. No perioperative adverse reactions or complications occurred from this treatment method. Based on the shortened recovery period of CRP levels, prolonged administration of post-operational parenteral antibiotics can possibly be reduced with this treatment method.
C1 [Wang, Biao; Cheng, Weyland; Liu, Fangna; Guo, Zhanhao; Ji, Zejuan; Sun, Keming; Yao, Manye] Zhengzhou Univ, Dept Orthopaed Surg, Henan Childrens Hosp, Zhengzhou Childrens Hosp,Childrens Hosp, 33 Longhu Waihuan East Rd, Zhengzhou 450018, Henan, Peoples R China.
   [Cheng, Weyland] Zhengzhou Univ, Henan Prov Key Lab Childrens Genet & Metab Dis, Henan Childrens Hosp, Zhengzhou Childrens Hosp,Childrens Hosp, 33 Longhu Waihuan East Rd, Zhengzhou 450018, Henan, Peoples R China.
C3 Zhengzhou University; Zhengzhou University
RP Cheng, W; Sun, KM; Yao, MY (通讯作者)，Zhengzhou Univ, Dept Orthopaed Surg, Henan Childrens Hosp, Zhengzhou Childrens Hosp,Childrens Hosp, 33 Longhu Waihuan East Rd, Zhengzhou 450018, Henan, Peoples R China.; Cheng, W (通讯作者)，Zhengzhou Univ, Henan Prov Key Lab Childrens Genet & Metab Dis, Henan Childrens Hosp, Zhengzhou Childrens Hosp,Childrens Hosp, 33 Longhu Waihuan East Rd, Zhengzhou 450018, Henan, Peoples R China.
EM wey_c@hotmail.com; sunkeming@126.com; ymy19641@126.com
OI Cheng, Weyland/0000-0002-1846-2946
FU Henan Provincial Medical Science and Technology Research Plan Joint
   Construction Project;  [LHGJ20210667]
FX This work was supported by the Henan Provincial Medical Science and
   Tech-nology Research Plan Joint Construction Project (LHGJ20210667).
CR Andreacchio A, 2019, J PEDIATR ORTHOP B, V28, P189, DOI 10.1097/BPB.0000000000000517
   Grimbly C, 2013, SYST REV, V2, DOI 10.1186/2046-4053-2-92
   Howlin RP, 2015, ANTIMICROB AGENTS CH, V59, P111, DOI 10.1128/AAC.03676-14
   Jiang N, 2020, ACTA ORTHOP, V91, P353, DOI 10.1080/17453674.2020.1745423
   Li JF, 2019, MED SCI MONITOR, V25, P5343, DOI 10.12659/MSM.915921
   Liu X, 2016, MED SCI MONITOR, V22, P1959, DOI 10.12659/MSM.896108
   McNeil JC, 2020, INFECT DRUG RESIST, V13, P4459, DOI 10.2147/IDR.S257517
   Qin CH, 2019, BMC MUSCULOSKEL DIS, V20, DOI 10.1186/s12891-019-2635-8
   Rajnish RK, 2019, J PEDIATR ORTHOP B, V28, P415, DOI 10.1097/BPB.0000000000000630
   Ruebner R, 2006, PEDIATRICS, V117, P1210, DOI 10.1542/peds.2005-1465
   Saavedra-Lozano J, 2017, PEDIATR INFECT DIS J, V36, P788, DOI 10.1097/INF.0000000000001635
   Shi XW, 2022, J ORTHOP SURG RES, V17, DOI 10.1186/s13018-022-02980-2
   Thakolkaran N, 2019, OCHSNER J, V19, P116, DOI 10.31486/toj.18.0138
   Wheeler AM, 2012, J PEDIATR INFECT DIS, V1, P152, DOI [10.1093/jpids/pis035, 10.1093/JPIDS/PIS035]
   Xiong G, 2021, N Am Spine Soc J, V5
   Zhang ZQ, 2018, J ORTHOP SURG RES, V13, DOI 10.1186/s13018-018-0916-9
NR 16
TC 9
Z9 11
U1 2
U2 6
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2474
J9 BMC MUSCULOSKEL DIS
JI BMC Musculoskelet. Disord.
PD DEC 23
PY 2022
VL 23
IS 1
AR 1124
DI 10.1186/s12891-022-06105-y
PG 8
WC Orthopedics; Rheumatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Rheumatology
GA 7H8MX
UT WOS:000903452800001
PM 36564738
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Acosta, S
   Wanhainen, A
   Björck, M
AF Acosta, S.
   Wanhainen, A.
   Bjorck, M.
TI Temporary Abdominal Closure After Abdominal Aortic Aneurysm Repair: A
   Systematic Review of Contemporary Observational Studies
SO EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
LA English
DT Review
DE Temporary abdominal closure; Open abdomen; Aortic aneurysm; Negative
   pressure wound therapy
ID ASSISTED WOUND CLOSURE; MEDIATED FASCIAL TRACTION; REINFORCED TENSION
   LINE; OPEN ABDOMEN TREATMENT; COMPARTMENT SYNDROME; INTRAABDOMINAL
   HYPERTENSION; ENDOVASCULAR REPAIR; VACUUM; MANAGEMENT; METAANALYSIS
AB Objectives: The aim of this paper was to review the literature on temporary abdominal closure (TAC) after abdominal aortic aneurysm (AAA) repair.
   Methods: This was a systematic review of observational studies. A PubMed, EM BASE and Cochrane search from 2007 to July 2015 was performed combining the Medical Subject Headings "aortic aneurysm" and "temporary abdominal closure", "delayed abdominal closure", "open abdomen", "abdominal compartment syndrome", "negative pressure wound therapy", or "vacuum assisted wound closure".
   Results: Seven original studies were found. The methods used for TAC were the vacuum pack system with (n = 1) or without (n = 2) mesh bridge, vacuum assisted wound closure (VAWC; n = 1) and the VAWC with mesh mediated fascial traction (VACM; n = 3). The number of patients included varied from four to 30. Three studies were exclusively after open repair, one after endovascular aneurysm repair, and three were mixed series. The frequency of ruptured AAA varied from 60% to 100%. The primary fascia] closure rate varied from 79% to 100%. The median time to closure of the open abdomen was 10.5 and 17 days in two prospective studies with a fascia] closure rate of 100% and 96%, respectively; the inclusion criterion was an anticipated open abdomen therapy time >= 5 days using the VACM method. The graft infection rate was 0% in three studies. No patient with longterm open abdomen therapy with the VACM in the three studies was left with a planned ventral hernia. The in hospital survival rate varied from 46% to 80%.
   Conclusions: A high fascial closure rate without planned ventral hernia is possible to achieve with VACM, even after long-term open abdomen therapy. There are, however, few publications reporting specific results of open abdomen treatment after AAA repair, and there is a need for randomized controlled trials to determine the most efficient and safe TAC method during open abdomen treatment after AAA repair. (C) 2015 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
C1 [Acosta, S.] Lund Univ, Vasc Ctr, Dept Clin Sci, Malmo, Sweden.
   [Wanhainen, A.; Bjorck, M.] Uppsala Univ, Dept Surg Sci, Vasc Surg, Uppsala, Sweden.
C3 Lund University; Uppsala University
RP Acosta, S (通讯作者)，Skane Univ Hosp, Vasc Ctr Malmo, S-20502 Malmo, Sweden.
EM stefan.acosta@telia.com
RI Acosta, Stefan/JAX-3225-2023
OI Acosta, Stefan/0000-0002-3225-0798
CR Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
   Agarwal A, 2011, TROP DOCT, V41, P193, DOI 10.1258/td.2011.110045
   Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
   Bahia SS, 2015, EUR J VASC ENDOVASC, V50, P320, DOI 10.1016/j.ejvs.2015.05.004
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Björck M, 2014, EUR J VASC ENDOVASC, V47, P279, DOI 10.1016/j.ejvs.2013.12.014
   Björck M, 2012, SEMIN VASC SURG, V25, P35, DOI 10.1053/j.semvascsurg.2012.03.002
   Björck M, 2009, WORLD J SURG, V33, P1154, DOI 10.1007/s00268-009-9996-3
   Cheatham ML, 2013, WORLD J SURG, V37, P2018, DOI 10.1007/s00268-013-2080-z
   Cheatham ML, 2010, CRIT CARE MED, V38, P402, DOI 10.1097/CCM.0b013e3181b9e9b1
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   Frazee RC, 2013, J AM COLL SURGEONS, V216, P730, DOI 10.1016/j.jamcollsurg.2012.12.035
   Hollinsky C, 2007, AM J SURG, V194, P234, DOI 10.1016/j.amjsurg.2006.09.045
   Karkos CD, 2014, J VASC SURG, V59, P829, DOI 10.1016/j.jvs.2013.11.085
   Kimball EJ, 2009, VASCULAR, V17, P309, DOI 10.2310/6670.2009.00048
   Kirkendall A, 2015, AM J HOSP PALLIAT ME, V32, P313, DOI 10.1177/1049909114526969
   Kirkpatrick AW, 2013, INTENS CARE MED, V39, P1190, DOI 10.1007/s00134-013-2906-z
   Mayer D, 2009, J VASC SURG, V50, P1, DOI 10.1016/j.jvs.2008.12.030
   Mukhi AN, 2014, CAN J SURG, V57, P314, DOI 10.1503/cjs.026613
   Muysoms FE, 2015, HERNIA, V19, P1, DOI 10.1007/s10029-014-1342-5
   Petersson U, 2007, WORLD J SURG, V31, P2133, DOI 10.1007/s00268-007-9222-0
   Pommerening MJ, 2014, SURGERY, V156, P431, DOI 10.1016/j.surg.2014.04.019
   Rasilainen S, 2015, SCAND J SURG
   Rasilainen SK, 2012, BRIT J SURG, V99, P1725, DOI 10.1002/bjs.8914
   Roberts DJ, 2012, J TRAUMA ACUTE CARE, V73, P629, DOI 10.1097/TA.0b013e31825c130e
   Ross CB, 2009, AM SURGEON, V75, P565
   Rubenstein C, 2015, J VASC SURG, V61, P648, DOI 10.1016/j.jvs.2014.10.011
   Sammons A, 2009, CLIN S ADV SKIN WOUN
   Seternes A, 2010, EUR J VASC ENDOVASC, V40, P60, DOI 10.1016/j.ejvs.2010.02.018
   Sörelius K, 2013, EUR J VASC ENDOVASC, V45, P588, DOI 10.1016/j.ejvs.2013.01.041
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   Willms A, 2015, LANGENBECK ARCH SURG, V400, P91, DOI 10.1007/s00423-014-1240-4
NR 33
TC 24
Z9 27
U1 0
U2 7
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 1078-5884
EI 1532-2165
J9 EUR J VASC ENDOVASC
JI Eur. J. Vasc. Endovasc. Surg.
PD MAR
PY 2016
VL 51
IS 3
BP 371
EP 378
DI 10.1016/j.ejvs.2015.10.014
PG 8
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA DH3LZ
UT WOS:000372689800010
PM 26652956
OA Bronze
DA 2026-07-24
ER

PT J
AU Achten, J
   Parsons, NR
   Bruce, J
   Petrou, S
   Tutton, E
   Willett, K
   Lamb, SE
   Costa, ML
AF Achten, Juul
   Parsons, Nick R.
   Bruce, Julie
   Petrou, Stavros
   Tutton, Elizabeth
   Willett, Keith
   Lamb, Sarah E.
   Costa, Matthew L.
TI Protocol for a randomised controlled trial of standard wound management
   versus negative pressure wound therapy in the treatment of adult
   patients with an open fracture of the lower limb: UK Wound management of
   Open Lower Limb Fractures (UK WOLFF)
SO BMJ OPEN
LA English
DT Article
ID ASSISTED CLOSURE THERAPY; HEALTH; INFECTION; EUROQOL; COSTS
AB Introduction: Patients who sustain open lower limb fractures have reported infection risks as high as 27%. The type of dressing applied after initial debridement could potentially affect this risk. In this trial, standard dressings will be compared with a new emerging treatment, negative pressure wound therapy, for patients with open lower limb fractures.
   Methods and analysis: All adult patients presenting with an open lower limb fracture, with a Gustilo and Anderson (G&A) grade 2/3, will be considered for inclusion. 460 consented patients will provide 90% power to detect a difference of eight points in the Disability Rating Index (DRI) score at 12 months, at the 5% level. A randomisation sequence, stratified by trial centre and G&A grade, will be produced and administered by a secure web-based service. A qualitative substudy will assess patients' experience of giving consent for the trial, and acceptability of trial procedures to patients and staff. Patients will have clinical follow-up in a fracture clinic up to a minimum of 12 months as per standard National Health Service (NHS) practice. Functional and quality of life outcome data will be collected using the DRI, SF12 and EQ-5D questionnaires at 3, 6, 9 and 12 months postoperatively. In addition, information will be requested with regards to resource use and any late complications or surgical interventions related to their injury. The main analysis will investigate differences in the DRI score at 1 year after injury, between the two treatment groups on an intention-to-treat basis. Tests will be two sided and considered to provide evidence for a significant difference if p values are less than 0.05.
   Ethics and dissemination: Ethical approval was given by NRES Committee West Midlands-Coventry & Warwickshire on 6/2/2012 (ref: 12/WM/0001). The results of the trial will be disseminated via peer-reviewed publications and presentations at relevant conferences.
C1 [Achten, Juul; Parsons, Nick R.; Bruce, Julie; Petrou, Stavros; Costa, Matthew L.] Univ Warwick, Warwick Med Sch, Coventry CV4 7AL, W Midlands, England.
   [Tutton, Elizabeth; Willett, Keith; Lamb, Sarah E.] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford, England.
C3 University of Warwick; University of Oxford
RP Achten, J (通讯作者)，Univ Warwick, Warwick Med Sch, Coventry CV4 7AL, W Midlands, England.
EM Juul.Achten@ndorms.ox.ac.uk
RI Petrou, Stavros/ABD-8323-2021; Achten, Juul/KUD-8515-2024; Parsons,
   Nick/AAA-8713-2019; Bruce, Julie/G-7588-2014
OI Petrou, Stavros/0000-0003-3121-6050; Achten, Juul/0000-0002-8857-5743;
   Parsons, Nick/0000-0001-9975-888X; Bruce, Julie/0000-0002-8462-7999;
   Lamb, Sarah/0000-0003-4349-7195; Costa, Matthew/0000-0003-3644-1388;
   Tutton, Elizabeth/0000-0003-3973-360X
FU Health Technology Assessment Programme of the National Institute of
   Health Research (NIHR) [HTA10/57/20]; NIHR Oxford Musculoskeletal
   Biomedical Research Unit; University of Warwick; University Hospitals
   Coventry and Warwickshire NHS trust; MRC [G0700452, G0501681] Funding
   Source: UKRI; Economic and Social Research Council [1499410] Funding
   Source: researchfish; Medical Research Council [G0700452, G0501681]
   Funding Source: researchfish; National Institute for Health Research
   [10/57/20] Funding Source: researchfish
FX This trial is funded through the Health Technology Assessment Programme
   of the National Institute of Health Research (NIHR; HTA10/57/20). The
   research was supported by the NIHR Oxford Musculoskeletal Biomedical
   Research Unit. The views expressed are those of the author(s) and not
   necessarily those of the NHS, the NIHR or the Department of Health. This
   protocol was written following the SPIRIT protocol guidance. The trial
   was co-sponsored by the University of Warwick and University Hospitals
   Coventry and Warwickshire NHS trust.
CR Allen C., 1993, COSTING COMMUNITY CA, P25
   [Anonymous], 2013, Guide to the Methods of Technology Appraisal
   Apelqvist J, 2008, AM J SURG, V195, P782, DOI 10.1016/j.amjsurg.2007.06.023
   Barbour Rose., 2007, Doing Focus Groups, The Sage Qualitative Research Kit
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   Brazier J, 2002, J HEALTH ECON, V21, P271, DOI 10.1016/S0167-6296(01)00130-8
   Brooks R, 1996, HEALTH POLICY, V37, P53, DOI 10.1016/0168-8510(96)00822-6
   Court-Brown CM, 1998, INJURY, V29, P529, DOI 10.1016/S0020-1383(98)00125-9
   Dolan P, 1997, MED CARE, V35, P1095, DOI 10.1097/00005650-199711000-00002
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Horan TC, 2008, AM J INFECT CONTROL, V36, P309, DOI 10.1016/j.ajic.2008.03.002
   Labler L, 2009, J TRAUMA, V66, P749, DOI 10.1097/TA.0b013e318171971a
   Louie KW, 2009, BMJ-BRIT MED J, V339, DOI 10.1136/bmj.b5092
   MacKenzie EJ, 2007, J BONE JOINT SURG AM, V89A, P1685, DOI 10.2106/JBJS.F.01350
   Mason J., 2002, QUALITATIVE RES ACTI, P225, DOI [10.4135/9781849209656.n10, DOI 10.4135/9781849209656.N10]
   Miles MB., 2014, Qualitative data analysis: An expanded sourcebook, VThird
   Mody RM, J TRAUMA
   Pollak AN, 2008, J ORTHOP TRAUMA, V22, pS142, DOI 10.1097/BOT.0b013e318188e2a9
   Pollak AN, 2010, J BONE JOINT SURG AM, V92A, P7, DOI 10.2106/JBJS.H.00984
   Runkel N, 2011, INJURY, V42, pS1, DOI 10.1016/S0020-1383(11)00041-6
   SALEN BA, 1994, J CLIN EPIDEMIOL, V47, P1423, DOI 10.1016/0895-4356(94)90086-8
   Sculpher MJ, 2006, HEALTH ECON, V15, P677, DOI 10.1002/hec.1093
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   van den Brink M, 2000, 16 ANN M INT SOC HLT
   Varadhan R, 2010, MED CARE, V48, pS96, DOI 10.1097/MLR.0b013e3181d99107
   Ware J.E., 2005, Health Assessment Lab
NR 26
TC 17
Z9 22
U1 0
U2 4
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 2044-6055
J9 BMJ OPEN
JI BMJ Open
PY 2015
VL 5
IS 9
AR e009087
DI 10.1136/bmjopen-2015-009087
PG 10
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA CU4FZ
UT WOS:000363484000087
PM 26395498
OA Green Accepted, gold
DA 2026-07-24
ER

PT J
AU Hohendorff, J
   Drozdz, A
   Borys, S
   Ludwig-Slomczynska, AH
   Kiec-Wilk, B
   Stepien, EL
   Malecki, MT
AF Hohendorff, Jerzy
   Drozdz, Anna
   Borys, Sebastian
   Ludwig-Slomczynska, Agnieszka H.
   Kiec-Wilk, Beata
   Stepien, Ewa L.
   Malecki, Maciej T.
TI Effects of Negative Pressure Wound Therapy on Levels of Angiopoetin-2
   and Other Selected Circulating Signaling Molecules in Patients with
   Diabetic Foot Ulcer
SO JOURNAL OF DIABETES RESEARCH
LA English
DT Article
ID ANGIOPOIETIN-2; MICROPARTICLES; CELLS; MICROVESICLES; VESICLES;
   AMPUTATION; SURVIVAL; ENHANCE; GROWTH; VEGF
AB Background and Aims. Diabetic foot ulcers (DFUs) are linked to amputations and premature deaths. Negative pressure wound therapy (NPWT) has been used for DFUs. The mechanism of NPWT's action may be associated with its influence on circulating molecules. We assessed NPWT's effect on the plasma levels of angiopoietin-2 (Ang2), a key regulator of angiogenesis, and its microvesicular receptors (Tie2) as well as the microvesicles (MVs) themselves in DFU patients. Materials and Methods. We included 69 patients with type 2 diabetes mellitus (T2DM) and neuropathic, noninfected DFUs-49 were treated with NPWT and 20 were treated with standard therapy (ST). Assigning patients to the NPWT group was not random but based on DFU characteristics, especially wound area. Ang2 was measured by ELISA in the entire group, while in a subgroup of 19 individuals on NPWT and 10 on ST, flow cytometry was used to measure Tie2+ and the corresponding isotype control (Iso+) and annexin V (AnnV+) as well as total MVs. Measurements were performed at the beginning and after 8 +/- 1 days of therapy. Results. Treatment groups were similar for basic characteristics but differed by their median DFU areas (10.3 (4.2-18.9) vs. 1.3 (0.9-3.4) cm(2), p=0.0001). At day 0, no difference was observed in Ang2 levels, total MVs, MV Tie+, and MV AnnV+ between the groups. Ang2 decreased after 8 days in the NPWT group, unlike in the ST group (3.54 (2.40-5.40) vs. 3.32 (2.33-4.61), p=0.02, and 3.19 +/- 1.11 vs. 3.19 +/- 1.29 ng/mL, p=0.98, respectively). No other parameters were identified that may have been influenced by the NPWT treatment. Conclusion. NPWT in T2DM patients with neuropathic, noninfected DFU seems to lead to reduction of the Ang2 level. Influencing the level of Ang2 may constitute one of NPWT-related mechanisms to accelerate wound healing.
C1 [Hohendorff, Jerzy; Borys, Sebastian; Kiec-Wilk, Beata; Malecki, Maciej T.] Jagiellonian Univ, Dept Metab Dis, Med Coll, Krakow, Poland.
   [Hohendorff, Jerzy; Borys, Sebastian; Kiec-Wilk, Beata; Malecki, Maciej T.] Univ Hosp, Clin Metab Dis, Krakow, Poland.
   [Drozdz, Anna; Stepien, Ewa L.] Jagiellonian Univ, Marian Smoluchowski Inst Phys, Dept Med Phys, Krakow, Poland.
   [Drozdz, Anna] Jagiellonian Univ, Malopolska Ctr Biotechnol, Krakow, Poland.
   [Ludwig-Slomczynska, Agnieszka H.] Jagiellonian Univ, Ctr Med Genom OMICRON, Med Coll, Krakow, Poland.
C3 Jagiellonian University; Collegium Medicum Jagiellonian University;
   Jagiellonian University; Collegium Medicum Jagiellonian University;
   Jagiellonian University; Jagiellonian University; Jagiellonian
   University; Collegium Medicum Jagiellonian University
RP Malecki, MT (通讯作者)，Jagiellonian Univ, Dept Metab Dis, Med Coll, Krakow, Poland.; Malecki, MT (通讯作者)，Univ Hosp, Clin Metab Dis, Krakow, Poland.
EM malecki_malecki@yahoo.com
RI Stepien, Ewa/H-7471-2019; Drozdz, Anna/ISB-5280-2023; Hohendorff,
   Jerzy/U-1857-2018
OI Stepien, Ewa/0000-0003-3589-1715; Drozdz, Anna/0000-0003-3999-6725;
   Hohendorff, Jerzy/0000-0003-1153-8669; Ludwig-Słomczyńska, Agnieszka
   H/0000-0002-0548-4767
FU National Science Centre in Poland [2013/11/B/NZ5/03298]
FX The study was funded by the National Science Centre in Poland through
   the Opus Grant "Assessment of Molecular Mechanisms of Negative Pressure
   Wound Therapy in the Treatment of Neuropathic Ulceration in Diabetic
   Foot Syndrome" to MTM (Nr 2013/11/B/NZ5/03298). The authors thank Mrs.
   Katherine Zerebiec for her linguistic review of the manuscript.
CR Akwii RG, 2019, CELLS-BASEL, V8, DOI 10.3390/cells8050471
   Al-Nedawi K, 2009, P NATL ACAD SCI USA, V106, P3794, DOI 10.1073/pnas.0804543106
   Alexandru N, 2017, ACTA PHYSIOL, V221, P230, DOI 10.1111/apha.12896
   Armstrong DG, 2017, NEW ENGL J MED, V376, P2367, DOI 10.1056/NEJMra1615439
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Augustin HG, 2009, NAT REV MOL CELL BIO, V10, P165, DOI 10.1038/nrm2639
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Borys S, 2019, ACTA DIABETOL, V56, P115, DOI 10.1007/s00592-018-1223-y
   Borys S, 2019, EUR J CLIN INVEST, V49, DOI 10.1111/eci.13067
   Cabral J, 2018, ADV DRUG DELIVER REV, V129, P394, DOI 10.1016/j.addr.2018.01.018
   Chen JY, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0115316
   Diamant M, 2002, CIRCULATION, V106, P2442, DOI 10.1161/01.CIR.0000036596.59665.C6
   Game FL, 2016, DIABETES-METAB RES, V32, P75, DOI 10.1002/dmrr.2700
   Georgescu A, 2012, J THROMB HAEMOST, V10, P680, DOI 10.1111/j.1538-7836.2012.04650.x
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Hoffmann M, 2015, DIABETES VASC DIS RE, V12, P265, DOI 10.1177/1479164115579005
   Kämpfer H, 2001, LAB INVEST, V81, P361, DOI 10.1038/labinvest.3780244
   Khalaf Nervana, 2017, Electron Physician, V9, P5031, DOI [10.19082/5031, 10.19082/5031]
   Li X, 2018, EXP MOL MED, V50, DOI 10.1038/s12276-018-0058-5
   Liu Y, 2018, INT J LOW EXTR WOUND, V17, P144, DOI 10.1177/1534734618794856
   Lobov IB, 2002, P NATL ACAD SCI USA, V99, P11205, DOI 10.1073/pnas.172161899
   Ludwig-Slomczynska AH, 2019, ENDOCR CONNECT, V8, P1474, DOI 10.1530/EC-19-0373
   Maisonpierre PC, 1997, SCIENCE, V277, P55, DOI 10.1126/science.277.5322.55
   Mazzieri R, 2011, CANCER CELL, V19, P512, DOI 10.1016/j.ccr.2011.02.005
   Mu SC, 2019, VASCULAR, V27, P381, DOI 10.1177/1708538119836360
   Trinh NT, 2016, BIOCHEM BIOPH RES CO, V473, P1111, DOI 10.1016/j.bbrc.2016.04.025
   Oshima Y, 2005, FASEB J, V19, P963, DOI 10.1096/fj.04-2209fje
   Oshima Y, 2004, J CELL PHYSIOL, V199, P412, DOI 10.1002/jcp.10442
   Patel JV, 2008, ANN MED, V40, P215, DOI 10.1080/07853890701779586
   Rasul S, 2011, CARDIOVASC DIABETOL, V10, DOI 10.1186/1475-2840-10-55
   Ren S, 2019, STEM CELL RES THER, V10, DOI 10.1186/s13287-019-1152-x
   Santi A, 2015, BBA-MOL CELL RES, V1853, P3211, DOI 10.1016/j.bbamcr.2015.09.013
   Schara K, 2017, EUR J PHARM SCI, V98, P58, DOI 10.1016/j.ejps.2016.09.009
   Schuldt EA, 2018, CYTOKINE, V105, P1, DOI 10.1016/j.cyto.2018.02.003
   Stepien E, 2012, ARCH MED RES, V43, P31, DOI 10.1016/j.arcmed.2012.01.006
   Stepien EL, 2018, THERANOSTICS, V8, P3874, DOI 10.7150/thno.23334
   Syrjälä SO, 2014, AM J TRANSPLANT, V14, P1096, DOI 10.1111/ajt.12672
   Thurston G, 2012, CSH PERSPECT MED, V2, DOI 10.1101/cshperspect.a006650
   Tricarico C., 2017, SMALL GTPASES, V8, P220, DOI 10.1080/21541248.2016.1215283
   Tsai YC, 2018, KIDNEY BLOOD PRESS R, V43, P545, DOI 10.1159/000488826
   Than UTT, 2017, INT J MOL SCI, V18, DOI 10.3390/ijms18050956
   Van Slyke P, 2009, TISSUE ENG PT A, V15, P1269, DOI 10.1089/ten.tea.2007.0400
   Walsh JW, 2016, DIABETIC MED, V33, P1493, DOI 10.1111/dme.13054
   Wang Y, 2019, DIABETES, V68, DOI 10.2337/db19-637-P
NR 44
TC 8
Z9 10
U1 0
U2 11
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 2314-6745
EI 2314-6753
J9 J DIABETES RES
JI J. Diabetes Res.
PD OCT 28
PY 2019
VL 2019
AR 1756798
DI 10.1155/2019/1756798
PG 7
WC Endocrinology & Metabolism; Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism; Research & Experimental Medicine
GA JN6CP
UT WOS:000496984300002
PM 31781660
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Philip, EF
   Rajandram, R
   Zuber, M
   Khong, TL
   Roslani, AC
AF Philip, Eleanor Felsy
   Rajandram, Retnagowri
   Zuber, Mariana
   Khong, Tak Loon
   Roslani, April Camilla
TI Prophylactic PICO◊ dressing shortens wound dressing
   requirements post emergency laparotomy (EL-PICO◊ trial)
SO WORLD JOURNAL OF EMERGENCY SURGERY
LA English
DT Article
DE Emergency laparotomy; Negative pressure wound therapy; PICO lozenge
   dressing; Surgical site infection
ID SURGICAL SITE INFECTIONS; THERAPY; SURGERY; INCISIONS
AB Background Surgical site infection (SSI) is a very common complication of emergency laparotomy and causes significant morbidity. The PICO lozenge device delivers negative pressure wound therapy (NPWT) to closed incisions, with some studies suggesting a role for prevention of SSI in heterogenous surgical populations. We aimed to compare SSI rates between patients receiving PICO lozenge versus conventional dressing post-emergency laparotomy. Secondary objectives were to observe seroma and dehiscence rates, length of stay, days on dressing and patients' wound experience. Methods This double blinded randomized controlled trial was conducted in University Malaya Medical Centre between October 2019 and March 2022. Patients undergoing emergency laparotomy requiring incisions less than 35 cm were included. Statistical analysis was performed using chi 2 test for categorical variables, independent T-test or Mann-Whitney U were used for parametric or non-parametric data respectively besides logistic regression. P values of < 0.05 were considered to be significant. Results Ninety-six patients were analyzed (47 interventions, 49 controls). The duration on dressing was more consistent in the intervention arm (PICO lozenge) versus control arm [9.78 +/- 10.20 vs 17.78 +/- 16.46 days, P < 0.001]. There was a trend towards lower SSI [14.3 vs 4.3%, P = 0.09], dehiscence [27.1 vs 10.6%, P = 0.07] and seroma [40.8 vs 23.4%, P = 0.08] rates in the intervention arm but this did not reach statistical significance. Length of stay [9 (IQR: 6-14) vs 11 (IQR: 6-22.5) days, P = 0.18] was fairly similar between the two arms, but more patients were very satisfied with PICO lozenge compared to the conventional dressing [80% vs 57.1%, P = 0.03]. Conclusion The use of NPWT in emergency laparotomy improves patients wound care experience, and was associated with trends towards fewer wound related complications. Cost effectiveness needs to be explored in order to further validate its use in the emergency setting, especially for patients with additional risk for SSI.<br /> Trial registration National Medical Research Registry (NMRR): NMRR-20-1975-55222.
C1 [Philip, Eleanor Felsy; Rajandram, Retnagowri; Zuber, Mariana; Khong, Tak Loon; Roslani, April Camilla] Univ Malaya, Fac Med, Dept Surg, Kuala Lumpur 50603, Malaysia.
C3 Universiti Malaya
RP Roslani, AC (通讯作者)，Univ Malaya, Fac Med, Dept Surg, Kuala Lumpur 50603, Malaysia.
EM april@ummc.edu.my
RI Rajandram, Retnagowri/E-4709-2010; Roslani, April/B-8245-2010; Khong,
   Tak/S-4746-2017
OI Rajandram, Retnagowri/0000-0001-5247-2817; 
FU University Malaya Specialist Centre (UMSC) C.A.R.E Fund; Department of
   Surgery, Faculty of Medicine, Universiti Malaya
FX The authors would like to thank colleagues from the Department of
   Surgery, Faculty of Medicine, Universiti Malaya for their support in the
   completion of this study. The authors would also like to thank Nordiana
   Mohd Hashan, Nuraini Thammili (nurses) and Nik Nadia Nik Mohd Nasir
   (study coordinator), Kartheeni Nair Achuthan (RA).
CR Abdallah DY, 2013, EUR SPINE J, V22, P2800, DOI 10.1007/s00586-013-2890-6
   Anjum N, 2017, DIS COLON RECTUM, V60, P1291, DOI [10.1097/DCR.0000000000000927, 10.1097/dcr.0000000000000927]
   [Anonymous], 2018, Perioperative Mortality Review (POMR): Prioritisation of Cases for Emergency and Elective Surgery
   Cheng KP, 2012, COLORECTAL DIS, V14, pE346, DOI 10.1111/j.1463-1318.2012.02943.x
   Groenen H, 2023, ECLINICALMEDICINE, V62, DOI 10.1016/j.eclinm.2023.102105
   Horan TC, 2008, AM J INFECT CONTROL, V36, P309, DOI 10.1016/j.ajic.2008.03.002
   Hou YF, 2023, SURG OPEN SCI, V11, P1, DOI 10.1016/j.sopen.2022.10.004
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Macefield R, 2019, BJS-BRIT J SURG, V106, P226, DOI 10.1002/bjs.11008
   Malmsjo Malin, 2014, Eplasty, V14, pe15
   Mawalla B, 2011, BMC SURG, V11, DOI 10.1186/1471-2482-11-21
   Meyer J, 2023, WORLD J SURG, V47, P1464, DOI 10.1007/s00268-023-06908-7
   Mohan N, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.39465
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Pellino G, 2014, INT J SURG, V12, pS64, DOI 10.1016/j.ijsu.2014.08.378
   Ralph N, 2020, SYST REV-LONDON, V9, DOI 10.1186/s13643-020-01293-x
   Schurtz E, 2018, AM J SURG, V215, P113, DOI 10.1016/j.amjsurg.2017.08.009
   Selvaggi Francesco, 2014, Surg Technol Int, V24, P83
   Sidhu AS, 2018, ADV UROL, V2018, DOI 10.1155/2018/8727301
   Tabiri S, 2018, WORLD J SURG, V42, P916, DOI 10.1007/s00268-017-4241-y
   Tan L, 2019, Madridge Journal of Surgery, V2, P52, DOI [10.18689/mjs-1000113, 10.18689/mjs-1000113.]
   Urbaniak G.C., 1997, Research Randomizer
   Wong K, 2019, Wounds Int Asia, V10, P13
   World Union of Wound Healing Societies (WUWHS), 2016, Consensus Document Closed surgical incision management: understanding the role of NPWTWounds
NR 26
TC 4
Z9 4
U1 0
U2 4
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-7922
J9 WORLD J EMERG SURG
JI World J. Emerg. Surg.
PD NOV 22
PY 2024
VL 19
IS 1
AR 38
DI 10.1186/s13017-024-00560-9
PG 11
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA N1Z5B
UT WOS:001362397100001
PM 39578859
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Czerny-Bednarczyk, K
   Slabon, A
   Ziolkowska, K
   Klama-Baryla, A
   Wielgorecki, A
   Gierek, M
   Strzelec, P
   Labus, W
AF Czerny-Bednarczyk, Katarzyna
   Slabon, Anna
   Ziolkowska, Karolina
   Klama-Baryla, Agnieszka
   Wielgorecki, Artur
   Gierek, Marcin
   Strzelec, Przemyslaw
   Labus, Wojciech
TI Tissue engineering as a tool in a novel approach to the comprehensive
   treatment and management of a deeply and extensively burned patient:
   case report
SO CELL AND TISSUE BANKING
LA English
DT Article
DE Severe burn wound; Human acellular dermal matrix; Human amnion graft; In
   vitro cultured keratinocytes and fibroblasts; Negative pressure wound
   therapy; Laser speckle contrast analysis; High-frequency USG
ID THICKNESS SKIN-GRAFT; AMNIOTIC MEMBRANE; DERMAL SUBSTITUTE; WOUND
   EXCISION; IN-HOUSE; THERAPY; RECONSTRUCTION; KERATINOCYTES; OUTCOMES
AB Deep and extensive thermal burns with concurrent inhalation injuries can be associated with a high mortality rate, especially among elderly patients. Injuries of this type require treatment in highly. specialized centers. Early excision and autografting are the standard of care for extensive, deep burns. To achieve a functionally and aesthetically satisfactory burn scar, allogeneic acellular dermal matrices (ADMs) can be used as co-grafts alongside autologous split-thickness skin grafts (STSGs). Additionally, the application of in vitro-cultured autologous keratinocytes and fibroblasts has been shown to accelerate burn wound healing. Allogeneic amnion transplantation can also be performed to promote healing at donor sites. This paper presents a case report of a 65 year-old patient with thermal burns covering 26% total body surface area (TBSA) with third-degree burns affecting the thorax, abdomen, back, right shoulder, right elbow, and right thigh, as well as airway involvement. The patient underwent multistage surgical treatment, including deep excision of necrotic tissues. The wound was treated using a combination of ADM, free STSG, in vitro-cultured skin cells, and local negative pressure wound therapy (NPWT). Allogeneic amnion grafts were applied to the donor sites, which were used multiple times after healing. Healing progress was monitored using laser speckle contrast analysis (LASCA). Additionally, scar viscoelasticity, transepidermal water loss, melanin content, epidermal thickness, and temperature were examined post-healing. Selected skin parameters were also assessed using high-frequency ultrasound. The patient was discharged on day 77, having spent 41 days in the surgical ward and 36 days in the rehabilitation ward, with fully healed wounds. It is important to note that rehabilitation began on the first day of hospitalization. Follow-up visits documented gradual improvement in the evaluated scar parameters.
C1 [Czerny-Bednarczyk, Katarzyna; Slabon, Anna; Ziolkowska, Karolina; Klama-Baryla, Agnieszka; Wielgorecki, Artur; Gierek, Marcin; Strzelec, Przemyslaw; Labus, Wojciech] Stanislaw Sakiel Burn Treatment Ctr Siemianowice S, Jana Pawla 2 St, PL-41100 Siemianowice Slaskie, Poland.
   [Slabon, Anna] Med Univ Silesia, Doctoral Sch, Fac Hlth Sci Bytom, PL-41902 Katowice, Bytom, Poland.
C3 Medical University of Silesia
RP Czerny-Bednarczyk, K; Labus, W (通讯作者)，Stanislaw Sakiel Burn Treatment Ctr Siemianowice S, Jana Pawla 2 St, PL-41100 Siemianowice Slaskie, Poland.
EM katarzyna.czerny@clo.com.pl; wojciech.labus@gmail.com
RI Gierek, Marcin/AAE-1727-2022; Łabuś, Wojciech/I-3141-2019
OI Czerny-Bednarczyk, Katarzyna/0009-0005-2269-3009; Łabuś,
   Wojciech/0000-0003-2108-9270; Wielgórecki, Artur/0009-0004-1063-9112
CR Alkhonizy SW, 2024, PRS-GLOB OPEN, V12, DOI 10.1097/GOX.0000000000005572
   Auxenfans C, 2015, BURNS, V41, P71, DOI 10.1016/j.burns.2014.05.019
   Ba YLG, 2025, BURNS, V51, DOI 10.1016/j.burns.2025.107415
   Bartels P, 2020, BURNS, V46, P1272, DOI 10.1016/j.burns.2020.05.003
   Boyce ST, 2023, J BURN CARE RES, V44, pS50, DOI 10.1093/jbcr/irac107
   Czajkowska J, 2023, SCI REP-UK, V13, DOI 10.1038/s41598-023-45126-y
   Davies B, 2024, BURNS, V50, P1011, DOI 10.1016/j.burns.2024.01.001
   De Decker I, 2023, BURNS TRAUMA, V11, DOI 10.1093/burnst/tkad015
   Dijkstra A, 2023, BURNS, V49, P1907, DOI 10.1016/j.burns.2023.04.009
   Elmasry M, 2019, BURNS, V45, P798, DOI 10.1016/j.burns.2019.02.001
   Eskandarlou M, 2016, WORLD J PLAST SURG, V5, P39
   Gardien KLM, 2023, ADV SKIN WOUND CARE, V36, P540, DOI 10.1097/ASW.0000000000000040
   Gierek M, 2023, J CLIN MED, V12, DOI 10.3390/jcm12062112
   Gierek M, 2022, BIOMEDICINES, V10, DOI 10.3390/biomedicines10112870
   Gierek M, 2022, BIOENGINEERING-BASEL, V9, DOI 10.3390/bioengineering9080389
   Giordano S, 2024, PLAST RECONSTR SURG, V153, P717, DOI 10.1097/PRS.0000000000010810
   Glaser J, 2021, BURNS, V47, P1259, DOI 10.1016/j.burns.2021.06.010
   Glat P, 2024, J BURN CARE RES, V45, P1287, DOI 10.1093/jbcr/irae050
   HERNDON DN, 1989, ANN SURG, V209, P547, DOI 10.1097/00000658-198905000-00006
   Hunger S, 2021, J CRANIO MAXILL SURG, V49, P403, DOI 10.1016/j.jcms.2021.02.015
   Janzekovic Z, 1970, J Trauma, V10, P1103
   Kilmer LH, 2024, PRS-GLOB OPEN, V12, DOI 10.1097/GOX.0000000000005660
   Kitala D, 2020, TRANSPL P, V52, P2563, DOI 10.1016/j.transproceed.2020.01.110
   Kitala D, 2019, ADV CLIN EXP MED, V28, P5, DOI 10.17219/acem/76327
   Kitala D, 2016, ADV CLIN EXP MED, V25, P923, DOI 10.17219/acem/61961
   Kohlhauser M, 2024, CELL MOL BIOL LETT, V29, DOI 10.1186/s11658-023-00526-w
   Krezdorn N, 2016, Ann Burns Fire Disasters, V29, P223
   Labus W, 2022, CELL TISSUE BANK, V23, P863, DOI 10.1007/s10561-022-10001-z
   Labus W, 2020, J BIOMED MATER RES B, V108, P1281, DOI 10.1002/jbm.b.34476
   Labus Wojciech, 2015, Pol Przegl Chir, V87, P513, DOI [10.1515/pjs-2015-0097, 10.1515/pjs-2015-0097]
   Labus W, 2018, J BIOMED MATER RES B, V106, P726, DOI 10.1002/jbm.b.33883
   Li TT, 2020, EXP THER MED, V20, P512, DOI 10.3892/etm.2020.8679
   Manasyan A, 2024, BURNS, V50, DOI 10.1016/j.burns.2024.107288
   Markel JE, 2024, PRS-GLOB OPEN, V12, DOI 10.1097/GOX.0000000000006174
   Matsumura H, 2016, BURNS, V42, P769, DOI 10.1016/j.burns.2016.01.019
   Mihalecko J, 2022, PHYSIOL RES, V71, pS51, DOI 10.33549/physiolres.935045
   Moghimi MH, 2024, BMC SURG, V24, DOI 10.1186/s12893-024-02554-5
   Moiemen N, 2017, European practice guidelines for burn care
   Morton CA, 2012, BRIT J DERMATOL, V167, P2, DOI 10.1111/j.1365-2133.2012.10914.x
   Moussa A, 2021, BURNS, V47, P1300, DOI 10.1016/j.burns.2020.12.014
   Noureldine AM, 2024, J FR OPHTALMOL, V47, DOI 10.1016/j.jfo.2023.04.009
   Pero M, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-22190-4
   Pirayesh A, 2015, BURNS, V41, P132, DOI 10.1016/j.burns.2014.05.013
   Polanska A, 2017, POSTEP DERM ALERGOL, V34, P535, DOI 10.5114/ada.2017.72457
   Saaiq M, 2012, Ann Burns Fire Disasters, V25, P143
   Sadeqi Hamidreza, 2024, Scars Burn Heal, V10, p20595131231218062, DOI [10.1177/20595131231218062, 10.1177/20595131231218062]
   Sadlocha M, 2024, J CLIN MED, V13, DOI 10.3390/jcm13061550
   Salemans RFC, 2024, PLOS ONE, V19, DOI 10.1371/journal.pone.0299809
   Simaey M, 2024, BURNS, V50, DOI 10.1016/j.burns.2024.08.013
   Stanton E, 2024, J BURN CARE RES, V45, P1026, DOI 10.1093/jbcr/irae014
   Suca H, 2024, J SURG RES, V296, P383, DOI 10.1016/j.jss.2023.12.043
   Usmani A, 2022, CUREUS J MED SCIENCE, V14, DOI 10.7759/cureus.26161
   Vaheb M, 2020, ADV SKIN WOUND CARE, V33, P636, DOI 10.1097/01.ASW.0000695752.52235.e3
   Vosinakis C, 2024, BURNS, V50, DOI 10.1016/j.burns.2024.10.002
   Wallner B, 2023, EUR J TRAUMA EMERG S, V49, P551, DOI 10.1007/s00068-022-02107-6
   Wong LW, 2021, BURNS, V47, P1705, DOI 10.1016/j.burns.2021.07.001
   Yin YC, 2018, INT J SURG, V50, P43, DOI 10.1016/j.ijsu.2017.12.020
   Yuan Y, 2023, FRONT SURG, V10, DOI 10.3389/fsurg.2023.1304333
NR 58
TC 1
Z9 1
U1 2
U2 2
PU SPRINGER
PI DORDRECHT
PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
SN 1389-9333
EI 1573-6814
J9 CELL TISSUE BANK
JI Cell Tissue Banking
PD NOV 24
PY 2025
VL 27
IS 1
AR 2
DI 10.1007/s10561-025-10203-1
PG 19
WC Cell Biology; Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Engineering
GA E2233
UT WOS:001622322200004
PM 41284087
DA 2026-07-24
ER

PT J
AU Kuo, FC
   Hsu, CW
   Tan, TL
   Lin, PY
   Tu, YK
   Chen, PC
AF Kuo, Feng-Chih
   Hsu, Chih-Wei
   Tan, Timothy L.
   Lin, Pao-Yen
   Tu, Yu-Kang
   Chen, Po-Cheng
TI Effectiveness of Different Wound Dressings in the Reduction of Blisters
   and Periprosthetic Joint Infection After Total Joint Arthroplasty: A
   Systematic Review and Network Meta-Analysis
SO JOURNAL OF ARTHROPLASTY
LA English
DT Review
DE wound dressings; total joint arthroplasty; blister; infection; hip; knee
ID TOTAL HIP; KNEE ARTHROPLASTY; CONTROLLED-TRIAL; THERAPY; CONSISTENCY;
   AQUACEL
AB Background: The optimal type of dressing in the setting of total joint arthroplasty (TJA) remains uncertain. The aim of this network meta-analysis was to compare various wound dressings and identify the optimal type of dressings for blister reduction and prevention of periprosthetic joint infection (PJI) in patients after TJA.
   Methods: Studies comparing 2 or more dressing groups after TJA (hip or knee) were systematically searched on PubMed, Embase, and Scopus. Two authors performed the study selection, risk of bias assessment, and data extraction. Both outcomes were assessed using odds ratios (OR) with 95% confidence intervals (CI) and were ranked using surface under the cumulative ranking curve (SUCRA) probabilities to determine a hierarchy of dressings. A sensitivity analysis was performed to reduce the effect of intransitivity between studies.
   Results: A total of 21 studies, consisting of 12 dressing types in 7293 TJAs, were included in the final analysis. The highest incidence of blisters occurred when using negative-pressure wound therapy (OR 9.33, 95% CI 3.51-24.83, vs gauze). All dressings ranked better than gauze in infection rate except for hydrofiber (OR 1.46, 95% CI 0.02-112.53) and fabric dressings (OR 1.46, 95% CI 0.24-9.02). For blister reduction, alginate (SUCRA = 87.7%) and hydrofiber with hydrocolloid (SUCRA = 92.3%) were ranked as the optimal dressings before and after a sensitivity analysis, respectively. Antimicrobial dressing (SUCRA = 83.7%) demonstrated the most efficacy for preventing PJI.
   Conclusion: Based on the evidence from our analysis, an antimicrobial dressing is the optimal dressing to prevent PJI. If negative-pressure wound therapy is used, surgeons should be aware of an increased incidence of blister formation. Further studies should focus on the alginate versus hydrofiber and hydrocolloid dressing to determine the optimal dressing to reduce blisters. (C) 2021 The Author(s). Published by Elsevier Inc.
C1 [Kuo, Feng-Chih] Chang Gung Univ, Kaohsiung Chang Gung Mem Hosp, Coll Med, Dept Orthopaed Surg, Kaohsiung, Taiwan.
   [Hsu, Chih-Wei; Lin, Pao-Yen] Chang Gung Univ, Kaohsiung Chang Gung Mem Hosp, Coll Med, Dept Psychiat, Kaohsiung, Taiwan.
   [Tan, Timothy L.] Thomas Jefferson Univ, Rothman Orthopaed Inst, Philadelphia, PA 19107 USA.
   [Lin, Pao-Yen] Kaohsiung Chang Gung Mem Hosp, Inst Translat Res Biomed Sci, Kaohsiung, Taiwan.
   [Tu, Yu-Kang] Natl Taiwan Univ, Coll Publ Hlth, Inst Epidemiol & Prevent Med, Taipei, Taiwan.
   [Chen, Po-Cheng] Chang Gung Univ, Kaohsiung Chang Gung Mem Hosp, Coll Med, Dept Phys Med & Rehabil, Kaohsiung, Taiwan.
   [Chen, Po-Cheng] Natl Cheng Kung Univ, Coll Med, Dept Publ Hlth, Tainan, Taiwan.
C3 Chang Gung University; Chang Gung Memorial Hospital; Chang Gung
   University; Chang Gung Memorial Hospital; Thomas Jefferson University;
   Rothman Institute; Chang Gung Memorial Hospital; National Taiwan
   University; Chang Gung Memorial Hospital; Chang Gung University;
   National Cheng Kung University
RP Chen, PC (通讯作者)，Kaohsiung Chang Gung Mem Hosp, Dept Phys Med & Rehabil, 123 Dapi Rd, Kaohsiung 833, Taiwan.
RI Tan, Timothy/AAK-4232-2020; Kuo, Feng-Chih/W-3327-2019; Chen,
   Po-Cheng/ABH-6133-2020; Tu, Yu-Kang/C-7303-2009
OI Kuo, Feng-Chih/0000-0001-5205-8333; Chen, Po-Cheng/0000-0002-6386-2850;
   Tu, Yu-Kang/0000-0002-2461-474X
FU Chang Gung Memorial Hospital, Taiwan [CFRPG8H0141]
FX We appreciated the Biostatistics Center of Kaohsiung Chang Gung Memorial
   Hospital for the statistics work. This work was supported by Chang Gung
   Memorial Hospital, Taiwan (grant numbers CFRPG8H0141).
CR Aboltins CA, 2019, J ARTHROPLASTY, V34, pS279, DOI 10.1016/j.arth.2018.09.012
   Abuzakuk Tarek M, 2006, Int Wound J, V3, P133, DOI 10.1111/j.1742-4801.2006.00189.x
   Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe288, DOI 10.1016/S1473-3099(16)30402-9
   Anderson DJ, 2014, INFECT CONT HOSP EP, V35, P605, DOI 10.1086/676022
   Aslam AA, 2017, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD012040.pub2
   Belden K, 2019, J ARTHROPLASTY, V34, pS387, DOI 10.1016/j.arth.2018.09.023
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Burke NG, 2012, J TISSUE VIABILITY, V21, P84, DOI 10.1016/j.jtv.2012.04.002
   Cai J, 2014, J ARTHROPLASTY, V29, P1098, DOI 10.1016/j.arth.2013.11.012
   Chaimani A, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0076654
   Clarke J V, 2009, J Wound Care, V18, P5
   Cosker T, 2005, J Wound Care, V14, P27
   Curley AJ, 2018, ORTHOPEDICS, V41, pE837, DOI 10.3928/01477447-20181010-02
   Dias S, 2010, STAT MED, V29, P932, DOI 10.1002/sim.3767
   Dobbelaere A, 2015, ACTA ORTHOP BELG, V81, P454
   Evans RP, 2009, J BONE JOINT SURG AM, V91A, P2, DOI 10.2106/JBJS.I.00549
   Gillespie BM, 2015, SURG INNOV, V22, P488, DOI 10.1177/1553350615573583
   Grosso MJ, 2017, J ARTHROPLASTY, V32, P929, DOI 10.1016/j.arth.2016.08.039
   Gupta S K, 2002, J Wound Care, V11, P271
   Harle S, 2005, INT J ORTHOP TRAUMA, V9, P205, DOI 10.1016/j.joon.2005.09.003
   Higgins JPT, 2012, RES SYNTH METHODS, V3, P98, DOI 10.1002/jrsm.1044
   HORAN TC, 1992, INFECT CONT HOSP EP, V13, P606
   Howell RD, 2011, CURR ORTHOP PRACT, V22, P176, DOI 10.1097/BCO.0b013e31820b3e21
   Hutton B, 2015, ANN INTERN MED, V162, P777, DOI 10.7326/M14-2385
   Jones SA, 2004, WOUND REPAIR REGEN, V12, P288, DOI 10.1111/j.1067-1927.2004.012304.x
   Jung WK, 2008, APPL ENVIRON MICROB, V74, P2171, DOI 10.1128/AEM.02001-07
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Keeney JA, 2019, J ARTHROPLASTY, V34, P723, DOI 10.1016/j.arth.2018.12.008
   Kim JH, 2019, J ARTHROPLASTY, V34, P2804, DOI 10.1016/j.arth.2019.06.020
   Kuo FC, 2017, BIOMED RES INT, V2017, DOI 10.1155/2017/1262108
   Langlois J, 2015, INT ORTHOP, V39, P1315, DOI 10.1007/s00264-015-2726-6
   Leaper D, 2008, BMJ-BRIT MED J, V337, DOI 10.1136/bmj.a1924
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Manoharan V, 2016, J ARTHROPLASTY, V31, P2487, DOI 10.1016/j.arth.2016.04.016
   Nherera LM, 2017, WOUND REPAIR REGEN, V25, P474, DOI 10.1111/wrr.12530
   Parvizi J, 2013, BONE JOINT J, V95B, P1450, DOI 10.1302/0301-620X.95B11.33135
   Parvizi J, 2018, J ARTHROPLASTY, V33, P1309, DOI 10.1016/j.arth.2018.02.078
   Parvizi J, 2011, CLIN ORTHOP RELAT R, V469, P2992, DOI 10.1007/s11999-011-2102-9
   Ravenscroft MJ, 2006, ANN ROY COLL SURG, V88, P18, DOI 10.1308/003588406X82989
   Ravnskog FA, 2011, J WOUND CARE, V20, P136, DOI 10.12968/jowc.2011.20.3.136
   Redfern RE, 2017, J ARTHROPLASTY, V32, P3333, DOI 10.1016/j.arth.2017.06.019
   Rosenbaum AJ, 2018, J AM ACAD ORTHOP SUR, V26, P833, DOI 10.5435/JAAOS-D-17-00024
   Salanti G, 2011, J CLIN EPIDEMIOL, V64, P163, DOI 10.1016/j.jclinepi.2010.03.016
   Sharma G, 2017, INT ORTHOP, V41, P1295, DOI 10.1007/s00264-017-3484-4
   Springer Bryan D, 2015, Am J Orthop (Belle Mead NJ), V44, P415
   Stang A, 2010, EUR J EPIDEMIOL, V25, P603, DOI 10.1007/s10654-010-9491-z
   Tisosky AJ, 2017, JAAOS GLOB RES REV, V1, DOI 10.5435/JAAOSGlobal-D-17-00034
   Tustanowski J, 2009, J Wound Care, V18, P449
   Tyagi V, 2019, ORTHOPEDICS, V42, pE539, DOI 10.3928/01477447-20190906-06
   White IR, 2015, STATA J, V15, P951, DOI 10.1177/1536867X1501500403
NR 50
TC 21
Z9 22
U1 1
U2 6
PU CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS
PI PHILADELPHIA
PA CURTIS CENTER, INDEPENDENCE SQUARE WEST, PHILADELPHIA, PA 19106-3399 USA
SN 0883-5403
EI 1532-8406
J9 J ARTHROPLASTY
JI J. Arthroplast.
PD JUL
PY 2021
VL 36
IS 7
BP 2612
EP 2629
DI 10.1016/j.arth.2021.02.047
EA JUN 2021
PG 18
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA SR5II
UT WOS:000661074600065
PM 33707123
OA Bronze
DA 2026-07-24
ER

PT J
AU Galstyan, GR
   Tokmakova, AY
   Zaitseva, EL
   Doronina, LP
   Voronkova, IA
   Molchkov, RV
AF Galstyan, G. R.
   Tokmakova, A. Yu.
   Zaitseva, E. L.
   Doronina, L. P.
   Voronkova, I. A.
   Molchkov, R. V.
TI Comparative evaluation of the intensity of reparative processes in the
   lower extremity soft tissues of diabetic patients receiving local
   negative pressure wound treatment and standard wound care
SO TERAPEVTICHESKII ARKHIV
LA Russian
DT Article
DE diabetes mellitus; chronic wounds; local treatment; negative pressure
   wound therapy; vacuum; repair; immunohistochemistry; histology
ID FOOT ULCERS; THERAPY
AB Aim. To study the intensity of soft tissue repair in patients with diabetic foot syndrome (DFS) during local negative pressure wound treatment versus standard wound care.
   Subjects and methods. The investigators estimated the clinical (wound sizes, local tissue oxygenation), histological (light microscopy), and immunohistochemical (CD31, CD68, MMP-9, and TIMP-1) markers for reparative processes in patients with DFS during vacuum therapy versus standard wound care. Forty-two patients with the neuropathic and neuroischemic (without critical ischemia) forms of DFS were examined after debridement. In the perioperative period, 21 patients received negative pressure wound therapy and 21 had standard wound care.
   Results. During vacuum therapy, the area and depth of wound defects decreased by 19.8 +/- 7.8 and 42.8 +/- 5.6%, respectively (p=0.002) (as compared to the baseline data). In the control group, these indicators were 17.0 +/- 19.4 and 16.6 +/- 21.6% (p=0.002). There was a significant intensification of local microhemodynamics according to transcutaneous oximetry readings in the negative pressure wound treatment group. After 9 2 days of treatment, histological examination of granulation tissue revealed a significant reduction in edema, cessation of inflammatory infiltration, and formation of mature granulation tissue in Group 1. Immunohistological examination indicated a more obvious increase in the count of macrophages (CD68 staining) and a significant increment in the number of newly formed vessels, as evidenced by anti-CD31 antibody staining. During the treatment, there was a decline of the expression of MMP-9 and an increase in that of TIMP-1, as compared to those in the control group.
   Conclusion. The findings are indicative of the enhanced intensity of reparative processes in patients with DFS during vacuum therapy versus standard wound care, resulting in more rapidly decreased wound sizes, increased local microhemodynamics, reduced inflammation, and accelerated wound transition from the inflammatory to the proliferative phase.
C1 [Galstyan, G. R.; Tokmakova, A. Yu.; Zaitseva, E. L.; Doronina, L. P.; Voronkova, I. A.; Molchkov, R. V.] Minist Hlth Russia, Endocrinol Res Ctr, Moscow, Russia.
C3 Ministry of Health of the Russian Federation; Russian Academy of Medical
   Sciences; Endocrinology Research Centre
RP Zaitseva, EL (通讯作者)，Minist Hlth Russia, Endocrinol Res Ctr, Moscow, Russia.
EM zai.kate@gmail.com
RI Tokmakova, Alla/HHR-9409-2022
OI Tokmakova, Alla/0000-0003-2474-9924
CR [Anonymous], 2015, IWGDF GUID DIAB FOOT
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bassetto F, 2012, J PLAST RECONSTR AES, V65, P91, DOI 10.1016/j.bjps.2011.08.016
   Blakytny R, 2006, DIABETIC MED, V23, P594, DOI 10.1111/j.1464-5491.2006.01773.x
   Blakytny Robert, 2000, Journal of Pathology, V190, P589, DOI 10.1002/(SICI)1096-9896(200004)190:5<589::AID-PATH553>3.0.CO;2-T
   Hasan MY, 2015, DIABET FOOT ANKLE, V6, DOI 10.3402/dfa.v6.27618
   Lavery Lawrence A, 2014, J Diabetes Sci Technol, V8, P346
   Liu Y, 2009, DIABETES CARE, V32, P117, DOI 10.2337/dc09-1394
   Muller M, 2008, DIABETIC MED, V25, P419, DOI 10.1111/j.1464-5491.2008.02414.x
   OBOLENSKIY VN, 2011, ISPOLZOVAMIYE PRINTE
   REDAKTSIYEY II, 2015, ALGORITMY SPETSIALIZ
   Stansby G, 2010, J WOUND CARE, V19, P496, DOI 10.12968/jowc.2010.19.11.79706
   2015, ATLAS DIABETA IDF
NR 13
TC 4
Z9 4
U1 0
U2 4
PU IZDATELSTVO MEDITSINA
PI MOSCOW
PA PETROVERIGSKII PER 6-8, K-142 MOSCOW, RUSSIA
SN 0040-3660
EI 2309-5342
J9 TERAPEVT ARKH
JI Ter. Arkhiv
PY 2016
VL 88
IS 10
BP 19
EP 24
DI 10.17116/terarkh2016881019-24
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA ED8ZK
UT WOS:000389159400003
PM 27801415
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Moloney, GB
   Boakye, LAT
   Cluts, LM
   Palmeri, C
AF Moloney, Gele Brown
   Boakye, Lorraine Akua Takyiwaa
   Cluts, Landon Myers
   Palmeri, Christine
TI Administration of Prophylactic Enoxaparin on the Morning of Surgery Does
   Not Increase Risk of Blood Transfusion or Wound Drainage Following
   Internal Fixation of Geriatric Femur Fractures
SO JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
LA English
DT Article
ID VENOUS THROMBOEMBOLISM PROPHYLAXIS; HIP FRACTURE; TRAUMA;
   THROMBOPROPHYLAXIS; OUTCOMES
AB Background:Despite standard use of chemoprophylaxis, 30-day incidence of venous thromboembolism after geriatric, those older than 60 years, femur fracture surgery is reported to be up to 10%. Missing one dose of enoxaparin has been proven to increase the risk of developing venous thromboembolism. It is commonplace to hold preoperative chemoprophylaxis the morning of surgery because of concern for intraoperative bleeding or wound drainage. We sought to determine whether administration of prophylactic enoxaparin the morning of surgery resulted in an increased rate of blood transfusion or wound drainage in geriatric patients undergoing femur fracture treatment.Methods:We retrospectively reviewed patients older than 60 years who underwent internal fixation of an isolated femur fracture, including femoral neck, intertrochanteric, subtrochanteric, femoral shaft, and distal femur fractures, at a Level 1 trauma center. Medical records, hospital billing data, and radiographs were reviewed to determine patient characteristics such as Charlson Comorbidity Index, enoxaparin dosing, packed red blood cell transfusion, and persistent wound drainage, defined as any drainage requiring utilization of closed incision negative pressure wound therapy. Thirty-day mortality served as the secondary outcome measure.Results:Five hundred seven patients were included. One hundred sixty-four (32%) received enoxaparin on the morning of surgery, whereas 343 (68%) did not. 27% of patients received PRBC transfusion, and this did not differ between groups (27% vs. 28%, P = 0.72). Subgroup analysis of fixation strategies revealed no difference in the frequency of blood transfusion for any fixation type as related to the timing of enoxaparin dosage. Utilization of closed incision negative pressure wound therapy for the treatment of postoperative wound drainage did not differ between dosing groups. No difference was observed in thirty-day mortality between groups (2.4% vs. 2.7%, P = 0.9).Discussion:Administration of a prophylactic dose of enoxaparin on the morning of surgery does not seem to increase the rate of postoperative blood transfusion or wound drainage after fixation of geriatric femur fracture.
C1 [Moloney, Gele Brown; Boakye, Lorraine Akua Takyiwaa; Cluts, Landon Myers; Palmeri, Christine] Univ Pittsburgh, Med Ctr, Dept Orthopaed Surg, Pittsburgh, PA 15260 USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); University
   of Pittsburgh
RP Moloney, GB (通讯作者)，Univ Pittsburgh, Med Ctr, Dept Orthopaed Surg, Pittsburgh, PA 15260 USA.
EM moloneygb@upmc.edu; lac213@pitt.edu; cipalmeri04@gmail.com
RI Boakye, Lorraine/GZK-6904-2022
OI Boakye, Lorraine/0000-0002-0525-5825
CR Bandle J, 2014, J TRAUMA ACUTE CARE, V76, P213, DOI 10.1097/TA.0b013e3182aa2fa9
   Browne JA, 2009, J TRAUMA, V66, P809, DOI 10.1097/TA.0b013e31816166bb
   COOPER C, 1992, OSTEOPOROSIS INT, V2, P285, DOI 10.1007/BF01623184
   Falck-Ytter Y, 2012, CHEST, V141, pE278S, DOI 10.1378/chest.11-2404
   GEERTS WH, 1994, NEW ENGL J MED, V331, P1601, DOI 10.1056/NEJM199412153312401
   Ghasemi A, 2012, INT J ENDOCRINOL MET, V10, P486, DOI 10.5812/ijem.3505
   Hecht JP, 2021, J TRAUMA ACUTE CARE, V90, P54, DOI 10.1097/TA.0000000000002912
   Hou GJ, 2014, INJURY, V45, P1932, DOI 10.1016/j.injury.2014.08.033
   Imran JB, 2018, J TRAUMA ACUTE CARE, V85, P867, DOI 10.1097/TA.0000000000002024
   Jang SY, 2020, J KOREAN MED SCI, V35, DOI 10.3346/jkms.2020.35.e313
   Jones CW, 2018, J ARTHROPLASTY, V33, P224, DOI 10.1016/j.arth.2017.07.046
   Jones DL, 2019, J ORTHOP TRAUMA, V33, P570, DOI 10.1097/BOT.0000000000001563
   Kagan R, 2021, J SURG EDUC, V78, P1269, DOI 10.1016/j.jsurg.2020.11.011
   Leer-Salvesen S, 2017, ACTA ORTHOP, V88, P48, DOI 10.1080/17453674.2016.1235427
   Lin YC, 2018, THROMB RES, V172, P120, DOI 10.1016/j.thromres.2018.10.014
   Liu ZD, 2016, BMC MUSCULOSKEL DIS, V17, DOI 10.1186/s12891-016-0917-y
   Louis SG, 2014, JAMA SURG, V149, P365, DOI 10.1001/jamasurg.2013.3963
   Lowe JA, 2020, J ORTHOP TRAUMA, V34, P418, DOI 10.1097/BOT.0000000000001790
   Luangwaranyoo A, 2020, GERIATR ORTHOP SURG, V11, DOI 10.1177/2151459320972993
   MacDonald DRW, 2020, J ORTHOP TRAUMA, V34, pS70, DOI 10.1097/BOT.0000000000001939
   McDonald M, 2021, J ORTHOP TRAUMA, V35, P245, DOI 10.1097/BOT.0000000000001966
   Nam D, 2018, J AM ACAD ORTHOP SUR, V26, P295, DOI 10.5435/JAAOS-D-17-00054
   Panteli M, 2021, J CLIN MED, V10, DOI 10.3390/jcm10030540
   Sagi HC, 2015, J ORTHOP TRAUMA, V29, pe355, DOI 10.1097/BOT.0000000000000387
   Shorr AF, 2001, CRIT CARE MED, V29, P1659, DOI 10.1097/00003246-200109000-00001
   Trivedi NN, 2019, J ORTHOP TRAUMA, V33, P216, DOI 10.1097/BOT.0000000000001435
   Xia ZN, 2018, J ORTHOP SURG RES, V13, DOI 10.1186/s13018-018-0998-4
   Yoon JY, 2020, GERIATR GERONTOL INT, V20, P1151, DOI 10.1111/ggi.14055
NR 28
TC 4
Z9 4
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1067-151X
EI 1940-5480
J9 J AM ACAD ORTHOP SUR
JI J. Am. Acad. Orthop. Surg.
PD MAR 15
PY 2023
VL 31
IS 6
BP 305
EP 311
DI 10.5435/JAAOS-D-22-00233
PG 7
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 9S4WZ
UT WOS:000946343300008
PM 36520993
DA 2026-07-24
ER

PT J
AU Yang, YP
   Yu, LY
   Wang, M
   Mu, Y
   Li, JN
   Shang, FJ
   Wu, XF
   Liu, TJ
   Shi, J
AF Yang, Yong-Ping
   Yu, Ling-Yun
   Wang, Min
   Mu, Yu
   Li, Jian-Nan
   Shang, Feng-Jia
   Wu, Xian-Feng
   Liu, Tong-Jun
   Shi, Jian
TI A new surgical approach of direct perineal wound full-thick closure for
   perineal wound of abdominoperineal resection for rectal carcinoma: A
   prospective cohort trial
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE APR; direct perineal wound full-thick closure; hypoalbuminemia
ID NEGATIVE-PRESSURE THERAPY; SHORT-TERM OUTCOMES; RISK-FACTORS; EXCISION;
   CANCER; RECONSTRUCTION; COMPLICATIONS; EXPERIENCE; RADIOTHERAPY
AB Perineal wound complications after APR have high morbidity in the colorectal surgical department. Although some approaches have been figured out to solve this clinical focus, the outcomes are still not satisfied. Herein, this prospective comparative clinical trial has been designed to evaluate a new surgical procedure of direct perineal wound full-thick closure (DPWC), compared with conventional perineal wound closure (CPWC), with hopes of making wound healing with less complications. In addition, an evaluation of an incision negative wound pressure therapy, as another focus in this field, was also analysed in the DPWC group. A total of 44 participants in our department were recruited from March 2018 to March 2020, divided into two groups randomly, CPWC group and DPWC group. The patients' characteristics, such as age, gender, BMI, smoking, alcohol consumption, comorbidities, CEA level, and high-risk of invasion, were recorded without statistical significance between the CPWC group and DPWC group. After the same standard abdominal phase, these two groups were performed in different perineal phases. And then, operative and postoperative outcomes were analysed with different statistical methods. Data on wound healing time and length of stay in the DPWC group were shorter than those in the CPWC group (P < .05). Furthermore, cases of wound infection within 30 days in the DPWC group were also less than that in the CPWC group (P < .05). However, no difference was found between the incisional negative pressure wound therapy assisted group (NPA group) and non- incisional negative pressure wound therapy assisted group (non-NPA group). During this study, hypoalbuminemia, as an independent high-risk factor, impacted perineal wound healing. (P= .0271) In conclusion, DPWC is a new surgical approach, which can lead to a better outcome than DPWC, and it can be another surgical procedure for clinicians. In addition, hypoalbuminemia should be interfered for avoiding perineal wound complications.
C1 [Yang, Yong-Ping; Wang, Min; Mu, Yu; Li, Jian-Nan; Shang, Feng-Jia; Wu, Xian-Feng; Liu, Tong-Jun; Shi, Jian] Second Hosp Jilin Univ, Dept Gen Surg, Changchun 130041, Peoples R China.
   [Yu, Ling-Yun] First Hosp Jilin Univ, Dept Ear Nose & Throat Surg, Changchun, Peoples R China.
C3 Jilin University; Jilin University
RP Liu, TJ; Shi, J (通讯作者)，Second Hosp Jilin Univ, Dept Gen Surg, Changchun 130041, Peoples R China.
EM tongjunliu@163.com; dr.shi@live.cn
RI Li, Jiannan/ABH-3120-2021
OI Li, Jiannan/0000-0001-9744-7666; Yang, Yongping/0000-0001-6605-1343
CR Althumairi AA, 2016, WORLD J SURG, V40, P1755, DOI 10.1007/s00268-016-3450-0
   Artioukh DY, 2007, COLORECTAL DIS, V9, P362, DOI 10.1111/j.1463-1318.2006.01159.x
   Barker T, 2013, COLORECTAL DIS, V15, P1177, DOI 10.1111/codi.12286
   Bhalla A, 2015, GUT, V64, pA337, DOI 10.1136/gutjnl-2015-309861.733
   Bullard KM, 2005, DIS COLON RECTUM, V48, P438, DOI 10.1007/s10350-004-0827-1
   CHANG CC, 2019, WORLD J SURG ONCOL, V17
   Christensen HK, 2011, DIS COLON RECTUM, V54, P711, DOI 10.1007/DCR.0b013e3182163c89
   Christian CK, 2005, DIS COLON RECTUM, V48, P43, DOI 10.1007/s10350-004-0855-x
   Dalton RSJ, 2012, SURG-J R COLL SURG E, V10, P342, DOI 10.1016/j.surge.2011.10.001
   De Broux E, 2005, DIS COLON RECTUM, V48, P476, DOI 10.1007/s10350-004-0784-8
   De Nardi P, 2015, ANN SURG ONCOL, V22, P2997, DOI 10.1245/s10434-015-4368-8
   den Dulk M, 2009, EUR J CANCER, V45, P1175, DOI 10.1016/j.ejca.2008.11.039
   Devalia HL, 2008, INT WOUND J, V5, P40, DOI 10.1111/j.1742-481X.2007.00351.x
   Dijkstra EA, 2020, TECH COLOPROCTOL, V24, P855, DOI 10.1007/s10151-020-02248-z
   GORBACH SL, 1991, REV INFECT DIS, V13, pS815
   Han JG, 2019, DIS COLON RECTUM, V62, P1477, DOI 10.1097/DCR.0000000000001495
   Han JG, 2012, AM J SURG, V204, P274, DOI 10.1016/j.amjsurg.2012.05.001
   Han JG, 2010, DIS COLON RECTUM, V53, P219, DOI 10.1007/DCR.0b013e3181b715b5
   Haubner F, 2012, RADIAT ONCOL, V7, DOI 10.1186/1748-717X-7-162
   Horch RE, 2015, J WOUND CARE, V24, P21, DOI 10.12968/jowc.2015.24.Sup4b.21
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Kobayashi N, 2004, WOUND REPAIR REGEN, V12, P109, DOI 10.1111/j.1524-475X.2004.tb00002.x
   Kokosis G, 2017, AM J SURG, V213, P371, DOI 10.1016/j.amjsurg.2016.04.018
   Lefevre JH, 2009, ANN SURG, V250, P707, DOI 10.1097/SLA.0b013e3181bce334
   Marshall MJ, 2012, COLORECTAL DIS, V14, P12, DOI 10.1111/codi.12044
   Matsuda K, 2009, LANGENBECK ARCH SURG, V394, P65, DOI 10.1007/s00423-008-0381-8
   Miles W E, 1971, CA Cancer J Clin, V21, P361, DOI 10.3322/canjclin.21.6.361
   Musters GD, 2014, INT J COLORECTAL DIS, V29, P1151, DOI 10.1007/s00384-014-1967-y
   Musters GD, 2014, DIS COLON RECTUM, V57, P1129, DOI 10.1097/DCR.0000000000000182
   Russell L, 2001, Br J Nurs, V10, pS44
   Semsarzadeh NN, 2015, PLAST RECONSTR SURG, V136, P592, DOI 10.1097/PRS.0000000000001519
   Sinna R, 2013, J VISC SURG, V150, P9, DOI 10.1016/j.jviscsurg.2013.02.001
   Vaughan-Shaw PG, 2011, ANN ROY COLL SURG, V93, P451, DOI 10.1308/003588411X588621
   Wiatrek Rebecca L, 2008, Clin Colon Rectal Surg, V21, P76, DOI 10.1055/s-2008-1055325
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Zhang YG, 2017, MEDICINE, V96, DOI [10.1097/MD.0000000000004822, 10.1097/md.0000000000004822]
NR 36
TC 4
Z9 4
U1 0
U2 13
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD DEC
PY 2020
VL 17
IS 6
BP 1817
EP 1828
DI 10.1111/iwj.13470
EA AUG 2020
PG 12
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA PE3BU
UT WOS:000555411400001
PM 32755065
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Dias, TA
   Fernandes, DR
   dos Santos, BN
   dos Reis, PED
   Margatho, AS
   Silveira, RCDP
AF Dias, Thais Almeida
   Fernandes, Daiane Rubinato
   dos Santos, Bruna Nogueira
   dos Reis, Paula Elaine Diniz
   Margatho, Amanda Salles
   Silveira, Renata Cristina de Campos Pereira
TI Dressing to prevent surgical site infection in adult patients with
   cancer: a systematic review with meta-analysis
SO SUPPORTIVE CARE IN CANCER
LA English
DT Review
DE Oncology surgery; Surgical wound infection; Surgical wound; Bandages;
   Occlusive dressings; Systematic review
ID PRESSURE WOUND THERAPY; SURGERY; TRIAL; LAPAROTOMY; OINTMENT
AB Purpose To identify the most effective dressing for application to surgical wounds with primary closure to prevent surgical site infection (SSI) in adult patients with cancer undergoing elective surgeries. Methods This systematic review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis, with online searches conducted in the CINHAL, Cochrane Central, LILACS, PubMed, Scopus, Embase, Livivo, and Web of Science databases. An additional search was conducted in gray literature using Google Scholar. The risk of bias was assessed using RoB 2.0. The certainty of evidence was evaluated using the Grading of Recommendations Assessment and Development and Evaluation, and the results were synthesized in a descriptive manner and using meta-analysis. Results Eleven randomized clinical trials were conducted to compare different types of dressing-silver dressing with absorbent dressing (n = 3), mupirocin dressing with paraffin/no dressing (n = 1), honey-based dressing with absorbent dressing (n = 1), vitamin E and silicone-containing dressing with absorbent dressing (n = 1), and negative pressure wound therapy with absorbent dressing (n = 4)-and compare the usage duration of absorbent dressing (n = 1). Nine trials presented a low risk of bias, and two were classified as having uncertain bias. Compared with absorbent dressing, silver dressing did not reduce the risk of developing any type of SSI in 894 clinical trial participants (risk relative RR: 0.72; 95% confidence interval [CI] [0.44, 1.17] p = 0.18). Compared with absorbent dressing, negative pressure wound therapy did not reduce the risk of developing any type of SSI in the 1041 participants of two clinical trials (RR 0.68; 95% CI [0.31, 1.26] p = 0.22). The certainty of evidence of the three meta-analyses was considered low or very low for the prevention of SSI. We believe that this low certainty of evidence can be improved by conducting new studies in the future. Conclusion There is no evidence regarding which dressing is the most effective in preventing SSI in adult patients with cancer.
C1 [Dias, Thais Almeida; Fernandes, Daiane Rubinato; dos Santos, Bruna Nogueira; Margatho, Amanda Salles; Silveira, Renata Cristina de Campos Pereira] Univ Sao Paulo EERP USP, Ribeirao Preto Sch Nursing, Prof Helio Lourenco St 3900, Sao Paulo, Vila Monte Aleg, Brazil.
   [dos Reis, Paula Elaine Diniz] Univ Brasilia, BR-70910900 Brasilia, DF, Brazil.
C3 Universidade de Brasilia
RP Silveira, RCDP (通讯作者)，Univ Sao Paulo EERP USP, Ribeirao Preto Sch Nursing, Prof Helio Lourenco St 3900, Sao Paulo, Vila Monte Aleg, Brazil.
EM recris@eerp.usp.br
RI Martins, Bruna/ODJ-9030-2025; Pereira Silveira, Renata Cristina de
   Campos/K-7350-2012; Diniz dos Reis, Paula Elaine/AAS-1366-2020
OI Pereira Silveira, Renata Cristina de Campos/0000-0002-2883-3640;
   Margatho, Amanda/0000-0002-1006-9357; Dias, Thais
   Almeida/0000-0002-7601-3399; Diniz dos Reis, Paula
   Elaine/0000-0002-9782-3366
CR Anatone AJ, 2020, J AM ACAD ORTHOP SUR, V28, pE923, DOI 10.5435/JAAOS-D-19-00582
   [Anonymous], 2022, ROB 2 ROBINS
   Balshem H, 2011, J CLIN EPIDEMIOL, V64, P401, DOI 10.1016/j.jclinepi.2010.07.015
   Barbosa CNB, 2012, ONCOLOGIA BASICA
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Biffi R, 2012, WORLD J SURG ONCOL, V10, DOI 10.1186/1477-7819-10-94
   Brierley R, 2015, LANCET ONCOL, V16, P1187, DOI 10.1016/S1470-2045(15)00306-X
   Camargo IM, 2012, POTENCIAL CICATRIZAN
   Dixon AJ, 2006, BRIT J SURG, V93, P937, DOI 10.1002/bjs.5400
   Dumville JC, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003091.pub4
   Ferlay J, 2021, INT J CANCER, V149, P778, DOI 10.1002/ijc.33588
   Guinan John L, 2003, Oncology (Williston Park), V17, P415
   Higgins JPT., 2019, Cochrane Handbook for Systematic Reviews of Interventions, P1, DOI [DOI 10.1002/9781119536604.CH8, DOI 10.1002/9781119536604]
   Instituto Nacional de Cancer, 2019, Estimativa 2020: Incidencia de Cancer no Brasil Internet
   Javed AA, 2019, ANN SURG, V269, P1034, DOI 10.1097/SLA.0000000000003056
   Kahl Elizabete Rosane Palharini Yoneda, 2019, Rev. Gaúcha Enferm., V40, pe20180200, DOI [10.1590/1983-1447.2019.20180200, 10.1590/1983-1447.2019.20180200]
   Ker H, 2019, J SURG RES, V235, P308, DOI 10.1016/j.jss.2018.10.016
   Leitao MM Jr, 2021, OBSTET GYNECOL, V137, P334, DOI 10.1097/AOG.0000000000004243
   National Healthcare Safety Network, 2022, Surgical site infection event (SSI)
   National Institute for Health and Care Excellence, 2019, PICO negative pressure wound dressings for closed surgical incisions
   O'Donnell RL, 2019, BMJ OPEN, V9, DOI 10.1136/bmjopen-2018-024853
   Page MJ, 2021, BMJ-BRIT MED J, V372, DOI 10.1136/bmj.n71
   Poruk KE, 2016, HPB, V18, P893, DOI 10.1016/j.hpb.2016.07.011
   Rayyan Systems Inc, 2022, WELC
   Robson V, 2012, BRIT J ORAL MAX SURG, V50, P321, DOI 10.1016/j.bjoms.2011.07.014
   Rolston KVI, 2017, INFECT DIS THER, V6, P69, DOI 10.1007/s40121-017-0146-1
   Ruiz-Tovar J, 2019, J HOSP INFECT, V102, P262, DOI 10.1016/j.jhin.2018.10.021
   Ruiz-Tovar J, 2015, J AM COLL SURGEONS, V221, P424, DOI 10.1016/j.jamcollsurg.2015.04.019
   Schunemann H BJ., 2013, GRADE handbook
   Shen P, 2017, J AM COLL SURGEONS, V224, P726, DOI 10.1016/j.jamcollsurg.2016.12.028
   Struik GM, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0195715
   Sullivan R, 2015, LANCET ONCOL, V16, P1193, DOI [10.1016/s1470-2045(15)00223-5, 10.1016/S1470-2045(15)00223-5]
   Sung H, 2021, CA-CANCER J CLIN, V71, P209, DOI 10.3322/caac.21660
   Tang Y, 2020, MED SCI MONITOR, V26, DOI 10.12659/MSM.928054
   Veiga DF, 2016, PLOS ONE, V11, DOI 10.1371/journal.pone.0166356
   Webster J, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub4
   Xu ZH, 2020, INT J COLORECTAL DIS, V35, P2147, DOI 10.1007/s00384-020-03706-8
   Zheng YQ, 2021, INFECT DIS THER, V10, P871, DOI 10.1007/s40121-021-00433-7
NR 38
TC 5
Z9 5
U1 0
U2 6
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0941-4355
EI 1433-7339
J9 SUPPORT CARE CANCER
JI Support. Care Cancer
PD JAN
PY 2023
VL 31
IS 1
AR 11
DI 10.1007/s00520-022-07467-8
PG 13
WC Oncology; Health Care Sciences & Services; Rehabilitation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology; Health Care Sciences & Services; Rehabilitation
GA 7B1HO
UT WOS:000898893700010
PM 36512091
DA 2026-07-24
ER

PT J
AU Strugala, V
   Martin, R
AF Strugala, Vicki
   Martin, Robin
TI Meta-Analysis of Comparative Trials Evaluating a Prophylactic Single-Use
   Negative Pressure Wound Therapy System for the Prevention of Surgical
   Site Complications
SO SURGICAL INFECTIONS
LA English
DT Article
DE postoperative complication; prophylaxis; surgical site infection; wound
   infection; wound management
ID RANDOMIZED CONTROLLED-TRIAL; PRIMARY HIP; SURGERY; INFECTION; INCISION;
   CLOSURE; CARE; DEHISCENCE; REDUCTION; DRESSINGS
AB Background: We report the first meta-analysis on the impact of prophylactic use of a specific design of negative pressure wound therapy (NPWT) device on surgical site complications.
   Methods: Articles were identified in which the specific single-use NPWT device (PICO, Smith & Nephew) was compared with standard care for surgical site infection (SSI), dehiscence, or length of stay (LOS). Risk ratio (RR) 95% confidence interval (CI) (SSI; dehiscence) or mean difference in LOS 95% CI was calculated using RevMan v5.3.
   Results: There were 1863 patients (2202 incisions) represented by 16 articles. Among 10 randomized studies, there was a significant reduction in SSI rate of 51% from 9.7% to 4.8% with NPWT intervention (RR 0.49 [95% CI 0.34-0.69] p<0.0001). There were six observational studies assessing reduction in SSI rate of 67% from 22.5% to 7.4% with NPWT (RR 0. 32 [95% CI 0.18-0.55] p<0.0001). Combining all 16 studies, there was a significant reduction in SSI of 58% from 12.5% to 5.2% with NPWT (RR 0.43 [95% CI 0.32-0.57] p<0.0001). Similar effects were seen irrespective of the kind of surgery (orthopedic, abdominal, colorectal, or cesarean section), although the numbers needed to treat (NNT) were lower in operations with higher frequencies of complications. There was a significant reduction in dehiscence from 17.4% to 12.8% with NPWT (RR 0.71 [95% CI 0.54-0.92] p<0.01). The mean reduction in hospital LOS by NPWT was also significant (-0.47 days [95% CI -0.71 to -0.23] p<0.0001).
   Conclusions: The significant reduction in SSI, wound dehiscence, and LOS on the basis of pooled data from 16 studies shows a benefit of the PICO single-use NPWT system compared with standard care in closed surgical incisions.
C1 [Strugala, Vicki; Martin, Robin] Smith & Nephew Plc, Adv Wound Management Clin Sci & Med Affairs, 101 Hessle Rd, Kingston Upon Hull HU3 2BN, N Humberside, England.
RP Martin, R (通讯作者)，Smith & Nephew Plc, Adv Wound Management Clin Sci & Med Affairs, 101 Hessle Rd, Kingston Upon Hull HU3 2BN, N Humberside, England.
EM robin.martin@smith-nephew.com
RI strugala, vicki/JEZ-4021-2023
OI Martin, Robin/0000-0002-9314-0437
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe276, DOI [10.1016/s1473-3099(16)30402-9, 10.1016/s1473-3099(16)30398-x, 10.1016/S1473-3099(16)30398-X]
   Anderson V, 2014, EVID BASED MIDWIFERY, V12, P23
   [Anonymous], WOUND ESSENTIALS
   [Anonymous], 2009, BMJ-BRIT MED J, V21, P7, DOI [DOI 10.1136/bmj.b2535, 10.1371/journal.pmed.1000097, DOI 10.7326/0003-4819-151-4-200908180-00135]
   [Anonymous], P EWMA MAY 11 13 BRE
   [Anonymous], COCHRANE DATABASE SY
   [Anonymous], 2016, INCISIONAL NEGATIVE
   [Anonymous], WOUND REPAIR REGEN
   [Anonymous], 2016, CLOSED SURG INCISION
   [Anonymous], BAAPS ANN SCI M SEPT
   [Anonymous], P WUWHS C SEPT 25 29
   [Anonymous], CLIN SERV J APR
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Artinyan A, 2015, ANN SURG, V261, P497, DOI 10.1097/SLA.0000000000000854
   Arundel C, 2016, TRIALS, V17, DOI 10.1186/s13063-016-1661-1
   Beecher SM, 2016, BRIT J SURG, V103, P391, DOI 10.1002/bjs.10068
   Bonds AM, 2013, DIS COLON RECTUM, V56, P1403, DOI 10.1097/DCR.0b013e3182a39959
   Chaboyer W, 2014, HEALTHCARE, V2, P417, DOI 10.3390/healthcare2040417
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   Gillespie BM, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2015-010287
   Gillespie BM, 2015, SURG INNOV, V22, P488, DOI 10.1177/1553350615573583
   Hasselmann J, 2015, Surgical Science, V06, P562, DOI [10.4236/ss.2015.612080, DOI 10.4236/SS.2015.612080]
   Heard C, 2017, J TISSUE VIABILITY, V26, P79, DOI 10.1016/j.jtv.2016.06.001
   Hester T, 2015, Advances in Orthopedic Surgery, V2015, P1, DOI [10.1155/2015/247324, 10.1155/2015/247324, DOI 10.1155/2015/247324]
   Hickson E, 2015, SURG INFECT, V16, P174, DOI 10.1089/sur.2014.145
   Higgins J, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.ED000049
   Holt R, 2015, BRIT J HOSP MED, V76, P217, DOI 10.12968/hmed.2015.76.4.217
   Hudson DA, 2015, INT WOUND J, V12, P195, DOI 10.1111/iwj.12080
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Ingargiola Michael J, 2013, Eplasty, V13, pe49
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Leaper DJ, 2015, INT WOUND J, V12, P357, DOI 10.1111/iwj.12243
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   MANTEL N, 1959, JNCI-J NATL CANCER I, V22, P719
   Matsumoto T, 2015, FOOT ANKLE INT, V36, P787, DOI 10.1177/1071100715574934
   Nordmeyer M, 2016, INT WOUND J, V13, P1176, DOI 10.1111/iwj.12436
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Pellino G, 2014, INT J SURG, V12, pS64, DOI 10.1016/j.ijsu.2014.08.378
   Pellino G, 2014, SURG INNOV, V21, P204, DOI 10.1177/1553350613496906
   Povsic MK, 2016, SURG INFECT, V17, P700, DOI 10.1089/sur.2015.187
   Sandy-Hodgetts K, 2017, J WOUND CARE, V26, pS23, DOI 10.12968/jowc.2017.26.Sup2.S23
   Sandy-Hodgetts Kylie, 2015, JBI Database System Rev Implement Rep, V13, P253, DOI [10.11124/jbisrir-2015-1687, 10.11124/jbisrir-2015-1687]
   Selvaggi Francesco, 2014, Surg Technol Int, V24, P83
   Semsarzadeh NN, 2015, PLAST RECONSTR SURG, V136, P592, DOI 10.1097/PRS.0000000000001519
   Tanner J, 2015, SURGERY, V158, P66, DOI 10.1016/j.surg.2015.03.009
   Tuffaha HW, 2015, J SURG RES, V195, P612, DOI 10.1016/j.jss.2015.02.008
   Tuuli MG, 2017, AM J OBSTET GYNECOL, V216, pS245, DOI 10.1016/j.ajog.2016.11.670
   Uchino M, 2016, DIGEST SURG, V33, P449, DOI 10.1159/000446550
   Webb LX, 2008, J ORTHOP TRAUMA, V22, pS135, DOI 10.1097/BOT.0b013e31818956ce
   Witt-Majchrzak Anna, 2015, Pol Przegl Chir, V86, P456, DOI [10.2478/pjs-2014-0082, 10.2478/pjs-2014-0082]
   Young SR, 2013, INT WOUND J, V10, P383, DOI 10.1111/j.1742-481X.2012.00994.x
NR 53
TC 102
Z9 131
U1 0
U2 13
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD OCT
PY 2017
VL 18
IS 7
BP 810
EP 819
DI 10.1089/sur.2017.156
PG 10
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA FI3CP
UT WOS:000411834300009
PM 28885895
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Xiao, SA
   Liu, N
   Cui, YW
   Li, H
   Dong, YC
   Tang, JZ
   Zhang, H
   Wang, WX
   Bian, YQ
   Li, J
   Li, XY
AF Xiao, Shu-Ao
   Liu, Ni
   Cui, Yi-Wei
   Li, Hang
   Dong, Yu-Chen
   Tang, Jie-Zhang
   Zhang, Hao
   Wang, Wen-Xuan
   Bian, Yong-Qian
   Li, Jing
   Li, Xue-Yong
TI Negative pressure-induced fibroblast activation for wound healing
   through the Piezo1-Ca2+-NFAT3 signaling pathway
SO BURNS & TRAUMA
LA English
DT Article
DE Negative pressure wound therapy; Finite element analysis; Fibroblasts;
   Piezo1; calcineurin/NFAT signaling pathway; Wound healing
ID PROLIFERATION; THERAPY; STIMULATION; MIGRATION; MECHANISM
AB Background Negative pressure wound therapy (NPWT) is widely used to promote wound healing, yet the mechanotransduction mechanisms underlying its efficacy remain unclear because of the absence of precise and controllable in vitro negative pressure loading devices for cellular-level studies. Therefore, this study aims to develop a precise and controllable in vitro negative pressure loading device and to elucidate the mechanotransduction mechanism by which negative pressure activates dermal fibroblasts during wound healing.Methods We developed a high-precision negative pressure loading device compatible with six-well plates, facilitating independent and intelligent control over negative pressure values, durations, and modes for each well. To validate the uniformity and stability of the negative pressure environment, finite element analysis (FEA) was implemented. The mechanism was explored using proteomic profiling of negative pressure-treated fibroblasts, complemented by molecular interrogation of Piezo1 expression and calcium signaling dynamics. The results of functional studies integrated genetic silencing and pharmacological modulation of the pathway, with in vivo confirmation through SD rat-based NPWT experiments.Results FEA confirmed a stable pressure distribution within the negative pressure chamber. The cells experienced predominantly compressive stresses that scaled linearly with the applied pressure, reaching -2 kPa at -40 mmHg. We found that applying a continuous negative pressure of -40 mmHg for 2 hours significantly activated dermal fibroblasts. TMT-based proteomic analysis revealed the upregulation of Piezo1 in negative pressure-treated dermal fibroblasts, which was further confirmed by molecular and immunohistochemical analyses of both cellular and granulation tissue samples. Pharmacological inhibition or knockdown of Piezo1 attenuated negative pressure-induced dermal fibroblast activation in vivo and in vitro. Mechanistically, we determined that Piezo1-mediated Ca2+ influx and the calcineurin/NFAT3 signaling pathway are critically enhanced during this process.Conclusions This study revealed that the Piezo1-Ca2+-NFAT3 mechanotransduction axis is the central pathway that mediates the therapeutic effects of NPWT. This work lays the foundational groundwork for elucidating the biomechanical mechanisms of negative pressure and reveals new approaches for research in tissue engineering and regenerative medicine.
C1 [Xiao, Shu-Ao] Fourth Mil Med Univ, Xijing Hosp, Dept Plast Surg, 127 Changle West Rd, Xian 710032, Shaanxi, Peoples R China.
   [Liu, Ni] Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Pain Management, 277,Yanta West Rd, Xian 710061, Shaanxi, Peoples R China.
   [Cui, Yi-Wei; Dong, Yu-Chen; Tang, Jie-Zhang; Bian, Yong-Qian; Li, Jing] Fourth Mil Med Univ, Tangdu Hosp, Dept Burn & Plast Surg, 1,Xinsi Rd, Xian 710000, Shaanxi, Peoples R China.
   [Li, Hang; Li, Xue-Yong] Xi An Jiao Tong Univ, Affiliated Hosp 2, Dept Burn Plast & Wound Repair Surg, 157,West Fifth Rd, Xian 710004, Shaanxi, Peoples R China.
   [Zhang, Hao] 927th Hosp Joint Logist Support Force, Dept Burn & Plast Surg, 3 Yushui Rd, Puer 665000, Yunnan, Peoples R China.
   [Wang, Wen-Xuan] Fourth Mil Med Univ, Xijing Hosp, Burn & Dermatol Surg, 127 Changle West Rd, Xian 710032, Shaanxi, Peoples R China.
C3 Air Force Medical University; Xi'an Jiaotong University; Air Force
   Medical University; Xi'an Jiaotong University; Air Force Medical
   University
RP Bian, YQ; Li, J (通讯作者)，Fourth Mil Med Univ, Tangdu Hosp, Dept Burn & Plast Surg, 1,Xinsi Rd, Xian 710000, Shaanxi, Peoples R China.; Li, XY (通讯作者)，Xi An Jiao Tong Univ, Affiliated Hosp 2, Dept Burn Plast & Wound Repair Surg, 157,West Fifth Rd, Xian 710004, Shaanxi, Peoples R China.
EM yongqianbian@163.com; lijing02@fmmu.edu.cn; lixueyong641123@163.com
FU Key R&D plan of Shaanxi Province [2024SF-YBXM-208]
FX This research was supported by the Key R&D plan of Shaanxi Province
   (number: 2024SF-YBXM-208).
CR Apelqvist Jan, 2017, J Wound Care, V26, pS1, DOI [10.12968/jowc.2017.26.sup3.s1, 10.12968/jowc.2017.26.Sup3.S1]
   Baldwin C, 2009, ANN PLAS SURG, V62, P92, DOI 10.1097/SAP.0b013e31817762fd
   Bayat M, 2006, J REHABIL RES DEV, V43, P219, DOI 10.1682/JRRD.2005.05.0089
   Bhardwaj H, 2026, INT J LOW EXTR WOUND, V25, P284, DOI 10.1177/15347346241228788
   Cao R, 2024, ADV SCI, V11, DOI 10.1002/advs.202302327
   Chen G, 2023, ADV SCI, V10, DOI 10.1002/advs.202303369
   Chen QQ, 2012, CAN J PHYSIOL PHARM, V90, P1611, DOI 10.1139/y2012-133
   Chen XQ, 2019, ACS BIOMATER SCI ENG, V5, P1762, DOI 10.1021/acsbiomaterials.8b01554
   Chen X, 2018, NEURON, V100, P799, DOI 10.1016/j.neuron.2018.09.046
   Davis J, 2012, DEV CELL, V23, P705, DOI 10.1016/j.devcel.2012.08.017
   Dong JY, 2020, INT WOUND J, V17, P1428, DOI 10.1111/iwj.13423
   Eid ES, 2022, CLIN EXP DERMATOL, V47, P1036, DOI 10.1111/ced.15138
   Formosa M, 2024, SAGE OPEN NURS, V10, DOI 10.1177/23779608241292839
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   He JH, 2021, CELL DEATH DIS, V12, DOI 10.1038/s41419-021-03481-6
   Holt JR, 2021, ELIFE, V10, DOI [10.7554/eLife.65415, 10.7554/eLife.65415.sa1, 10.7554/eLife.65415.sa2]
   Hsu CC, 2010, AM J PHYSIOL-CELL PH, V299, pC528, DOI 10.1152/ajpcell.00504.2009
   Hu YX, 2023, ADV SCI, V10, DOI 10.1002/advs.202303375
   Jakka VVSV, 2021, BIOMED RES INT, V2021, DOI 10.1155/2021/8847372
   Ji SZ, 2021, BURNS TRAUMA, V9, DOI 10.1093/burnst/tkab018
   Jin J, 2023, CELL PROLIFERAT, V56, DOI 10.1111/cpr.13493
   Kang HJ, 2019, AM J PHYSIOL-CELL PH, V316, pC92, DOI 10.1152/ajpcell.00346.2018
   Khalifa MO, 2023, BIOCHEM BIOPH RES CO, V667, P104, DOI 10.1016/j.bbrc.2023.05.042
   Knoedler S, 2023, FRONT IMMUNOL, V14, DOI 10.3389/fimmu.2023.1233800
   Lu F, 2011, ANN PLAS SURG, V66, P296, DOI 10.1097/SAP.0b013e3181ea1e9b
   Manabe T, 2021, INFLAMM REGEN, V41, DOI 10.1186/s41232-021-00176-5
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   McNulty AK, 2009, WOUND REPAIR REGEN, V17, P192, DOI 10.1111/j.1524-475X.2009.00460.x
   NEMLANDER A, 1983, TRANSPLANTATION, V36, P1, DOI 10.1097/00007890-198307000-00001
   Orsini EM, 2021, FRONT IMMUNOL, V12, DOI 10.3389/fimmu.2021.767319
   Pandit V, 2015, J MECH BEHAV BIOMED, V44, P173, DOI 10.1016/j.jmbbm.2015.01.012
   Peña OA, 2024, NAT REV MOL CELL BIO, V25, P599, DOI 10.1038/s41580-024-00715-1
   Ravindhran B, 2023, EXPERT REV MOL MED, V25, DOI 10.1017/erm.2023.24
   Shou KQ, 2017, BIOMED RES INT, V2017, DOI 10.1155/2017/7920265
   Smit TH, 2022, CURR OSTEOPOROS REP, V20, P127, DOI 10.1007/s11914-022-00728-9
   Taivanbat B, 2023, J DERMATOL SCI, V112, P54, DOI 10.1016/j.jdermsci.2023.10.002
   Wang SP, 2020, NAT COMMUN, V11, DOI 10.1038/s41467-020-16026-w
   Wilkes RP, 2007, TISSUE ENG, V13, P3003, DOI 10.1089/ten.2007.0036
   Yamashiro Toshifumi, 2023, Adv Exp Med Biol, V1436, P131, DOI 10.1007/5584_2023_773
   Yamashiro T, 2023, SKIN RES TECHNOL, V29, DOI 10.1111/srt.13262
   Zhang S, 2022, AUTOPHAGY, V18, P2229, DOI 10.1080/15548627.2021.2016231
   Zhu H, 2023, INT IMMUNOPHARMACOL, V123, DOI 10.1016/j.intimp.2023.110779
NR 42
TC 0
Z9 0
U1 2
U2 2
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 2321-3868
EI 2321-3876
J9 BURNS TRAUMA
JI Burns Trauma
PY 2026
VL 14
AR tkag007
DI 10.1093/burnst/tkag007
PG 18
WC Emergency Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Dermatology; Surgery
GA IG1CC
UT WOS:001770864300001
PM 42181011
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Drumm, C
   Creavin, B
   Previsic, IP
   O'Neill, M
   Larkin, J
   Mehigan, BJ
   Kavanagh, D
   Mccormick, P
   Kelly, ME
AF Drumm, Caroline
   Creavin, Ben
   Previsic, Iva Pranjic
   O'Neill, Maeve
   Larkin, John
   Mehigan, Brian J.
   Kavanagh, Dara
   Mccormick, Paul
   Kelly, Michael Eamon
TI The use of negative pressure wound therapy following stoma reversal: a
   systematic review and meta-analysis of randomized controlled trials
SO INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
LA English
DT Article
DE Negative pressure; NPWT; Stoma reversal; Colorectal surgery
ID SURGICAL SITE INFECTION; CLOSURE
AB IntroductionStoma reversal is a contaminated surgery with many patients experiencing significant wound complications that contribute to patient morbidity. It is believed that the use of prophylactic negative pressure wound therapy (NPWT) may enhance wound healing and help reduce the risk of developing surgical site infections (SSI). However, there is conflicting research regarding its effectiveness following stoma reversal. Our systematic review aims to evaluate the available randomized data to determine if the use of prophylactic NPWT after stoma reversal improves the duration of wound healing and reduces rates of postoperative complications.MethodsA comprehensive search of literature published up to January 2025 was conducted using the following databases: PubMed, Embase, Medline, and Cochrane Library. The included trials were randomized controlled trials that investigated the effect of NPWT following stoma reversal. The primary outcome was the time to complete wound healing. Secondary outcomes included the incidence of wound complications, SSI, hematomas, and the length of hospital stay.ResultsSix randomised control trials were included, with 332 patients, of which 171 of these underwent NPWT. There was a significant reduction in time to complete wound healing (OR - 2.53, 95% CI - 3.82 to - 1.24, p = 0.0001, I2 = 45%) and wound healing at 42 days (OR 0.36, 95% CI 0.14 - 0.88, p = 0.03, I2 = 0%) in the NPWT group. There was no significant difference in any wound complications (OR 0.72, 95% CI 0.23-2.28, p = 0.58, I2 = 42%), SSI rates (OR 0.95, 95% CI 0.27-3.29, p = 0.94, I2 = 38%) or haematoma rates (OR 0.21, 95% CI 0.03-1.27, p = 0.09, I2 = 0%) between the groups. There was no significant difference in length of stay (OR - 0.02, 95% CI - 1.21-1.18, p = 0.98, I2 = 66%).ConclusionThe use of NPWT after stoma reversal significantly reduces the time needed for complete wound healing while maintaining a comparable rate of wound complications and length of hospital stay. Therefore, NPWT may be valuable in optimizing postoperative recovery and enhancing patient outcomes.
C1 [Drumm, Caroline; Creavin, Ben; Previsic, Iva Pranjic; O'Neill, Maeve; Larkin, John; Mehigan, Brian J.; Mccormick, Paul; Kelly, Michael Eamon] St James Hosp, Dept Surg, Dublin, Ireland.
   [Kavanagh, Dara] Tallaght Univ Hosp, Dept Surg, Dublin, Ireland.
C3 Trinity College Dublin
RP Kelly, ME (通讯作者)，St James Hosp, Dept Surg, Dublin, Ireland.
EM Kellym11@tcd.ie
FU IReL Consortium
FX Open Access funding provided by the IReL Consortium.
CR [Anonymous], 2021, J Clin Epidemiol, V134, pA5, DOI [10.1016/j.jclinepi.2021.04.008, 10.1016/j.jclinepi.2021.04.008]
   Badia JM, 2017, J HOSP INFECT, V96, P1, DOI 10.1016/j.jhin.2017.03.004
   Banerjee A, 1997, DIS COLON RECTUM, V40, P993, DOI 10.1007/BF02051210
   Boland PA, 2021, IRISH J MED SCI, V190, P261, DOI 10.1007/s11845-020-02283-7
   Carrano FM, 2021, BJS OPEN, V5, DOI 10.1093/bjsopen/zrab116
   Chow A, 2009, INT J COLORECTAL DIS, V24, P711, DOI 10.1007/s00384-009-0660-z
   Curran T, 2019, COLORECTAL DIS, V21, P110, DOI 10.1111/codi.14350
   Gachabayov M, 2019, TECH COLOPROCTOL, V23, P207, DOI 10.1007/s10151-019-01952-9
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Kang SI, 2023, ANN SURG TREAT RES, V105, P126, DOI 10.4174/astr.2023.105.3.126
   Kisielewski M, 2024, Incisional negative pressure wound therapy versus primary wound suturing after intestinal ostomy closure: a systematic review and meta-analysis
   Kojima K, 2021, BMC SURG, V21, DOI 10.1186/s12893-021-01446-2
   Low EZ, 2022, INT J COLORECTAL DIS, V37, P1215, DOI 10.1007/s00384-022-04153-3
   Luo JL, 2024, MEDICINE, V103, DOI 10.1097/MD.0000000000039477
   Rondelli F, 2018, INT J SURG, V52, P208, DOI 10.1016/j.ijsu.2018.02.027
   Sherman KL, 2017, CLIN COLON RECT SURG, V30, P172, DOI 10.1055/s-0037-1598157
   Taylor C, 2011, EUR J ONCOL NURS, V15, P59, DOI 10.1016/j.ejon.2010.06.002
   Tiang T, 2024, ANZ J SURG, V94, P1627, DOI 10.1111/ans.18941
   Uchino M, 2016, DIGEST SURG, V33, P449, DOI 10.1159/000446550
   Vidya R, 2023, PRS-GLOB OPEN, V11, DOI 10.1097/GOX.0000000000005488
   Wierdak M, 2021, TECH COLOPROCTOL, V25, P185, DOI 10.1007/s10151-020-02372-w
   Zhu JJ, 2023, J INVEST SURG, V36, DOI 10.1080/08941939.2023.2175079
NR 22
TC 3
Z9 3
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0179-1958
EI 1432-1262
J9 INT J COLORECTAL DIS
JI Int. J. Colorectal Dis.
PD MAR 20
PY 2025
VL 40
IS 1
AR 73
DI 10.1007/s00384-025-04865-2
PG 9
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 0IZ4Z
UT WOS:001448512600001
PM 40111521
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Yammine, K
   Abdallah, R
   Stiban, S
   Helou, M
   Hayek, F
   Assi, C
AF Yammine, Kaissar
   Abdallah, Ralph
   Stiban, Sonia
   Helou, Mariana
   Hayek, Fady
   Assi, Chahine
TI Monitoring negative pressure wound therapy for diabetic foot ulcers
   using WhatsApp
SO JOURNAL OF TISSUE VIABILITY
LA English
DT Article
DE Diabetic foot ulcer; Negative wound pressure therapy; WhatsApp; Wound
   healing
ID RELIABILITY; AMPUTATION; MORTALITY
AB Foot complications of patients with diabetes could lead to amputations and early death. Diabetic foot ulcers (DFU) are usually difficult to treat and impose huge financial burden. Monitoring wound progress is the mainstay of any treatment and alternatives to face-to-face consultations such as tele-medicine have been proposed. Very few papers explored the utility and effectiveness of monitoring DFU through instant messaging application such as WhatsApp. The aim of this study is to evaluate the validity of WhatsApp in monitoring diabetic wounds treated with negative pressure wound therapy (NPWT). Twenty-two patients were prospectively recruited. All patients had an initial face-to-face consultation and debridement. Dressings were changed twice per week at patient's residence and media files were sent by the wound nurse via Short Message Service (SMS). A subsequent face to face consultation was scheduled whenever a complication was suspected. The primary outcomes were the percentages of accurate cases a) where a new or recurrent infection was suspected, and a b) where a debridement was thought to be needed. Complete healing of the defect using NPWT was achieved in 10 patients and a skin graft procedure was needed in another 4 patients. Five patients needed further surgical debridement. Failure to heal was observed in 3 patients. Out of the seven cases where a new infection was suspected, five (71.5%) were confirmed on face-toface consultation. No confirmed cases of infection were observed during follow-up for those estimated as clean. Out of the 11 cases where debridement was favored based on WhatsApp media files, confirmation of a needed debridement was recorded in 8 (73%) cases. NPWT monitoring of for diabetic foot and leg ulcers using WhatsApp application was found to be an excellent method to document and track the wound process and complications. The excellent specificity and high sensibility should encourage for common use by healthcare. The results of this study could be also valuable for patients living in rural areas and in case of future pandemics.
C1 [Yammine, Kaissar; Assi, Chahine] Lebanese Amer Univ, Med Ctr, Rizk Hosp, Sch Med,Dept Orthoped Surg, Beirut, Lebanon.
   [Yammine, Kaissar; Stiban, Sonia] Lebanese Amer Univ, Rizk Hosp, Diabetic Foot Clin, Med Ctr, Beirut, Lebanon.
   [Abdallah, Ralph] Univ Toronto, Fac Arts & Sci, Toronto, ON, Canada.
   [Helou, Mariana] Lebanese Amer Univ, Med Ctr, Rizk Hosp, Sch Med,Dept Emergency Med, Beirut, Lebanon.
   [Hayek, Fady] Lebanese Amer Univ, Med Ctr, Rizk Hosp, Sch Med,Div Vasc Surg,Dept Gen Surg, Beirut, Lebanon.
C3 Lebanese American University; Lebanese American University; University
   of Toronto; Lebanese American University; Lebanese American University
RP Yammine, K (通讯作者)，Lebanese Amer Univ, Med Ctr, Rizk Hosp, Sch Med,Dept Orthoped Surg, Beirut, Lebanon.
EM cesaryam@gmail.com
RI helou, mariana/AAC-6267-2020; Assi, Chahine/AAD-7388-2020; Yammine,
   Kaissar/L-5994-2019
OI helou, mariana/0000-0001-8626-8988; Abdallah, Ralph/0009-0001-0529-8040;
   Yammine, Kaissar/0000-0003-0094-9892
CR Al Omar M, 2020, PHARM PRACT-GRANADA, V18, DOI [10.18549/PharmPract.2020.2.1841, 10.18549/pharmpract.2020.2.1841]
   Armstrong DG, 2017, NEW ENGL J MED, V376, P2367, DOI 10.1056/NEJMra1615439
   Ghanassia E, 2008, DIABETES CARE, V31, P1288, DOI 10.2337/dc07-2145
   Jeihooni Ali Khani, 2019, Indian J Endocrinol Metab, V23, P609, DOI [10.4103/ijem.ijem_439_19, 10.4103/ijem.IJEM_439_19]
   Kaka AS, 2023, J FOOT ANKLE RES, V16, DOI 10.1186/s13047-023-00610-6
   Kelahmetoglu O, 2020, INT WOUND J, V17, P1424, DOI 10.1111/iwj.13416
   Khoo SS, 2023, J HAND SURG-EUR VOL, V48, P419, DOI 10.1177/17531934231151202
   Paryavi E, 2016, J PEDIATR ORTHOPED, V36, P483, DOI 10.1097/BPO.0000000000000477
   Sartori AC, 2020, TELEMED E-HEALTH, V26, P1526, DOI 10.1089/tmj.2019.0305
   Singh N, 2005, JAMA-J AM MED ASSOC, V293, P217, DOI 10.1001/jama.293.2.217
   Stahl I, 2019, PEDIATR EMERG CARE, V35, P403, DOI 10.1097/PEC.0000000000001211
   Stahl I, 2017, SPINE J, V17, P161, DOI 10.1016/j.spinee.2016.08.021
   Téot L, 2020, INT J LOW EXTR WOUND, V19, P197, DOI 10.1177/1534734619894485
   Thorud JC, 2016, J FOOT ANKLE SURG, V55, P591, DOI 10.1053/j.jfas.2016.01.012
   van Dieren S, 2010, EUR J CARDIOV PREV R, V17, pS3, DOI 10.1097/01.hjr.0000368191.86614.5a
   Yammine Kaissar, 2022, Foot (Edinb), V50, P101872, DOI [10.1016/j.foot.2021.101872, 10.1016/j.foot.2021.101872]
   Yammine K, 2020, J VASC SURG, V72, P2197, DOI 10.1016/j.jvs.2020.07.086
NR 17
TC 3
Z9 4
U1 1
U2 11
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0965-206X
EI 1876-4746
J9 J TISSUE VIABILITY
JI J. Viab.
PD FEB
PY 2024
VL 33
IS 1
BP 1
EP 4
DI 10.1016/j.jtv.2024.01.001
EA MAR 2024
PG 4
WC Dermatology; Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Dermatology; Nursing
GA OB7G1
UT WOS:001204859200001
PM 38220561
DA 2026-07-24
ER

PT J
AU Kosugi, K
   Zenke, Y
   Sato, N
   Hamada, D
   Ando, K
   Okada, Y
   Yamanaka, Y
   Sakai, A
AF Kosugi, Kenji
   Zenke, Yukichi
   Sato, Naohito
   Hamada, Daishi
   Ando, Kohei
   Okada, Yasuaki
   Yamanaka, Yoshiaki
   Sakai, Akinori
TI Potential of Continuous Local Antibiotic Perfusion Therapy for
   Fracture-Related Infections
SO INFECTIOUS DISEASES AND THERAPY
LA English
DT Article
DE Continuous local antibiotic perfusion; Fracture-related infections;
   Gentamicin; Negative-pressure wound therapy
ID GENTAMICIN; PROPHYLAXIS; BEADS; INJECTION; CEMENT
AB Introduction Fracture-related infections (FRIs) are challenging for orthopedic surgeons, as conventional surgical treatment and systemic antimicrobial therapy cannot completely control local infections. Continuous local antibiotic perfusion (CLAP) is a novel and innovative therapy for bone and soft-tissue infections, and is expected to eradicate biofilms by maintaining a sustained high concentration of antimicrobial agents at the infected site. If CLAP therapy can eradicate infection even in cases with implants while preserving the implants, it would be an ideal and effective treatment for local refractory infections. This study aimed to evaluate the usefulness of novel CLAP therapy for FRIs. Methods Nine patients treated with CLAP therapy were retrospectively analyzed. The mean age was 65.9 (43-82) years, and the mean follow-up period was 14.9 (6-45) months. In all cases, the infected sites were related to the lower extremities (tibia, n = 6; fibula, n = 1; hip joint, n = 1; foot, n = 1). All patients underwent similar procedures for this therapy combined with negative-pressure wound therapy after thorough irrigation and debridement of infected tissues. Results The pathogens identified were Staphylococcus aureus (methicillin-resistant S. aureus, n = 5; methicillin-susceptible S. aureus, n = 1), Pseudomonas aeruginosa (n = 3), Enterococcus faecalis (n = 2), Corynebacterium (n = 1), and Enterobacter (n = 1); pathogens were not detected in one case. The mean duration of CLAP was 17.0 (7-35) days. In all cases, implants were preserved until bone union was achieved. Five cases relapsed; however, infection was finally suppressed in all cases by repeating this method. No side effects were observed. Conclusion This novel case series presents treatment outcomes using CLAP therapy for FRIs. This method has the potential to control the infection without removing the implants, because of the sustained high concentration of antimicrobial agents at the infected site, and could be a valuable treatment option for refractory FRIs with implants, in which bone union has not been achieved.
C1 [Kosugi, Kenji; Okada, Yasuaki; Yamanaka, Yoshiaki; Sakai, Akinori] Univ Occupat & Environm Hlth, Dept Orthopaed Surg, Kitakyushu, Fukuoka, Japan.
   [Zenke, Yukichi; Sato, Naohito; Hamada, Daishi; Ando, Kohei] Univ Occupat & Environm Hlth, Dept Emergency Med, Yahatanishi Ku, 1-1 Iseigaoka, Kitakyushu, Fukuoka 8078555, Japan.
C3 University of Occupational & Environmental Health - Japan; University of
   Occupational & Environmental Health - Japan
RP Zenke, Y (通讯作者)，Univ Occupat & Environm Hlth, Dept Emergency Med, Yahatanishi Ku, 1-1 Iseigaoka, Kitakyushu, Fukuoka 8078555, Japan.
EM k.kosugi0924@gmail.com; ukichi.drz@gmail.com; naotu0722@yahoo.co.jp;
   olewaeconaotoco0608@gmail.com; koheiando@mac.com; 0713yasuaki@gmail.com;
   yamanaka@med.uoeh-u.ac.jp; a-sakai@med.uoeh-u.ac.jp
OI Kosugi, Kenji/0000-0003-1183-2921; Ando, Kohei/0000-0002-6623-477X;
   Sakai, Akinori/0000-0002-6023-5536
CR Anagnostakos K, 2009, ACTA ORTHOP, V80, P193, DOI 10.3109/17453670902884700
   Arciola CR, 2018, NAT REV MICROBIOL, V16, P397, DOI 10.1038/s41579-018-0019-y
   Badha Vajra, 2019, J Bone Jt Infect, V4, P1, DOI [10.7150/jbji.29711, 10.7150/jbji.29711]
   Berkes M, 2010, J BONE JOINT SURG AM, V92A, P823, DOI 10.2106/JBJS.I.00470
   Castaneda P, 2016, CLIN ORTHOP RELAT R, V474, P1659, DOI 10.1007/s11999-016-4700-z
   Cavanaugh DL, 2009, J BONE JOINT SURG AM, V91A, P1907, DOI 10.2106/JBJS.G.01237
   Ceri H, 1999, J CLIN MICROBIOL, V37, P1771, DOI 10.1128/JCM.37.6.1771-1776.1999
   Conway J, 2014, BONE JOINT J, V96B, P1349, DOI 10.1302/0301-620X.96B10.33799
   Costerton JW, 1999, SCIENCE, V284, P1318, DOI 10.1126/science.284.5418.1318
   Craig WA, 1998, CLIN INFECT DIS, V26, P1, DOI 10.1086/516284
   Depypere M, 2020, J ORTHOP TRAUMA, V34, P30, DOI 10.1097/BOT.0000000000001626
   Govaert GAM, 2020, J ORTHOP TRAUMA, V34, P8, DOI 10.1097/BOT.0000000000001614
   Hashmi MA, 2004, J BONE JOINT SURG BR, V86B, P269, DOI 10.1302/0301-620X.86B2.14011
   Hayward RS, 2018, BRIT J CLIN PHARMACO, V84, P223, DOI 10.1111/bcp.13439
   Himeno D, 2022, J ORTHOP SCI, V27, P272, DOI 10.1016/j.jos.2020.11.010
   Lawing CR, 2015, J BONE JOINT SURG AM, V97A, P1844, DOI 10.2106/JBJS.O.00072
   Li SP, 2019, EUR SPINE J, V28, P2972, DOI 10.1007/s00586-019-06143-6
   Lovallo J, 2014, J SHOULDER ELB SURG, V23, P1272, DOI 10.1016/j.jse.2013.12.016
   Metsemakers WJ, 2018, INJURY, V49, P505, DOI 10.1016/j.injury.2017.08.040
   Metsemakers WJ, 2016, INJURY, V47, P595, DOI 10.1016/j.injury.2016.01.019
   Metsemakers WJ, 2017, INT ORTHOP, V41, P2457, DOI 10.1007/s00264-017-3607-y
   Mottola C, 2016, BMC MICROBIOL, V16, DOI 10.1186/s12866-016-0737-0
   Reiter KC, 2013, J MED MICROBIOL, V62, P394, DOI 10.1099/jmm.0.048678-0
   Saeed K, 2019, J ORTHOP RES, V37, P1007, DOI 10.1002/jor.24229
   Sweet FA, 2011, SPINE, V36, P2084, DOI 10.1097/BRS.0b013e3181ff2cb1
   Thakore Rachel V, 2015, J Clin Orthop Trauma, V6, P220, DOI [10.1016/j.jcot.2015.04.004, 10.1016/j.jcot.2015.04.004]
   Trampuz A, 2006, INJURY, V37, P59, DOI 10.1016/j.injury.2006.04.010
   Tschudin-Sutter S, 2016, CLIN MICROBIOL INFEC, V22, DOI 10.1016/j.cmi.2016.01.004
   WALENKAMP GHIM, 1986, CLIN ORTHOP RELAT R, P171
   Wininger DA, 1996, ANTIMICROB AGENTS CH, V40, P2675, DOI 10.1128/AAC.40.12.2675
   Yarboro SR, 2007, J BONE JOINT SURG AM, V89A, P929, DOI 10.2106/JBJS.F.00919
   Zalavras CG, 2004, CLIN ORTHOP RELAT R, P86, DOI 10.1097/01.blo.0000143571.18892.8d
NR 32
TC 23
Z9 30
U1 0
U2 3
PU SPRINGER LONDON LTD
PI LONDON
PA 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND
SN 2193-8229
EI 2193-6382
J9 INFECT DIS THER
JI Infect. Dis. Ther.
PD AUG
PY 2022
VL 11
IS 4
BP 1741
EP 1755
DI 10.1007/s40121-022-00653-5
EA MAY 2022
PG 15
WC Infectious Diseases
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases
GA 3I6QB
UT WOS:000798472700001
PM 35596921
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Masters, J
   Cook, J
   Achten, J
   Costa, ML
AF Masters, J.
   Cook, J.
   Achten, J.
   Costa, M. L.
TI A feasibility study of standard dressings versus negative-pressure wound
   therapy in the treatment of adult patients having surgical incisions for
   hip fractures: the WHISH randomized controlled trial
SO BONE & JOINT JOURNAL
LA English
DT Article
ID TRAUMA EVALUATION ONE; ABRIDGED PROTOCOL; SCREW FIXATION; X-BOLT; WHITE;
   INFECTION; HEMIARTHROPLASTY; COMPLICATIONS; SURGERY; COHORT
AB Aims
   This study sought to compare the rate of deep surgical site infection (SSI), as measured by the Centers for Disease Control and Prevention (CDC) definition, after surgery for a fracture of the hip between patients treated with standard dressings and those treated with incisional negative pressure wound therapy (iNPWT). Secondary objectives included determining the rate of recruitment and willingness to participate in the trial.
   Methods
   The study was a two-arm multicentre randomized controlled feasibility trial that was embedded in the World Hip Trauma Evaluation cohort study. Any patient aged > 65 years having surgery for hip fracture at five recruitment centres in the UK was considered to be eligible. They were randomly allocated to have either a standard dressing or iNPWT after closure of the wound. The primary outcome measure was deep SSI at 30 and 90 days, diagnosed according to the CDC criteria. Secondary outcomes were: rate of recruitment; further surgery within 120 days; health-related quality of life (HRQoL) using the EuroQol five-level five-dimension questionnaire (EQ-5D-5L); and related complications within 120 days as well as mobility and residential status at this time.
   Results
   A total of 462 valid randomizations were carried out (232 and 230 in the standard dressing and iNPWT groups, respectively). In the standard dressing group, 14 of 218 patients (6.4%) developed deep SSI. In the iNPWT group, four of 214 patients (1.9%) developed deep SSI. This gives a total rate of SSI of 4.2% (95% confidence interval (CI) 2.7% to 6.5%). Patients and surgeons were willing to participate in the study with 462 patients being recruited from a possible 749 (62.3%).
   Conclusion
   The rate of deep SSI 30 days after surgery for a fracture of the hip was 4%, which makes a study comparing the clinical effectiveness of standard dressings and iNPWT feasible.
C1 [Masters, J.; Cook, J.; Achten, J.; Costa, M. L.] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford, England.
C3 University of Oxford
RP Masters, J (通讯作者)，Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Oxford, England.
EM james.masters@ndorms.ox.ac.uk
RI Masters, James/U-8764-2019; Cook, Jonathan/D-3648-2015; Achten,
   Juul/KUD-8515-2024
OI Masters, James/0000-0001-9663-8858; Cook, Jonathan/0000-0002-4156-6989;
   Costa, Matthew/0000-0003-3644-1388; Achten, Juul/0000-0002-8857-5743
FU Royal College of Surgeons of England/Dunhill Medical Trust research
   training fellowship; Smith Nephew; NIHR Oxford Biomedical Research
   Centre
FX J. Masters and J. Cook report institutional grants (paid to University
   of Oxford) from the Royal College of Surgeons of England/Dunhill Medical
   Trust research training fellowship, Smith & Nephew (device supply), and
   the NIHR Oxford Biomedical Research Centre (research infrastructure
   support), all related to this study. M. Costa reports institutional
   research grant funding (paid to University of Oxford) from the National
   Institute for Health Research (NIHR), the European Union (EU), the Royal
   College of Surgeons (RCS) England, and Smith & Nephew, not related to
   this study.
CR [Anonymous], 2021, INFECT CONT HOSP EP
   [Anonymous], 2018, National Hip Fracture Database Annual Report
   [Anonymous], 2021, IRAS INTEGRATED RES
   [Anonymous], 2021, EQ 5D 5L VAL CROSSW
   [Anonymous], 2005, MENTAL CAPACITY ACT
   Brown LD, 2001, STAT SCI, V16, P101, DOI 10.1214/ss/1009213286
   Costa ML, 2020, JAMA-J AM MED ASSOC, V323, P519, DOI 10.1001/jama.2020.0059
   Costa ML, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2016-011679
   Edwards C, 2008, J BONE JOINT SURG BR, V90B, P770, DOI 10.1302/0301-620X.90B6.20194
   Falls and Fragility Fracture Audit Programme (FFFAP), 2015, NATL HIP FRACTURE DA
   Fernandez MA, 2018, BMJ OPEN, V8, DOI 10.1136/bmjopen-2018-023301
   Griffin XL, 2016, BONE JOINT J, V98B, P686, DOI 10.1302/0301-620X.98B5.37350
   Griffin XL, 2013, BONE JOINT RES, V2, P210, DOI 10.1302/2046-3758.210.2000186
   Griffin XL, 2013, BONE JOINT RES, V2, P206, DOI 10.1302/2046-3758.210.2000183
   Griffin XL, 2012, BONE JOINT RES, V1, P310, DOI 10.1302/2046-3758.111.2000127
   Griffin XL, 2018, BMJ OPEN, V8, DOI 10.1136/bmjopen-2017-019944
   Hansson S, 2015, INJURY, V46, P2206, DOI 10.1016/j.injury.2015.07.024
   Haywood KL, 2014, BONE JOINT J, V96B, P1016, DOI 10.1302/0301-620X.96B8.33766
   Horan TC, 2008, AM J INFECT CONTROL, V36, P309, DOI 10.1016/j.ajic.2008.03.002
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Masters JPM, 2018, BMJ OPEN, V8, DOI 10.1136/bmjopen-2017-020632
   Metcalfe D, 2019, BONE JOINT J, V101B, P708, DOI 10.1302/0301-620X.101B6.BJJ-2018-1623.R1
   Metcalfe D, 2019, BMC MED RES METHODOL, V19, DOI 10.1186/s12874-019-0753-5
   Pauser J, 2016, INT WOUND J, V13, P663, DOI 10.1111/iwj.12344
   Rennie D, 2001, JAMA-J AM MED ASSOC, V285, P2006, DOI 10.1001/jama.285.15.2006
   Roche JJW, 2005, BMJ-BRIT MED J, V331, P1374, DOI 10.1136/bmj.38643.663843.55
   Saklad M., 1941, ANESTHESIOLOGY, V2, P281, DOI DOI 10.1097/00000542-194105000-00004
   Sims AL, 2016, BONE JOINT RES, V5, P18, DOI 10.1302/2046-3758.51.2000473
   Theodorides AA, 2011, INJURY, V42, pS28, DOI 10.1016/S0020-1383(11)70130-9
   van Hout B, 2012, VALUE HEALTH, V15, P708, DOI 10.1016/j.jval.2012.02.008
   Webster J, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub4
   Westberg M, 2013, ACTA ORTHOP, V84, P124, DOI 10.3109/17453674.2013.775044
NR 32
TC 18
Z9 20
U1 0
U2 6
PU BRITISH EDITORIAL SOC BONE & JOINT SURGERY
PI LONDON
PA 22 BUCKINGHAM STREET, LONDON WC2N 6ET, ENGLAND
SN 2049-4394
J9 BONE JOINT J
JI Bone Joint J.
PD APR
PY 2021
VL 103B
IS 4
BP 755
EP 761
DI 10.1302/0301-620X.103B4.BJJ-2020-1603.R1
PG 7
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA RI5GM
UT WOS:000636935700023
PM 33789474
DA 2026-07-24
ER

PT J
AU Svensson-Björk, R
   Hasselmann, J
   Acosta, S
AF Svensson-Bjork, Robert
   Hasselmann, Julien
   Acosta, Stefan
TI Evaluation of inguinal vascular surgical scars treated with closed
   incisional negative pressure wound therapy using three-dimensional
   digital imaging-A randomized controlled trial on bilateral incisions
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID QUALITY-OF-LIFE; ANTIBIOTIC-PROPHYLAXIS; INFLAMMATORY RESPONSE;
   ASSESSMENT SCALE; SITE INFECTION; LINEAR SCARS; SURGERY; PATIENT;
   METAANALYSIS; MANAGEMENT
AB Purpose of the investigation: Scar formation is an important, permanent surrogate marker for wound healing. The main aim of this randomized trial was to evaluate the effects of incisional negative pressure wound therapy (iNPWT) on scar formation in uncomplicated wound healing with 3-dimensional (3D) digital imaging. Basic procedures: Patients undergoing bilateral inguinal incisions after vascular surgery were randomized to receive iNPWT and standard dressing on separate sides. The incisional scars were documented at a median time of 808 days (range 394-1194) after surgery with 3D photography, which were objectively evaluated by two plastic surgeons using the Stony Brook scar evaluation scale (SBSES) and a 10-point graded numeric ranking scale (NRS10). Subjective evaluation was performed with the patient observer scar assessment scale (POSAS). Patients with surgical site infection or other wound complications were excluded to minimize bias. The p-values were calculated using McNemar's and Wilcoxon signed-rank test for paired nominal and paired continuous data, respectively. Main findings: Among 33 patients, 32 patients had undergone endovascular aortic repair (EVAR) and 31 patients had transverse inguinal incisions. Objective and subjective scar evaluation showed no difference between iNPWT and standard dressing. In objective scorings, 18.8 and 21.9% received the highest possible SBSES total score in the iNPWT and standard dressing groups, while 43.8 and 37.5% received the highest possible NRS10 score, respectively. The inter-rater reliability between the two assessors for SBSES total score and NRS10 showed an intra-class correlation (ICC) of 0.78 and 0.68 for NPWT and 0.70 and 0.77 for traditional dressing, respectively. Principal conclusion: The present randomized trial showed that iNPWT and standard dressings on closed transverse inguinal incisions after EVAR resulted in equal subtle scar formation. Objective scar evaluation with 3D images showed good inter-rater agreement.
C1 [Svensson-Bjork, Robert; Hasselmann, Julien; Acosta, Stefan] Lund Univ, Dept Clin Sci, Ruth Lundskogs G 10, S-20502 Malmo, Sweden.
   [Svensson-Bjork, Robert; Hasselmann, Julien; Acosta, Stefan] Skane Univ Hosp, Dept Cardiothorac & Vasc Surg, Vasc Ctr, Malmo, Sweden.
C3 Lund University; Lund University; Skane University Hospital
RP Acosta, S (通讯作者)，Lund Univ, Dept Clin Sci, Ruth Lundskogs G 10, S-20502 Malmo, Sweden.
EM Stefan.acosta@med.lu.se
RI Hasselmann, Julien/C-1586-2015; Acosta, Stefan/JAX-3225-2023;
   Hasselmann, Julien/C-1586-2015
OI Acosta, Stefan/0000-0002-3225-0798; Svensson-Björk,
   Robert/0000-0003-1907-9022; Hasselmann, Julien/0000-0003-4453-0292
FU Hulda Almroth Foundation
FX The Hulda Almroth Foundation.
CR Ashcroft GS, 1997, J INVEST DERMATOL, V108, P430, DOI 10.1111/1523-1747.ep12289705
   Ayoub A, 2011, CLEFT PALATE-CRAN J, V48, P379, DOI 10.1597/10-057
   Baum CL, 2005, DERMATOL SURG, V31, P674
   Bayat A, 2005, BRIT J PLAST SURG, V58, P28, DOI 10.1016/j.bjps.2004.04.024
   Collins LK, 2017, FACIAL PLAST SURG, V33, P97, DOI [10.1055/s-0036-1597684, 10.1055/5-0036-1597684, 10.1055/s-0036-1597684]
   Cook CE, 2008, J MAN MANIP THER, V16, p82E, DOI 10.1179/jmt.2008.16.4.82E
   Delavary BM, 2012, J PLAST SURG HAND SU, V46, P95, DOI 10.3109/2000656X.2012.669184
   Draaijers LJ, 2004, PLAST RECONSTR SURG, V113, P1960, DOI 10.1097/01.PRS.0000122207.28773.56
   Duncan JAL, 2006, PLAST RECONSTR SURG, V118, P909, DOI 10.1097/01.prs.0000232378.88776.b0
   Edwards R, 2004, CURR OPIN INFECT DIS, V17, P91, DOI 10.1097/00001432-200404000-00004
   Eisenhardt SU, 2012, J PLAST RECONSTR AES, V65, P640, DOI 10.1016/j.bjps.2011.11.037
   Gurtner GC, 2011, ANN SURG, V254, P217, DOI 10.1097/SLA.0b013e318220b159
   Hasselmann J, 2015, Surgical Science, V06, P562, DOI [10.4236/ss.2015.612080, DOI 10.4236/SS.2015.612080]
   Hasselmann J, 2015, VASC ENDOVASC SURG, V49, P129, DOI 10.1177/1538574415600531
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Kantor J, 2017, JAMA DERMATOL, V153, P55, DOI 10.1001/jamadermatol.2016.3757
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Kuang RX, 2016, ANN PLAS SURG, V76, P388, DOI 10.1097/SAP.0000000000000654
   Lemperle G, 2014, PLAST RECONSTR SURG, V134, P1424, DOI 10.1097/01.prs.0000438462.13840.21
   Limongelli P, 2017, INT WOUND J, V14, P960, DOI 10.1111/iwj.12739
   Loveluck John, 2016, Eplasty, V16, pe20
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Matthews H, 2017, PSYCHO-ONCOLOGY, V26, P1860, DOI 10.1002/pon.4397
   MCHORNEY CA, 1995, QUAL LIFE RES, V4, P293, DOI 10.1007/BF01593882
   Sandmann W, 2016, EUR J VASC ENDOVASC, V52, P263, DOI 10.1016/j.ejvs.2016.04.026
   Semsarzadeh NN, 2015, PLAST RECONSTR SURG, V136, P592, DOI 10.1097/PRS.0000000000001519
   Singer AJ, 2007, PLAST RECONSTR SURG, V120, P1892, DOI 10.1097/01.prs.0000287275.15511.10
   Singer AJ, 2002, WOUND REPAIR REGEN, V10, P372, DOI 10.1046/j.1524-475X.2002.10606.x
   Sorensen LT, 2012, ANN SURG, V255, P1069, DOI 10.1097/SLA.0b013e31824f632d
   Suh HSP, 2016, PLAST RECONSTR SURG, V138, P1333, DOI 10.1097/PRS.0000000000002765
   Swinnen J, 2010, ANN VASC SURG, V24, P336, DOI 10.1016/j.avsg.2009.07.020
   Turtiainen J, 2010, SCAND J SURG, V99, P167, DOI 10.1177/145749691009900312
   Valente JH, 2014, ADV SKIN WOUND CARE, V27, P13, DOI 10.1097/01.ASW.0000439060.79822.b3
   Valente JH, 2012, ADV SKIN WOUND CARE, V25, P119, DOI 10.1097/01.ASW.0000412907.43335.a2
   van de Kar AL, 2005, PLAST RECONSTR SURG, V116, P514, DOI 10.1097/01.prs.0000172982.43599.d6
   van Zuijlen PPM, 2002, PLAST RECONSTR SURG, V109, P1108, DOI 10.1097/00006534-200203000-00052
   Vercelli S, 2015, INT J REHABIL RES, V38, P279, DOI 10.1097/MRR.0000000000000134
   Wilhelmi BJ, 1999, PLAST RECONSTR SURG, V104, P208, DOI 10.1097/00006534-199907000-00032
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   WILSON APR, 1986, LANCET, V1, P311
NR 40
TC 12
Z9 12
U1 0
U2 4
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JAN-FEB
PY 2018
VL 26
IS 1
BP 77
EP 86
DI 10.1111/wrr.12615
PG 10
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA GD2CV
UT WOS:000430308600188
PM 29381241
DA 2026-07-24
ER

PT J
AU Parrett, BM
   Matros, E
   Pribaz, JJ
   Orgill, DP
AF Parrett, BM
   Matros, E
   Pribaz, JJ
   Orgill, DP
TI Lower extremity trauma: Trends in the management of soft-tissue
   reconstruction of open tibia-fibula fractures
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article; Proceedings Paper
CT 21st Annual Meeting of the
   American-Society-for-Reconstructive-Microsurgery
CY JAN 15-18, 2005
CL Fajardo, PR
SP Amer Soc Reconstruct Microsurg
ID ISLAND FLAP; EXPERIENCE; EVOLUTION; COVERAGE; DEFECTS; THERAPY; ANKLE
AB Background: Open lower leg fractures With exposed bone or tendon continue to be challenging for plastic surgeons. Microvascular free-tissue transfer increases the ability to close wounds, transfer vascularized bone, and prevent amputation, yet remains a complex, invasive procedure with significant complication rates, donor-site morbidity, and failure rates. This review documents the changing treatment protocol in the authors' institution for these injuries.
   Methods: Two hundred ninety consecutive open tibia-fibula fractures over a 12-year period (1992 to 2003) were retrospectively reviewed and methods and outcomes were compared by grouping the fractures into 4-year intervals.
   Results: The number of open lower extremity fractures increased, whereas the distribution of Gustilo grade I to III fractures remained unchanged. Overall, free-tissue transfer was performed less frequently and constituted 20 percent of reconstructions in period 1 (1992 to 1995), 11 percent in period 2 (1996 to 1999), and 5 percent in period 3 (2000 to 2003). For the most severe fractures, Gustilo grade III, free-flap reconstruction has decreased significantly, constituting 42 percent, 26 percent, and 11 percent of procedures in periods 1, 2, and 3, respectively. Local flaps for grade III fractures have remained relatively constant throughout the study. In contrast, local wound care for grade III fractures, including skin grafts, delayed primary closures, and secondary intention closures has significantly increased from 22 percent to 49 percent of reconstructions from periods 1 through 3. In 1997, the authors began to use the vacuum-assisted closure device and now use it in nearly half of all open fractures. Despite this trend, there has been no change in infection, amputation, or malunion/nonunion rates and a decrease in reoperation rate with at least 1-year follow-up.
   Conclusions: These results demonstrate a change in practice, with a trend down the reconstructive ladder, currently using fewer free flaps and more delayed closures and skin grafts with frequent use of the vacuum-assisted closure sponge. Possible reasons for this change are a better understanding of lower leg vascular anatomy and better use of improved Wound care technology.
C1 Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Plast & Reconstruct Surg, Boston, MA 02478 USA.
C3 Harvard University; Harvard Medical School; Harvard University Medical
   Affiliates; Brigham & Women's Hospital
RP Parrett, BM (通讯作者)，Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Plast & Reconstruct Surg, 75 Francis St, Boston, MA 02478 USA.
EM dorgill@partners.org
RI Orgill, Dennis/H-7596-2019
OI Orgill, Dennis/0000-0002-8279-7310
CR ALDEA PA, 1986, CLIN PLAST SURG, V13, P549
   Almeida MF, 2002, PLAST RECONSTR SURG, V109, P583, DOI 10.1097/00006534-200202000-00027
   Baumeister SP, 2003, PLAST RECONSTR SURG, V112, P129, DOI 10.1097/01.PRS.0000066167.68966.66
   Beck JB, 2003, ANN PLAS SURG, V50, P631, DOI 10.1097/01.SAP.0000054185.22788.0F
   Benacquista T, 1996, PLAST RECONSTR SURG, V98, P834, DOI 10.1097/00006534-199610000-00013
   BYRD HS, 1985, PLAST RECONSTR SURG, V76, P719, DOI 10.1097/00006534-198511000-00011
   BYRD HS, 1981, PLAST RECONSTR SURG, V68, P73, DOI 10.1097/00006534-198107000-00015
   Cavadas PC, 2003, PLAST RECONSTR SURG, V111, P837, DOI 10.1097/01.PRS.0000039573.08861.94
   Chen SL, 2002, PLAST RECONSTR SURG, V110, P1664, DOI 10.1097/00006534-200212000-00007
   CIERNY G, 1983, CLIN ORTHOP RELAT R, V178, P55
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Dickson K, 1994, CLIN ORTHOP RELAT R, V302, P191
   DROST TF, 1989, J TRAUMA, V29, P1331, DOI 10.1097/00005373-198910000-00006
   FISCHER MD, 1991, J BONE JOINT SURG AM, V73A, P1316, DOI 10.2106/00004623-199173090-00005
   FRANCEL TJ, 1992, PLAST RECONSTR SURG, V89, P478, DOI 10.1097/00006534-199203000-00014
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   GORMAN PW, 1989, CLIN ORTHOP RELAT R, V243, P58
   Grimard G, 1996, CLIN ORTHOP RELAT R, P62
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Gustilo RB, 1969, CLIN ORTHOP RELAT R, V66, P150
   Hallock GG, 2000, J TRAUMA, V48, P913, DOI 10.1097/00005373-200005000-00016
   Hallock GG, 1996, ANN PLAS SURG, V36, P139, DOI 10.1097/00000637-199602000-00006
   Hammert W C, 2000, Am J Orthop (Belle Mead NJ), V29, P22
   Heinz TR, 1999, PLAST RECONSTR SURG, V104, P89, DOI 10.1097/00006534-199907000-00013
   Heller L, 2001, PLAST RECONSTR SURG, V108, P1029, DOI 10.1097/00006534-200109150-00036
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Jeng SF, 1997, PLAST RECONSTR SURG, V99, P744, DOI 10.1097/00006534-199703000-00022
   Khatod M, 2003, J TRAUMA, V55, P949, DOI 10.1097/01.TA.0000092685.80435.63
   KHOURI RK, 1992, CLIN PLAST SURG, V19, P773
   KHOURI RK, 1989, J TRAUMA, V29, P1086, DOI 10.1097/00005373-198908000-00005
   Maffi TR, 2001, J RECONSTR MICROSURG, V17, P431, DOI 10.1055/s-2001-16357
   McCrory AL, 2002, LARYNGOSCOPE, V112, P2161, DOI 10.1097/00005537-200212000-00006
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Muramatsu K, 2001, MICROSURG, V21, P362, DOI 10.1002/micr.21807
   PATZAKIS MJ, 1983, CLIN ORTHOP RELAT R, V178, P31
   Peterson SL, 2003, PLAST RECONSTR SURG, V112, P1371, DOI 10.1097/01.PRS.0000082815.79881.51
   Raveendran SS, 2004, BRIT J PLAST SURG, V57, P266, DOI 10.1016/j.bjps.2003.12.005
   SUOMINEN S, 1995, MICROSURG, V16, P396, DOI 10.1002/micr.1920160609
   WOOD MB, 1985, CLIN ORTHOP RELAT R, V201, P151
   Yajima H, 2002, MICROSURG, V22, P114, DOI 10.1002/micr.21735
   YAREMCHUK MJ, 1996, ACTA ORTHOP BELG, V62, P189
NR 42
TC 238
Z9 290
U1 0
U2 16
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD APR 1
PY 2006
VL 117
IS 4
BP 1315
EP 1322
DI 10.1097/01.prs.0000204959.18136.36
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 031IK
UT WOS:000236697800038
PM 16582806
DA 2026-07-24
ER

PT J
AU Clark, JM
   Rychlik, S
   Harris, J
   Seikaly, H
   Biron, VL
   O'Connell, DA
AF Clark, Jessica M.
   Rychlik, Shannon
   Harris, Jeffrey
   Seikaly, Hadi
   Biron, Vincent L.
   O'Connell, Daniel A.
TI Donor site morbidity following radial forearm free flap reconstruction
   with split thickness skin grafts using negative pressure wound therapy
SO JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
LA English
DT Article
DE Radial forearm free flap; Split thickness skin graft; Negative pressure
   wound therapy; Wrist; Hand; Patient-reported outcomes
ID OUTCOMES
AB BackgroundDonor site complications secondary to radial forearm free flap (RFFF) reconstruction can limit recovery. Optimizing hand and wrist function in the post-operative period may allow more efficient self-care and return to activities of daily living. Negative pressure wound dressings (NPD) may increase blood flow and perfusion as compared to static pressure dressings (SPD) designed to minimize shear forces during the healing period. This study aims to compare subjective and objective hand and wrist functional outcomes following RFFF reconstruction with split thickness skin grafts (STSG) in patients treated with NPD and SPD.MethodsAdult patients undergoing RFFF with STSG were identified preoperatively and randomized to receive NPD or SPD following their RFFF reconstruction. NPD involved a single-use, portable device capable of applying 80mmHg of negative pressure to the forearm donor site. SPD involved a volar splint. Dressings were left in place for seven days with subjective and objective function assessed at seven days, one month and three months postoperatively. The primary outcome was self-reported hand function as measured with the function subscale of the Michigan Hand Questionnaire (MHQ). Secondary outcomes included hand and wrist strength, range of motion, sensation, scar aesthetics, and skin graft complications.ResultsTwenty-four patients undergoing RFFF were randomized to NPD or SPD. Patients treated with NPD had improved MHQ self-reported functional scores as compared to those treated with SPD at seven days postoperatively (P=0.016). Flexion at seven days was improved in NPD group (P=0.031); however, all other strength and range of motion outcomes were similar between groups. There were no differences in rates of graft complications, scar aesthetics, or sensation.ConclusionsIn the immediate post-operative period, NPD was associated with improved patient-reported hand and wrist function. Wound care to optimize hand and wrist function could allow for improved patient outcomes in the immediate postoperative period.
C1 [Clark, Jessica M.; Rychlik, Shannon; Harris, Jeffrey; Seikaly, Hadi; Biron, Vincent L.; O'Connell, Daniel A.] Univ Alberta, Div Otolaryngol Head & Neck Surg, Dept Surg, 8440-112 St,1E4 Walter Mackenzie Ctr, Edmonton, AB T6G 2B7, Canada.
   [Harris, Jeffrey; Seikaly, Hadi; Biron, Vincent L.; O'Connell, Daniel A.] Alberta Head & Neck Ctr Oncol & Reconstruct, Edmonton, AB, Canada.
C3 University of Alberta
RP O'Connell, DA (通讯作者)，Univ Alberta, Div Otolaryngol Head & Neck Surg, Dept Surg, 8440-112 St,1E4 Walter Mackenzie Ctr, Edmonton, AB T6G 2B7, Canada.; O'Connell, DA (通讯作者)，Alberta Head & Neck Ctr Oncol & Reconstruct, Edmonton, AB, Canada.
EM jmclark@ualberta.ca; danielo@ualberta.ca
CR Andrews BT, 2006, LARYNGOSCOPE, V116, P1918, DOI 10.1097/01.mlg.0000235935.07261.98
   Avery CME, 2010, BRIT J ORAL MAX SURG, V48, P245, DOI 10.1016/j.bjoms.2009.09.004
   BARDSLEY AF, 1990, PLAST RECONSTR SURG, V86, P287, DOI 10.1097/00006534-199008000-00014
   Chau J, 2009, J OTOLARYNGOL-HEAD N, V38, P294, DOI 10.2310/7070.2009.070093
   Chio EG, 2010, OTOLARYNG HEAD NECK, V142, P174, DOI 10.1016/j.otohns.2009.11.003
   Chung KC, 1999, ANN PLAS SURG, V42, P619, DOI 10.1097/00000637-199906000-00006
   de Leon JM, 2009, ADV SKIN WOUND CARE, V22, P122, DOI 10.1097/01.ASW.0000305452.79434.d9
   Dziegielewski PT, 2010, ORAL ONCOL, V46, P612, DOI 10.1016/j.oraloncology.2010.05.006
   Harris BN, 2016, CURR OPIN OTOLARYNGO, V24, P447, DOI 10.1097/MOO.0000000000000286
   Hurd T, 2014, OSTOMY WOUND MANAG, V60, P30
   Jaquet Y, 2012, ARCH OTOLARYNGOL, V138, P38, DOI 10.1001/archoto.2011.216
   Knott PD, 2016, HEAD NECK-J SCI SPEC, V38, pE945, DOI 10.1002/hed.24131
   London DA, 2014, PLAST RECONSTR SURG, V133, P616, DOI 10.1097/PRS.0000000000000034
   O'Connell DA, 2008, ARCH OTOLARYNGOL, V134, P85, DOI 10.1001/archotol.134.1.85
   Pereira MP, 2015, CURR OPIN ANESTHESIO, V28, P546, DOI 10.1097/ACO.0000000000000226
   Richardson D, 1997, PLAST RECONSTR SURG, V99, P109, DOI 10.1097/00006534-199701000-00017
   Riecke B, 2015, INT J ORAL MAX SURG, V44, P937, DOI 10.1016/j.ijom.2015.02.021
   Upton D, 2013, J WOUND CARE, V22, P34, DOI 10.12968/jowc.2013.22.1.34
   van de Kar AL, 2005, PLAST RECONSTR SURG, V116, P514, DOI 10.1097/01.prs.0000172982.43599.d6
   Vidrine DM, 2005, OTOLARYNG HEAD NECK, V133, P403, DOI 10.1016/j.otohns.2005.04.028
   Webster J, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub2
   Xia CY, 2014, MOL MED REP, V9, P1749, DOI 10.3892/mmr.2014.1997
NR 22
TC 32
Z9 34
U1 0
U2 12
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
EI 1916-0216
J9 J OTOLARYNGOL-HEAD N
JI J. Otolaryngol-Head Neck Surg.
PD MAY 21
PY 2019
VL 48
AR 21
DI 10.1186/s40463-019-0344-9
PG 6
WC Otorhinolaryngology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Otorhinolaryngology
GA HZ4ID
UT WOS:000468809800001
PM 31113481
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Lee, K
   Murphy, PB
   Ingves, MV
   Duncan, A
   DeRose, G
   Dubois, L
   Forbes, TL
   Power, A
AF Lee, Kevin
   Murphy, Patrick B.
   Ingves, Matthew V.
   Duncan, Audra
   DeRose, Guy
   Dubois, Luc
   Forbes, Thomas L.
   Power, Adam
TI Randomized clinical trial of negative pressure wound therapy for
   high-risk groin wounds in lower extremity revascularization
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Article; Proceedings Paper
CT 37th Annual Meeting of the Canadian-Society-for-Vascular-Surgery (CSVS)
CY SEP 25-26, 2015
CL Victoria, CANADA
SP Canadian Soc Vasc Surg
ID SURGICAL SITE INFECTIONS; VASCULAR-SURGERY; CLASSIFICATION; INCISIONS;
   NSQIP
AB Objective: The surgical site infection (SSI) rate in vascular surgery after groin incision for lower extremity revascularization can lead to significant morbidity and mortality. This trial was designed to study the effect of negative pressure wound therapy (NPWT) on SSI in closed groin wounds after lower extremity revascularization in patients at high risk for SSI.
   Methods: A single-center, randomized, controlled trial was performed at an academic tertiary medical center. Patients with previous femoral artery surgical exposure, body mass index of > 30 kg/m(2) or the presence of ischemic tissue loss were classified as a high-risk patient for SSI. All wounds were closed primarily and patients were randomized to either NPWT or standard dressing. The primary outcome of the trial was postoperative 30-day SSI in the groin wound. The secondary outcomes included 90-day SSI, hospital duration of stay, readmissions or reoperations for SSI, and mortality.
   Results: A total of 102 patients were randomized between August 2014 and December 2015. Patients were classified as at high risk owing to the presence of previous femoral artery cut down (29%), body mass index of > 30 kg/m(2) (39%) or presence of ischemic tissue loss (32%). Revascularization procedures performed included femoral to distal artery bypass (57%), femoral endarterectomy (18%), femoral to femoral artery crossover (17%), and other procedures (8%). The primary outcome of 30-day SSI was 11% in NPWT group versus 19% in standard dressing group (P =.24). There was a statistically significant shorter mean duration of hospital stay in the NPWT group (6.4 days) compared with the standard group (8.9 days; P = .01). There was no difference in readmission or reoperation for SSI or mortality between the two groups.
   Conclusions: This study demonstrated a nonsignificant lower rate of groin SSI in high-risk revascularization patients with NPWT compared with standard dressing. Owing to a lower than expected infection rate, the study was underpowered to detect a difference at the prespecified level. The NPWT group did show significantly shorter mean hospital duration of stay compared with the standard dressing group.
C1 [Lee, Kevin; Duncan, Audra; DeRose, Guy; Dubois, Luc; Power, Adam] Western Univ, Dept Surg, Div Vasc Surg, London, ON, Canada.
   [Murphy, Patrick B.; Ingves, Matthew V.] Western Univ, Schulich Sch Med & Dent, Dept Surg, Div Gen Surg, London, ON, Canada.
   [Forbes, Thomas L.] Univ Toronto, Div Vasc Surg, Dept Surg, Toronto, ON, Canada.
C3 Western University (University of Western Ontario); Western University
   (University of Western Ontario); University of Toronto
RP Power, A (通讯作者)，Western Univ, Schulich Sch Med & Dent, Dept Vasc Surg, LHSC Victoria Campus 800,Commissioners Rd E, London, ON N6A 5W9, Canada.
EM adam.power@lhsc.on.ca
RI Murphy, Patrick/T-5337-2019
FU Resident Research Grant from Western University
FX Special thanks to Brenda Henry, Victoria Hospital, LHSC (London,
   Ontario, Canada), who provided tremendous help in this study as a wound
   specialist. The study was funded by a Resident Research Grant from
   Western University without any influence on study design, data
   collection, management or any input on publication. Kinetic Concepts Inc
   (San Antonio, Tex) donated all NPWT devices but had no influence on
   study design, data collection, management or any input on publication.
   KL and PM had full access to all the data in the study and takes
   responsibility for the integrity of the data and the accuracy of the
   data analysis.
CR Damrauer SM, 2010, J VASC SURG, V62
   Davenport DL, 2014, J VASC SURG, V60, P1266, DOI 10.1016/j.jvs.2014.05.051
   Dua A, 2014, J VASC SURG, V60, P1635, DOI 10.1016/j.jvs.2014.08.072
   Dumville JC, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003091.pub3
   Giles KA, 2010, ANN VASC SURG, V24, P48, DOI 10.1016/j.avsg.2009.05.003
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Greenblatt DY, 2008, YMVA, V54, P433
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Inui T, 2015, SEMIN VASC SURG, V28, P201, DOI 10.1053/j.semvascsurg.2016.02.002
   Ju MH, 2014, J AM COLL SURGEONS, V219, P371, DOI 10.1016/j.jamcollsurg.2014.04.009
   Kalish JA, 2014, J VASC SURG, V60, P1238, DOI 10.1016/j.jvs.2014.05.012
   Kuy S, 2014, ANN VASC SURG, V28, P53, DOI 10.1016/j.avsg.2013.08.002
   Lawlor DK, 2011, VASC ENDOVASC SURG, V45, P241, DOI 10.1177/1538574411399157
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   Murphy P, 2015, TRIALS, V16, DOI 10.1186/s13063-015-1026-1
   Ortega G, 2012, J SURG RES, V174, P33, DOI 10.1016/j.jss.2011.05.056
   Ott E, 2013, EPIDEMIOL INFECT, V141, P1207, DOI 10.1017/S095026881200180X
   Ozaki CK, 2015, J VASC SURG, V61, P419, DOI 10.1016/j.jvs.2014.07.034
   Pearson A, 2009, J HOSP INFECT, V73, P296, DOI 10.1016/j.jhin.2009.08.016
   SZILAGYI DE, 1972, ANN SURG, V176, P321, DOI 10.1097/00000658-197209000-00008
   Vogel TR, 2006, YMVA, V51, P122
   Wiseman JT, 2012, J VASC SURG, V62
   Zhang JQ, 2014, J VASC SURG, V59, P1331, DOI 10.1016/j.jvs.2013.12.032
NR 23
TC 84
Z9 92
U1 0
U2 7
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
J9 J VASC SURG
JI J. Vasc. Surg.
PD DEC
PY 2017
VL 66
IS 6
BP 1814
EP 1819
DI 10.1016/j.jvs.2017.06.084
PG 6
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery; Cardiovascular System & Cardiology
GA FN3UA
UT WOS:000415925300025
PM 28865981
DA 2026-07-24
ER

PT J
AU Yuan, S
   Zhang, TJ
   Zhang, D
   He, Q
   Du, MT
   Zeng, FW
AF Yuan, Song
   Zhang, Tingjiu
   Zhang, Dong
   He, Qin
   Du, Meiting
   Zeng, Fanwei
TI 被撤回的出版物: Impact of negative pressure wound treatment on incidence of
   surgical site infection in varied orthopedic surgeries: A systematic
   review and meta-analysis (Retracted article. See vol. 22, 2025)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Review; Retracted Publication
DE meta-analysis; negative pressure wound therapy; orthopaedic surgery;
   surgical site infection; total complications
ID KNEE ARTHROPLASTY; FRACTURE SURGERY; PRIMARY HIP; LOWER-LIMB; THERAPY;
   DRESSINGS; COMPLICATIONS
AB Negative pressure wound therapy (NPWT) is a popular treatment to heal infected wounds. This meta-analysis aimed to determine if NPWT was more effective than conventional wound dressings for surgical site infections (SSI) in varied orthopaedic surgeries. Literature was retrieved from seven electronic databases (Medline, Web of Science, PubMed, Embase, Google Scholar, Cochrane Library, and CNKI). Randomised control trials (RCT) and retrospective cohort studies (RS) involving arthroplasty, fracture, and spinal surgery were extracted. SSI was our primary outcome, while total complications and length of hospital stay were secondary outcomes. We carried out the risk of bias assessment and meta-analysis using the Cochrane Risk of Bias 2.0 tool and Stata 17.0. Among the 798 studies retrieved, 18 of them met our inclusion criteria. We identified 13 RCTs and 5 RSs. The results of meta-analysis showed that the incidence of SSI in the NPWT group was significantly lower relative to the control group (OR = 0.60, 95% CI 0.47 to 0.77, P < 0.001). Subgroup analyses revealed that the incidences of SSI involving arthroplasty, fracture, and spinal surgery in the NPWT group accounted for 46%, 69%, and 37% relative to the control group, respectively. The incidence of SSI in RS (OR = 0.27, 95% CI 0.13 to 0.56) was significantly lower than that in RCT (OR = 0.69, 95% CI 0.54 to 0.90) (P = 0.02). Moreover, patients in the NPWT group had a lower total complication rate (OR = 0.51, 95% CI 0.34 to 0.76) and shorter hospital stays (SMD = -0.42, 95% CI -0.83 to -0.02), although high heterogeneity existed. NPWT may be an efficient alternative to help prevent the incidence of SSI and total complications as well as achieved shorten hospital stay in varied orthopaedic surgeries. The rational use of NPWT should be based on the presence of patients' clinical conditions and relevant risk factors.
C1 [Yuan, Song; Zhang, Tingjiu; Zhang, Dong; He, Qin; Du, Meiting] Dazhou Cent Hosp, Dept Orthopaed, Dazhou, Peoples R China.
   [Zeng, Fanwei] Sichuan Prov Orthoped Hosp, Dept Spine, Chengdu, Peoples R China.
   [Zeng, Fanwei] Sichuan Prov Orthoped Hosp, Dept Spine, 132 West Sect 1,1st Ring Rd, Chengdu, Peoples R China.
   [He, Qin] Dazhou Cent Hosp, Dept Orthopaed, 151 Dadong St, Dazhou 635000, Sichuan, Peoples R China.
RP Zeng, FW (通讯作者)，Sichuan Prov Orthoped Hosp, Dept Spine, 132 West Sect 1,1st Ring Rd, Chengdu, Peoples R China.; He, Q (通讯作者)，Dazhou Cent Hosp, Dept Orthopaed, 151 Dadong St, Dazhou 635000, Sichuan, Peoples R China.
EM 569430200@qq.com; zaihude20101109@163.com
FU Dazhou Science Plan Project [17YYJC0004]
FX Dazhou Science Plan Project,Grant/Award Number: 17YYJC0004
CR Alverdy JC, 2020, LANCET INFECT DIS, V20, pE38, DOI 10.1016/S1473-3099(19)30756-X
   Colli A, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-160
   Cooper HJ, 2018, INJURY, V49, P386, DOI 10.1016/j.injury.2017.11.010
   Cooper HJ, 2016, J ARTHROPLASTY, V31, P1047, DOI 10.1016/j.arth.2015.11.010
   Cooper HJ, 2022, J ARTHROPLASTY, V37, pS790, DOI 10.1016/j.arth.2022.03.022
   Costa ML, 2020, JAMA-J AM MED ASSOC, V323, P519, DOI 10.1001/jama.2020.0059
   Costa ML, 2018, JAMA-J AM MED ASSOC, V319, P2280, DOI 10.1001/jama.2018.6452
   Crist BD, 2017, INJURY, V48, P1518, DOI 10.1016/j.injury.2017.04.055
   Dingemans SA, 2018, INT ORTHOP, V42, P747, DOI 10.1007/s00264-018-3781-6
   Gao JR, 2021, J ADV NURS, V77, P3980, DOI 10.1111/jan.14876
   Gillespie BM, 2015, SURG INNOV, V22, P488, DOI 10.1177/1553350615573583
   Grant-Freemantle MC, 2020, J ORTHOP TRAUMA, V34, P223, DOI 10.1097/BOT.0000000000001750
   Guyatt GH, 2008, BMJ-BRIT MED J, V336, P924, DOI 10.1136/bmj.39489.470347.AD
   Higuera-Rueda CA, 2021, J ARTHROPLASTY, V36, pS295, DOI 10.1016/j.arth.2021.02.076
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Hudson DA, 2015, INT WOUND J, V12, P195, DOI 10.1111/iwj.12080
   Iheozor-Ejiofor Zipporah, 2018, Cochrane Database Syst Rev, V7, pCD012522, DOI 10.1002/14651858.CD012522.pub2
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Keeney JA, 2019, J ARTHROPLASTY, V34, P723, DOI 10.1016/j.arth.2018.12.008
   Kuo FC, 2021, J ARTHROPLASTY, V36, P2612, DOI 10.1016/j.arth.2021.02.047
   Liu X, 2018, INT J SURG, V53, P72, DOI 10.1016/j.ijsu.2018.02.064
   Manoharan V, 2016, J ARTHROPLASTY, V31, P2487, DOI 10.1016/j.arth.2016.04.016
   Masters J, 2021, BONE JOINT J, V103B, P755, DOI 10.1302/0301-620X.103B4.BJJ-2020-1603.R1
   Namgoong S, 2018, WOUND REPAIR REGEN, V26, pS3, DOI 10.1111/wrr.12576
   Naylor RM, 2020, WORLD NEUROSURG, V137, pE257, DOI 10.1016/j.wneu.2020.01.152
   Newman JM, 2019, J ARTHROPLASTY, V34, P554, DOI 10.1016/j.arth.2018.11.017
   Nolff MC, 2016, TIERAERZTL PRAX K H, V44, P26, DOI 10.15654/TPK-150957
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Patel VP, 2007, J BONE JOINT SURG AM, V89A, P33, DOI 10.2106/JBJS.F.00163
   Redfern RE, 2017, J ARTHROPLASTY, V32, P3333, DOI 10.1016/j.arth.2017.06.019
   Shao JS, 2018, INT J SURG, V56, P124, DOI 10.1016/j.ijsu.2018.06.018
   Stannard JP, 2012, INT WOUND J, V9, P32, DOI 10.1111/j.1742-481X.2012.01017.x
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Sterne J.A. C., 2019, BMJ-BRIT MED J, V366, pl4898, DOI [DOI 10.1136/BMJ.L4898, 10.1136/bmj.l4898]
   Suzuki T, 2014, J ORTHOP SURG-HONG K, V22, P30, DOI 10.1177/230949901402200109
   Wang C, 2019, J ORTHOP SURG RES, V14, DOI 10.1186/s13018-019-1488-z
   Wang JM, 2022, INT ORTHOP, V46, P2629, DOI 10.1007/s00264-022-05531-w
   Zhou JM, 2020, SPINE, V45, P208, DOI 10.1097/BRS.0000000000003218
NR 39
TC 9
Z9 10
U1 0
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD AUG
PY 2023
VL 20
IS 6
BP 2334
EP 2345
DI 10.1111/iwj.14043
EA DEC 2022
PG 12
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA L4AN9
UT WOS:000898956100001
PM 36524330
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Robbins, JM
   Courtney, J
   Hingorani, A
AF Robbins, Justin M.
   Courtney, James
   Hingorani, Anil
TI Systematic review of groin incision surgical site infection preventative
   measures in vascular surgery
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Review
DE Surgical site infection; Groin; Inguinal; Prevention; Vascular surgery
ID PRESSURE WOUND THERAPY; PROPHYLACTIC MUSCLE FLAPS; METAANALYSIS;
   COMPLICATIONS; TRANSVERSE; PREVENTION; EXPERIENCE; IMPACT
AB Objective: Groin surgical site infections (SSIs) after open revascularization can lead to devastating consequences in patients. As a result, prevention has been crucial in minimizing the rate of SSIs. This review aims to evaluate the current body of literature regarding prevention,techniques including prophylactic flaps, incision technique, topical antibiotic use, closed-incision negative pressure wound therapy, and adhesive drapes.
   Methods: This review was conducted and reported in accordance with the PRISMA statement. A systematic review was conducted using the Google Scholar, PubMed, and Cochrane Review databases regarding the five prevention topics. The authors identified 1371 potential studies with 33 studies selected and analyzed after systematic review regarding the five preventative topics.
   Results: The primary outcome of interest was how the rate of SSI was affected with each preventative technique. As a result, the recommendations are as follows. We suggest prophylactic flaps be considered in high-risk surgical patients undergoing open arterial exposure of the groin (Grade 2C). We suggest consideration of transverse incisions for open arterial exposure of the groin as a means of SSI prevention (Grade 2C). Given the lack of data regarding topical antibiotics no recommendation can be made regarding its use, we suggest closed-incision negative pressure wound therapy be used in groin surgical incisions at high risk for SSI (Grade 2B). Given the paucity of data regarding adhesive drapes, such as Ioban, no recommendation can be made regarding its use.
   Conclusions: This review highlights the effects of various preventative techniques and their potential benefit in the prevention of SSI in the groin. However, there is a glaring deficit in the available data, emphasizing the need for additional robust studies to better delineate their effectiveness and implementation into surgical practice. The use of endovascular techniques continues to increase, thus limiting the number of open arterial procedures and the potential for further studies to be conducted. To provide the high-quality studies needed to better evaluate these prevention techniques, large multi-institutional collaboration will likely be necessary to provide the appropriate number of patients to evaluate true effectiveness.
C1 [Robbins, Justin M.] Wright State Univ, Dept Gen Surg, Boonshoft Sch Med, Dayton, OH USA.
   [Courtney, James] Florida State Univ, Coll Med, Tallahassee, FL USA.
   [Hingorani, Anil] NUY Langone Brooklyn, Div Vasc Surg, Brooklyn, NY USA.
   [Robbins, Justin M.] Wright State Univ, Dept Surg, 128 E Apple St,Ste WB7000, Dayton, OH 45409 USA.
C3 University System of Ohio; Wright State University Dayton; State
   University System of Florida; Florida State University; University
   System of Ohio; Wright State University Dayton
RP Robbins, JM (通讯作者)，Wright State Univ, Dept Surg, 128 E Apple St,Ste WB7000, Dayton, OH 45409 USA.
EM jmrobbins94@gmail.com
OI Robbins, Justin/0000-0002-1643-2698
CR ALEXANDER JW, 1985, ARCH SURG-CHICAGO, V120, P1357
   Andercou O, 2018, MEDICINE, V97, DOI [10.1097/MD.0000000000011350, 10.1097/md.0000000000011350]
   Antoniou GA, 2019, J VASC SURG, V70, P6
   Beirne C, 2008, VASCULAR, V16, P207, DOI 10.2310/6670.2008.00036
   Bejko J, 2015, J CARDIOVASC TRANSL, V8, P431, DOI 10.1007/s12265-015-9653-1
   Benrashid E, 2020, J VASC SURG, V71, P896, DOI 10.1016/j.jvs.2019.05.066
   Bertges DJ, 2021, J Vasc Surg, V74, P1
   Brewer MB, 2015, AM SURGEON, V81, P1163
   Canteras M, 2020, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD013153.pub2
   CHESTER JF, 1992, ANN ROY COLL SURG, V74, P112
   Engelhardt M, 2018, INT WOUND J, V15, P327, DOI 10.1111/iwj.12848
   Fischer JP, 2012, J VASC SURG, V55, P1081, DOI 10.1016/j.jvs.2011.10.110
   Gombert A, 2020, VASCULAR, V28, P274, DOI 10.1177/1708538119890960
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Gwilym BL, 2021, EUR J VASC ENDOVASC, V61, P636, DOI 10.1016/j.ejvs.2020.11.053
   Hasselmann J, 2020, ANN SURG, V271, P48, DOI 10.1097/SLA.0000000000003364
   Higgins JPT, 2011, BMJ-BRIT MED J, V343, DOI 10.1136/bmj.d5928
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Meiler LJ, 2021, J VASC SURG, V74, P1668, DOI 10.1016/j.jvs.2021.04.058
   Mohammed S, 2013, J VASC SURG, V57, P1079, DOI 10.1016/j.jvs.2012.09.073
   Murad MH, 2011, J VASC SURG, V53, P1375, DOI 10.1016/j.jvs.2011.01.036
   Ng JJ, 2021, ANZ J SURG, V91, P822, DOI 10.1111/ans.16448
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Obeid T, 2017, ANN VASC SURG, V43, P226, DOI 10.1016/j.avsg.2017.01.003
   Page MJ, 2021, BMJ-BRIT MED J, V372, DOI 10.1136/bmj.n71
   Parikh PP, 2018, ANN VASC SURG, V47, P143, DOI 10.1016/j.avsg.2017.08.019
   PITT HA, 1980, ANN SURG, V192, P356, DOI 10.1097/00000658-198009000-00011
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Rasheed H, 2021, ANN VASC SURG, V72, P578, DOI 10.1016/j.avsg.2020.09.046
   Sexton F, 2020, INT J SURG, V76, P94, DOI 10.1016/j.ijsu.2020.02.037
   Shiroky J, 2020, SURGERY, V167, P1001, DOI 10.1016/j.surg.2020.01.018
   Singh DP, 2019, PLAST RECONSTR SURG, V143, p41S, DOI 10.1097/PRS.0000000000005312
   Slim K, 2003, ANZ J SURG, V73, P712, DOI 10.1046/j.1445-2197.2003.02748.x
   Sörelius K, 2019, IN VIVO, V33, P1, DOI 10.21873/invivo.11431
   Svensson-Björk R, 2019, BJS-BRIT J SURG, V106, P310, DOI 10.1002/bjs.11100
   Swinnen J, 2010, ANN VASC SURG, V24, P336, DOI 10.1016/j.avsg.2009.07.020
   Turtiainen J, 2010, SCAND J SURG, V99, P167, DOI 10.1177/145749691009900312
   Wallace AB, 2022, ANN VASC SURG, V78, P77, DOI 10.1016/j.avsg.2021.05.049
   Webster J, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006353.pub4
   Wee IJY, 2019, EUR J VASC ENDOVASC, V58, P446, DOI 10.1016/j.ejvs.2018.12.021
   Wells G., 2008, The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses
   Zwanenburg PR, 2020, ANN SURG, V272, P81, DOI 10.1097/SLA.0000000000003644
NR 43
TC 15
Z9 16
U1 0
U2 3
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
EI 1097-6809
J9 J VASC SURG
JI J. Vasc. Surg.
PD JUN
PY 2023
VL 77
IS 6
BP 1836
EP +
DI 10.1016/j.jvs.2023.01.209
EA MAY 2023
PG 18
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA J9XV9
UT WOS:001013092300001
PM 36804782
OA Bronze
DA 2026-07-24
ER

PT J
AU Onan, IS
   Yildiz, O
   Tüzün, B
   Timur, B
   Haydin, S
AF Onan, Ismihan Selen
   Yildiz, Okan
   Tuzun, Behzat
   Timur, Baris
   Haydin, Sertac
TI Vacuum-Assisted Closure for Mediastinitis in Pediatric Cardiac Surgery:
   A Single-Center Experience
SO ARTIFICIAL ORGANS
LA English
DT Article
DE Pediatric cardiac surgery; Mediastinitis; Treatment; Vacuum-assited
   closure; Congenital heart disease
ID NEGATIVE PRESSURES; THERAPY
AB Vacuum-assisted closure (VAC) has been widely used to treat mediastinitis after congenital cardiac surgery, which is associated with a high risk of morbidity and mortality. The aim in this study is to review our 14 cases of mediastinitis treated with VAC therapy after congenital cardiac surgery. We retrospectively reviewed the medical records of 14 congenital heart patients with mediastinitis from January 2012 to March 2017. Patients with fever, wound discharge, sternal dehiscence, a positive wound culture or abscess diagnosed with computed tomography are accepted as mediastinitis. A VAC was applied to all our patients without irrigation or dressing the wound because of sterility concerns. The vacuuming of the wound was either 50 mm Hg or 75 mm Hg according to the sternal intactness. We gradually decreased the pressures and changed the VAC systems once every three days, after wound healing was seen and a negative culture was obtained and VAC was terminated. There were 14 patients (8 male and 6 female) with mediastinitis and all of them were treated using VAC. The mean age of the patients was 6.96 months (ranging from 0.5-26 months). The mean weight was 5.16 kg (2.8-12 kg). Three patients needed extracorporeal membrane oxygenation after the surgery. Mean onset of mediastinitis was 25.3 days. The wound cultures showed methicillin resistant coagulase negative streptococcus and methicillin-sensitive staphylococcus aureus in most cases. Acinetobacter, serratia, pseudomonas, and klebsiella were the other bacterial species seen in cultures. Two patients had mediastinitis symptoms, but their cultures were negative. VAC systems were changed 3.85 times on average. Mean duration of hospital stay was 49.9 days (21-104 days). One patient needed a muscle flap to close the thoracic cavity after mediastinitis. Two patients did not survive. Mediastinitis is a serious postoperative condition in pediatric cardiac surgery patients. Classical wound dressing and irrigation methods are not suitable in mediastinitis for the pediatric age group. Therefore, VAC therapy can be an effective way to successfully treat the situation.
C1 [Onan, Ismihan Selen; Yildiz, Okan; Tuzun, Behzat; Timur, Baris; Haydin, Sertac] Istanbul SBU Mehmet Akif Ersoy Thorac & Cardiovas, Istanbul, Turkey.
C3 Mehmet Akif Ersoy Thoracic Cardiovascular Surgery Education Research
   Hospital
RP Onan, IS (通讯作者)，Istanbul Mehmet Akif Ersoy Gogus Kalp Damar Cerra, Kalp Damar Cerrahi Anabilim Dali, TR-34303 Istanbul, Turkey.
EM selenibis@hotmail.com
RI Timur, Barış/KLD-2135-2024; tüzün, behzat/JZE-4500-2024
OI Timur, Barış/0000-0003-4446-6374; 
CR Aydin S, 2017, TURK GOGUS KALP DAMA, V25, P174, DOI 10.5606/tgkdc.dergisi.2017.13820
   Costello JP, 2014, J WOUND CARE, V23, P31, DOI 10.12968/jowc.2014.23.1.31
   Durandy Y, 2010, WORLD J CARDIOL, V2, P391, DOI 10.4330/wjc.v2.i11.391
   Filippelli S, 2015, J CARDIAC SURG, V30, P190, DOI 10.1111/jocs.12463
   Fleck Tatjana, 2006, Interact Cardiovasc Thorac Surg, V5, P285, DOI 10.1510/icvts.2005.122424
   Fleck Tatjana, 2008, Interact Cardiovasc Thorac Surg, V7, P801, DOI 10.1510/icvts.2008.177527
   Fuchs U, 2005, ANN THORAC SURG, V79, P526, DOI 10.1016/j.athoracsur.2004.08.032
   Huddleston Charles B, 2004, Semin Thorac Cardiovasc Surg, V16, P108, DOI 10.1053/j.semtcvs.2004.01.011
   Kadohama T, 2008, ANN THORAC SURG, V85, P1094, DOI 10.1016/j.athoracsur.2007.09.004
   Mokhtari A, 2006, ANN THORAC SURG, V82, P1063, DOI 10.1016/j.athoracsur.2006.04.085
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Petzina R, 2007, J THORAC CARDIOV SUR, V133, P1154, DOI 10.1016/j.jtcvs.2007.01.011
   Tortoriello TA, 2003, ANN THORAC SURG, V76, P1655, DOI 10.1016/S0003-4975(03)01025-7
   Ugaki S, 2010, INTERACT CARDIOV TH, V11, P247, DOI 10.1510/icvts.2010.235903
NR 14
TC 10
Z9 12
U1 0
U2 6
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0160-564X
EI 1525-1594
J9 ARTIF ORGANS
JI Artif. Organs
PD FEB
PY 2019
VL 43
IS 2
SI SI
BP 119
EP 124
DI 10.1111/aor.13321
PG 6
WC Engineering, Biomedical; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Transplantation
GA HM0WI
UT WOS:000459167900003
PM 30281163
DA 2026-07-24
ER

PT J
AU Steiert, AE
   Gohritz, A
   Schreiber, TC
   Krettek, C
   Vogt, PM
AF Steiert, Andreas E.
   Gohritz, Andreas
   Schreiber, Thomas C.
   Krettek, Christian
   Vogt, Peter M.
TI Delayed flap coverage of open extremity fractures after previous
   vacuum-assisted closure (VAC®) therapy - worse or worth?
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article
DE Open fractures; Soft tissue damage; Microsurgery; Delayed; Flap
   reconstruction
ID OPEN TIBIAL FRACTURES; DAMAGE CONTROL; MULTIPLE INJURIES; WOUND CLOSURE;
   RECONSTRUCTION; MANAGEMENT; CLASSIFICATION; DEFECTS; SALVAGE; TRAUMA
AB Background: Controversy remains regarding timing in the management of complex traumatic lower extremity defects. Many authors recommend a definitive bony and soft tissue reconstruction within a critical period of 72 h, yet in many patients this may be impossible due to concomitant injuries or delayed referral. However, little data are available on the results of delayed flap reconstruction of complex traumatic extremity defects, especially using new technologies of wound coverage such as vacuum-assisted closure (VAC (R)) therapy which may reduce the disadvantages of conventional open wound therapy prior to a subsequent flap reconstruction.
   Methods: We retrospectively analysed the soft tissue reconstructions in 43 open extremity fractures during a 4-year period with special regard to complications, overall flap loss and wound infection.
   Results: A total of 29 mate and 13 female patients with 33 open fractures of the tower and 10 of the upper extremity were included. All patients had been referred from a trauma centre at a mean interval of 19 days (range 1-96 days) after the trauma event with temporary VAC (R) of their wounds after initial fracture fixation and initial debridement of necrotic tissue. Flap reconstruction was thus only possible later than 72 h and definitive wound closure was achieved at a mean time of 28 days (range 3-106 days). Overall, three pedicled flaps were lost and one of 38 microsurgical free flaps (2.6%) underwent necrosis, the cause of which was unrelated to treatment delay.
   Conclusions: According to this study, the flap reconstructions performed beyond the frequently quoted critical interval yielded similar results to those of immediate reconstruction within the first 3 days, as reported in the literature.
   This strategy is in accordance with the principles of 'Damage Control Orthopaedics (DCO)' and may reduce the importance of emergency reconstructions, especially in poly-traumatised patients. (C) 2008 Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons.
C1 [Steiert, Andreas E.; Gohritz, Andreas; Vogt, Peter M.] Hannover Med Sch, Dept Plast Hand & Reconstruct Surg, D-30623 Hannover, Germany.
   [Schreiber, Thomas C.; Krettek, Christian] Hannover Med Sch, Dept Trauma Surg, D-30623 Hannover, Germany.
C3 Hannover Medical School; Hannover Medical School
RP Steiert, AE (通讯作者)，Hannover Med Sch, Dept Plast Hand & Reconstruct Surg, Carl Neuberg Str 1, D-30623 Hannover, Germany.
EM steiert.andreas@mh-hannover.de
RI Vogt, Peter/AAL-1332-2020
OI Krettek, Christian/0000-0001-9807-0020
CR *AM COLL SURG COMM, 2004, ADV TRAUM LIV SUPP A
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   ARNEZ ZM, 1991, CLIN PLAST SURG, V18, P449
   BAKER SP, 1974, J TRAUMA, V14, P187, DOI 10.1097/00005373-197403000-00001
   CIERNY G, 1983, CLIN ORTHOP RELAT R, P54
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Fail PA, 1998, REPROD TOXICOL, V12, P1, DOI 10.1016/S0890-6238(97)00095-6
   Georgescu AV, 2003, MICROSURG, V23, P206, DOI 10.1002/micr.10128
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Gopal S, 2000, J BONE JOINT SURG BR, V82B, P959, DOI 10.1302/0301-620X.82B7.10482
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   Heller L, 2001, PLAST RECONSTR SURG, V108, P1029, DOI 10.1097/00006534-200109150-00036
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Hertel R, 1999, ARCH ORTHOP TRAUM SU, V119, P7, DOI 10.1007/s004020050346
   Hildebrand F, 2004, INJURY, V35, P678, DOI 10.1016/j.injury.2004.03.004
   HOWE HR, 1987, AM SURGEON, V53, P205
   IZMAILOV GA, 1998, KHIRURGIIA MOSK, V1, P46
   LANGE RH, 1985, J TRAUMA, V25, P203, DOI 10.1097/00005373-198503000-00006
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Ninkovic M, 1996, SCAND J PLAST RECONS, V30, P37, DOI 10.3109/02844319609072403
   Ninkovic M, 1999, PLAST RECONSTR SURG, V103, P903, DOI 10.1097/00006534-199903000-00020
   Pape HC, 2003, UNFALLCHIRURG, V106, P85, DOI 10.1007/s00113-003-0589-6
   Roberts Craig S, 2005, Instr Course Lect, V54, P447
   RUSSELL GG, 1990, J BONE JOINT SURG BR, V72, P125, DOI 10.1302/0301-620X.72B1.2298770
   Scalea TM, 2000, J TRAUMA, V48, P613, DOI 10.1097/00005373-200004000-00006
   Sinclair JS, 1997, INJURY, V28, P581, DOI 10.1016/S0020-1383(97)00093-4
   Steiert AE., 2004, ZENTRALBL CHIR, V129, P98, DOI 10.1055/s-2004-822658
   Tropet Y, 1999, BRIT J PLAST SURG, V52, P462, DOI 10.1054/bjps.1999.3166
   Webb Lawrence X, 2002, J Am Acad Orthop Surg, V10, P303
   YAREMCHUK MJ, 1987, PLAST RECONSTR SURG, V80, P1
   Yazar S, 2004, PLAST RECONSTR SURG, V114, P1457, DOI 10.1097/01.PRS.0000138811.88807.65
NR 31
TC 91
Z9 103
U1 2
U2 11
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD MAY
PY 2009
VL 62
IS 5
BP 675
EP 683
DI 10.1016/j.bjps.2007.09.041
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 447RQ
UT WOS:000266209900028
PM 18373969
DA 2026-07-24
ER

PT J
AU Zannis, J
   Angobaldo, J
   Marks, M
   DeFramzo, A
   David, L
   Molnar, J
   Argenta, L
AF Zannis, John
   Angobaldo, Jeff
   Marks, Malcolm
   DeFramzo, Anthony
   David, Lisa
   Molnar, Joseph
   Argenta, Louis
TI Comparison of Fasciotomy Wound Closures Using Traditional Dressing
   Changes and the Vacuum-Assisted Closure Device
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE fasciotomy; VAC; wet-to-dry dressings; primary closure
ID DELAYED PRIMARY CLOSURE; COMPARTMENT SYNDROME
AB Fasciotomy wounds can be a major contributor to length of stay for patients as well as a difficult reconstructive challenge. Once the compartment pressure has been relieved and stabilized, the wound should be closed as quickly and early as possible to avoid later complications. Skin grafting can lead to morbidity and scarring at both the donor and fasciotomy site. Primary closure results in a more functional and esthetic outcome with less morbidity for the patient, but can often be difficult to achieve secondary to edema, skin retraction, and skin edge necrosis. Our objective was to examine fasciotomy wound outcomes, including time to definitive closure, comparing traditional wet-to-dry dressings, and the vacuum-assisted closure (VAC) device.
   This retrospective chart review included a consecutive series of patients over a 10-year period. This series included 458 patients who underwent 804 fasciotomies. Of these fasciotomy wounds, 438 received exclusively VAC. dressings, 270 received only normal saline wet-to-dry dressings, and 96 were treated with a combination of both. Of the sample, 408 patients were treated with exclusively VAC therapy or wet-to-dry dressings and 50 patients were treated with a combination of both.
   In comparing all wounds, there was a statistically significant higher rate of primary closure using the VAC versus traditional wet-to-dry dressings (P < 0.05 for lower extremities and P < 0.03 for upper extremities). The time to primary closure of wounds was shorter in the VAC. group in comparison with the non-VAC group.
   This study has shown that the use of the VAC for fasciotomy wound closure results in a higher rate of primary closure versus traditional wet-to-dry dressings. In addition, the time to primary closure of wounds or time to skin grafting is shorter when the VAC was employed. The VAC used in the described settings decreases hospitalization time, allows for earlier. rehabilitation, and ultimately leads to increased patient satisfaction.
C1 [Zannis, John; Angobaldo, Jeff; Marks, Malcolm; DeFramzo, Anthony; David, Lisa; Molnar, Joseph; Argenta, Louis] Wake Forest Univ, Bowman Gray Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27106 USA.
C3 Wake Forest University; Wake Forest Baptist Medical Center
RP Argenta, L (通讯作者)，Wake Forest Univ, Bowman Gray Sch Med, Dept Plast & Reconstruct Surg, Med Ctr Blvd, Winston Salem, NC 27106 USA.
EM largenta@wfubmc.edu
RI Molnar, Joseph/AEK-5540-2022
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BOXER LK, 2003, INTERNET J PLAST SUR, V1, P2
   Callanan I, 1997, J HAND SURG-BRIT EUR, V22B, P264, DOI 10.1016/S0266-7681(97)80078-2
   Chiverton N, 2000, INJURY, V31, P21, DOI 10.1016/S0020-1383(99)00193-X
   COHN BT, 1986, ORTHOPEDICS, V9, P1243
   DeFranzo AJ, 1999, PLAST RECONSTR SURG, V104, P2145, DOI 10.1097/00006534-199912000-00031
   Fitzgerald AM, 2000, BRIT J PLAST SURG, V53, P690, DOI 10.1054/bjps.2000.3444
   Harrah J, 2000, AM J SURG, V180, P55, DOI 10.1016/S0002-9610(00)00409-8
   Hussmann J, 1997, BURNS, V23, P154, DOI 10.1016/S0305-4179(96)00090-3
   Mbubaegbu CE, 1996, INJURY, V27, P613, DOI 10.1016/S0020-1383(96)00111-8
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Narayanan K, 1996, INJURY, V27, P449, DOI 10.1016/0020-1383(96)00029-0
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   Taylor RC, 2003, J AM COLL SURGEONS, V197, P872, DOI 10.1016/S1072-7515(03)00646-X
   Van der Velde M, 2005, ANN PLAS SURG, V55, P660, DOI 10.1097/01.sap.0000187181.59748.19
   Velmahos GC, 1997, WORLD J SURG, V21, P247, DOI 10.1007/s002689900224
   Willsey DB, 1997, J CLIN ANESTH, V9, P428, DOI 10.1016/S0952-8180(97)00073-1
   Zorrilla P, 2005, J TRAUMA, V59, P1515, DOI 10.1097/01.ta.0000199242.24511.30
NR 18
TC 88
Z9 138
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0148-7043
EI 1536-3708
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD APR
PY 2009
VL 62
IS 4
BP 407
EP 409
DI 10.1097/SAP.0b013e3181881b29
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 423OA
UT WOS:000264504400016
PM 19325346
DA 2026-07-24
ER

PT J
AU Caniano, DA
   Ruth, B
   Teich, S
AF Caniano, DA
   Ruth, B
   Teich, S
TI Wound management with vacuum-assisted closure: experience in 51
   pediatric patients
SO JOURNAL OF PEDIATRIC SURGERY
LA English
DT Article; Proceedings Paper
CT 35th Annual Meeting of the American-Pediatric-Surgical-Association
CY MAY 27-30, 2004
CL Ponte Vedra, FL
SP Amer Pediatr Surg Assoc
DE complex wounds; wound care; negative pressure therapy; vacuum-assisted
   wound care
ID NECROTIZING FASCIITIS; CLINICAL-EXPERIENCE
AB Background/Purpose: Soft tissue loss from infectious, vascular, and traumatic disorders often results in poor healing, painful wound care, and the need for repeated operations. This retrospective study evaluates a single-institutional experience with negative pressure therapy (NPT), using the vacuum-assisted closure (VAC) device in a group of children with diverse soft tissue problems.
   Methods: The medical records of 51 patients treated with NPT from January 2000 to July 2003 were reviewed for demographics, diagnosis, duration of VAC therapy, wound closure, recurrent disease, and complications.
   Results: Patients were classified by diagnosis: group 1: pilonidal disease (n = 21, primary 6 and recurrent = 15); group 2: sacral and extremity ulcers (n = 9); group 3: traumatic soft tissue wounds (n 9); and group 4: extensive tissue loss (n = 12) from the abdominal wall (n = 7), perineum (n = 2), thigh (n = 2), and axilla (n = 1). Group 1 had an average age of 16 years (range, 10-20 years), 67% were obese, and had an average length of follow-up of 13 months (range, 8-36 months). VAC was placed in the operating room in 95% with subsequent outpatient care that included dressing change 3 times weekly. Healing occurred in all patients with primary disease at an average of 37 days. For patients with recurrent disease, 12 healed at an average of 48 days and 3 developed recurrent sinuses. Group 2 was treated with VAC as a bridge to skin grafting or flap closure. All children in group 3 achieved healing without skin grafting at an average of 10 days and with acceptable cosmesis. Negative pressure therapy in group 4 was the only wound treatment in 10 patients and adjunctive to operative closure in 2. Complications from VAC occurred in 5 patients: retained sponge in 2 and device malfunction in 3.
   Conclusions: Negative pressure therapy offers a safe, cost-effective alternative to traditional complex wound care in children. Its advantages are less frequent dressing changes, outpatient management, resumption of daily activities including return to school, and a high degree of patient tolerance. (C) 2005 Elsevier Inc. All rights reserved.
C1 Ohio State Univ, Coll Med & Publ Hlth, Dept Surg, Div Pediat Surg, Columbus, OH 43205 USA.
   Childrens Hosp, Columbus, OH 43205 USA.
C3 University System of Ohio; Ohio State University; University System of
   Ohio; Ohio State University; Nationwide Childrens Hospital
RP Caniano, DA (通讯作者)，Ohio State Univ, Coll Med & Publ Hlth, Dept Surg, Div Pediat Surg, Columbus, OH 43205 USA.
EM canianod@chi.osu.edu
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Barillo DJ, 2003, WOUNDS, V15, P4
   Garner GB, 2001, AM J SURG, V182, P630, DOI 10.1016/S0002-9610(01)00786-3
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   Kovacs LH, 2001, ANN PLAS SURG, V47, P680, DOI 10.1097/00000637-200112000-00022
   Krasner Diane L, 2002, Ostomy Wound Manage, V48, P38
   McGuinness JG, 2003, DIS COLON RECTUM, V46, P274, DOI 10.1007/s10350-004-6535-z
   MILLER PR, 2002, J TRAUMA, V53, P649
   Mooney JF, 2000, CLIN ORTHOP RELAT R, P26
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Philbeck T E Jr, 1999, Ostomy Wound Manage, V45, P41
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
   Trent JT, 2002, WOUNDS, V14, P284
   Wu SH, 2000, EUR J PLAST SURG, V23, P174, DOI 10.1007/s002380050243
NR 15
TC 92
Z9 111
U1 0
U2 10
PU W B SAUNDERS CO
PI PHILADELPHIA
PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA
   19106-3399 USA
SN 0022-3468
J9 J PEDIATR SURG
JI J. Pediatr. Surg.
PD JAN
PY 2005
VL 40
IS 1
BP 128
EP 132
DI 10.1016/j.jpedsurg.2004.09.016
PG 5
WC Pediatrics; Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics; Surgery
GA 896IE
UT WOS:000226927000032
PM 15868572
DA 2026-07-24
ER

PT J
AU Batacchi, S
   Matano, S
   Nella, A
   Zagli, G
   Bonizzoli, M
   Pasquini, A
   Anichini, V
   Tucci, V
   Manca, G
   Ban, K
   Valeri, A
   Peris, A
AF Batacchi, Stefano
   Matano, Stefania
   Nella, Alessandra
   Zagli, Giovanni
   Bonizzoli, Manuela
   Pasquini, Andrea
   Anichini, Valentina
   Tucci, Valentina
   Manca, Giuseppe
   Ban, Kevin
   Valeri, Andrea
   Peris, Adriano
TI Vacuum-assisted closure device enhances recovery of critically ill
   patients following emergency surgical procedures
SO CRITICAL CARE
LA English
DT Article
ID ABDOMINAL COMPARTMENT SYNDROME; INTRAABDOMINAL HYPERTENSION;
   INTERNATIONAL-CONFERENCE; FASCIAL CLOSURE; OPEN ABDOMEN; PRESSURE;
   MANAGEMENT; HEMORRHAGE; EXPERTS
AB Introduction Critically ill surgical patients frequently develop intra-abdominal hypertension (IAH) leading to abdominal compartment syndrome (ACS) with subsequent high mortality. We compared two temporary abdominal closure systems (Bogota bag and vacuum-assisted closure (VAC) device) in intra-abdominal pressure (IAP) control.
   Methods This prospective study with a historical control included 66 patients admitted to a medical and surgical intensive care unit (ICU) of a tertiary care referral center (Careggi Hospital, Florence, Italy) from January 2006 to April 2009. The control group included patients consecutively treated with the Bogota bag (Jan 2006-Oct 2007), whereas the prospective group was comprised of patients treated with a VAC. All patients underwent abdominal decompressive surgery. Groups were compared based upon their IAP, SOFA score, serial arterial lactates, the duration of having their abdomen open, the need for mechanical ventilation (MV) along with length of ICU and hospital stay and mortality. Data were collected from the time of abdominal decompression until the end of pressure monitoring.
   Results The Bogota and VAC groups were similar with regards to demography, admission diagnosis, severity of illness, and IAH grading. The VAC system was more effective in controlling IAP (P < 0.01) and normalizing serum lactates (P < 0.001) as compared to the Bogota bag during the first 24 hours after surgical decompression. There was no significant difference between the SOFA scores. When compared to the Bogota, the VAC group had a faster abdominal closure time (4.4 vs 6.6 days, P = 0.025), shorter duration of MV (7.1 vs 9.9 days, P = 0.039), decreased ICU length of stay (LOS) (13.3 vs 19.2 days, P = 0.024) and hospital LOS (28.5 vs 34.9 days; P = 0.019). Mortality rate did not differ significantly between the two groups.
   Conclusions Patients with abdominal compartment syndrome who were treated with VAC decompression had a faster abdominal closure rate and earlier discharge from the ICU as compared to similar patients treated with the Bogota bag.
C1 [Batacchi, Stefano; Matano, Stefania; Nella, Alessandra; Zagli, Giovanni; Bonizzoli, Manuela; Pasquini, Andrea; Anichini, Valentina; Tucci, Valentina; Peris, Adriano] Careggi Teaching Hosp, Emergency Dept, Anaesthesia & Intens Care Unit, I-50139 Florence, Italy.
   [Manca, Giuseppe; Valeri, Andrea] Careggi Teaching Hosp, Dept Gen Surg, I-50139 Florence, Italy.
   [Ban, Kevin] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Emergency Med, Boston, MA 02215 USA.
C3 University of Florence; Azienda Ospedaliero Universitaria Careggi;
   University of Florence; Azienda Ospedaliero Universitaria Careggi;
   Harvard University; Harvard Medical School; Harvard University Medical
   Affiliates; Beth Israel Deaconess Medical Center
RP Zagli, G (通讯作者)，Careggi Teaching Hosp, Emergency Dept, Anaesthesia & Intens Care Unit, Viale Morgagni 85, I-50139 Florence, Italy.
EM giovanni.zagli@unifi.it
FU institutional funds
FX The study was supported by institutional funds only.
CR Aspesi M, 2002, Minerva Anestesiol, V68, P138
   Balogh Z, 2003, J TRAUMA, V54, P848, DOI 10.1097/01.TA.0000070166.29649.F3
   Balogh Z, 2003, AM J SURG, V186, P602, DOI 10.1016/j.amjsurg.2003.09.002
   Biancofiore G, 2008, MINERVA ANESTESIOL, V74, P5
   BRADLEY SE, 1947, J CLIN INVEST, V26, P1010, DOI 10.1172/JCI101867
   Cheatham ML, 2007, INTENS CARE MED, V33, P951, DOI 10.1007/s00134-007-0592-4
   Cheatham ML, 2009, SCAND J TRAUMA RESUS, V17, DOI 10.1186/1757-7241-17-10
   De Keulenaer BL, 2009, INTENS CARE MED, V35, P969, DOI 10.1007/s00134-009-1445-0
   De Waele JJ, 2006, CRIT CARE, V10, DOI 10.1186/cc4870
   Friedlander MH, 1998, J TRAUMA, V45, P433, DOI 10.1097/00005373-199809000-00002
   Gargiulo NJ III, 1998, ARCH SURG-CHICAGO, V133, P1351, DOI 10.1001/archsurg.133.12.1351
   Hong JJ, 2002, BRIT J SURG, V89, P591, DOI 10.1046/j.1365-2168.2002.02072.x
   Kotzampassi K, 2000, SURG TODAY, V30, P987, DOI 10.1007/s005950070018
   MacLean AA, 2008, ACTA CHIR BELG, V108, P212, DOI 10.1080/00015458.2008.11680206
   Malbrain MLNG, 2008, MINERVA ANESTESIOL, V74, P657
   Malbrain MLNG, 2008, MINERVA ANESTESIOL, V74, P1
   Malbrain MLNG, 2006, INTENS CARE MED, V32, P1722, DOI 10.1007/s00134-006-0349-5
   Malbrain Manu L N G, 2004, Curr Opin Crit Care, V10, P132, DOI 10.1097/00075198-200404000-00010
   Malbrain MLNG, 2009, WORLD J SURG, V33, P1110, DOI 10.1007/s00268-009-0039-x
   Malbrain MLNG, 2004, INTENS CARE MED, V30, P822, DOI 10.1007/s00134-004-2169-9
   Meldrum DR, 1997, AM J SURG, V174, P667, DOI 10.1016/S0002-9610(97)00201-8
   Myers JA, 2002, AM SURGEON, V68, P1029
   Reilly P, 2003, J TRAUMA, V54, P859
   RICHARDS WO, 1983, ANN SURG, V197, P183, DOI 10.1097/00000658-198302000-00010
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   Sugrue M, 1999, ARCH SURG-CHICAGO, V134, P1082, DOI 10.1001/archsurg.134.10.1082
   Sugrue M, 2005, CURR OPIN CRIT CARE, V11, P333, DOI 10.1097/01.ccx.0000170505.53657.48
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
NR 28
TC 73
Z9 83
U1 0
U2 0
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1466-609X
EI 1364-8535
J9 CRIT CARE
JI Crit. Care
PY 2009
VL 13
IS 6
AR R194
DI 10.1186/cc8193
PG 8
WC Critical Care Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 556DF
UT WOS:000274567900023
PM 19961614
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Patterson, CW
   Stalder, MW
   Richardson, W
   Steele, T
   Wise, MW
   St Hilaire, H
AF Patterson, Charles W.
   Stalder, Mark W.
   Richardson, William
   Steele, Thomas
   Wise, M. Whitten
   St Hilaire, Hugo
TI Timing of Free Flaps for Traumatic Wounds of the Lower Extremity: Have
   Advances in Perioperative Care Changed the Treatment Algorithm?
SO JOURNAL OF RECONSTRUCTIVE MICROSURGERY
LA English
DT Article
DE lower extremity trauma; traumatic wound; free flap reconstruction
ID VACUUM-ASSISTED CLOSURE; OPEN TIBIAL FRACTURES; LOWER-LIMB INJURY;
   MICROSURGICAL RECONSTRUCTION; MANAGEMENT; COVERAGE; THERAPY
AB Background Despite the landmark study by Godina 30 years ago, opinions still vary within the literature about the management of complex traumatic wounds in the lower extremity. We present a large series of lower extremity reconstructions with vascularized free tissue and examine the perioperative factors that influenced the success of these cases. Methods We reviewed 88 patients with free flap reconstruction of traumatic lower extremity wounds over 8 years. Primary outcomes were flap infections, flap loss, total flap-specific complications, and total recipient site complications. Independent variables specific to perioperative care including time to flap coverage, injury classification, exposed or infected hardware, prior osteomyelitis, use of wound vacuum-assisted closure (VAC) therapy, and concurrent polytrauma were investigated to establish their influence on primary outcomes. Each independent variable was assessed using Chi-square or Fisher's exact test and was included in a logistic regression analysis to establish significance. Results Of the 88 patients, 8 had flap loss, 8 had flap infections, and a total of 23 had primary adverse outcomes. Timing of the reconstruction, VAC use, injury classification, prior hardware or wound status, or presence of polytrauma had no statistically significant impact on the primary outcomes. Injury classification/severity on total recipient site complications ( p = 0.051) and flap-specific complications ( p = 0.073) trended toward significance; however, subgroup analysis did not achieve significance. Logistic regression of any recipient site complication including all independent variables similarly showed no significance. Conclusion Although the original study by Godina suggests early coverage is critical to optimize outcomes, in the modern era of advanced wound care, our study adds to a growing body of evidence that supports the de-emphasis of the 72-hour reconstruction interval. Our current management is focused on more effectively coordinating efficient peritraumatic and perioperative care on an individualized basis in the often very complicated polytrauma patient.
C1 [Patterson, Charles W.; Stalder, Mark W.; Richardson, William; Steele, Thomas; Wise, M. Whitten; St Hilaire, Hugo] Louisiana State Univ, Div Plast & Reconstruct Surg, Sch Med, 1542 Tulane Ave,Room 758A, New Orleans, LA 70112 USA.
C3 Louisiana State University System; Tulane University
RP St Hilaire, H (通讯作者)，Louisiana State Univ, Div Plast & Reconstruct Surg, Sch Med, 1542 Tulane Ave,Room 758A, New Orleans, LA 70112 USA.
EM hsthil@lsuhsc.edu
RI ; Richardson, William/D-3569-2011
OI Patterson, Charles/0000-0001-9892-4436; 
CR Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   BYRD HS, 1981, PLAST RECONSTR SURG, V68, P73, DOI 10.1097/00006534-198107000-00015
   CHEN SHT, 1992, PLAST RECONSTR SURG, V89, P882, DOI 10.1097/00006534-199205000-00016
   Colen DL, 2018, J RECONSTR MICROSURG, V34, P563, DOI 10.1055/s-0037-1607348
   FRANCEL TJ, 1992, PLAST RECONSTR SURG, V89, P478, DOI 10.1097/00006534-199203000-00014
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Haykal S, 2018, J RECONSTR MICROSURG, V34, P277, DOI 10.1055/s-0037-1621724
   Hendrickson SA, 2018, INJURY, V49, P1922, DOI 10.1016/j.injury.2018.07.023
   Hertel R, 1999, ARCH ORTHOP TRAUM SU, V119, P7, DOI 10.1007/s004020050346
   Hill JB, 2013, MICROSURG, V33, P9, DOI 10.1002/micr.21994
   Hou ZY, 2011, J TRAUMA, V71, P1705, DOI 10.1097/TA.0b013e31822e2823
   Hwang KT, 2016, MICROSURG, V36, P453, DOI 10.1002/micr.22428
   Karanas YL, 2008, MICROSURG, V28, P632, DOI 10.1002/micr.20551
   Kumar AR, 2009, PLAST RECONSTR SURG, V123, P218, DOI 10.1097/PRS.0b013e3181904da9
   Liu DSH, 2012, INJURY, V43, P772, DOI 10.1016/j.injury.2011.09.003
   Morykwas MJ, 2006, PLAST RECONSTR SURG, V117, p121S, DOI 10.1097/01.prs.0000225450.12593.12
   Raju A, 2014, J RECONSTR MICROSURG, V30, P427, DOI 10.1055/s-0034-1371510
   Starnes-Roubaud MJ, 2015, PRS-GLOB OPEN, V3, DOI 10.1097/GOX.0000000000000399
   Steiert AE, 2009, J PLAST RECONSTR AES, V62, P675, DOI 10.1016/j.bjps.2007.09.041
   YAREMCHUK MJ, 1987, PLAST RECONSTR SURG, V80, P1
NR 21
TC 22
Z9 29
U1 0
U2 4
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 0743-684X
EI 1098-8947
J9 J RECONSTR MICROSURG
JI J. Reconstr. Microsurg.
PD OCT
PY 2019
VL 35
IS 8
BP 616
EP 621
DI 10.1055/s-0039-1688712
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA IX9UO
UT WOS:000486036100009
PM 31087307
DA 2026-07-24
ER

PT J
AU Helgeson, MD
   Potter, BK
   Evans, KN
   Shawen, SB
AF Helgeson, Melvin D.
   Potter, Benjamin K.
   Evans, Korboi N.
   Shawen, Scott B.
TI Bioartificial Dermal Substitute: A Preliminary Report on Its Use for the
   Management of Complex Combat-Related Soft Tissue Wounds
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE blast injury; dermal substitute; Integra; negative pressure dressing;
   split-thickness skin graft
ID VACUUM-ASSISTED CLOSURE; SECURING SKIN-GRAFTS; ARTIFICIAL SKIN;
   RECONSTRUCTIVE SURGERY; REGENERATION TEMPLATE; CLINICAL-TRIAL; BURN
   INJURY; INTEGRA; EXPERIENCE; DRESSINGS
AB Objective: To report our institutional experience with the use of a bioartificial dermal substitute (Integra) combined with subatmospheric pressure [vacuum-assisted Closure (VAC)] dressings followed by delayed split-thickness skin grafting for management of complex combat-related soft tissue wounds secondary to blast injuries.
   Design: Retrospective review of patients treated December 2004 through November 2005.
   Setting: Military treatment facility.
   Patients/Participants: Integra grafting was performed 18 times in 16 wounds at our institution. Indications for Integra placement were wounds not amenable to simple split-thickness skin grafting. specifically those with substantial exposed bone and/or tendon.
   Intervention: Patients underwent an average of 8.5 irrigation and debridement procedures and concurrent VAC dressings prior to placement of the Integra. Following Integra grafting. all patients were managed with VAC dressings, changed every 3 to 4 days at the bedside or in clinic, with subsequent split-thickness skin grafting an average of 19 days later.
   Main Outcome Measurements: The mechanism and date of injury, size of residual soft tissue deficit, indication for Integra placement, number of irrigation and debridement procedures prior to Integra placement, days from injury to Integra placement, days from Integra placement to split-thickness skin grafting, and clinical outcome were recorded.
   Results: Integra placement and Subsequent skin grafting was successful in achieving durable and cosmetic definitive coverage in 15 of 16 wounds with two of these patients requiring repeat Integra application. Two patients with difficult VAC dressing placement had early Integra graft failure but successfully healed following repeated Integra application and skin grafting.
   Conclusions: Bioartificial dermal substitute grafting, when coupled with subatmospheric dressing management and delayed split-thickness skin grafting, is an effective technique for managing complex combat-related soft tissue wounds with exposed tendon. This can potentially lessen the need for local rotational or free flap coverage.
C1 [Helgeson, Melvin D.; Potter, Benjamin K.; Evans, Korboi N.; Shawen, Scott B.] Walter Reed Army Med Ctr, Dept Orthopaed & Rehabil, Washington, DC 20307 USA.
C3 Walter Reed National Military Medical Center; United States Department
   of Defense; United States Army
RP Shawen, SB (通讯作者)，Walter Reed Army Med Ctr, Orthopaed Surg Serv, 6900 Georgia Ave NW,Bldg 2,Clin 5A, Washington, DC 20307 USA.
EM Scott.Shawen@na.amedd.army.mil
RI Potter,, Benjamin K/U-1769-2019
OI Potter,, Benjamin K/0000-0002-8771-0317
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Bansky R, 2005, Bratisl Lek Listy, V106, P221
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   BURKE JF, 1981, ANN SURG, V194, P413, DOI 10.1097/00000658-198110000-00005
   Dantzer E, 2001, BRIT J PLAST SURG, V54, P659, DOI 10.1054/bjps.2001.3684
   Dantzer E, 2003, BRIT J PLAST SURG, V56, P764, DOI 10.1016/S0007-1226(03)00366-7
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Demarest GB, 2003, WOUNDS, V15, P250
   Enoch S, 2005, J MED ETHICS, V31, P2, DOI 10.1136/jme.2003.005272
   Fang P, 2002, J BURN CARE REHABIL, V23, P327, DOI 10.1097/00004630-200209000-00005
   Fitton AR, 2001, BRIT J PLAST SURG, V54, P208, DOI 10.1054/bjps.2000.3525
   Frame JD, 2004, PLAST RECONSTR SURG, V113, P1330, DOI 10.1097/01.PRS.0000111883.93604.85
   Gottleib M E., 2004, J BURNS SURG WOUND C, V3, P4
   HEIMBACH D, 1988, ANN SURG, V208, P313, DOI 10.1097/00000658-198809000-00008
   Heimbach DM, 2003, J BURN CARE REHABIL, V24, P42, DOI 10.1097/00004630-200301000-00009
   Heitland A, 2004, BURNS, V30, P471, DOI 10.1016/j.burns.2004.01.010
   Jeschke MG, 2004, PLAST RECONSTR SURG, V113, P525, DOI 10.1097/01.PRS.0000100813.39746.5A
   Khouri RK, 1998, PLAST RECONSTR SURG, V102, P711, DOI 10.1097/00006534-199809030-00015
   Kramers-de Quervain IA, 2001, J BONE JOINT SURG AM, V83A, P239, DOI 10.2106/00004623-200102000-00012
   Machens HG, 2000, CELLS TISSUES ORGANS, V167, P88, DOI 10.1159/000016772
   McEwan W, 2004, BURNS, V30, P259, DOI 10.1016/j.burns.2003.11.011
   Moiemen NS, 2001, PLAST RECONSTR SURG, V108, P93, DOI 10.1097/00006534-200107000-00015
   Molnar JA, 2004, PLAST RECONSTR SURG, V113, P1339, DOI 10.1097/01.PRS.0000112746.67050.68
   Orgill DP, 1999, ANN NY ACAD SCI, V888, P233, DOI 10.1111/j.1749-6632.1999.tb07959.x
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   STERN R, 1990, Journal of Burn Care and Rehabilitation, V11, P7, DOI 10.1097/00004630-199001000-00003
   Suzuki S, 1999, ANN PLAS SURG, V43, P439, DOI 10.1097/00000637-199910000-00017
   Violas P, 2005, J PEDIATR ORTHOP B, V14, P381, DOI 10.1097/01202412-200509000-00013
   Wang JCY, 2000, BRIT J PLAST SURG, V53, P70, DOI 10.1054/bjps.1999.3201
   Webb Lawrence X, 2002, J Am Acad Orthop Surg, V10, P303
   Wolter TP, 2005, BRIT J PLAST SURG, V58, P416, DOI 10.1016/j.bjps.2004.04.008
   YANNAS IV, 1980, J BIOMED MATER RES, V14, P65, DOI 10.1002/jbm.820140108
   YANNAS IV, 1980, J BIOMED MATER RES, V14, P107, DOI 10.1002/jbm.820140203
   Young RC, 2004, BURNS, V30, P723, DOI 10.1016/j.burns.2004.03.017
NR 35
TC 92
Z9 115
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0890-5339
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD JUL
PY 2007
VL 21
IS 6
BP 394
EP 399
DI 10.1097/BOT.0b013e318070c028
PG 6
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 370SX
UT WOS:000260784500007
PM 17620998
DA 2026-07-24
ER

PT J
AU Shi, H
   Zhu, L
   Chen, L
   Jiang, ZL
   Xu, ZY
   Wu, XT
AF Shi, Hang
   Zhu, Lei
   Chen, Lu
   Jiang, Zan-Li
   Xu, Zheng-Yuan
   Wu, Xiao-Tao
TI A Novel Technique for Treating Early Deep Surgical Site Infection After
   Posterior Lumbar Fusion with Instrumentation
SO WORLD NEUROSURGERY
LA English
DT Article
DE -Stage incision suture; Closed suction irrigation system; Deep surgical
   site infection; Incisional vacuum-assisted closure; Posterior lumbar
   fusion with instrumentation
ID PRESSURE WOUND THERAPY; ERYTHROCYTE SEDIMENTATION-RATE; C-REACTIVE
   PROTEIN; SPINAL SURGERY; CONTINUOUS-IRRIGATION; COMPLICATIONS;
   DEHISCENCE; PREVENTION; PREDICTOR
AB -OBJECTIVE: To introduce a novel technique of using incisional vacuum-assisted closure (VAC) after 1-stage incision suture combined with closed suction irrigation system (CSIS) for treating early deep surgical site infection (SSI) after posterior lumbar fusion with instrumentation and to compare it with traditional CSIS. -METHODS: This was a retrospective study. Patients with early deep SSI after posterior lumbar fusion with instru-mentation from January 2013 to May 2020 who were treated by meticulous debridement followed by either CSIS or incisional VAC after 1-stage incision suture combined with CSIS were identified. The demographic characteristics, treatment features, and outcomes were analyzed and compared between the 2 treatment methods. -RESULTS: A total of 48 patients (48/5016, 0.96%) devel -oped early deep SSI, 46 of whom were enrolled in this study. This included 24 patients in the CSIS group (group 1) and 22 patients in the incisional VAC after 1-stage incision suture combined with CSIS group (group 2). All patients received follow-up, with an average of 19.7 months (range, 13e30 months). There were no significant differences in demographic characteristics in both groups (P > 0.05). The -umber of VAC foam dressing or ordinary dressing changes (P < 0.001), number of debridements (P = 0.028), intrave-nous antibiotic duration (P = 0.042), oral antibiotic dura-tion (P = 0.019), and hospital stay (P = 0.029) in group 1 were significantly higher than those in group 2. The irrigation duration in group 1 was significantly shorter than that in group 2 (P = 0.007). All patients were eventually cured with satisfactory outcomes. -CONCLUSIONS: Compared with CSIS, incisional VAC after 1-stage incision suture combined with CSIS may be recommended considering that it has fewer dressing changes, fewer debridements, longer irrigation duration, shorter duration of antibiotic use, shorter hospital stay, and more convenient nursing care.
C1 [Shi, Hang; Zhu, Lei; Chen, Lu; Jiang, Zan-Li; Xu, Zheng-Yuan; Wu, Xiao-Tao] Southeast Univ, Zhongda Hosp, Sch Med, Dept Spine Surg, Nanjing, Peoples R China.
C3 Southeast University - China
RP Wu, XT (通讯作者)，Southeast Univ, Zhongda Hosp, Sch Med, Dept Spine Surg, Nanjing, Peoples R China.
EM wuxiaotaospine@seu.edu.cn
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   Anderson PA, 2017, NEUROSURGERY, V80, pS114, DOI 10.1093/neuros/nyw066
   Aono H, 2007, J BONE JOINT SURG BR, V89B, P1478, DOI 10.1302/0301-620X.89B11.19478
   Blumberg TJ, 2018, SPINE J, V18, P300, DOI 10.1016/j.spinee.2017.07.173
   Chen SH, 2018, CLIN SPINE SURG, V31, P225, DOI 10.1097/BSD.0000000000000633
   Daldal I, 2020, ANN TRANSL MED, V8, DOI 10.21037/atm.2019.11.60
   Dyck BA, 2019, J NEUROSURG-SPINE, V31, P430, DOI 10.3171/2019.2.SPINE18947
   Fujita R, 2019, J ORTHOP SCI, V24, P963, DOI 10.1016/j.jos.2019.09.002
   Hoeller S, 2021, EUR SPINE J, V30, P1261, DOI 10.1007/s00586-021-06782-8
   Ishii M, 2013, GLOB SPINE J, V3, P95, DOI 10.1055/s-0033-1343072
   Jones GA, 2007, J NEUROSURG-SPINE, V6, P407, DOI 10.3171/spi.2007.6.5.407
   Kang BU, 2010, J NEUROSURG-SPINE, V13, P158, DOI 10.3171/2010.3.SPINE09403
   Kobayashi K, 2020, SPINE, V45, P1459, DOI 10.1097/BRS.0000000000003545
   Koutsoumbelis S, 2011, J BONE JOINT SURG AM, V93A, P1627, DOI 10.2106/JBJS.J.00039
   Lee R, 2018, EUR SPINE J, V27, P2536, DOI 10.1007/s00586-018-5612-2
   Lian XF, 2014, J SPINAL DISORD TECH, V27, pE315, DOI 10.1097/BSD.0000000000000122
   Liu JM, 2018, SPINE, V43, P732, DOI 10.1097/BRS.0000000000002419
   Meredith DS, 2012, INT ORTHOP, V36, P439, DOI 10.1007/s00264-011-1427-z
   Mok JM, 2008, SPINE, V33, P415, DOI 10.1097/BRS.0b013e318163f9ee
   Mueller KB, 2021, NEUROSURGERY, V88, pE445, DOI 10.1093/neuros/nyab040
   Naylor RM, 2020, WORLD NEUROSURG, V137, pE257, DOI 10.1016/j.wneu.2020.01.152
   Nie H, 2011, SPINAL CORD, V49, P715, DOI 10.1038/sc.2010.190
   Ogihara S, 2020, WORLD NEUROSURG, V134, pE524, DOI 10.1016/j.wneu.2019.10.117
   Ousey KJ, 2013, SPINE J, V13, P1393, DOI 10.1016/j.spinee.2013.06.040
   Pesenti S, 2018, EUR SPINE J, V27, P2469, DOI 10.1007/s00586-018-5733-7
   Radcliff KE, 2015, SPINE J, V15, P336, DOI 10.1016/j.spinee.2014.09.022
   Rohmiller MT, 2010, SPINE, V35, P642, DOI 10.1097/BRS.0b013e3181b616eb
   THELANDER U, 1992, SPINE, V17, P400, DOI 10.1097/00007632-199204000-00004
   Yuan W, 2018, SPINE, V43, pE1089, DOI 10.1097/BRS.0000000000002615
   Zeng JK, 2019, WORLD NEUROSURG, V127, pE389, DOI 10.1016/j.wneu.2019.03.130
   Zheng S, 2020, INT ORTHOP, V44, P2211, DOI 10.1007/s00264-020-04567-0
   Zhou JM, 2020, SPINE, V45, P208, DOI 10.1097/BRS.0000000000003218
NR 32
TC 4
Z9 5
U1 0
U2 6
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1878-8750
EI 1878-8769
J9 WORLD NEUROSURG
JI World Neurosurg.
PD DEC
PY 2021
VL 156
BP E167
EP E174
DI 10.1016/j.wneu.2021.09.016
EA NOV 2021
PG 8
WC Clinical Neurology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA XG8VJ
UT WOS:000725025500034
PM 34509677
DA 2026-07-24
ER

PT J
AU Dua, A
   Rothenberg, KA
   Lavingia, K
   Ho, VT
   Rao, C
   Desai, SS
AF Dua, Anahita
   Rothenberg, Kara A.
   Lavingia, Kedar
   Ho, Vy T.
   Rao, Christina
   Desai, Sapan S.
TI Outcomes of Gracilis Muscle Flaps in the Management of Groin
   Complications after Arterial Bypass with Prosthetic Graft
SO ANNALS OF VASCULAR SURGERY
LA English
DT Article; Proceedings Paper
CT 41st Annual Meeting of the Midwestern-Vascular-Surgical-Society
CY SEP 07-09, 2017
CL Chicago, IL
SP Midwestern Vasc Surg Soc
ID INFECTIONS; COVERAGE
AB Background: This study details 2-year outcomes of a modified gracilis muscle flap (GMF) technique in providing tissue coverage for groin complications after arterial bypass surgery with synthetic graft.
   Methods: All patients who developed groin infections after lower extremity arterial bypass with synthetic graft who underwent a GMF technique were included from June 2014 to March 2017 from a prospectively collected, purpose-built institutional database. Modifications to the standard technique included identification of the muscle using ultrasound to ensure precise skip incisions, preservation of the segmental blood supply, widening of the tunnel through which the muscle is retroflexed, placement of a wound vacuum-assisted closure for healing, and lifelong antibiotics. Demographics, laboratory values, bypass procedure, length of stay (LOS), disposition, and 1-, 3-, 6-, 12-, and 24-month follow-up data were collected. Analysis was performed via descriptive statistics.
   Results: Over the 3-year study period, 22 patients underwent GMF after complications resulted from arterial bypass surgery. Types of bypass included aortobifemoral (32%), axillobifemoral (14%), femoral-femoral (23%), femoral-popliteal or mixed distal (27%), and thigh graft for dialysis (4%). Forty-five percentage of patients presented with graft infection, 50% with wound dehiscence, and 5% with graft disruption and bleeding. Only 23% of patients were candidates for sartorius muscle flap at the time of their initial procedure. The average case length was 64 + 19 min. Sixty-four percentage of patients were discharged home with home health care and the remainder to a skilled nursing facility. The average LOS was 6.1 + 3.4 days. Fifty-four percentages of wounds were healed at 1 month and 100% at 3 months with adjunctive vacuum-assisted closure therapy and lifelong antibiotics. Sixty percentage of patients were still alive at 24 months, with 33% of grafts still patent at that time. Median survival was 18.1 months, and median graft patency was 17.9 months.
   Conclusions: GMF is a safe and effective treatment for groin complications after arterial bypass surgery with synthetic graft. Owing to its versatility, area of coverage, ease of use, and durability, it potentially should be considered as a primary form of muscle coverage for groin complications.
C1 [Dua, Anahita; Rothenberg, Kara A.; Lavingia, Kedar; Ho, Vy T.] Stanford Hlth Care, Dept Surg, Div Vasc Surg, Stanford, CA USA.
   [Rao, Christina; Desai, Sapan S.] Northwest Community Hosp, Dept Vasc Surg, Arlington Hts, IL 60005 USA.
C3 Stanford University; Stanford Medicine
RP Desai, SS (通讯作者)，Northwest Community Hosp, Dept Vasc Surg, Arlington Hts, IL 60005 USA.
EM sapan.desai@surgisphere.com
OI Rothenberg, Kara/0000-0002-5123-5876; Ho, Vy Thuy/0000-0002-5570-0536
CR Ali AT, 2016, J VASC SURG, V64, P452, DOI 10.1016/j.jvs.2016.03.010
   Calligaro K D, 1994, Ann Vasc Surg, V8, P31, DOI 10.1007/BF02133403
   CHANG N, 1982, PLAST RECONSTR SURG, V70, P1
   DEVIRGILIO C, 1995, ANN VASC SURG, V9, P459, DOI 10.1007/BF02143860
   Fischer J, 2002, J VASC SURG, V55, P1081
   Herrera FA, 2009, AM SURGEON, V75, P877
   KIKTA MJ, 1987, J VASC SURG, V5, P566, DOI 10.1067/mva.1987.avs0050566
   Kishk T., 2010, EGYPT J PLAST RECONS, V34, P153
   Ktenidis K, 2012, CURRENT MANAGEMENT V
   Morasch MD, 2004, J VASC SURG, V39, P1277, DOI 10.1016/j.jvs.2004.02.011
   Rossetto LA, 2010, EUR J PLAST SURG, V33, P203, DOI 10.1007/s00238-010-0418-4
   Siracuse JJ, 2013, J VASC SURG, V57, P700, DOI 10.1016/j.jvs.2012.09.049
   Walter WR, 2016, CIRCULATION, V134, P412
   Young MH, 2012, INFECT DIS CLIN N AM, V26, P41, DOI 10.1016/j.idc.2011.09.004
   Zetrenne E, 2007, YALE J BIOL MED, V80, P112
NR 15
TC 15
Z9 15
U1 0
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD AUG
PY 2018
VL 51
BP 113
EP 118
DI 10.1016/j.avsg.2018.02.009
PG 6
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery; Cardiovascular System & Cardiology
GA GN5UO
UT WOS:000439132600018
PM 29660388
DA 2026-07-24
ER

PT J
AU Song, DH
   Wu, LC
   Lohman, RF
   Gottlieb, LJ
   Franczyk, M
AF Song, DH
   Wu, LC
   Lohman, RF
   Gottlieb, LJ
   Franczyk, M
TI Vacuum assisted closure for the treatment of sternal wounds: The bridge
   between debridement and definitive closure
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article; Proceedings Paper
CT 70th Annual Meeting of the ASPS/PSEF/ASMS
CY NOV 03-07, 2001
CL ORLANDO, FLORIDA
SP ASPS, PSEF, ASMS
ID MUSCLE FLAPS; STERNOTOMY; MEDIASTINITIS; EXPERIENCE; MANAGEMENT
AB A method to refine the treatment of sternal wounds using Vacuum Assisted Closure (V.A.C.) therapy as the bridge between debridement and delayed definitive closure is described. A retrospective review of 35 consecutive patients with sternal wound complications over a 2-year period (March of 1999 to March of 2001) was performed. The treatment of sternal wounds with traditional twice-a-day dressing changes was compared with the treatment with the wound V.A.C. device. An analysis of the number of days between initial debridement aid closure, number of dressing changes, number and types, of flaps needed for reconstruction, and complications was performed. Eighteen patients were treated with traditional twice-a-day dressing changes and 17 patients were treated with V.A.C. therapy alone. The two groups were similar regarding age, sex, type of cardiac procedure, and tape of sternal wound. The V.A.C. therapy group had a trend toward a shorter interval between debridement and closure, with a mean of 6.2 days, whereas die dressing change group had mean of 8.5 days. The V.A.C. therapy group had a significantly lower number of dressing changes, with a mean of three, whereas the twice-a-day dressing change group had a mean of 17 (p < 0.05). Reconstruction required an average of 1.5 soft-tissue flaps per patient treated with traditional dressing changes versus 0.9 soft-tissue flaps per patient for those treated with V.A.C. therapy (p < 0.05). Before closure, there was one death among patients undergoing dressing changes and three in the V.A.C. therapy group, all of which were unrelated to the management of the sternal wound. Patients with sternal wounds who have benefited from V.A.C. therapy alone have a significant decrease in the number of dressing changes and number of soft-tissue flaps needed for closure. Finally, the V.A.C. therapy group had a trend toward a decreased number of days between debridement and closure.
C1 Univ Chicago Hosp, Plast & Reconstruct Surg Sect, Chicago, IL 60637 USA.
   Univ Chicago Hosp, Dept Phys Therapy, Chicago, IL 60637 USA.
C3 University of Chicago; University of Chicago Medical Center; University
   of Illinois System; University of Illinois System; University of
   Chicago; University of Chicago Medical Center
RP Song, DH (通讯作者)，Univ Chicago Hosp, Plast & Reconstruct Surg Sect, 5841 S Maryland Ave,MC 6035, Chicago, IL 60637 USA.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   d'Udekem Y, 1998, CARDIOVASC SURG, V6, P415, DOI 10.1016/S0967-2109(98)00019-2
   GOTTLIEB LJ, 1994, ARCH SURG-CHICAGO, V129, P489
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   MAJURE JA, 1986, ANN THORAC SURG, V42, P9, DOI 10.1016/S0003-4975(10)61825-5
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   NAHAI F, 1989, PLAST RECONSTR SURG, V84, P434, DOI 10.1097/00006534-198909000-00009
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   PAIROLERO PC, 1986, ANN THORAC SURG, V42, P1, DOI 10.1016/S0003-4975(10)61822-X
   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
NR 13
TC 120
Z9 136
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0032-1052
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JAN
PY 2003
VL 111
IS 1
BP 92
EP 97
DI 10.1097/01.PRS.0000037686.14278.6A
PG 6
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 631WY
UT WOS:000180191700014
PM 12496568
DA 2026-07-24
ER

PT J
AU Nasr, A
   Ein, SH
AF Nasr, Ahmed
   Ein, Sigmund H.
TI A pediatric surgeon's 35-year experience with pilonidal disease in a
   Canadian children's hospital
SO CANADIAN JOURNAL OF SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; WOUND MANAGEMENT; SINUS; EXCISION
AB Background: There is an ongoing debate regarding the optimal surgical management for pilonidal disease in the pediatric population. The purpose of this study was to evaluate a pediatric surgeon's experience at a Canadian children's hospital over 35 years.
   Methods: We performed a retrospective review of the charts of patients seen and treated from July 1969 to December 2003, inclusive. All patients were evaluated for age, sex, clinical diagnosis, infection, treatment, healing time, complications and results.
   Results: In all, 121 adolescents with pilonidal disease (64 boys, 57 girls) with a mean age of 15 (range 12-19) years were evaluated at the same children's hospital. The 107 (88%) patients with infection (46% acute) underwent surgery. At operation, all 107 pilonidal cysts were either excised and packed open, marsupialized or excised and closed primarily without drainage under general anesthesia; the operation performed was arbitrarily chosen. Vacuum-assisted closure was not used. All patients received antibiotics. The time for healing after the initial operation in the group whose cysts were excised and packed open was at least twice as long (75 d) as in the other 2 groups (p = 0.031). Disease recurred in 24 (22%) patients, 6 (25%) of whom experienced 2 recurrences. Among the 90 patients in the excised and packed open group, 20 (22%) experienced recurrences and 5 (25%) experienced 2 recurrences. Among the 13 patients in the marsupialized group, 3 (23%) experienced recurrences and 1 (33%) experienced 2 recurrences. Among the 4 patients in the excised and closed primarily without drainage group, 1 (25%) experienced a recurrence and none experienced 2 recurrences (p = 0.12). Each recurrence was smaller than the original. All wounds eventually healed. There were no other complications and no deaths. A multivariable logistic regression analysis revealed that the type of surgical approach was not predictive of recurrence after controlling for age and sex.
   Conclusion: Age, sex and surgical approach were not predictive of recurrence. From our experience, excision and packing open the wound produced a longer morbidity but offered the same results compared with marsupialization or excision and primary closure without drainage.
C1 [Nasr, Ahmed; Ein, Sigmund H.] Hosp Sick Children, Div Gen Surg, Toronto, ON M5G 1X8, Canada.
C3 University of Toronto; Hospital for Sick Children (SickKids)
RP Ein, SH (通讯作者)，Hosp Sick Children, Div Gen & Thorac Surg, Rm 1526,555 Univ Ave, Toronto, ON M5G 1X8, Canada.
CR Akca T, 2005, BRIT J SURG, V92, P1081, DOI 10.1002/bjs.5074
   ASHCRAFT KW, 2000, PEDIAT SURG
   Bascom J, 2002, ARCH SURG-CHICAGO, V137, P1146, DOI 10.1001/archsurg.137.10.1146
   Bütter A, 2006, J PEDIATR SURG, V41, P940, DOI 10.1016/j.jpedsurg.2006.01.061
   Caniano DA, 2005, J PEDIATR SURG, V40, P128, DOI 10.1016/j.jpedsurg.2004.09.016
   Ertan T, 2005, AM J SURG, V190, P388, DOI 10.1016/j.amjsurg.2004.08.068
   Fonkalsrud E, 2003, Principles of Pediatric Surgery
   GOLLADAY ES, 1990, SOUTH MED J, V83, P922, DOI 10.1097/00007611-199008000-00017
   Gray S W., 1972, Embryology for Surgeons, V1st
   Grosfeld JL, 2006, PEDIAT SURG
   KARYDAKIS GE, 1992, AUST NZ J SURG, V62, P385, DOI 10.1111/j.1445-2197.1992.tb07208.x
   Lee SL, 2008, J PEDIATR SURG, V43, P1124, DOI 10.1016/j.jpedsurg.2008.02.042
   MCCOMB JG, 2006, ATLAS NEUROSURGICAL, P715
   MOHHAMED HA, 2005, SURG-J R COLL SURG E, V3, P73
   Morden P, 2005, PEDIATR SURG INT, V21, P793, DOI 10.1007/s00383-005-1543-1
   MORTON HS, 1959, TXB SURG, P710
   ROWE SA, 2003, SURG DIRECTIVES, P435
   Serour F, 2002, PEDIATR SURG INT, V18, P159
   YUCESAN S, 1993, EUR J EPIDEMIOL, V9, P373, DOI 10.1007/BF00157393
NR 19
TC 44
Z9 52
U1 0
U2 2
PU CMA-CANADIAN MEDICAL ASSOC
PI OTTAWA
PA 1867 ALTA VISTA DR, OTTAWA, ONTARIO K1G 5W8, CANADA
SN 0008-428X
EI 1488-2310
J9 CAN J SURG
JI Can. J. Surg.
PD FEB
PY 2011
VL 54
IS 1
BP 39
EP 42
DI 10.1503/cjs.028509
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 711RU
UT WOS:000286609900010
PM 21251431
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Bapat, V
   El-Muttardi, N
   Young, C
   Venn, G
   Roxburgh, J
AF Bapat, Vinayak
   El-Muttardi, Naguib
   Young, Christopher
   Venn, Graham
   Roxburgh, James
TI Experience with vacuum-assisted closure of sternal wound infections
   following cardiac surgery and evaluation of chronic complications
   associated with its use
SO JOURNAL OF CARDIAC SURGERY
LA English
DT Article
ID MUSCLE FLAPS; POSTSTERNOTOMY MEDIASTINITIS; STERNOTOMY; IRRIGATION;
   THERAPY
AB Objectives: We report our experience in use of Vacuum-assisted closure therapy (VAC) in the treatment of poststernotomy wound infection with emphasis on recurrent wound-related problems after use of VAC and their treatment. Methods: Between July 2000 and June 2003, 2706 patients underwent various cardiac procedures via median sternotomy. Forty-nine patients with postoperative sternal wound infection (1.9%) were managed with VAC. Wounds were classified as either superficial sternal wound infection (28 patients) or deep sternal wound infection (21 patients). In the superficial sternal wound infection group, 23 patients had VAC as definitive treatment (GroupA), while five patients (Group B) had VAC followed by surgical closure. Similarly, in the deep sternal wound infection group, 12 patients had VAC as definitive treatment (Group C), while nine patients had VAC followed by surgical closure (Group D). Patients were discharged after satisfactory wound closure. Upon discharge patients were followed up at interval of three to six months. Recurrent sternal problems when identified were investigated and additional surgical procedures were carried out when necessary. Results: There were nine deaths, all due to unrelated causes except in one patient who died of right ventricular rupture (Group C). Nine patients in Group A had recurrent wound problems of which six had VAC system for > 21 days. Three patients underwent extensive debridement due to sternal osteomyelitis. All eight patients in Group B presented with chronic wound-related problems and underwent multiple debridements. Four patients had laparoscopic omental flaps. In contrast 14 patients (Group B and D) who were treated with shorter duration of VAC followed by either a flap or direct surgical closure, did not present with recurrent problems. Conclusion: VAC therapy is a safe and reliable option in the treatment of sternal wound infection. However, prolonged use of VAC system as a replacement for surgical closure of sternal wound appears to be associated with recurrent problems of the sternal wound. Strategy of use of VAC for a short duration followed by early surgical closure appears favorable.
C1 [Bapat, Vinayak; Young, Christopher; Venn, Graham; Roxburgh, James] St Thomas Hosp, Dept Cardiothorac Surg, London, England.
   [El-Muttardi, Naguib] St Thomas Hosp, Dept Plast Surg, London, England.
C3 Guy's & St Thomas' NHS Foundation Trust; Guy's & St Thomas' NHS
   Foundation Trust
RP Bapat, V (通讯作者)，123 Turney Rd, London, England.
EM vnbapat@yahoo.com
RI /AAA-2540-2020
CR Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
   ARGENTA LC, 1997, ANN PLAST SURG, V38, P63
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   Davydov Iu A, 1992, Khirurgiia (Mosk), P21
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   El Gamel A, 1998, ANN THORAC SURG, V65, P41, DOI 10.1016/S0003-4975(97)01063-1
   Fleck TM, 2002, ANN THORAC SURG, V74, P1596, DOI 10.1016/S0003-4975(02)03948-6
   Francel TJ, 2001, ANN THORAC SURG, V72, P1411, DOI 10.1016/S0003-4975(00)02008-7
   GARNER JS, 1988, AM J INFECT CONTROL, V16, P128, DOI 10.1016/0196-6553(88)90053-3
   Gummert JF, 2002, THORAC CARDIOV SURG, V50, P87, DOI 10.1055/s-2002-26691
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   Luckraz H, 2003, J THORAC CARDIOV SUR, V125, P301, DOI 10.1067/mtc.2003.74
   LUCKRAZ H, 1996, CURR OPIN SURG INFEC, V4, P1
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Rand RP, 1998, ANN THORAC SURG, V65, P1046, DOI 10.1016/S0003-4975(98)00087-3
   Reade CC, 2003, AM SURGEON, V69, P1072
   SHUMACKER HB, 1963, ARCH SURG-CHICAGO, V86, P384
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Tang ATM, 2000, EUR J CARDIO-THORAC, V17, P482, DOI 10.1016/S1010-7940(00)00349-3
   Yasuura K, 1998, ANN SURG, V227, P455, DOI 10.1097/00000658-199803000-00019
NR 24
TC 46
Z9 50
U1 0
U2 2
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 0886-0440
J9 J CARDIAC SURG
JI J. Card. Surg.
PD MAY-JUN
PY 2008
VL 23
IS 3
BP 227
EP 233
DI 10.1111/j.1540-8191.2008.00595.x
PG 7
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 300PX
UT WOS:000255838800009
PM 18435637
DA 2026-07-24
ER

PT J
AU Sachithanandan, A
   Nanjaiah, P
   Nightingale, P
   Wilson, IC
   Graham, TR
   Rooney, SJ
   Keogh, BE
   Pagano, D
AF Sachithanandan, Anand
   Nanjaiah, Prakash
   Nightingale, Peter
   Wilson, Ian C.
   Graham, Timothy R.
   Rooney, Stephen J.
   Keogh, Bruce E.
   Pagano, Domenico
TI Deep sternal wound infection requiring revision surgery: impact on
   mid-term survival following cardiac surgery
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article; Proceedings Paper
CT 21st Annual Meeting of the
   European-Association-for-Cardio-Thoracic-Surgery (EACTS)
CY SEP 16-19, 2007
CL Geneva, SWITZERLAND
SP European Assoc Cardio Thorac Surg (EACTS)
DE deep sternal infection; survival
ID VACUUM-ASSISTED CLOSURE; LONG-TERM SURVIVAL; BYPASS GRAFT-SURGERY;
   RISK-FACTORS; COMPLICATIONS; MEDIASTINITIS
AB Objective: To assess the impact of deep sternal wound infection on in-hospital mortality and mid-term survival following adult cardiac surgery. Methods: Prospectively collected data on 4586 consecutive patients who underwent a cardiac surgical procedure via a median sternotomy from 1st January 2001 to 31st December 2005 were analysed. Patients with a deep sternal wound infection (DSWI) were identified in accordance with the Centres for Disease Control and Prevention guidelines. Nineteen variables (patient-related, operative and postoperative) were analysed. Logistic regression analysis was used to calculate a propensity score for each patient. Late survival data were obtained from the UK Central Cardiac Audit Database. Mean follow-up of DSWI patients was 2.28 years. Results: DSWI requiring revision surgery developed in 1.65% (76/4586) patients. Stepwise multivariable logistic regression analysis identified age, diabetes, a smoking history and ventilation time as independent predictors of a DSWI. DSWI patients were more likely to develop renal failure, require reventitation and a tracheostomy postoperatively. Treatment included vacuum assisted closure therapy in 81.5% (62/76) patients and sternectomy with musculocutaneous flap reconstruction in 35.5% (27/76) patients. In-hospital mortality was 9.2% (7/76) in DSWI patients and 3.7% (167/4510) in non-DSWI patients (OR 1.300 (0.434-3.894) p = 0.639). Survival with Cox regression analysis with mean propensity score (co-variate) showed freedom from all-cause mortality in DSWI at 1, 2, 3 and 4 years was 91%, 89%, 84% and 79%, respectively compared with 95%, 93%, 90% and 86%, respectively for patients without DSWI ((p = 0.082) HR 1.59 95% CI (0.94-2.68)). Conclusion: DSWI is not an independent predictor of a higher in-hospital mortality or reduced mid-term survival following cardiac surgery in this population. (C) 2008 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
C1 [Sachithanandan, Anand; Nanjaiah, Prakash; Wilson, Ian C.; Graham, Timothy R.; Rooney, Stephen J.; Pagano, Domenico] Univ Birmingham, NHS Fdn Trust, Dept Cardiothorac Surg, Birmingham B15 2TH, W Midlands, England.
   [Nightingale, Peter] Univ Hosp Birmingham, NHS Fdn Trust, Wellcome Trust Clin Res Facil, Birmingham, W Midlands, England.
   [Keogh, Bruce E.] UCL, Natl Inst Clin Outcomes Res, London WC1E 6BT, England.
C3 Oxford University Hospitals NHS Foundation Trust; University of
   Birmingham; Oxford University Hospitals NHS Foundation Trust; University
   of Birmingham; University of London; University College London
RP Pagano, D (通讯作者)，Univ Birmingham, NHS Fdn Trust, Dept Cardiothorac Surg, Birmingham B15 2TH, W Midlands, England.
EM domenico.pagano@uhb.nhs.uk
CR Borger MA, 1998, ANN THORAC SURG, V65, P1050, DOI 10.1016/S0003-4975(98)00063-0
   Braxton JH, 2000, ANN THORAC SURG, V70, P2004, DOI 10.1016/S0003-4975(00)01814-2
   Brunet F, 1996, J THORAC CARDIOV SUR, V111, P1200
   De Feo M, 2001, ANN THORAC SURG, V71, P324, DOI 10.1016/S0003-4975(00)02137-8
   Furnary AP, 1999, ANN THORAC SURG, V67, P352, DOI 10.1016/S0003-4975(99)00014-4
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   LOOP FD, 1990, ANN THORAC SURG, V49, P179, DOI 10.1016/0003-4975(90)90136-T
   Lu JCY, 2003, EUR J CARDIO-THORAC, V23, P943, DOI 10.1016/S1010-7940(03)00137-4
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Olsen MA, 2002, J THORAC CARDIOV SUR, V124, P136, DOI 10.1067/mtc.2002.122306
   PAIROLERO PC, 1991, ANN SURG, V213, P583, DOI 10.1097/00000658-199106000-00008
   Ridderstolpe L, 2001, EUR J CARDIO-THORAC, V20, P1168, DOI 10.1016/S1010-7940(01)00991-5
   ROBICSEK F, 1977, J THORAC CARDIOV SUR, V73, P267
   Roques F, 1999, EUR J CARDIO-THORAC, V15, P816, DOI 10.1016/S1010-7940(99)00106-2
   Sjögren J, 2005, ANN THORAC SURG, V80, P1270, DOI 10.1016/j.athoracsur.2005.04.010
   Stahle E, 1997, EUR J CARDIO-THORAC, V11, P1146, DOI 10.1016/S1010-7940(97)01210-4
   Toumpoulis IK, 2005, CHEST, V127, P464, DOI 10.1378/chest.127.2.464
   Trick WE, 2000, J THORAC CARDIOV SUR, V119, P108, DOI 10.1016/S0022-5223(00)70224-8
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
NR 21
TC 39
Z9 43
U1 0
U2 2
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
EI 1873-734X
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD APR
PY 2008
VL 33
IS 4
BP 673
EP 677
DI 10.1016/j.ejcts.2008.01.002
PG 5
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 292KU
UT WOS:000255265700041
PM 18243720
OA Bronze
DA 2026-07-24
ER

PT J
AU Shikara, M
   Waghmarae, S
   Vakharia, KT
AF Shikara, Meryam
   Waghmarae, Suneet
   Vakharia, Kalpesh T.
TI Closure of a Large Scalp Defect Using External Tissue Expansion
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE DermaClose; external tissue expanders; scalp defects; scalp
   reconstruction; reconstructive surgery
AB The limited laxity of the scalp and hair-bearing nature makes it difficult to optimally repair. Primary closure is limited to small defects, while healing by secondary intention requires underlying periosteum. Furthermore, the use of free flaps and skin grafting can lead to unfavorable cosmetic outcomes. This report describes a patient with a large parietal scalp dermatofibrosarcoma protuberans. Multiple resections resulted in a large scalp defect with exposed calvarium. Integra was placed over the exposed calvarium after each debridement and Negative Pressure Wound Therapy (NPWT) was applied. After granulation tissue formed, 2 DermaClose continuous external tissue expansion systems were installed. Following the application and tightening of the external tissue expanders, the wound was reduced in size, facilitating primary closure of the opposing edges. This process allowed for a large area to be covered with hair-bearing scalp with good cosmetic results.
C1 [Shikara, Meryam; Vakharia, Kalpesh T.] Univ Maryland Med Syst, Dept Otorhinolaryngol Head & Neck Surg, Baltimore, MD USA.
   [Waghmarae, Suneet; Vakharia, Kalpesh T.] Univ Maryland, Sch Med, Baltimore, MD USA.
   [Shikara, Meryam] Dept Otorhinolaryngol Head & Neck Surg, 16 South Eutaw St,Suite 500, Baltimore, MD 21201 USA.
C3 University System of Maryland; University of Maryland Baltimore;
   University System of Maryland; University of Maryland Baltimore
RP Shikara, M (通讯作者)，Dept Otorhinolaryngol Head & Neck Surg, 16 South Eutaw St,Suite 500, Baltimore, MD 21201 USA.
EM mshikara@som.umaryland.edu; suneet.waghmarae@som.umaryland.edu;
   kvakharia@som.umaryland.edu
CR Bajoghli AA, 2010, J DRUGS DERMATOL, V9, P149
   Lasheen Ahmed E, 2009, J Plast Reconstr Aesthet Surg, V62, pe251, DOI 10.1016/j.bjps.2007.05.019
   MacKay BJ, 2020, ADV WOUND CARE, V9, P525, DOI 10.1089/wound.2019.1112
   Mangubat EA, 2013, FACIAL PLAST SURG CL, V21, P487, DOI 10.1016/j.fsc.2013.05.006
   O'Reilly AG, 2012, ARCH FACIAL PLAST S, V14, P419, DOI 10.1001/archfacial.2012.662
NR 5
TC 2
Z9 2
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD JAN-FEB
PY 2023
VL 34
IS 1
DI 10.1097/SCS.0000000000008911
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 7T2RZ
UT WOS:000911295400022
PM 35968971
DA 2026-07-24
ER

PT J
AU Regan, MD
   Freeman, CM
   Talathi, N
   Spiegel, DA
   Flynn, JM
   Baldwin, KD
AF Regan, Maia D.
   Freeman, Colby M.
   Talathi, Nakul
   Spiegel, David A.
   Flynn, John M.
   Baldwin, Keith D.
TI Sealing the Deal: Incisional Vacuum Assisted Closure Following
   Neuromuscular Posterior Spinal Fusion is Associated With a Lower Rate of
   Infection
SO JOURNAL OF PEDIATRIC ORTHOPAEDICS
LA English
DT Article
DE spine; neuromuscular; infections; scoliosis
ID PRESSURE WOUND THERAPY; SCOLIOSIS SURGERY; RISK-FACTORS
AB Background: Surgical site infection (SSI) after posterior spinal fusion (PSF) to correct neuromuscular scoliosis is a devastating complication in pediatric patients. Incisional Vacuum-Assisted Closure (iVAC) is a method used for wound management, especially in high-risk surgical wounds. Pediatric neuromuscular patients are at high risk for infection or wound complications following spinal deformity correction. The goal of this study was to evaluate the effectiveness of iVAC therapy after PSF in pediatric neuromuscular scoliosis in preventing wound dehiscence and SSI as measured by the metric of unplanned return to the OR for infection in <90 days from the date of surgery. Methods: We reviewed all nonambulatory patients with neuromuscular scoliosis who underwent PSF at a single, large tertiary care pediatric hospital from 2019 to 2024. Ambulatory patients with neuromuscular disease were excluded. During this period of time, a consistent SSI prevention protocol was active and remained similar for all spine surgeons at our institution. Patients were placed into 1 of 2 groups based on whether they had an iVAC placed at the index procedure, and postoperative outcomes were examined. Results: A total of 134 patients [71 (53%) male and 63 (47%) female] with a mean age of 13.5 +/- 3.1 years at the time of surgery were included. Unplanned return to the operating room (UPROR) for suspected infection (<90 d) occurred among 7 (7.3%) patients with iVAC versus 8 (21.0%) without. UPROR was 2.9 times higher without iVAC (P=0.023). Only one (2.2%) patient faced infection among those sent home with the iVAC [P=0.020 (vs. either iVAC in the hospital or no iVAC)]. The number needed to treat with iVAC treatment to prevent one UPROR was 7.3. Conclusion: iVAC is a clinically useful, low-cost, low-morbidity tool in the fight against NM infection. Any duration of use of the iVAC following neuromuscular PSF appears to be associated with a lower incidence of infection.
C1 [Regan, Maia D.; Freeman, Colby M.; Talathi, Nakul; Spiegel, David A.; Flynn, John M.; Baldwin, Keith D.] Childrens Hosp Philadelphia, Orthopaed Ctr, 3401 Civ Ctr Blvd, Philadelphia, PA 19104 USA.
C3 University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of
   Philadelphia
RP Baldwin, KD (通讯作者)，Childrens Hosp Philadelphia, Orthopaed Ctr, 3401 Civ Ctr Blvd, Philadelphia, PA 19104 USA.
EM Maia.Regan@quinnipiac.edu; freemanc4@chop.edu; nstalathi@gmail.com;
   spiegeld@chop.edu; flynnj@chop.edu; baldwink@email.chop.edu
RI Freeman, Colby/NLO-5973-2025
OI Freeman, Colby/0009-0004-1407-5641
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
   Aleissa S, 2011, CAN J SURG, V54, P263, DOI 10.1503/cjs.008210
   Anari JB, 2015, WORLD J ORTHOP, V6, P564, DOI 10.5312/wjo.v6.i8.564
   Badin D, 2023, JBJS OPEN ACCESS, V8, DOI 10.2106/JBJS.OA.22.00123
   Chen Z, 2022, EUR SPINE J, V31, P1546, DOI 10.1007/s00586-022-07178-y
   Clark CE, 1999, SPINE, V24, P1909, DOI 10.1097/00007632-199909150-00008
   Dyck BA, 2019, J NEUROSURG-SPINE, V31, P430, DOI 10.3171/2019.2.SPINE18947
   Gomoll AH, 2006, J ORTHOP TRAUMA, V20, P705, DOI 10.1097/01.bot.0000211159.98239.d2
   Grosman R, 2002, Acta Chir Orthop Traumatol Cech, V69, P175
   JEVSEVAR DS, 1993, J BONE JOINT SURG AM, V75A, P880, DOI 10.2106/00004623-199306000-00008
   Lee R, 2018, EUR SPINE J, V27, P2536, DOI 10.1007/s00586-018-5612-2
   Mascarenhas DC, 2023, ORTHOPEDICS, V46, P373, DOI 10.3928/01477447-20230329-03
   Master DL, 2011, SPINE, V36, pE179, DOI 10.1097/BRS.0b013e3181db7afe
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   Pérez-Acevedo G, 2024, INT WOUND J, V21, DOI 10.1111/iwj.70034
   Rihn JA, 2008, SPINE, V33, P289, DOI 10.1097/BRS.0b013e318162016e
   Santosa KB, 2020, J SURG RES, V254, P197, DOI 10.1016/j.jss.2020.04.025
   Sponseller PD, 2000, SPINE, V25, P2461, DOI 10.1097/00007632-200010010-00007
   Szöke G, 1998, J PEDIATR ORTHOPED, V18, P727, DOI 10.1097/00004694-199811000-00006
   White AJ, 2022, BIOENGINEERING-BASEL, V9, DOI 10.3390/bioengineering9110614
NR 20
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0271-6798
EI 1539-2570
J9 J PEDIATR ORTHOPED
JI J. Pediatr. Orthop.
PD MAY-JUN
PY 2026
VL 46
IS 5
BP e475
EP e479
DI 10.1097/BPO.0000000000003220
PG 5
WC Orthopedics; Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Pediatrics
GA GF6ED
UT WOS:001735239900017
PM 41556273
DA 2026-07-24
ER

PT J
AU Rajabaleyan, P
   Cuk, P
   Möller, S
   Qvist, N
   Ellebaek, MB
AF Rajabaleyan, Pooya
   Cuk, Pedja
   Moller, Soren
   Qvist, Niels
   Ellebaek, Mark Bremholm
TI Vacuum-assisted closure or primary closure with relaparotomy on-demand
   in patients with secondary peritonitis: a systematic review and
   meta-analysis
SO WORLD JOURNAL OF EMERGENCY SURGERY
LA English
DT Review
DE Secondary peritonitis; Vacuum-assisted abdominal closure; Open abdomen
ID PRESSURE WOUND THERAPY; TEMPORARY ABDOMINAL CLOSURE; TOPICAL
   NEGATIVE-PRESSURE; OPEN ABDOMEN TREATMENT; PLANNED RELAPAROTOMY;
   INTRAABDOMINAL SEPSIS; FASCIAL CLOSURE; SEPTIC PATIENTS; LAPAROSTOMY;
   MANAGEMENT
AB Background Secondary peritonitis is a serious condition with significant morbidity and mortality. Its management requires emergency laparotomy for source control. Vacuum-assisted closure (VAC) and primary abdominal closure (PAC) are the main strategies for managing the laparostomy after source control. Despite the increasing use of VAC, concerns persist regarding its complications and long-term outcomes compared with PAC. Methods This systematic review followed PRISMA 2020 and MOOSE. The Cochrane Risk of Bias (RoB 2) tool, MINORS and GRADE framework assessed study quality and evidence certainty. The protocol was registered in PROSPERO (CRD42022304724). A comprehensive search of MEDLINE, Embase, and the Cochrane Library from January 2004 to August 2024 identified studies reporting postoperative outcomes following VAC or PAC after laparotomy for secondary peritonitis. The included studies had to report at least two key outcomes: mortality, postoperative complications, incisional hernia, secondary fascial closure, and hospital or intensive care unit (ICU) length of stay. Results Thirty-three studies including 4,520 patients were analyzed. Mortality was 31.1% in VAC and 22.2% in PAC (p = 0.327). Postoperative complications were higher with VAC (71.0% vs. 39.3%, p = 0.001). Incisional hernia rates were similar (21.3% vs. 20.8%, p = 0.958). Secondary fascial closure rate was significantly lower with VAC (58.1% vs. 85.9%, p < 0.001). VAC patients had longer ICU stays (21.1 vs. 9.7 days, p = 0.04), while hospital stay did not differ. Most studies had a high risk of bias, and GRADE assessment showed low to very low evidence certainty. Conclusion VAC therapy was associated with more postoperative complications, a lower fascial closure rate, and a longer ICU length of stay compared with PAC. Thirty-day mortality rates did not differ between the approaches. However, most of studies included were subject to serious risk of bias and a low level of certainty in evidence.
C1 [Rajabaleyan, Pooya; Cuk, Pedja; Qvist, Niels; Ellebaek, Mark Bremholm] Odense Univ Hosp, Res Unit Surg, Odense, Denmark.
   [Rajabaleyan, Pooya; Cuk, Pedja; Qvist, Niels; Ellebaek, Mark Bremholm] Univ Southern Denmark, Odense, Denmark.
   [Moller, Soren] Odense Univ Hosp, Open Patient Data Explorat Network OPEN, Odense, Denmark.
   [Rajabaleyan, Pooya; Cuk, Pedja; Qvist, Niels; Ellebaek, Mark Bremholm] Univ Southern Denmark, Dept Clin Res, DK-5000 Odense C, Denmark.
C3 University of Southern Denmark; Odense University Hospital; University
   of Southern Denmark; University of Southern Denmark; Odense University
   Hospital; University of Southern Denmark
RP Rajabaleyan, P (通讯作者)，Odense Univ Hosp, Res Unit Surg, Odense, Denmark.; Rajabaleyan, P (通讯作者)，Univ Southern Denmark, Odense, Denmark.; Rajabaleyan, P (通讯作者)，Univ Southern Denmark, Dept Clin Res, DK-5000 Odense C, Denmark.
EM Pooya.Rajabaleyan@skane.se; Pedja.Cuk@rsyd.dk; Soren.Moller@rsyd.dk;
   famqvist@dadlnet.dk; Mark.Ellebaek1@rsyd.dk
RI ; Möller, Sören/X-8738-2019
OI Cuk, Pedja/0000-0003-0582-604X; Möller, Sören/0000-0003-0858-4269;
   Ellebaek, Mark Bremholm/0000-0001-6550-7505; Rajabaleyan,
   Pooya/0000-0002-6882-9427
FU Novo Nordisk Fonden [NNF19OC0058637] Funding Source: Medline
CR Adkins AL, 2004, AM SURGEON, V70, P137
   Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
   Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
   Bader FG, 2009, EUR J MED RES, V14, P491, DOI 10.1186/2047-783X-14-11-491
   Bensignor T, 2018, WORLD J SURG, V42, P3589, DOI 10.1007/s00268-018-4687-6
   Berg A, 2022, LANGENBECK ARCH SURG, V407, P259, DOI 10.1007/s00423-021-02304-8
   Bertelsen CA, 2014, WORLD J SURG, V38, P774, DOI 10.1007/s00268-013-2360-7
   Bleszynski MS, 2016, AM J SURG, V211, P926, DOI 10.1016/j.amjsurg.2016.01.012
   Blot S, 2019, INTENS CARE MED, V45, P1703, DOI 10.1007/s00134-019-05819-3
   Bruhin A, 2014, INT J SURG, V12, P1105, DOI 10.1016/j.ijsu.2014.08.396
   Coccolini F, 2024, J TRAUMA ACUTE CARE, V96, pe39, DOI 10.1097/TA.0000000000004253
   Coccolini F, 2023, WORLD J EMERG SURG, V18, DOI 10.1186/s13017-023-00509-4
   Coccolini F, 2019, INJURY, V50, P160, DOI 10.1016/j.injury.2018.09.040
   Coccolini F, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0026-5
   Cumpston M, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.ED000142
   Fortelny RH, 2014, SURG ENDOSC, V28, P735, DOI 10.1007/s00464-013-3251-6
   Gasser E, 2021, FRONT SURG, V8, DOI 10.3389/fsurg.2021.632929
   Guyatt G, 2011, J CLIN EPIDEMIOL, V64, P383, DOI 10.1016/j.jclinepi.2010.04.026
   Horwood J, 2009, ANN ROY COLL SURG, V91, P681, DOI 10.1308/003588409X12486167520993
   Huston JM, 2024, SURG INFECT, V25, P419, DOI 10.1089/sur.2024.137
   Hutchins RR, 2004, WORLD J SURG, V28, P137, DOI 10.1007/s00268-003-7067-8
   Jannasch O, 2018, POL J SURG, V90, P27, DOI 10.5604/01.3001.0012.1751
   Kafka-Ritsch R, 2012, WORLD J SURG, V36, P1765, DOI 10.1007/s00268-012-1586-0
   Kao AM, 2019, J TRAUMA ACUTE CARE, V87, P623, DOI 10.1097/TA.0000000000002345
   Kirkpatrick AW, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0183-4
   Kirkpatrick AW, 2015, ANAESTH INTENSIVE TH, V47, pS63, DOI 10.5603/AIT.a2015.0081
   Kirkpatrick AW, 2013, INTENS CARE MED, V39, P1190, DOI 10.1007/s00134-013-2906-z
   Kunitatsu K, 2023, ANN MED SURG, V85, P645, DOI 10.1097/MS9.0000000000000334
   Lamme B, 2004, BJS-BRIT J SURG, V91, P1046, DOI 10.1002/bjs.4517
   Loftus TJ, 2017, J TRAUMA ACUTE CARE, V82, P345, DOI 10.1097/TA.0000000000001283
   Mintziras I, 2016, LANGENBECK ARCH SURG, V401, P619, DOI 10.1007/s00423-016-1443-y
   Müller V, 2020, ACTA CHIR BELG, V120, P179, DOI 10.1080/00015458.2019.1576448
   Mutafchiyski VM, 2016, J ROY ARMY MED CORPS, V162, P30, DOI 10.1136/jramc-2014-000386
   Olejnik J, 2007, BRATISL MED J, V108, P320
   Page Matthew J, 2021, Int J Surg, V88, P105906, DOI [10.1016/j.rec.2021.07.010, 10.1016/j.ijsu.2021.105906]
   Pliakos I, 2012, AM SURGEON, V78, P957
   Pliakos I, 2010, SURGERY, V148, P947, DOI 10.1016/j.surg.2010.01.021
   Poillucci G, 2021, EUR J TRAUMA EMERG S, V47, P1819, DOI 10.1007/s00068-020-01379-0
   Rajabaleyan P, 2025, WORLD J SURG, V49, P387, DOI 10.1002/wjs.12472
   Rajabaleyan P, 2023, BMC SURG, V23, DOI 10.1186/s12893-023-02179-0
   Rajabaleyan P, 2022, WORLD J EMERG SURG, V17, DOI 10.1186/s13017-022-00427-x
   Rakic M, 2005, CROAT MED J, V46, P957
   Richter S, 2013, GASTROENT RES PRACT, V2013, DOI 10.1155/2013/730829
   Robledo Felipe A, 2007, Surg Infect (Larchmt), V8, P63, DOI 10.1089/sur.2006.8.016
   Rosenzweig M, 2020, SURG INFECT, V21, P665, DOI 10.1089/sur.2019.272
   Ross JT, 2018, BMJ-BRIT MED J, V361, DOI 10.1136/bmj.k1407
   Sakr Y, 2018, OPEN FORUM INFECT DI, V5, DOI 10.1093/ofid/ofy313
   Sartelli M, 2024, WORLD J EMERG SURG, V19, DOI 10.1186/s13017-024-00552-9
   Sartelli M, 2021, WORLD J EMERG SURG, V16, DOI 10.1186/s13017-021-00387-8
   Sartelli M, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0141-6
   Sartelli M, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0132-7
   Sartelli M, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0055-0
   Sartelli M, 2014, WORLD J EMERG SURG, V9, DOI 10.1186/1749-7922-9-37
   Schmelzle M, 2010, DIGEST SURG, V27, P272, DOI 10.1159/000314609
   Slim K, 2003, ANZ J SURG, V73, P712, DOI 10.1046/j.1445-2197.2003.02748.x
   Sterne JAC, 2019, BMJ-BRIT MED J, V366, DOI 10.1136/bmj.l4898
   Stroup DF, 2000, JAMA-J AM MED ASSOC, V283, P2008, DOI 10.1001/jama.283.15.2008
   Szor DJ, 2024, J SURG ONCOL, V130, P945, DOI 10.1002/jso.27729
   Tao QS, 2014, GASTROENT RES PRACT, V2014, DOI 10.1155/2014/245182
   Tartaglia D, 2021, UPDATES SURG, V73, P1975, DOI 10.1007/s13304-021-01012-8
   Tolonen M, 2017, J TRAUMA ACUTE CARE, V82, P1100, DOI 10.1097/TA.0000000000001452
   Tridente A, 2014, INTENS CARE MED, V40, P202, DOI 10.1007/s00134-013-3158-7
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   van Ruler O, 2007, JAMA-J AM MED ASSOC, V298, P865, DOI 10.1001/jama.298.8.865
   van Ruler O, 2007, CRIT CARE MED, V35, P468, DOI 10.1097/01.CCM.0000253399.03545.2D
   van Ruler O, 2011, BMC SURG, V11, DOI 10.1186/1471-2482-11-38
   Willms AG, 2022, HERNIA, V26, P61, DOI 10.1007/s10029-020-02336-x
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
NR 68
TC 1
Z9 3
U1 0
U2 1
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-7922
J9 WORLD J EMERG SURG
JI World J. Emerg. Surg.
PD MAY 22
PY 2025
VL 20
IS 1
AR 42
DI 10.1186/s13017-025-00615-5
PG 21
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA 2WB9U
UT WOS:001492702100001
PM 40399929
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Hersh, RE
   Kaza, AK
   Long, SM
   Fiser, SM
   Drake, DB
   Tribble, CG
AF Hersh, RE
   Kaza, AK
   Long, SM
   Fiser, SM
   Drake, DB
   Tribble, CG
TI A technique for the treatment of sternal infections using the Vacuum
   Assisted Closure™ device
SO HEART SURGERY FORUM
LA English
DT Article
ID PREVENTABLE COMPLICATION; NEGATIVE-PRESSURE; WOUND CONTROL; MUSCLE
   FLAPS; EXPERIENCE; MEDIASTINITIS
AB Background: Sternal infections after median sternotomy remain a serious cause of postoperative morbidity and mortality. The treatment of sternal infections has evolved over the past few decades, and now aggressive surgical debridement with rotational muscle flap closure has provided an acceptable means of managing this complication. However, there are several disadvantages with this approach, mainly related to the morbidity associated with serial debridements with dressing changes and open packing until the wound is closed. Other disadvantages include potential morbidity and mortality associated with the shearing forces between the beating heart and the debrided sternal edges, and the need to paralyze the patient during the period after debridement.
   Methods: Our method of managing sternal infections is based on the triad of prompt surgical debridement, serial quantitative wound cultures, and the use of the Vacuum Assisted Closure(TM) (VAC) device (KCI International, San Antonio, TX). Following debridement and irrigation, a biopsy of the healthy appearing bone is sent for quantitative culture. If culture results are favorable, the wound is then fitted with the VAC(TM) device, which consists of a non-collapsible, open-cell, polyurethane sponge with embedded vacuum tubing, a vacuum pump, and transparent adhesive dressing. When systemic signs of infection and quantitative cultures indicate the resolution of the local infection, regional muscle flap or primary wound closure is performed.
   Conclusions: The VAC(TM) serves as a bridge to sternal wound closure and is a safe and effective therapeutic strategy for patients with impaired physiologic reserve and/or highly contaminated wounds. We feel that it is also reasonable to consider the VAC(TM) as a preventive strategy against right ventricular rupture. Furthermore, because the firmness of the vacuum sponge apparatus acts as an impressive sternal stabilizer, post-debridement extubation is possible, reducing the need for prolonged paralysis and mechanical ventilation. This stabilization also allows early postoperative ambulation with the VAC(TM) in place. In summary, we believe that the VAC(TM) device offers an effective means of managing patients with sternal infections.
C1 Univ Virginia Hlth Syst, Div Thorac & Cardiovasc Surg, Dept Surg, Charlottesville, VA 22908 USA.
   Univ Virginia Hlth Syst, Dept Plast Surg, Charlottesville, VA 22908 USA.
C3 University of Virginia; University of Virginia (UVA) Health System;
   University of Virginia; University of Virginia (UVA) Health System
RP Tribble, CG (通讯作者)，Univ Virginia Hlth Syst, Div Thorac & Cardiovasc Surg, Dept Surg, POB 801359, Charlottesville, VA 22908 USA.
EM ctribble@virginia.edu
RI Kaza, Aditya/AAE-2116-2019
OI Kaza, Aditya/0000-0003-3450-4496
CR Arbulu A, 1996, EUR J CARDIO-THORAC, V10, P110, DOI 10.1016/S1010-7940(96)80132-1
   Argenta L, 1993, JOINT M WOUND HEAL S
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1994, 73 ANN M AM ASS PLAS
   Baskett RJF, 1999, ANN THORAC SURG, V67, P462, DOI 10.1016/S0003-4975(98)01195-3
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Genecov DG, 1998, ANN PLAS SURG, V40, P219, DOI 10.1097/00000637-199803000-00004
   Hersh RE, 2001, ANN PLAS SURG, V46, P250, DOI 10.1097/00000637-200103000-00008
   Jones G, 1997, ANN SURG, V225, P766, DOI 10.1097/00000658-199706000-00014
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   LOOP FD, 1990, ANN THORAC SURG, V49, P179, DOI 10.1016/0003-4975(90)90136-T
   MILANO CA, 1995, CIRCULATION, V92, P2245, DOI 10.1161/01.CIR.92.8.2245
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   Schumaker Jr H.B., 1963, ARCH SURG-CHICAGO, V86, P384
   Smith LA, 1997, AM SURGEON, V63, P1102
NR 16
TC 19
Z9 24
U1 0
U2 3
PU FORUM MULTIMEDIA PUBLISHING, LLC
PI CHARLOTTESVILLE
PA 375 GREENBRIER DR, CHARLOTTESVILLE, VA 22901 USA
SN 1098-3511
J9 HEART SURG FORUM
JI Heart Surg. Forum
PY 2001
VL 4
IS 3
BP 211
EP 215
AR 2001-43986
PG 5
WC Cardiac & Cardiovascular Systems; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Surgery
GA 474UZ
UT WOS:000171126400003
PM 11673139
DA 2026-07-24
ER

PT J
AU Choi, HJ
AF Choi, Hwan Jun
TI Cervical Necrotizing Fasciitis Resulting in Acupuncture and Herbal
   Injection for Submental Lipoplasty
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Acupuncture; complication; necrotizing fasciitis; wound infection;
   trauma
ID INFECTION; MEDICINE; PATIENT
AB Acupuncture is used for some conditions as an alternative to medication or surgical intervention. Several complications had been reported, and they are generally due to physical injury by the needle or transmission of diseases. Necrotizing fasciitis is an uncommon infection, but potentially lethal, especially when associated with systemic disorders such as diabetes. The authors report a case of serious cervical necrotizing fasciitis that developed after acupuncture and herbal injection treatment of fat accumulation of the submental area in a 32-year-old healthy woman. She presented with discharging wound over the submental area. The initial diagnosis was based on clinical information, in which localized necrosis areas in the cervical and chin regions were observed. Wide antibiotic therapy was applied, followed by surgical drainage, debridement, and negative pressure wound therapy. Culture was positive for Serratia liquefaciens and Staphylococcus intermedius. She made a good recovery.
C1 [Choi, Hwan Jun] Soonchunhyang Univ, Dept Plast & Reconstruct Surg, Coll Med, Cheonan, South Korea.
C3 Soonchunhyang University
RP Choi, HJ (通讯作者)，Soonchunhyang Univ, Cheonan Hosp, Dept Plast & Reconstruct Surg, 23-20 Byeongmyeong Dong, Cheonan Si 330721, Chuncheongnam D, South Korea.
EM medi619@hanmail.net
FU Soonchunhyang University Research Fund
FX This work was supported by the Soonchunhyang University Research Fund.
CR Antunes AA, 2013, J CRANIOFAC SURG, V24, pE594, DOI 10.1097/SCS.0b013e31829ad57b
   Buchanan PJ, 2013, ANN PLAS SURG, V70, P739, DOI 10.1097/SAP.0b013e31823fac60
   EISENBERG DM, 1993, NEW ENGL J MED, V328, P246, DOI 10.1056/NEJM199301283280406
   FISHER P, 1994, BMJ-BRIT MED J, V309, P107, DOI 10.1136/bmj.309.6947.107
   Hama Y, 2004, ARCH NEUROL-CHICAGO, V61, P1608, DOI 10.1001/archneur.61.10.1608
   Hsieh RL, 2011, J ALTERN COMPLEM MED, V17, P871, DOI 10.1089/acm.2010.0617
   Kim JH, 2011, YONSEI MED J, V52, P207, DOI 10.3349/ymj.2011.52.1.207
   Konstantinov IE, 2008, ANN THORAC SURG, V86, P1973, DOI 10.1016/j.athoracsur.2008.05.004
   Lee S, 2008, YONSEI MED J, V49, P322, DOI 10.3349/ymj.2008.49.2.322
   Matsuyama H, 1998, J UROLOGY, V159, P2087, DOI 10.1016/S0022-5347(01)63262-2
   Mohammedi I, 1999, INTENS CARE MED, V25, P829, DOI 10.1007/s001340050959
   Niggemann B, 2003, ALLERGY, V58, P707, DOI 10.1034/j.1398-9995.2003.00219.x
   Park JH, 2005, J THORAC CARDIOV SUR, V130, P210, DOI 10.1016/j.jtcvs.2004.11.046
   RAMPES H, 1999, ACUPUNCTURE SCI APPR, P128
   Saw A., 2004, SMJ Singapore Medical Journal, V45, P180
   Sierpina VS, 2005, SOUTH MED J, V98, P330, DOI 10.1097/01.SMJ.0000140834.30654.0F
   Umeda M, 2003, ORAL SURG ORAL MED O, V95, P283, DOI 10.1067/moe.2003.85
   White Adrian, 2004, Acupunct Med, V22, P122
NR 18
TC 7
Z9 9
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD SEP
PY 2014
VL 25
IS 5
BP E507
EP E509
DI 10.1097/SCS.0000000000001120
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AP2VK
UT WOS:000341933600040
PM 25148627
DA 2026-07-24
ER

PT J
AU Yang, JZ
   Xiao, CS
   Wen, HL
   Sun, K
   Wu, XM
   Feng, XS
AF Yang, Jingzhe
   Xiao, Changshuan
   Wen, Hailing
   Sun, Kui
   Wu, Xiaoming
   Feng, Xinshu
TI 被撤回的出版物: Effect Evaluation of Platelet-Rich Plasma Combined with Vacuum
   Sealing Drainage on Serum Inflammatory Factors in Patients with Pressure
   Ulcer by Intelligent Algorithm-Based CT Image (Retracted Article)
SO COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
LA English
DT Article; Retracted Publication
ID CARE
AB This work was to explore the efficacy of intelligent algorithm-based computed tomography (CT) to evaluate platelet-rich plasma (PRP) combined with vacuum sealing drainage (VSD) in the treatment of patients with pressure ulcers. Based on the u-net network structure, an image denoising algorithm based on double residual convolution neural network (Dr-CNN) was proposed to denoise the CT images. A total of 84 patients who were hospitalized in hospital were randomly divided into group A (without any intervention), group B (PRP treatment), group C (VSD treatment), and group D (PRP+VSD treatment). Procalcitonin (PCT) was detected by enzyme-linked immunosorbent assay (ELISA) combined with immunofluorescence method, C-reactive protein (CRP) was detected by rate reflectance turbidimetry (RRT), and interleukin-6 (IL-6) was detected by electrochemiluminescence method. The results showed that after treatment, 44 cases (52.38%) of pressure ulcers patients recovered, 24 cases (28.57%) had no change in stage, and 16 cases (19.04%) developed pressure ulcers. The pain scores of group D at 1 week (3.35 +/- 0.56 points) and 2 weeks (2.76 & PLUSMN;0.55 points) after treatment were significantly lower than those in group C (7.77 +/- 0.58 points and 6.34 +/- 0.44 points, respectively). The time of complete wound healing in group D (24.5 +/- 2.32) was obviously lower in contrast to that in groups A, B, and C (35.54 +/- 3.22 days, 30.23 +/- 2 days, and 29.34 +/- 2.15 days, respectively). In addition, the medical satisfaction of group D (8.74 +/- 0.69) was significantly higher than that of groups A, B, and C (4.69 +/- 0.85, 5.22 +/- 0.31, and 5.18 +/- 0.59, respectively). The levels of IL-6 and PCT in group D were lower than those in groups A, B, and C, and the differences were statistically significant (P < 0.01). The average values of peak signal to noise ratio (PSNR) and structural similarity index measure (SSIM) of the Dr-CNN network model were 37.21 +/- 1.09 dB and 0.925 +/- 0.01, respectively, which were higher than other algorithms. The mean values of root mean square error (MSE) and normalized mean absolute distance (NMAD) of the Dr-CNN network model were 0.022 +/- 0.002 and 0.126 +/- 0.012, respectively, which were significantly lower than other algorithms (P < 0.05). The experimental results showed that PrP combined with VSD could significantly reduce the inflammatory response of patients with pressure ulcers. PRP combined with VSD could significantly reduce the pain of dressing change for patients. Moreover, the performance model of image denoising algorithm based on double residual convolutional neural network was better than other algorithms.
C1 [Yang, Jingzhe; Xiao, Changshuan; Wen, Hailing; Sun, Kui; Wu, Xiaoming; Feng, Xinshu] Chengde Med Univ, Dept Burn & Plast Surg, Affiliated Hosp, Chengde 067000, Hebei, Peoples R China.
C3 Chengde Medical University
RP Yang, JZ (通讯作者)，Chengde Med Univ, Dept Burn & Plast Surg, Affiliated Hosp, Chengde 067000, Hebei, Peoples R China.
EM yangjingzhe@cdmc.edu.cn
RI feng, xinshu/NDS-7041-2025
CR Blenman Juliet, 2017, Br J Nurs, V26, pS16, DOI [10.12968/bjon.2017.26.6.s16, 10.12968/bjon.2017.26.6.S16]
   C Anam, 2020, J Biomed Phys Eng, V10, P623, DOI [10.31661/jbpe.v0i0.2002-1072, 10.31661/jbpe.v0i0.2002-1072]
   Caribé PRRV, 2019, EJNMMI PHYS, V6, DOI 10.1186/s40658-019-0264-9
   Collier Mark, 2016, Acta Med Croatica, V70 Suppl 1, P3
   Fremmelevholm Aase, 2019, Br J Nurs, V28, pS6, DOI [10.12968/bjon.2019.28.6.s6, 10.12968/bjon.2019.28.6.S6]
   Hesseler MJ, 2019, J AM ACAD DERMATOL, V81, P834, DOI 10.1016/j.jaad.2019.04.037
   Higaki T, 2019, JPN J RADIOL, V37, P73, DOI 10.1007/s11604-018-0796-2
   Kim B, 2019, MED PHYS, V46, P3906, DOI 10.1002/mp.13713
   Kim Y, 2020, SENSORS-BASEL, V20, DOI 10.3390/s20123494
   Kottner J, 2020, J TISSUE VIABILITY, V29, P197, DOI 10.1016/j.jtv.2020.04.003
   Kottner J, 2019, J TISSUE VIABILITY, V28, P51, DOI 10.1016/j.jtv.2019.01.001
   Serrano ML, 2017, MED INTENSIVA, V41, P339, DOI 10.1016/j.medin.2016.09.003
   Liu Q, 2021, CLINICS, V76, DOI 10.6061/clinics/2021/e2355
   Mervis JS, 2019, J AM ACAD DERMATOL, V81, P881, DOI 10.1016/j.jaad.2018.12.069
   Mervis JS, 2019, J AM ACAD DERMATOL, V81, P893, DOI 10.1016/j.jaad.2018.12.068
   Ramos-Torrecillas J, 2015, BIOL RES NURS, V17, P152, DOI 10.1177/1099800414535840
   Sanchez-Avila RM, 2020, EUR J OPHTHALMOL, V30, P94, DOI 10.1177/1120672118818943
   Sell SA, 2011, J SPINAL CORD MED, V34, P122, DOI 10.1179/107902610X12923394765616
   Shi CH, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0192707
   Sumarno Adi Subrata, 2019, Br J Community Nurs, V24, pS38, DOI [10.12968/bjcn.2019.24.sup12.s38, 10.12968/bjcn.2019.24.Sup12.S38]
   Uçar Ö, 2020, INT WOUND J, V17, P831, DOI 10.1111/iwj.13344
   Vagal A, 2019, NEUROLOGY, V93, P888, DOI 10.1212/WNL.0000000000008481
   Volakakis E, 2019, WOUNDS, V31, P252
   Wang X, 2019, SENSORS-BASEL, V19, DOI 10.3390/s19112462
   Wang Ying, 2017, Zhongguo Ying Yong Sheng Li Xue Za Zhi, V33, P181, DOI 10.12047/j.cjap.5425.2017.046
   Willemink MJ, 2019, EUR RADIOL, V29, P2185, DOI 10.1007/s00330-018-5810-7
   Xia YJ, 2019, PLAST RECONSTR SURG, V144, P1463, DOI 10.1097/PRS.0000000000006281
NR 27
TC 8
Z9 8
U1 1
U2 11
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1748-670X
EI 1748-6718
J9 COMPUT MATH METHOD M
JI Comput. Math. Method Med.
PD MAR 2
PY 2022
VL 2022
AR 8916076
DI 10.1155/2022/8916076
PG 11
WC Mathematical & Computational Biology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Mathematical & Computational Biology
GA 0H4HB
UT WOS:000778693300003
PM 35281950
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Ripamonti, B
   Raia-Barjat, T
   Chauleur, C
   Mathevet, P
AF Ripamonti, B.
   Raia-Barjat, T.
   Chauleur, C.
   Mathevet, P.
TI How do I prevent caesarean wound infections in obese patients in 2017?
SO GYNECOLOGIE OBSTETRIQUE FERTILITE & SENOLOGIE
LA French
DT Review
DE Obesity; Pregnancy; Wound infections; Cesarean section
ID SURGICAL SITE INFECTION; NEGATIVE-PRESSURE THERAPY; PERIOPERATIVE
   OXYGEN; MATERNAL OBESITY; RISK-FACTORS; DELIVERY; COMPLICATIONS;
   SECTION; WOMEN; PROPHYLAXIS
AB Obesity is an important risk factor of cesarean section and is associated with an increased risk of wound complications such as infections. This review focuses on the available strategies to limit complications in this population. Choice of antiseptic solution, appropriate dose and type of antibiotic prophylaxy, suture closure of subcutaneous fat, suture skin closure and closed incision negative pressure wound therapy may reduce the risk of wound infections associated with cesarean section in obese patients. Vaginal desinfection, plastic adhesive draps, high-concentration supplemental perioperative oxygen, use of a barrier retractor, wound drainage and type of skin incision are discussed in this review. Clinical trials of good quality are needed to improve our clinical practice. (c) 2017 Elsevier Masson SAS. All rights reserved.
C1 [Ripamonti, B.; Raia-Barjat, T.; Chauleur, C.] Univ Hosp, Dept Gynecol & Obstet, St Etienne, France.
   [Raia-Barjat, T.; Chauleur, C.] Univ Jean Monnet, Res Unit EA3065, F-42023 St Etienne, France.
   [Mathevet, P.] Univ Lausanne, Univ Hosp, Gynecol Dept, Lausanne, Switzerland.
C3 CHU de St Etienne; University of Lausanne; Centre Hospitalier
   Universitaire Vaudois (CHUV)
RP Ripamonti, B (通讯作者)，Univ Hosp, Dept Gynecol & Obstet, St Etienne, France.
EM bertripa@hotmail.com; tiphaine.barjat@chu-st-etienne.fr;
   celine.chauleur@chu-st-etienne.fr; patrice.mathevet@chuv.ch
RI ; Raia-Barjat, Tiphaine/AAJ-7310-2021
OI CHAULEUR, celine/0000-0003-4057-8133; Raia-Barjat,
   Tiphaine/0000-0002-4408-6075
CR Ahmadzia HK, 2015, OBSTET GYNECOL, V126, P708, DOI 10.1097/AOG.0000000000001064
   Ahmed MR, 2017, J MATERN-FETAL NEO M, V30, P1484, DOI 10.1080/14767058.2016.1219996
   Al-Inany H, 2002, GYNECOL OBSTET INVES, V53, P75, DOI 10.1159/000052996
   Basha SL, 2010, AM J OBSTET GYNECOL, V203, DOI 10.1016/j.ajog.2010.07.011
   Bratzler Dale W, 2013, Am J Health Syst Pharm, V70, P195, DOI [10.2146/ajhp120568, 10.1089/sur.2013.9999]
   Brocato BE, 2013, J PREGNANCY, V2013, DOI 10.1155/2013/890296
   Chaboyer W, 2014, HEALTHCARE, V2, P417, DOI 10.3390/healthcare2040417
   Chelmow D, 2004, OBSTET GYNECOL, V103, P974, DOI 10.1097/01.AOG.0000124807.76451.47
   Childress KMS, 2016, AM J OBSTET GYNECOL, V214, DOI 10.1016/j.ajog.2015.09.096
   Chu SY, 2007, OBES REV, V8, P385, DOI 10.1111/j.1467-789X.2007.00397.x
   Clay FSH, 2011, AM J OBSTET GYNECOL, V204, P378, DOI 10.1016/j.ajog.2010.11.018
   Conner SN, 2014, AM J PERINAT, V31, P299, DOI 10.1055/s-0033-1348402
   CORDTZ T, 1989, J HOSP INFECT, V13, P267, DOI 10.1016/0195-6701(89)90007-8
   Darouiche RO, 2010, NEW ENGL J MED, V362, P18, DOI 10.1056/NEJMoa0810988
   Duggal N, 2013, OBSTET GYNECOL, V122, P79, DOI 10.1097/AOG.0b013e318297ec6c
   Edwards JP, 2012, ANN SURG, V256, P53, DOI 10.1097/SLA.0b013e3182570372
   Figueroa D, 2013, OBSTET GYNECOL, V121, P33, DOI [10.1097/AOG.0b013e31827a072c, 10.1097/aog.0b013e31827a072c]
   Gardella C, 2008, OBSTET GYNECOL, V112, P545, DOI 10.1097/AOG.0b013e318182340c
   Gates S, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004549.pub3
   Haas D M, 2014, COCHRANE DATABASE SY, pCD007892
   Houston MC, 2000, AM J OBSTET GYNECOL, V182, P1033, DOI 10.1067/mob.2000.105400
   Klingel ML, 2013, INT J OBSTET ANESTH, V22, P104, DOI 10.1016/j.ijoa.2013.01.001
   Kugler NW, 2016, J SURG RES, V203, P491, DOI 10.1016/j.jss.2016.04.032
   Mackeen AD, 2015, AM J OBSTET GYNECOL, V212, DOI 10.1016/j.ajog.2014.12.020
   Maggio L, 2015, OBSTET GYNECOL, V125, P1205, DOI 10.1097/AOG.0000000000000789
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Mark KS, 2014, SURG INNOV, V21, P345, DOI 10.1177/1553350613503736
   Marrs CC, 2014, AM J OBSTET GYNECOL, V210, DOI 10.1016/j.ajog.2014.01.018
   McLean M, 2012, AM J PERINAT, V29, P301, DOI 10.1055/s-0031-1295637
   NAUMANN RW, 1995, OBSTET GYNECOL, V85, P412, DOI 10.1016/0029-7844(94)00427-F
   Robinson HE, 2005, OBSTET GYNECOL, V106, P1357, DOI 10.1097/01.AOG.0000188387.88032.41
   Schneid-Kofman N, 2005, INT J GYNECOL OBSTET, V90, P10, DOI 10.1016/j.ijgo.2005.03.020
   Scifres C, 2011, AM J OBSTET GYNECOL, V204, pS263, DOI 10.1016/j.ajog.2010.10.687
   Smaill FM, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD007482.pub3
   Swank ML, 2015, AM J OBSTET GYNECOL, V213, DOI 10.1016/j.ajog.2015.05.030
   Swift SH, 2015, J REPROD MED, V60, P211
   Tita ATN, 2016, NEW ENGL J MED, V375, P1231, DOI 10.1056/NEJMoa1602044
   Tuuli MG, 2016, NEW ENGL J MED, V374, P647, DOI 10.1056/NEJMoa1511048
   Wall PD, 2003, OBSTET GYNECOL, V102, P952, DOI 10.1016/S0029-7844(03)00861-5
   Ward HRG, 2001, J HOSP INFECT, V47, P230, DOI 10.1053/jhin.2000.0843
   Williams NL, 2013, AM J PERINAT, V30, P779, DOI 10.1055/s-0032-1333405
   Wloch C, 2012, BJOG-INT J OBSTET GY, V119, P1324, DOI 10.1111/j.1471-0528.2012.03452.x
   Zaki MN, 2016, J PERINATOL, V36, P819, DOI 10.1038/jp.2016.89
NR 43
TC 0
Z9 0
U1 0
U2 4
PU ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
PI ISSY-LES-MOULINEAUX
PA 65 RUE CAMILLE DESMOULINS, CS50083, 92442 ISSY-LES-MOULINEAUX, FRANCE
SN 2468-7197
EI 2468-7189
J9 GYNECOL OBST FERT SE
JI Gynecol. Obstet. Fertil. Senol.
PD NOV
PY 2017
VL 45
IS 11
BP 619
EP 622
DI 10.1016/j.gofs.2017.08.006
PG 4
WC Obstetrics & Gynecology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Obstetrics & Gynecology
GA FQ5JY
UT WOS:000418396300008
PM 28964729
DA 2026-07-24
ER

PT J
AU Pandit, V
   Nesbitt, SR
   Kim, DY
   Mixon, A
   Kotha, SP
AF Pandit, Vaibhav
   Nesbitt, Sterling Robert
   Kim, Diana Y.
   Mixon, Amanda
   Kotha, Shiva P.
TI Combinatorial therapy using negative pressure and varying lithium dosage
   for accelerated wound healing
SO JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
LA English
DT Article
DE Wnt signaling; Piezoelectric vacuum pump; Murine fibroblasts;
   beta-catenin; Migration into score
ID BETA-CATENIN; SIZE
AB In this work, we investigated the effects of negative pressure, applied using a pump designed for Negative Pressure Wound Therapy (NPWT), on the process of wound healing in vitro via initiation of the Wnt signaling pathway. Results indicate that negative pressure enhanced Wnt signaling and migration into a simulated wound in vitro in NIH-3T3 murine fibroblast cells. Increasing doses of lithium (upto 15 mM) increased basal Wnt signaling and enhanced cell migration into the simulated wound site. A combination of negative pressure and increased doses of lithium synergistically increased Wnt signaling and demonstrated further enhanced cell migration into simulated wound sites, with maximal filling of the simulated wound observed at lithium concentrations of at least 10 mM. (C) 2015 Elsevier Ltd. All rights reserved.
C1 [Pandit, Vaibhav; Nesbitt, Sterling Robert; Kim, Diana Y.; Mixon, Amanda; Kotha, Shiva P.] Rensselaer Polytech Inst, Dept Biomed Engn, Ctr Biotechnol & Interdisciplinary Studies, Troy, NY 12180 USA.
C3 Rensselaer Polytechnic Institute
RP Pandit, V (通讯作者)，Rensselaer Polytech Inst, Dept Biomed Engn, Ctr Biotechnol & Interdisciplinary Studies, 110 8th St, Troy, NY 12180 USA.
EM pandiv@rpi.edu; sterling.nesbitt@gmail.com; kimd13@rpi.edu;
   mixona@rpi.edu; kothas2@rpi.edu
FU NY Capital Alliance Program; Rensselaer; NIH/NIA [R01 AG030637]
FX We would like to acknowledge funding provided by the NY Capital Alliance
   Program and start-up funding from Rensselaer. We would also like to
   acknowledge NIH/NIA R01 AG030637.
CR Amini-Nik S, 2014, J CLIN INVEST, V124, P2599, DOI 10.1172/JCI62059
   Amini-Nik S, 2011, STEM CELLS, V29, P1371, DOI 10.1002/stem.688
   Cheon SS, 2006, FASEB J, V20, P692, DOI 10.1096/fj.05-4759com
   Cheon SS, 2002, P NATL ACAD SCI USA, V99, P6973, DOI 10.1073/pnas.102657399
   DaVanzo JE, 2010, OSTOMY WOUND MANAG, V56, P44
   Fathke C, 2006, BMC CELL BIOL, V7, DOI 10.1186/1471-2121-7-4
   Gupta S, 2007, WOUNDS S, V19, pS1
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Lam AP, 2011, CURR OPIN RHEUMATOL, V23, P562, DOI 10.1097/BOR.0b013e32834b3309
   Orgill DP, 2011, PLAST RECONSTR SURG, V127, p105S, DOI 10.1097/PRS.0b013e318200a427
   Sen CK, 2009, WOUND REPAIR REGEN, V17, P763, DOI 10.1111/j.1524-475X.2009.00543.x
   Stojadinovic O, 2005, AM J PATHOL, V167, P59, DOI 10.1016/S0002-9440(10)62953-7
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Whyte J.L., 2012, COLD SPRING HARB PER, V4, P8
NR 14
TC 14
Z9 16
U1 0
U2 24
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 1751-6161
EI 1878-0180
J9 J MECH BEHAV BIOMED
JI J. Mech. Behav. Biomed. Mater.
PD APR
PY 2015
VL 44
BP 173
EP 178
DI 10.1016/j.jmbbm.2015.01.012
PG 6
WC Engineering, Biomedical; Materials Science, Biomaterials
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Materials Science
GA CD1LK
UT WOS:000350836200018
PM 25658877
DA 2026-07-24
ER

PT J
AU Schintler, MV
   Grohmann, M
   Donia, C
   Aberer, E
   Scharnagl, E
AF Schintler, Michael V.
   Grohmann, Martin
   Donia, Claudio
   Aberer, Elisabeth
   Scharnagl, Erwin
TI Management of an unfortunate triad after breast reconstruction: Pyoderma
   gangrenosum, full-thickness chest wall defect and Acinetobacter
   Baumannii Infection
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article; Proceedings Paper
CT 1st International Workshop on Wound Technology
CY JAN 18-19, 2009
CL Paris, FRANCE
DE Breast reconstruction; Post-surgical pyoderma gangrenosum; Chest wall
   infection; MDR; Acinetobacter baumannii; VAC Instill (R)
AB If diagnosed late, post-surgical pyoderma gangrenosum (PSPG) is a rare, tricky and potentially life-threatening complication. Once diagnosed, immunosuppressive agents may provoke further complications. Well-intentioned extensive serial debridement may cause deep skin and soft-tissue defects, requiring skin grafting and possible flap surgery. The combination of necessary immunosuppressive treatment, protracted hospital stay and broad-spectrum systemic antimicrobial therapy may encourage serious acquired multidrug resistance (MDR). We report an unfortunate triad following breast reconstruction of PSPG, full-thickness chest wall defect and MDR with Acinetobacter baumannii infection. Interdisciplinary treatment using free flap surgery and negative-pressure wound therapy with instillation therapy (V.A.C.Instill (R) Wound Therapy) enabled survival and complete wound closure. (C) 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
C1 [Schintler, Michael V.; Grohmann, Martin; Donia, Claudio; Scharnagl, Erwin] Med Univ Graz, Dept Surg, Div Plast Surg, A-8036 Graz, Austria.
   [Donia, Claudio] Univ Catania, Cannizzaro Hosp, Div Plast Surg, I-95126 Catania, Italy.
   [Aberer, Elisabeth] Med Univ Graz, Dept Dermatol, A-8036 Graz, Austria.
C3 Medical University of Graz; University of Catania; Medical University of
   Graz
RP Schintler, MV (通讯作者)，Med Univ Graz, Dept Surg, Div Plast Surg, Auenbruggerpl 29, A-8036 Graz, Austria.
EM michael.schintler@meduni-graz.at
CR Brocq L., 1916, ANN DERMATOL SYPHIL, V9, P1
   Brunsting LA, 1930, ARCH DERMATOL SYPH, V22, P655, DOI 10.1001/archderm.1930.01440160053009
   Horner B, 2004, BRIT J PLAST SURG, V57, P679, DOI 10.1016/j.bjps.2004.03.004
   Jain A, 2000, BRIT J PLAST SURG, V53, P437, DOI 10.1054/bjps.2000.3351
   LONG CC, 1992, BRIT J DERMATOL, V127, P45, DOI 10.1111/j.1365-2133.1992.tb14826.x
   Ouazzani A, 2007, ACTA CHIR BELG, V107, P424, DOI 10.1080/00015458.2007.11680088
   Powell FC, 1996, J AM ACAD DERMATOL, V34, P395, DOI 10.1016/S0190-9622(96)90428-4
   Rozen SM, 2001, ANN PLAS SURG, V47, P310, DOI 10.1097/00000637-200109000-00015
   Su WPD, 2004, INT J DERMATOL, V43, P790, DOI 10.1111/j.1365-4632.2004.02128.x
   Weenig RH, 2002, NEW ENGL J MED, V347, P1412, DOI 10.1056/NEJMoa013383
NR 10
TC 36
Z9 37
U1 0
U2 1
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD JUL
PY 2010
VL 63
IS 7
BP E564
EP E567
DI 10.1016/j.bjps.2009.12.013
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 609KV
UT WOS:000278656200028
PM 20153277
DA 2026-07-24
ER

PT J
AU Iurilli, M
   Guarini, LB
   Di Bella, S
   Zerbato, V
   Papa, G
AF Iurilli, Martin
   Guarini, Luigi Bonat
   Di Bella, Stefano
   Zerbato, Verena
   Papa, Giovanni
TI Cutaneous Scedosporium infection mimicking malignancy in a kidney
   transplant recipient: A case report
SO DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
LA English
DT Article
DE Scedosporium; Cutaneous infection; Kidney transplantation; Voriconazole;
   Case report
ID FUNGAL-INFECTIONS; APIOSPERMUM; SUSCEPTIBILITY; VORICONAZOLE; THERAPY
AB Background: Cutaneous Scedosporium infection represents an extremely rare opportunistic fungal complication in solid-organ transplant recipients, often mimicking post-transplant skin malignancies due to chronic immunosuppression. Case presentation: A 75-year-old woman, kidney transplanted in 2022 for IgA nephropathy on tacrolimus, mycophenolate, and prednisone, developed progressive firm nodular lesions on the left lower limb over two months. Punch biopsy revealed granulomatous inflammation with septate hyphae on Gomori-Grocott stain; culture confirmed Scedosporium spp. CT excluded dissemination. Conclusion: Voriconazole (6 mg/kg loading dose, then 4 mg/kg maintenance dose) combined with surgical debridement, negative-pressure wound therapy, and skin grafting achieved complete healing at three months, with no recurrence at 12 months. Early biopsy is crucial to differentiate this rare entity from squamous cell carcinoma, enabling multidisciplinary success.
C1 [Iurilli, Martin; Papa, Giovanni] Trieste Univ Hosp ASUGI, Plast & Reconstruct Surg Unit, Trieste, Italy.
   [Iurilli, Martin; Di Bella, Stefano; Papa, Giovanni] Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy.
   [Di Bella, Stefano; Zerbato, Verena] Trieste Univ Hosp ASUGI, Infect Dis Unit, Trieste, Italy.
C3 University of Trieste
RP Iurilli, M (通讯作者)，Cattinara Hosp, Plast & Reconstruct Surg Unit, Str Fiume 447, I-34149 Trieste, Italy.
EM martin.iurilli@phd.units.it
RI Di Bella, Stefano/K-8162-2016; Zerbato, Verena/KIH-8256-2024; Iurilli,
   Martin/OPO-3971-2025
OI Iurilli, Martin/0009-0007-4634-2582
CR Boyd ME, 2018, MED MYCOL CASE REP, V22, P52, DOI 10.1016/j.mmcr.2018.09.002
   Cortez KJ, 2008, CLIN MICROBIOL REV, V21, P157, DOI 10.1128/CMR.00039-07
   Granata S, 2023, FRONT MED-LAUSANNE, V10, DOI 10.3389/fmed.2023.1189680
   Husain S, 2005, CLIN INFECT DIS, V40, P89, DOI 10.1086/426445
   Jiang YY, 2020, CASE REP INFECT DIS, V2020, DOI 10.1155/2020/9727513
   Johnson LS, 2014, TRANSPL INFECT DIS, V16, P578, DOI 10.1111/tid.12244
   Katragkou A, 2007, MYCOSES, V50, P412, DOI 10.1111/j.1439-0507.2007.01388.x
   Khaddour K, 2024, CANCERS, V16, DOI 10.3390/cancers16173083
   Lackner M, 2014, ANTIMICROB AGENTS CH, V58, P5877, DOI 10.1128/AAC.03211-14
   Lackner M, 2012, ANTIMICROB AGENTS CH, V56, P2635, DOI 10.1128/AAC.05910-11
   Leek R, 2016, Case Reports in Transplantation, V2016, P1, DOI [10.1155/2016/1879529, 10.1155/2016/1879529, DOI 10.1155/2016/1879529]
   Mazzitelli M, 2025, MICROORGANISMS, V13, DOI 10.3390/microorganisms13010207
   Miele PS, 2002, AM J TRANSPLANT, V2, P678, DOI 10.1034/j.1600-6143.2002.20716.x
   Mun~oz P, 2002, CLIN INFECT DIS, V35, P896
   Paajanen J, 2019, MED MYCOL CASE REP, V24, P37, DOI 10.1016/j.mmcr.2019.03.003
   Pappas PG, 2013, CURR OPIN INFECT DIS, V26, P309
   Shoham S, 2012, FUTURE MICROBIOL, V7, P639, DOI [10.2217/FMB.12.28, 10.2217/fmb.12.28]
   Troke P, 2008, ANTIMICROB AGENTS CH, V52, P1743, DOI 10.1128/AAC.01388-07
   Xiao YP, 2024, ANN CLIN MICROB ANTI, V23, DOI 10.1186/s12941-024-00754-8
NR 19
TC 1
Z9 2
U1 1
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0732-8893
EI 1879-0070
J9 DIAGN MICR INFEC DIS
JI Diagn. Microbiol. Infect. Dis.
PD JUN
PY 2026
VL 115
IS 2
AR 117347
DI 10.1016/j.diagmicrobio.2026.117347
PG 4
WC Infectious Diseases; Microbiology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Microbiology
GA ES2WN
UT WOS:001708530700001
PM 41775156
OA hybrid
DA 2026-07-24
ER

PT J
AU von Rüden, C
   Wunder, J
   Schirdewahn, C
   Augat, P
   Hackl, S
AF von Rueden, Christian
   Wunder, Johannes
   Schirdewahn, Christoph
   Augat, Peter
   Hackl, Simon
TI Initial treatment of severe soft-tissue injuries in closed and open
   fractures to prevent fracture-related infection
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Article
DE Fracture; Soft tissue damage; Lesion; Fracture-related infection (FRI);
   Antibiotics; Negative pressure wound therapy (NPWT); Fracture fixation;
   Gustilo and Anderson classification
ID PRESSURE WOUND THERAPY; LOWER-LIMB FRACTURES; OPEN TIBIA FRACTURES;
   LOWER-EXTREMITY; SURGICAL DEBRIDEMENT; MANAGEMENT; TRAUMA; TIME;
   AMPUTATION; SALVAGE
AB The management of soft tissue damage during fracture treatment requires surgical proficiency and meticulous care adhering to established treatment protocols. This approach is paramount for minimizing the risk of potentially limb- or even life-threatening complications such as fracture-related infection (FRI) in all age groups. There is a general consensus on essential measures such as wound assessment, surgical debridement and early use of antibiotics. Treatment should always be based on the correct classification of the fracture and the corresponding soft tissue injury, but needs to be adapted to the individual patient considering general health status, secondary diagnoses and currently available treatment options.
C1 [von Rueden, Christian; Wunder, Johannes; Schirdewahn, Christoph] Klinikum Weiden, Dept Trauma Surg Orthopaed & Hand Surg, D-92637 Weiden, Germany.
   [von Rueden, Christian; Augat, Peter] Paracelsus Med Univ, Inst Biomech, Salzburg, Austria.
   [Augat, Peter] BG Unfallklin Murnau, Inst Biomech, Murnau, Germany.
   [Hackl, Simon] BG Unfallklin Murnau, Dept Trauma Surg, Murnau, Germany.
C3 Paracelsus Private Medical University
RP von Rüden, C (通讯作者)，Klinikum Weiden, Dept Trauma Surg Orthopaed & Hand Surg, D-92637 Weiden, Germany.
EM christian.vonrueden@kno.ag
RI ; Augat, Peter/A-2051-2011
OI von Rüden, Christian/0000-0001-6308-8378; Augat,
   Peter/0000-0003-4805-2128
FU Osteosynthesis and Trauma Care Foundation (OTCF); Stryker
FX This paper is part of a Supplement supported by the Osteosynthesis and
   Trauma Care Foundation (OTCF) through a research grant from Stryker.
CR Alt V, 2024, UNFALLCHIRURGIE, V127, P103, DOI 10.1007/s00113-023-01403-z
   Ashford RU, 2004, INJURY, V35, P411, DOI 10.1016/S0020-1383(03)00236-5
   Bärtl S, 2023, UNFALLCHIRURGIE, V126, P707, DOI 10.1007/s00113-022-01200-0
   Bosse MJ, 2001, J BONE JOINT SURG AM, V83A, P3, DOI 10.2106/00004623-200101000-00002
   Chan JKK, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD013555.pub2
   Chang YP, 2019, JBJS REV, V7, DOI 10.2106/JBJS.RVW.17.00197
   Costa ML, 2020, JAMA-J AM MED ASSOC, V323, P519, DOI 10.1001/jama.2020.0059
   Court-Brown CM, 1998, INJURY, V29, P529, DOI 10.1016/S0020-1383(98)00125-9
   Covey CDC, 2002, J BONE JOINT SURG AM, V84A, P1221, DOI 10.2106/00004623-200207000-00022
   Fodor L, 2012, INT J BURNS TRAUMA, V2, P51
   Foster AL, 2020, EXPERT REV ANTI-INFE, V18, P307, DOI 10.1080/14787210.2020.1729740
   Gäbel G, 2009, ZBL CHIR, V134, P292, DOI 10.1055/s-0029-1224526
   Grant-Freemantle MC, 2020, J ORTHOP TRAUMA, V34, P223, DOI 10.1097/BOT.0000000000001750
   GREGORY RT, 1985, J TRAUMA, V25, P1147, DOI 10.1097/00005373-198512000-00005
   Grisdela P, 2023, INJURY, V54, P722, DOI 10.1016/j.injury.2022.12.012
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Harley BJ, 2002, J ORTHOP TRAUMA, V16, P484, DOI 10.1097/00005131-200208000-00006
   Harry LE, 2009, PLAST RECONSTR SURG, V124, P1211, DOI 10.1097/PRS.0b013e3181b5a308
   Harwood PJ, 2006, J ORTHOP TRAUMA, V20, P181
   HOWE HR, 1987, AM SURGEON, V53, P205
   Iheozor-Ejiofor Z, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD012522.pub2
   Jaeger Martin, 2006, Injury, V37 Suppl 2, pS74, DOI 10.1016/j.injury.2006.04.012
   JOHANSEN K, 1990, J TRAUMA, V30, P568, DOI 10.1097/00005373-199005000-00007
   Jordan Daniel J, 2014, Open Orthop J, V8, P399, DOI 10.2174/1874325001408010399
   KINDSFATER K, 1995, J ORTHOP TRAUMA, V9, P121, DOI 10.1097/00005131-199504000-00006
   Lack WD, 2015, J ORTHOP TRAUMA, V29, P1, DOI [10.1097/bot.0000000000000262, 10.1097/BOT.0000000000000262, 10.1016/j.mporth.2014.12.008]
   Lee JJ, 2013, J BONE JOINT SURG AM, V95A, P850, DOI 10.2106/JBJS.L.00375
   Liu X, 2018, INT J SURG, V53, P72, DOI 10.1016/j.ijsu.2018.02.064
   Marais LC, 2023, ARCH ORTHOP TRAUM SU, DOI 10.1007/s00402-023-05073-9
   MCNAMARA MG, 1994, J ORTHOP TRAUMA, V8, P81, DOI 10.1097/00005131-199404000-00001
   Messner J, 2017, SURG INFECT, V18, P854, DOI 10.1089/sur.2017.108
   Morello V, 2023, EFORT OPEN REV, V8, P926, DOI 10.1530/EOR-23-0067
   Naique SB, 2006, J BONE JOINT SURG BR, V88B, P351, DOI 10.1302/0301-620X.88B3.17120
   Omar M, 2021, Open fractures Unfallchirurg, V124, P651, DOI [10.1007/s00113-021-01042-2, DOI 10.1007/S00113-021-01042-2]
   Pape HC, 2002, AM J SURG, V183, P622, DOI 10.1016/S0002-9610(02)00865-6
   Pfeifer R, 2016, CHIRURG, V87, P165, DOI 10.1007/s00104-015-0139-0
   Pollak AN, 2010, J BONE JOINT SURG AM, V92A, P7, DOI 10.2106/JBJS.H.00984
   Raj M, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.48848
   Roberts Craig S, 2005, Instr Course Lect, V54, P447
   Rupp M, 2023, Dtsch Arztebl Int., DOI [10.3238/arztebl.m2023.0233(Forthcoming):arztebl.m2023.0233, DOI 10.3238/ARZTEBL.M2023.0233(FORTHCOMING):ARZTEBL.M2023.0233]
   Rupp M, 2023, J BONE JOINT INFECT, V8, P165, DOI 10.5194/jbji-8-165-2023
   Rupp M, 2020, INJURY, V51, pS57, DOI 10.1016/j.injury.2019.10.074
   RUSSELL WL, 1991, ANN SURG, V213, P473, DOI 10.1097/00000658-199105000-00013
   Schenker ML, 2012, J BONE JOINT SURG AM, V94A, P1057, DOI 10.2106/JBJS.K.00582
   Schirò GR, 2015, BMC MUSCULOSKEL DIS, V16, DOI 10.1186/s12891-015-0832-7
   SCHLICKEWEI W, 1992, J BONE JOINT SURG BR, V74, P181, DOI 10.1302/0301-620X.74B2.1544948
   Shah A, 2021, BMJ QUAL SAF, V30, P559, DOI 10.1136/bmjqs-2020-011196
   Shanmuganathan R, 2008, INDIAN J ORTHOP, V42, P368, DOI 10.4103/0019-5413.43371
   Singh J, 2012, STRATEG TRAUMA LIMB, V7, P33, DOI 10.1007/s11751-012-0130-y
   Skaggs DL, 2005, J BONE JOINT SURG AM, V87A, P8, DOI 10.2106/JBJS.C.01561
   Spudil V, 2023, Rozhl Chir, V102, P315, DOI [10.33699/pis.2023.102.8.315-320, 10.33699/PIS.2023.102.8.315-320]
   Taeger G, 2005, J TRAUMA, V59, P408, DOI 10.1097/01.ta.0000175088.29170.3e
   TSCHERNE H, 1982, UNFALLHEILKUNDE, V85, P111
   Tu YK, 2008, INJURY, V39, pS3, DOI 10.1016/j.injury.2008.08.027
   Tuttle MS, 2009, J TRAUMA, V67, P602, DOI 10.1097/TA.0b013e3181aa21c0
   Ukay I, 2023, Swiss Medical Forum ‒ Schweizerisches Medizin-Forum, DOI [10.4414/smf.2023.09299, 10.4414/smf.2023.09299, DOI 10.4414/SMF.2023.09299]
   von Rüden C, 2008, EUR J TRAUMA EMERG S, V34, P582, DOI 10.1007/s00068-008-8007-y
   Webb LX, 2007, J BONE JOINT SURG AM, V89A, P923, DOI 10.2106/JBJS.F.00776
   Weitz-Marshall Amanda D, 2002, J Am Acad Orthop Surg, V10, P379
   White CB, 2003, CLIN ORTHOP RELAT R, P37, DOI 10.1097/01.blo.0000084402.53464.90
   Yang EC, 2003, CLIN ORTHOP RELAT R, P289, DOI 10.1097/01.blo.0000063795.32430.4c
   Yoneda H, 2024, INJURY, V55, DOI 10.1016/j.injury.2024.111447
   Zalavras Charalampos G, 2003, J Am Acad Orthop Surg, V11, P212
NR 64
TC 5
Z9 8
U1 1
U2 6
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 0020-1383
EI 1879-0267
J9 INJURY
JI Injury-Int. J. Care Inj.
PD NOV
PY 2024
VL 55
SU 6
AR 111935
DI 10.1016/j.injury.2024.111935
EA OCT 2024
PG 7
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA L1T7J
UT WOS:001348621600001
PM 39482034
DA 2026-07-24
ER

PT J
AU Searle, RJ
   Myers, D
AF Searle, R. J.
   Myers, D.
TI A survey of caesarean section surgical site infections with PICO™ Single
   Use Negative Pressure Wound Therapy System in high-risk patients in
   England and Ireland
SO JOURNAL OF HOSPITAL INFECTION
LA English
DT Article
DE Surgical site infections; Caesarean section; Obesity; Single-use
   negative pressure; wound therapy; Closed incisions
ID SURGERY
AB This article reports audit data from the introduction of the PICO (TM) System for caesarean section patients with high body mass index (BMI) in four hospitals in the UK and Ireland. PICO was used on closed surgical incisions following caesarean section in 399 patients with BMI >= 35 kg/m(2). Thirty-six out of 399 patients (9.0%) developed signs of surgical site infection (SSI), a rate lower than a previously reported incidence of 19.3% in a similar population. The readmission incidence was 0.8%. Therefore the use of PICO on closed surgical incisions may be associated with low incidence of SSI and readmission in this high-risk group. (C) 2017 Published by Elsevier Ltd on behalf of The Healthcare Infection Society.
C1 [Searle, R. J.; Myers, D.] Smith & Nephew Adv Wound Management, Kingston Upon Hull, N Humberside, England.
C3 Smith & Nephew
RP Searle, RJ (通讯作者)，Smith & Nephew, 101 Hessle Rd, Kingston Upon Hull HU3 2BN, N Humberside, England.
EM richard.searle@smith-nephew.com
FU Smith Nephew
FX This work was supported by Smith & Nephew.
CR Betrán AP, 2016, PLOS ONE, V11, DOI 10.1371/journal.pone.0148343
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   Health and Social Care Information Centre, 2015, NHS MAT STAT ENGL 20, P2013
   Health Survey for England, AD OB OV
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   National Institute for Health and Care Excellence, 2013, NICE SUPP COMM SURG
   NHS choices, CAES SECT
   Panda S, 2016, British Journal of Midwifery, V24, P322, DOI [10.12968/bjom.2016.24.5.322, 10.12968/bjom.2016.24.5.322, DOI 10.12968/BJOM.2016.24.5.322]
   Sebire NJ, 2001, INT J OBESITY, V25, P1175, DOI 10.1038/sj.ijo.0801670
   Wloch C, 2012, BJOG-INT J OBSTET GY, V119, P1324, DOI 10.1111/j.1471-0528.2012.03452.x
NR 10
TC 8
Z9 9
U1 0
U2 1
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 0195-6701
EI 1532-2939
J9 J HOSP INFECT
JI J. Hosp. Infect.
PD OCT
PY 2017
VL 97
IS 2
BP 122
EP 124
DI 10.1016/j.jhin.2017.02.023
PG 3
WC Public, Environmental & Occupational Health; Infectious Diseases
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Public, Environmental & Occupational Health; Infectious Diseases
GA FG6TC
UT WOS:000410522300003
PM 28807639
DA 2026-07-24
ER

PT J
AU Rasheed, H
   Diab, K
   Singh, T
   Chauhan, Y
   Haddad, P
   Zubair, MM
   Vowels, T
   Androas, E
   Rojo, M
   Auyang, P
   McFall, R
   Gomez, LF
   Mohamed, A
   Peden, E
   Rahimi, M
AF Rasheed, Haroon
   Diab, Kaled
   Singh, Tarundeep
   Chauhan, Yusuf
   Haddad, Paul
   Zubair, M. Mujeeb
   Vowels, Travis
   Androas, Edward
   Rojo, Manuel
   Auyang, Phillip
   McFall, Ross
   Gomez, Luis Felipe
   Mohamed, Ahmed
   Peden, Eric
   Rahimi, Maham
TI Contemporary Review to Reduce Groin Surgical Site Infections in Vascular
   Surgery
SO ANNALS OF VASCULAR SURGERY
LA English
DT Review
ID RESISTANT STAPHYLOCOCCUS-AUREUS; CONTAINING COLLAGEN IMPLANT; STERNAL
   WOUND INFECTIONS; FEMORAL-ARTERY ACCESS; CHLORHEXIDINE GLUCONATE; LOCAL
   APPLICATION; GRAFT INFECTIONS; MUSCLE FLAPS; RISK-FACTORS; ANTIMICROBIAL
   PROPHYLAXIS
AB Surgical site infection (SSIs) in lower extremity vascular procedures is a major contributor to patient morbidity and mortality. Despite previous advancements in preoperative and postoperative care, the surgical infection rate in vascular surgery remains high, particularly when groin incisions are involved. However, successfully targeting modifiable risk factors reduces the surgical site infection incidence in vascular surgery patients. We conducted an extensive literature review to evaluate the efficacy of various preventive strategies for groin surgical site infections. We discuss the role of preoperative showers, preoperative and postoperative antibiotics, collagen gentamicin implants, iodine impregnated drapes, types of skin incisions, negative pressure wound therapy, and prophylactic muscle flap transposition in preventing surgical site infection in the groin after vascular surgical procedures.
C1 [Rasheed, Haroon; Diab, Kaled; Singh, Tarundeep; Chauhan, Yusuf; Haddad, Paul; Zubair, M. Mujeeb; Vowels, Travis; Androas, Edward; Rojo, Manuel; Auyang, Phillip; McFall, Ross; Gomez, Luis Felipe; Mohamed, Ahmed; Peden, Eric; Rahimi, Maham] Houston Methodist Hosp, Methodist DeBakey Heart & Vasc Ctr, Houston, TX 77030 USA.
C3 Houston Methodist
RP Rahimi, M (通讯作者)，Houston Methodist Hosp, Dept Cardiovasc Surg, Smith Tower,6550 Fannin St,STE 1401, Houston, TX 77030 USA.
EM mrahimi@houstonmethodist.org
CR Aicher B, 2017, J VASC NURS, V35, P146, DOI 10.1016/j.jvn.2017.03.002
   ALEXANDER JW, 1985, ARCH SURG-CHICAGO, V120, P1357
   ALY R, 1988, AM J INFECT CONTROL, V16, P173, DOI 10.1016/0196-6553(88)90029-6
   Antonios VS, 2006, J INFECTION, V53, P49, DOI 10.1016/j.jinf.2005.10.004
   Antoniou GA, 2019, J VASC SURG, V70, P1700, DOI 10.1016/j.jvs.2019.01.083
   Argyriou C, 2017, J ENDOVASC THER, V24, P688, DOI 10.1177/1526602817722018
   Bandyk Dennis F, 2002, Semin Vasc Surg, V15, P268, DOI 10.1016/S0895-7967(02)70026-4
   BANDYK DF, 1984, ARCH SURG-CHICAGO, V119, P102
   Beirne C, 2008, VASCULAR, V16, P207, DOI 10.2310/6670.2008.00036
   Bejko J, 2015, J CARDIOVASC TRANSL, V8, P431, DOI 10.1007/s12265-015-9653-1
   Bratzler Dale W, 2013, Am J Health Syst Pharm, V70, P195, DOI [10.2146/ajhp120568, 10.1089/sur.2013.9999]
   Bratzler DW, 2005, AM J SURG, V189, P395, DOI 10.1016/j.amjsurg.2005.01.015
   Brehant O, 2013, INT J COLORECTAL DIS, V28, P119, DOI 10.1007/s00384-012-1557-9
   Brewer MB, 2015, AM SURGEON, V81, P1163
   BYRNE DJ, 1990, J HOSP INFECT, V15, P183, DOI 10.1016/0195-6701(90)90129-C
   Caiati JM, 2000, ANN VASC SURG, V14, P248, DOI 10.1007/s100169910042
   Canteras M, 2020, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD013153.pub2
   Casey AL, 2015, J ANTIMICROB CHEMOTH, V70, P2255, DOI 10.1093/jac/dkv100
   Cernohorsky P, 2011, J VASC SURG, V54, P327, DOI 10.1016/j.jvs.2010.12.067
   Chang WK, 2013, ANN SURG, V258, P59, DOI 10.1097/SLA.0b013e3182895b8c
   Chehab MA, 2018, J VASC INTERV RADIOL, V29, P1483, DOI 10.1016/j.jvir.2018.06.007
   CHESTER JF, 1983, ANN ROY COLL SURG, V65, P389
   CHESTER JF, 1992, ANN ROY COLL SURG, V74, P112
   Chlebicki MP, 2013, AM J INFECT CONTROL, V41, P167, DOI 10.1016/j.ajic.2012.02.014
   CLASSEN DC, 1992, NEW ENGL J MED, V326, P281, DOI 10.1056/NEJM199201303260501
   Cowie Scott E, 2005, Vasc Endovascular Surg, V39, P327, DOI 10.1177/153857440503900404
   Davis FM, 2017, J VASC SURG, V65, P1769, DOI 10.1016/j.jvs.2016.11.053
   DEWAN PA, 1987, AUST NZ J SURG, V57, P859, DOI 10.1111/j.1445-2197.1987.tb01281.x
   Diekema DJ, 2007, CLIN INFECT DIS, V44, P1101, DOI 10.1086/512820
   Earnshaw J J, 1989, Eur J Vasc Surg, V3, P323, DOI 10.1016/S0950-821X(89)80068-4
   Easterlin B, 2007, WOUNDS, V19, P331
   Edmiston CE Jr, 2015, JAMA SURG, V150, P1027, DOI 10.1001/jamasurg.2015.2210
   Eiselt D, 2009, ORTHOP NURS, V28, P141, DOI 10.1097/NOR.0b013e3181a469db
   Eklund AM, 2007, APMIS, V115, P1022, DOI 10.1111/j.1600-0463.2007.00836.x
   Engelhardt M, 2018, INT WOUND J, V15, P327, DOI 10.1111/iwj.12848
   Fischer JP, 2012, J VASC SURG, V55, P1081, DOI 10.1016/j.jvs.2011.10.110
   Fleischmann W, 1996, J HOSP INFECT, V34, P107, DOI 10.1016/S0195-6701(96)90135-8
   Fleming CA, 2018, J HOSP INFECT, V99, P75, DOI 10.1016/j.jhin.2017.10.022
   Frei E, 2011, VASC ENDOVASC SURG, V45, P688, DOI 10.1177/1538574411419528
   Friberg Ö, 2005, ANN THORAC SURG, V79, P153, DOI 10.1016/j.athoracsur.2004.06.043
   GARIBALDI RA, 1988, J HOSP INFECT, V11, P5, DOI 10.1016/0195-6701(88)90149-1
   Giles KA, 2010, ANN VASC SURG, V24, P48, DOI 10.1016/j.avsg.2009.05.003
   Goëau-Brissonnière O, 2011, ANN VASC SURG, V25, P134, DOI 10.1016/j.avsg.2010.09.002
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Graham RG, 2002, PLAST RECONSTR SURG, V109, P108, DOI 10.1097/00006534-200201000-00018
   Grelle Kelli, 2008, AORN J, V88, P261, DOI 10.1016/j.aorn.2008.03.006
   Gurusamy KS, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD010365.pub2
   Harbarth S, 2008, JAMA-J AM MED ASSOC, V299, P1149, DOI 10.1001/jama.299.10.1149
   Harris K A, 1992, J Vasc Nurs, V10, P13
   Hasselmann J, 2020, ANN SURG, V271, P48, DOI 10.1097/SLA.0000000000003364
   HAYEK LJ, 1987, J HOSP INFECT, V10, P165, DOI 10.1016/0195-6701(87)90143-5
   Hekman KE, 2019, J AM COLL SURGEONS, V228, P44, DOI 10.1016/j.jamcollsurg.2018.10.002
   Holdsworth J, 1999, ANN ROY COLL SURG, V81, P166
   HORCH R, 1989, VASA-J VASCULAR DIS, V18, P30
   Hussain ST, 2012, INT J SURG, V10, pS5, DOI 10.1016/j.ijsu.2012.05.015
   Illig KA, 2004, ANN VASC SURG, V18, P661, DOI 10.1007/s10016-004-0105-7
   Inui T, 2015, SEMIN VASC SURG, V28, P201, DOI 10.1053/j.semvascsurg.2016.02.002
   JOHNSON JA, 1988, ARCH SURG-CHICAGO, V123, P859
   Johnson JH, 1992, AORN J, V56, P347, DOI [10.1016/S0001-2092(07)68699-2, DOI 10.1016/S0001-2092(07)68699-2]
   Johnson MP, 2016, OBSTET GYNECOL, V127, P1135, DOI 10.1097/AOG.0000000000001449
   Kent RC, 1996, SURGERY, V119, P378
   Kiyooka T, 2007, CIRCULATION, V116, P173, DOI 10.1161/CIRCULATIONAHA.106.183095
   Koetje JH, 2015, SURG RES PRACT, V2015, P1
   Kramer A, 2010, GMS KRANKENHHYG INTE, P5
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   Lee E S, 2000, Surg Infect (Larchmt), V1, P257, DOI 10.1089/109629600750067183
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Lew W, 2011, SEMIN VASC SURG, V24, P211, DOI 10.1053/j.semvascsurg.2011.10.015
   Maeda K, 2015, J ENDOVASC THER, V22, P640, DOI 10.1177/1526602815591553
   Malde DJ, 2006, INT ANGIOL, V25, P204
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   MAY J, 1993, J HOSP INFECT, V24, P153, DOI 10.1016/0195-6701(93)90077-D
   McDonald M, 1998, AUST NZ J SURG, V68, P388, DOI 10.1111/j.1445-2197.1998.tb04785.x
   Mohammed S, 2013, J VASC SURG, V57, P1079, DOI 10.1016/j.jvs.2012.09.073
   MOORE WS, 1969, AM J SURG, V117, P342, DOI 10.1016/0002-9610(69)90368-7
   Morasch MD, 2004, J VASC SURG, V39, P1277, DOI 10.1016/j.jvs.2004.02.011
   Naylor AR, 2001, EUR J VASC ENDOVASC, V21, P289, DOI 10.1053/ejvs.2001.1311
   Nikulainen V, 2019, SURG INFECT, V20, P45, DOI 10.1089/sur.2018.202
   O'Connor S, 2006, J VASC SURG, V44, P38, DOI 10.1016/j.jvs.2006.02.053
   PANLILIO AL, 1992, INFECT CONT HOSP EP, V13, P582
   Parikh PP, 2018, ANN VASC SURG, V47, P143, DOI 10.1016/j.avsg.2017.08.019
   Patrick S, 2010, VASC ENDOVASC SURG, V44, P521, DOI 10.1177/1538574410373837
   PAULSON DS, 1993, AM J INFECT CONTROL, V21, P205, DOI 10.1016/0196-6553(93)90033-Z
   Almeida CEPC, 2014, INT J SURG, V12, P1100, DOI 10.1016/j.ijsu.2014.08.397
   Pesonen LO, 2018, ANN VASC SURG, V46, P127, DOI 10.1016/j.avsg.2017.07.009
   PITT HA, 1980, ANN SURG, V192, P356, DOI 10.1097/00000658-198009000-00011
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Ploeg AJ, 2009, AM J SURG, V197, P747, DOI 10.1016/j.amjsurg.2008.04.014
   Pounds LL, 2005, VASC ENDOVASC SURG, V39, pT1, DOI [DOI 10.1177/153857440503900608, 10.1177/153857440503900608]
   Raja SG, 2012, INT J SURG, V10, pS10, DOI 10.1016/j.ijsu.2012.05.018
   Raza Z, 1999, EUR J VASC ENDOVASC, V17, P5, DOI 10.1053/ejvs.1998.0651
   ROBBS JV, 1988, DRUGS, V35, P141, DOI 10.2165/00003495-198800352-00030
   ROBERTS JR, 1993, AM J SURG, V165, P341, DOI 10.1016/S0002-9610(05)80839-6
   Ruszczak Z, 2003, ADV DRUG DELIVER REV, V55, P1679, DOI 10.1016/j.addr.2003.08.007
   Rutten HJT, 1997, EUR J SURG, V163, P31
   SALZMANN G, 1983, THORAC CARDIOV SURG, V31, P239
   SCHWARTZ ME, 1988, J VASC SURG, V7, P802, DOI 10.1067/mva.1988.avs0070802
   Sexton F, 2020, INT J SURG, V76, P94, DOI 10.1016/j.ijsu.2020.02.037
   Siracuse JJ, 2013, J VASC SURG, V57, P700, DOI 10.1016/j.jvs.2012.09.049
   STANSBY G, 1994, BJS-BRIT J SURG, V81, P1119, DOI 10.1002/bjs.1800810812
   Stewart AH, 2007, J VASC SURG, V46, P148, DOI 10.1016/j.jvs.2007.02.065
   Stone PA, 2015, ANN SURG, V262, P495, DOI 10.1097/SLA.0000000000001433
   Svensson-Björk R, 2019, BJS-BRIT J SURG, V106, P310, DOI 10.1002/bjs.11100
   Swinnen J, 2010, ANN VASC SURG, V24, P336, DOI 10.1016/j.avsg.2009.07.020
   TOWNE JB, 1994, J VASC SURG, V19, P226, DOI 10.1016/S0741-5214(94)70098-2
   TYNDALL SH, 1994, J VASC SURG, V19, P858, DOI 10.1016/S0741-5214(94)70011-7
   Vogel TR, 2010, J VASC SURG, V51, P122, DOI 10.1016/j.jvs.2009.08.006
   Webster J, 2015, COCHRANE DATABASE SY, V2
   WENGROVITZ M, 1990, J VASC SURG, V11, P156, DOI 10.1067/mva.1990.16918
   WHITE JV, 1987, SURGERY, V102, P402
   Williams IM, 2003, EUR J VASC ENDOVASC, V25, P390, DOI 10.1053/ejvs.2002.1890
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Wilson WR, 2016, CIRCULATION, V134, pE412, DOI 10.1161/CIR.0000000000000457
   Wiseman JT, 2015, J VASC SURG, V62, P1023, DOI 10.1016/j.jvs.2015.04.453
   Wolcott R D, 2008, J Wound Care, V17, P333
   Yoshimura Y, 2003, WORLD J SURG, V27, P685, DOI 10.1007/s00268-003-6957-0
NR 117
TC 16
Z9 19
U1 0
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD APR
PY 2021
VL 72
BP 578
EP 588
DI 10.1016/j.avsg.2020.09.046
EA APR 2021
PG 11
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA RU0DW
UT WOS:000644823500005
PM 33157243
DA 2026-07-24
ER

PT J
AU Wang, HN
   Song, ZM
   Xia, DY
   Tang, Q
   Wu, L
   Yu, LL
   Sun, XL
AF Wang, Huining
   Song, Zumei
   Xia, Dongyun
   Tang, Qian
   Wu, Ling
   Yu, Lili
   Sun, Xiaoling
TI Multidisciplinary approach to squamous cell carcinoma originating in
   hidradenitis suppurativa lesions: a case report
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE hidradenitis suppurativa; inflammatory skin disease; multidisciplinary;
   negative pressure wound therapy; squamous cell carcinoma; wound; wound
   care; wound dressing; wound healing
AB Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease, and squamous cell carcinoma (SCC) is a rare complication of longstanding HS. In this case report, we describe the clinical management of a 30-year-old male patient with HS, with an eight-year history of a recurrent abscess and a nonhealing ulcer-like wound on his right buttock. The patient was also diagnosed with SCC originating from HS. A multidisciplinary team was established, comprising an oncologist, a plastic surgeon and two enterostomal therapists, to administer various treatments including chemotherapy, wound care, and surgical removal of lesions. The wound completely healed 201 days later, without any recurrence observed during follow-up. Declaration of interest: The authors have no conflicts of interest to declare.
C1 [Wang, Huining; Song, Zumei; Tang, Qian; Yu, Lili; Sun, Xiaoling] Nanjing Univ, Affiliated Hosp, Nanjing Drum Tower Hosp, Dept Jiangbei Outpatient,Med Sch, Nanjing, Jiangsu, Peoples R China.
   [Xia, Dongyun; Wu, Ling] Nanjing Univ, Nanjing Drum Tower Hosp, Wound Care Ctr, Affiliated Hosp,Med Sch, Nanjing, Jiangsu, Peoples R China.
C3 Nanjing University; Nanjing University
RP Sun, XL (通讯作者)，Nanjing Univ, Affiliated Hosp, Nanjing Drum Tower Hosp, Dept Jiangbei Outpatient,Med Sch, Nanjing, Jiangsu, Peoples R China.
EM sunxiaoling@nju.edu.cn
OI Wang, Huining/0009-0000-1500-9620
CR [Anonymous], 2017, Clin Cosmet Investig Dermatol, V10, P105, DOI [10.2147/CCID.S111019, DOI 10.2147/CCID.S111019]
   Canadian Skin Patient Alliance, 2020, Scarred for life: 2020 update: a national report of patients' experiences living with hidradenitis suppurativa
   Hurley H, 1989, Dermatologic Surgery
   Ingram JR, 2019, BRIT J DERMATOL, V180, P1009, DOI 10.1111/bjd.17537
   Johnston LA, 2022, J CUTAN MED SURG, V26, p2S, DOI 10.1177/12034754221116115
   Jourabchi N, 2017, INT WOUND J, V14, P435, DOI 10.1111/iwj.12671
   Kohorst JJ, 2019, DERMATOL SURG, V45, P519, DOI 10.1097/DSS.0000000000001713
   Lee JH, 2018, J EUR ACAD DERMATOL, V32, P1784, DOI 10.1111/jdv.15071
   Moloney S, 2022, J WOUND CARE, V31, P898, DOI 10.12968/jowc.2022.31.11.898
   Napolitano M, 2017, CLIN COSMET INV DERM, V10, P105, DOI 10.2147/CCID.S111019
   Sachdeva M, 2021, INT J DERMATOL, V60, pE459, DOI 10.1111/ijd.15677
   Schmults CD, 2021, J NATL COMPR CANC NE, V19, P1382, DOI 10.6004/jnccn.2021.0059
   Schultz GS, 2003, WOUND REPAIR REGEN, V11, pS1, DOI 10.1046/j.1524-475X.11.s2.1.x
   Thompson AM, 2021, BRIT J DERMATOL, V185, P225, DOI 10.1111/bjd.19926
NR 14
TC 0
Z9 0
U1 0
U2 1
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD MAR
PY 2025
VL 34
IS 3
BP 196
EP 199
DI 10.12968/jowc.2023.0200
PG 4
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA Z9H4H
UT WOS:001441927700005
PM 40047818
DA 2026-07-24
ER

PT J
AU Allen, P
   Pugh, J
   Blau, A
AF Allen, Pete
   Pugh, Jackson
   Blau, Alexander
TI Case Study: Acute Lumbar Paraspinal Compartment Syndrome in an Austere
   Military Environment
SO MILITARY MEDICINE
LA English
DT Article
AB The incidence of compartment syndrome of the lumbar paraspinal muscles is exceedingly rare. Approximately 24 hours following a high-intensity kettlebell swing workout, a 33-year-old Sailor presented to the medical department on board a forward deployed Wasp-class amphibious assault ship with increasing discomfort in his middle and lower back, and evidence of rhabdomyolysis. Discomfort quickly turned to unrelenting pain coupled with dorsal paresthesias and rigidity in the paraspinal muscles. He was taken emergently to the operating room, where his paraspinal muscles were released via fasciotomy. As a result of limited resources aboard the deployed ship, a negative pressure wound dressing was fashioned using the supplies available aboard the ship. Following 3 days of the negative pressure wound therapy, muscle bulging decreased substantially, and the skin was closed. After 4 weeks of physical therapy, he returned to full duty.
C1 [Allen, Pete; Pugh, Jackson; Blau, Alexander] US Fleet Forces Command, Dept Navy, Norfolk, VA 23551 USA.
RP Allen, P (通讯作者)，US Fleet Forces Command, Dept Navy, Norfolk, VA 23551 USA.
OI Blau, Alexander/0000-0002-6132-598X
CR Jaworski RL, 2015, MIL MED, V180, P179, DOI 10.7205/MILMED-D-14-00432
   Khan RJK, 2005, J BONE JOINT SURG AM, V87A, P1126, DOI 10.2106/JBJS.D.02133
   Kitajima I, 2002, AM J SPORT MED, V30, P283, DOI 10.1177/03635465020300022301
   Knox J, 2011, SPINE, V36, P1492, DOI 10.1097/BRS.0b013e3181f40ddd
   Nathan ST, 2012, INT ORTHOP, V36, P1221, DOI 10.1007/s00264-011-1386-4
   Paryavi E, 2010, SPINE, V35, pE1529, DOI 10.1097/BRS.0b013e3181ec4023
   Waterman BR, 2013, AM J SPORT MED, V41, P2545, DOI 10.1177/0363546513497922
NR 7
TC 1
Z9 3
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0026-4075
EI 1930-613X
J9 MIL MED
JI Milit. Med.
PD JAN-FEB
PY 2021
VL 186
IS 1-2
BP 254
EP 257
DI 10.1093/milmed/usaa382
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA SE1HS
UT WOS:000651826400055
PM 33128551
OA hybrid
DA 2026-07-24
ER

PT J
AU Li, JX
   Wu, CF
   Xu, C
AF Li, Jiaxin
   Wu, Caifeng
   Xu, Chao
TI Temporal Vascularized Fascial Flap Combined With Bilayer Artificial
   Dermis for Scalp Reconstruction With Calvarial Exposure: A
   Bioengineering Strategy Integrating Angiogenesis and Dermal Regeneration
SO JOURNAL OF CRANIOFACIAL SURGERY
LA English
DT Article
DE Artificial dermis; fascial flap; skull exposure; wound reconstruction
AB The reconstruction of traumatic scalp defects with skull exposure presents multifaceted challenges, including compromised vascular reconstruction, periosteal defects, and high aesthetic demands. This study reports the case of a 57-year-old female patient with a post-traumatic right temporal scalp defect and skull exposure after a traffic accident. A staged protocol involving negative pressure wound therapy, pedicled fascial flap transfer, and bilayer artificial dermis grafting achieved complete wound closure within 15 days. At the 8-month follow-up, the Vancouver Scar Scale score was 1, demonstrating optimal aesthetic and functional restoration. This approach synergizes the vascularization advantages of fascial flaps with the regenerative properties of artificial dermis, effectively addressing limitations of traditional methods-such as flap bulkiness and donor site morbidity-and offers a novel paradigm for skull exposure defect reconstruction.
C1 [Li, Jiaxin; Xu, Chao] Shandong Second Med Univ, Sch Clin Med, Weifang, Peoples R China.
   [Wu, Caifeng] Qingdao Univ, Affiliated Hosp, Dept Hand & Foot, Microsurg, Qingdao, Peoples R China.
   [Li, Jiaxin; Xu, Chao] Zibo Cent Hosp, Dept Plast Surg, Zibo, Peoples R China.
C3 Shandong Second Medical University; Qingdao University
RP Xu, C (通讯作者)，Zibo Cent Hosp, Zibo 250036, Shandong, Peoples R China.
EM leejiaxin01@foxmail.com; wucfsweet@163.com; chaoxu0021@126.com
CR Amirsadeghi A, 2020, BIOMATER SCI-UK, V8, P4073, DOI 10.1039/d0bm00266f
   Ehrenfeld M., 2023, Pedicled Flaps Oral and maxillofacial surgery: Surgical textbook and atlas, P641
   Hodea FV, 2025, LIFE-BASEL, V15, DOI 10.3390/life15010036
   Horoz U., 2024, J Craniofac Surg, V[Epub ahead of print].
   Horta R., 2025, J Craniofac Surg, V[Epub ahead of print].
   Innocenti A., 2021, Major scalp defect reconstruction with free flap: analysis of the results, V92
   Li YM, 2022, ACS APPL BIO MATER, V5, P20, DOI 10.1021/acsabm.1c00979
   Qiu XW, 2018, J PLAST SURG HAND SU, V52, P204, DOI 10.1080/2000656X.2017.1421547
   Tan JL, 2017, BURNS TRAUMA, V5, DOI 10.1186/s41038-017-0080-1
NR 9
TC 1
Z9 1
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1049-2275
EI 1536-3732
J9 J CRANIOFAC SURG
JI J. Craniofac. Surg.
PD OCT
PY 2025
VL 36
IS 7
BP e997
EP e999
DI 10.1097/SCS.0000000000011564
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 8JJ5B
UT WOS:001590070700006
PM 40587760
DA 2026-07-24
ER

PT J
AU Choi, K
   Cho, J
   Park, M
   Park, DH
   Lee, IJ
AF Choi, KyeongBeom
   Cho, JaeHo
   Park, MyongChul
   Park, Dong Ha
   Lee, Il Jae
TI Knee and Ankle Reconstruction With Reverse Anterolateral Thigh and Free
   Anterolateral Thigh Flap From One Donor Site
SO INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
LA English
DT Article; Proceedings Paper
CT 5th World Union of Wound-Healing-Societies (WUWHS)
CY SEP 25-29, 2016
CL Florence, ITALY
SP Wound Healing Soc
DE free tissue flaps; perforator flap; reconstructive surgical procedures;
   surgical flaps
ID PERFORATOR FLAP
AB Traditionally, the anterolateral thigh (ALT) free flap is used in distal lower extremity reconstruction. Reverse ALT flap has become one of the most popular choices for knee joint soft tissue defects. A 53-year-old man sustained a degloving injury in the right lateral side of the lower extremity from the lateral malleolar area to the knee joint area. The contamination was severe, necessitating serial debridement and negative pressure wound therapy. After 4 weeks, no more soft tissue necrosis was evident. No more microorganism growth was confirmed by swab culture. ALT free flap using proximal perforator was planned for lateral malleolar area reconstruction and reverse ALT flap using distal perforator was planned to cover knee joint after confirming the pedicle length was sufficient for simultaneous knee and lateral malleolar area reconstruction.
C1 [Choi, KyeongBeom; Park, MyongChul; Park, Dong Ha; Lee, Il Jae] Ajou Univ, Sch Med, Dept Plast & Reconstruct Surg, Worldcup Ro 164, Suwon 443721, Gyeonggi Do, South Korea.
   [Cho, JaeHo] Ajou Univ, Sch Med, Dept Orthoped Surg, Suwon, South Korea.
C3 Ajou University; Ajou University
RP Lee, IJ (通讯作者)，Ajou Univ, Sch Med, Dept Plast & Reconstruct Surg, Worldcup Ro 164, Suwon 443721, Gyeonggi Do, South Korea.
EM i00325@live.co.kr
CR Bibbo C, 2015, J ORTHOP TRAUMA, V29, P563, DOI 10.1097/BOT.0000000000000357
   Gravvanis A, 2009, ANN PLAS SURG, V62, P290, DOI 10.1097/SAP.0b013e31817d81fb
   Kang MJ, 2013, ARCH PLAST SURG-APS, V40, P575, DOI 10.5999/aps.2013.40.5.575
   Kim IK, 2012, ARCH PLAST SURG-APS, V39, P262
   Lorenzetti F, 2010, J PLAST RECONSTR AES, V63, P1523, DOI 10.1016/j.bjps.2009.08.003
   Pan SC, 2004, PLAST RECONSTR SURG, V114, P1768, DOI 10.1097/01.PRS.0000142416.91524.4C
   Sever C, 2012, INDIAN J PLAST SURG, V45, P478, DOI [10.4103/0970-0358.105939, 10.4103/0970-0358.105956]
   SONG YG, 1984, BRIT J PLAST SURG, V37, P149, DOI 10.1016/0007-1226(84)90002-X
   van der Zee CW, 2015, J FOOT ANKLE SURG, V54, P730, DOI 10.1053/j.jfas.2014.06.018
   Wong CH, 2013, ANN PLAS SURG, V70, P337, DOI 10.1097/SAP.0b013e318234e8e2
   Yamada S, 2014, J PLAST SURG HAND SU, V48, P197, DOI 10.3109/2000656X.2013.859146
   Zhang G, 1990, Zhonghua Yi Xue Za Zhi, V70, P676
NR 12
TC 2
Z9 2
U1 0
U2 2
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7346
EI 1552-6941
J9 INT J LOW EXTR WOUND
JI Int. J. Low. Extrem. Wounds
PD SEP
PY 2016
VL 15
IS 3
BP 267
EP 270
DI 10.1177/1534734616653210
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Dermatology; Surgery
GA DU9ZP
UT WOS:000382577100013
PM 27317019
DA 2026-07-24
ER

PT J
AU Ng, ZY
   Salgado, CJ
   Moran, SL
   Chim, H
AF Ng, Zhi Yang
   Salgado, Christopher J.
   Moran, Steven L.
   Chim, Harvey
TI Soft Tissue Coverage of the Mangled Upper Extremity
SO SEMINARS IN PLASTIC SURGERY
LA English
DT Article
DE upper extremity; hand; injury; soft tissue flap
ID ANTEROLATERAL THIGH FLAP; RECONSTRUCTION; TRAUMA; REPLANTATION;
   MANAGEMENT; AMPUTATION; SELECTION
AB Mangled upper extremity injuries usually involve high-impact trauma with crushing and tearing of the limb and its associated soft tissue structures. Such trauma is particularly mutilating because of the nature of the injury and the involvement of structures vital for proper function. Although advancements in flap technique and improvements in bone fixation methods have enabled good functional and clinical outcomes in limb salvage reconstruction, this remains a challenging area. Attempts at limb preservation should be fully exhausted before consideration is given for amputation, which results in significantly decreased function. Here the authors focus on the various modalities of soft tissue coverage available including allogenic substitutes, the adjunctive use of negative pressure wound therapy, and the design and utilization of flaps to address various defect configurations for the goals of wound healing, aesthetics, and functional restoration in the mangled upper extremity.
C1 [Ng, Zhi Yang] Alexandra Hosp, Dept Orthopaed Surg, Singapore, Singapore.
   [Salgado, Christopher J.; Chim, Harvey] Univ Miami, Miller Sch Med, Div Plast Surg, Miami, FL 33136 USA.
   [Moran, Steven L.] Mayo Clin, Div Plast Surg, Rochester, MN USA.
C3 University of Miami; Mayo Clinic
RP Chim, H (通讯作者)，Univ Miami, Miller Sch Med, Dept Surg, Div Plast Surg, Clin Res Bldg,1120 NW 14th St,4th Floor, Miami, FL 33136 USA.
EM harveychim@yahoo.com
RI Ng, Zhi Yang/N-8251-2018
OI Ng, Zhi Yang/0000-0003-0538-3066
CR Bastidas N, 2009, ANN PLAS SURG, V62, P410, DOI 10.1097/SAP.0b013e318184ab2f
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Brooks D, 2008, MICROSURG, V28, P606, DOI 10.1002/micr.20575
   Buntic RF, 2005, PLAST RECONSTR SURG, V116, P1434, DOI 10.1097/01.prs.0000182378.42555.be
   Chang J, 2001, MICROSURG, V21, P70, DOI 10.1002/micr.1012
   Chiou GJ, 2014, HAND CLIN, V30, P211, DOI 10.1016/j.hcl.2014.01.004
   Colen L, 2006, PLAST RECONSTR SURG, V117, P1323, DOI 10.1097/01.prs.0000204960.48050.e5
   Ellis CV, 2012, PLAST RECONSTR SURG, V130, p256S, DOI 10.1097/PRS.0b013e318265a5cf
   Fischer JP, 2013, J HAND SURG-AM, V38A, P2485, DOI 10.1016/j.jhsa.2013.03.041
   Fox P, 2014, ANN PLAS SURG, V72, pS9, DOI 10.1097/SAP.0000000000000146
   Friedrich JB, 2009, J HAND SURG-AM, V34A, P1148, DOI 10.1016/j.jhsa.2009.04.035
   GATTI JE, 1984, PLAST RECONSTR SURG, V73, P396, DOI 10.1097/00006534-198403000-00010
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Graham B, 1998, J HAND SURG-AM, V23A, P783, DOI 10.1016/S0363-5023(98)80151-2
   GREGORY RT, 1985, J TRAUMA, V25, P1147, DOI 10.1097/00005373-198512000-00005
   Harrison BL, 2013, PLAST RECONSTR SURG, V132, P591, DOI 10.1097/PRS.0b013e31829ad012
   HELFET DL, 1990, CLIN ORTHOP RELAT R, P80
   Kim EK, 2007, ANN PLAS SURG, V58, P536, DOI 10.1097/01.sap.0000245121.32831.47
   Kimata Y, 1998, PLAST RECONSTR SURG, V102, P1517, DOI 10.1097/00006534-199810000-00026
   LISTER G, 1988, J HAND SURG-AM, V13A, P22, DOI 10.1016/0363-5023(88)90193-1
   Mih AD, 1997, HAND CLIN, V13, P217
   Parrett BM, 2006, PLAST RECONSTR SURG, V117, P1315, DOI 10.1097/01.prs.0000204959.18136.36
   Parrett BM, 2010, PLAST RECONSTR SURG, V126, P1628, DOI 10.1097/PRS.0b013e3181ef8ea3
   PEACOCK K, 1987, CLIN ORTHOP RELAT R, P153
   Pederson WC, 2005, GREENS OPERATIVE HAN, P1648
   Peng F, 2013, MICROSURG, V33, P631, DOI 10.1002/micr.22170
   Russell R C., 2007, Clin Plast Surg, V34, pviii
   Russell RC, 2007, CLIN PLAST SURG, V34, P211, DOI 10.1016/j.cps.2006.12.003
   Sabapathy SR, 2014, HAND CLIN, V30, P185, DOI 10.1016/j.hcl.2014.01.002
   Sabino J, 2013, PLAST RECONSTR SURG, V132, p577E, DOI 10.1097/PRS.0b013e31829f4a08
   Saint-Cyr M, 2008, J RECONSTR MICROSURG, V24, P259, DOI 10.1055/s-2008-1078697
   Saint-Cyr M, 2007, HAND CLIN, V23, P37, DOI 10.1016/j.hcl.2007.02.007
   Slavin SA, 1997, PLAST RECONSTR SURG, V99, P742, DOI 10.1097/00006534-199703000-00021
   Slavin SA, 1997, PLAST RECONSTR SURG, V99, P730, DOI 10.1097/00006534-199703000-00020
   Tintle SM, 2010, J BONE JOINT SURG AM, V92A, P2934, DOI [10.2106/JBJS.J.00258, 10.2106/JBJSJ.00258]
   Togawa S, 2005, J BONE JOINT SURG BR, V87B, P1516, DOI 10.1302/0301-620X.87B11.16512
   Weigert R, 2011, J HAND SURG-EUR VOL, V36E, P185, DOI 10.1177/1753193410387329
   Woo SH, 2007, PLAST RECONSTR SURG, V119, P1823, DOI 10.1097/01.prs.0000259094.68803.3d
NR 38
TC 18
Z9 22
U1 0
U2 2
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 1535-2188
J9 SEMIN PLAST SURG
JI Semin. Plast. Surg.
PD FEB
PY 2015
VL 29
IS 1
BP 48
EP 54
DI 10.1055/s-0035-1544170
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA CQ4BG
UT WOS:000360548500008
PM 25685103
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Clements, JR
   Mierisch, C
   Bravo, CJ
AF Clements, J. Randolph
   Mierisch, Cay
   Bravo, Cesar J.
TI Management of Combined Soft Tissue and Osseous Defect of the Midfoot
   with a Free Osteocutaneous Radial Forearm Flap: A Case Report
SO JOURNAL OF FOOT & ANKLE SURGERY
LA English
DT Article
DE external fixation; foot; gunshot wound; open fracture; surgery
ID ONE-STAGE RECONSTRUCTION; FOOT
AB Extensive soft tissue and osseous defects of the foot are difficult to manage and often result in amputation. Most of these wounds are created by trauma, but other causes, such as infection and malignancy, can create similar defects. A variety of wound management options exist for the treatment of these challenging wounds, including negative pressure wound therapy, autogenous skin grafting, and the use of skin substitutes, as well as internal and external fixation methods. In the present report, we describe the use of a free osteocutaneous radial forearm flap to manage a 10-cm x 5-cm dorsal soft tissue defect and a 2.5-cm second metatarsal diaphyseal defect in an adult male. (C) 2012 by the American College of Foot and Ankle Surgeons. All rights reserved.
C1 [Clements, J. Randolph] Virginia Tech Carilion Sch Med, Carilion Clin, Roanoke, VA 24014 USA.
   [Mierisch, Cay; Bravo, Cesar J.] Carilion Clin, Upper Extrem & Microvasc Surg Serv, Roanoke, VA USA.
RP Clements, JR (通讯作者)，Virginia Tech Carilion Sch Med, Carilion Clin, 3 Riverside Circle, Roanoke, VA 24014 USA.
EM jrclements@carilionclinic.org
RI Bravo, Cesar/ABB-3569-2020
OI Bravo, Cesar/0000-0002-3641-1368
CR Banerjee R, 2010, J FOOT ANKLE SURG, V49, P301, DOI 10.1053/j.jfas.2010.02.011
   Bowers KW, 2000, J BONE JOINT SURG AM, V82A, P694, DOI 10.2106/00004623-200005000-00010
   Keeling JJ, 2010, FOOT ANKLE CLIN, V15, P139, DOI 10.1016/j.fcl.2009.10.003
   Lykoudis EG, 2010, MICROSURG, V30, P64, DOI 10.1002/micr.20687
   Serletti J M, 2001, Foot Ankle Clin, V6, P839, DOI 10.1016/S1083-7515(02)00007-4
   Shawen SB, 2010, FOOT ANKLE CLIN, V15, P63, DOI 10.1016/j.fcl.2009.11.005
   SWANSON E, 1990, PLAST RECONSTR SURG, V85, P258, DOI 10.1097/00006534-199002000-00016
   Tan O, 2008, J RECONSTR MICROSURG, V24, P53, DOI 10.1055/s-2008-1064924
   Yazar S, 2004, PLAST RECONSTR SURG, V114, P1457, DOI 10.1097/01.PRS.0000138811.88807.65
NR 9
TC 11
Z9 14
U1 0
U2 4
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1067-2516
J9 J FOOT ANKLE SURG
JI J. Foot Ankle Surg.
PD JAN-FEB
PY 2012
VL 51
IS 1
BP 118
EP 122
DI 10.1053/j.jfas.2011.10.022
PG 5
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 866HU
UT WOS:000298372100027
PM 22083066
DA 2026-07-24
ER

PT J
AU Kline, BP
   Jeganathan, NA
AF Kline, Bryan P.
   Jeganathan, Nimalan A.
TI Necrotizing Soft Tissue Infections of the Perineum
SO CLINICS IN COLON AND RECTAL SURGERY
LA English
DT Article
DE necrotizing soft tissue infection; Fournier's gangrene; surgical
   debridement
ID STOMA SITE MARKING; FOURNIERS GANGRENE; HYPERBARIC-OXYGEN; FASCIITIS;
   MANAGEMENT; MORTALITY; OUTCOMES; DETERMINANTS; MULTICENTER; DIAGNOSIS
AB Necrotizing soft tissue infections of the perineum are rapidly progressing infections associated with significant morbidity and mortality. Prompt diagnosis and management with early surgical debridement is necessary to improve survival from this deadly disease. Repeat debridements are not uncommon. Important adjuncts to surgery include broad-spectrum antibiotics and management in an intensive care unit, as patients frequently develop multisystem organ failure. Once the acute phase is managed, fecal diversion with either an ostomy or fecal management catheter can be considered to decrease soiling of the wound and facilitate healing. Long-term management requires meticulous wound care, often with the assistance of negative pressure wound therapy. Patients may ultimately require skin grafts or tissue flaps for soft tissue coverage following extensive surgical debridements.
C1 [Kline, Bryan P.] Penn State Univ, Coll Med, Dept Surg, Hershey, PA 17033 USA.
   [Jeganathan, Nimalan A.] Penn State Univ, Coll Med, Dept Surg, Div Colon & Rectal Surg, 500 Univ Dr, Hershey, PA 17033 USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE);
   Pennsylvania State University; Penn State Health; Pennsylvania
   Commonwealth System of Higher Education (PCSHE); Pennsylvania State
   University; Penn State Health
RP Jeganathan, NA (通讯作者)，Penn State Univ, Coll Med, Dept Surg, Div Colon & Rectal Surg, 500 Univ Dr, Hershey, PA 17033 USA.
EM njeganathan@pennstatehealth.psu.edu
FU Marshia and Peter Carlino Early Career Professorship at Penn State
   Hershey Medical Center
FX This work was supported by the Marshia and Peter Carlino Early Career
   Professorship at Penn State Hershey Medical Center.
CR Andreasen TJ, 2001, PLAST RECONSTR SURG, V107, P1025, DOI 10.1097/00006534-200104010-00019
   Baykara ZG, 2014, OSTOMY WOUND MANAG, V60, P16
   Bilton BD, 1998, AM SURGEON, V64, P397
   Bonne SL, 2017, INFECT DIS CLIN N AM, V31, P497, DOI 10.1016/j.idc.2017.05.011
   Bronder C S, 2004, Colorectal Dis, V6, P518, DOI 10.1111/j.1463-1318.2004.00663.x
   Brown CVR, 2018, J TRAUMA ACUTE CARE, V84, P225, DOI 10.1097/TA.0000000000001739
   Bryant AE, 2005, J INFECT DIS, V192, P1014, DOI 10.1086/432729
   Cainzos M, 2007, CURR OPIN CRIT CARE, V13, P433, DOI 10.1097/MCC.0b013e32825a6a1b
   Chen SY, 2010, ANN PLAS SURG, V64, P765, DOI 10.1097/SAP.0b013e3181ba5485
   Devaney B, 2015, ANAESTH INTENS CARE, V43, P685, DOI 10.1177/0310057X1504300604
   Elliott DC, 1996, ANN SURG, V224, P672, DOI 10.1097/00000658-199611000-00011
   Eray IC, 2015, INDIAN J SURG, V77, pS438, DOI 10.1007/s12262-013-0868-6
   Erol B, 2010, UROLOGY, V75, P1193, DOI 10.1016/j.urology.2009.08.090
   Eskes A, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008059.pub3
   Faraklas I, 2016, SURG INFECT, V17, P773, DOI 10.1089/sur.2015.238
   Fernando SM, 2019, ANN SURG, V269, P58, DOI [10.1097/sla.0000000000002774, 10.1097/SLA.0000000000002774]
   Fitzmaurice M, 2006, J PLAST RECONSTR AES, V59, P1249, DOI 10.1016/j.bjps.2006.02.009
   Fournier JA., 1883, GANGRENE FOUDROYANTE, V4, P589
   Glasgow SC, 2012, DIS COLON RECTUM, V55, P482, DOI 10.1097/DCR.0b013e3182468c22
   Hayeri MR, 2016, RADIOGRAPHICS, V36, P1888, DOI 10.1148/rg.2016160068
   Hietbrink F, 2016, WORLD J EMERG SURG, V11, DOI 10.1186/s13017-016-0108-z
   Hsiao CT, 2020, PLOS ONE, V15, DOI 10.1371/journal.pone.0227748
   Inglin RA, 2015, INT J COLORECTAL DIS, V30, P293, DOI 10.1007/s00384-014-2065-x
   Jones J., 1871, Surgical memoirs of the war of rebellion
   Kabay S, 2008, INT UROL NEPHROL, V40, P997, DOI 10.1007/s11255-008-9401-4
   Kihiczak GG, 2006, J EUR ACAD DERMATOL, V20, P365, DOI 10.1111/J.1468-3083.2006.01487.x
   Klink CD, 2011, INT J COLORECTAL DIS, V26, P431, DOI 10.1007/s00384-010-1123-2
   Korkut M, 2003, DIS COLON RECTUM, V46, P649, DOI 10.1007/s10350-004-6626-x
   LAOR E, 1995, J UROLOGY, V154, P89, DOI 10.1016/S0022-5347(01)67236-7
   Lauerman MH, 2017, J TRAUMA ACUTE CARE, V83, P443, DOI [10.1097/TA.0000000000001562, 10.1097/ta.0000000000001562]
   Lee TC, 2007, AM J SURG, V194, P809, DOI 10.1016/j.amjsurg.2007.08.047
   Levett D, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD007937.pub2
   Levy MM, 2018, CRIT CARE MED, V46, P997, DOI 10.1097/CCM.0000000000003119
   Linnér A, 2014, CLIN INFECT DIS, V59, P851, DOI 10.1093/cid/ciu449
   Mallikarjuna M N, 2012, ISRN Surg, V2012, P942437, DOI 10.5402/2012/942437
   Maltezou HC, 2006, INT J ANTIMICROB AG, V27, P87, DOI 10.1016/j.ijantimicag.2005.11.004
   MCHENRY CR, 1995, ANN SURG, V221, P558, DOI 10.1097/00000658-199505000-00013
   Nelson GE, 2016, CLIN INFECT DIS, V63, P478, DOI 10.1093/cid/ciw248
   Nylund G, 1997, EUR J SURG, V163, P627
   Person B, 2012, DIS COLON RECTUM, V55, P783, DOI 10.1097/DCR.0b013e31825763f0
   RISEMAN JA, 1990, SURGERY, V108, P847
   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
   Sartelli M, 2014, WORLD J EMERG SURG, V9, DOI 10.1186/1749-7922-9-57
   Shiroff AM, 2014, J INTENSIVE CARE MED, V29, P138, DOI 10.1177/0885066612463680
   Silberstein Jonathan, 2008, Rev Urol, V10, P76
   Stevens DL, 2014, CLIN INFECT DIS, V59, P147, DOI [10.1093/cid/ciu444, 10.1093/cid/ciu296]
   STEVENS DL, 1995, CLIN INFECT DIS, V20, pS154, DOI 10.1093/clinids/20.Supplement_2.S154
   Tang LM, 2015, SPRINGERPLUS, V4, DOI 10.1186/s40064-014-0783-8
   Uchino H, 2020, INJURY, V51, P1238, DOI 10.1016/j.injury.2020.02.121
   Wong CH, 2004, CRIT CARE MED, V32, P1535, DOI 10.1097/01.CCM.0000129486.35458.7D
   Wong CH, 2003, J BONE JOINT SURG AM, V85A, P1454, DOI 10.2106/00004623-200308000-00005
NR 51
TC 2
Z9 4
U1 1
U2 5
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 1531-0043
EI 1530-9681
J9 CLIN COLON RECT SURG
JI Clin. Colon Rectal Surg.
PD MAY
PY 2022
VL 35
IS 03
BP 237
EP 243
DI 10.1055/s-0041-1740102
EA FEB 2022
PG 7
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 3S5TD
UT WOS:000753152000001
PM 35966380
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Wang, HC
   Wang, YT
   Long, X
   Wang, XJ
AF Wang, Hayson Chenyu
   Wang, Yunting
   Long, Xiao
   Wang, Xiaojun
TI Mandibular osteomyelitis after hyaluronic acid injection
SO JOURNAL OF COSMETIC DERMATOLOGY
LA English
DT Article
DE hyaluronic acid; infection; mandibular osteomyelitis
ID MANAGEMENT
AB Background Mandibular osteomyelitis after filler injection is extremely rare. Aims We reported a case of mandibular osteomyelitis after hyaluronic acid injection. Patients A 33-year-old woman received 1 mL hyaluronic acid injection on her chin 1 year ago, after which her chin kept swelling and painful, and gradually ulcerated with pus flowing out. She received antibiotics, debridement procedures, negative pressure wound therapy, and hyperbaric oxygen therapy without symptoms improved. Cone-beam computed tomography scan showed local bone destruction, sequestrum formation, and tissue calcification on the right mandible body. The patient was diagnosed with mandibular osteomyelitis and received local curettage for the removal of necrotized bone. Results Literature search found no case reports on mandibular osteomyelitis after filler injection so far. Conclusion Minimizing the risk of contamination and infection is strictly required during the filler injection process. Once the patient shows signs of incurable mandibular infection postoperation, clinicians should consider the possibility of osteomyelitis.
C1 [Wang, Hayson Chenyu; Long, Xiao; Wang, Xiaojun] Peking Union Med Coll & Chinese Acad Med Sci, Dept Plast Surg, Peking Union Med Coll Hosp, Beijing, Peoples R China.
   [Wang, Hayson Chenyu] Univ Oxford, Nuffield Dept Surg Sci, Oxford, England.
   [Wang, Yunting] Peking Union Med Coll & Chinese Acad Med Sci, Dept Stomatol, Peking Union Med Coll Hosp, Beijing, Peoples R China.
C3 Chinese Academy of Medical Sciences - Peking Union Medical College;
   Peking Union Medical College Hospital; Peking Union Medical College;
   University of Oxford; Chinese Academy of Medical Sciences - Peking Union
   Medical College; Peking Union Medical College; Peking Union Medical
   College Hospital
RP Wang, XJ (通讯作者)，Peking Union Med Coll & Chinese Acad Med Sci, Dept Plast Surg, Peking Union Med Coll Hosp, Beijing, Peoples R China.
EM pumchwxj@163.com
RI wang, xiaojun/NFT-0476-2025; Wang, Chenyu/AAN-8560-2020
OI Wang, Chenyu/0000-0002-2958-1588
CR Anehosur V, 2019, J ORAL MAXIL SURG, V77, P2285, DOI 10.1016/j.joms.2019.06.187
   Artzi O, 2016, DERMATOL SURG, V42, P31, DOI 10.1097/DSS.0000000000000562
   Baltensperger M, 2004, J CRANIO MAXILL SURG, V32, P43, DOI 10.1016/j.jcms.2003.07.008
   Baur DA, 2015, J ORAL MAXIL SURG, V73, P655, DOI 10.1016/j.joms.2014.10.017
   Bevin CR, 2008, J ORAL MAXIL SURG, V66, P2073, DOI 10.1016/j.joms.2008.06.029
   Carbonell AM, 2005, SURG ENDOSC, V19, P430, DOI 10.1007/s00464-004-8810-4
   Cassuto D, 2013, PLAST RECONSTR SURG, V132, p48S, DOI 10.1097/PRS.0b013e31829e52a7
   Del Campo R, 2015, DERMATOL SURG, V41, P940, DOI 10.1097/DSS.0000000000000419
   Farahani SS, 2012, HEAD NECK PATHOL, V6, P16, DOI 10.1007/s12105-011-0304-9
   Goodman GJ, 2020, AUSTRALAS J DERMATOL, V61, P217, DOI 10.1111/ajd.13273
   Lee JM, 2015, ARCH PLAST SURG-APS, V42, P232, DOI 10.5999/aps.2015.42.2.232
   Marschall JS, 2019, J ORAL MAXIL SURG, V77, P1490, DOI 10.1016/j.joms.2019.01.036
   Marusza W, 2019, INFECT DRUG RESIST, V12, P469, DOI 10.2147/IDR.S186996
   Re K, 2019, MED GAS RES, V9, P93, DOI 10.4103/2045-9912.260651
   Saint Amanda MJ, 2017, J STOMATOL ORAL MAXI, V118, P342, DOI 10.1016/j.jormas.2017.08.006
   Shin Jongweon, 2019, Arch Craniofac Surg, V20, P270, DOI [10.7181/acfs.2019.00311, 10.7181/acfs.2019.00311]
   Trobos M, 2018, CLIN IMPLANT DENT R, V20, P738, DOI 10.1111/cid.12629
   Wilson MJV, 2018, DERMATOL SURG, V44, P985, DOI 10.1097/DSS.0000000000001461
NR 18
TC 4
Z9 4
U1 0
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1473-2130
EI 1473-2165
J9 J COSMET DERMATOL-US
JI J. Cosmet. Dermatol.
PD FEB
PY 2021
VL 20
IS 2
BP 457
EP 459
DI 10.1111/jocd.13575
EA JUL 2020
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA PS6MT
UT WOS:000548122100001
PM 32592232
DA 2026-07-24
ER

PT J
AU Liu, X
   Zhao, P
   Wu, XZ
   Zhao, YW
   Zhou, FF
   Luo, Y
   Jia, XL
   Zhong, W
   Xing, M
   Lyu, G
AF Liu, Xing
   Zhao, Peng
   Wu, Xiaozhuo
   Zhao, Yawei
   Zhou, Feifan
   Luo, Ying
   Jia, Xiaoli
   Zhong, Wen
   Xing, Malcolm
   Lyu, Guozhong
TI Negative Pressure Smart Patch to Sense and Heal the Wound
SO ADVANCED SCIENCE
LA English
DT Article
DE drug delivery; glucose-sensing; microspheres; pH-sensing; wound
   monitoring
ID PH VALUE; THERAPY; INFECTION; REPAIR; MECHANISM; DRESSINGS; HYDROGEL;
   IMPACT
AB Negative pressure wound therapy (NPWT) offers significant advantages in terms of rate and time for healing through generating sub-vacuum to draw out inflammatory exudate and promote wound closure. However, continuous drainage probably leads to healing delay due to the lack of information about the real status of the wound bed and the potential risk of infection. To address this concern, printed Negative Pressure Smart Patch (NPSP) is reported by integrating smart real-time sensing acidity (infection) and glucose, and anti-infection into NPWT systems. In addition, NPSP delivers vancomycin through chitosan porous microspheres under negative pressure to modulate wound healing. Compared with NPWT, NPSP projects a promising approach to removing bacteria, reducing local inflammation, and accelerating healing in a short period of time.
C1 [Liu, Xing; Zhao, Peng; Zhou, Feifan; Luo, Ying; Jia, Xiaoli; Lyu, Guozhong] Jiangnan Univ, Affiliated Hosp, Engn Res Ctr, Minist Educ Wound Repair Technol, Wuxi 214000, Peoples R China.
   [Liu, Xing; Zhou, Feifan; Luo, Ying; Jia, Xiaoli; Lyu, Guozhong] Jiangnan Univ, Wuxi Sch Med, Wuxi 214000, Peoples R China.
   [Wu, Xiaozhuo; Xing, Malcolm] UNIV MANITOBA, DEPT MECH ENGN, WINNIPEG, MB R3T 2N2, Canada.
   [Zhao, Yawei; Zhong, Wen] Univ Manitoba, Dept Biosyst Engn, Winnipeg, MB R3T 2N2, Canada.
C3 Jiangnan University; Jiangnan University; University of Manitoba;
   University of Manitoba
RP Lyu, G (通讯作者)，Jiangnan Univ, Affiliated Hosp, Engn Res Ctr, Minist Educ Wound Repair Technol, Wuxi 214000, Peoples R China.; Lyu, G (通讯作者)，Jiangnan Univ, Wuxi Sch Med, Wuxi 214000, Peoples R China.; Xing, M (通讯作者)，UNIV MANITOBA, DEPT MECH ENGN, WINNIPEG, MB R3T 2N2, Canada.
EM malcolm.xing@umanitoba.ca; luguozhong@jiangnan.edu.cn
RI Jia, Xiaoli/OZE-4908-2025; Wu, Xiaozhuo/ODM-7515-2025; Zhou,
   Feifan/C-6861-2013
OI xing, malcolm/0000-0002-3547-0462; 刘, 星/0009-0009-2475-9736; Zhao,
   Peng/0009-0001-0684-6088
CR Adeel M, 2021, ADV FUNCT MATER, V31, DOI 10.1002/adfm.202106023
   Al-Ahmary KM, 2024, INT J BIOL MACROMOL, V268, DOI 10.1016/j.ijbiomac.2024.131493
   Beduk T, 2022, BIOSENSORS-BASEL, V12, DOI 10.3390/bios12080583
   Brown MS, 2018, FRONT BIOENG BIOTECH, V6, DOI 10.3389/fbioe.2018.00047
   Cai D, 2021, MATER TODAY BIO, V12, DOI 10.1016/j.mtbio.2021.100127
   Dargaville TR, 2013, BIOSENS BIOELECTRON, V41, P30, DOI 10.1016/j.bios.2012.09.029
   de Oliveira S, 2016, NAT REV IMMUNOL, V16, P378, DOI 10.1038/nri.2016.49
   Dizon JRC, 2018, ADDIT MANUF, V20, P44, DOI 10.1016/j.addma.2017.12.002
   Dong RN, 2021, NANO TODAY, V41, DOI 10.1016/j.nantod.2021.101290
   Edmonds M, 2006, DRUGS, V66, P913, DOI 10.2165/00003495-200666070-00003
   Ferris M, 2024, NAT COMMUN, V15, DOI 10.1038/s41467-024-47073-2
   Frykberg RG, 2015, ADV WOUND CARE, V4, P560, DOI 10.1089/wound.2015.0635
   Gamerith C, 2019, SENSOR ACTUAT B-CHEM, V301, DOI 10.1016/j.snb.2019.126966
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Gurtner GC, 2008, NATURE, V453, P314, DOI 10.1038/nature07039
   Hasan MY, 2015, DIABET FOOT ANKLE, V6, DOI 10.3402/dfa.v6.27618
   Hoque J, 2018, BIOMACROMOLECULES, V19, P267, DOI 10.1021/acs.biomac.7b00979
   Horta-Velázquez A, 2024, INT J BIOL MACROMOL, V254, DOI 10.1016/j.ijbiomac.2023.127737
   Ikushima AJ, 2000, J APPL PHYS, V88, P1201, DOI 10.1063/1.373805
   Jankowska DA, 2017, BIOSENS BIOELECTRON, V87, P312, DOI 10.1016/j.bios.2016.08.072
   Ji SZ, 2021, BURNS TRAUMA, V9, DOI 10.1093/burnst/tkab018
   Jia XL, 2023, BIOACT MATER, V26, P142, DOI 10.1016/j.bioactmat.2023.02.017
   Kamolz LP, 2004, BURNS, V30, P253, DOI 10.1016/j.burns.2003.12.003
   Kar A, 2022, BIOMATERIALS, V283, DOI 10.1016/j.biomaterials.2022.121435
   Keenan C, 2025, ADV WOUND CARE, V14, P33, DOI 10.1089/wound.2023.0157
   Kuo SH, 2020, DIAGNOSTICS, V10, DOI 10.3390/diagnostics10020107
   Lee DU, 2023, BIOMATER RES, V27, DOI 10.1186/s40824-023-00355-0
   Li ZR, 2019, INT WOUND J, V16, P1214, DOI 10.1111/iwj.13197
   Lipsky BA, 2006, PLAST RECONSTR SURG, V117, p212S, DOI 10.1097/01.prs.0000222737.09322.77
   Lipsky BA, 2012, CLIN INFECT DIS, V54, P1679, DOI [10.1093/cid/cis460, 10.1093/cid/cis346]
   Liu L, 2017, POLYMERS-BASEL, V9, DOI [10.7939/r3ns0mb70, 10.3390/polym9110558]
   Luo RZ, 2023, ADV MATER, V35, DOI 10.1002/adma.202208395
   Ma H, 2024, ACTA BIOMATER, V187, P183, DOI 10.1016/j.actbio.2024.08.048
   Manikkath J, 2021, ADV DRUG DELIVER REV, V179, DOI 10.1016/j.addr.2021.113997
   Martin P, 1997, SCIENCE, V276, P75, DOI 10.1126/science.276.5309.75
   Mirani B, 2023, ADV HEALTHC MATER, V12, DOI 10.1002/adhm.202203233
   Miyanaga A, 2023, NURS OPEN, V10, P1415, DOI 10.1002/nop2.1392
   Mori K, 2023, J CONTROL RELEASE, V355, P1, DOI 10.1016/j.jconrel.2023.01.046
   Murphy SV, 2014, NAT BIOTECHNOL, V32, P773, DOI 10.1038/nbt.2958
   Normandin S, 2021, SEMIN PLAST SURG, V35, P164, DOI 10.1055/s-0041-1731792
   Ono S, 2015, BURNS, V41, P820, DOI 10.1016/j.burns.2014.10.023
   Panzarasa G, 2017, SENSOR ACTUAT B-CHEM, V249, P156, DOI 10.1016/j.snb.2017.04.045
   Pasaribu KM, 2024, INT J BIOL MACROMOL, V279, DOI 10.1016/j.ijbiomac.2024.135602
   Percival SL, 2014, WOUND REPAIR REGEN, V22, P174, DOI 10.1111/wrr.12125
   Qu Z, 2024, MATER TODAY BIO, V26, DOI 10.1016/j.mtbio.2024.101093
   Rahimi R, 2017, ACS APPL MATER INTER, V9, P9015, DOI 10.1021/acsami.6b16228
   Rahmanian-Schwarz A, 2012, BURNS, V38, P573, DOI 10.1016/j.burns.2011.10.010
   Rengier F, 2010, INT J COMPUT ASS RAD, V5, P335, DOI 10.1007/s11548-010-0476-x
   Rodrigues M, 2019, PHYSIOL REV, V99, P665, DOI 10.1152/physrev.00067.2017
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Schintler MV, 2012, DIABETES-METAB RES, V28, P72, DOI 10.1002/dmrr.2243
   Schneider LA, 2007, ARCH DERMATOL RES, V298, P413, DOI 10.1007/s00403-006-0713-x
   Schreml S, 2010, J EUR ACAD DERMATOL, V24, P373, DOI 10.1111/j.1468-3083.2009.03413.x
   Shi L, 2011, J WOUND OSTOMY CONT, V38, P514, DOI 10.1097/WON.0b013e31822ad034
   Strecker-McGraw MK, 2007, EMERG MED CLIN N AM, V25, P1, DOI 10.1016/j.emc.2006.12.002
   Tan MH, 2022, ADV MATER, V34, DOI 10.1002/adma.202108491
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   Vig S, 2011, J TISSUE VIABILITY, V20, pS1, DOI 10.1016/j.jtv.2011.07.002
   Vikatmaa P, 2008, EUR J VASC ENDOVASC, V36, P438, DOI 10.1016/j.ejvs.2008.06.010
   Wall C, 2023, NPJ DIGIT MED, V6, DOI 10.1038/s41746-023-00971-z
   Wang CR, 2022, ADV FUNCT MATER, V32, DOI 10.1002/adfm.202111022
   Wang L., 2023, INT J BIOL MACROMOL, V258
   Watters C, 2015, CHRONIC WOUND CARE M, V2, P53, DOI 10.2147/CWCMR.S60317
   Yang P, 2019, SMALL, V15, DOI 10.1002/smll.201902823
   Yang YX, 2024, ACS NANO, V18, P24705, DOI 10.1021/acsnano.4c08258
   Zhang XY, 2024, ADV COLLOID INTERFAC, V332, DOI 10.1016/j.cis.2024.103267
   Zhang XM, 2022, ACS APPL MATER INTER, V14, P12984, DOI 10.1021/acsami.1c22629
   Zhang Y, 2017, FRONT PHARMACOL, V8, DOI 10.3389/fphar.2017.00784
   Zhao J, 2018, J MATER CHEM B, V6, P4645, DOI 10.1039/c8tb01100a
   Zhao JX, 2024, J COLLOID INTERF SCI, V669, P835, DOI 10.1016/j.jcis.2024.05.064
   Zheng KK, 2021, ADV FUNCT MATER, V31, DOI 10.1002/adfm.202102599
   Zheng WX, 2024, ACS APPL MATER INTER, V16, P49711, DOI 10.1021/acsami.4c06652
   Zhu YN, 2020, ADV FUNCT MATER, V30, DOI 10.1002/adfm.201905493
NR 73
TC 8
Z9 9
U1 13
U2 57
PU WILEY-V C H VERLAG GMBH
PI WEINHEIM
PA POSTFACH 101161, 69451 WEINHEIM, GERMANY
EI 2198-3844
J9 ADV SCI
JI Adv. Sci.
PD JAN
PY 2025
VL 12
IS 3
AR 2408077
DI 10.1002/advs.202408077
EA NOV 2024
PG 15
WC Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials
   Science, Multidisciplinary
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Chemistry; Science & Technology - Other Topics; Materials Science
GA U5Z5A
UT WOS:001364596900001
PM 39605188
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Alfarone, L
   Spadaccini, M
   Repici, A
   Hassan, C
   Maselli, R
AF Alfarone, Ludovico
   Spadaccini, Marco
   Repici, Alessandro
   Hassan, Cesare
   Maselli, Roberta
TI Management of perforations during endoscopic resection
SO BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY
LA English
DT Article
DE Cancer; Screening; Colonoscopy; Technology; Innovation
ID THE-SCOPE CLIP; VACUUM-ASSISTED CLOSURE; SUBMUCOSAL DISSECTION; ADVERSE
   EVENTS; CARBON-DIOXIDE; GI TRACT; EFFICACY; METAANALYSIS; DEFECTS;
   SURGERY
AB Despite the evolution in tools and techniques, perforation is still one of the most pernicious adverse events of therapeutic endoscopy with potentially huge consequences. As advanced endoscopic resection techniques are worldwide spreading, endoscopists must be ready to manage intraprocedural perforations. In fact, immediate endoscopic closure through a prompt diagnosis represents the first -line option, saving patients from surgery, long hospitalizations and worse outcomes. Traditional and novel endoscopic closure modalities, including clips, suturing devices, stents and vacuum therapy, are increasingly expanding the therapeutic armamentarium for closing these defects. Nevertheless, available literature on this topic is currently limited. In this review our goal is to give an overview on the management of perforations occurring during endoscopic resections, with particular attention to characteristics, advantages, disadvantages and new horizons of endoscopic closure tools.
C1 [Alfarone, Ludovico; Spadaccini, Marco; Repici, Alessandro; Hassan, Cesare; Maselli, Roberta] IRCCS, Humanitas Clin & Res Ctr, Endoscopy Unit, Rozzano, Italy.
   [Spadaccini, Marco; Repici, Alessandro; Hassan, Cesare; Maselli, Roberta] Humanitas Univ, Dept Biomed Sci, Pieve Emanuele, Italy.
   [Spadaccini, Marco] Humanitas Res Hosp & Univ, Via Manzoni 56, I-20089 Milan, Rozzano, Italy.
C3 IRCCS Humanitas Research Hospital; Humanitas University
RP Spadaccini, M (通讯作者)，Humanitas Res Hosp & Univ, Via Manzoni 56, I-20089 Milan, Rozzano, Italy.
EM marco.spadaccini@humanitas.it
RI Alfarone, Ludovico/LTF-4569-2024; Repici, Alessandro/HFH-8162-2022;
   hassan, cesare/H-2844-2012; Spadaccini, Marco/HOH-7613-2023; maselli,
   roberta/LFU-9657-2024
OI Alfarone, Ludovico/0000-0001-9702-4508; Repici,
   Alessandro/0000-0002-1621-6450; hassan, cesare/0000-0001-7167-1459;
   Spadaccini, Marco/0000-0003-3909-9012; 
CR Almario JA, 2023, ENDOSCOPY, V55, P865, DOI 10.1055/a-2077-4832
   Baniya R, 2017, CLIN ENDOSC, V50, P464, DOI 10.5946/ce.2016.161
   Bar-Yishay I, 2022, CLIN GASTROENTEROL H, V20, pE139, DOI 10.1016/j.cgh.2021.01.007
   Baron TH, 2012, GASTROINTEST ENDOSC, V76, P838, DOI 10.1016/j.gie.2012.04.476
   Bartell N, 2020, WORLD J GASTROENTERO, V26, P3495, DOI 10.3748/wjg.v26.i24.3495
   Bartell N, 2018, GASTROINTEST ENDOSC, V87, pAB248, DOI 10.1016/j.gie.2018.04.439
   Bi DS, 2023, GASTROINTEST ENDOSC, V98, P122, DOI 10.1016/j.gie.2023.02.031
   BINMOELLER KF, 1993, GASTROINTEST ENDOSC, V39, P172, DOI 10.1016/S0016-5107(93)70060-7
   Burgess NG, 2017, GUT, V66, P1779, DOI 10.1136/gutjnl-2015-309848
   Carrott PW, 2011, THORAC SURG CLIN, V21, P541, DOI 10.1016/j.thorsurg.2011.08.002
   Chaves J, 2023, Gastrointest Endosc.
   Chiapponi C, 2011, BMC GASTROENTEROL, V11, DOI 10.1186/1471-230X-11-48
   Dasari BVM, 2014, ANN SURG, V259, P852, DOI 10.1097/SLA.0000000000000564
   Ding X, 2019, EUR J GASTROEN HEPAT, V31, P1481, DOI 10.1097/MEG.0000000000001543
   Farha J, 2023, ENDOSCOPY, V55, P571, DOI 10.1055/a-1970-5528
   Ferlitsch M, 2017, ENDOSCOPY, V49, P270, DOI 10.1055/s-0043-102569
   Fujiya M, 2015, GASTROINTEST ENDOSC, V81, P583, DOI 10.1016/j.gie.2014.07.034
   Gupta S, 2022, LANCET GASTROENTEROL, V7, P152, DOI 10.1016/S2468-1253(21)00384-8
   Hagel AF, 2012, J GASTROINTEST SURG, V16, P2132, DOI 10.1007/s11605-012-1983-6
   Haito-Chavez Y, 2014, GASTROINTEST ENDOSC, V80, P610, DOI 10.1016/j.gie.2014.03.049
   Hassan C, 2016, GUT, V65, P806, DOI 10.1136/gutjnl-2014-308481
   Hernandez-Lara Ariosto, 2021, VideoGIE, V6, P243, DOI [10.1016/j.vgie.2021.02.015, 10.1016/j.vgie.2021.02.015]
   Honegger C, 2017, UNITED EUR GASTROENT, V5, P247, DOI 10.1177/2050640616657273
   Iwatsubo T, 2019, DIGEST DIS, V37, P53, DOI 10.1159/000492868
   Kamarajah SK, 2020, WORLD J SURG, V44, P1173, DOI 10.1007/s00268-019-05259-6
   Kantsevoy SV, 2016, GASTROINTEST ENDOSC, V84, P487, DOI 10.1016/j.gie.2015.08.074
   Kantsevoy SV, 2014, GASTROINTEST ENDOSC, V79, P503, DOI 10.1016/j.gie.2013.10.051
   Kato M, 2019, GASTROINTEST ENDOSC, V89, P87, DOI 10.1016/j.gie.2018.07.026
   Khater S, 2017, ENDOSC INT OPEN, V5, pE389, DOI 10.1055/s-0043-104862
   Kim SY, 2018, UNITED EUR GASTROENT, V6, P1089, DOI 10.1177/2050640618776740
   Kirschniak A, 2007, GASTROINTEST ENDOSC, V66, P162, DOI 10.1016/j.gie.2007.01.034
   Kobara H, 2019, J GASTROEN HEPATOL, V34, P22, DOI 10.1111/jgh.14402
   Kobayashi N, 2022, DIGEST ENDOSC, V34, P1042, DOI 10.1111/den.14223
   Kuehn F, 2017, SURG ENDOSC, V31, P3449, DOI 10.1007/s00464-016-5404-x
   Lee JH, 2021, CLIN GASTROENTEROL H, V19, P2252, DOI 10.1016/j.cgh.2021.06.045
   Lüning TH, 2007, SURG ENDOSC, V21, P994, DOI 10.1007/s00464-007-9251-7
   Martínek J, 2013, SURG ENDOSC, V27, P1203, DOI 10.1007/s00464-012-2576-x
   Martínez-Pérez A, 2017, WORLD J EMERG SURG, V12, DOI 10.1186/s13017-017-0121-x
   Maselli R, 2022, GASTROINTEST ENDOSC, V96, P780, DOI 10.1016/j.gie.2022.06.004
   Matthes K, 2011, GASTROINTEST ENDOSC, V74, P1369, DOI 10.1016/j.gie.2011.07.057
   Minami S, 2006, GASTROINTEST ENDOSC, V63, P596, DOI 10.1016/j.gie.2005.07.029
   Mudumbi S, 2014, ENDOSCOPY, V46, P1106, DOI 10.1055/s-0034-1377916
   Paspatis GA, 2020, ENDOSCOPY, V52, P792, DOI 10.1055/a-1222-3191
   Pimentel-Nunes P, 2022, ENDOSCOPY, V54, P591, DOI 10.1055/a-1811-7025
   Pohl H, 2019, GASTROENTEROLOGY, V157, P977, DOI 10.1053/j.gastro.2019.03.019
   Qiu JY, 2022, FRONT MED-LAUSANNE, V9, DOI 10.3389/fmed.2022.753956
   Raju GS, 2008, GASTROINTEST ENDOSC, V68, P324, DOI 10.1016/j.gie.2008.03.006
   Rausa E, 2018, DIS ESOPHAGUS, V31, DOI 10.1093/dote/doy060
   Saito Y, 2010, GASTROINTEST ENDOSC, V72, P1217, DOI 10.1016/j.gie.2010.08.004
   Spadaccini M, 2020, GASTROENTEROLOGY, V159, P148, DOI 10.1053/j.gastro.2020.03.051
   Swan MP, 2011, GASTROINTEST ENDOSC, V73, P79, DOI 10.1016/j.gie.2010.07.003
   Takamaru H, 2016, GASTROINTEST ENDOSC, V84, P494, DOI 10.1016/j.gie.2016.01.014
   Toyonaga T, 2013, SURG ENDOSC, V27, P1000, DOI 10.1007/s00464-012-2555-2
   Trieu JA, 2023, Gastrointest Endosc, P2902
   van Boeckel PGA, 2011, ALIMENT PHARM THER, V33, P1292, DOI 10.1111/j.1365-2036.2011.04663.x
   Verlaan T, 2015, GASTROINTEST ENDOSC, V82, P618, DOI 10.1016/j.gie.2015.03.1977
   Voermans RP, 2012, CLIN GASTROENTEROL H, V10, P603, DOI 10.1016/j.cgh.2012.02.005
   von Renteln D, 2009, ENDOSCOPY, V41, P1056, DOI 10.1055/s-0029-1215241
   von Renteln D, 2008, GASTROINTEST ENDOSC, V67, P738, DOI 10.1016/j.gie.2007.10.051
   Wang TJ, 2019, GASTROINTEST ENDOSC, V89, P77, DOI 10.1016/j.gie.2018.07.025
   Watanabe D, 2019, DIGEST LIVER DIS, V51, P774, DOI 10.1016/j.dld.2019.03.021
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Wei Mike Tzuhen, 2023, VideoGIE, V8, P245, DOI [10.1016/j.vgie.2023.02.002, 10.1016/j.vgie.2023.02.002]
   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
   Yahagi N, 2018, GASTROINTEST ENDOSC, V88, P676, DOI 10.1016/j.gie.2018.05.002
   Yamamoto Y, 2019, DIGEST ENDOSC, V31, P4, DOI 10.1111/den.13388
   Yang DH, 2010, SURG ENDOSC, V24, P1177, DOI 10.1007/s00464-009-0746-2
   Zhu SM, 2019, SURG ENDOSC, V33, P1319, DOI 10.1007/s00464-018-6586-1
NR 68
TC 3
Z9 4
U1 0
U2 2
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1521-6918
EI 1532-1916
J9 BEST PRACT RES CL GA
JI Best Pract. Res. Clin. Gastroenterol.
PD MAR
PY 2024
VL 69
AR 101900
DI 10.1016/j.bpg.2024.101900
EA MAY 2024
PG 9
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA TL9E6
UT WOS:001241527400001
PM 38749581
DA 2026-07-24
ER

PT J
AU Ocker, L
   Rached, NA
   Seifert, C
   Scheel, C
   Bechara, FG
AF Ocker, Lennart
   Rached, Nessr Abu
   Seifert, Caroline
   Scheel, Christina
   Bechara, Falk G.
TI Current Medical and Surgical Treatment of Hidradenitis Suppurativa-A
   Comprehensive Review
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Review
DE hidradenitis suppurativa; acne inversa; dermatology; inflammation;
   treatment; adalimumab; targeted therapy; small molecules
ID QUALITY-OF-LIFE; TISSUE-SPARING EXCISION; VACUUM-ASSISTED CLOSURE;
   AXILLARY HIDRADENITIS; DOUBLE-BLIND; ADALIMUMAB ORIGINATOR;
   CYPROTERONE-ACETATE; SEVERITY ASSESSMENT; PROSPECTIVE SERIES;
   CLINICAL-RESPONSE
AB Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact on patients' quality of life and is associated with a variety of comorbidities. Treatment of HS is often complex, requiring an individual approach with medical and surgical treatments available. However, especially in moderate-to-severe HS, there is an urgent need for new treatment approaches. In recent years, increased research has led to the identification of new potential therapeutic targets. This review aims to give a comprehensive and practical overview of current treatment options for HS. Furthermore, the clinically most advanced novel treatment approaches will be discussed.
C1 [Ocker, Lennart; Rached, Nessr Abu; Seifert, Caroline; Scheel, Christina; Bechara, Falk G.] Ruhr Univ Bochum, Int Ctr Hidradenitis Suppurativa Acne Inversa ICH, Dept Dermatol Venereol & Allergol, D-44791 Bochum, Germany.
C3 Ruhr University Bochum
RP Ocker, L; Bechara, FG (通讯作者)，Ruhr Univ Bochum, Int Ctr Hidradenitis Suppurativa Acne Inversa ICH, Dept Dermatol Venereol & Allergol, D-44791 Bochum, Germany.
EM lennart.ocker@kklbo.de; falk.bechara@kklbo.de
RI Ocker, Lennart/LBH-0077-2024; Scheel, Christina/IQV-1110-2023; Abu
   Rached, Nessr/HGE-3011-2022
OI Bechara, Falk/0000-0003-0418-521X; Abu Rached, Nessr/0000-0001-6853-0743
FU Ruhr-Universitat Bochum
FX This research received no external funding, except for the Open Access
   Publication Funds of the Ruhr-Universitat Bochum.
CR AbbVie, 2022, A Phase 2 Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Safety and Efficacy of Lutikizumab (ABT-981) in Adult Subjects With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy
   Adams DR, 2010, ARCH DERMATOL, V146, P501, DOI 10.1001/archdermatol.2010.72
   Afsharfard A, 2020, WORLD J PLAST SURG, V9, P55, DOI 10.29252/wjps.9.1.55
   Alavi A, 2022, BRIT J DERMATOL, V186, P803, DOI 10.1111/bjd.20969
   Alballa Nouf, 2018, AME Case Rep, V2, P49, DOI [10.21037/acr.2018.12.01, 10.21037/acr.2018.12.01]
   Albrecht J, 2019, BRIT J DERMATOL, V180, P949, DOI 10.1111/bjd.17422
   Alharbi Z, 2012, BMC DERMATOL, V12, DOI 10.1186/1471-5945-12-9
   Alikhan A, 2019, J AM ACAD DERMATOL, V81, P91, DOI 10.1016/j.jaad.2019.02.068
   André R, 2019, INT J DERMATOL, V58, pE208, DOI 10.1111/ijd.14596
   [Anonymous], SCI MOONLAKE
   Armyra K, 2017, INT J DERMATOL, V56, P346, DOI 10.1111/ijd.13428
   Azim AAA, 2018, INT J DERMATOL, V57, P1135, DOI 10.1111/ijd.14075
   Bechara FG, 2021, JAMA SURG, V156, P1001, DOI 10.1001/jamasurg.2021.3655
   Behrens F, 2022, ANN RHEUM DIS, V81, P170, DOI 10.1136/annrheumdis-2022-eular.536
   Blok JL, 2015, J EUR ACAD DERMATOL, V29, P379, DOI 10.1111/jdv.12376
   Boer J, 2011, BRIT J DERMATOL, V164, P170, DOI 10.1111/j.1365-2133.2010.10071.x
   Boer J, 1999, J AM ACAD DERMATOL, V40, P73, DOI 10.1016/S0190-9622(99)70530-X
   Boer J, 2010, CLIN EXP DERMATOL, V35, P36, DOI 10.1111/j.1365-2230.2009.03377.x
   Brandwein M, 2019, Human Microbiome Journal, V13, P100063, DOI [10.1016/j.humic.2019.100063, 10.1016/j.humic.2019.100063, DOI 10.1016/J.HUMIC.2019.100063]
   Braunberger TL, 2018, INT J DERMATOL, V57, P1088, DOI 10.1111/ijd.14036
   Brocard A, 2011, J EUR ACAD DERMATOL, V25, P1146, DOI 10.1111/j.1468-3083.2010.03934.x
   Brocard A, 2007, DERMATOLOGY, V214, P325, DOI 10.1159/000100883
   Burlando M, 2022, BIOMEDICINES, V10, DOI 10.3390/biomedicines10102522
   Busnardo FF, 2011, PLAST RECONSTR SURG, V128, P949, DOI 10.1097/PRS.0b013e3182268c38
   Cagalj AM, 2022, INT J MOL SCI, V23, DOI 10.3390/ijms23073753
   Canard C, 2021, ACTA DERM-VENEREOL, V101, DOI 10.2340/00015555-3830
   Casseres RG, 2020, J AM ACAD DERMATOL, V82, P1524, DOI 10.1016/j.jaad.2020.02.005
   Chahine A, 2018, J AM ACAD DERMATOL, V79, pAB133
   Chen E, 2011, ANN PLAS SURG, V67, P397, DOI 10.1097/SAP.0b013e3181f77bd6
   Civelek B, 2010, CENT EUR J MED, V5, P674, DOI 10.2478/s11536-009-0126-2
   Clark A.K., 2017, Dermatol Online J, V23, P23
   CLEMMENSEN OJ, 1983, INT J DERMATOL, V22, P325, DOI 10.1111/j.1365-4362.1983.tb02150.x
   Coghlan J, 2021, J PHARM SCI-US, V110, P1572, DOI 10.1016/j.xphs.2021.02.003
   Collier Erin K, 2020, Int J Womens Dermatol, V6, P372, DOI [10.1016/j.ijwd.2020.09.002, 10.1016/j.ijwd.2020.09.002]
   CORVOL P, 1975, ENDOCRINOLOGY, V97, P52, DOI 10.1210/endo-97-1-52
   Cramer P, 2021, HAUTARZT, V72, P692, DOI 10.1007/s00105-021-04864-8
   Dahmen RA, 2019, J DTSCH DERMATOL GES, V17, P698, DOI 10.1111/ddg.13875
   DALRYMPLE JC, 1987, BRIT J SURG, V74, P420, DOI 10.1002/bjs.1800740535
   Damsky W, 2017, J AM ACAD DERMATOL, V76, P736, DOI 10.1016/j.jaad.2016.12.005
   Darlenski R, 2022, FRONT NUTR, V9, DOI 10.3389/fnut.2022.855573
   Deckers IE, 2018, J EUR ACAD DERMATOL, V32, P459, DOI 10.1111/jdv.14770
   Deckers IE, 2017, J AM ACAD DERMATOL, V76, P49, DOI 10.1016/j.jaad.2016.08.031
   Egeberg A, 2016, JAMA DERMATOL, V152, P429, DOI 10.1001/jamadermatol.2015.6264
   Elkin K, 2020, SKIN RES TECHNOL, V26, P3, DOI 10.1111/srt.12772
   Esmann S, 2011, ACTA DERM-VENEREOL, V91, P328, DOI 10.2340/00015555-1082
   Esme P, 2021, SKIN APPENDAGE DISOR, V7, P58, DOI 10.1159/000511284
   Ezanno AC, 2022, INT WOUND J, V19, P802, DOI 10.1111/iwj.13678
   Fauny M, 2020, ANN RHEUM DIS, V79, P1132, DOI 10.1136/annrheumdis-2020-217927
   Fleischmann RM, 2019, ARTHRITIS RHEUMATOL, V71, P1056, DOI 10.1002/art.40840
   Fletcher JM, 2020, CLIN EXP IMMUNOL, V201, P121, DOI 10.1111/cei.13449
   Frieder J, 2018, THER ADV CHRONIC DIS, V9, P5, DOI 10.1177/2040622317738910
   Gallagher CG, 2019, CLIN EXP DERMATOL, V44, P777, DOI 10.1111/ced.13944
   Gallagher Catriona, 2017, JAAD Case Rep, V3, P436, DOI [10.1016/j.jdcr.2017.06.008, 10.1016/j.jdcr.2017.06.008]
   Garg A, 2022, J AM ACAD DERMATOL, V86, P1092, DOI 10.1016/j.jaad.2021.01.059
   Garg A, 2018, J INVEST DERMATOL, V138, P1288, DOI 10.1016/j.jid.2018.01.009
   Garg A, 2017, JAMA DERMATOL, V153, P760, DOI 10.1001/jamadermatol.2017.0201
   Geh JLC, 2002, BRIT J PLAST SURG, V55, P124, DOI 10.1054/bjps.2001.3783
   Gener G, 2009, DERMATOLOGY, V219, P148, DOI 10.1159/000228334
   Ghanian S, 2022, AM J CLIN DERMATOL, V23, P167, DOI 10.1007/s40257-021-00667-8
   Gimeno-Gracia M, 2019, EXPERT OPIN BIOL TH, V19, P1031, DOI 10.1080/14712598.2019.1561851
   Glatt S, 2021, JAMA DERMATOL, V157, P1279, DOI 10.1001/jamadermatol.2021.2905
   Golbari NM, 2019, J AM ACAD DERMATOL, V80, P114, DOI 10.1016/j.jaad.2018.06.063
   GORKIOSCH K, 1984, Handchirurgie Mikrochirurgie Plastische Chirurgie, V16, P135
   Gottlieb A, 2020, J INVEST DERMATOL, V140, P1538, DOI 10.1016/j.jid.2019.10.024
   Grant A, 2010, J AM ACAD DERMATOL, V62, P205, DOI 10.1016/j.jaad.2009.06.050
   Gulliver W, 2016, REV ENDOCR METAB DIS, V17, P343, DOI 10.1007/s11154-016-9328-5
   Hamzavi IH, 2015, J AM ACAD DERMATOL, V73, pS78, DOI 10.1016/j.jaad.2015.07.050
   Hazen PG, 2010, DERMATOL SURG, V36, P208, DOI 10.1111/j.1524-4725.2009.01427.x
   Hessam S, 2018, JAMA DERMATOL, V154, P330, DOI 10.1001/jamadermatol.2017.5890
   Hessam S, 2016, J DERMATOL SCI, V84, P197, DOI 10.1016/j.jdermsci.2016.08.010
   Holm JG, 2020, DERMATOL THER, V33, DOI 10.1111/dth.14494
   Houriet C, 2017, JAMA DERMATOL, V153, P1195, DOI 10.1001/jamadermatol.2017.2392
   Hu XY, 2021, SIGNAL TRANSDUCT TAR, V6, DOI 10.1038/s41392-021-00791-1
   Humphries LS, 2016, J PLAST RECONSTR AES, V69, P554, DOI 10.1016/j.bjps.2015.12.004
   Hurley H J., 1996, Dermatologic surgery:principles and practice, V2nd, P623
   Iznardo H, 2022, INT J MOL SCI, V23, DOI 10.3390/ijms23169479
   Jafari SMS, 2020, FRONT MED-LAUSANNE, V7, DOI 10.3389/fmed.2020.00068
   Jain Vivek, 2012, J Cutan Aesthet Surg, V5, P190, DOI 10.4103/0974-2077.101377
   Janse I, 2016, DERMATOL CLIN, V34, P97, DOI 10.1016/j.det.2015.08.007
   Janse IC, 2016, ACTA DERM-VENEREOL, V96, P390, DOI 10.2340/00015555-2258
   Janssen Research & Development LLC, 2022, JNJ 77474462 TREATM
   Jarvis B, 1999, DRUGS, V57, P945, DOI 10.2165/00003495-199957060-00014
   Jemec GBE, 1998, J AM ACAD DERMATOL, V39, P971, DOI 10.1016/S0190-9622(98)70272-5
   Jemec GBE, 1996, J AM ACAD DERMATOL, V35, P191, DOI 10.1016/S0190-9622(96)90321-7
   Jennings L, 2020, J DERMATOL TREAT, V31, P261, DOI 10.1080/09546634.2019.1592100
   Jfri A, 2021, JAMA DERMATOL, V157, P924, DOI 10.1001/jamadermatol.2021.1677
   Jfri A, 2020, FRONT MED-LAUSANNE, V7, DOI 10.3389/fmed.2020.591580
   Johnston A, 2013, J IMMUNOL, V190, P2252, DOI 10.4049/jimmunol.1201505
   Join-Lambert O, 2016, J ANTIMICROB CHEMOTH, V71, P513, DOI 10.1093/jac/dkv361
   Join-Lambert O, 2014, EUR J DERMATOL, V24, P94, DOI 10.1684/ejd.2013.2213
   Join-Lambert O, 2011, DERMATOLOGY, V222, P49, DOI 10.1159/000321716
   Jorgensen AHR, 2021, INT J DERMATOL, V60, P785, DOI 10.1111/ijd.15459
   Kamp S, 2011, BRIT J DERMATOL, V164, P1017, DOI 10.1111/j.1365-2133.2011.10224.x
   Kanni T, 2021, CLIN EXP DERMATOL, V46, P162, DOI 10.1111/ced.14333
   Kanni T, 2018, J INVEST DERMATOL, V138, P795, DOI 10.1016/j.jid.2017.10.030
   Kelekis NL, 2010, BRIT J DERMATOL, V162, P1400, DOI 10.1111/j.1365-2133.2010.09710.x
   Kelly G, 2015, BRIT J DERMATOL, V173, P1431, DOI 10.1111/bjd.14075
   Khan A, 2022, CLIN DERMATOL, V40, P114, DOI 10.1016/j.clindermatol.2022.04.001
   Kimball AB, 2016, J EUR ACAD DERMATOL, V30, P989, DOI 10.1111/jdv.13216
   Kimball AB, 2014, BRIT J DERMATOL, V171, P1434, DOI 10.1111/bjd.13270
   Kimball A.B., 2022, P 31 EUROPEAN ACAD D
   Kimball AB, 2016, NEW ENGL J MED, V375, P422, DOI 10.1056/NEJMoa1504370
   Kimball AB, 2012, ANN INTERN MED, V157, P846, DOI 10.7326/0003-4819-157-12-201212180-00004
   Kirby J.S., 2022, EXPLORATORY TRIAL RU
   Kirsten N, 2022, LIFE-BASEL, V12, DOI 10.3390/life12101518
   Kitts S, 2021, CLIN EXP DERMATOL, V46, P582, DOI 10.1111/ced.14512
   Kohorst JJ, 2016, DERMATOL SURG, V42, P1030, DOI 10.1097/DSS.0000000000000806
   Kokolakis G, 2020, DERMATOLOGY, V236, P421, DOI 10.1159/000508787
   Kokolakis G, 2018, JAMA DERMATOL, V154, P971, DOI 10.1001/jamadermatol.2018.1599
   Kozera E, 2022, J AM ACAD DERMATOL, V87, P1440, DOI 10.1016/j.jaad.2022.07.047
   Kraft JN, 2007, J CUTAN MED SURG, V11, P125, DOI 10.2310/7750.2007.00019
   Kromann CB, 2014, BRIT J DERMATOL, V171, P819, DOI 10.1111/bjd.13090
   Kromann CB, 2014, ACTA DERM-VENEREOL, V94, P553, DOI 10.2340/00015555-1800
   Lacy SE, 2015, MABS-AUSTIN, V7, P605, DOI 10.1080/19420862.2015.1026501
   LAPINS J, 1994, BRIT J DERMATOL, V131, P551
   Lapins J, 2002, J AM ACAD DERMATOL, V47, P280, DOI 10.1067/mjd.2002.124601
   Layton A, 2009, DERM-ENDOCRINOL, V1, P162, DOI 10.4161/derm.1.3.9364
   Lee A, 2015, AUSTRALAS J DERMATOL, V56, P192, DOI 10.1111/ajd.12362
   Leslie KS, 2014, J AM ACAD DERMATOL, V70, P243, DOI 10.1016/j.jaad.2013.09.044
   Lin CH, 2016, DERMATOL SURG, V42, P273, DOI 10.1097/DSS.0000000000000609
   Lu JW, 2021, MEDICINE, V100, DOI 10.1097/MD.0000000000026190
   Mac Mahon J, 2020, PATIENT-RELAT OUTCOM, V11, P21, DOI 10.2147/PROM.S174299
   Maclean GM, 2007, ANN ROY COLL SURG, V89, P709, DOI 10.1308/003588407X209392
   Mahmoud BH, 2010, J AM ACAD DERMATOL, V62, P637, DOI 10.1016/j.jaad.2009.07.048
   Mandal A, 2005, SURG-J R COLL SURG E, V3, P23, DOI 10.1016/S1479-666X(05)80006-X
   Marasca C, 2020, EXPERT REV CLIN PHAR, V13, P521, DOI 10.1080/17512433.2020.1762571
   Martora F, 2022, CLIN EXP DERMATOL, V47, P1864, DOI 10.1111/ced.15291
   Martora F, 2022, SKIN APPENDAGE DISOR, V8, P265, DOI 10.1159/000521712
   Marzano AV, 2021, BRIT J DERMATOL, V184, P133, DOI 10.1111/bjd.18983
   Matusiak L, 2014, BRIT J DERMATOL, V171, P170, DOI 10.1111/bjd.12884
   Matusiak L, 2010, J AM ACAD DERMATOL, V62, P706, DOI 10.1016/j.jaad.2009.09.021
   Mehdizadeh A, 2015, J AM ACAD DERMATOL, V73, pS70, DOI 10.1016/j.jaad.2015.07.044
   Mekkes JR, 2008, BRIT J DERMATOL, V158, P370, DOI 10.1111/j.1365-2133.2007.08332.x
   Melendez-Gonzalez MD, 2021, J INVEST DERMATOL, V141, P2975, DOI [10.17632/fwjvy294wy.1, 10.1016/j.jid.2021.04.026]
   Melnik BC, 2018, BRIT J DERMATOL, V179, P260, DOI 10.1111/bjd.16561
   Menderes A, 2010, INT J MED SCI, V7, P240
   Mendonça CO, 2006, BRIT J DERMATOL, V154, P977, DOI 10.1111/j.1365-2133.2006.07155.x
   Menis D, 2015, BRIT J DERMATOL, V172, P810, DOI 10.1111/bjd.13292
   Mertens M, 2009, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD005121.pub3
   Mikkelsen PR, 2015, DERMATOL SURG, V41, P255, DOI 10.1097/DSS.0000000000000264
   Mills KHG, 2023, NAT REV IMMUNOL, V23, P38, DOI 10.1038/s41577-022-00746-9
   Mokos ZB, 2020, ACTA DERMATOVENER CR, V28, P9
   Molinelli E, 2022, DERMATOL THER, V35, DOI 10.1111/dth.15439
   Molinelli E, 2020, J AM ACAD DERMATOL, V83, P665, DOI 10.1016/j.jaad.2020.04.092
   Monfrecola G., 2017, Hidradenitis suppurativa: a diagnostic atlas, V1st, P39
   Montero-Vilchez T, 2022, J CLIN MED, V11, DOI 10.3390/jcm11041007
   MoonLake Immunotherapeutics A.G, 2022, PHASE 2 RANDOMIZED P
   MORGAN WP, 1983, ANN ROY COLL SURG, V65, P235
   MORTIMER PS, 1986, BRIT J DERMATOL, V115, P263, DOI 10.1111/j.1365-2133.1986.tb05740.x
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Moussa C, 2020, J DRUGS DERMATOL, V19, P1231, DOI 10.36849/JDD.2020.5447
   Muralidharan V, 2021, DERMATOL THER, V34, DOI 10.1111/dth.14643
   Napolitano M, 2017, CLIN COSMET INV DERM, V10, P105, DOI 10.2147/CCID.S111019
   Navrazhina K, 2020, BRIT J DERMATOL, V182, P1045, DOI 10.1111/bjd.18556
   Nazzaro G, 2021, ITAL J DERMATOL VENE, V156, P235, DOI 10.23736/S2784-8671.18.06196-5
   Nazzaro G, 2021, DERMATOL THER, V34, DOI 10.1111/dth.14706
   Nesmith RB, 2013, ANN PLAS SURG, V70, P538, DOI 10.1097/SAP.0b013e31828ea7cb
   Niemi M, 2003, CLIN PHARMACOKINET, V42, P819, DOI 10.2165/00003088-200342090-00003
   Ovadja ZN, 2021, DERMATOL SURG, V47, pE106, DOI 10.1097/DSS.0000000000002815
   Oxford Centre for Evidence-Based Medicine, 2009, LEVELS EVIDENCE
   Papp KA, 2021, LANCET, V397, P1564, DOI 10.1016/S0140-6736(21)00440-2
   Patel KR, 2020, J AM ACAD DERMATOL, V83, P737, DOI 10.1016/j.jaad.2019.11.068
   Patel N, 2021, J DERMATOL TREAT, V32, P473, DOI 10.1080/09546634.2019.1670779
   Phan K, 2020, ANN TRANSL MED, V8, DOI 10.21037/atm-20-1028
   POPE ER, 1990, VET CLIN N AM-SMALL, V20, P177, DOI 10.1016/S0195-5616(90)50009-1
   Prussick L, 2019, BRIT J DERMATOL, V181, P609, DOI 10.1111/bjd.17822
   Quinlan C, 2020, CLIN EXP DERMATOL, V45, P464, DOI 10.1111/ced.14119
   Reguiaï Z, 2020, J EUR ACAD DERMATOL, V34, pE750, DOI 10.1111/jdv.16605
   Revuz JE, 2008, J AM ACAD DERMATOL, V59, P596, DOI 10.1016/j.jaad.2008.06.020
   Ribero S, 2021, J EUR ACAD DERMATOL, V35, pE441, DOI 10.1111/jdv.17178
   Ricceri F, 2020, DERMATOL THER, V33, DOI 10.1111/dth.14387
   Richette P, 2014, J RHEUMATOL, V41, P490, DOI 10.3899/jrheum.130977
   Riis PT, 2019, BRIT J DERMATOL, V180, P774, DOI 10.1111/bjd.16998
   Riis PT, 2017, BRIT J DERMATOL, V176, P1083, DOI 10.1111/bjd.14922
   Riis PT, 2016, J AM ACAD DERMATOL, V75, P1151, DOI 10.1016/j.jaad.2016.06.049
   Ritz JP, 1998, INT J COLORECTAL DIS, V13, P164, DOI 10.1007/s003840050159
   Roccuzzo G, 2022, DERMATOL THER, V35, DOI 10.1111/dth.15803
   Rompel R, 2000, DERMATOL SURG, V26, P638, DOI 10.1046/j.1524-4725.2000.00043.x
   Rondags A, 2019, BRIT J DERMATOL, V180, P1214, DOI 10.1111/bjd.17508
   Russo V, 2016, J DRUGS DERMATOL, V15, P772
   Sabat R, 2020, NAT REV DIS PRIMERS, V6, DOI 10.1038/s41572-020-0149-1
   Sabat R, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0031810
   Sampogna F, 2017, ACTA DERM-VENEREOL, V97, P478, DOI 10.2340/00015555-2561
   Sánchez-Díaz M, 2023, DERMATOLOGY, V239, P52, DOI 10.1159/000526019
   Sand FL, 2015, DERMATOL THER, V28, P158, DOI 10.1111/dth.12222
   Sartorius K, 2003, BRIT J DERMATOL, V149, P211, DOI 10.1046/j.1365-2133.2003.05390.x
   Sartorius K, 2009, BRIT J DERMATOL, V161, P831, DOI 10.1111/j.1365-2133.2009.09198.x
   Saunte DM, 2015, BRIT J DERMATOL, V173, P1546, DOI 10.1111/bjd.14038
   Savage KT, 2021, J AM ACAD DERMATOL, V85, P187, DOI 10.1016/j.jaad.2020.09.039
   SAWERS RS, 1986, BRIT J DERMATOL, V115, P269, DOI 10.1111/j.1365-2133.1986.tb05741.x
   Schlapbach C, 2011, J AM ACAD DERMATOL, V65, P790, DOI 10.1016/j.jaad.2010.07.010
   Scholl L, 2018, HAUTARZT, V69, P149, DOI 10.1007/s00105-017-4114-1
   Schwabegger AH, 2000, BRIT J PLAST SURG, V53, P676, DOI 10.1054/bjps.2000.3443
   Scuderi N, 2017, SKIN APPENDAGE DISOR, V3, P95, DOI 10.1159/000462979
   Shalom G, 2015, BRIT J DERMATOL, V173, P464, DOI 10.1111/bjd.13777
   Shih T, 2022, DERMATOL THER, V35, DOI 10.1111/dth.15691
   Shlyankevich J, 2014, J AM ACAD DERMATOL, V71, P1144, DOI 10.1016/j.jaad.2014.09.012
   Shukla R, 2022, J CLIN MED, V11, DOI 10.3390/jcm11092311
   Smith HS, 2010, CLIN J PAIN, V26, P435, DOI 10.1097/AJP.0b013e3181ceb80c
   Solanki N S, 2009, J Wound Care, V18, P111
   Soria A, 2009, DERMATOLOGY, V218, P134, DOI 10.1159/000182261
   Sun Natalie Z, 2017, J Clin Aesthet Dermatol, V10, P36
   Svecova D, 2019, J AM ACAD DERMATOL, V81, P196, DOI 10.1016/j.jaad.2019.03.056
   Tan MG, 2017, J CUTAN MED SURG, V21, P48, DOI 10.1177/1203475416659858
   Tekin B, 2017, INDIAN J DERMATOL VE, V83, P615, DOI 10.4103/ijdvl.IJDVL_147_16
   Tierney E, 2009, DERMATOL SURG, V35, P1188, DOI 10.1111/j.1524-4725.2009.01214.x
   Timila Touhouche Assia, 2020, Int J Womens Dermatol, V6, P164, DOI [10.1016/j.ijwd.2020.02.006, 10.1016/j.ijwd.2020.02.006]
   Tursi A, 2016, DIGEST LIVER DIS, V48, P1511, DOI 10.1016/j.dld.2016.09.010
   Tzanetakou V, 2016, JAMA DERMATOL, V152, P52, DOI 10.1001/jamadermatol.2015.3903
   Tzellos T, 2023, J EUR ACAD DERMATOL, V37, P395, DOI 10.1111/jdv.18632
   Vaillant C, 2022, J CLIN MED, V11, DOI 10.3390/jcm11195813
   van der Zee HH, 2013, DERMATOLOGY, V226, P97, DOI 10.1159/000343221
   van der Zee HH, 2010, J AM ACAD DERMATOL, V63, P475, DOI 10.1016/j.jaad.2009.12.018
   van der Zee HH, 2009, DERMATOLOGY, V219, P143, DOI 10.1159/000228337
   van Hattem S, 2012, DERMATOL SURG, V38, P494, DOI 10.1111/j.1524-4725.2011.02255.x
   van Rappard DC, 2012, J EUR ACAD DERMATOL, V26, P898, DOI 10.1111/j.1468-3083.2011.04203.x
   Varkarakis G, 2010, ANN PLAS SURG, V64, P592, DOI 10.1097/SAP.0b013e3181da1c4f
   Verdolini R, 2013, J EUR ACAD DERMATOL, V27, P1101, DOI 10.1111/j.1468-3083.2012.04668.x
   Vural S, 2019, DERMATOL THER, V32, DOI 10.1111/dth.13003
   Wahab A, 2020, CLIN CASE REP, V8, P1666, DOI 10.1002/ccr3.2987
   Witte-Händel E, 2019, J INVEST DERMATOL, V139, P1294, DOI 10.1016/j.jid.2018.11.018
   Wolkenstein P, 2007, J AM ACAD DERMATOL, V56, P621, DOI 10.1016/j.jaad.2006.08.061
   Wong AK, 2012, CLIN RHEUMATOL, V31, P631, DOI 10.1007/s10067-011-1895-y
   Wortsman X, 2013, DERMATOL SURG, V39, P1835, DOI 10.1111/dsu.12329
   Wynalda MA, 2003, DRUG METAB DISPOS, V31, P878, DOI 10.1124/dmd.31.7.878
   Wynne C, 2016, EXPERT OPIN INV DRUG, V25, P1361, DOI 10.1080/13543784.2016.1255724
   Xu LSY, 2011, ARCH DERMATOL, V147, P21, DOI 10.1001/archdermatol.2010.245
   Yao Y, 2021, BRIT J DERMATOL, V184, P552, DOI 10.1111/bjd.19578
   Yao Y., 2017, DERMATOL J, V23, P1, DOI [DOI 10.5070/D3237035729, 10.5070/D3237035729]
   Zarchi K, 2013, JAMA DERMATOL, V149, P1192, DOI 10.1001/jamadermatol.2013.5377
   Zouboulis CC, 2017, BRIT J DERMATOL, V177, P1401, DOI 10.1111/bjd.15748
   Zouboulis CC, 2015, J EUR ACAD DERMATOL, V29, P619, DOI 10.1111/jdv.12966
   Zouboulis CC, 2021, EXP DERMATOL, V30, P8, DOI 10.1111/exd.14338
   Zouboulis CC, 2019, J AM ACAD DERMATOL, V80, P60, DOI 10.1016/j.jaad.2018.05.040
NR 234
TC 45
Z9 50
U1 0
U2 10
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD DEC
PY 2022
VL 11
IS 23
AR 7240
DI 10.3390/jcm11237240
PG 27
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 6Y8RD
UT WOS:000897354600001
PM 36498816
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Janis, J
   Harrison, B
AF Janis, Jeffrey
   Harrison, Bridget
TI Wound Healing: Part II. Clinical Applications
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; TISSUE ADHESIVE 2-OCTYLCYANOACRYLATE;
   MICROVASCULAR BLOOD-FLOW; PLATELET-RICH PLASMA; NEGATIVE-PRESSURE;
   COST-EFFECTIVENESS; HYPERBARIC-OXYGEN; CONTROLLED-TRIAL;
   POVIDONE-IODINE; DERMAL ULCERS
AB Learning Objectives: After studying this article, the participant should be able to: 1. Identify effective methods for irrigation and debridement of wounds. 2. Describe methods for optimal closure of a wound. 3. Develop an algorithm for postoperative scar management. 4. Appreciate adjunctive clinical tools that may facilitate improvements in wound healing.
   Summary: Treatment of all wounds requires adequate wound bed preparation, beginning with irrigation and debridement. Complicated or chronic wounds may also require treatment adjuncts or specialized wound healing products. An extensive body of research and development has introduced novel wound healing therapies and scar management options. In this second of a two-part continuing medical education series on wound healing, the reader is offered an update on current wound healing technologies and recommendations for obtaining optimal outcomes.
C1 [Janis, Jeffrey; Harrison, Bridget] Univ Texas SW Med Ctr Dallas, Dept Plast Surg, Dallas, TX 75390 USA.
C3 University of Texas System; University of Texas Southwestern Medical
   Center
RP Janis, J (通讯作者)，Ohio State Univ, Med Ctr, Dept Plast Surg, 915 Olentangy River Rd,2nd Floor, Columbus, OH 43212 USA.
EM jeffrey.janis@osumc.edu
RI Janis, Jeffrey/W-6760-2019
OI Janis, Jeffrey/0000-0001-6103-4798
CR Akita S, 2010, STEM CELLS INT, V2010, DOI 10.4061/2010/532704
   Al-Waili NS, 2011, J MED FOOD, V14, P1079, DOI 10.1089/jmf.2010.0161
   Allan N, 2010, WOUND REPAIR REGEN, V18, pA88
   Alsousou J, 2009, J BONE JOINT SURG BR, V91B, P987, DOI 10.1302/0301-620X.91B8.22546
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Atiyeh BS, 2009, INT WOUND J, V6, P420, DOI 10.1111/j.1742-481X.2009.00639.x
   Attinger CE, 2006, PLAST RECONSTR SURG, V117, p72S, DOI 10.1097/01.prs.0000225470.42514.8f
   Baumann LS, 1999, DERMATOL SURG, V25, P311, DOI 10.1046/j.1524-4725.1999.08223.x
   Bennett MH, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD005005.pub3
   Berman B, 2007, DERMATOL SURG, V33, P1291, DOI 10.1111/j.1524-4725.2007.33280.x
   Bhandari M, 2011, J TRAUMA, V71, P596, DOI 10.1097/TA.0b013e3181f6f2e8
   Blaser G, 2007, J Wound Care, V16, P325
   Borgquist O, 2011, WOUND REPAIR REGEN, V19, P727, DOI 10.1111/j.1524-475X.2011.00741.x
   BOXER AM, 1969, GERIATRICS, V24, P75
   Boyd JI III, 2004, CLIN ORTHOP RELAT R, P13, DOI 10.1097/01.blo.0000144859.73074.45
   Boykin J V, 2001, Adv Skin Wound Care, V14, P234, DOI 10.1097/00129334-200109000-00008
   Boykin JV, 2001, ADV SKIN WOUND CARE, V14, P234
   BROWN LL, 1978, ANN SURG, V187, P170, DOI 10.1097/00000658-197802000-00013
   BUCKNALL TE, 1983, ANN ROY COLL SURG, V65, P71
   Chang WK, 2012, ANN SURG, V255, P854, DOI 10.1097/SLA.0b013e31824e7005
   CHANTARASAK ND, 1989, BRIT J PLAST SURG, V42, P687, DOI 10.1016/0007-1226(89)90082-9
   Chlebicki MP, 2013, AM J INFECT CONTROL, V41, P167, DOI 10.1016/j.ajic.2012.02.014
   Chung VQ, 2006, DERMATOL SURG, V32, P193, DOI 10.1111/j.1524-4725.2006.32045.x
   COLDIRON BM, 1989, ARCH DERMATOL, V125, P1189, DOI 10.1001/archderm.125.9.1189
   Coulthard P, 2010, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004287.pub3
   Dash NR, 2009, REJUV RES, V12, P359, DOI 10.1089/rej.2009.0872
   Desai KK, 2012, CLIN PLAST SURG, V39, P311, DOI 10.1016/j.cps.2012.05.002
   Driver VR, 2006, OSTOMY WOUND MANAG, V52, P68
   Eguiluz-Ordoñez R, 2006, PLAST RECONSTR SURG, V118, P350, DOI 10.1097/01.prs.0000227666.64552.81
   Fernandez R, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003861.pub3
   Food and Drug Adminstration, 2011, FDA SAF COMM UPD SER, V2012
   FULTON JE, 1995, DERMATOL SURG, V21, P947, DOI 10.1111/j.1524-4725.1995.tb00531.x
   GARCIAVELASCO M, 1978, CAN J SURG, V21, P450
   Gennari R, 2004, SURGERY, V136, P593, DOI 10.1016/j.surg.2004.02.015
   Gethin G, 2008, J Wound Care, V17, P241
   GILMORE OJA, 1977, POSTGRAD MED J, V53, P122, DOI 10.1136/pgmj.53.617.122
   Gir P, 2012, PLAST RECONSTR SURG, V129, P1277, DOI 10.1097/PRS.0b013e31824ecae6
   Glass GE, 2012, J PLAST RECONSTR AES, V65, P989, DOI 10.1016/j.bjps.2011.12.012
   Granick MS, 2006, WOUND REPAIR REGEN, V14, P394, DOI 10.1111/j.1743-6109.2006.00136.x
   Hanazaki K, 2009, WORLD J GASTROENTERO, V15, P4122, DOI 10.3748/wjg.15.4122
   Hassinger SM, 2005, CLIN ORTHOP RELAT R, P27, DOI 10.1097/01.blo.0000182246.37454.b2
   Hayashi T, 2012, DERMATOL SURG, V38, P893, DOI 10.1111/j.1524-4725.2012.02345.x
   INGBER DE, 1989, J CELL BIOL, V109, P317, DOI 10.1083/jcb.109.1.317
   Jäger M, 2009, CURR STEM CELL RES T, V4, P34, DOI 10.2174/157488809787169039
   Javazon EH, 2007, WOUND REPAIR REGEN, V15, P350, DOI 10.1111/j.1524-475X.2007.00237.x
   Kataoka K, 2003, AM J PATHOL, V163, P1227, DOI 10.1016/S0002-9440(10)63482-7
   Khashram M, 2009, J Wound Care, V18, P164
   Khoo TL, 2011, J PLAST RECONSTR AES, V64, pE137, DOI 10.1016/j.bjps.2010.08.029
   Klein MB, 2005, J BURN CARE REHABIL, V26, P483, DOI 10.1097/01.bcr.0000185398.13095.c5
   Kramer S A, 1999, J Vasc Nurs, V17, P17, DOI 10.1016/S1062-0303(99)90004-3
   Kranke P, 2004, ANESTH ANALG, V99, P797, DOI 10.1213/01.ANE.0000133139.68208.92
   Lee DS, 2011, AM J CLIN DERMATOL, V12, P181, DOI 10.2165/11538930-000000000-00000
   LEE LK, 1975, GERIATRICS, V30, P91
   Maeda Yasunori, 2008, Complement Ther Clin Pract, V14, P77, DOI 10.1016/j.ctcp.2007.11.004
   Malmsjö M, 2009, ANN PLAS SURG, V63, P676, DOI 10.1097/SAP.0b013e31819ae01b
   Marcacci M, 2007, TISSUE ENG, V13, P947, DOI 10.1089/ten.2006.0271
   Margolin L, 2010, INT WOUND J, V7, P202, DOI 10.1111/j.1742-481X.2010.00234.x
   Mendonca Derick A, 2006, Int Wound J, V3, P261, DOI 10.1111/j.1742-481X.2006.00266.x
   MILLER JM, 1958, SURGERY, V43, P939
   Moore Z, 2008, J CLIN NURS, V17, P1963, DOI 10.1111/j.1365-2702.2008.02381.x
   Mouës CM, 2008, WOUND REPAIR REGEN, V16, P488, DOI 10.1111/j.1524-475X.2008.00395.x
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   MOUNSEY RA, 1993, LARYNGOSCOPE, V103, P605
   Mustoe TA, 2002, PLAST RECONSTR SURG, V110, P560, DOI 10.1097/00006534-200208000-00031
   Noorani A, 2010, BJS-BRIT J SURG, V97, P1614, DOI 10.1002/bjs.7214
   OSTERBERG B, 1983, ACTA CHIR SCAND, V149, P663
   Pan Q, INVEST OPHTHALMOL VI
   Pietramaggiori G, 2007, ANN SURG, V246, P896, DOI 10.1097/SLA.0b013e3180caa47f
   Quinn J, 1998, ANN EMERG MED, V32, P645, DOI 10.1016/S0196-0644(98)70061-7
   Sainsbury DCG, 2009, INT WOUND J, V6, P24, DOI 10.1111/j.1742-481X.2008.00560.x
   Sanchez EC, 2007, NEUROL RES, V29, P184, DOI 10.1179/016164107X181824
   Saulis AS, 2002, PLAST RECONSTR SURG, V110, P177, DOI 10.1097/00006534-200207000-00029
   Schreml S, 2011, EXP DERMATOL, V20, P229, DOI 10.1111/j.1600-0625.2010.01195.x
   Shake JG, 2002, ANN THORAC SURG, V73, P1919, DOI 10.1016/S0003-4975(02)03517-8
   Shin TM, 2012, DERMATOL SURG, V38, P414, DOI 10.1111/j.1524-4725.2011.02201.x
   Sidle DM, 2011, FACIAL PLAST SURG CL, V19, P505, DOI 10.1016/j.fsc.2011.06.005
   Singer AJ, 1998, ACAD EMERG MED, V5, P94, DOI 10.1111/j.1553-2712.1998.tb02590.x
   Soroff Harry S., 1994, Journal of Burn Care and Rehabilitation, V15, P13, DOI 10.1097/00004630-199401000-00003
   Stadler S, 2011, INTERACT CARDIOV TH, V13, P296, DOI 10.1510/icvts.2011.269001
   Stevenson T R, 1976, JACEP, V5, P17, DOI 10.1016/S0361-1124(76)80160-8
   Tabor OB, 1998, CLIN ORTHOP RELAT R, P117
   Thomas GW, 2009, J TRAUMA, V66, P82, DOI 10.1097/TA.0b013e31818b146d
   Thorn R M S, 2009, J Wound Care, V18, P343
   Van den Kerckhove E, 2005, BURNS, V31, P696, DOI 10.1016/j.burns.2005.04.014
   VARMA AO, 1973, SURG GYNECOL OBSTET, V136, P281
   Vermeulen H, 2010, J HOSP INFECT, V76, P191, DOI 10.1016/j.jhin.2010.04.026
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
   Warnke PH, 2004, LANCET, V364, P766, DOI 10.1016/S0140-6736(04)16935-3
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Wijesinghe M, 2009, NEW ZEAL MED J, V122, P47
   Wollina U, 2000, J EUR ACAD DERMATOL, V14, P285, DOI 10.1046/j.1468-3083.2000.00105.x
   Wongchuensoontorn C, 2009, J CRANIO MAXILL SURG, V37, P155, DOI 10.1016/j.jcms.2008.11.002
   Yi L, 2005, GLIA, V49, P407, DOI 10.1002/glia.20126
NR 93
TC 38
Z9 47
U1 0
U2 14
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD MAR
PY 2014
VL 133
IS 3
BP 383E
EP 392E
DI 10.1097/PRS.0000000000000077
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA AD4TN
UT WOS:000333243600019
PM 24572884
DA 2026-07-24
ER

PT J
AU Kruger, EA
   Pires, M
   Ngann, Y
   Sterling, M
   Rubayi, S
AF Kruger, Erwin A.
   Pires, Marilyn
   Ngann, Yvette
   Sterling, Michelle
   Rubayi, Salah
TI Comprehensive management of pressure ulcers in spinal cord injury:
   Current concepts and future trends
SO JOURNAL OF SPINAL CORD MEDICINE
LA English
DT Review
DE Pressure ulcer; Spinal cord injuries; Wound care; Pressure ulcer
   management
ID VACUUM-ASSISTED CLOSURE; AIR-LOSS BEDS; SURGICAL-MANAGEMENT;
   COST-EFFECTIVENESS; NEGATIVE-PRESSURE; DECUBITUS ULCERS;
   RANDOMIZED-TRIAL; WOUND CONTROL; RISK; PREVENTION
AB Pressure ulcers in spinal cord injury represent a challenging problem for patients, their caregivers, and their physicians. They often lead to recurrent hospitalizations, multiple surgeries, and potentially devastating complications. They present a significant cost to the healthcare system, they require a multidisciplinary team approach to manage well, and outcomes directly depend on patients' education, prevention, and compliance with conservative and surgical protocols. With so many factors involved in the successful treatment of pressure ulcers, an update on their comprehensive management in spinal cord injury is warranted. Current concepts of local wound care, surgical options, as well as future trends from the latest wound healing research are reviewed to aid medical professionals in treating patients with this difficult problem.
C1 [Kruger, Erwin A.; Rubayi, Salah] Rancho Los Amigos Natl Rehabil Ctr, Pressure Ulcer Management Serv, Dept Surg, Downey, CA 90242 USA.
   [Pires, Marilyn; Ngann, Yvette; Sterling, Michelle] Rancho Los Amigos Natl Rehabil Ctr, Dept Nursing, Downey, CA 90242 USA.
RP Rubayi, S (通讯作者)，Rancho Los Amigos Natl Rehabil Ctr, JPI 3140,7601 E Imperial Highway, Downey, CA 90242 USA.
EM srubayi@dhs.lacounty.gov
CR ALLMAN RM, 1987, ANN INTERN MED, V107, P641, DOI 10.7326/0003-4819-107-5-641
   ALLMAN RM, 1989, NEW ENGL J MED, V320, P850
   [Anonymous], 1989, Decubitus, V2, P24
   [Anonymous], COCHRANE DATABASE SY
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Aydin U, 2008, J PLAST RECONSTR AES, V61, P1267, DOI 10.1016/j.bjps.2008.01.024
   Baker Lucinda L., 1996, Wound Repair and Regeneration, V4, P21, DOI 10.1046/j.1524-475X.1996.40106.x
   Bates-Jensen BM, 2008, WOUND REPAIR REGEN, V16, P189, DOI 10.1111/j.1524-475X.2008.00359.x
   Bauer John, 2008, Plast Reconstr Surg, V121, P1, DOI 10.1097/01.prs.0000294671.05159.27
   Black Joyce, 2007, Adv Skin Wound Care, V20, P269, DOI 10.1097/01.ASW.0000269314.23015.e9
   Black JM, 2011, OSTOMY WOUND MANAG, V57, P24
   Brower J, 2011, ADV SKIN WOUND CARE, V24, P524, DOI 10.1097/01.ASW.0000407648.89961.a6
   BRUCK JC, 1991, ANN PLAS SURG, V26, P85, DOI 10.1097/00000637-199101000-00013
   Bryant R.A., 1992, Acute and chronic wounds: nursing management
   CAREY L C, 1962, Surg Forum, V13, P33
   Citak M, 2010, ARCH ORTHOP TRAUM SU, V130, P1511, DOI 10.1007/s00402-010-1091-6
   Clark FA, 2006, ARCH PHYS MED REHAB, V87, P1516, DOI 10.1016/j.apmr.2006.08.329
   Daniel R K, 1979, Ann Plast Surg, V3, P53
   DANIEL RK, 1982, ANN PLAS SURG, V8, P446, DOI 10.1097/00000637-198206000-00002
   DINSDALE SM, 1974, ARCH PHYS MED REHAB, V55, P147
   DINSDALE SM, 1973, ARCH PHYS MED REHAB, V54, P51
   Dorner B, 2009, ADV SKIN WOUND CARE, V22, P212, DOI 10.1097/01.ASW.0000350838.11854.0a
   Evans D, 2001, BRIT J PLAST SURG, V54, P238, DOI 10.1054/bjps.2001.3547
   Evers L, 2009, J PLAST RECONSTR AES, V62, p831S
   Fan K, 2011, PLAST RECONSTR SURG, V127, p44S, DOI 10.1097/PRS.0b013e3181fbe275
   FERRELL BA, 1993, JAMA-J AM MED ASSOC, V269, P494, DOI 10.1001/jama.269.4.494
   FERRELL BA, 1995, J GERONTOL A-BIOL, V50, pM141, DOI 10.1093/gerona/50A.3.M141
   Ford CN, 2002, ANN PLAS SURG, V49, P55, DOI 10.1097/00000637-200207000-00009
   FUHRER MJ, 1993, ARCH PHYS MED REHAB, V74, P1172
   Garber SL, 1996, ARCH PHYS MED REHAB, V77, P744, DOI 10.1016/S0003-9993(96)90251-8
   Garber SL, 2000, ARCH PHYS MED REHAB, V81, P465, DOI 10.1053/mr.2000.3889
   Sarasúa JG, 2011, J SPINAL CORD MED, V34, P301, DOI 10.1179/2045772311Y.0000000010
   Griffin M, 2011, PLOS ONE, V6, DOI 10.1371/journal.pone.0023404
   GROTH KE, 1942, ACTA CHIRURG SCANDIN, V87, P207
   Gupta Subhas, 2004, Adv Skin Wound Care, V17 Suppl 2, P1, DOI 10.1097/00129334-200411002-00001
   Gurtner GC, 2008, NATURE, V453, P314, DOI 10.1038/nature07039
   HEGGERS J P, 1991, Journal of Burn Care and Rehabilitation, V12, P420, DOI 10.1097/00004630-199109000-00005
   HUSAIN T, 1953, J PATHOL BACTERIOL, V66, P347, DOI 10.1002/path.1700660203
   INMAN KJ, 1993, JAMA-J AM MED ASSOC, V269, P1139
   Jackson J, 2010, DISABIL REHABIL, V32, P567, DOI 10.3109/09638280903183829
   Janis J.E., 2003, SELECTED READINGS PL, V9, P1
   Kavalukas SL, 2011, PLAST RECONSTR SURG, V127, p38S, DOI 10.1097/PRS.0b013e318201256c
   KEANE FX, 1979, PARAPLEGIA, V16, P383, DOI 10.1038/sc.1978.72
   KEANE FX, 1979, PARAPLEGIA, V16, P390, DOI 10.1038/sc.1978.73
   Ko SH, 2011, PLAST RECONSTR SURG, V127, p10S, DOI 10.1097/PRS.0b013e3181fbe2d8
   Kosiak M, 1991, Decubitus, V4, P60
   KOSIAK M, 1961, Arch Phys Med Rehabil, V42, P19
   KOSIAK M, 1958, Arch Phys Med Rehabil, V39, P623
   Landis EM, 1933, J CLIN INVEST, V12, P105, DOI 10.1172/JCI100482
   Landis EM, 1930, HEART-J STUD CIRC, V15, P209
   Leclercq R, 2009, CLIN MICROBIOL INFEC, V15, P224, DOI 10.1111/j.1469-0691.2009.02739.x
   LEE JJ, 1988, KOREAN J CHEM ENG, V5, P5, DOI 10.1007/BF02697470
   Levine J. M., 2008, Clinical Geriatrics, V16, P19
   Levine SM, 2012, ANN PLAS SURG, V69, P482, DOI 10.1097/SAP.0b013e31824b26bc
   LEWIS VL, 1988, PLAST RECONSTR SURG, V81, P229, DOI 10.1097/00006534-198802000-00016
   Li Y, 2011, JAMA-J AM MED ASSOC, V306, P179, DOI 10.1001/jama.2011.942
   Makhsous M, 2007, J SPINAL CORD MED, V30, P497, DOI 10.1080/10790268.2007.11754584
   Marriott R, 2008, ANN PLAS SURG, V61, P425, DOI 10.1097/SAP.0b013e318162f257
   Montgomerie JZ, 1997, CLIN INFECT DIS, V25, P1285, DOI 10.1086/516144
   Morton SC, 2002, ARCH PHYS MED REHAB, V83, P129, DOI 10.1053/apmr.2002.26605
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Nakamura K, 1999, NUTRITION, V15, P834, DOI 10.1016/S0899-9007(99)00176-8
   Orgill DP, 2011, PLAST RECONSTR SURG, V127, p105S, DOI 10.1097/PRS.0b013e318200a427
   Rees RS, 1999, WOUND REPAIR REGEN, V7, P141, DOI 10.1046/j.1524-475X.1999.00141.x
   Regan MA, 2009, ARCH PHYS MED REHAB, V90, P213, DOI 10.1016/j.apmr.2008.08.212
   REULER JB, 1981, ANN INTERN MED, V94, P661, DOI 10.7326/0003-4819-94-5-661
   Rosenthal MB, 2007, NEW ENGL J MED, V357, P1573, DOI 10.1056/NEJMp078184
   Rubayi S, 1990, AORN J, V52, P40, DOI 10.1016/S0001-2092(07)67284-6
   Rubayi S, 1999, ANN PLAS SURG, V42, P533, DOI 10.1097/00000637-199905000-00012
   RUBAYI S, 1991, ANN PLAS SURG, V27, P132, DOI 10.1097/00000637-199108000-00007
   Rubayi S, 2011, PLAST RECONSTR SURG, V128, p201E, DOI 10.1097/PRS.0b013e31822214c1
   Salcido R., PRESSURE ULCERS WOUN
   Sameem M, 2012, PLAST RECONSTR SURG, V130, p67E, DOI 10.1097/PRS.0b013e318254b19f
   Saunders LL, 2010, J SPINAL CORD MED, V33, P387, DOI 10.1080/10790268.2010.11689717
   Scivoletto G, 2004, SPINAL CORD, V42, P473, DOI 10.1038/sj.sc.3101622
   Scott-Williams S., 2009, OUTPATIENT SURG MAGA, V10
   Tchanque-Fossuo CN, 2011, PLAST RECONSTR SURG, V127, P932, DOI 10.1097/PRS.0b013e3182046a02
   Zhao Zhiqiang, 2011, Eur Cell Mater, V22, P344
NR 79
TC 165
Z9 205
U1 0
U2 35
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND
SN 1079-0268
EI 2045-7723
J9 J SPINAL CORD MED
JI J. Spinal Cord. Med.
PD NOV
PY 2013
VL 36
IS 6
BP 572
EP 585
DI 10.1179/2045772313Y.0000000093
PG 14
WC Clinical Neurology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology
GA 264JC
UT WOS:000327871900002
PM 24090179
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Liu, XX
   Kaminsky, AJ
   Hill, DM
   Velamuri, SR
AF Liu, Xiangxia
   Kaminsky, Alexander J.
   Hill, David M.
   Velamuri, Sai R.
TI Heterotopic ossification: a preventable case of gossypiboma in spinal
   cord injury
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE heterotopic ossification; gossypiboma; negative wound pressure therapy;
   spinal cord injury
ID RISK-FACTORS; ASSOCIATION; RADIOTHERAPY; RADIATION; SPONGE; BONE
AB Objective: Heterotopic ossification is the formation of ectopic bone in soft tissues. It has three established aetiologies: genetic, traumatic and neurogenic. A gossypiboma is defined as a retained foreign body, such as a mass or sponge, usually after a surgical procedure. In this article, we present a unique, preventable case of a patient admitted for newly developed heterotopic ossification in the gluteus maximus muscle caused by a retained piece of foam from negative pressure wound therapy (NPWT). The heterotopic ossification lesion, together with the retained foreign body, was completely excised and reconstructed using a posterior thigh fasciocutaneous advancement flap. This is the first reported case of heterotopic ossification caused by a retained foreign body and may be helpful to better understanding of the aetiology of heterotopic ossification.
C1 [Liu, Xiangxia; Kaminsky, Alexander J.; Velamuri, Sai R.] Univ Tennessee, Ctr Hlth Sci, Dept Plast Surg, Memphis, TN 38163 USA.
   [Liu, Xiangxia] Sun Yat Sen Univ, Affiliated Hosp 1, Div Plast Surg, Guangzhou, Peoples R China.
   [Hill, David M.] Firefighters Burn Ctr, Dept Pharm, Reg One Hlth, Memphis, TN USA.
   [Hill, David M.] Univ Tennessee, Ctr Hlth Sci, Dept Clin Pharm, Coll Pharm, Memphis, TN 38163 USA.
C3 University of Tennessee System; University of Tennessee Health Science
   Center; Sun Yat Sen University; University of Tennessee System;
   University of Tennessee Health Science Center
RP Kaminsky, AJ (通讯作者)，Univ Tennessee, Ctr Hlth Sci, Dept Plast Surg, Memphis, TN 38163 USA.
EM alexkaminsky@gmail.com
RI /AAI-2609-2019
OI Hill, David/0000-0002-1119-1901
CR Ahmed F, 2010, J PLAST RECONSTR AES, V63, pE497, DOI 10.1016/j.bjps.2009.09.006
   Balboni TA, 2006, INT J RADIAT ONCOL, V65, P1289, DOI 10.1016/j.ijrobp.2006.03.053
   Banovac K, 2004, SPINAL CORD, V42, P707, DOI 10.1038/sj.sc.3101628
   Banovac K, 2001, SPINAL CORD, V39, P370, DOI 10.1038/sj.sc.3101166
   Brown KV, 2010, J TRAUMA, V69, pS116, DOI 10.1097/TA.0b013e3181e44cc7
   Citak M, 2011, Z ORTHOP UNFALLCHIR, V149, P90, DOI 10.1055/s-0030-1250688
   Citak M, 2012, SPINE, V37, P1953, DOI 10.1097/BRS.0b013e31825ee81b
   Coelho CVC, 2009, ARQ NEURO-PSIQUIAT, V67, P382, DOI 10.1590/S0004-282X2009000300002
   COVENTRY MB, 1981, J BONE JOINT SURG AM, V63, P201, DOI 10.2106/00004623-198163020-00004
   Dong LW, 2017, MED SCI MONITOR, V23, P5382, DOI 10.12659/MSM.904626
   Evans KN, 2012, J ORTHOP TRAUMA, V26, pE204, DOI 10.1097/BOT.0b013e31825d60a5
   Fox A, 2004, J Wound Care, V13, P344
   Genêt F, 2015, SPINAL CORD, V53, P340, DOI 10.1038/sc.2015.20
   Hallock GG, 2008, PLAST RECONSTR SURG, V122, p84E, DOI 10.1097/PRS.0b013e31817d6528
   Hunt JL, 2006, J BURN CARE RES, V27, P535, DOI 10.1097/01.BCR.0000226023.58438.14
   Maier D, 2005, ORTHOPADE, V34, P120, DOI 10.1007/s00132-004-0754-9
   Mazoch M, 2015, J WOUND CARE, V24, pS18, DOI 10.12968/jowc.2015.24.Sup6.S18
   McCarthy EF, 2005, SKELETAL RADIOL, V34, P609, DOI 10.1007/s00256-005-0958-z
   Milakovic M, 2015, RADIOTHER ONCOL, V116, P4, DOI 10.1016/j.radonc.2015.05.022
   Naraghi FF, 1996, ORTHOPEDICS, V19, P145
   Ohlmeier M, 2017, SPINE J, V17, P1519, DOI 10.1016/j.spinee.2017.04.021
   Oleson CV, 2013, J REHABIL RES DEV, V50, P1177, DOI 10.1682/JRRD.2012.11.0206
   Ploumis A, 2015, J SPINAL CORD MED, V38, P193, DOI 10.1179/2045772314Y.0000000213
   Ranganathan K, 2015, J BONE JOINT SURG AM, V97A, P1101, DOI 10.2106/JBJS.N.01056
   Rencuzogullari A, 2015, INT WOUND J, V12, P739, DOI 10.1111/iwj.12200
   Rosteius T, 2017, SPINAL CORD, V55, P71, DOI 10.1038/sc.2016.93
   Sakellariou VI, 2012, J MUSCULOSKEL NEURON, V12, P230
   Teasell RW, 2010, SPINAL CORD, V48, P512, DOI 10.1038/sc.2009.175
   van Kuijk AA, 2002, SPINAL CORD, V40, P313, DOI 10.1038/sj.sc.3101309
   Yang K, 2017, J PLAST RECONSTR AES, V70, P518, DOI 10.1016/j.bjps.2016.11.026
   Zhang RR, 2013, BONE, V52, P145, DOI 10.1016/j.bone.2012.09.029
NR 31
TC 1
Z9 1
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD MAR 2
PY 2020
VL 29
IS 3
SU 3
BP S30
EP S32
DI 10.12968/jowc.2020.29.Sup3.S30
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA KU7LR
UT WOS:000519895100005
PM 32160126
DA 2026-07-24
ER

PT J
AU Xu, CZ
   Zhou, WJ
   Zou, XD
   Dong, YZ
   Alhaskawi, A
   Zhou, HY
   Lu, H
AF Xu, Chuze
   Zhou, Weijie
   Zou, Xiaodi
   Dong, Yanzhao
   Alhaskawi, Ahmad
   Zhou, Haiying
   Lu, Hui
TI Case Report on Necrotizing Fasciitis after Liposuction and
   Abdominoplasty
SO JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
LA English
DT Article
DE jove.com/video/69043
ID LABORATORY RISK INDICATOR; COMPLICATION RATES; SURGERY; SAFETY;
   MANAGEMENT; DIAGNOSIS; SCORE; SKIN; TOOL
AB Liposuction and abdominoplasty are common cosmetic procedures, but they can lead to severe complications such as necrotizing fasciitis (NF), which is a life-threatening infection with rapid progression and significant mortality rates. NF can develop after surgical procedures due to bacterial colonization or inadequate postoperative care. In the case shown here, a 33-year-old woman presented with skin flap fascial necrosis with abdominal wall infection 20 days after undergoing abdominoplasty with liposuction at another private clinic. Initial management included incision and drainage of an abdominal wall sinus tract, debridement of necrotic tissue, and application of antibiotic bone cement, followed by vacuum sealing drainage (VSD). Postoperative blood tests and bacterial culture identified multiple pathogens, all susceptible to quinolones. Subsequent surgeries involved re-debridement and skin grafting. The patient received a comprehensive rehabilitation program, resulting in effective infection control and favorable outcomes. The case underscores the importance of early diagnosis and aggressive surgical debridement in managing NF. The use of antibiotic bone cement provided local high-concentration antibiotics and supported granulation tissue formation, contributing to the treatment of the wound. This rare complication highlights the potential risks of cosmetic surgery and the necessity of strict adherence to aseptic techniques.
C1 [Xu, Chuze] Wenzhou Med Univ, Sch Optometry & Ophthalmol, Wenzhou, Peoples R China.
   [Xu, Chuze; Zhou, Weijie; Zou, Xiaodi; Dong, Yanzhao; Alhaskawi, Ahmad; Zhou, Haiying; Lu, Hui] Zhejiang Univ, Affiliated Hosp 1, Dept Orthoped, Hangzhou, Peoples R China.
C3 Wenzhou Medical University; Zhejiang University
RP Lu, H (通讯作者)，Zhejiang Univ, Affiliated Hosp 1, Dept Orthoped, Hangzhou, Peoples R China.
EM huilu@zju.edu.cn
RI ; Dong, Yanzhao/KAM-2859-2024
OI lu, hui/0000-0002-5921-1043; 
CR Bilton BD, 1998, AM SURGEON, V64, P397
   Chen Leon L, 2020, Nursing, V50, P34, DOI 10.1097/01.NURSE.0000694752.85118.62
   Comerci AJ, 2024, AESTHET SURG J, V44, pNP454, DOI 10.1093/asj/sjae074
   Dong YZ, 2024, BMC INFECT DIS, V24, DOI 10.1186/s12879-024-09336-7
   Ehya REM, 2021, J DIABETES RES, V2021, DOI 10.1155/2021/9911072
   Ezzeddine H, 2018, AESTHET PLAST SURG, V42, P384, DOI 10.1007/s00266-017-1058-x
   Gilardi R, 2023, JPRAS OPEN, V38, P129, DOI 10.1016/j.jpra.2023.10.004
   Gilardi R, 2023, J PLAST RECONSTR AES, V84, P9, DOI 10.1016/j.bjps.2023.05.021
   Goh T, 2014, BJS-BRIT J SURG, V101, pE119, DOI 10.1002/bjs.9371
   Gonzales Alana I, 2007, Acta Chir Plast, V49, P99
   Grazer FM, 2000, PLAST RECONSTR SURG, V105, P436, DOI 10.1097/00006534-200001000-00070
   Gu W, 2019, ANNU REV PATHOL-MECH, V14, P319, DOI 10.1146/annurev-pathmechdis-012418-012751
   Hefny AF, 2007, EUR J EMERG MED, V14, P50, DOI 10.1097/01.mej.0000228447.48276.7b
   Kaoutzanis C, 2017, AESTHET SURG J, V37, P680, DOI 10.1093/asj/sjw243
   Kim YH, 2011, PLAST RECONSTR SURG, V127, P863, DOI 10.1097/PRS.0b013e318200afbf
   Langelier C, 2018, P NATL ACAD SCI USA, V115, pE12353, DOI 10.1073/pnas.1809700115
   Lehnhardt Marcus, 2008, Plast Reconstr Surg, V121, p396e, DOI 10.1097/PRS.0b013e318170817a
   Li K, 2024, INFECT DRUG RESIST, V17, P1003, DOI 10.2147/IDR.S445366
   Lin H, 2024, J ORTHOP SURG RES, V19, DOI 10.1186/s13018-024-05143-7
   Liu ZW, 2021, BMC INFECT DIS, V21, DOI 10.1186/s12879-021-06777-2
   Lu JQ, 2022, BMC INFECT DIS, V22, DOI 10.1186/s12879-022-07574-1
   Marchesi A, 2017, AESTHET PLAST SURG, V41, P352, DOI 10.1007/s00266-016-0754-2
   Miller S, 2022, CLIN CHEM, V68, P115, DOI 10.1093/clinchem/hvab173
   Misiakos EP, 2014, FRONT SURG, V1, DOI 10.3389/fsurg.2014.00036
   Moskowitz E., 2018, Trauma Surg Acute Care Open
   Moyes Rita B, 2009, Curr Protoc Microbiol, VAppendix 3, p3C, DOI 10.1002/9780471729259.mca03cs15
   Neeki MM, 2017, WEST J EMERG MED, V18, P684, DOI 10.5811/westjem.2017.3.33607
   Pelosi M. A., 2010, Obstet Gynecol Clin North Am., V37, pviii
   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
   Sharma D, 2006, AESTHET PLAST SURG, V30, P712, DOI 10.1007/s00266-006-0078-8
   Sherman JE, 2010, PLAST RECONSTR SURG, V126, P1358, DOI 10.1097/PRS.0b013e3181ea4576
   Shimizu T, 2010, INTERNAL MED, V49, P1051, DOI 10.2169/internalmedicine.49.2964
   Shiroff AM, 2014, J INTENSIVE CARE MED, V29, P138, DOI 10.1177/0885066612463680
   Simner PJ, 2018, CLIN INFECT DIS, V66, P778, DOI 10.1093/cid/cix881
   Stephan PJ, 2010, AESTHET SURG J, V30, P83, DOI 10.1177/1090820X10362728
   Stevens DL, 2017, NEW ENGL J MED, V377, P2253, DOI 10.1056/NEJMra1600673
   Stevens DL, 2014, CLIN INFECT DIS, V59, pE10, DOI [10.1093/cid/ciu296, 10.1093/cid/ciu444]
   Theocharidis V, 2018, J PLAST RECONSTR AES, V71, P624, DOI 10.1016/j.bjps.2018.01.011
   Thomas AJ, 2012, LARYNGOSCOPE, V122, P2683, DOI 10.1002/lary.23680
   Verfaillie G, 2002, Eur J Emerg Med, V9, P270, DOI 10.1097/00063110-200209000-00013
   VOROS D, 1993, BRIT J SURG, V80, P1190, DOI 10.1002/bjs.1800800943
   Wang JM, 2014, BRAZ J INFECT DIS, V18, P137
   WILSON B, 1952, Am Surg, V18, P416
   Wilson MP, 2013, J EMERG MED, V44, P928, DOI 10.1016/j.jemermed.2012.09.039
   Winocour J, 2015, PLAST RECONSTR SURG, V136, p597E, DOI 10.1097/PRS.0000000000001700
   Wong CH, 2004, CRIT CARE MED, V32, P1535, DOI 10.1097/01.CCM.0000129486.35458.7D
   Wu S, 2020, CLEV CLIN J MED, V87, P367, DOI 10.3949/ccjm.87a.19097
   You JS, 2015, KOREAN J RADIOL, V16, P1197
   Zhang MJ, 2020, J INT MED RES, V48, DOI 10.1177/0300060520937623
NR 49
TC 0
Z9 0
U1 1
U2 5
PU JOURNAL OF VISUALIZED EXPERIMENTS
PI CAMBRIDGE
PA 1 ALEWIFE CENTER, STE 200, CAMBRIDGE, MA 02140 USA
SN 1940-087X
J9 JOVE-J VIS EXP
JI J. Vis. Exp.
PD OCT
PY 2025
IS 224
AR e69043
DI 10.3791/69043
PG 18
WC Multidisciplinary Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Science & Technology - Other Topics
GA 9WL1P
UT WOS:001616653700005
PM 41115143
DA 2026-07-24
ER

PT J
AU Yang, L
   Guo, JC
   He, JP
   Shao, JF
AF Yang, Liu
   Guo, Jiachao
   He, Jinpeng
   Shao, Jingfan
TI Skin grafting treatment of adolescent lower limb avulsion injury
SO FRONTIERS IN SURGERY
LA English
DT Review
DE adolescent; avulsion; skin graft; NPWT; SCAR
ID PRESSURE WOUND THERAPY; VACUUM SEALING DRAINAGE; DERMAL REGENERATION
   TEMPLATE; MINIMALLY INVASIVE TOOL; LOWER LEG DEFECTS; OPEN CELL FOAM;
   FULL-THICKNESS; ARTIFICIAL DERMIS; BED PREPARATION; CLINICAL-EVALUATION
AB Background: Under the influence of various factors, the number of lower extremity avulsion injuries in adolescents is increasing year by year. The main modality of treatment is skin grafting. There are many types of skin grafting. Although many studies on skin grafting after avulsion injuries have been published in the past few decades, there are differences in the treatment options for adolescents with post avulsion injuries. Main body: Thorough debridement and appropriate skin grafts are essential for the surgical management of avulsion injuries for optimal prognosis. In the acquisition of grafts, progress has been made in equipment for how to obtain different depths of skin. The severity of the avulsion injury varies among patients on admission, and therefore the manner and type of skin grafting will vary. Especially in adolescents, graft survival and functional recovery are of great concern to both patients and physicians. Therefore, many efforts have been made to improve survival rate and activity. Conclusion: This review summarizes the principles of treatment of avulsion injuries, the historical development of skin grafts, and the selection of skin grafts, hoping to be helpful for future research.
C1 [Yang, Liu; Guo, Jiachao; He, Jinpeng; Shao, Jingfan] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Pediat Surg, Wuhan, Peoples R China.
C3 Huazhong University of Science & Technology
RP Shao, JF (通讯作者)，Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Pediat Surg, Wuhan, Peoples R China.
EM shaojf65@126.com
RI He, Jinpeng/GQI-2034-2022
CR Achora S, 2014, J WOUND OSTOMY CONT, V41, P335, DOI 10.1097/WON.0000000000000035
   Adams DC, 2005, DERMATOL SURG, V31, P1055
   Akita S, 2010, WOUND REPAIR REGEN, V18, P560, DOI 10.1111/j.1524-475X.2010.00620.x
   Al-Mutairi N, 2010, DERMATOL SURG, V36, P499, DOI 10.1111/j.1524-4725.2010.01477.x
   Ameer Faisal, 2013, Indian J Plast Surg, V46, P28, DOI 10.4103/0970-0358.113704
   Andreassi A, 2005, CLIN DERMATOL, V23, P332, DOI 10.1016/j.clindermatol.2004.07.024
   Anglen J O, 2001, J Am Acad Orthop Surg, V9, P219
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Attia A, 2020, JPRAS OPEN, V24, P32, DOI 10.1016/j.jpra.2020.03.004
   Audrain H, 2015, DERMATOL SURG, V41, P493, DOI 10.1097/DSS.0000000000000330
   Benny P, 2015, TISSUE ENG PT A, V21, P183, DOI [10.1089/ten.tea.2013.0784, 10.1089/ten.TEA.2013.0784]
   Bhandari M, 2015, NEW ENGL J MED, V373, P2629, DOI 10.1056/NEJMoa1508502
   BILLINGHAM RE, 1955, J ANAT, V89, P114
   BODENHAM D C, 1971, British Journal of Plastic Surgery, V24, P20, DOI 10.1016/S0007-1226(71)80005-X
   BODENHAM DC, 1949, BRIT J PLAST SURG, V2, P136
   Boettcher-Haberzeth S, 2013, EUR J PEDIATR SURG, V23, P359, DOI 10.1055/s-0033-1353493
   BRANHAM GH, 1990, OTOLARYNG CLIN N AM, V23, P889
   Browne S, 2019, ADV DRUG DELIVER REV, V146, P155, DOI 10.1016/j.addr.2018.12.016
   Cass DL, 1997, PEDIATR SURG INT, V12, P484, DOI 10.1007/s003830050189
   Chandrasegaram MD, 2009, J BURN CARE RES, V30, P867, DOI 10.1097/BCR.0b013e3181b48610
   Chang LK, 2001, DERMATOL SURG, V27, P759, DOI 10.1046/j.1524-4725.2001.01089.x
   Chatterjee R, 2021, MIL MED, V186, P364, DOI 10.1093/milmed/usaa276
   Chen TM, 2010, DERMATOL SURG, V36, P453, DOI 10.1111/j.1524-4725.2010.01480.x
   Chen Y, 2016, CHIN J TRAUMATOL, V19, P337, DOI 10.1016/j.cjtee.2016.09.003
   Chern PL, 2009, DERMATOL SURG, V35, P891, DOI 10.1111/j.1524-4725.2009.01153.x
   Chouhan D, 2020, ACTA BIOMATER, V103, P24, DOI 10.1016/j.actbio.2019.11.050
   Cobbett J, 1968, Br J Plast Surg, V21, P216, DOI 10.1016/S0007-1226(68)80017-7
   Coentro JQ, 2019, ADV DRUG DELIVER REV, V146, P37, DOI 10.1016/j.addr.2018.08.009
   Contractor D, 2008, J ORTHOP TRAUMA, V22, pS167, DOI 10.1097/BOT.0b013e318188e295
   Corps B V, 1969, Br J Plast Surg, V22, P125, DOI 10.1016/S0007-1226(69)80053-6
   Dai CT, 2020, J DERMATOL TREAT, V31, P639, DOI 10.1080/09546634.2018.1530443
   DAVIES DM, 1985, BMJ-BRIT MED J, V290, P1056, DOI 10.1136/bmj.290.6474.1056
   Davis J S, 1941, Ann Surg, V113, P641, DOI 10.1097/00000658-194105000-00001
   DEITCH EA, 1983, J TRAUMA, V23, P895, DOI 10.1097/00005373-198310000-00009
   Dunkin CSJ, 2007, PLAST RECONSTR SURG, V119, P1722, DOI 10.1097/01.prs.0000258829.07399.f0
   Eldenburg E, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9247
   Falanga V, 2000, WOUND REPAIR REGEN, V8, P347
   Farrar JJ, 2000, J NEUROL NEUROSUR PS, V69, P292, DOI 10.1136/jnnp.69.3.292
   FIELD LM, 1980, J DERMATOL SURG ONC, V6, P690
   Finnerty CC, 2016, LANCET, V388, P1427, DOI 10.1016/S0140-6736(16)31406-4
   Foote CJ, 2015, CLIN ORTHOP RELAT R, V473, P2179, DOI 10.1007/s11999-015-4224-y
   Gabriel Allen, 2014, Surg Technol Int, V25, P55
   GLOGAU RG, 1987, J DERMATOL SURG ONC, V13, P853, DOI 10.1111/j.1524-4725.1987.tb00562.x
   GOLDMINZ D, 1991, ARCH DERMATOL, V127, P1012, DOI 10.1001/archderm.127.7.1012
   Greaves NS, 2015, WOUND REPAIR REGEN, V23, P483, DOI 10.1111/wrr.12308
   Gronovich Y, 2016, BURNS TRAUMA, V4, DOI 10.1186/s41038-016-0037-9
   Gupta S, 2012, INT WOUND J, V9, P40, DOI 10.1111/j.1742-481X.2012.01019.x
   Hachach-Haram N, 2017, INT WOUND J, V14, P241, DOI 10.1111/iwj.12595
   Hachach-Haram N, 2015, J PLAST RECONSTR AES, V68, P1317, DOI 10.1016/j.bjps.2015.04.019
   Halim AS, 2010, INDIAN J PLAST SURG, V43, pS23, DOI 10.4103/0970-0358.70712
   Han T, 2012, J CRANIOFAC SURG, V23, P439, DOI 10.1097/SCS.0b013e318231964a
   Hanafusa T, 2008, J DERMATOL SCI, V50, P243, DOI 10.1016/j.jdermsci.2008.02.001
   Harries RL, 2016, INT WOUND J, V13, P8, DOI 10.1111/iwj.12662
   Harrison CA, 2008, BURNS, V34, P153, DOI 10.1016/j.burns.2007.08.011
   Harvey I, 2009, J PLAST RECONSTR AES, V62, P969, DOI 10.1016/j.bjps.2007.10.082
   Haslik W, 2010, J PLAST RECONSTR AES, V63, P360, DOI 10.1016/j.bjps.2008.09.026
   Heimbach DM, 2003, J BURN CARE REHABIL, V24, P42, DOI 10.1097/00004630-200301000-00009
   HENTZER B, 1975, ACTA DERM-VENEREOL, V55, P207
   Herskovitz I, 2016, INT WOUND J, V13, P52, DOI 10.1111/iwj.12631
   HINSHAW JR, 1965, ARCH SURG-CHICAGO, V91, P658
   Holzer PW, 2017, J BURN CARE RES, V38, pE55, DOI 10.1097/BCR.0000000000000431
   Hospenthal DR, 2011, J TRAUMA, V71, pS210, DOI 10.1097/TA.0b013e318227ac4b
   Huang Q, 2019, J FOOT ANKLE SURG, V58, P954, DOI 10.1053/j.jfas.2018.12.020
   Hudson DA, 2015, INT WOUND J, V12, P195, DOI 10.1111/iwj.12080
   JOHNSON TM, 1992, J AM ACAD DERMATOL, V27, P151, DOI 10.1016/0190-9622(92)70164-B
   Kalisman M, 1978, J Dermatol Surg Oncol, V4, P322
   Kanapathy M, 2017, INT WOUND J, V14, P921, DOI 10.1111/iwj.12729
   Kanapathy M, 2017, INT WOUND J, V14, P16, DOI 10.1111/iwj.12686
   Kanapathy M, 2016, SYST REV-LONDON, V5, DOI 10.1186/s13643-016-0268-7
   Keating AM, 2011, OCUL SURF, V9, P227, DOI 10.1016/S1542-0124(11)70035-0
   Kheirabadi BS, 2012, J TRAUMA ACUTE CARE, V73, P1188, DOI 10.1097/TA.0b013e31826f98ea
   KIISTALA U, 1964, LANCET, V1, P1444
   KIISTALA U, 1967, J INVEST DERMATOL, V48, P466, DOI 10.1038/jid.1967.72
   Kim HS, 2019, ADV DRUG DELIVER REV, V146, P209, DOI 10.1016/j.addr.2018.12.014
   Lee JW, 2005, ANN PLAS SURG, V55, P500, DOI 10.1097/01.sap.0000183789.00146.c6
   Lerman Bruce, 2010, J Diabetes Sci Technol, V4, P825
   Levinson H, 2013, ADV WOUND CARE, V2, P149, DOI 10.1089/wound.2012.0389
   Li ZQ, 2017, INT J SURG, V42, P143, DOI 10.1016/j.ijsu.2017.04.059
   Liew S, 2001, ANN PLAS SURG, V47, P608, DOI 10.1097/00000637-200112000-00004
   Luczak B, 2012, AUSTRALAS J DERMATOL, V53, P19, DOI 10.1111/j.1440-0960.2011.00829.x
   Lv ZM, 2020, J INVEST SURG, V33, P636, DOI 10.1080/08941939.2018.1536177
   Lv ZM, 2019, MEDICINE, V98, DOI 10.1097/MD.0000000000015864
   Mathew A, 2021, SAUDI J ANAESTH, V15, P435, DOI 10.4103/sja.sja_140_21
   Matsumura H, 2016, BURNS, V42, P769, DOI 10.1016/j.burns.2016.01.019
   McCallon Stanley K, 2014, J Am Coll Clin Wound Spec, V6, P14, DOI 10.1016/j.jccw.2015.08.003
   MCGREGOR IA, 1978, HEAD NECK SURG, V1, P47, DOI 10.1002/hed.2890010107
   Moreci RS, 2020, CURR BIOL, V30, pR144, DOI 10.1016/j.cub.2020.01.004
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Nagama T, 2020, J SURG CASE REP, DOI 10.1093/jscr/rjaa498
   NAPIER JR, 1952, BRAIN, V75, P147, DOI 10.1093/brain/75.2.147
   Nathoo Rajiv, 2014, J Clin Aesthet Dermatol, V7, P44
   Oganesyan G, 2013, DERMATOL SURG, V39, P1334, DOI 10.1111/dsu.12254
   Osborne SN, 2016, ADV SKIN WOUND CARE, V29, P57, DOI 10.1097/01.ASW.0000476072.88818.aa
   Osborne SN, 2015, ADV SKIN WOUND CARE, V28, P397, DOI 10.1097/01.ASW.0000470024.81711.b8
   Patterson I, 2006, PLAST RECONSTR SURG, V118, P1551, DOI 10.1097/01.prs.0000240809.75586.be
   Pitkanen JM, 2000, ANN PLAS SURG, V45, P118, DOI 10.1097/00000637-200045020-00003
   POPE ER, 1990, VET CLIN N AM-SMALL, V20, P177, DOI 10.1016/S0195-5616(90)50009-1
   Pratsinis H, 2019, ADV DRUG DELIVER REV, V146, P325, DOI 10.1016/j.addr.2018.04.011
   Priya SG, 2008, TISSUE ENG PART B-RE, V14, P105, DOI 10.1089/teb.2007.0318
   Puetzler J, 2019, INJURY, V50, P1208, DOI 10.1016/j.injury.2019.04.013
   Qu JF, 2013, EXP THER MED, V5, P1375, DOI 10.3892/etm.2013.999
   Rao Krishna, 2008, Dermatol Online J, V14, P4
   Ren YH, 2021, J INVEST SURG, V34, P344, DOI 10.1080/08941939.2019.1625986
   Robert N, 2017, ORTHOP TRAUMATOL-SUR, V103, pS99, DOI 10.1016/j.otsr.2016.04.018
   Robinson JK, 2002, DERMATOL SURG, V28, P845, DOI 10.1046/j.1524-4725.2002.02031.x
   Rousselle P, 2019, ADV DRUG DELIVER REV, V146, P344, DOI 10.1016/j.addr.2018.06.019
   Rowe NM, 2006, ANN PLAS SURG, V57, P305, DOI 10.1097/01.sap.0000221622.41450.60
   Rudolph R, 1980, World J Surg, V4, P279
   Sakai G, 2017, INJURY, V48, P137, DOI 10.1016/j.injury.2016.10.026
   Sakamoto M, 2017, ANN PLAS SURG, V78, P651, DOI 10.1097/SAP.0000000000001058
   Schade Valerie L, 2008, Foot Ankle Spec, V1, P155, DOI 10.1177/1938640008317782
   Schalper KA, 2012, MOL BIOSYST, V8, P685, DOI 10.1039/c1mb05294b
   Schiestl C, 2011, EUR J PEDIATR SURG, V21, P106, DOI 10.1055/s-0030-1267234
   Schiller J, 2017, J AM ACAD ORTHOP SUR, V25, P251, DOI 10.5435/JAAOS-D-15-00328
   Schlatterer D, 2008, J ORTHOP TRAUMA, V22, pS152, DOI 10.1097/BOT.0b013e318188e2d7
   Schultz Gregory S, 2004, Int Wound J, V1, P19, DOI 10.1111/j.1742-481x.2004.00008.x
   Schultz GS, 2003, WOUND REPAIR REGEN, V11, pS1, DOI 10.1046/j.1524-475X.11.s2.1.x
   Semerano L, 2016, ANGIOGENESIS, V19, P39, DOI 10.1007/s10456-015-9487-0
   Serena T, 2015, ADV SKIN WOUND CARE, V28, P107, DOI 10.1097/01.ASW.0000460839.72826.ce
   SHARPE DT, 1983, BRIT J PLAST SURG, V36, P105, DOI 10.1016/0007-1226(83)90024-3
   Smith OJ, 2017, INT WOUND J, V14, P555, DOI 10.1111/iwj.12644
   Stephenson AJ, 2000, BRIT J PLAST SURG, V53, P397, DOI 10.1054/bjps.2000.3335
   Struk S, 2018, ANN CHIR PLAST ESTH, V63, P229, DOI 10.1016/j.anplas.2017.08.003
   Sun BK, 2014, SCIENCE, V346, P941, DOI 10.1126/science.1253836
   Suzuki S, 2000, BRIT J PLAST SURG, V53, P659, DOI 10.1054/bjps.2000.3426
   SUZUKI S, 1990, BRIT J PLAST SURG, V43, P47, DOI 10.1016/0007-1226(90)90044-Z
   Tallon B, 2009, DERMATOL SURG, V35, P634, DOI 10.1111/j.1524-4725.2009.01102.x
   Tam J, 2013, PRS-GLOB OPEN, V1, DOI 10.1097/GOX.0b013e3182a85a36
   Taylor BC, 2021, J AM ACAD ORTHOP SUR, V29, P855, DOI 10.5435/JAAOS-D-20-01389
   Tempfer H, 2018, CELL PHYSIOL BIOCHEM, V46, P1148, DOI 10.1159/000489057
   Tempfer H, 2015, FRONT PHYSIOL, V6, DOI 10.3389/fphys.2015.00330
   THIBAULT MJ, 1995, J AM ACAD DERMATOL, V32, P1004, DOI 10.1016/0190-9622(95)91340-8
   Wasiak J, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD002106.pub4
   Webster J, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub3
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Wolfe J R, 1875, Br Med J, V2, P360
   Xue X, 2021, INT WOUND J, V18, P639, DOI 10.1111/iwj.13565
   Yamaguchi Y, 2005, BRIT J DERMATOL, V152, P664, DOI 10.1111/j.1365-2133.2005.06401.x
   Yan HD, 2013, J TRAUMA ACUTE CARE, V74, P604, DOI 10.1097/TA.0b013e31827d5e00
   YANNAS IV, 1980, J BIOMED MATER RES, V14, P65, DOI 10.1002/jbm.820140108
   YANNAS IV, 1982, SCIENCE, V215, P174, DOI 10.1126/science.7031899
   Yeong EK, 2006, BURNS, V32, P375, DOI 10.1016/j.burns.2005.08.015
   Younes Nidal, 2006, Dermatol Online J, V12, P5
   Yuan XG, 2016, ORTHOP TRAUMATOL-SUR, V102, P369, DOI 10.1016/j.otsr.2016.01.020
   Zhang F, 2011, ANN PLAS SURG, V66, P581, DOI 10.1097/SAP.0b013e3182057376
   Zhang L, 2020, EXP THER MED, V20, P2305, DOI 10.3892/etm.2020.8941
NR 146
TC 1
Z9 5
U1 0
U2 7
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-875X
J9 FRONT SURG
JI Front. Surg.
PD SEP 15
PY 2022
VL 9
AR 953038
DI 10.3389/fsurg.2022.953038
PG 13
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 4Z6PZ
UT WOS:000862329300001
PM 36189402
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Gong, WB
   Li, JS
AF Gong, Wenbin
   Li, Junsheng
TI Combat with esophagojejunal anastomotic leakage after total gastrectomy
   for gastric cancer: A critical review of the literature
SO INTERNATIONAL JOURNAL OF SURGERY
LA English
DT Review
DE Gastric cancer; Total gastrectomy; Esophagojejunal anastomotic leakage;
   Risk factor; Treatment
ID THE-SCOPE CLIP; VACUUM-ASSISTED CLOSURE; LONG-TERM SURVIVAL; ENDOSCOPIC
   CLOSURE; CONTRAST SWALLOW; POSTOPERATIVE COMPLICATIONS; ROBOTIC
   GASTRECTOMY; COMPUTED-TOMOGRAPHY; ENTERAL NUTRITION; LINEAR STAPLER
AB Esophagojejunal anastomotic leakage (EJAL) is considered to be one of the most serious complications after total gastrectomy (TG), despite improvements in surgical instruments and technique. The occurrence of EJAL would cause poorer quality of life, prolonged hospital stay, and increased surgery-related costs and mortality. Although there is ever-increasing knowledge about EJAL, the optimal management is controversial. In the present review, we aim to demonstrate the effective management by focus on the possible risk factors, potentially useful preventive strategies, and several kinds of treatments in esophagojejunal anastomotic leakage after total gastrectomy for gastric cancer. (C) 2017 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
C1 [Gong, Wenbin] Southeast Univ, Sch Med, Nanjing, Jiangsu, Peoples R China.
   [Li, Junsheng] Affiliated Zhongda Hosp, Dept Gen Surg, Nanjing, Jiangsu, Peoples R China.
C3 Southeast University - China; Southeast University - China
RP Gong, WB (通讯作者)，87 DingjiaQaio, Nanjing 210009, Jiangsu, Peoples R China.
EM gongwenbin177810@163.com
RI Li, Junsheng/E-4990-2013
OI Gong, Wenbin/0000-0002-1699-9213
CR Akashi Y, 2012, LANGENBECK ARCH SURG, V397, P737, DOI 10.1007/s00423-012-0935-7
   [Anonymous], 2013, **DROPPED REF**, DOI DOI 10.1523/JNEUR0SCI.3042-12.2013
   Aurello P, 2015, AM SURGEON, V81, P450
   Babor Richard, 2009, Surg Laparosc Endosc Percutan Tech, V19, pe1, DOI 10.1097/SLE.0b013e318196c706
   Barlow R, 2011, CLIN NUTR, V30, P560, DOI 10.1016/j.clnu.2011.02.006
   Bludau M, 2014, SURG ENDOSC, V28, P896, DOI 10.1007/s00464-013-3244-5
   Bracale U, 2010, SURG ENDOSC, V24, P2475, DOI 10.1007/s00464-010-0988-z
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Brenkman HJF, 2016, J GASTROINTEST SURG, V20, P1908, DOI 10.1007/s11605-016-3235-7
   Brenkman HJF, 2016, WORLD J GASTROENTERO, V22, P4041, DOI 10.3748/wjg.v22.i15.4041
   Carboni F, 2016, J GASTROINTEST ONCOL, V7, P515, DOI 10.21037/jgo.2016.06.02
   Celik S, 2017, SCAND J SURG, V106, P62, DOI 10.1177/1457496916630652
   Conio M, 2010, ENDOSCOPY, V42, pE71, DOI 10.1055/s-0029-1215199
   Cools-Lartigue J, 2014, ANN SURG ONCOL, V21, P2573, DOI 10.1245/s10434-014-3654-1
   Daams F, 2013, WORLD J GASTROENTERO, V19, P2293, DOI 10.3748/wjg.v19.i15.2293
   Deguchi Y, 2012, WORLD J SURG, V36, P1617, DOI 10.1007/s00268-012-1559-3
   Deurenberg P, 2002, Obes Rev, V3, P141, DOI 10.1046/j.1467-789X.2002.00065.x
   Ebihara Y, 2013, LANGENBECK ARCH SURG, V398, P475, DOI 10.1007/s00423-013-1051-z
   El-Sourani N, 2017, POL J RADIOL, V82, P170, DOI 10.12659/PJR.899951
   Feith M, 2011, CLIN GASTROENTEROL H, V9, P202, DOI 10.1016/j.cgh.2010.12.010
   Freeman RK, 2007, J THORAC CARDIOV SUR, V133, P333, DOI 10.1016/j.jtcvs.2006.10.008
   Galizia G, 2012, J GASTROINTEST SURG, V16, P1585, DOI 10.1007/s11605-012-1862-1
   Girard E, 2014, J VISC SURG, V151, P441, DOI 10.1016/j.jviscsurg.2014.10.004
   Haga Y, 2011, WORLD J SURG, V35, P716, DOI 10.1007/s00268-010-0922-5
   Haverkamp L., 2015, ANN SURG ONCOL, V22, P1252
   Hogan BA, 2008, SURG ENDOSC, V22, P767, DOI 10.1007/s00464-007-9629-6
   Huang CM, 2017, ANN SURG ONCOL, V24, P1019, DOI 10.1245/s10434-016-5658-5
   Huang KH, 2012, J GASTROINTEST SURG, V16, P1303, DOI 10.1007/s11605-012-1874-x
   Hyun MH, 2013, ANN SURG ONCOL, V20, P1258, DOI 10.1245/s10434-012-2679-6
   Iacopini F, 2010, WORLD J GASTROENTERO, V16, P1665, DOI 10.3748/wjg.v16.i13.1665
   Inaba K, 2010, J AM COLL SURGEONS, V211, pE25, DOI 10.1016/j.jamcollsurg.2010.09.005
   Inokuchi M, 2015, WORLD J GASTROENTERO, V21, P9656, DOI 10.3748/wjg.v21.i32.9656
   Ito H, 2014, SURG ENDOSC, V28, P1929, DOI 10.1007/s00464-014-3417-x
   Jeong O, 2009, SURG ENDOSC, V23, P2624, DOI 10.1007/s00464-009-0461-z
   Kadowaki T, 2006, INT J OBESITY, V30, P1163, DOI 10.1038/sj.ijo.0803248
   Kanaji S, 2016, SURG TODAY, V46, P815, DOI 10.1007/s00595-015-1243-y
   Kang BH, 2012, J GASTRIC CANCER, V12, P156, DOI 10.5230/jgc.2012.12.3.156
   Kang KC, 2011, SURG ENDOSC, V25, P1953, DOI 10.1007/s00464-010-1493-0
   Kim HS, 2013, J LAPAROENDOSC ADV S, V23, P323, DOI 10.1089/lap.2012.0389
   Kim JJ, 2008, SURG ENDOSC, V22, P436, DOI 10.1007/s00464-007-9446-y
   Kim MC, 2010, SURG ENDOSC, V24, P610, DOI 10.1007/s00464-009-0618-9
   Kim SH, 2015, J GASTRIC CANCER, V15, P167, DOI 10.5230/jgc.2015.15.3.167
   Kinoshita T, 2010, SURG ENDOSC, V24, P2908, DOI 10.1007/s00464-010-1041-y
   Kirschniak A, 2011, SURG ENDOSC, V25, P2901, DOI 10.1007/s00464-011-1640-2
   Kosuga T, 2015, ANN SURG ONCOL, V22, P3606, DOI 10.1245/s10434-015-4417-3
   Krejs GJ, 2010, DIGEST DIS, V28, P600, DOI 10.1159/000320277
   LaFemina J, 2013, ANN SURG ONCOL, V20, P2975, DOI 10.1245/s10434-013-2978-6
   Lee IS, 2012, J LAPAROENDOSC ADV S, V22, P876, DOI 10.1089/lap.2012.0177
   Lee KM, 2010, GASTROINTEST ENDOSC, V72, P180, DOI 10.1016/j.gie.2010.02.052
   Lee S, 2013, SURG ENDOSC, V27, P4232, DOI 10.1007/s00464-013-3028-y
   Li QG, 2013, WORLD J GASTROENTERO, V19, P4060, DOI 10.3748/wjg.v19.i25.4060
   Manta R, 2011, ENDOSCOPY, V43, P545, DOI 10.1055/s-0030-1256196
   Marano L, 2013, ANN SURG ONCOL, V20, P3912, DOI 10.1245/s10434-013-3088-1
   Mariette C, 2012, ANN SURG ONCOL, V19, P2128, DOI 10.1245/s10434-012-2225-6
   Matsuda T, 2015, SURG ENDOSC, V29, P3386, DOI 10.1007/s00464-015-4073-5
   Messager M, 2017, EJSO-EUR J SURG ONC, V43, P258, DOI 10.1016/j.ejso.2016.06.394
   Migita K, 2012, J GASTROINTEST SURG, V16, P1659, DOI 10.1007/s11605-012-1932-4
   Moisan F, 2012, SURG ENDOSC, V26, P661, DOI 10.1007/s00464-011-1933-5
   Nagai E, 2013, SURGERY, V153, P732, DOI 10.1016/j.surg.2012.10.012
   Nishikawa K, 2010, SURG ENDOSC, V24, P2633, DOI 10.1007/s00464-010-1007-0
   Nunobe S, 2011, J GASTROINTEST SURG, V15, P1520, DOI 10.1007/s11605-011-1489-7
   Oh SJ, 2009, J GASTROINTEST SURG, V13, P239, DOI 10.1007/s11605-008-0716-3
   Okabe H, 2014, ANN SURG, V259, P109, DOI 10.1097/SLA.0b013e31828dfa5d
   Ott C, 2007, SURG ENDOSC, V21, P889, DOI 10.1007/s00464-006-9067-x
   Parisi A, 2017, WORLD J GASTROENTERO, V23, P2376, DOI 10.3748/wjg.v23.i13.2376
   Pohl J, 2010, ENDOSCOPY, V42, P757, DOI 10.1055/s-0030-1255634
   Raimondo D, 2014, CASE REP GASTROINTES, V2014, DOI 10.1155/2014/409283
   Schietroma M, 2013, ANN SURG ONCOL, V20, P1584, DOI 10.1245/s10434-012-2714-7
   Shim CN, 2014, SURG ENDOSC, V28, P833, DOI 10.1007/s00464-013-3228-5
   Sierzega M, 2010, BRIT J SURG, V97, P1035, DOI 10.1002/bjs.7038
   Smallwood NR, 2016, SURG ENDOSC, V30, P2473, DOI 10.1007/s00464-015-4501-6
   Strauss C, 2010, ANN SURG, V251, P647, DOI 10.1097/SLA.0b013e3181c1aeb8
   Sugisawa N, 2012, GASTRIC CANCER, V15, P206, DOI 10.1007/s10120-011-0099-0
   Takeuchi M, 2016, BMC SURG, V16, DOI 10.1186/s12893-016-0168-8
   Tanaka K, 2009, ANN SURG ONCOL, V16, P1520, DOI 10.1245/s10434-009-0391-y
   Tekinbas C, 2009, J THORAC CARDIOV SUR, V137, P766, DOI 10.1016/j.jtcvs.2008.01.052
   Tokunaga M, 2009, BRIT J SURG, V96, P496, DOI 10.1002/bjs.6586
   Topal B, 2008, SURG ENDOSC, V22, P980, DOI 10.1007/s00464-007-9549-5
   Traina M, 2010, ENDOSCOPY, V42, pE54, DOI 10.1055/s-0029-1243824
   Tsujimoto H, 2012, LANGENBECK ARCH SURG, V397, P833, DOI 10.1007/s00423-012-0939-3
   Tu RH, 2017, EJSO-EUR J SURG ONC, V43, P485, DOI 10.1016/j.ejso.2016.11.022
   Umemura A, 2015, ASIAN J SURG, V38, P102, DOI 10.1016/j.asjsur.2014.09.006
   van Boeckel PGA, 2011, ALIMENT PHARM THER, V33, P1292, DOI 10.1111/j.1365-2036.2011.04663.x
   Wang Q, 2008, WORLD J GASTROENTERO, V14, P5073, DOI 10.3748/wjg.14.5073
   Wedemeyer J, 2010, GASTROINTEST ENDOSC, V71, P382, DOI 10.1016/j.gie.2009.07.011
   Weiland T, 2013, SURG ENDOSC, V27, P2258, DOI 10.1007/s00464-012-2754-x
   Woo Y, 2011, ARCH SURG-CHICAGO, V146, P1086, DOI 10.1001/archsurg.2011.114
   Yamamoto M, 2014, HEPATO-GASTROENTEROL, V61, P543, DOI 10.5754/hge13918
   Yi HW, 2013, J GASTRIC CANCER, V13, P242, DOI 10.5230/jgc.2013.13.4.242
   Yoo HM, 2011, J SURG ONCOL, V104, P734, DOI 10.1002/jso.22045
NR 90
TC 36
Z9 47
U1 0
U2 9
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 1743-9191
EI 1743-9159
J9 INT J SURG
JI Int. J. Surg.
PD NOV
PY 2017
VL 47
BP 18
EP 24
DI 10.1016/j.ijsu.2017.09.019
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA FL2VJ
UT WOS:000414077500004
PM 28935529
DA 2026-07-24
ER

PT J
AU Costache, V
   Gaudreau, G
   Houde, C
   Rodière, M
   Hacini, R
   Blin, D
   Chavanon, O
AF Costache, V.
   Gaudreau, G.
   Houde, C.
   Rodiere, M.
   Hacini, R.
   Blin, D.
   Chavanon, O.
TI The assosciation of VAC® therapy, titanium plates osteosynthesis and
   bilateral pectoral muscle flaps in the management of postoperative
   mediastinitis in an obese and diabetic patient
SO ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE
LA French
DT Article
DE Postoperative mediastinitis; Titanium plates osteosynthesis; Negative
   pressure therapy; Bilateral pectoral muscle flaps
ID VACUUM-ASSISTED CLOSURE; STERNAL WOUND-INFECTION; POSTSTERNOTOMY
   MEDIASTINITIS; MEDIAN STERNOTOMY; HEART-SURGERY; RECONSTRUCTION;
   DEHISCENCE; FIXATION
AB Postoperative mediastinitis is one of the most worrisome complications after heart surgery. Until now there is no universally accepted strategy in the management of this infectious complication. Recently, various novel techniques like negative pressure therapy and titanium plates sternal reconstruction have allowed a dramatic decrease of mortality and morbidity after mediastinitis. We report the case of a diabetic patient suffering from morbid obesity who developed a severe postoperative mediastinitis after a coronary artery bypass; she was successfully treated by combining negative pressure therapy, titanium plates osteosynthesis and bilateral pectoral muscle flaps. (C) 2009 Elsevier Masson SAS. All rights reserved.
C1 [Costache, V.; Rodiere, M.; Hacini, R.; Blin, D.; Chavanon, O.] Univ Med Gr T Popa, CHU Grenoble, Serv Chirurg Cardiaque, F-38043 Grenoble 09, France.
   [Gaudreau, G.; Houde, C.] Hop Laval, Serv Chirurg Plast, Quebec City, PQ, Canada.
C3 Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA);
   CHU Grenoble Alpes; Laval University; Laval University Hospital
RP Costache, V (通讯作者)，Univ Med Gr T Popa, CHU Grenoble, Serv Chirurg Cardiaque, BP 217, F-38043 Grenoble 09, France.
EM vcostache@chu-grenoble.fr
RI CHAVANON, Olivier/AAC-8171-2019; Costache, Victor/AFC-8705-2022
OI CHAVANON, Olivier/0000-0001-8625-691X; 
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Baskett RJF, 1999, ANN THORAC SURG, V67, P462, DOI 10.1016/S0003-4975(98)01195-3
   Cicilioni OJ, 2005, PLAST RECONSTR SURG, V115, P1297, DOI 10.1097/01.PRS.0000156918.15595.85
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   Echahidi N, 2007, J AM COLL CARDIOL, V50, P843, DOI 10.1016/j.jacc.2007.04.075
   Eklund AM, 2006, ANN THORAC SURG, V82, P1784, DOI 10.1016/j.athoracsur.2006.05.097
   ElOakley RM, 1996, ANN THORAC SURG, V61, P1030, DOI 10.1016/0003-4975(95)01035-1
   Guedon C, 2003, Ann Chir Plast Esthet, V48, P115, DOI 10.1016/S0294-1260(03)00014-1
   Guedon C, 1994, Ann Chir Plast Esthet, V39, P191
   Gustafsson R, 2002, J THORAC CARDIOV SUR, V123, P895, DOI 10.1067/mtc.2002.121306
   Hollenbeak CS, 2000, CHEST, V118, P397, DOI 10.1378/chest.118.2.397
   JULIAN OC, 1957, SURGERY, V42, P753
   JURKIEWICZ MJ, 1980, ANN SURG, V191, P738, DOI 10.1097/00000658-198006000-00012
   Almodovar LFL, 2008, ANN THORAC SURG, V86, P1016, DOI 10.1016/j.athoracsur.2008.02.046
   Losanoff JE, 2002, CARDIOVASC SURG, V10, P102, DOI 10.1016/S0967-2109(01)00128-4
   Mohammadi S, 2007, CIRCULATION, V116, pE142, DOI 10.1161/CIRCULATIONAHA.107.706028
   Molina JE, 2006, J THORAC CARDIOV SUR, V132, P782, DOI 10.1016/j.jtcvs.2006.06.008
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   OTTINO G, 1987, ANN THORAC SURG, V44, P173, DOI 10.1016/S0003-4975(10)62035-8
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Thompson JT, 2007, CLIN PLAST SURG, V34, P673, DOI 10.1016/j.cps.2007.07.005
   Tocco MP, 2009, EUR J CARDIO-THORAC, V35, P833, DOI 10.1016/j.ejcts.2008.12.036
   Voss B, 2008, EUR J CARDIO-THORAC, V34, P139, DOI 10.1016/j.ejcts.2008.03.030
NR 23
TC 2
Z9 2
U1 0
U2 8
PU ELSEVIER
PI BRIDGEWATER
PA 685 ROUTE 202-206, BRIDGEWATER, NJ 08807 USA
SN 0294-1260
J9 ANN CHIR PLAST ESTH
JI Ann. Chir. Plast. Esthet.
PD DEC
PY 2010
VL 55
IS 6
BP 597
EP 602
DI 10.1016/j.anplas.2009.08.002
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 691MM
UT WOS:000285084600014
PM 19942336
DA 2026-07-24
ER

PT J
AU Schlosser, KA
   Otero, J
   Lincourt, A
   Augenstein, VA
AF Schlosser, Kathryn A.
   Otero, Javier
   Lincourt, Amy
   Augenstein, Vedra A.
TI Management of Surgical Incisions Using Incisional Negative-Pressure
   Therapy
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; COMPONENT SEPARATION TECHNIQUE; MICROVASCULAR
   BLOOD-FLOW; WOUND-THERAPY; SITE INFECTIONS; CLOSED INCISIONS; FINANCIAL
   IMPACT; HERNIA REPAIR; PREVENTION; CARE
AB Use of negative-pressure therapy (NPT) is a well-established therapy for chronic, open, contaminated wounds, promoting formation of granulation tissue and healing. The application of NPT after primary closure (ie, incisional NPT) has also been shown to reduce surgical site infection and surgical site occurrence in high-risk procedures across multiple disciplines. Incisional NPT is believed to decrease edema and shear stress, promote angiogenesis and lymphatic drainage, and increase vascular flow and scar formation. Incisional NPT may be considered when there is a high risk of surgical site occurrence or surgical site infection, particularly in procedures with nonautologous implants, such as hernia mesh or other permanent prosthetics. Here we discuss the proposed physiologic mechanism as demonstrated in animal models and review clinical outcomes across multiple specialties.
C1 [Schlosser, Kathryn A.; Otero, Javier; Lincourt, Amy; Augenstein, Vedra A.] Carolinas Med Ctr, Div Gastrointestinal & Minimally Invas Surg, Dept Surg, Charlotte, NC 28203 USA.
C3 Carolinas Medical Center
RP Augenstein, VA (通讯作者)，Carolinas Med Ctr, 1025 Morehead Med Dr,Suite 300, Charlotte, NC 28204 USA.
EM Vedra.Augenstein@atriumhealth.org
CR Adogwa O, 2014, SPINE J, V14, P2911, DOI 10.1016/j.spinee.2014.04.011
   Albright E, 2011, AM SURGEON, V77, P839
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1997, ANN PLAST SURG, V38, P577
   Atkins BZ, 2011, INT WOUND J, V8, P56, DOI 10.1111/j.1742-481X.2010.00743.x
   Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Blackham AU, 2013, AM J SURG, V205, P647, DOI 10.1016/j.amjsurg.2012.06.007
   Bonds AM, 2013, DIS COLON RECTUM, V56, P1403, DOI 10.1097/DCR.0b013e3182a39959
   Borgquist O, 2010, PLAST RECONSTR SURG, V125, P502, DOI 10.1097/PRS.0b013e3181c82e1f
   Burkhart RA, 2017, HPB, V19, P825, DOI 10.1016/j.hpb.2017.05.004
   Chadi SA, 2014, DIS COLON RECTUM, V57, P999, DOI 10.1097/DCR.0000000000000161
   Chopra K, 2016, PLAST RECONSTR SURG, V137, P1284, DOI 10.1097/PRS.0000000000002024
   Condé-Green A, 2013, ANN PLAS SURG, V71, P394, DOI 10.1097/SAP.0b013e31824c9073
   Cooper HJ, 2016, J ARTHROPLASTY, V31, P1047, DOI 10.1016/j.arth.2015.11.010
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   de Vries FEE, 2017, HERNIA, V21, P583, DOI 10.1007/s10029-017-1620-0
   De Vries FEE, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000004673
   Erba P, 2011, ANN SURG, V253, P402, DOI 10.1097/SLA.0b013e31820563a8
   Galiano RD, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001560
   Gassman A, 2015, HERNIA, V19, P273, DOI 10.1007/s10029-014-1312-y
   Glaser DA, 2012, WOUNDS, V24, P308
   Grauhan O, 2014, INT WOUND J, V11, P6, DOI 10.1111/iwj.12294
   Grauhan O, 2013, J THORAC CARDIOV SUR, V145, P1387, DOI 10.1016/j.jtcvs.2012.09.040
   Hansen E, 2013, CLIN ORTHOP RELAT R, V471, P3230, DOI 10.1007/s11999-013-2937-3
   Heniford BT, 2013, 2013 ANN M SO SURG A
   Jennings S, 2016, HEART LUNG CIRC, V25, P89, DOI 10.1016/j.hlc.2015.06.821
   Kilpadi DV, 2014, AESTHET PLAST SURG, V38, P767, DOI 10.1007/s00266-014-0339-x
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Kim DY, 2016, PLAST RECONSTR SURG, V138, P558, DOI 10.1097/PRS.0000000000002431
   LAWRENCE JC, 1994, AM J SURG, V167, pS21, DOI 10.1016/0002-9610(94)90006-X
   Lewis LS, 2014, GYNECOL ONCOL, V132, P684, DOI 10.1016/j.ygyno.2014.01.014
   Lo Torto F, 2017, INT WOUND J, V14, P1335, DOI 10.1111/iwj.12808
   Loveluck John, 2016, Eplasty, V16, pe20
   Lynam S, 2016, INT J GYNECOL CANCER, V26, P1525, DOI 10.1097/IGC.0000000000000792
   Maddox J, 2014, PAPER PRESENTED AT 2
   Magill SS, 2014, NEW ENGL J MED, V370, P1198, DOI 10.1056/NEJMoa1306801
   Malmsjö M, 2009, ANN PLAS SURG, V63, P676, DOI 10.1097/SAP.0b013e31819ae01b
   Masden D, 2012, ANN SURG, V255, P1043, DOI 10.1097/SLA.0b013e3182501bae
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   Mazzocchi M, 2011, AM J SURG, V201, P776, DOI 10.1016/j.amjsurg.2010.04.013
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mu Y, 2011, INFECT CONT HOSP EP, V32, P970, DOI 10.1086/662016
   Nordmeyer M, 2016, INT WOUND J, V13, P1176, DOI 10.1111/iwj.12436
   O'Leary DP, 2017, ANN SURG, V265, P1082, DOI 10.1097/SLA.0000000000002098
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Pauli EM, 2013, SURG INFECT, V14, P270, DOI 10.1089/sur.2012.059
   Pauser J, 2016, INT WOUND J, V13, P663, DOI 10.1111/iwj.12344
   Pellino G, 2014, INT J SURG, V12, pS64, DOI 10.1016/j.ijsu.2014.08.378
   Rodriguez-Unda N, 2015, J GASTROINTEST SURG, V19, P2054, DOI 10.1007/s11605-015-2894-0
   Rosenberger LH, 2011, SURG INFECT, V12, P163, DOI 10.1089/sur.2010.083
   Semsarzadeh NN, 2015, PLAST RECONSTR SURG, V136, P592, DOI 10.1097/PRS.0000000000001519
   Shepard J, 2013, JAMA SURG, V148, P907, DOI 10.1001/jamasurg.2013.2246
   Singh D, 2017, WOUNDS, V29, P175
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Suh H, 2016, ANN PLAS SURG, V76, P717, DOI 10.1097/SAP.0000000000000231
   Suissa D, 2011, PLAST RECONSTR SURG, V128, p498E, DOI 10.1097/PRS.0b013e31822b675c
   Swanson EW, 2016, PLAST SURG-CHIR PLAS, V24, P113, DOI 10.1177/229255031602400207
   Tauber R, 2013, J PLAST RECONSTR AES, V66, P390, DOI 10.1016/j.bjps.2012.09.030
   Tuffaha HW, 2015, J SURG RES, V195, P612, DOI 10.1016/j.jss.2015.02.008
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
   Zimlichman E, 2013, JAMA INTERN MED, V173, P2039, DOI 10.1001/jamainternmed.2013.9763
NR 66
TC 17
Z9 18
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0032-1052
EI 1529-4242
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD JAN
PY 2019
VL 143
IS 1
SU S
BP 15S
EP 20S
DI 10.1097/PRS.0000000000005307
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA IQ4PL
UT WOS:000480732600005
PM 30586098
DA 2026-07-24
ER

PT J
AU Dabizzi, E
   De Ceglie, A
   Baig, KRKK
   Baron, TH
   Conio, M
   Wallace, MB
AF Dabizzi, Emanuele
   De Ceglie, Antonella
   Baig, Kondal R. Kyanam Kabir
   Baron, Todd H.
   Conio, Massimo
   Wallace, Michael B.
TI Endoscopic "rescue'' treatment for gastrointestinal perforations,
   anastomotic dehiscence and fistula
SO CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; THE-SCOPE CLIP; EXPANDABLE METAL STENTS;
   COMBINED VICRYL PLUG; DUODENAL PERFORATION; SUBMUCOSAL DISSECTION; COLON
   PERFORATION; RISK-FACTORS; ESOPHAGEAL-PERFORATION; COLONOSCOPIC
   PERFORATIONS
AB Luminal perforations and anastomotic leaks of the gastrointestinal tract are life-threatening events with high morbidity and mortality. Early recognition and prompt therapy is essential for a favourable outcome. Surgery has long been considered the "gold standard'' approach for these conditions; however it is associated with high re-intervention morbidity and mortality. The recent development of endoscopic techniques and devices to manage perforations, leaks and fistulae has made non-surgical treatment an attractive and reasonable alternative approach. Although endoscopic therapy is widely accepted, comparative data of the different techniques are still lacking. In this review we describe, benefits and limitations of the current options in the management of patients with perforations and leaks, in order to improve outcomes. (C) 2015 Elsevier Masson SAS. All rights reserved.
C1 [Dabizzi, Emanuele] Univ Vita Salute San Raffaele, Gastroenterol & Digest Endoscopy Div, San Raffaele Sci Inst, Milan, Italy.
   [De Ceglie, Antonella; Conio, Massimo] G Borea Hosp, Gastroenterol & Digest Endoscopy Unit, San Remo, Italy.
   [Baig, Kondal R. Kyanam Kabir] Univ Alabama Birmingham, Div Gastroenterol & Hepatol, Birmingham, AL USA.
   [Baron, Todd H.] Univ N Carolina, Sch Med, Div Gastroenterol & Hepatol, Chapel Hill, NC USA.
   [Wallace, Michael B.] Mayo Clin, Div Gastroenterol & Hepatol, Jacksonville, FL 32224 USA.
C3 Vita-Salute San Raffaele University; IRCCS Ospedale San Raffaele;
   University of Alabama System; University of Alabama Birmingham;
   University of North Carolina; University of North Carolina Chapel Hill;
   University of North Carolina School of Medicine; Mayo Clinic
RP Dabizzi, E (通讯作者)，Univ Vita Salute San Raffaele, Gastroenterol & Digest Endoscopy Div, San Raffaele Sci Inst, Milan, Italy.
EM emadabi@yahoo.it
RI Wallace, Michael/GZL-9731-2022; Kyanam Kabir Baig, Kondal/AAD-7366-2020
OI Wallace, Michael/0000-0002-6446-5785; Kyanam Kabir Baig,
   Kondal/0000-0003-1550-4853
CR Abbas G, 2009, SURGERY, V146, P749, DOI 10.1016/j.surg.2009.06.058
   Amrani L, 2009, GASTROINTEST ENDOSC, V69, P1282, DOI 10.1016/j.gie.2008.09.043
   Anderson MA, 2012, GASTROINTEST ENDOSC, V75, P467, DOI 10.1016/j.gie.2011.07.010
   Anderson ML, 2000, AM J GASTROENTEROL, V95, P3418, DOI 10.1111/j.1572-0241.2000.03356.x
   Arezzo A, 2010, TECH COLOPROCTOL, V14, P279, DOI 10.1007/s10151-010-0569-0
   Banerjee S, 2012, GASTROINTEST ENDOSC, V76, P244, DOI 10.1016/j.gie.2012.02.028
   Baron TH, 2012, GASTROINTEST ENDOSC, V76, P838, DOI 10.1016/j.gie.2012.04.476
   Baron TH, 2012, GASTROINTEST ENDOSC, V76, P202, DOI 10.1016/j.gie.2012.03.250
   Basford PJ, 2012, THER ADV GASTROENTER, V5, P127, DOI 10.1177/1756283X11429590
   Ben-David K, 2011, ENDOSCOPY, V43, P160, DOI 10.1055/s-0030-1256094
   Ben-Menachem T, 2012, GASTROINTEST ENDOSC, V76, P707, DOI 10.1016/j.gie.2012.03.252
   Böhm G, 2010, ENDOSCOPY, V42, P599, DOI 10.1055/s-0029-1244165
   Bournet B, 2006, ENDOSCOPY, V38, P349, DOI 10.1055/s-2005-921173
   Branagan G, 2005, DIS COLON RECTUM, V48, P1021, DOI 10.1007/s10350-004-0869-4
   Bristow RE, 2003, J AM COLL SURGEONS, V197, P565, DOI 10.1016/S1072-7515(03)00478-2
   Cerná M, 2011, CARDIOVASC INTER RAD, V34, P1267, DOI 10.1007/s00270-010-0059-9
   Chiapponi C, 2011, BMC GASTROENTEROL, V11, DOI 10.1186/1471-230X-11-48
   Chirica M, 2010, J VISC SURG, V147, pE117, DOI 10.1016/j.jviscsurg.2010.08.003
   Cho SB, 2012, SURG ENDOSC, V26, P473, DOI 10.1007/s00464-011-1903-y
   Chopra SS, 2009, SURGERY, V145, P182, DOI 10.1016/j.surg.2008.09.012
   Chou KC, 2010, GASTROINTEST ENDOSC, V72, P218, DOI 10.1016/j.gie.2009.11.001
   Cooper CJ, 2014, DIAGN THER ENDOSC, V2014
   CWIKIEL W, 1993, RADIOLOGY, V187, P667, DOI 10.1148/radiology.187.3.8497612
   Dai YY, 2011, J THORAC CARDIOV SUR, V141, P1213, DOI 10.1016/j.jtcvs.2010.07.096
   deVries JH, 1997, GASTROINTEST ENDOSC, V45, P231, DOI 10.1016/S0016-5107(97)70264-5
   DiMaio CJ, 2012, GASTROINTEST ENDOSC, V76, P431, DOI 10.1016/j.gie.2012.03.1393
   El Hajj II, 2014, GASTROINTEST ENDOSC, V79, P589, DOI 10.1016/j.gie.2013.08.039
   Endo M., 2004, DIGEST ENDOSC, V16, P372, DOI DOI 10.1111/J.1443-1661.2004.00410.X
   Enestvedt BK, 2013, GASTROINTEST ENDOSC, V77, P464, DOI 10.1016/j.gie.2012.11.039
   Fan CS, 2007, GASTROINTEST ENDOSC, V66, P203, DOI 10.1016/j.gie.2006.11.025
   Fatima H, 2007, GASTROINTEST ENDOSC, V17, p145 
   Fatima J, 2007, ARCH SURG-CHICAGO, V142, P454, DOI [DOI 10.1001/ARCHSURG.142.5.448, 10.1001/ archsurg. 142.5.448]
   Fatima J, 2007, ARCH SURG-CHICAGO, V142, P448, DOI 10.1001/archsurg.142.5.448
   Freeman RK, 2012, ANN THORAC SURG, V94, P959, DOI 10.1016/j.athoracsur.2012.05.047
   Fusaroli P, 2005, DIGEST LIVER DIS, V37, P142, DOI 10.1016/j.dld.2004.11.003
   Giovannini M, 2003, ENDOSCOPY, V35, P511
   Gonzalez R, 2007, J AM COLL SURGEONS, V204, P47, DOI 10.1016/j.jamcollsurg.2006.09.023
   Grundy A, 1997, BRIT J RADIOL, V70, P846, DOI 10.1259/bjr.70.836.9486053
   Gubler C, 2012, DIGESTION, V85, P302, DOI 10.1159/000336509
   Haider Shahzad, 2010, Gastroenterol Hepatol (N Y), V6, P660
   Han JH, 2013, WORLD J GASTROENTERO, V19, P955, DOI 10.3748/wjg.v19.i6.955
   Hasan S, 2005, EUR J CARDIO-THORAC, V28, P7, DOI 10.1016/j.ejcts.2005.03.006
   Heldwein W, 2005, ENDOSCOPY, V37, P1116, DOI 10.1055/s-2005-870512
   Ho HC, 1996, AM SURGEON, V62, P770
   Ignjatovic M, 2009, LANGENBECK ARCH SURG, V394, P185, DOI 10.1007/s00423-008-0309-3
   Inoue T, 2014, DIGEST ENDOSC, V26, P220, DOI 10.1111/den.12104
   Iqbal CW, 2008, ARCH SURG-CHICAGO, V143, P701, DOI 10.1001/archsurg.143.7.701
   Jacobson BC, 2005, GASTROINTEST ENDOSC, V61, P8, DOI 10.1016/S0016-5107(04)02393-4
   Jenssen C, 2008, Z GASTROENTEROL, V46, P1177, DOI 10.1055/s-2008-1027334
   Jovanovic I, 2011, GASTROINTEST ENDOSC, V73, P550, DOI 10.1016/j.gie.2010.12.026
   Jung JH, 2013, ENDOSCOPY, V45, P133, DOI 10.1055/s-0032-1326178
   Kaneko T, 1999, GASTROINTEST ENDOSC, V50, P410, DOI 10.1053/ge.1999.v50.97235
   Khokhar Omar S, 2010, Gastroenterol Hepatol (N Y), V6, P657
   Kim DH, 2008, CURR PROBL DIAGN RAD, V37, P165, DOI 10.1067/j.cpradiol.2007.10.004
   Kim J, 2012, SURG ENDOSC, V26, P3293, DOI 10.1007/s00464-012-2343-z
   Kim JS, 2013, SURG ENDOSC, V27, P501, DOI 10.1007/s00464-012-2465-3
   Kruschewski M, 2007, INT J COLORECTAL DIS, V22, P919, DOI 10.1007/s00384-006-0260-0
   Kuehn F, 2012, J GASTROINTEST SURG, V16, P2145
   Lamazza A, 2015, ENDOSCOPY, V47, P270, DOI 10.1055/s-0034-1391403
   Lee HJ, 2015, SURG LAPARO ENDO PER, V25, pE76, DOI 10.1097/SLE.0000000000000143
   Lee TH, 2010, WORLD J GASTROENTERO, V16, P2305, DOI 10.3748/wjg.v16.i18.2305
   Leroy J, 2004, SURG ENDOSC, V18, P281, DOI 10.1007/s00464-002-8877-8
   Li GH, 2012, GASTROENT RES PRACT, V2012, DOI 10.1155/2012/657418
   Li ZS, 2006, GASTROINTEST ENDOSC, V64, P485, DOI 10.1016/j.gie.2006.01.059
   Lüning TH, 2007, SURG ENDOSC, V21, P994, DOI 10.1007/s00464-007-9251-7
   Machado NO, 2012, J PANCREAS, V13, P18
   Maeda Y, 2012, ENDOSCOPY, V44, P565, DOI 10.1055/s-0031-1291664
   Manta R, 2013, DIGEST LIVER DIS, V45, P879, DOI 10.1016/j.dld.2013.03.008
   Martínek J, 2013, SURG ENDOSC, V27, P1203, DOI 10.1007/s00464-012-2576-x
   Matsumoto S, 2013, ENDOSCOPY, V45, P136, DOI 10.1055/s-0032-1310123
   Matthes K, 2011, GASTROINTEST ENDOSC, V74, P1369, DOI 10.1016/j.gie.2011.07.057
   Mees ST, 2008, DIS COLON RECTUM, V51, P404, DOI 10.1007/s10350-007-9141-z
   Mennigen R, 2013, J GASTROINTEST SURG, V17, P1058, DOI 10.1007/s11605-013-2156-y
   Merchea A, 2010, SURGERY, V148, P876, DOI 10.1016/j.surg.2010.07.010
   Mercky P, 2015, DIGEST ENDOSC, V27, P18, DOI 10.1111/den.12295
   Mocciaro F, 2011, WORLD J GASTROENTERO, V17, P1088, DOI 10.3748/wjg.v17.i8.1088
   Mori H, 2013, DIGEST ENDOSC, V25, P459, DOI 10.1111/j.1443-1661.2012.01363.x
   Mutignani M, 2006, GASTROINTEST ENDOSC, V63, P725, DOI 10.1016/j.gie.2005.11.028
   Nakagawa Y, 2010, GASTROINTEST ENDOSC, V72, P216, DOI 10.1016/j.gie.2009.10.040
   Nesbakken A, 2005, COLORECTAL DIS, V7, P576, DOI 10.1111/j.1463-1318.2005.00870.x
   Nishiyama N, 2013, WORLD J GASTROENTERO, V19, P2752, DOI 10.3748/wjg.v19.i18.2752
   Panteris V, 2009, ENDOSCOPY, V41, P941, DOI 10.1055/s-0029-1215179
   PANZINI L, 1994, AM J GASTROENTEROL, V89, P367
   Parlak E, 2012, EUR J GASTROEN HEPAT, V24, P464, DOI 10.1097/MEG.0b013e32834f6017
   Parodi A, 2010, GASTROINTEST ENDOSC, V72, P881, DOI 10.1016/j.gie.2010.04.006
   Paspatis GA, 2014, ENDOSCOPY, V46, P693, DOI 10.1055/s-0034-1377531
   Roldán FP, 2013, GASTROINTEST ENDOSC, V77, P967, DOI 10.1016/j.gie.2013.01.043
   Pham BV, 2006, GASTROINTEST ENDOSC, V64, P113, DOI 10.1016/j.gie.2005.11.046
   Picasso M, 2013, CLIN RES HEPATOL GAS, V37, pE99, DOI 10.1016/j.clinre.2012.10.005
   Pross M, 2000, GASTROINTEST ENDOSC, V51, P73, DOI 10.1016/S0016-5107(00)70391-9
   Rabeneck L, 2011, GASTROINTEST ENDOSC, V73, P520, DOI 10.1016/j.gie.2010.10.034
   Rabeneck L, 2008, GASTROENTEROLOGY, V135, P1899, DOI 10.1053/j.gastro.2008.08.058
   Rabenstein T, 1999, GASTROINTEST ENDOSC, V50, P628, DOI 10.1016/S0016-5107(99)80010-8
   Rabie ME, 2013, ANN ROY COLL SURG, V95, P285, DOI 10.1308/003588413X13511609958578
   Raju Gottumukkala S, 2012, Gastroenterol Hepatol (N Y), V8, P548
   Raju GS, 2011, GASTROINTEST ENDOSC, V74, P1380, DOI 10.1016/j.gie.2011.08.007
   Raju GS, 2009, AM J GASTROENTEROL, V104, P1315, DOI 10.1038/ajg.2009.34
   Raju GS, 2005, GASTROINTEST ENDOSC, V62, P278, DOI 10.1016/S0016-5107(05)01632-9
   Rex DK, 2002, AM J GASTROENTEROL, V97, P1296, DOI 10.1016/S0002-9270(02)04168-0
   Riss S, 2010, COLORECTAL DIS, V12, pE104, DOI 10.1111/j.1463-1318.2009.01885.x
   Robison LS, 2007, WORLD J GASTROENTERO, V13, P2183, DOI 10.3748/wjg.v13.i15.2183
   Romero RV., 2013, Gastrointestinal Intervention, V2, P1, DOI DOI 10.1016/J.GII.2013.02.002
   Rullier E, 1998, BRIT J SURG, V85, P355
   Samarasena J B, 2012, Endoscopy, V44 Suppl 2 UCTN, pE424, DOI 10.1055/s-0032-1325738
   Schorsch T, 2013, SURG ENDOSC, V27, P2040, DOI 10.1007/s00464-012-2707-4
   Scileppi T, 2005, GASTROINTEST ENDOSC, V62, P643, DOI 10.1016/j.gie.2005.04.005
   Sebastian S, 2004, ENDOSCOPY, V36, P245, DOI 10.1055/s-2004-814257
   Seibert DG, 2003, ENDOSCOPY, V35, P189, DOI 10.1055/s-2003-37004
   Shim CN, 2014, SURG ENDOSC, V28, P833, DOI 10.1007/s00464-013-3228-5
   Sieg A, 2001, GASTROINTEST ENDOSC, V53, P620, DOI 10.1067/mge.2001.114422
   Singhal S, 2013, J CLIN GASTROENTEROL, V47, P749, DOI 10.1097/MCG.0b013e318296ecb9
   Song HY, 2008, GASTROINTEST ENDOSC, V68, P713, DOI 10.1016/j.gie.2007.12.051
   Soreide Jon Arne, 2011, Scand J Trauma Resusc Emerg Med, V19, P66, DOI 10.1186/1757-7241-19-66
   Srinivasamurthy D, 2013, TECH COLOPROCTOL, V17, P275, DOI 10.1007/s10151-012-0911-9
   Swan MP, 2011, GASTROINTEST ENDOSC, V73, P79, DOI 10.1016/j.gie.2010.07.003
   Swinnen J, 2011, GASTROINTEST ENDOSC, V73, P890, DOI 10.1016/j.gie.2010.12.019
   Takimoto K, 2012, Endoscopy, V44 Suppl 2 UCTN, pE414, DOI 10.1055/s-0032-1325739
   Truong S, 2004, SURG ENDOSC, V18, P1105, DOI 10.1007/s00464-003-8286-7
   Tsereteli Z, 2008, SURGERY, V144, P786, DOI 10.1016/j.surg.2008.05.018
   Vakalopoulos KA, 2013, J SURG RES, V180, P290, DOI 10.1016/j.jss.2012.12.043
   van Boeckel PGA, 2011, ALIMENT PHARM THER, V33, P1292, DOI 10.1111/j.1365-2036.2011.04663.x
   van Boeckel PGA, 2011, CLIN GASTROENTEROL H, V9, P653, DOI 10.1016/j.cgh.2011.04.006
   van der Sluis FJ, 2012, COLORECTAL DIS, V14, pE187, DOI 10.1111/j.1463-1318.2011.02841.x
   van Heel NCM, 2010, AM J GASTROENTEROL, V105, P1515, DOI 10.1038/ajg.2010.104
   van Koperen PJ, 2009, SURG ENDOSC, V23, P1379, DOI 10.1007/s00464-008-0186-4
   Voermans RP, 2011, ENDOSCOPY, V43, P217, DOI 10.1055/s-0030-1256072
   Voermans RP, 2012, CLIN GASTROENTEROL H, V10, P603, DOI 10.1016/j.cgh.2012.02.005
   von Bernstorff W, 2009, INT J COLORECTAL DIS, V24, P819, DOI 10.1007/s00384-009-0673-7
   von Renteln D, 2010, GASTROINTEST ENDOSC, V71, P1267, DOI 10.1016/j.gie.2009.12.056
   von Renteln D, 2009, GASTROINTEST ENDOSC, V70, P732, DOI 10.1016/j.gie.2009.03.010
   Voudoukis E, 2012, ENDOSCOPY, V44, pE292, DOI 10.1055/s-0032-1310027
   Wedemeyer J, 2010, GASTROINTEST ENDOSC, V71, P382, DOI 10.1016/j.gie.2009.07.011
   Weidenhagen R, 2008, Rozhl Chir, V87, P397
   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
   Won DY, 2012, AM SURGEON, V78, P550
   Wu Hao M, 2006, HPB (Oxford), V8, P393, DOI 10.1080/13651820600700617
   Wu JT, 2007, J TRAUMA, V63, P1173, DOI 10.1097/TA.0b013e31805c0dd4
   Wullstein C, 1999, SURG ENDOSC-ULTRAS, V13, P484, DOI 10.1007/s004649901018
NR 138
TC 5
Z9 8
U1 0
U2 4
PU ELSEVIER MASSON, CORP OFF
PI PARIS
PA 65 CAMILLE DESMOULINS CS50083 ISSY-LES-MOULINEAUX, 92442 PARIS, FRANCE
SN 2210-7401
EI 2210-741X
J9 CLIN RES HEPATOL GAS
JI Clin. Res. Hepatol. Gastroenterol.
PD FEB
PY 2016
VL 40
IS 1
BP 28
EP 40
DI 10.1016/j.clinre.2015.04.006
PG 13
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA DC0OM
UT WOS:000368917200010
PM 26209869
DA 2026-07-24
ER

PT J
AU Lowe, JB III
AF Lowe, JB III
TI Updated algorithm for abdominal wall reconstruction
SO CLINICS IN PLASTIC SURGERY
LA English
DT Article
ID TENSOR FASCIAE LATAE; EXPANDED POLYTETRAFLUOROETHYLENE PATCH; COMPONENTS
   SEPARATION METHOD; INFERIOR EPIGASTRIC FLAP; VACUUM-ASSISTED CLOSURE;
   POLYPROPYLENE MESH; MYOCUTANEOUS FLAP; CLINICAL-EXPERIENCE; VENTRAL
   HERNIA; GROIN HERNIAS
AB Like any clinical regime, the algorithm for abdominal wall reconstruction requires routine updating as new options and techniques become available. Increased experience and understanding of new applications have allowed for improvements to the approach to complex abdominal wall defects. These improvements have increased efficiency and decreased risk, particularly in the area of staged reconstruction. Surgeons have continued to rely heavily on autologous reconstruction and local tissue advancement for long-term dynamic support. The current approach to abdominal wall reconstruction is based on understanding the literature, clinical experience, and the type of patients seen in practice. This article provides surgeons with the basic guidelines to follow when faced with complex abdominal wall defects and the tools necessary to solve these difficult problems in a responsible and reliable way.
C1 Washington Univ, Sch Med, St Louis, MO 63110 USA.
C3 Washington University (WUSTL)
RP Lowe, JB III (通讯作者)，Washington Univ, Sch Med, 660 S Euclid Ave,Box 8324, St Louis, MO 63110 USA.
EM lowej@wustl.edu
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   ARGENTA LC, 1985, CLIN PLAST SURG, V12, P159
   BARIE PS, 1995, AM J SURG, V170, P62, DOI 10.1016/S0002-9610(99)80254-2
   BLEICHRODT RP, 1993, SURG GYNECOL OBSTET, V176, P18
   BOSTWICK J, 1979, PLAST RECONSTR SURG, V63, P186, DOI 10.1097/00006534-197902000-00006
   BROWN DM, 1993, SURGERY, V114, P112
   Butler CE, 2004, PLAST RECONSTR SURG, V114, P464, DOI 10.1097/01.PRS.0000132670.81794.7E
   BYRD HS, 1989, PLAST RECONSTR SURG, V84, P347, DOI 10.1097/00006534-198908000-00026
   CAFFEE HH, 1983, PLAST RECONSTR SURG, V71, P348, DOI 10.1097/00006534-198303000-00010
   CAULFIELD WH, 1994, ANN PLAS SURG, V32, P377, DOI 10.1097/00000637-199404000-00010
   Classen D, 1999, ANN PLAS SURG, V42, P137, DOI 10.1097/00000637-199902000-00005
   CORE GB, 1995, AESTHETIC RECONSTRUC, P1327
   DeFranzo AJ, 1996, ANN PLAS SURG, V37, P18, DOI 10.1097/00000637-199607000-00003
   DIBBELL DG, 1991, PLAST RECONSTR SURG, V87, P60, DOI 10.1097/00006534-199101000-00011
   DiBello JN, 1996, PLAST RECONSTR SURG, V98, P464, DOI 10.1097/00006534-199609000-00016
   DIEBEL LN, 1992, J TRAUMA, V33, P279, DOI 10.1097/00005373-199208000-00019
   Disa JJ, 1998, PLAST RECONSTR SURG, V101, P979, DOI 10.1097/00006534-199804040-00014
   Dowden R V, 1980, Ann Plast Surg, V4, P396, DOI 10.1097/00000637-198005000-00007
   Duffy A J, 2004, Hernia, V8, P358, DOI 10.1007/s10029-004-0258-x
   EARLE AS, 1975, PLAST RECONSTR SURG, V56, P447, DOI 10.1097/00006534-197510000-00018
   FABIAN TC, 1994, ANN SURG, V219, P643, DOI 10.1097/00000658-199406000-00007
   Felemovicius I, 2004, J AM COLL SURGEONS, V198, P543, DOI 10.1016/j.jamcollsurg.2003.12.004
   FRY DE, 1991, SURG CLIN N AM, V71, P1
   GER R, 1983, PLAST RECONSTR SURG, V72, P170, DOI 10.1097/00006534-198308000-00008
   Girotto JA, 1999, ANN PLAS SURG, V42, P385, DOI 10.1097/00000637-199904000-00007
   GOTTLIEB JR, 1990, PLAST RECONSTR SURG, V86, P281, DOI 10.1097/00006534-199008000-00013
   GOTTLIEB ME, 1986, PLAST RECONSTR SURG, V78, P782, DOI 10.1097/00006534-198678060-00012
   GRAVES G, 1980, CLIN BULL, V10, P144
   Gruen RL, 1998, AUST NZ J SURG, V68, P666, DOI 10.1111/j.1445-2197.1998.tb04841.x
   HILL HL, 1978, PLAST RECONSTR SURG, V61, P517, DOI 10.1097/00006534-197804000-00004
   HOBAR PC, 1994, PLAST RECONSTR SURG, V94, P379, DOI 10.1097/00006534-199408000-00027
   HOUSTON GC, 1988, PLAST RECONSTR SURG, V81, P917, DOI 10.1097/00006534-198806000-00015
   Hurwotz DJ, 1994, MASTERY PLASTIC RECO, P1349
   Jacobsen WM, 1997, PLAST RECONSTR SURG, V100, P326, DOI 10.1097/00006534-199708000-00007
   Johnson EK, 2004, AM SURGEON, V70, P657
   Kolker AR, 2005, ANN PLAS SURG, V55, P36, DOI 10.1097/01.sap.0000168248.83197.d4
   KOSHIMA I, 1989, BRIT J PLAST SURG, V42, P645, DOI 10.1016/0007-1226(89)90075-1
   LARSON GM, 1984, SURG CLIN N AM, V64, P335
   LAW NW, 1991, SURGERY, V109, P652
   Lowe JB, 2000, PLAST RECONSTR SURG, V105, P720, DOI 10.1097/00006534-200002000-00039
   Lowe JB III, 2003, PLAST RECONSTR SURG, V111, P1276, DOI 10.1097/01.PRS.0000047021.36879.FD
   MATHES SJ, 1977, BRIT J PLAST SURG, V30, P282, DOI 10.1016/0007-1226(77)90118-7
   Mathes SJ, 2000, ANN SURG, V232, P586, DOI 10.1097/00000658-200010000-00014
   Mathes SJ., 1997, Reconstructive surgery: principles, anatomy technique, V1st
   Mathes SJ., 1982, Clinical application for muscle and musculocutaneous flaps
   Matthews BD, 2005, J SURG RES, V123, P227, DOI 10.1016/j.jss.2004.08.012
   Menon NG, 2003, ANN PLAS SURG, V50, P523, DOI 10.1097/01.SAP.0000044252.76804.6B
   MILLARD DR, 1969, PLAST RECONSTR SURG, V43, P569, DOI 10.1097/00006534-196906000-00002
   MILLER SH, 1990, CLIN PLAST SURG, V17, P503
   MORRIS JA, 1993, ANN SURG, V217, P576, DOI 10.1097/00000658-199305010-00019
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   NAHAI F, 1979, PLAST RECONSTR SURG, V63, P788, DOI 10.1097/00006534-197963060-00004
   Ninkovic M, 1997, CHIRURG, V68, P1163, DOI 10.1007/s001040050339
   OHTSUKA H, 1984, BRIT J PLAST SURG, V37, P327, DOI 10.1016/0007-1226(84)90075-4
   PARKASH S, 1983, BRIT J SURG, V70, P68, DOI 10.1002/bjs.1800700204
   POWANDA MC, 1981, SURG GYNECOL OBSTET, V153, P749
   RAMASASTRY SS, 1985, ANN PLAS SURG, V15, P57, DOI 10.1097/00000637-198507000-00007
   RAMIREZ OM, 1990, PLAST RECONSTR SURG, V86, P519, DOI 10.1097/00006534-199009000-00023
   RICHARDS WO, 1983, ANN SURG, V197, P183, DOI 10.1097/00000658-198302000-00010
   ROBINSON DW, 1975, PLAST RECONSTR SURG, V55, P41, DOI 10.1097/00006534-197501000-00007
   ROBSON MC, 1990, CLIN PLAST SURG, V17, P485
   Rohrich RJ, 2000, PLAST RECONSTR SURG, V105, P202, DOI 10.1097/00006534-200001000-00036
   SILBERMAN DA, 1985, ANN PLAS SURG, V15, P170, DOI 10.1097/00000637-198508000-00015
   SPEAR SL, 1992, PLAST RECONSTR SURG, V90, P608, DOI 10.1097/00006534-199210000-00009
   STERN HS, 1992, BRIT J PLAST SURG, V45, P270, DOI 10.1016/0007-1226(92)90050-8
   Stoppa R, 1996, ANN CHIR, V50, P808
   STOPPA R, 1975, INT SURG, V60, P411
   STOPPA RE, 1989, WORLD J SURG, V13, P545, DOI 10.1007/BF01658869
   STOPPA RE, 1986, INT SURG, V71, P154
   TEMPLE WJ, 1975, ANN SURG, V182, P93, DOI 10.1097/00000658-197508000-00001
   TERASHI H, 1995, ANN PLAS SURG, V35, P320, DOI 10.1097/00000637-199509000-00018
   THOMAS WO, 1993, PLAST RECONSTR SURG, V91, P1080, DOI 10.1097/00006534-199305000-00017
   VENUGOPALAN S, 1980, BRIT J PLAST SURG, V33, P43, DOI 10.1016/0007-1226(80)90051-X
   VOYLES CR, 1981, ANN SURG, V194, P219, DOI 10.1097/00000658-198108000-00017
   Williams JK, 1998, PLAST RECONSTR SURG, V101, P713, DOI 10.1097/00006534-199803000-00020
   Young Ricardo M, 2004, Curr Surg, V61, P77, DOI 10.1016/j.cursur.2003.09.011
NR 76
TC 26
Z9 33
U1 0
U2 2
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0094-1298
EI 1558-0504
J9 CLIN PLAST SURG
JI Clin. Plast. Surg.
PD APR
PY 2006
VL 33
IS 2
BP 225
EP +
DI 10.1016/j.cps.2005.12.004
PG 17
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 039AD
UT WOS:000237270500006
PM 16638465
DA 2026-07-24
ER

PT J
AU Dessy, LA
   Serratore, F
   Corrias, F
   Parisi, P
   Mazzocchi, M
   Carlesimo, B
AF Dessy, Luca A.
   Serratore, Francesco
   Corrias, Federico
   Parisi, Paola
   Mazzocchi, Marco
   Carlesimo, Bruno
TI Retention of polyurethane foam fragments during VAC therapy: a
   complication to be considered
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article
DE Foam-fragments retention; Healing; Negative pressure therapy
ID NEGATIVE-PRESSURE THERAPY; SPINAL WOUND INFECTIONS; THICKNESS
   SKIN-GRAFTS; ASSISTED CLOSURE; TRIAL
AB Vacuum-assisted closure (VAC) therapy is a closed-loop, non-invasive active system, characterised by a controlled and localised negative pressure applied on porous polyurethane absorbent foams. It promotes healing of acute and chronic wounds. Therapeutic effects of VAC therapy have been proved and demonstrated; however, this method can have some disadvantages. Even if it is a quite versatile device, only qualified medical/paramedical personnel should use it in order to avoid possible complications that can occur after an improper application. In this report, 11 cases of foam-fragment retention within the wound are presented. This rare complication did not promote healing, but further hindered it. On the basis of our experience, it is mandatory to define the indications, benefits and limitations of VAC therapy.
C1 [Dessy, Luca A.; Serratore, Francesco; Corrias, Federico; Parisi, Paola; Carlesimo, Bruno] Univ Roma La Sapienza, Dept Plast & Reconstruct Surg, I-00185 Rome, Italy.
   [Mazzocchi, Marco] Univ Perugia, Dept Plast & Reconstruct Surg, I-06100 Perugia, Italy.
C3 Sapienza University Rome; University of Perugia
RP Serratore, F (通讯作者)，Univ Roma La Sapienza, Dept Plast & Reconstruct Surg, Piazzale Aldo Moro 5, I-00185 Rome, Italy.
EM serratorefrancesco@yahoo.it
RI PARISI, PAOLA/ACJ-8116-2022
OI PARISI, PAOLA/0000-0003-2639-2957
FU NHLBI NIH HHS [R01 HL066053] Funding Source: Medline; Wellcome Trust
   Funding Source: Medline
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Black Joyce, 2007, Dermatol Nurs, V19, P343
   Center EE, 2009, BP NEG PRESS WOUND T
   Chester DL, 2002, BRIT J PLAST SURG, V55, P510, DOI 10.1054/bjps.2002.3890
   DISA JJ, 1992, PLAST RECONSTR SURG, V89, P272, DOI 10.1097/00006534-199202000-00012
   Dzwierzynski WW, 1998, PLAST RECONSTR SURG, V102, P2006, DOI 10.1097/00006534-199811000-00030
   Eaglstein WH, 1997, SURG CLIN N AM, V77, P689, DOI 10.1016/S0039-6109(05)70575-2
   Egemen O, 2012, INT WOUND J, V9, P199, DOI 10.1111/j.1742-481X.2011.00876.x
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Granick MS, 1998, PLAST RECONSTR SURG, V101, P1243, DOI 10.1097/00006534-199804050-00011
   Gwan-Nulla DN, 2001, ANN PLAS SURG, V47, P552, DOI 10.1097/00000637-200111000-00014
   Jones GA, 2007, J NEUROSURG-SPINE, V6, P407, DOI 10.3171/spi.2007.6.5.407
   Joseph E, 2000, WOUNDS, V12, P60
   Kaufman Melissa W, 2003, Dermatol Nurs, V15, P317
   KCI, 2004, VAC THER CLIN GUID
   Kloth Luther C, 2002, Adv Skin Wound Care, V15, P226, DOI 10.1097/00129334-200209000-00008
   Landau AG, 2008, ANN PLAS SURG, V60, P661, DOI 10.1097/SAP.0b013e318146c288
   McCallon S K, 2000, Ostomy Wound Manage, V46, P28
   Mendez-Eastman S, 2001, Adv Skin Wound Care, V14, P314, DOI 10.1097/00129334-200111000-00015
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mouës CM, 2011, AM J SURG, V201, P544, DOI 10.1016/j.amjsurg.2010.04.029
   Patel NV, 2009, AM SURGEON, V75, P349
   Petkar KS, 2011, BURNS, V37, P925, DOI 10.1016/j.burns.2011.05.013
   Ploumis A, 2008, J SPINAL DISORD TECH, V21, P320, DOI 10.1097/BSD.0b013e318141f99d
   Preston Georgina, 2008, Nurs Stand, V23, P62
   Sartipy U, 2006, ANN THORAC SURG, V82, P1110, DOI 10.1016/j.athoracsur.2006.01.060
   Sibbald R Gary, 2003, Ostomy Wound Manage, V49, P52
   STAL S, 1983, ANN PLAS SURG, V11, P347, DOI 10.1097/00000637-198310000-00016
   Stannard JP, 2010, INJURY, V41, P780, DOI 10.1016/j.injury.2009.08.011
   White RA, 2005, J ORTHOP TRAUMA, V19, P56, DOI 10.1097/00005131-200501000-00011
NR 30
TC 12
Z9 15
U1 0
U2 11
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD APR
PY 2015
VL 12
IS 2
BP 132
EP 136
DI 10.1111/iwj.12062
PG 5
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA CE2EI
UT WOS:000351626400003
PM 23590296
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Stannard, JP
   Atkins, BZ
   O'Malley, D
   Singh, H
   Bernstein, B
   Fahey, M
   Masden, D
   Attinger, CE
AF Stannard, James P.
   Atkins, Broadus Zane
   O'Malley, David
   Singh, Hardayal
   Bernstein, Brent
   Fahey, Michael
   Masden, Derek
   Attinger, Christopher E.
TI Use of Negative Pressure Therapy on Closed Surgical Incisions: A Case
   Series
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; PERISTERNAL THORACIC
   WALL; WOUND THERAPY; BLOOD-FLOW; MULTICENTER
AB Multiple patient comorbidities and environmental factors increase the risk of incisional wound complications. The literature suggests that negative pressure therapy (NPT) on clean closed surgical incisions may help reduce the risk of wound infections and other complications. In this case study, NPT was applied in the operating room to clean closed surgical wounds in four high-risk patients (two men, two women) following coronary artery bypass grafting using bilateral internal mammary arteries, transmetatarsal amputation, and abdominal hysterectomy. All wounds healed well. These results and currently available information suggest that prospective, randomized, controlled clinical studies to assess the safety, efficacy and cost-effectiveness of NPT in the prevention of postoperative wound complications are warranted. In addition, if studies confirm the validity and reliability of the proposed patient grading system discussed, it may help guide use of NPT in postsurgical patients.
C1 [Stannard, James P.] Univ Alabama Birmingham, Sch Med, Dept Orthopaed Trauma, Birmingham, AL USA.
   [Atkins, Broadus Zane] VA Med Ctr, Durham, NC USA.
   [O'Malley, David] Ohio State Univ, James Graham Brown Canc Ctr, Coll Med, Columbus, OH 43210 USA.
   [O'Malley, David] Ohio State Univ, Coll Med, Solove Res Inst, Columbus, OH 43210 USA.
   [Singh, Hardayal] SE Orthoped Sports Med & Shoulder Ctr, Raleigh, NC USA.
   [Bernstein, Brent] St Lukes Hosp, Charcot & Reconstruct Foot Program, Allentown, PA USA.
   [Bernstein, Brent] St Lukes Hosp, Charcot & Reconstruct Foot Program, Bethlehem, PA USA.
   [Fahey, Michael] Fremont Rideout Hlth Grp, Yuba City, CA USA.
   [Attinger, Christopher E.] Georgetown Univ Hosp, Dept Surg Otolaryngol & Orthopaed Surg, Washington, DC 20007 USA.
   [Attinger, Christopher E.] Georgetown Limb Ctr, Washington, DC USA.
C3 University of Alabama System; University of Alabama Birmingham;
   University System of Ohio; Ohio State University; University System of
   Ohio; Ohio State University; James Cancer Hospital & Solove Research
   Institute; Georgetown University
RP Stannard, JP (通讯作者)，Care Of Martinez R R, KCI Med Dept, San Antonio, TX USA.
EM ricardo.martinez@kci1.com
RI /AAQ-9524-2020
OI Stannard, James P/0000-0001-8467-6494
CR Abbas SM, 2009, ANZ J SURG, V79, P247, DOI 10.1111/j.1445-2197.2009.04854.x
   ARGENTA LC, 1994, 4 ANN M EUR TISS REP
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   ATKINS BZ, 2009, SURG INNOV      0521
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Easterlin B, 2007, WOUNDS, V19, P331
   Ennis WJ, 2005, OSTOMY WOUND MANAG, V51, P24
   Fowler VG, 2005, CIRCULATION, V112, pI358, DOI 10.1161/CIRCULATIONAHA.104.525790
   Gomoll AH, 2006, J ORTHOP TRAUMA, V20, P705, DOI 10.1097/01.bot.0000211159.98239.d2
   Hollenbeak CS, 2000, CHEST, V118, P397, DOI 10.1378/chest.118.2.397
   Holm C, 1998, EUR J SURG, V164, P179
   Ichioka S, 2008, WOUND REPAIR REGEN, V16, P460, DOI 10.1111/j.1524-475X.2008.00390.x
   KAYE KS, 2006, J THORAC CARDIOVASC, V132, P537
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Petzina R, 2006, EUR J CARDIO-THORAC, V30, P85, DOI 10.1016/j.ejcts.2006.04.009
   RIOU JPA, 1992, AM J SURG, V163, P324, DOI 10.1016/0002-9610(92)90014-I
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   STANNARD JP, 2007, ANN M ORTH TRAUM ASS
   Veves A, 2001, DIABETES CARE, V24, P290, DOI 10.2337/diacare.24.2.290
   Wackenfors A, 2004, WOUND REPAIR REGEN, V12, P600, DOI 10.1111/j.1067-1927.2004.12602.x
   Wackenfors A, 2005, ANN THORAC SURG, V79, P1724, DOI 10.1016/j.athoracsur.2004.10.053
   Wilson Joyce A, 2004, Adv Skin Wound Care, V17, P426, DOI 10.1097/00129334-200410000-00013
   WU LC, 1995, SURGERY, V117, P570, DOI 10.1016/S0039-6060(05)80257-0
   Yousaf M, 2004, DIS COLON RECTUM, V47, P1403, DOI 10.1007/s10350-004-0576-1
NR 24
TC 1
Z9 2
U1 0
U2 3
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD AUG
PY 2009
VL 21
IS 8
BP 221
EP 228
PG 8
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 490BU
UT WOS:000269472900007
PM 25903674
DA 2026-07-24
ER

PT J
AU Huang, JH
   Li, J
   Li, RC
   Wu, X
   Lei, YX
   Zhou, ZG
AF Huang, Jihui
   Li, Jun
   Li, Ruichen
   Wu, Xing
   Lei, Yuanxue
   Zhou, Zhiguo
TI Infectious wrist arthritis complicating acute carpal tunnel syndrome in
   a child: A CARE-compliant case report
SO MEDICINE
LA English
DT Article
DE acute carpal tunnel syndrome; case report; children; infectious wrist
   arthritis; vacuum sealing drainage
ID SEPTIC ARTHRITIS
AB Introduction:The objective of this case report is to provide clinical evidence that acute infectious wrist arthritis in children can lead to the rare condition of acute carpal tunnel syndrome (ACTS). This article discusses in detail the characteristics of infectious wrist arthritis complicating ACTS in children in terms of etiology, pathogenic bacteria, treatment modalities, and sequelae to improve the understanding of this disease.Patient concerns:A 10-year-old male child presented with a 15-day history of swelling and pain in the left forearm, wrist, and hand.Diagnoses:Left-sided infected wrist arthritis complicating ACTS.Interventions:The child received emergency surgery and anti-infective treatment combined with regular rehabilitation.Outcomes:During the treatment period, the child's wrist pain and swelling gradually improved, and wrist movement was restored compared with the preoperative period. At 6-month follow-up, the activities of the metacarpophalangeal joints of the left hand were close to normal, and the flexion of the left wrist joint was slightly limited.Conclusion:In infectious wrist arthritis in children, ACTS is a serious complication that requires aggressive surgical carpal tunnel release to avoid median nerve injury in addition to anti-infective therapy.
C1 [Huang, Jihui; Li, Ruichen] Wuhan Univ Sci & Technol, Med Coll, Wuhan, Peoples R China.
   [Li, Jun; Wu, Xing; Lei, Yuanxue; Zhou, Zhiguo] Huazhong Univ Sci & Technol, Wuhan Childrens Hosp, Wuhan Maternal & Child Healthcare Hosp, Tongji Med Coll, Wuhan 430019, Peoples R China.
C3 Wuhan University of Science & Technology; Huazhong University of Science
   & Technology
RP Zhou, ZG (通讯作者)，Huazhong Univ Sci & Technol, Wuhan Childrens Hosp, Wuhan Maternal & Child Healthcare Hosp, Tongji Med Coll, Wuhan 430019, Peoples R China.
EM 18327696030@163.com; lrc6760@163.com; lrc6760@163.com; 948571927@qq.com;
   leiyuanxue@zgwhfe.com; mlpnk999@163.com
RI Li, RuiChen/JVZ-4755-2024
CR Ahlawat S, 2017, CLIN RADIOL, V72, DOI 10.1016/j.crad.2016.11.020
   Birman MV, 2011, J HAND SURG-AM, V36A, P324, DOI 10.1016/j.jhsa.2010.11.034
   Choudhury MM, 2023, J WRIST SURG, V12, P549, DOI 10.1055/s-0042-1749657
   Dadras M, 2018, J PLAST RECONSTR AES, V71, P1138, DOI 10.1016/j.bjps.2018.04.017
   GERARDI JA, 1989, J AM OSTEOPATH ASSOC, V89, P933
   Krauss S, 2022, J HAND SURG-EUR VOL, V47, P812, DOI 10.1177/17531934221101805
   Ku Ying C, 2023, J Hand Surg Glob Online, V5, P606, DOI [10.1016/j.jhsg.2023.06.012, 10.1016/j.jhsg.2023.06.012]
   Li Y, 2023, J PEDIATR ORTHOPED, V43, P46, DOI 10.1097/BPO.0000000000002266
   Low SL, 2020, J HAND MICROSURG, V12, P19, DOI 10.1055/s-0039-1693068
   Parnes N., 2022, JBJS Case Connect, V12, pe22.00066
   Silver JM, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.7444
   STRONG M, 1995, J PEDIATR ORTHOPED, V15, P152
   Yang RF, 2023, J ORTHOP SURG RES, V18, DOI 10.1186/s13018-023-04259-6
   Yoshida H, 2017, INTERNAL MED, V56, P1439, DOI 10.2169/internalmedicine.56.7584
   Zbeda Robert M, 2021, J Orthop Case Rep, V11, P100, DOI [10.13107/jocr.2021.v11.i04.2170, 10.13107/jocr.2021.v11.i04.2170]
NR 15
TC 1
Z9 1
U1 1
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD AUG 16
PY 2024
VL 103
IS 33
AR e39276
DI 10.1097/MD.0000000000039276
PG 4
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA C9Q1N
UT WOS:001292625200035
PM 39151517
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Lu, W
   Cao, Y
   Zeng, FH
   Chen, C
   Yang, ZY
   Qi, ZL
   Yang, XA
AF Lu, Wei
   Cao, Yan
   Zeng, Fanhua
   Chen, Chun
   Yang, Zhenyu
   Qi, Zuoliang
   Yang, Xiaonan
TI Surgical Treatment for Benign Lymphangioendothelioma After Two
   Incomplete Excisions: A Case and Literature Review
SO CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
LA English
DT Review
DE diagnosis lymphangiomatosis; Kaposi's sarcoma; angiosarcoma. acquired
   progressive lymphangioma; angiosarcoma; benign lymphangioendothelioma;
   lymphangioma; lymphangiomatosis
ID ACQUIRED PROGRESSIVE LYMPHANGIOMA; KAPOSIS-SARCOMA; CLINICOPATHOLOGICAL
   ANALYSIS; ANGIOENDOTHELIOMA; PATCH; SKIN
AB Benign lymphangioendothelioma (BL) is a rare, poorly identified, slow-growing benign vascular lesion characterized by asymptomatic, solitary, well-demarcated macules, or by mildly infiltrated plaque. We report a case of an atypical BL that arose as a tender, protuberant, flesh-colored mass with cyanotic vesicles, and then progressed to a persistent exudative wound after two incomplete excisions. The patient was also diagnosed with thoracic duct narrowing. Although the stenosis was removed by surgery, the right lower extremity ulceration and exudation did not improve. Thus, we performed a thorough excision and split-thickness skin graft transplant following vacuum sealing drainage, and eventually the patient had a favorable functional and cosmetic outcome. A biopsy revealed irregular, dilated vascular spaces lined with a single layer of flat endothelial cells extending from the superficial dermis to the subcutis that did not reach the striated muscles. Additionally, by reviewing the literature on BL, in this paper we summarize the diverse pathogenic, morphological, and immunohistochemical presentations for this rare disease, as well as the histopathological differential diagnosis of lymphangiomatosis, Kaposi's sarcoma, and angiosarcoma.
C1 [Lu, Wei; Zeng, Fanhua; Chen, Chun; Yang, Zhenyu; Qi, Zuoliang; Yang, Xiaonan] Chinese Acad Med Sci CAMS & Peking Union Med Coll, Plast Surg Hosp, Dept Hemangioma & Vasc Malformat, Beijing 100144, Peoples R China.
   [Cao, Yan] Chinese Acad Med Sci CAMS & Peking Union Med Coll, Plast Surg Hosp, Dept Pathol, Beijing, Peoples R China.
   [Zeng, Fanhua] Ningxiang Peoples Hosp, Dept Burn & Plast Surg, Ningxiang, Hunan, Peoples R China.
   [Chen, Chun] Shenzhen Longgang Dist Third Peoples Hosp, ENT Dept, Shenzhen, Guangdong, Peoples R China.
C3 Chinese Academy of Medical Sciences - Peking Union Medical College;
   Peking Union Medical College; Cancer Institute & Hospital - CAMS;
   Chinese Academy of Medical Sciences - Peking Union Medical College;
   Cancer Institute & Hospital - CAMS; Peking Union Medical College
RP Yang, XA (通讯作者)，Chinese Acad Med Sci CAMS & Peking Union Med Coll, Plast Surg Hosp, Dept Hemangioma & Vasc Malformat, Beijing 100144, Peoples R China.
EM yxnan@aliyun.com
OI Lu, Wei/0000-0001-5396-4004
FU National Major Disease Multidisciplinary Diagnosis and Treatment
   Cooperation Project [1112320139]; National clinical key specialty
   construction project [23003]
FX Funding This study was financially supported by the National Major
   Disease Multidisciplinary Diagnosis and Treatment Cooperation Project
   (No.1112320139) and the National clinical key specialty construction
   project (23003) . The funding body played no role in the design of the
   study and collection, analysis, and interpretation of data and in
   writing the manuscript.
CR Agha RA, 2020, INT J SURG, V84, P226, DOI 10.1016/j.ijsu.2020.10.034
   Alkhalili Eyas, 2014, BMJ Case Rep, V2014, DOI 10.1136/bcr-2014-205966
   Ando K, 2009, EUR J DERMATOL, V19, P82, DOI 10.1684/ejd.2008.0556
   Audard V, 2003, ANN PATHOL, V23, P345
   Cossu S, 1997, AM J DERMATOPATH, V19, P16, DOI 10.1097/00000372-199702000-00004
   Elder D., 2014, LEVERS HISTOPATHOLOG
   Faul JL, 2000, AM J RESP CRIT CARE, V161, P1037, DOI 10.1164/ajrccm.161.3.9904056
   FLEISCHMANN W, 1993, UNFALLCHIRURG, V96, P488
   Flores S, 2014, DERMATOL SURG, V40, P218, DOI 10.1111/dsu.12383
   Gengler C, 2007, CANCER, V109, P1584, DOI 10.1002/cncr.22586
   GOLD SC, 1970, BRIT J DERMATOL, V82, P92
   Grunwald MH, 1997, J AM ACAD DERMATOL, V37, P656, DOI 10.1016/S0190-9622(97)70192-0
   Guillou L, 2000, AM J SURG PATHOL, V24, P1047, DOI 10.1097/00000478-200008000-00002
   HERRON GS, 1994, J AM ACAD DERMATOL, V31, P362, DOI 10.1016/S0190-9622(94)70173-3
   Hunt KM, 2014, J AM ACAD DERMATOL, V71, pE221, DOI 10.1016/j.jaad.2014.07.054
   Hwang LY, 2003, J AM ACAD DERMATOL, V49, pS250, DOI 10.1067/S0190-9622(03)00448-1
   JONES EW, 1963, P ROY SOC MED, V56, P299, DOI 10.1177/003591576305600429
   JONES EW, 1976, CLIN EXP DERMATOL, V1, P287
   JONES EW, 1990, J AM ACAD DERMATOL, V23, P229, DOI 10.1016/0190-9622(90)70203-T
   JONES EW, 1964, BRIT J DERMATOL, V76, P21, DOI 10.1111/j.1365-2133.1964.tb13970.x
   Kato H, 1996, CLIN EXP DERMATOL, V21, P159, DOI 10.1111/j.1365-2230.1996.tb00044.x
   Kim HS, 2007, J EUR ACAD DERMATOL, V21, P416, DOI 10.1111/j.1468-3083.2006.01904.x
   Larkin SC, 2018, PEDIATR DERMATOL, V35, P486, DOI 10.1111/pde.13486
   Lin SS, 2009, CLIN EXP DERMATOL, V34, pe341, DOI 10.1111/j.1365-2230.2009.03286.x
   Lindberg M, 2019, Diagnostic pathology: kidney diseases
   McKay MJ, 2017, ANN TRANSL MED, V5, DOI 10.21037/atm.2017.03.19
   MEHREGAN DR, 1992, J CUTAN PATHOL, V19, P502, DOI 10.1111/j.1600-0560.1992.tb01604.x
   MEUNIER L, 1994, BRIT J DERMATOL, V131, P706, DOI 10.1111/j.1365-2133.1994.tb04988.x
   Mizuno K, 2015, INT J DERMATOL, V54, pE273, DOI 10.1111/ijd.12805
   Paik AS, 2007, J CUTAN PATHOL, V34, P882, DOI 10.1111/j.1600-0560.2007.00747.x
   RENSHAW AA, 1993, AM J SURG PATHOL, V17, P557, DOI 10.1097/00000478-199306000-00003
   Revelles JM, 2012, J CUTAN PATHOL, V39, P950, DOI 10.1111/j.1600-0560.2012.01971.x
   ROSSO R, 1995, J CUTAN PATHOL, V22, P164, DOI 10.1111/j.1600-0560.1995.tb01401.x
   Rudra O, 2017, INDIAN J DERMATOL, V62, P528, DOI 10.4103/ijd.IJD_416_16
   Salman A, 2017, PEDIATR DERMATOL, V34, pE302, DOI 10.1111/pde.13283
   Schnebelen AM, 2015, J CUTAN PATHOL, V42, P217, DOI 10.1111/cup.12453
   Sevila A, 2000, AM J DERMATOPATH, V22, P151, DOI 10.1097/00000372-200004000-00011
   SOOHOO L, 1995, ARCH DERMATOL, V131, P343, DOI 10.1001/archderm.1995.01690150107022
   TADAKI T, 1988, ARCH DERMATOL, V124, P699, DOI 10.1001/archderm.124.5.699
   Teixeira D, 2022, J CUTAN PATHOL, V49, P86, DOI 10.1111/cup.14125
   Tong PL, 2011, ANN ACAD MED SINGAP, V40, P106
   Tronnier M, 2021, HAUTARZT, V72, P610, DOI 10.1007/s00105-020-04728-7
   Vittal NK, 2016, J CLIN DIAGN RES, V10, pWD1, DOI 10.7860/JCDR/2016/15664.7155
   Wang L, 2013, J CUTAN PATHOL, V40, P945, DOI 10.1111/cup.12216
   WATANABE M, 1983, J AM ACAD DERMATOL, V8, P663, DOI 10.1016/S0190-9622(83)70076-9
   Weiss S W., 2007, Enzinger and Weisss soft tissue tumors
   Wilmer A, 1998, J AM ACAD DERMATOL, V39, P126, DOI 10.1016/S0190-9622(98)70416-5
   Yamada S, 2014, DIAGN PATHOL, V9, DOI 10.1186/s13000-014-0197-5
   Yiannias JA, 2001, CUTIS, V67, P29
   Zhu JW, 2014, CUTIS, V93, P316
   ZHU WY, 1991, J AM ACAD DERMATOL, V24, P813, DOI 10.1016/0190-9622(91)70120-Q
NR 51
TC 2
Z9 2
U1 0
U2 2
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
SN 1178-7015
J9 CLIN COSMET INV DERM
JI CLIN. COSMET. INVESTIG. DERMATOL.
PY 2023
VL 16
BP 2697
EP 2719
DI 10.2147/CCID.S420019
PG 23
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA T3YX7
UT WOS:001077388300001
PM 37790904
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kouretas, PC
   Burch, PT
   Kaza, AK
   Lambert, LM
   Witte, MK
   Everitt, MD
   Siddiqi, FA
AF Kouretas, Peter C.
   Burch, Phillip T.
   Kaza, Aditya K.
   Lambert, Linda M.
   Witte, Madolin K.
   Everitt, Melanie D.
   Siddiqi, Faizi A.
TI Management of Deep Wound Complications With Vacuum-Assisted Therapy
   After Berlin Heart EXCOR Ventricular Assist Device Placement in the
   Pediatric Population
SO ARTIFICIAL ORGANS
LA English
DT Article
DE Pediatrics; Vacuum-assisted closure; Ventricular assist device; Wound
   complications
ID CLOSURE; INFECTION; SUPPORT
AB Wound complications after ventricular assist device (VAD) placement remain a formidable challenge to surgeons. The Berlin Heart EXCOR VAD is a versatile pulsatile system that has been successful in pediatric patients of all ages and sizes. Prevention of device-related complications such as infection, particularly in pediatric patients, remains an essential issue in minimizing patient morbidity and mortality. The introduction of vacuum-assisted wound closure (VAC) therapy and its application in VAD-related wound complications provide an efficient and effective method for wound healing. We report our experience in the management of deep wound complications in two pediatric patients after placement of the Berlin Heart EXCOR VAD. The wound VAC system proved to achieve complete wound healing without any infectious complications.
C1 [Kouretas, Peter C.; Burch, Phillip T.; Kaza, Aditya K.; Lambert, Linda M.; Siddiqi, Faizi A.] Univ Utah, Primary Childrens Med Ctr, Dept Surg, Salt Lake City, UT USA.
   [Witte, Madolin K.; Everitt, Melanie D.] Univ Utah, Primary Childrens Med Ctr, Dept Pediat, Salt Lake City, UT USA.
C3 Utah System of Higher Education; University of Utah; Utah System of
   Higher Education; University of Utah
RP Kouretas, PC (通讯作者)，100 N Mario Capecchi Dr,Suite 2800, Salt Lake City, UT 84113 USA.
EM peter.kouretas@hsc.utah.edu
RI Kaza, Aditya/AAE-2116-2019
OI Kaza, Aditya/0000-0003-3450-4496
CR Arabía FA, 2006, J HEART LUNG TRANSPL, V25, P16, DOI 10.1016/j.healun.2005.07.003
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Garatti A, 2007, J HEART LUNG TRANSPL, V26, P956, DOI 10.1016/j.healun.2007.06.007
   Holman WL, 2004, J HEART LUNG TRANSPL, V23, P1359, DOI 10.1016/j.healun.2003.09.025
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Sjögren J, 2005, ANN THORAC SURG, V79, P2049, DOI 10.1016/j.athoracsur.2004.12.048
   Stiller B, 2005, EUR J CARDIO-THORAC, V28, P234, DOI 10.1016/j.ejcts.2005.04.023
   Yuh DD, 2005, ANN THORAC SURG, V80, P1493, DOI 10.1016/j.athoracsur.2004.03.043
NR 8
TC 16
Z9 18
U1 0
U2 1
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0160-564X
EI 1525-1594
J9 ARTIF ORGANS
JI Artif. Organs
PD NOV
PY 2009
VL 33
IS 11
BP 922
EP 925
DI 10.1111/j.1525-1594.2009.00950.x
PG 4
WC Engineering, Biomedical; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Transplantation
GA 524EY
UT WOS:000272127800008
PM 19874282
DA 2026-07-24
ER

PT J
AU Çetinkaya, C
   Batirel, HF
AF Cetinkaya, Cagatay
   Batirel, Hasan Fevzi
TI Current Treatment for Mediastinitis
SO THORACIC SURGERY CLINICS
LA English
DT Article
DE Mediastinitis; Sternal wound infections; Post-surgical mediastinitis;
   Infection; Surgical wound infection
ID INFECTIOUS-DISEASES SOCIETY; STERNAL WOUND-INFECTION; VACUUM-ASSISTED
   CLOSURE; MANAGEMENT; PREVENTION; COMPLICATIONS; GUIDELINES; CONSENSUS
AB Mediastinitis-whether following sternotomy, descending cervicogenic spread, or esophageal leak-demands rapid recognition, imaging-defined anatomy, and timely source control paired with evidence-based antimicrobials and early nutrition. Classification systems (DSWI stability/viability, endo's CT-based patterns, and leak severity/ viability after esophagectomy) are most useful as decision modifiers: they help choose access (cervical, thoracic, and combined; open vs minimally invasive), determine the need for sternal stabilization or vascularized coverage, and guide when endoscopic options are reasonable versus when operative diversion/reconstruction is required. NPWT works best as a short, structured bridge in contaminated/ uncertain fields; outcomes improve when teams move to definitive closure or diversion once sepsis abates and viable margins are confirmed. Across etiologies, planned short-interval reassessment, microbiology-guided deescalation, and multidisciplinary coordination underpin shorter stays and fewer recurrences.
C1 [Cetinkaya, Cagatay] Uskudar Univ, Dept Thorac Surg, Sch Med, Istanbul, Turkiye.
   [Batirel, Hasan Fevzi] Biruni Univ, Sch Med, Dept Thorac Surg, Gultepe Mah Halkali Cd 99, TR-34295 Istanbul, Turkiye.
C3 Uskudar University; Biruni University
RP Batirel, HF (通讯作者)，Biruni Univ, Sch Med, Dept Thorac Surg, Gultepe Mah Halkali Cd 99, TR-34295 Istanbul, Turkiye.
EM hbatirel@marmara.edu.tr
RI Çetinkaya, Çağatay/JAX-2330-2023
CR Abu-Omar Y, 2017, EUR J CARDIO-THORAC, V51, P10, DOI 10.1093/ejcts/ezw326
   Allen KB, 2017, J THORAC CARDIOV SUR, V153, P888, DOI 10.1016/j.jtcvs.2016.10.093
   Bouza E, 2021, J CLIN MED, V10, DOI 10.3390/jcm10235566
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Brinster CJ, 2004, ANN THORAC SURG, V77, P1475, DOI 10.1016/j.athoracsur.2003.08.037
   Cardillo G, 2022, FRONT SURG, V9, DOI 10.3389/fsurg.2022.1049126
   Carter BW, 2014, J THORAC ONCOL, V9, pS97, DOI 10.1097/JTO.0000000000000292
   Chirica M, 2019, WORLD J EMERG SURG, V14, DOI 10.1186/s13017-019-0245-2
   Douville EC, 2004, ANN THORAC SURG, V78, P1659, DOI 10.1016/j.athoracsur.2004.04.082
   Endo S, 1999, Jpn J Thorac Cardiovasc Surg, V47, P14
   Evans L, 2021, INTENS CARE MED, V47, P1181, DOI [10.1097/CCM.0000000000005357, 10.1007/s00134-021-06506-y]
   Fumagalli U, 2019, WORLD J GASTROENTERO, V25, P356, DOI 10.3748/wjg.v25.i3.356
   Hasegawa T, 2000, ANN THORAC SURG, V69, P1296, DOI 10.1016/S0003-4975(00)01117-6
   Hever P, 2021, JPRAS OPEN, V28, P77, DOI 10.1016/j.jpra.2021.02.007
   Jolles H, 1996, RADIOLOGY, V201, P463, DOI 10.1148/radiology.201.2.8888241
   Kalil AC, 2016, CLIN INFECT DIS, V63, pE61, DOI 10.1093/cid/ciw353
   Kaman L, 2010, GASTROENTEROL RES, V3, P235, DOI 10.4021/gr263w
   Kappus S, 2025, STATPEARLS
   Lazar H, 2018, INDIAN J THORAC CARD, V34, P349, DOI 10.1007/s12055-018-0686-3
   Libânio D, 2023, ENDOSCOPY, V55, P361, DOI 10.1055/a-2031-0874
   Liu YT, 2024, INT J SURG, V110, P8107, DOI 10.1097/JS9.0000000000002138
   Low DE, 2015, ANN SURG, V262, P286, DOI 10.1097/SLA.0000000000001098
   Pappas PG, 2016, CLIN INFECT DIS, V62, pE1, DOI 10.1093/cid/civ933
   Perezgrovas-Olaria R, 2023, ANN THORAC SURG, V115, P272, DOI 10.1016/j.athoracsur.2022.04.054
   Prado-Calleros HM, 2016, HEAD NECK-J SCI SPEC, V38, pE2275, DOI 10.1002/hed.24183
   ROBICSEK F, 1977, J THORAC CARDIOV SUR, V73, P267
   Sartipy U, 2006, ANN THORAC SURG, V82, P1110, DOI 10.1016/j.athoracsur.2006.01.060
   Singh Kimberly, 2011, Semin Plast Surg, V25, P25, DOI 10.1055/s-0031-1275168
   Son HS, 2006, SURG LAPARO ENDO PER, V16, P379, DOI 10.1097/01.sle.0000213726.72709.62
   Stoddard N, 2025, STATPEARLS
NR 30
TC 0
Z9 0
U1 0
U2 0
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1547-4127
EI 1558-5069
J9 THORAC SURG CLIN
JI Thorac. Surg. Clin.
PD AUG
PY 2026
VL 36
IS 3
BP 337
EP 349
DI 10.1016/j.thorsurg.2026.02.012
EA JUN 2026
PG 13
WC Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Respiratory System; Surgery
GA KI4IC
UT WOS:001807706200002
PM 42336512
DA 2026-07-24
ER

PT J
AU Elsayed, NA
   Amer Diabet Assoc Professional Practice Comm
   McCoy, RG
   Aleppo, G
   Beverly, EA
   Early, KB
   Bruemmer, D
   Echouffo-Tcheugui, JB
   Ekhlaspour, L
   Garg, R
   Khunti, K
   Lal, R
   Lingvay, I
   Matfin, G
   Pandya, N
   Pilla, SJ
   Polsky, S
   Segal, AR
   Seley, JJ
   Stanton, RC
   Bannuru, RR
AF Elsayed, Nuha A.
   American Diabetes Association Professional Practice Committee, Rozalina G.
   McCoy, Rozalina G.
   Aleppo, Grazia
   Beverly, Elizabeth A.
   Early, Kathaleen Briggs
   Bruemmer, Dennis
   Echouffo-Tcheugui, Justin B.
   Ekhlaspour, Laya
   Garg, Rajesh
   Khunti, Kamlesh
   Lal, Rayhan
   Lingvay, Ildiko
   Matfin, Glenn
   Pandya, Naushira
   Pilla, Scott J.
   Polsky, Sarit
   Segal, Alissa R.
   Seley, Jane Jeffrie
   Stanton, Robert C.
   Bannuru, Raveendhara R.
TI 12. Retinopathy, Neuropathy, and Foot Care: Standards of Care in
   Diabetes-2025
SO DIABETES CARE
LA English
DT Review
ID PROLIFERATIVE DIABETIC-RETINOPATHY; CONTROL-CARDIOVASCULAR-RISK;
   INTENSIVE INSULIN THERAPY; HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED
   CLOSURE; PERIPHERAL NEUROPATHY; COMPLICATIONS TRIAL/EPIDEMIOLOGY;
   DOUBLE-BLIND; PANRETINAL PHOTOCOAGULATION; ORTHOSTATIC HYPOTENSION
AB The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
RI ; Bannuru, Raveendhara/G-2601-2011; Briggs Early,
   Kathaleen/AAB-6388-2019; Echouffo-Tcheugui, Justin/AGD-6195-2022;
   Lingvay, Ildiko/AGL-9548-2022; Polsky, Sarit/AAT-3067-2020
OI Beverly, Elizabeth/0000-0002-6486-8234; Bannuru,
   Raveendhara/0000-0002-8069-5783; Briggs Early,
   Kathaleen/0000-0003-2224-2548; McCoy, Rozalina/0000-0002-2289-3183;
   ElSayed, Nuha/0000-0003-1217-4916; Segal, Alissa/0000-0003-4895-9598;
   Aleppo, Grazia/0000-0003-1644-5947; 
CR Abràmoff MD, 2018, NPJ DIGIT MED, V1, DOI 10.1038/s41746-018-0040-6
   Afshinnia F, 2022, ANN CLIN TRANSL NEUR, V9, P1392, DOI 10.1002/acn3.51639
   Agardh E, 2011, DIABETES CARE, V34, P1318, DOI 10.2337/dc10-2308
   Aghili R, 2019, OBES SURG, V29, P3010, DOI 10.1007/s11695-019-04004-1
   Aiello LP, 2015, NEW ENGL J MED, V372, P1722, DOI 10.1056/NEJMoa1409463
   Albers JW, 2010, DIABETES CARE, V33, P1090, DOI 10.2337/dc09-1941
   Albers JW, 1995, ANN NEUROL, V38, P869, DOI 10.1002/ana.410380607
   Andersen ST, 2018, DIABETES CARE, V41, P1068, DOI 10.2337/dc17-2062
   Ang L, 2014, CURR DIABETES REP, V14, P1, DOI 10.1007/s11892-014-0528-7
   [Anonymous], 1976, Am J Ophthalmol, V81, P383
   [Anonymous], 1993, NEW ENGL J MED, V329, P977, DOI [DOI 10.1056/NEJM199309303291401, 10.1056/NEJM1993093032914018366922, DOI 10.1056/NEJM1993093032914018366922]
   [Anonymous], 1985, Arch Ophthalmol, V103, P1796, DOI 10.1001/archopht.1985.01050120030015
   [Anonymous], 2024, National diabetes statistics report 2024
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Asha Mohammad Z, 2019, Sultan Qaboos Univ Med J, V19, pe291, DOI [10.18295/squmj.2019.19.04.004, 10.18295/SQUMJ.2019.19.04.004]
   Baker CW, 2019, JAMA-J AM MED ASSOC, V321, P1880, DOI 10.1001/jama.2019.5790
   Bethel MA, 2021, DIABETES CARE, V44, P290, DOI 10.2337/dc20-1815
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Boulton AJM, 2022, New Evidence-Based Therapies for Complex Diabetic Foot Wounds, American Diabetes Association © 2022 by American Diabetes Association. All rights reserved. None of the contents may be reproduced without the written permission of the American Diabetes Association, V2022, P1
   Boulton AJM, 2008, DIABETES CARE, V31, P1679, DOI 10.2337/dc08-9021
   Bragge P, 2011, ARCH OPHTHALMOL-CHIC, V129, P435, DOI 10.1001/archophthalmol.2010.319
   Briasoulis A, 2014, J CLIN HYPERTENS, V16, P141, DOI 10.1111/jch.12258
   Bril V, 2011, PM&R, V3, P345, DOI [10.1016/j.pmrj.2011.03.008, 10.1212/WNL.0b013e3182166ebe]
   Bus SA, 2016, DIABETES-METAB RES, V32, P99, DOI 10.1002/dmrr.2702
   Bus SA, 2024, DIABETES-METAB RES, V40, DOI 10.1002/dmrr.3647
   Bus SA, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3269
   Callaghan BC, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD007543.pub2
   Callaghan BC, 2021, OBESITY, V29, P2108, DOI 10.1002/oby.23246
   Callaghan BC, 2016, DIABETES CARE, V39, P801, DOI 10.2337/dc16-0081
   Camilleri M, 2022, AM J GASTROENTEROL, V117, P1197, DOI 10.14309/ajg.0000000000001874
   Carter MJ, 2023, ADV WOUND CARE, V12, P177, DOI 10.1089/wound.2022.0041
   Chew EY, 2014, OPHTHALMOLOGY, V121, P2443, DOI 10.1016/j.ophtha.2014.07.019
   Chew EY, 2010, NEW ENGL J MED, V363, P233, DOI 10.1056/NEJMoa1001288
   Conte MS, 2019, EUR J VASC ENDOVASC, V58, pS1, DOI 10.1016/j.ejvs.2019.05.006
   Dabelea D, 2017, JAMA-J AM MED ASSOC, V317, P825, DOI 10.1001/jama.2017.0686
   Daskivich LP, 2017, JAMA INTERN MED, V177, P642, DOI 10.1001/jamainternmed.2017.0204
   Diabet Control Complications Trial Res Grp, 1998, DIABETOLOGIA, V41, P416
   Diabetes Control and Complications, 2000, DIABETES CARE, V23, P1084
   Dowell D, 2016, JAMA-J AM MED ASSOC, V315, P1624, DOI 10.1001/jama.2016.1464
   Dworkin RH, 2007, J PAIN, V8, P118, DOI 10.1016/j.jpain.2006.06.005
   Elman MJ, 2011, OPHTHALMOLOGY, V118, P609, DOI 10.1016/j.ophtha.2010.12.033
   Estacio RO, 1998, AM J KIDNEY DIS, V31, P947, DOI 10.1053/ajkd.1998.v31.pm9631838
   Fedorko L, 2016, DIABETES CARE, V39, P392, DOI 10.2337/dc15-2001
   Figueroa JJ, 2010, CLEV CLIN J MED, V77, P298, DOI 10.3949/ccjm.77a.09118
   Franklin GM, 2014, NEUROLOGY, V83, P1277, DOI 10.1212/WNL.0000000000000839
   Freeman R, 2009, CURR DIABETES REP, V9, P423, DOI 10.1007/s11892-009-0069-7
   Frykberg RG, 2022, DIABETES CARE, V45, pE144, DOI 10.2337/dc22-1111
   Frykberg RG, 2021, MEDICINA-LITHUANIA, V57, DOI 10.3390/medicina57090917
   Frykberg RG, 2020, DIABETES CARE, V43, P616, DOI 10.2337/dc19-0476
   Frykberg RG, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3251
   Frykberg RG, 2015, ADV WOUND CARE, V4, P560, DOI 10.1089/wound.2015.0635
   Goodall RJ, 2020, EUR J VASC ENDOVASC, V60, P282, DOI 10.1016/j.ejvs.2020.03.053
   Gross JG, 2015, JAMA-J AM MED ASSOC, V314, P2137, DOI 10.1001/jama.2015.15217
   Gubitosi-Klug R, 2022, DIABETES CARE, V45, P1049, DOI 10.2337/dc21-1072
   Gubitosi-Klug RA, 2016, JAMA OPHTHALMOL, V134, P137, DOI 10.1001/jamaophthalmol.2015.4606
   Gunderson EP, 2007, DIABETES, V56, P2990, DOI 10.2337/db07-1024
   Gylfadottir SS, 2020, PAIN, V161, P574, DOI 10.1097/j.pain.0000000000001744
   Ha Joon, 2020, J Clin Orthop Trauma, V11, P357, DOI [10.1016/j.jcot.2020.03.025, 10.1016/j.jcot.2020.03.025]
   Hallaj S., Am J Ophthalmol
   Heng ML, 2020, INT WOUND J, V17, P1678, DOI 10.1111/iwj.13450
   Hernando-Garijo I, 2024, PHYSIOTHER THEOR PR, V40, P2116, DOI 10.1080/09593985.2023.2227975
   Hingorani A, 2016, J VASC SURG, V63, p3S, DOI 10.1016/j.jvs.2015.10.003
   Ismail-Beigi F, 2010, LANCET, V376, P419, DOI 10.1016/S0140-6736(10)60576-4
   Jaiswal M, 2015, J DIABETES COMPLICAT, V29, P1287, DOI 10.1016/j.jdiacomp.2015.07.013
   Jensen ET, 2023, DIABETES CARE, V46, P1252, DOI 10.2337/dc22-2503
   Jordan J, 2019, J HYPERTENS, V37, P1541, DOI 10.1097/HJH.0000000000002078
   Kataoka SY, 2023, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD013318.pub2
   La Fontaine J, 2014, INT J LOW EXTR WOUND, V13, P320, DOI 10.1177/1534734614555002
   Lalieu RC, 2020, WOUND REPAIR REGEN, V28, P266, DOI 10.1111/wrr.12776
   Lambert AP, 2003, DIABETES CARE, V26, P333, DOI 10.2337/diacare.26.2.333
   Löndahl M, 2010, DIABETES CARE, V33, P998, DOI 10.2337/dc09-1754
   Lu YH, 2020, FRONT PUBLIC HEALTH, V8, DOI 10.3389/fpubh.2020.534372
   Martin CL, 2014, DIABETES CARE, V37, P31, DOI 10.2337/dc13-2114
   Maturi RK, 2021, JAMA OPHTHALMOL, V139, P701, DOI 10.1001/jamaophthalmol.2021.0606
   McCallum RW, 2010, CLIN GASTROENTEROL H, V8, P947, DOI 10.1016/j.cgh.2010.05.020
   Mitchell P, 2011, OPHTHALMOLOGY, V118, P615, DOI 10.1016/j.ophtha.2011.01.031
   Nakayama LF, 2023, ANN MED, V55, DOI 10.1080/07853890.2023.2258149
   Nathan DM, 2017, NEW ENGL J MED, V376, P1507, DOI 10.1056/NEJMoa1612836
   Niazi S, 2024, OPHTHALMOLOGY, V131, P1056, DOI 10.1016/j.ophtha.2024.03.004
   Niederauer MQ, 2018, J WOUND CARE, V27, pS30, DOI 10.12968/jowc.2018.27.Sup9.S30
   Ntentakis DP, 2024, GRAEF ARCH CLIN EXP, V262, P717, DOI 10.1007/s00417-023-06236-5
   O'Brien PD, 2017, LANCET NEUROL, V16, P465, DOI 10.1016/S1474-4422(17)30084-4
   Obeid A, 2019, OPHTHALMOLOGY, V126, P407, DOI 10.1016/j.ophtha.2018.07.027
   Olausson EA, 2014, AM J GASTROENTEROL, V109, P375, DOI 10.1038/ajg.2013.453
   Parkman HP, 2011, GASTROENTEROLOGY, V141, P486, DOI 10.1053/j.gastro.2011.04.045
   Parrish CR., 2007, Diabetes Spectr, V20, P231, DOI DOI 10.2337/DIASPECT.20.4.231
   Peters A, 2017, DIABETOLOGIA, V60, P980, DOI 10.1007/s00125-017-4253-z
   Pham H, 2000, DIABETES CARE, V23, P606, DOI 10.2337/diacare.23.5.606
   Pinzur MS, 2023, J AM ACAD ORTHOP SUR, V31, P71, DOI 10.5435/JAAOS-D-22-00365
   Pontiroli AE, 2013, J SEX MED, V10, P1044, DOI 10.1111/jsm.12065
   Pop-Busui R, 2022, Diagnosis and treatment of painful diabetic peripheral neuropathy
   Pop-Busui R, 2017, DIABETES CARE, V40, P136, DOI 10.2337/dc16-2042
   Pop-Busui R, 2013, DIABETES CARE, V36, P3208, DOI 10.2337/dc13-0012
   Pop-Busui R, 2013, J AM COLL CARDIOL, V61, P447, DOI 10.1016/j.jacc.2012.10.028
   Pop-Busui R, 2010, DIABETES CARE, V33, P1578, DOI 10.2337/dc10-0125
   Pop-Busui R, 2009, CIRCULATION, V119, P2886, DOI 10.1161/CIRCULATIONAHA.108.837369
   Preiss D., 2024, NEJM Evid, V3, pEVIDoa2400179
   Price R, 2022, NEUROLOGY, V98, P31, DOI 10.1212/WNL.0000000000013038
   Raspovic KM, 2024, DIABETES-METAB RES, V40, DOI 10.1002/dmrr.3653
   Reaney M, 2022, APPL PSYCHOL-HLTH WE, V14, P465, DOI 10.1111/aphw.12314
   Rees G, 2016, JAMA OPHTHALMOL, V134, P1007, DOI 10.1001/jamaophthalmol.2016.2213
   Reiber GE, 1999, DIABETES CARE, V22, P157, DOI 10.2337/diacare.22.1.157
   Reynolds EL, 2023, DIABETOLOGIA, V66, P1192, DOI 10.1007/s00125-023-05899-3
   Rittiphairoj T, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD005656.pub3, 10.1002/14651858.00005656.pub3]
   Rogers LC, 2011, DIABETES CARE, V34, P2123, DOI 10.2337/dc11-0844
   Sacks FM, 2014, CIRCULATION, V129, P999, DOI 10.1161/CIRCULATIONAHA.113.002529
   Santema KTB, 2018, DIABETES CARE, V41, P112, DOI 10.2337/dc17-0654
   Schaper NC, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3266
   Serena TE, 2021, J WOUND CARE, V30, pS7, DOI 10.12968/jowc.2021.30.Sup5.S7
   Sethi A., 2022, Health Sci Rev, V3, P100028
   Shao SC, 2022, DIABETES METAB, V48, DOI 10.1016/j.diabet.2022.101318
   Sheehan P, 2003, DIABETES CARE, V26, P1879, DOI 10.2337/diacare.26.6.1879
   Silva PS, 2016, OPHTHALMOLOGY, V123, P1360, DOI 10.1016/j.ophtha.2016.01.043
   Sim Dawn A, 2016, J Diabetes Sci Technol, V10, P308, DOI [10.1177/1932296816629983, 10.1177/1932296816629983]
   Sivaprasad S, 2017, LANCET, V389, P2193, DOI 10.1016/S0140-6736(17)31193-5
   Smith AG, 2023, JAMA NEUROL, V80, P1334, DOI 10.1001/jamaneurol.2023.3711
   Solomon SD, 2017, DIABETES CARE, V40, P412, DOI 10.2337/dc16-2641
   Sterling J, 2023, BRIT J OPHTHALMOL, V107, P215, DOI 10.1136/bjophthalmol-2021-319232
   Stratton IM, 2001, DIABETOLOGIA, V44, P156, DOI 10.1007/s001250051594
   Streckmann F, 2022, SPORTS MED, V52, P1043, DOI 10.1007/s40279-021-01596-6
   Sun XK, 2022, INT WOUND J, V19, P2200, DOI 10.1111/iwj.13830
   Tang YL, 2021, DIABETES CARE, V44, P164, DOI 10.2337/dc20-1842
   Tesfaye S, 2022, LANCET, V400, P680, DOI 10.1016/S0140-6736(22)01472-6
   Turner RC, 1998, LANCET, V352, P837, DOI 10.1016/s0140-6736(98)07019-6
   Umpierrez G., 2014, Therapy for diabetes mellitus and related disorders
   van Netten JJ, 2016, DIABETES-METAB RES, V32, P84, DOI 10.1002/dmrr.2701
   Waldfogel JM, 2017, NEUROLOGY, V88, P1958, DOI 10.1212/WNL.0000000000003882
   Walton DV, 2021, J WOUND CARE, V30, P598, DOI 10.12968/jowc.2021.30.8.598
   Walton OB, 2016, JAMA OPHTHALMOL, V134, P204, DOI 10.1001/jamaophthalmol.2015.5083
   Wells JA, 2015, NEW ENGL J MED, V372, P1193, DOI 10.1056/NEJMoa1414264
   Widyaputri F, 2022, JAMA OPHTHALMOL, V140, P486, DOI 10.1001/jamaophthalmol.2022.0050
   Yammine K, 2020, INT J LOW EXTR WOUND, V19, P112, DOI 10.1177/1534734619888361
   Yau JWY, 2012, DIABETES CARE, V35, P556, DOI 10.2337/dc11-1909
   Yin L, 2020, MEDICINE, V99, DOI 10.1097/MD.0000000000019236
   Yoshida Y, 2022, J DIABETES COMPLICAT, V36, DOI 10.1016/j.jdiacomp.2022.108255
   Yuncken J, 2019, ENDOCRINE, V63, P660, DOI 10.1007/s12020-018-1821-z
   Zeng C, 2019, JAMA-J AM MED ASSOC, V321, P969, DOI 10.1001/jama.2019.1347
NR 137
TC 140
Z9 153
U1 10
U2 20
PU AMER DIABETES ASSOC
PI ALEXANDRIA
PA 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA
SN 0149-5992
EI 1935-5548
J9 DIABETES CARE
JI Diabetes Care
PD JAN
PY 2025
VL 48
SU 1
BP S252
EP S265
DI 10.2337/dc25-S012
PG 14
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA P5J9Q
UT WOS:001378283000004
PM 39651973
OA Green Submitted, Bronze
HC Y
HP Y
DA 2026-07-24
ER

PT J
AU Ginting, N
   Tremblay, L
   Kortbeek, JB
AF Ginting, Nadra
   Tremblay, Lorraine
   Kortbeek, J. B.
TI Surgisis® in the management of the complex abdominal wall in trauma: A
   case series and review of the literature
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Review
DE Small intestinal submucosa; Abdominal wall trauma; Hernia; Abdominal;
   Surgical mesh; Wounds and injuries
ID SMALL-INTESTINAL SUBMUCOSA; TRIAL COMPARING POLYGLACTIN-910-MESH;
   VACUUM-ASSISTED CLOSURE; SHORT-TERM OUTCOMES; PROSTHETIC MATERIAL;
   HERNIA; REPAIR
AB Managing complex abdominal wall injuries acutely or at the time of reconstruction is challenging. Contaminated surgical fields, devitalized tissue, intestinal fistula and tissues under tension contribute to clinical scenarios where closure is not possible or morbidity is unacceptable. The introduction of an absorbable extracellular matrix derived from porcine small intestinal submucosa (Surgisis (R)) adds a potentially useful tool to the surgeon's armamentarium. A retrospective case series of the initial experience in 5 patients with complex abdominal wall injury following trauma managed with Surgisis (R) is described. A review of the literature describing the use of Surgisis (R) in contaminated fields is also performed. (C) 2010 Elsevier Ltd. All rights reserved.
C1 [Kortbeek, J. B.] Univ Calgary, Foothills Med Ctr, Dept Surg, Calgary, AB T2N 2T9, Canada.
   [Tremblay, Lorraine] Univ Toronto, Sunnybrook Med Ctr, Dept Surg, Toronto, ON M5S 1A1, Canada.
   [Tremblay, Lorraine] Univ Toronto, Sunnybrook Med Ctr, Dept Crit Care, Toronto, ON M5S 1A1, Canada.
   [Kortbeek, J. B.] Univ Calgary, Dept Crit Care, Calgary, AB T2N 2T9, Canada.
C3 University of Calgary; University Calgary Hospital; University of
   Toronto; Sunnybrook Health Science Center; Sunnybrook Research
   Institute; University of Toronto; Sunnybrook Health Science Center;
   Sunnybrook Research Institute; University of Calgary
RP Kortbeek, JB (通讯作者)，Univ Calgary, Foothills Med Ctr, Dept Surg, 1403-29st NW, Calgary, AB T2N 2T9, Canada.
EM John.Kortbeek@AlbertaHealthServices.ca
RI Kortbeek, John/AAO-5298-2020
CR Baillie DR, 2007, OSTOMY WOUND MANAG, V53, P30
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   Celso B, 2006, J TRAUMA, V60, P371, DOI 10.1097/01.ta.0000197916.99629.eb
   Franklin ME, 2008, SURG ENDOSC, V22, P1941, DOI 10.1007/s00464-008-0005-y
   Gruen RL, 2006, ANN SURG, V244, P371, DOI 10.1097/01.sla.0000234655.83517.56
   Gupta A, 2006, Hernia, V10, P419, DOI 10.1007/s10029-006-0130-2
   Helton WS, 2005, ARCH SURG-CHICAGO, V140, P549, DOI 10.1001/archsurg.140.6.549
   Hodde J, 2002, BIOTECHNOL BIOENG, V79, P211, DOI 10.1002/bit.10281
   Johnson EK, 2007, MIL MED, V172, P1119, DOI 10.7205/MILMED.172.10.1119
   Kortbeek JB, 2008, J TRAUMA, V64, P1638, DOI 10.1097/TA.0b013e3181744b03
   Landercasper J, 2005, ARCH SURG-CHICAGO, V140, P560
   Pu LLQ, 2005, PLAST RECONSTR SURG, V115, P2127, DOI 10.1097/01.PRS.0000168883.65715.2F
   Tinkoff G, 2008, J TRAUMA, V65, P342
   Ueno T, 2004, J GASTROINTEST SURG, V8, P109, DOI 10.1016/j.gassur.2003.09.025
NR 14
TC 9
Z9 9
U1 0
U2 9
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0020-1383
J9 INJURY
JI Injury-Int. J. Care Inj.
PD SEP
PY 2010
VL 41
IS 9
BP 970
EP 973
DI 10.1016/j.injury.2010.01.099
PG 4
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA 634SL
UT WOS:000280605500018
PM 20181333
DA 2026-07-24
ER

PT J
AU Milias, K
   Deligiannidis, N
   Papavramidis, TS
   Ioannidis, K
   Xiros, N
   Papavramidis, S
AF Milias, Konstantinos
   Deligiannidis, Nikolaos
   Papavramidis, Theodossis S.
   Ioannidis, Konstantinos
   Xiros, Nikolaos
   Papavramidis, Spiros
TI Biliogastric Diversion for the Management of High-Output Duodenal
   Fistula: Report of Two Cases and Literature Review
SO JOURNAL OF GASTROINTESTINAL SURGERY
LA English
DT Review
DE Duodenal fistula; Duodenal perforation; Duodenal wall defect; Endoscopic
   sphincterotomy; Biliogastric diversion; Pylorus preservation
ID VACUUM-ASSISTED CLOSURE; ENTEROCUTANEOUS FISTULA; GASTROINTESTINAL
   FISTULAS; SURGICAL-MANAGEMENT; PYLORIC EXCLUSION; ENDOSCOPIC TREATMENT;
   INJURIES; SURGERY; OCTREOTIDE; NUTRITION
AB High-output duodenal fistula occurs as a result of a duodenal wall defect caused by gastroduodenal surgery, endoscopic sphincterotomy, duodenal injury, and tumors with high morbidity and mortality rate. A new technique for its management is reported along with literature review. This procedure consists of transection of the duodenum 2 cm distally to the pylorus, transection of the common bile duct, and end duodenostomy with or without suturing the duodenal wall defect. The continuity of the alimentary tract is reinstated by an end-to-end duodenojejunostomy, end-to-side choledochojejunostomy, and end-to-side Roux-en-Y jejunojejunostomy, obtaining biliogastric diversion from the duodenum and closure of the fistula. This technique was performed in two patients with excellent results.
C1 [Milias, Konstantinos] 424 Gen Mil Hosp, Dept Surg 2, Thessaloniki, Greece.
   [Deligiannidis, Nikolaos; Papavramidis, Theodossis S.; Papavramidis, Spiros] AHEPA Univ Hosp, Surg Dept 3, Thessaloniki, Greece.
   [Ioannidis, Konstantinos] 424 Gen Mil Hosp, Dept Surg 1, Thessaloniki, Greece.
   [Xiros, Nikolaos] 404 Gen Mil Hosp, Dept Surg, Larisa, Greece.
C3 Aristotle University of Thessaloniki; Ahepa University Hospital
RP Milias, K (通讯作者)，424 Gen Mil Hosp, Dept Surg 2, Thessaloniki, Greece.
EM konmil@med.auth.gr
RI Papavramidis, Theodossis/E-8260-2011; Papavramidis,
   Theodossis/E-8260-2011
OI Papavramidis, Theodossis/0000-0002-7097-9889; Papavramidis,
   Theodossis/0000-0002-7097-9889
CR Alvarez AA, 2001, GYNECOL ONCOL, V80, P413, DOI 10.1006/gyno.2000.6092
   Alvarez C, 2000, WORLD J SURG, V24, P533, DOI 10.1007/s002689910086
   Androulakis J, 2000, SURG CLIN N AM, V80, P171, DOI 10.1016/S0039-6109(05)70401-1
   Asensio J A, 1993, Curr Probl Surg, V30, P1023
   Asensio JA, 1997, AM J SURG, V174, P54, DOI 10.1016/S0002-9610(97)00029-9
   Astarcioglu H, 2001, AM J SURG, V181, P309, DOI 10.1016/S0002-9610(01)00586-4
   BRADY AP, 1995, RADIOLOGY, V196, P573, DOI 10.1148/radiology.196.2.7617880
   CADONI S, 1990, ENDOSCOPY, V22, P194, DOI 10.1055/s-2007-1012841
   Chander J, 2004, WORLD J SURG, V28, P179, DOI 10.1007/s00268-003-7017-5
   Chung MA, 1996, SURG CLIN N AM, V76, P1137, DOI 10.1016/S0039-6109(05)70502-8
   Clendenon JN, 2004, J PEDIATR SURG, V39, P964, DOI 10.1016/j.jpedsurg.2004.02.032
   CORLEY RD, 1975, ANN SURG, V181, P92, DOI 10.1097/00000658-197501000-00020
   DADOUKIS JD, 1993, EUR J SURG, V159, P31
   DEGIANNIS E, 1993, WORLD J SURG, V17, P751, DOI 10.1007/BF01659085
   Draus JM, 2006, SURGERY, V140, P570, DOI 10.1016/j.surg.2006.07.003
   Dudrick SJ, 1999, WORLD J SURG, V23, P570, DOI 10.1007/PL00012349
   Erdmann D, 2001, PLAST RECONSTR SURG, V108, P2066, DOI 10.1097/00006534-200112000-00036
   Evenson AR, 2006, J GASTROINTEST SURG, V10, P455, DOI 10.1016/j.gassur.2005.08.001
   FAZIO VW, 1983, WORLD J SURG, V7, P481, DOI 10.1007/BF01655937
   FELICIANO DV, 1987, ANN SURG, V205, P673, DOI 10.1097/00000658-198706000-00009
   Foster CE, 1996, SURG CLIN N AM, V76, P1019, DOI 10.1016/S0039-6109(05)70496-5
   GARDEN OJ, 1988, DIGEST DIS SCI, V33, P30, DOI 10.1007/BF01536627
   Hernandez-Aranda J C, 1996, Nutr Hosp, V11, P226
   HESSE U, 2001, GUT S4, V49, P11
   Hollington P, 2004, BRIT J SURG, V91, P1646, DOI 10.1002/bjs.4788
   Ishiguro S, 2004, SURG TODAY, V34, P386, DOI 10.1007/s00595-003-2717-x
   IVATURY RR, 1985, ANN SURG, V202, P153, DOI 10.1097/00000658-198508000-00003
   Katsinelos P, 2005, WORLD J GASTROENTERO, V11, P6232, DOI 10.3748/wjg.v11.i39.6232
   Khairy GEA, 2000, J ROY COLL SURG EDIN, V45, P342
   Ladd AP, 2002, SURGERY, V132, P748, DOI 10.1067/msy.2002.127673
   Leppaniemi A., 2007, LIETUVOS CHIRURGIJA, V5, P102
   LEVY E, 1984, BRIT J SURG, V71, P543, DOI 10.1002/bjs.1800710725
   Lloyd DAJ, 2006, BRIT J SURG, V93, P1045, DOI 10.1002/bjs.5396
   Papavramidis ST, 2004, GASTROINTEST ENDOSC, V59, P296, DOI 10.1016/S0016-5107(03)02545-8
   REBER HA, 1978, ANN SURG, V188, P460, DOI 10.1097/00000658-197810000-00003
   ROSSI JA, 1986, ARCH SURG-CHICAGO, V121, P908
   SANCHO JJ, 1995, BRIT J SURG, V82, P638, DOI 10.1002/bjs.1800820521
   SCHEIN M, 1991, AM J SURG, V161, P435, DOI 10.1016/0002-9610(91)91107-T
   Seamon MJ, 2007, J TRAUMA, V62, P829, DOI 10.1097/TA.0b013e318033a790
   SHORR RM, 1987, AM J SURG, V154, P93, DOI 10.1016/0002-9610(87)90296-0
   SITGESSERRA A, 1982, BRIT J SURG, V69, P147, DOI 10.1002/bjs.1800690310
   STAWICKI SP, 2008, OPUS 12 SCI, V2, P14
   Talving P, 2006, WORLD J SURG, V30, P488, DOI 10.1007/s00268-005-0245-0
   Truong S, 2004, SURG ENDOSC, V18, P1105, DOI 10.1007/s00464-003-8286-7
   UJIKI GT, 1981, ARCH SURG-CHICAGO, V116, P614
   VAUGHAN GD, 1977, AM J SURG, V134, P785, DOI 10.1016/0002-9610(77)90325-7
   Verma G R, 2006, Indian J Gastroenterol, V25, P16
   Williams NMA, 1997, AM J SURG, V173, P240, DOI 10.1016/S0002-9610(97)89600-6
   Wong SKH, 2000, ENDOSCOPY, V32, P311, DOI 10.1055/s-2000-7378
   Yamamoto T, 1998, DIS COLON RECTUM, V41, P1287, DOI 10.1007/BF02258230
   YSEBAERT D, 1994, SCAND J GASTROENTERO, V29, P42, DOI 10.3109/00365529409104194
   Zarzour JG, 2008, J GASTROINTEST SURG, V12, P1103, DOI 10.1007/s11605-007-0456-9
NR 52
TC 14
Z9 16
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1091-255X
EI 1873-4626
J9 J GASTROINTEST SURG
JI J. Gastrointest. Surg.
PD FEB
PY 2009
VL 13
IS 2
BP 299
EP 303
DI 10.1007/s11605-008-0677-6
PG 5
WC Gastroenterology & Hepatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology; Surgery
GA 402AU
UT WOS:000262987400019
PM 18825468
DA 2026-07-24
ER

PT J
AU Firat, C
   Aytekin, AH
   Erbatur, S
AF Firat, Cemal
   Aytekin, Ahmet Hamdi
   Erbatur, Serkan
TI Management of Composite Tissue Defect of the Midfoot With a Free
   Anterolateral Thigh Flap and Iliac Bone Graft: A Case Report
SO JOURNAL OF FOOT & ANKLE SURGERY
LA English
DT Article
DE ALT fasciocutaneous flap; bone reconstructive surgery; bone
   scintigraphy; vacuum-assisted closure
ID OPEN TIBIAL FRACTURES; VASCULARIZED FIBULAR GRAFTS; SOFT-TISSUE;
   LOWER-EXTREMITY; EXTERNAL FIXATION; RECONSTRUCTION; MUSCLE; EXPERIENCE;
   FOOT
AB Composite tissue defects of the midfoot with extensive bone and soft tissue loss represent a unique challenge because they can lead to primary amputation if not reconstructed. One should repair both the bone structure and the soft tissue to obtain satisfactory foot function for basic daily activities. In the present study, we report on a case in which we successfully reconstructed an extensive midfoot defect with iliac bone grafts for metatarsal reconstruction and an anterolateral thigh flap for soft tissue coverage. This technique is a safe, reliable, and functional method, offering single-stage reconstruction compared with other microsurgical techniques used for such defects. (C) 2016 by the American College of Foot and Ankle Surgeons. All rights reserved.
C1 [Firat, Cemal; Aytekin, Ahmet Hamdi] Inonu Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-44280 Malatya, Turkey.
   [Erbatur, Serkan] Dicle Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, Diyarbakir, Turkey.
C3 Inonu University; Dicle University
RP Aytekin, AH (通讯作者)，Inonu Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-44280 Malatya, Turkey.
EM ahaytekin@gmail.com
RI Erbatur, Serkan/LZH-1943-2025; Fırat, Cemal/D-1292-2012
OI Fırat, Cemal/0000-0003-2051-6410
CR BEHRENS F, 1983, CLIN ORTHOP RELAT R, P111
   BLICK SS, 1989, CLIN ORTHOP RELAT R, P21
   Bowers KW, 2000, J BONE JOINT SURG AM, V82A, P694, DOI 10.2106/00004623-200005000-00010
   BROWN KLB, 1991, CLIN ORTHOP RELAT R, P64
   BROWN PW, 1973, CLIN ORTHOP RELAT R, P42
   BYRD HS, 1985, PLAST RECONSTR SURG, V76, P719, DOI 10.1097/00006534-198511000-00011
   CHAN KM, 1984, INJURY, V16, P157, DOI 10.1016/0020-1383(84)90152-9
   CHRISTIAN EP, 1989, J BONE JOINT SURG AM, V71A, P994, DOI 10.2106/00004623-198971070-00006
   CIERNY G, 1983, CLIN ORTHOP RELAT R, P54
   Clements JR, 2012, J FOOT ANKLE SURG, V51, P118, DOI 10.1053/j.jfas.2011.10.022
   COURTBROWN CM, 1990, J BONE JOINT SURG BR, V72, P801, DOI 10.1302/0301-620X.72B5.2211760
   DAGHER F, 1991, J BONE JOINT SURG BR, V73, P316, DOI 10.1302/0301-620X.73B2.2005164
   Doi K, 1995, MICROSURG, V16, P704, DOI 10.1002/micr.1920161009
   Gomez MM, 2012, J FOOT ANKLE SURG, V51, P215, DOI 10.1053/j.jfas.2011.07.008
   GREEN SA, 1983, CLIN ORTHOP RELAT R, P117
   Greene T L, 1988, J Orthop Trauma, V2, P158
   KOJIMA T, 1979, J TRAUMA, V19, P724, DOI 10.1097/00005373-197910000-00002
   Lin CH, 1997, PLAST RECONSTR SURG, V99, P1656, DOI 10.1097/00006534-199705010-00028
   Mackenzie DJ, 2006, PLASTIC SURG, P1355
   Minami A, 2000, J BONE JOINT SURG BR, V82B, P1022, DOI 10.1302/0301-620X.82B7.10332
   Ong YS, 2010, PLAST RECONSTR SURG, V125, P582, DOI 10.1097/PRS.0b013e3181c82ed1
   SWARTZ WM, 1986, CLIN PLAST SURG, V13, P633
   Wettstein R, 2008, J PLAST RECONSTR AES, V61, P772, DOI 10.1016/j.bjps.2007.11.037
   Yamashita Y, 2013, J PLAST RECONSTR AES, V66, P277, DOI 10.1016/j.bjps.2012.07.029
   YAREMCHUK MJ, 1987, PLAST RECONSTR SURG, V80, P1
   Yazar S, 2004, PLAST RECONSTR SURG, V114, P1457, DOI 10.1097/01.PRS.0000138811.88807.65
   Zhu YL, 2013, MICROSURG, V33, P600, DOI 10.1002/micr.22177
NR 27
TC 2
Z9 2
U1 0
U2 2
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1067-2516
EI 1542-2224
J9 J FOOT ANKLE SURG
JI J. Foot Ankle Surg.
PD MAR-APR
PY 2016
VL 55
IS 2
BP 263
EP 266
DI 10.1053/j.jfas.2014.06.021
PG 4
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA DE5FV
UT WOS:000370657600011
PM 25128303
DA 2026-07-24
ER

PT J
AU Massara, M
   Barillà, D
   De Caridi, G
   Serra, R
   Volpe, A
   Surace, R
   Foti, G
   Marcuccio, D
   Pucci, G
   Volpe, P
AF Massara, Mafalda
   Barilla, David
   De Caridi, Giovanni
   Serra, Raffaele
   Volpe, Alberto
   Surace, Rosangela
   Foti, Giovanni
   Marcuccio, Daniela
   Pucci, Giulia
   Volpe, Pietro
TI Application of autologous platelet-rich plasma to enhance wound healing
   after lower limb revascularization: A case series and literature review
SO SEMINARS IN VASCULAR SURGERY
LA English
DT Review
ID FIBROBLAST-GROWTH-FACTOR; THERAPEUTIC ANGIOGENESIS; FOOT ULCERS; GEL;
   ISCHEMIA; CELLS; STIMULATION; RECRUITMENT; DELIVERY; BB
AB Dermal tissue loss in patients affected by critical limb ischemia represents a serious wound-healing problem, with high morbidity, prolonged hospital stay, and high patient care costs. Treatment of ischemic foot lesions requires limb revascularization by endovascular or open surgical intervention and individualized patient-specific wound care, including antibiotic therapy; devitalized/infected wound debridement; and advanced wound dressing. In selected patients, spinal cord stimulation, vacuum-assisted closure therapy, and bioengineered tissue or skin substitutes and growth factors have been shown to improve wound healing. In this study, we present our preliminary results on topical application of autologous platelet-rich plasma to enhance the process of wound healing after revascularization of lower limbs in patients affected by critical limb ischemia. (C) 2016 Elsevier Inc. All rights reserved.
C1 [Massara, Mafalda; Barilla, David; Volpe, Pietro] Bianchi Melacrino Morelli Hosp, Unit Vasc Surg, Via Melacrino 1, I-89100 Reggio Di Calabria, Italy.
   [Massara, Mafalda; De Caridi, Giovanni] Univ Messina, Policlin G Martino Hosp, Cardiovasc & Thorac Dept, Messina, Italy.
   [Serra, Raffaele] Magna Graecia Univ Catanzaro, Dept Surg & Med Sci, Catanzaro, Italy.
   [Serra, Raffaele] Magna Graecia Univ Catanzaro, Interuniv Ctr Phlebolymphol CIFL, Int Res & Educ Program Clin & Expt Biotechnol, Catanzaro, Italy.
   [Volpe, Alberto] Univ Campus Biomed Rome, Rome, Italy.
   [Surace, Rosangela; Foti, Giovanni; Marcuccio, Daniela; Pucci, Giulia] Bianchi Melacrino Morelli Hosp, Calabria Cord Blood Bank, Serv Immunohaematol & Transfus Med, Reggio Di Calabria, Italy.
C3 University of Messina; University Messina Policlin; Magna Graecia
   University of Catanzaro; Magna Graecia University of Catanzaro;
   University Campus Bio-Medico - Rome Italy
RP Massara, M (通讯作者)，Bianchi Melacrino Morelli Hosp, Unit Vasc Surg, Via Melacrino 1, I-89100 Reggio Di Calabria, Italy.; Massara, M (通讯作者)，Univ Messina, Policlin G Martino Hosp, Cardiovasc & Thorac Dept, Messina, Italy.
EM drmafaldamassara@gmail.com
RI BARILLA', David/JXN-4900-2024; De Caridi, Giovanni/KRQ-6363-2024; Serra,
   Raffaele/AAA-6874-2022; /AAM-9453-2020
OI BARILLA', David/0000-0002-4675-7901; De Caridi,
   Giovanni/0000-0002-1859-9010; Serra, Raffaele/0000-0003-4477-7412; 
CR [Anonymous], GUID MAN WOUNDS PAT
   ASAHARA T, 1995, CIRCULATION, V92, P365, DOI 10.1161/01.CIR.92.9.365
   Cao RH, 2003, NAT MED, V9, P604, DOI 10.1038/nm848
   Carmeliet P, 2003, NAT MED, V9, P653, DOI 10.1038/nm0603-653
   Ceradini DJ, 2004, NAT MED, V10, P858, DOI 10.1038/nm1075
   De Caridi G, 2014, INT WOUND J
   De Caridi G, 2016, INT WOUND J, V13, P72, DOI 10.1111/iwj.12233
   De Caridi G, 2016, INT WOUND J, V13, P97, DOI 10.1111/iwj.12241
   De Falco E, 2004, BLOOD, V104, P3472, DOI 10.1182/blood-2003-12-4423
   Driver VR, 2006, OSTOMY WOUND MANAG, V52, P68
   Ferrara N, 2001, ACTA HAEMATOL-BASEL, V106, P148, DOI 10.1159/000046610
   Frykberg RG, 2010, OSTOMY WOUND MANAG, V56, P36
   Hashimoto T, 2009, EUR J VASC ENDOVASC, V38, P71, DOI 10.1016/j.ejvs.2009.02.005
   He Li-Ping, 2012, Sichuan Da Xue Xue Bao Yi Xue Ban, V43, P757
   Iesari S, 2015, EXP CLIN TRANSPLANT
   Kang HJ, 2004, LANCET, V363, P751, DOI 10.1016/S0140-6736(04)15689-4
   Kontopodis N, 2015, INT J LOW EXTREM WOU
   Kurita J, 2011, ANN THORAC SURG, V92, P837, DOI 10.1016/j.athoracsur.2011.04.084
   Layman H, 2009, ACTA BIOMATER, V5, P230, DOI 10.1016/j.actbio.2008.07.024
   Li Lan, 2012, Sichuan Da Xue Xue Bao Yi Xue Ban, V43, P762
   Man D, 2001, PLAST RECONSTR SURG, V107, P229, DOI 10.1097/00006534-200101000-00037
   Mannari RJ, 2002, WOUNDS, V14, P116
   Marui A, 2005, J VASC SURG, V41, P82, DOI 10.1016/j.jvs.2004.10.029
   Marx R E, 2001, Implant Dent, V10, P225
   Marx RE, 2004, J ORAL MAXIL SURG, V62, P489, DOI 10.1016/j.joms.2003.12.003
   Marx RE, 1998, ORAL SURG ORAL MED O, V85, P638, DOI 10.1016/S1079-2104(98)90029-4
   Pinto JMN, 2014, AN BRAS DERMATOL, V89, P638
   Norgren L, 2007, J VASC SURG, V45, pS5, DOI 10.1016/j.jvs.2006.12.037
   Ouma GO, 2013, ANGIOLOGY, V64, P466, DOI 10.1177/0003319712464514
   Peters EJ, 2001, ARCH PHYS MED REHAB, V82, P721, DOI 10.1053/apmr.2001.23780
   Serra R, 2015, INT WOUND J, V12, P555, DOI 10.1111/iwj.12162
   Serra R, 2013, INT WOUND J, V10, P612, DOI 10.1111/iwj.12052
   Serra R, 2013, WOUND REPAIR REGEN, V21, P395, DOI 10.1111/wrr.12035
   Stellos K, 2008, CIRCULATION, V117, P206, DOI 10.1161/CIRCULATIONAHA.107.714691
   Tateishi-Yuyama E, 2002, LANCET, V360, P427, DOI 10.1016/S0140-6736(02)09670-8
   Tzeng YS, 2013, BIOMED RES INT, V2013, DOI 10.1155/2013/837620
   Veves A, 2001, DIABETES CARE, V24, P290, DOI 10.2337/diacare.24.2.290
   Yamada T, 2013, INT J VASC MED, V2013, DOI 10.1155/2013/437471
   Yamaguchi J, 2003, CIRCULATION, V107, P1322, DOI 10.1161/01.CIR.0000055313.77510.22
   Yotsu RR, 2015, J DERMATOL, V42, P288, DOI 10.1111/1346-8138.12777
NR 40
TC 12
Z9 16
U1 1
U2 3
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0895-7967
EI 1558-4518
J9 SEMIN VASC SURG
JI Semin. Vasc. Surg.
PD SEP-DEC
PY 2015
VL 28
IS 3-4
BP 195
EP 200
DI 10.1053/j.semvascsurg.2016.01.002
PG 6
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA DL3DL
UT WOS:000375514300008
PM 27113287
DA 2026-07-24
ER

PT J
AU Rocco, G
   Mori, S
   Fazioli, F
   La Rocca, A
   Martucci, N
   Setola, S
AF Rocco, Gaetano
   Mori, Stefano
   Fazioli, Flavio
   La Rocca, Antonello
   Martucci, Nicola
   Setola, Sergio
TI The Use of Biomaterials for Chest Wall Reconstruction 30 Years After
   Radical Surgery and Radiation
SO ANNALS OF THORACIC SURGERY
LA English
DT Editorial Material
ID TITANIUM PLATES; COMBINATION
AB The combination of titanium plates and acellular collagen matrix was used to restore anterior chest wall integrity in a 68-year-old woman more than 30 years after a Halsted mastectomy and radiation treatment. A vertical rectus abdominis muscle flap was used for myocutaneous coverage of the reconstructed chest wall. Partial necrosis of the flap caused prolonged exposure of the collagen matrix and the titanium plates, which were then covered with a free skin graft. Long-term results were satisfactory despite continued infection treated with vacuum-assisted closure and surgical debridement. Recently introduced materials for chest wall reconstruction may offer resilience to infection, tolerability, and stability, and their use may be contemplated when the potential for local morbidity is high. (Ann Thorac Surg 2012;94:e109-10) (C) 2012 by The Society of Thoracic Surgeons
C1 [Rocco, Gaetano] Pascale Fdn, Natl Canc Inst, Dept Thorac Surg & Oncol, Div Thorac Surg,Serv Reconstruct Surg,Serv Orthop, I-80131 Naples, Italy.
   Pascale Fdn, Natl Canc Inst, Dept Radiodiagnost, I-80131 Naples, Italy.
C3 IRCCS Fondazione Pascale; IRCCS Fondazione Pascale
RP Rocco, G (通讯作者)，Pascale Fdn, Natl Canc Inst, Dept Thorac Surg & Oncol, Div Thorac Surg,Serv Reconstruct Surg,Serv Orthop, Via Semmola 81, I-80131 Naples, Italy.
EM gaetano.rocco@btopenworld.com
RI ; Rocco, Gaetano/K-4801-2016
OI FAZIOLI, FLAVIO/0000-0002-4308-1192; Rocco, Gaetano/0000-0003-4150-8604;
   Setola, Sergio Venanzio/0000-0002-9922-4033
CR Berthet JP, 2011, ANN THORAC SURG, V91, P1709, DOI 10.1016/j.athoracsur.2011.02.014
   Iarussi T, 2010, J THORAC CARDIOV SUR, V140, P476, DOI 10.1016/j.jtcvs.2009.07.030
   Lee TY, 2007, ANN THORAC SURG, V84, P664, DOI 10.1016/j.athoracsur.2007.03.006
   Rocco G, 2007, J THORAC CARDIOV SUR, V133, P1112, DOI 10.1016/j.jtcvs.2006.11.045
   Rocco G, 2011, SEMIN THORAC CARDIOV, V23, P307, DOI 10.1053/j.semtcvs.2012.01.011
   Rocco G, 2011, ANN THORAC SURG, V92, pE17, DOI 10.1016/j.athoracsur.2011.02.080
   Rocco G, 2011, J THORAC CARDIOV SUR, V141, P839, DOI 10.1016/j.jtcvs.2010.06.050
   Rocco G, 2010, ANN THORAC SURG, V90, pE14, DOI 10.1016/j.athoracsur.2010.04.071
NR 8
TC 15
Z9 18
U1 0
U2 7
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0003-4975
J9 ANN THORAC SURG
JI Ann. Thorac. Surg.
PD OCT
PY 2012
VL 94
IS 4
BP E109
EP E110
DI 10.1016/j.athoracsur.2012.08.029
PG 2
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA 016OJ
UT WOS:000309528300010
PM 23006719
OA Bronze
DA 2026-07-24
ER

PT J
AU Agha, R
   Ogawa, R
   Pietramaggiori, G
   Orgill, DP
AF Agha, Riaz
   Ogawa, Rei
   Pietramaggiori, Giorgio
   Orgill, Dennis P.
TI A Review of the Role of Mechanical Forces in Cutaneous Wound Healing
SO JOURNAL OF SURGICAL RESEARCH
LA English
DT Review
DE cutaneous; wound healing; micromechanical forces; angiogenesis; VAC;
   keloid hypertrophic scarring; wound tension
ID VACUUM-ASSISTED CLOSURE; RED DUROC PIG; HYPERTROPHIC SCAR FORMATION;
   SMOOTH-MUSCLE-CELLS; SILICONE GEL SHEETS; SKIN WOUNDS; IN-VITRO;
   EXTRACELLULAR-MATRIX; HEMODYNAMIC FORCES; VASCULAR-RESPONSES
AB Cutaneous wound healing is a complex process with many types of mechanical forces regulating the quality and speed of healing. The role of mechanical forces in regulating tissue growth, repair and remodelling was recognised more than a century ago. Such forces influence gene expression, the synthesis of growth factors and inflammatory mediators and cellular processes like proliferation of many load-sensitive cells. However, the exact mechanisms by which these forces interact with cells and ways to use them to stimulate tissues are still active research fronts. This article sets to review the literature on mechanical forces and their role in cutaneous wound healing. (C) 2011 Elsevier Inc. All rights reserved.
C1 [Agha, Riaz] Cambridge Univ Hosp NHS Fdn Trust, Dept Vasc Surg, Natl Inst Hlth & Clin Excellence Scholar, Cambridge, England.
   [Ogawa, Rei] Nippon Med Sch, Bunkyo Ku, Tokyo 113, Japan.
   [Pietramaggiori, Giorgio] Univ Geneva, Div Plast Surg, Geneva, Switzerland.
   [Orgill, Dennis P.] Brigham & Womens Hosp, Dept Surg, Div Plast Surg, Boston, MA 02115 USA.
   [Orgill, Dennis P.] Harvard Univ, Sch Med, Boston, MA USA.
C3 National Institute for Health & Care Excellence; University of
   Cambridge; Nippon Medical School; University of Geneva; Harvard
   University; Harvard University Medical Affiliates; Brigham & Women's
   Hospital; Harvard University; Harvard Medical School
RP Agha, R (通讯作者)，Queen Victoria Hosp NHS Fdn Trust, Dept Plast Surg, Holtye Rd, E Grinstead RH19 3DZ, W Sussex, England.
EM mail@riazagha.com
RI Agha, Riaz/KLC-2726-2024; Orgill, Dennis/H-7596-2019; PIETRAMAGGIORI,
   Giorgio/HJA-1920-2022
OI Agha, Riaz/0000-0002-9348-0095; Orgill, Dennis/0000-0002-8279-7310; 
CR Aarabi S, 2007, FASEB J, V21, P3250, DOI 10.1096/fj.07-8218com
   Agha RA, 2006, CLIN ANAT, V19, P115, DOI 10.1002/ca.20197
   Agha Riaz, 2005, Int J Surg, V3, P263, DOI 10.1016/j.ijsu.2005.10.001
   Akaishi S, 2008, ANN PLAS SURG, V60, P445, DOI 10.1097/SAP.0b013e3181238dd7
   Akaishi S, 2008, MED HYPOTHESES, V71, P32, DOI 10.1016/j.mehy.2008.01.032
   Akaishi S, 2010, PLAST RECONSTR SURG, V126, p109E, DOI 10.1097/PRS.0b013e3181df7073
   [Anonymous], 1978, BR J PLAST SURG, V31, P185
   [Anonymous], LAW BONE REMODELING
   [Anonymous], PLASTISCHE CHIRURG
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Atkinson JAM, 2005, PLAST RECONSTR SURG, V116, P1648, DOI 10.1097/01.prs.0000187147.73963.a5
   Beeson M, 2003, DIABETES, V52, P1926, DOI 10.2337/diabetes.52.8.1926
   Borgognoni L, 2002, WOUND REPAIR REGEN, V10, P118, DOI 10.1046/j.1524-475X.2002.00205.x
   Bouffard NA, 2008, J CELL PHYSIOL, V214, P389, DOI 10.1002/jcp.21209
   Buravkova LB, 2001, ACTA ASTRONAUT, V48, P647, DOI 10.1016/S0094-5765(01)00023-6
   BURRINGTON JD, 1971, J PEDIATR SURG, V6, P523, DOI 10.1016/0022-3468(71)90373-3
   Cass DL, 1997, J PEDIATR SURG, V32, P411, DOI 10.1016/S0022-3468(97)90593-5
   Chan RK, 2007, PLAST RECONSTR SURG, V120, P409, DOI 10.1097/01.prs.0000267696.98789.66
   Chang CC, 1995, J SURG RES, V59, P705, DOI 10.1006/jsre.1995.1227
   Chen CS, 1997, SCIENCE, V276, P1425, DOI 10.1126/science.276.5317.1425
   Chen LW, 2008, PLOS ONE, V3, DOI 10.1371/journal.pone.0001886
   Chin MS, 2009, PLAST RECONSTR SURG, V124, P102, DOI 10.1097/PRS.0b013e3181a81542
   Chu EK, 2005, AM J RESP CELL MOL, V32, P373, DOI 10.1165/rcmb.2004-0266OC
   Chu EK, 2006, AM J RESP CELL MOL, V35, P628, DOI 10.1165/rcmb.2006-0040OC
   Colwell AS, 2008, WOUND REPAIR REGEN, V16, P450, DOI 10.1111/j.1524-475X.2008.00383.x
   Colwell AS, 2005, ADV BIOCHEM ENG BIOT, V93, P83, DOI 10.1007/b99972
   Colwell AS, 2003, FRONT BIOSCI-LANDMRK, V8, pS1240, DOI 10.2741/1183
   COUCHMAN JR, 1990, J INVEST DERMATOL, V94, pS7, DOI 10.1111/1523-1747.ep12874973
   Cummings G S., 1992, Dynamics of human biologic tissues Contemporary perspectives in rehabilitation
   Cunningham KS, 2005, LAB INVEST, V85, P9, DOI 10.1038/labinvest.3700215
   DAVIES PF, 1986, P NATL ACAD SCI USA, V83, P2114, DOI 10.1073/pnas.83.7.2114
   Daya M, 2008, PLAST RECONSTR SURG, V122, P1047, DOI 10.1097/PRS.0b013e3181858c68
   Denda M, 2007, EXP DERMATOL, V16, P157, DOI 10.1111/j.1600-0625.2006.00529.x
   Edwards Sharon L, 2006, Nurs Stand, V21, P48
   Egozi EI, 2003, WOUND REPAIR REGEN, V11, P46, DOI 10.1046/j.1524-475X.2003.11108.x
   Fang KS, 1998, J INVEST DERMATOL, V111, P751, DOI 10.1046/j.1523-1747.1998.00366.x
   Farahani RM, 2008, INT WOUND J, V5, P552, DOI 10.1111/j.1742-481X.2008.00438.x
   FOLKMAN J, 1978, NATURE, V273, P345, DOI 10.1038/273345a0
   Freyman TM, 2001, EXP CELL RES, V269, P140, DOI 10.1006/excr.2001.5302
   Gabbiani G, 2003, J PATHOL, V200, P500, DOI 10.1002/path.1427
   García-Cardeña G, 2001, P NATL ACAD SCI USA, V98, P4478, DOI 10.1073/pnas.071052598
   Gemmiti CV, 2009, BIOTECHNOL BIOENG, V104, P809, DOI 10.1002/bit.22440
   Gilbert TW, 2007, TISSUE ENG, V13, P1313, DOI 10.1089/ten.2006.0318
   GOLD MH, 1993, J DERMATOL SURG ONC, V19, P912, DOI 10.1111/j.1524-4725.1993.tb00978.x
   Gold MH, 2001, DERMATOL SURG, V27, P641, DOI 10.1046/j.1524-4725.2001.00356.x
   Haga JH, 2007, J BIOMECH, V40, P947, DOI 10.1016/j.jbiomech.2006.04.011
   Hinz B, 2001, MOL BIOL CELL, V12, P2730, DOI 10.1091/mbc.12.9.2730
   Hinz B, 2007, J INVEST DERMATOL, V127, P526, DOI 10.1038/sj.jid.5700613
   Holzer P, 1998, GEN PHARMACOL, V30, P5, DOI 10.1016/S0306-3623(97)00078-5
   Hsu M, 2001, PLAST RECONSTR SURG, V107, P1787, DOI 10.1097/00006534-200106000-00023
   Huang S, 1998, MOL BIOL CELL, V9, P3179, DOI 10.1091/mbc.9.11.3179
   Huang S, 2000, EXP CELL RES, V261, P91, DOI 10.1006/excr.2000.5044
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P249, DOI 10.1097/00003086-198901000-00038
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P263
   Jacobs S, 2009, J PLAST RECONSTR AES, V62, P1331, DOI 10.1016/j.bjps.2008.03.024
   Kakisis JD, 2004, ENDOTHELIUM-J ENDOTH, V11, P17, DOI 10.1080/10623320490432452
   Knöll R, 2003, J MOL MED, V81, P750, DOI 10.1007/s00109-003-0488-x
   Lammerding J, 2004, ANN NY ACAD SCI, V1015, P53, DOI 10.1196/annals.1302.005
   LANYON LE, 1984, J BIOMECH, V17, P897, DOI 10.1016/0021-9290(84)90003-4
   LEE RC, 1981, J BIOMECH ENG-T ASME, V103, P280, DOI 10.1115/1.3138294
   LEE RC, 1993, BIOPHYS J, V64, P44, DOI 10.1016/S0006-3495(93)81339-0
   Lehoux S, 2006, J INTERN MED, V259, P381, DOI 10.1111/j.1365-2796.2006.01624.x
   Lehoux S, 2006, CARDIOVASC RES, V71, P269, DOI 10.1016/j.cardiores.2006.05.008
   Li CH, 2007, CELL SIGNAL, V19, P881, DOI 10.1016/j.cellsig.2007.01.004
   Li DQ, 2009, TISSUE ENG PT A, V15, P2773, DOI [10.1089/ten.tea.2008.0540, 10.1089/ten.TEA.2008.0540]
   LONGAKER MT, 1994, ANN SURG, V219, P65, DOI 10.1097/00000658-199401000-00011
   LORENZ HP, 1992, DEVELOPMENT, V114, P253
   LUND T, 1992, WORLD J SURG, V16, P2, DOI 10.1007/BF02067107
   MANDERS EK, 1988, PLAST RECONSTR SURG, V81, P208, DOI 10.1097/00006534-198802000-00012
   Martin P, 2003, CURR BIOL, V13, P1122, DOI 10.1016/S0960-9822(03)00396-8
   McCarty Morgan, 2010, J Clin Aesthet Dermatol, V3, P39
   MCLEOD KJ, 1987, SCIENCE, V236, P1465, DOI 10.1126/science.3589667
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   Morris DE, 1997, PLAST RECONSTR SURG, V100, P674, DOI 10.1097/00006534-199709000-00021
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mustoe TA, 2008, AESTHET PLAST SURG, V32, P82, DOI 10.1007/s00266-007-9030-9
   MYERS MB, 1967, ARCH SURG-CHICAGO, V94, P218
   NAUTA A, 2011, ORAL DIS IN PRESS
   NEUMANN C G, 1957, Plast Reconstr Surg (1946), V19, P124, DOI 10.1097/00006534-195702000-00004
   Nie FQ, 2007, BIOMATERIALS, V28, P4017, DOI 10.1016/j.biomaterials.2007.05.037
   Nishimura K, 2007, WOUND REPAIR REGEN, V15, P646, DOI 10.1111/j.1524-475X.2007.00295.x
   O'Neill AT, 2008, CYTOTECHNOLOGY, V56, P197, DOI 10.1007/s10616-008-9149-9
   Ogawa R, 2003, PLAST RECONSTR SURG, V111, P547, DOI 10.1097/01.PRS.0000040466.55214.35
   Ogawa R, 2008, J BURN CARE RES, V29, P1016, DOI 10.1097/BCR.0b013e31818ba189
   Ogawa R, 2008, MED HYPOTHESES, V71, P493, DOI 10.1016/j.mehy.2008.05.020
   Ogawa R, 2009, STUD MECHANOBIOL TIS, V1, P31
   Ogawa R, 2010, PLAST RECONSTR SURG, V125, P557, DOI 10.1097/PRS.0b013e3181c82dd5
   Orr AW, 2006, DEV CELL, V10, P11, DOI 10.1016/j.devcel.2005.12.006
   Pietramaggiori G, 2007, ANN SURG, V246, P896, DOI 10.1097/SLA.0b013e3180caa47f
   RAAB DM, 1991, J BONE MINER RES, V6, P741
   Reid RR, 2006, WOUND REPAIR REGEN, V14, P138, DOI 10.1111/j.1743-6109.2006.00103.x
   Rhett JM, 2008, TRENDS BIOTECHNOL, V26, P173, DOI 10.1016/j.tibtech.2007.12.007
   Riha GM, 2005, ANN BIOMED ENG, V33, P772, DOI 10.1007/s10439-005-3310-9
   SADOSHIMA J, 1993, CELL, V75, P977, DOI 10.1016/0092-8674(93)90541-W
   Sakuraba M, 2011, SURG TODAY, V41, P496, DOI 10.1007/s00595-010-4265-5
   Sakuraba M, 2010, GEN THORAC CARDIOVAS, V58, P467, DOI 10.1007/s11748-010-0605-z
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Scherer SS, 2009, PLAST RECONSTR SURG, V124, P1458, DOI 10.1097/PRS.0b013e3181bbc829
   Schrementi ME, 2008, WOUND REPAIR REGEN, V16, P80, DOI 10.1111/j.1524-475X.2007.00320.x
   Senba E, 1996, PROG BRAIN RES, V113, P387, DOI 10.1016/S0079-6123(08)61100-0
   Shrader CD, 2008, ARCH DERMATOL RES, V300, P495, DOI 10.1007/s00403-008-0836-3
   Silver FH, 2003, SKIN RES TECHNOL, V9, P3, DOI 10.1034/j.1600-0846.2003.00358.x
   Silverstein P., 1976, ULTRASTRUCTURE COLLA
   SILVERSTEIN P, 1972, ANN RES PROGR REPORT, P30
   Soo C, 2000, PLAST RECONSTR SURG, V105, P638, DOI 10.1097/00006534-200002000-00024
   Stolberg S, 2009, BIOTECHNOL PROGR, V25, P10, DOI 10.1002/btpr.124
   Suetake T, 2000, BRIT J PLAST SURG, V53, P503, DOI 10.1054/bjps.2000.3388
   Szpaderska AM, 2003, J INVEST DERMATOL, V120, P1130, DOI 10.1046/j.1523-1747.2003.12253.x
   TANAKA H, 1995, J HAND SURG-AM, V20A, P467, DOI 10.1016/S0363-5023(05)80109-1
   Ting SB, 2005, SCIENCE, V308, P411, DOI 10.1126/science.1107511
   Turgut G, 2009, J CRANIOFAC SURG, V20, P263, DOI 10.1097/SCS.0b013e3181843766
   WANINGER J, 1992, AM J SURG, V163, P319, DOI 10.1016/0002-9610(92)90013-H
   Wertheimer E, 2000, J INVEST DERMATOL, V115, P24, DOI 10.1046/j.1523-1747.2000.00008.x
   West DC, 1997, INT J BIOCHEM CELL B, V29, P201, DOI 10.1016/S1357-2725(96)00133-1
   Wipff PJ, 2007, J CELL BIOL, V179, P1311, DOI 10.1083/jcb.200704042
   Yeh J, 2009, WOUND REPAIR REGEN, V17, P639, DOI 10.1111/j.1524-475X.2009.00535.x
   Zhang JH, 2003, FASEB J, V17, P926, DOI 10.1096/fj.02-0663fje
   Zhang WB, 2009, METHODS, V47, P122, DOI 10.1016/j.ymeth.2008.09.004
   Zhu KQ, 2005, BURNS, V31, P5, DOI 10.1016/j.burns.2004.08.010
   Zhu KQ, 2004, BURNS, V30, P518, DOI 10.1016/j.burns.2004.02.005
   Zhu KQ, 2003, BURNS, V29, P649, DOI 10.1016/S0305-4179(03)00205-5
   ZHU X, 2003, MED SCI MONITOR, V9, P109
   Zhu YF, 2002, ARCH DERMATOL RES, V293, P560, DOI 10.1007/s00403-001-0277-8
NR 124
TC 136
Z9 170
U1 1
U2 86
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0022-4804
EI 1095-8673
J9 J SURG RES
JI J. Surg. Res.
PD DEC
PY 2011
VL 171
IS 2
BP 700
EP 708
DI 10.1016/j.jss.2011.07.007
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 847FS
UT WOS:000296957900063
PM 22005503
DA 2026-07-24
ER

PT J
AU Molnar, JA
   DeFranzo, AJ
   Hadaegh, A
   Morykwas, MJ
   Shen, P
   Argenta, LC
AF Molnar, JA
   DeFranzo, AJ
   Hadaegh, A
   Morykwas, MJ
   Shen, P
   Argenta, LC
TI Acceleration of integra incorporation in complex tissue defects with
   subatmospheric pressure
SO PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; ARTIFICIAL SKIN; RECONSTRUCTIVE SURGERY;
   CLINICAL-EXPERIENCE; WOUND CONTROL; BURNS; DESIGN; DERMIS; MODEL
AB In an effort to accelerate vascularization and simplify the care of Integra (Ethicon, Inc., Somerville, NJ.), topical subatmospheric pressure was used for eight patients (age range, 2 to 60 years) with complex wounds. Bone was exposed in 62.5 percent of cases, joint in 50 percent, tendon in 37.5 percent, and bowel in 25 percent. The estimated Integra take rate was 96 percent. Split-thickness skin grafting was performed at 4 to 11 days (mean, 7.25 days), with a 93 percent take rate. No adverse side effects were observed with this technique. Application of subatmospheric pressure improved the take rate and time to vascularization of Integra, compared with previous published results, even with complicated wounds. This technique may be a practical alternative to flap closure.
C1 Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27109 USA.
   Wake Forest Univ, Sch Med, Dept Gen Surg, Winston Salem, NC 27109 USA.
C3 Wake Forest University; Wake Forest University
RP Molnar, JA (通讯作者)，Wake Forest Univ, Sch Med, Dept Plast & Reconstruct Surg, Winston Salem, NC 27109 USA.
EM jmolnar@wfubmc.edu
RI Molnar, Joseph/AEK-5540-2022
OI Morykwas, Michael/0009-0001-5547-5172
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BURKE JF, 1981, ANN SURG, V194, P413, DOI 10.1097/00000658-198110000-00005
   Chou TD, 2001, PLAST RECONSTR SURG, V108, P378, DOI 10.1097/00006534-200108000-00015
   Clayton MC, 1998, J BURN CARE REHABIL, V19, P358, DOI 10.1097/00004630-199807000-00017
   Grant I, 2001, BURNS, V27, P699, DOI 10.1016/S0305-4179(01)00040-7
   HEIMBACH D, 1988, ANN SURG, V208, P313, DOI 10.1097/00000658-198809000-00008
   Honari S, 2000, J BURN CARE REHABIL, V21, P190
   Hunt JA, 2000, BRIT J PLAST SURG, V53, P652, DOI 10.1054/bjps.2000.3436
   Machens HG, 2000, CELLS TISSUES ORGANS, V167, P88, DOI 10.1159/000016772
   Moiemen NS, 2001, PLAST RECONSTR SURG, V108, P93, DOI 10.1097/00006534-200107000-00015
   Morykwas MJ, 1999, J BURN CARE REHABIL, V20, P15, DOI 10.1097/00004630-199901001-00003
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Orgill DP, 1999, ANN NY ACAD SCI, V888, P233, DOI 10.1111/j.1749-6632.1999.tb07959.x
   Schneider AM, 1998, PLAST RECONSTR SURG, V102, P1195, DOI 10.1097/00006534-199809040-00045
   SHERIDAN RL, 1994, EUR J PLAST SURG, V17, P91
   Suzuki S, 1999, ANN PLAS SURG, V43, P439, DOI 10.1097/00000637-199910000-00017
   TOMPKINS RG, 1989, CRIT CARE MED, V17, P734, DOI 10.1097/00003246-198908000-00003
   WALTHALL B, 2000, COMMUNICATION
   Wang JCY, 2000, BRIT J PLAST SURG, V53, P70, DOI 10.1054/bjps.1999.3201
   Wu SH, 2000, EUR J PLAST SURG, V23, P174, DOI 10.1007/s002380050243
   YANNAS IV, 1980, J BIOMED MATER RES, V14, P65, DOI 10.1002/jbm.820140108
   YANNAS IV, 1980, J BIOMED MATER RES, V14, P107, DOI 10.1002/jbm.820140203
NR 22
TC 158
Z9 190
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0032-1052
J9 PLAST RECONSTR SURG
JI Plast. Reconstr. Surg.
PD APR 15
PY 2004
VL 113
IS 5
BP 1339
EP 1346
DI 10.1097/01.PRS.0000112746.67050.68
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 809DZ
UT WOS:000220618700004
PM 15060345
DA 2026-07-24
ER

PT J
AU Tessier, JM
   Sanders, J
   Sartelli, M
   Ulrych, J
   De Simone, B
   Grabowski, J
   Buckman, S
   Duane, TM
AF Tessier, Jeffrey M.
   Sanders, James
   Sartelli, Massimo
   Ulrych, Jan
   De Simone, Belinda
   Grabowski, Julia
   Buckman, Sara
   Duane, Therese M.
TI Necrotizing Soft Tissue Infections: A Focused Review of Pathophysiology,
   Diagnosis, Operative Management, Antimicrobial Therapy, and Pediatrics
SO SURGICAL INFECTIONS
LA English
DT Review
DE fasciitis; necrotizing; infection
ID LABORATORY RISK INDICATOR; VACUUM-ASSISTED CLOSURE; A STREPTOCOCCAL
   DISEASE; FASCIITIS LRINEC SCORE; FOURNIERS GANGRENE; COMPLICATED SKIN;
   DELAY PHENOMENON; CHILDREN; MORTALITY; RECONSTRUCTION
AB Background: Necrotizing fasciitis is a major health problem throughout the world. The purpose of this review is to assist providers with the care of these patients through a better understanding of the pathophysiology and management options. Methods: This is a collaborative review of the literature between members of the Surgical Infection Society of North America and World Society of Emergency Surgery. Results: Necrotizing fasciitis continues to be difficult to manage with the mainstay being early diagnosis and surgical intervention. Recognition of at-risk populations assists with the initiation of treatment, thereby impacting outcomes. Conclusions: Although there are some additional treatment strategies available, surgical debridement and antimicrobial therapy are central to the successful eradication of the disease process.
C1 [Tessier, Jeffrey M.] UT Southwestern, Div Infect Dis & Geog Med, Dallas, TX 75390 USA.
   [Sanders, James] UT Southwestern, Antimicrobial Stewardship, Dallas, TX 75390 USA.
   [Sartelli, Massimo] Macerata Hosp, Dept Surg, Macerata, Italy.
   [Ulrych, Jan] Charles Univ Prague, Fac Med 1, Dept Surg 1, Prague, Czech Republic.
   [Ulrych, Jan] Gen Univ Hosp Prague, Prague, Czech Republic.
   [De Simone, Belinda] Parma Univ Hosp, Emergency & Trauma Surg Dept, Parma, Italy.
   [Grabowski, Julia] Northwestern Univ, Dept Pediat Surg, Chicago, IL 60611 USA.
   [Buckman, Sara] Washington Univ, Dept Surg, St Louis, MO 63110 USA.
   [Duane, Therese M.] Envision Healthcare, Dallas, TX USA.
C3 University of Texas System; University of Texas Southwestern Medical
   Center; University of Texas System; University of Texas Southwestern
   Medical Center; Charles University Prague; General University Hospital
   Prague; University of Parma; University Hospital of Parma; Northwestern
   University; Washington University (WUSTL)
RP Sanders, J (通讯作者)，UT Southwestern, 5323 Harry Hines Blvd, Dallas, TX 75390 USA.
EM jsanderspharmdphd@gmail.com
RI Duane, Therese/KCY-3361-2024; De Simone, Belinda/AAD-5646-2019; Ulrych,
   Jan/I-9617-2017; /AAD-7440-2020
OI Ulrych, Jan/0000-0002-5225-9562; 
CR Agarwal R, 2018, CLIN MICROBIOL INFEC, V24, P361, DOI 10.1016/j.cmi.2017.08.028
   Amini R, 2014, ACAD EMERG MED, V21, P799, DOI 10.1111/acem.12408
   Anaya DA, 2005, ARCH SURG-CHICAGO, V140, P151, DOI 10.1001/archsurg.140.2.151
   Anaya DA, 2007, CLIN INFECT DIS, V44, P705, DOI 10.1086/511638
   [Anonymous], 2014, CURR PROB SURG, V51, P344, DOI 10.1067/j.cpsurg.2014.06.001
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Aronoff DM, 2013, ANAEROBE, V24, P98, DOI 10.1016/j.anaerobe.2013.08.009
   BASKIN LS, 1990, BRIT J UROL, V65, P524, DOI 10.1111/j.1464-410X.1990.tb14801.x
   Bechar J, 2017, ANN ROY COLL SURG, V99, P341, DOI 10.1308/rcsann.2017.0053
   Bilton BD, 1998, AM SURGEON, V64, P397
   Bingöl-Kologlu M, 2007, J PEDIATR SURG, V42, P1892, DOI 10.1016/j.jpedsurg.2007.07.018
   Bronder C S, 2004, Colorectal Dis, V6, P518, DOI 10.1111/j.1463-1318.2004.00663.x
   Bryant AE, 2006, J MED MICROBIOL, V55, P495, DOI 10.1099/jmm.0.46390-0
   Burner E, 2016, WEST J EMERG MED, V17, P333, DOI 10.5811/westjem.2016.2.29069
   CALLEGARI PR, 1992, PLAST RECONSTR SURG, V89, P397, DOI 10.1097/00006534-199203000-00001
   Carbonetti F, 2016, RADIOL MED, V121, P106, DOI 10.1007/s11547-015-0575-4
   Carratalà J, 2003, EUR J CLIN MICROBIOL, V22, P151, DOI 10.1007/s10096-003-0902-x
   Chaudhry AA, 2015, AM J ROENTGENOL, V204, P128, DOI 10.2214/AJR.14.12676
   Chen SY, 2011, J PLAST RECONSTR AES, V64, P528, DOI 10.1016/j.bjps.2010.07.018
   Cheng NC, 2011, ANN PLAS SURG, V67, P632, DOI 10.1097/SAP.0b013e31820b372b
   Cho JC, 2018, PHARMACOTHERAPY, V38, P108, DOI 10.1002/phar.2050
   Clark P, 2003, CAN J SURG, V46, P9
   Cocanour CS, 2017, SURG INFECT, V18, P250, DOI 10.1089/sur.2016.200
   Colak E, 2014, TURK J EMERG MED, V14, P15, DOI 10.5505/1304.7361.2014.55476
   Cunningham MW, 2008, ADV EXP MED BIOL, V609, P29, DOI 10.1007/978-0-387-73960-1_3
   Dahesh S, 2008, ANTIMICROB AGENTS CH, V52, P2915, DOI 10.1128/AAC.00461-08
   Dhar SC, 1999, PLAST RECONSTR SURG, V104, P2079, DOI 10.1097/00006534-199912000-00021
   DIFALCO G, 1986, DIS COLON RECTUM, V29, P582, DOI 10.1007/BF02554263
   Dijkstra Angelique, 2009, Ned Tijdschr Geneeskd, V153, P408
   Dryden M, 2016, J ANTIMICROB CHEMOTH, V71, P3575, DOI 10.1093/jac/dkw333
   Ekingen G, 2008, J PEDIATR SURG, V43, pE39, DOI 10.1016/j.jpedsurg.2008.09.014
   El-Khatib H A, 2007, Ann Burns Fire Disasters, V20, P78
   El-Menyar A, 2017, SCAND J TRAUMA RESUS, V25, DOI 10.1186/s13049-017-0359-z
   Elliott D, 2000, AM J SURG, V179, P361, DOI 10.1016/S0002-9610(00)00360-3
   Elliott DC, 1996, ANN SURG, V224, P672, DOI 10.1097/00000658-199611000-00011
   Endorf FW, 2012, PEDIATR INFECT DIS J, V31, P221, DOI 10.1097/INF.0b013e3182456f02
   Eneli I, 2007, J PEDIATR-US, V151, P79, DOI 10.1016/j.jpeds.2007.02.019
   ENRIQUEZ JM, 1987, DIS COLON RECTUM, V30, P33, DOI 10.1007/BF02556919
   Ferreira PC, 2007, PLAST RECONSTR SURG, V119, P175, DOI 10.1097/01.prs.0000244925.80290.57
   Fitzmaurice M, 2006, J PLAST RECONSTR AES, V59, P1249, DOI 10.1016/j.bjps.2006.02.009
   Flores-Díaz M, 2016, MICROBIOL MOL BIOL R, V80, P597, DOI 10.1128/MMBR.00082-15
   Fustes-Morales A, 2002, ARCH DERMATOL, V138, P893, DOI 10.1001/archderm.138.7.893
   Gausepohl JS, 2015, WEST J EMERG MED, V16, P172, DOI 10.5811/westjem.2014.12.21553
   GERBER GS, 1994, UROLOGY, V44, P779, DOI 10.1016/S0090-4295(94)80230-0
   GOLD WL, 1993, CLIN INFECT DIS, V16, P69, DOI 10.1093/clinids/16.1.69
   Hansen MB, 2017, SCI REP-UK, V7, DOI 10.1038/srep42179
   Harbrecht BG, 2016, SURG INFECT, V17, P503, DOI 10.1089/sur.2016.049
   Harris PNA, 2018, JAMA-J AM MED ASSOC, V320, P984, DOI 10.1001/jama.2018.12163
   Hietbrink F, 2016, WORLD J EMERG SURG, V11, DOI 10.1186/s13017-016-0108-z
   Hodgins N, 2015, J PLAST RECONSTR AES, V68, P304, DOI 10.1016/j.bjps.2014.11.003
   Holland MJ, 2009, ANAESTH INTENS CARE, V37, P588, DOI 10.1177/0310057X0903700416
   Howell GM, 2011, SURG INFECT, V12, P185, DOI 10.1089/sur.2011.032
   Hsieh T, 2000, CAN MED ASSOC J, V163, P393
   Hsieh WS, 1999, PEDIATRICS, V103, DOI 10.1542/peds.103.4.e53
   Huang WS, 2006, ASIAN J SURG, V29, P133
   Jamal N, 2011, PEDIATR EMERG CARE, V27, P1195, DOI 10.1097/PEC.0b013e31823b583c
   Janda JM, 2010, CLIN MICROBIOL REV, V23, P35, DOI 10.1128/CMR.00039-09
   Kennedy CL, 2009, INFECT IMMUN, V77, P943, DOI 10.1128/IAI.01267-08
   Kiat Ho Jun, 2017, J Emerg Trauma Shock, V10, P205, DOI [10.4103/jets.jets_42_17, 10.4103/JETS.JETS_42_17]
   Kihiczak GG, 2006, J EUR ACAD DERMATOL, V20, P365, DOI 10.1111/J.1468-3083.2006.01487.x
   Kim KT, 2011, RADIOLOGY, V259, P816, DOI 10.1148/radiol.11101164
   Kisgen JJ, 2014, AM J HEALTH-SYST PH, V71, P621, DOI 10.2146/ajhp130482
   Kobayashi L, 2011, J TRAUMA, V71, P1400, DOI 10.1097/TA.0b013e31820db8fd
   Kosmidis C, 2010, EXPERT OPIN PHARMACO, V11, P615, DOI 10.1517/14656561003598893
   Kulkarni Madhuri, 2014, J Lab Physicians, V6, P46, DOI 10.4103/0974-2727.129092
   LAUCKS SS, 1994, SURG CLIN N AM, V74, P1339
   Laupland KB, 2000, PEDIATRICS, V105, DOI 10.1542/peds.105.5.e60
   Lee TC, 2007, AM J SURG, V194, P809, DOI 10.1016/j.amjsurg.2007.08.047
   Legbo JN, 2005, ANN TROP PAEDIATR, V25, P183, DOI 10.1179/146532805X58111
   Levin L S, 2001, Foot Ankle Clin, V6, P853, DOI 10.1016/S1083-7515(02)00015-3
   Lille ST, 1996, J AM COLL SURGEONS, V182, P7
   Lonergan S, 2004, J EMERG MED, V26, P47, DOI 10.1016/j.jemermed.2003.06.003
   Mallikarjuna M N, 2012, ISRN Surg, V2012, P942437, DOI 10.5402/2012/942437
   Marinis Athanasios, 2013, Infez Med, V21, P305
   May AK, 2009, SURG INFECT, V10, P467, DOI 10.1089/sur.2009.012
   MCDOUGAL WS, 1983, J UROLOGY, V129, P757, DOI 10.1016/S0022-5347(17)52343-5
   MCHENRY CR, 1995, ANN SURG, V221, P558, DOI 10.1097/00000658-199505000-00013
   Miranda D, 2018, SURG INFECT, V19, P745, DOI 10.1089/sur.2018.225
   Misiakos EP, 2014, FRONT SURG, V1, DOI 10.3389/fsurg.2014.00036
   Mohty KM, 2017, CUREUS J MED SCIENCE, V9, DOI 10.7759/cureus.1168
   Moiemen NS, 2001, PLAST RECONSTR SURG, V108, P93, DOI 10.1097/00006534-200107000-00015
   Mongelluzzo J, 2017, WEST J EMERG MED, V18, P398, DOI 10.5811/westjem.2016.12.32838
   Morpurgo E, 2002, SURG CLIN N AM, V82, P1213, DOI 10.1016/S0039-6109(02)00058-0
   MORRIS SF, 1995, PLAST RECONSTR SURG, V95, P526, DOI 10.1097/00006534-199503000-00014
   Moss RLM, 1996, J PEDIATR SURG, V31, P1142, DOI 10.1016/S0022-3468(96)90104-9
   Narasimhan V, 2018, ANZ J SURG, V88, pE45, DOI 10.1111/ans.13895
   Navarro MA, 2018, TOXINS, V10
   Neeki MM, 2017, WEST J EMERG MED, V18, P684, DOI 10.5811/westjem.2017.3.33607
   NICKEL JC, 1983, CAN MED ASSOC J, V129, P445
   Nisbet M, 2011, INTERN MED J, V41, P543, DOI 10.1111/j.1445-5994.2009.02137.x
   Okoye O, 2013, AM SURGEON, V79, P1081
   Ozturk E, 2009, AM J SURG, V197, P660, DOI 10.1016/j.amjsurg.2008.04.018
   Park SY, 2019, DIAGN MICR INFEC DIS, V94, P183, DOI 10.1016/j.diagmicrobio.2018.12.013
   Payinda G, 2008, NEW ZEAL MED J, V121, P99
   Popoff MR, 2014, ANAEROBE, V30, P220, DOI 10.1016/j.anaerobe.2014.05.014
   Puvanendran R, 2009, CAN FAM PHYSICIAN, V55, P981
   Rahim GR, 2019, CLIN MICROBIOL INFEC, V25, P316, DOI 10.1016/j.cmi.2018.05.008
   Rindone JP, 2018, BRIT J CLIN PHARMACO, V84, P1258, DOI 10.1111/bcp.13554
   Sabbaj A, 2009, ACAD EMERG MED, V16, P1290, DOI 10.1111/j.1553-2712.2009.00536.x
   Sartelli M, 2018, WORLD J EMERG SURG, V13, DOI 10.1186/s13017-018-0219-9
   Sartelli M, 2014, WORLD J EMERG SURG, V9, DOI 10.1186/1749-7922-9-57
   SAYMEN DG, 1973, APPL MICROBIOL, V25, P921, DOI 10.1128/AEM.25.6.921-934.1973
   Schweizer ML, 2011, BMC INFECT DIS, V11, DOI 10.1186/1471-2334-11-279
   Silberstein Jonathan, 2008, Rev Urol, V10, P76
   Smith GL, 1998, BRIT J UROL, V81, P347
   Stevens DL, 2014, CLIN INFECT DIS, V59, pE10, DOI [10.1093/cid/ciu296, 10.1093/cid/ciu444]
   Stevens DL, 2012, ANAEROBE, V18, P254, DOI 10.1016/j.anaerobe.2011.11.001
   STEVENS DL, 1995, EMERG INFECT DIS, V1, P69, DOI 10.3201/eid0103.950301
   Swain RA, 2013, ANN ROY COLL SURG, V95, P57, DOI 10.1308/003588413X13511609956093
   Tang WM, 2001, J BONE JOINT SURG BR, V83B, P709, DOI 10.1302/0301-620X.83B5.10987
   Thom C, 2017, J EMERG MED, V52, P523, DOI 10.1016/j.jemermed.2016.09.007
   TIWARI IN, 1980, PLAST RECONSTR SURG, V66, P605, DOI 10.1097/00006534-198010000-00019
   Tom LK, 2016, J AM COLL SURGEONS, V222, pE47, DOI 10.1016/j.jamcollsurg.2016.01.008
   Tong SYC, 2015, CLIN MICROBIOL REV, V28, P603, DOI 10.1128/CMR.00134-14
   Tsitsilonis S, 2013, LANGENBECK ARCH SURG, V398, P153, DOI 10.1007/s00423-012-0983-z
   Tyrrell GJ, 2005, CLIN INFECT DIS, V40, P1055, DOI 10.1086/428614
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Vick R, 1999, UROL CLIN N AM, V26, P841, DOI 10.1016/S0094-0143(05)70224-X
   VOROS D, 1993, BRIT J SURG, V80, P1190, DOI 10.1002/bjs.1800800943
   Vural C, 2003, AM J OTOLARYNG, V24, P143, DOI 10.1016/S0196-0709(03)00008-5
   Wakhlu A, 2006, J PEDIATR SURG, V41, P1144, DOI 10.1016/j.jpedsurg.2006.02.013
   Waldhausen JHT, 1996, J PEDIATR SURG, V31, P1138, DOI 10.1016/S0022-3468(96)90103-7
   Weigelt J, 2005, ANTIMICROB AGENTS CH, V49, P2260, DOI 10.1128/AAC.49.6.2260-2266.2005
   Wilson MP, 2013, J EMERG MED, V44, P928, DOI 10.1016/j.jemermed.2012.09.039
   WOLACH MD, 1989, BRIT J UROL, V64, P310, DOI 10.1111/j.1464-410X.1989.tb06020.x
   Wong CH, 2003, J BONE JOINT SURG AM, V85A, P1454, DOI 10.2106/00004623-200308000-00005
   Yen ZS, 2002, ACAD EMERG MED, V9, P1448, DOI 10.1111/j.1553-2712.2002.tb01619.x
   Zenn MR, 2004, SEMIN COLON RECTAL S, V15, P59
   Zundel S, 2017, EUR J PEDIATR SURG, V27, P127, DOI 10.1055/s-0036-1584531
NR 129
TC 22
Z9 29
U1 0
U2 14
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD MAR 1
PY 2020
VL 21
IS 2
BP 81
EP 93
DI 10.1089/sur.2019.219
EA OCT 2019
PG 13
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA KM6VR
UT WOS:000489026800001
PM 31584343
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Assenza, M
   Valesini, L
   Monacelli, G
   Simonelli, L
   Antoniozzi, A
   Ferrazza, GC
   Usai, V
   Romeo, V
   Modini, C
AF Assenza, M.
   Valesini, L.
   Monacelli, G.
   Simonelli, L.
   Antoniozzi, A.
   Ferrazza, G. C.
   Usai, V.
   Romeo, V.
   Modini, C.
TI Traumatic complex wounds, multidisciplinary approach: our experience in
   a case series
SO CLINICA TERAPEUTICA
LA English
DT Article
DE damage control; PRP gel; traumatic complex wound; VAC therapy
AB "Limb-salvage" is a social problem that is rapidly increasing, both in Italy and in the rest of world. Today, as in earlier times, the main causes of open wounds are traumas and such injuries are mainly of II and III stage of Gustilo's classification. Nowadays, the use of modern techniques determined a further dramatic reduction in the infection rates and, above all, in the risk of limb amputation. The most important techniques include: V. A. C. therapy (vacuum assisted closure); PRP gel (platelet-rich plasma gel); hyperbaric oxygen therapy. We treated 4 patients with high energy acute trauma through the combined and innovative use of advanced dressings. The authors report their experience and a brief review of the literature as contribution in regards to treatment of complex wounds of the limbs.
C1 [Assenza, M.; Valesini, L.; Monacelli, G.; Simonelli, L.; Antoniozzi, A.; Usai, V.; Romeo, V.; Modini, C.] Sapienza Univ Roma, Dipartiment Chirurg Urgenza & Trauma, Rome, Italy.
   [Ferrazza, G. C.] Sapienza Univ Roma, Dipartiment Ematol Oncol Immunoematol & Med Rigen, Rome, Italy.
C3 Sapienza University Rome; Sapienza University Rome
RP Assenza, M (通讯作者)，Sapienza Univ Roma, Policlin Umberto I, Dipartimento Chirurg Urgenza & Trauma, Rome, Italy.
EM marco.assenza@uniroma1.it
RI ; ASSENZA, Marco/LLK-2745-2024
OI ferrazza, giancarlo/0000-0003-3483-900X; ASSENZA,
   Marco/0000-0002-0400-5410
CR DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Kairinos N, 2009, PLAST RECONSTR SURG, V123, P589, DOI 10.1097/PRS.0b013e3181956551
   Kazakos K, 2009, INJURY, V40, P801, DOI 10.1016/j.injury.2008.05.002
   LALLISS SJ, 2007, ANN M ORTH TRAUM ASS
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Morykwas MJ, 2001, ANN PLAS SURG, V47, P547, DOI 10.1097/00000637-200111000-00013
   Pape HC, 2008, J ORTHOP TRAUMA, V22, pS133, DOI 10.1097/BOT.0b013e318188e26b
   Pollak AN, 2008, J ORTHOP TRAUMA, V22, pS142, DOI 10.1097/BOT.0b013e318188e2a9
   Rozman P, 2007, ACTA DERMATOVEN ALP, V16, P156
   Saxena V, 2004, PLAST RECONSTR SURG, V114, P1086, DOI 10.1097/01.prs.0000135330.51408.97
NR 11
TC 2
Z9 2
U1 0
U2 1
PU SOC EDITRICE UNIV
PI ROME
PA VIA G B MORGAGNI 1, ROME, 10061, ITALY
SN 0009-9074
EI 1972-6007
J9 CLIN TER
JI Clin. Ter.
PD MAY-JUN
PY 2010
VL 161
IS 3
SU S
BP E95
EP E99
PG 5
WC Medicine, General & Internal; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Pharmacology & Pharmacy
GA V28ZK
UT WOS:000208718500003
PM 20589349
DA 2026-07-24
ER

PT J
AU van Wessem, KJP
AF van Wessem, K. J. P.
TI Possible Devices to Temporary Cover the Open Abdomen : Pros and Cons
SO ACTA CHIRURGICA BELGICA
LA English
DT Review
DE Temporary abdominal closure; open abdomen; damage control surgery
ID OPEN ABDOMINAL WOUNDS; VACUUM-ASSISTED CLOSURE; FASCIAL CLOSURE;
   DAMAGE-CONTROL; PACK TECHNIQUE; TRAUMA; EXPERIENCE; MANAGEMENT; MESH
AB In the last 25 years increased popularity of damage control surgery and recognition of abdominal compartment syndrome has lead to a raised incidence of open abdomens. Even though these procedures are often life-saving, morbidity and mortality associated with an open abdomen remains high. Third spacing after aggressive fluid resuscitation, fascial retraction, ventilatory problems and fistula formations are problems often associated with an open abdomen. Management of an open abdomen is often complicated and challenging. The viscera need to be protected and the abdomen needs coverage. Several techniques have been described for both temporary and definitive closure. This article will discuss the pros and cons of several available temporary devices to cover the abdomen and literature will be reviewed.
C1 Univ Med Ctr Utrecht, Dept Trauma Surg, NL-3584 CX Utrecht, Netherlands.
C3 Utrecht University; Utrecht University Medical Center
RP van Wessem, KJP (通讯作者)，Univ Med Ctr Utrecht, Dept Trauma Surg, Heidelberglaan 100, NL-3584 CX Utrecht, Netherlands.
EM K.J.P.Wessem@umcutrecht.nl
CR APRAHAMIAN C, 1990, J TRAUMA, V30, P719, DOI 10.1097/00005373-199006000-00011
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Barker DE, 2007, J AM COLL SURGEONS, V204, P784, DOI 10.1016/j.jamcollsurg.2006.12.039
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   BROCK WB, 1995, AM SURGEON, V61, P30
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   DAYTON MT, 1986, ARCH SURG-CHICAGO, V121, P654
   Diaz JJ, 2010, J TRAUMA, V68, P1425, DOI 10.1097/TA.0b013e3181da0da5
   Fernandez L, 1996, J TRAUMA, V40, P258, DOI 10.1097/00005373-199602000-00014
   Mayberry JC, 2004, J TRAUMA, V57, P157, DOI 10.1097/01.TA.0000102411.69521.80
   Miller RS, 2005, J TRAUMA, V59, P1365, DOI 10.1097/01.ta.0000196004.49422.af
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   PHILIPS B, 2008, LEVELS SCI
   Rao M, 2007, COLORECTAL DIS, V9, P266, DOI 10.1111/j.1463-1318.2006.01154.x
   Reilly P, 2003, J TRAUMA, V54, P859
   Reimer MW, 2008, CAN J SURG, V51, P209
   ROTONDO MF, 1993, J TRAUMA, V35, P375, DOI 10.1097/00005373-199309000-00008
   Rutherford E. J., 2004, CURR PROB SURG, V41, P821
   SCHECTER WP, 1936, J AM COLL SURGEONS, V203, P390
   Schwartz A, 1997, INT SURG, V82, P42
   Smith LA, 1997, AM SURGEON, V63, P1102
   Stone PA, 2004, J TRAUMA, V57, P1082, DOI 10.1097/01.TA.0000149248.02598.9E
   Subramonia S, 2009, WORLD J SURG, V33, P931, DOI 10.1007/s00268-009-9947-z
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   Vargo D, 2009, AM SURGEON, V75, pS1
   WALSH GL, 1988, SURG CLIN N AM, V68, P25
NR 26
TC 3
Z9 3
U1 0
U2 4
PU ACTA MEDICAL BELGICA
PI BRUSSELS
PA AVENUE CIRCULAIRE 138 A, B-1180 BRUSSELS, BELGIUM
SN 0001-5458
J9 ACTA CHIR BELG
JI Acta Chir. Belg.
PD SEP-OCT
PY 2010
VL 110
IS 5
BP 499
EP 503
DI 10.1080/00015458.2010.11680664
PG 5
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 684PI
UT WOS:000284561400001
PM 21158323
DA 2026-07-24
ER

PT J
AU Cainzos, M
   Gonzalez-Rodriguez, FJ
AF Cainzos, Miguel
   Gonzalez-Rodriguez, Francisco J.
TI Necrotizing soft tissue infections
SO CURRENT OPINION IN CRITICAL CARE
LA English
DT Review
DE group A beta-nemolytic streptocci; myonecrosis; necrotizing fasciitis;
   necrotizing soft tissue infection
ID VACUUM-ASSISTED CLOSURE; GROUP-A STREPTOCOCCI; FASCIITIS; MANAGEMENT;
   CHILDREN; THERAPY; HEAD; NECK; SKIN
AB Purpose of review The purpose of this review is to consider recent advances in the definition, pathogenesis, diagnostic criteria, and treatment of necrotizing soft tissue infections.
   Recent findings The efficacy of early surgical debridement combined with antimicrobial therapy, close monitoring and physiologic support is strongly demonstrated. Novel therapeutic strategies including vacuum-assisted wound-closure therapy and intravenous immunoglobulin have been described.
   Summary Necrotizing soft-tissue infection is a rare infection of the subcutaneous tissue and fascia that is often associated with sepsis and can progress rapidly with a possible fatal outcome. Although the cause is not yet understood fully, patients often have a prior history of a small, trivial trauma, wound, or scratch. Establishing the diagnosis can be the main challenge in treating patients, and knowledge of all available tools is key for early and accurate diagnosis.
C1 Hosp Clin Univ, Sch Med, Dept Surg, Santiago De Compostela 15706, Spain.
C3 Complexo Hospitalario Universitario de Santiago de Compostela
RP Cainzos, M (通讯作者)，Hosp Clin Univ, Sch Med, Dept Surg, C Vidan S-N, Santiago De Compostela 15706, Spain.
EM ci28@usc.es
CR Ali MH, 1997, ANN SAUDI MED, V17, P641, DOI 10.5144/0256-4947.1997.641
   Anaya DA, 2005, ARCH SURG-CHICAGO, V140, P151, DOI 10.1001/archsurg.140.2.151
   Anaya DA, 2007, CLIN INFECT DIS, V44, P705, DOI 10.1086/511638
   Andrews BT, 2006, HEAD NECK-J SCI SPEC, V28, P974, DOI 10.1002/hed.20496
   Bryant AE, 2005, J INFECT DIS, V192, P1014, DOI 10.1086/432729
   Buettner MF, 2007, EMERG MED CLIN N AM, V25, P177, DOI 10.1016/j.emc.2007.01.008
   Butterworth SA, 2006, J PEDIATR SURG, V41, P935, DOI 10.1016/j.jpedsurg.2006.01.012
   Crum-Cianflone NF, 2006, BEST PRACT RES CL RH, V20, P1083, DOI 10.1016/j.berh.2006.08.005
   Eran Y, 2007, MOL MICROBIOL, V63, P1209, DOI 10.1111/j.1365-2958.2007.05581.x
   Fitzmaurice M, 2006, J PLAST RECONSTR AES, V59, P1249, DOI 10.1016/j.bjps.2006.02.009
   Gegundez Gomez Carlos, 2007, Cir Esp, V81, P99
   Hefny AF, 2007, EUR J EMERG MED, V14, P50, DOI 10.1097/01.mej.0000228447.48276.7b
   Kao Lillian S, 2005, Surg Infect (Larchmt), V6, P427, DOI 10.1089/sur.2005.6.427
   Kaul R, 1999, CLIN INFECT DIS, V28, P800, DOI 10.1086/515199
   Kihiczak GG, 2006, J EUR ACAD DERMATOL, V20, P365, DOI 10.1111/J.1468-3083.2006.01487.x
   KRENK L, 2007, EUR ARCH OTORHI 0306
   Ku HW, 2006, J EMERG MED, V30, P95, DOI 10.1016/j.jemermed.2005.03.014
   Lee CC, 2006, J CLIN MICROBIOL, V44, P1181, DOI 10.1128/JCM.44.3.1181-1183.2006
   Liu SYW, 2006, WORLD J GASTROENTERO, V12, P5256
   Lopez FA, 2006, INFECT DIS CLIN N AM, V20, P759, DOI 10.1016/j.idc.2006.09.006
   Louis ML, 2006, REV CHIR ORTHOP, V92, P504, DOI 10.1016/S0035-1040(06)75839-1
   Malani AK, 2006, LANCET, V368, P1573, DOI 10.1016/S0140-6736(06)69658-X
   MARRON CD, 2006, BMC SURG, V29, P6
   Morgan WR, 2007, J CLIN MICROBIOL, V45, P668, DOI 10.1128/JCM.01657-06
   Nyako Ea, 2006, Ghana Med J, V40, P65
   Ogilvie CM, 2006, CLIN ORTHOP RELAT R, P179, DOI 10.1097/01.blo.0000218734.46376.89
   Piedra T, 2007, EMERG RADIOL, V13, P345, DOI 10.1007/s10140-006-0566-9
   Prokuski Laura, 2006, J Am Acad Orthop Surg, V14, pS101
   Reid SD, 2006, FEMS IMMUNOL MED MIC, V48, P283, DOI 10.1111/j.1574-695X.2006.00150.x
   Safioleas M, 2006, INT UROL NEPHROL, V38, P653, DOI 10.1007/s11255-005-2946-6
   Simonen SME, 2006, EPIDEMIOL INFECT, V134, P293, DOI 10.1017/S095026880500484X
   Smeets L, 2006, Rev Med Liege, V61, P240
   Smith GH, 2007, EMERG MED J, V24, DOI 10.1136/emj.2006.041723
   Spock CR, 2006, SPINE, V31, pE342, DOI 10.1097/01.brs.0000217631.73632.37
   Stollery Nigel, 2006, Practitioner, V250, P54
   Tanna A, 2006, J MED MICROBIOL, V55, P1419, DOI 10.1099/jmm.0.46465-0
   Thulin P, 2006, PLOS MED, V3, P371, DOI 10.1371/journal.pmed.0030053
   Tsai YH, 2007, J BONE JOINT SURG AM, V89A, P631, DOI 10.2106/JBJS.F.00580
   Valiquette L, 2006, SCAND J INFECT DIS, V38, P977, DOI 10.1080/00365540600786499
   Vayalumkal Joseph V, 2006, Paediatr Drugs, V8, P99, DOI 10.2165/00148581-200608020-00003
   Vinh Donald C, 2006, Curr Infect Dis Rep, V8, P375, DOI 10.1007/s11908-006-0048-y
   Wartha F, 2007, CURR OPIN MICROBIOL, V10, P52, DOI 10.1016/j.mib.2006.12.005
   Weiland DE, 2007, AM SURGEON, V73, P261
   Zuloaga-Salcedo Soraya, 2005, Int Wound J, V2, P178, DOI 10.1111/j.1742-4801.2005.00104.x
   [No title captured]
NR 45
TC 78
Z9 91
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1070-5295
EI 1531-7072
J9 CURR OPIN CRIT CARE
JI Curr. Opin. Crit. Care
PD AUG
PY 2007
VL 13
IS 4
BP 433
EP 439
DI 10.1097/MCC.0b013e32825a6a1b
PG 7
WC Critical Care Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 191EA
UT WOS:000248111700012
PM 17599015
DA 2026-07-24
ER

PT J
AU Yuan, YJ
   Ren, JN
   He, YL
AF Yuan, Yujie
   Ren, Jianan
   He, Yulong
TI Current Status of the Open Abdomen Treatment for Intra-Abdominal
   Infection
SO GASTROENTEROLOGY RESEARCH AND PRACTICE
LA English
DT Review
ID TOPICAL NEGATIVE-PRESSURE; TEMPORARY ABDOMINAL CLOSURE; VACUUM-ASSISTED
   CLOSURE; PRIMARY FASCIAL CLOSURE; ENTERAL NUTRITION; SEPTIC PATIENTS;
   DAMAGE CONTROL; MANAGEMENT; TRAUMA; PERITONITIS
AB The open abdomen has become an important approach for critically ill patients who require emergent abdominal surgical interventions. This treatment, originating from the concept of damage control surgery, was first applied in severe traumatic patients. The ultimate goal is to achieve formal abdominal fascial closure by several attempts and adjuvant therapies (fluid management, nutritional support, skin grafting, etc.). Up to the present, open abdomen therapy becomes matured and is multistage-approached in the management of patients with severe trauma. However, its application in patients with intra-abdominal infection still presents great challenges due to critical complications and poor clinical outcomes. This review focuses on the specific use of the open abdomen in such populations and detailedly introduces current concerns and advanced progress about this therapy.
C1 [Yuan, Yujie; He, Yulong] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Gastrointestinal & Pancreat Surg, Guangzhou 510080, Guangdong, Peoples R China.
   [Ren, Jianan] Nanjing Univ, Sch Med, Jinling Hosp, Dept Surg, Nanjing 210002, Jiangsu, Peoples R China.
C3 Sun Yat Sen University; Nanjing University
RP Ren, JN (通讯作者)，Nanjing Univ, Sch Med, Jinling Hosp, Dept Surg, 305 East Zhongshan Rd, Nanjing 210002, Jiangsu, Peoples R China.
EM jiananr@gmail.com
RI ; Yuan, Yujie/O-9873-2018
OI Ren, Jianan/0000-0002-7978-8093; Yuan, Yujie/0000-0001-5786-4377
FU Climbing Program in the Natural Science Foundation of Jiangsu Province
   for Distinguished Scholars [BK2010017]; High-Level Personnel Training
   Project, Jiangsu, China [BRA2011232]
FX This study was supported by Grants from the Climbing Program in the
   Natural Science Foundation of Jiangsu Province for Distinguished
   Scholars (no. BK2010017) and the High-Level Personnel Training Project,
   Jiangsu, China (BRA2011232).
CR Acosta S, 2011, BRIT J SURG, V98, P735, DOI 10.1002/bjs.7383
   Aksoy M., 2012, USE DYNAMIC WOUND CL
   Amin AI, 2009, WORLD J GASTROENTERO, V15, P3394, DOI 10.3748/wjg.15.3394
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Bjorck M, 2012, Br J Surg, V99, P1732, DOI 10.1002/bjs.8917
   Björck M, 2009, WORLD J SURG, V33, P1154, DOI 10.1007/s00268-009-9996-3
   BRADLEY SJ, 1985, ARCH SURG-CHICAGO, V120, P629
   Burlew CC, 2012, J TRAUMA ACUTE CARE, V73, P1380, DOI 10.1097/TA.0b013e318259924c
   Carlson GL, 2013, ANN SURG, V257, P1154, DOI 10.1097/SLA.0b013e31828b8bc8
   Caro A, 2011, INT WOUND J, V8, P274, DOI 10.1111/j.1742-481X.2011.00782.x
   Cheatham ML, 2007, CRIT CARE MED, V35, P127, DOI 10.1097/01.CCM.0000250390.49380.94
   D'Hondt M, 2011, AM J SURG, V202, pE20, DOI 10.1016/j.amjsurg.2010.06.025
   de Costa A, 2006, ANZ J SURG, V76, P356, DOI 10.1111/j.1445-2197.2006.03638.x
   De Laet IE, 2008, LANGENBECK ARCH SURG, V393, P833, DOI 10.1007/s00423-008-0347-x
   Demetriades D, 2012, INT WOUND J, V9, P17, DOI 10.1111/j.1742-481X.2012.01018.x
   diZerega GS, 1997, EUR J SURG, V163, P10
   DUFF JH, 1981, SURGERY, V90, P774
   GARCIASABRIDO JL, 1988, ARCH SURG-CHICAGO, V123, P152
   Goussous N, 2012, SURGERY, V152, P777, DOI 10.1016/j.surg.2012.07.015
   Horwood J, 2009, ANN ROY COLL SURG, V91, P681, DOI 10.1308/003588409X12486167520993
   Ivatury RR, 2007, ACTA CLIN BELG, V62, P206, DOI 10.1179/acb.2007.62.s1.027
   Ivatury R, 2009, WORLD J SURG, V33, P1150, DOI 10.1007/s00268-009-0005-7
   López-Quintero L, 2010, CIR CIR, V78, P317
   MORRIS JA, 1993, ANN SURG, V217, P576, DOI 10.1097/00000658-199305010-00019
   Nicholas JM, 2003, J TRAUMA, V55, P1095, DOI 10.1097/01.TA.0000101067.52018.42
   Padalino P, 2010, SURG INFECT, V11, P523, DOI 10.1089/sur.2010.042
   Pliakos I, 2012, AM SURGEON, V78, P957
   Pliakos I, 2010, SURGERY, V148, P947, DOI 10.1016/j.surg.2010.01.021
   Powell NJ, 2012, NUTR CLIN PRACT, V27, P499, DOI 10.1177/0884533612450918
   PUJOL JP, 1975, THESIS UERX BICHAT P
   Quyn AJ, 2012, COLORECTAL DIS, V14, pE429, DOI 10.1111/j.1463-1318.2012.03045.x
   Regner JL, 2012, WORLD J SURG, V36, P497, DOI 10.1007/s00268-011-1203-7
   Riha GM, 2013, JAMA SURG, V148, P59, DOI 10.1001/2013.jamasurg.4
   ROTONDO MF, 1993, J TRAUMA, V35, P375, DOI 10.1097/00005373-199309000-00008
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   Schecter WP, 2011, SURG CLIN N AM, V91, P481, DOI 10.1016/j.suc.2011.02.004
   Schietroma M, 2012, AM SURGEON, V78, P582
   Schmelzle M, 2010, DIGEST SURG, V27, P272, DOI 10.1159/000314609
   Scholtes M, 2012, WORLD J SURG, V36, P1557, DOI 10.1007/s00268-012-1534-z
   Shah SK, 2012, SCAND J TRAUMA RESUS, V20, DOI 10.1186/1757-7241-20-25
   Shapiro MB, 2000, J TRAUMA, V49, P969, DOI 10.1097/00005373-200011000-00033
   Spain D. A., 2013, ICU DIRECTOR, V4
   Takizawa Y, 2011, EUR J PHARM SCI, V42, P246, DOI 10.1016/j.ejps.2010.11.016
   Teixeira PGR, 2008, AM SURGEON, V74, P891
   Tsuei BJ, 2004, AM SURGEON, V70, P652
   Turner JR, 2009, NAT REV IMMUNOL, V9, P799, DOI 10.1038/nri2653
   van Hensbroek PB, 2009, WORLD J SURG, V33, P199, DOI 10.1007/s00268-008-9867-3
   Vargo D, 2009, AM SURGEON, V75, pS1
   Verdam FJ, 2011, WORLD J SURG, V35, P2348, DOI 10.1007/s00268-011-1210-8
   Vertrees A, 2006, J AM COLL SURGEONS, V202, P762, DOI 10.1016/j.jamcollsurg.2006.02.008
   Wang GF, 2013, J TRAUMA ACUTE CARE, V74, P1175, DOI 10.1097/TA.0b013e318282705e
   Wondberg D, 2008, WORLD J SURG, V32, P2724, DOI 10.1007/s00268-008-9762-y
   Yuan YJ, 2013, J TRAUMA ACUTE CARE, V75, P266, DOI 10.1097/TA.0b013e3182924a63
   Yuan YJ, 2011, NUTR CLIN PRACT, V26, P688, DOI 10.1177/0884533611426148
   Yuan YJ, 2011, J TRAUMA, V71, P961, DOI 10.1097/TA.0b013e3181fa2932
NR 55
TC 15
Z9 18
U1 0
U2 16
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1687-6121
EI 1687-630X
J9 GASTROENT RES PRACT
JI Gastroenterol. Res. Pract.
PY 2013
VL 2013
AR 532013
DI 10.1155/2013/532013
PG 7
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA 234DV
UT WOS:000325621900001
PM 24198827
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Yoshida, S
   Yokoyama, R
   Sakamoto, A
AF Yoshida, Sei
   Yokoyama, Ryohei
   Sakamoto, Akio
TI TREATMENT OF PELVIC DEFECT AND INFECTION WITH ENDOPROSTHESIS EXPOSURE BY
   TOPICAL NEGATIVE PRESSURE AND IRRIGATION WITH MYOCUTANEOUS FLAP
SO MICROSURGERY
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; WOUND CONTROL; RECONSTRUCTION
AB The treatment of wound complications and deep infection after hemipelvectomy is challenging. We describe a 17-year-old woman with Ewing sarcoma in the pelvis who underwent hemipelvectomy and reconstruction with an artificial hip joint and bone cement. After the operation, skin necrosis and deep infection with methicillin-resistant Staphylococcus aureus (MRSA) were observed. Debridement resulted in exposure of the artificial joint and bone cement. Topical negative pressure (TNP) and irrigation successfully eradicated the infection. The skin and soft-tissue defect was subsequently reconstructed using a combination of free latissimus dorsi myocutaneous flap and serratus anterior muscle flap. To our knowledge, this is the first described case of combined TNP and irrigation with myocutaneous flap for the treatment of pelvic infection and skin and soft-tissue defect with endoprosthesis exposure. (C) 2011 Wiley Periodicals, Inc. Microsurgery 31: 655-658, 2011.
C1 [Sakamoto, Akio] Kyushu Univ, Grad Sch Med Sci, Dept Orthopaed Surg, Higashi Ku, Fukuoka 8128582, Japan.
   [Yoshida, Sei] Natl Hosp Org, Kyushu Canc Ctr, Dept Plast Surg, Fukuoka, Japan.
   [Yokoyama, Ryohei] Natl Hosp Org, Kyushu Canc Ctr, Dept Orthopaed Surg, Fukuoka, Japan.
C3 Kyushu University; Kyushu Cancer Center; Kyushu Cancer Center
RP Sakamoto, A (通讯作者)，Kyushu Univ, Grad Sch Med Sci, Dept Orthopaed Surg, Higashi Ku, 3-1-1 Maidashi, Fukuoka 8128582, Japan.
EM akio@med.kyushu-u.ac.jp
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Banwell P E, 1999, J Wound Care, V8, P79
   Cetrulo CL, 2008, MICROSURG, V28, P617, DOI 10.1002/micr.20578
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Harlan JW, 2002, PLAST RECONSTR SURG, V109, P710, DOI 10.1097/00006534-200202000-00045
   Hierner R, 2009, J PLAST RECONSTR AES, V62, P1692, DOI 10.1016/j.bjps.2008.07.038
   Jeys LM, 2008, J BONE JOINT SURG AM, V90A, P1265, DOI 10.2106/JBJS.F.01324
   Kelm J, 2009, INT J MED SCI, V6, P258
   Kelm J, 2009, INT J MED SCI, V6, P241
   Kiyokawa K, 2007, PLAST RECONSTR SURG, V120, P1257, DOI 10.1097/01.prs.0000279332.27374.69
   Knox K, 2006, ANN PLAS SURG, V57, P184, DOI 10.1097/01.sap.0000215288.83924.6c
   MATHES SJ, 1982, PLAST RECONSTR SURG, V69, P815, DOI 10.1097/00006534-198205000-00018
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Senchenkov A, 2008, ANN SURG ONCOL, V15, P355, DOI 10.1245/s10434-007-9672-5
   Senthi S, 2011, INT ORTHOP, V35, P253, DOI 10.1007/s00264-010-1144-z
   Tan KJ, 2010, J BONE JOINT SURG BR, V92B, P401, DOI 10.1302/0301-620X.92B3.22115
NR 16
TC 6
Z9 7
U1 0
U2 3
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 0738-1085
J9 MICROSURG
JI Microsurgery
PD NOV
PY 2011
VL 31
IS 8
BP 655
EP 658
DI 10.1002/micr.20932
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 851PN
UT WOS:000297283400011
PM 21919051
DA 2026-07-24
ER

PT J
AU Abad, C
   Safdar, N
AF Abad, C.
   Safdar, N.
TI From Ulcer to Infection: An Update on Clinical Practice and Adjunctive
   Treatments of Diabetic Foot Ulcers
SO CURRENT INFECTIOUS DISEASE REPORTS
LA English
DT Article
DE Diabetic foot infection; Diabetic foot ulcer; Antibiotics; G-CSF
ID COLONY-STIMULATING FACTOR; PRESSURE WOUND THERAPY; RANDOMIZED
   CONTROLLED-TRIAL; HYPERBARIC-OXYGEN THERAPY; SKIN-STRUCTURE INFECTIONS;
   VACUUM-ASSISTED CLOSURE; LOWER-EXTREMITY ULCERS; COMPLICATED SKIN;
   PIPERACILLIN-TAZOBACTAM; AMOXICILLIN-CLAVULANATE
AB Foot ulcers are a common complication of diabetes. A fifth of all individuals with diabetes develop a diabetic foot infection and are hospitalized at least once in their lifetime. Standard of care for treatment of diabetic foot ulcers and subsequent infection involves a multimodal, interdisciplinary team approach that includes wound care, systemic antimicrobials, and surgery. However, with the relatively poor outcome for chronic, longstanding ulcers and severe infections, recent research has focused on adjunctive therapies to promote wound healing and repair. This review summarizes the underlying pathology and classification of diabetic ulcers and focuses on recent advances that have important implications for the use of adjunctive therapy for diabetic foot infections.
C1 [Abad, C.] Milwaukee Hlth Serv Inc, Early Intervent Program Clin, Milwaukee, WI USA.
   [Safdar, N.] Univ Wisconsin, Sch Med & Publ Hlth, Dept Med, Infect Dis Sect, Madison, WI 53705 USA.
C3 University of Wisconsin System; University of Wisconsin Madison
RP Safdar, N (通讯作者)，Univ Wisconsin, Sch Med & Publ Hlth, Dept Med, Infect Dis Sect, MFCB 5221,1685 Highland Ave, Madison, WI 53705 USA.
EM ns2@medicine.wisc.edu
CR Abdulrazak A, 2005, J DIABETES COMPLICAT, V19, P138, DOI 10.1016/j.jdiacomp.2004.06.001
   Abidia A, 2003, EUR J VASC ENDOVASC, V25, P513, DOI 10.1053/ejvs.2002.1911
   Akbari A, 2007, J REHABIL RES DEV, V44, P631, DOI 10.1682/JRRD.2007.01.0002
   American Diabetes Association, 1999, Diabetes Care, V22, P1354
   [Anonymous], 6 EUR C ADV WOUND MA
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Argenta LC, 1997, ANN PLAST SURG, V38, P577
   Armstrong DG, 1998, DIABETES CARE, V21, P855, DOI 10.2337/diacare.21.5.855
   ARMSTRONG DG, 1995, J AM PODIAT MED ASSN, V85, P533, DOI 10.7547/87507315-85-10-533
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   ASFAR SK, 1993, CAN J SURG, V36, P170
   Bee TK, 2008, J TRAUMA, V65, P337, DOI 10.1097/TA.0b013e31817fa451
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Boulton AJM, 2000, DIABETES-METAB RES, V16, pS2, DOI 10.1002/1520-7560(200009/10)16:1+<::AID-DMRR105>3.0.CO;2-N
   Brismar K, 1997, Wound Repair Regen, V5, P147
   BROWN GL, 1979, AVIAT SPACE ENVIR MD, V50, P717
   Candel Gonzalez F J., 2003, Eur J Intern Med, V14, P341
   Citron DM, 2007, J CLIN MICROBIOL, V45, P2819, DOI 10.1128/JCM.00551-07
   Clay Patrick G, 2004, Am J Geriatr Pharmacother, V2, P181, DOI 10.1016/j.amjopharm.2004.09.006
   Crouzet J, 2011, INT J INFECT DIS, V15, pE601, DOI 10.1016/j.ijid.2011.05.003
   Cruciani M, 2009, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006810.pub2
   d'Hemecourt PA, 1998, WOUNDS, V10, P69
   DALE DC, 1995, J INFECT DIS, V172, P1061, DOI 10.1093/infdis/172.4.1061
   de Lalla F, 2001, ANTIMICROB AGENTS CH, V45, P1094, DOI 10.1128/AAC.45.4.1094-1098.2001
   Diaz Colodrero G, 1992, Enferm Infecc Microbiol Clin, V10, P451
   Doctor N, 1992, J Postgrad Med, V38, P112
   Edwards J, COCHRANE DATABASE SY
   Eginton MT, 2003, ANN VASC SURG, V17, P645, DOI 10.1007/s10016-003-0065-3
   El-Tahawy AT, 2000, SAUDI MED J, V21, P344
   Etöz A, 2004, WOUNDS, V16, P264
   Faglia E, 1996, DIABETES CARE, V19, P1338, DOI 10.2337/diacare.19.12.1338
   Frykberg R G, 2000, J Foot Ankle Surg, V39, pS1
   Frykberg R G, 1998, J Foot Ankle Surg, V37, P440
   Frykberg RG, 2002, AM FAM PHYSICIAN, V66, P1655
   Frykberg Robert G, 2006, J Foot Ankle Surg, V45, pS1
   Gardner SE, 2009, BIOL RES NURS, V11, P119, DOI 10.1177/1099800408326169
   Ge Y, 2002, DIABETIC MED, V19, P1032
   GERDING DN, 1995, CLIN INFECT DIS, V20, pS283, DOI 10.1093/clinids/20.Supplement_2.S283
   Giordano P, 2005, INT J ANTIMICROB AG, V26, P357, DOI 10.1016/j.ijantimicag.2005.07.017
   Goldstein EJC, 1996, DIABETES CARE, V19, P638, DOI 10.2337/diacare.19.6.638
   Gough A, 1997, LANCET, V350, P855, DOI 10.1016/S0140-6736(97)04495-4
   Graham DR, 2002, CLIN INFECT DIS, V35, P381, DOI 10.1086/341026
   Graham DR, 2002, CLIN INFECT DIS, V34, P1460, DOI 10.1086/340348
   GRAYSON ML, 1995, INFECT DIS CLIN N AM, V9, P143
   Harkless Lawrence, 2005, Surg Infect (Larchmt), V6, P27, DOI 10.1089/sur.2005.6.27
   Hartung T, 1999, AIDS, V13, pS3
   Huang WS, 2006, ASIAN J SURG, V29, P133
   HUNT JA, 1992, DIABETIC MED, V9, P749
   Jensen J L, 1998, Adv Wound Care, V11, P1
   Jones E W, 1985, Diabet Med, V2, P213
   Joseph W S, 1990, Clin Podiatr Med Surg, V7, P467
   Jull AB, 2008, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD005083.pub2
   Kästenbauer T, 2003, DIABETOLOGIA, V46, P27, DOI 10.1007/s00125-002-0998-z
   KUMAR S, 1994, DIABETIC MED, V11, P480, DOI 10.1111/j.1464-5491.1994.tb00310.x
   Lipsky BA, 2012, DIABETES-METAB RES, V28, P163, DOI 10.1002/dmrr.2248
   Lipsky B A, 1990, Infect Dis Clin North Am, V4, P409
   Lipsky BA, 2005, J ANTIMICROB CHEMOTH, V55, P240, DOI 10.1093/jac/dkh531
   Lipsky BA, 2004, CLIN INFECT DIS, V38, P17, DOI 10.1086/380449
   Lipsky BA, 2004, CLIN INFECT DIS, V39, P885, DOI 10.1086/383271
   Lipsky BA, 2005, LANCET, V366, P1695, DOI 10.1016/S0140-6736(05)67694-5
   Lipsky BA, 2007, J ANTIMICROB CHEMOTH, V60, P370, DOI 10.1093/jac/dkm130
   Lipsky BA, 2008, CLIN INFECT DIS, V47, P1537, DOI 10.1086/593185
   Löndahl M, 2011, DIABETOLOGIA, V54, P65, DOI 10.1007/s00125-010-1946-y
   Markevich YO, 2000, DIABETOLOGIA, V43, pA15
   MARX RE, 1990, AM J SURG, V160, P519, DOI 10.1016/S0002-9610(05)81019-0
   MASSON EA, 1989, DIABETIC MED, V6, P426, DOI 10.1111/j.1464-5491.1989.tb01198.x
   McCallon S K, 2000, Ostomy Wound Manage, V46, P28
   Mody GN, 2008, OSTOMY WOUND MANAG, V54, P36
   Moghazy AM, 2010, DIABETES RES CLIN PR, V89, P276, DOI 10.1016/j.diabres.2010.05.021
   Nelson S, 2000, J INFECT DIS, V182, P970, DOI 10.1086/315775
   Noel GJ, 2008, CLIN INFECT DIS, V46, P647, DOI 10.1086/526527
   O'Reilly D, TRIALS, V12, P69
   Oyibo SO, 2001, DIABETES CARE, V24, P84, DOI 10.2337/diacare.24.1.84
   Pathare N A, 1998, Indian J Pathol Microbiol, V41, P437
   Peck KR, 2001, J KOREAN MED SCI, V16, P39, DOI 10.3346/jkms.2001.16.1.39
   PECORARO RE, 1990, DIABETES CARE, V13, P513, DOI 10.2337/diacare.13.5.513
   PECORARO RE, 1991, DIABETES, V40, P1305, DOI 10.2337/diabetes.40.10.1305
   Perez D, 2010, AM J SURG, V199, P14, DOI 10.1016/j.amjsurg.2008.12.029
   Piaggesi A, 1998, DIABETIC MED, V15, P412, DOI 10.1002/(SICI)1096-9136(199805)15:5<412::AID-DIA584>3.0.CO;2-1
   Powlson AS, J ANTIMICROB CHEM S3, V65, piii3
   Reiber GE, 1999, DIABETES CARE, V22, P157, DOI 10.2337/diacare.22.1.157
   REIBER GE, 1992, ANN INTERN MED, V117, P97, DOI 10.7326/0003-4819-117-2-97
   RENG JJ, 1998, J SURG PATHOL, V3, P1
   ROTHMAN KJ, 1995, AM J EPIDEMIOL, V141, P90, DOI 10.1093/oxfordjournals.aje.a117417
   Rothman KJ, 1995, AM J EPIDEMIOL, V141, P89
   Saltoglu N, 2010, CLIN MICROBIOL INFEC, V16, P1252, DOI 10.1111/j.1469-0691.2009.03067.x
   SAPICO FL, 1984, REV INFECT DIS, V6, pS171
   SATO N, 1993, DIABETES, V42, P470, DOI 10.2337/diabetes.42.3.470
   Senneville E, 2006, CLIN INFECT DIS, V42, P57, DOI 10.1086/498112
   Sepúlveda G, 2009, CIR ESPAN, V86, P171, DOI 10.1016/j.ciresp.2009.03.020
   Shukrimi A, 2008, Med J Malaysia, V63, P44
   Siami G, 2001, ANTIMICROB AGENTS CH, V45, P525, DOI 10.1128/AAC.45.2.525-531.2001
   Sims D, 1984, J Foot Surg, V23, P149
   Stevens D. L., 1999, J Infect Chemother, V5, P40, DOI 10.1007/s101560050006
   Terashi H, KEIO J MED, V60, P17
   Ubbink DT, 2008, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001898.pub2
   Urbancic-Rovan V, 2000, DIABETIC MED, V17, P814, DOI 10.1046/j.1464-5491.2000.00374-2.x
   VEVES A, 1992, DIABETOLOGIA, V35, P660, DOI 10.1007/BF00400259
   Viswanathan V, 2003, J Assoc Physicians India, V51, P90
   Wagner FW, 1983, DIABETIC FOOT, P291
   Whalley A, 2001, 11 EUR TISS REP SOC, V49
   WHEAT LJ, 1986, ARCH INTERN MED, V146, P1935, DOI 10.1001/archinte.146.10.1935
   Xie X, J WOUND CARE, V19, P490
   Yönem A, 2001, DIABETES OBES METAB, V3, P332, DOI 10.1046/j.1463-1326.2001.00142.x
   YOUNG MJ, 1994, DIABETES CARE, V17, P557, DOI 10.2337/diacare.17.6.557
   YOUNG MJ, 1993, DIABETOLOGIA, V36, P150, DOI 10.1007/BF00400697
   YOUNG MJ, 1997, DIABETIC NEUROPATHY, P41
   Zeillemaker AM, 1998, FOOT ANKLE INT, V19, P169, DOI 10.1177/107110079801900311
NR 108
TC 5
Z9 10
U1 1
U2 26
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1523-3847
EI 1534-3146
J9 CURR INFECT DIS REP
JI Curr. Infect. Dis. Rep.
PD OCT
PY 2012
VL 14
IS 5
BP 540
EP 550
DI 10.1007/s11908-012-0283-3
PG 11
WC Infectious Diseases
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases
GA V32XH
UT WOS:000208983400010
PM 22903847
DA 2026-07-24
ER

PT J
AU Goyal, M
   Bains, A
   Singh, Y
   Deepali, F
   Singh, A
   Sood, S
   Buttar, NS
AF Goyal, Mayank
   Bains, Anmol
   Singh, Yadwinder
   Deepali, Fnu
   Singh, Anmol
   Sood, Shubham
   Buttar, Navtej S.
TI Endoscopic management of surgical complications
SO BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY
LA English
DT Article
DE Endoscopic suturing; Clips; Fistulas; Leaks; Perforation; Stent; Tissue
   adhesives; Surgical complications
ID VACUUM-ASSISTED CLOSURE; UPPER GASTROINTESTINAL-TRACT; ESOPHAGEAL STENT
   PLACEMENT; METAL STENTS; ENTEROCUTANEOUS FISTULAS; MULTICENTER
   EXPERIENCE; ANASTOMOTIC LEAKAGE; BARIATRIC SURGERY; TREATMENT OPTIONS;
   THERAPY
AB While the endoscopic management of surgical complications like leaks, fistulas, and perforations is rapidly evolving, its core principles revolve around closure, drainage, and containment. Effectively managing these conditions relies on several factors, such as the underlying cause, chronicity of the lesion, tissue viability, comorbidities, availability of devices, and expertise required to perform the endoscopy. In contrast to acute perforation, fistulas and leaks often demand a multimodal approach requiring more than one session to achieve the required results. Although the ultimate goal is complete resolution, these endoscopic interventions can provide clinical stability, enabling enteral feeding to lead to early hospital discharge or elective surgery. In this discussion, we emphasize the current state of knowledge and the prospective role of endoscopic interventions in managing surgical complications.
C1 [Goyal, Mayank; Bains, Anmol; Singh, Yadwinder; Deepali, Fnu; Singh, Anmol; Sood, Shubham; Buttar, Navtej S.] Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA.
   [Bains, Anmol] St Vincent Hosp, Worcester, MA USA.
   [Singh, Yadwinder] West Florida Hosp, HCA, Pensacola, FL USA.
   [Deepali, Fnu] Albert Einstein Med Ctr, Philadelphia, PA USA.
   [Singh, Anmol] Mercy St Vincent, Toledo, OH USA.
C3 Mayo Clinic; Hospital Corporation of America; Yeshiva University
RP Buttar, NS (通讯作者)，Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA.
EM Buttar.navtej@mayo.edu
CR Ahrens M, 2010, ENDOSCOPY, V42, P693, DOI 10.1055/s-0030-1255688
   Arezzo A, 2015, DIGEST LIVER DIS, V47, P342, DOI 10.1016/j.dld.2014.12.003
   Bakken JC, 2010, GASTROINTEST ENDOSC, V72, P712, DOI 10.1016/j.gie.2010.06.028
   Bège T, 2011, GASTROINTEST ENDOSC, V73, P238, DOI 10.1016/j.gie.2010.10.010
   Bick BL, 2013, GASTROINTEST ENDOSC, V77, P181, DOI 10.1016/j.gie.2012.10.004
   Böhm G, 2010, ENDOSCOPY, V42, P599, DOI 10.1055/s-0029-1244165
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Buchs NC, 2008, INT J COLORECTAL DIS, V23, P265, DOI 10.1007/s00384-007-0399-3
   Buttar NS, 2021, GASTROINTEST ENDOSC, V93, P1300, DOI 10.1016/j.gie.2020.12.048
   Campos ACL, 1999, J AM COLL SURGEONS, V188, P483, DOI 10.1016/S1072-7515(99)00038-1
   Connolly PT, 2008, ANN SURG, V247, P440, DOI 10.1097/SLA.0b013e3181612c99
   Dai YY, 2011, SEMIN THORAC CARDIOV, V23, P159, DOI 10.1053/j.semtcvs.2011.08.004
   David EA, 2011, AM J SURG, V202, P796, DOI 10.1016/j.amjsurg.2011.06.042
   Dionigi G, 2007, Int J Surg, V6, P51
   Dumonceau JM, 1999, GASTROINTEST ENDOSC, V49, P70, DOI 10.1016/S0016-5107(99)70448-7
   Eisendrath P, 2007, ENDOSCOPY, V39, P625, DOI 10.1055/s-2007-966533
   El Hajj II, 2014, GASTROINTEST ENDOSC, V79, P589, DOI 10.1016/j.gie.2013.08.039
   Fernandez-Esparrach G, 2010, SURG OBES RELAT DIS, V6, P282, DOI 10.1016/j.soard.2010.02.036
   Filgate R, 2015, SURG ENDOSC, V29, P2006, DOI 10.1007/s00464-014-3903-1
   Fischer A, 2007, DIS ESOPHAGUS, V20, P444, DOI 10.1111/j.1442-2050.2007.00652.x
   Fischer A, 2013, SURG ENDOSC, V27, P642, DOI 10.1007/s00464-012-2507-x
   Freeman RK, 2007, ANN THORAC SURG, V83, P2003, DOI 10.1016/j.athoracsur.2007.02.025
   Freeman RK, 2012, ANN THORAC SURG, V94, P959, DOI 10.1016/j.athoracsur.2012.05.047
   Freeman RK, 2011, ANN THORAC SURG, V92, P204, DOI 10.1016/j.athoracsur.2011.02.016
   Glitsch A, 2008, ENDOSCOPY, V40, P192, DOI 10.1055/s-2007-995384
   Grimaud JC, 2010, GASTROENTEROLOGY, V138, P2275, DOI 10.1053/j.gastro.2010.02.013
   Haffejee AA, 2004, CURR OPIN CLIN NUTR, V7, P309, DOI 10.1097/00075197-200405000-00011
   Haito-Chavez Y, 2014, GASTROINTEST ENDOSC, V80, P610, DOI 10.1016/j.gie.2014.03.049
   HALVERSEN RC, 1969, AM J SURG, V118, P968, DOI 10.1016/0002-9610(69)90268-2
   Herreros MD, 2012, DIS COLON RECTUM, V55, P762, DOI 10.1097/DCR.0b013e318255364a
   Hollington P, 2004, BRIT J SURG, V91, P1646, DOI 10.1002/bjs.4788
   Iossa A, 2016, LANGENBECK ARCH SURG, V401, P757, DOI 10.1007/s00423-016-1464-6
   Kirschniak A, 2007, GASTROINTEST ENDOSC, V66, P162, DOI 10.1016/j.gie.2007.01.034
   Kuehn F, 2012, J GASTROINTEST SURG, V16, P2145, DOI 10.1007/s11605-012-2014-3
   Kurokawa T, 2002, ENDOSCOPY, V34, P220, DOI 10.1055/s-2002-20294
   Lamazza A, 2014, AM J SURG, V208, P465, DOI 10.1016/j.amjsurg.2013.09.032
   LANGE V, 1990, SURG ENDOSC, V4, P212, DOI 10.1007/BF00316795
   Law R, 2015, SURG ENDOSC, V29, P1781, DOI 10.1007/s00464-014-3860-8
   Lee S, 2007, J GASTROINTEST SURG, V11, P708, DOI 10.1007/s11605-007-0085-3
   Lippert E, 2011, INT J COLORECTAL DIS, V26, P303, DOI 10.1007/s00384-010-1104-5
   Lloyd DAJ, 2006, BRIT J SURG, V93, P1045, DOI 10.1002/bjs.5396
   Lomis NNT, 2000, J AM COLL SURGEONS, V190, P588, DOI 10.1016/S1072-7515(00)00237-4
   Loske G, 2009, GASTROINTEST ENDOSC, V69, P601, DOI 10.1016/j.gie.2008.06.058
   Magdeburg R, 2008, SURG ENDOSC, V22, P1500, DOI 10.1007/s00464-007-9682-1
   Markar SR, 2013, ANN SURG ONCOL, V20, P4274, DOI 10.1245/s10434-013-3189-x
   Martinez JL, 2008, WORLD J SURG, V32, P436, DOI 10.1007/s00268-007-9304-z
   Mboumi IW, 2019, SURG CLIN N AM, V99, P501, DOI 10.1016/j.suc.2019.02.011
   Melmed GY, 2009, GASTROINTEST ENDOSC, V70, P542, DOI 10.1016/j.gie.2009.03.027
   Mennigen R, 2014, WORLD J GASTROENTERO, V20, P7767, DOI 10.3748/wjg.v20.i24.7767
   Minami S, 2006, GASTROINTEST ENDOSC, V63, P596, DOI 10.1016/j.gie.2005.07.029
   Narang SK, 2016, COLORECTAL DIS, V18, P37, DOI 10.1111/codi.13208
   O'Connor L, 2006, DIS COLON RECTUM, V49, P1569, DOI 10.1007/s10350-006-0695-y
   Orive-Calzada A, 2014, SURG LAPARO ENDO PER, V24, P528, DOI 10.1097/SLE.0b013e318293c4d8
   Puli SR, 2012, GASTROINTEST ENDOSC, V75, P287, DOI 10.1016/j.gie.2011.09.010
   Qadeer MA, 2007, GASTROINTEST ENDOSC, V66, P605, DOI 10.1016/j.gie.2007.03.1028
   Rábago LR, 2002, ENDOSCOPY, V34, P632, DOI 10.1055/s-2002-33237
   Rodella L, 1998, ENDOSCOPY, V30, P453, DOI 10.1055/s-2007-1001307
   Rutegård M, 2012, ANN SURG ONCOL, V19, P99, DOI 10.1245/s10434-011-1926-6
   Schaheen L, 2014, AM J SURG, V208, P536, DOI 10.1016/j.amjsurg.2014.05.011
   Schmidt A, 2014, ENDOSCOPY, V46, P762, DOI 10.1055/s-0034-1365493
   Schniewind B, 2013, SURG ENDOSC, V27, P3883, DOI 10.1007/s00464-013-2998-0
   Schorsch T, 2013, SURG ENDOSC, V27, P2040, DOI 10.1007/s00464-012-2707-4
   Schwandner O, 2008, INT J COLORECTAL DIS, V23, P319, DOI 10.1007/s00384-007-0398-4
   Seven G, 2013, SURG ENDOSC, V27, P2185, DOI 10.1007/s00464-012-2738-x
   Sharaiha RZ, 2016, J CLIN GASTROENTEROL, V50, P388, DOI 10.1097/MCG.0000000000000336
   Swinnen J, 2011, GASTROINTEST ENDOSC, V73, P890, DOI 10.1016/j.gie.2010.12.019
   Tabibian JH, 2016, GASTROINTEST ENDOSC, V83, P249, DOI 10.1016/j.gie.2015.08.006
   Tono Takeshi, 2014, Gan To Kagaku Ryoho, V41, P2500
   Van Assche G, 2010, J CROHNS COLITIS, V4, P63, DOI 10.1016/j.crohns.2009.09.009
   van Boeckel PGA, 2012, BMC GASTROENTEROL, V12, DOI 10.1186/1471-230X-12-19
   van Heel NCM, 2010, AM J GASTROENTEROL, V105, P1515, DOI 10.1038/ajg.2010.104
   Vikatmaa P, 2008, EUR J VASC ENDOVASC, V36, P438, DOI 10.1016/j.ejvs.2008.06.010
   Visschers RGJ, 2008, WORLD J SURG, V32, P445, DOI 10.1007/s00268-007-9371-1
   Wainstein DE, 2007, World J Surg, V32, P430
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Wedemeyer J, 2010, GASTROINTEST ENDOSC, V71, P382, DOI 10.1016/j.gie.2009.07.011
   Weidenhagen R, 2010, ANN THORAC SURG, V90, P1674, DOI 10.1016/j.athoracsur.2010.07.007
   Yoshikane H, 1997, GASTROINTEST ENDOSC, V46, P464, DOI 10.1016/S0016-5107(97)70045-2
NR 78
TC 0
Z9 0
U1 0
U2 4
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1521-6918
EI 1532-1916
J9 BEST PRACT RES CL GA
JI Best Pract. Res. Clin. Gastroenterol.
PD MAR
PY 2024
VL 69
AR 101898
DI 10.1016/j.bpg.2024.101898
EA MAY 2024
PG 9
WC Gastroenterology & Hepatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Gastroenterology & Hepatology
GA TL9S3
UT WOS:001241541100001
PM 38749577
DA 2026-07-24
ER

PT J
AU Aguilar, HA
   Mayer, HF
AF Aguilar, Hernan A.
   Mayer, Horacio F.
TI A New Method for Securing Dermal Substitutes and Skin Grafts to
   Difficult Portions of the Face Using a Custom 3D-Printed Facemask
SO JOURNAL OF BURN CARE & RESEARCH
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; MANAGEMENT; EXPERIENCE; BOLSTER
AB Management of third-degree facial burns remains one of the most difficult challenges in burn care. Patients with deep facial burns usually require gradual escharectomy, tangential excision of the wound, and resurfacing with full-thickness skin grafts or dermal substitutes associated with split-thickness skin grafts to provide better and superior cosmetic results. Immobilization of skin grafts and dermal substitutes by reducing shearing forces and hematoma formation underneath is paramount to improve success rates. Due to the irregular shape of the face, the proper immobilization of grafts with traditional methods is often difficult, especially over concave portions of the face. Herein, we report the original use of a custom three-dimensional printing facemask for securing dermal substitutes and skin grafts to difficult sites on the face.
C1 [Aguilar, Hernan A.; Mayer, Horacio F.] Univ Buenos Aires, Sch Med, Hosp Italiano Buenos Aires, Dept Plast Surg, Buenos Aires, DF, Argentina.
C3 University of Buenos Aires; University of Buenos Aires Hospital;
   Hospital Italiano de Buenos Aires
RP Aguilar, HA (通讯作者)，Hosp Italiano Buenos Aires, Peron 4190,1st Floor, RA-1181 Buenos Aires, DF, Argentina.
EM hernan.aguilar@hospitalitaliano.org.ar
RI Mayer, Horacio F/AAE-4645-2020
OI Mayer, Horacio F/0000-0002-3586-8657
CR Greenhalgh DG, 2013, J BURN CARE RES, V34, P576, DOI 10.1097/BCR.0b013e3182a22ea5
   Hummelink S, 2018, EUR J PLAST SURG, V41, P571, DOI 10.1007/s00238-018-1430-3
   Jackson SR, 2019, J BURN CARE RES, V40, P251, DOI 10.1093/jbcr/irz006
   Jacobo OM, 2018, EUR J PLAST SURG, V41, P137, DOI 10.1007/s00238-017-1373-0
   Kant SB, 2018, EUR J PLAST SURG, V41, P69, DOI 10.1007/s00238-017-1322-y
   Klein MB, 2005, BURNS, V31, P257, DOI 10.1016/j.burns.2004.11.013
   Kovacs L, 2006, IEEE T MED IMAGING, V25, P742, DOI 10.1109/TMI.2006.873624
   Kromka W, 2018, J CUTAN MED SURG, V22, P602, DOI 10.1177/1203475418782152
   Leon-Villapalos J, 2008, BURNS, V34, P903, DOI 10.1016/j.burns.2008.01.025
   Nguyen TQ, 2015, J BURN CARE RES, V36, P324, DOI 10.1097/BCR.0000000000000089
   Seol Young-Joon, 2018, Bioprinting, V10, pe00028, DOI [10.1016/j.bprint.2018.e00028, 10.1016/j.bprint.2018.e00028]
   Waltzman JT, 2014, J BURN CARE RES, V35, pE338, DOI 10.1097/BCR.0000000000000009
   Wei YT, 2018, BURNS, V44, P453, DOI 10.1016/j.burns.2017.08.006
   Wei Yating, 2017, Burns, V43, pe19, DOI [10.1016/j.burns.2016.08.034, 10.1016/j.burns.2016.08.034]
NR 14
TC 3
Z9 3
U1 0
U2 6
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1559-047X
EI 1559-0488
J9 J BURN CARE RES
JI J. Burn Care Res.
PD NOV-DEC
PY 2019
VL 40
IS 6
BP 1015
EP 1018
DI 10.1093/jbcr/irz128
PG 4
WC Critical Care Medicine; Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Dermatology; Surgery
GA JL2NG
UT WOS:000495368300043
PM 31290964
DA 2026-07-24
ER

PT J
AU Sinha, S
AF Sinha, Sankar
TI Management of post-surgical wounds in general practice
SO AUSTRALIAN JOURNAL OF GENERAL PRACTICE
LA English
DT Editorial Material
ID ULCERS
AB Background
   The availability of complex wound dressings following progressive innovations, increasing demand for hospital beds and the early discharge of post-operative patients have shifted the sharing of care of such patients from hospital specialists to general practitioners (GPs). Although several published guidelines on the management of chronic wounds exist, there is a lack of similar material addressing the assessment and management of post-surgical wounds.
   Objective
   The aim of this article is to provide a practical guideline for identifying early complications of post-surgical wounds and managing patients with complex wound dressing systems such as vacuum-assisted closure.
   Discussion
   Early detection of wound complications is crucial to improving patients' quality of life and reducing hospital readmission. GP competency in the proper application of complex dressings is one component that can improve these factors. Effective communication, including documentation, between hospitals, community nurses and GPs ensures smooth management of wound care for patients.
C1 [Sinha, Sankar] Univ Tasmania, Wound Care Surg, Hobart, Tas, Australia.
   [Sinha, Sankar] Univ Notre Dame Australia, Sch Med, Anat, Fremantle, WA, Australia.
C3 University of Tasmania; The University of Notre Dame Australia
RP Sinha, S (通讯作者)，Univ Tasmania, Wound Care Surg, Hobart, Tas, Australia.; Sinha, S (通讯作者)，Univ Notre Dame Australia, Sch Med, Anat, Fremantle, WA, Australia.
EM sankar.sinha@utas.edu.au
CR [Anonymous], 2012, WOUNDS K
   Applewhite Andrew, 2018, Wounds, V30, pS19
   Ban KA, 2017, J AM COLL SURGEONS, V224, P59, DOI 10.1016/j.jamcollsurg.2016.10.029
   EHRENKRANZ NJ, 1990, J CLIN MICROBIOL, V28, P2389, DOI 10.1128/JCM.28.11.2389-2393.1990
   Gillespie BM, 2014, J CLIN NURS, V23, P3250, DOI 10.1111/jocn.12574
   Gupta S, 2017, WOUNDS, pS19
   Harrington Pauline, 2014, Nurs Stand, V28, P50, DOI 10.7748/ns.28.48.50.e8958
   Lim K, 2015, J WOUND CARE, V24
   Macefield R, 2019, BJS-BRIT J SURG, V106, P226, DOI 10.1002/bjs.11008
   McCarthy SM, 2010, MED J AUSTRALIA, V193, P252, DOI 10.5694/j.1326-5377.2010.tb03898.x
   Peart J., 2019, WOUNDS UK, V15, P20
   Rochon M., 2016, Wounds UK, V12, P26
   Sinha S, 2014, AUST FAM PHYSICIAN, V43, P594
   Ubbink DT, 2015, ADV WOUND CARE, V4, P286, DOI 10.1089/wound.2014.0592
   Webster J, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub4
   Weiss EA, 2013, BMJ OPEN, V3, DOI 10.1136/bmjopen-2012-001504
   Whitlock E, 2014, AUST FAM PHYSICIAN, V43, P143
   WINTER GD, 1962, NATURE, V193, P293, DOI 10.1038/193293a0
   Yao KH, 2013, AUST FAM PHYSICIAN, V42, P867
NR 19
TC 22
Z9 30
U1 0
U2 11
PU ROYAL AUSTRALIAN COLLEGE GENERAL PRACTITIONERS
PI SOUTH MELBOURNE
PA 1 PALMERSTON CRESCENT, SOUTH MELBOURNE, VICTORIA 3205, AUSTRALIA
SN 2208-794X
EI 2208-7958
J9 AUST J GEN PRACT
JI Aust. J. Gen. Pract.
PD SEP
PY 2019
VL 48
IS 9
BP 596
EP 599
DI 10.31128/AJGP-04-19-4921
PG 4
WC Primary Health Care; Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA IV0SH
UT WOS:000483988400006
PM 31476832
DA 2026-07-24
ER

PT J
AU Braun, G
   Muck, A
AF Braun, Georg
   Muck, Alexander
TI Endoscopy on the surgical intensive care unit
SO ANAESTHESIST
LA German
DT Article
DE Enteral nutrition; Tube feeding; Endoscopic vacuum therapy; Anastomotic
   leakage; Endoscopic decompression
ID VACUUM-ASSISTED CLOSURE; ANASTOMOTIC LEAKAGE; GERMAN SOCIETY; THERAPY;
   ESOPHAGEAL; GASTROENTEROLOGY; RESECTION; DRAINAGE
AB Endoscopy is most frequently performed in intensive care units (ICU) for gastrointestinal bleeding; however, there are other indications for performing an endoscopy on the ICU. This article shows the indications for this, the background and the peri-interventional and postinterventional management. The endoscopic placement of a postpyloric feeding tube is a well-established procedure. For anastomotic leakage in the esophagus and rectum, the endoscopic vacuum therapy is the treatment of choice. Gastrointestinal motility disorders are a frequent phenomenon in critically ill patients and are associated with increased mortality. With a cecal diameter > 9-12 mm, endoscopic decompression can be performed; however, this is associated with an increased risk of perforation and should only be carried out after the failure of conservative treatment.
C1 [Braun, Georg; Muck, Alexander] Univ Klinikum Augsburg, Klin Anasthesiol & Operat Intens Med, Medi Klin 3, Stenglinstr 2, D-86156 Augsburg, Germany.
RP Braun, G (通讯作者)，Univ Klinikum Augsburg, Klin Anasthesiol & Operat Intens Med, Medi Klin 3, Stenglinstr 2, D-86156 Augsburg, Germany.
EM georg.braun@uk-augsburg.de
CR Ahrens M, 2010, ENDOSCOPY, V42, P693, DOI 10.1055/s-0030-1255688
   Alkhawaja S, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008875.pub2
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Blaser AR, 2017, INTENS CARE MED, V43, P380, DOI 10.1007/s00134-016-4665-0
   Bludau M, 2018, SURG ENDOSC, V32, P1906, DOI 10.1007/s00464-017-5883-4
   Brangewitz M, 2013, ENDOSCOPY, V45, P433, DOI 10.1055/s-0032-1326435
   Chopra SS, 2009, SURGERY, V145, P182, DOI 10.1016/j.surg.2008.09.012
   Elke G, 2019, CLIN NUTR ESPEN, V33, P220, DOI 10.1016/j.clnesp.2019.05.002
   European Assoc Study Liver, 2018, J HEPATOL, V69, P406, DOI 10.1016/j.jhep.2018.03.024
   Goenka MK, 2015, WORLD J GASTRO ENDOS, V7, P702, DOI 10.4253/wjge.v7.i7.702
   Götz M, 2017, Z GASTROENTEROL, V55, P1499, DOI 10.1055/s-0043-120351
   Götz M, 2017, Z GASTROENTEROL, V55, P883, DOI 10.1055/s-0043-116856
   Gralnek IM., 2015, ENDOSCOPY, DOI 10.1055/s-0034-1393172
   Gubler C, 2019, DIS ESOPHAGUS, V32, DOI 10.1093/dote/doy126
   Keller J, 2015, MED KLIN-INTENSIVMED, V110, P506, DOI 10.1007/s00063-015-0081-4
   Kühn F, 2020, WORLD J SURG, V44, P1277, DOI 10.1007/s00268-019-05349-5
   Leeds SG, 2019, J GASTROINTEST SURG, V23, P1037, DOI 10.1007/s11605-018-04082-z
   Leppkes M, 2015, MED KLIN-INTENSIVMED, V110, P500, DOI 10.1007/s00063-015-0076-1
   Loske G, 2009, ZBL CHIR, V134, P267, DOI 10.1055/s-0028-1098764
   Loske G, 2010, SURG ENDOSC, V24, P2531, DOI 10.1007/s00464-010-0998-x
   Loske G, 2009, GASTROINTEST ENDOSC, V69, P601, DOI 10.1016/j.gie.2008.06.058
   Mees ST, 2008, DIS COLON RECTUM, V51, P404, DOI 10.1007/s10350-007-9141-z
   Mencio MA, 2018, SURG ENDOSC, V32, P3349, DOI 10.1007/s00464-018-6055-x
   Mennigen R, 2014, WORLD J GASTROENTERO, V20, P7767, DOI 10.3748/wjg.v20.i24.7767
   Nagell CF, 2006, INT J COLORECTAL DIS, V21, P657, DOI 10.1007/s00384-005-0083-4
   Oakland K, 2019, GUT, V68, P776, DOI 10.1136/gutjnl-2018-317807
   Reintam A, 2008, CRIT CARE, V12, DOI 10.1186/cc6958
   Ryan CE, 2017, ANN SURG ONCOL, V24, P281, DOI 10.1245/s10434-016-5417-7
   Schniewind B, 2013, SURG ENDOSC, V27, P3883, DOI 10.1007/s00464-013-2998-0
   Shalaby M, 2019, BJS OPEN, V3, P153, DOI 10.1002/bjs5.50124
   Singer P, 2019, CLIN NUTR, V38, P48, DOI 10.1016/j.clnu.2018.08.037
   Smedley LW, 2020, J INTENSIVE CARE MED, V35, P1039, DOI 10.1177/0885066618809010
   Still S, 2018, ANN THORAC CARDIOVAS, V24, P173, DOI 10.5761/atcs.oa.17-00107
   Szymanski K, 2018, CASE REP SURG, V2018, DOI 10.1155/2018/2494069
   van Koperen PJ, 2009, SURG ENDOSC, V23, P1379, DOI 10.1007/s00464-008-0186-4
   Virgilio E, 2018, ANTICANCER RES, V38, P5581, DOI 10.21873/anticanres.12892
   Wallstabe I, 2010, ENDOSCOPY, V42, pE165, DOI 10.1055/s-0029-1244150
   Ward MA, 2019, SURG ENDOSC, V33, P3970, DOI 10.1007/s00464-019-06685-2
   Wedemeyer J, 2008, GASTROINTEST ENDOSC, V67, P708, DOI 10.1016/j.gie.2007.10.064
   Weidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-x
NR 40
TC 1
Z9 1
U1 0
U2 1
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0003-2417
EI 1432-055X
J9 ANAESTHESIST
JI Anaesthesist
PD NOV
PY 2021
VL 70
IS 11
SI SI
BP 977
EP 990
DI 10.1007/s00101-021-01047-x
EA OCT 2021
PG 14
WC Anesthesiology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Anesthesiology
GA WR2YB
UT WOS:000712177000002
PM 34709412
DA 2026-07-24
ER

PT J
AU Szkorupa, M
   Chudacek, J
   Klementová, O
   Neoral, C
   Stasek, M
AF Szkorupa, Marek
   Chudacek, Josef
   Klementova, Olga
   Neoral, Cestmir
   Stasek, Martin
TI Early simultaneous esophagopleural and bronchopleural fistula after
   right pneumonectomy
SO ACTA CHIRURGICA BELGICA
LA English
DT Article
DE esophageal fistula; pneumonectomy; postoperative complication; lung
   neoplasm
ID EMPYEMA
AB Background: Esophagopleural and bronchopleural fistulas represent a rare, but life-threatening complication after lung resections, most often after a right pneumonectomy.
   Case study: A 64 years old woman was indicated for right pulmectomy for local recurrence of initially stage IIB lung cancer treated by lower lobectomy. On the postoperative day 34, an esophagopleurobronchial fistula occurred. Further course required thoracostomy with closure of the bronchial stump and vacuum-assisted closure therapy and two-phase esophagectomy with 6 weeks interval to the esophageal reconstruction. Patient represents 2 years of disease-free survival with good functional results.
   Conclusion: The therapy of esophagopleural and bronchopleural fistula is long-term and complicated, requiring a multidisciplinary approach and several basic principles must be adhered to the management including treatment of infection and prevention of sepsis, local treatment of the fistula and pleural empyema, and adequate ventilation and nutritive care.
C1 [Szkorupa, Marek; Chudacek, Josef; Neoral, Cestmir; Stasek, Martin] Palacky Univ Olomouc, Univ Hosp Olomouc, Fac Med & Dent, Dept Surg 1, Olomouc, Czech Republic.
   [Klementova, Olga] Palacky Univ Olomouc, Univ Hosp Olomouc, Fac Med & Dent, Dept Anesthesiol & Intens Care Med, IP Pavlova 6, Olomouc 77520, Czech Republic.
C3 Palacky University Olomouc; University Hospital Olomouc; Palacky
   University Olomouc; University Hospital Olomouc
RP Klementová, O (通讯作者)，Palacky Univ Olomouc, Univ Hosp Olomouc, Fac Med & Dent, Dept Anesthesiol & Intens Care Med, IP Pavlova 6, Olomouc 77520, Czech Republic.
EM saol@email.cz
RI /ABH-5345-2020; Stašek, Martin/AAB-4435-2020
OI Neoral, Čestmír/0000-0001-8912-8155; Stašek, Martin/0000-0002-1308-7390
CR Dosios T, 2005, DIS ESOPHAGUS, V18, P202, DOI 10.1111/j.1442-2050.2005.00472.x
   EVANS JP, 1972, THORAX, V27, P674, DOI 10.1136/thx.27.6.674
   Kim TH, 2014, J VASC INTERV RADIOL, V25, P623, DOI 10.1016/j.jvir.2013.12.015
   Klepetko W, 1999, EUR J CARDIO-THORAC, V15, P758, DOI 10.1016/S1010-7940(99)00089-5
   MASSARD G, 1994, ANN THORAC SURG, V58, P1437, DOI 10.1016/0003-4975(94)91930-5
   Renner C, 2010, ANN THORAC SURG, V89, P603, DOI 10.1016/j.athoracsur.2009.06.037
   SETHI GK, 1978, ANN THORAC SURG, V25, P74, DOI 10.1016/S0003-4975(10)63492-3
   Stolz A, 2010, COMPLICATIONS LUNG S
   Trigui W, 2002, ANN THORAC SURG, V74, P923, DOI 10.1016/S0003-4975(02)03673-1
   Zaheer S, 2006, ANN THORAC SURG, V82, P279, DOI 10.1016/j.athoracsur.2006.01.052
NR 10
TC 2
Z9 4
U1 0
U2 3
PU ACTA MEDICAL BELGICA
PI BRUSSELS
PA AVENUE CIRCULAIRE 138 A, B-1180 BRUSSELS, BELGIUM
SN 0001-5458
J9 ACTA CHIR BELG
JI Acta Chir. Belg.
PY 2018
VL 118
IS 1
BP 56
EP 58
DI 10.1080/00015458.2017.1300006
PG 3
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GC9BD
UT WOS:000430091600010
PM 28460565
DA 2026-07-24
ER

PT J
AU Reichert, B
AF Reichert, B
TI Optimizing delayed reconstruction of complex pressure sores by VAC®
   therapy
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Nations Congress
CY 2003
CL Nuernberg, GERMANY
DE decubitus ulcer; pressure sore; vacuum assisted closure
ID ULCER RISK-FACTORS; DECUBITUS ULCERS; MYOCUTANEOUS FLAPS; MANAGEMENT;
   COVERAGE; SURGERY; CLOSURE; TRIAL
AB V.A.C.(R)-therapy has improved the treatment of extended pressure sores, because of its beneficial effect on the wound surface and the safe microbial barrier. Definitive reconstructive surgery can be performed earlier. Using modern aids fixation of the device will be possible even in difficult locations as the perianal area. This is important for immobile and multimorbid patients. On the other hand, this area still shows limitations of the method. In recurrent cases it is difficult to use classical methods of reconstruction. Long-term-treatment is necessary, which is economically difficult. It is important for hospitals to cooperate with specialised wound therapeutics so that these patients can be dismissed earlier. This may allow reconstructive procedures, even if this takes several hospital stays over a long period of time.
C1 Klinikum Nurnberg Sud, Zentrum Schwerbrandverletzte, Klin Plast Wiederherstellende & Handchirurg, D-90471 Nurnberg, Germany.
RP Reichert, B (通讯作者)，Klinikum Nurnberg Sud, Zentrum Schwerbrandverletzte, Klin Plast Wiederherstellende & Handchirurg, Breslauer Str 201, D-90471 Nurnberg, Germany.
EM bert.reichert@klinikum-nuernberg.de
CR ALLMAN RM, 1995, JAMA-J AM MED ASSOC, V273, P865, DOI 10.1001/jama.273.11.865
   Ankrom Michael A, 2005, Adv Skin Wound Care, V18, P35, DOI 10.1097/00129334-200501000-00016
   [Anonymous], 2003, Cochrane Database of Systematic Reviews
   Bansal C, 2005, INT J DERMATOL, V44, P805, DOI 10.1111/j.1365-4632.2005.02636.x
   Berlowitz Dan R, 2005, Adv Skin Wound Care, V18, P480, DOI 10.1097/00129334-200511000-00011
   CAMPBELL RM, 1977, PLASTIC RECONSTRUCTI, P3763
   CONWAY H, 1956, AM J SURG, V91, P946, DOI 10.1016/0002-9610(56)90327-0
   DANIEL RK, 1982, ANN PLAS SURG, V8, P446, DOI 10.1097/00000637-198206000-00002
   Desneves KJ, 2005, CLIN NUTR, V24, P979, DOI 10.1016/j.clnu.2005.06.011
   Ford CN, 2002, ANN PLAS SURG, V49, P55, DOI 10.1097/00000637-200207000-00009
   Gardner SE, 2005, J GERONTOL A-BIOL, V60, P93, DOI 10.1093/gerona/60.1.93
   Gawron C L, 1994, J Wound Ostomy Continence Nurs, V21, P232
   GER R, 1971, SURGERY, V69, P106
   LINDAN O, 1965, ARCH PHYS MED REHAB, V46, P375
   Lindgren M, 2005, J ADV NURS, V50, P605, DOI 10.1111/j.1365-2648.2005.03441.x
   Reichert B, 1996, ZBL CHIR, V121, P83
   Schoeller T, 2003, CHIRURG, V74, P671, DOI 10.1007/s00104-003-0668-9
   Smith Noleen, 2004, Br J Nurs, V13, P1359
   Stratton RJ, 2005, AGEING RES REV, V4, P422, DOI 10.1016/j.arr.2005.03.005
   Warbanow K, 1997, LANGENBECK ARCH CHIR, V382, P359
NR 20
TC 1
Z9 1
U1 0
U2 2
PU JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
PI STUTTGART
PA RUEDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD APR
PY 2006
VL 131
SU 1
BP S24
EP S28
DI 10.1055/s-2006-921448
PG 5
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 034DB
UT WOS:000236904100007
PM 16575640
DA 2026-07-24
ER

PT J
AU Steiert, AE
   Partenheimer, A
   Schreiber, T
   Muehlberger, T
   Krettek, C
   Lahoda, LU
   Vogt, PM
AF Steiert, AE
   Partenheimer, A
   Schreiber, T
   Muehlberger, T
   Krettek, C
   Lahoda, LU
   Vogt, PM
TI The VAC® system (Vacuum Assisted Closure) as bridging between primary
   osteosynthesis in conjunction with functional reconstructed of soft
   tissue -: Open fractures type 2 and type 3
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Country Congress on VAC Therapy for Outpatients as well as
   In-Hospital Patients
CY MAY 21-22, 2003
CL Mainz, GERMANY
AB Open fractures are complex injuries affecting the integrity of bones and adjacent soft tissue. The therapeutic goals in dealing with open fractures should consist of primary osteosynthesis in conjunction with functional reconstruction of soft tissue. In a period over 2 years, 26 patients were treated with extensive trauma in an interdisciplinary approach. These patients suffered from open fractures type 2 and 3. All patients were treated by primary osteosynthesis, and temporary wound closure with V.A.C.(R)-system. Definitive wound closure was achieved by day 31 after injury.
   In contrast to a review of the pertinent literature we report the successful free tissue transfer in 21 patients during the critical period [2] between 72 hours and several months preceded by the use of V.A.C.(R)-system for the temporary coverage of open Wounds.
C1 Hannover Med Sch, Klinikum Hannover Oststadt, Klin Plast Hand & Wiederherstellungschirurg, Unfallchirurg Klin, D-30659 Hannover, Germany.
C3 Hannover Medical School
RP Steiert, AE (通讯作者)，Hannover Med Sch, Klinikum Hannover Oststadt, Klin Plast Hand & Wiederherstellungschirurg, Unfallchirurg Klin, Podbielskistr 380, D-30659 Hannover, Germany.
EM andreas.steiert.oststadt@klinikum-hannover.de
RI ; Vogt, Peter/AAL-1332-2020
OI Krettek, Christian/0000-0001-9807-0020; 
CR GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Gopal S, 2000, J BONE JOINT SURG BR, V82B, P959, DOI 10.1302/0301-620X.82B7.10482
NR 2
TC 8
Z9 8
U1 0
U2 0
PU JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
PI STUTTGART
PA RUEDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0044-409X
J9 ZBL CHIR
JI Zent.bl. Chir.
PD MAY
PY 2004
VL 129
SU 1
BP S98
EP S100
DI 10.1055/s-2004-822658
PG 3
WC Surgery
WE Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 826GF
UT WOS:000221816600031
PM 15168301
DA 2026-07-24
ER

PT J
AU Elsayed, NA
   Aleppo, G
   Bannuru, RR
   Bruemmer, D
   Collins, BS
   Ekhlaspour, L
   Gibbons, CH
   Giurini, JM
   Hilliard, ME
   Johnson, EL
   Khunti, K
   Lingvay, I
   Matfin, G
   McCoy, RG
   Perry, ML
   Pilla, SJ
   Polsky, S
   Prahalad, P
   Pratley, RE
   Segal, AR
   Seley, JJ
   Silva, PS
   Stanton, RC
   Gabbay, RA
   Beverly, EA
   Cusi, K
   Darville, A
   Das, SR
   Fleming, TK
   Gaglia, JL
   Galindo, RJ
   Hassanein, M
   Kosiborod, MN
   Kushner, RF
   Murdock, L
   Napoli, N
   Selvin, E
   Silva, PS
   Verduzco-Gutierrez, M
   Woodward, CC
   Younossi, ZM
   Pekas, EJ
   Yacoubian, AM
AF Elsayed, Nuha A.
   Aleppo, Grazia
   Bannuru, Raveendhara R.
   Bruemmer, Dennis
   Collins, Billy S.
   Ekhlaspour, Laya
   Gibbons, Christopher H.
   Giurini, John M.
   Hilliard, Marisa E.
   Johnson, Eric L.
   Khunti, Kamlesh
   Lingvay, Ildiko
   Matfin, Glenn
   McCoy, Rozalina G.
   Perry, Mary Lou
   Pilla, Scott J.
   Polsky, Sarit
   Prahalad, Priya
   Pratley, Richard E.
   Segal, Alissa R.
   Seley, Jane Jeffrie
   Silva, Paolo S.
   Stanton, Robert C.
   Gabbay, Robert A.
   Beverly, Elizabeth A.
   Cusi, Kenneth
   Darville, Audrey
   Das, Sandeep R.
   Fleming, Talya K.
   Gaglia, Jason L.
   Galindo, Rodolfo J.
   Hassanein, Mohamed
   Kosiborod, Mikhail N.
   Kushner, Robert F.
   Murdock, Lisa
   Napoli, Nicola
   Selvin, Elizabeth
   Silva, Paolo S.
   Verduzco-Gutierrez, Monica
   Woodward, Crystal C.
   Younossi, Zobair M.
   Pekas, Elizabeth J.
   Yacoubian, Alexandra M.
CA Amer Diabetes Assoc Professional
TI 12. Retinopathy, Neuropathy, and Foot Care: Standards of Care in
   Diabetes-2024
SO DIABETES CARE
LA English
DT Review
ID DIABETIC PERIPHERAL NEUROPATHY; QUALITY-OF-LIFE;
   CONTROL-CARDIOVASCULAR-RISK; INTENSIVE INSULIN THERAPY;
   HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED CLOSURE; COMPLICATIONS
   TRIAL/EPIDEMIOLOGY; DOUBLE-BLIND; PANRETINAL PHOTOCOAGULATION;
   ORTHOSTATIC HYPOTENSION
AB The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
EM rbannuru@diabetes.org
RI ; Bannuru, Raveendhara/G-2601-2011; Fleming, Talya/ABC-5204-2021;
   Lingvay, Ildiko/AGL-9548-2022; Cusi, Kenneth/ADV-2401-2022; Selvin,
   Elizabeth/LTE-9727-2024; Polsky, Sarit/AAT-3067-2020; Younossi, Zobair
   M./JRY-9916-2023; /GQB-2573-2022; Kosiborod, Mikhail/HDO-1541-2022;
   Silva, Paolo/KTI-0008-2024; Giurini, John/LZH-7752-2025; Galindo,
   Rodolfo/V-7010-2019; Gabbay, Robert/KLC-9779-2024
OI ElSayed, Nuha/0000-0003-1217-4916; Bannuru,
   Raveendhara/0000-0002-8069-5783; Segal, Alissa/0000-0003-4895-9598; 
FU NIDDK NIH HHS [K23 DK121942] Funding Source: Medline
CR Abràmoff MD, 2018, NPJ DIGIT MED, V1, DOI 10.1038/s41746-018-0040-6
   Afshinnia F, 2022, ANN CLIN TRANSL NEUR, V9, P1392, DOI 10.1002/acn3.51639
   Agardh E, 2011, DIABETES CARE, V34, P1318, DOI 10.2337/dc10-2308
   Aiello LP, 2015, NEW ENGL J MED, V372, P1722, DOI 10.1056/NEJMoa1409463
   Albers JW, 2010, DIABETES CARE, V33, P1090, DOI 10.2337/dc09-1941
   Albers JW, 1995, ANN NEUROL, V38, P869, DOI 10.1002/ana.410380607
   Andersen ST, 2018, DIABETES CARE, V41, P1068, DOI 10.2337/dc17-2062
   Ang L, 2014, CURR DIABETES REP, V14, P1, DOI 10.1007/s11892-014-0528-7
   [Anonymous], 1976, Am J Ophthalmol, V81, P383
   [Anonymous], 1985, Arch Ophthalmol, V103, P1796, DOI 10.1001/archopht.1985.01050120030015
   [Anonymous], 2022, National Diabetes Statistics Report website
   [Anonymous], 2018, FDA permits marketing of artificial intelligence algorithm for aiding providers in detecting wrist fractures
   Argenta LC, 2006, PLAST RECONSTR SURG, V117, p127S, DOI 10.1097/01.prs.0000222551.10793.51
   Baker CW, 2019, JAMA-J AM MED ASSOC, V321, P1880, DOI 10.1001/jama.2019.5790
   Barbano RL, 2004, ARCH NEUROL-CHICAGO, V61, P914, DOI 10.1001/archneur.61.6.914
   Bashir M, 2021, DIAB MET SYND CLIN R, V15, DOI 10.1016/j.dsx.2021.102241
   Bethel MA, 2021, DIABETES CARE, V44, P290, DOI 10.2337/dc20-1815
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Boulton AJM, 2022, New Evidence-Based Therapies for Complex Diabetic Foot Wounds, American Diabetes Association © 2022 by American Diabetes Association. All rights reserved. None of the contents may be reproduced without the written permission of the American Diabetes Association, V2022, P1
   Boulton AJM, 2008, DIABETES CARE, V31, P1679, DOI 10.2337/dc08-9021
   Bragge P, 2011, ARCH OPHTHALMOL-CHIC, V129, P435, DOI 10.1001/archophthalmol.2010.319
   Briasoulis A, 2014, J CLIN HYPERTENS, V16, P141, DOI 10.1111/jch.12258
   Bus SA, 2016, DIABETES-METAB RES, V32, P99, DOI 10.1002/dmrr.2702
   Bus SA, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3269
   Callaghan BC, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD007543.pub2
   Callaghan BC, 2021, OBESITY, V29, P2108, DOI 10.1002/oby.23246
   Callaghan BC, 2016, DIABETES CARE, V39, P801, DOI 10.2337/dc16-0081
   Camilleri M, 2013, AM J GASTROENTEROL, V108, P18, DOI 10.1038/ajg.2012.373
   Carter MJ, 2023, ADV WOUND CARE, V12, P177, DOI 10.1089/wound.2022.0041
   Chew EY, 2014, OPHTHALMOLOGY, V121, P2443, DOI 10.1016/j.ophtha.2014.07.019
   Chew EY, 2010, NEW ENGL J MED, V363, P233, DOI 10.1056/NEJMoa1001288
   Conte MS, 2019, EUR J VASC ENDOVASC, V58, pS1, DOI 10.1016/j.ejvs.2019.05.006
   Dabelea D, 2017, JAMA-J AM MED ASSOC, V317, P825, DOI 10.1001/jama.2017.0686
   Daskivich LP, 2017, JAMA INTERN MED, V177, P642, DOI 10.1001/jamainternmed.2017.0204
   Diabet Control Complications Trial Res Grp, 1998, DIABETOLOGIA, V41, P416
   Diabetes Control and Complications, 2000, DIABETES CARE, V23, P1084
   Dworkin RH, 2007, J PAIN, V8, P118, DOI 10.1016/j.jpain.2006.06.005
   Eid S, 2019, DIABETOLOGIA, V62, P1539, DOI 10.1007/s00125-019-4959-1
   Elman MJ, 2011, OPHTHALMOLOGY, V118, P609, DOI 10.1016/j.ophtha.2010.12.033
   Estacio RO, 1998, AM J KIDNEY DIS, V31, P947, DOI 10.1053/ajkd.1998.v31.pm9631838
   Fedorko L, 2016, DIABETES CARE, V39, P392, DOI 10.2337/dc15-2001
   Figueroa JJ, 2010, CLEV CLIN J MED, V77, P298, DOI 10.3949/ccjm.77a.09118
   Freeman R, 2009, CURR DIABETES REP, V9, P423, DOI 10.1007/s11892-009-0069-7
   Frykberg RG, 2022, DIABETES CARE, V45, pE144, DOI 10.2337/dc22-1111
   Frykberg RG, 2021, MEDICINA-LITHUANIA, V57, DOI 10.3390/medicina57090917
   Frykberg RG, 2020, DIABETES CARE, V43, P616, DOI 10.2337/dc19-0476
   Frykberg RG, 2015, ADV WOUND CARE, V4, P560, DOI 10.1089/wound.2015.0635
   Goodall RJ, 2020, EUR J VASC ENDOVASC, V60, P282, DOI 10.1016/j.ejvs.2020.03.053
   Gross JG, 2015, JAMA-J AM MED ASSOC, V314, P2137, DOI 10.1001/jama.2015.15217
   Gubitosi-Klug RA, 2016, JAMA OPHTHALMOL, V134, P137, DOI 10.1001/jamaophthalmol.2015.4606
   Gunderson EP, 2007, DIABETES, V56, P2990, DOI 10.2337/db07-1024
   Heng ML, 2020, INT WOUND J, V17, P1678, DOI 10.1111/iwj.13450
   Hingorani A, 2016, J VASC SURG, V63, p3S, DOI 10.1016/j.jvs.2015.10.003
   Ismail-Beigi F, 2010, LANCET, V376, P419, DOI 10.1016/S0140-6736(10)60576-4
   Jordan J, 2019, J HYPERTENS, V37, P1541, DOI 10.1097/HJH.0000000000002078
   Lalieu RC, 2020, WOUND REPAIR REGEN, V28, P266, DOI 10.1111/wrr.12776
   Lambert AP, 2003, DIABETES CARE, V26, P333, DOI 10.2337/diacare.26.2.333
   Löndahl M, 2010, DIABETES CARE, V33, P998, DOI 10.2337/dc09-1754
   Lu YH, 2020, FRONT PUBLIC HEALTH, V8, DOI 10.3389/fpubh.2020.534372
   Maganti K, 2003, AM J GASTROENTEROL, V98, P259
   Martin CL, 2014, DIABETES CARE, V37, P31, DOI 10.2337/dc13-2114
   Maturi RK, 2021, JAMA OPHTHALMOL, V139, P701, DOI 10.1001/jamaophthalmol.2021.0606
   Mazhar K, 2011, OPHTHALMOLOGY, V118, P649, DOI 10.1016/j.ophtha.2010.08.003
   McCallum RW, 2010, CLIN GASTROENTEROL H, V8, P947, DOI 10.1016/j.cgh.2010.05.020
   Mitchell P, 2011, OPHTHALMOLOGY, V118, P615, DOI 10.1016/j.ophtha.2011.01.031
   Nathan DM, 2017, NEW ENGL J MED, V376, P1507, DOI 10.1056/NEJMoa1612836
   Niederauer MQ, 2018, J WOUND CARE, V27, pS30, DOI 10.12968/jowc.2018.27.Sup9.S30
   Olausson EA, 2014, AM J GASTROENTEROL, V109, P375, DOI 10.1038/ajg.2013.453
   Parkman HP, 2011, GASTROENTEROLOGY, V141, P486, DOI 10.1053/j.gastro.2011.04.045
   Parrish CR., 2007, Diabetes Spectr, V20, P231, DOI DOI 10.2337/DIASPECT.20.4.231
   Peters A, 2017, DIABETOLOGIA, V60, P980, DOI 10.1007/s00125-017-4253-z
   Pham H, 2000, DIABETES CARE, V23, P606, DOI 10.2337/diacare.23.5.606
   Pop-Busui R, 2022, Diagnosis and treatment of painful diabetic peripheral neuropathy
   Pop-Busui R, 2017, DIABETES CARE, V40, P136, DOI 10.2337/dc16-2042
   Pop-Busui R, 2013, DIABETES CARE, V36, P3208, DOI 10.2337/dc13-0012
   Pop-Busui R, 2013, J AM COLL CARDIOL, V61, P447, DOI 10.1016/j.jacc.2012.10.028
   Pop-Busui R, 2010, DIABETES CARE, V33, P1578, DOI 10.2337/dc10-0125
   Pop-Busui R, 2009, CIRCULATION, V119, P2886, DOI 10.1161/CIRCULATIONAHA.108.837369
   Price R, 2022, NEUROLOGY, V98, P31, DOI 10.1212/WNL.0000000000013038
   Reaney M, 2022, APPL PSYCHOL-HLTH WE, V14, P465, DOI 10.1111/aphw.12314
   Reiber GE, 1999, DIABETES CARE, V22, P157, DOI 10.2337/diacare.22.1.157
   Rogers LC, 2011, DIABETES CARE, V34, P2123, DOI 10.2337/dc11-0844
   Sadosky A, 2013, DIABET METAB SYND OB, V6, P79, DOI 10.2147/DMSO.S37415
   Santema KTB, 2018, DIABETES CARE, V41, P112, DOI 10.2337/dc17-0654
   Schaper NC, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3266
   Serena TE, 2021, J WOUND CARE, V30, pS7, DOI 10.12968/jowc.2021.30.Sup5.S7
   Sethi A., 2022, Health Sci Rev, V3, P100028
   SHAMOON H, 1993, NEW ENGL J MED, V329, P977, DOI 10.1056/NEJM199307293290502
   Sheehan P, 2003, DIABETES CARE, V26, P1879, DOI 10.2337/diacare.26.6.1879
   Shi R, 2018, INT J OPHTHALMOL-CHI, V11, P287, DOI 10.18240/ijo.2018.02.18
   Silva PS, 2016, OPHTHALMOLOGY, V123, P1360, DOI 10.1016/j.ophtha.2016.01.043
   Sim Dawn A, 2016, J Diabetes Sci Technol, V10, P308, DOI [10.1177/1932296816629983, 10.1177/1932296816629983]
   Sivaprasad S, 2017, LANCET, V389, P2193, DOI 10.1016/S0140-6736(17)31193-5
   Smith AG, 2014, J DIABETES COMPLICAT, V28, P511, DOI 10.1016/j.jdiacomp.2014.02.013
   Solomon SD, 2017, DIABETES CARE, V40, P412, DOI 10.2337/dc16-2641
   Stratton IM, 2001, DIABETOLOGIA, V44, P156, DOI 10.1007/s001250051594
   Sugumar A, 2008, CLIN GASTROENTEROL H, V6, P726, DOI 10.1016/j.cgh.2008.02.065
   Sun XK, 2022, INT WOUND J, V19, P2200, DOI 10.1111/iwj.13830
   Tang YL, 2021, DIABETES CARE, V44, P164, DOI 10.2337/dc20-1842
   Tesfaye S, 2022, LANCET, V400, P680, DOI 10.1016/S0140-6736(22)01472-6
   Turner RC, 1998, LANCET, V352, P837, DOI 10.1016/s0140-6736(98)07019-6
   U.S. Food and Drug Administration, 2022, K221183 - 510(k) Premarket notification
   U.S. Food and Drug Administration, 2020, K200667 - 510(k) Premarket notification
   Umpierrez G., 2014, Therapy for diabetes mellitus and related disorders
   van Netten JJ, 2016, DIABETES-METAB RES, V32, P84, DOI 10.1002/dmrr.2701
   Waldfogel JM, 2017, NEUROLOGY, V88, P1958, DOI 10.1212/WNL.0000000000003882
   Walton DV, 2021, J WOUND CARE, V30, P598, DOI 10.12968/jowc.2021.30.8.598
   Walton OB, 2016, JAMA OPHTHALMOL, V134, P204, DOI 10.1001/jamaophthalmol.2015.5083
   Wells JA, 2015, NEW ENGL J MED, V372, P1193, DOI 10.1056/NEJMoa1414264
   Widyaputri F, 2022, JAMA OPHTHALMOL, V140, P486, DOI 10.1001/jamaophthalmol.2022.0050
   Yau JWY, 2012, DIABETES CARE, V35, P556, DOI 10.2337/dc11-1909
   Yuncken J, 2018, ENDOCRINE, V62, P250, DOI 10.1007/s12020-018-1714-1
NR 112
TC 164
Z9 189
U1 5
U2 32
PU AMER DIABETES ASSOC
PI ALEXANDRIA
PA 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA
SN 0149-5992
EI 1935-5548
J9 DIABETES CARE
JI Diabetes Care
PD JAN
PY 2024
VL 47
SU 1
BP S231
EP S243
DI 10.2337/dc24-S012
PG 13
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA OL9C3
UT WOS:001207535600001
PM 38078577
OA Green Submitted, Bronze
HC Y
HP N
DA 2026-07-24
ER

PT J
AU Gage, MJ
   Yoon, RS
   Gaines, RJ
   Dunbar, RP
   Egol, KA
   Liporace, FA
AF Gage, Mark J.
   Yoon, Richard S.
   Gaines, Robert J.
   Dunbar, Robert P.
   Egol, Kenneth A.
   Liporace, Frank A.
TI Dead Space Management After Orthopaedic Trauma: Tips, Tricks, and
   Pitfalls
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Review
DE dead space; infection; trauma; open wound; high energy; open fracture;
   limb salvage
ID PRESSURE WOUND THERAPY; VACUUM-ASSISTED CLOSURE; LOCAL
   ANTIBIOTIC-THERAPY; ACRYLIC BONE-CEMENT; CLOSED INCISION MANAGEMENT;
   TOTAL KNEE ARTHROPLASTY; INFECTED TOTAL HIP; OPEN FRACTURES;
   LOWER-EXTREMITY; INDUCED MEMBRANES
AB Dead space is defined as the residual tissue void after tissue loss. This may occur due to tissue necrosis after high-energy trauma, infection, or surgical debridement of nonviable tissue. This review provides an update on the state of the art and recent advances in the management of osseous and soft tissue defects. Specifically, our focus will be on the initial dead space assessment, provisional management of osseous and soft tissue defects, techniques for definitive reconstruction, and dead space management in the setting of infection.Level of Evidence:Therapeutic Level V. See Instructions for Authors for a complete description of levels of evidence.
C1 [Gage, Mark J.; Yoon, Richard S.; Egol, Kenneth A.; Liporace, Frank A.] NYU, Hosp Joint Dis, Dept Orthopaed Surg, Div Orthopaed Trauma, 301 E 17th St,Suite 1402, New York, NY 10003 USA.
   [Gaines, Robert J.] Covenant Hlth Syst, Dept Orthopaed Surg, Div Orthopaed Trauma, Lubbock, TX USA.
   [Dunbar, Robert P.] Univ Washington, Harborview Med Ctr, Dept Orthopaed Surg, Div Orthopaed Trauma, 325 9Th Ave, Seattle, WA 98104 USA.
C3 New York University; NYU Langone Medical Center; Hospital for Joint
   Disease NYULMC; University of Washington; University of Washington
   Seattle; Harborview Medical Center
RP Liporace, FA (通讯作者)，NYU, Hosp Joint Dis, Dept Orthopaed Surg, Div Orthopaed Trauma, 301 E 17th St,Suite 1402, New York, NY 10003 USA.
EM liporace33@gmail.com
RI Yoon, Richard/D-2522-2009
OI Yoon, Richard/0000-0001-5240-6633; Gage, Mark/0000-0002-7410-7850
CR Aho OM, 2013, J BONE JOINT SURG AM, V95A, P597, DOI 10.2106/JBJS.L.00310
   Akhtar S, 2006, J PLAST RECONSTR AES, V59, P839, DOI 10.1016/j.bjps.2005.12.009
   Anagnostakos K, 2009, ACTA ORTHOP, V80, P193, DOI 10.3109/17453670902884700
   Beltran MJ, 2014, J ORTHOP TRAUMA, V28, pE15, DOI 10.1097/BOT.0b013e3182940b65
   Beltran Michael J, 2010, J Surg Orthop Adv, V19, P23
   Bhandari M, 2001, J BONE JOINT SURG BR, V83B, P62, DOI 10.1302/0301-620X.83B1.10986
   Buttaro MA, 2005, ACTA ORTHOP, V76, P336, DOI 10.1080/00016470510030797
   Buttaro MA, 2005, J BONE JOINT SURG BR, V87B, P314, DOI 10.1302/0301-620X.87B3.14788
   Buttaro MA, 2010, HIP INT, V20, P535, DOI 10.1177/112070001002000419
   Chen Shao-zong, 2005, Zhonghua Zheng Xing Wai Ke Za Zhi, V21, P197
   Christensen TJ, 2013, J ORTHOP TRAUMA, V27, P107, DOI 10.1097/BOT.0b013e318251219c
   Colen L, 2006, PLAST RECONSTR SURG, V117, P1323, DOI 10.1097/01.prs.0000204960.48050.e5
   Court-Brown CM, 2012, INJURY, V43, P891, DOI 10.1016/j.injury.2011.12.007
   Cui QJ, 2007, J BONE JOINT SURG AM, V89A, P871, DOI 10.2106/JBJS.E.01070
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   DeLong WG, 1999, J TRAUMA, V46, P1049, DOI 10.1097/00005373-199906000-00012
   Dimitriou R, 2011, INJURY, V42, pS3, DOI 10.1016/j.injury.2011.06.015
   Forsberg JA, 2011, J AM ACAD ORTHOP SUR, V19, pS8, DOI 10.5435/00124635-201102001-00003
   Geiger MH, 2001, CLIN ORTHOP RELAT R, P258
   Geurts J, 2011, INJURY, V42, pS82, DOI 10.1016/j.injury.2011.06.189
   Girard PJ, 2013, J ORTHOP TRAUMA, V27, pe220, DOI 10.1097/BOT.0b013e31827069b9
   GREEN SA, 1994, CLIN ORTHOP RELAT R, P111
   Greene N, 1998, Am J Orthop (Belle Mead NJ), V27, P201
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Henrich D, 2010, INJURY, V41, pS62, DOI 10.1016/S0020-1383(10)70012-7
   HENRY SL, 1990, J TRAUMA, V30, P1231, DOI 10.1097/00005373-199010000-00007
   HENRY SL, 1993, CLIN ORTHOP RELAT R, P54
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   Hofmann AA, 2005, J ARTHROPLASTY, V20, P874, DOI 10.1016/j.arth.2004.12.055
   Hofmann AA, 2005, CLIN ORTHOP RELAT R, P125, DOI 10.1097/01.blo.0000149241.77924.01
   Hohmann E, 2007, ARCH ORTHOP TRAUM SU, V127, P131, DOI 10.1007/s00402-006-0222-6
   Hsieh PH, 2004, J TRAUMA, V56, P1247, DOI 10.1097/01.TA.0000130757.53559.BF
   Jaeblon T, 2010, J AM ACAD ORTHOP SUR, V18, P297, DOI 10.5435/00124635-201005000-00006
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Klekamp J, 1999, J ARTHROPLASTY, V14, P339, DOI 10.1016/S0883-5403(99)90061-X
   KUECHLE DK, 1991, CLIN ORTHOP RELAT R, P302
   Kuehn KD, 2005, ORTHOP CLIN N AM, V36, P29, DOI 10.1016/j.ocl.2004.06.011
   Labler L, 2009, J TRAUMA, V66, P749, DOI 10.1097/TA.0b013e318171971a
   Lee Hyun-Joo, 2009, J Orthop Surg Res, V4, P14, DOI 10.1186/1749-799X-4-14
   Lenarz CJ, 2010, J BONE JOINT SURG AM, V92A, P1921, DOI 10.2106/JBJS.I.00547
   Liporace FA, 2012, J ORTHOP TRAUMA, V26, pE18, DOI 10.1097/BOT.0b013e318216dd60
   Lowe JA, 2010, J ORTHOP TRAUMA, V24, P46, DOI 10.1097/BOT.0b013e31819c0ccb
   Malmsjo Malin, 2012, Eplasty, V12, pe5
   Masquelet A, 2014, INSTR COURS LECT 201, P17
   Masquelet A C, 2000, Ann Chir Plast Esthet, V45, P346
   Masquelet AC, 2003, LANGENBECK ARCH SURG, V388, P344, DOI 10.1007/s00423-003-0379-1
   Masquelet AC, 2010, ORTHOP CLIN N AM, V41, P27, DOI 10.1016/j.ocl.2009.07.011
   Masri BA, 1998, J ARTHROPLASTY, V13, P331, DOI 10.1016/S0883-5403(98)90179-6
   McNulty AK, 2007, WOUND REPAIR REGEN, V15, P838, DOI 10.1111/j.1524-475X.2007.00287.x
   Meeker J, 2011, J ORTHOP TRAUMA, V25, P756, DOI 10.1097/BOT.0b013e318211363a
   Mekhail AO, 2004, J TRAUMA, V56, P368, DOI 10.1097/01.TA.0000057234.48501.30
   Melvin JS, 2010, J AM ACAD ORTHOP SUR, V18, P10
   Morimoto S, 2003, J ARTHROPLASTY, V18, P216, DOI 10.1054/arth.2003.50037
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Moucha CS, 2011, J BONE JOINT SURG AM, V93A, P398
   Namdari Surena, 2011, J Orthop Trauma, V25, P140, DOI 10.1097/BOT.0b013e3181e3dff1
   Neut D, 2003, ACTA ORTHOP SCAND, V74, P670, DOI 10.1080/00016470310018180
   Nho SJ, 2006, J ORTHOP TRAUMA, V20, P419, DOI 10.1097/00005131-200607000-00010
   OSTERMANN PAW, 1995, J BONE JOINT SURG BR, V77B, P93, DOI 10.1302/0301-620X.77B1.7822405
   OSTERMANN PAW, 1993, CLIN ORTHOP RELAT R, P102
   Parrett BM, 2006, PLAST RECONSTR SURG, V117, P1315, DOI 10.1097/01.prs.0000204959.18136.36
   Pelham F R, 2006, J Wound Care, V15, P111
   Pelissier P, 2004, J ORTHOP RES, V22, P73, DOI 10.1016/S0736-0266(03)00165-7
   Pelissier P, 2002, BRIT J PLAST SURG, V55, P596, DOI 10.1054/bjps.2002.3936
   Penner MJ, 1996, J ARTHROPLASTY, V11, P939, DOI 10.1016/S0883-5403(96)80135-5
   Polyzois D, 1997, ACTA ORTHOP SCAND, V68, P84, DOI 10.1080/17453674.1997.11744753
   Prasarn Mark L, 2009, Am J Orthop (Belle Mead NJ), V38, P559
   Reddix Robert N Jr, 2010, J Surg Orthop Adv, V19, P91
   Ristiniemi J, 2007, ACTA ORTHOP, V78, P520, DOI 10.1080/17453670710014176
   SANDERS R, 1993, J BONE JOINT SURG AM, V75A, P778, DOI 10.2106/00004623-199305000-00020
   Song HR, 2003, J ORTHOP TRAUMA, V17, P203, DOI 10.1097/00005131-200303000-00009
   Springer BD, 2004, CLIN ORTHOP RELAT R, P47, DOI 10.1097/01.blo.0000144476.43661.10
   Stafford PR, 2010, INJURY, V41, pS72, DOI 10.1016/S0020-1383(10)70014-0
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Sun XT, 2011, J BONE JOINT SURG BR, V93B, P782, DOI 10.1302/0301-620X.93B6.25521
   Tarkin IS, 2008, J ORTHOP TRAUMA, V22, pS146, DOI 10.1097/BOT.0b013e318188e2bc
   Taylor BC, 2012, J AM ACAD ORTHOP SUR, V20, P142, DOI 10.5435/JAAOS-20-03-142
   Thonse R, 2007, J ORTHOP TRAUMA, V21, P258, DOI 10.1097/BOT.0b013e31803ea9e6
   Timmers MS, 2005, ANN PLAS SURG, V55, P665, DOI 10.1097/01.sap.0000187182.90907.3d
   WATSON JT, 2006, J AM ACAD ORTHOP SUR, V14, P168
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Winkler H, 2008, J BONE JOINT SURG BR, V90B, P1580, DOI 10.1302/0301-620X.90B12.20742
   Winkler H, 2000, J ANTIMICROB CHEMOTH, V46, P423, DOI 10.1093/jac/46.3.423
   Yang Charlie C, 2006, J Surg Orthop Adv, V15, P19
   Zalavras CG, 2004, CLIN ORTHOP RELAT R, P86, DOI 10.1097/01.blo.0000143571.18892.8d
   Zalavras CG, 2004, CLIN ORTHOP RELAT R, P57, DOI 10.1097/01.blo.0000143557.18601.7d
   Zannis J, 2009, ANN PLAS SURG, V62, P407, DOI 10.1097/SAP.0b013e3181881b29
NR 87
TC 12
Z9 15
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD FEB
PY 2016
VL 30
IS 2
BP 64
EP 70
DI 10.1097/BOT.0000000000000454
PG 7
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA DC6AS
UT WOS:000369302600002
PM 26429404
DA 2026-07-24
ER

PT J
AU Hagiya, H
   Matsumoto, M
   Yamasawa, T
   Haruki, Y
   Otsuka, F
AF Hagiya, Hideharu
   Matsumoto, Mitsuaki
   Yamasawa, Takahiko
   Haruki, Yuto
   Otsuka, Fumio
TI A Case of Vascular Graft Infection Caused by Staphylococcus
   lugdunensis after Femoropopliteal Bypass Operation
SO ACTA MEDICA OKAYAMA
LA English
DT Article
DE coagulase-negative Staphylococcus (CNS); femoropopliteal (FP) bypass;
   Staphylococcus lugdunensis; vacuum-assisted closure (VAC) therapy;
   vascular graft infection (VGI)
ID CLINICAL-PRACTICE GUIDELINES; CHLORHEXIDINE; ENDOCARDITIS; FREQUENCY;
   TRIAL
AB A 79-year-old man who had undergone a right femoropopliteal (FP) bypass operation 6 weeks previously was diagnosed with vascular graft infection caused by Staphylococcus lugdunensis. Another FP bypass operation was performed, with long-term administration of antibiotics, and the patient eventually recovered well without any recurrences for over 2 years. Although S. lugdunens is classified as coagulase-negative Staphylococcus, its pathogenicity has been reported to be equal to that of S. aureus. Based on the literature review, the organism characteristically colonizes the inguinal area of human skin; thus, operations such as FP bypass grafting may place patients at a relatively high risk for infection by S. lugdunensis, a potentially high-pathogenicity organism.
C1 [Hagiya, Hideharu; Otsuka, Fumio] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Gen Med, Okayama 7008558, Japan.
   [Hagiya, Hideharu] Tsuyama Cent Hosp, Emergency Unit, Tsuyama, Okayama 7080841, Japan.
   [Hagiya, Hideharu] Tsuyama Cent Hosp, Crit Care Ctr, Tsuyama, Okayama 7080841, Japan.
   [Matsumoto, Mitsuaki; Yamasawa, Takahiko] Tsuyama Cent Hosp, Dept Cardiac Surg, Tsuyama, Okayama 7080841, Japan.
   [Haruki, Yuto] Tsuyama Cent Hosp, Dept Pharm, Tsuyama, Okayama 7080841, Japan.
C3 Okayama University
RP Hagiya, H (通讯作者)，Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Gen Med, Okayama 7008558, Japan.
EM e_dai_for_all@hotmail.com
CR Anderson DJ, Infect
   Braithwaite BD, 1998, BRIT J SURG, V85, P1378
   Bratzler DW, 2013, SURG INFECT, V14, P73, DOI 10.1089/sur.2013.9999
   Cevasco M, 2012, J CARDIAC SURG, V27, P299, DOI 10.1111/j.1540-8191.2011.01267.x
   Choi SH, 2010, J CLIN MICROBIOL, V48, P3346, DOI 10.1128/JCM.00609-10
   Climo MW, 2013, NEW ENGL J MED, V368, P533, DOI 10.1056/NEJMoa1113849
   Climo MW, 2009, CRIT CARE MED, V37, P1858, DOI 10.1097/CCM.0b013e31819ffe6d
   D'Addato M, 1996, Cardiovasc Surg, V4, P200, DOI 10.1016/0967-2109(96)82315-5
   Darouiche RO, 2010, NEW ENGL J MED, V362, P18, DOI 10.1056/NEJMoa0810988
   Earnshaw JJ, 2000, BRIT J SURG, V87, P758, DOI 10.1046/j.1365-2168.2000.01490.x
   Fadel HJ, 2011, J CLIN MICROBIOL, V49, P1697, DOI 10.1128/JCM.02058-10
   Frank KL, 2008, CLIN MICROBIOL REV, V21, P111, DOI 10.1128/CMR.00036-07
   Hasse B, 2013, SWISS MED WKLY, V143, DOI 10.4414/smw.2013.13754
   HERCHLINE TE, 1991, J CLIN MICROBIOL, V29, P419, DOI 10.1128/JCM.29.3.419-421.1991
   Kleiner E, 2010, CLIN INFECT DIS, V51, P801, DOI 10.1086/656280
   Klotchko A, 2011, SOUTH MED J, V104, P509, DOI 10.1097/SMJ.0b013e31821e91b1
   Liang M, 2012, NEW ZEAL MED J, V125, P51
   Liu PY, 2010, J MICROBIOL IMMUNOL, V43, P478, DOI 10.1016/S1684-1182(10)60074-6
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Matthews PC, 2008, INT J CARDIOL, V130, P87, DOI 10.1016/j.ijcard.2007.06.068
   Matthews PC, 2011, J CLIN MICROBIOL, V49, P2740, DOI 10.1128/JCM.00722-11
   Mermel LA, 2009, CLIN INFECT DIS, V49, P1, DOI 10.1086/599376
   Nagpal Avish, 2011, Curr Infect Dis Rep, V13, P317, DOI 10.1007/s11908-011-0191-y
   Papapetropoulos N, 2013, INFECTION, V41, P525, DOI 10.1007/s15010-012-0381-z
   Rogers KL, 2009, INFECT DIS CLIN N AM, V23, P73, DOI 10.1016/j.idc.2008.10.001
   ROTTER ML, 1988, J HOSP INFECT, V11, P310, DOI 10.1016/0195-6701(88)90083-7
   Saleem BR, 2010, AM J SURG, V200, P47, DOI 10.1016/j.amjsurg.2009.05.018
   Shah NB, 2010, J CLIN MICROBIOL, V48, P1600, DOI 10.1128/JCM.01769-09
   Takahashi N, 2009, INT J CARDIOL, V137, pE15, DOI 10.1016/j.ijcard.2008.05.041
   Tsao YT, 2012, INT J INFECT DIS, V16, pE464, DOI 10.1016/j.ijid.2012.02.010
   van der Mee-Marquet N, 2003, J CLIN MICROBIOL, V41, P1404, DOI 10.1128/JCM.41.4.1404-1409.2003
   Zinkernagel AS, 2008, INFECTION, V36, P314, DOI 10.1007/s15010-008-7287-9
NR 32
TC 0
Z9 3
U1 0
U2 4
PU OKAYAMA UNIV MED SCHOOL
PI OKAYAMA
PA EDITORIAL OFFICE, ACTA MEDICA OKAYAMA OKAYAMA UNIVERSITY MEDICAL SCHOOL
   2-5-1 SHIKATA-CHO, KITA-KU, OKAYAMA, 700-8558, JAPAN
SN 0386-300X
J9 ACTA MED OKAYAMA
JI Acta Med. Okayama
PD JUN
PY 2014
VL 68
IS 3
BP 171
EP 175
PG 5
WC Medicine, Research & Experimental
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine
GA AJ4OL
UT WOS:000337655600007
PM 24942796
DA 2026-07-24
ER

PT J
AU Alavi, A
   Kirsner, RS
AF Alavi, Afsaneh
   Kirsner, Robert S.
TI Local wound care and topical management of hidradenitis suppurativa
SO JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
LA English
DT Article
DE clindamycin; hidradenitis suppurativa; NPWT; resorcinol; retinoid;
   topical treatments
ID NEGATIVE-PRESSURE DRESSINGS; VACUUM-ASSISTED CLOSURE; THICKNESS
   SKIN-GRAFTS; CLINDAMYCIN
AB Hidradenitis suppurativa (HS) is a chronic, recurrent, debilitating disease predominantly involving apocrine gland-bearing skin. The folliculoinfundibular dysfunction and an aberrant cutaneous immune response to commensal bacteria are recognized as potential contributors. Topical antibiotics, such as clindamycin, and keratolytic agents have been used in the management of early stages of HS. Proper wound care is a key part of management, particularly in patients with advanced HS. The evidence for the optimal topical therapy or optimal local wound care is limited. As such, a multidisciplinary approach is necessary to address all aspects of HS, including topical therapy, systemic therapy, and proper wound care. The focus of this paper is to review the evidence for the topical management and local wound care strategies in patients with HS.
C1 [Alavi, Afsaneh] Univ Toronto, Dept Med Dermatol, Toronto, ON M5S 1B2, Canada.
   [Kirsner, Robert S.] Univ Miami, Dept Dermatol, Coral Gables, FL 33124 USA.
   [Kirsner, Robert S.] Univ Miami, Dept Cutaneous Surg, Coral Gables, FL 33124 USA.
C3 University of Toronto; University of Miami; University of Miami
RP Alavi, A (通讯作者)，Univ Toronto, Womens Coll Hosp, Wound Care Ctr, Dept Med Dermatol, Main Bldg,76 Grenville St,10th Fl, Toronto, ON M5S 1B2, Canada.
EM afsaneh.alavi@utoronto.ca
OI alavi, afsaneh/0000-0003-1171-4917
FU AbbVie
FX Dr Alavi is an advisor, consultant, and speaker for AbbVie and Janssen.
   She is an investigator for AbbVie and Novartis and received an
   unrestricted educational grant from AbbVie. Dr Kirsner declared no
   conflicts of interest.
CR Alavi A, 2015, AM J CLIN DERMATOL, V16, P61, DOI 10.1007/s40257-014-0105-5
   Blackburn JH, 1998, ANN PLAS SURG, V40, P453, DOI 10.1097/00000637-199805000-00001
   Boer J, 2010, CLIN EXP DERMATOL, V35, P36, DOI 10.1111/j.1365-2230.2009.03377.x
   Chen E, 2011, ANN PLAS SURG, V67, P397, DOI 10.1097/SAP.0b013e3181f77bd6
   Chen YE, 2014, PLAST RECONSTR SURG, V133, p370E, DOI 10.1097/PRS.0000000000000080
   CLEMMENSEN OJ, 1983, INT J DERMATOL, V22, P325, DOI 10.1111/j.1365-4362.1983.tb02150.x
   Elwood ET, 2001, ANN PLAS SURG, V46, P49, DOI 10.1097/00000637-200101000-00010
   Hynes PJ, 2002, BRIT J PLAST SURG, V55, P507, DOI 10.1054/bjps.2002.3899
   Jemec GBE, 2012, BRIT J DERMATOL, V166, P237, DOI 10.1111/j.1365-2133.2012.10802.x
   Jemec GBE, 1998, J AM ACAD DERMATOL, V39, P971, DOI 10.1016/S0190-9622(98)70272-5
   Jemec GBE, 2012, NEW ENGL J MED, V366, P158, DOI 10.1056/NEJMcp1014163
   Karpouzis A, 2003, EUR J DERMATOL, V13, P192
   Lapins J, 1999, BRIT J DERMATOL, V140, P90
   Ludolph I, 2014, INT WOUND J, V21
   McPhee M, 2015, BR J DERMATOL
   MORGAN WP, 1980, BRIT J SURG, V67, P277, DOI 10.1002/bjs.1800670416
   Nicoli F, 2015, INT WOUND J, V12, P338, DOI 10.1111/iwj.12117
   Tang JB, 2015, INT WOUND J, V12, P334, DOI 10.1111/iwj.12116
NR 18
TC 31
Z9 38
U1 1
U2 6
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0190-9622
J9 J AM ACAD DERMATOL
JI J. Am. Acad. Dermatol.
PD NOV
PY 2015
VL 73
IS 5
SU 1
BP S55
EP S61
DI 10.1016/j.jaad.2015.07.048
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA CU4IE
UT WOS:000363490300013
PM 26470618
DA 2026-07-24
ER

PT J
AU Karl, T
   Modic, PK
   Voss, EU
AF Karl, T
   Modic, PK
   Voss, EU
TI Indications and results of VAC® therapy treatments in
   vascular surgery state of the art in the treatment of chronic wounds
SO ZENTRALBLATT FUR CHIRURGIE
LA German
DT Article; Proceedings Paper
CT Three Country Congress on VAC Therapy for Outpatients as well as
   In-Hospital Patients
CY MAY 21-22, 2003
CL Mainz, GERMANY
DE VAC((R)) therapy; chronic wounds; varicose ulcer; diabetic gangrene;
   vascular graft infections
AB Almost 10% of the population are concerned in the course of her life by chronic wounds, mortality resulting from this amount to 2.5% [15, 25, 34]. The Vacuum assisted closure (V.A.C.(R)) therapy represents a modern procedure for the treatment of chronic wounds. Also in some first appearing offering no prospects cases hereby the Majoramputation can be prevented and the majority of chronic therapy-resistant wounds can be healed. Due to first experiences with the V.A.C.(R) therapy with the treatment of infected vascular grafts in the stage II and III after Szilagyi it also offers a success - promising option to concerne the extremity and the life of the patient and to receive but also the infected graft in situ.
C1 Stadt Kliniken Karlsruhe, Chirurg Klin, D-76133 Karlsruhe, Germany.
   Univ Freiburg, Akad Lehrkrankenhaus, D-7800 Freiburg, Germany.
C3 Municipal Hospital Karlsruhe; University of Freiburg
RP Karl, T (通讯作者)，Stadt Kliniken Karlsruhe, Chirurg Klin, Moltkestr 90, D-76133 Karlsruhe, Germany.
EM dr.t.karl@web.de
CR Armstrong David G, 2002, Ostomy Wound Manage, V48, P64
   Banwell P E, 1999, J Wound Care, V8, P79
   Clare MP, 2002, FOOT ANKLE INT, V23, P896, DOI 10.1177/107110070202301002
   CLEMENT H, 2003, EUR SURG ACA S, V35, P7
   Fay M F, 1987, AORN J, V46, P442, DOI 10.1016/S0001-2092(07)66456-4
   FIEBIGER M, 2003, EUR SURG ACA S, V35, P32
   Fleischmann W, 1995, Eur J Orthop Surg Traumatol, V5, P37, DOI 10.1007/BF02716212
   Fleischmann W, 1998, UNFALLCHIRURG, V101, P649, DOI 10.1007/s001130050318
   FLEISCHMANN W, 1995, LANGENBECKS ARCH C S, V1, P256
   HACH W, 1985, MED WELT, V36, P1616
   HAGER D, 2003, EUR SURG ACA S, V35, P8
   Hauer G, 1996, CHIRURG, V67, P505
   HELLER G, 2003, EUR SURG ACA S, V35, P34
   HEPP W, 2001, GEFASSCHIRUGIE, P669
   KEHR HH, 1997, AKUTE CHRONISCHE WUN, P55
   KOHLER U, 1998, GEFASSCHIRURGIE, V3, P82
   Labler L, 2003, EUR SURG ACA S, V35, P10
   LILGENAU N, 2003, EUR SURG ACA S, V35, P28
   MOEHRLEN U, 2003, EUR SURG ACA S, V35, P17
   MOIDL R, 2003, EUR SURG ACA S, V35, P22
   Molnar JA, 2000, PLAST RECONSTR SURG, V105, P174, DOI 10.1097/00006534-200001000-00030
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   MORYKWAS MJ, 1998, ACTA CHIR, V150, P3
   PELKA RB, UNPUB EXPERTISE KOST
   Philippidis TP, 1999, COMPOS STRUCT, V45, P41, DOI 10.1016/S0263-8223(99)00012-4
   Rejzek A, 1998, ACTA CHIR AUST     S, V150, P12
   SCHERER LA, 2003, ARCH SURG-CHICAGO, V137, P930
   SCHLATTER M, 2003, EUR SURG ACA S, V35, P15
   VOLLMAR J, 1996, REKONSTRUKTIVE CHIRU, P413
   WALDENBERGER FR, 2003, EUR SURG ACA S, V35, P20
   Walgenbach KJ, 2000, Z FLUGWISS WELTRAUM, V13, P9
   *WEINB GROUP, 1999, TECHN ASS VAC HOM TR
   WINKLER M, 2004, Z FLUGWISS WELTRAUM, V9, P24
   ZIEGLER UE, 2003, EUR SURG ACA S, V35, P18
   2002, MILLIMAN STUDIE US E
NR 35
TC 9
Z9 17
U1 0
U2 0
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 0044-409X
EI 1438-9592
J9 ZBL CHIR
JI Zent.bl. Chir.
PD MAY
PY 2004
VL 129
SU 1
BP S74
EP S79
DI 10.1055/s-2004-822609
PG 6
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Surgery
GA 826GF
UT WOS:000221816600024
PM 15168294
DA 2026-07-24
ER

PT J
AU Abu-Omar, Y
   Kocher, GJ
   Bosco, P
   Barbero, C
   Waller, D
   Gudbjartsson, T
   Sousa-Uva, M
   Licht, PB
   Dunning, J
   Schmid, RA
   Cardillo, G
AF Abu-Omar, Yasir
   Kocher, Gregor J.
   Bosco, Paolo
   Barbero, Cristina
   Waller, David
   Gudbjartsson, Tomas
   Sousa-Uva, Miguel
   Licht, Peter B.
   Dunning, Joel
   Schmid, Ralph A.
   Cardillo, Giuseppe
TI European Association for Cardio-Thoracic Surgery expert consensus
   statement on the prevention and management of mediastinitis
SO EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
LA English
DT Article
DE Mediastinitis; Cardiac surgery; General thoracic surgery; Treatment;
   Prevention; Guideline
ID STERNAL WOUND INFECTIONS; SURGICAL-SITE INFECTION; DESCENDING
   NECROTIZING MEDIASTINITIS; STAPHYLOCOCCUS-AUREUS INFECTIONS;
   VACUUM-ASSISTED CLOSURE; BYPASS GRAFT-SURGERY; GENTAMICIN-COLLAGEN
   SPONGE; RISK-FACTOR-ANALYSIS; CARDIAC-SURGERY; POSTSTERNOTOMY
   MEDIASTINITIS
AB Mediastinitis continues to be an important and life-threatening complication after median sternotomy despite advances in prevention and treatment strategies, with an incidence of 0.25-5%. It can also occur as extension of infection from adjacent structures such as the oesophagus, airways and lungs, or as descending necrotizing infection from the head and neck. In addition, there is a chronic form of 'chronic fibrosing mediastinitis' usually caused by granulomatous infections. In this expert consensus, the evidence for strategies for treatment and prevention of mediatinitis is reviewed in detail aiming at reducing the incidence and optimizing the management of this serious condition.
C1 [Abu-Omar, Yasir; Bosco, Paolo; Schmid, Ralph A.] Papworth Hosp NHS Fdn Trust, Dept Cardiothorac Surg, Cambridge CB23 3RE, England.
   [Kocher, Gregor J.] Inselspital Bern, Univ Hosp Bern, Div Gen Thorac Surg, Bern, Switzerland.
   [Barbero, Cristina] Univ Turin, Dept Cardiovasc & Thorac Surg, Turin, Italy.
   [Barbero, Cristina] San Giovanni Battista Hosp, Citta Salute & Sci, Turin, Italy.
   [Waller, David] Glenfield Hosp, Dept Thorac Surg, Leicester, Leics, England.
   [Gudbjartsson, Tomas] Univ Iceland, Landspitali Univ Hosp, Dept Cardiothorac Surg, Reykjavik, Iceland.
   [Gudbjartsson, Tomas] Univ Iceland, Fac Med, Reykjavik, Iceland.
   [Sousa-Uva, Miguel] Hosp Cruz Vermelha, Unit Cardiac Surg, Lisbon, Portugal.
   [Licht, Peter B.] Odense Univ Hosp, Dept Cardiothorac Surg, Clin Guidelines Comm, Odense, Denmark.
   [Dunning, Joel] James Cook Univ Hosp, Dept Cardiothorac Surg, Middlesbrough, Cleveland, England.
   [Cardillo, Giuseppe] Lazzaro Spallanzani Hosp, Unit Thorac Surg, Azienda Osped S Camillo Forlanini, EACTS Thorac Domain, Rome, Italy.
C3 Papworth Hospital; University of Bern; University Hospital of Bern;
   University of Turin; A.O.U. Citta della Salute e della Scienza di
   Torino; AOU San Giovanni Battista-Molinette; University Hospitals of
   Leicester NHS Trust; University of Leicester; Glenfield Hospital;
   Landspitali National University Hospital; University of Iceland;
   University of Iceland; University of Southern Denmark; Odense University
   Hospital; James Cook University Hospital; Azienda Ospedaliera San
   Camillo-Forlanini; IRCCS Lazzaro Spallanzani
RP Abu-Omar, Y (通讯作者)，Papworth Hosp NHS Fdn Trust, Dept Cardiothorac Surg, Cambridge CB23 3RE, England.
EM y.abuomar@nhs.net
RI Kocher, Gregor Jan/GQZ-1359-2022; Sousa Uva, Miguel/AAR-9327-2020;
   Castaldo, Giuseppe/AAC-6782-2022
OI Kocher, Gregor Jan/0000-0001-6531-2919; Sousa Uva,
   Miguel/0000-0001-6353-653X; Schmid, Ralph Alexander/0000-0003-0699-079X;
   Abu-Omar, Yasir/0009-0005-0728-9884; Licht, Peter/0000-0003-1270-8068; 
CR Abbas G, 2009, SURGERY, V146, P749, DOI 10.1016/j.surg.2009.06.058
   [Anonymous], 2004, CLIN INFECT DIS
   Bennett-Guerrero E, 2010, JAMA-J AM MED ASSOC, V304, P755, DOI 10.1001/jama.2010.1152
   Biancari F, 2013, WORLD J SURG, V37, P1051, DOI 10.1007/s00268-013-1951-7
   Biefer HRC, 2012, EUR J CARDIO-THORAC, V42, P306, DOI 10.1093/ejcts/ezr326
   Borger MA, 1998, ANN THORAC SURG, V65, P1050, DOI 10.1016/S0003-4975(98)00063-0
   Bratzler DW, 2006, CLIN INFECT DIS, V43, P322, DOI 10.1086/505220
   Braxton John H, 2004, Semin Thorac Cardiovasc Surg, V16, P70
   Bryan CS, 2013, TEX HEART I J, V40, P125
   Bufkin BL, 1996, ANN THORAC SURG, V61, P1447, DOI 10.1016/0003-4975(96)00053-7
   Coia JE, 2006, J HOSP INFECT, V63, pS1, DOI 10.1016/j.jhin.2006.01.001
   COSGROVE DM, 1988, J THORAC CARDIOV SUR, V95, P850
   Cowan KN, 2005, ANN THORAC SURG, V80, P2205, DOI 10.1016/j.athoracsur.2005.04.005
   Crabtree Traves D, 2004, Semin Thorac Cardiovasc Surg, V16, P53
   Damiani G, 2011, J PLAST RECONSTR AES, V64, P1119, DOI 10.1016/j.bjps.2010.11.022
   Domkowski PW, 2003, J THORAC CARDIOV SUR, V126, P386, DOI 10.1016/S0022-5223(03)00352-0
   Doty JR, 1999, ANN THORAC SURG, V67, P1111, DOI 10.1016/S0003-4975(99)00145-9
   Douville EC, 2004, ANN THORAC SURG, V78, P1659, DOI 10.1016/j.athoracsur.2004.04.082
   Engelman R, 2007, ANN THORAC SURG, V83, P1569, DOI 10.1016/j.athoracsur.2006.09.046
   Ennker IC, 2009, J CARDIOTHORAC SURG, V4, DOI 10.1186/1749-8090-4-5
   ESTRERA AS, 1983, SURG GYNECOL OBSTET, V157, P545
   Falagas ME, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0064741
   Filsoufi F, 2009, J CARDIOTHOR VASC AN, V23, P488, DOI 10.1053/j.jvca.2009.02.007
   Fowler VG, 2005, CIRCULATION, V112, pI358, DOI 10.1161/CIRCULATIONAHA.104.525790
   Garcia Ana Maria, 2003, Biomedica, V23, P173
   Garey KW, 2006, J CHEMOTHERAPY, V18, P402, DOI 10.1179/joc.2006.18.4.402
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Graf K, 2010, EUR J CARDIO-THORAC, V37, P893, DOI 10.1016/j.ejcts.2009.10.005
   GROSSI EA, 1991, J THORAC CARDIOV SUR, V102, P342
   Gummert JF, 2002, THORAC CARDIOV SURG, V50, P87, DOI 10.1055/s-2002-26691
   Harrington G, 2004, INFECT CONT HOSP EP, V25, P472, DOI 10.1086/502424
   Heits N, 2014, ANN THORAC SURG, V97, P1029, DOI 10.1016/j.athoracsur.2013.11.014
   Hillis LD, 2011, CIRCULATION, V124, P2610, DOI 10.1161/CIR.0b013e31823b5fee
   Horan TC, 2008, AM J INFECT CONTROL, V36, P309, DOI 10.1016/j.ajic.2008.03.002
   Jakobsson J, 2011, WORLDV EVID-BASED NU, V8, P143, DOI 10.1111/j.1741-6787.2010.00201.x
   Kallen AJ, 2005, INFECT CONT HOSP EP, V26, P916, DOI 10.1086/505453
   Kanafani ZA, 2009, INFECT CONT HOSP EP, V30, P242, DOI 10.1086/596015
   Kohli M, 2003, INFECT CONT HOSP EP, V24, P17, DOI 10.1086/502110
   Kowalewski M, 2015, J THORAC CARDIOV SUR, V149, P1631, DOI 10.1016/j.jtcvs.2015.01.034
   KRETER B, 1992, J THORAC CARDIOV SUR, V104, P590
   Lador A, 2012, J ANTIMICROB CHEMOTH, V67, P541, DOI 10.1093/jac/dkr470
   Le Guillou V, 2011, J HOSP INFECT, V79, P236, DOI 10.1016/j.jhin.2011.07.004
   LOOP FD, 1990, ANN THORAC SURG, V49, P179, DOI 10.1016/0003-4975(90)90136-T
   Losanoff JE, 2002, EUR J CARDIO-THORAC, V21, P831, DOI 10.1016/S1010-7940(02)00124-0
   LOYD JE, 1988, MEDICINE, V67, P295, DOI 10.1097/00005792-198809000-00002
   Lu JCY, 2003, EUR J CARDIO-THORAC, V23, P943, DOI 10.1016/S1010-7940(03)00137-4
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Marty-Ané CH, 1999, ANN THORAC SURG, V68, P212, DOI 10.1016/S0003-4975(99)00453-1
   MCDONALD WS, 1989, SOUTH MED J, V82, P1361, DOI 10.1097/00007611-198911000-00008
   Mekontso-Dessap A, 2001, CLIN INFECT DIS, V32, P877, DOI 10.1086/319355
   Mertz D, 2011, ANN SURG, V254, P48, DOI 10.1097/SLA.0b013e318214b7e4
   Misthos P, 2007, J ORAL MAXIL SURG, V65, P635, DOI 10.1016/j.joms.2006.06.287
   Obdeijn MC, 1999, ANN THORAC SURG, V68, P2358, DOI 10.1016/S0003-4975(99)01159-5
   Omran AS, 2007, BMC INFECT DIS, V7, DOI 10.1186/1471-2334-7-112
   Perl TM, 2002, NEW ENGL J MED, V346, P1871, DOI 10.1056/NEJMoa003069
   Petzina R, 2010, EUR J CARDIO-THORAC, V38, P110, DOI 10.1016/j.ejcts.2010.01.028
   Prziborowski J, 2008, ANN THORAC SURG, V85, P1002, DOI 10.1016/j.athoracsur.2007.10.036
   Raja Shahzad G, 2007, Interact Cardiovasc Thorac Surg, V6, P523, DOI 10.1510/icvts.2007.157370
   Ridder GJ, 2010, ANN SURG, V251, P528, DOI 10.1097/SLA.0b013e3181c1b0d1
   Ridderstolpe L, 2001, EUR J CARDIO-THORAC, V20, P1168, DOI 10.1016/S1010-7940(01)00991-5
   Russo PL, 2002, INFECT CONT HOSP EP, V23, P372, DOI 10.1086/502068
   Schimmer C, 2008, ANN THORAC SURG, V86, P1897, DOI 10.1016/j.athoracsur.2008.08.071
   Shaker H, 2010, EUR J CARDIO-THORAC, V38, P216, DOI 10.1016/j.ejcts.2010.01.030
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Terpstra S, 1999, J HOSP INFECT, V43, P195, DOI 10.1053/jhin.1999.0636
   Tom TSM, 2009, ANN THORAC SURG, V88, P695, DOI 10.1016/j.athoracsur.2009.02.010
   Trautmann M, 2008, CHEMOTHERAPY, V54, P9, DOI 10.1159/000112312
   van Rijen MML, 2008, J ANTIMICROB CHEMOTH, V61, P254, DOI 10.1093/jac/dkm480
   van Wingerden JJ, 2014, J CARDIOTHORAC SURG, V9, DOI 10.1186/s13019-014-0179-4
   Vogel SB, 2005, ANN SURG, V241, P1016, DOI 10.1097/01.sla.0000164183.91898.74
   Webster J, 2014, COCHRANE DB SYST REV
   Webster J, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub3
   Wertheim HFL, 2005, LANCET INFECT DIS, V5, P751, DOI 10.1016/S1473-3099(05)70295-4
   WHEATLEY M J, 1990, Annals of Thoracic Surgery, V49, P780
   WILEY AM, 1979, CLIN ORTHOP RELAT R, P150
   WOUTERS R, 1994, TEX HEART I J, V21, P183
   Zeitani J, 2006, J THORAC CARDIOV SUR, V132, P38, DOI 10.1016/j.jtcvs.2006.03.015
   Zerr KJ, 1997, ANN THORAC SURG, V63, P356
NR 78
TC 158
Z9 195
U1 0
U2 7
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1010-7940
EI 1873-734X
J9 EUR J CARDIO-THORAC
JI Eur. J. Cardio-Thorac. Surg.
PD JAN
PY 2017
VL 51
IS 1
BP 10
EP 25
DI 10.1093/ejcts/ezw326
PG 16
WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology; Respiratory System; Surgery
GA EP5JS
UT WOS:000397415400004
PM 28077503
OA Green Submitted, Bronze
DA 2026-07-24
ER

PT J
AU Schepers, T
   Rammelt, S
AF Schepers, Tim
   Rammelt, Stefan
TI Complex Foot Injury Early and Definite Management
SO FOOT AND ANKLE CLINICS
LA English
DT Article
DE Complex foot; Reconstruction; Amputation; Outcome
ID PRESSURE WOUND THERAPY; HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED
   CLOSURE; SEVERE OPEN FRACTURES; QUALITY-OF-LIFE; LOWER-LIMB AMPUTATION;
   SOFT-TISSUE COVERAGE; COMPARTMENT SYNDROME; LOWER-EXTREMITY; MANGLED
   EXTREMITY
AB Complex foot occur infrequently, but are life-changing events; treatment is difficult and, if the necessary facilities are not available, referral should be considered. The first step in severe trauma should be the trauma screening and resuscitation according to the ABCDE principle following the Advanced Trauma Life Support system. The initial treatment of a complex foot injury consists of preventing progression of ischemia/necrosis, prevention of infection, and considering salvage or amputation. Definitive treatment (salvage) consists of anatomic reconstruction with stable internal fixation and early soft tissue coverage followed by aggressive rehabilitation and adequate orthopedic shoe modifications. Overall, the prognosis is hard to predict and determined by the severity of injury, comorbidities, complications, secondary interventions, and individual demands.
C1 [Schepers, Tim] Univ Amsterdam, Acad Med Ctr, Trauma Unit, Meibergdreef 9,POB 22660, NL-1100 Amsterdam, Netherlands.
   [Rammelt, Stefan] Univ Ctr Orthopaed & Traumatol, Univ Hosp Carl Gustav Carus, Fetscherstrasse 74, D-01307 Dresden, Germany.
C3 University of Amsterdam; Technische Universitat Dresden; Carl Gustav
   Carus University Hospital
RP Schepers, T (通讯作者)，Univ Amsterdam, Acad Med Ctr, Trauma Unit, Meibergdreef 9,POB 22660, NL-1100 Amsterdam, Netherlands.
EM t.schepers@amc.nl
RI ; Rammelt, Stefan/AAE-5863-2019
OI Schepers, Tim/0000-0003-1172-4939; Rammelt, Stefan/0000-0003-1141-6493
CR Acello A N, 1995, J Foot Ankle Surg, V34, P329
   Agel J, 2014, J ORTHOP TRAUMA, V28, P300, DOI 10.1097/BOT.0b013e3182a70f39
   Ahmed N, 2013, J PAKISTAN ORTHOP AS, V25, P35
   Akula M, 2011, INJURY, V42, P1194, DOI 10.1016/j.injury.2010.05.003
   Amtsberg G, 2004, TRAUMA BERUFSKRANKH, V3, P182
   Anagnostakos K, 2005, J BIOMED MATER RES B, V72B, P373, DOI 10.1002/jbm.b.30171
   Anagnostakos K, 2009, J BIOMED MATER RES B, V90B, P467, DOI 10.1002/jbm.b.31281
   Baechler MF, 2010, FOOT ANKLE CLIN, V15, P113, DOI 10.1016/j.fcl.2009.10.006
   Bakota B, 2012, COLLEGIUM ANTROPOL, V36, P1419
   Beals TC, 2001, ORTHOP CLIN N AM, V32, P205, DOI 10.1016/S0030-5898(05)70204-2
   Bevevino AJ, 2014, CLIN ORTHOP RELAT R, V472, P3002, DOI 10.1007/s11999-013-3382-z
   Bhandari M, 2015, NEW ENGL J MED, V373, P2629, DOI 10.1056/NEJMoa1508502
   Bistolfi Alessandro, 2011, ISRN Orthop, V2011, P290851, DOI 10.5402/2011/290851
   Blum ML, 2012, J ORTHOP TRAUMA, V26, P499, DOI 10.1097/BOT.0b013e31824133e3
   Bluman EM, 2010, FOOT ANKLE CLIN, V15, P1, DOI 10.1016/j.fcl.2009.11.004
   BONANNI F, 1993, J TRAUMA, V34, P99, DOI 10.1097/00005373-199301000-00019
   BONUTTI PM, 1986, J BONE JOINT SURG AM, V68A, P1449, DOI 10.2106/00004623-198668090-00023
   Bosse MJ, 2005, J BONE JOINT SURG AM, V87A, P2601, DOI 10.2106/JBJS.C.00671
   Bosse MJ, 2002, NEW ENGL J MED, V347, P1924, DOI 10.1056/NEJMoa012604
   Bosse MJ, 2001, J BONE JOINT SURG AM, V83A, P3, DOI 10.2106/00004623-200101000-00002
   Bouachour G, 1996, J TRAUMA, V41, P333, DOI 10.1097/00005373-199608000-00023
   Brenner P, 2001, WORLD J SURG, V25, P603, DOI 10.1007/s002680020150
   Brown KV, 2009, J TRAUMA, V66, pS93, DOI 10.1097/TA.0b013e31819cdcb0
   BRUMBACK RJ, 1994, J BONE JOINT SURG AM, V76A, P1162, DOI 10.2106/00004623-199408000-00006
   Buettner MF, 2007, EMERG MED CLIN N AM, V25, P177, DOI 10.1016/j.emc.2007.01.008
   Burdette TE, 2009, J REHABIL RES DEV, V46, P385, DOI 10.1682/JRRD.2008.08.0110
   Busse JW, 2007, J ORTHOP TRAUMA, V21, P70, DOI 10.1097/BOT.0b013e31802cbc43
   Carlson Russell M, 2014, Foot Ankle Spec, V7, P102, DOI 10.1177/1938640014522097
   Carsenti-Etesse H, 1999, EUR J CLIN MICROBIOL, V18, P315, DOI 10.1007/PL00015012
   Chandran Prakash, 2006, J Foot Ankle Surg, V45, P308, DOI 10.1053/j.jfas.2006.06.002
   Chung KC, 2009, PLAST RECONSTR SURG, V124, P1965, DOI 10.1097/PRS.0b013e3181bcf156
   Court-Brown C, 2013, FOOT ANKLE INT, V34, P323, DOI 10.1177/1071100712466232
   Court-Brown CM, 2006, INJURY, V37, P691, DOI 10.1016/j.injury.2006.04.130
   Court-Brown CM, 2012, INJURY, V43, P891, DOI 10.1016/j.injury.2011.12.007
   David A, 1996, FOOT ANKLE INT, V17, P334, DOI 10.1177/107110079601700607
   De Boer AS, 2014, BMC MUSCULOSKEL DIS, V15, DOI 10.1186/1471-2474-15-128
   Demiralp Bahtiyar, 2014, Eur J Orthop Surg Traumatol, V24, P621, DOI 10.1007/s00590-013-1345-4
   Dias MD, 2008, UNDERSEA HYPERBAR M, V35, P53
   Dickens Jonathan F, 2013, J Bone Joint Surg Am, V95, pe24, DOI 10.2106/JBJS.L.00003
   Durham RM, 1996, AM J SURG, V172, P569, DOI 10.1016/S0002-9610(96)00245-0
   Eberl R, 2011, INJURY, V42, P1171, DOI 10.1016/j.injury.2009.08.005
   Eisele R, 2008, UNFALLCHIRURG, V111, P796, DOI 10.1007/s00113-008-1495-8
   Ellington JK, 2013, J ORTHOP TRAUMA, V27, P43, DOI 10.1097/BOT.0b013e31825121b6
   Fakhouri A J, 1992, J Orthop Trauma, V6, P223, DOI 10.1097/00005131-199206000-00015
   Farber A, 2012, INJURY, V43, P1486, DOI 10.1016/j.injury.2011.06.006
   Ferrao P, 2012, FOOT ANKLE INT, V33, P173, DOI 10.3113/FAI.2012.0173
   Ferreira RC, 2010, FOOT ANKLE INT, V31, P113, DOI 10.3113/FAI.2010.0113
   Fildes B, 1997, ACCIDENT ANAL PREV, V29, P785, DOI 10.1016/S0001-4575(97)00047-X
   Fodor L, 2012, INT J BURNS TRAUMA, V2, P51
   Frink M, 2010, CLIN ORTHOP RELAT R, V468, P940, DOI 10.1007/s11999-009-0891-x
   Fulkerson E, 2003, FOOT ANKLE INT, V24, P180, DOI 10.1177/107110070302400214
   GREGORY RT, 1985, J TRAUMA, V25, P1147, DOI 10.1097/00005373-198512000-00005
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   HAGBERG E, 1992, PROSTHET ORTHOT INT, V16, P168
   Halawi MJ, 2015, ORTHOPEDICS, V38, pE1025, DOI 10.3928/01477447-20151020-12
   Han FC, 2015, J FOOT ANKLE SURG, V54, P417, DOI 10.1053/j.jfas.2014.09.015
   Hansen ST, 2001, ORTHOP CLIN N AM, V32, P181, DOI 10.1016/S0030-5898(05)70201-7
   Hauser Carl J, 2006, Surg Infect (Larchmt), V7, P379
   HECKMAN JD, 1989, CLIN ORTHOP RELAT R, P105
   HELFET DL, 1990, CLIN ORTHOP RELAT R, P80
   Hinck D, 2010, MIL MED, V175, P173, DOI 10.7205/MILMED-D-09-00075
   Holbrook TL, 1998, J TRAUMA, V45, P315, DOI 10.1097/00005373-199808000-00018
   Holbrook TL, 1999, J TRAUMA, V46, P765, DOI 10.1097/00005373-199905000-00003
   Hoogendoorn JM, 2001, INJURY, V32, P329, DOI 10.1016/S0020-1383(00)00250-3
   Hoogendoorn JM, 2002, EUR J TRAUMA, V28, P1, DOI DOI 10.1007/S00068-002-1131-1
   HOWE HR, 1987, AM SURGEON, V53, P205
   Husain ZS, 2016, J FOOT ANKLE SURG, V55, P1234, DOI 10.1053/j.jfas.2015.06.004
   Ingram R, 1993, ORTHOPAEDICS TRAUMA, V7, P19, DOI DOI 10.1016/0268-0890(93)90006-D
   Jacobs C, 2011, OPER ORTHOP TRAUMATO, V23, P306, DOI 10.1007/s00064-011-0043-9
   JACOBS LGH, 1991, INJURY, V22, P463, DOI 10.1016/0020-1383(91)90130-7
   Joethy J, 2013, SINGAP MED J, V54, P620
   JOHANSEN K, 1990, J TRAUMA, V30, P568, DOI 10.1097/00005373-199005000-00007
   Johnson Brent A, 2005, J Foot Ankle Surg, V44, P177, DOI 10.1053/j.jfas.2005.02.007
   JOHNSON EE, 1993, CLIN ORTHOP RELAT R, P118
   Jupiter DC, 2012, J FOOT ANKLE SURG, V51, P317, DOI 10.1053/j.jfas.2012.01.001
   Kaplan M, 2009, ADV SKIN WOUND CARE, V22, P128, DOI 10.1097/01.ASW.0000305451.71811.d5
   Karger C, 2012, ORTHOP TRAUMATOL-SUR, V98, P97, DOI 10.1016/j.otsr.2011.11.001
   Kenzora J E, 1981, Foot Ankle, V1, P348
   Kinner B, 2011, J TRAUMA, V70, P159, DOI 10.1097/TA.0b013e3181fef5eb
   Klaue K, 2004, FOOT ANKLE CLIN, V9, P10
   Klaue Kaj, 2004, Foot Ankle Clin, V9, P583, DOI 10.1016/j.fcl.2004.05.003
   Large TM, 2012, J ORTHOP TRAUMA, V26, P506, DOI 10.1097/BOT.0b013e31825354ce
   Largey A, 2009, ORTHOP TRAUMATOL-SUR, V95, P301, DOI 10.1016/j.otsr.2009.02.005
   Liu DSH, 2012, INJURY, V43, P772, DOI 10.1016/j.injury.2011.09.003
   Loos MS, 2010, ANN PLAS SURG, V65, P573, DOI 10.1097/SAP.0b013e3181d50e3e
   MacFarlane C, 2000, J R Army Med Corps, V146, P185
   MacMahon A, 2016, FOOT ANKLE INT, V37, P355, DOI 10.1177/1071100715617743
   Manoli A, 1997, FOOT ANKLE INT, V18, P598, DOI 10.1177/107110079701800914
   MANOLI A, 1993, FOOT ANKLE, V14, P339, DOI 10.1177/107110079301400606
   MCNAMARA MG, 1994, J ORTHOP TRAUMA, V8, P81, DOI 10.1097/00005131-199404000-00001
   Mittlmeier T, 2011, UNFALLCHIRURG, V114, P893, DOI 10.1007/s00113-011-1983-0
   MITTLMEIER T, 1991, CLIN ORTHOP RELAT R, P241
   Moniz MP, 1997, AM SURGEON, V63, P24
   Musharrafieh R, 1999, J RECONSTR MICROSURG, V15, P501, DOI 10.1055/s-2007-1000129
   Mutschler W, 2001, UNFALLCHIRURG, V104, P102, DOI 10.1007/s001130050699
   MYERSON M, 1993, CLIN ORTHOP RELAT R, P142
   MYERSON MS, 1994, J ORTHOP TRAUMA, V8, P343, DOI 10.1097/00005131-199408000-00012
   Neut D, 2001, J ANTIMICROB CHEMOTH, V47, P885, DOI 10.1093/jac/47.6.885
   OESTERN HJ, 1985, UNFALLCHIRURG, V88, P465
   Ojike NI, 2009, ACTA ORTHOP BELG, V75, P573
   OMER GE, 1972, ARCH SURG-CHICAGO, V105, P696
   Ovaska MT, 2016, FOOT ANKLE INT, V37, P401, DOI 10.1177/1071100715609182
   Pape HC, 1999, CHIRURG, V70, P1287, DOI 10.1007/s001040050781
   PATZAKIS MJ, 1983, CLIN ORTHOP RELAT R, P36
   Patzakis MJ, 2000, J ORTHOP TRAUMA, V14, P529, DOI 10.1097/00005131-200011000-00002
   Pedrini G, 2011, J ORTHOP TRAUMA, V25, P180, DOI 10.1097/BOT.0b013e3181d4be0f
   Penn-Barwell JG, 2011, INJURY, V42, P1474, DOI 10.1016/j.injury.2011.07.005
   Probst C, 2010, INJURY, V41, P210, DOI 10.1016/j.injury.2009.10.009
   Rajasekaran S, 2005, INDIAN J ORTHOP, V39, P4
   Ramasamy A, 2011, J TRAUMA, V71, P1694, DOI 10.1097/TA.0b013e318227a999
   Rammelt S, 2005, UNFALLCHIRURG, V108, P858, DOI 10.1007/s00113-005-0993-1
   Rammelt S, 2011, OPER ORTHOP TRAUMATO, V23, P265, DOI 10.1007/s00064-011-0042-x
   Rammelt S, 2008, EUR J TRAUMA EMERG S, V34, P237, DOI 10.1007/s00068-008-7163-4
   Rammelt Stefan, 2004, Foot Ankle Clin, V9, P455, DOI 10.1016/j.fcl.2004.05.001
   Richter M, 2001, J ORTHOP TRAUMA, V15, P287, DOI 10.1097/00005131-200105000-00009
   Roberts Craig S, 2005, Instr Course Lect, V54, P447
   ROBERTSON PA, 1991, J BONE JOINT SURG BR, V73, P816, DOI 10.1302/0301-620X.73B5.1894673
   Rodriguez L, 2014, J TRAUMA ACUTE CARE, V77, P400, DOI 10.1097/TA.0000000000000398
   RUSSELL WL, 1991, ANN SURG, V213, P473, DOI 10.1097/00000658-199105000-00013
   Sands AK, 2015, Fuß & Sprunggelenk, V13, P11, DOI [10.1016/j.fuspru.2015.01.002, 10.1016/j.fuspru.2015.01.002, DOI 10.1016/J.FUSPRU.2015.01.002]
   Schade VL, 2010, J FOOT ANKLE SURG, V49, P55, DOI 10.1053/j.jfas.2009.06.010
   Schepers T, 2012, Foot Ankle Surg, V18, P84, DOI 10.1016/j.fas.2011.04.004
   Schlatterer DR, 2015, CLIN ORTHOP RELAT R, V473, P1802, DOI 10.1007/s11999-015-4140-1
   Seeley DG, 1996, J BONE MINER RES, V11, P1347
   Seibert Franz Josef, 2003, Clin Podiatr Med Surg, V20, P159, DOI 10.1016/S0891-8422(02)00057-5
   Seligson D, 2010, ORTHOPEDICS, V33, P868, DOI 10.3928/01477447-20101021-36
   Shawen SB, 2010, FOOT ANKLE CLIN, V15, P63, DOI 10.1016/j.fcl.2009.11.005
   STABILE DE, 1990, J AM PODIAT MED ASSN, V80, P345
   Stalp M, 2002, J TRAUMA, V52, P1160, DOI 10.1097/00005373-200206000-00023
   Stannard JP, 2012, J ORTHOP TRAUMA, V26, P37, DOI 10.1097/BOT.0b013e318216b1e5
   Stannard JP, 2010, INJURY, V41, P780, DOI 10.1016/j.injury.2009.08.011
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Stinner DJ, 2012, J ORTHOP TRAUMA, V26, P512, DOI 10.1097/BOT.0b013e318251291b
   Strauss MB, 2012, UNDERSEA HYPERBAR M, V39, P847
   Suzuki T, 2014, J ORTHOP SURG-HONG K, V22, P30, DOI 10.1177/230949901402200109
   Swiontkowski MF, 2002, J TRAUMA, V52, P641, DOI 10.1097/00005373-200204000-00005
   SWOBODA B, 1991, UNFALLCHIRURG, V94, P262
   Taniguchi A, 2003, CLIN ORTHOP RELAT R, P322, DOI 10.1097/01.blo.0000079444.64912.d6
   Taylor SM, 2005, J VASC SURG, V42, P227, DOI 10.1016/j.jvs.2005.04.015
   Thakur NA, 2012, J BONE JOINT SURG AM, V94A, P1030, DOI 10.2106/JBJS.J.02000
   Tran T, 2002, FOOT ANKLE INT, V23, P340, DOI 10.1177/107110070202300409
   TSCHERNE H, 1982, UNFALLHEILKUNDE, V85, P111
   TSCHERNE H, 1983, ORTHOPADE, V12, P9
   Turchin DC, 1999, J ORTHOP TRAUMA, V13, P1, DOI 10.1097/00005131-199901000-00001
   von Ruden Christian, 2013, J Trauma Manag Outcomes, V7, P4, DOI 10.1186/1752-2897-7-4
   Wang HC, 2010, FOOT ANKLE INT, V31, P959, DOI 10.3113/FAI.2010.0959
   Warner Meredith, 2010, Orthopedics, V33, P77, DOI 10.3928/01477447-20100104-06
   Wattel F, 1998, ANAESTHESIA, V53, P63
   Weninger P, 2005, ZBL CHIR, V130, P485, DOI 10.1055/s-2005-836912
   Weninger P, 2008, J TRAUMA, V65, P799, DOI 10.1097/TA.0b013e3181820dae
   Westphal T, 2002, ZBL CHIR, V127, P238, DOI 10.1055/s-2002-24244
   WRIGHT JW, 1987, TECH ORTHOP, V2, P71
   Yazar S, 2004, PLAST RECONSTR SURG, V114, P1457, DOI 10.1097/01.PRS.0000138811.88807.65
   Zelle BA, 2005, INJURY, V36, P169, DOI 10.1016/j.injury.2004.06.004
   Zelle BA, 2014, J BONE JOINT SURG AM, V96-A, P91
   Zhang TY, 2016, J FOOT ANKLE SURG, V55, P112, DOI 10.1053/j.jfas.2015.07.023
   Zwipp H, 1997, ORTHOPADE, V26, P1046
   ZWIPP H, 1989, UNFALLCHIRURG, V92, P140
   ZWIPP H, 1991, UNFALLCHIRURG, V94, P274
   Zwipp H, 1993, MAJOR FRACTURES PILO, P123
NR 161
TC 12
Z9 23
U1 0
U2 2
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 1083-7515
EI 1558-1934
J9 FOOT ANKLE CLIN
JI Foot Ankle Clin.
PD MAR
PY 2017
VL 22
IS 1
BP 193
EP +
DI 10.1016/j.fcl.2016.09.014
PG 23
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA EP4KV
UT WOS:000397350300014
PM 28167063
DA 2026-07-24
ER

PT J
AU Miller, AT
   Byrn, JC
   Divino, CM
   Weber, KJ
AF Miller, Aaron T.
   Byrn, John C.
   Divino, Celia M.
   Weber, Kaare J.
TI Eikenella corrodens causing necrotizing Fasciitis after an elective
   inguinal hernia repair in an adult: A case report and literature review
SO AMERICAN SURGEON
LA English
DT Review
ID VACUUM-ASSISTED CLOSURE; INFECTION; MANAGEMENT; MORTALITY
AB We report an unusual case of necrotizing fasciitis in a 43-year-old man after elective inguinal hernia repair. The patient presented to the emergency department 9 days postoperatively with high fevers, tachycardia, and crepitus along his abdominal wall. He was treated with broad-spectrum antibiotics and underwent a diagnostic laparoscopy as well as a wide debridement of all necrotic tissue. Cultures grew out Eikenella corrodens, which, to our knowledge, has only been reported in one other case as a cause of necrotizing fasciitis. Patients can develop necrotizing fasciitis after elective, clean procedures and should be adequately resuscitated, undergo immediate surgical debridement, and receive antibiotics. Laparoscopy can be useful in determining if intraabdominal pathology is the cause of the infection and a wound vacuum-assisted device is a cost-effective way to decrease healing times.
C1 Mt Sinai Sch Med, Dept Surg, New York, NY USA.
C3 Icahn School of Medicine at Mount Sinai
RP Divino, CM (通讯作者)，5 E 98th St,15th Floor,Box 1259, New York, NY 10029 USA.
EM celia.divino@mountsinai.org
CR Andreasen TJ, 2001, PLAST RECONSTR SURG, V107, P1025, DOI 10.1097/00006534-200104010-00019
   Cox NH, 1999, BRIT J DERMATOL, V141, P613
   de Geus HRH, 2005, INTENS CARE MED, V31, P601, DOI 10.1007/s00134-004-2553-5
   Drake D B, 1998, J Emerg Med, V16, P403, DOI 10.1016/S0736-4679(98)00013-4
   FARRELL LD, 1988, PEDIATRICS, V82, P874
   Hasham S, 2005, BMJ-BRIT MED J, V330, P830, DOI 10.1136/bmj.330.7495.830
   Jallali N, 2005, AM J SURG, V189, P462, DOI 10.1016/j.amjsurg.2005.01.012
   Kihiczak GG, 2006, J EUR ACAD DERMATOL, V20, P365, DOI 10.1111/J.1468-3083.2006.01487.x
   Kostadinov S, 2005, PEDIATR DEVEL PATHOL, V8, P489, DOI 10.1007/s10024-005-0010-2
   Lambert KV, 2005, EUR J VASC ENDOVASC, V29, P219, DOI 10.1016/j.ejvs.2004.12.017
   MCHENRY CR, 1995, ANN SURG, V221, P558, DOI 10.1097/00000658-199505000-00013
   Mordehai J, 1997, PEDIATR SURG INT, V12, P538, DOI 10.1007/s003830050204
   Oczenski W, 2004, J CARDIOTHOR VASC AN, V18, P336, DOI 10.1053/j.jvca.2004.03.016
   Schroeder Janice L, 2005, AORN J, V82, P1031, DOI 10.1016/S0001-2092(06)60255-X
   Seal DV, 2001, CURR OPIN INFECT DIS, V14, P127, DOI 10.1097/00001432-200104000-00003
   Trent Jennifer T, 2002, Adv Skin Wound Care, V15, P135, DOI 10.1097/00129334-200205000-00010
   Wall DB, 2000, AM J SURG, V179, P17, DOI 10.1016/S0002-9610(99)00259-7
   Weil H, 2002, NEW ENGL J MED, V346, P1336, DOI 10.1056/NEJM200204253461721
   Wong Chin-Ho, 2005, Curr Opin Infect Dis, V18, P101, DOI 10.1097/01.qco.0000160896.74492.ea
   Zhiyong Zong, 2007, J Infect, V54, pe17, DOI 10.1016/j.jinf.2006.03.021
NR 20
TC 12
Z9 13
U1 0
U2 1
PU SOUTHEASTERN SURGICAL CONGRESS
PI ATLANTA
PA 141 WEST WIEUCA RD, STE B100, ATLANTA, GA 30342 USA
SN 0003-1348
J9 AM SURGEON
JI Am. Surg.
PD SEP
PY 2007
VL 73
IS 9
BP 876
EP 879
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 210QB
UT WOS:000249469600009
PM 17939416
DA 2026-07-24
ER

PT J
AU Kruse, CR
   Nuutila, K
   Lee, CCY
   Kiwanuka, E
   Singh, M
   Caterson, EJ
   Eriksson, E
   Sorensen, JA
AF Kruse, Carla R.
   Nuutila, Kristo
   Lee, Cameron C. Y.
   Kiwanuka, Elizabeth
   Singh, Mansher
   Caterson, Edward J.
   Eriksson, Elof
   Sorensen, Jens A.
TI The external microenvironment of healing skin wounds
SO WOUND REPAIR AND REGENERATION
LA English
DT Article
ID HYPERBARIC-OXYGEN THERAPY; VACUUM-ASSISTED CLOSURE; DIABETIC FOOT
   ULCERS; IN-VIVO; STAPHYLOCOCCUS-AUREUS; GROWTH BOUNDARIES; PRESSURE
   SENSOR; VENOUS ULCERS; PH; TEMPERATURE
AB The skin wound microenvironment can be divided into two main components that influence healing: the external wound microenvironment, which is outside the wound surface; and the internal wound microenvironment, underneath the surface, to which the cells within the wound are exposed. Treatment methods that directly alter the features of the external wound microenvironment indirectly affect the internal wound microenvironment due to the exchange between the two compartments. In this review, we focus on the effects of temperature, pressure (positive and negative), hydration, gases (oxygen and carbon dioxide), pH, and anti-microbial treatment on the wound. These factors are well described in the literature and can be modified with treatment methods available in the clinic. Understanding the roles of these factors in wound pathophysiology is of central importance in wound treatment.
C1 [Kruse, Carla R.; Nuutila, Kristo; Lee, Cameron C. Y.; Kiwanuka, Elizabeth; Singh, Mansher; Caterson, Edward J.; Eriksson, Elof] Harvard Univ, Brigham & Womens Hosp, Div Plast Surg, Sch Med, Boston, MA 02115 USA.
   [Kruse, Carla R.; Sorensen, Jens A.] Odense Univ Hosp, Dept Plast & Reconstruct Surg, DK-5000 Odense, Denmark.
C3 Harvard University; Harvard University Medical Affiliates; Brigham &
   Women's Hospital; Harvard Medical School; University of Southern
   Denmark; Odense University Hospital
RP Eriksson, E (通讯作者)，Harvard Univ, Brigham & Womens Hosp, Div Plast Surg, Sch Med, Boston, MA 02115 USA.
EM eeriksson@partners.org
RI Sørensen, Jens Ahm/D-6279-2014
OI Sørensen, Jens Ahm/0000-0003-4903-0094; Caterson,
   Edward/0000-0003-4024-650X; Kiwanuka, Elizabeth/0000-0003-3838-2684
CR [Anonymous], 2013, COCHRANE DB SYST REV
   Armstrong DG, 2007, AM J MED, V120, P1042, DOI 10.1016/j.amjmed.2007.06.028
   Martínez-Jiménez MA, 2013, PLAST RECONSTR SURG, V132, p1015E, DOI 10.1097/PRS.0b013e3182a806f0
   Babilas P, 2005, MICROCIRCULATION, V12, P477, DOI 10.1080/10739680591003314
   BENDY R H Jr, 1964, Antimicrob Agents Chemother (Bethesda), V10, P147
   Bernards MT, 2008, J BIOMED MATER RES A, V87A, P505, DOI 10.1002/jbm.a.31778
   Blackman E, 2010, OSTOMY WOUND MANAG, V56, P24
   Boateng JS, 2008, J PHARM SCI-US, V97, P2892, DOI 10.1002/jps.21210
   Bolton L L, 2000, Ostomy Wound Manage, V46, p51S
   Bolton LL, 2000, OSTOMY WOUND MANAG S, V46, p3S
   Britland S, 2012, BIOTECHNOL PROGR, V28, P917, DOI 10.1002/btpr.1561
   Campbell N, 2013, J WOUND CARE, V22, P401, DOI 10.12968/jowc.2013.22.8.401
   Camporesi EM, 2014, UNDERSEA HYPERBAR M, V41, P247
   Carreau A, 2011, J CELL MOL MED, V15, P1239, DOI 10.1111/j.1582-4934.2011.01258.x
   Castilla DM, 2012, ADV WOUND CARE, V1, P225, DOI 10.1089/wound.2011.0319
   Clausen I, 2011, IEEE ENG MED BIO, P1880, DOI 10.1109/IEMBS.2011.6090533
   Daeschlein G, 2013, INT WOUND J, V10, P9, DOI 10.1111/iwj.12175
   DeHennis AD, 2005, J MICROELECTROMECH S, V14, P12, DOI 10.1109/JMEMS.2004.839650
   Di Pietrantonio F, 2013, BIOSENS BIOELECTRON, V41, P328, DOI 10.1016/j.bios.2012.08.046
   Dreifke MB, 2015, MAT SCI ENG C-MATER, V48, P651, DOI 10.1016/j.msec.2014.12.068
   Duzgun AP, 2008, J FOOT ANKLE SURG, V47, P515, DOI 10.1053/j.jfas.2008.08.002
   Eisenbud DE, 2012, CLIN PLAST SURG, V39, P293, DOI 10.1016/j.cps.2012.05.001
   Ennis WJ, 2013, ADV WOUND CARE, V2, P369, DOI 10.1089/wound.2013.0449
   EVANS NTS, 1967, RESP PHYSIOL, V3, P21, DOI 10.1016/0034-5687(67)90020-5
   Fazli M, 2011, WOUND REPAIR REGEN, V19, P387, DOI 10.1111/j.1524-475X.2011.00681.x
   Fierheller M, 2010, ADV SKIN WOUND CARE, V23, P369, DOI 10.1097/01.ASW.0000383197.28192.98
   Fisher K, 2009, MICROBIOL-SGM, V155, P1749, DOI 10.1099/mic.0.026385-0
   Georgina G., 2007, Wounds UK, V3, P52, DOI DOI 10.1101/
   Goldman RJ, 2009, PM&R, V1, P471, DOI 10.1016/j.pmrj.2009.03.012
   Gordillo GM, 2008, CLIN EXP PHARMACOL P, V35, P957, DOI 10.1111/j.1440-1681.2008.04934.x
   Grice EA, 2012, ADV EXP MED BIOL, V946, P55, DOI 10.1007/978-1-4614-0106-3_4
   Hackl F, 2012, PLAST RECONSTR SURG, V129, p443E, DOI 10.1097/PRS.0b013e318241289c
   Hanson RR, 2005, VET CLIN N AM-EQUINE, V21, P105, DOI 10.1016/j.cveq.2004.11.006
   Hasmann A, 2011, DIAGN MICR INFEC DIS, V71, P12, DOI 10.1016/j.diagmicrobio.2010.09.009
   Hebra F., 1861, ALLGEMEINE WIENER ME, V6, P351
   Hettrick Heather, 2009, J Am Col Certif Wound Spec, V1, P20, DOI 10.1016/j.jcws.2008.10.002
   HILPERT P, 1963, AM J PHYSIOL, V205, P337, DOI 10.1152/ajplegacy.1963.205.2.337
   Hopf HW, 2007, ANTIOXID REDOX SIGN, V9, P1183, DOI 10.1089/ars.2007.1641
   HORIKOSHI T, 1986, J INVEST DERMATOL, V86, P424, DOI 10.1111/1523-1747.ep12285695
   Howard MA, 2013, WOUND REPAIR REGEN, V21, P503, DOI 10.1111/wrr.12069
   HUNT TK, 1967, AM J SURG, V114, P302, DOI 10.1016/0002-9610(67)90388-1
   James GA, 2008, WOUND REPAIR REGEN, V16, P37, DOI 10.1111/j.1524-475X.2007.00321.x
   JONKMAN MF, 1990, J INVEST DERMATOL, V94, P477, DOI 10.1111/1523-1747.ep12874624
   Junker JPE, 2015, PLAST RECONSTR SURG, V135, P151, DOI 10.1097/PRS.0000000000000801
   Junker JPE, 2013, ADV WOUND CARE, V2, P348, DOI 10.1089/wound.2012.0412
   Junker JPE, 2013, J CRANIOFAC SURG, V24, P12, DOI 10.1097/SCS.0b013e31827104fb
   Kairinos N, 2010, J PLAST RECONSTR AES, V63, P174, DOI 10.1016/j.bjps.2008.08.037
   Kalliainen Loree K., 2003, Pathophysiology, V9, P81, DOI 10.1016/S0928-4680(02)00079-2
   Kelechi Teresa J, 2003, J Wound Ostomy Continence Nurs, V30, P17, DOI 10.1067/mjw.2003.10
   Khan Aadil A, 2004, Int Wound J, V1, P233, DOI 10.1111/j.1742-4801.2004.00065.x
   Kiwanuka E, 2011, J AM COLL SURGEONS, V213, P728, DOI 10.1016/j.jamcollsurg.2011.08.020
   Kloth Luther C, 2002, Adv Skin Wound Care, V15, P270, DOI 10.1097/00129334-200211000-00008
   Korostynska O, 2008, IEEE SENS J, V8, P20, DOI 10.1109/JSEN.2007.912522
   Koyama T, 2011, J AM COLL SURGEONS, V212, P340, DOI 10.1016/j.jamcollsurg.2010.10.017
   Kranke P, 2012, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD004123.pub3, 10.1002/14651858.CD004123.pub4]
   Krock Bryan L, 2011, Genes Cancer, V2, P1117, DOI 10.1177/1947601911423654
   Krom BP, 2014, PHLEBOLOGY, V29, P168, DOI 10.1177/0268355514528845
   Lambers H., 2006, International Journal of Cosmetic Science, V28, P359, DOI 10.1111/j.1467-2494.2006.00344.x
   Lavery LA, 2004, DIABETES CARE, V27, P2642, DOI 10.2337/diacare.27.11.2642
   Leaper DJ, 2008, INT WOUND J, V5, P361, DOI 10.1111/j.1742-481X.2007.00406.x
   LENGHEDEN A, 1995, EUR J ORAL SCI, V103, P148, DOI 10.1111/j.1600-0722.1995.tb00016.x
   Löffler M, 2011, DIABETIC MED, V28, P175, DOI 10.1111/j.1464-5491.2010.03123.x
   Mauck KF, 2014, J VASC SURG, V60, p60S, DOI 10.1016/j.jvs.2014.04.059
   McColl David, 2007, Int J Surg, V5, P316, DOI 10.1016/j.ijsu.2007.02.008
   Mehmood N, 2014, J BIOMED MATER RES B, V102, P885, DOI 10.1002/jbm.b.33063
   Menke NB, 2007, CLIN DERMATOL, V25, P19, DOI 10.1016/j.clindermatol.2006.12.005
   Mercier RC, 2002, J ANTIMICROB CHEMOTH, V50, P19, DOI 10.1093/jac/dkf058
   Mouës CM, 2011, AM J SURG, V201, P544, DOI 10.1016/j.amjsurg.2010.04.029
   Müeller G, 2008, J ANTIMICROB CHEMOTH, V61, P1281, DOI 10.1093/jac/dkn125
   NADKARNI SR, 1971, ENZYMOLOGIA, V40, P286
   Nagoba BS, 2013, J INFECT PUBLIC HEAL, V6, P410, DOI 10.1016/j.jiph.2013.05.005
   Nair Brijesh, 2014, Indian Dermatol Online J, V5, P378, DOI 10.4103/2229-5178.137822
   Nakagami G, 2010, J WOUND CARE, V19, P465, DOI 10.12968/jowc.2010.19.11.79695
   Nuutila K, 2013, BURNS, V39, P687, DOI 10.1016/j.burns.2012.09.014
   O'Meara SM, 2001, BJS-BRIT J SURG, V88, P4, DOI 10.1046/j.1365-2168.2001.01631.x
   O'Meara S, 2009, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD000265.pub3
   Ohmedics Ltd, 2013, WOUNDSENSE PROD INF
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Orsted HL, 2012, INT WOUND J, V9, P271, DOI 10.1111/j.1742-481X.2012.00956.x
   Percival S. L., 2014, CRIT REV MICROBIOL, P1
   Phair J, 2011, ANALYST, V136, P4692, DOI 10.1039/c1an15675f
   Price P, 2000, J Wound Care, V9, P201
   Reish RG, 2009, WOUND REPAIR REGEN, V17, P806, DOI 10.1111/j.1524-475X.2009.00546.x
   Robson MC, 2006, WOUND REPAIR REGEN, V14, P649, DOI 10.1111/j.1524-475X.2006.00174.x
   Robson Martin C, 2007, J Burns Wounds, V6, pe6
   ROBSON MC, 1969, MIL MED, V134, P19, DOI 10.1093/milmed/134.1.19
   Ross C, 2011, EXP DERMATOL, V20, P58, DOI 10.1111/j.1600-0625.2010.01190.x
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   Schlierf R, 2007, J MICROMECH MICROENG, V17, pS98, DOI 10.1088/0960-1317/17/7/S06
   Schreml S, 2010, BRIT J DERMATOL, V163, P257, DOI 10.1111/j.1365-2133.2010.09804.x
   Sharpe JR, 2013, J BURN CARE RES, V34, pE201, DOI 10.1097/BCR.0b013e31825d5569
   Sibbald R Gary, 2003, Ostomy Wound Manage, V49, P24
   Smith MEB, 2013, ANN INTERN MED, V159, P39, DOI 10.7326/0003-4819-159-1-201307020-00007
   Springett R, 2007, ANTIOXID REDOX SIGN, V9, P1295, DOI 10.1089/ars.2007.1620
   Sridhar V, 2009, HYDROGEL BASED PASSI, V155
   Steed DL, 2006, WOUND REPAIR REGEN, V14, P680, DOI 10.1111/j.1524-475X.2006.00176.x
   Steinberg IM, 2009, SENSOR ACTUAT B-CHEM, V138, P120, DOI 10.1016/j.snb.2009.02.040
   Stewart CM, 2002, APPL ENVIRON MICROB, V68, P1864, DOI 10.1128/AEM.68.4.1864-1871.2002
   Svensjö T, 2000, PLAST RECONSTR SURG, V106, P602, DOI 10.1097/00006534-200009030-00012
   Tawfick W, 2009, EUR J VASC ENDOVASC, V38, P125, DOI 10.1016/j.ejvs.2009.03.027
   Taylor CT, 2011, J PHYSIOL-LONDON, V589, P797, DOI 10.1113/jphysiol.2010.201467
   Thomas DR, 2006, J AM MED DIR ASSOC, V7, P46, DOI 10.1016/j.jamda.2005.10.004
   Trent JT, 2005, OSTOMY WOUND MANAG, V51, P38
   Tsuji Takao, 2013, Open Respir Med J, V7, P6, DOI 10.2174/1874306401307010006
   Ubbink Dirk T, 2014, Surg Technol Int, V24, P99
   Valero A, 2009, INT J FOOD MICROBIOL, V133, P186, DOI 10.1016/j.ijfoodmicro.2009.05.023
   Vikram DS, 2007, ANTIOXID REDOX SIGN, V9, P1745, DOI 10.1089/ars.2007.1717
   Vranckx JJ, 2002, PLAST RECONSTR SURG, V110, P1680, DOI 10.1097/00006534-200212000-00009
   Walker HK, 1990, CLIN METHODS HIST PH
   Wang W, 2003, J PHYSIOL-LONDON, V549, P855, DOI 10.1113/jphysiol.2002.037994
   Whelan J, 2002, DRUG DISCOV TODAY, V7, P9, DOI 10.1016/S1359-6446(01)02129-8
   Whitney J, 2006, WOUND REPAIR REGEN, V14, P663, DOI 10.1111/j.1524-475X.2006.00175.x
   Wilkins RG, 2013, ADV SKIN WOUND CARE, V26, P160, DOI 10.1097/01.ASW.0000428861.26671.41
   WILMORE DW, 1977, ANN SURG, V186, P444, DOI 10.1097/00000658-197710000-00006
   WINTER GD, 1962, NATURE, V193, P293, DOI 10.1038/193293a0
   Wu P, 1996, BIOMATERIALS, V17, P1373, DOI 10.1016/0142-9612(96)87277-2
   Xue N, 2011, IEEE ENG MED BIO, P2854, DOI 10.1109/IEMBS.2011.6090788
   Zbuchea A, 2014, Ann Burns Fire Disasters, V27, P22
   Zhao G, 2013, ADV WOUND CARE, V2, P389, DOI 10.1089/wound.2012.0381
   Zuhaili B, 2010, PLAST RECONSTR SURG, V125, P855, DOI 10.1097/PRS.0b013e3181ccdc42
NR 120
TC 125
Z9 152
U1 8
U2 152
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1067-1927
EI 1524-475X
J9 WOUND REPAIR REGEN
JI Wound Repair Regen.
PD JUL-AUG
PY 2015
VL 23
IS 4
BP 456
EP 464
DI 10.1111/wrr.12303
PG 9
WC Cell Biology; Dermatology; Medicine, Research & Experimental; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cell Biology; Dermatology; Research & Experimental Medicine; Surgery
GA CQ7EG
UT WOS:000360765100170
PM 25857996
DA 2026-07-24
ER

PT J
AU Chen, WF
   Poulakidas, SJ
   Kowal-Vern, A
   Villare, RC
AF Chen, Wei F.
   Poulakidas, Stathis J.
   Kowal-Vern, Areta
   Villare, Robert C.
TI Trephination and Subatmospheric Pressure Therapy in the Management of
   Extremity Exposed Bone
SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
LA English
DT Article
DE Subatmospheric pressure therapy; Trephination; Extremity exposed bone
ID VACUUM-ASSISTED CLOSURE; SOFT-TISSUE DEFECTS; WOUND CONTROL;
   RECONSTRUCTION; EXPERIENCE; 4TH-DEGREE; BURN; TENDON; FLAPS; HAND
AB Background: Distal lower and upper extremity wounds with bone and tendon exposure present unique challenges to reconstructive surgeons. The limitations of the local anatomy usually make simpler reconstructive modalities such as primary closure and skin grafting difficult. As a result, wounds in this area, especially ones with bone or tendon exposures, are classically treated with free tissue transfer.
   Methods: Limb preservation using the combination of bone trephination and subatmospheric pressure therapy is described.
   Results: Six cases with preserved extremities are presented. Three cases illustrate extremity wound with bone and tendon exposure healing through pregrafting wound optimization (bone trephination) with the use of subatmospheric pressure therapy.
   Conclusions: This treatment may offer an alternative method of limb salvage, in cases where flaps or free tissue transfer are not possible or optimal.
C1 [Poulakidas, Stathis J.] Jr Hosp Cook Cty, Sumner L Koch Burn Ctr, Burn Serv, Dept Trauma,Div Burn Serv, Chicago, IL 60612 USA.
   [Chen, Wei F.] Univ Illinois, Dept Plast Surg, Chicago, IL USA.
   [Villare, Robert C.] Mem Hosp Salem Cty Wound & Vasc Ctr, Dept Surg, Vasc Surg Sect, Salem, NJ USA.
C3 University of Illinois System; University of Illinois Chicago;
   University of Illinois Chicago Hospital
RP Poulakidas, SJ (通讯作者)，Jr Hosp Cook Cty, Sumner L Koch Burn Ctr, Burn Serv, Dept Trauma,Div Burn Serv, Rm 3229,1901 W Harrison St, Chicago, IL 60612 USA.
EM spoulakdoc1@msn.com
OI Chen, Wei/0000-0002-4163-6641
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Aston SJ, 1997, GRABB SMITHS PLASTIC, P13
   BHATTACHARYA V, 1982, J TRAUMA, V22, P698, DOI 10.1097/00005373-198208000-00009
   Bollero D, 2007, WOUND REPAIR REGEN, V15, P589, DOI 10.1111/j.1524-475X.2007.00267.x
   Culliford AT, 2007, ANN PLAS SURG, V59, P18, DOI 10.1097/01.sap.0000262740.34106.1b
   Datiashvili RO, 2005, WOUNDS, V17, P206
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Dumont CE, 2004, ANN PLAS SURG, V53, P368, DOI 10.1097/01.sap.0000135138.45902.52
   GIBRAN NS, 1994, J TRAUMA, V37, P176, DOI 10.1097/00005373-199408000-00003
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Hallock GG, 2007, ANN PLAS SURG, V59, P473, DOI 10.1097/SAP.0b013e3181579dbb
   Hallock GG, 2005, PLAST RECONSTR SURG, V116, P1839, DOI 10.1097/01.prs.0000188840.06911.06
   Horch RE, 2008, J CUTAN MED SURG, V12, P223, DOI 10.2310/7750.2008.07073
   Latenser J, 1994, J DERMATOL SURG ONC, V17, P265
   Lee LF, 2008, PLAST RECONSTR SURG, V121, P1256, DOI 10.1097/01.prs.0000304237.54236.66
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Muangman P, 2006, ANN PLAS SURG, V57, P199, DOI 10.1097/01.sap.0000218636.61803.d6
   Nuchtern J. G., 1995, Journal of Burn Care and Rehabilitation, V16, P36, DOI 10.1097/00004630-199501000-00007
   Parrett BM, 2006, J BURN CARE RES, V27, P34, DOI 10.1097/01.bcr.0000192265.20514.c5
   Pradier Jean-Philippe, 2007, J Burns Wounds, V6, pe1
   Repta R, 2005, ANN PLAS SURG, V55, P367, DOI 10.1097/01.sap.0000181342.25065.60
   Stefanacci HA, 2003, J TRAUMA, V55, P707, DOI 10.1097/01.TA.0000058125.48949.69
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Windhofer C, 2006, BURNS, V32, P261, DOI 10.1016/j.burns.2005.06.018
   Yazar S, 2004, PLAST RECONSTR SURG, V114, P1457, DOI 10.1097/01.PRS.0000138811.88807.65
   Yoon SW, 2007, J BURN CARE RES, V28, P521, DOI 10.1097/BCR.0B013e318053DAAB
NR 26
TC 4
Z9 5
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0022-5282
EI 1529-8809
J9 J TRAUMA
JI J. Trauma-Injury Infect. Crit. Care
PD DEC
PY 2010
VL 69
IS 6
BP 1591
EP 1596
DI 10.1097/TA.0b013e3181edba5e
PG 6
WC Critical Care Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine; Surgery
GA 695RT
UT WOS:000285391000061
PM 21150535
DA 2026-07-24
ER

PT J
AU Müller, DD
   Tilgen, W
AF Müller, DD
   Tilgen, W
TI Established and actual procedures in wound healing
SO HAUTARZT
LA German
DT Article
ID DIABETIC FOOT ULCERS; CHRONIC VENOUS ULCERATION; IODINE LIPOSOME
   HYDROGEL; VACUUM-ASSISTED CLOSURE; CONTROLLED-TRIAL; BED PREPARATION;
   LEG ULCERS; THERAPY; MANAGEMENT; SKIN
AB Most chronic wounds are caused by arterial or venous vascular disease. Wound care is an interdisciplinary task and economic challenge. Numerous new wound dressings and treatment methods have been introduced recently. Basic research has enhanced our understanding of stimulation and inhibition of wound healing. Well-constructed clinical studies have shown some traditional approaches to be effective and others, less so. Successful wound healing requires treatment of the underlying disease as well as correction of local factors that may delay healing. The choice of dressings must be based on continuous re-assessment of the wound. Modern approaches for the most common types of chronic wounds, as well as options such as vacuum treatment and tissue-engineered skin are presented along with information on latest rules for reimbursement for wound care in Germany.
C1 Univ Klinikum Saarlandes, Klin Dermatol Venerol & Allergol, D-66421 Homburg, Germany.
C3 Universitatsklinikum des Saarlandes
RP Müller, DD (通讯作者)，Univ Klinikum Saarlandes, Klin Dermatol Venerol & Allergol, Gebaude 18, D-66421 Homburg, Germany.
EM haddil@uniklinik-saarland.de
CR [Anonymous], ZFW
   Banwell P E, 2003, J Wound Care, V12, P22
   Barwell JR, 2004, LANCET, V363, P1854, DOI 10.1016/S0140-6736(04)16353-8
   BAUMLER L, 2003, GEFASSCHIRURGIE, V8, P282
   Bowler PG, 1999, INT J DERMATOL, V38, P573, DOI 10.1046/j.1365-4362.1999.00738.x
   Coerper S, 2004, ARCH SURG-CHICAGO, V139, P251, DOI 10.1001/archsurg.139.3.251
   Cullen B, 2002, WOUND REPAIR REGEN, V10, P16, DOI 10.1046/j.1524-475X.2002.10703.x
   DILLMULLER D, 2001, STANDARDS TRENDS OPE, V17, pS85
   Dissemond J, 2003, HAUTARZT, V54, P1073, DOI 10.1007/s00105-003-0582-6
   Dissemond J, 2003, HAUTARZT, V54, P524, DOI 10.1007/s00105-003-0520-7
   DISSEMOND J, 2004, Z FLUGWISS WELTRAUM, V9, P48
   Fleischmann W, 1998, UNFALLCHIRURG, V101, P649, DOI 10.1007/s001130050318
   Gallenkemper G, 1996, PHLEBOLOGIE, V25, P254
   Gillitzer R, 2002, HAUTARZT, V53, P130, DOI 10.1007/s00105-001-0335-3
   GRASSBERGER M, 2003, MMW, V153, P198
   Griffiths R D, 2001, J Wound Care, V10, P407
   HACH W, 2000, GEFASSCHIRURGIE, V5, P255
   Hafner J, 2000, J AM ACAD DERMATOL, V43, P1001, DOI 10.1067/mjd.2000.108375
   HALMNILL C, 2004, ZFW, V9
   Harding KG, 2002, BMJ-BRIT MED J, V324, P160, DOI 10.1136/bmj.324.7330.160
   Hunziker T, 2004, HAUTARZT, V55, P1077, DOI 10.1007/s00105-004-0830-4
   Jünger M, 2004, CURR MED RES OPIN, V20, P1613, DOI 10.1185/030079904X4086
   Kramer A, 2004, Z WUNDHEILUNG, V3, P110
   Lauer G, 2000, J INVEST DERMATOL, V115, P12, DOI 10.1046/j.1523-1747.2000.00036.x
   Moffatt CJ, 2003, WOUND REPAIR REGEN, V11, P166, DOI 10.1046/j.1524-475X.2003.11303.x
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Peters EJ, 2001, ARCH PHYS MED REHAB, V82, P721, DOI 10.1053/apmr.2001.23780
   Reimer K, 2000, DERMATOLOGY, V201, P235, DOI 10.1159/000018494
   Scherer LA, 2002, ARCH SURG-CHICAGO, V137, P930, DOI 10.1001/archsurg.137.8.930
   Sibbald R.G., 2003, Ostomy Wound Manage, V49, P23
   Singer AJ, 1999, NEW ENGL J MED, V341, P738, DOI 10.1056/NEJM199909023411006
   Valente JH, 2003, ANN EMERG MED, V41, P609, DOI 10.1067/mem.2003.137
   Vanscheidt W, 2001, EUR J DERMATOL, V11, P90
   Veves A, 2002, ARCH SURG-CHICAGO, V137, P822, DOI 10.1001/archsurg.137.7.822
   Vogt PM, 2001, WOUND REPAIR REGEN, V9, P116, DOI 10.1046/j.1524-475x.2001.00116.x
   Vogt T, 2002, HAUTARZT, V53, P561, DOI 10.1007/s00105-002-0412-2
   WINTER GD, 1962, NATURE, V193, P293, DOI 10.1038/193293a0
   WITTHOFF M, 2004, ZFW, V9
   Wollina U, 2000, J EUR ACAD DERMATOL, V14, P285, DOI 10.1046/j.1468-3083.2000.00105.x
   Zimny S, 2003, DIABETIC MED, V20, P622, DOI 10.1046/j.1464-5491.2003.01011.x
NR 40
TC 0
Z9 0
U1 0
U2 3
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 0017-8470
EI 1432-1173
J9 HAUTARZT
JI Hautarzt
PD MAY
PY 2005
VL 56
IS 5
BP 411
EP +
DI 10.1007/s00150-005-0932-7
PG 11
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 930EQ
UT WOS:000229399000005
DA 2026-07-24
ER

PT J
AU Tulimieri, MT
   Callas, PW
   D'Oria, M
   Bertges, DJ
AF Tulimieri, Maxwell T.
   Callas, Peter W.
   D'Oria, Mario
   Bertges, Daniel J.
TI Effectiveness of Closed Incision Negative Pressure Wound Therapy for
   Infrainguinal Bypass in the Vascular Quality Initiative
SO ANNALS OF VASCULAR SURGERY
LA English
DT Article
ID REVASCULARIZATION; COMPLICATIONS; TRIAL
AB Background: To analyze surgical site infections (SSIs) after infrainguinal bypass for standard dressings versus closed incision negative pressure wound therapy (ciNPWT) in the Society for Vascular Surgery's Vascular Quality Initiative (VQI). Methods: We retrospectively analyzed SSI after infrainguinal bypass procedures in the VQI from December 2019 to December 2021 comparing ciNPWT and standard dressings. The primary outcome of any superficial or deep wound infection at 30 days was analyzed in a subset of procedures with 30 -day follow-up data (cohort A, n = 1,575). Secondary outcomes including in -hospital SSI, return to the operating room (OR) for infection, and length of stay (LOS) were analyzed for all procedures (cohort B, n = 9,288). Outcomes were analyzed in propensitymatched cohorts. Results: Patients who received ciNPWT (n = 1,389) were more likely to be female (34% vs. 32%, P = 0.04) with a higher rate of smoking history (90% vs. 86%, P = 0.003), diabetes (54% vs. 50%, P = 0.007), obesity (34% vs. 26%, P < 0.001), prior peripheral vascular intervention (57% vs. 51%, P < 0.001), and to prosthetic conduit (55% vs. 48%, P < 0.001) compared to patients with standard dressings (n = 7,899). After propensity matching of cohort A (n = 1,256), the 30 -day SSI rate was 4% (12/341) in the ciNPWT and 6% (54/896) in the standard dressing group (P = 0.07, 95% CI 0.03-1.06). In the propensity -matched in -hospital cohort B (n = 5,435), SSI was 3% (35/1,371) in the ciNPWT group and 2% (95/4,064) in the standard dressing group (P = 0.66). There was no difference in the rate of return to the OR for infection, 1% (36/4,064) vs. 1% (19/1,371) (P = 0.13) or LOS, 9.0 vs. 9.0 days (P = 0.86) for the standard versus ciNPWT groups. Conclusions: In this analysis of the VQI registry, the use of ciNPWT after infrainguinal bypass did not result in a statistically significant decrease in 30 -day SSI. We recommend that surgeons consider the use of ciNPWT as part of a bundled process of care for high risk rather than all patients, as it may reduce SSI after infrainguinal bypass.
C1 [Tulimieri, Maxwell T.] Univ Vermont, Larner Coll Med, Burlington, VT USA.
   [Callas, Peter W.] Univ Vermont, Med Biostat, Burlington, VT USA.
   [D'Oria, Mario] Univ Hosp Trieste, Cardiovasc Dept, Div Vasc & Endovascular Surg, Trieste, Italy.
   [Bertges, Daniel J.] Univ Vermont, Div Vasc Surg, Med Ctr, Burlington, VT USA.
   [Bertges, Daniel J.] Univ Vermont, Div Vasc Surg, Med Ctr, 111 Colchester Ave,Smith 338, Burlington, VT 05401 USA.
C3 University of Vermont; University of Vermont; University of Trieste;
   University Trieste Hospital; University of Vermont; University of
   Vermont Medical Center; University of Vermont Medical Center; University
   of Vermont
RP Bertges, DJ (通讯作者)，Univ Vermont, Div Vasc Surg, Med Ctr, 111 Colchester Ave,Smith 338, Burlington, VT 05401 USA.
EM daniel.bertges@uvmhealth.org
RI D'Oria, Mario/AAF-5578-2020
CR A Novak, 2014, Open Orthop J, V8, P168, DOI 10.2174/1874325001408010168
   [Anonymous], 2020, SVS VQI Procedures Collected, The Vascular Quality Initia- tive.
   Antoniou GA, 2019, J VASC SURG, V70, P1700, DOI 10.1016/j.jvs.2019.01.083
   Bertges DJ, 2021, J VASC SURG, V74, P257, DOI 10.1016/j.jvs.2020.12.100
   Borgquist O, 2011, WOUND REPAIR REGEN, V19, P727, DOI 10.1111/j.1524-475X.2011.00741.x
   Engelhardt M, 2018, INT WOUND J, V15, P327, DOI 10.1111/iwj.12848
   Fernandez LG, 2019, CUREUS J MED SCIENCE, V11, DOI 10.7759/cureus.5183
   Frisbie JJ, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9217
   Glass GE, 2014, BJS-BRIT J SURG, V101, P1627, DOI 10.1002/bjs.9636
   Gombert A, 2020, VASCULAR, V28, P274, DOI 10.1177/1708538119890960
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Gurtner GC, 2008, NATURE, V453, P314, DOI 10.1038/nature07039
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   McGillicuddy EA, 2016, J VASC SURG, V64, P1780, DOI 10.1016/j.jvs.2016.05.068
   Meeker J, 2011, J ORTHOP TRAUMA, V25, P756, DOI 10.1097/BOT.0b013e318211363a
   Mirzaie AA, 2023, J VASC SURG, V77, P248, DOI 10.1016/j.jvs.2022.06.024
   Murphy P, 2015, TRIALS, V16, DOI 10.1186/s13063-015-1026-1
   Pherson MJ, 2022, J VASC SURG, V76, P1014, DOI 10.1016/j.jvs.2022.04.040
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Sabat J, 2016, J VASC SURG, V63, p94S, DOI 10.1016/j.jvs.2016.03.099
   Strobel RM, 2022, LANGENBECK ARCH SURG, V407, P819, DOI 10.1007/s00423-021-02346-y
   Svensson-Björk R, 2019, BJS-BRIT J SURG, V106, P310, DOI 10.1002/bjs.11100
   Wee IJY, 2019, EUR J VASC ENDOVASC, V58, P446, DOI 10.1016/j.ejvs.2018.12.021
   Willy C, 2017, INT WOUND J, V14, P385, DOI 10.1111/iwj.12612
NR 25
TC 2
Z9 2
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD MAY
PY 2024
VL 102
BP 47
EP 55
DI 10.1016/j.avsg.2023.11.050
EA FEB 2024
PG 9
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA NA6W9
UT WOS:001197767300001
PM 38307232
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Beckmann, NA
   Hanslmeier, MG
   Omlor, GW
   Feisst, M
   Maier, MW
   Lehner, B
AF Beckmann, Nicholas A.
   Hanslmeier, Maximilian G.
   Omlor, Georg W.
   Feisst, Manuel
   Maier, Michael W.
   Lehner, Burkhard
TI Is Negative Pressure Wound Therapy with Instillation Suitable for the
   Treatment of Acute Periprosthetic Hip Joint Infection?
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE hip; joint infection; prosthesis; arthroplasty; DAIR; debridement and
   implant retention; NPWTI; THA; negative pressure wound therapy
ID TOTAL KNEE ARTHROPLASTY; IMPLANT RETENTION; PROSTHESIS RETENTION;
   BACTERIAL BIOFILMS; FAILED IRRIGATION; DEBRIDEMENT; OUTCOMES;
   ANTIBIOTICS; REPLACEMENT; MANAGEMENT
AB Background: Periprosthetic joint infection (PJI) can be devastating for the patient and demanding for the surgeon. In acute PJI, attempts are made to retain the prosthesis by debridement of the infected tissue, targeted antibiotic therapy and an exchange of modular components with implant retention (DAIR). There has been sparse research with adjunctive negative pressure wound treatment with wound irrigation (NPWTI) on the treatment outcome. Questions/purposes: The goal was to assess the efficacy of our protocol of DAIR with adjunctive NPWTI in acute PJI and to reduce the need for later additional DAIR and Irrigation and Debridement (I and D). Patients and Methods: Our cohort of 30 patients (31 hips) with acute PJI was divided into two groups based on symptom presentation up to 6 weeks or >6 weeks from prior (index) surgery (acute early or acute late groups, respectively). All received DAIR with an exchange of modular components and NPWTI with polyhexanide instillation, with the goal of bacterial elimination and biofilm elimination. Postoperatively, the patients were followed up clinically and radiographically for a mean of 4.3 years. Results: Of the 31 PJI hips, 19 were early acute and 12 were late acute. In total, 21 hips had no evidence of residual infection, 10 required further surgical revision: 1 due to dislocation and 9 due to infection. Of these nine, seven had a removal of all the components and two were treated with irrigation and debridement (I and D), with the demise of one patient from pneumonia shortly after the procedure. The Kaplan-Meier 60-month revision free implant survival from infection was 73.2% (CI: 58.9-91.0%) and at the final follow up, the mean Harris Hip Score (HHS) was 81.1 +/- 11.8 and the mean WOMAC score was 33.3 +/- 20.1. Conclusions: Our results are in line with those reported in prior studies. However, the utility of our protocol is inconclusive and needs further evaluation based on our small cohort and the lack of a control group. Level of Evidence: IV.
C1 [Beckmann, Nicholas A.; Hanslmeier, Maximilian G.; Omlor, Georg W.; Lehner, Burkhard] Univ Hosp Heidelberg, Dept Orthopaed & Trauma Surg, Schlierbacher Landstr 200A, D-69118 Heidelberg, Germany.
   [Feisst, Manuel] Univ Hosp Heidelberg, Inst Med Biometr & Informat, Neuenheimer Feld 130-3, D-69120 Heidelberg, Germany.
   [Maier, Michael W.] Swabian Joint Ctr, Christoph Str 7, D-70178 Stuttgart, Germany.
C3 Ruprecht Karls University Heidelberg; Ruprecht Karls University
   Heidelberg
RP Beckmann, NA (通讯作者)，Univ Hosp Heidelberg, Dept Orthopaed & Trauma Surg, Schlierbacher Landstr 200A, D-69118 Heidelberg, Germany.
EM nicholas.beckmann@med.uni-heidelberg.de;
   Maximilian.Hanslmeier@med.uni-heidelberg.de;
   Georg.Omlor@med.uni-heidelberg.de; feisst@imbi.uni-heidelberg.de;
   maier@sgz-stuttgart.de; burkhard.lehner@med.uni-heidelberg.de
RI Beckmann, Nicholas/IYT-0829-2023
CR Aboltins C, 2013, INTERN MED J, V43, P810, DOI 10.1111/imj.12174
   [Anonymous], 2010, INFECTION, V37, P3
   [Anonymous], 2009, INFECTION, V37, P1
   Arnold WV, 2013, J BONE JOINT SURG AM, V95A, P2224
   Austria V., 2020, R FDN STAT COMP
   Azzam KA, 2010, J ARTHROPLASTY, V25, P1022, DOI 10.1016/j.arth.2010.01.104
   BELLAMY N, 1988, J RHEUMATOL, V15, P1833
   Bozic KJ, 2009, J BONE JOINT SURG AM, V91A, P128, DOI 10.2106/JBJS.H.00155
   Brandt CM, 1997, CLIN INFECT DIS, V24, P914, DOI 10.1093/clinids/24.5.914
   Brimmo O, 2016, J ARTHROPLASTY, V31, P461, DOI 10.1016/j.arth.2015.08.044
   Bryan AJ, 2017, J BONE JOINT SURG AM, V99, P2011, DOI [10.2106/JBJS.16.01103, 10.2106/jbjs.16.01103]
   Byren I, 2009, J ANTIMICROB CHEMOTH, V63, P1264, DOI 10.1093/jac/dkp107
   Costerton JW, 1999, SCIENCE, V284, P1318, DOI 10.1126/science.284.5418.1318
   Crockarell JR, 1998, J BONE JOINT SURG AM, V80A, P1306, DOI 10.2106/00004623-199809000-00009
   Davis JS, 2005, INTERN MED J, V35, pS79, DOI 10.1111/j.1444-0903.2005.00982.x
   Diaz-Ledezma C, 2013, CLIN ORTHOP RELAT R, V471, P2374, DOI 10.1007/s11999-013-2866-1
   Donlan RM, 2002, CLIN MICROBIOL REV, V15, P167, DOI 10.1128/CMR.15.2.167-193.2002
   Doyle D J., 2020, American Society of Anesthesiologists Classification
   Estes CS, 2010, CLIN ORTHOP RELAT R, V468, P2029, DOI 10.1007/s11999-010-1293-9
   Fehring TK, 2013, CLIN ORTHOP RELAT R, V471, P250, DOI 10.1007/s11999-012-2373-9
   Fink B, 2017, J ARTHROPLASTY, V32, P1255, DOI 10.1016/j.arth.2016.10.011
   Gardner J, 2011, CLIN ORTHOP RELAT R, V469, P970, DOI 10.1007/s11999-010-1417-2
   Gbejuade HO, 2015, ACTA ORTHOP, V86, P147, DOI 10.3109/17453674.2014.966290
   Goswami K, 2018, CURR REV MUSCULOSKE, V11, P428, DOI 10.1007/s12178-018-9513-0
   Grammatopoulos G, 2017, J ARTHROPLASTY, V32, P2248, DOI 10.1016/j.arth.2017.02.066
   Hackett DJ, 2015, J AM ACAD ORTHOP SUR, V23, pS1, DOI 10.5435/JAAOS-D-14-00394
   HARRIS WH, 1969, J BONE JOINT SURG AM, VA 51, P737, DOI 10.2106/00004623-196951040-00012
   Hirsiger S, 2019, J CLIN MED, V8, DOI 10.3390/jcm8020226
   Klouche S, 2011, ORTHOP TRAUMATOL-SUR, V97, P134, DOI 10.1016/j.otsr.2011.01.002
   Koyonos L, 2011, CLIN ORTHOP RELAT R, V469, P3043, DOI 10.1007/s11999-011-1910-2
   Krasowski G, 2021, MEMBRANES-BASEL, V11, DOI 10.3390/membranes11010062
   Kremers HM, 2015, J BONE JOINT SURG AM, V97A, P1386, DOI 10.2106/JBJS.N.01141
   Kuiper JWP, 2014, WORLD J ORTHOP, V5, P667, DOI 10.5312/wjo.v5.i5.667
   Kunutsor SK, 2018, J INFECTION, V77, P479, DOI 10.1016/j.jinf.2018.08.017
   Kurtz SM, 2012, J ARTHROPLASTY, V27, P61, DOI 10.1016/j.arth.2012.02.022
   Lehner B, 2020, ORTHOPADE, V49, P648, DOI 10.1007/s00132-020-03950-4
   Lehner B, 2011, INT ORTHOP, V35, P1415, DOI 10.1007/s00264-011-1274-y
   Lora-Tamayo J, 2013, CLIN INFECT DIS, V56, P182, DOI 10.1093/cid/cis746
   Löwik CAM, 2020, CLIN INFECT DIS, V71, P630, DOI 10.1093/cid/ciz867
   Maric S, 2007, PERIOD BIOL, V109, P115
   McConoughey SJ, 2014, FUTURE MICROBIOL, V9, P987, DOI [10.2217/FMB.14.64, 10.2217/fmb.14.64]
   McLawhorn Alexander S, 2016, Open Orthop J, V10, P615, DOI [10.2174/1874325001610010615, 10.2174/1874325001610010615]
   Moojen DJF, 2014, ACTA ORTHOP, V85, P383, DOI 10.3109/17453674.2014.927729
   Mooney JA, 2018, J ORTHOP RES, V36, P2331, DOI 10.1002/jor.24019
   Namba RS, 2005, J ARTHROPLASTY, V20, P46, DOI 10.1016/j.arth.2005.04.023
   Nodzo SR, 2017, J ARTHROPLASTY, V32, P2508, DOI 10.1016/j.arth.2017.03.026
   Osmon DR, 2013, CLIN INFECT DIS, V56, DOI [10.1093/cid/cis803, 10.1093/cid/cis966]
   Parvizi J, 2013, BONE JOINT J, V95B, P1450, DOI 10.1302/0301-620X.95B11.33135
   Parvizi J, 2018, J ARTHROPLASTY, V33, P1309, DOI 10.1016/j.arth.2018.02.078
   Parvizi J, 2011, CLIN ORTHOP RELAT R, V469, P2992, DOI 10.1007/s11999-011-2102-9
   Parvizi J, 2008, ACTA ORTHOP BELG, V74, P793
   Rodríguez D, 2010, CLIN MICROBIOL INFEC, V16, P1789, DOI 10.1111/j.1469-0691.2010.03157.x
   Romanò C, 2014, J KNEE SURG, V27, P267, DOI 10.1055/s-0034-1373736
   Romanò CL, 2012, HIP INT, V22, pS19, DOI 10.5301/HIP.2012.9566
   Sendi P, 2011, CLIN MICROBIOL INFEC, V17, P1098, DOI 10.1111/j.1469-0691.2011.03510.x
   Sherrell JC, 2011, CLIN ORTHOP RELAT R, V469, P18, DOI 10.1007/s11999-010-1434-1
   Sousa Ricardo, 2018, J Bone Jt Infect, V3, P108, DOI [10.7150/jbji.24285, 10.7150/jbji.24285]
   Sukeik M, 2012, CLIN ORTHOP RELAT R, V470, P3164, DOI 10.1007/s11999-012-2500-7
   TEGNER Y, 1985, CLIN ORTHOP RELAT R, P43
   Tornero E, 2016, J ANTIMICROB CHEMOTH, V71, P1395, DOI 10.1093/jac/dkv481
   Trampuz A, 2006, CURR OPIN INFECT DIS, V19, P349, DOI 10.1097/01.qco.0000235161.85925.e8
   Triantafyllopoulos GK, 2015, J ARTHROPLASTY, V30, P649, DOI 10.1016/j.arth.2014.10.026
   Tsang STJ, 2017, BONE JOINT J, V99B, P1458, DOI [10.1302/0301-620X.99B11.BJJ-2017-0088.R1, 10.1302/0301-620x.99b11.bjj-2017-0088.r1]
   Tsukayama DT, 1996, J BONE JOINT SURG AM, V78A, P512, DOI 10.2106/00004623-199604000-00005
   Van Kleunen JP, 2010, CLIN ORTHOP RELAT R, V468, P2024, DOI 10.1007/s11999-010-1291-y
   Veltman Ewout S, 2018, J Bone Jt Infect, V3, P5, DOI [10.7150/jbji.20259, 10.7150/jbji.20259]
   Westberg M, 2012, ACTA ORTHOP, V83, P227, DOI 10.3109/17453674.2012.678801
   Wu H, 2015, INT J ORAL SCI, V7, P1, DOI 10.1038/ijos.2014.65
   Zahiri CA, 1998, J ARTHROPLASTY, V13, P890, DOI 10.1016/S0883-5403(98)90195-4
   Zaruta DA, 2018, CURR REV MUSCULOSKE, V11, P347, DOI 10.1007/s12178-018-9497-9
   Zimmerli, 2000, Curr Infect Dis Rep, V2, P377, DOI 10.1007/s11908-000-0059-z
   Zmistowski B, 2013, J BONE JOINT SURG AM, V95A, P2177, DOI 10.2106/JBJS.L.00789
NR 72
TC 6
Z9 8
U1 0
U2 1
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD AUG
PY 2021
VL 10
IS 15
AR 3246
DI 10.3390/jcm10153246
PG 13
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA TW0FI
UT WOS:000682087100001
PM 34362030
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Niimi, Y
   Baba, K
   Tsuchida, M
   Takeda, A
AF Niimi, Yuta
   Baba, Kyoko
   Tsuchida, Masako
   Takeda, Akira
TI A Histological Evaluation of Artificial Dermal Scaffold Used in
   Micrograft Treatment: A Case Study of Micrograft and NPWT Performed on a
   Postoperative Ulcer Formation after Tumor Resection
SO MEDICINA-LITHUANIA
LA English
DT Article
DE micrograft; artificial dermis; negative pressure wound therapy; skin
   ulcer; histological evaluation
AB Background and Objectives: Wound healing (WH) is a complex natural process: the achieving of a proper WH with standard therapies sometimes is not fulfilled and it is often observed in aged and diabetic patients, leading to intractable ulcers. In recent years, autologous micrograft (AMG) therapies have become a new, effective, and affordable wound care strategy among both researchers and clinicians. In this study, a 72-year-old female patient underwent a combination of treatments using micrograft and negative pressure wound therapy (NPWT) on a postoperative skin ulcer after a benign tumor resection on the back with the aim to present an innovative method to treat skin ulceration using AMG combined with an artificial dermal scaffold and NPWT. Materials and Methods: A section of the artificial dermal scaffold, infused with micrografts, was sampled prior to transplant, and sections were collected postoperatively on days 3 and 7. Hematoxylin-eosin (HE) and immunohistochemical stains were employed for the evaluation of Cytokeratin AE1/AE3, desmin, and Factor VIII. Additionally, on postoperative day 3, NPWT dressing was evaluated using HE stains, as well. The resulting HE and immunostaining analysis revealed red blood cells and tissue fragments within the collagen layers of the artificial dermis prior to transplant. On postoperative day 3, collagen layers of the artificial dermis revealed red blood cells and neutrophils based on HE stains, and scattering of cytokeratin AE1/AE3-positive cells were detected by immunostaining. The HE stains on postoperative day 7 showed more red blood cells and neutrophils within the collagen layers of the artificial dermis than on day 3, an increase in cytokeratin AE1/AE3-positive cells, and tissue stained positively with desmin and Factor VIII. Results: Results suggest that the effects of both micrografts and migratory cells have likely accelerated the wound healing process. Furthermore, the NPWT dressing on day 3 showed almost no cells within the dressing. This indicated that restarting NPWT therapy immediately after micrograft transplant did not draw out cells within the scaffold. Conclusions: Micrograft treatment and NPWT may serve to be a useful combination therapy for complex processes of wound healing.
C1 [Niimi, Yuta; Baba, Kyoko; Tsuchida, Masako; Takeda, Akira] Kitasato Univ, Med Ctr, Dept Plast Surg, Saitama 3648501, Japan.
   [Niimi, Yuta; Baba, Kyoko; Tsuchida, Masako; Takeda, Akira] Kitasato Univ, Sch Med, Dept Plast & Aesthet Surg, Sagamihara, Kanagawa 2520373, Japan.
C3 Kitasato University; Kitasato University
RP Baba, K (通讯作者)，Kitasato Univ, Med Ctr, Dept Plast Surg, Saitama 3648501, Japan.; Baba, K (通讯作者)，Kitasato Univ, Sch Med, Dept Plast & Aesthet Surg, Sagamihara, Kanagawa 2520373, Japan.
EM y.niimi@kitasato-u.ac.jp; kyokobaba@med.kitasato-u.ac.jp;
   masako19@kitasato-u.ac.jp; takeda@kitasato-u.ac.jp
OI BABA, Kyoko/0000-0002-6069-7044; Niimi, Yuta/0000-0003-1458-4214
FU Grants-in-Aid for Scientific Research [20K09871] Funding Source: KAKEN
CR Andreone A., 2021, RECONSTRUCTION SCALP, P58
   [Anonymous], 1939, SURG GYNECOL OBSTET
   Astarita C, 2020, J INT MED RES, V48, DOI 10.1177/0300060520914794
   Balli M, 2020, CELL DEATH DIFFER, V27, P1520, DOI 10.1038/s41418-019-0433-3
   Biswas Atanu, 2010, J Diabetes Sci Technol, V4, P808
   CHICK LR, 1988, ANN PLAS SURG, V21, P358, DOI 10.1097/00000637-198810000-00011
   Converse JM, 1942, ANN SURG, V115, P321, DOI 10.1097/00000658-194203000-00001
   De Francesco F, 2017, STEM CELL REV REP, V13, P139, DOI 10.1007/s12015-016-9692-2
   Gabarro P, 1943, BMJ-BRIT MED J, V1943, P723, DOI 10.1136/bmj.1.4301.723
   Giaccone M., 2016, J STEM CELLS RES REV, V1, P1013
   Graziano A., 2014, ANN ORAL MAXILLOFAC, V17, P644
   Jimi S, 2020, MEDICINA-LITHUANIA, V56, DOI 10.3390/medicina56070321
   Jimi S, 2017, INT J MOL SCI, V18, DOI 10.3390/ijms18081675
   Reverdin J.L., 1869, Bull De La Societe'Imperiale Chirurgicale de Paris, P511
   Tresoldi MM, 2019, STEM CELLS INT, V2019, DOI 10.1155/2019/9843407
   Trovato L, 2016, Journal of Cell Science & Therapy, V07, DOI [10.4172/2157-7013.1000238, 10.4172/2157-7013.1000238, DOI 10.4172/2157-7013.1000238]
   Trovato L, 2015, J CELL PHYSIOL, V230, P2299, DOI 10.1002/jcp.24973
   Zhang M L, 1986, Burns Incl Therm Inj, V12, P540
   Zhang M L, 1986, Burns Incl Therm Inj, V12, P544
NR 19
TC 8
Z9 8
U1 0
U2 9
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
SN 1010-660X
EI 1648-9144
J9 MEDICINA-LITHUANIA
JI Med. Lith.
PD JAN
PY 2022
VL 58
IS 1
AR 73
DI 10.3390/medicina58010073
PG 11
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA YN5OE
UT WOS:000747307000001
PM 35056381
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kramer, A
   Dissemond, J
   Kim, S
   Willy, C
   Mayer, D
   Papke, R
   Tuchmann, F
   Assadian, O
AF Kramer, Axel
   Dissemond, Joachim
   Kim, Simon
   Willy, Christian
   Mayer, Dieter
   Papke, Roald
   Tuchmann, Felix
   Assadian, Ojan
TI Consensus on Wound Antisepsis: Update 2018
SO SKIN PHARMACOLOGY AND PHYSIOLOGY
LA English
DT Article
DE Wound antisepsis; Wounds-at-Risk Score; Antiseptics; Drug; Medical
   device; Octenidine; Polihexanide; Hypochlorite; Iodophors; Taurolidine;
   Silver ions; Acetic acid; Negative pressure wound therapy with the
   instillation of antiseptics; Physical body warm atmospheric plasma;
   Silver sulfadiazine; Dyes; Mercury compounds; Hydrogen peroxide
ID RESISTANT STAPHYLOCOCCUS-AUREUS; TISSUE-TOLERABLE PLASMA; SUPER-OXIDIZED
   SOLUTION; RANDOMIZED CONTROLLED-TRIAL; SURGICAL SITE INFECTIONS; VENOUS
   LEG ULCERS; PSEUDOMONAS-AERUGINOSA BIOFILM; ATMOSPHERIC-PRESSURE PLASMA;
   CADEXOMER-IODINE OINTMENT; ACETIC-ACID TREATMENT
AB Wound antisepsis has undergone a renaissance due to the introduction of highly effective wound-compatible antimicrobial agents and the spread of multidrug-resistant organisms (MDROs). However, a strict indication must be set for the application of these agents. An infected or critically colonized wound must be treated antiseptically. In addition, systemic antibiotic therapy is required in case the infection spreads. If applied preventively, the Wounds-at-Risk Score allows an assessment of the risk for infection and thus appropriateness of the indication. The content of this updated consensus recommendation still largely consists of discussing properties of octenidine dihydrochloride (OCT), poli-hexanide, and iodophores. The evaluations of hypochlorite, taurolidine, and silver ions have been updated. For critically colonized and infected chronic wounds as well as for burns, polihexanide is classified as the active agent of choice. The combination 0.1% OCT/phenoxyethanol (PE) solution is suitable for acute, contaminated, and traumatic wounds, including MRSA-colonized wounds due to its deep action. For chronic wounds, preparations with 0.05% OCT are preferable. For bite, stab/puncture, and gunshot wounds, polyvinylpyrrolidone (PVP)-iodine is the first choice, while polihexanide and hypochlorite are superior to PVP-iodine for the treatment of contaminated acute and chronic wounds. For the decolonization of wounds colonized or infected with MDROs, the combination of OCT/PE is preferred. For peritoneal rinsing or rinsing of other cavities with a lack of drainage potential as well as the risk of central nervous system exposure, hypochlorite is the superior active agent. Silver-sulfadiazine is classified as dispensable, while dyes, organic mercury compounds, and hydrogen peroxide alone are classified as obsolete. As promising prospects, acetic acid, the combination of negative pressure wound therapy with the instillation of antiseptics (NPWTi), and cold atmospheric plasma are also subjects of this assessment. (C) 2017 S. Karger AG, Basel
C1 [Kramer, Axel; Papke, Roald] Univ Med Greifswald, Inst Hyg & Environm Med, Greifswald, Germany.
   [Kim, Simon] Univ Med Greifswald, Dept Trauma Reconstruct Surg & Rehabil Med, Greifswald, Germany.
   [Dissemond, Joachim] Univ Hosp Essen, Dept Dermatol Venerol & Allergol, Hufelandstr 55, DE-45147 Essen, Germany.
   [Willy, Christian] Bundeswehr Hosp, Dept Trauma Surg Orthoped Reconstruct Plast & Han, Berlin, Germany.
   [Mayer, Dieter] Kantonsspital Freiburg, Dept Surg, Freiburg, Germany.
   [Tuchmann, Felix] Med Univ Vienna, Vienna Gen Hosp, Dept Dermatol, Vienna, Austria.
   [Assadian, Ojan] Med Univ Vienna, Vienna Gen Hosp, Dept Infect Control & Hosp Epidemiol, Vienna, Austria.
C3 Universitat Greifswald; Greifswald Medical School; Universitat
   Greifswald; Greifswald Medical School; University of Duisburg Essen;
   Medical University of Vienna; Medical University of Vienna
RP Dissemond, J (通讯作者)，Univ Hosp Essen, Dept Dermatol Venerol & Allergol, Hufelandstr 55, DE-45147 Essen, Germany.
EM joachim.dissemond@uk-essen.de
RI ; Assadian, Ojan/GVT-8804-2022; Dissemond, Joachim/AFG-0691-2022; Mayer,
   Dieter/E-7617-2011
OI Kim, Simon/0000-0002-7455-7421; Mayer, Dieter/0000-0001-5933-7749
FU Antiseptika chem.pharm. GmbH; B. Braun Melsungen AG; Bode/Paul Hartmann
   AG; Lohmann and Rauscher; Maquet GmbH; Schulke and Mayr GmbH; SERAG -
   WIESSNER GmbH and Co. KG; Oculus; Ethicon; 3M Healthcare; Acelity; B.
   Braun; Coloplast; Convatec; Draco; Engelhard; Flen Pharma; Lohmann
   Rauscher; Molnlycke; Serag-Wiesner; Urgo
FX Axel Kramer discloses that in the past he has received research support,
   lecture fees, and travel-cost reimbursements from the following
   companies: Antiseptika chem.pharm. GmbH, B. Braun Melsungen AG,
   Bode/Paul Hartmann AG, Lohmann and Rauscher, Maquet GmbH, Schulke and
   Mayr GmbH, SERAG - WIESSNER GmbH and Co. KG, Oculus, Ethicon, and 3M
   Healthcare. However, the present publication is not connected with
   financial interests.Joachim Dissemond discloses that in the past he has
   received research support, lecture fees, and travel-cost reimbursements
   from the following companies: Acelity, B. Braun, Coloplast, Convatec,
   Draco, Engelhard, Flen Pharma, Lohmann & Rauscher, Molnlycke,
   Serag-Wiesner, and Urgo.
CR Abhyankar Suhas V, 2009, J Indian Med Assoc, V107, P904
   Acton C, 2011, BEST PRACTICE STATEM
   Aggarwal R, 2010, INDIAN J PATHOL MICR, V53, P757, DOI 10.4103/0377-4929.72076
   Akkus A, 2006, SURG TODAY, V36, P436, DOI 10.1007/s00595-005-3155-8
   Allie DE, 2006, WOUNDS, P3
   Altamirano MA, 2005, TEX SURG SOC C SAN A
   Andrews JM, 2001, J ANTIMICROB CHEMOTH, V48, P5, DOI 10.1093/jac/48.suppl_1.5
   Angel DE, 2008, WOUND PRACT RES, V16, P6
   [Anonymous], ANTISEPTICS SURG
   [Anonymous], 2016, B ARZNEIMITTELSI JUN
   Aragón-Sánchez J, 2013, INT J LOW EXTR WOUND, V12, P130, DOI 10.1177/1534734613476710
   Assadian O, BR J DERM IN PRESS
   AWMF, 2014, ANF HYG BEI CHRON SE
   BAKER DM, 1994, BRIT J SURG, V81, P1054, DOI 10.1002/bjs.1800810743
   Barrett S, 2010, WOUNDS UK, V6, P1
   Basavraj Nagoba Basavraj Nagoba, 2008, European Journal of General Medicine, V5, P104
   BEDROSIAN I, 1991, CYTOKINE, V3, P568, DOI 10.1016/1043-4666(91)90483-T
   Beldame J, 2012, ORTHOP TRAUMATOL-SUR, V98, P432, DOI 10.1016/j.otsr.2011.10.015
   Bellingeri A, 2016, J WOUND CARE, V25, P160, DOI 10.12968/jowc.2016.25.3.160
   Below H, 2017, BRIT J ORAL MAX SURG, V55, P150, DOI 10.1016/j.bjoms.2016.10.007
   Below H, 2007, GMS HYG INFECT CONTR, V2
   Bender C, 2012, 4 INT C PLASM MED
   Bender Claudia P., 2012, NATO Advanced Research Workshop on Plasma for Bio-Decontamination, Medicine and Food Security. Proceedings, P321, DOI 10.1007/978-94-007-2852-3_25
   Bender C, 2016, TIERAERZTL UMSCHAU, V71, P262
   Bender C, 2011, TOXICOL IN VITRO, V25, P530, DOI 10.1016/j.tiv.2010.11.012
   Blangy H, 2002, THERAPIE, V57, P307
   Bolton LL, 1985, MODELS DERMATOLOGY, V2, P145
   Bongiovanni CM., 2006, Diabetic Microvasc Compl Today, P11
   Bowler PG, 2001, CLIN MICROBIOL REV, V14, P244, DOI 10.1128/CMR.14.2.244-269.2001
   Boyd LB, 2009, ANTIMICROB AGENTS CH, V53, P229, DOI 10.1128/AAC.00722-08
   Braun M, 2013, Wounds UK, V9, P1
   Braun M., 2014, WOUNDS K, V10, P89
   BRIEDIS DJ, 1976, ANTIMICROB AGENTS CH, V10, P592, DOI 10.1128/AAC.10.4.592
   Brudzynski K, 2006, CAN J MICROBIOL, V52, P1228, DOI 10.1139/W06-086
   Butcher Martyn, 2012, Br J Nurs, V21, pS18
   Calow T, 2009, J DTSCH DERMATOL GES, V7, P759, DOI 10.1111/j.1610-0387.2009.07035.x
   Campbell N, 2013, J WOUND CARE, V22, P401, DOI 10.12968/jowc.2013.22.8.401
   Cantoni O, 1989, Ann Ist Super Sanita, V25, P69
   Capriotti K, 2012, DERMATOL ONLINE J, V18, P11
   Carpenter S, 2016, WOUNDS, V28, P1
   Cazzaniga A, 2002, WOUNDS, V14, P169
   Ceviker K, 2015, J WOUND CARE, V24, P582, DOI 10.12968/jowc.2015.24.12.582
   Chamanga ET, 2015, BR J NURS, V24, P30
   CHHABRA RS, 1991, FOOD CHEM TOXICOL, V29, P119, DOI 10.1016/0278-6915(91)90166-5
   Chindera K, 2016, SCI REP-UK, V6, DOI 10.1038/srep23121
   Cookson BD, 1998, J ANTIMICROB CHEMOTH, V41, P11, DOI 10.1093/jac/41.1.11
   Costa Sofia Santos, 2013, Open Microbiol J, V7, P59, DOI 10.2174/1874285801307010059
   Crabtree TD, 2001, DISINFECTION STERILI, P919
   Creppy EE, 2014, INT J ENV RES PUB HE, V11, P8069, DOI 10.3390/ijerph110808069
   Creytens K, 2014, CONTACT DERMATITIS, V71, P307, DOI 10.1111/cod.12279
   Cutting K, 2012, USE CLEANSING SOLUTI, V8, P130
   Cutting KF, 2010, BR J NURS, V19, P1
   D'Atanasio N, 2015, WOUNDS, V27, P265
   Daeschlein G, 2007, SKIN PHARMACOL PHYS, V20, P292, DOI 10.1159/000107577
   Dalla Paola L, 2005, J WOUND HEALING, V2, P201
   Davis K, 2013, WOUND REPAIR REGEN, V21, P869, DOI 10.1111/wrr.12104
   Davis S, 2002, WOUNDS, V14, P252
   Dissemond J, 2011, SKIN PHARMACOL PHYS, V24, P245, DOI 10.1159/000327210
   Dissemond J, 2003, HAUTARZT, V54, P959, DOI 10.1007/s00105-003-0554-x
   Dissemond J, 2017, J DTSCH DERMATOL GES, V15, P524, DOI 10.1111/ddg.13233
   Drosou A, 2003, WOUNDS, V15, P149
   Durante CM, 2014, MINERVA CHIR, V69, P283
   Eberlein T, 2012, J WOUND CARE, V21, P12, DOI 10.12968/jowc.2012.21.1.12
   Eberlein T, 2010, SKIN PHARMACOL PHYS, V23, P45, DOI 10.1159/000318267
   Eberlein T, 2014, INT J LOW EXTR WOUND, V10, P1
   Ebert M, 2011, SKIN PHARMACOL PHYS, V24, P337, DOI 10.1159/000330761
   Eisenbeiss W, 2012, INT J BURNS TRAUMA, V2, P71
   Eisenbeiss W, 2006, GMS HYG INFECT CONTR, V1
   Velazquez-Meza ME, 2015, MICROB DRUG RESIST, V21, P367, DOI 10.1089/mdr.2014.0266
   Fabry W, 2013, J GLOB ANTIMICROB RE, V1, P195, DOI 10.1016/j.jgar.2013.05.007
   Fabry W, 2014, J HOSP INFECT, V86, P68, DOI 10.1016/j.jhin.2013.10.002
   Fabry W, 2006, INT J HYG ENVIR HEAL, V209, P567, DOI 10.1016/j.ijheh.2006.03.008
   Fabry WHK, 2014, MICROB DRUG RESIST, V20, P138, DOI 10.1089/mdr.2013.0113
   FDA Drug Safety Communication, 2017, FDA WARNS RAR SER AL
   Fisher NM, 2003, J AM ACAD DERMATOL, V49, P730, DOI 10.1067/S0190-9622(02)61574-9
   Fitzgerald DJ, 2017, WOUND REPAIR REGEN, V25, P13, DOI 10.1111/wrr.12497
   Fleischmann W, 1998, UNFALLCHIRURG, V101, P649, DOI 10.1007/s001130050318
   Fleischmann W, 2006, GMS HYG INFECT CONTR, V1
   Forstner C, 2013, INT J MOL SCI, V14, P10582, DOI 10.3390/ijms140510582
   Freise J, 2008, J EUR ACAD DERMATOL, V22, P1203, DOI 10.1111/j.1468-3083.2008.02775.x
   Fricke K, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0042539
   Gallieni M, 2011, CLIN NEPHROL, V75, P70, DOI 10.2379/CNP75070
   Garg P, 2013, Arch Int Surg, V3, DOI DOI 10.4103/2278-9596.117121
   Gaspard F, 2013, WOUNDS, V25, P178
   Gentile A, 2012, BMC CLIN PATHOL, V12, DOI 10.1186/1472-6890-12-17
   Gerber V, 2006, GMS HYG INFECT CONTR, V1
   Gilliver S, 2009, J WOUND CARE, V11, P9
   Goertz O, 2011, ANN PLAS SURG, V67, P407, DOI 10.1097/SAP.0b013e318209a5fc
   Good H, 1979, CHARAKTERISIERUNG DE, P87
   Goss SG, 2012, AM COLL CLIN WOUND S, V4, P74
   GRUBER RP, 1975, PLAST RECONSTR SURG, V55, P472, DOI 10.1097/00006534-197555040-00013
   Gulati S, 2014, INDIAN J SURG, V76, P193, DOI 10.1007/s12262-012-0682-6
   Gutiérrez AA, 2006, WOUNDS, P7
   Habild G, 2006, GMS HYG INFECT CONTR, V1
   Hadi SF, 2007, JCPSP-J COLL PHYSICI, V17, P740, DOI 12.2007/JCPSP.740743
   Hämmerle G, 2016, INT WOUND J, V13, P182, DOI 10.1111/iwj.12250
   Hagelstein S.M., 2013, WOUNDS UK, V9, P84
   Halstead FD, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0136190
   Hammann A, 2010, SKIN PHARMACOL PHYS, V23, P328, DOI 10.1159/000314724
   Hansmann F, 2005, OPHTHALMOLOGE, V102, P1043, DOI 10.1007/s00347-004-1120-3
   Hansmann F, 2004, OPHTHALMOLOGE, V101, P377, DOI 10.1007/s00347-003-0933-9
   HANSSON C, 1995, ACTA DERM-VENEREOL, V75, P31
   Harati K, 2015, ANN BURNS FIRE DISAS, V27, P292
   Harnoss JC, WOUND REPAI IN PRESS
   HASEGAWA R, 1986, FOOD CHEM TOXICOL, V24, P1295, DOI 10.1016/0278-6915(86)90061-X
   Hentzer M, 2002, MICROBIOL-SGM, V148, P87, DOI 10.1099/00221287-148-1-87
   Hessam S, 2016, SKIN PHARMACOL PHYS, V29, P161, DOI 10.1159/000446812
   Hetem DJ, 2013, J HOSP INFECT, V85, P249, DOI 10.1016/j.jhin.2013.09.006
   Heuer H, 2007, ENVIRON MICROBIOL, V9, P657, DOI 10.1111/j.1462-2920.2006.01185.x
   Hierholzer G, 1984, PVP IOD OPERATIVEN M
   Hinz P, 2011, GYNAKOL PRAX, V35, P711
   Hoerauf H, 2013, KLIN MONATSBL AUGENH, V230, P1157, DOI 10.1055/s-0033-1351015
   Honing HJ, 2012, HYGMED, V37, P360
   Horton JW, 2003, TOXICOLOGY, V189, P75, DOI 10.1016/S0300-483X(03)00154-9
   Huang CY, 2014, CURR PROB SURG, V51, P301, DOI 10.1067/j.cpsurg.2014.04.001
   Hubner Nils-Olaf, 2009, Med Monatsschr Pharm, V32, P87
   Hubner-Muller C, 2000, Z WUNDBEHANDL, V12, P7
   Hübner NO, 2010, SKIN PHARMACOL PHYS, V23, P17, DOI 10.1159/000318264
   Hübner NO, 2010, SKIN PHARMACOL PHYS, V23, P28, DOI 10.1159/000318265
   Hübner NO, 2010, SKIN PHARMACOL PHYS, V23, P244, DOI 10.1159/000314699
   Hübner NO, 2007, GMS HYG INFECT CONTR, V2
   Hunt S, 2016, J WOUND CARE, V25, pS22, DOI 10.12968/jowc.2016.25.Sup3.S22
   Inagaki H, 2011, LAB ANIM-UK, V45, P283, DOI 10.1258/la.2011.010122
   Inoue Y, 1997, ARTIF ORGANS, V21, P28
   Isbary G, 2010, BRIT J DERMATOL, V163, P78, DOI 10.1111/j.1365-2133.2010.09744.x
   Jahn B, 2016, ANTIMICROB RESIST IN, V5, DOI 10.1186/s13756-016-0124-5
   Jeong HS, 2015, ARCH PLAST SURG-APS, V42, P59, DOI 10.5999/aps.2015.42.1.59
   Juma IM, 2007, J Techniques, V20, P73
   Junka A, 2014, INT WOUND J, V11, P730, DOI 10.1111/iwj.12057
   Kaehn K, 2009, J Wound Care, V18, P229
   Kamaruzzaman NF, 2016, J ANTIMICROB CHEMOTH, V71, P1252, DOI 10.1093/jac/dkv474
   Kampf Gunter, 2004, Ann Clin Microbiol Antimicrob, V3, P9, DOI 10.1186/1476-0711-3-9
   Kapur V, 2011, INDIAN J SURG, V73, P48, DOI 10.1007/s12262-010-0189-y
   KAUFFMAN CA, 1993, AM J MED, V94, P371, DOI 10.1016/0002-9343(93)90147-H
   Kautz O, 2010, ALLERGY, V65, P1068, DOI 10.1111/j.1398-9995.2009.02299.x
   Kim PJ, 2015, PLAST RECONSTR SURG, V136, p657E, DOI 10.1097/PRS.0000000000001709
   Kim PJ, 2014, PLAST RECONSTR SURG, V133, P709, DOI 10.1097/01.prs.0000438060.46290.7a
   Kim PJ, 2013, PLAST RECONSTR SURG, V132, P1569, DOI 10.1097/PRS.0b013e3182a80586
   Kim PJ, 2015, WOUNDS, V27, P2
   Kirker KR, 2009, WOUNDS, V21, P229
   Klasinc R, 2017, INT WOUND J
   Klein D, 2013, WEHRMED WEHRPHARM, V1, P52
   Kluge S, 2016, PLOS ONE, V11, DOI 10.1371/journal.pone.0160667
   Koban I, 2011, J CLIN PERIODONTOL, V38, P956, DOI 10.1111/j.1600-051X.2011.01740.x
   Koburger T, 2010, J ANTIMICROB CHEMOTH, V65, P1712, DOI 10.1093/jac/dkq212
   Koburger T, 2007, GMS HYG INFECT CONTR, V2
   Konig B, 1997, DERMATOLOGY, V195, P42, DOI 10.1159/000246029
   Konig B, 1997, DEUT MED WOCHENSCHR, V122, P141
   Kopmann C, 2013, FEMS MICROBIOL ECOL, V83, P125, DOI 10.1111/j.1574-6941.2012.01458.x
   Kramer A, 1998, CHIRURG, V69, P840, DOI 10.1007/s001040050498
   Kramer A, 2006, INT J CLIN PHARM TH, V44, P677
   Kramer A, 2013, CLIN PLASMA MED, V1, P11, DOI 10.1016/j.cpme.2013.03.002
   Kramer A, 2004, SKIN PHARMACOL PHYS, V17, P141, DOI 10.1159/000077241
   KRAMER A, 1987, Zeitschrift fuer die Gesamte Hygiene und ihre Grenzgebiete, V33, P610
   Kramer A, 2010, SKIN PHARMACOL PHYS, V23, P1, DOI 10.1159/000318899
   Kramer A, 1997, OPHTHALMOLOGICA, V211, P68, DOI 10.1159/000310889
   Kramer A, 2017, COMPREHENSIVE CLIN P
   Kramer A, 2004, Z WUNDHEILUNG, V3, P110
   Kramer A., 2008, WALLHAU ERS PRAXIS S, P713
   Kramer A, 1987, HDB ANTISEPTIK, VII, P447
   Kramer A, 2014, ENTZUNDLICHE AUGENER, P23
   Kramer A, 2017, WUNDMANAGEMENT, V11, P32
   Kramer A, 2008, WALLHAUSSERS PRAXIS, P592
   Kramer A, 2008, Wallhaussers Praxis der Sterilisation, Antiseptik und Konservierung: Qualitatssicherung der Hygiene in Industrie, Pharmazie und Medizin
   Kramer A, 2008, WALLHAUSSERS PRAXIS, P823
   Kramer A, J WOUND CAR IN PRESS
   Kramer A, 2009, GMS KRANKENHAUSHYG I, V4
   Kramer A, 2015, PLASMA PROCESS POLYM, V12, P1410, DOI 10.1002/ppap.201500170
   Kramer Axel, 2010, GMS Krankenhhyg Interdiszip, V5, DOI 10.3205/dgkh000155
   Kramer A, 2008, GMS HYG INFECT CONTR, V3
   Krasowski G, 2014, EWMA J, V14, P7
   Krasowski G, 2015, WOUND REPAIR REGEN, V23, P525, DOI 10.1111/wrr.12301
   Krzeminski M, 2010, ADV CLIN EXP MED, V19, P631
   Kubota A, 2009, SURG TODAY, V39, P514, DOI 10.1007/s00595-008-3914-4
   Küster I, 2016, EUR ARCH OTO-RHINO-L, V273, P1951, DOI 10.1007/s00405-015-3739-x
   KUROKAWA Y, 1986, ENVIRON HEALTH PERSP, V69, P221, DOI 10.2307/3430390
   Lademann J, 2012, SKIN PHARMACOL PHYS, V25, P100, DOI 10.1159/000335558
   Lademann O, 2011, SKIN PHARMACOL PHYS, V24, P284, DOI 10.1159/000329913
   Lamme EN, 1998, ARCH DERMATOL RES, V290, P18, DOI 10.1007/s004030050271
   Landa-Solis C, 2005, J HOSP INFECT, V61, P291, DOI 10.1016/j.jhin.2005.04.021
   Langer S, 2006, EUR SURG RES, V38, P27, DOI 10.1159/000091524
   Langer S, 2004, EUR J MED RES, V9, P449
   Laroussi M., 2012, PLASMA MED APPL LOW
   Lee CK, 2012, CLIN ORTHOP RELAT R, V470, P610, DOI 10.1007/s11999-011-1990-z
   Lehner B, 2011, INT ORTHOP, V35, P1415, DOI 10.1007/s00264-011-1274-y
   Lenselink E, 2011, J WOUND CARE, V20, P534, DOI 10.12968/jowc.2011.20.11.534
   Li SH, 2015, INT J CLIN EXP MED, V8, P14863
   LINEAWEAVER W, 1985, ARCH SURG-CHICAGO, V120, P267
   López-Rojas R, 2017, ENFERM INFEC MICR CL, V35, P12, DOI [10.1016/j.eimce.2017.01.004, 10.1016/j.eimc.2016.02.008]
   Madhusudhan VL, 2016, INT WOUND J, V13, P1129, DOI 10.1111/iwj.12428
   Maitre S, 2002, ANN DERMATOL VENER, V129, P217
   Marquardt C, 2014, COLOPROCTOLOGY, V36, P364, DOI 10.1007/s00053-014-0478-1
   Marsch G, 2014, EUROPACE, V16, P604, DOI 10.1093/europace/eut222
   Martinez-De Jesus Fermin R, 2007, Int Wound J, V4, P353
   Matiasek J, 2015, J WOUND CARE, V24, pS8, DOI 10.12968/jowc.2015.24.Sup6.S8
   Matiasek J, 2014, J WOUND CARE, V23, P590, DOI 10.12968/jowc.2014.23.11.590
   Matiasek J, 2015, GER MED SCI, DOI [10.3205/15dgpraec048, DOI 10.3205/15DGPRAEC048]
   Matthes R, 2016, SKIN PHARMACOL PHYS, V29, P83, DOI 10.1159/000443210
   MAYER KH, 1986, AM J MED, V80, P56, DOI 10.1016/0002-9343(86)90480-8
   Mayr-Kanhäuser S, 2008, ACTA DERMATOVEN ALP, V17, P139
   MCKENNA PJ, 1991, ANN PLAS SURG, V27, P265, DOI 10.1097/00000637-199109000-00011
   Medina-Tamayo J, 2007, INT IMMUNOPHARMACOL, V7, P1013, DOI 10.1016/j.intimp.2007.03.005
   Mendes J, 2014, EWMA
   Menke H, 2001, AKT TRAUMOTOL, V31, P211, DOI DOI 10.1055/S-2001-17686
   MERTZ PM, 1994, WOUNDS, V6, P184
   Middleton AM, 2000, J HOSP INFECT, V45, P278, DOI 10.1053/jhin.2000.0772
   MILNER SM, 1992, LANCET, V340, P61, DOI 10.1016/0140-6736(92)92483-V
   Moore Keith., 2007, Wounds UK, V3, P96
   Motta Glenda J, 2004, Ostomy Wound Manage, V50, P48
   Muangman P, 2011, INT J MOL SCI, V12, P5031, DOI 10.3390/ijms12085031
   Müller G, 2014, SKIN PHARMACOL PHYS, V27, P1, DOI 10.1159/000350172
   Müeller G, 2008, J ANTIMICROB CHEMOTH, V61, P1281, DOI 10.1093/jac/dkn125
   Mueller SW, 2008, AM J INFECT CONTROL, V36, P651, DOI 10.1016/j.ajic.2007.12.005
   Mueller TC, 2015, LANGENBECK ARCH SURG, V400, P167, DOI 10.1007/s00423-015-1279-x
   Mulder GD, 2007, WOUNDS, V19, P173
   Müller G, 2006, DERMATOLOGY, V212, P94, DOI 10.1159/000090103
   Müller G, 2005, J ORTHOP RES, V23, P127, DOI 10.1016/j.orthres.2004.06.003
   Müller G, 2007, GMS HYG INFECT CONTR, V2
   Nagoba BS, 2013, J INFECT PUBLIC HEAL, V6, P410, DOI 10.1016/j.jiph.2013.05.005
   Nagoba BS, 2015, WOUNDS, V27, P5
   Nanashima Atsushi, 2001, Acta Medica Nagasakiensia, V46, P33
   Napavichayanun S, 2016, ARCH DERMATOL RES, V308, P123, DOI 10.1007/s00403-016-1621-3
   NEU HC, 1978, ANTIMICROB AGENTS CH, V13, P657, DOI 10.1128/AAC.13.4.657
   Nherera LM, 2016, OSTOMY WOUND MANAG, V62, P26
   Noda Y, 2009, INT J PHARMACEUT, V372, P85, DOI 10.1016/j.ijpharm.2009.01.007
   Norman G, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011586
   O'Meara S, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003557.pub5
   Ohno H, 2000, SURG TODAY, V30, P1055, DOI 10.1007/s005950070035
   Olivieri J, 1998, SCHWEIZ MED WSCHR, V128, P1508
   Pandey PK, 2011, INT J BIOL MED RES, V2, P965
   Partecke LI, 2012, BMC CANCER, V12, DOI 10.1186/1471-2407-12-473
   Perez R, 2010, WUND MANAG, V4, P44
   PHILLIPS I, 1968, LANCET, V1, P11
   Phillips PL, 2015, INT WOUND J, V12, P469, DOI 10.1111/iwj.12142
   Piaggesi A, 2010, INT J LOW EXTR WOUND, V9, P10, DOI 10.1177/1534734610361945
   Piatkowski A, 2011, BURNS, V37, P800, DOI 10.1016/j.burns.2011.01.027
   Pitten FA, 2003, J HOSP INFECT, V55, P108, DOI 10.1016/S0195-6701(03)00260-3
   Poole K, 2007, ANN MED, V39, P162, DOI 10.1080/07853890701195262
   Radu CA, 2011, BURNS, V37, P294, DOI 10.1016/j.burns.2010.07.001
   Reimer K, 2000, DERMATOLOGY, V201, P235, DOI 10.1159/000018494
   Reitsma AM, 2001, EFFECTIVENESS NEW AN, P1
   Richter C, 2016, SKIN PHARMACOL PHYS, V29, P1, DOI 10.1159/000439439
   Robert LW, 2009, WOUNDS, V21, P1
   RODE H, 1989, ANTIMICROB AGENTS CH, V33, P1358, DOI 10.1128/AAC.33.8.1358
   Romanelli M, 2010, SKIN PHARMACOL PHYS, V23, P41, DOI 10.1159/000318266
   Rosman C, 1996, EUR SURG RES, V28, P351, DOI 10.1159/000129476
   Roth B, 2017, J WOUND CARE, V26, P79, DOI 10.12968/jowc.2017.26.3.79
   Roth B, 2010, SKIN PHARMACOL PHYS, V23, P4, DOI 10.1159/000318236
   Roth B, 2009, GMS HYG INFECT CONTR, V4
   Roth C, 2010, SKIN PHARMACOL PHYS, V23, P35, DOI 10.1159/000319602
   Rothe K, 2015, DTSCH ARZTEBL INT, V112, P433, DOI 10.3238/arztebl.2015.0433
   Ryssel H, 2009, BURNS, V35, P695, DOI 10.1016/j.burns.2008.11.009
   Salati S., 2008, IJS, V20, P1, DOI [10.5580/b3b, DOI 10.5580/B3B]
   Santos Oliveira AD, 2007, REV LAT-AM ENFERM, V15, P671, DOI 10.1590/S0104-11692007000400023
   Schedler K, 2017, BMC INFECT DIS, V17, DOI 10.1186/s12879-017-2220-4
   SCHLUTER B, 1990, THORAC CARDIOV SURG, V38, P339, DOI 10.1055/s-2007-1014046
   Schneider A, 2005, PEDIATR SURG INT, V21, P445, DOI 10.1007/s00383-005-1428-3
   Schnuch A, 2007, CONTACT DERMATITIS, V56, P235, DOI 10.1111/j.1600-0536.2007.01089.x
   SchrOder MA, 2014, UGESKRIFT LAEGER, V176, pV02120094
   Sekiya S, 1997, ARTIF ORGANS, V21, P32
   Shah C., 2007, MANAG INFECT CONTROL, V7, P26
   Shimizu T, 2011, NEW J PHYS, V13, DOI 10.1088/1367-2630/13/2/023026
   Sibbald RG, 2011, ADV SKIN WOUND CARE, V24, P78, DOI 10.1097/01.ASW.0000394027.82702.16
   Siemers F, 52 C DGH
   Silver S, 2003, FEMS MICROBIOL REV, V27, P341, DOI 10.1016/S0168-6445(03)00047-0
   Simor AE, 2007, ANTIMICROB AGENTS CH, V51, P3880, DOI 10.1128/AAC.00846-07
   Simpson JM, 2008, AM J VET RES, V69, P1210, DOI 10.2460/ajvr.69.9.1210
   Singh S, 2014, J EVOL MED DENT SCI-, V3, P6233, DOI 10.14260/jemds/2014/2728
   Skripitz R, 1994, HYG MED, V17, P19
   Sloss J M, 1993, J R Army Med Corps, V139, P49
   Sopata M, 2008, J Wound Care, V17, P24
   Sopata M, 2013, POSTEP DERM ALERGOL, V30, P237, DOI 10.5114/pdia.2013.37034
   Stahl J, 2011, BMC VET RES, V7, DOI 10.1186/1746-6148-7-44
   Stelzner A, 1984, HDB ANTISEPTIK, P160
   Storm-Versloot MN, 2010, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006478.pub2
   Swan J, 2011, WOUNDS UK, V7, P17
   Tam VH, 2006, ANTIMICROB AGENTS CH, V50, P2626, DOI 10.1128/AAC.01165-05
   Tanaka H, 1996, J HOSP INFECT, V34, P43, DOI 10.1016/S0195-6701(96)90124-3
   Tata MD, 2009, ANN THORAC SURG, V87, P1613, DOI 10.1016/j.athoracsur.2008.10.019
   Taylor K, 1916, J AMER MED ASSOC, V67, P1598
   THEN RL, 1992, J CHEMOTHERAPY, V4, P67
   Thomson P.D., 2000, Ostomy Wound Manage, V46, P77
   Thorn RMS, 2012, EUR J CLIN MICROBIOL, V31, P641, DOI 10.1007/s10096-011-1369-9
   Timmers MS, 2009, WOUND REPAIR REGEN, V17, P278, DOI 10.1111/j.1524-475X.2009.00458.x
   Timmers MS, 2005, ANN PLAS SURG, V55, P665, DOI 10.1097/01.sap.0000187182.90907.3d
   Tuncel U, 2013, INT WOUND J, V10, P152, DOI 10.1111/j.1742-481X.2012.00955.x
   Ulrich C, 2015, J WOUND CARE, V24, P196, DOI 10.12968/jowc.2015.24.5.196
   Upton A, 2003, J ANTIMICROB CHEMOTH, V51, P613, DOI 10.1093/jac/dkg127
   Urbach M, 2013, WUNDMANAGEMENT, V4, P51
   Uygur F, 2008, CENT EUR J MED, V3, P417, DOI 10.2478/s11536-008-0042-x
   Valenzuela Andres Roldan, 2008, Rev Enferm, V31, P7
   Vanscheidt W, 2012, INT WOUND J, V9, P316, DOI 10.1111/j.1742-481X.2011.00886.x
   Vermeulen H, 2010, J HOSP INFECT, V76, P191, DOI 10.1016/j.jhin.2010.04.026
   Vermeulen H, 2007, COCHRANE DB SYST REV, V24
   Vogt PM, 2001, WOUND REPAIR REGEN, V9, P116, DOI 10.1046/j.1524-475x.2001.00116.x
   Wang L., 2007, Journal of Burns and Wounds, V6, P65
   Werthén M, 2004, J ANTIMICROB CHEMOTH, V54, P772, DOI 10.1093/jac/dkh407
   White RJ, 2006, OSTOMY WOUND MANAG, V52, P50
   Wiegand C, 2017, J WOUND CARE, V26, P462, DOI 10.12968/jowc.2017.26.8.462
   Wiegand C, 2014, SKIN PHARMACOL PHYS, V27, P25, DOI 10.1159/000351353
   Wiegand C, 2016, SKIN PHARMACOL PHYS, V29, P257, DOI 10.1159/000450889
   Wiegand C, 2015, J MATER SCI-MATER M, V26, DOI 10.1007/s10856-015-5571-7
   Wiegand C, 2015, SKIN PHARMACOL PHYS, V28, P147, DOI 10.1159/000367632
   Wiegand C, 2007, GMS HYG INFECT CONTR, V2
   Wiegand C, 2009, WOUND REPAIR REGEN, V17, P730, DOI 10.1111/j.1524-475X.2009.00536.x
   WILLATTS SM, 1995, CRIT CARE MED, V23, P1033, DOI 10.1097/00003246-199506000-00007
   Willy C, 2017, UNFALLCHIRURG, V120, P549, DOI 10.1007/s00113-017-0375-5
   Wilson J, 2005, ADV SKIN WOUND CARE, V18, P37
   Wohlrab J, 2007, SKIN PHARMACOL PHYS, V20, P71, DOI 10.1159/000097653
   Wolvos TA, 2006, WOUNDS, P11
   Wolvos T, 2015, J WOUND CARE, V24, P15, DOI 10.12968/jowc.2015.24.Sup4b.15
   World Health Organization, 2008, PREV MAN WOUND INF G
   Wound Healing & Management Node, 2013, WOUND PRACT RES, V21, P82
   Zhou LH, 2002, BRIT J DERMATOL, V146, P365, DOI 10.1046/j.1365-2133.2002.04605.x
NR 314
TC 221
Z9 276
U1 1
U2 50
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 1660-5527
EI 1660-5535
J9 SKIN PHARMACOL PHYS
JI Skin Pharmacol. Physiol.
PY 2018
VL 31
IS 1
BP 28
EP 58
DI 10.1159/000481545
PG 31
WC Dermatology; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Pharmacology & Pharmacy
GA FT4GK
UT WOS:000423111400004
PM 29262416
DA 2026-07-24
ER

PT J
AU Guo, Q
AF Guo, Quan
TI Comparison and evaluation of negative pressure wound therapy versus
   standard wound care in the treatment of diabetic foot ulcers
SO BMC SURGERY
LA English
DT Article
DE Comparison; Evaluation; Negative pressure wound therapy; Standard wound
   care; Diabetic foot ulcers
ID MANAGEMENT; CHALLENGES; PERFUSION
AB Background To explore the efficacy, safety, and cost implications of NPWT versus standard wound care (SWC) for Diabetic Foot Ulcers (DFUs). Methods 91 patients with DFUs were included in this retrospective study from May 2017 and February 2024. All patients were divided into NPWT (n = 44) and SWC (n = 47) groups based on the surgery methods. Arterial disease severity was assessed via ankle-brachial index (ABI) and Doppler ultrasound, with subgroups categorized as severe ischemia (ABI < 0.4), moderate ischemia (ABI 0.4-0.7), and normal/mild ischemia (ABI > 0.7). Baseline characteristics, wound parameters, healing progression, adverse events, costs, and subgroup outcomes by arterial disease status were compared between two groups. Results At the 4-week assessment, the NPWT group exhibited significantly higher mean percentage reduction in wound area (35.01% vs. 32.53%, P = 0.033) and greater reduction in wound depth (2.74 mm vs. 2.14 mm, P = 0.032) compared to the SWC group. A notably higher proportion of NPWT patients achieved complete wound closure (52.27% vs. 27.66%, P = 0.029), resolution of infection (88.64% vs. 68.09%, P = 0.035), and neuropathy improvement (59.09% vs. 34.04%, P = 0.029). NPWT also showed lower wound infection rates (9.09% vs. 29.79%, P = 0.027) but higher skin irritation (31.82% vs. 10.64%, P = 0.026). Subgroup analysis revealed NPWT's superiority in both PAD-positive (48.0% vs. 20.0%, RR = 2.40, 95% CI: 1.12-5.15, P = 0.042) and PAD-negative subgroups (55.2% vs. 30.4%, RR = 1.82, 95% CI: 1.05-3.15, P = 0.031). Even in severe ischemia (ABI < 0.4), NPWT achieved higher closure rates (36.4% vs. 12.5%, P = 0.038). While total treatment costs were comparable (P = 0.084), NPWT reduced hospitalization days (16.05 vs. 21.38 days, P = 0.028) and drug costs (5229.33 RMB vs. 5915.5 RMB, P = 0.030). Conclusion NPWT is more superior in safety, cost-efficiency, and long-term wound management compared to SWC. Trial registrationNot applicable.
C1 [Guo, Quan] Univ South China, Cent Hosp Yongzhou, Dept Orthoped, Yongzhou Hosp, 396 Yiyun Rd, Yongzhou 425000, Hunan, Peoples R China.
C3 University of South China
RP Guo, Q (通讯作者)，Univ South China, Cent Hosp Yongzhou, Dept Orthoped, Yongzhou Hosp, 396 Yiyun Rd, Yongzhou 425000, Hunan, Peoples R China.
EM sinewoomph@hotmail.com
RI Guo, Quan/NUP-6934-2025
CR Feldman Eva L, 2019, Nat Rev Dis Primers, V5, P41, DOI [10.1038/s41572-019-0097-9, 10.1038/s41572-019-0097-9, 10.1038/s41572-019-0092-1]
   Bates-Jensen BM., 2019, J Wound Ostomy Cont Nurs, V46, P198
   Bellomo TR, 2022, SEMIN VASC SURG, V35, P219, DOI 10.1053/j.semvascsurg.2022.04.002
   Bota O, 2022, MICROVASC RES, V140, DOI 10.1016/j.mvr.2021.104301
   Campitielio F, 2021, J WOUND CARE, V30, P121, DOI 10.12968/jowc.2021.30.2.121
   Castro-Martins P, 2024, BIOENGINEERING-BASEL, V11, DOI 10.3390/bioengineering11090886
   Ceriello A, 2021, CARDIOVASC DIABETOL, V20, DOI 10.1186/s12933-021-01289-4
   Chen L, 2021, ANN PALLIAT MED, V10, P10830, DOI 10.21037/apm-21-2476
   Everett E, 2018, ANN NY ACAD SCI, V1411, P153, DOI 10.1111/nyas.13569
   Geraghty T, 2019, EXPERT REV PHARM OUT, V19, P279, DOI 10.1080/14737167.2019.1567337
   Horch RE, 2020, EXPERT REV MED DEVIC, V17, P139, DOI 10.1080/17434440.2020.1714434
   International Working Group on the Diabetic Foot (IWGDF), 2023, Diabetes Metab Res Rev, V39, pe3647
   Janssen AHJ, 2022, SURGERY, V172, P349, DOI 10.1016/j.surg.2022.01.037
   Kirsner RS, 2021, WOUND REPAIR REGEN, V29, P908, DOI 10.1111/wrr.12966
   Kolaric V, 2022, ACTA CLIN CROAT, V61, P520, DOI 10.20471/acc.2022.61.03.18
   Liu ZM, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD010318.pub3
   Ma ZJ, 2017, INT J MOL MED, V40, P1415, DOI 10.3892/ijmm.2017.3131
   Marston WA, 2015, ADV WOUND CARE, V4, P75, DOI 10.1089/wound.2014.0575
   Mills JL, 2014, J VASC SURG, V59, P220, DOI 10.1016/j.jvs.2013.08.003
   Monteiro-Soares M, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3273
   Moog P, 2021, J WOUND CARE, V30, P604, DOI 10.12968/jowc.2021.30.8.604
   Oni D, 2020, WOUND MANAG PREV, V66, P16, DOI 10.25270/wmp.2020.4.1625
   Rullan M, 2008, DIABETIC MED, V25, P1090, DOI 10.1111/j.1464-5491.2008.02527.x
   Seidel D, 2022, J FOOT ANKLE RES, V15, DOI 10.1186/s13047-022-00569-w
   Shah A, 2019, ANN PLAS SURG, V82, pS222, DOI 10.1097/SAP.0000000000001842
   Srivastava V, 2022, J FAM MED PRIM CARE, V11, P7001, DOI 10.4103/jfmpc.jfmpc_72_22
   Sun Haojie, 2024, J WOUND CARE, V33
   Teot L, 2021, PLAST RECONSTR SURG, V147, p9S, DOI 10.1097/PRS.0000000000007628
   Webster J, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub4
   Widigdo DAM, 2024, CURR DIABETES REV, V20, DOI 10.2174/0115733998229877230926073555
   Yang K, 2022, BIOMED PHARMACOTHER, V148, DOI 10.1016/j.biopha.2022.112717
   Yang L, 2022, WORLD J DIABETES, V13, P1014, DOI 10.4239/wjd.v13.i12.1014
NR 32
TC 6
Z9 6
U1 3
U2 7
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2482
J9 BMC SURG
JI BMC Surg.
PD MAY 15
PY 2025
VL 25
IS 1
AR 208
DI 10.1186/s12893-025-02885-x
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 2PY2N
UT WOS:001488515400002
PM 40369497
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Zhong, LL
   Wang, F
AF Zhong, Linlin
   Wang, Feng
TI 被撤回的出版物: Comparative analysis of wound healing techniques in
   postoperative bladder cancer patients (Retracted article. See vol. 22,
   2025)
SO INTERNATIONAL WOUND JOURNAL
LA English
DT Article; Retracted Publication
DE advanced wound healing techniques; bioactive dressings; bladder cancer;
   tissue-engineered products; negative pressure wound therapy
ID RADICAL CYSTECTOMY
AB Bladder cancer is a highly prevalent malignancy that presents significant difficulties in the management of wounds following surgery. The present study investigated the critical necessity to optimize wound healing techniques in patients undergoing bladder cancer surgery by contrasting conventional approaches with advanced modalities in order to promote recovery and mitigate complications. The study assessed the efficacy of conventional and advanced wound healing methods in these patients, taking into account the complex interaction of patient-specific factors and surgical complexities. A cross-sectional analysis was performed on 120 patients who underwent bladder cancer surgery at the first affiliated hospital of Wenzhou Medical University. In addition to medical record evaluations and direct wound assessments, patient interviews were utilized to gather information regarding demographics, surgical specifics, wound healing methodologies and postoperative results. Survival analysis and logistic regression were utilized in statistical analysis, with potential confounding variables such as age, comorbidities and type of surgery being accounted for. Advanced wound healing techniques, such as negative pressure wound therapy, tissue-engineered products, bioactive dressings and platelet-rich plasma (PRP), exhibited distinct advantage in comparison with conventional suturing. The aforementioned techniques, especially PRP, resulted in expedited wound healing, decreased rates of complications (p < 0.05) and enhanced secondary outcomes, including curtailed hospital stays and decreased rates of readmissions. PRP therapy, in particular, demonstrated significant improvements with the faster mean time to wound healing of 9 +/- 2 days and lower complication incidence of 2 (6.7%) (p < 0.05), indicating its superior efficacy. A subgroup analysis revealed that younger patients, males and those undergoing laparoscopic surgery exhibited superior outcomes (p < 0.05). The results were further supported by logistic regression and Cox proportional hazards models, which further indicated that sophisticated techniques, notably PRP therapy with a hazard ratio of 3.00 (2.00-4.50) and adjusted odds ratio of 0.20 (0.09-0.43), were effective in improving postoperative recovery. The research clarified the significant advantages that advanced wound healing techniques offered in postoperative care of patients diagnosed with bladder cancer. By customizing these methods to suit the unique requirements of individual patients and specific circumstances of surgical procedures, they can significantly enhance the recuperation process after surgery and set a new standard for patient care.
C1 [Zhong, Linlin] Wenzhou Med Univ, Affiliated Hosp 1, Urol Nursing Dept, Urol Nursing Unit, Wenzhou, Peoples R China.
   [Wang, Feng] Wenzhou Med Univ, Affiliated Hosp 1, Dept Urol, Wenzhou, Peoples R China.
C3 Wenzhou Medical University; Wenzhou Medical University
RP Wang, F (通讯作者)，Wenzhou Med Univ, Affiliated Hosp 1, Dept Urol, Wenzhou, Peoples R China.
EM fengyuan-@163.com
FU Zhejiang Provincial Health Department project
FX No Statement Availabler No Statement Available
CR 30th Annual Meeting of the Wound Healing Society SAWCSpring/WHS Joint Meeting, 2018, Wound Repair Regen, V26, pA1, DOI [10.1111/wrr.12622, DOI 10.1111/WRR.12622]
   Akagi I, 2012, ONCOL LETT, V4, P97, DOI 10.3892/ol.2012.687
   Chang BP, 2019, GEN HOSP PSYCHIAT, V60, P83, DOI 10.1016/j.genhosppsych.2019.07.014
   Chen JA, 2022, EVID-BASED COMPL ALT, V2022, DOI 10.1155/2022/1681038
   Dai SX, 2023, WORLD J SURG ONCOL, V21, DOI 10.1186/s12957-023-03031-8
   Diller RB, 2022, BIOMIMETICS-BASEL, V7, DOI 10.3390/biomimetics7030087
   Ding WW, 2022, BMC NEUROL, V22, DOI 10.1186/s12883-022-02597-2
   Frykberg RG, 2015, ADV WOUND CARE, V4, P560, DOI 10.1089/wound.2015.0635
   Güler Y, 2020, INT WOUND J, V17, P957, DOI 10.1111/iwj.13347
   Guo S, 2010, J DENT RES, V89, P219, DOI 10.1177/0022034509359125
   Gupta P, 2009, INDIAN J UROL, V25, P207, DOI 10.4103/0970-1591.52916
   Herrod PJ, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD013439.pub2
   Heyer K, 2013, DERMATOLOGY, V226, P172, DOI 10.1159/000348331
   Huang HW, 2021, INT J UROL, V28, P673, DOI 10.1111/iju.14537
   Karl A, 2014, J UROLOGY, V191, P335, DOI 10.1016/j.juro.2013.08.019
   Ke XQ, 2022, CONTRAST MEDIA MOL I, V2022, DOI 10.1155/2022/7748696
   Kolimi P, 2022, CELLS-BASEL, V11, DOI 10.3390/cells11152439
   Kramer EA, 2018, ANNU REV BIOMED ENG, V20, P1, DOI 10.1146/annurev-bioeng-071516-044702
   Lee G, 2022, THER ADV UROL, V14, DOI 10.1177/17562872221109022
   Lisinski J, 2022, INT J ENV RES PUB HE, V19, DOI 10.3390/ijerph192315995
   Monika P, 2022, FRONT NUTR, V8, DOI 10.3389/fnut.2021.791899
   Nasrallah AA, 2021, THER ADV UROL, V13, DOI 10.1177/17562872211060570
   Primiano Mike, 2011, AORN J, V94, P555, DOI 10.1016/j.aorn.2011.03.014
   Roche JJW, 2005, BMJ-BRIT MED J, V331, P1374, DOI 10.1136/bmj.38643.663843.55
   Rodrigues M, 2019, PHYSIOL REV, V99, P665, DOI 10.1152/physrev.00067.2017
   Schultz GS., 2011, Mechanisms of Vascular Disease: A Reference Book for Vascular Specialists, DOI DOI 10.1017/UPO9781922064004.024
   Tan WS, 2015, ADV UROL, V2015, DOI 10.1155/2015/323157
   Waraich TA., 2023, Cureus, V15, DOI [10.7759/cureus.50646, DOI 10.7759/CUREUS.50646]
   Xia LM, 2020, J CANCER EDUC, V35, P301, DOI 10.1007/s13187-018-1465-y
NR 29
TC 2
Z9 4
U1 0
U2 9
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1742-4801
EI 1742-481X
J9 INT WOUND J
JI Int. Wound J.
PD MAR
PY 2024
VL 21
IS 3
AR e14820
DI 10.1111/iwj.14820
PG 9
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA KE9G6
UT WOS:001178393000001
PM 38425151
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Seidelman, JL
   Mantyh, CR
   Anderson, DJ
AF Seidelman, Jessica L.
   Mantyh, Christopher R.
   Anderson, Deverick J.
TI Surgical Site Infection Prevention A Review
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Review
ID PROSTHETIC JOINT INFECTION; STAPHYLOCOCCUS-AUREUS; SAFETY CHECKLIST;
   RISK-FACTOR; ANTIMICROBIAL-PROPHYLAXIS; CARDIOTHORACIC SURGERY;
   COLORECTAL SURGERY; WOUND-INFECTION; UNITED-STATES; CONTAMINATION
AB ImportanceApproximately 0.5% to 3% of patients undergoing surgery will experience infection at or adjacent to the surgical incision site. Compared with patients undergoing surgery who do not have a surgical site infection, those with a surgical site infection are hospitalized approximately 7 to 11 days longer.ObservationsMost surgical site infections can be prevented if appropriate strategies are implemented. These infections are typically caused when bacteria from the patient's endogenous flora are inoculated into the surgical site at the time of surgery. Development of an infection depends on various factors such as the health of the patient's immune system, presence of foreign material, degree of bacterial wound contamination, and use of antibiotic prophylaxis. Although numerous strategies are recommended by international organizations to decrease surgical site infection, only 6 general strategies are supported by randomized trials. Interventions that are associated with lower rates of infection include avoiding razors for hair removal (4.4% with razors vs 2.5% with clippers); decolonization with intranasal antistaphylococcal agents and antistaphylococcal skin antiseptics for high-risk procedures (0.8% with decolonization vs 2% without); use of chlorhexidine gluconate and alcohol-based skin preparation (4.0% with chlorhexidine gluconate plus alcohol vs 6.5% with povidone iodine plus alcohol); maintaining normothermia with active warming such as warmed intravenous fluids, skin warming, and warm forced air to keep the body temperature warmer than 36 degrees C (4.7% with active warming vs 13% without); perioperative glycemic control (9.4% with glucose 150 mg/dL); and use of negative pressure wound therapy (9.7% with vs 15% without). Guidelines recommend appropriate dosing, timing, and choice of preoperative parenteral antimicrobial prophylaxis.Conclusions and RelevanceSurgical site infections affect approximately 0.5% to 3% of patients undergoing surgery and are associated with longer hospital stays than patients with no surgical site infections. Avoiding razors for hair removal, maintaining normothermia, use of chlorhexidine gluconate plus alcohol-based skin preparation agents, decolonization with intranasal antistaphylococcal agents and antistaphylococcal skin antiseptics for high-risk procedures, controlling for perioperative glucose concentrations, and using negative pressure wound therapy can reduce the rate of surgical site infections.
C1 [Seidelman, Jessica L.; Anderson, Deverick J.] Duke Univ Sch Med, Duke Ctr Antimicrobial Stewardship & Infect Preven, Durham, NC USA.
   [Mantyh, Christopher R.] Duke Univ Sch Med, Dept Surg, Durham, NC USA.
   [Anderson, Deverick J.] Box 102359, Durham, NC 27710 USA.
C3 Duke University; Duke University
RP Anderson, DJ (通讯作者)，Box 102359, Durham, NC 27710 USA.
EM deverick.anderson@duke.edu
RI mantyh, christopher/AAJ-9140-2021
CR Aghdassi SJS, 2019, ANTIMICROB RESIST IN, V8, DOI 10.1186/s13756-019-0547-x
   Anderson DJ, 2010, INFECT CONT HOSP EP, V31, P701, DOI 10.1086/653205
   Anderson DJ, 2009, PLOS ONE, V4, DOI 10.1371/journal.pone.0008305
   Anderson DJ, 2014, INFECT CONT HOSP EP, V35, P605, DOI 10.1086/676022
   Ban KA, 2017, J AM COLL SURGEONS, V224, P59, DOI 10.1016/j.jamcollsurg.2016.10.029
   BERARD F, 1964, Ann Surg, V160, P1
   Berbari EF, 1998, CLIN INFECT DIS, V27, P1247, DOI 10.1086/514991
   Berbari EF, 2010, CLIN INFECT DIS, V50, P8, DOI 10.1086/648676
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Branch-Elliman W, 2019, JAMA SURG, V154, P590, DOI 10.1001/jamasurg.2019.0569
   Bratzler Dale W., Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery
   Chen S, 2020, WORLD J SURG, V44, P1412, DOI 10.1007/s00268-020-05384-7
   Darouiche RO, 2010, NEW ENGL J MED, V362, P18, DOI 10.1056/NEJMoa0810988
   Dencker EE, 2021, BMC SURG, V21, DOI 10.1186/s12893-021-01392-z
   Dumville JC, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003091.pub4
   Edmiston CE Jr, 2005, SURGERY, V138, P573, DOI 10.1016/j.surg.2005.06.045
   ELEK SD, 1957, BRIT J EXP PATHOL, V38, P573
   Portillo ME, 2012, J INFECTION, V65, P541, DOI 10.1016/j.jinf.2012.08.018
   Fagernes M, 2011, J ADV NURS, V67, P297, DOI 10.1111/j.1365-2648.2010.05462.x
   Faraday N, 2013, ANN SURG, V257, P150, DOI 10.1097/SLA.0b013e3182588abf
   Filsouti F, 2007, J HEART LUNG TRANSPL, V26, P1084, DOI 10.1016/j.healun.2007.07.036
   Gantz O, 2019, AM SURGEON, V85, P142
   Ghosh S, 2006, KNEE, V13, P324, DOI 10.1016/j.knee.2006.05.001
   Grober ED, 2013, J SEX MED, V10, P589, DOI 10.1111/j.1743-6109.2012.02904.x
   Hadiati DR, 2020, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD007462.pub5
   HALEY RW, 1985, AM J EPIDEMIOL, V121, P182, DOI 10.1093/oxfordjournals.aje.a113990
   Harbarth S, 2008, JAMA-J AM MED ASSOC, V299, P1149, DOI 10.1001/jama.299.10.1149
   Harrington G, 2004, INFECT CONT HOSP EP, V25, P472, DOI 10.1086/502424
   Haynes AB, 2009, NEW ENGL J MED, V360, P491, DOI 10.1056/NEJMsa0810119
   Hennessey DB, 2010, ANN SURG, V252, P325, DOI 10.1097/SLA.0b013e3181e9819a
   Hopf HW, 2008, BEST PRACT RES-CLIN, V22, P553, DOI 10.1016/j.bpa.2008.06.001
   Kao LS, 2013, SURG INFECT, V14, P437, DOI 10.1089/sur.2013.008
   Karlsen OE, 2020, J ORTHOP SURG RES, V15, DOI 10.1186/s13018-020-01877-2
   Kaye KS, 2009, J AM GERIATR SOC, V57, P46, DOI 10.1111/j.1532-5415.2008.02053.x
   Kiran RP, 2013, ANN SURG, V258, P599, DOI 10.1097/SLA.0b013e3182a501e3
   Kline SE, 2018, INFECT CONT HOSP EP, V39, P1340, DOI 10.1017/ice.2018.228
   Korol E, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0083743
   Kotagal M, 2015, ANN SURG, V261, P97, DOI 10.1097/SLA.0000000000000688
   Kurz A, 1996, NEW ENGL J MED, V334, P1209, DOI 10.1056/NEJM199605093341901
   Latham R, 2001, INFECT CONT HOSP EP, V22, P607, DOI 10.1086/501830
   Leaper DJ, 2017, J HOSP INFECT, V95, P135, DOI 10.1016/j.jhin.2016.12.016
   Lee KY, 2011, J KOREAN SURG SOC, V81, P295, DOI 10.4174/jkss.2011.81.5.295
   LIDWELL OM, 1983, J HOSP INFECT, V4, P111, DOI 10.1016/0195-6701(83)90041-5
   Loftus RW, 2011, ANESTH ANALG, V112, P98, DOI 10.1213/ANE.0b013e3181e7ce18
   Madrid E, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009016.pub2
   Magill SS, 2014, NEW ENGL J MED, V370, P1198, DOI 10.1056/NEJMoa1306801
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Manian FA, 2014, CLIN INFECT DIS, V59, P1272, DOI 10.1093/cid/ciu552
   McDonald M, 1998, AUST NZ J SURG, V68, P388, DOI 10.1111/j.1445-2197.1998.tb04785.x
   McLaws M L, 2000, J Qual Clin Pract, V20, P6, DOI 10.1046/j.1440-1762.2000.00347.x
   Meijs AP, 2019, INFECT CONT HOSP EP, V40, P991, DOI 10.1017/ice.2019.165
   Ming DY, 2012, INFECT CONT HOSP EP, V33, P276, DOI 10.1086/664053
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   O'Hara LM, 2018, AM J INFECT CONTROL, V46, P602, DOI 10.1016/j.ajic.2018.01.018
   Payne Wyatt G, 2008, Eplasty, V8, pe9
   Perl TM, 2002, NEW ENGL J MED, V346, P1871, DOI 10.1056/NEJMoa003069
   Rennert-May E, 2019, ANTIMICROB RESIST IN, V8, DOI 10.1186/s13756-019-0568-5
   Rohde JM, 2014, JAMA-J AM MED ASSOC, V311, P1317, DOI 10.1001/jama.2014.2726
   Roig-Rosello E, 2020, BIOMOLECULES, V10, DOI 10.3390/biom10121607
   Schweizer M, 2013, BMJ-BRIT MED J, V346, DOI 10.1136/bmj.f2743
   Scott R.D., 2009, Centers for Disease Control and Prevention, Division of Healthcare Quality Promotion, National Center for Preparedness, Detection
   Seidelman JL, 2023, INFECT CONT HOSP EP, V44, P1255, DOI 10.1017/ice.2022.236
   Seidelman JL, 2023, INFECT CONT HOSP EP, V44, P610, DOI 10.1017/ice.2022.135
   Stambough JB, 2017, J ARTHROPLASTY, V32, P728, DOI 10.1016/j.arth.2016.09.041
   Steinberg JP, 2009, ANN SURG, V250, P10, DOI 10.1097/SLA.0b013e3181ad5fca
   Surgical site infection event (SSI), SURG SIT INF EV SSI
   Tammelin A, 2001, J HOSP INFECT, V47, P266, DOI 10.1053/jhin.2000.0914
   Tande AJ, 2016, AM J MED, V129, DOI 10.1016/j.amjmed.2015.09.006
   Tanner J, 2021, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004122.pub5
   van Klei WA, 2012, ANN SURG, V255, P44, DOI 10.1097/SLA.0b013e31823779ae
   Wang YY, 2018, BMC ENDOCR DISORD, V18, DOI 10.1186/s12902-018-0268-9
   Wang Z, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0091755
   Weiser TG, 2010, ANN SURG, V251, P976, DOI 10.1097/SLA.0b013e3181d970e3
   Wenzel RP, 2019, INFECT CONT HOSP EP, V40, P590, DOI 10.1017/ice.2018.363
   Wetterslev J, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008884.pub2
   Wilson BM, 2019, JAMA NETW OPEN, V2, DOI 10.1001/jamanetworkopen.2019.16003
   Wukich DK, 2011, DIABETES CARE, V34, P2211, DOI 10.2337/dc11-0846
   Yuan K, 2013, INT J SURG, V11, P383, DOI 10.1016/j.ijsu.2013.02.018
   Zajonz D, 2015, PATIENT SAF SURG, V9, DOI 10.1186/s13037-015-0071-8
   Zhang Y, 2015, AM J INFECT CONTROL, V43, P810, DOI 10.1016/j.ajic.2015.04.003
   Zhu CC, 2020, RADIOLOGY, V294, P707, DOI 10.1148/radiol.2020191723
   Zimlichman E, 2013, JAMA INTERN MED, V173, P2039, DOI 10.1001/jamainternmed.2013.9763
   Zwanenburg PR, 2020, ANN SURG, V272, P81, DOI 10.1097/SLA.0000000000003644
NR 83
TC 394
Z9 488
U1 26
U2 162
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD JAN 17
PY 2023
VL 329
IS 3
BP 244
EP 252
DI 10.1001/jama.2022.24075
PG 9
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA G3PQ9
UT WOS:000988321100016
PM 36648463
HC Y
HP N
DA 2026-07-24
ER

PT J
AU Haque, S
   Kanapathy, M
   Bollen, E
   Mosahebi, A
   Younis, I
AF Haque, Shameem
   Kanapathy, Muholan
   Bollen, Edward
   Mosahebi, Afshin
   Younis, Ibby
TI Patient-reported outcome and cost implication of acute salvage of
   infected implant-based breast reconstruction with negative pressure
   wound therapy with Instillation (NPWTi) compared to standard care
SO JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
LA English
DT Article
DE Cost; Patient reported outcome; Breast implant; Infection; NPWTi
ID COMPLICATIONS; SATISFACTION; SURGERY; FLAP
AB Introduction: Implant loss due to infection is the most devastating complication of implant-based breast reconstruction. The use of negative pressure wound therapy with instillation(NPWTi) for salvage of infected implant-based breast reconstructions has shown promising results allowing early reinsertion of a new implant as an alternative to the current management with delayed reinsertion. This study compares the patient-reported outcome and cost implication of NPWTi to the current management.
   Methods: Twenty cases of infected breast implants treated with NPWTi(V.A.C. VERAFLO (TM) Therapy), followed by early reinsertion of new implants were compared to 20 cases that had delayed reinsertion(non-NPWTi). Patient satisfaction was evaluated using the BREAST-Q questionnaire. The average cost per patient was calculated using total operative expense, cost of inpatient stay, investigations, antibiotics, and outpatient visits.
   Results: Treatment with NPWTi allowed earlier reinsertion of a new implant (NPWTi: 10.3 +/- 2.77days vs. non-NPWTi: 247.45 +/- 111.28days, p < 0.001). Patients in the NPWTi group reported higher satisfaction. The average cost per patient for NPWTi and non-NPWTi was 14,343.13 pound +/-2,786.70 pound and 8,920.31 pound +/-3,005.73 pound, respectively(p<0.001). All patients treated with NPWTi had one admission and spent 11.9 +/- 4.1days as inpatients, while non-NPWTi patients had 2.1 +/- 0.3 admissions(p<0.001) and spent 7.1 +/- 5.8days(p<0.004) as inpatients. Patients treated with NPWTi had more procedures (NPWTi:3.35 +/- 0.81 Vs. non-NPWTi:2.2 +/- 0.41, p = 0.006); however, three non-NPWTi cases required flap reconstruction.
   Conclusion: Patients treated with NPWTi reported higher satisfaction, received a new and earlier implant, and had fewer admissions and outpatient visits; however, they incurred higher average costs, longer inpatient stays, and underwent more procedures. Early implant reinsertion preserves skin envelope; hence avoiding additional cost and stress related to further major autologous reconstruction. (C) 2021 Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons.
C1 [Haque, Shameem; Kanapathy, Muholan; Mosahebi, Afshin; Younis, Ibby] Royal Free NHS Fdn Trust Hosp, Dept Plast & Reconstruct Surg, London NW3 2QG, England.
   [Kanapathy, Muholan; Mosahebi, Afshin] UCL, Div Surg & Intervent Sci, London, England.
   [Bollen, Edward] UCL, UCL Med Sch, London, England.
C3 University of London; University College London; University of London;
   University College London
RP Kanapathy, M (通讯作者)，Royal Free NHS Fdn Trust Hosp, Dept Plast & Reconstruct Surg, London NW3 2QG, England.; Kanapathy, M (通讯作者)，UCL, Div Surg & Intervent Sci, London, England.
EM m.kanapathy@ucl.ac.uk
RI Kanapathy, Muholan/B-2225-2016
CR Atherton DD, 2011, J PLAST RECONSTR AES, V64, P710, DOI 10.1016/j.bjps.2010.11.001
   Bramhall RJ, 2018, J PLAST RECONSTR AES, V71, P194, DOI 10.1016/j.bjps.2017.10.009
   Brinkert D, 2013, INT WOUND J, V10, P56, DOI 10.1111/iwj.12176
   Cheong JY, 2016, AESTHET PLAST SURG, V40, P745, DOI 10.1007/s00266-016-0668-z
   Davis GB, 2014, ANN PLAS SURG, V72, pS61, DOI 10.1097/SAP.0000000000000171
   de Blacam C, 2012, ANN PLAS SURG, V69, P516, DOI 10.1097/SAP.0b013e318217fb21
   El-Sabawi B, 2017, J PLAST RECONSTR AES, V70, P768, DOI 10.1016/j.bjps.2017.02.015
   Gopie JP, 2013, PSYCHO-ONCOLOGY, V22, P290, DOI 10.1002/pon.2089
   Goyal A, 2011, BRIT J SURG, V98, P1267, DOI 10.1002/bjs.7531
   Halvorson EG, 2007, ANN PLAS SURG, V59, P131, DOI 10.1097/01.sap.0000252716.73356.68
   Jeevan R, 2014, J PLAST RECONSTR AES, V67, P1333, DOI 10.1016/j.bjps.2014.04.022
   Krueger EA, 2001, INT J RADIAT ONCOL, V49, P713, DOI 10.1016/S0360-3016(00)01402-4
   Meybodi F, 2017, ANZ J SURG, V87, pE293, DOI 10.1111/ans.13379
   Mylvaganam S, 2017, BREAST, V35, P182, DOI 10.1016/j.breast.2017.07.016
   Pirro O, 2017, PRS-GLOB OPEN, V5, DOI 10.1097/GOX.0000000000001217
   Poppler LH, 2019, PLAST RECONSTR SURG, V143, P24, DOI 10.1097/PRS.0000000000005131
   Potter S, 2019, LANCET ONCOL, V20, P254, DOI 10.1016/S1470-2045(18)30781-2
   Pusic AL, 2009, PLAST RECONSTR SURG, V124, P345, DOI 10.1097/PRS.0b013e3181aee807
   Serrurier LCJ, 2017, PLAST RECONSTR SURG, V139, P809, DOI 10.1097/PRS.0000000000003222
   Sinha I, 2017, PLAST RECONSTR SURG, V139, P20, DOI 10.1097/PRS.0000000000002839
   Yan C, 2015, J PLAST SURG HAND SU, V49, P166, DOI 10.3109/2000656X.2014.970639
   Yueh JH, 2010, PLAST RECONSTR SURG, V125, P1585, DOI 10.1097/PRS.0b013e3181cb6351
NR 22
TC 13
Z9 16
U1 0
U2 1
PU ELSEVIER SCI LTD
PI London
PA 125 London Wall, London, ENGLAND
SN 1748-6815
EI 1878-0539
J9 J PLAST RECONSTR AES
JI J. Plast. Reconstr. Aesthet. Surg.
PD DEC
PY 2021
VL 74
IS 12
BP 3300
EP 3306
DI 10.1016/j.bjps.2021.05.014
EA NOV 2021
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA XG9IZ
UT WOS:000725060900007
PM 34217644
DA 2026-07-24
ER

PT J
AU Salmenkylä, T
   Kilpivaara, K
   Ohtonen, P
   Rautio, T
   Mäkäräinen, E
AF Salmenkyla, Tellu
   Kilpivaara, Katariina
   Ohtonen, Pasi
   Rautio, Tero
   Makarainen, Elisa
TI Case control study investigating the clinical utility of NPWT in the
   perineal region following abdominoperineal resection for rectal
   adenocarcinoma: a single center study
SO BMC SURGERY
LA English
DT Article
DE Abdominoperineal resection; Incisional negative-pressure wound therapy;
   Perineal reconstruction; Rectal adenocarcinoma
ID CANCER; THERAPY; CLOSURE
AB Background Perineal wound complications are common after abdominoperineal resection (APR) for rectal adenocarcinoma. Delayed wound healing may postpone postoperative adjuvant therapy and, therefore, lead to a worse survival rate. Negative-pressure wound therapy (NPWT) has been suggested to improve healing, but research on this subject is limited. Methods The aim of this study was to assess whether NPWT reduces surgical site infections (SSI) after APR for rectal adenocarcinoma when the closure is performed with a biological mesh and a local flap. A total of 21 consecutive patients had an NPWT device (Avelle, Convatec (TM)) applied to the perineal wound. The study patients were compared to a historical cohort in a case-control setting in relation to age, body mass index, tumor stage, and length of neoadjuvant radiotherapy. The primary outcome was the surgical site infection rate. The secondary outcomes were the wound complication rate, the severity of wound complications measured by the Clavien-Dindo classification, length of hospital stay, and surgical revision rate. Results The SSI rate was 33% (7/21) in the NPWT group and 48% (10/21) in the control group, p = 0.55. The overall wound complication rate was 62% (13/21) in NPWT patients and 67% (14/21) in the control group, p > 0.90. The length of hospital stay was 15 days in the NPWT group and 13 in the control group, p = 0.34. The wound severity according to the Clavien-Dindo classification was 3b in 29% (6/21) of the NPWT group and in 38% (8/21) of the control group. A surgical revision had to be performed in 29% (6/21) of the cases in the NPWT group and 38% (8/21) in the control group, p = 0.73. Conclusion NPWT did not statistically decrease surgical site infections or reduce wound complication severity in perineal wounds after APR in this case-control study. The results may be explained by technical difficulties in applying NPWT in the perineum, especially in female patients. NPWT devices should be further developed to suit the perineal anatomy before their full effect can be assessed. Trial registration The study was registered as a prospective registry study (266/2018, registered 15th of November 2018)
C1 [Salmenkyla, Tellu; Kilpivaara, Katariina; Rautio, Tero; Makarainen, Elisa] Oulu Univ Hosp, Med Res Ctr, Dept Surg, Oulu, Finland.
   [Ohtonen, Pasi] Oulu Univ Hosp, Res Serv Unit, Oulu, Finland.
   [Ohtonen, Pasi] Univ Oulu, Res Unit Surg Anesthesia & Intens Care, Oulu, Finland.
C3 University of Oulu; University of Oulu; University of Oulu
RP Salmenkylä, T (通讯作者)，Oulu Univ Hosp, Med Res Ctr, Dept Surg, Oulu, Finland.
EM tellu.salmenkyla@gmail.com
CR Biagi JJ, 2011, JAMA-J AM MED ASSOC, V305, P2335, DOI 10.1001/jama.2011.749
   Bullard KM, 2005, DIS COLON RECTUM, V48, P438, DOI 10.1007/s10350-004-0827-1
   El-Gazzaz G, 2009, DIS COLON RECTUM, V52, P1962, DOI 10.1007/DCR.0b013e3181b71ef9
   Holm T, 2007, BRIT J SURG, V94, P232, DOI 10.1002/bjs.5489
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Leaper DJ, 2017, J HOSP INFECT, V95, P135, DOI 10.1016/j.jhin.2016.12.016
   Musters GD, 2014, DIS COLON RECTUM, V57, P1129, DOI 10.1097/DCR.0000000000000182
   Norman G, 2020, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009261.pub6, 10.1002/14651858.CD009261.pub5]
   Sahebally SM, 2018, JAMA SURG, V153, DOI 10.1001/jamasurg.2018.3467
   Wells CI, 2019, WORLD J SURG, V43, P2779, DOI 10.1007/s00268-019-05116-6
   Wiatrek Rebecca L, 2008, Clin Colon Rectal Surg, V21, P76, DOI 10.1055/s-2008-1055325
   Zaidi A, 2017, COLORECTAL DIS, V19, P283, DOI 10.1111/codi.13458
NR 12
TC 3
Z9 3
U1 0
U2 2
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2482
J9 BMC SURG
JI BMC Surg.
PD JUL 30
PY 2022
VL 22
IS 1
AR 296
DI 10.1186/s12893-022-01746-1
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 3J6HI
UT WOS:000833494000001
PM 35907824
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ayuso, SA
   Elhage, SA
   Aladegbami, BG
   Kao, AM
   Kercher, KW
   Colavita, PD
   Augenstein, VA
   Heniford, BT
AF Ayuso, Sullivan A.
   Elhage, Sharbel A.
   Aladegbami, Bola G.
   Kao, Angela M.
   Kercher, Kent W.
   Colavita, Paul D.
   Augenstein, Vedra A.
   Heniford, B. Todd
TI Delayed primary closure (DPC) of the skin and subcutaneous tissues
   following complex, contaminated abdominal wall reconstruction (AWR): a
   propensity-matched study
SO SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
LA English
DT Article
DE Delayed primary closure; Contaminated; Hernia; Abdominal wall
   reconstruction; Complication; Surgical site occurrence; Infection;
   Negative pressure wound therapy
ID VENTRAL HERNIA REPAIR; SURGICAL SITE INFECTION; PRESSURE WOUND THERAPY;
   CAROLINAS EQUATION; RECURRENCE; OUTCOMES; DEFECTS; SCORE; COST; CARE
AB Background Wound complications following abdominal wall reconstruction (AWR) in a contaminated setting are common and significantly increase the risk of hernia recurrence. The purpose of this study was to examine the effect of short-term negative pressure wound therapy (NPWT) followed by operative delayed primary closure (DPC) of the skin and subcutaneous tissue after AWR in a contaminated setting. Methods A prospective institutional hernia database was queried for patients who underwent NPWT-assisted DPC after contaminated AWR between 2008 and 2020. Primary outcomes included wound complication rate and reopening of the incision. A non-DPC group was created using propensity-matching. Standard descriptive statistics were used, and a univariate analysis was performed between the DPC and non-DPC groups. Results In total, 110 patients underwent DPC following AWR. The hernias were on average large (188 +/- 133.6 cm(2)), often recurrent (81.5%), and 60.5% required a components separation. All patients had CDC Class 3 (14.5%) or 4 (85.5%) wounds and biologic mesh placed. Using CeDAR, the wound complication rate was estimated to be 66.3%. Postoperatively, 26.4% patients developed a wound complication, but only 5.5% patients required reopening of the wound. The rate of recurrence was 5.5% with mean follow-up of 22.6 +/- 27.1 months. After propensity-matching, there were 73 patients each in the DPC and non-DPC groups. DPC patients had fewer overall wound complications (23.0% vs 43.9%, p = 0.02). While 4.1% of the DPC group required reopening of the incision, 20.5% of patients in the non-DPC required reopening of the incision (p = 0.005) with an average time to healing of 150 days. Hernia recurrence remained low overall (2.7% vs 5.4%, p = 0.17). Conclusions DPC can be performed with a high rate of success in complex, contaminated AWR patients by reducing the rate of wound complications and avoiding prolonged healing times. In patients undergoing AWR in a contaminated setting, a NPWT-assisted DPC should be considered.
C1 [Ayuso, Sullivan A.; Elhage, Sharbel A.; Aladegbami, Bola G.; Kao, Angela M.; Kercher, Kent W.; Colavita, Paul D.; Augenstein, Vedra A.; Heniford, B. Todd] Carolinas Med Ctr, Dept Surg, Gastrointestinal & Minimally Invas Surg, 1025 Morehead Med Dr Suite 300, Charlotte, NC 28204 USA.
C3 Carolinas Medical Center
RP Heniford, BT (通讯作者)，Carolinas Med Ctr, Dept Surg, Gastrointestinal & Minimally Invas Surg, 1025 Morehead Med Dr Suite 300, Charlotte, NC 28204 USA.
EM todd.heniford@gmail.com
CR Augenstein VA, 2015, J AM COLL SURGEONS, V221, pS65, DOI 10.1016/j.jamcollsurg.2015.07.145
   BERNARD HR, 1963, JAMA-J AM MED ASSOC, V184, P290, DOI 10.1001/jama.1963.73700170015010e
   Bhangu A, 2013, JAMA SURG, V148, P779, DOI 10.1001/jamasurg.2013.2336
   Bueno-Lledó J, 2021, ANN SURG, V273, P1081, DOI 10.1097/SLA.0000000000004310
   CDC Oid Ncezid DHQP, 2020, 9 SURG SITE INFECT S
   Cohn SM, 2001, ANN SURG, V233, P409, DOI 10.1097/00000658-200103000-00016
   Cox TC, 2016, J SURG RES, V206, P214, DOI 10.1016/j.jss.2016.08.009
   de Vries FEE, 2017, HERNIA, V21, P583, DOI 10.1007/s10029-017-1620-0
   Deerenberg EB, 2021, SKELETAL RADIOL, V50, P1, DOI 10.1007/s00256-020-03533-6
   Duttaroy DD, 2009, SURG INFECT, V10, P129, DOI 10.1089/sur.2007.030
   EBSCOhost, 2020, 84480119 NEGATIVE PR
   Elhage SA, 2020, PLAST AESTHET RES, V2020, DOI [10.20517/2347-9264.2020.03, DOI 10.20517/2347-9264.2020.03, 10.20517/2347-9264.2020.03]
   Farber BA, 2019, J AM COLL SURGEONS, V229, pS112
   Giordano S, 2017, SURGERY, V161, P499, DOI 10.1016/j.surg.2016.08.009
   Gombert A, 2020, VASCULAR, V28, P274, DOI 10.1177/1708538119890960
   Heniford BT, 2020, ANN SURG, V271, P364, DOI 10.1097/SLA.0000000000002966
   Hepburn HH, 1919, BMJ-BRIT MED J, V1919, P181, DOI 10.1136/bmj.1.3033.181
   Holihan JL, 2015, J AM COLL SURGEONS, V221, P478, DOI 10.1016/j.jamcollsurg.2015.04.026
   Janssen AHJ, 2016, J WOUND CARE, V25, P154, DOI 10.12968/jowc.2016.25.3.154
   Jolissaint JS, 2020, SURGERY, V167, P765, DOI 10.1016/j.surg.2020.01.001
   Kao A., 2018, USE VAC ASSISTED DEL
   Khansa I, 2019, PRS-GLOB OPEN, V7, DOI 10.1097/GOX.0000000000002549
   Krpata DM, 2013, AM J SURG, V205, P354, DOI 10.1016/j.amjsurg.2012.10.013
   Liang MK, 2015, SURG INFECT, V16, P36, DOI 10.1089/sur.2014.115
   Maloney SR, 2019, AM J SURG, V218, P1096, DOI 10.1016/j.amjsurg.2019.10.019
   Maloney SR, 2019, SURGERY, V166, P435, DOI 10.1016/j.surg.2019.05.043
   Ortega G, 2012, J SURG RES, V174, P33, DOI 10.1016/j.jss.2011.05.056
   Otero J, 2018, J AM COLL SURGEONS, V227, pS98, DOI 10.1016/j.jamcollsurg.2018.07.199
   Pauli EM, 2013, SURG INFECT, V14, P270, DOI 10.1089/sur.2012.059
   Pinell-White XA, 2014, ANN PLAS SURG, V72, pS150, DOI 10.1097/SAP.0000000000000100
   Poulose BK, 2012, HERNIA, V16, P179, DOI 10.1007/s10029-011-0879-9
   Rios-Diaz AJ, 2020, J SURG RES, V255, P267, DOI 10.1016/j.jss.2020.03.070
   Rosen MJ, 2017, ANN SURG, V265, P205, DOI 10.1097/SLA.0000000000001601
   Rosen MJ, 2013, ANN SURG, V257, P991, DOI 10.1097/SLA.0b013e3182849871
   Siribumrungwong B, 2018, ANN SURG, V267, P631, DOI 10.1097/SLA.0000000000002464
   Slater NJ, 2015, ANN SURG, V261, P553, DOI 10.1097/SLA.0000000000000733
   Soares KC, 2015, AM J SURG, V209, P324, DOI 10.1016/j.amjsurg.2014.06.022
   Subramonia S, 2009, WORLD J SURG, V33, P931, DOI 10.1007/s00268-009-9947-z
   Wormer BA, 2016, J SURG RES, V202, P461, DOI 10.1016/j.jss.2016.01.029
NR 39
TC 16
Z9 17
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0930-2794
EI 1432-2218
J9 SURG ENDOSC
JI Surg. Endosc.
PD MAR
PY 2022
VL 36
IS 3
BP 2169
EP 2177
DI 10.1007/s00464-021-08485-z
EA MAY 2021
PG 9
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA ZA4UA
UT WOS:000652466800001
PM 34018046
DA 2026-07-24
ER

PT J
AU Schwartz, JA
   Fuller, A
   Avdagic, E
   Gendics, C
   Lantis, JC
AF Schwartz, J. A.
   Fuller, A.
   Avdagic, E.
   Gendics, C.
   Lantis, J. C.
TI Use of NPWT with and without Soft Port technology in infected foot
   wounds undergoing partial diabetic foot amputation
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE negative pressure wound therapy; chronic wounds; pressure ulcers;
   diabetic foot ulcers; amputation
ID THERAPY; TRIAL
AB Objective: Negative pressure wound therapy (NPWT) has previously been shown to be effective in closing diabetic foot wounds that have undergone amputation over a 16-week period. For patients with plantar foot wounds, NPWT is a key therapy. An alternative NPWT with and without a novel soft, flexible port system needs to be evaluated for its comparable efficacy. Our objective was to show the non-inferiority of an alternative negative pressure system, and in a small subset, a novel foam dressing system.
   Method: We performed a single centre prospective study of patients with diabetes undergoing open bone resection in the foot for acutely infected wounds. Wounds were treated with NPWT/Soft Port technology (SPT), for 112 days or until primary closure or the wound was deemed ready for delayed primary closure. Rate of closure and quality of life were analysed. A previously published cohort was used as a control.
   Results: Of the 30 patients initially recruited, 29 met eligibility requirements and had NPWT applied a median of 2 days postoperatively. There were seven patients (24%) who had delayed primary closure (mean=58 days) and 52% had sufficient progress to change in treatment (15/29; mean=62 days). Only one patient reached the 112-day mark without sufficient progress to be closed. The primary method of delayed primary closure was split-thickness skin graft. There was a reduction in wound area 56.3% (initial mean area=17.4cm(2) to final mean area=7.6 cm(2); p=0.001) at the end of treatment (mean=58.7 days) reduced to 4.3cm(2) a 67.2% reduction (p=0.004) at the end of study (112 days).
   Conclusion: The alternative NPWT and the SPT was well tolerated and effective in the population in aggregate. There was no inferiority between the two technologies. The aggregate closure or progression to be ready for closure rate of 75% at 69 days compares very favourably with previously published data for NPWT in this population of 56% at 56 days (range: 26-92 days). Both cohorts did significantly better than previously published standard of care closure rates of 39% at 77 days.
C1 [Schwartz, J. A.; Fuller, A.; Avdagic, E.] St Lukes Roosevelt Hosp, New York, NY 10025 USA.
   [Lantis, J. C.] St Lukes Roosevelt Hosp, Dept Surg, New York, NY USA.
   [Lantis, J. C.] St Lukes Roosevelt Hosp, Vasc Endovasc Surg, New York, NY USA.
   [Fuller, A.; Avdagic, E.; Gendics, C.] Mt Sinai, New York, NY 10025 USA.
C3 Mount Sinai West; Mount Sinai Morningside; Mount Sinai Morningside;
   Mount Sinai West; Mount Sinai West; Mount Sinai Morningside
RP Schwartz, JA (通讯作者)，St Lukes Roosevelt Hosp, New York, NY 10025 USA.
EM jlantis@chpnet.org
FU Smith Nephew; Acelity; Macrocure; Manukamed
FX J.C. Lantis is a paid consultant for Smith & Nephew, Acelity, Macrocure
   and Manukamed. This trial as supported by an institutional grant to St
   Luke's and Roosevelt Hospital sponsored by Smith & Nephew. The outcome
   of the trial had no bearing on the condition of the grant. No
   investigator holds an equity position in Smith & Nephew. C. Gendics is a
   paid consultant of Acelity.
CR Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Joseph E, 2000, WOUNDS, V12, P60
   McCallon S.K., 2000, OSTOMY WOUND MANAG, V46, P8
   Rahmanian-Schwarz A, 2012, BURNS, V38, P573, DOI 10.1016/j.burns.2011.10.010
NR 4
TC 6
Z9 7
U1 0
U2 10
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
J9 J WOUND CARE
JI J. Wound Care
PD SEP
PY 2015
VL 24
IS 9
SU S
BP S4
EP S12
DI 10.12968/jowc.2015.24.Sup9.S4
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA CQ5NK
UT WOS:000360651600002
PM 26352284
DA 2026-07-24
ER

PT J
AU Mihalache, O
   Simion, L
   Doran, H
   Bîrligea, AB
   Luca, DC
   Chitoran, E
   Bobirca, F
   Mustatea, P
   Patrascu, T
AF Mihalache, Octavian
   Simion, Laurentiu
   Doran, Horia
   Birligea, Andra Bontea
   Luca, Dan Cristian
   Chitoran, Elena
   Bobirca, Florin
   Mustatea, Petronel
   Patrascu, Traian
TI Negative Pressure Wound Therapy in the Treatment of Complicated Wounds
   of the Foot and Lower Limb in Diabetic Patients: A Retrospective Case
   Series
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE amputation; diabetic foot; gangrene; negative pressure; NPWT
ID ULCERS; MULTICENTER
AB Background: Diabetes-related foot diseases represent a global health problem because of the associated complications, the risk of amputation, and the economic burden on health systems. Negative pressure wound therapy (NPWT) is a technique that uses sub-atmospheric pressure to help promote wound healing by reducing the inflammatory exudate while keeping the wound moist, inhibiting bacterial growth, and promoting the formation of granulation tissue. Objective: This study aimed to assess the effectiveness of NPWT in preventing major amputation in diabetic patients with complicated foot or lower limb infections and to contextualize the results through a review of the existing literature. Materials and methods: We conducted a retrospective study at the First Surgical Department of "Dr. I. Cantacuzino" Clinical Hospital in Bucharest, Romania, over a 15-year period, including 30 consecutive adult patients with diabetes and soft tissue foot or lower limb infections treated with NPWT. Patients with non-diabetic ulcers, incomplete medical data, or aged under 18 were excluded. All patients underwent initial surgical debridement, minor amputation, or drainage procedures, followed by the application of NPWT using a standard protocol. Dressings were changed every 2-4 days for a total of 7-10 days. Antibiotic therapy was adapted according to the culture results. The primary outcome was limb preservation, defined as avoidance of major amputation. Secondary outcomes included in-hospital mortality and wound status at discharge. Results: NPWT was associated with a favorable outcome in 24 patients (80%), defined by wound granulation or healing without the need for major amputation. Five patients (16.6%) underwent major amputation because of failure of the primary lesion treatment, and one patient died. No statistically significant association was observed between the outcomes and standard classification scores (WIFI, IWGDF, and TPI). A comprehensive literature review helped to integrate these findings into the existing pool of knowledge. Conclusions: NPWT may support limb preservation in selected diabetic foot cases. While the retrospective design and the small sample size of the study limit generalizability, these results reinforce the need for further controlled studies to evaluate NPWT in real-life clinical settings. The correct use of NPWT combined with etiological treatment may offer a maximum chance to avoid major amputation in patients with diabetes-related foot diseases.
C1 [Mihalache, Octavian; Simion, Laurentiu; Doran, Horia; Birligea, Andra Bontea; Luca, Dan Cristian; Chitoran, Elena; Bobirca, Florin; Mustatea, Petronel; Patrascu, Traian] Carol Davila Univ Med & Pharm, Med Sch, Bucharest 050474, Romania.
   [Mihalache, Octavian; Doran, Horia; Bobirca, Florin; Mustatea, Petronel; Patrascu, Traian] Dr I Cantacuzino Clin Hosp, Surg Dept 1, Bucharest 030167, Romania.
   [Simion, Laurentiu; Luca, Dan Cristian; Chitoran, Elena] Bucharest Inst Oncol Prof Dr Alexandru Trestiorean, Gen Surg & Surg Oncol Dept 1, Bucharest 022328, Romania.
C3 Carol Davila University of Medicine & Pharmacy
RP Simion, L; Doran, H (通讯作者)，Carol Davila Univ Med & Pharm, Med Sch, Bucharest 050474, Romania.; Doran, H (通讯作者)，Dr I Cantacuzino Clin Hosp, Surg Dept 1, Bucharest 030167, Romania.; Simion, L (通讯作者)，Bucharest Inst Oncol Prof Dr Alexandru Trestiorean, Gen Surg & Surg Oncol Dept 1, Bucharest 022328, Romania.
EM laurentiu.simion@umfcd.ro; horia.doran@umfcd.ro
RI DORAN, HORIA/N-9456-2013; Luca, Dan/GNP-2621-2022; Florin,
   Bobirca/GYR-2443-2022; Mihalache, Octavian/AAE-9707-2021; Simion,
   Laurențiu/R-3159-2019; Chitoran, Elena/GNP-4533-2022
OI Florin, Bobirca/0000-0002-8944-3857; Mihalache,
   Octavian/0009-0007-1887-0388; Simion, Laurențiu/0000-0002-2996-8125;
   Chitoran, Elena/0000-0001-9225-8030
FU University of Medicine and Pharmacy "Carol Davila"
FX Publication of this paper was supported by the University of Medicine
   and Pharmacy "Carol Davila", through the institutional program "Publish
   not Perish".
CR Apelqvist Jan, 2017, J Wound Care, V26, pS1, DOI [10.12968/jowc.2017.26.sup3.s1, 10.12968/jowc.2017.26.Sup3.S1]
   Armstrong DG, 2017, NEW ENGL J MED, V376, P2367, DOI 10.1056/NEJMra1615439
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Bellomo TR, 2022, SEMIN VASC SURG, V35, P219, DOI 10.1053/j.semvascsurg.2022.04.002
   Biz C, 2022, FOOT ANKLE CLIN, V27, P545, DOI 10.1016/j.fcl.2022.02.003
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Bobirca F, 2016, CHIRURGIA-BUCHAREST, V111, P151
   Borys S, 2019, EUR J CLIN INVEST, V49, DOI 10.1111/eci.13067
   Boulton A, 2022, ADA Clinical Compendia, V2022, P1, DOI [10.2337/db2022-02, DOI 10.2337/DB2022-02, 10.2337/db2022-02]
   Chen L, 2021, ANN PALLIAT MED, V10, P10830, DOI 10.21037/apm-21-2476
   Chen P, 2024, DIABETES-METAB RES, V40, DOI 10.1002/dmrr.3644
   diabetesatlas, IDF-Diabetes Atlas Global Diabetes Data & Statistics
   Eginton MT, 2003, ANN VASC SURG, V17, P645, DOI 10.1007/s10016-003-0065-3
   Elsayed NA, 2024, DIABETES CARE, V47, pS231, DOI 10.2337/dc24-S012
   Guo Q, 2025, BMC SURG, V25, DOI 10.1186/s12893-025-02885-x
   Ji SZ, 2021, BURNS TRAUMA, V9, DOI 10.1093/burnst/tkab018
   Liu ZM, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD010318.pub3
   Löndahl M, 2010, DIABETES CARE, V33, P998, DOI 10.2337/dc09-1754
   Payne JL, 2009, J BIOMED MATER RES B, V89B, P217, DOI 10.1002/jbm.b.31209
   Schaper NC, 2024, DIABETES-METAB RES, V40, DOI 10.1002/dmrr.3657
   Seidel D, 2020, BMJ OPEN, V10, DOI 10.1136/bmjopen-2018-026345
   Senneville É, 2023, CLIN INFECT DIS, DOI [10.1002/dmrr.3687, 10.1093/cid/ciad527]
   strobe-statement, STROBE-strengthening the reporting of observational studies in epidemiology
   van Netten JJ, 2024, DIABETES-METAB RES, V40, DOI 10.1002/dmrr.3654
   Wang AP, 2020, BURNS TRAUMA, V8, DOI 10.1093/burnst/tkaa017
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
   Yang L, 2022, WORLD J DIABETES, V13, P1014, DOI 10.4239/wjd.v13.i12.1014
   Zaver V., 2023, Statpearls
NR 28
TC 0
Z9 0
U1 1
U2 7
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD OCT 12
PY 2025
VL 14
IS 20
AR 7193
DI 10.3390/jcm14207193
PG 13
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 9AM9R
UT WOS:001601723600001
PM 41156063
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ragonese, A
   Malan, F
   Festa, P
   Giudice, G
   Papa, G
   Ciliberti, M
   Sciuto, A
   Sciattella, P
AF Ragonese, Angela
   Malan, Fabrizio
   Festa, Patrizio
   Giudice, Giuseppe
   Papa, Giovanni
   Ciliberti, Marino
   Sciuto, Antonio
   Sciattella, Paolo
TI Cost of treatment of hard-to-heal wounds in Italy: a study on real-world
   data
SO JOURNAL OF WOUND CARE
LA English
DT Article
DE continuity of care; cost of illness; dwell; hard-to-heal; health
   economics; instillation; negative pressure wound therapy; NPWTi-d;
   wound; wound care; wound dressing; wound healing
ID INSTILLATION THERAPY; SALINE; MANAGEMENT; DEVICES; RISK; CARE
AB Objective: To assess the clinical effectiveness and cost benefits of negative pressure wound therapy with instillation and dwell (NPWTi-d) compared to standard NPWT and other therapies in managing hard-to-heal wounds. Method: An observational, retrospective, multicentre study was conducted using data from three hospitals in Italy. Eligible patients included all adults discharged in 2021 with specific diagnoses related to hard-to-heal wounds. Data on healthcare resource use, including length of hospital stay (LoS), number of dressings used and procedures performed, were analysed. The economic evaluation estimated hospitalisation costs based on the average daily rate. The analysis findings were further examined in an expert meeting focused on assessing the impact of continuity of care pathways on treatment outcomes. Results: A total of 64 patients were enrolled: 38 received NPWT; 16 received NPWTi-d; and 10 received other treatments, including traditional and advanced wound care approaches. The NPWTi-d group demonstrated a significantly shorter average LoS (13.4 days) compared to the NPWT (23.6 days) and other treatments (21.5 days) groups. Patients receiving NPWTi-d also had fewer dressing changes (2.6) than those treated with NPWT (3.5) and other therapies (6.6). This reduction in resource consumption translates to cost savings of >& euro;6000 (-35.1%) per hospitalisation compared to the overall average hospitalisation cost across the study sample and & euro;7645 (-40.7%) compared to other treatments. The findings were confirmed during the expert meeting. Conclusion: As shown by the findings of this study, by improving patient outcomes and reducing the burden on healthcare systems, NPWTi-d should be considered a key component in modern wound care pathways. Its implementation aligns with current healthcare initiatives focused on optimising resource use and improving patient quality of life. Declaration of interest: This study was funded by Solventum, Milan, Italy, which is a manufacturer of medical devices, including NPWT systems. Solventum provided funding only and had no involvement in study design, data collection, analysis, manuscript writing, or the decision to publish. The authors have no conflicts of interest to declare.
C1 [Ragonese, Angela; Sciattella, Paolo] Univ Roma Tor Vergata, Econ Evaluat & HTA EEHTA CEIS, Rome, Italy.
   [Malan, Fabrizio] CTO Hosp, Citta Salute & Sci, Plast Surg Dept, Turin, Italy.
   [Festa, Patrizio] Cardarelli Hosp, Trauma Ctr Dept, Naples, Italy.
   [Giudice, Giuseppe] Univ Bari Aldo Moro, Dept Emergency & Organ Transplantat, Div Plast & Reconstruct Surg, Bari, Italy.
   [Papa, Giovanni] ASUGI Azienda Sanitaria Univ Giuliano Isontina, Osped Cattinara, Plast Surg Dept, Trieste, Italy.
   [Ciliberti, Marino] Ctr Aziendale Riparaz Tissutale, Wound Care Ctr, Castellammare Di Stabia, Italy.
   [Sciuto, Antonio] Cardarelli Hosp, Dept Gen Surg, Naples, Italy.
C3 University of Rome Tor Vergata; A.O.U. Citta della Salute e della
   Scienza di Torino; Antonio Cardarelli Hospital; Universita degli Studi
   di Bari Aldo Moro; Antonio Cardarelli Hospital
RP Ragonese, A (通讯作者)，Univ Roma Tor Vergata, Econ Evaluat & HTA EEHTA CEIS, Rome, Italy.
EM angelaragonese@gmail.com
CR Andrianello S, 2021, SURGERY, V169, P1069, DOI 10.1016/j.surg.2020.10.029
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Brinkert D, 2013, INT WOUND J, V10, P56, DOI 10.1111/iwj.12176
   Burke JR, 2014, SMART HOMECARE TECHN, V2, P129, DOI 10.2147/SHTT.S53413
   Chowdhry SA, 2019, PRS-GLOB OPEN, V7, DOI 10.1097/GOX.0000000000002087
   Collinsworth AW, 2022, WOUNDS, V34, P269, DOI 10.25270/wnds/22013
   Crumley C, 2021, J WOUND OSTOMY CONT, V48, P199, DOI 10.1097/WON.0000000000000760
   De Pellegrin L, 2023, INT WOUND J, V20, P2402, DOI 10.1111/iwj.14072
   Diehm YF, 2021, PLAST RECONSTR SURG, V147, p43S, DOI 10.1097/PRS.0000000000007610
   Eurostat, HEALTHCARE EXPENDITU
   Faust E, 2021, PLAST RECONSTR SURG, V147, p16S, DOI 10.1097/PRS.0000000000007607
   Fernández LG, 2024, ADV WOUND CARE, V13, P416, DOI 10.1089/wound.2023.0113
   Fluieraru S, 2013, J WOUND CARE, V22, P293, DOI 10.12968/jowc.2013.22.6.293
   Gabriel A., 2014, Eplasty, V14
   Gabriel A, 2021, PLAST RECONSTR SURG, V147, p68S, DOI 10.1097/PRS.0000000000007614
   Gabriel A, 2012, INT WOUND J, V9, P25, DOI 10.1111/j.1742-481X.2012.01014.x
   Giri P, 2021, ANN MED SURG, V61, P73, DOI 10.1016/j.amsu.2020.12.015
   Griffin LP, 2022, AM J MANAG CARE, V28, P53, DOI 10.37765/ajmc.2022.88738
   Gupta S, 2016, INT WOUND J, V13, P159, DOI 10.1111/iwj.12452
   Kahveci R, 2022, EPLASTY, V22, P60
   Kim PJ, 2022, INT WOUND J, V19, P888, DOI 10.1111/iwj.13689
   Kim PJ, 2021, PLAST RECONSTR SURG, V147, p27S, DOI 10.1097/PRS.0000000000007608
   Kim PJ, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9047
   Kim PJ, 2020, INT WOUND J, V17, P1194, DOI 10.1111/iwj.13424
   Kim PJ, 2020, INT WOUND J, V17, P174, DOI 10.1111/iwj.13254
   Lavery Lawrence A, 2007, Int Wound J, V4, P103, DOI 10.1111/j.1742-481X.2007.00317.x
   Lindholm C, 2016, INT WOUND J, V13, P5, DOI 10.1111/iwj.12623
   Ministero dell' Economia e delle Finanze, 2021, GREEN PAP PUBL SPEND
   Omar M, 2016, J WOUND CARE, V25, P475, DOI 10.12968/jowc.2016.25.8.475
   Pompeo M Q, 2001, Ostomy Wound Manage, V47, P65
   Queen D, 2024, INT WOUND J, V21, DOI 10.1111/iwj.14709
   R Core Team, 2017, R LANG ENV STAT COMP
   Silverman Ronald P, 2023, Eplasty, V23, pe54
   West JM, 2018, ADV WOUND CARE, V7, P333, DOI 10.1089/wound.2018.0793
   Zaver V, 2024, NEGATIVE PRESSURE WO
NR 35
TC 0
Z9 0
U1 0
U2 0
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD APR
PY 2026
VL 35
IS 4
BP 342
EP 348
PG 7
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA GF4ZE
UT WOS:001735159000001
PM 41926470
DA 2026-07-24
ER

PT J
AU Salem, HS
   Sherman, AE
   Chen, ZM
   Scuderi, GR
   Mont, MA
AF Salem, Hytham S.
   Sherman, Alain E.
   Chen, Zhongming
   Scuderi, Giles R.
   Mont, Michael A.
TI The Utility of Perioperative Products for the Prevention of Surgical
   Site Infections in Total Knee Arthroplasty and Lower Extremity
   Arthroplasty: A Systematic Review
SO JOURNAL OF KNEE SURGERY
LA English
DT Review
DE total knee arthroplasty; perioperative products; surgical site
   infections; Systematic Review
ID TOTAL JOINT ARTHROPLASTY; PRESSURE WOUND THERAPY; RESISTANT
   STAPHYLOCOCCUS-AUREUS; ORTHOPEDIC-SURGERY; TOTAL HIP; PREOPERATIVE
   DECOLONIZATION; BACTERIAL-CONTAMINATION; RISK-FACTORS; MAINTAINS
   NORMOTHERMIA; WARMING BLANKETS
AB Surgical site infections (SSIs) are among the most prevalent and devastating complications following lower extremity total joint arthroplasty (TJA). Strategies to reduce the rates can be divided into preoperative, perioperatives, and postoperative measures. A multicenter trial is underway to evaluate the efficacy of implementing a bundled care program for SSI prevention in lower extremity TJA including: (1) nasal decolonization; (2) surgical skin antisepsis; (3) antimicrobial incise draping; (4) temperature management; and (5) negative-pressure wound therapy for selected high-risk patients. The purposes of this systematic review were to provide a background and then to summarize the available evidence pertaining to each of these SSI-reduction strategies with special emphasis on total knee arthroplasty. A systematic review of the literature was conducted in accordance with the 2009 Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guidelines. Five individual literature searches were performed to identify studies evaluating nasal decolonization temperature management, surgical skin antisepsis, antimicrobial incise draping, and negative-pressure wound therapy. The highest level of evidence reports was used in each product review, and if there were insufficient arthroplasty papers on the particular topic, then papers were further culled from the surgical specialties to form the basis for the review. There was sufficient literature to assess all of the various prophylactic and preventative techniques. All five products used in the bundled program were supported for use as prophylactic agents or for the direct reduction of SSIs in both level I and II studies. This systematic review showed that various pre-, intra-, and postoperative strategies are efficacious in decreasing the risks of SSIs following lower extremity TJA procedures. Thus, including them in the armamentarium for SSI-reduction strategies for hip and knee arthroplasty surgeons should decrease the incidence of infections. We expect that the combined use of these products in an upcoming study will support these findings and may further enhance the reduction of total knee arthroplasty SSIs in a synergistic manner.
C1 [Salem, Hytham S.; Sherman, Alain E.; Chen, Zhongming; Scuderi, Giles R.; Mont, Michael A.] Northwell Hlth Orthopaed, Lenox Hill Hosp, 130 East 77th St,11th Floor, New York, NY 10075 USA.
   [Salem, Hytham S.; Chen, Zhongming; Mont, Michael A.] Sinai Hosp Baltimore, Ctr Joint Preservat & Replacement, Rubin Inst Adv Orthoped, Baltimore, MD USA.
C3 Northwell Health; Sinai Hospital of Baltimore
RP Mont, MA (通讯作者)，Northwell Hlth Orthopaed, Lenox Hill Hosp, 130 East 77th St,11th Floor, New York, NY 10075 USA.
EM rhondamont@aol.com
OI Chen, Zhongming/0000-0001-9647-7193
CR Abou Ghaddara H, 2020, AM J INFECT CONTROL, V48, P456, DOI 10.1016/j.ajic.2019.09.014
   Ackermann W, 2018, FRONT SURG, V5, DOI 10.3389/fsurg.2018.00064
   Albrecht Mark, 2009, Orthop Rev (Pavia), V1, pe28, DOI 10.4081/or.2009.e28
   ALEXANDER JW, 1985, ARCH SURG-CHICAGO, V120, P1357
   Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe276, DOI [10.1016/s1473-3099(16)30402-9, 10.1016/s1473-3099(16)30398-x, 10.1016/S1473-3099(16)30398-X]
   Allen MW, 2017, J ARTHROPLASTY, V32, P2307, DOI 10.1016/j.arth.2017.01.005
   Anatone Alex J, 2018, Arthroplast Today, V4, P493, DOI [10.1016/j.artd.2018.09.004, 10.1016/j.artd.2018.09.004]
   Anderson MJ, 2015, ANTIMICROB AGENTS CH, V59, P2765, DOI 10.1128/AAC.04624-14
   [Anonymous], 2009, BMJ-BRIT MED J, V21, P7, DOI [DOI 10.1136/bmj.b2535, 10.1371/journal.pmed.1000097, DOI 10.7326/0003-4819-151-4-200908180-00135]
   Baratz MD, 2015, CLIN ORTHOP RELAT R, V473, P2283, DOI 10.1007/s11999-015-4191-3
   Barie PS, 2005, SURG CLIN N AM, V85, P1115, DOI 10.1016/j.suc.2005.09.006
   Bebko SP, 2015, JAMA SURG, V150, P390, DOI 10.1001/jamasurg.2014.3480
   BENNETT J, 1994, BRIT J ANAESTH, V73, P180, DOI 10.1093/bja/73.2.180
   Benson EE, 2012, AM J NURS, V112, P26, DOI 10.1097/01.NAJ.0000414315.41460.bf
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Berti M, 1997, J CLIN ANESTH, V9, P482, DOI 10.1016/S0952-8180(97)00105-0
   Bibbo C, 2005, CLIN ORTHOP RELAT R, P204, DOI 10.1097/blo.0000167832.47464.22
   Blom A W, 2007, J Orthop Surg (Hong Kong), V15, P267
   Bode LGM, 2010, NEW ENGL J MED, V362, P9, DOI 10.1056/NEJMoa0808939
   BORMS SF, 1994, J CLIN ANESTH, V6, P303, DOI 10.1016/0952-8180(94)90077-9
   Bozic KJ, 2010, CLIN ORTHOP RELAT R, V468, P45, DOI 10.1007/s11999-009-0945-0
   Bozic KJ, 2009, J BONE JOINT SURG AM, V91A, P128, DOI 10.2106/JBJS.H.00155
   Brandt S, 2010, ANESTH ANALG, V110, P834, DOI 10.1213/ANE.0b013e3181cb3f5f
   Breitner S, 1986, Unfallchirurgie, V12, P301, DOI 10.1007/BF02585837
   Burns PB, 2011, PLAST RECONSTR SURG, V128, P305, DOI 10.1097/PRS.0b013e318219c171
   Caffrey AR, 2010, J HOSP INFECT, V76, P206, DOI 10.1016/j.jhin.2010.06.023
   Carroll K, 2014, CLIN MICROBIOL INFEC, V20, P130, DOI 10.1111/1469-0691.12209
   Casati A, 1999, Minerva Anestesiol, V65, P507
   Charehbili A, 2019, BJS OPEN, V3, P617, DOI 10.1002/bjs5.50177
   Chen AF, 2013, J ARTHROPLASTY, V28, P18, DOI 10.1016/j.arth.2013.03.036
   Cheng K, 2009, FOOT ANKLE INT, V30, P992, DOI 10.3113/FAI.2009.0992
   CHIU KY, 1993, AUST NZ J SURG, V63, P798, DOI 10.1111/j.1445-2197.1993.tb00343.x
   Cooper HJ, 2018, INJURY, V49, P386, DOI 10.1016/j.injury.2017.11.010
   Cooper HJ, 2016, J ARTHROPLASTY, V31, P1047, DOI 10.1016/j.arth.2015.11.010
   Curley AJ, 2018, ORTHOPEDICS, V41, pE837, DOI 10.3928/01477447-20181010-02
   FAIRCLOUGH JA, 1986, J INT MED RES, V14, P105, DOI 10.1177/030006058601400210
   Falk-Brynhildsen K, 2013, BIOL RES NURS, V15, P242, DOI 10.1177/1099800411430381
   Fanelli A, 2009, ANESTH ANALG, V108, P199, DOI 10.1213/ane.0b013e31818e6199
   FRENCH MLV, 1976, ANN SURG, V184, P46, DOI 10.1097/00000658-197607000-00008
   Giannini S, 2018, J WOUND CARE, V27, P520, DOI 10.12968/jowc.2018.27.8.520
   GILLIAM DL, 1990, CLIN ORTHOP RELAT R, P258
   Gow N, 2016, NEW ZEAL MED J, V129, P51
   Grabsch EA, 2004, ANZ J SURG, V74, P769, DOI 10.1111/j.1445-1433.2004.03154.x
   Gradl G, 2014, J BONE JOINT SURG AM, V96A, P223, DOI 10.2106/JBJS.L.01514
   Grove GL, 2012, J BONE JOINT SURG AM, V94A, P1187, DOI 10.2106/JBJS.K.00261
   Hacek DM, 2008, CLIN ORTHOP RELAT R, V466, P1349, DOI 10.1007/s11999-008-0210-y
   Hadley S, 2010, ARTHRITIS, DOI 10.1155/2010/924518
   Haeberle Heather S, 2017, Surg Technol Int, V31, P295
   Hanada M, 2020, EUR J ORTHOP SURG TR, V30, P917, DOI 10.1007/s00590-020-02653-y
   Harris JD, 2013, ARTHROSCOPY, V29, P589, DOI 10.1016/j.arthro.2012.11.003
   Helito CP, 2020, BMC MUSCULOSKEL DIS, V21, DOI 10.1186/s12891-020-03510-z
   Hemani Micah L, 2009, Rev Urol, V11, P190
   Hesselvig AB, 2020, CLIN ORTHOP RELAT R, V478, P1007, DOI 10.1097/CORR.0000000000001142
   Higuera-Rueda CA, 2021, J ARTHROPLASTY, V36, pS295, DOI 10.1016/j.arth.2021.02.076
   Hofmann KJ, 2017, CURR ORTHOP PRACT, V28, P66, DOI 10.1097/BCO.0000000000000454
   HOHN DC, 1976, SURG FORUM, V27, P18
   HUNT TK, 1972, SURG GYNECOL OBSTETR, V135, P561
   Izakovicova P, 2019, EFORT OPEN REV, V4, P482, DOI 10.1302/2058-5241.4.180092
   Jacobson C, 2005, CLIN ORTHOP RELAT R, P32, DOI 10.1097/01.blo.0000182245.29830.bc
   Jeans E, 2018, J INFECTION, V77, P405, DOI 10.1016/j.jinf.2018.05.012
   Kalmeijer MD, 2002, CLIN INFECT DIS, V35, P353, DOI 10.1086/341025
   Kapadia BH, 2016, LANCET, V387, P386, DOI 10.1016/S0140-6736(14)61798-0
   Karlakki SL, 2016, BONE JOINT RES, V5, P328, DOI 10.1302/2046-3758.58.BJR-2016-0022.R1
   Keeney JA, 2019, J ARTHROPLASTY, V34, P723, DOI 10.1016/j.arth.2018.12.008
   Kim DH, 2010, J BONE JOINT SURG AM, V92A, P1820, DOI 10.2106/JBJS.I.01050
   Kim HY, 2014, KOREAN J ANESTHESIOL, V66, P352, DOI 10.4097/kjae.2014.66.5.352
   Kim JH, 2019, J ARTHROPLASTY, V34, P2804, DOI 10.1016/j.arth.2019.06.020
   Kirkland KB, 1999, INFECT CONT HOSP EP, V20, P725, DOI 10.1086/501572
   Koc BB, 2017, ORTHOP NURS, V36, P356, DOI 10.1097/NOR.0000000000000383
   Kong HH, 2012, J INVEST DERMATOL, V132, P933, DOI 10.1038/jid.2011.417
   Kuo FC, 2021, J ARTHROPLASTY, V36, P2612, DOI 10.1016/j.arth.2021.02.047
   Kuo FC, 2020, J ARTHROPLASTY, V35, P1686, DOI 10.1016/j.arth.2020.01.050
   Kurtz S, 2007, J BONE JOINT SURG AM, V89A, P780, DOI 10.2106/JBJS.F.00222
   Kurtz SM, 2012, J ARTHROPLASTY, V27, P61, DOI 10.1016/j.arth.2012.02.022
   Kurz A, 1996, NEW ENGL J MED, V334, P1209, DOI 10.1056/NEJM199605093341901
   KURZ A, 1993, ANESTH ANALG, V77, P89
   Legg AJ, 2013, BONE JOINT J, V95B, P407, DOI 10.1302/0301-620X.95B3.29121
   Legg AJ, 2012, J BONE JOINT SURG BR, V94B, P254, DOI 10.1302/0301-620X.94B2.27562
   Lehtinen SJ, 2010, ANN SURG, V252, P696, DOI 10.1097/SLA.0b013e3181f6c2a9
   Lenguerrand E, 2017, BMJ OPEN, V7, DOI 10.1136/bmjopen-2016-014056
   Letzelter J, 2019, J AM ACAD ORTHOP SUR, V27, P599, DOI 10.5435/JAAOS-D-18-00105
   Li Cheng, 2018, Hip Pelvis, V30, P138, DOI [10.5371/hp.2018.30.3.138, 10.5371/hp.2018.30.3.138]
   Lindsay William, 2011, J Perioper Pract, V21, P206
   Loftus RW, 2020, JAMA NETW OPEN, V3, DOI 10.1001/jamanetworkopen.2020.1934
   Lum ZC, 2018, J ARTHROPLASTY, V33, P3783, DOI 10.1016/j.arth.2018.08.021
   Mahoney C B, 1999, AANA J, V67, P155
   Manoharan V, 2016, J ARTHROPLASTY, V31, P2487, DOI 10.1016/j.arth.2016.04.016
   Maslow J, 2014, ORTHOPEDICS, V37, pE576, DOI 10.3928/01477447-20140528-59
   Matar WY, 2010, J BONE JOINT SURG AM, V92A, P36, DOI 10.2106/JBJS.J.01046
   McClain R, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.11474
   McGovern PD, 2011, J BONE JOINT SURG BR, V93B, P1537, DOI 10.1302/0301-620X.93B11.27124
   Merle V, 2000, AM J INFECT CONTROL, V28, P109
   Milandt N, 2016, ACTA ORTHOP, V87, P380, DOI 10.1080/17453674.2016.1180577
   Moretti B, 2009, J HOSP INFECT, V73, P58, DOI 10.1016/j.jhin.2009.06.006
   Moroski NM, 2015, J ARTHROPLASTY, V30, P444, DOI 10.1016/j.arth.2014.10.017
   Morrison TN, 2016, J ARTHROPLASTY, V31, P1289, DOI 10.1016/j.arth.2015.12.009
   Namba RS, 2013, J BONE JOINT SURG AM, V95A, P775, DOI 10.2106/JBJS.L.00211
   Newman JM, 2019, J ARTHROPLASTY, V34, P554, DOI 10.1016/j.arth.2018.11.017
   Ng SF, 2003, ANESTH ANALG, V96, P171, DOI 10.1097/00000539-200301000-00036
   Ng V, 2006, ANAESTHESIA, V61, P1100, DOI 10.1111/j.1365-2044.2006.04816.x
   NOBLE WC, 1965, BRIT J EXP PATHOL, V46, P254
   Obamuyide H. A., 2015, East and Central African Journal of Surgery, V20, P80
   Occhipinti LL, 2013, CAN VET J, V54, P1157
   Oguz R, 2017, J CLIN ANESTH, V38, P160, DOI 10.1016/j.jclinane.2017.02.008
   Ostrander RV, 2005, J BONE JOINT SURG AM, V87A, P980, DOI 10.2106/JBJS.D.01977
   Pachowsky M, 2012, INT ORTHOP, V36, P719, DOI 10.1007/s00264-011-1321-8
   Pauser J, 2016, INT WOUND J, V13, P663, DOI 10.1111/iwj.12344
   Peel TN, 2019, CLIN MICROBIOL INFEC, V25, P1239, DOI 10.1016/j.cmi.2019.06.016
   Pelfort X, 2019, ACTA ORTHOP TRAUMATO, V53, P426, DOI 10.1016/j.aott.2019.08.014
   Peng HM, 2018, BRAZ J MED BIOL RES, V51, DOI [10.1590/1414-431X20176736, 10.1590/1414-431x20176736]
   Percival SL, 2012, INT WOUND J, V9, P14, DOI 10.1111/j.1742-481X.2011.00836.x
   Phillips M, 2014, INFECT CONT HOSP EP, V35, P826, DOI 10.1086/676872
   Pietrzak JRT, 2020, J ORTHOP SURG RES, V15, DOI 10.1186/s13018-020-01635-4
   Premkumar A, 2021, J ARTHROPLASTY, V36, P1484, DOI 10.1016/j.arth.2020.12.005
   Rao N, 2008, CLIN ORTHOP RELAT R, V466, P1343, DOI 10.1007/s11999-008-0225-4
   Rao N, 2011, J ARTHROPLASTY, V26, P1501, DOI 10.1016/j.arth.2011.03.014
   Redfern RE, 2017, J ARTHROPLASTY, V32, P3333, DOI 10.1016/j.arth.2017.06.019
   Rezapoor M, 2018, J ARTHROPLASTY, V33, P1891, DOI 10.1016/j.arth.2018.01.013
   Rezapoor M, 2017, J ARTHROPLASTY, V32, P2815, DOI 10.1016/j.arth.2017.04.039
   Ridgeway S, 2005, J BONE JOINT SURG BR, V87B, P844, DOI 10.1302/0301-620X.87B6.15121
   Rieser GR, 2018, J ARTHROPLASTY, V33, P1652, DOI 10.1016/j.arth.2018.01.033
   RITTER MA, 1988, CLIN ORTHOP RELAT R, P307
   Saidel L, 2020, INFECT CONT HOSP EP, V41, pS386, DOI 10.1017/ice.2020.1021
   Saltzman MD, 2009, J BONE JOINT SURG AM, V91A, P1949, DOI 10.2106/JBJS.H.00768
   Sandoval MF, 2017, PATIENT SAF SURG, V11, DOI 10.1186/s13037-017-0126-0
   Sankar B, 2005, INT ORTHOP, V29, P160, DOI 10.1007/s00264-005-0649-3
   Savage JW, 2012, J BONE JOINT SURG AM, V94A, P490, DOI 10.2106/JBJS.K.00471
   Scheidt S, 2020, J ARTHROPLASTY, V35, P2595, DOI 10.1016/j.arth.2020.05.012
   Schmied H, 1996, LANCET, V347, P289, DOI 10.1016/S0140-6736(96)90466-3
   Scott E.M., 2001, AORN J, V73, P921, DOI [10.1016/s0001-2092(06)61744-4, 10.1016/S0001-2092(06)61744-4, DOI 10.1016/S0001-2092(06)61744-4]
   Scott R.D., 2009, The direct medical costs of healthcare associated infections in US hospitals and the benefits of prevention
   SESSLER DI, 1991, ANESTHESIOLOGY, V75, P594, DOI 10.1097/00000542-199110000-00009
   Shiroky J, 2020, SURGERY, V167, P1001, DOI 10.1016/j.surg.2020.01.018
   Sloan M, 2018, J BONE JOINT SURG AM, V100, P1455, DOI 10.2106/JBJS.17.01617
   Sousa RJG, 2016, J ARTHROPLASTY, V31, P234, DOI 10.1016/j.arth.2015.08.003
   Sporer SM, 2016, J ARTHROPLASTY, V31, pS144, DOI 10.1016/j.arth.2016.05.019
   Springer Bryan D, 2017, Arthroplast Today, V3, P137, DOI [10.1016/j.artd.2017.05.003, 10.1016/j.artd.2017.05.003]
   Stambough JB, 2017, J ARTHROPLASTY, V32, P728, DOI 10.1016/j.arth.2016.09.041
   Su WC, 2021, J CLIN MED, V10, DOI 10.3390/jcm10030434
   Teo BJX, 2018, J ORTHOP SURG-HONG K, V26, DOI 10.1177/2309499018785647
   Tjoakarfa C, 2017, J ARTHROPLASTY, V32, P624, DOI 10.1016/j.arth.2016.07.015
   Torres EG, 2016, J ARTHROPLASTY, V31, P215, DOI 10.1016/j.arth.2015.09.030
   Trentman TL, 2009, CAN J ANAESTH, V56, P914, DOI 10.1007/s12630-009-9199-2
   Tumia N, 2002, J HOSP INFECT, V52, P171, DOI 10.1053/jhin.2002.1297
   Tyagi V, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.7394
   Tyagi V, 2019, ORTHOPEDICS, V42, pE539, DOI 10.3928/01477447-20190906-06
   Urias DS, 2018, EUR J TRAUMA EMERG S, V44, P787, DOI 10.1007/s00068-017-0896-1
   Urish KL, 2016, CLIN ORTHOP RELAT R, V474, P1649, DOI 10.1007/s11999-016-4720-8
   Verra Wiebe Christiaan, 2018, Asian J Anesthesiol, V56, P128, DOI 10.6859/aja.201812_56(4).0002
   Webster J, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006353.pub4
   Whitehouse JD, 2002, INFECT CONT HOSP EP, V23, P183, DOI 10.1086/502033
   Wilcox MH, 2003, J HOSP INFECT, V54, P196, DOI 10.1016/S0195-6701(03)00147-6
   Winkler M, 2000, ANESTH ANALG, V91, P978, DOI 10.1097/00000539-200010000-00039
   Wolford HM, 2018, INFECT CONT HOSP EP, V39, P1189, DOI 10.1017/ice.2018.184
   Xu Peter Z, 2017, Hand (N Y), V12, P258, DOI [10.1177/1558944716658856, 10.1177/1558944716658856]
   Yang G, 2020, MEDICINE, V99, DOI 10.1097/MD.0000000000019283
   Zmistowski B, 2013, J BONE JOINT SURG AM, V95A, P2177, DOI 10.2106/JBJS.L.00789
NR 157
TC 4
Z9 5
U1 0
U2 6
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA Oswald-Hesse-Strasse 50, D-70469 STUTTGART, GERMANY
SN 1538-8506
EI 1938-2480
J9 J KNEE SURG
JI J. Knee Surg.
PD JUL
PY 2022
VL 35
IS 09
BP 1023
EP 1043
DI 10.1055/s-0041-1740394
EA DEC 2021
PG 21
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 3P8NG
UT WOS:000727677200001
PM 34875715
DA 2026-07-24
ER

PT J
AU Daryapeyma, A
   Nilsson, O
   Pettersson, J
   Stackelberg, O
   Torbjörnsson, E
   Hultgren, R
AF Daryapeyma, Alireza
   Nilsson, Olga
   Pettersson, Jennifer
   Stackelberg, Otto
   Torbjornsson, Eva
   Hultgren, Rebecka
TI Prophylactic use of incisional negative pressure wound therapy for groin
   incisions in vascular surgery: randomized clinical trial
SO BJS OPEN
LA English
DT Article
ID SURGICAL SITE INFECTION; LOWER-EXTREMITY REVASCULARIZATION;
   QUALITY-OF-LIFE; RISK-FACTORS; COMPLICATIONS; MULTICENTER; VALIDATION;
   PREVENTION; EXPERIENCE; MANAGEMENT
AB Background: The efficacy of incisional negative pressure wound therapy (iNPWT) in preventing surgical site infections (SSIs) after infrainguinal vascular surgery remains unclear. This study compared iNPWT with standard gauze dressings to determine the effects on SSI incidence and quality of life. Methods: Patients undergoing infrainguinal vascular surgery were recruited to a regional randomized clinical trial. All patients had a groin incision for either thromboendarterectomy only with a vein or synthetic patch or hybrid procedures with thromboendarterectomy and concurrent endovascular treatment. The control and intervention groups received sterile gauze and iNPWT dressings, respectively. The primary endpoint was the incidence of SSIs within 30 days, measured using the Additional treatment, Serous discharge, Erythema, Purulent exudates, Separation of the deep tissues, Isolation of bacteria and inpatient Stay (ASEPSIS) scoring protocol. Secondary endpoints were scores on the Wound Quality of Life and EQ-5D (TM) three-level (EQ-5D-3L (TM)) questionnaires. Results: Of the 123 patients randomized, 109 (89%) completed the study. The incidence of SSI was similar in the intervention and control groups (15% versus 25%, respectively; P = 0.340), but was higher in patients with a body mass index (BMI) >= 25 kg/m2 than in those with a BMI < 25 kg/m2 (52% versus 21%, respectively). Wound Quality of Life mean scores were similar in the control and intervention groups (10.60 versus 12.85, respectively; P = 0.322); however, the intervention group reported a larger negative impact on everyday life than the control group (7.40 versus 4.91 for the everyday life domain, respectively; P = 0.048). There were no significant differences between the two groups in EQ-5D-3L (TM) scores. Conclusion: The similar distribution of SSIs regardless of the type of wound dressing, in addition to the negative impact on everyday life, does not support the general use of iNPWT in this or similar patient cohorts. The unique aspect of this trial is the patient perspective on the use of iNPWT, revealing a divergence between the views of patients and healthcare providers regarding optimal wound care. In the setting of individualized care, there may be a place for iNPWT in selected patients with a high BMI and excessive perioperative bleeding, which are associated with a higher SSI risk.
C1 [Daryapeyma, Alireza; Nilsson, Olga; Hultgren, Rebecka] Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden.
   [Daryapeyma, Alireza; Nilsson, Olga; Hultgren, Rebecka] Karolinska Univ Hosp, Dept Vasc Surg, Stockholm, Sweden.
   [Pettersson, Jennifer] Liljeholmen Univ Primary Hlth Care Ctr, Stockholm, Sweden.
   [Stackelberg, Otto; Torbjornsson, Eva] Karolinska Inst, Dept Clin Sci & Educ, Sodersjukhuset, Stockholm, Sweden.
   [Torbjornsson, Eva] Stockholm South Gen Hosp, Dept Surg, Stockholm, Sweden.
C3 Karolinska Institutet; Karolinska Institutet; Karolinska University
   Hospital; Karolinska Institutet; Sodersjukhuset Hospital
RP Hultgren, R (通讯作者)，Karolinska Inst, Karolinska Univ Hosp A8 01, Dept Vasc Surg, S-17176 Stockholm, Sweden.
EM rebecka.hultgren@ki.se
RI Torbjörnsson, Eva/DTM-3611-2022; Hultgren, Rebecka/K-8738-2012; Nilsson,
   Olga/LRT-7525-2024
OI Torbjörnsson, Eva/0000-0003-0720-4981; Stackelberg,
   Otto/0000-0002-5748-9113; Hultgren, Rebecka/0000-0002-8869-0493;
   Nilsson, Olga/0000-0002-7670-1677
FU Swedish Heart-Lung Foundation [20160266, 20220282]; Regional agreement
   on medical training and clinical research [ALF: FoUI-960079]; Stockholm
   County Council; Karolinska Institutet (Hultgren); Capio Research
   Foundation [20193241]
FX This study was supported by the Swedish Heart-Lung Foundation (grant
   numbers 20160266, 20220282), by the Regional agreement on medical
   training and clinical research (ALF: FoUI-960079) between Stockholm
   County Council and Karolinska Institutet (Hultgren) and Capio Research
   Foundation (grant number 20193241). All authors declare independence
   from funders.
CR Aeschbacher P, 2021, FRONT SURG, V8, DOI 10.3389/fsurg.2021.656249
   Anderson DJ, 2011, INFECT DIS CLIN N AM, V25, P135, DOI 10.1016/j.idc.2010.11.004
   ARBEIT RD, 1987, J INFECT DIS, V156, P947, DOI 10.1093/infdis/156.6.947
   Augustin M, 2017, WOUND REPAIR REGEN, V25, P852, DOI 10.1111/wrr.12583
   Benrashid E, 2020, J VASC SURG, V71, P896, DOI 10.1016/j.jvs.2019.05.066
   Bertges DJ, 2021, J VASC SURG, V74, P257, DOI 10.1016/j.jvs.2020.12.100
   Boll G, 2022, J VASC SURG, V75, P2086, DOI 10.1016/j.jvs.2021.12.070
   Cater JE, 2015, MED ENG PHYS, V37, P121, DOI 10.1016/j.medengphy.2014.07.011
   Chang JK, 2003, ANN VASC SURG, V17, P91, DOI 10.1007/s10016-001-0337-8
   Daryapeyma A, 2016, EUR J VASC ENDOVASC, V51, P690, DOI 10.1016/j.ejvs.2015.12.016
   Davis FM, 2017, J VASC SURG, V65, P1769, DOI 10.1016/j.jvs.2016.11.053
   de Lissovoy G, 2009, AM J INFECT CONTROL, V37, P387, DOI 10.1016/j.ajic.2008.12.010
   Dosluoglu HH, 2010, J VASC SURG, V51, P1160, DOI 10.1016/j.jvs.2009.11.053
   Fagerdahl AM, 2018, OSTOMY WOUND MANAG, V64, P40, DOI 10.25270/owm.2018.5.4046
   Fagerdahl AM, 2013, WOUNDS, V25, P205
   Groenen H, 2023, ECLINICALMEDICINE, V62, DOI 10.1016/j.eclinm.2023.102105
   Gwilym BL, 2021, EUR J VASC ENDOVASC, V62, P258, DOI 10.1016/j.ejvs.2021.05.009
   Hasselmann J, 2020, ANN SURG, V271, P48, DOI 10.1097/SLA.0000000000003364
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Inui T, 2015, SEMIN VASC SURG, V28, P201, DOI 10.1053/j.semvascsurg.2016.02.002
   Kasten K, 2025, VASCULAR, V33, P456, DOI 10.1177/17085381241247098
   Kent RC, 1996, SURGERY, V119, P378
   Kirkham AM, 2024, EUR J VASC ENDOVASC, V67, P455, DOI 10.1016/j.ejvs.2023.10.038
   Koncar I, 2016, VOJNOSANIT PREGL, V73, P9, DOI 10.2298/VSP13122212K
   Kuy S, 2014, ANN VASC SURG, V28, P53, DOI 10.1016/j.avsg.2013.08.002
   Lee E S, 2000, Surg Infect (Larchmt), V1, P257, DOI 10.1089/109629600750067183
   Lorenzo LR, 2024, EUR J VASC ENDOVASC, V68, P238, DOI 10.1016/j.ejvs.2024.04.031
   Mangram AJ, 1999, AM J INFECT CONTROL, V27, P97, DOI 10.1016/S0196-6553(99)70088-X
   Matatov T, 2013, J VASC SURG, V57, P791, DOI 10.1016/j.jvs.2012.09.037
   Nolan MB, 2017, JAMA SURG, V152, P476, DOI 10.1001/jamasurg.2016.5704
   Nordanstig J, 2024, EUR J VASC ENDOVASC, V67, P9, DOI 10.1016/j.ejvs.2023.08.067
   Norman G, 2022, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub7
   Pesonen LO, 2018, ANN VASC SURG, V46, P127, DOI 10.1016/j.avsg.2017.07.009
   Pherson MJ, 2022, J VASC SURG, V76, P1014, DOI 10.1016/j.jvs.2022.04.040
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Rabin R, 2001, ANN MED, V33, P337, DOI 10.3109/07853890109002087
   Rezk F, 2024, J VASC SURG, V79, DOI 10.1016/j.jvs.2023.11.043
   Sealed Envelope Ltd, Power Calculator for Binary Outcome Superiority Trial
   Svensson-Björk R, 2019, BJS-BRIT J SURG, V106, P310, DOI 10.1002/bjs.11100
   Totty JP, 2021, INT WOUND J, V18, P261, DOI 10.1111/iwj.13526
   Turtiainen J, 2010, SCAND J SURG, V99, P167, DOI 10.1177/145749691009900312
   Turtiainen J, 2012, WORLD J SURG, V36, P2528, DOI 10.1007/s00268-012-1655-4
   Vogel TR, 2010, J VASC SURG, V51, P122, DOI 10.1016/j.jvs.2009.08.006
   Vriesendorp TM, 2004, EUR J VASC ENDOVASC, V28, P520, DOI 10.1016/j.ejvs.2004.08.006
   WILSON APR, 1986, LANCET, V1, P311
   World Health Organization (WHO), 2015, WHO Surgical Site Infection Prevention Guidelines
   Zhao AH, 2022, ANN VASC SURG, V78, P336, DOI 10.1016/j.avsg.2021.06.045
NR 47
TC 3
Z9 4
U1 0
U2 0
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 2474-9842
J9 BJS OPEN
JI BJS Open
PD JUN
PY 2025
VL 9
IS 3
AR zraf059
DI 10.1093/bjsopen/zraf059
PG 8
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 3QZ3T
UT WOS:001506926600001
PM 40500745
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Zhao, AH
   Kwok, CHR
   Jansen, SJ
AF Zhao, Adam Hanting
   Kwok, Chi Ho Ricky
   Jansen, Shirley Jane
TI How to Prevent Surgical Site Infection in Vascular Surgery: A Review of
   the Evidence
SO ANNALS OF VASCULAR SURGERY
LA English
DT Review
ID GREAT SAPHENOUS-VEIN; RECONSTRUCTIVE ARTERIAL-SURGERY; RANDOMIZED
   CONTROLLED-TRIAL; NEGATIVE-PRESSURE THERAPY; PREOPERATIVE HAIR REMOVAL;
   LOWER-EXTREMITY BYPASS; WOUND-INFECTION; ANTIBIOTIC-PROPHYLAXIS;
   RISK-FACTORS; ANTIMICROBIAL PROPHYLAXIS
AB Background: This review aims to identify and review the current evidence for preventing postoperative surgical site infections in abdominal aortic aneurysm surgery or infrainguinal arterial surgery.
   Methods: Extended literature review of clinical trials that examined the prevention of postoperative surgical site infections in abdominal aortic aneurysm or infrainguinal arterial surgery. Searches were conducted on Ovid MEDLINE (1950 - 13 March 2020) using key terms for vascular surgery, surgical site infections and specific preventative techniques. Articles were included if they discussed a relationship between a preventative technique and surgical site infections in abdominal aortic aneurysm or infrainguinal arterial surgery. The GRADE guidelines were used to assess the quality of evidence.
   Results: 21 techniques and 81 studies were included. Prophylactic antibiotics and negative pressure wound therapy have a high quality of evidence for the prevention of surgical site infections in abdominal aortic aneurysm or infrainguinal arterial surgery. A moderate quality evidence base was identified for gentamicin containing collagen implant (confined to high surgical site infection risk centers). Currently, there is a low or very low quality of evidence to suggest a reduction in the surgical site infection rate for combination therapy, glycaemic control, Methicillin-resistant Staphylococcus aureus screening and absorbable suture. Evidence suggests no beneficial effect for nutritional supplementation, chlorhexidine bath, hair removal therapy, Staphylococcus aureus nasal eradication, cyanoacrylate microsealant, silver grafts, rifampicin bonded grafts, triclosan coated suture and postoperative wound drains. Endoscopic saphenous vein harvest may reduce surgical site infection rate (very low quality of evidence) but may lower long-term patency. Autologous vein grafts may increase surgical site infections (very low quality of evidence) but may provide better long-term patency rates in above-knee infrainguinal bypass surgery. There was no identified evidence for perioperative normother mia, electrosurgical bipolar vessel sealer or Dermabond and Tegaderm for surgical site infection prevention in vascular surgery.
   Conclusions: Prophylactic antibiotics and postoperative negative pressure wound therapy are effective in the prevention of postoperative surgical site infection in abdominal aortic aneurysm or infrainguinal arterial surgery. There exists a significant risk of bias in the literature for many preventative techniques and further studies are required to investigate the efficacy of gentamicin containing collagen implant, and specific combination therapies.
C1 [Zhao, Adam Hanting; Jansen, Shirley Jane] Univ Western Australia, Sch Med, Fac Hlth & Med Sci, Mailbox Drop Point 509,35 Stirling Hwy, Nedlands, WA 6009, Australia.
   [Zhao, Adam Hanting; Kwok, Chi Ho Ricky; Jansen, Shirley Jane] Sir Charles Gairdner Hosp, Dept Vasc & Endovasc Surg, Nedlands, WA, Australia.
   [Jansen, Shirley Jane] Curtin Univ, Fac Hlth Sci, Curtin Med Sch, Perth, WA, Australia.
   [Jansen, Shirley Jane] Harry Perkins Inst Med Res, Heart & Vasc Res Inst, Nedlands, WA, Australia.
C3 University of Western Australia; Sir Charles Gairdner Hospital;
   University of Western Australia; Curtin University; Harry Perkins
   Institute of Medical Research
RP Zhao, AH (通讯作者)，Univ Western Australia, Sch Med, Fac Hlth & Med Sci, Mailbox Drop Point 509,35 Stirling Hwy, Nedlands, WA 6009, Australia.; Zhao, AH (通讯作者)，Sir Charles Gairdner Hosp, QEII Med Ctr, Dept Vasc & Endovasc Surg, Level 4,A Block, Nedlands, WA 6009, Australia.
EM adam.zhao@health.wa.gov.au
RI /AGR-4157-2022; Jansen, Shirley/AAU-3889-2021
OI Zhao, Adam/0000-0002-4764-2508; Jansen, Shirley/0000-0001-7781-4748
CR Abouzari M, 2009, SURG NEUROL, V71, P261, DOI 10.1016/j.surneu.2008.01.059
   Aicher B, 2017, J VASC NURS, V35, P146, DOI 10.1016/j.jvn.2017.03.002
   ALEXANDER JW, 1983, ARCH SURG-CHICAGO, V118, P347
   Ambler GK, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001487.pub3
   Antoniou GA, 2019, J VASC SURG, V70, P1700, DOI 10.1016/j.jvs.2019.01.083
   Bak J, 2017, ANN VASC SURG, V43, P197, DOI 10.1016/j.avsg.2016.11.011
   BALTHAZAR ER, 1982, SOUTHERN MED J, V75, P799, DOI 10.1097/00007611-198207000-00006
   Beattie AH, 2000, GUT, V46, P813, DOI 10.1136/gut.46.6.813
   Bending M, 1996, J AM SOC NEPHROL, V7, P2403
   BRANCHEREAU A, 1987, PRESSE MED, V16, P1633
   BRANDBERG A, 1981, SKIN MICROBIOLOGY RE, P98
   Brookes JDL, 2020, INT J LOW EXTR WOUND, V19, P27, DOI 10.1177/1534734619876779
   Cadwallader RA, 2009, VASC ENDOVASC SURG, V43, P561, DOI 10.1177/1538574409334133
   CHESTER JF, 1983, ANN ROY COLL SURG, V65, P389
   CHRISTENSON JT, 1981, SCAND J INFECT DIS, V13, P51, DOI 10.1080/00365548.1981.11690367
   Coello R, 2005, J HOSP INFECT, V60, P93, DOI 10.1016/j.jhin.2004.10.019
   Court-Brown C M, 1981, J R Coll Surg Edinb, V26, P238
   D'Addato M, 1996, Cardiovasc Surg, V4, P200, DOI 10.1016/0967-2109(96)82315-5
   D'Addato M, 1997, EUR J VASC ENDOVASC, V14, P15, DOI 10.1016/S1078-5884(97)80146-3
   de Jonge SW, 2020, LANCET INFECT DIS, V20, P1182, DOI [10.1016/51473-3099(20)30084-0, 10.1016/S1473-3099(20)30084-0]
   de Jonge SW, 2017, MEDICINE, V96, DOI 10.1097/MD.0000000000006903
   Dua A, 2014, J VASC SURG, V60, P1635, DOI 10.1016/j.jvs.2014.08.072
   DUNLOP MG, 1990, BRIT J SURG, V77, P562, DOI 10.1002/bjs.1800770532
   Earnshaw J J, 1989, Eur J Vasc Surg, V3, P323, DOI 10.1016/S0950-821X(89)80068-4
   EARNSHAW JJ, 1988, ANN ROY COLL SURG, V70, P139
   Earnshaw JJ, 2000, BRIT J SURG, V87, P758, DOI 10.1046/j.1365-2168.2000.01490.x
   Eid RE, 2014, J VASC SURG, V59, P136, DOI 10.1016/j.jvs.2013.06.072
   Engelhardt M, 2018, INT WOUND J, V15, P327, DOI 10.1111/iwj.12848
   Estívariz CF, 2008, JPEN-PARENTER ENTER, V32, P389, DOI 10.1177/0148607108317880
   Fakhoury E, 2019, ANN VASC SURG, V60, P463, DOI 10.1016/j.avsg.2019.03.017
   Fawley WN, 2006, J HOSP INFECT, V62, P327, DOI 10.1016/j.jhin.2005.09.022
   Fernández-Prada M, 2017, ANN VASC SURG, V41, P160, DOI 10.1016/j.avsg.2016.09.038
   Franklin J, 2018, J VASC NURS, V36, P8, DOI 10.1016/j.jvn.2017.09.002
   Giles KA, 2010, ANN VASC SURG, V24, P48, DOI 10.1016/j.avsg.2009.05.003
   Goëau-Brissonnière O, 2011, ANN VASC SURG, V25, P134, DOI 10.1016/j.avsg.2010.09.002
   Gombert A, 2018, EUR J VASC ENDOVASC, V56, P442, DOI 10.1016/j.ejvs.2018.05.018
   Graling PR, 2013, AORN J, V97, P547, DOI 10.1016/j.aorn.2013.02.009
   Greenblatt DY, 2011, J VASC SURG, V54, P433, DOI 10.1016/j.jvs.2011.01.034
   Grober ED, 2013, J SEX MED, V10, P589, DOI 10.1111/j.1743-6109.2012.02904.x
   Hall JC, 1998, AM J SURG, V175, P87, DOI 10.1016/S0002-9610(97)00270-5
   HASSELGREN PO, 1984, ANN SURG, V200, P86
   Hasselmann J, 2020, ANN SURG, V271, P48, DOI 10.1097/SLA.0000000000003364
   Hawn MT, 2013, JAMA SURG, V148, P649, DOI 10.1001/jamasurg.2013.134
   HEALY DA, 1989, J VASC SURG, V10, P166, DOI 10.1067/mva.1989.0100166
   Healy D, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011111.pub2
   Hekman KE, 2019, J AM COLL SURGEONS, V228, P44, DOI 10.1016/j.jamcollsurg.2018.10.002
   Hirashima F, 2012, J VASC SURG, V56, P396, DOI 10.1016/j.jvs.2012.01.026
   Holdsworth J, 1999, ANN ROY COLL SURG, V81, P166
   HORCH R, 1989, VASA-J VASCULAR DIS, V18, P30
   Humbarger O, 2019, J VASC SURG, V70, P1514, DOI 10.1016/j.jvs.2019.02.046
   Hussain ST, 2012, INT J SURG, V10, pS5, DOI 10.1016/j.ijsu.2012.05.015
   Inui T, 2015, SEMIN VASC SURG, V28, P201, DOI 10.1053/j.semvascsurg.2016.02.002
   JENSEN LJ, 1985, THORAC CARDIOV SURG, V33, P300, DOI 10.1055/s-2007-1014145
   Jorgensen L G, 1991, Eur J Vasc Surg, V5, P87, DOI 10.1016/S0950-821X(05)80933-8
   KAISER AB, 1978, ANN SURG, V188, P283, DOI 10.1097/00000658-197809000-00003
   Kalish JA, 2014, J VASC SURG, V60, P1238, DOI 10.1016/j.jvs.2014.05.012
   Khan SZ, 2016, J VASC SURG, V63, P1546, DOI 10.1016/j.jvs.2016.01.032
   KO W, 1992, ANN THORAC SURG, V53, P301, DOI 10.1016/0003-4975(92)91337-9
   Kronick M, 2019, J VASC SURG, V70, P1534, DOI 10.1016/j.jvs.2019.02.043
   Kwon J, 2018, J VASC SURG, V68, P1744, DOI 10.1016/j.jvs.2018.05.224
   Langenberg JCM, 2016, PLOS ONE, V11, DOI 10.1371/journal.pone.0161058
   Langenberg JCM, 2018, SURG INFECT, V19, P510, DOI 10.1089/sur.2018.029
   Larena-Avellaneda A, 2009, J VASC SURG, V50, P790, DOI 10.1016/j.jvs.2009.05.003
   Lee K, 2017, J VASC SURG, V66, P1814, DOI 10.1016/j.jvs.2017.06.084
   Legendre C, 2008, J VASC SURG, V48, P688, DOI 10.1016/j.jvs.2008.04.012
   LORENTZEN JE, 1985, SURGERY, V98, P81
   LYNCH W, 1992, J HOSP INFECT, V21, P179, DOI 10.1016/0195-6701(92)90074-V
   Malde DJ, 2006, INT ANGIOL, V25, P204
   Miani S, 1982, Arch Sci Med (Torino), V139, P429
   Mirza AK, 2018, J VASC SURG, V67, P1199, DOI 10.1016/j.jvs.2017.08.084
   Nikulainen V, 2019, SURG INFECT, V20, P45, DOI 10.1089/sur.2018.202
   O'Brien R, 2011, SURG-J R COLL SURG E, V9, P245, DOI 10.1016/j.surge.2010.10.005
   OOSTVOGEL HJM, 1987, ACTA CHIR SCAND, V153, P571
   Parizh D, 2018, VASCULAR, V26, P47, DOI 10.1177/1708538117719155
   Patrick S, 2010, VASC ENDOVASC SURG, V44, P521, DOI 10.1177/1538574410373837
   Cebrián JP, 2015, ANN VASC SURG, V29, P1353, DOI 10.1016/j.avsg.2015.05.007
   Almeida CEPC, 2014, INT J SURG, V12, P1100, DOI 10.1016/j.ijsu.2014.08.397
   Perl TM, 2002, NEW ENGL J MED, V346, P1871, DOI 10.1056/NEJMoa003069
   PITT HA, 1980, ANN SURG, V192, P356, DOI 10.1097/00000658-198009000-00011
   Pleger SP, 2018, INT WOUND J, V15, P75, DOI 10.1111/iwj.12836
   Prakken Frederik J, 2011, Ned Tijdschr Geneeskd, V155, pA3269
   Puhan MA, 2014, BMJ-BRIT MED J, V349, DOI 10.1136/bmj.g5630
   Ratliff CR, 2017, J WOUND OSTOMY CONT, V44, P524, DOI 10.1097/WON.0000000000000376
   Reed James F 3rd, 2008, Int J Low Extrem Wounds, V7, P210, DOI 10.1177/1534734608324172
   Ricco JB, 2006, J VASC SURG, V44, P339, DOI 10.1016/j.jvs.2006.03.046
   ROTTER ML, 1988, J HOSP INFECT, V11, P310, DOI 10.1016/0195-6701(88)90083-7
   Sabat J, 2016, J VASC SURG, V63, p94S, DOI 10.1016/j.jvs.2016.03.099
   Sexton F, 2020, INT J SURG, V76, P94, DOI 10.1016/j.ijsu.2020.02.037
   Shi DM, 2017, J CLIN NURS, V26, P2907, DOI 10.1111/jocn.13661
   Showen A, 2017, AM SURGEON, V83, P1108
   Siracuse JJ, 2014, VASC ENDOVASC SURG, V48, P27, DOI 10.1177/1538574413508827
   Siracuse JJ, 2013, J VASC SURG, V57, P700, DOI 10.1016/j.jvs.2012.09.049
   SOTERIOU M, 1989, WORLD J SURG, V13, P798, DOI 10.1007/BF01658441
   Steely AM, 2017, ANN VASC SURG, V44, P211, DOI 10.1016/j.avsg.2017.04.020
   Stewart A, 2006, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003073.pub2
   Stewart AH, 2007, J VASC SURG, V46, P148, DOI 10.1016/j.jvs.2007.02.065
   Tanner J, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004122.pub4
   Taylor Tracy, 2005, Br J Perioper Nurs, V15, P518
   Teixeira PGR, 2015, J VASC SURG, V61, P1264, DOI 10.1016/j.jvs.2014.12.049
   Turtiainen J, 2014, SCAND J SURG, V103, P226, DOI 10.1177/1457496913514384
   Turtiainen J, 2012, WORLD J SURG, V36, P2528, DOI 10.1007/s00268-012-1655-4
   van der Slegt J, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0071566
   Vierhout BP, 2014, SURG INFECT, V15, P425, DOI 10.1089/sur.2013.191
   Vogel TR, 2010, J VASC SURG, V51, P122, DOI 10.1016/j.jvs.2009.08.006
   WALKER M, 1984, J HOSP INFECT, V5, P101, DOI 10.1016/0195-6701(84)90039-2
   Weber WP, 2008, ANN SURG, V247, P918, DOI 10.1097/SLA.0b013e31816c3fec
   Weber WP, 2017, LANCET INFECT DIS, V17, P605, DOI 10.1016/S1473-3099(17)30176-7
   Wertheim HFL, 2004, ANN INTERN MED, V140, P419, DOI 10.7326/0003-4819-140-6-200403160-00007
   Wilson S E, 2001, Surg Infect (Larchmt), V2, P171, DOI 10.1089/109629601750469492
   Wiseman JT, 2015, J VASC SURG, V62, P1023, DOI 10.1016/j.jvs.2015.04.453
   WORNING AM, 1986, J ANTIMICROB CHEMOTH, V17, P105, DOI 10.1093/jac/17.1.105
   Wübbeke LF, 2020, EUR J VASC ENDOVASC, V59, P635, DOI [10.1016/j.jvs.2020.03.007, 10.1016/j.ejvs.2020.01.010]
   Yeager R A, 1992, Ann Vasc Surg, V6, P485
   Youssef F, 2005, EUR J VASC ENDOVASC, V29, P162, DOI 10.1016/j.ejvs.2004.09.026
   Zamani N, 2018, SURG INFECT, V19, P87, DOI 10.1089/sur.2017.193
   Ziegler TR, 2016, ANN SURG, V263, P646, DOI 10.1097/SLA.0000000000001487
NR 116
TC 10
Z9 12
U1 0
U2 8
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0890-5096
EI 1615-5947
J9 ANN VASC SURG
JI Ann. Vasc. Surg.
PD JAN
PY 2022
VL 78
BP 336
EP 361
DI 10.1016/j.avsg.2021.06.045
PG 26
WC Surgery; Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery; Cardiovascular System & Cardiology
GA 5N7CY
UT WOS:000871946700040
PM 34543711
DA 2026-07-24
ER

PT J
AU Fan, ZQ
   Yu, ZH
   Zheng, JZ
   Yu, BF
   Liu, DW
AF Fan, Zhi-Qiang
   Yu, Zhi-Hao
   Zheng, Jing-Zhou
   Yu, Bao-Fu
   Liu, De-Wu
TI Tibial cortex transverse distraction in treating diabetic foot ulcers:
   what are we concerned about?
SO JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
LA English
DT Article
DE Tibial cortex transverse distraction; diabetic foot ulcers; effects;
   surgical complications; standard operative procedure; tibial fracture
ID ILIZAROV FIXATOR
AB Objective To assess the effect and complications of tibial cortex transverse distraction (TCTD) in treating diabetic foot ulcers and draw attention to the concerning issues of this procedure. Methods This case series included 30 patients with diabetic foot ulcers from four centers. The ulcers had not healed after >6 months. The patients then underwent TCTD combined with other procedures (debridement, vacuum sealing drainage, and others). All patients were followed up for >12 months postoperatively. Results Three patients underwent amputation because of aggravated infections. Tibial fractures occurred in two patients after surgery, and the fractures healed after 3 months of plaster fixation. Pin-site infections occurred in five patients, and the infected pin site healed after the patients underwent pin removal and dressing changes for 3.3 +/- 2.1 weeks. The ulcers of the other 27 patients healed by 13.5 +/- 8.2 weeks postoperatively, and the postoperative visual analog scale score was significantly lower than the preoperative score. Conclusions Although TCTD can be performed as an adjuvant treatment for diabetic foot ulcers, the effect should not be exaggerated and the complications should not be ignored. Further research is needed to propose a standard operative procedure and avoid postoperative complications such as tibial fractures.
C1 [Fan, Zhi-Qiang] Nanchang Univ, Jiangxi Prov Peoples Hosp, Dept Orthopaed Surg, 152 Ai Guo Rd, Nanchang 330006, Jiangxi, Peoples R China.
   [Fan, Zhi-Qiang; Liu, De-Wu] Nanchang Univ, Affiliated Hosp 1, Inst Burn, Nanchang, Jiangxi, Peoples R China.
   [Yu, Zhi-Hao] Yichun Peoples Hosp, Dept Orthopaed Surg, Yichun, Jiangxi, Peoples R China.
   [Zheng, Jing-Zhou] Nanchang Shuguang Hand & Foot Surg Hosp, Dept Orthopaed Surg, Nanchang, Jiangxi, Peoples R China.
   [Yu, Bao-Fu] Fudan Univ, Huashan Hosp, Jingan Branch, Dept Hand & Upper Extrem Surg, Shanghai, Peoples R China.
C3 Nanchang University; Nanchang University; Fudan University
RP Fan, ZQ (通讯作者)，Nanchang Univ, Jiangxi Prov Peoples Hosp, Dept Orthopaed Surg, 152 Ai Guo Rd, Nanchang 330006, Jiangxi, Peoples R China.
EM medical2018@sohu.com
CR Armstrong DG, 2017, NEW ENGL J MED, V376, P2367, DOI 10.1056/NEJMra1615439
   Chen Y, 2020, CLIN ORTHOP RELAT R, V478, P836, DOI 10.1097/CORR.0000000000001075
   Fu XL, 2019, DIABETES-METAB RES, V35, DOI 10.1002/dmrr.3160
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P249, DOI 10.1097/00003086-198901000-00038
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P263
   Inam M, 2015, J PAK MED ASSOC, V65, pS94
   Khan MS, 2015, J PAK MED ASSOC, V65, pS147
   Lamm BM, 2020, J FOOT ANKLE SURG, V59, P863, DOI 10.1053/j.jfas.2019.05.011
   Liu YS, 2020, BMC MUSCULOSKEL DIS, V21, DOI 10.1186/s12891-020-03335-w
   Meloni M, 2020, J CLIN MED, V9, DOI 10.3390/jcm9061780
   Richards M, 1998, CLIN ORTHOP RELAT R, pS191
NR 11
TC 13
Z9 16
U1 0
U2 6
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 0300-0605
EI 1473-2300
J9 J INT MED RES
JI J. Int. Med. Res.
PD SEP
PY 2020
VL 48
IS 9
AR 0300060520954697
DI 10.1177/0300060520954697
PG 8
WC Medicine, Research & Experimental; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Pharmacology & Pharmacy
GA NV7VC
UT WOS:000574523200001
PM 32951489
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Rencüzogullari, A
   Dalci, K
   Eray, IC
   Yalav, O
   Okoh, AK
   Akcam, T
   Ülkü, A
   Sakman, G
   Parsak, CP
AF Rencuzogullari, Ahmet
   Dalci, Kubilay
   Eray, Ismail Cem
   Yalav, Orcun
   Okoh, Alexis Kofi
   Akcam, Tolga
   Ulku, Abdullah
   Sakman, Gurhan
   Parsak, Cam P.
TI Comparison of early surgical alternatives in the management of open
   abdomen: a randomized controlled study
SO ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA &
   EMERGENCY SURGERY
LA English
DT Article
DE Abdominal compartment syndrome; Bogota bag; intraabdominal hypertension;
   vacuum assisted closure
ID ABDOMINAL COMPARTMENT SYNDROME; INTRAABDOMINAL PRESSURE; CLOSURE;
   TRAUMA; DEVICE; SEPSIS
AB BACKGROUND: Abdominal compartment syndrome (ACS) is a clinical syndrome characterized by progressive intraabdominal organ dysfunction resulting from an acute increase in intra-abdominal pressure (IAP). In the absence of prompt treatment, ACS can lead to lethal organ failure. Treatment of ACS is achieved by immediate decompression of the abdominal cavity. As to how and when decompression laparotomy should be performed depends on the clinical condition of the patients. There is limited data regarding outcomes of abdominal closure techiques. The present study aimed to investigate two different temporary closure methods, the vacuum assisted closure (VAC) and Bogota bag techniques, in 40 patients who underwent decompressive laparotomy as part of the management of ACS.
   METHODS: The study included 40 patients who developed ACS during follow-up or following trauma and abdominal surgery. As part of the treatment for ACS, these patients underwent decompressive laparotomy at the Cukurova University Medical Faculty, General Surgery Department and followed up in the Intensive Care Unit of the same hospital. VAC and Bogota bag procedures were performed as temporary closure methods for the treatment of ACS. Patients were randomly assigned to each of the two groups according to the temporary closure method performed. Clinical, laboratory, mortality and morbidity results of the patients in both groups were compared.
   RESULTS: Demographic features of the patients (age, sex, body mass index, co-morbidities) were similar between the two groups. The most common reason of ACS was gastrointestinal perforation in 12 (30%) patients. Decrease in incision width was significantly faster in the VAC group than in the Bogota group. Primary closure of fascia was considered appropriate in 16.9 days in the VAC group and 20.5 days in the Bogota bag group. The decrease in abdominal pressure was similar between the two groups on days 1, 4 and 7 but appeared to be significantly lower on day 14 in the VAC group. 12 patients (30%) died during the study. Among the deceased patients, 5 (12%) were in the VAC group, whereas, 7 (17.5%) belonged to the Bogota bag group.
   CONCLUSION: Based on these results, it is suggested that VAC has advantages when compared to the Bogota bag as a temporary closure method in the management of abdominal compartment syndrome.
C1 [Rencuzogullari, Ahmet; Dalci, Kubilay; Eray, Ismail Cem; Yalav, Orcun; Akcam, Tolga; Ulku, Abdullah; Sakman, Gurhan; Parsak, Cam P.] Cukurova Univ, Fac Med, Dept Gen Surg, Adana, Turkey.
   [Okoh, Alexis Kofi] Ankara Univ, Fac Med, Dept Gen Surg, TR-06100 Ankara, Turkey.
C3 Cukurova University; Ankara University
RP Rencüzogullari, A (通讯作者)，Balcali Hastanesi, TR-01330 Adana, Turkey.
EM rncz1980@gmail.com
RI Dalcı, Kubilay/K-1798-2018; /J-8033-2018; Akcam, Atılgan/K-2237-2018;
   Okoh, Alexis/F-7755-2015
CR [Anonymous], AKTUEL TIP DERGISI
   [Anonymous], CORE TOPICS GEN EMER
   [Anonymous], CRITICAL CARE POSTGR
   [Anonymous], CURR OPIN CRIT CARE
   [Anonymous], COMPLICATIONS SURG
   [Anonymous], EUR J TRAUMA
   Barker DE, 2000, J TRAUMA, V48, P201, DOI 10.1097/00005373-200002000-00001
   Batacchi S, 2009, CRIT CARE, V13, DOI 10.1186/cc8193
   Benninger E, 2008, J SURG RES, V144, P102, DOI 10.1016/j.jss.2007.02.021
   COLLICOTT PE, 1980, JAMA-J AM MED ASSOC, V243, P1156
   Deenichin GP, 2008, SURG TODAY, V38, P5, DOI 10.1007/s00595-007-3573-x
   Eddy V, 1997, SURG CLIN N AM, V77, P801, DOI 10.1016/S0039-6109(05)70585-5
   FANSLER RF, 1995, AM J SURG, V170, P15, DOI 10.1016/S0002-9610(99)80244-X
   Howdieshell TR, 2004, AM J SURG, V188, P301, DOI 10.1016/j.amjsurg.2004.03.007
   Hutchins RR, 2004, WORLD J SURG, V28, P137, DOI 10.1007/s00268-003-7067-8
   IBERTI TJ, 1987, CRIT CARE MED, V15, P1140, DOI 10.1097/00003246-198712000-00014
   KRON IL, 1984, ANN SURG, V199, P28, DOI 10.1097/00000658-198401000-00005
   LACEY SR, 1987, J PEDIATR SURG, V22, P1207, DOI 10.1016/S0022-3468(87)80739-X
   Long KL, 2014, AM SURGEON, V80, P567
   Losanoff JE, 2002, J AM COLL SURGEONS, V195, P105, DOI 10.1016/S1072-7515(02)01149-3
   Malbrain Manu L N G, 2004, Curr Opin Crit Care, V10, P132, DOI 10.1097/00075198-200404000-00010
   Mayberry JC, 1997, ARCH SURG-CHICAGO, V132, P957
   Meldrum DR, 1997, AM J SURG, V174, P667, DOI 10.1016/S0002-9610(97)00201-8
   MORRIS JA, 1993, ANN SURG, V217, P576, DOI 10.1097/00000658-199305010-00019
   Navsaria PH, 2003, BRIT J SURG, V90, P718, DOI 10.1002/bjs.4101
   OBEID F, 1995, ARCH SURG-CHICAGO, V130, P544
   Parsak CK, 2008, WORLD J SURG, V32, P13, DOI 10.1007/s00268-007-9286-x
   Rutherford Edmund J, 2004, Curr Probl Surg, V41, P815
   Saggi B, 1998, J TRAUMA, V45, P597, DOI 10.1097/00005373-199809000-00033
   Schecter WP, 2006, J AM COLL SURGEONS, V203, P390, DOI 10.1016/j.jamcollsurg.2006.06.001
   SCHEIN M, 1995, J AM COLL SURGEONS, V180, P745
   Stonerock CE, 2003, AM SURGEON, V69, P1030
   Townsend C.M., 2004, SABISTON TXB SURG, V17th
   Vertrees A, 2006, J AM COLL SURGEONS, V202, P762, DOI 10.1016/j.jamcollsurg.2006.02.008
NR 34
TC 7
Z9 10
U1 0
U2 1
PU TURKISH ASSOC TRAUMA EMERGENCY SURGERY
PI ISTANBUL
PA KOPRULU MEHMET PASA SOC, DENIZ ABDAL MAH, DADASOGLU AP, 25-1 SEHREMINI,
   ISTANBUL, 00000, TURKEY
SN 1306-696X
J9 ULUS TRAVMA ACIL CER
JI Ulus. Travma Acil Cerrahi Derg.
PD MAY
PY 2015
VL 21
IS 3
BP 168
EP 174
DI 10.5505/tjtes.2015.09804
PG 7
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA CI5DD
UT WOS:000354772200002
PM 26033648
OA Bronze
DA 2026-07-24
ER

PT J
AU Duzgun, S
   Ozdemir, MT
   Manti, N
   Ulgen, NK
   Akkurt, MO
AF Duzgun, Serdar
   Ozdemir, Mehmet Taner
   Manti, Nurettin
   Ulgen, Nuri Koray
   Akkurt, Mehmet Orcun
TI Optimizing Outcomes in Mangled Lower Extremity Reconstruction: Insights
   from a Retrospective Study of 93 Patients and Their Functional Scores
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE lower extremity injury; reconstruction; MESS; Gustilo-Anderson; LEFS
ID LOWER-LIMB; OPEN FRACTURES; AMPUTATION; SALVAGE; SCALE; EPIDEMIOLOGY;
   INJURIES; THERAPY; LEG
AB Background/Objectives: Over the past 25 years, reconstructive techniques and patient management advancements have significantly improved outcomes in mangled lower extremity injuries. Functional results of limb salvage have been demonstrated to surpass those of primary amputations. Developments such as local fasciocutaneous flaps, vacuum-assisted closure, and hyperbaric oxygen therapy have enhanced the reconstructive ladder. Despite progress, the utility of the Mangled Extremity Severity Score (MESS) and Gustilo-Anderson classification remains debated, particularly in their prognostic value for limb salvage decisions. In the study, we aimed to evaluate the outcomes of optimizing mangled lower extremity reconstruction in 93 patients, focusing on their functional scores retrospectively. Methods: This retrospective study analyzed 93 patients treated for mangled lower extremities between January 2015 and October 2022. Patients were assessed for age, gender, injury location, MESSs, Gustilo-Anderson classifications, surgical methods, and functional outcomes using the Lower Extremity Functional Scale (LEFS). Surgical interventions included internal and external fixation, skin grafts, local flaps, muscle flaps, and free tissue transfer. LEFS scores were categorized into disability levels for functional evaluation. Correlations were drawn between LEFS and variables such as MESS, Gustilo-Anderson types, and nerve injuries. Results: Among the 93 patients, 16 had MESSs >= 7, and 77 had MESSs < 7. Reconstruction methods included local fasciocutaneous and muscle flaps (37 patients), free tissue transfer (29 patients), and skin grafting with vacuum-assisted closure (27 patients). Smoking was associated with delayed union and increased infection rates. LEFS scores were significantly lower in patients with MESSs >= 7, Gustilo grade 3C fractures, and tibial nerve injuries. Flap failures and a higher number of surgeries (>3) also correlated with poorer functional outcomes. The average soft tissue healing time was 18 days, and bone union time was 17 weeks. Conclusions: Lower extremity reconstruction demands precise surgical planning and execution, prioritizing functional restoration. MESSs and Gustilo-Anderson classifications provide practical frameworks but have limitations in predicting long-term functionality. Factors such as joint involvement, nerve injuries, and flap selection significantly influence outcomes. Smoking and delayed healing remain critical challenges. While free flaps are essential for complex defects, more straightforward methods yield better outcomes in suitable cases. LEFS emerged as a reliable tool.
C1 [Duzgun, Serdar] Anadolu Med Ctr Hosp, Dept Plast & Reconstruct Surg, TR-41400 Kocaeli, Turkiye.
   [Ozdemir, Mehmet Taner] Anadolu Med Ctr Hosp, Dept Orthoped & Traumatol, TR-41400 Kocaeli, Turkiye.
   [Manti, Nurettin] Ankara Bilkent City Hosp, Dept Orthoped & Traumatol, TR-06800 Ankara, Turkiye.
   [Ulgen, Nuri Koray; Akkurt, Mehmet Orcun] Ankara Sincan Training & Res Hosp, Dept Orthoped & Traumatol, TR-06949 Ankara, Turkiye.
C3 Anadolu Medical Center; Anadolu Medical Center
RP Manti, N (通讯作者)，Ankara Bilkent City Hosp, Dept Orthoped & Traumatol, TR-06800 Ankara, Turkiye.; Akkurt, MO (通讯作者)，Ankara Sincan Training & Res Hosp, Dept Orthoped & Traumatol, TR-06949 Ankara, Turkiye.
EM serdarduzgun@gmail.com; taner.ozdemir@anadolusaglik.org;
   nurettinmanti@gmail.com; nurikoray@gmail.com; mehorcun@gmail.com
RI MANTI, NURETTİN/LZE-0174-2024; Ulgen, Nuri Koray/PFJ-8685-2025; akkurt,
   mehmet/GNW-5065-2022; duzgun, serdar/MIQ-6030-2025
OI MANTI, NURETTİN/0000-0002-1607-0420; Ulgen, Nuri
   Koray/0000-0003-0301-3432; 
CR Adlana NA, 2020, Systematic Reviews in Pharmacy, V11, P1661
   Águila-Ledesma IR, 2019, Acta ortop. mex, V33, P2
   Berner JE, 2023, EUR J ORTHOP SURG TR, V33, P1463, DOI 10.1007/s00590-022-03324-w
   Bosse MJ, 2002, NEW ENGL J MED, V347, P1924, DOI 10.1056/NEJMoa012604
   Cannada Lisa K, 2015, J Orthop Trauma, V29 Suppl 12, pS39, DOI [10.1097/bot.0000000000000468, 10.1097/BOT.0000000000000468]
   Cho JH, 2016, J ORTHOP SCI, V21, P63, DOI 10.1016/j.jos.2015.10.022
   Citaker S, 2016, ARCH ORTHOP TRAUM SU, V136, P389, DOI 10.1007/s00402-015-2384-6
   Court-Brown CM, 2012, INJURY, V43, P891, DOI 10.1016/j.injury.2011.12.007
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   Falola RA, 2018, J RECONSTR MICROSURG, V34, P327, DOI 10.1055/s-0037-1621736
   Fochtmann A, 2016, ORTHOP TRAUMATOL-SUR, V102, P785, DOI 10.1016/j.otsr.2016.04.004
   Franken JM, 2010, EUR J PLAST SURG, V33, P129, DOI 10.1007/s00238-010-0405-9
   Goyal S, 2017, WORLD J ORTHOP, V8, P385, DOI 10.5312/wjo.v8.i5.385
   He JQ, 2022, J PERS MED, V12, DOI 10.3390/jpm12091400
   Hoogervorst LA, 2021, BONE JOINT J, V103B, P769, DOI 10.1302/0301-620X.103B4.BJJ-2020-1647.R1
   Jenkins P.J., 2010, Surgery, V28, P489, DOI [DOI 10.1016/J.MPSUR.2010.07.006, 10.1016/J.MPSUR.2010.07.006]
   Jirangkul P, 2021, INJURY, V52, P3511, DOI 10.1016/j.injury.2021.06.033
   JOHANSEN K, 1990, J TRAUMA, V30, P568, DOI 10.1097/00005373-199005000-00007
   Ladlow P, 2016, J BONE JOINT SURG AM, V98, P1996, DOI 10.2106/JBJS.15.01210
   Larsen P, 2015, INJURY, V46, P746, DOI 10.1016/j.injury.2014.12.027
   Lin CWC, 2009, PHYS THER, V89, P580, DOI 10.2522/ptj.20080290
   Loja MN, 2017, J TRAUMA ACUTE CARE, V82, P518, DOI 10.1097/TA.0000000000001339
   Mehta SP, 2016, J ORTHOP SPORT PHYS, V46, P200, DOI [10.1016/j.physio.2015.03.1853, 10.2519/jospt.2016.6165]
   Oliveira Rafael Valadares, 2018, Rev. bras. ortop., V53, P314, DOI [10.1016/j.rbo.2017.03.017, 10.1016/j.rboe.2018.03.005, 10.1016/j.rboe.2018.03.005]
   Pan SL, 2014, INJURY, V45, P1759, DOI 10.1016/j.injury.2014.05.022
   Parrett BM, 2006, PLAST RECONSTR SURG, V117, P1315, DOI 10.1097/01.prs.0000204959.18136.36
   Patel D, 2022, CUREUS J MED SCIENCE, V14, DOI 10.7759/cureus.22357
   Ratter J, 2022, J PATIENT-REP OUTCOM, V6, DOI 10.1186/s41687-022-00417-2
   Reddy Vikram, 2008, Plast Reconstr Surg, V121, P1, DOI 10.1097/01.prs.0000305928.98611.87
   SERAFIN D, 1983, CLIN PLAST SURG, V10, P55
   Soni A, 2012, J BONE JOINT SURG BR, V94B, P698, DOI 10.1302/0301-620X.94B5.27948
   Tekin L, 2009, PROSTHET ORTHOT INT, V33, P17, DOI 10.1080/03093640802482542
   Venkatadass K, 2017, INJURY, V48, P2509, DOI 10.1016/j.injury.2017.09.010
   Webb LX, 2007, J BONE JOINT SURG AM, V89A, P923, DOI 10.2106/JBJS.F.00776
NR 34
TC 3
Z9 4
U1 0
U2 0
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD MAR
PY 2025
VL 14
IS 5
AR 1436
DI 10.3390/jcm14051436
PG 12
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 0DI1L
UT WOS:001444660200001
PM 40094922
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Polat, E
   Kutlubay, Z
   Sirekbasan, S
   Gökalp, H
   Akarirmak, Ü
AF Polat, Erdal
   Kutlubay, Zekayi
   Sirekbasan, Serhat
   Gokalp, Hilal
   Akarirmak, Ulku
TI Treatment of pressure ulcers with larvae of Lucilia sericata
SO TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION
LA English
DT Article
DE Decubitus ulcer; Lucilia sericata larvae; Maggot debridement therapy
ID MAGGOT THERAPY
AB Objectives: This study aims to investigate the use of the Lucilia sericata larvae in patients with decubitus ulcers resistant to hyperbaric oxygen treatment, vacuum-assisted closure, surgical debridement, and other conventional therapies.
   Patients and methods: A total of 36 patients (21 females, 15 males; mean age 63.7 years; range 16 to 90 years) who were admitted to our hospital for decubitus ulcers between February 2011 and July 2016 were included in our study. All patients had one or more lesions in the sacral region, trochanteric area, dorsal region, or on the heel of the foot. Nine patients had spinal cord injuries, six of them were injured during a car accident, and three of them had spinal cord injuries due to gunshot. One patient had concomitant lung cancer, one had heart failure, and two patients had a diagnosis of multiple sclerosis. Thirty three of 36 patients were admitted to the wound therapy unit within the department of emergency medicine, and three were admitted to the physical therapy and rehabilitation clinic. For each patient, Lucilia sericata maggots were applied on the lesions for 72 hours and, then, washed away. This procedure was repeated two times a week. Twenty nine patients (78.9%) had four to six sessions and seven patients (21.1%) had eight to 12 sessions.
   Results: Twenty nine lesions (78.9%) were Grade 2 and 3 and were completely healed after four to eight treatment sessions, while seven lesions (21.1%) were completely cured at the end of 10 to 14 sessions. There was complete clearance of necrotic debris at the end of two sessions within the first week for 15 lesions, whereas 10 lesions (27.8%) were cured after four sessions within two weeks, seven lesions (19.4%) within five sessions after three weeks, and four lesions (11.1%) were treated at the end of seven sessions for four weeks. All the necrotic crusts over the surface of the ulcers were cleaned and bad odor of the lesions disappeared.
   Conclusion: Lucilia sericata larvae debridement is a rapid and effective treatment option for the management of chronic decubitus ulcers which are resistant to conventional therapies and other treatment modalities such as hyperbaric oxygen, vacuum-assisted closure, and surgical debridement.
C1 [Polat, Erdal; Sirekbasan, Serhat] Istanbul Univ, Cerrahpasa Med Fac, Dept Med Microbiol, Istanbul, Turkey.
   [Kutlubay, Zekayi] Istanbul Univ, Cerrahpasa Med Fac, Dept Dermatol, Istanbul, Turkey.
   [Gokalp, Hilal; Akarirmak, Ulku] Koc Univ, Med Fac, Dept Dermatol, Istanbul, Turkey.
C3 Istanbul University - Cerrahpasa; Istanbul University; Istanbul
   University; Istanbul University - Cerrahpasa; Koc University
RP Polat, E (通讯作者)，Istanbul Univ, Cerrahpasa Tip Fak, Tibbi Mikrobiyol Anabilim Dali, TR-34098 Istanbul, Turkey.
EM erdalp@istanbul.edu.tr
RI Kutlubay, Zekayi/A-6393-2018; Sirekbasan, Serhat/Q-1093-2018; POLAT,
   Erdal/D-7602-2019; AKARIRMAK, ZEYNEP ÜLKÜ/AAA-3923-2020
OI Sirekbasan, Serhat/0000-0001-7967-3539; POLAT,
   Erdal/0000-0002-3944-6443; AKARIRMAK, ZEYNEP ÜLKÜ/0000-0002-3288-3368
CR Aktas S, 2010, GUNCEL YONLERIYLE KR, P194
   Aktas S, 2008, YARA BAKIMI TEDAVISI, P199
   Amlung S R, 2001, Adv Skin Wound Care, V14, P297, DOI 10.1097/00129334-200111000-00012
   Bennett G, 2004, AGE AGEING, V33, P230, DOI 10.1093/ageing/afh086
   Bolaban D, 2009, THESIS
   Bonn D, 2000, LANCET, V356, P1174, DOI 10.1016/S0140-6736(05)72870-1
   Brin Y S, 2007, J Wound Care, V16, P111
   Coskunpinar E, 2015, CELL MOL BIOL, V61, P89
   Erdogan B, 2010, GUNCEL YONLERIYLE KR, P143
   Huberman L, 2007, J Wound Care, V16, P123
   Mumcuoglu KY, 1998, DIABETES CARE, V21, P2030, DOI 10.2337/diacare.21.11.2030
   Mumcuoglu KY, 2001, J MED ENTOMOL, V38, P161, DOI 10.1603/0022-2585-38.2.161
   Polat E, 2010, ISTANBUL TIP FAKULTE, P181
   Polat E., 2010, TURK AILE HEK DERG, V14, P188
   Polat E, 2009, TURKIYE PARAZITOLOJI, P83
   Polat E, 2007, K PROGR BILD KIT K 2, P57
   Polat E, 2014, GENE, V550, P223, DOI 10.1016/j.gene.2014.08.033
   Prete PE, 1997, LIFE SCI, V60, P505, DOI 10.1016/S0024-3205(96)00688-1
   Sherman RA, 1997, PLAST RECONSTR SURG, V100, P451, DOI 10.1097/00006534-199708000-00029
   Sherman RA, 2002, WOUND REPAIR REGEN, V10, P208, DOI 10.1046/j.1524-475X.2002.10403.x
   Thomas S., 1998, J WOUND CARE, V7, P521
   Yucel A., 2008, Yara Bakimi ve Tedavisi, P37
NR 22
TC 9
Z9 11
U1 2
U2 12
PU BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK
PI ATASEHIR
PA ORNEK MH DR SUPHI EZGI SK SARAY APT NO 11 D 6, ATASEHIR, ISTANBUL 34704,
   TURKEY
SN 2587-0823
J9 TURK J PH MED REHAB
JI Turk. J. Phys. Med. Rehabil.
PY 2017
VL 63
IS 4
BP 307
EP 312
DI 10.5606/tftrd.2017.851
PG 6
WC Rehabilitation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Rehabilitation
GA FT0CN
UT WOS:000422788100004
PM 31453472
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Ritz, LA
   Hajji, MS
   Schwerd, T
   Koletzko, S
   von Schweinitz, D
   Lurz, E
   Hubertus, J
AF Ritz, Laura Antonia
   Hajji, Mohammad Samer
   Schwerd, Tobias
   Koletzko, Sibylle
   von Schweinitz, Dietrich
   Lurz, Eberhard
   Hubertus, Jochen
TI Esophageal Perforation and EVAC in Pediatric Patients: A Case Series of
   Four Children
SO FRONTIERS IN PEDIATRICS
LA English
DT Article
DE esophageal perforation; VAC; vacuum therapy; children; pediatric
   patients
ID VACUUM-ASSISTED CLOSURE; MANAGEMENT; THERAPY; DEFECTS; LEAKAGE; DEVICE;
   SYSTEM; STENT
AB Introduction: In pediatric patients, esophageal perforation (EP) is rare but associated with significant morbidity and mortality rates of up to 20-30%. In addition to standard treatment options, endoscopic esophageal vacuum-assisted closure (EVAC) therapy has shown promising results, especially in adult patients. Thus far, the only data on technical success and effectiveness of EVAC in pediatric patients were published in 2018 by Manfredi et al. at Boston Children's Hospital. The sparse data on EVAC in children indicates that this promising technique has been barely utilized in pediatric patients. More data are needed to evaluate efficacy and outcomes of this technique in pediatric patients.
   Method: We reviewed five cases of therapy using EVAC, ArgyleTM Replogle Suction Catheter (RSC), or both on pediatric patients with EP in our institution between October 2018 and April 2020.
   Results: Five patients with EP (median 3.4 years; 2 males) were treated with EVAC, RSC, or a combination. Complete closure of EP was not achieved after EVAC alone, though patients' health stabilized and inflammation and size of EP decreased after EVAC. Four patients then were treated with RSC until the EP healed. One patient needed surgery as the recurrent fistula did not heal sufficiently after 3 weeks of EVAC therapy. Two patients developed stenosis and were successfully treated with dilatations. One patient treated with RSC alone showed persistent EP after 5 weeks.
   Conclusion: EVAC in pediatric patients is technically feasible and a promising method to treat EP, regardless of the underlying cause. EVAC therapy can be terminated as soon as local inflammation and C-reactive protein levels decrease, even if the mucosa is not healed completely at that time. A promising subsequent treatment is RSC. An earlier switch to RSC can substantially reduce the need of anesthesia during subsequent treatments. Our findings indicate that EVAC is more effective than RSC alone. In some cases, EVAC can be used to improve the tissues condition in preparation for a re-do surgery. At 1 year after therapy, all but one patient demonstrated sufficient weight gain. Further prospective studies with a larger cohort are required to confirm our observations from this small case series.
C1 [Ritz, Laura Antonia; von Schweinitz, Dietrich; Hubertus, Jochen] Ludwig Maximilian Univ Munich, Dept Pediat Surg, Dr von Hauner Childrens Hosp, Munich, Germany.
   [Hajji, Mohammad Samer; Schwerd, Tobias; Koletzko, Sibylle; Lurz, Eberhard] Ludwig Maximilian Univ Munich, Dr von Hauner Childrens Hosp, Dept Pediat Gastroenterol, Munich, Germany.
C3 University of Munich; University of Munich
RP Hubertus, J (通讯作者)，Ludwig Maximilian Univ Munich, Dept Pediat Surg, Dr von Hauner Childrens Hosp, Munich, Germany.
EM jochen.hubertus@med.uni-muenchen.de
RI Koletzko, Sibylle/KFB-8405-2024; Hubertus, Jochen/AAW-7790-2021
OI Lurz, Eberhard/0000-0002-7479-7388; Hubertus, Jochen/0000-0003-3206-6170
CR ATTAR S, 1990, ANN THORAC SURG, V50, P45, DOI 10.1016/0003-4975(90)90082-H
   Bludau M, 2014, SURG ENDOSC, V28, P896, DOI 10.1007/s00464-013-3244-5
   Bludau M, 2018, SURG ENDOSC, V32, P1906, DOI 10.1007/s00464-017-5883-4
   Braakenburg A, 2006, PLAST RECONSTR SURG, V118, P390, DOI 10.1097/01.prs.0000227675.63744.af
   Bütter A, 2006, J PEDIATR SURG, V41, P940, DOI 10.1016/j.jpedsurg.2006.01.061
   Costa J, 2018, ANN THORAC SURG, V106, pE107, DOI 10.1016/j.athoracsur.2018.03.025
   Dasari BVM, 2014, ANN SURG, V259, P852, DOI 10.1097/SLA.0000000000000564
   Fernandez FF, 1999, SURG ENDOSC-ULTRAS, V13, P962, DOI 10.1007/s004649901147
   Fraga JC, 2018, J THORAC CARDIOV SUR, V156, pE193, DOI 10.1016/j.jtcvs.2018.04.061
   Garey CL, 2010, J SURG RES, V164, P13, DOI 10.1016/j.jss.2010.05.049
   GOLDSTEIN LA, 1982, AM J SURG, V143, P495, DOI 10.1016/0002-9610(82)90202-1
   Hwang JJ, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000003416
   Jeon JH, 2020, WORLD J SURG, V44, P179, DOI 10.1007/s00268-019-05228-z
   Kaman L, 2010, GASTROENTEROL RES, V3, P235, DOI 10.4021/gr263w
   Kuehn F, 2017, SURG ENDOSC, V31, P3449, DOI 10.1007/s00464-016-5404-x
   Kuehn F, 2016, J GASTROINTEST SURG, V20, P237, DOI 10.1007/s11605-015-3044-4
   Loske G, 2011, ENDOSCOPY, V43, P540, DOI 10.1055/s-0030-1256345
   Loske G, 2015, ENDOSC INT OPEN, V3, pE547, DOI 10.1055/s-0034-1392566
   Manfredi MA, 2018, J PEDIATR GASTR NUTR, V67, P706, DOI 10.1097/MPG.0000000000002073
   McCann F, 2015, DIS ESOPHAGUS, V28, P211, DOI 10.1111/dote.12176
   MedlinePlus, 2021, NORM GROWTH DEV
   Mennigen R, 2015, J GASTROINTEST SURG, V19, P1229, DOI 10.1007/s11605-015-2847-7
   Michaud L, 2013, ORPHANET J RARE DIS, V8, DOI 10.1186/1750-1172-8-186
   Onwuka EA, 2016, J SURG RES, V205, P102, DOI 10.1016/j.jss.2016.06.027
   Raum M, 2018, J PEDIAT SURG CASE R, V33, P55, DOI 10.1016/j.epsc.2018.04.001
   Rentea RM, 2017, SEMIN PEDIATR SURG, V26, P87, DOI 10.1053/j.sempedsurg.2017.02.005
   RICHARDSON JD, 1994, ARCH SURG-CHICAGO, V129, P541
   Saziye K, 2015, VASCULAR, V23, P144, DOI 10.1177/1708538114537488
   Schintler MV, 2008, EUR SURG, V40, P11, DOI 10.1007/s10353-008-0381-5
   Schintler MV, 2012, DIABETES-METAB RES, V28, P72, DOI 10.1002/dmrr.2243
   Schorsch T, 2013, SURG ENDOSC, V27, P2040, DOI 10.1007/s00464-012-2707-4
   Smallwood NR, 2016, SURG ENDOSC, V30, P2473, DOI 10.1007/s00464-015-4501-6
   VANDERZEE DC, 1988, J THORAC CARDIOV SUR, V95, P692
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Vogel SB, 2005, ANN SURG, V241, P1016, DOI 10.1097/01.sla.0000164183.91898.74
   Weidenhagen R, 2004, SHOCK, V21, P152, DOI 10.1097/00024382-200403001-00608
NR 36
TC 11
Z9 12
U1 0
U2 1
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 2296-2360
J9 FRONT PEDIATR
JI Front. Pediatr.
PD AUG 6
PY 2021
VL 9
AR 727472
DI 10.3389/fped.2021.727472
PG 6
WC Pediatrics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pediatrics
GA UH8FO
UT WOS:000690159600001
PM 34458215
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Maegele, M
   Gregor, S
   Yuecel, N
   Simanski, C
   Paffrath, T
   Rixen, D
   Heiss, MM
   Rudroff, C
   Saad, S
   Perbix, W
   Wappler, F
   Harzheim, A
   Schwarz, R
   Bouillon, B
AF Maegele, Marc
   Gregor, Sven
   Yuecel, Nedim
   Simanski, Christian
   Paffrath, Thomas
   Rixen, Dieter
   Heiss, Markus M.
   Rudroff, Claudia
   Saad, Stefan
   Perbix, Walter
   Wappler, Frank
   Harzheim, Andreas
   Schwarz, Rosemarie
   Bouillon, Bertil
TI One year ago not business as usual: Wound management, infection and
   psychoemotional control during tertiary medical care following the 2004
   Tsunami disaster in southeast Asia
SO CRITICAL CARE
LA English
DT Article
ID VACUUM-SEALING TECHNIQUE; AEROMONAS-HYDROPHILA; SOFT-TISSUE; CUTANEOUS
   MELIOIDOSIS; ASSISTED CLOSURE; SURVIVORS; PNEUMONIA; THAILAND;
   PSEUDOMALLEI; TRIAL
AB Introduction Following the 2004 tsunami disaster in southeast Asia severely injured tourists were repatriated via airlift to Germany. One cohort was triaged to the Cologne-Merheim Medical Center ( Germany) for further medical care. We report on the tertiary medical care provided to this cohort of patients.
   Methods This study is an observational report on complex wound management, infection and psychoemotional control associated with the 2004 Tsunami disaster. The setting was an adult intensive care unit (ICU) of a level I trauma center and subjects included severely injured tsunami victims repatriated from the disaster area ( 19 to 68 years old; 10 females and 7 males with unknown co-morbidities).
   Results Multiple large flap lacerations ( 2 x 3 to 60 x 60 cm) at various body sites were characteristic. Lower extremities were mostly affected (88%), followed by upper extremities (29%), and head (18%). Two-thirds of patients presented with combined injuries to the thorax or fractures. Near-drowning involved the aspiration of immersion fluids, marine and soil debris into the respiratory tract and all patients displayed signs of pneumonitis and pneumonia upon arrival. Three patients presented with severe sinusitis. Microbiology identified a variety of common but also uncommon isolates that were often multiresistant. Wound management included aggressive debridement together with vacuum-assisted closure in the interim between initial wound surgery and secondary closure. All patients received empiric anti-infective therapy using quinolones and clindamycin, later adapted to incoming results from microbiology and resistance patterns. This approach was effective in all but one patient who died due to severe fungal sepsis. All patients displayed severe signs of post-traumatic stress response.
   Conclusion Individuals evacuated to our facility sustained traumatic injuries to head, chest, and limbs that were often contaminated with highly resistant bacteria. Transferred patients from disaster areas should be isolated until their microbial flora is identified as they may introduce new pathogens into an ICU. Successful wound management, including aggressive debridement combined with vacuum-assisted closure was effective. Initial anti-infective therapy using quinolones combined with clindamycin was a good first-line choice. Psychoemotional intervention alleviated severe post-traumatic stress response. For optimum treatment and care a multidisciplinary approach is mandatory.
C1 Univ Witten Herdecke, CMMC, Dept Traumatol & Orthoped Surg, Intens Care Unit, D-51109 Cologne, Germany.
   Univ Witten Herdecke, CMMC, Dept Visceral Surg, D-51109 Cologne, Germany.
   Univ Witten Herdecke, CMMC, Dept Plast & Reconstruct Surg, D-51109 Cologne, Germany.
   Univ Witten Herdecke, CMMC, Dept Anaesthesiol, D-51109 Cologne, Germany.
   Univ Witten Herdecke, CMMC, Dept Radiol, D-51109 Cologne, Germany.
   Univ Witten Herdecke, CMMC, Dept Microbiol, D-51109 Cologne, Germany.
C3 Witten Herdecke University; University of Cologne; Witten Herdecke
   University; University of Cologne; Witten Herdecke University;
   University of Cologne; University of Cologne; Witten Herdecke
   University; University of Cologne; Witten Herdecke University;
   University of Cologne; Witten Herdecke University
RP Maegele, M (通讯作者)，Univ Witten Herdecke, CMMC, Dept Traumatol & Orthoped Surg, Intens Care Unit, Ostmerheimerstr, D-51109 Cologne, Germany.
EM Marc.Maegele@t-online.de
RI Rudroff, Claudia Lieselotte/KSM-9547-2024
OI Rudroff, Claudia Lieselotte/0000-0003-3347-0108
CR Allworth AM, 2005, MED J AUSTRALIA, V182, P364, DOI 10.5694/j.1326-5377.2005.tb06738.x
   Andresen D, 2005, LANCET, V365, P876, DOI 10.1016/S0140-6736(05)71046-1
   [Anonymous], 2005, MMWR MORB MORTAL WKL, V54, P61
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   BODMANN KF, 2001, CHEMOTHERAPIE J, V10, P43
   BONE RC, 1992, CHEST, V101, P1644, DOI 10.1378/chest.101.6.1644
   BUHRING P, 2005, DT ARZTEBLATT, V102, pB87
   Chierakul W, 2005, CLIN INFECT DIS, V41, P982, DOI 10.1086/432942
   Dries D, 2005, CRIT CARE MED, V33, P1178, DOI 10.1097/01.CCM.0000163220.55649.F0
   Easton A, 1999, BMJ-BRIT MED J, V319, P212
   Ender Peter T., 1996, Journal of Emergency Medicine, V14, P737, DOI 10.1016/S0736-4679(96)00183-7
   Ender PT, 1997, CLIN INFECT DIS, V25, P896, DOI 10.1086/515532
   Fleischmann W, 1997, UNFALLCHIRURG, V100, P301, DOI 10.1007/s001130050123
   GABEL A, 2005, DT ARZTEBLATT, V102, pB82
   Garzoni C, 2005, EMERG INFECT DIS, V11, P1591, DOI 10.3201/eid1110.050715
   GENONI L, 1982, SCHWEIZ MED WSCHR, V112, P867
   GOLD WL, 1993, CLIN INFECT DIS, V16, P69, DOI 10.1093/clinids/16.1.69
   Hiransuthikul N, 2005, CLIN INFECT DIS, V41, pE93, DOI 10.1086/497372
   Holian AC, 1998, MED J AUSTRALIA, V169, P606, DOI 10.5694/j.1326-5377.1998.tb123433.x
   Holmberg S D, 1988, Infect Dis Clin North Am, V2, P655
   Joseph E, 2000, WOUNDS, V12, P60
   Jukema G N, 1997, Langenbecks Arch Chir Suppl Kongressbd, V114, P581
   Kongsaengdao S, 2005, NEW ENGL J MED, V352, P2654, DOI 10.1056/NEJM200506233522523
   LEE N, 1985, J CLIN MICROBIOL, V22, P352, DOI 10.1128/JCM.22.3.352-354.1985
   Leppäniemi A, 2005, SCAND J SURG, V94, P5, DOI 10.1177/145749690509400103
   Lim PL, 2005, ANN ACAD MED SINGAP, V34, P582
   Limchawalit K, 2005, NEW ENGL J MED, V352, pE23, DOI 10.1056/NEJMicm050461
   Maccanti O, 2004, J CHEMOTHERAPY, V16, P404, DOI 10.1179/joc.2004.16.4.404
   Maegele M, 2005, CRIT CARE MED, V33, P1136, DOI 10.1097/01.CCM.0000163269.42524.50
   Maluping RP, 2004, MICROBIOLOGICA, V27, P381
   Masur H, 2005, CRIT CARE MED, V33, P1179, DOI 10.1097/01.CCM.0000163271.78189.0F
   Mendez-Eastman S, 1998, Plast Surg Nurs, V18, P27
   Miller G, 2005, SCIENCE, V309, P1030, DOI 10.1126/science.309.5737.1030
   Miyake M, 2000, INTERNAL MED, V39, P1128, DOI 10.2169/internalmedicine.39.1128
   Mullner T, 1997, BRIT J PLAST SURG, V50, P194, DOI 10.1016/S0007-1226(97)91369-2
   NIEMINEN T, 2005, EUROSURVEILLANCE WEE, V10
   OUTIN HD, 1984, ANN MED INTERNE, V135, P287
   PATINO JF, 1991, WORLD J SURG, V15, P240, DOI 10.1007/BF01659059
   REINES HD, 1981, CHEST, V80, P264, DOI 10.1378/chest.80.3.264
   ROSENTHAL SL, 1975, AM J CLIN PATHOL, V64, P382
   Seguin P, 1999, EUR J CLIN MICROBIOL, V18, P737, DOI 10.1007/s100960050389
   SEMEL JD, 1990, J TRAUMA, V30, P324, DOI 10.1097/00005373-199003000-00011
   SIMS JK, 1983, ANN EMERG MED, V12, P212, DOI 10.1016/S0196-0644(83)80597-6
   Svensson E, 2006, SCAND J INFECT DIS, V38, P71, DOI 10.1080/00365540500264738
   Taylor RP, 1998, MED J AUSTRALIA, V169, P602, DOI 10.5694/j.1326-5377.1998.tb123432.x
   Wang YS, 2003, EMERG INFECT DIS, V9, P1484, DOI 10.3201/eid0911.030370
   Wattanawaitunechai C, 2005, NEW ENGL J MED, V352, P962, DOI 10.1056/NEJMp058040
   ZYLKAMENHORN V, 2005, DT ARZTEBLATT, V102, pB85
NR 48
TC 37
Z9 37
U1 0
U2 7
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1466-609X
EI 1364-8535
J9 CRIT CARE
JI Crit. Care
PY 2006
VL 10
IS 2
AR R50
DI 10.1186/cc4868
PG 9
WC Critical Care Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA 083DP
UT WOS:000240436400011
PM 16584527
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Wei, DQ
   Xu, YB
   Xiang, FF
   Ye, JW
AF Wei, Daiqing
   Xu, Yangbo
   Xiang, Feifan
   Ye, Junwu
TI Secondary below-knee amputation following open reduction and internal
   fixation of a closed pilon fracture A case report and algorithm for
   management
SO MEDICINE
LA English
DT Article
DE amputation; case report; closed fracture; ischemia; pilon fracture
ID ANKLE FRACTURE
AB Rationale: Despite significant advances in surgical techniques and implants, the clinical outcome of high-energy pilon fractures remains unsatisfactory, which continues to represent numerous challenges for orthopedic trauma surgeons. Patient concerns: A 62-year-old man injured his right ankle after falling from a 3 m high place. There were no open wounds or other complications. Diagnoses: According to the X-ray and CT scans, the patient was diagnosed with pilon fracture (type AO-43-C2) and lateral malleolus fracture of the right limb. Interventions: The patient was initially treated with calcaneal traction upon admission to a primary hospital. Five days after the injury, the patient underwent open reduction and internal fixation (ORIF) of the fracture and vacuum sealing drainage (VSD) for wound closure. Outcomes: The patient presented to our hospital on the 9th day after the first ORIF operation because of critical ischemia of the affected foot and distal lower leg. Blood circulation did not improve after a series of salvage treatments, and below-knee amputation was ultimately performed. Lessons: This is a rare case of complete ischemic necrosis following ORIF surgery of a closed pilon fracture due to iatrogenic damage. Standardized treatment that strictly follows the guidelines, instructions, or expert consensus should be promoted in this kind of complicated pilon fracture.
C1 [Wei, Daiqing; Xu, Yangbo; Xiang, Feifan; Ye, Junwu] Southwest Med Univ, Dept Orthopaed, Affiliated Hosp, 25 Tai Ping St, Luzhou 646000, Sichuan, Peoples R China.
   [Wei, Daiqing; Xu, Yangbo; Xiang, Feifan; Ye, Junwu] Sichuan Prov Lab Orthopaed Engn, Luzhou, Sichuan, Peoples R China.
C3 Southwest Medical University
RP Ye, JW (通讯作者)，Southwest Med Univ, Dept Orthopaed, Affiliated Hosp, 25 Tai Ping St, Luzhou 646000, Sichuan, Peoples R China.
EM 1456865780@qq.com
FU Research Project of the Education Department of Sichuan Province
   [18ZA0533]
FX This work was supported by the Research Project of the Education
   Department of Sichuan Province (grant number: 18ZA0533).
CR Bear J, 2018, CURR REV MUSCULOSKE, V11, P537, DOI 10.1007/s12178-018-9519-7
   Bellezza PA, 2017, J FOOT ANKLE SURG, V56, P92, DOI 10.1053/j.jfas.2016.08.006
   Causey MW, 2010, J VASC SURG, V52, P734, DOI 10.1016/j.jvs.2010.03.065
   Evangelista Perry J, 2013, Am J Orthop (Belle Mead NJ), V42, P569
   Jacob N, 2015, STRATEG TRAUMA LIMB, V10, P137, DOI 10.1007/s11751-015-0231-5
   Kottmeier SA, 2018, J AM ACAD ORTHOP SUR, V26, P640, DOI 10.5435/JAAOS-D-17-00160
   Mauffrey C, 2011, ACTA ORTHOP BELG, V77, P432
   Saad BN, 2019, ORTHOP RES REV, V11, P149, DOI 10.2147/ORR.S170956
   Sandelin H, 2017, ACTA ORTHOP, V88, P358, DOI 10.1080/17453674.2016.1262679
   Tomás-Hernández J, 2016, EFORT OPEN REV, V1, P354, DOI 10.1302/2058-5241.1.000016
   Wynes J, 2014, J FOOT ANKLE SURG, V53, P353, DOI 10.1053/j.jfas.2014.01.001
   Zelle BA, 2019, INT ORTHOP, V43, P1939, DOI 10.1007/s00264-019-04344-8
NR 12
TC 2
Z9 2
U1 0
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD FEB 19
PY 2021
VL 100
IS 7
AR e24791
DI 10.1097/MD.0000000000024791
PG 6
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA SO4ZR
UT WOS:000658982900075
PM 33607836
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Wang, J
AF Wang, Jun
TI Reconstructing abdominal wall defects with a free composite tissue flap:
   A case report
SO WORLD JOURNAL OF CLINICAL CASES
LA English
DT Article
DE Abdominal wall defect; Anterolateral thigh flap; Repair; Tensor fascia
   lata; Case report
AB BACKGROUND
   Reconstructive repair of huge full-thickness abdominal wall defects following debridement for abdominal electric burns remains a clinically challenging task. An ideal abdominal wall repair means a re-closure of the defected abdominal wall with pedicled neurovascular myofascial flaps, restoration of the abdominal wall integrity, and maintenance of the abdominal wall muscle tension to prevent the occurrence of abdominal wall hernia. When treating huge full-thickness defects, composite autologous tissue flaps are a good option for the repair.
   CASE SUMMARY
   This study reported the case of a 43-year-old male patient suffering from full-thickness abdominal wall defects complicated with necrosis of multiple bowel segments and duodenal leak following high-voltage burns involving the left upper limb and abdomen. After debridement for abdominal electric burns and end-to-end anastomosis for the necrotic bowels, reconstruction with acellular dermal matrix grafting and vacuum sealing drainage were performed for temporary abdominal closure. The remaining 18 cm x 15 cm full-thickness abdominal wall defect was repaired using a combined anterolateral thigh and tensor fascia lata free flap. The proposed method achieved the functional reconstruction of the abdominal wall.
   CONCLUSION
   This approach restored the abdominal wall integrity, maintained certain muscle tension, avoided abdominal hernia, reached satisfactory aesthetic effect, and resulted in no complications in the grafting regions.
C1 [Wang, Jun] Hainan Med Univ, Hainan Affiliated Hosp, Hainan Gen Hosp, Dept Burn & Skin Repair Surg, 19 Xiuhua Rd, Haikou 570311, Hainan, Peoples R China.
C3 Hainan Medical University
RP Wang, J (通讯作者)，Hainan Med Univ, Hainan Affiliated Hosp, Hainan Gen Hosp, Dept Burn & Skin Repair Surg, 19 Xiuhua Rd, Haikou 570311, Hainan, Peoples R China.
EM wanggg23@hainmc.edu.cn
CR Caliceti Umberto, 2019, JPRAS Open, V22, P55, DOI [10.1016/j.jpra.2019.09.003, 10.1016/j.jpra.2019.09.003]
   Chou PY, 2019, J PLAST RECONSTR AES, V72, P1900, DOI 10.1016/j.bjps.2019.07.024
   Justo I, 2019, CIR ESPAN, V97, P247, DOI 10.1016/j.ciresp.2019.03.002
   Kadoch V, 2010, J VISC SURG, V147, pE45, DOI 10.1016/j.jviscsurg.2010.05.005
   Kagaya Y, 2020, J PLAST RECONSTR AES, V73, P638, DOI 10.1016/j.bjps.2019.11.017
   Kagaya Y, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001819
   Karhof S, 2019, INJURY, V50, P1516, DOI 10.1016/j.injury.2019.06.028
   Maloney SR, 2019, AM J SURG, V218, P1096, DOI 10.1016/j.amjsurg.2019.10.019
   Shih PK, 2019, HERNIA, V23, P749, DOI 10.1007/s10029-018-1859-0
NR 9
TC 2
Z9 4
U1 0
U2 6
PU BAISHIDENG PUBLISHING GROUP INC
PI PLEASANTON
PA 7041 Koll Center Parkway, Suite 160, PLEASANTON, CA, UNITED STATES
SN 2307-8960
J9 WORLD J CLIN CASES
JI World J. Clin. Cases
PD MAR 6
PY 2021
VL 9
IS 7
BP 1734
EP 1740
DI 10.12998/wjcc.v9.i7.1734
PG 7
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA QX0CK
UT WOS:000629016900026
PM 33728319
OA Green Accepted, gold
DA 2026-07-24
ER

PT J
AU Ciuntu, BM
   Tanevski, A
   Buescu, DO
   Lutenco, V
   Mihailov, R
   Ciuntu, MS
   Zuzu, MM
   Vintila, D
   Zabara, M
   Trofin, A
   Cadar, R
   Nastase, A
   Ursulescu, CL
   Lupascu, CD
AF Ciuntu, Bogdan Mihnea
   Tanevski, Adelina
   Buescu, David Ovidiu
   Lutenco, Valerii
   Mihailov, Raul
   Ciuntu, Madalina Stefana
   Zuzu, Mihai Marius
   Vintila, Dan
   Zabara, Mihai
   Trofin, Ana
   Cadar, Ramona
   Nastase, Alexandru
   Ursulescu, Corina Lupascu
   Lupascu, Cristian Dumitru
TI Endoscopic Vacuum-Assisted Closure (E-VAC) in Septic Shock from
   Perforated Duodenal Ulcers with Abscess Formations
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Article
DE E-VAC; negative pressure therapy; perforated duodenal ulcer; abscess
ID THERAPY; LEAK
AB This case report underscores the importance of utilizing E-VAC (endoscopic vacuum-assisted closure) in the treatment of a perforated duodenal ulcer complicated by the formation of a subphrenic abscess and septic shock. It showcases how E-VAC can effectively mitigate the risk of further complications, such as leakage, bleeding, or rupture, which are more commonly associated with traditional methods like stents, clips, or sutures. As a result, there is a significant reduction in mortality rates. A perforated duodenal ulcer accompanied by abscess formation represents a critical medical condition that demands prompt surgical intervention. The choice of the method for abscess drainage and perforation closure plays a pivotal role in determining the patient's chances of survival. Notably, in patients with a high ASA (American Association of Anesthesiologists) score of IV-V, the mortality rate following conventional surgical intervention is considerably elevated. The management of perforated duodenal ulcers has evolved from open abdominal surgical procedures, which were associated with high mortality rates and risk of suture repair leakage, to minimally invasive techniques like laparoscopy and ingestible robots. Previously, complications arising from peptic ulcers, such as perforations, leaks, and fistulas, were primarily addressed through surgical and conservative treatments. However, over the past two decades, the medical community has shifted towards employing endoscopic closure techniques, including stents, clips, and E-VAC. E-VAC, in particular, has shown promising outcomes by promoting rapid and consistent healing. This case report presents the clinical scenario of a patient diagnosed with septic shock due to a perforated duodenal ulcer with abscess formation. Following an exploratory laparotomy that confirmed the presence of a subphrenic abscess, three drainage tubes were utilized to evacuate it. Subsequently, E-VAC therapy was initiated, with the kit being replaced three times during the recovery period. The patient exhibited favorable progress, including weight gain, and was ultimately discharged as fully recovered. In the treatment of patients with duodenal perforated ulcers and associated abscess formation, the successful and comprehensive drainage of the abscess, coupled with the closure of the perforation, emerges as a pivotal factor influencing the patient's healing process. The positive outcomes observed in these patients underscore the efficacy of employing a negative pressure E-VAC kit, resulting in thorough drainage, rapid patient recovery, and low mortality rates.
C1 [Ciuntu, Bogdan Mihnea; Tanevski, Adelina; Buescu, David Ovidiu; Zuzu, Mihai Marius; Vintila, Dan; Zabara, Mihai; Trofin, Ana; Cadar, Ramona; Nastase, Alexandru; Lupascu, Cristian Dumitru] Grigore T Popa Univ Med & Pharm, Fac Med, Dept Gen Surg, 16 Univ St, Iasi 700115, Romania.
   [Ciuntu, Bogdan Mihnea; Tanevski, Adelina; Buescu, David Ovidiu; Zuzu, Mihai Marius; Vintila, Dan; Zabara, Mihai; Trofin, Ana; Cadar, Ramona; Nastase, Alexandru; Lupascu, Cristian Dumitru] St Spiridon Cty Emergency Clin Hosp, Gen Surg Clin, 1 Independence Blvd, Iasi 700111, Romania.
   [Lutenco, Valerii; Mihailov, Raul] Dunarea de Jos Univ Med & Pharm, Fac Med, Dept Gen Surg, Galati 800010, Romania.
   [Lutenco, Valerii; Mihailov, Raul] St Apostol Andrei Cty Emergency Clin Hosp, Gen Surg Clin, Str Brailei 177, Galati 800578, Romania.
   [Ciuntu, Madalina Stefana] Grigore T Popa Univ Med & Pharm, Fac Med, 16 Univ St, Iasi 700115, Romania.
   [Ursulescu, Corina Lupascu] Grigore T Popa Univ Med & Pharm, Fac Med, Dept Radiol, 16 Univ St, Iasi 700115, Romania.
C3 Grigore T Popa University of Medicine & Pharmacy; Dunarea De Jos
   University Galati; Grigore T Popa University of Medicine & Pharmacy;
   Grigore T Popa University of Medicine & Pharmacy
RP Ciuntu, BM; Tanevski, A (通讯作者)，Grigore T Popa Univ Med & Pharm, Fac Med, Dept Gen Surg, 16 Univ St, Iasi 700115, Romania.; Ciuntu, BM; Tanevski, A (通讯作者)，St Spiridon Cty Emergency Clin Hosp, Gen Surg Clin, 1 Independence Blvd, Iasi 700111, Romania.
EM bogdan-mihnea.ciuntu@ummfiasi.ro; papancea.adelina@umfiasi.ro;
   buescu_david-ovidiu@d.umfiasi.ro; vl187@student.ugal.ro;
   raul.mihailov@ugal.ro; mg-eng-24128@students.umfiasi.ro;
   zuzumihai@gmail.com; danersilia@yahoo.com; mihai.zabara@umfiasi.ro;
   ana-maria.trofin@umfiasi.ro; ramona-petronela.cadar@umfiasi.ro;
   nastase_grigorie-alexandru@d.umfiasi.ro; corina.ursulescu@umfiasi.ro;
   cristian.lupascu@umfiasi.ro
RI Lutenco, Valerii/KFQ-3946-2024; Nastase, Alexandru/NFS-1873-2025;
   Tanevski, Adelina/LUZ-8095-2024; Trofin, Ana/A-2361-2015; Ciuntu,
   Bogdan/MTF-9477-2025; Raul, Mihailov/IQU-7822-2023
OI Lutenco, Valerii/0009-0001-6620-7851; Lupascu-Ursulescu,
   Corina/0000-0002-7539-9453; Raul, Mihailov/0000-0001-7081-9490
CR Abbitt D, 2021, J SURG CASE REP, V2021, DOI 10.1093/jscr/rjab479
   Alhalabi MM, 2023, MEDICINE, V102, DOI 10.1097/MD.0000000000033699
   asahq.org, STATEMENT ASA PHYS S
   Cereatti F, 2020, WORLD J GASTROENTERO, V26, DOI 10.3748/wjg.v26.i29.4198
   Chevallay M, 2023, SURG ENDOSC, V37, P1846, DOI 10.1007/s00464-022-09686-w
   Ciuntu B.M., 2018, Med. Surg. J, V122, P4
   Ciuntu B.M., 2020, J. Surg, V16, P301
   Coccolini F, 2023, WORLD J EMERG SURG, V18, DOI 10.1186/s13017-023-00509-4
   Coco Danilo, 2022, Maedica (Bucur), V17, P692, DOI [10.26574/maedica.2022.17.3.692, 10.26574/maedica.2022.17.3.692]
   Costa G, 2023, SURG ENDOSC, V37, P5137, DOI 10.1007/s00464-023-09998-5
   Dadfar A, 2020, WORLD J GASTROENTERO, V26, P5302, DOI 10.3748/wjg.v26.i35.5302
   de Moura Diogo T H, 2018, Curr Treat Options Gastroenterol, V16, P386, DOI [10.1007/s11938-018-0199-6, 10.1007/s11938-018-0199-6]
   de Moura Diogo Turiani Hourneaux, 2021, VideoGIE, V6, P523, DOI [10.1016/j.vgie.2021.08.002, 10.1016/j.vgie.2021.08.002]
   Ding W, 2023, MEDICINE, V102, DOI 10.1097/MD.0000000000033769
   de Moura DTH, 2019, WORLD J GASTRO ENDOS, V11, P329, DOI 10.4253/wjge.v11.i5.329
   Hu XY, 2023, GELS-BASEL, V9, DOI 10.3390/gels9040282
   Kouladouros K, 2023, WORLD J GASTRO ENDOS, V15, P420, DOI 10.4253/wjge.v15.i6.420
   Liu JP, 2023, BMC SURG, V23, DOI 10.1186/s12893-023-02005-7
   Loske G, 2019, ENDOSC INT OPEN, V7, pE1424, DOI 10.1055/a-0972-9660
   Mandarino FV, 2023, LIFE-BASEL, V13, DOI 10.3390/life13020287
   Pattynama LMD, 2023, ENDOSCOPY, V55, P1019, DOI 10.1055/a-2102-1691
   Pines G, 2018, J LAPAROENDOSC ADV S, V28, P33, DOI 10.1089/lap.2017.0318
   Singh RR, 2018, TRANSL GASTROENT HEP, V3, DOI 10.21037/tgh.2018.10.09
   Staudenmann D, 2022, THER ADV GASTROINTES, V15, DOI 10.1177/26317745221076705
   Tarasconi A, 2020, WORLD J EMERG SURG, V15, DOI 10.1186/s13017-019-0283-9
   Tulinsky L, 2022, CUREUS J MED SCIENCE, V14, DOI 10.7759/cureus.30926
   Uhe I, 2023, FRONT SURG, V10, DOI 10.3389/fsurg.2023.1206828
   Umbu L, 2023, J SURG CASE REP, V2023, DOI 10.1093/jscr/rjad368
   Weledji EP, 2020, FRONT SURG, V7, DOI 10.3389/fsurg.2020.573901
   Yalçin M, 2022, ULUS TRAVMA ACIL CER, V28, P1558, DOI 10.14744/tjtes.2022.85686
   Yanamaladoddi VR, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.44522
   Yurttas C, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-14278-8
NR 32
TC 3
Z9 3
U1 4
U2 13
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD JAN
PY 2024
VL 13
IS 2
AR 470
DI 10.3390/jcm13020470
PG 11
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA GF9O5
UT WOS:001151370400001
PM 38256604
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Liu, ZW
   Zhang, WJ
   Zhang, BY
   Ma, LH
   Zhou, F
   Hu, ZY
   Jie, X
   Gao, H
   Zhu, XH
AF Liu, Zhiwan
   Zhang, Wenjun
   Zhang, Boyu
   Ma, Linhao
   Zhou, Feng
   Hu, Zheyuan
   Jie, Xiang
   Gao, Hong
   Zhu, Xiaohai
TI Toxic shock syndrome complicated with symmetrical peripheral gangrene
   after liposuction and fat transfer: a case report and literature review
SO BMC INFECTIOUS DISEASES
LA English
DT Review
DE Liposuction; Toxic shock syndrome; Multiple organ dysfunction syndrome;
   Necrotizing soft tissue infection; Symmetrical peripheral gangrene
ID STREPTOCOCCUS; MANAGEMENT
AB Background Liposuction is one of the most commonly performed aesthetic procedures. Toxic shock syndrome(TSS) is a rare, life-threatening complication. The incidence rate of TSS is very low in the plastic surgery field, especially after liposuction and fat transfer. Case presentation A 23-year-old female patient was transferred to our emergency department from an aesthetic clinic with sepsis shock features after received liposuction and fat transfer. The patient underwent TSS, disseminated intravascular coagulation(DIC), multiple organ dysfunction syndrome (MODS), symmetrical peripheral gangrene (SPG), and necrotizing soft tissue infection of the buttocks in the next 10 days. Authors used a series of debridement and reconstructive surgery including vacuum sealing drainage (VSD) treatment, artificial dermis grafts,split-thickness skin grafts, amputation surgeries when her vital signs were stable. The patient experienced desquamation of the hand on the 26th day. The skin grafts survived and the function of both fingers and toes recovered. She was discharged 2 months after admission and was in good health. Conclusion TSS is extremely rare in the field of liposuction and autologous fat transfer. The mortality rate of TSS is very high. Early diagnosis and operative treatment, as well as correction of systemic abnormalities, are the important keys to save a patient's life.
C1 [Liu, Zhiwan; Zhang, Wenjun; Hu, Zheyuan; Jie, Xiang; Gao, Hong; Zhu, Xiaohai] Shanghai Changzheng Hosp, Dept Plast Surg, 415 Fengyang Rd, Shanghai 200003, Peoples R China.
   [Zhang, Boyu; Ma, Linhao] Shanghai Changzheng Hosp, Dept Emergency, Shanghai, Peoples R China.
   [Zhou, Feng] Shanghai Tongji Hosp, Dept Plast Surg, Shanghai, Peoples R China.
C3 Naval Medical University; Naval Medical University
RP Zhu, XH (通讯作者)，Shanghai Changzheng Hosp, Dept Plast Surg, 415 Fengyang Rd, Shanghai 200003, Peoples R China.
EM drzxh@qq.com
RI zhu, xiaohai/HDO-0462-2022; Jie, Xiang Jie/PQA-2777-2026; Hu,
   Zheyuan/PLR-2482-2026; Ma, Linhao/IUP-2638-2023
OI zhang, wenjun/0000-0001-8264-0754; Ma, Linhao/0000-0001-5846-4308
CR Albano MN, 2018, ANN MED SURG, V35, P103, DOI 10.1016/j.amsu.2018.09.025
   Baxter M, 2017, EMERG INFECT DIS, V23, P127, DOI 10.3201/eid2301.161009
   Bell Michael Sg, 2009, Can J Plast Surg, V17, pe29
   BRESLER MJ, 1983, WESTERN J MED, V139, P710
   Centers for Disease Control and Prevention, TOX SHOCK SYNDR OTH
   De la Fuente JRO, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.8617
   Ezzeddine H, 2018, AESTHET PLAST SURG, V42, P384, DOI 10.1007/s00266-017-1058-x
   Ghosh SK, 2010, J EUR ACAD DERMATOL, V24, P214, DOI 10.1111/j.1468-3083.2009.03329.x
   GOODWIN JN, 1974, ARCH SURG-CHICAGO, V108, P780
   Gottlieb M, 2018, J EMERG MED, V54, P807, DOI 10.1016/j.jemermed.2017.12.048
   GRAHAM DR, 1995, CLIN INFECT DIS, V20, P895, DOI 10.1093/clinids/20.4.895
   Grazer FM, 2000, PLAST RECONSTR SURG, V105, P436, DOI 10.1097/00006534-200001000-00070
   Hisanaga K, 2019, ANN PLAS SURG, V83, P359, DOI 10.1097/SAP.0000000000001868
   Ikebe T, 2015, J INFECT CHEMOTHER, V21, P207, DOI 10.1016/j.jiac.2014.12.002
   Jarrahy Reza, 2007, Aesthet Surg J, V27, P162, DOI 10.1016/j.asj.2007.01.007
   Jiang JL, 2017, TZU CHI MED J, V29, P121, DOI 10.4103/tcmj.tcmj_25_17
   Kim YH, 2011, PLAST RECONSTR SURG, V127, P863, DOI 10.1097/PRS.0b013e318200afbf
   Korman TM, 2004, J CLIN MICROBIOL, V42, P2866, DOI 10.1128/JCM.42.6.2866-2869.2004
   Lehnhardt Marcus, 2008, Plast Reconstr Surg, V121, p396e, DOI 10.1097/PRS.0b013e318170817a
   Madhusudhan Thayur R, 2007, J Med Case Rep, V1, P118, DOI 10.1186/1752-1947-1-118
   MOLOS MA, 1985, ARCH DERMATOL, V121, P1057, DOI 10.1001/archderm.121.8.1057
   Montrief T, 2020, WEST J EMERG MED, V21, P179, DOI 10.5811/westjem.2020.6.46415
   Rai S P, 2008, Med J Armed Forces India, V64, P181, DOI 10.1016/S0377-1237(08)80076-7
   REINGOLD AL, 1982, LANCET, V1, P1
   Rhee C A, 1994, Aesthetic Plast Surg, V18, P161, DOI 10.1007/BF00454477
   SHANDS KN, 1980, NEW ENGL J MED, V303, P1436, DOI 10.1056/NEJM198012183032502
   Shenoy R, 2013, INDIAN J SURG, V75, pS163, DOI 10.1007/s12262-012-0576-7
   Shimbo K, 2015, CASE REP PLAST SURG, V2, P53, DOI 10.3109/23320885.2015.1041529
   Sims KD, 2006, EUR J CLIN MICROBIOL, V25, P208, DOI 10.1007/s10096-006-0106-2
   Sinave C, 2002, CLIN INFECT DIS, V35, P1441, DOI 10.1086/344464
   Stephan PJ, 2010, AESTHET SURG J, V30, P83, DOI 10.1177/1090820X10362728
   Suárez-Amor O, 2009, ACTAS DERMO-SIFILOGR, V100, P334, DOI 10.1016/S0001-7310(09)70833-6
   Tang W M, 2000, Clin Infect Dis, V31, pE15, DOI 10.1086/318148
   TODD J, 1978, LANCET, V2, P1116
   Ulu BU, 2021, J CLIN APHERESIS, V36, P649, DOI 10.1002/jca.21893
   Vongpaisarnsin K, 2015, INT J LEGAL MED, V129, P815, DOI 10.1007/s00414-014-1056-3
   Wilkins AL, 2017, J INFECTION, V74, pS147, DOI 10.1016/S0163-4453(17)30206-2
   Yoshida M, 2016, INTERNAL MED, V55, P3211, DOI 10.2169/internalmedicine.55.6787
   You JS, 2015, KOREAN J RADIOL, V16, P1197
   Young K, 2016, AM J MED SCI, V352, P86, DOI 10.1016/j.amjms.2016.04.002
NR 40
TC 6
Z9 9
U1 2
U2 15
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
EI 1471-2334
J9 BMC INFECT DIS
JI BMC Infect. Dis.
PD NOV 6
PY 2021
VL 21
IS 1
AR 1137
DI 10.1186/s12879-021-06777-2
PG 6
WC Infectious Diseases
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases
GA WS2OK
UT WOS:000715026400001
PM 34742247
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Xu, XF
   Zhou, YW
   Huang, Y
   Le, Q
   Lin, LL
   Yu, ZW
AF Xu, Xiaofeng
   Zhou, Yiwen
   Huang, Ying
   Le, Qian
   Lin, Lili
   Yu, Zhuowen
TI Nursing Management of Abdominal Wound Dehiscence of an Infant With
   Severe Undernutrition and Peristomal Moisture-Associated Dermatitis
   After Ileostomy Closure A Case Study
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Abdominal wound dehiscence; Nutrition; Peristomal moisture-associated
   dermatitis; Stomal closure; Wound healing
ID RISK-FACTORS; SKIN
AB BACKGROUND: Abdominal wound dehiscence (AWD) is a costly postoperative complication; its management is particularly challenging for WOC nurses when it occurs secondary to an ostomy closure.
   CASE: We present a case of AWD secondary to ileostomy closure in Baby Q, a 9-month 19-day-old female infant. A silver wound contact dressing was used on her dehisced wound followed by negative pressure wound therapy and adhesive tape to pull the wound edge together and promote granulation. We used a combination of enteral nutrition, parenteral nutrition, total parenteral nutrition, and total enteral nutrition adjusting the feeding plan stepwise according to her nutritional status.
   CONCLUSIONS: Malnutrition and severe peristomal skin complications may contribute to the risk of AWD in infants undergoing reversal of a temporary ostomy. Assessing and treating nutritional status and peristomal skin is imperative before performing ostomy closure.
C1 [Xu, Xiaofeng; Zhou, Yiwen; Huang, Ying; Le, Qian; Lin, Lili; Yu, Zhuowen] Fudan Univ, Childrens Natl Med Ctr, Dept Gastroenterol, Childrens Hosp, Shanghai, Peoples R China.
C3 Fudan University
RP Yu, ZW (通讯作者)，Fudan Univ, Childrens Hosp, Dept Gastroenterol, Shanghai 201100, Peoples R China.
EM xxf1065@163.com; Zhouyiwenapril@gmail.com; lele-306@163.com;
   57736174@qq.com; yzw100@126.com
RI lin, lili/JKH-7869-2023
CR Ambe PC, 2018, DTSCH ARZTEBL INT, V115, P182, DOI 10.3238/arztebl.2018.0182
   Colwell JC, 2019, J WOUND OSTOMY CONT, V46, P497, DOI 10.1097/WON.0000000000000599
   Colwell JC, 2011, J WOUND OSTOMY CONT, V38, P541, DOI 10.1097/WON.0b013e31822acd95
   Denys A, 2021, HERNIA, V25, P449, DOI 10.1007/s10029-020-02294-4
   Dissemond J, 2021, J DTSCH DERMATOL GES, V19, P815, DOI [10.1111/ddg.14388_g, 10.1111/ddg.14388]
   Duan SX, 2021, ANN MED, V53, P900, DOI 10.1080/07853890.2021.1938661
   Ducey J, 2022, ARCH DIS CHILD-FETAL, V107, P448, DOI 10.1136/archdischild-2021-322040
   Harries RL, 2016, INT WOUND J, V13, P8, DOI 10.1111/iwj.12662
   Jemec GB, 2011, BRIT J DERMATOL, V164, P330, DOI 10.1111/j.1365-2133.2010.10093.x
   McNichol L., 2022, J WOUND OSTOMY CONT, V49, P235, DOI [10.1097/WON.0000000000000873, DOI 10.1097/WON.0000000000000873]
   Nagano M, 2019, J WOUND OSTOMY CONT, V46, P137, DOI 10.1097/WON.0000000000000491
   Ratliff CR, 2021, J WOUND OSTOMY CONT, V48, P219, DOI 10.1097/WON.0000000000000758
   Salvadalena G, 2020, J WOUND OSTOMY CONT, V47, P357, DOI 10.1097/WON.0000000000000666
   Temesgen F, 2021, ETHIOP J HEALTH SCI, V31, P111, DOI 10.4314/ejhs.v31i1.13
   Timmer AS, 2022, BMJ OPEN, V12, DOI 10.1136/bmjopen-2021-054534
   van Ramshorst GH, 2009, WORLD J SURG, V33, P1509, DOI 10.1007/s00268-009-0058-7
   Waldhausen JHT, 2000, J AM COLL SURGEONS, V190, P688, DOI 10.1016/S1072-7515(00)00284-2
   Werner JM, 2022, FRONT SURG, V9, DOI 10.3389/fsurg.2022.821509
   Yang H, 2021, ADV SKIN WOUND CARE, V34, P309, DOI 10.1097/01.ASW.0000744336.73981.8f
NR 19
TC 2
Z9 3
U1 3
U2 13
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JUL-AUG
PY 2023
VL 50
IS 4
BP 331
EP 336
DI 10.1097/WON.0000000000000987
PG 6
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA S6IQ3
UT WOS:001072183400012
PM 37467414
DA 2026-07-24
ER

PT J
AU Beltran, MJ
   Blair, JA
   Rathbone, CR
   Hsu, JR
AF Beltran, Michael J.
   Blair, James A.
   Rathbone, Christopher R.
   Hsu, Joseph R.
TI The Gradual Expansion Muscle Flap
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE shortening and angulation; Taylor Spatial Frame; III-B tibia fracture;
   flap coverage
ID SEVERE OPEN FRACTURES; SKELETAL-MUSCLE; THERAPY; RECONSTRUCTION;
   MANAGEMENT; COVERAGE
AB High-energy open fractures of the tibia have traditionally been fraught with challenges to include bone comminution or loss, soft tissue loss, nonunion, and infection. A number of techniques have been implemented to treat the severe soft tissue loss typically involving the anteromedial surface of the tibia to include wet-to-dry dressings or Papineau techniques, negative pressure wound therapy, acellular dermal matrices, and rotational or free tissue transfer with Masquelet technique, primary shortening, and distraction osteogenesis to address bone loss. We present a novel technique and subsequent case series that obviates the need of free tissue transfer while treating high-energy type IIIB open tibia fractures by performing an acute shortening and angulation of the tibia and rotational muscle flap coverage and split-thickness skin grafting of the soft tissue defect. Distraction histiogenesis with circular external fixation is then used to correct the residual osseous deformity while stretching the rotational muscle flap.
C1 [Beltran, Michael J.; Blair, James A.] San Antonio Mil Med Ctr, Dept Orthopaed & Rehabil, San Antonio, TX 78234 USA.
   [Rathbone, Christopher R.; Hsu, Joseph R.] US Army Inst Surg Res, San Antonio, TX USA.
C3 Brooke Army Medical Center; United States Department of Defense; United
   States Army
RP Beltran, MJ (通讯作者)，San Antonio Mil Med Ctr, Dept Orthopaed & Rehabil, 3851 Roger Brooke Dr, San Antonio, TX 78234 USA.
EM michael.beltran@amedd.army.mil
RI Blair, James/MIP-0917-2025
OI Hsu, Joseph/0000-0001-9341-2554; Beltran, Michael/0000-0002-3069-3659
FU Combat Casualty Research Program; Major Extremity Trauma Research
   Consortium
FX J. R. Hsu receives institutional research support from the Geneva
   Foundation, is a board member for the Society of Military Orthopaedic
   Surgeons, and receives grant funding through the Combat Casualty
   Research Program and Major Extremity Trauma Research Consortium.
CR Archdeacon MT, 2006, J ORTHOP TRAUMA, V20, P134, DOI 10.1097/01.bot.0000184147.82824.7c
   Beltran Michael J, 2010, J Surg Orthop Adv, V19, P23
   Blair JA, FOOT ANKLE IN PRESS
   Bosse MJ, 2002, NEW ENGL J MED, V347, P1924, DOI 10.1056/NEJMoa012604
   Burns TC, 2010, J ORTHOP TRAUMA, V24, P697, DOI 10.1097/BOT.0b013e3181d048b8
   CAUDLE RJ, 1987, J BONE JOINT SURG AM, V69A, P801, DOI 10.2106/00004623-198769060-00002
   Chim H, 2011, PLAST RECONSTR SURG, V127, P2364, DOI 10.1097/PRS.0b013e318213a141
   CIERNY G, 1994, CLIN ORTHOP RELAT R, P118
   CIERNY G, 1983, CLIN ORTHOP RELAT R, P54
   Day CS, 1997, J ORTHOPAED RES, V15, P227, DOI 10.1002/jor.1100150211
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   DeLong WG, 1999, J TRAUMA, V46, P1049, DOI 10.1097/00005373-199906000-00012
   Duman H, 2001, ANN PLAS SURG, V46, P108, DOI 10.1097/00000637-200102000-00003
   Gold SM, 2005, J ORTHOP TRAUMA, V19, P10, DOI 10.1097/00005131-200501000-00003
   Gopal S, 2000, J BONE JOINT SURG BR, V82B, P959, DOI 10.1302/0301-620X.82B7.10482
   Helgeson MD, 2007, J ORTHOP TRAUMA, V21, P394, DOI 10.1097/BOT.0b013e318070c028
   Herscovici D, 2003, J ORTHOP TRAUMA, V17, P683, DOI 10.1097/00005131-200311000-00004
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P249, DOI 10.1097/00003086-198901000-00038
   ILIZAROV GA, 1989, CLIN ORTHOP RELAT R, P263
   Kakar S, 2007, J ORTHOP TRAUMA, V21, P153, DOI 10.1097/BOT.0b013e3180336923
   KIM KHA, 1993, PLAST RECONSTR SURG, V92, P710, DOI 10.1097/00006534-199309001-00022
   Laughlin R T, 1993, J Orthop Trauma, V7, P123, DOI 10.1097/00005131-199304000-00004
   Masquelet A C, 2000, Ann Chir Plast Esthet, V45, P346
   Masquelet AC, 2010, ORTHOP CLIN N AM, V41, P27, DOI 10.1016/j.ocl.2009.07.011
   MAURO A, 1961, J BIOPHYS BIOCHEM CY, V9, P493, DOI 10.1083/jcb.9.2.493
   Nho SJ, 2006, J ORTHOP TRAUMA, V20, P419, DOI 10.1097/00005131-200607000-00010
   Owens JG, 2011, J TRAUMA, V71, pS120, DOI 10.1097/TA.0b013e3182219225
   Patzkowski Jeanne C, 2011, J Surg Orthop Adv, V20, P8
   Pollak AN, 2000, J BONE JOINT SURG AM, V82A, P1681, DOI 10.2106/00004623-200012000-00001
   Rozbruch S.R., 2006, Limb lengthening and reconstruction surgery, V1st ed.
   SCHUMACHER B, 1994, ACTA ORTHOP SCAND, V65, P647, DOI 10.3109/17453679408994623
   SOLA OM, 1973, EXP NEUROL, V41, P76, DOI 10.1016/0014-4886(73)90182-9
   SONNTAG BV, 1995, ANN PLAS SURG, V34, P336, DOI 10.1097/00000637-199503000-00020
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Stinner DJ, 2010, MIL MED, V175, P1027, DOI 10.7205/MILMED-D-10-00102
   Stinner DJ, 2012, J TRAUMA ACUTE CARE, V72, P1062
   TORNETTA P, 1994, J BONE JOINT SURG BR, V76B, P13, DOI 10.1302/0301-620X.76B1.8300656
   Tosenovsky P, 2003, EUR J VASC ENDOVASC, V26, P562, DOI 10.1016/S1078-5884(03)00147-3
   Tsujimura T, 2006, J ORTHOP SCI, V11, P185, DOI 10.1007/s00776-005-0991-8
   Watson J Tracy, 2006, J Am Acad Orthop Surg, V14, pS168
   Watson JT, 1995, CLIN ORTHOP RELAT R, V315, P128
NR 42
TC 12
Z9 16
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD JAN
PY 2014
VL 28
IS 1
BP E15
EP E20
DI 10.1097/BOT.0b013e3182940b65
PG 6
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA 276EY
UT WOS:000328732400007
PM 23571291
DA 2026-07-24
ER

PT J
AU Patel, RM
   Nagle, DJ
AF Patel, Ronak M.
   Nagle, Daniel J.
TI Nonoperative Management of Scleroderma of the Hand With Tadalafil and
   Subatmospheric Pressure Wound Therapy: Case Report
SO JOURNAL OF HAND SURGERY-AMERICAN VOLUME
LA English
DT Article
DE Negative pressure wound therapy; scleroderma
ID SYSTEMIC-SCLEROSIS; SILDENAFIL
AB Scleroderma, or systemic sclerosis (SS), is an autoimmune disease leading to ischemic fibrosis and widespread collagen deposition, invariably affecting the hands. Optimized medical management remains the mainstay of therapy for SS. Surgery can be considered in refractory or severely disabling cases. However, microvascular insufficiency and fibrosis can lead to wound complications and, ultimately, amputation. We present the case of a 61-year-old man with a known history of scleroderma who presented with pain, chronic infection, and ulcerations in the left hand. Initially, amputation seemed a reasonable intervention. After medical optimization with tadalafil, his ulcerations persisted. Instead of amputation, we applied a subatmospheric pressure wound therapy device to his hand. In 4 months, his wounds had healed, there was no evidence of infection, and no digits were amputated. (J Hand Surg 2012;37A:803-806. Copyright (C) 2012 by the American Society for Surgery of the Hand. All rights reserved.)
C1 [Patel, Ronak M.; Nagle, Daniel J.] Northwestern Univ, Feinberg Sch Med, Dept Orthopaed Surg, Chicago Ctr Surg Hand, Chicago, IL 60611 USA.
C3 Northwestern University; Feinberg School of Medicine
RP Patel, RM (通讯作者)，Northwestern Univ, Feinberg Sch Med, Dept Orthopaed Surg, Chicago Ctr Surg Hand, 401 E Ontario St,1707, Chicago, IL 60611 USA.
EM rmpatel7@gmail.com
CR Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   BARRY M, 1983, ARTHRITIS RHEUM, V26, P1041, DOI 10.1002/art.1780260816
   Bovill E, 2008, INT WOUND J, V5, P511, DOI 10.1111/j.1742-481X.2008.00437.x
   Chung Lorinda, 2007, J Dtsch Dermatol Ges, V5, P460, DOI 10.1111/j.1610-0387.2007.06279.x
   Colglazier CL, 2005, J RHEUMATOL, V32, P2440
   Gore J, 2005, ANN RHEUM DIS, V64, P1387, DOI 10.1136/ard.2004.034488
   Kelm J, 2009, INT J MED SCI, V6, P241
   Koehler C, 2008, J TRAUMA, V65, P722, DOI 10.1097/01.ta.0000249295.82527.19
   LEROY EC, 1988, J RHEUMATOL, V15, P202
   Markus YM, 2006, J RHEUMATOL, V33, P1694
   Melone Charles P. Jr., 1999, Current Opinion in Rheumatology, V11, P514, DOI 10.1097/00002281-199911000-00013
   Mendonca Derick A, 2006, Int Wound J, V3, P261, DOI 10.1111/j.1742-481X.2006.00266.x
   Potério J, 1998, J RHEUMATOL, V25, P1540
   Prasarn Mark L, 2009, Am J Orthop (Belle Mead NJ), V38, P559
   Shenoy PD, 2010, RHEUMATOLOGY, V49, P2420, DOI 10.1093/rheumatology/keq291
   Webb LX, 2001, UNFALLCHIRURG, V104, P918, DOI 10.1007/PL00002776
NR 16
TC 9
Z9 9
U1 0
U2 3
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0363-5023
EI 1531-6564
J9 J HAND SURG-AM
JI J. Hand Surg.-Am. Vol.
PD APR
PY 2012
VL 37A
IS 4
BP 803
EP 806
DI 10.1016/j.jhsa.2011.12.030
PG 4
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA 925JA
UT WOS:000302756300027
PM 22305739
DA 2026-07-24
ER

PT J
AU Dobke, MK
   Nguyen, D
   Trott, SA
AF Dobke, MK
   Nguyen, D
   Trott, SA
TI A novel approach to acute infection of the glenohumeral joint following
   rotator cuff repair - A case series
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Article
AB Glenohumeral joint infection (GJI) is a difficult-to-treat complication following rotator cuff repair (RCR). The authors present a case series illustrating the management of GJI with debridement, drainage, and simultaneous joint sealing with negative pressure wound therapy (NPWT, V.A.C.(R) Therapy (TM) System, KCl, San Antonio, Tex) followed by muscle flap coverage. Six patients with acute Staphylococcus aureus infection and spontaneous purulent drainage following arthroscopic RCR for post-traumatic problems were treated. Patients underwent serial pulse-lavage debridements through a deltoid-sparing incision followed by NPWT. Closed-system drainage obviated the need for dressing the wound with exposed joint. Grain stain and culture were negative upon second exploration. Within 2 weeks, the joint was covered with a muscle flap. Use of NPWT allowed relatively quick resolution of infection without secondary joint damage due to superinfection or desiccation. Reconstruction of the soft tissue over the joint with a muscle flap resulted in durable coverage without fistula formation or unstable scars.
C1 Univ Calif San Diego, Dept Surg, Div Plast Surg, San Diego, CA 92103 USA.
C3 University of California System; University of California San Diego
RP Dobke, MK (通讯作者)，Univ Calif San Diego, Dept Surg, Div Plast Surg, 200 W Arbor Dr, San Diego, CA 92103 USA.
CR Argenta LC, 2000, ANN PLAS SURG, V45, P335, DOI 10.1097/00000637-200045030-00020
   Bigliani L U, 1991, Orthop Rev, V20, P743
   Feeney MS, 2003, J SHOULDER ELB SURG, V12, P20, DOI 10.1067/mse.2003.128565
   Herrera MF, 2002, J SHOULDER ELB SURG, V11, P605, DOI 10.1067/mse.2002.127302
   *KIN CONC INC, 2001, VAC REC GUID US MAN, P1
   MCCRAW JB, 1986, MCCRAW ARNOLDS ATLAS, P157
   Mirzayan R, 2000, J BONE JOINT SURG AM, V82A, P1115, DOI 10.2106/00004623-200008000-00008
   Settecerri JJ, 1999, J SHOULDER ELB SURG, V8, P1, DOI 10.1016/S1058-2746(99)90045-9
   Song DH, 2003, PLAST RECONSTR SURG, V111, P92, DOI 10.1097/01.PRS.0000037686.14278.6A
NR 9
TC 3
Z9 3
U1 0
U2 0
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
EI 1943-2704
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUN
PY 2005
VL 17
IS 6
BP 137
EP 140
PG 4
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 939FH
UT WOS:000230057300002
DA 2026-07-24
ER

PT J
AU Hernandez, J
   Rosenthal, AA
AF Hernandez, Jennifer
   Rosenthal, Andrew A.
TI Hemipelvectomy as a Salvage Procedure in Massive Pelvic Trauma
SO AMERICAN SURGEON
LA English
DT Article
DE trauma; pelvic injury; mangled extremity severity score; critical care
AB "Pedestrian struck by train" represents one of the highest magnitude blunt force traumas. Despite the severity of injuries, these patients can have good outcomes. A 25-year-old male presented after being struck by a train. He had several injuries, including extensive complex pelvic fractures, right external iliac artery and vein laceration, and right femur and tibia fracture. He was taken to the operating room for damage control surgery and attempted revascularization of the right lower extremity. The extremity became ischemic and required above knee amputation followed by hip disarticulation and hemipelvectomy. His pelvic wounds were treated with negative pressure wound therapy and gradually closed. He was eventually discharged to a rehab facility for continued recovery. This case highlights the interventions that allowed a young man who was struck by a train to survive. He improved significantly since undergoing hemipelvectomy, indicating that severe pelvic injuries from high energy trauma may necessitate hemipelvectomy.
C1 [Hernandez, Jennifer; Rosenthal, Andrew A.] Mem Healthcare Syst, Dept Surg, 3501 Johnson St, Hollywood, FL 33021 USA.
RP Hernandez, J (通讯作者)，Mem Healthcare Syst, Dept Surg, 3501 Johnson St, Hollywood, FL 33021 USA.
EM jennifhernandez@mhs.net
OI Klein, Jennifer Hernandez/0000-0001-8836-4455
CR Burkhardt M, 2005, UNFALLCHIRURG, V108, P812, DOI 10.1007/s00113-005-0997-x
   Loja MN, 2017, J TRAUMA ACUTE CARE, V82, P518, DOI 10.1097/TA.0000000000001339
NR 2
TC 1
Z9 1
U1 0
U2 0
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0003-1348
EI 1555-9823
J9 AM SURGEON
JI Am. Surg.
PD JUL
PY 2022
VL 88
IS 7
BP 1568
EP 1569
AR 00031348221084939
DI 10.1177/00031348221084939
EA APR 2022
PG 2
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 2C7GT
UT WOS:000787629400001
PM 35465736
DA 2026-07-24
ER

PT J
AU Han, G
   Ceilley, R
AF Han, George
   Ceilley, Roger
TI Chronic Wound Healing: A Review of Current Management and Treatments
SO ADVANCES IN THERAPY
LA English
DT Review
DE Biofilms; Chronic wounds; Growth factors; Hyperbaric oxygen; Negative
   pressure wound therapy; Skin infection; Skin substitutes; Wound
   dressings; Wound healing
ID HYPERBARIC-OXYGEN THERAPY; CADEXOMER IODINE; RANDOMIZED TRIAL;
   CLINICAL-TRIAL; FOOT ULCERS; FETAL SKIN; VITAMIN-E; CARE; COLLAGEN;
   PROPHYLAXIS
AB Wound healing is a complex, highly regulated process that is critical in maintaining the barrier function of skin. With numerous disease processes, the cascade of events involved in wound healing can be affected, resulting in chronic, non-healing wounds that subject the patient to significant discomfort and distress while draining the medical system of an enormous amount of resources. The healing of a superficial wound requires many factors to work in concert, and wound dressings and treatments have evolved considerably to address possible barriers to wound healing, ranging from infection to hypoxia. Even optimally, wound tissue never reaches its pre-injured strength and multiple aberrant healing states can result in chronic non-healing wounds. This article will review wound healing physiology and discuss current approaches for treating a wound.
C1 [Han, George] Icahn Sch Med Mt Sinai, New York, NY 10029 USA.
   [Ceilley, Roger] Univ Iowa, Iowa City, IA USA.
C3 Icahn School of Medicine at Mount Sinai; University of Iowa
RP Han, G (通讯作者)，Icahn Sch Med Mt Sinai, New York, NY 10029 USA.
EM george.han@mountsinai.org
OI Han, George/0000-0003-3302-5098
CR ARMSTRONG DG, 1995, J AM PODIAT MED ASSN, V85, P533, DOI 10.7547/87507315-85-10-533
   Badiavas EV, 2003, ARCH DERMATOL, V139, P510, DOI 10.1001/archderm.139.4.510
   BARNETT SE, 1987, ANN ROY COLL SURG, V69, P153
   Barrientos S, 2008, WOUND REPAIR REGEN, V16, P585, DOI 10.1111/j.1524-475X.2008.00410.x
   Beele H, 2010, INT WOUND J, V7, P262, DOI 10.1111/j.1742-481X.2010.00669.x
   Brem H, 2007, MOL MED, V13, P30, DOI 10.2119/2006-00054.Brem
   Brem H, 2007, J CLIN INVEST, V117, P1219, DOI 10.1172/JCI32169
   BRESLOW RA, 1993, J AM GERIATR SOC, V41, P357, DOI 10.1111/j.1532-5415.1993.tb06940.x
   Christman AL, 2011, J INVEST DERMATOL, V131, P2121, DOI 10.1038/jid.2011.176
   Cullen B, 2002, WOUND REPAIR REGEN, V10, P16, DOI 10.1046/j.1524-475X.2002.10703.x
   Degen KE, 2012, BIRTH DEFECTS RES C, V96, P258, DOI 10.1002/bdrc.21019
   Draelos ZD, 2011, J AM ACAD DERMATOL, V64, pS23, DOI 10.1016/j.jaad.2010.11.010
   Driver VR, 2015, WOUND REPAIR REGEN, V23, P891, DOI 10.1111/wrr.12357
   Dziewulski P, 2011, HDB OF BURNS, V1, P291
   EHRLICH HP, 1972, ANN SURG, V175, P235, DOI 10.1097/00000658-197202000-00013
   Emmerson E, 2012, J INVEST DERMATOL, V132, P2838, DOI 10.1038/jid.2012.228
   Fonder MA, 2008, J AM ACAD DERMATOL, V58, P185, DOI 10.1016/j.jaad.2007.08.048
   Galeano M, 2001, SURGERY, V129, P467, DOI 10.1067/msy.2001.112072
   GREENWALD DP, 1990, J SURG RES, V49, P98, DOI 10.1016/0022-4804(90)90117-K
   Gurtner GC, 2008, NATURE, V453, P314, DOI 10.1038/nature07039
   Han G, 2012, AM J PATHOL, V180, P1465, DOI 10.1016/j.ajpath.2011.12.013
   Hanft Jason R, 2002, J Foot Ankle Surg, V41, P291
   HAUKIPURO K, 1991, ANN SURG, V213, P75, DOI 10.1097/00000658-199101000-00013
   Hunt TK, 1997, SURG CLIN N AM, V77, P587, DOI 10.1016/S0039-6109(05)70570-3
   Jackson WM, 2012, STEM CELL RES THER, V3, DOI 10.1186/scrt111
   Jones V, 2006, BMJ-BRIT MED J, V332, P777, DOI 10.1136/bmj.332.7544.777
   Ke QD, 2006, MOL PHARMACOL, V70, P1469, DOI 10.1124/mol.106.027029
   Kranke P, 2004, Cochrane Database Syst Rev, pCD004123
   Langer A, 2009, BMC HEALTH SERV RES, V9, DOI 10.1186/1472-6963-9-115
   Langford JH, 1997, ANN PHARMACOTHER, V31, P559, DOI 10.1177/106002809703100506
   Larson BJ, 2010, PLAST RECONSTR SURG, V126, P1172, DOI 10.1097/PRS.0b013e3181eae781
   Levender MM, 2012, J AM ACAD DERMATOL, V66, P445, DOI 10.1016/j.jaad.2011.02.005
   Lima MHM, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0036974
   Lipsky BA, 2009, CLIN INFECT DIS, V49, P1541, DOI 10.1086/644732
   Lo DD, 2012, BIRTH DEFECTS RES C, V96, P237, DOI 10.1002/bdrc.21018
   Löndahl M, 2010, DIABETES CARE, V33, P998, DOI 10.2337/dc09-1754
   MacKay Douglas, 2003, Altern Med Rev, V8, P359
   MADDOX JS, 1985, J AM ACAD DERMATOL, V13, P207, DOI 10.1016/S0190-9622(85)70160-0
   Marston WA, 2003, DIABETES CARE, V26, P1701, DOI 10.2337/diacare.26.6.1701
   McFarlin K, 2006, WOUND REPAIR REGEN, V14, P471, DOI 10.1111/j.1743-6109.2006.00153.x
   Miller AC, 2012, J AM ACAD DERMATOL, V66, pE159, DOI 10.1016/j.jaad.2010.06.014
   MOBERG S, 1983, J AM GERIATR SOC, V31, P462, DOI 10.1111/j.1532-5415.1983.tb05117.x
   Mowbray M, 2008, J INVEST DERMATOL, V128, P352, DOI 10.1038/sj.jid.5701096
   MULDER G, 1993, INT J DERMATOL, V32, P304, DOI 10.1111/j.1365-4362.1993.tb04275.x
   Murphy Patrick S, 2012, Plast Surg Int, V2012, P190436, DOI 10.1155/2012/190436
   Newton D J, 2002, J Foot Ankle Surg, V41, P233
   O'Reilly D, 2011, TRIALS, V12, DOI 10.1186/1745-6215-12-69
   Paquette D, 2002, CLIN GERIATR MED, V18, P77, DOI 10.1016/S0749-0690(03)00035-1
   Peppa M, 2009, WOUND REPAIR REGEN, V17, P461, DOI 10.1111/j.1524-475X.2009.00518.x
   Percival SL, 2008, WOUND REPAIR REGEN, V16, P52, DOI 10.1111/j.1524-475X.2007.00350.x
   Prete PE, 1997, LIFE SCI, V60, P505, DOI 10.1016/S0024-3205(96)00688-1
   Reiber GE, 1999, DIABETES CARE, V22, P157, DOI 10.2337/diacare.22.1.157
   Rogers HD, 2010, J AM ACAD DERMATOL, V63, P842, DOI 10.1016/j.jaad.2010.07.029
   RUBERG RL, 1984, SURG CLIN N AM, V64, P705
   SCHNEIDER M, 1983, AM J SURG, V145, P260, DOI 10.1016/0002-9610(83)90075-2
   Seifert AW, 2012, NATURE, V489, P561, DOI 10.1038/nature11499
   Sen CK, 2009, WOUND REPAIR REGEN, V17, P763, DOI 10.1111/j.1524-475X.2009.00543.x
   Sheffield P.J., 1988, Tissue oxygen measurements. Problem Wounds. The Role of Oxygen, P17
   SKOG E, 1983, BRIT J DERMATOL, V109, P77, DOI 10.1111/j.1365-2133.1983.tb03995.x
   Smiell JM, 1999, WOUND REPAIR REGEN, V7, P335, DOI 10.1046/j.1524-475X.1999.00335.x
   Stadelmann WK, 1998, AM J SURG, V176, p39S, DOI 10.1016/S0002-9610(98)00184-6
   Streubel PN, 2012, J AM ACAD ORTHOP SUR, V20, P564, DOI 10.5435/JAAOS-20-09-564
   Taylor SC, 2011, J AM ACAD DERMATOL, V64, pS30, DOI 10.1016/j.jaad.2010.11.009
   Thomas S, 1999, BMJ-BRIT MED J, V318, P807, DOI 10.1136/bmj.318.7186.807
   Trengove N J, 1996, J Wound Care, V5, P277
   Venturi ML, 2005, AM J CLIN DERMATOL, V6, P185, DOI 10.2165/00128071-200506030-00005
   Warriner Robert, 2005, Adv Skin Wound Care, V18 Suppl 1, P2, DOI 10.1097/00129334-200510001-00001
   Wild S, 2004, DIABETES CARE, V27, P1047, DOI 10.2337/diacare.27.5.1047
   Wilgus TA, 2007, OSTOMY WOUND MANAG, V53, P16
   Wu LC, 1999, AM J PATHOL, V154, P301, DOI 10.1016/S0002-9440(10)65276-5
   Wu SC, 2010, J AM PODIAT MED ASSN, V100, P385, DOI 10.7547/1000385
   Wynn TA, 2010, SEMIN LIVER DIS, V30, P245, DOI 10.1055/s-0030-1255354
NR 72
TC 1641
Z9 1965
U1 51
U2 1391
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0741-238X
EI 1865-8652
J9 ADV THER
JI Adv. Ther.
PD MAR
PY 2017
VL 34
IS 3
BP 599
EP 610
DI 10.1007/s12325-017-0478-y
PG 12
WC Medicine, Research & Experimental; Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Research & Experimental Medicine; Pharmacology & Pharmacy
GA EQ3NB
UT WOS:000397978600002
PM 28108895
OA hybrid
HC Y
HP N
DA 2026-07-24
ER

PT J
AU Mabe, L
   Bollero, N
   Olson, MM
AF Mabe, Lainie
   Bollero, Nancy
   Olson, Michelle M.
TI Office-Based Wound Care
SO SURGICAL CLINICS OF NORTH AMERICA
LA English
DT Article
DE Wound healing; Dressings; Debridement; Negative pressure wound therapy;
   Wound infection; Leg ulcer; Peristomal wound; Ambulatory Care
ID LEG ULCERS; MANAGEMENT; DRESSINGS
AB Acute and chronic wounds commonly require outpatient management and surgeons are key members of the patient's care team, often tasked with directing the care plan. It is important not only to understand the issues affecting the healing of all wounds, but also to address the specific needs of the individual patient. Involving the patient and their family in the wound care plan can greatly improve the success of treatment. Standard dressings consist of layers including ointment, contact layer, absorbent layer, contouring layer, and securing layer. More challenging wounds, due to patient comorbidities, complications, or pathology, will often require adjuncts to this basic dressing care. This can be especially difficult in resource-limited environments due to the expense of novel dressing materials. While specialized wound care centers can be helpful in the successful management of complex chronic wounds, they are not readily available to every patient.
C1 [Mabe, Lainie; Olson, Michelle M.] Methodist Hlth Syst, Grad Med Educ Dept, 1441 N Beckley Ave, Dallas, TX 75203 USA.
   [Bollero, Nancy] Carle Hlth Syst, Eugene Greenberg Digest Hlth Inst, 611 W Pk St, Urbana, IL 61801 USA.
RP Olson, MM (通讯作者)，Methodist Hlth Syst, Grad Med Educ Dept, 1441 N Beckley Ave, Dallas, TX 75203 USA.
EM MichelleOlson@mhd.com
CR Agarwal Pawan, 2019, J Clin Orthop Trauma, V10, P845, DOI [10.1016/j.jcot.2019.06.015, 10.1016/j.jcot.2019.06.015]
   Axibal E, 2019, DERMATOL CLIN, V37, P349, DOI 10.1016/j.det.2019.03.005
   Beers EH, 2019, SURG CLIN N AM, V99, P899, DOI 10.1016/j.suc.2019.06.008
   Bigliardi PL, 2017, INT J SURG, V44, P260, DOI 10.1016/j.ijsu.2017.06.073
   Boukovalas S., 2022, Sabiston textbook of surgery the biological basis of modern surgical practice, V21st, P119
   Chadwick P, 2019, J WOUND CARE, V28, P370, DOI 10.12968/jowc.2019.28.6.370
   DesJardins-Park HE, 2022, ADV WOUND CARE, V11, P496, DOI 10.1089/wound.2021.0039
   Federman DG, 2024, WOUND REPAIR REGEN, V32, P619, DOI 10.1111/wrr.13204
   Hankin Cheryl S, 2012, J Manag Care Pharm, V18, P375
   Huang ET, 2023, UHMS hyperbaric medicine indications manual, V15th
   John J, 2022, J WOUND CARE, V31, P969, DOI 10.12968/jowc.2022.31.11.969
   Kavros SJ, 2018, ADV SKIN WOUND CARE, V31, P55, DOI 10.1097/01.ASW.0000527967.10613.87
   Lam G, 2017, ADV SKIN WOUND CARE, V30, P181, DOI 10.1097/01.ASW.0000513089.75457.22
   LeBlanc K, 2019, J WOUND OSTOMY CONT, V46, P125, DOI 10.1097/WON.0000000000000513
   Lionelli GT, 2003, SURG CLIN N AM, V83, P617, DOI 10.1016/S0039-6109(02)00192-5
   Lorenz H.P., 2008, Surgery, P191, DOI [DOI 10.1007/978-0-387-68113-9_10, 10.1007/0-387-22744-x_7, DOI 10.1007/0-387-22744-X_7]
   Millan SB, 2019, AM FAM PHYSICIAN, V100, P298
   O'Donnell TF, 2014, J VASC SURG, V60, p3S, DOI 10.1016/j.jvs.2014.04.049
   Orsted HL, 2010, Wound Care Canada, V8, P6
   Ousey K, 2023, J WOUND CARE, V32, P334, DOI 10.12968/jowc.2023.32.6.334
   Park H, 2010, SURG CLIN N AM, V90, P1181, DOI 10.1016/j.suc.2010.08.001
   Powers JG, 2016, J AM ACAD DERMATOL, V74, P607, DOI 10.1016/j.jaad.2015.08.070
   Schultz GS., 2011, Mechanisms of Vascular Disease: A Reference Book for Vascular Specialists, DOI DOI 10.1017/UPO9781922064004.024
   Steinhagen E, 2017, CLIN COLON RECT SURG, V30, P184, DOI 10.1055/s-0037-1598159
   Tobiano G, 2023, INT WOUND J, V20, P1687, DOI 10.1111/iwj.14030
   Weigelt MA, 2022, ADV WOUND CARE, V11, P330, DOI 10.1089/wound.2020.1319
   Weir GR, 2014, ADV SKIN WOUND CARE, V27, P462, DOI 10.1097/01.ASW.0000453881.34345.08
   Woo KY, 2015, ADV SKIN WOUND CARE, V28, P130, DOI [10.1097/01.asw.0000461342.24513.eb, 10.1097/01.ASW.0000461116.13218.43]
   World Union of Wound Healing Societies Consensus Document, 2018, Surgical wound dehiscence: improving prevention and outcomes
NR 29
TC 1
Z9 1
U1 1
U2 2
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0039-6109
EI 1558-3171
J9 SURG CLIN N AM
JI Surg. Clin.-North Am.
PD AUG
PY 2025
VL 105
IS 4
BP 751
EP 762
DI 10.1016/j.suc.2025.03.012
EA AUG 2025
PG 12
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 5TN8G
UT WOS:001543987000007
PM 40581468
DA 2026-07-24
ER

PT J
AU Guo, MB
   Li, M
AF Guo, Mingbo
   Li, Min
TI Clinical Application of Artificial Dermis Combined with Autologous
   Split-thickness Skin Grafting for Traumatic Soft Tissue Defect
SO INDIAN JOURNAL OF SURGERY
LA English
DT Article
DE Artificial dermis; Autologous split-thickness skin; Trauma; Negative
   pressure wound therapy
AB To evaluate the clinical efficacy of artificial dermis combined with negative-pressure closed-drainage technique and autologous split-thickness skin grafting in repairing soft tissue defects. A case series Analysis was conducted using the clinical data from 26 patients with traumatic soft tissue defects. Patients underwent co-transplantation of artificial dermis and autologous split-thickness skin grafts. Baseline characteristics, diagnostic and treatment data, and outcomes were recorded. Viable thick skin grafts were observed in all 26 patients. Of these, 24 patients achieved complete healing after a single grafting procedure, whereas two patients required additional debridement and grafting for residual small wounds. After a follow-up period of 9.96 +/- 4.11 months, grafts remained well-integrated in situ, with satisfactory cosmetic outcomes. The combined use of artificial dermis, negative-pressure closed-drainage technique, and autologous split-thickness skin grafting represents an effective and straightforward approach for repairing traumatic soft tissue defects.
C1 [Guo, Mingbo; Li, Min] Sunshine Union Hosp, Dept Joint Surg, Weifang 260000, Shandong, Peoples R China.
RP Li, M (通讯作者)，Sunshine Union Hosp, Dept Joint Surg, Weifang 260000, Shandong, Peoples R China.
EM zilong5305@sina.com
FU Weifang Municipal Health Commission [WFWSJK-2024-221]
FX The research leading to these results received funding from [Project
   approved by the Weifang Municipal Health Commission] under Grant
   Agreement No[WFWSJK-2024-221].
CR Chen X, 2017, Zhonghua Yi Xue Za Zhi, V97, P308, DOI 10.3760/cma.j.issn.0376-2491.2017.04.015
   Lima Sérgio José de, 2009, Rev. bras. ortop., V44, P40, DOI 10.1016/S2255-4971(15)30047-1
   Debrah Samuel, 2020, Ghana Med J, V54, P197, DOI [10.4314/gmj.v54i3.11, 10.4314/gmj.v54i3.11]
   Herbert HK, 2011, INFECT DIS CLIN N AM, V25, P653, DOI 10.1016/j.idc.2011.06.004
   Kim P, 2019, PRS-GLOB OPEN, V7, DOI 10.1097/GOX.0000000000002129
   Lv ZM, 2019, MEDICINE, V98, DOI 10.1097/MD.0000000000017726
   Mahajan RK, 2019, INDIAN J PLAST SURG, V52, P45, DOI 10.1055/s-0039-1688097
   Mao SD, 2023, INT J BIOPRINTING, V9, P49, DOI 10.18063/ijb.v9i2.653
   Murray RC, 2011, MICROSURG, V31, P104, DOI 10.1002/micr.20833
   Palmieri TL, 2023, J BURN CARE RES, V44, pS65, DOI 10.1093/jbcr/irac102
   Philandrianos C, 2012, BURNS, V38, P820, DOI 10.1016/j.burns.2012.02.008
   Scalise A, 2016, INT WOUND J, V13, P1260, DOI 10.1111/iwj.12492
   Shang F, 2021, INT WOUND J, V18, P24, DOI 10.1111/iwj.13518
   Sharma N, 2023, CUREUS J MED SCIENCE, V15, DOI 10.7759/cureus.39390
   Sorg H, 2017, EUR SURG RES, V58, P81, DOI 10.1159/000454919
   Tchero H, 2017, EUROPEAN TISSUE REPA, V25, P691, DOI [10.1111/wrr.12554, DOI 10.1111/WRR.12554]
   Thakkar Mehul, 2021, Eplasty, V21, pe2
   Wang W, 2023, WORLD J CLIN CASES, V11, DOI 10.12998/wjcc.v11.i33.8003
   Wei ZY, 2023, J CRANIOFAC SURG, V34, P759, DOI 10.1097/SCS.0000000000009118
   Wu L, 2023, Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi, V39, P959, DOI 10.3760/cma.j.cn501225-20230428-00145
   Wu YZ, 2023, INT WOUND J, V20, P2113, DOI 10.1111/iwj.14086
   Yan HD, 2010, J INVEST SURG, V23, P249, DOI 10.3109/08941931003615529
   Yuan Y, 2023, FRONT SURG, V10, DOI 10.3389/fsurg.2023.1304333
   Zhu J, 2024, J WOUND CARE, V33
   Zou SY, 2024, J HAND SURG-AM, V49, p385e1, DOI 10.1016/j.jhsa.2023.12.003
NR 25
TC 0
Z9 0
U1 1
U2 2
PU SPRINGER INDIA
PI NEW DELHI
PA 7TH FLOOR, VIJAYA BUILDING, 17, BARAKHAMBA ROAD, NEW DELHI, 110 001,
   INDIA
SN 0972-2068
EI 0973-9793
J9 INDIAN J SURG
JI Indian J. Surg
PD APR
PY 2026
VL 88
IS 2
BP 328
EP 334
DI 10.1007/s12262-025-04384-y
EA JUL 2025
PG 7
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA GQ9SL
UT WOS:001522674500001
DA 2026-07-24
ER

PT J
AU Schessel, ES
   Ger, R
AF Schessel, Eli S.
   Ger, Ralph
TI Closure of Difficult Wounds by External Tissue Expansion
SO WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
LA English
DT Review
ID COMPLICATIONS; MANAGEMENT
AB The open nonhealing wound is a persistent challenge to physicians. Infections, foreign bodies, osteomyelitis, and skin coverage of repaired structures remain problems. As the body ages, the elderly are prone to the development of pressure sores and foot ulcers, particularly patients with diabetes. Many elderly patients will have comorbid conditions making closure of these wounds difficult. The authors have more than 100 combined years of experience treating wounds. Throughout their long careers the authors have treated numerous wounds with various types of methods. Antibiotics were introduced during World War II; specially developed colloidal dressings, growth factors, and negative pressure wound therapy were introduced to expedite epithelial coverage of wounds. The plastic surgery field was developed through the introduction of flaps to close wounds. In the last 12 years, we have closed most wounds with an external tissue expansion device usually in 1 to 2 weeks. A quickly closed wound improves the quality of life for the patient and reduces the cost to the healthcare system.
C1 [Schessel, Eli S.] Flushing Hosp & Med Ctr, New York, NY USA.
RP Schessel, ES (通讯作者)，108-33 70th Rd, Forest Hills, NY 11375 USA.
EM woodwest3@aol.com
CR ANTONYSHYN O, 1988, BRIT J PLAST SURG, V41, P239, DOI 10.1016/0007-1226(88)90107-5
   AUSTAD ED, 1986, PLAST RECONSTR SURG, V78, P63, DOI 10.1097/00006534-198607000-00009
   De Filippo RE, 2002, PLAST RECONSTR SURG, V109, P2450, DOI 10.1097/00006534-200206000-00043
   ELLENBERG M, 1970, DIABETES MELLITUS TH, P890
   Ger R, 2005, J AM COLL SURGEONS, V201, P898, DOI 10.1016/j.jamcollsurg.2005.07.015
   Kynes P M, 1986, J Enterostomal Ther, V13, P42
   MANDERS EK, 1988, PLAST RECONSTR SURG, V81, P208, DOI 10.1097/00006534-198802000-00012
   MASSER MR, 1990, BRIT J PLAST SURG, V43, P344, DOI 10.1016/0007-1226(90)90085-E
   Schessel E S, 2000, J Foot Ankle Surg, V39, P321
   Schessel ES, 2002, AM J SURG, V184, P263, DOI 10.1016/S0002-9610(02)00935-2
   Schessel ES, 2001, BRIT J PLAST SURG, V54, P439, DOI 10.1054/bjps.2001.3605
NR 11
TC 4
Z9 4
U1 0
U2 1
PU H M P COMMUNICATIONS
PI MALVERN
PA 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA
SN 1044-7946
J9 WOUNDS
JI Wounds-Compend. Clin. Res. Pract.
PD JUN
PY 2010
VL 22
IS 6
BP 151
EP 157
PG 7
WC Dermatology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology; Surgery
GA 613DU
UT WOS:000278958900005
PM 25901465
DA 2026-07-24
ER

PT J
AU Xia, YF
   Wu, P
   Chen, YS
   Chen, ZY
AF Xia, Yinfeng
   Wu, Ping
   Chen, Yongsong
   Chen, Zhiyong
TI Current research progress on the use of traditional Chinese medicine in
   the treatment of diabetic foot ulcers
SO FRONTIERS IN ENDOCRINOLOGY
LA English
DT Review
DE diabetic foot ulcers; traditional Chinese medicine; wound; diabetes
   mellitus; wound healing
ID HYPOXIA-INDUCIBLE FACTOR; DOUBLE-BLIND; MECHANISMS; THERAPY
AB Diabetic foot ulcers represent a significant complication of diabetes mellitus, presenting substantial challenges due to their intricate pathogenesis, which encompasses neuropathy, vasculopathy, chronic inflammation, and biofilm-associated infections. Despite considerable advancements in Western medical interventions, including surgical debridement, skin grafting, negative pressure wound therapy, and innovative dressings, these ulcers remain a leading cause of amputation and contribute to a substantial socioeconomic burden. Traditional Chinese medicine (TCM) has emerged as a promising adjunctive therapy, offering multi-targeted mechanisms that address oxidative stress, chronic inflammation, angiogenesis, and microbial resistance associated with diabetic foot ulcers. This review aims to examine contemporary studies on the application of TCM in the treatment of diabetic foot ulcers, evaluating its efficacy and elucidating its mechanisms of action, thereby providing a reference for clinical treatment decisions and guiding future research directions.
C1 [Xia, Yinfeng; Wu, Ping; Chen, Yongsong; Chen, Zhiyong] Chongqing Univ, Fuling Hosp, Dept Burns Plast Surg & Cosmetol, Chongqing, Peoples R China.
C3 Chongqing University
RP Chen, ZY (通讯作者)，Chongqing Univ, Fuling Hosp, Dept Burns Plast Surg & Cosmetol, Chongqing, Peoples R China.
EM czy1002008@cqu.edu.cn
FU Science-Health Joint Medical Scientific Research Project of
   Chongqing10.13039/100017501
FX The authors would like to thank all those who contributed to this
   article.
CR Abdoli A, 2022, DIABETES METAB SYND, V16, DOI 10.1016/j.dsx.2022.102678
   Afonso AC, 2021, INT J MOL SCI, V22, DOI 10.3390/ijms22158278
   Alavi A, 2014, J AM ACAD DERMATOL, V70, DOI 10.1016/j.jaad.2013.07.048
   Alavi A, 2014, J AM ACAD DERMATOL, V70, DOI 10.1016/j.jaad.2013.06.055
   Armstrong DG, 2023, JAMA-J AM MED ASSOC, V330, P62, DOI 10.1001/jama.2023.10578
   Bandyk DF, 2018, SEMIN VASC SURG, V31, P43, DOI 10.1053/j.semvascsurg.2019.02.001
   Borgia F, 2023, J CLIN MED, V12, DOI 10.3390/jcm12083043
   Bus SA, 2024, DIABETES-METAB RES, V40, DOI 10.1002/dmrr.3651
   Chang M, 2021, ACCOUNTS CHEM RES, V54, P1080, DOI 10.1021/acs.accounts.0c00864
   Chen LY, 2021, BIOMEDICINES, V9, DOI 10.3390/biomedicines9070761
   Chen LY, 2020, ANTIOXIDANTS-BASEL, V9, DOI 10.3390/antiox9111122
   Chen M, 2010, J ALTERN COMPLEM MED, V16, P889, DOI 10.1089/acm.2009.0470
   Deng LL, 2021, OXID MED CELL LONGEV, V2021, DOI 10.1155/2021/8852759
   Dodson M, 2019, ANNU REV PHARMACOL, V59, P555, DOI 10.1146/annurev-pharmtox-010818-021856
   Duscher D, 2015, PLAST RECONSTR SURG, V136, P1004, DOI 10.1097/PRS.0000000000001699
   Falanga V, 2005, LANCET, V366, P1736, DOI 10.1016/S0140-6736(05)67700-8
   Fan WJ, 2020, BMJ OPEN, V10, DOI 10.1136/bmjopen-2020-039898
   Gordon Katherine A, 2012, Skinmed, V10, P24
   Hall CW, 2017, FEMS MICROBIOL REV, V41, P276, DOI [10.1093/femsre/f, 10.1093/femsre/fux010]
   Hong WX, 2014, ADV WOUND CARE, V3, P390, DOI 10.1089/wound.2013.0520
   Hoxhaj G, 2020, NAT REV CANCER, V20, P74, DOI 10.1038/s41568-019-0216-7
   Huang K, 2025, BURNS TRAUMA, V13, DOI 10.1093/burnst/tkae052
   Huang YW, 2019, FASEB J, V33, P953, DOI 10.1096/fj.201800337R
   Huang YY, 2021, JAMA NETW OPEN, V4, DOI 10.1001/jamanetworkopen.2021.22607
   Huseini HF, 2024, INT J LOW EXTR WOUND, V23, P238, DOI 10.1177/15347346211048371
   Irani Parichehr Sabaghzadeh, 2024, Current Drug Discovery Technologies, V21, DOI [10.2174/1570163820666230904150945, 10.2174/1570163820666230904150945]
   Jere SW, 2019, CYTOKINE GROWTH F R, V50, P52, DOI 10.1016/j.cytogfr.2019.03.001
   Jetten N, 2014, ANGIOGENESIS, V17, P109, DOI 10.1007/s10456-013-9381-6
   Jiang PN, 2023, FRONT ENDOCRINOL, V14, DOI 10.3389/fendo.2023.1221705
   Ko CH, 2014, J DIABETES, V6, P323, DOI 10.1111/1753-0407.12117
   Kulwas A, 2017, ADV MED SCI-POLAND, V62, P87, DOI 10.1016/j.advms.2016.07.007
   Kulwas A, 2015, J DIABETES COMPLICAT, V29, P686, DOI 10.1016/j.jdiacomp.2015.03.013
   Kuo YS, 2012, EVID-BASED COMPL ALT, V2012, DOI 10.1155/2012/418679
   Larouche J, 2018, ADV WOUND CARE, V7, P209, DOI 10.1089/wound.2017.0761
   Lawrence T, 2009, CSH PERSPECT BIOL, V1, DOI 10.1101/cshperspect.a001651
   Lee MKS, 2020, CLIN SCI, V134, P1399, DOI 10.1042/CS20200240
   Leu WJ, 2019, FRONT PHARMACOL, V10, DOI 10.3389/fphar.2019.00573
   Li GD, 2022, EXP MOL MED, V54, P988, DOI 10.1038/s12276-022-00804-1
   Li SF, 2011, J ETHNOPHARMACOL, V133, P543, DOI 10.1016/j.jep.2010.10.040
   Li WB, 2018, EXCLI J, V17, P399, DOI 10.17179/excli2018-1036
   Li Xin, 2019, Zhongguo Zhong Yao Za Zhi, V44, P2110, DOI 10.19540/j.cnki.cjcmm.20190328.201
   Lipsky BA, 2013, J AM PODIAT MED ASSN, V103, P2, DOI 10.7547/1030002
   Liu Bo, 2016, Zhongguo Zhong Yao Za Zhi, V41, P118, DOI [10.4268/cjcmm20160123, 10.4268/cjcmm20160123]
   Liu FS, 2022, WORLD J DIABETES, V13, P851, DOI 10.4239/wjd.v13.i10.851
   Liu M, 2019, INT J IMMUNOPATH PH, V33, DOI 10.1177/2058738419866379
   Liu TT, 2023, ACTA PHARMACOL SIN, V44, P2492, DOI 10.1038/s41401-023-01127-1
   Liu YL, 2020, MED SCI MONITOR, V26, DOI 10.12659/MSM.923424
   Louiselle AE, 2021, TRANSL RES, V236, P109, DOI 10.1016/j.trsl.2021.05.006
   Ma YG, 2021, CELLS-BASEL, V10, DOI 10.3390/cells10071676
   Mauricio D, 2016, J DIABETES RES, V2016, DOI 10.1155/2016/5691305
   Mohajeri G, 2014, J RES MED SCI, V19, P520
   Mohsin F, 2024, INT IMMUNOPHARMACOL, V139, DOI 10.1016/j.intimp.2024.112713
   Mokhtari M, 2021, PHYTOTHER RES, V35, P2099, DOI 10.1002/ptr.6957
   Morita Y, 2016, FRONT MICROBIOL, V7, DOI 10.3389/fmicb.2016.01223
   Moura J, 2017, CELL MOL IMMUNOL, V14, P758, DOI 10.1038/cmi.2015.116
   Najafian Younes, 2019, Curr Drug Discov Technol, V16, P223, DOI [10.2174/1570163815666180115093007, 10.2174/1570163815666180115093007]
   Oh S, 2020, MAR DRUGS, V18, DOI 10.3390/md18120648
   Paocharoen Veeraya, 2010, J Med Assoc Thai, V93 Suppl 7, pS166
   Pasupuleti VR, 2020, OXID MED CELL LONGEV, V2020, DOI 10.1155/2020/8878172
   Percival SL, 2012, WOUND REPAIR REGEN, V20, P647, DOI 10.1111/j.1524-475X.2012.00836.x
   Pulkkinen HH, 2021, ANGIOGENESIS, V24, P129, DOI 10.1007/s10456-020-09748-4
   Rai V, 2022, CELLS-BASEL, V11, DOI 10.3390/cells11152287
   Rathnayake A, 2020, WORLD J DIABETES, V11, P391, DOI 10.4239/wjd.v11.i9.391
   Reardon R, 2020, AUST J GEN PRACT, V49, P250, DOI 10.31128/AJGP-11-19-5161
   Rehak L, 2022, J CLIN MED, V11, DOI 10.3390/jcm11030889
   Ren J, 2020, BIOMED PHARMACOTHER, V129, DOI 10.1016/j.biopha.2020.110475
   Ren J, 2019, LIFE SCI, V233, DOI 10.1016/j.lfs.2019.116728
   Romero-Cerecero O, 2015, PLANTA MED, V81, P272, DOI 10.1055/s-0034-1396315
   Schaper NC, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3266
   Semis HS, 2022, J BIOCHEM MOL TOXIC, V36, DOI 10.1002/jbt.23121
   Seraphim PM, 2020, LIFE SCI, V254, DOI 10.1016/j.lfs.2020.117813
   Shu X, 2018, ENDOCR J, V65, P403, DOI 10.1507/endocrj.EJ17-0424
   Singh N, 2005, JAMA-J AM MED ASSOC, V293, P217, DOI 10.1001/jama.293.2.217
   Smigiel KS, 2018, CURR RHEUMATOL REP, V20, DOI 10.1007/s11926-018-0725-5
   Soleimani Z, 2017, J DIABETES COMPLICAT, V31, P1394, DOI 10.1016/j.jdiacomp.2017.06.010
   Sun H, 2022, DIABETES RES CLIN PR, V183, DOI 10.1016/j.diabres.2021.109119
   Sun HM, 2020, CURR DRUG TARGETS, V21, P1264, DOI 10.2174/1389450121666200623131200
   Sun XL, 2021, DRUG DEVELOP RES, V82, P404, DOI 10.1002/ddr.21763
   Sun X, 2024, HELIYON, V10, DOI [10.1016/j.heliyon.2024.e39716, 10.1016/j.heliyon.2024.e39716]
   Sun Y, 2019, EVID-BASED COMPL ALT, V2019, DOI 10.1155/2019/7621929
   Tan LZ, 2018, EVID-BASED COMPL ALT, V2018, DOI 10.1155/2018/4730896
   Wan LQ, 2022, INT J BIOL SCI, V18, P809, DOI 10.7150/ijbs.63219
   Wan XP, 2021, EVID-BASED COMPL ALT, V2021, DOI 10.1155/2021/1334255
   Wang TF, 2017, FRONT IMMUNOL, V8, DOI 10.3389/fimmu.2017.00433
   Li WH, 2021, DIABETES RES CLIN PR, V176, DOI 10.1016/j.diabres.2021.108862
   Wu LH, 2016, MOL NEUROBIOL, V53, P1080, DOI 10.1007/s12035-014-9042-9
   Xie XL, 2019, J INT MED RES, V47, P4656, DOI 10.1177/0300060519858033
   Xiong WJ, 2020, ANDROLOGY-US, V8, P1875, DOI 10.1111/andr.12844
   Xue B, 2017, J NAT MED-TOKYO, V71, P472, DOI 10.1007/s11418-016-1067-0
   Xue X, 2019, INT J MOL SCI, V20, DOI 10.3390/ijms20236097
   Yue SJ, 2017, FRONT PHARMACOL, V8, DOI 10.3389/fphar.2017.00694
   Zhang BJ, 2018, EVID-BASED COMPL ALT, V2018, DOI 10.1155/2018/2789847
   Zhang E, 2016, J PHARMACOL EXP THER, V356, P324, DOI 10.1124/jpet.115.229369
   Zhang H, 2018, FRONT PHARMACOL, V9, DOI 10.3389/fphar.2018.01114
   Zhang ZC, 2021, TRENDS FOOD SCI TECH, V114, P11, DOI 10.1016/j.tifs.2021.05.023
   Zhao BJ, 2021, EUR J PHARMACOL, V912, DOI 10.1016/j.ejphar.2021.174607
   Zhou SQ, 2020, CELL MOL IMMUNOL, V17, P335, DOI 10.1038/s41423-020-0399-6
   Zhu YB, 2021, EVID-BASED COMPL ALT, V2021, DOI 10.1155/2021/6079305
NR 98
TC 3
Z9 4
U1 12
U2 22
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 1664-2392
J9 FRONT ENDOCRINOL
JI Front. Endocrinol.
PD AUG 22
PY 2025
VL 16
AR 1637128
DI 10.3389/fendo.2025.1637128
PG 8
WC Endocrinology & Metabolism
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Endocrinology & Metabolism
GA 6WY5W
UT WOS:001563992500001
PM 40917350
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Baptista, AM
   De Camargo, AFD
   Caiero, MT
   Torres, JSD
   Narciso, JH
   Silva, MRD
AF Baptista, Andre Mathias
   De Camargo, Andre Ferrari De Franca
   Caiero, Marcelo Tadeu
   Torres Filho, Jose Saint Clair De Sousa
   Narciso, Jorge Henrique
   Silva, Marcela Rocha Dias
TI ROLE OF INCISIONAL VACUUM THERAPY IN ENDOPROSTHETIC BONE RECONSTRUCTION
   SURGERY
SO ACTA ORTOPEDICA BRASILEIRA
LA English
DT Article
DE Negative Pressure Wound Therapy; Prostheses and Implants; Osteosarcoma
ID PRESSURE WOUND THERAPY; 1ST REVISION; INFECTIONS
AB Reconstructive surgery with endoprostheses is the chosen method for treating bone malignancies. Postoperative infections are frequent complications, and their treatment involves prolonged hospital stays and antibiotic therapy. Among the advancements aimed at reducing the rate of postoperative infection, the use of incisional negative pressure therapy (iNPT) has shown promising results, with no reports in the literature regarding its use in patients with such conditions. Objective: To evaluate the effectiveness of iNPT in reducing postoperative complications in surgeries for resection of bone tumors associated with modular endoprosthesis reconstruction. Methods: Retrospective case series of 16 patients diagnosed with osteosarcoma, who underwent resection and reconstruction with endoprosthesis associated with iNPT during the postoperative period. Follow-up was performed for a period of six months, and the evaluated outcomes were the incidence of postoperative infection and complications of the surgical wound. Results: The use of iNPT for a postoperative period of seven days resulted in only three (18.7%) bone malignancies.
C1 [Baptista, Andre Mathias; De Camargo, Andre Ferrari De Franca; Caiero, Marcelo Tadeu; Torres Filho, Jose Saint Clair De Sousa; Narciso, Jorge Henrique; Silva, Marcela Rocha Dias] Univ Sao Paulo, Hosp Clin, Fac Med, Inst Ortopedia & Traumatol IOT HCFMUSP,Grp Oncol O, Sao Paulo, SP, Brazil.
   [Baptista, Andre Mathias] Rua Dr Ovidio Pires Campos 333, BR-05403010 Sao Paulo, SP, Brazil.
C3 Universidade de Sao Paulo
RP Baptista, AM (通讯作者)，Rua Dr Ovidio Pires Campos 333, BR-05403010 Sao Paulo, SP, Brazil.
EM andre.ferrari@fm.usp.br
RI Baptista, Ane Mathias/AAD-6498-2019
OI Baptista, Ane Mathias/0000-0002-0830-4602; Caiero,
   Marcelo/0000-0003-4891-0276; Narciso, Jorge
   Henrique/0000-0003-0548-836X; Tôrres Filho, José Saint Clair de
   Sousa/0000-0001-9942-6818; Camargo, André Ferrari de
   França/0000-0003-0317-3807
CR Broex ECJ, 2009, J HOSP INFECT, V72, P193, DOI 10.1016/j.jhin.2009.03.020
   Cooper HJ, 2018, INJURY, V49, P386, DOI 10.1016/j.injury.2017.11.010
   Gustafsson R, 2007, EUROPEAN WOUND MANAG
   Hammond C, 2008, EVIDENCE REV VACUUM, P1
   Hardes J, 2006, ARCH ORTHOP TRAUM SU, V126, P289, DOI 10.1007/s00402-005-0009-1
   Hyldig N, 2016, BJS-BRIT J SURG, V103, P477, DOI 10.1002/bjs.10084
   Jeys LM, 2005, J BONE JOINT SURG AM, V87A, P842, DOI 10.2106/JBJS.C.01222
   Magill SS, 2014, NEW ENGL J MED, V370, P1198, DOI 10.1056/NEJMoa1306801
   Nam D, 2018, J AM ACAD ORTHOP SUR, V26, P295, DOI 10.5435/JAAOS-D-17-00054
   Nherera LM, 2017, WOUND REPAIR REGEN, V25, P474, DOI 10.1111/wrr.12530
   Paulitsch-Fuchs AH, 2021, J FUNCT BIOMATER, V12, DOI 10.3390/jfb12020036
   Shepard J, 2013, JAMA SURG, V148, P907, DOI 10.1001/jamasurg.2013.2246
   Theil C, 2019, CLIN ORTHOP RELAT R, V477, P2705, DOI 10.1097/CORR.0000000000000955
   Theil C, 2021, CANCERS, V13, DOI 10.3390/cancers13112510
   Thornley P, 2019, CLIN ORTHOP RELAT R, V477, P894, DOI 10.1097/CORR.0000000000000630
   Weed T, 2004, ANN PLAS SURG, V52, P276, DOI 10.1097/01.sap.0000111861.75927.4d
NR 16
TC 0
Z9 0
U1 0
U2 3
PU ATHA COMUNICACAO & EDITORA
PI SAO PAULO
PA RUA MACHADO BITTENCOURT, 190-40 ANDAR, CONJ 410, SAO PAULO, Sao Paulo,
   BRAZIL
SN 1413-7852
EI 1809-4406
J9 ACTA ORTOP BRAS
JI Acta Ortop. Bras.
PY 2023
VL 31
IS 4
AR e260330
DI 10.1590/1413-785220233104e260330
PG 3
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA P4FS3
UT WOS:001050225900005
PM 37547234
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Aleksandrowicz, H
   Owczarczyk-Saczonek, A
   Placek, W
AF Aleksandrowicz, Hubert
   Owczarczyk-Saczonek, Agnieszka
   Placek, Waldemar
TI Venous Leg Ulcers: Advanced Therapies and New Technologies
SO BIOMEDICINES
LA English
DT Review
DE venous leg ulcers; advanced therapies; new technologies; wound
   treatment; experimental dermatology
ID ALPHA; WOUNDS
AB The prevalence of venous leg ulcers (VLUs) differs between 1.5% and 3% in the general population. The challenge in treating VLUs is common recurrence. Moreover, VLUs can be resistant to healing, despite appropriate treatment. In these cases, advanced wound therapies should be considered. The number of new technologies, applied in VLUs treatment, has increased in the last years. These therapies include biophysical interventions such as ultrasound therapy, electrical stimulations, electromagnetic therapy, or phototherapy. Furthermore, stem cell therapies, biologic skin equivalents, platelet-rich plasma therapy, oxygen therapies, anti-TNF therapy, or negative pressure wound therapy are advanced venous ulcer therapeutic methods that may support the standard of care. Medical devices, such as a muscle pump activator, or intermittent pneumatic compression device, may be especially useful for specific subgroups of patients suffering from VLUs. Some of the above-mentioned technologies require broader evidence of clinical efficacy and are still considered experimental therapies in dermatology.
C1 [Aleksandrowicz, Hubert; Owczarczyk-Saczonek, Agnieszka; Placek, Waldemar] Univ Warmia & Mazury, Dept & Clin Dermatol, Sexually Transmitted Dis & Clin Immunol, Al Wojska Polskiego 30, PL-10959 Olsztyn, Poland.
C3 University of Warmia & Mazury
RP Aleksandrowicz, H (通讯作者)，Univ Warmia & Mazury, Dept & Clin Dermatol, Sexually Transmitted Dis & Clin Immunol, Al Wojska Polskiego 30, PL-10959 Olsztyn, Poland.
EM hubert.aleksandrowicz@gmail.com; agnieszka.owczarczyk@uwm.edu.pl;
   w.placek@wp.pl
RI Owczarczyk-Saczonek, Agnieszka/AAN-5260-2020
OI Aleksandrowicz, Hubert/0000-0001-8807-2567
CR Alkhateep Y, 2018, EGYPT J SURG, V37, P196, DOI 10.4103/ejs.ejs_147_17
   Alvarez Oscar M, 2020, Eplasty, V20, pe6
   Andrade Sabrina Meireles de, 2016, Rev Gaucha Enferm, V37, pe59257, DOI 10.1590/1983-1447.2016.02.59257
   Apovian Caroline M., 2016, AMERICAN JOURNAL OF MANAGED CARE, V22
   Aziz Z, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD002933.pub6
   Bavaresco T, 2018, TRIALS, V19, DOI 10.1186/s13063-018-2729-x
   Bazalinski D, 2019, J CLIN MED, V8, DOI 10.3390/jcm8111845
   Beheshti A, 2014, ADV CLIN EXP MED, V23, P969, DOI 10.17219/acem/37353
   Cereceres S, 2019, APL BIOENG, V3, DOI 10.1063/1.5088801
   Charles CA, 2009, J AM ACAD DERMATOL, V60, P951, DOI 10.1016/j.jaad.2008.09.012
   Chooi YC, 2019, METABOLISM, V92, P6, DOI 10.1016/j.metabol.2018.09.005
   Coalson E, 2019, GENES DIS, V6, P342, DOI 10.1016/j.gendis.2019.09.008
   Cowin AJ, 2006, WOUND REPAIR REGEN, V14, P421, DOI 10.1111/j.1743-6109.2006.00141.x
   Cullum N, 2017, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001180.pub4
   Cuomo Roberto, 2017, Acta Biomed, V88, P297, DOI 10.23750/abm.v88i3.5737
   Dehkordi AN, 2019, STEM CELL RES THER, V10, DOI 10.1186/s13287-019-1212-2
   Dumville JC, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011354.pub2
   Elio C, 2020, ACTA DERMATOVEN ALP, V29, P109, DOI 10.15570/actaapa.2020.24
   Evans R., 2019, Foundations of Best Practice for Skin and Wound Management
   Fan WJ, 2020, BMJ OPEN, V10, DOI 10.1136/bmjopen-2020-039898
   Fox JD, 2016, INT WOUND J, V13, P963, DOI 10.1111/iwj.12497
   Hadian Y, 2019, MEDIAT INFLAMM, V2019, DOI 10.1155/2019/1297675
   Harries RL, 2016, INT WOUND J, V13, P8, DOI 10.1111/iwj.12662
   Harris C, 2017, INT WOUND J, V14, P1189, DOI 10.1111/iwj.12784
   Holm JS, 2018, STEM CELL RES THER, V9, DOI 10.1186/s13287-018-0887-0
   Huber SC, 2021, REGEN THER, V18, P51, DOI 10.1016/j.reth.2021.03.005
   Illescas-Montes R, 2018, COCHRANE DB SYST REV, V2018, pCD013061, DOI [DOI 10.1002/14651858.CD013061, 10.1002/14651858.CD013061]
   Martinez-Zapata MJ, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD006899.pub3
   Kranke P, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004123.pub4
   Kucharzewski M, 2014, BIOMED RES INT-UK, V2014, DOI 10.1155/2014/297230
   Matias MAT, 2011, J INFLAMM-LOND, V8, DOI 10.1186/1476-9255-8-39
   Megahed M.A., 2019, MENOUFIA MED J, V32, P723
   Mutluoglu Mesut, 2013, J Am Coll Clin Wound Spec, V5, P61, DOI 10.1016/j.jccw.2014.12.003
   Neumann HAM, 2016, J EUR ACAD DERMATOL, V30, P1843, DOI 10.1111/jdv.13848
   Raffetto JD, 2021, J CLIN MED, V10, DOI 10.3390/jcm10010029
   Raghuram AC, 2020, WORLD J STEM CELLS, V12, P659, DOI 10.4252/wjsc.v12.i7.659
   Rajendran SB, 2021, J FUNCT BIOMATER, V12, DOI 10.3390/jfb12020040
   Ren SY, 2020, WORLD J CLIN CASES, V8, DOI 10.12998/wjcc.v8.i21.5070
   Romanelli M, 2017, DRUG DES DEV THER, V11, P3551, DOI 10.2147/DDDT.S142580
   Sawad AB, 2020, J COMP EFFECT RES, V9, P907, DOI 10.2217/cer-2020-0076
   Sugerman HJ, 2001, ANN SURG, V234, P41, DOI 10.1097/00000658-200107000-00007
   Sultan S., TOPICAL WOUND OXYGEN
   Suthar M, 2017, J BIOMED SCI, V24, DOI 10.1186/s12929-017-0324-1
   Thistlethwaite KR, 2018, WOUND REPAIR REGEN, V26, P324, DOI 10.1111/wrr.12657
   Verkey M., 2013, WOUNDS UK, V9, P60
   Wallace HJ, 1998, J INVEST DERMATOL, V110, P292, DOI 10.1046/j.1523-1747.1998.00113.x
   Wilson Joyce A, 2004, Adv Skin Wound Care, V17, P426, DOI 10.1097/00129334-200410000-00013
NR 47
TC 33
Z9 42
U1 3
U2 30
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2227-9059
J9 BIOMEDICINES
JI Biomedicines
PD NOV
PY 2021
VL 9
IS 11
AR 1569
DI 10.3390/biomedicines9111569
PG 12
WC Biochemistry & Molecular Biology; Medicine, Research & Experimental;
   Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biochemistry & Molecular Biology; Research & Experimental Medicine;
   Pharmacology & Pharmacy
GA XK8FN
UT WOS:000727694400001
PM 34829797
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Pandey, G
   Kolipaka, T
   Srinivasarao, DA
   Abraham, N
   Jain, A
   Srivastava, S
AF Pandey, Giriraj
   Kolipaka, Tejaswini
   Srinivasarao, Dadi A.
   Abraham, Noella
   Jain, Akshita
   Srivastava, Saurabh
TI Navigating the complexities of diabetic foot ulcers: From
   pathophysiology to advanced treatment strategies
SO JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
LA English
DT Review
DE Diabetes; Diabetic foot ulcer; Wound dressing; Nanofiber; Growth factors
ID HYPERBARIC-OXYGEN THERAPY; EPIDERMAL-GROWTH-FACTOR; PRESSURE WOUND
   THERAPY; PLATELET-RICH PLASMA; MATRIX METALLOPROTEINASES; DOUBLE-BLIND;
   SKIN-GRAFT; LEG ULCERS; MANAGEMENT; DRESSINGS
AB Diabetic foot ulcers (DFUs) are the most prevalent and serious complication among diabetic patients, causing substantial health and economic burden due to low rate of healing and high recurrence. Current therapies for DFUs include surgical debridement, wound dressings, pressure offloading, revascularization, hyperbaric oxygen therapy, low-level laser therapy, and negative pressure wound therapy. In this review, we discussed conventional and emerging therapies using hydrogel and nanofiber-based treatments, stem cell approaches, 3D bioprinting, growth factors, matrix metalloproteinase (MMP) modulators, and bioengineered skin substitutes, which showed improved healing and reduced the risk of amputation. The current article attempts to give an in-depth overview of DFU management by examining established and innovative techniques. Further, this review emphasizes the necessity of multidisciplinary approaches to enhance patient compliance and lessen the burden of devastating pathological conditions.
C1 [Pandey, Giriraj; Kolipaka, Tejaswini; Srinivasarao, Dadi A.; Abraham, Noella; Jain, Akshita; Srivastava, Saurabh] Natl Inst Pharmaceut Educ & Res NIPER, Dept Pharmaceut, Pharmaceut Innovat & Translat Res Lab PITRL, Hyderabad, India.
C3 National Institute of Pharmaceutical Education & Research, S.A.S. Nagar
   (Mohali); National Institute of Pharmaceutical Education & Research,
   Hyderabad
RP Srivastava, S (通讯作者)，Natl Inst Pharmaceut Educ & Res NIPER, Dept Pharmaceut, Pharmaceut Innovat & Translat Res Lab PITRL, Hyderabad, India.
EM saurabh@niperhyd.ac.in
RI Srinivasarao, Dadi/K-7507-2018; Srivastava, Saurabh/GWD-0786-2022
OI Srivastava, Saurabh/0000-0003-0723-4363
FU Department of Pharmaceuticals (DoP) , Ministry of Chemicals and
   Fertilizers, Govt. of India
FX The authors would like to acknowledge the research funding support by
   the Department of Pharmaceuticals (DoP) , Ministry of Chemicals and
   Fertilizers, Govt. of India to "Pharmaceutical Innovation and
   Translational Research Lab" (PITRL) , Department of Pharmaceutics,
   National Institute of Pharmaceutical Education and Research (NIPER)
   Hyderabad, INDIA.
CR Abraham N, 2025, INT J BIOL MACROMOL, V306, DOI 10.1016/j.ijbiomac.2025.141352
   Abraham N, 2024, LIFE SCI, V343, DOI 10.1016/j.lfs.2024.122545
   Abu-Qamar MZ, 2021, INT J NURS STUD, V114, DOI 10.1016/j.ijnurstu.2020.103822
   AHRQ, 2019, Skin Substitutes for Treating Chronic Wounds
   Alamdari NM, 2021, DIABETES METAB SYND, V15, P621, DOI 10.1016/j.dsx.2021.03.005
   Alexiadou Kleopatra, 2012, Diabetes Ther, V3, P4, DOI 10.1007/s13300-012-0004-9
   Alzahrani D.A., INT J NANOMEDICINE
   Amin AH, 2010, LAB INVEST, V90, P985, DOI 10.1038/labinvest.2010.86
   Amin KN, 2020, MICROVASC RES, V127, DOI 10.1016/j.mvr.2019.103924
   [Anonymous], 2015, Diabetic foot problems: prevention and management
   Ardelean Andrei, 2024, Med Pharm Rep, V97, P419, DOI [10.15386/mpr-2818, 10.15386/mpr-2818]
   Armstrong David G, 2004, Int Wound J, V1, P123, DOI 10.1111/j.1742-4801.2004.00035.x
   Armstrong DG, 2017, NEW ENGL J MED, V376, P2367, DOI 10.1056/NEJMra1615439
   Ashcroft GS, 1997, NAT MED, V3, P1209, DOI 10.1038/nm1197-1209
   Avitabile S, 2015, J INVEST DERMATOL, V135, P2862, DOI 10.1038/jid.2015.278
   Azari Z, 2022, WOUND REPAIR REGEN, V30, P421, DOI 10.1111/wrr.13033
   Balin SO, 2019, INT WOUND J, V16, P659, DOI 10.1111/iwj.13075
   Baltazar T, 2020, TISSUE ENG PT A, V26, P227, DOI [10.1089/ten.tea.2019.0201, 10.1089/ten.TEA.2019.0201]
   Baltzis D, 2014, ADV THER, V31, P817, DOI 10.1007/s12325-014-0140-x
   Barrientos S, 2014, WOUND REPAIR REGEN, V22, P569, DOI 10.1111/wrr.12205
   Bao Philip, 2009, J Surg Res, V153, P347, DOI 10.1016/j.jss.2008.04.023
   Acosta JB, 2008, INT WOUND J, V5, P530, DOI 10.1111/j.1742-481X.2008.00457.x
   Berlanga-Acosta J, 2011, INT WOUND J, V8, P612, DOI 10.1111/j.1742-481X.2011.00840.x
   Bhattacharya S, 2015, MOL MED, V21, P847, DOI 10.2119/molmed.2014.00186
   Biondo M, 2024, HELIYON, V10, DOI 10.1016/j.heliyon.2024.e36707
   Blazar BR, 1997, IMMUNOL REV, V157, P79, DOI 10.1111/j.1600-065X.1997.tb00976.x
   Bordbar-Khiabani A, 2022, INT J MOL SCI, V23, DOI 10.3390/ijms23073665
   Borys S, 2019, EUR J CLIN INVEST, V49, DOI 10.1111/eci.13067
   Boucher J, 2014, CSH PERSPECT BIOL, V6, DOI 10.1101/cshperspect.a009191
   Brás T, 2020, INT J BIOL MACROMOL, V163, P1707, DOI 10.1016/j.ijbiomac.2020.09.109
   Bullard KM, 1999, ANN SURG, V230, P260, DOI 10.1097/00000658-199908000-00017
   Bus SA, 2012, DIABETES-METAB RES, V28, P54, DOI 10.1002/dmrr.2240
   Caley MP, 2015, ADV WOUND CARE, V4, P225, DOI 10.1089/wound.2014.0581
   Caravaggi C, 2000, DIABETES CARE, V23, P1746, DOI 10.2337/diacare.23.12.1746
   Cassidy B, 2023, DIABETES RES CLIN PR, V205, DOI 10.1016/j.diabres.2023.110951
   Castleberry SA, 2016, ADV MATER, V28, P1809, DOI 10.1002/adma.201503565
   Cder Fda, 2006, Chronic cutaneous ulcer and Burn wounds-developing products for treatment
   Chang M, 2021, ACCOUNTS CHEM RES, V54, P1080, DOI 10.1021/acs.accounts.0c00864
   Chen CY, 2017, J WOUND OSTOMY CONT, V44, P536, DOI 10.1097/WON.0000000000000374
   Chiang N, 2017, J VASC SURG, V66, P564, DOI 10.1016/j.jvs.2017.02.050
   Chocarro-Wrona C, 2019, J EUR ACAD DERMATOL, V33, P484, DOI 10.1111/jdv.15391
   Christoffersson G, 2012, BLOOD, V120, P4653, DOI 10.1182/blood-2012-04-421040
   Cioce A, 2024, CELLS-BASEL, V13, DOI 10.3390/cells13070624
   Crafts TD, 2015, CYTOKINE, V71, P385, DOI 10.1016/j.cyto.2014.08.005
   Cullen B, 2002, WOUND REPAIR REGEN, V10, P16, DOI 10.1046/j.1524-475X.2002.10703.x
   Davis KE, 2020, WOUND REPAIR REGEN, V28, P97, DOI 10.1111/wrr.12741
   Davoodi P, 2018, ADV DRUG DELIVER REV, V132, P104, DOI 10.1016/j.addr.2018.07.002
   Dayya D, 2022, ADV WOUND CARE, V11, P666, DOI 10.1089/wound.2021.0016
   de Franciscis S, 2015, INT WOUND J, V12, P250, DOI 10.1111/iwj.12085
   Diaz-Gomez L, 2022, CARBOHYD POLYM, V278, DOI 10.1016/j.carbpol.2021.118924
   Doni A, 2015, J EXP MED, V212, P905, DOI 10.1084/jem.20141268
   Dumville JC, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009110.pub3
   Dumville JC, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009111.pub2
   Dumville JC, 2011, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009099.pub3, 10.1002/14651858.CD009101.pub2]
   Edmonds M, 2000, DIABETES-METAB RES, V16, pS51, DOI 10.1002/1520-7560(200009/10)16:1+<::AID-DMRR142>3.0.CO;2-S
   Edmonds M, 2009, INT J LOW EXTR WOUND, V8, P11, DOI 10.1177/1534734609331597
   Elgzyri T, 2014, EUR J VASC ENDOVASC, V48, P440, DOI 10.1016/j.ejvs.2014.06.041
   Elraiyah T, 2016, J VASC SURG, V63, p37S, DOI 10.1016/j.jvs.2015.10.002
   Estronca L, 2016, STEM CELL MANUFACTURING, P291, DOI 10.1016/B978-0-444-63265-4.00013-3
   Fagher K, 2015, J DIABETES COMPLICAT, V29, P1198, DOI 10.1016/j.jdiacomp.2015.07.023
   Famta P, 2024, J DRUG DELIV SCI TEC, V99, DOI 10.1016/j.jddst.2024.105977
   Fard AS, 2007, INT J CLIN PRACT, V61, P1931, DOI 10.1111/j.1742-1241.2007.01534.x
   Farsaei S, 2012, INT WOUND J, V9, P238, DOI 10.1111/j.1742-481X.2011.00888.x
   Fatima F, 2023, GELS-BASEL, V9, DOI 10.3390/gels9010021
   Fda Cder, 2024, Internet. FDA (2024)
   FELLSTROM B, 1989, KIDNEY INT, V36, P1099, DOI 10.1038/ki.1989.306
   Fernández-Montequín JI, 2009, INT WOUND J, V6, P432, DOI 10.1111/j.1742-481X.2009.00641.x
   Ferraresi R., 2014, PanVascular Med, P1, DOI [10.1007/978-3-642-37393-0135-1, DOI 10.1007/978-3-642-37393-0135-1]
   Flores-Escobar S, 2022, J CLIN MED, V11, DOI 10.3390/jcm11071911
   Frykberg Robert G, 2006, J Foot Ankle Surg, V45, pS1
   Gallelli G, 2020, INT WOUND J, V17, P485, DOI 10.1111/iwj.13299
   Game FL, 2012, DIABETES-METAB RES, V28, P119, DOI 10.1002/dmrr.2246
   Ganier C., 2020, Textbook on Scar Management, P451, DOI DOI 10.1007/978-3-030-44766-3_51
   Gardner JC, 2016, AM J PHYSIOL-LUNG C, V310, pL868, DOI 10.1152/ajplung.00363.2015
   Gilligan AM, 2015, WOUND REPAIR REGEN, V23, P353, DOI 10.1111/wrr.12285
   Glat P, 2019, PRS-GLOB OPEN, V7, DOI 10.1097/GOX.0000000000002371
   Glover K, 2021, INT J PHARMACEUT, V599, DOI 10.1016/j.ijpharm.2021.120423
   Gomez-Villa R, 2014, WOUND REPAIR REGEN, V22, P497, DOI 10.1111/wrr.12187
   Gooyit M, 2014, ACS CHEM BIOL, V9, P105, DOI 10.1021/cb4005468
   Gopal S, 2020, FRONT IMMUNOL, V11, DOI 10.3389/fimmu.2020.00227
   Gordillo G.M., P WOUND HEAL SOC S A
   Gordon Katherine A, 2012, Skinmed, V10, P24
   Greene AK, 2006, ANN PLAS SURG, V56, P418, DOI 10.1097/01.sap.0000202831.43294.02
   Grennan D., 2019, JAMA-J AM MED ASSOC, V321, P114, DOI [10.1001/jama.2018.18323, DOI 10.1001/JAMA.2018.18323]
   Grip J, 2018, EUR J PHARM SCI, V121, P269, DOI 10.1016/j.ejps.2018.05.031
   Guo T, 2024, ECOTOX ENVIRON SAFE, V274, DOI 10.1016/j.ecoenv.2024.116212
   Gupta B, 2011, WOODHEAD PUBL MATER, P184
   Gupta R, 2025, J DRUG DELIV SCI TEC, V106, DOI 10.1016/j.jddst.2025.106681
   Gupta S.K., 2022, Decellularized extracellular matrices-based strategies in wound healing and skin tissue engineering, DOI [10.1016/B978-0-323-90514-5.00008-0, DOI 10.1016/B978-0-323-90514-5.00008-0]
   Gurtner GC, 2020, INT WOUND J, V17, P55, DOI 10.1111/iwj.13231
   Guyton GP, 2005, FOOT ANKLE INT, V26, P903, DOI 10.1177/107110070502601101
   Hamed S, 2010, J INVEST DERMATOL, V130, P287, DOI 10.1038/jid.2009.219
   Hanft J R, 2008, J Wound Care, V17, P30
   Henry G, 2003, SURG CLIN N AM, V83, P483, DOI 10.1016/S0039-6109(02)00200-1
   Hesselink JMK, 2018, DRUG DISCOV TODAY, V23, P402, DOI [10.1016/j.drudis.2017.09.020, 10.1016/j.drudis.2017.09.02, 10.1016/j.drudis.2017.09.020]
   Hilton JR, 2004, CLIN INFECT DIS, V39, pS100, DOI 10.1086/383270
   Hippen KL, 2022, FRONT IMMUNOL, V13, DOI 10.3389/fimmu.2022.926550
   Hiscox C., 2023, Characterization of bioengineered tissues by digital holographic vibrometry and 3D shape deep learning, P57, DOI [10.1007/978-3-031-17471-1_10, DOI 10.1007/978-3-031-17471-1_10]
   Hu ZC, 2016, J AM COLL SURGEONS, V222, P1171, DOI 10.1016/j.jamcollsurg.2016.02.023
   Huang X, 2020, LIFE SCI, V259, DOI 10.1016/j.lfs.2020.118246
   Hurlow J, 2012, ADV WOUND CARE, V1, P104, DOI 10.1089/wound.2011.0286
   Hyperbaric Oxygen Therapy, 2021, Get the Facts
   I. M, 2021, austin J, Surg., V8, DOI [10.26420/austinjsurg.2021.1280, DOI 10.26420/AUSTINJSURG.2021.1280]
   Jafari NJ, 2014, INT J ENDOCRINOL MET, V12, DOI 10.5812/ijem.13376
   Janka-Zires M, 2016, J DIABETES RES, V2016, DOI 10.1155/2016/7340641
   Jarczyk G, 2008, ACTA ANGIOL, V14, P42
   2016, Nature India, DOI [10.1038/nindia.2016.61, 10.1038/nindia.2016.61, DOI 10.1038/NINDIA.2016.61]
   Jones JI, 2019, PHARMACEUTICALS-BASE, V12, DOI 10.3390/ph12020079
   Jude EB, 2007, DIABETIC MED, V24, P280, DOI 10.1111/j.1464-5491.2007.02079.x
   Kalvaityte U, 2022, J ORTHOP TRANSL, V32, P77, DOI 10.1016/j.jot.2021.10.001
   Kanaujia KA, 2024, J DRUG DELIV SCI TEC, V95, DOI 10.1016/j.jddst.2024.105570
   Kanaujiya S, 2024, INT J NANOMED, V19, P5397, DOI 10.2147/IJN.S464046
   Karam RA, 2018, GENE, V667, P56, DOI 10.1016/j.gene.2018.05.032
   Kasiewicz LN, 2019, BIOENG TRANSL MED, V4, P75, DOI 10.1002/btm2.10123
   Kavitha KV, 2014, WORLD J DIABETES, V5, P546, DOI 10.4239/wjd.v5.i4.546
   Kazemi-Khoo N., 2006, The Foot, V16, P184, DOI [DOI 10.1016/J.FOOT.2006.05.004, 10.1016/j.foot.2006.05.004]
   Kim Hee Jung, 2017, Dev Reprod, V21, P1, DOI [10.12717/dr.2017.21.1.001, 10.12717/DR.2017.21.1.001]
   Ko A, 2023, BMEMAT, V1, DOI 10.1002/bmm2.12037
   Kolipaka T, 2024, CARBOHYD POLYM, V324, DOI 10.1016/j.carbpol.2023.121537
   Kolipaka T, 2023, INT J PHARMACEUT, V643, DOI 10.1016/j.ijpharm.2023.123278
   Kondo M, 2020, EMERG TOP LIFE SCI, V4, P677, DOI 10.1042/ETLS20200151
   Kottaisamy CPD, 2021, LAB ANIM RES, V37
   Krishnaswamy VR, 2014, CELL TISSUE RES, V358, P833, DOI 10.1007/s00441-014-2000-z
   Kumar RJ, 2004, ANZ J SURG, V74, P622, DOI 10.1111/j.1445-1433.2004.03106.x
   Lavery LA, 2020, AM J SURG, V220, P1076, DOI 10.1016/j.amjsurg.2020.02.044
   Lehn A., 2020, Platelet-rich plasma in tissue engineering, P477
   Li GW, 2017, ACTA DIABETOL, V54, P823, DOI 10.1007/s00592-017-1012-z
   Li R, 2016, BIOCHEM BIOPH RES CO, V474, P15, DOI 10.1016/j.bbrc.2016.03.112
   Liang Y, 2019, APOPTOSIS, V24, P542, DOI 10.1007/s10495-019-01536-w
   Liang ZH, 2023, DIABETIC MED, V40, DOI 10.1111/dme.14968
   Lipsky BA, 2020, DIABETES-METAB RES, V36, DOI 10.1002/dmrr.3280
   Liu Y, 2021, FRONT ENDOCRINOL, V12, DOI 10.3389/fendo.2021.744868
   Löndahl M, 2013, MED CLIN N AM, V97, P957, DOI 10.1016/j.mcna.2013.04.004
   Lyttle BD, 2023, FRONT MED-LAUSANNE, V10, DOI 10.3389/fmed.2023.1140979
   J LPM, 2018, International Surgery Journal, V5, P1008, DOI [10.18203/2349-2902.isj20180821, 10.18203/2349-2902.isj20180821, DOI 10.18203/2349-2902.ISJ20180821]
   Madhukiran DR, 2021, EXPERT OPIN DRUG DEL, V18, P25, DOI 10.1080/17425247.2021.1823966
   Magalhaes J, 2011, J NEUROPATH EXP NEUR, V70, P1097, DOI 10.1097/NEN.0b013e31823a44f4
   Maranna H, 2021, DIABETES METAB SYND, V15, P365, DOI 10.1016/j.dsx.2021.01.014
   Marfella R, 2012, EXP DIABETES RES, DOI 10.1155/2012/892706
   Margolin L, 2010, INT WOUND J, V7, P202, DOI 10.1111/j.1742-481X.2010.00234.x
   Margolis DJ, 2010, WOUND REPAIR REGEN, V18, P445, DOI 10.1111/j.1524-475X.2010.00624.x
   McDermott K, 2023, DIABETES CARE, V46, P209, DOI 10.2337/dci22-0043
   McFadyen JD, 2018, FRONT IMMUNOL, V9, DOI 10.3389/fimmu.2018.01351
   Meloni M, 2021, J CLIN MED, V10, DOI 10.3390/jcm10173977
   Mitchell AC, 2016, ACTA BIOMATER, V30, P1, DOI 10.1016/j.actbio.2015.11.007
   Mohammadi MH, 2017, TRANSFUS APHER SCI, V56, P160, DOI 10.1016/j.transci.2016.10.020
   Morley S, 2013, BRIT J DERMATOL, V168, P617, DOI 10.1111/bjd.12098
   Morra A.R., 2019, Advanced wound healing: neuropathic foot, DOI [10.1007/978-3-319-17918-6_7, DOI 10.1007/978-3-319-17918-6_7]
   Moura LIF, 2013, ACTA BIOMATER, V9, P7093, DOI 10.1016/j.actbio.2013.03.033
   Mousa KM, 2023, SAGE OPEN NURS, V9, DOI 10.1177/23779608231185873
   Muller M, 2008, DIABETIC MED, V25, P419, DOI 10.1111/j.1464-5491.2008.02414.x
   Nabuurs-Ranssen MH, 2005, DIABETES CARE, V28, P243, DOI 10.2337/diacare.28.2.243
   Naguib G, 2004, J INVEST DERMATOL, V123, P87, DOI 10.1111/j.0022-202X.2004.22711.x
   Ngo TD, 2018, COMPOS PART B-ENG, V143, P172, DOI [10.1017/s136898001800037x, 10.1016/j.compositesb.2018.02.012]
   Nielsen J, 2015, CHRONIC WOUND CARE M, V2, P31, DOI 10.2147/CWCMR.S50832
   Nik Hisamuddin N A R, 2019, Med J Malaysia, V74, P418
   Norgren L, 2007, J VASC SURG, V45, pS5, DOI 10.1016/j.jvs.2006.12.037
   Nwomeh BC, 1998, CLIN PLAST SURG, V25, P341
   OGATA Y, 1992, J BIOL CHEM, V267, P3581
   organogenesis, Hope for gealing your Diabetic Foot Ulcer
   Pakyari M, 2013, ADV WOUND CARE, V2, P215, DOI 10.1089/wound.2012.0406
   Panda D, 2024, STEM CELL REV REP, V20, P88, DOI 10.1007/s12015-023-10640-z
   Pandey G., 2024, BIOMATER INSP NANOME, P31, DOI 10.1007/978-981-97-3925
   Pandey G, 2024, J DRUG DELIV SCI TEC, V91, DOI 10.1016/j.jddst.2023.105249
   Pandey G, 2024, INT J BIOL MACROMOL, V256, DOI 10.1016/j.ijbiomac.2023.128452
   Pandey G, 2023, INT J PHARMACEUT, V638, DOI 10.1016/j.ijpharm.2023.122918
   Pappachan JM, 2022, WORLD J DIABETES, V13, P1131, DOI 10.4239/wjd.v13.i12.1131
   Park KH, 2018, DIABETES RES CLIN PR, V142, P335, DOI 10.1016/j.diabres.2018.06.002
   Perez LA, 2022, FRONT CELL DEV BIOL, V10, DOI 10.3389/fcell.2022.810474
   Pichu S, 2017, BIOMARK MED, V11, P377, DOI 10.2217/bmm-2016-0205
   Przekora A, 2020, CELLS-BASEL, V9, DOI 10.3390/cells9071622
   Qi XL, 2024, ACS MATER LETT, V6, P2533, DOI 10.1021/acsmaterialslett.4c00392
   Qi XL, 2024, ADV FUNCT MATER, V34, DOI 10.1002/adfm.202400489
   Qi XL, 2023, ADV MATER, V35, DOI 10.1002/adma.202306632
   Qi XL, 2023, COORDIN CHEM REV, V496, DOI 10.1016/j.ccr.2023.215426
   Qi XL, 2022, ADV SCI, V9, DOI 10.1002/advs.202106015
   Rabbani PS, 2017, BIOMATERIALS, V132, P1, DOI 10.1016/j.biomaterials.2017.04.001
   Radji M, 2014, DIABETES METAB SYND, V8, P221, DOI 10.1016/j.dsx.2014.09.006
   Ramundo J, 2008, J WOUND OSTOMY CONT, V35, P273, DOI 10.1097/01.WON.0000319125.21854.78
   Rao SS, 2020, J DRUG DELIV SCI TEC, V55, DOI 10.1016/j.jddst.2019.101385
   Rastan A, 2015, J ENDOVASC THER, V22, P839, DOI 10.1177/1526602815608610
   Reddy P, 2004, CURR OPIN HEMATOL, V11, P405, DOI 10.1097/01.moh.0000141926.95319.42
   Redhwan Moqbel Ali Moqbel, 2023, OpenNano, DOI [10.1016/j.onano.2023.100174, 10.1016/j.onano.2023.100174]
   Reyzelman A, 2009, INT WOUND J, V6, P196, DOI 10.1111/j.1742-481X.2009.00585.x
   RICHARD JL, 1995, DIABETES CARE, V18, P64, DOI 10.2337/diacare.18.1.64
   Rider P, 2018, J TISSUE ENG, V9, DOI 10.1177/2041731418802090
   Rocha Júnior Adeir Moreira, 2007, J. vasc. bras., V6, P257
   Russo S, 2022, CLINICOECONOMIC OUTC, V14, P1, DOI 10.2147/CEOR.S327191
   Sabuncu T, 2014, J AM PODIAT MED ASSN, V104, P222, DOI 10.7547/0003-0538-104.3.222
   Saeedi P, 2019, DIABETES RES CLIN PR, V157, DOI 10.1016/j.diabres.2019.107843
   Salama SE, 2019, INT J LOW EXTR WOUND, V18, P75, DOI 10.1177/1534734619829939
   Samaga MP, 2012, J PURE APPL MICROBIO, V6, P2033
   Savoji H, 2018, FRONT BIOENG BIOTECH, V6, DOI 10.3389/fbioe.2018.00086
   Schaper N C., 2019, IWGDF Guidelines
   Schultz GS, 2003, WOUND REPAIR REGEN, V11, pS1, DOI 10.1046/j.1524-475X.11.s2.1.x
   Seidel D, 2022, J FOOT ANKLE RES, V15, DOI 10.1186/s13047-022-00569-w
   Selvarajah D, 2019, INT J BURNS TRAUMA, V9, P82
   Serra R, 2016, INT WOUND J, V13, P53, DOI 10.1111/iwj.12225
   Sethuram L, 2022, NANOSCALE ADV, V4, P2367, DOI 10.1039/d1na00859e
   Shaabani E, 2021, INT J MOL SCI, V22, DOI 10.3390/ijms22179216
   Shah SR, 2025, BIONANOSCIENCE, V15, DOI 10.1007/s12668-025-01833-6
   Shah SR, 2025, DRUG DEV IND PHARM, V51, P132, DOI 10.1080/03639045.2025.2453533
   Shah SR, 2023, INT J PHARMACEUT, V634, DOI 10.1016/j.ijpharm.2023.122633
   Shah SMAH, 2023, HEALTHCARE-BASEL, V11, DOI 10.3390/healthcare11212840
   Shams F, 2022, SCI REP-UK, V12, DOI 10.1038/s41598-022-23304-8
   Sharma P, 2021, LIFE SCI, V268, DOI 10.1016/j.lfs.2020.118932
   Slattery ML, 2018, MOL CARCINOGEN, V57, P243, DOI 10.1002/mc.22752
   Smith RG, 2008, OSTOMY WOUND MANAG, V54, P16
   Spampinato SF, 2020, PHARMACEUTICALS-BASE, V13, DOI 10.3390/ph13040060
   Steed DL, 2006, PLAST RECONSTR SURG, V117, p143S, DOI 10.1097/01.prs.0000222526.21512.4c
   Stevens CD, 2014, HEALTH AFFAIR, V33, P1383, DOI 10.1377/hlthaff.2014.0148
   Stoekenbroek RM, 2015, J DIABETES, V7, P125, DOI 10.1111/1753-0407.12155
   Sufianov A, 2023, NON-CODING RNA RES, V8, P392, DOI 10.1016/j.ncrna.2023.05.008
   Sullivan TP, 2001, WOUND REPAIR REGEN, V9, P66, DOI 10.1046/j.1524-475x.2001.00066.x
   Sun H, 2022, DIABETES RES CLIN PR, V183, DOI 10.1016/j.diabres.2021.109119
   Takashi Y, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0196526
   Tallis A, 2013, CLIN THER, V35, P1805, DOI 10.1016/j.clinthera.2013.09.013
   Tan CT, 2020, BIOMEDICINES, V8, DOI 10.3390/biomedicines8100441
   Tan MLL, 2023, EXPERT OPIN DRUG DIS, V18, P99, DOI 10.1080/17460441.2023.2158809
   Tavakoli M, 2023, J APPL POLYM SCI, V140, DOI 10.1002/app.53910
   Tchanque-Fossuo CN, 2019, J TISSUE ENG REGEN M, V13, P1430, DOI 10.1002/term.2884
   Tecilazich F, 2013, EXPERT OPIN EMERG DR, V18, P207, DOI 10.1517/14728214.2013.802305
   Teobaldi I, 2018, ENDOCRINOL DIAB META, DOI 10.1530/EDM-18-0117
   Teodoro JS, 2019, FRONT PHYSIOL, V9, DOI 10.3389/fphys.2018.01857
   Thomas B, 2017, J VASC SURG-VENOUS L, V5, P844, DOI 10.1016/j.jvsv.2017.04.019
   Tran TDX, 2014, BIOMED RES THER, V1, P37, DOI 10.7603/s40730-014-0008-3
   Uchi H, 2009, EUR J DERMATOL, V19, P461, DOI 10.1684/ejd.2009.0750
   Umapathy D, 2018, J VASC SURG, V67, P1283, DOI 10.1016/j.jvs.2017.02.060
   van Kogelenberg S, 2018, ADV WOUND CARE, V7, P145, DOI 10.1089/wound.2017.0752
   Visse R, 2003, CIRC RES, V92, P827, DOI 10.1161/01.RES.0000070112.80711.3D
   Viswanathan V, 2020, INT J LOW EXTR WOUND, V19, P158, DOI 10.1177/1534734619892791
   Wang C, 2020, BIOACT MATER, V5, P82, DOI 10.1016/j.bioactmat.2020.01.004
   Wang C, 2019, COMPLEMENT THER CLIN, V34, P123, DOI 10.1016/j.ctcp.2018.09.004
   Wang J, 2020, CYTOKINE, V133, DOI 10.1016/j.cyto.2020.155173
   Wang X, 2020, FRONT CHEM, V8, DOI 10.3389/fchem.2020.00245
   Wang YQ, 2021, BIOMED PHARMACOTHER, V133, DOI 10.1016/j.biopha.2020.110991
   Weatherall T, 2024, J TISSUE VIABILITY, V33, P853, DOI 10.1016/j.jtv.2024.07.004
   Weigelt M.A., 2022, Dressings and wound care supplies for hidradenitis suppurativa, DOI [10.1016/B978-0-323-77724-7.00020-6, DOI 10.1016/B978-0-323-77724-7.00020-6]
   Wen X, 2022, ECOTOX ENVIRON SAFE, V231, DOI 10.1016/j.ecoenv.2022.113207
   Wetterau M, 2011, WOUND REPAIR REGEN, V19, P481, DOI 10.1111/j.1524-475X.2011.00697.x
   Widodo A, 2020, ANN MED SURG, V58, P187, DOI 10.1016/j.amsu.2020.08.009
   Wu HJ, 2023, ADV WOUND CARE, V12, P28, DOI 10.1089/wound.2021.0162
   Wu SC, 2008, DIABETES CARE, V31, P2118, DOI 10.2337/dc08-0771
   Xie XY, 2012, J AM PODIAT MED ASSN, V102, P299, DOI 10.7547/1020299
   Xiong Y, 2020, SMALL, V16, DOI 10.1002/smll.201904044
   Xu Y, 2020, J CELL MOL MED, V24, P13789, DOI 10.1111/jcmm.15958
   Yamakawa S, 2019, BURNS TRAUMA, V7, DOI 10.1186/s41038-019-0148-1
   Yanez M, 2015, TISSUE ENG PT A, V21, P224, DOI [10.1089/ten.tea.2013.0561, 10.1089/ten.TEA.2013.0561]
   Yang B, 2014, J SURG RES, V186, P63, DOI 10.1016/j.jss.2013.07.044
   Yang Q, 2020, ANN VASC SURG, V62, P442, DOI 10.1016/j.avsg.2019.05.041
   Yao M, 2013, J AM PODIAT MED ASSN, V103, P274, DOI 10.7547/1030274
   Yazdanpanah L, 2015, WORLD J DIABETES, V6, P37, DOI 10.4239/wjd.v6.i1.37
   Yue C, 2020, STEM CELLS INT, V2020, DOI 10.1155/2020/7430968
   Zhang SF, 2009, PHARM RES-DORDR, V26, P1561, DOI 10.1007/s11095-009-9897-z
   Zhang XY, 2015, CELL BIOCHEM BIOPHYS, V72, P777, DOI 10.1007/s12013-015-0531-x
   Zhang XY, 2024, BIOMED PHARMACOTHER, V179, DOI 10.1016/j.biopha.2024.117386
   Zhang ZX, 2025, ISCIENCE, V28, DOI 10.1016/j.isci.2024.111705
   Zhao DY, 2020, INT WOUND J, V17, P1062, DOI 10.1111/iwj.13377
   Zhao P, 2017, AGING CELL, V16, P1083, DOI 10.1111/acel.12635
   Zheng L, 2009, AM J PATHOL, V175, P1905, DOI 10.2353/ajpath.2009.080705
   Zhou P, 2021, FRONT ENDOCRINOL, V12, DOI 10.3389/fendo.2021.734485
   Zhu YQ, 2009, J ENDOVASC THER, V16, P604, DOI 10.1583/09-2793.1
   Zubair M, 2019, REV ENDOCR METAB DIS, V20, P207, DOI 10.1007/s11154-019-09492-1
NR 263
TC 12
Z9 12
U1 10
U2 32
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 1773-2247
EI 2588-8943
J9 J DRUG DELIV SCI TEC
JI J. Drug Deliv. Sci. Technol.
PD MAY
PY 2025
VL 107
AR 106852
DI 10.1016/j.jddst.2025.106852
EA MAR 2025
PG 30
WC Pharmacology & Pharmacy
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Pharmacology & Pharmacy
GA 0ZW2S
UT WOS:001459966300001
DA 2026-07-24
ER

PT J
AU Toogood, P
   Miclau, T
AF Toogood, Paul
   Miclau, Theodore
TI Critical-Sized Bone Defects: Sequence and Planning
SO JOURNAL OF ORTHOPAEDIC TRAUMA
LA English
DT Article
DE bone defect; soft tissue management; trauma
ID PRESSURE WOUND THERAPY; SEVERE OPEN FRACTURES; DEEP-INFECTION-RATE;
   EXTRUDED TALUS; TIBIAL SHAFT; ANTIBIOTIC-PROPHYLAXIS; FLAP COVERAGE;
   MANAGEMENT; REIMPLANTATION; CLOSURE
AB Bone defects associated with open fractures require a careful approach and planning. At initial presentation, an emergent irrigation and debridement is required. Immediate definitive fixation is frequently safe, with the exception of those injuries that normally require staged management or very severe type IIIB and IIIC injuries. Traumatic wounds that can be approximated primarily should be closed at the time of initial presentation. Wounds that cannot be closed should have a negative pressure wound therapy dressing applied. The need for subsequent debridements remains a clinical judgment, but all nonviable tissue should be removed before definitive coverage. Cefazolin remains the standard of care for all open fractures, and type III injuries also require gram-negative coverage. Both induced membrane technique with staged bone grafting and distraction osteogenesis are excellent options for bony reconstruction. Soft tissue coverage within 1 week of injury seems critical.
C1 [Toogood, Paul; Miclau, Theodore] Univ Calif San Francisco, UCSF ZSFG Orthoped Trauma Inst, Dept Orthopaed Surg, 2550 23rd St,Bldg 9,2nd Floor, San Francisco, CA 94110 USA.
C3 University of California System; University of California San Francisco
RP Toogood, P (通讯作者)，Univ Calif San Francisco, UCSF ZSFG Orthoped Trauma Inst, Dept Orthopaed Surg, 2550 23rd St,Bldg 9,2nd Floor, San Francisco, CA 94110 USA.
EM Paul.toogood@ucsf.edu
FU NIAMS NIH HHS [R01 AR057344, R01 AR053645, R21 AR066847] Funding Source:
   Medline
CR ABELL CF, 1966, J BONE JOINT SURG AM, VA 48, P537, DOI 10.2106/00004623-196648030-00014
   [Anonymous], ANN M ORTH TRAUM ASS
   Apostle KL, 2010, J BONE JOINT SURG AM, V92A, P1661, DOI 10.2106/JBJS.I.00867
   BENSON DR, 1983, J TRAUMA, V23, P25, DOI 10.1097/00005373-198301000-00005
   Blum ML, 2012, J ORTHOP TRAUMA, V26, P499, DOI 10.1097/BOT.0b013e31824133e3
   Bosse MJ, 2017, J ORTHOP TRAUMA, V31, pS3, DOI [10.1097/bot.0000000000000805, 10.1097/BOT.0000000000000805]
   Breccia Marco, 2014, Foot (Edinb), V24, P89, DOI 10.1016/j.foot.2014.03.008
   Brewster NT, 1997, J ORTHOP TRAUMA, V11, P42, DOI 10.1097/00005131-199701000-00011
   BRUMBACK RJ, 1989, J BONE JOINT SURG AM, V71A, P1324, DOI 10.2106/00004623-198971090-00007
   Burston JL, 2011, J FOOT ANKLE SURG, V50, P104, DOI 10.1053/j.jfas.2010.10.009
   Carver DC, 2017, ORTHOP CLIN N AM, V48, P137, DOI [10.1016/j.oc1.2016.12.005, 10.1016/j.ocl.2016.12.005]
   D'Alleyrand JCG, 2014, J ORTHOP TRAUMA, V28, P288, DOI 10.1097/BOT.0000000000000001
   Dedmond BT, 2007, J ORTHOP TRAUMA, V21, P11, DOI 10.1097/BOT.0b013e31802cbc54
   DELLINGER EP, 1988, ARCH SURG-CHICAGO, V123, P333
   Dumbre Patil Sampat Shivajirao, 2014, Foot Ankle Spec, V7, P427, DOI 10.1177/1938640014528040
   FISCHER MD, 1991, J BONE JOINT SURG AM, V73A, P1316, DOI 10.2106/00004623-199173090-00005
   Fleming J, 2009, J FOOT ANKLE SURG, V48, DOI 10.1053/j.jfas.2009.06.005
   Gerken N, 2011, J ORTHOP TRAUMA, V25, pE107, DOI 10.1097/BOT.0b013e318210f236
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Henley MB, 1998, J ORTHOP TRAUMA, V12, P1, DOI 10.1097/00005131-199801000-00001
   Hoff WS, 2011, J TRAUMA, V70, P751, DOI 10.1097/TA.0b013e31820930e5
   Jenkinson RJ, 2014, J BONE JOINT SURG AM, V96A, P380, DOI 10.2106/JBJS.L.00545
   Johnson K D, 1988, J Orthop Trauma, V2, P175, DOI 10.1097/00005131-198802030-00001
   KAO JT, 1995, J ORTHOP TRAUMA, V9, P336, DOI 10.1097/00005131-199509040-00011
   KIRKUP J R, 1965, J Bone Joint Surg Br, V47, P106
   Lack WD, 2015, J ORTHOP TRAUMA, V29, P1, DOI [10.1097/bot.0000000000000262, 10.1097/BOT.0000000000000262, 10.1016/j.mporth.2014.12.008]
   Lee HS, 2014, CLIN ORTHOP SURG, V6, P236, DOI 10.4055/cios.2014.6.2.236
   Lee J, 1997, CLIN ORTHOP RELAT R, P71
   Luchette FA, 2000, Eastern Association Surg of Trauma
   Mnif H, 2010, J FOOT ANKLE SURG, V49, P172, DOI 10.1053/j.jfas.2009.09.003
   Mohammad HR, 2017, ANN ROY COLL SURG, V99, pE125, DOI 10.1308/rcsann.2017.0042
   Morelli I, 2016, INJURY, V47, pS68, DOI 10.1016/S0020-1383(16)30842-7
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Murray CK, 2008, J TRAUMA, V64, pS239, DOI 10.1097/TA.0b013e318163cd14
   Palmer MP, 2014, J ORTHOP TRAUMA, V28, P384, DOI 10.1097/BOT.0000000000000043
   Papakostidis C, 2013, BONE JOINT J, V95B, P1673, DOI 10.1302/0301-620X.95B12.32385
   PATZAKIS MJ, 1983, CLIN ORTHOP RELAT R, P31
   PATZAKIS MJ, 1974, J BONE JOINT SURG AM, VA 56, P532, DOI 10.2106/00004623-197456030-00010
   Pollak AN, 2000, J BONE JOINT SURG AM, V82A, P1681, DOI 10.2106/00004623-200012000-00001
   Redfern J, 2016, J ORTHOP TRAUMA, V30, P415, DOI 10.1097/BOT.0000000000000554
   Rodriguez L, 2014, J TRAUMA ACUTE CARE, V77, P400, DOI 10.1097/TA.0000000000000398
   Smith CS, 2006, J BONE JOINT SURG AM, V88A, P2418, DOI 10.2106/JBJS.E.00471
   Stannard JP, 2009, J ORTHOP TRAUMA, V23, P552, DOI 10.1097/BOT.0b013e3181a2e2b6
   Templeman DC, 1998, CLIN ORTHOP RELAT R, P18
   TORNETTA P, 1994, J BONE JOINT SURG BR, V76B, P13, DOI 10.1302/0301-620X.76B1.8300656
   Webb LX, 2007, J BONE JOINT SURG AM, V89A, P923, DOI 10.2106/JBJS.F.00776
   YAREMCHUK MJ, 1986, CLIN PLAST SURG, V13, P621
   Zalavras Charalampos G, 2003, J Am Acad Orthop Surg, V11, P212
NR 49
TC 25
Z9 28
U1 0
U2 12
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0890-5339
EI 1531-2291
J9 J ORTHOP TRAUMA
JI J. Orthop. Trauma
PD OCT
PY 2017
VL 31
SU 5
BP S23
EP S26
DI 10.1097/BOT.0000000000000980
PG 4
WC Orthopedics; Sport Sciences
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Sport Sciences
GA FK2DR
UT WOS:000413293300006
PM 28938387
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Almuhanna, Y
AF Almuhanna, Yasir
TI Microbial Biofilms as Barriers to Chronic Wound Healing: Diagnostic
   Challenges and Therapeutic Advances
SO JOURNAL OF CLINICAL MEDICINE
LA English
DT Review
DE biofilm; chronic; wound; healing; diagnostic; therapeutic; microbiome;
   resistance
ID DISRUPTING AGENT; CARE; ULCERS
AB Wound healing is a complex and multistage process that incorporates precise cellular and molecular coordination. The presence of biofilms in chronic wounds adversely affects the wound healing process, as it prolongs the closure of the wound, thus sustaining chronic inflammation. Current data suggest that biofilms are present in almost all chronic wounds, which leads to significant challenges in diagnosis and treatment. Traditional detection methods, such as cultures and light microscopy, often fail to detect biofilms; however, sophisticated molecular and imaging techniques are constrained by their expense and accessibility. Chronic wound management, therefore, has progressed from conventional antimicrobial application to integrated methodologies that incorporate biofilm debridement, antibiofilm dressing, negative pressure wound therapy, and innovative enzyme or nanoparticle interventions. This review highlights the clinical significance of biofilm presence as a barrier in chronic wound healing, assesses diagnostic and therapeutic innovations, and stresses the urgent need to improve patient outcomes.
C1 [Almuhanna, Yasir] Shaqra Univ, Coll Appl Med Sci, Dept Clin Lab Sci, Shaqra 11961, Saudi Arabia.
C3 Shaqra University
RP Almuhanna, Y (通讯作者)，Shaqra Univ, Coll Appl Med Sci, Dept Clin Lab Sci, Shaqra 11961, Saudi Arabia.
EM yalmuhanna@su.edu.sa
RI Almuhanna, Yasir/GQA-8504-2022
OI Almuhanna, Yasir/0000-0001-9080-6056
FU Deanship of Scientific Research at Shaqra University
FX The author would like to thank the Deanship of Scientific Research at
   Shaqra University for supporting this work.
CR Afonso AC, 2021, INT J MOL SCI, V22, DOI 10.3390/ijms22158278
   Armstrong DG, 2023, INT WOUND J, V20, P554, DOI 10.1111/iwj.14080
   Astrada A, 2026, FOOT ANKLE SPEC, V19, P29, DOI [10.1177/19386400231225708, 10.1177/19386400231225708]
   Atkin L, 2019, J WOUND CARE, V28, pS5, DOI 10.12968/jowc.2019.28.Sup3a.S1
   Bach MS, 2022, CELL REP MED, V3, DOI 10.1016/j.xcrm.2022.100656
   Baker P, 2016, SCI ADV, V2, DOI 10.1126/sciadv.1501632
   Barbosa A, 2023, FRONT CELL INFECT MI, V13, DOI 10.3389/fcimb.2023.1195803
   Barki KG, 2019, ANN SURG, V269, P756, DOI 10.1097/SLA.0000000000002504
   Barrigah-Benissan K, 2022, ANTIBIOTICS-BASEL, V11, DOI 10.3390/antibiotics11030350
   Bjarnsholt T, 2017, WOUNDS INT, V8, P1
   Boleti APD, 2025, PHARMACEUTICALS-BASE, V18, DOI 10.3390/ph18101525
   Cavallo I, 2024, BIOLOGY-BASEL, V13, DOI 10.3390/biology13020109
   Chandra P, 2026, CURR DIABETES REV, V22, DOI 10.2174/0115733998332692241202072249
   Chen XF, 2021, WOUND REPAIR REGEN, V29, P820, DOI 10.1111/wrr.12944
   Dawan J, 2025, ANTIBIOTICS-BASEL, V14, DOI 10.3390/antibiotics14030254
   Fernandez-Guarino M, 2024, COSMETICS-BASEL, V11, DOI 10.3390/cosmetics11060209
   Gajula B, 2020, International Journal of Surgery: Global Health, V3, pe16, DOI [10.1097/gh9.0000000000000016, 10.1097/gh9.0000000000000016, DOI 10.1097/GH9.0000000000000016, 10.1097/GH9.0000000000000016]
   Goswami AG, 2023, EUR J MED RES, V28, DOI 10.1186/s40001-023-01121-7
   Hurlow J, 2016, J WOUND CARE, V25, pS11, DOI 10.12968/jowc.2016.25.Sup9.S11
   Iversen AKS, 2024, BMJ OPEN, V14, DOI 10.1136/bmjopen-2024-084081
   Jacob A, 2023, INT WOUND J, V20, P3279, DOI 10.1111/iwj.14208
   Jeckel Hannah, 2022, PLoS Biol, V20, pe3001846, DOI 10.1371/journal.pbio.3001846
   Johani K, 2017, INT WOUND J, V14, P1160, DOI 10.1111/iwj.12777
   Kim D, 2018, WOUNDS, V30, P120
   Kim JH, 2020, FRONT CELL INFECT MI, V10, DOI 10.3389/fcimb.2020.00259
   Kim JS, 2023, FOOD SCI BIOTECHNOL, V32, P1745, DOI 10.1007/s10068-023-01373-3
   Kundukad B, 2025, NPJ BIOFILMS MICROBI, V11, DOI 10.1038/s41522-025-00718-6
   Lenselink E, 2011, J WOUND CARE, V20, P534, DOI 10.12968/jowc.2011.20.11.534
   Li L, 2013, BURNS TRAUMA, V1, DOI 10.4103/2321-3868.113331
   Li X, 2020, J DIABETES RES, V2020, DOI 10.1155/2020/9589507
   Lichtenberg M, 2024, APMIS, V132, P1071, DOI 10.1111/apm.13344
   Liu Y, 2024, INT WOUND J, V21, DOI 10.1111/iwj.14667
   Luo HY, 2025, COMMUN BIOL, V8, DOI 10.1038/s42003-025-08754-w
   Mañas CR, 2025, J WOUND CARE, V34, P278, DOI [10.12968/jowc.2024.0170, 10.12968/jowc.2024.0170]
   Marano RJ, 2015, SCI REP-UK, V5, DOI 10.1038/srep13296
   Mariana Peroni, 2024, International Journal of Scientific Research Updates, V8, P077, DOI [10.53430/ijsru.2024.8.2.0060, 10.53430/ijsru.2024.8.2.0060, DOI 10.53430/IJSRU.2024.8.2.0060]
   Matheus GG, 2025, BURNS TRAUMA, V13, DOI 10.1093/burnst/tkae083
   Mayer P, 2024, DIAGNOSTICS, V14, DOI 10.3390/diagnostics14192116
   Mikzinski P, 2024, MICROORGANISMS, V12, DOI 10.3390/microorganisms12061198
   Miller KG, 2014, ANTIMICROB AGENTS CH, V58, P3060, DOI 10.1128/AAC.00108-14
   Mori Y, 2019, WOUND REPAIR REGEN, V27, P540, DOI 10.1111/wrr.12738
   Namgoong S, 2020, J PLAST SURG HAND SU, V54, P47, DOI 10.1080/2000656X.2019.1673170
   Nesporová K, 2020, SCI REP-UK, V10, DOI 10.1038/s41598-020-72249-3
   Nguyen KT, 2013, WOUND REPAIR REGEN, V21, P833, DOI 10.1111/wrr.12109
   O'Meara S, 2013, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD003557.pub4, 10.1002/14651858.CD003557.pub5]
   Parsons D, 2016, BIOMED RES INT, V2016, DOI 10.1155/2016/7616471
   Pastar I, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0056846
   Patel M.P.T., 2018, World J. Vasc. Surg, V1, P1015
   Peña OA, 2024, NAT REV MOL CELL BIO, V25, P599, DOI 10.1038/s41580-024-00715-1
   Penesyan A, 2021, NPJ BIOFILMS MICROBI, V7, DOI 10.1038/s41522-021-00251-2
   Pouget C, 2022, FRONT MICROBIOL, V13, DOI 10.3389/fmicb.2022.705479
   Pouget C, 2021, FRONT MICROBIOL, V12, DOI 10.3389/fmicb.2021.747618
   Prasad ASB, 2020, LAB INVEST, V100, P1532, DOI 10.1038/s41374-020-00478-1
   Qi XL, 2025, Cell Biomaterials, V1, P100020, DOI [10.1016/j.celbio.2025.100020, 10.1016/j.celbio.2025.100020, DOI 10.1016/J.CELBIO.2025.100020]
   Ramakrishnan R, 2024, NPJ BIOFILMS MICROBI, V10, DOI 10.1038/s41522-024-00593-7
   Roy R, 2024, J INVEST DERMATOL, V144, DOI 10.1016/j.jid.2023.08.004
   Roy S, 2020, ANN SURG, V271, P1174, DOI 10.1097/SLA.0000000000003053
   Roy S, 2014, J PATHOL, V233, P331, DOI 10.1002/path.4360
   Rumbaugh KP, 2020, NAT REV MICROBIOL, V18, P571, DOI 10.1038/s41579-020-0385-0
   Schultz G, 2017, WOUND REPAIR REGEN, V25, P744, DOI 10.1111/wrr.12590
   Serena TE, 2021, J WOUND CARE, V30, P9, DOI 10.12968/jowc.2021.30.1.9
   Seth AK, 2012, PLAST RECONSTR SURG, V129, p262E, DOI 10.1097/PRS.0b013e31823aeb3b
   Shen AZ, 2025, J CLIN MED, V14, DOI 10.3390/jcm14217784
   Shi ZJ, 2023, FRONT PHYSIOL, V14, DOI 10.3389/fphys.2023.1284981
   Stewart PS, 2022, ANTIMICROB AGENTS CH, V66, DOI 10.1128/aac.00021-22
   Swanson T, 2022, J WOUND CARE, V31, pS10, DOI 10.12968/jowc.2022.31.Sup12.S10
   Torkington-Stokes R, 2024, J WOUND CARE, V33, P304, DOI 10.12968/jowc.2024.33.5.304
   Townsend EC, 2024, WOUND REPAIR REGEN, V32, P783, DOI 10.1111/wrr.13170
   Trostrup H, 2020, ANTIBIOTICS-BASEL, V9, DOI 10.3390/antibiotics9070396
   Trostrup H, 2017, PATHOG DIS, V75, DOI 10.1093/femspd/ftx110
   Walker M, 2015, J WOUND CARE, V24, P11, DOI 10.12968/jowc.2015.24.1.11
   Wang F, 2022, NANOTECHNOL REV, V11, P2493, DOI 10.1515/ntrev-2022-0122
   Wang XY, 2023, MOL BIOMED, V4, DOI 10.1186/s43556-023-00164-w
   Wasfi R, 2020, FRONT CELL INFECT MI, V10, DOI 10.3389/fcimb.2020.00414
   Watson F, 2024, INT WOUND J, V21, DOI 10.1111/iwj.14365
   Wei M, 2019, INT J CLIN EXP MED, V12, P12293
   Weigelt MA, 2021, ADV WOUND CARE, V10, P13, DOI 10.1089/wound.2020.1193
   Xiang YJ, 2024, BIOACT MATER, V39, P562, DOI 10.1016/j.bioactmat.2024.04.022
   Yang C, 2017, WOUNDS, V29, P240
   Yu D, 2024, FRONT CELL INFECT MI, V14, DOI 10.3389/fcimb.2024.1324441
   Zhao G, 2012, WOUND REPAIR REGEN, V20, P342, DOI 10.1111/j.1524-475X.2012.00793.x
   Zielinska M, 2023, INT J MOL SCI, V24, DOI 10.3390/ijms242417318
NR 82
TC 15
Z9 20
U1 10
U2 12
PU MDPI
PI BASEL
PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
EI 2077-0383
J9 J CLIN MED
JI J. Clin. Med.
PD NOV 17
PY 2025
VL 14
IS 22
AR 8121
DI 10.3390/jcm14228121
PG 16
WC Medicine, General & Internal
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA F8130
UT WOS:001623916500001
PM 41303157
OA gold
DA 2026-07-24
ER

PT J
AU Sugrue, M
AF Sugrue, Michael
TI Abdominal compartment syndrome and the open abdomen: any unresolved
   issues?
SO CURRENT OPINION IN CRITICAL CARE
LA English
DT Review
DE abdominal compartment syndrome; abdominal wall closure; open abdomen
ID DAMAGE-CONTROL LAPAROTOMY; SEVERE ACUTE-PANCREATITIS; INTRAABDOMINAL
   HYPERTENSION; FASCIAL CLOSURE; NONTRAUMA PATIENTS; PRESSURE;
   100-PERCENT; MANAGEMENT
AB Purpose of review
   This article reviews the key principles of abdominal compartment syndrome and the open abdomen, exploring some of the unresolved issues. It reviews new concepts in care.
   Recent findings
   Recent use of peritoneal resuscitation, and benefits of mesh-mediated traction are discussed. Abdominal compartment syndrome remains a result of complex interaction between general haemorrhage, sepsis and fluid resuscitation. Improved resuscitation and sepsis control has decreased but not abolished the need for the open abdomen and progression for abdominal compartment syndrome. Fourth-generation abdominal wall dressings need to be combined with a dynamic closure system; currently, negative pressure wound therapy at the index open abdomen coupled with mesh-mediated tractions offers the best outcome.
   Summary
   The key to optimizing outcome is early abdominal closure within 7 days because failure to do so will increase morbidity, mortality and fistulae formation. Novel techniques complementing existing de-resuscitation techniques are discussed.
C1 [Sugrue, Michael] Letterkenny Univ Hosp, Donegal Clin Res Acad Ireland, Dept Surg, Donegal, Ireland.
RP Sugrue, M (通讯作者)，Letterkenny Univ Hosp, Kilmacrennan Rd, Letterkenny, Ireland.
EM acstrauma@hotmail.com
CR [Anonymous], 2016, Emergency surgery performance, quality and outcome consensus summit-resource for optimal care of emergency surgery
   Atema JJ, 2015, WORLD J SURG, V39, P912, DOI 10.1007/s00268-014-2883-6
   Balogh Z, 2004, AM J SURG, V188, P679, DOI 10.1016/j.amjsurg.2004.08.052
   Bruns BR, 2016, J TRAUMA ACUTE CARE, V80, P631, DOI 10.1097/TA.0000000000000958
   Cheatham ML, 2010, CRIT CARE MED, V38, P402, DOI 10.1097/CCM.0b013e3181b9e9b1
   Cheatham ML, 2000, J TRAUMA, V49, P621, DOI 10.1097/00005373-200010000-00008
   Coccolini F, 2015, WORLD J EMERG SURG, V10, DOI 10.1186/s13017-015-0029-2
   Cothren CC, 2006, AM J SURG, V192, P238, DOI 10.1016/j.amjsurg.2006.04.010
   Dennis AJ, 2015, PLAST RECONSTR SURG, V135, P1113, DOI 10.1097/PRS.0000000000001057
   FIETSAM R, 1989, AM SURGEON, V55, P396
   Frazee RC, 2013, J AM COLL SURGEONS, V216, P730, DOI 10.1016/j.jamcollsurg.2012.12.035
   Harvin JA, 2013, J TRAUMA ACUTE CARE, V74, P426, DOI 10.1097/TA.0b013e31827e2a96
   Ivatury RR, 1998, J TRAUMA, V44, P1016, DOI 10.1097/00005373-199806000-00014
   Khan A, 2013, J TRAUMA ACUTE CARE, V75, P365, DOI 10.1097/TA.0b013e31829cb65e
   Kirkpatrick AW, 2015, ANN SURG, V262, P38, DOI 10.1097/SLA.0000000000001095
   Kirkpatrick AW, 2016, SCAND J SURG
   Lambertz A, 2015, INT J SURG, V13, P12, DOI 10.1016/j.ijsu.2014.11.025
   Malbrain MLNG, 2006, INTENS CARE MED, V32, P1722, DOI 10.1007/s00134-006-0349-5
   Malbrain ML, 2009, INT J INTENSIVE CARE, V56, P19
   Mason SA, 2016, ANN SURG, V264, P1142, DOI 10.1097/SLA.0000000000001615
   Mentula P, 2010, ARCH SURG-CHICAGO, V145, P764, DOI 10.1001/archsurg.2010.132
   Miller PR, 2004, ANN SURG, V239, P608, DOI 10.1097/01.sla.0000124291.09032.bf
   Petersson U, 2007, WORLD J SURG, V31, P2133, DOI 10.1007/s00268-007-9222-0
   Smit M, 2016, WORLD J SURG, V40, P1454, DOI 10.1007/s00268-015-3388-7
   Smith JW, 2014, J TRAUMA ACUTE CARE, V77, P393, DOI 10.1097/TA.0000000000000393
   Stawicki SP, 2008, INJURY, V39, P93, DOI 10.1016/j.injury.2007.06.011
   Sturini E, 2008, INTENS CARE MED, V34, P1632, DOI 10.1007/s00134-008-1155-z
   Sugrue M, 1999, ARCH SURG-CHICAGO, V134, P1082, DOI 10.1001/archsurg.134.10.1082
   SUGRUE M, 1995, BJS-BRIT J SURG, V82, P235, DOI 10.1002/bjs.1800820234
   Sugrue M, 2002, WORLD J SURG, V26, P1428, DOI 10.1007/s00268-002-6411-8
NR 30
TC 19
Z9 23
U1 0
U2 5
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1070-5295
EI 1531-7072
J9 CURR OPIN CRIT CARE
JI Curr. Opin. Crit. Care
PD FEB
PY 2017
VL 23
IS 1
BP 73
EP 78
DI 10.1097/MCC.0000000000000371
PG 6
WC Critical Care Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC General & Internal Medicine
GA EH7LM
UT WOS:000391954500012
PM 27941356
DA 2026-07-24
ER

PT J
AU Sabapathy, SR
   del Piñal, F
   Boyer, MI
   Lee, DC
   Sebastin, SJ
   Venkatramani, H
AF Sabapathy, S. Raja
   del Pinal, Francisco
   Boyer, Martin I.
   Lee, Dong Chul
   Sebastin, Sandeep Jacob
   Venkatramani, Hari
TI Management of a mutilated hand: the current trends
SO JOURNAL OF HAND SURGERY-EUROPEAN VOLUME
LA English
DT Review
DE Mutilated hand; mangled extremity; microsurgical hand reconstruction;
   limb salvage
ID UPPER EXTREMITY; MICROSURGICAL RECONSTRUCTION; OPEN FRACTURES; INJURIES;
   DEBRIDEMENT; FLAP; CLASSIFICATION; REEVALUATION; GUIDELINES; OUTCOMES
AB Mutilated upper limbs suffer loss of substance of various tissues with loss of prehension. The most important factor in salvage of a mutilated hand is involvement of a senior surgeon at the time of initial assessment and debridement. A regional block given on arrival helps through assessment and investigations in a pain-free state. Infection still remains the important negative determinant to outcome and is prevented by emergent radical debridement and early soft tissue cover. Radical debridement and secure skeletal stabilization must be achieved on day one in all situations. Dermal substitutes and negative pressure wound therapy are increasingly used but have not substituted regular soft tissue cover techniques. Ability to perform secondary procedures and the increased use of the reconstructed hand with time keeps reconstruction a better option than prosthesis fitting. Toe transfers and free functioning muscle transfers are the two major secondary procedures that have influenced outcomes.
C1 [Sabapathy, S. Raja; Venkatramani, Hari] Ganga Hosp, Dept Plast Hand & Microsurg & Burns, 313 Mettupalayam Rd, Coimbatore 641043, Tamil Nadu, India.
   [Boyer, Martin I.] Washington Univ, Sch Med, Orthopaed Surg, St Louis, MO USA.
   [Lee, Dong Chul] Gwangmyeong Sungae Gen Hosp, Plast & Reconstruct Surg & Hand Surg, Gyeonggi Do, South Korea.
   [Sebastin, Sandeep Jacob] Natl Univ Hlth Syst, Hand & Reconstruct Microsurg, Singapore, Singapore.
C3 Washington University (WUSTL); National University of Singapore
RP Sabapathy, SR (通讯作者)，Ganga Hosp, Dept Plast Hand & Microsurg & Burns, 313 Mettupalayam Rd, Coimbatore 641043, Tamil Nadu, India.
EM rajahand@gmail.com
RI Sabapathy, S Raja/AAL-5420-2020; /E-7820-2010; /AAD-2455-2019; del
   PIñal, Francisco/IUN-5005-2023
OI Sabapathy, S Raja/0000-0002-0456-8555; 
CR Ali B, 2020, PRS-GLOB OPEN, V8, DOI 10.1097/GOX.0000000000002965
   Baltzer HL, 2016, HAND CLIN, V32, P443, DOI 10.1016/j.hcl.2016.07.003
   Campbell DA, 1996, J HAND SURG-BRIT EUR, V21B, P295, DOI 10.1016/S0266-7681(05)80187-1
   Chan J, 2004, AM J OCCUP THER, V58, P128, DOI 10.5014/ajot.58.2.128
   Del Piñal F, 2006, J HAND SURG-BRIT EUR, V31B, P588, DOI 10.1016/j.jhsb.2006.07.009
   del Piñal F, 2007, J PLAST RECONSTR AES, V60, P816, DOI 10.1016/j.bjps.2007.02.019
   del Piñal F, 2006, J HAND SURG-AM, V31A, P1075, DOI 10.1016/j.jhsa.2006.03.021
   del Piñal F, 2020, CLIN PLAST SURG, V47, P461, DOI 10.1016/j.cps.2020.06.003
   Devendra A, 2019, J BONE JOINT SURG AM, V101, DOI 10.2106/JBJS.18.01235
   Foo A, 2016, HAND CLIN, V32, P555, DOI 10.1016/j.hcl.2016.07.006
   Foote CJ, 2021, J BONE JOINT SURG AM, V103, P265, DOI 10.2106/JBJS.20.01103
   Giladi AM, 2017, WORLD J SURG, V41, P1420, DOI 10.1007/s00268-017-3902-1
   Giladi AM, 2016, HAND CLIN, V32, P465, DOI 10.1016/j.hcl.2016.06.002
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   Heckmann N, 2020, JBJS REV, V8, DOI 10.2106/JBJS.RVW.19.00061
   Ketonis Constantinos, 2017, Hand (N Y), V12, P119, DOI [10.1177/1558944716643294, 10.1177/1558944716643294]
   Kovacs L, 2011, J PLAST RECONSTR AES, V64, P1495, DOI 10.1016/j.bjps.2011.05.022
   Kusnezov N, 2015, ORTHOP SURG, V7, P306, DOI 10.1111/os.12213
   Lee DC, 2019, HAND CLIN, V35, P185, DOI 10.1016/j.hcl.2019.01.001
   Meyer TM, 2003, HAND CLIN, V19, P41, DOI 10.1016/S0749-0712(02)00056-2
   Ng ZY, 2015, SEMIN PLAST SURG, V29, P48, DOI 10.1055/s-0035-1544170
   Sabapathy SR, 2008, J HAND SURG-EUR VOL, V33E, P65, DOI 10.1177/1753193407087868
   Sabapathy SR, 2020, PRS-GLOB OPEN, V8, DOI 10.1097/GOX.0000000000003191
   Sabapathy SR, 2016, HAND CLIN, V32, P585, DOI 10.1016/j.hcl.2016.06.003
   Sabapathy SR, 2013, SEMIN PLAST SURG, V27, P198, DOI 10.1055/s-0033-1360587
   Sabapathy SR, 2013, INJURY, V44, P370, DOI 10.1016/j.injury.2013.01.012
   Salminger S, 2022, DISABIL REHABIL, V44, P3708, DOI 10.1080/09638288.2020.1866684
   Schottel PC, 2021, J BONE JOINT SURG AM, V103, DOI 10.2106/JBJS.20.01604
   Tubinana, 1984, MUTILATING INJURIES
   Venkatramani H, 2019, INJURY, V50, pS105, DOI 10.1016/j.injury.2019.10.059
   Venkatramani H, 2019, J PLAST RECONSTR AES, V72, P529, DOI 10.1016/j.bjps.2019.01.022
   Warrender WJ, 2018, HAND CLIN, V34, P9, DOI 10.1016/j.hcl.2017.09.001
   WEI FC, 1993, BRIT J PLAST SURG, V46, P181
   Wei FC, 2018, PLAST RECONSTR SURG, V141, P128, DOI 10.1097/PRS.0000000000003940
   Weinzweig J, 1997, PLAST RECONSTR SURG, V100, P1200, DOI 10.1097/00006534-199710000-00020
NR 35
TC 6
Z9 10
U1 0
U2 3
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1753-1934
EI 2043-6289
J9 J HAND SURG-EUR VOL
JI J. Hand Surg.-Eur. Vol.
PD JAN
PY 2022
VL 47
IS 1
BP 98
EP 104
AR 17531934211047760
DI 10.1177/17531934211047760
EA OCT 2021
PG 7
WC Orthopedics; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics; Surgery
GA XV5CM
UT WOS:000707831600001
PM 34632847
DA 2026-07-24
ER

PT J
AU Vieira, ALG
   Stocco, JGD
   Ribeiro, ACG
   Frantz, CV
AF Gomide Vieira, Ana Laura
   Dorociaki Stocco, Janislei Giseli
   Gaspar Ribeiro, Anna Carolina
   Frantz, Cristina Valeria
TI Dressings used to prevent surgical site infection in the postoperative
   period of cardiac surgery: integrative review
SO REVISTA DA ESCOLA DE ENFERMAGEM DA USP
LA English
DT Review
DE Cardiovascular Nursing; Thoracic Surgery; Surgical Wound Infection;
   Review
ID WOUND INFECTIONS; CLINICAL-TRIAL; QUALITY; CARE
AB Objective: To identify and describe which dressings are recommended to prevent surgical site infection in hospitalized adult patients after cardiac surgeries. Method: Integrative review carried out in the databases MEDLINE, LILACS, CINAHL, Web of Science, Cochrane and Scopus. Studies related to dressing in the postoperative period of cardiac surgery were selected. Results: Seven articles were included, with the following dressings: negative pressure wound therapy, silver nylon dressing, transdermal delivery of continuous oxygen and impermeable adhesive drape. The dressings that led to reduction of infection were negative pressure and silver nylon dressings. Conclusion: It was not possible to identify which dressing is most recommended, however, some studies show that certain types of dressings were related to the reduction of infection. Clinical trials with a rigorous methodological design and representative samples able to minimize the risk of bias should be conducted to evaluate the effectiveness of dressings in the prevention of surgical site infection.
C1 [Gomide Vieira, Ana Laura; Frantz, Cristina Valeria] Univ Fed Parana, Hosp Clin, Programa Residencia Integrada Multiprofiss Atenca, Curitiba, PR, Brazil.
   [Dorociaki Stocco, Janislei Giseli] Univ Fed Parana, Hosp Clin, Serv Controle Infeccao Hosp, Curitiba, PR, Brazil.
   [Gaspar Ribeiro, Anna Carolina] Univ Fed Parana, Hosp Clin, Ctr Terapia Intens Cardiol, Curitiba, PR, Brazil.
C3 Universidade Federal do Parana; Universidade Federal do Parana;
   Universidade Federal do Parana
RP Vieira, ALG (通讯作者)，Rua Gen Carneiro,181 Bairro Alto Gloria, BR-80060900 Curitiba, PR, Brazil.
EM analaura.gov@gmail.com
OI Gaspar Ribeiro, Anna Carolina/0000-0002-8523-7634
CR [Anonymous], 2016, GLOBAL GUIDELINES PR, P186
   [Anonymous], REL DES HUM 2015
   Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Santos APA, 2016, REV ESC ENFERM USP, V50, P472, DOI 10.1590/S0080-623420160000400014
   Bakri MH, 2008, ANESTH ANALG, V106, P1619, DOI 10.1213/ane.0b013e3181732e82
   Biancari F, 2010, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008057.pub2
   Boateng JS, 2008, J PHARM SCI-US, V97, P2892, DOI 10.1002/jps.21210
   Brasil. Ministerio da Saude; Secretaria de Ciencia Tecnologia e Insumos Estrategicos Departamento de Ciencia e Tecnologia, 2014, DIR MET EL REV SIST
   British Medical Association and Royal Pharmaceutical Society of Great Britain, 2011, BRIT NATL FORMULARY
   Center for Evidence Based Medicine, 2011, OCEBM LEV EV
   Colli A, 2011, J CARDIOTHORAC SURG, V6, DOI 10.1186/1749-8090-6-160
   De Feo M, 2001, ANN THORAC SURG, V71, P324, DOI 10.1016/S0003-4975(00)02137-8
   Downie Fiona, 2010, Br J Nurs, V19, pS42
   GANONG LH, 1987, RES NURS HEALTH, V10, P1, DOI 10.1002/nur.4770100103
   Gelape Cláudio Léo, 2007, Arq. Bras. Cardiol., V89, pe3
   da Silva QCG, 2012, ACTA PAUL ENFERM, V25, P89, DOI 10.1590/S0103-21002012000900014
   Graf K, 2010, EUR J CARDIO-THORAC, V37, P893, DOI 10.1016/j.ejcts.2009.10.005
   Grauhan O, 2014, INT WOUND J, V11, P6, DOI 10.1111/iwj.12294
   Grauhan O, 2013, J THORAC CARDIOV SUR, V145, P1387, DOI 10.1016/j.jtcvs.2012.09.040
   Guyatt GH, 2011, J CLIN EPIDEMIOL, V64, P1311, DOI [10.1016/j.jclinepi.2011.06.004, 10.1016/j.jclinepi.2011.03.017]
   Higgins J., 2011, COCHRANE COLLABORATI, DOI [DOI 10.2105/AJPH.2020.305609, DOI 10.1002/14651858.CD001930.PUB3]
   Huckfeldt R, 2008, OSTOMY WOUND MANAG, V54, P36
   Hulley SB., 2008, Delineando a pesquisa clinica: uma abordagem epidemiologica
   Jadad AR, 1996, CONTROL CLIN TRIALS, V17, P1, DOI 10.1016/0197-2456(95)00134-4
   Malta DC, 2014, CIENC SAUDE COLETIVA, V19, P4, DOI 10.1590/1413-81232014191.0084
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Musallam E, 2014, J VASC NURS, V32, P105, DOI 10.1016/j.jvn.2014.01.003
   National Institute for Health and Care Excellence, 2013, SURG SIT INF PREV TR
   National Institute for Health and Care Excellence (NICE), 2020, Surgical Site Infections: Prevention and Treatment: NG125
   Nonin EAPM, 2008, REV LAT-AM ENFERM, V16, P57, DOI 10.1590/S0104-11692008000100010
   Pivoto FL, 2010, ACTA PAUL ENFERM, V23, P665, DOI 10.1590/S0103-21002010000500013
   Segers P, 2007, WOUND REPAIR REGEN, V15, P192, DOI 10.1111/j.1524-475X.2007.00204.x
   Ubbink DT, 2008, ARCH SURG-CHICAGO, V143, P950, DOI 10.1001/archsurg.143.10.950
   Wells GA., 2020, NEWCASTLE OTTAWA SCA
   World Health Organization. Media Centre, 2014, TOP 10 CAUS DEATH
NR 35
TC 11
Z9 14
U1 0
U2 11
PU UNIV SAO PAOLO
PI CERQUERA CESAR
PA AV  DR ENEAS DE CARVALHO AGUIAR, 419, CERQUERA CESAR, SP 05403-000,
   BRAZIL
SN 0080-6234
EI 1980-220X
J9 REV ESC ENFERM USP
JI Rev. Esc. Enferm. USP
PY 2018
VL 52
AR e03393
DI 10.1590/S1980-220X2017011803393
PG 9
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA HD3TG
UT WOS:000452442700001
PM 30517290
OA Green Submitted, Green Published, gold
DA 2026-07-24
ER

PT J
AU Endo, J
   Kuniyoshi, K
   Mochizuki, M
   Shimoyama, K
   Koyama, T
   Aiba, A
   Kadota, R
   Sasaki, Y
AF Endo, Jun
   Kuniyoshi, Kazuki
   Mochizuki, Makondo
   Shimoyama, Katsuhito
   Koyama, Tadaaki
   Aiba, Atsuomi
   Kadota, Ryo
   Sasaki, Yasuhito
TI Two-staged hindfoot reconstruction with vascularized fibula graft for
   calcaneal osteomyelitis caused by methicillin-resistant Staphylococcus
   aureus: A case report
SO MICROSURGERY
LA English
DT Article
ID FRACTURES
AB Hindfoot reconstruction after calcaneal osteomyelitis is a challenging procedure designed to restore the weight bearing function of the heel and to allow a functional reconstruction of the Achilles tendon. Some patients require subtalar arthrodesis after primary calcaneal osteosyntesis or hindfoot reconstruction due to the considerable pain associated with weight-bearing caused by the irregular surface of the subtalar joint. To date, no reports have shown a case of hindfoot reconstruction with subtalar arthrodesis using a pedicled vascularized fibula graft. We report a case of a 24-year-old woman who presented with calcaneal methicillin-resistant Staphylococcus aureus osteomyelitis after open comminuted fracture due to a fall. Radical debridement of bone and soft tissue was repeated six times in combination with negative pressure wound therapy, followed by hindfoot reconstruction with pedicled vascularized fibula and subtalar arthrodesis. Good functional restoration had been achieved by the final follow-up 18 months after surgery. (c) 2013 Wiley Periodicals, Inc. Microsurgery, 2013.
C1 [Endo, Jun; Kuniyoshi, Kazuki; Mochizuki, Makondo; Shimoyama, Katsuhito; Koyama, Tadaaki; Aiba, Atsuomi; Kadota, Ryo; Sasaki, Yasuhito] Numazu City Hosp, Dept Orthopaed Surg, Shizuoka 4100302, Japan.
RP Endo, J (通讯作者)，Numazu City Hosp, 550 Higashi Shiiji, Shizuoka 4100302, Japan.
EM orthopaedics@hotmail.co.jp
CR Attinger C, 2001, ORTHOP CLIN N AM, V32, P135, DOI 10.1016/S0030-5898(05)70199-1
   Baumhauer JF, 1998, FOOT ANKLE INT, V19, P849, DOI 10.1177/107110079801901210
   Brenner P, 2000, J TRAUMA, V49, P331, DOI 10.1097/00005373-200008000-00023
   Cai JF, 1997, PLAST RECONSTR SURG, V99, P448, DOI 10.1097/00006534-199702000-00020
   Cierny III G., 2006, J AM ACAD ORTHOP SUR, V14, P105
   CRANDALL RC, 1981, J BONE JOINT SURG AM, V63, P152, DOI 10.2106/00004623-198163010-00020
   Damiani G, 2011, J PLAST RECONSTR AES, V64, P1119, DOI 10.1016/j.bjps.2010.11.022
   Eid MAM, 2010, STRATEG TRAUMA LIMB, V5, P39, DOI 10.1007/s11751-010-0081-0
   Korompilias AV, 2011, MICROSURG, V31, P171, DOI 10.1002/micr.20848
   Kurvin L A, 2008, Foot Ankle Surg, V14, P221, DOI 10.1016/j.fas.2008.03.004
   Maurer-Ertl W, 2012, MICROSURG, V32, P364, DOI 10.1002/micr.21959
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Ortak Turgut, 2005, J Foot Ankle Surg, V44, P265, DOI 10.1053/j.jfas.2005.04.001
   Papagelopoulos PJ, 2006, J INT MED RES, V34, P704, DOI 10.1177/147323000603400618
   Potenza V, 2010, INJURY, V41, P702, DOI 10.1016/j.injury.2009.12.002
   Scoccianti G, 2009, FOOT ANKLE INT, V30, P716, DOI 10.3113/FAI.2009.0716
   Wiersema B, 2011, FOOT ANKLE INT, V32, P1052, DOI 10.3113/FAI.2011.1052
NR 17
TC 10
Z9 16
U1 0
U2 3
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0738-1085
J9 MICROSURG
JI Microsurgery
PD MAR
PY 2013
VL 33
IS 3
BP 232
EP 235
DI 10.1002/micr.22070
PG 4
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 108ZR
UT WOS:000316335400011
PM 23345037
DA 2026-07-24
ER

PT J
AU Hawthorne, B
   Simmons, JK
   Stuart, B
   Tung, R
   Zamierowski, DS
   Mellott, AJ
AF Hawthorne, Briauna
   Simmons, J. Kai
   Stuart, Braden
   Tung, Robert
   Zamierowski, David S.
   Mellott, Adam J.
TI Enhancing wound healing dressing development through interdisciplinary
   collaboration
SO JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
LA English
DT Review
DE biomedical engineering; interdisciplinary teams; negative pressure wound
   therapy; wound dressings; wound healing
ID IN-VITRO; HYDROGEL; SCAFFOLDS; THERAPY; CLOSURE; REPAIR; BURNS
AB The process of wound healing includes four phases: Hemostasis, inflammation, proliferation, and remodeling. Many wound dressings and technologies have been developed to enhance the body's ability to close wounds and restore the function of damaged tissues. Several advancements in wound healing technology have resulted from innovative experiments by individual scientists or physicians working independently. The interplay between the medical and scientific research fields is vital to translating new discoveries in the lab to treatments at the bedside. Tracing the history of wound dressing development reveals that there is an opportunity for deeper collaboration between multiple disciplines to accelerate the advancement of novel wound healing technologies. In this review, we explore the different types of wound dressings and biomaterials used to treat wounds, and we investigate the role of multidisciplinary collaboration in the development of various wound management technologies to illustrate the benefit of direct collaboration between physicians and scientists.
C1 [Hawthorne, Briauna; Simmons, J. Kai; Stuart, Braden; Tung, Robert; Zamierowski, David S.; Mellott, Adam J.] Univ Kansas, Dept Plast Surg, Med Ctr, Mail Stop 3051 3901 Rainbow Blvd, Kansas City, KS 66160 USA.
C3 University of Kansas; University of Kansas Medical Center
RP Mellott, AJ (通讯作者)，Univ Kansas, Dept Plast Surg, Med Ctr, Mail Stop 3051 3901 Rainbow Blvd, Kansas City, KS 66160 USA.
EM amellott@kumc.edu
RI Mellott, AJ/HOF-9580-2023
OI Mellott, AJ/0000-0002-7545-3763
FU R3 lab
FX Authors would like to sincerely thank the entire R3 lab for their
   support, feedback, and encouragement.
CR Abulyazid I, 2013, ARAB J CHEM, V6, P265, DOI 10.1016/j.arabjc.2010.10.005
   Abzug MJ., 2018, CURRENT DIAGNOSIS TR, V24e
   Aderibigbe BA, 2018, PHARMACEUTICS, V10, DOI 10.3390/pharmaceutics10020042
   Agarwal A, 2011, WOODHEAD PUBL MATER, P186
   ALLEN KL, 1991, J PHARM PHARMACOL, V43, P817, DOI 10.1111/j.2042-7158.1991.tb03186.x
   Alves MH, 2011, MACROMOL BIOSCI, V11, P1293, DOI 10.1002/mabi.201100145
   Andrade Sabrina Meireles de, 2016, Rev Gaucha Enferm, V37, pe59257, DOI 10.1590/1983-1447.2016.02.59257
   Aramwit P, 2016, WOODH PUBL SER BIOM, V115, P3, DOI 10.1016/B978-1-78242-456-7.00001-5
   Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   ARTANDI C, 1977, RADIAT PHYS CHEM, V9, P183, DOI 10.1016/0146-5724(77)90078-4
   Artandi C, 1972, Int Anesthesiol Clin, V10, P123, DOI 10.1097/00004311-197201020-00011
   ARTANDI C, 1964, Bull Parenter Drug Assoc, V18, P2
   ARTANDI C, 1960, NUCL INSTRUM METHODS, V6, P279, DOI 10.1016/0029-554X(59)90135-1
   Artandi C., 1958, NUCLEONICS, V16, P118
   AULT GW, 1949, AM J SURG, V77, P352, DOI 10.1016/0002-9610(49)90163-4
   Baum CL, 2005, DERMATOL SURG, V31, P674
   Bencherif SA, 2012, P NATL ACAD SCI USA, V109, P19590, DOI 10.1073/pnas.1211516109
   Bhattarai S, 2011, PHARM DEV TECHNOL, V16, P259, DOI 10.3109/10837451003664073
   Billiar TR., 2019, SCHWARTZS PRINCIPLES, V11e
   Billiar TR., 2019, SCHWARTZS PRINCIPLES, V11e
   Bourdillon KA, 2017, INT WOUND J, V14, P1066, DOI 10.1111/iwj.12761
   Boyle, 2007, WOUND DRESSINGS COMP
   Broughton G, 2006, PLAST RECONSTR SURG, V117, p12S, DOI 10.1097/01.prs.0000225430.42531.c2
   Broussard KC, 2013, AM J CLIN DERMATOL, V14, P449, DOI 10.1007/s40257-013-0046-4
   Bunn HF., 2016, PATHOPHYSIOLOGY BLOO, V2e
   Burkitt HG., 2007, Essential Surgery: problems, diagnosis and management, V4th
   Butcher Gillian, 2013, Br J Nurs, V22, pS38
   Caskey, 2010, USE HONEY DRESSINGS
   Cerroni, DERMATOLOGY ONLINE R
   Chaby G, 2007, ARCH DERMATOL, V143, P1297, DOI 10.1001/archderm.143.10.1297
   Chang YJR, 2017, PLAST SURG-CHIR PLAS, V25, P21, DOI 10.1177/2292550317693813
   Charles, 1964, ETHICON INC ASSIGNEE
   Childs DR, 2017, SURG CLIN N AM, V97, P189, DOI 10.1016/j.suc.2016.08.013
   Choe G, 2018, POLYMERS-BASEL, V10, DOI 10.3390/polym10090997
   Cullen B, 2002, WOUND REPAIR REGEN, V10, P16, DOI 10.1046/j.1524-475X.2002.10703.x
   Cullen B, 2002, INT J BIOCHEM CELL B, V34, P1544, DOI 10.1016/S1357-2725(02)00054-7
   Cullen Breda, 2002, Ostomy Wound Manage, V48, P8
   Cullen BM, 2017, ADV SKIN WOUND CARE, V30, P464, DOI 10.1097/01.ASW.0000524452.80170.d8
   DESMET G, 2017, PLAST RECONSTR SURG, V25, P591
   Dhanraj P, 2015, INDIAN J SURG, V77, pS385, DOI 10.1007/s12262-013-0850-3
   Dhivya S, 2015, BIOMEDICINE-TAIWAN, V5, P24, DOI 10.7603/s40681-015-0022-9
   Dow, 1972, ADHESIVE MAT
   Du Vigneaud V, 1935, P SOC EXP BIOL MED, V33, P371
   du Vigneaud V, 1937, J BIOL CHEM, V117, P589
   E HM; T.J. SMITH  NEPHEW LTD, 1972, MOISTURE VAPOR PERME
   Ellis S, 2018, CURR DERMATOL REP, V7, P350, DOI 10.1007/s13671-018-0234-9
   Eming S.A., 2012, Dermatology
   Errede LANO., 1983, MINNESOTA MINING MAN
   Finch, ANTIBIOTIC CHEMOTHER
   Fischer J., SEEING NURSES NEED S
   Frantz VK, 1944, ANN SURG, V120, P181
   Gantwerker EA, 2011, FACIAL PLAST SURG CL, V19, P441, DOI 10.1016/j.fsc.2011.06.009
   Ghadi R, 2016, WOODH PUBL SER BIOM, V115, P203, DOI 10.1016/B978-1-78242-456-7.00010-6
   Glass GE, 2012, J PLAST RECONSTR AES, V65, P989, DOI 10.1016/j.bjps.2011.12.012
   GOLDSTEIN AE, 1948, J UROLOGY, V59, P195, DOI 10.1016/S0022-5347(17)69362-5
   Gottrup F, 2013, WOUND REPAIR REGEN, V21, P216, DOI 10.1111/wrr.12020
   Guo S, 2010, J DENT RES, V89, P219, DOI 10.1177/0022034509359125
   Gurtner G C., 2017, Plastic surgery E-book: volume 1 principles
   Gwak JH, 2017, PLOS ONE, V12, DOI 10.1371/journal.pone.0174203
   Habashy RR, 2005, PHARMACOL RES, V51, P95, DOI 10.1016/j.phrs.2004.04.011
   Hadley, 2013, SILICONE GEL COATED
   Hamm RL., 2019, TEXT ATLAS WOUND DIA, V2e
   Harris JF, 2013, SERPENTINE WALL: THE WINDING BOUNDARY BETWEEN CHURCH AND STATE IN THE UNITED STATES, P1
   Hart J, 2002, INT J BIOCHEM CELL B, V34, P1557, DOI 10.1016/S1357-2725(02)00062-6
   HATCH WE, 1948, J UROLOGY, V59, P887, DOI 10.1016/S0022-5347(17)69455-2
   Heinecke SB., 1985, 3M ASSIGNEE DEVICE M
   Hepburn C., 1982, POLYURETHANE ELASTOM
   HINMAN F, 1949, SURGERY, V26, P633
   Huang Y, 2005, BIOMATERIALS, V26, P7616, DOI 10.1016/j.biomaterials.2005.05.036
   Huang Y, 2020, CHEM MATER, V32, P6595, DOI 10.1021/acs.chemmater.0c02030
   Iserson KV., 2016, IMPROVISED MED PROVI, V2e
   Jaffe L, 2019, CLIN PODIATR MED SUR, V36, P397, DOI 10.1016/j.cpm.2019.02.005
   JAMES JH, 1975, BRIT J PLAST SURG, V28, P107, DOI 10.1016/S0007-1226(75)90169-1
   Jayakumar R, 2011, BIOTECHNOL ADV, V29, P322, DOI 10.1016/j.biotechadv.2011.01.005
   Johnson A, 1989, Nurs Stand, V3, P8, DOI 10.7748/ns.3.40.8.s73
   Jones V, 2006, BMJ-BRIT MED J, V332, P777, DOI 10.1136/bmj.332.7544.777
   Kamoun EA, 2017, J ADV RES, V8, P217, DOI 10.1016/j.jare.2017.01.005
   KANNON GA, 1995, DERMATOL SURG, V21, P583, DOI 10.1111/j.1524-4725.1995.tb00511.x
   Kenyon, 1941, EASTMAN KODAK COASSI
   Khan I, 2015, ADV WOUND CARE, V4, P724, DOI 10.1089/wound.2014.0623
   Krystel-Whittemore M, 2016, FRONT IMMUNOL, V6, P1, DOI 10.3389/fimmu.2015.00620
   Krzyszczyk P, 2018, FRONT PHYSIOL, V9, DOI 10.3389/fphys.2018.00419
   Kumar V., 2010, ROBBINS COTRAN PATHO
   Lakshmi DS, 2017, CARBOHYD POLYM, V157, P1604, DOI 10.1016/j.carbpol.2016.11.042
   Landriscina A, 2015, J DRUGS DERMATOL, V14, P92
   Larking AM, 2010, CLIN REHABIL, V24, P222, DOI 10.1177/0269215509346083
   LAURENT TC, 1992, FASEB J, V6, P2397, DOI 10.1096/fasebj.6.7.1563592
   Lecomte, 2018, WOUND DRESSING METHO
   Lee KY, 2012, PROG POLYM SCI, V37, P106, DOI 10.1016/j.progpolymsci.2011.06.003
   Lee S, 2016, INT J BIOL MACROMOL, V83, P1, DOI 10.1016/j.ijbiomac.2015.11.050
   Levinson W., 2020, REV MED MICROBIOLOGY, V16
   Li J, 2003, BIOMACROMOLECULES, V4, P1055, DOI 10.1021/bm034069l
   Li M, 2020, CHEM MATER, V32, P9937, DOI 10.1021/acs.chemmater.0c02823
   Liang YP, 2019, SMALL, V15, DOI 10.1002/smll.201900046
   Long JJJ, 2019, MAT SCI ENG C-MATER, V104, DOI 10.1016/j.msec.2019.109873
   Longinotti C, 2014, BURNS TRAUMA, V2, DOI 10.4103/2321-3868.142398
   Madihally SV, 2010, ENG MED BIOL, P1
   Marchese A, 2016, FOOD CHEM, V210, P402, DOI 10.1016/j.foodchem.2016.04.111
   Mellott Adam J, 2016, Dent J (Basel), V4, DOI [10.3390/dj4030030, 10.3390/dj4030030]
   Mero A, 2014, POLYMERS-BASEL, V6, P346, DOI 10.3390/polym6020346
   Miller, BASICS ANESTHESIA ON
   Mir M, 2018, PROG BIOMATER, V7, P1, DOI 10.1007/s40204-018-0083-4
   Mishra R.K., 2012, Asian Journal of Pharmaceutical and Clinical Research, V5, P1, DOI DOI 10.1002/9781118301234.CH1
   Mogosanu GD, 2014, INT J PHARMACEUT, V463, P127, DOI 10.1016/j.ijpharm.2013.12.015
   Molan, 2011, HONEY BASED WOUND DR
   Molan, 2005, HONEY BASED WOUND DR
   Molan P C, 2001, Am J Clin Dermatol, V2, P13, DOI 10.2165/00128071-200102010-00003
   Molan PC, 1996, J PHARM PHARMACOL, V48, P1206, DOI 10.1111/j.2042-7158.1996.tb03922.x
   Morykwas, 2007, WOUND TREATMENT EMPL
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mosca RC, 2019, ADV SKIN WOUND CARE, V32, P157, DOI 10.1097/01.ASW.0000553600.97572.d2
   Munarin F, 2012, INT J BIOL MACROMOL, V51, P681, DOI 10.1016/j.ijbiomac.2012.07.002
   Narayanaswamy R, 2019, MOLECULES, V24, DOI 10.3390/molecules24030603
   Neto, 2017, HONEY BASED FOAM COM
   Op't Veld RC, 2020, TISSUE ENG PART B-RE, V26, P230, DOI [10.1089/ten.TEB.2019.0281, 10.1089/ten.teb.2019.0281]
   OWENS N, 1946, SURGERY, V19, P482
   Pallaske F, 2018, J WOUND CARE, V27, P692, DOI 10.12968/jowc.2018.27.10.692
   Park JU, 2017, J BIOMED MATER RES B, V105, P1828, DOI 10.1002/jbm.b.33711
   Patel Sejal, 2001, Journal of Insect Science (Tucson), V1, P1
   Peerschke EIB, 2008, ADV EXP MED BIOL, V632, P81, DOI 10.1007/978-0-387-78952-1_7
   Peter Moloney, 2014, THERAPEUTIC COMPOSIT
   Pfenninger JL, 2010, Pfenninger and Fowler's Procedures for Primary Care, V3rd
   Pincus MR., ONLINE RESOURCE, Vxvii
   PONTEN B, 1976, SCAND J PLAST RECONS, V10, P237, DOI 10.3109/02844317609012975
   POSTMES T, 1995, EXPERIENTIA, V51, P986, DOI 10.1007/BF01921753
   Qu J, 2018, BIOMATERIALS, V183, P185, DOI 10.1016/j.biomaterials.2018.08.044
   Qureshi AA, 2011, PLAST RECONSTR SURG, V128, p721E, DOI 10.1097/PRS.0b013e318230c7d1
   Rabow MW., 2020, CURRENT MEDICAL DIAG
   Radha Maharjan H, 2015, J Tradit Complement Med, V5, P21, DOI 10.1016/j.jtcme.2014.10.006
   Rai D, 2008, BIOCHEM J, V410, P147, DOI 10.1042/BJ20070891
   Reinke JM, 2012, EUR SURG RES, V49, P35, DOI 10.1159/000339613
   Rice R., 2006, Home care nursing practice: concepts and application
   ROBERT W., JOHNSON ASSIGNEE SUR
   Scales JT., 1963, BRIT J IND MED, V20, p82
   Schmitt, 1952, ARMOUR COASSIGNEE SU
   Seaman S, 2002, J AM PODIAT MED ASSN, V92, P24, DOI 10.7547/87507315-92-1-24
   Shoulders MD, 2009, ANNU REV BIOCHEM, V78, P929, DOI 10.1146/annurev.biochem.77.032207.120833
   Sifferd R., 1936, VORKOMMEN STERINEN B, V239, P270
   Sifferd RH, 1934, P SOC EXP BIOL MED, V32, P332
   Simoes D, 2018, EUR J PHARM BIOPHARM, V127, P130, DOI 10.1016/j.ejpb.2018.02.022
   Singh R, 2017, INT WOUND J, V14, P1276, DOI 10.1111/iwj.12797
   Sionkowska A, 2011, PROG POLYM SCI, V36, P1254, DOI 10.1016/j.progpolymsci.2011.05.003
   Smith, 1964, HEMOSTATIC SURG DRES
   Smith, 1959, CELLULOSIC HEMOSTATI
   Smith AM, 2016, WOODH PUBL SER BIOM, V115, P261, DOI 10.1016/B978-1-78242-456-7.00013-1
   Smith P.J., 1976, Burns, V2, P254
   SNOW RS, 1975, BRIT J PLAST SURG, V28, P289, DOI 10.1016/0007-1226(75)90034-X
   Stranford SA., 2013, KUBY IMMUNOLOGY WH
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   SUBRAHMANYAM M, 1993, BRIT J PLAST SURG, V46, P322, DOI 10.1016/0007-1226(93)90012-Z
   Tan PWW, 2009, INT WOUND J, V6, P295, DOI 10.1111/j.1742-481X.2009.00611.x
   Teodorescu M, 2019, BIOTECHNOL ADV, V37, P109, DOI 10.1016/j.biotechadv.2018.11.008
   Theilgaard-Mönch K, 2004, J IMMUNOL, V172, P7684, DOI 10.4049/jimmunol.172.12.7684
   Thom SR, 2011, PLAST RECONSTR SURG, V127, p131S, DOI 10.1097/PRS.0b013e3181fbe2bf
   Townsend, 1976, BURNS, V2, P82
   Trevor, 2019, KATZUNG TREVORS PHAR, V12e
   Truong B, 2016, CUREUS J MED SCIENCE, V8, DOI 10.7759/cureus.730
   Van Winkle Jr W., 1959, NUCLEONICS, V17, P86
   VANDERHOOF ES, 1949, ARCH SURG-CHICAGO, V58, P182, DOI 10.1001/archsurg.1949.01240030187005
   Veves A, 2002, ARCH SURG-CHICAGO, V137, P822, DOI 10.1001/archsurg.137.7.822
   Vowden K, 2017, Surgery (Oxford), V35, P489, DOI [10.1016/j.mpsur.2017.06.005, 10.1016/j.mpsur.2017.06.005, DOI 10.1016/J.MPSUR.2017.06.005]
   Wang PH, 2018, J CHIN MED ASSOC, V81, P94, DOI 10.1016/j.jcma.2017.11.002
   Wasiak Jason, 2015, BMJ Clin Evid, V2015
   Weidig HenryP., SURG DRESSING
   Weil PA., 2018, HARPERS ILLUSTRATED, V31e
   Weller Carolina., 2006, J PHARM PRACT RES, V36, P318, DOI DOI 10.1002/J.2055-2335.2006.TB00640.X
   WINTER G, 1962, BRIT J IND MED, V193, P293
   WINTER GD, 1974, J BIOMED MATER RES, V8, P99, DOI 10.1002/jbm.820080311
   WINTER GD, 1975, PLAST RECONSTR SURG, V56, P531, DOI 10.1097/00006534-197511000-00009
   Wood B, 1997, NEW ZEAL MED J, V110, P107
   Wu S, 2017, ADV SKIN WOUND CARE, V30, pS1, DOI 10.1097/01.ASW.0000525951.20270.6c
   Yan H, 2012, BURNS, V38, P877, DOI 10.1016/j.burns.2012.02.001
   Yang Z, 2016, BIOMACROMOLECULES, V17, P590, DOI 10.1021/acs.biomac.5b01538
   Yoo HJ, 2008, J BIOMED MATER RES B, V85B, P326, DOI 10.1002/jbm.b.30950
   Younes I, 2015, MAR DRUGS, V13, P1133, DOI 10.3390/md13031133
   Zagho MM, 2018, POLYMERS-BASEL, V10, DOI 10.3390/polym10070739
   Zamierowski DavidS., 2005, TISSUE CLOSURE TREAT
   Zhang BL, 2020, CHEM ENG J, V400, DOI 10.1016/j.cej.2020.125994
   Zhao X, 2021, CHEM ENG J, V403, DOI 10.1016/j.cej.2020.126329
   Zhao X, 2018, NAT COMMUN, V9, DOI 10.1038/s41467-018-04998-9
   Zhu JM, 2010, BIOMATERIALS, V31, P4639, DOI 10.1016/j.biomaterials.2010.02.044
NR 181
TC 61
Z9 72
U1 4
U2 78
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1552-4973
EI 1552-4981
J9 J BIOMED MATER RES B
JI J. Biomed. Mater. Res. Part B
PD DEC
PY 2021
VL 109
IS 12
BP 1967
EP 1985
DI 10.1002/jbm.b.34861
EA MAY 2021
PG 19
WC Engineering, Biomedical; Materials Science, Biomaterials
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Materials Science
GA WA7HX
UT WOS:000651299000001
PM 34002476
OA Green Submitted, hybrid
DA 2026-07-24
ER

PT J
AU Holford, NC
AF Holford, Nicholas Charles
TI Negative-pressure wound therapy - does it lower the risk of
   complications with closed wounds following breast surgery?
SO EXPERT REVIEW OF MEDICAL DEVICES
LA English
DT Article
DE Negative Pressure; pico; wound therapy; wound complications; breast
   surgery
ID RECONSTRUCTION
AB Introduction:Breast surgery complications are important not only due to their morbidity and psychological impact, but also the delays that can occur for adjuvant treatment or the loss of implants in severe cases. There is growing evidence that negative pressure dressing on closed wounds can reduce the complications following surgery.Methods:This study aimed to assess whether negative-pressure dressings reduced complications in patients undergoing bilateral reduction mammoplasty with randomization of a side to negative pressure and standard care, fixation strips, on the contralateral side. This allowed patients to act as their own controls.Results:This study found a significant reduction in the rate of wound complications but used a wide definition for what constituted a wound complication.Discussion:This finding is mirrored in existing work with studies showing that negative-pressure therapy is a cost-effective intervention. Further work is required to validate this finding and targeting those at highest risk may be preferential.
C1 [Holford, Nicholas Charles] Reading Hosp, Royal Berkshire NHS Fdn Trust, Breast Surg Dept, Reading, Berks, England.
C3 Royal Berkshire Hospital
RP Holford, NC (通讯作者)，Royal Berkshire NHS Trust, Breast Surg Dept, Reading RG1 5AN, Berks, England.
EM Nicholas.holford@doctors.org.uk
CR Ball KE, 2010, 5 DEC INT C HLTH CAR
   Erdmann-Sager J, 2018, PLAST RECONSTR SURG, V141, P271, DOI 10.1097/PRS.0000000000004016
   Ferrando PM, 2018, PRS-GLOB OPEN, V6, DOI 10.1097/GOX.0000000000001732
   Fischer JP, 2014, J PLAST SURG HAND SU, V48, P104, DOI 10.3109/2000656X.2013.819003
   Gabriel A, 2019, PLAST RECONSTR SURG, V143, p36S, DOI 10.1097/PRS.0000000000005311
   Goulding V., 2015, The Diabetic Foot Journal, V18, P75, DOI DOI 10.1288/00005537-196908000-00007
   Haubner F, 2012, RADIAT ONCOL, V7, DOI 10.1186/1748-717X-7-162
   Hillam JS, 2017, J PLAST RECONSTR AES, V70, P734, DOI 10.1016/j.bjps.2016.12.012
   Holt R, 2015, BRIT J HOSP MED, V76, P217, DOI 10.12968/hmed.2015.76.4.217
   Hyldig N, 2019, BJOG-INT J OBSTET GY, V126, P619, DOI 10.1111/1471-0528.15573
   Isik O, 2015, CHIRURGIA-BUCHAREST, V110, P457
   Jacobs S, 2009, J PLAST RECONSTR AES, V62, P1331, DOI 10.1016/j.bjps.2008.03.024
   Kim DY, 2016, PLAST RECONSTR SURG, V138, P558, DOI 10.1097/PRS.0000000000002431
   The MC, 2012, J AM COLL CLIN WOUND, V4
   Turner EJH, 2014, FUTURE ONCOL, V10, P1049, DOI 10.2217/fon.13.257
   Webster J, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009261.pub4
NR 16
TC 2
Z9 2
U1 0
U2 2
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND
SN 1743-4440
EI 1745-2422
J9 EXPERT REV MED DEVIC
JI Expert Rev. Med. Devices
PD OCT 2
PY 2020
VL 17
IS 10
BP 1017
EP 1019
DI 10.1080/17434440.2020.1828058
EA OCT 2020
PG 3
WC Engineering, Biomedical
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering
GA OZ8JZ
UT WOS:000579382700001
PM 32964756
DA 2026-07-24
ER

PT J
AU Bozkurt, B
   Tokac, M
   Dumlu, EG
   Yalcin, A
   Kilic, M
AF Bozkurt, B.
   Tokac, M.
   Dumlu, E. G.
   Yalcin, A.
   Kilic, M.
TI Our First Experience With Negative Pressure Incision Management System
   Implemented on the Clean Surgical Incision in the Renal Transplantation
   Recipient: A Case Report
SO TRANSPLANTATION PROCEEDINGS
LA English
DT Article
ID WOUND-HEALING COMPLICATIONS; KIDNEY-TRANSPLANTATION; THERAPY; SERIES
AB Multiple comorbidities and environmental factors increase the complications of incisional wounds in patients. It was demonstrated in previous prospective and randomized studies that negative pressure wound therapy (NPWT) reduced wound infection and other complications in clean, closed surgical incisions. In this case report, the Prevena incision management system was implemented on the clean, closed surgical incision of a 52-year-old female patient, who was given a renal transplantation from cadaver postoperatively in the operating theater. It was removed from the patient on the fifth day after the operation. Following the removal of Prevena, the wound and surrounding skin of the patient were observed. Wound healing was complete, and no skin lesion or tool-related complication was found around the wound due to NPWT. The Prevena NPWT system can be conveniently and safely implemented on the operational incision in renal transplant recipients in order to prevent surgical wound complications.
C1 [Bozkurt, B.; Tokac, M.; Dumlu, E. G.] Ataturk Training & Res Hosp, Organ Transplantat Ctr, Ankara, Turkey.
   [Yalcin, A.; Kilic, M.] Yildirim Beyazit Univ, Dept Gen Surg, Ankara, Turkey.
C3 Ankara Etlik Ihtisas Egitim ve Arastirma Hastanesi; Ankara Yildirim
   Beyazit University
RP Bozkurt, B (通讯作者)，Ataturk Training & Res Hosp, Organ Transplantat Ctr, Eskisehir Yolu 8 Km 2,Bilkent, Ankara, Turkey.
EM birkan.bozkurt@gmail.com
RI bozkurt, birkan/AAN-9219-2020; yalçın, abdussamed/JQW-2480-2023; TOKAÇ,
   MEHMET/AAA-9577-2021
OI TOKAÇ, MEHMET/0000-0002-7278-0937
CR Ashcroft GS, 1997, J INVEST DERMATOL, V108, P430, DOI 10.1111/1523-1747.ep12289705
   Ashcroft GS, 1998, LAB INVEST, V78, P47
   Atkins BZ, 2009, SURG INNOV, V16, P140, DOI 10.1177/1553350609334821
   Bozkurt B, 2013, TRANSPL P, V45, P901, DOI 10.1016/j.transproceed.2013.02.096
   Dean PG, 2004, TRANSPLANTATION, V77, P1555, DOI 10.1097/01.TP.0000123082.31092.53
   Fry D. E., SURG SITE INFECT PAT
   Gomoll AH, 2006, J ORTHOP TRAUMA, V20, P705, DOI 10.1097/01.bot.0000211159.98239.d2
   JUDSON RT, 1984, AUST NZ J SURG, V54, P223, DOI 10.1111/j.1445-2197.1984.tb05307.x
   Kilpadi DV, 2011, WOUND REPAIR REGEN, V19, P588, DOI 10.1111/j.1524-475X.2011.00714.x
   Mehrabi A, 2006, CLIN TRANSPLANT, V20, P97, DOI 10.1111/j.1399-0012.2006.00608.x
   Nashan B, 2012, TRANSPLANTATION, V94, P547, DOI 10.1097/TP.0b013e3182551021
   Shrestha A, 2010, ANN TRANSPL, V15, P5
   Stannard JP, 2006, J TRAUMA, V60, P1301, DOI 10.1097/01.ta.0000195996.73186.2e
   Stannard JR, 2009, OSTOMY WOUND MANAG, V55, P58
   Wilkes RP, 2012, SURG INNOV, V19, P67, DOI 10.1177/1553350611414920
   Witte MB, 1997, SURG CLIN N AM, V77, P509, DOI 10.1016/S0039-6109(05)70566-1
NR 16
TC 8
Z9 9
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0041-1345
EI 1873-2623
J9 TRANSPL P
JI Transplant. Proc.
PD JUN
PY 2015
VL 47
IS 5
BP 1515
EP 1517
DI 10.1016/j.transproceed.2015.04.057
PG 3
WC Immunology; Surgery; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Immunology; Surgery; Transplantation
GA CL6GY
UT WOS:000357066800067
PM 26093755
DA 2026-07-24
ER

PT J
AU Ahmed, M
   Nadeem, M
   Bin Shahzad, U
   Salim, H
AF Ahmed, Muhammad
   Nadeem, Manal
   Bin Shahzad, Umer
   Salim, Humzah
TI "Evaluating wound closure innovations in spinal surgery: impacts on
   efficiency and patient outcomes"
SO NEUROSURGICAL REVIEW
LA English
DT Letter
DE Wound closure; Spinal surgery; Barbed sutures; STRATAFIX Symmetric; Skin
   staples; Surgical site infections (SSIs); Plastic surgery closure
AB This study evaluates contemporary wound closure techniques in spinal surgery, focusing on the efficacy of barbed sutures, skin staples, and negative-pressure wound therapy (NPWT), compared to traditional methods. Barbed sutures, like STRATAFIX (TM) Symmetric, and skin staples demonstrate significant advantages, including reduced wound closure time, lower infection rates, and improved surgical outcomes, particularly in multilevel or revisional procedures. In contrast, plastic surgery closures do not show a substantial reduction in postoperative complications despite being used in more complex cases. NPWT is highlighted as an effective adjunct therapy for managing surgical site infections and reducing the need for hardware removal. The findings suggest that while modern techniques offer clear benefits, traditional methods remain valuable in specific contexts. The review advocates for further research through large-scale, long-term studies and emphasizes the need for personalized wound closure strategies based on individual patient risk factors.
C1 [Ahmed, Muhammad; Nadeem, Manal; Bin Shahzad, Umer; Salim, Humzah] Islamic Int Med Coll, Rawalpindi, Pakistan.
RP Ahmed, M (通讯作者)，Islamic Int Med Coll, Rawalpindi, Pakistan.
EM muhammadahmedsheikh20@gmail.com; drmanalnadeem@gmail.com;
   ushahzad912@gmail.com; humzahsalim0@gmail.com
RI Ahmed, Muhammad/JDV-9513-2023
OI BIN SHAHZAD, UMER/0009-0009-6538-5435
CR Akshay P, 2024, CUREUS J MED SCIENCE, V16, DOI 10.7759/cureus.63254
   Glener SR, 2024, NEUROSURG REV, V47, DOI 10.1007/s10143-024-02671-y
   Hersh AM, 2021, CLIN NEUROL NEUROSUR, V207, DOI 10.1016/j.clineuro.2021.106800
   Karaaslan F, 2015, INT MED CASE REP J, V8, P7, DOI 10.2147/IMCRJ.S76214
   Mun J, 2023, NEUROSPINE, V20, P981
NR 5
TC 1
Z9 1
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0344-5607
EI 1437-2320
J9 NEUROSURG REV
JI Neurosurg. Rev.
PD SEP 5
PY 2024
VL 47
IS 1
AR 546
DI 10.1007/s10143-024-02789-z
PG 2
WC Clinical Neurology; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Neurosciences & Neurology; Surgery
GA F1Y4O
UT WOS:001307842600001
PM 39235672
DA 2026-07-24
ER

PT J
AU Cholok, D
   Saberski, E
   Lowenberg, DW
AF Cholok, David
   Saberski, Ean
   Lowenberg, David W.
TI Approach to Complex Lower Extremity Reconstruction
SO SEMINARS IN PLASTIC SURGERY
LA English
DT Article
DE negative pressure wound therapy; fractures; lower extremity
ID FREE-TISSUE TRANSFER; OPEN TIBIAL FRACTURES; MICROSURGICAL
   RECONSTRUCTION; FLAP COVERAGE; MUSCLE FLAP; MANAGEMENT; OUTCOMES;
   TRAUMA; COMPLICATIONS; SALVAGE
AB Composite injuries to the lower extremity from etiologies including trauma and infection present a complex dilemma for the reconstructive surgeon, and require multidisciplinary collaboration amongst plastic, vascular, and orthopaedic surgical specialties. Here we present our algorithm for lower-extremity reconstructive management, refined over the last decades to provide an optimized outcome for our patients. Reconstruction is predicated on the establishment of a clean and living wound, where quality of the wound-bed is prioritized over timing to soft-tissue coverage. Once established, soft-tissues and fractures are provisionally stabilized; our preference for definitive coverage is for microvascular free-tissue, due to the paucity of healthy soft-tissue available at the injury, and ability to avoid the zone of injury for microvascular anastomosis. Finally, definitive bony reconstruction is dictated by the length and location of long-bone defect, with a preference to utilize bone transport for defects longer than 5 cm.
C1 [Cholok, David] Stanford Univ, Div Plast & Reconstruct Surg, Sch Med, 770 Welch Rd,Suite 400, Palo Alto, CA 94304 USA.
   [Saberski, Ean] Walter Reed Natl Mil Med Ctr, Dept Gen Surg, Bethesda, MD USA.
   [Lowenberg, David W.] Stanford Univ, Dept Orthoped Surg, Sch Med, Palo Alto, CA 94304 USA.
C3 Stanford University; Walter Reed National Military Medical Center;
   Stanford University
RP Cholok, D (通讯作者)，Stanford Univ, Div Plast & Reconstruct Surg, Sch Med, 770 Welch Rd,Suite 400, Palo Alto, CA 94304 USA.
EM dcholok@stanford.edu
OI Lowenberg, David/0000-0001-6416-1063
CR Abd-Al-Moktader MA, 2018, J RECONSTR MICROSURG, V34, P616, DOI 10.1055/s-0038-1661366
   [Anonymous], ROCKW GREENS FRACT A
   Bishop JA, 2012, J AM ACAD ORTHOP SUR, V20, P273, DOI 10.5435/JAAOS-20-05-273
   Bosse MJ, 2002, NEW ENGL J MED, V347, P1924, DOI 10.1056/NEJMoa012604
   Bosse MJ, 2001, J BONE JOINT SURG AM, V83A, P3, DOI 10.2106/00004623-200101000-00002
   Cho EH, 2018, PLAST RECONSTR SURG, V141, P191, DOI 10.1097/PRS.0000000000003927
   Cho EH, 2016, MICROSURG, V36, P276, DOI 10.1002/micr.22406
   Choudry U, 2008, PLAST RECONSTR SURG, V122, P479, DOI 10.1097/PRS.0b013e31817d60e0
   Court-Brown CM, 2012, INJURY, V43, P891, DOI 10.1016/j.injury.2011.12.007
   FEIBEL RJ, 1994, J TRAUMA, V37, P322, DOI 10.1097/00005373-199408000-00027
   Fischer JP, 2013, J RECONSTR MICROSURG, V29, P407, DOI 10.1055/s-0033-1343952
   FRANCEL TJ, 1992, PLAST RECONSTR SURG, V89, P478, DOI 10.1097/00006534-199203000-00014
   GEORGIADIS GM, 1993, J BONE JOINT SURG AM, V75A, P1431, DOI 10.2106/00004623-199310000-00003
   GODINA M, 1986, PLAST RECONSTR SURG, V78, P285, DOI 10.1097/00006534-198609000-00001
   GOSAIN A, 1990, PLAST RECONSTR SURG, V86, P1152, DOI 10.1097/00006534-199012000-00019
   GOTTLIEB LJ, 1994, PLAST RECONSTR SURG, V93, P1503, DOI 10.1097/00006534-199406000-00027
   GUSTILO RB, 1984, J TRAUMA, V24, P742, DOI 10.1097/00005373-198408000-00009
   GUSTILO RB, 1976, J BONE JOINT SURG AM, V58, P453, DOI 10.2106/00004623-197658040-00004
   Halawi MJ, 2015, ORTHOPEDICS, V38, pE1025, DOI 10.3928/01477447-20151020-12
   Harris AM, 2009, J ORTHOP TRAUMA, V23, P1, DOI 10.1097/BOT.0b013e31818e43dd
   HENRY SL, 1993, CLIN ORTHOP RELAT R, P54
   HESSEL SJ, 1981, RADIOLOGY, V138, P273, DOI 10.1148/radiology.138.2.7455105
   Higgins TF, 2010, ORTHOP CLIN N AM, V41, P233, DOI 10.1016/j.ocl.2009.12.006
   Hill JB, 2013, MICROSURG, V33, P9, DOI 10.1002/micr.21994
   Hu QF, 2020, INT WOUND J, V17, P708, DOI 10.1111/iwj.13330
   JOHANSEN KAJ, 1991, J TRAUMA, V31, P515, DOI 10.1097/00005373-199104000-00011
   Karanas YL, 2008, MICROSURG, V28, P632, DOI 10.1002/micr.20551
   Karger C, 2012, ORTHOP TRAUMATOL-SUR, V98, P97, DOI 10.1016/j.otsr.2011.11.001
   Lack WD, 2015, J ORTHOP TRAUMA, V29, P1, DOI [10.1097/bot.0000000000000262, 10.1097/BOT.0000000000000262, 10.1016/j.mporth.2014.12.008]
   Laughlin R T, 1993, J Orthop Trauma, V7, P123, DOI 10.1097/00005131-199304000-00004
   Lee ZH, 2019, PLAST RECONSTR SURG, V144, P759, DOI 10.1097/PRS.0000000000005955
   Liu DSH, 2012, INJURY, V43, P772, DOI 10.1016/j.injury.2011.09.003
   Lowenberg DW, 2013, J ORTHOP TRAUMA, V27, P576, DOI 10.1097/BOT.0b013e31828afde4
   Lowenberg DW, 2008, MICROSURG, V28, P623, DOI 10.1002/micr.20577
   Lowenberg DW, 1996, CLIN ORTHOP RELAT R, P37
   Lowenberg DW., 1996, TECH ORTHOP, V11, P210
   Lowenberg DW., 2014, COMPREHENSIVE ORTHOP, V275, P284
   MacKenzie Ellen J, 2006, J Am Acad Orthop Surg, V14, pS205
   Masquelet A C, 2000, Ann Chir Plast Esthet, V45, P346
   MATHES SJ, 1982, PLAST RECONSTR SURG, V69, P815, DOI 10.1097/00006534-198205000-00018
   Mckee MD, 2008, J ORTHOP TRAUMA, V22, P183, DOI 10.1097/BOT.0b013e3181678a64
   Miyamoto S, 2013, MICROSURG, V33, P60, DOI 10.1002/micr.22043
   Momoh AO, 2015, PLAST RECONSTR SURG, V136, P1337, DOI [10.1097/01.prs.0000472424.04551.8d, 10.1097/PRS.0000000000001814]
   Nance ML, 2012, National Trauma Data Bank 2012 Annual Report
   Patterson MJ, 1999, J ORTHOP TRAUMA, V13, P85, DOI 10.1097/00005131-199902000-00003
   PATZAKIS MJ, 1989, CLIN ORTHOP RELAT R, P36
   Rubin GD, 2001, RADIOLOGY, V221, P146, DOI 10.1148/radiol.2211001325
   Seamon MJ, 2009, J TRAUMA, V67, P238, DOI 10.1097/TA.0b013e3181a51bf9
   Shafiq B, 2021, J AM ACAD ORTHOP SUR, V29, pE536, DOI 10.5435/JAAOS-D-20-00502
   Sheckter CC, 2018, PLAST RECONSTR SURG, V142, P1337, DOI 10.1097/PRS.0000000000004885
   Sirkin M, 1999, J ORTHOP TRAUMA, V13, P78, DOI 10.1097/00005131-199902000-00002
   Steiert AE, 2009, J PLAST RECONSTR AES, V62, P675, DOI 10.1016/j.bjps.2007.09.041
   Swiontkowski MF, 2002, J TRAUMA, V52, P641, DOI 10.1097/00005373-200204000-00005
   WAUGH JR, 1992, RADIOLOGY, V182, P243, DOI 10.1148/radiology.182.1.1727290
   Xiong LY, 2016, MICROSURG, V36, P511, DOI 10.1002/micr.30020
NR 55
TC 8
Z9 8
U1 0
U2 0
PU THIEME MEDICAL PUBL INC
PI NEW YORK
PA 333 SEVENTH AVE, NEW YORK, NY 10001 USA
SN 1535-2188
EI 1536-0067
J9 SEMIN PLAST SURG
JI Semin. Plast. Surg.
PD NOV
PY 2022
VL 36
IS 04
BP 233
EP 242
DI 10.1055/s-0042-1758205
EA NOV 2022
PG 10
WC Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Surgery
GA 7D8XU
UT WOS:000886609700002
PM 36561427
OA Green Submitted
DA 2026-07-24
ER

PT J
AU Rauch-Pucher, M
   McCartney, T
   Cox-Reber, J
   Markwell, A
AF Rauch-Pucher, Mackenzie
   McCartney, Teresa
   Cox-Reber, Jessica
   Markwell, Ashley
TI Abdominal Soft Tissue Infection Caused by Mycobacterium wolinskyi
   After Cosmetic Surgery A Case Report
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
DE Mycobacterium wolinskyi; Negative pressure wound therapy; Wound care
   nurse
AB BACKGROUND: Mycobacterium wolinskyi is a rare, fast-growing, painful bacterium causing soft tissue infections. Sparse case reports focus on long-term intravenous antibiotic therapy and surgical interventions. We searched the literature and found almost no discussion about treatment from a nursing and wound care perspective. CASE: Ms P, a 30-year-old Arabic female patient, underwent cosmetic surgery in Iraq including liposuction, abdominoplasty, and herniorrhaphy. One month postoperatively, she presented with an infection identified as M. wolinskyi resulting in multiple hospital admissions. Ms P received treatment with long-term antibiotic therapy and underwent multiple surgical debridements with extensive wound care management. CONCLUSION: Mycobacterium wolinskyi is an exceedingly rare bacterium not typically seen in the clinical setting and requires prolonged and aggressive treatment. It is painful and fast-growing, as evidenced by multiple abscess formations and tissue necrosis in this case. Daily assessments and wound management using a collaborative approach were important to promote optimal healing.
C1 [Rauch-Pucher, Mackenzie; McCartney, Teresa; Cox-Reber, Jessica; Markwell, Ashley] Beaumont Hosp, 18101 Oakwood Blvd, Dearborn, MI 48124 USA.
C3 Beaumont Health
RP Markwell, A (通讯作者)，Beaumont Hosp, 18101 Oakwood Blvd, Dearborn, MI 48124 USA.
EM Ashley.stoeckle@beaumont.org
CR Bhatnagar Nishit, 2019, JBJS Case Connect, V9, pe0315, DOI [10.2106/jbjs.cc.18.00315, 10.2106/JBJS.CC.18.00315]
   Bossart S, 2016, CASE REP DERMATOL, V8, P151, DOI 10.1159/000446470
   Chouliara Z., 2020, Dermatol Nurs, V19, P36
   Dupont C, 2016, J HOSP INFECT, V93, P235, DOI 10.1016/j.jhin.2016.03.024
   Fujikura H, 2017, INTERNAL MED, V56, P3097, DOI 10.2169/internalmedicine.8871-17
   Kitajima H, 2021, J INFECT CHEMOTHER, V27, P766, DOI 10.1016/j.jiac.2020.12.019
   Krasner DL., 2016, Acute & Chronic Wounds: Current Management Concepts, P386
   Lalezari S, 2017, INT WOUND J, V14, P649, DOI 10.1111/iwj.12658
   Lima AS, 2013, INFECT DIS REP, V5, P40, DOI 10.4081/idr.2013.e12
   Panayi AC, 2017, World Journal of Dermatology, V6, P1, DOI [10.5314/wjd.v6.i1.1, 10.5314/wjd.v6.i1.1, DOI 10.5314/WJD.V6.I1.1]
   Saim S., 2016, Acute & Chronic Wounds: Current Management Concepts, P325
   Yoo SJ, 2013, BMC INFECT DIS, V13, DOI 10.1186/1471-2334-13-479
NR 12
TC 2
Z9 4
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD NOV-DEC
PY 2021
VL 48
IS 6
BP 573
EP 577
DI 10.1097/WON.0000000000000826
PG 5
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA WX4AB
UT WOS:000718539500015
PM 34781315
DA 2026-07-24
ER

PT J
AU Bird, JE
AF Bird, Justin E.
TI "Advances in the Surgical Management of Bone Tumors"
SO CURRENT ONCOLOGY REPORTS
LA English
DT Article
DE Bone tumor; Musculoskeletal surgery; Tumor resection; Navigation;
   Computer-assisted surgery; Negative pressure wound therapy; Orthopedic
   oncology; Technology; Megaprosthesis; Antibacterial coatings;
   Osteointegration; Orthopedic implants
ID COMPUTER NAVIGATION; OSTEOID OSTEOMA; ORTHOPEDIC-SURGERY;
   PROGNOSTIC-FACTORS; IMAGE GUIDANCE; RESECTION; CHONDROSARCOMA; PELVIS;
   RECONSTRUCTION; ACCURACY
AB Bone tumor surgery is extremely challenging, particularly when tumors are located in tightly confined anatomical areas and abutting critical organs and neurovascular structures. Tumor resection requires good cutting accuracy to ensure safety, to achieve negative margins, and to preserve critical structures when possible. The purpose of this paper was to review the literature on the surgical advances for bone tumor surgery published within the last year. The majority of literature identified focused on computer-assisted surgical approaches. There is increasing evidence that 3D navigation plays an important role in the resection of bone tumors. Reconstruction materials that encourage healing and prevent infections are also in development. Optimal care includes execution of a well-developed pre-operative plan using a multidisciplinary approach led by the orthopaedic oncologist.
C1 Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA.
C3 University of Texas System; UTMD Anderson Cancer Center
RP Bird, JE (通讯作者)，Univ Texas MD Anderson Canc Ctr, 1400 Pressler St Suite FCT 10-5054, Houston, TX 77030 USA.
EM jebird@mdanderson.org
OI Bird, Justin/0000-0002-7537-3018
CR Agrawal N, 2013, J RECONSTR MICROSURG, V29, P107, DOI 10.1055/s-0032-1329920
   Akiyama T, 2013, J ORTHOP RES, V31, P1195, DOI 10.1002/jor.22357
   Allam Y, 2013, EUR SPINE J, V22, P648, DOI 10.1007/s00586-012-2505-7
   Aponte-Tinao LA, 2014, ORTHOP CLIN N AM, V45, P257, DOI 10.1016/j.ocl.2013.12.008
   Aponte-Tinao LA, 2013, ORTHOPEDICS, V36, pE325, DOI 10.3928/01477447-20130222-21
   Biau D, 2006, J BONE JOINT SURG AM, V88A, P1285, DOI 10.2106/JBJS.E.00553
   Bruns J, 2007, J BONE JOINT SURG BR, V89B, P1084, DOI 10.1302/0301-620X.89B8
   Bullock P, 2013, INT J ORAL MAX SURG, V42, P970, DOI 10.1016/j.ijom.2013.04.019
   Campanacci DA, 2014, INJURY, V45, P399, DOI 10.1016/j.injury.2013.10.012
   Campos WK, 2013, CLIN ORTHOP RELAT R, V471, P680, DOI 10.1007/s11999-012-2725-5
   Cartiaux O, 2008, ACTA ORTHOP, V79, P695, DOI 10.1080/17453670810016731
   Cartiaux O, 2014, ANN BIOMED ENG, V42, P205, DOI 10.1007/s10439-013-0890-7
   Cartiaux O, 2013, COMPUT AIDED SURG, V18, P19, DOI 10.3109/10929088.2012.744096
   Cengic T, 2013, ACTA CLIN CROAT, V52, P261
   Coathup MJ, 2013, J BONE JOINT SURG AM, V95A, P1569, DOI 10.2106/JBJS.L.00362
   De Giglio E, 2013, ANAL BIOANAL CHEM, V405, P805, DOI 10.1007/s00216-012-6293-z
   Della Valle C, 2012, INT J ARTIF ORGANS, V35, P864, DOI 10.5301/ijao.5000161
   Delloye C, 2007, J BONE JOINT SURG AM, V89A, P579, DOI 10.2106/JBJS.F.00943
   Ding GX, 2013, RADIOTHER ONCOL, V108, P91, DOI 10.1016/j.radonc.2013.05.034
   EVANS HL, 1977, CANCER-AM CANCER SOC, V40, P818, DOI 10.1002/1097-0142(197708)40:2<818::AID-CNCR2820400234>3.0.CO;2-B
   Falagas ME, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0064741
   Fletcher C.D.M., 2013, WHO Classification of Tumours of Soft Tissue and Bone, V5
   Gao Q, 2013, COMPUT MED IMAG GRAP, V37, P183, DOI 10.1016/j.compmedimag.2013.01.001
   Gerbers JG, 2013, COMPUT AIDED SURG, V18, P27, DOI 10.3109/10929088.2012.743587
   Gulati K, 2012, ACTA BIOMATER, V8, P449, DOI 10.1016/j.actbio.2011.09.004
   Hacihaliloglu I, 2013, INT J COMPUT ASS RAD, V8, P157, DOI 10.1007/s11548-012-0747-9
   Harris JD, 2013, ORTHOPEDICS, V36, pE126, DOI 10.3928/01477447-20121217-32
   He PF, 2013, J BIOMED MATER RES A, V101, P555, DOI 10.1002/jbm.a.34333
   Italiano A, 2013, ANN ONCOL, V24, P2916, DOI 10.1093/annonc/mdt374
   Jennison T, 2014, ACTA BIOMATER, V10, P595, DOI 10.1016/j.actbio.2013.09.019
   Jeys L, 2013, BONE JOINT J, V95B, P1417, DOI 10.1302/0301-620X.95B10.31734
   Kang HG, 2014, MINIM INVASIV THER, V23, P58, DOI 10.3109/13645706.2013.835321
   Karlakki S, 2013, BONE JOINT RES, V2, P276, DOI 10.1302/2046-3758.212.2000190
   Khan F, 2013, CLIN ORTHOP RELAT R, V471, P851, DOI 10.1007/s11999-012-2529-7
   Kose N, 2013, CLIN ORTHOP RELAT R, V471, P2532, DOI 10.1007/s11999-013-2894-x
   Mezger U, 2013, LANGENBECK ARCH SURG, V398, P501, DOI 10.1007/s00423-013-1059-4
   Miyazaki Tsuyoshi, 2013, J Med Case Rep, V7, P164, DOI 10.1186/1752-1947-7-164
   Moore AT, 2006, CLIN ORTHOP RELAT R, P22, DOI 10.1097/01.blo.0000246558.27596.7a
   Müller PE, 2002, INT ORTHOP, V26, P76, DOI 10.1007/s00264-001-0322-4
   Natarajan MV, 2007, ACTA ORTHOP BELG, V73, P462
   O'Donnell PW, 2014, CLIN ORTHOP RELAT R, V472, P849, DOI 10.1007/s11999-013-3022-7
   Pring ME, 2001, J BONE JOINT SURG AM, V83A, P1630, DOI 10.2106/00004623-200111000-00003
   Ritacco LE, 2013, STUD HEALTH TECHNOL, V192, P1162, DOI 10.3233/978-1-61499-289-9-1162
   Ritacco LE, 2013, ORTHOPEDICS, V36, pE942, DOI 10.3928/01477447-20130624-27
   Rudert M, 2012, OPER ORTHOP TRAUMATO, V24, P196, DOI 10.1007/s00064-012-0161-z
   Satcher RL, 2013, ORTHOP CLIN N AM, V44, P645, DOI 10.1016/j.ocl.2013.07.001
   Schils F, 2013, EUR SPINE J, V22, P1758, DOI 10.1007/s00586-013-2702-z
   Sheth DS, 1996, CANCER, V78, P745, DOI 10.1002/(SICI)1097-0142(19960815)78:4<745::AID-CNCR9>3.0.CO;2-D
   So TYC, 2010, CLIN ORTHOP RELAT R, V468, P2985, DOI 10.1007/s11999-010-1465-7
   Stübig T, 2013, INT J MED ROBOT COMP, V9, P480, DOI 10.1002/rcs.1519
   Sugano N, 2013, CLIN ORTHOP SURG, V5, P1, DOI 10.4055/cios.2013.5.1.1
   Weber KL, 2002, CLIN ORTHOP RELAT R, P19
   Wong KC, 2013, CLIN ORTHOP RELAT R, V471, P750, DOI 10.1007/s11999-012-2557-3
   Wong KC, 2013, CLIN ORTHOP RELAT R, V471, P762, DOI 10.1007/s11999-012-2536-8
   Wong KC, 2014, CURR SURG REP, V2, DOI 10.1007/s40137-014-0047-0
NR 55
TC 8
Z9 9
U1 0
U2 20
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1523-3790
EI 1534-6269
J9 CURR ONCOL REP
JI Curr. Oncol. Rep.
PD JUL
PY 2014
VL 16
IS 7
AR 392
DI 10.1007/s11912-014-0392-2
PG 6
WC Oncology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology
GA AJ5RG
UT WOS:000337743000002
PM 24853049
DA 2026-07-24
ER

PT J
AU Arhi, C
   El-Gaddal, A
AF Arhi, Chanpreet
   El-Gaddal, Ahmed
TI Use of a Silver Dressing for Management of an Open Abdominal Wound
   Complicated by an Enterocutaneous Fistula-From Hospital to Community
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
ID OPEN ABDOMEN
AB BACKGROUND: Management of an open abdominal wound complicated by an enterocutaneous fistula poses multiple challenges. The enterocutaneous fistula we discuss opened directly into the abdominal wound, without forming a track through skin.
   CASE: We discuss a patient who underwent a Hartmann's procedure for diverticulitis, followed by repeat laparotomies for washout. Due to the edematous bowel and ongoing sepsis, it was not possible to close the abdomen by primary closure. Negative pressure wound therapy (NPWT) has been used successfully in these circumstances. However, the position of an enterocutaneous fistula prevented application of NPWT, and a more conservative approach was used to reduce infection and enable wound closure by secondary intention.
   CONCLUSION: Owing to the presence of an enterocutaneous fistula, we applied a silver-based dressing as an alternative to NPWT. The silver-based dressing was initially applied during the patient's hospital course and continued into the community, ultimately resulting in closure of the wound and fistula.
C1 [Arhi, Chanpreet; El-Gaddal, Ahmed] Queen Elizabeth Hosp, London SE18 4QH, England.
RP El-Gaddal, A (通讯作者)，Queen Elizabeth Hosp, Stadium Rd, London SE18 4QH, England.
EM ahmed.elgaddal@nhs.net
CR Coutts Pat, 2005, Int Wound J, V2, P348
   D'Hondt M, 2011, AM J SURG, V202, pE20, DOI 10.1016/j.amjsurg.2010.06.025
   Dowsett Caroline, 2003, Br J Nurs, V12, pS44
   Fong J, 2006, INT J NANOMED, V1, P441, DOI 10.2147/nano.2006.1.4.441
   Gabriel A, 2006, WOUNDS, V18, P245
   Girard S, 2002, AM J SURG, V184, P166, DOI 10.1016/S0002-9610(02)00916-9
   Goverman J, 2006, J TRAUMA, V60, P428, DOI 10.1097/01.ta.0000203588.66012.c4
   Guo S, 2010, J DENT RES, V89, P219, DOI 10.1177/0022034509359125
   Jamshidi R, 2007, ARCH SURG-CHICAGO, V142, P793, DOI 10.1001/archsurg.142.8.793
   Moiemen NS, 2011, BURNS, V37, P27, DOI 10.1016/j.burns.2010.09.006
   Thomas S, 2003, J Wound Care, V12, P101
   Totaro Pasquale, 2009, Interact Cardiovasc Thorac Surg, V8, P153, DOI 10.1510/icvts.2008.188870
   Trevelyan S L, 2009, J Wound Care, V18, P24
   Velnar T, 2009, J INT MED RES, V37, P1528, DOI 10.1177/147323000903700531
NR 14
TC 5
Z9 5
U1 0
U2 9
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JAN-FEB
PY 2013
VL 40
IS 1
BP 101
EP 103
DI 10.1097/WON.0b013e318279bfa5
PG 3
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 063UP
UT WOS:000313027800014
PM 23277219
DA 2026-07-24
ER

PT J
AU Franklin, C
AF Franklin, Christoph
TI The Suction Pouch for Management of Simple or Complex Enterocutaneous
   Fistulae
SO JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
LA English
DT Article
AB Containing effluent from an enterocutaneous fistula (ECF) requires expertise, critical thinking skills, and creativity. Using a combination of products readily available to WOC nurses practicing in the United States, I have designed a suction pouch that reliably contains fistula output. A standard ostomy pouch can be converted into a suction pouch by adding a large, single-lumen catheter into the pouch, sealing it, and connecting the assembly to low continuous suction. The resulting pouch can be used by itself to drain effluent from an ECF or it can be used in combination with wound dressings, or a negative pressure wound therapy system. Application of a suction pouch extends the integrity of the appliance and diverts succus away from the wound bed or the newly applied skin graft with increased reliability. This article describes the technique used to create a suction pouch, followed by 4 brief case descriptions that demonstrate feasibility of its use for the management of ECFs.
C1 Vibra Specialty Hosp, Portland, OR 97220 USA.
RP Franklin, C (通讯作者)，Vibra Specialty Hosp, 10300 NE Hancock St, Portland, OR 97220 USA.
EM cfranklin@vshportland.com
CR Al-Khoury G, 2008, J AM COLL SURGEONS, V206, P397, DOI 10.1016/j.jamcollsurg.2007.07.027
   BRYANT R, 2007, ACUTE CHRONIC WOUNDS, P490
   Fischer JE, 2008, AM J SURG, V196, P1, DOI 10.1016/j.amjsurg.2008.01.001
   Goverman J, 2006, J TRAUMA, V60, P428, DOI 10.1097/01.ta.0000203588.66012.c4
   Jones Elizabeth Geiger, 2003, J Wound Ostomy Continence Nurs, V30, P351, DOI 10.1016/S1071-5754(03)00438-8
   Kordasiewicz Lynn M, 2004, J Wound Ostomy Continence Nurs, V31, P150
   Nienhuijs S W, 2003, J Wound Care, V12, P343
   Reed T, 2006, OSTOMY WOUND MANAG, V52, P60
   Wainstein Daniel Edgardo, 2008, World J Surg, V32, P430
NR 9
TC 9
Z9 11
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1071-5754
EI 1528-3976
J9 J WOUND OSTOMY CONT
JI J. Wound Ostomy Cont. Nurs.
PD JUL-AUG
PY 2010
VL 37
IS 4
BP 387
EP 392
DI 10.1097/WON.0b013e3181e3adb7
PG 6
WC Nursing
WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
SC Nursing
GA 628HK
UT WOS:000280106000008
PM 20571470
DA 2026-07-24
ER

PT J
AU Zia, A
   Hasan, M
   Ilyas, S
   Siddiqui, HU
   Tappuni, B
   Marsia, S
   Zubair, MM
   Raza, S
   Mustafa, RR
   Baloch, ZQ
   Deo, SV
   Sharma, UM
   Sheikh, MA
AF Zia, Aisha
   Hasan, Marium
   Ilyas, Sidra
   Siddiqui, Hafiz Umair
   Tappuni, Bassman
   Marsia, Shayan
   Zubair, M. Mujeeb
   Raza, Sajjad
   Mustafa, Rami R.
   Baloch, Zulfiqar Qutrio
   Deo, Salil V.
   Sharma, Umesh M.
   Sheikh, Mohammad Adil
TI Reining in Sternal Wound Infections: The Achilles' Heel of Bilateral
   Internal Thoracic Artery Grafting
SO SURGICAL INFECTIONS
LA English
DT Article
DE bilateral ITA grafting; CABG; sternal wound infections
ID LONG-TERM SURVIVAL; SURGICAL-SITE INFECTIONS; VACUUM-ASSISTED CLOSURE;
   STAPHYLOCOCCUS-AUREUS BACTEREMIA; GENTAMICIN-COLLAGEN SPONGE;
   MAMMARY-ARTERY; RISK-FACTORS; CARDIAC-SURGERY; METHICILLIN-RESISTANT;
   POSTOPERATIVE COMPLICATIONS
AB Background: Although the survival advantage of bilateral internal thoracic artery grafting (BITA) is well known in patients undergoing coronary artery bypass grafting (CABG), this technique has not been widely adopted. This is mainly because of the increased risk of deep sternal wound infections (DSWI) associated with its use. However, in recent years the overall risk of DSWI has decreased. This is mainly because of strategies that have been adopted to decrease the risk of these infections in patients undergoing CABG.
   Conclusion: In this review we identified DSWI preventive strategies and described them in detail so that their use by surgeons can be increased. This would minimize the risk of DSWI after BITA grafting and maximize the use of this highly effective surgical technique.
C1 [Zia, Aisha; Siddiqui, Hafiz Umair; Tappuni, Bassman] Cleveland Clin, Heart & Vasc Inst, Dept Thorac & Cardiovasc Surg, Cleveland, OH 44106 USA.
   [Hasan, Marium] Kidney Ctr, Dept Urol, Karachi, Pakistan.
   [Ilyas, Sidra; Sheikh, Mohammad Adil] Wayne State Univ, Dept Med, Detroit Med Ctr, Detroit, MI 48202 USA.
   [Marsia, Shayan] Dow Univ Hlth Sci, Dow Med Coll, Karachi, Pakistan.
   [Zubair, M. Mujeeb] Houston Methodist Hosp, Methodist DeBakey Heart & Vasc Ctr, Houston, TX 77030 USA.
   [Raza, Sajjad; Mustafa, Rami R.; Deo, Salil V.] Univ Hosp Cleveland, Med Ctr, Cleveland, OH 44106 USA.
   [Baloch, Zulfiqar Qutrio] Brandon Reg Hosp, Dept Med, Brandon, FL USA.
   [Sharma, Umesh M.] Mayo Clin Hlth Syst, Community Div Hosp Med, Rochester, MN USA.
C3 Cleveland Clinic Foundation; Detroit Medical Center; Wayne State
   University; Dow University of Health Sciences; Dow Medical College;
   Houston Methodist; University System of Ohio; Case Western Reserve
   University; Case Western Reserve University Hospital; University
   Hospitals of Cleveland
RP Zubair, MM (通讯作者)，Houston Methodist Hosp, Methodist DeBakey Heart & Vasc Ctr, Houston, TX 77030 USA.
EM drmujeebzubair@gmail.com
RI DEO, SALIL/AHE-2796-2022; Mustafa, Rami/AEA-9712-2022; Marsia,
   Shayan/PMR-5451-2026
OI DEO, SALIL/0000-0002-4729-1461; Mustafa, Rami/0000-0001-5574-1269;
   Rizvi, Marium Hasan/0009-0001-8428-309X; 
CR Alasmari FA, 2012, MAYO CLIN PROC, V87, P1054, DOI 10.1016/j.mayocp.2012.05.026
   Anderson DJ, 2014, INFECT CONT HOSP EP, V35, P605, DOI 10.1086/676022
   [Anonymous], 2014, ISRN OBES
   [Anonymous], CURRENT CHALLENGES T
   ASPEN Board of Directors and the Clinical Guidelines Task Force, 2002, JPEN J Parenter Enteral Nutr, V26, p1SA
   Baillot R, 2010, EUR J CARDIO-THORAC, V37, P880, DOI 10.1016/j.ejcts.2009.09.023
   Bapat V, 2008, J CARDIAC SURG, V23, P227, DOI 10.1111/j.1540-8191.2008.00595.x
   Sá MPBD, 2013, INTERACT CARDIOV TH, V16, P849, DOI 10.1093/icvts/ivt012
   Bennett-Guerrero E, 2010, JAMA-J AM MED ASSOC, V304, P755, DOI 10.1001/jama.2010.1152
   Borger MA, 1998, ANN THORAC SURG, V65, P1050, DOI 10.1016/S0003-4975(98)00063-0
   Bratzler DW, 2005, ARCH SURG-CHICAGO, V140, P174, DOI 10.1001/archsurg.140.2.174
   Breithaupt Theresa, 2010, Proc (Bayl Univ Med Cent), V23, P79
   Brunet F, 1996, J THORAC CARDIOV SUR, V111, P1200
   Buxton BF, 1998, CIRCULATION, V98, pII1
   Caffarelli AD, 2006, J THORAC CARDIOV SUR, V131, P1338, DOI 10.1016/j.jtcvs.2005.11.047
   Calafiore AM, 2005, ANN THORAC SURG, V80, P888, DOI 10.1016/j.athoracsur.2005.03.077
   Cayci C, 2008, ANN PLAS SURG, V61, P294, DOI 10.1097/SAP.0b013e31815acb6a
   Crabtree Traves D, 2004, Semin Thorac Cardiovasc Surg, V16, P53
   De Geest S, 1996, Prog Cardiovasc Nurs, V11, P4
   Deo SV, 2013, ANN THORAC SURG, V95, P862, DOI 10.1016/j.athoracsur.2012.11.068
   DOEBBELING BN, 1993, CLIN INFECT DIS, V17, P466, DOI 10.1093/clinids/17.3.466
   Dryden MS, 2004, J HOSP INFECT, V56, P283, DOI 10.1016/j.jhin.2004.01.008
   Edwards FH, 2006, ANN THORAC SURG, V81, P397, DOI 10.1016/j.athoracsur.2005.06.034
   ElBardissi AW, 2012, J THORAC CARDIOV SUR, V143, P273, DOI 10.1016/j.jtcvs.2011.10.029
   Endo M, 2003, CIRCULATION, V108, P1343, DOI 10.1161/01.CIR.0000085995.87982.6E
   Endo M, 2001, CIRCULATION, V104, P2164, DOI 10.1161/hc4301.098283
   Engelman R, 2007, ANN THORAC SURG, V83, P1569, DOI 10.1016/j.athoracsur.2006.09.046
   Fouquet O, 2015, INTERACT CARDIOV TH, V20, P663, DOI 10.1093/icvts/ivv026
   Friberg Ö, 2006, THORAC CARDIOV SURG, V54, P468, DOI 10.1055/s-2006-924437
   Furnary AP, 1999, ANN THORAC SURG, V67, P352, DOI 10.1016/S0003-4975(99)00014-4
   Galbut DL, 2012, J THORAC CARDIOV SUR, V143, P844, DOI 10.1016/j.jtcvs.2011.12.026
   GALBUT DL, 1985, ANN THORAC SURG, V40, P264, DOI 10.1016/S0003-4975(10)60039-2
   Gibbs J, 1999, ARCH SURG-CHICAGO, V134, P36, DOI 10.1001/archsurg.134.1.36
   Gorlitzer M, 2013, INTERACT CARDIOV TH, V17, P515, DOI 10.1093/icvts/ivt240
   Gorlitzer M, 2010, INTERACT CARDIOV TH, V10, P714, DOI 10.1510/icvts.2009.223305
   Harbarth S, 1999, ANTIMICROB AGENTS CH, V43, P1412, DOI 10.1128/AAC.43.6.1412
   HENNESSEY PJ, 1991, JPEN-PARENTER ENTER, V15, P60, DOI 10.1177/014860719101500160
   Huang SS, 2007, J INFECT DIS, V195, P330, DOI 10.1086/510622
   Johnston DR, 2014, CURR OPIN CARDIOL, V29, P542, DOI 10.1097/HCO.0000000000000116
   Jones R, 2011, INTERACT CARDIOV TH, V12, P449, DOI 10.1510/icvts.2010.239863
   Kajimoto K, 2015, ANN THORAC SURG, V99, P1097, DOI 10.1016/j.athoracsur.2014.09.045
   Kamiya H, 2012, INTERACT CARDIOV TH, V15, P665, DOI 10.1093/icvts/ivs293
   Karas PL, 2015, INTERACT CARDIOV TH, V21, P777, DOI 10.1093/icvts/ivv247
   Kieser TM, 2014, J THORAC CARDIOV SUR, V148, P1887, DOI 10.1016/j.jtcvs.2014.02.022
   Kinoshita T, 2010, ANN THORAC SURG, V90, P1173, DOI 10.1016/j.athoracsur.2010.05.048
   KO W, 1992, ANN THORAC SURG, V53, P301, DOI 10.1016/0003-4975(92)91337-9
   Kowalewski M, 2015, J THORAC CARDIOV SUR, V149, P1631, DOI 10.1016/j.jtcvs.2015.01.034
   Kramer R, 2008, ARCH SURG-CHICAGO, V143, P451, DOI 10.1001/archsurg.143.5.451
   Kühme T, 2007, APMIS, V115, P1001, DOI 10.1111/j.1600-0463.2007.00832.x
   Kurlansky P, 2014, J THORAC CARDIOV SUR, V148, P1896, DOI 10.1016/j.jtcvs.2014.09.097
   Lazar HL, 2016, J THORAC CARDIOV SUR, V152, P962, DOI 10.1016/j.jtcvs.2016.01.060
   Lev-Ran O, 2003, ANN THORAC SURG, V75, P1872, DOI 10.1016/S0003-4975(03)00031-6
   LOOP FD, 1986, NEW ENGL J MED, V314, P1, DOI 10.1056/NEJM198601023140101
   Lytle BW, 2013, ANN CARDIOTHORAC SUR, V2, P485, DOI 10.3978/j.issn.2225-319X.2013.07.04
   Lytle BW, 2004, ANN THORAC SURG, V78, P2005, DOI 10.1016/j.athoracsur.2004.05.070
   Lytle BW, 1999, J THORAC CARDIOV SUR, V117, P855, DOI 10.1016/S0022-5223(99)70365-X
   Mangram AJ, 1999, INFECT CONT HOSP EP, V20, P250, DOI 10.1086/501620
   Matsa M, 2001, J THORAC CARDIOV SUR, V121, P668, DOI 10.1067/mtc.2001.112824
   Mavros MN, 2012, J THORAC CARDIOV SUR, V144, P1235, DOI 10.1016/j.jtcvs.2012.06.040
   McNair PD, 2009, HEALTH AFFAIR, V28, P1485, DOI 10.1377/hlthaff.28.5.1485
   NAGACHINTA T, 1987, J INFECT DIS, V156, P967, DOI 10.1093/infdis/156.6.967
   Nooh N, 2014, INDIAN J ORTHOP, V48, P319, DOI 10.4103/0019-5413.129451
   Olsen MA, 2002, J THORAC CARDIOV SUR, V124, P136, DOI 10.1067/mtc.2002.122306
   Peterson MD, 2003, J THORAC CARDIOV SUR, V126, P1314, DOI 10.1016/S0022-5223(03)00808-0
   Pevni D, 2003, ANN SURG, V237, P277, DOI 10.1097/00000658-200302000-00018
   Pick AW, 1997, ANN THORAC SURG, V64, P599, DOI 10.1016/S0003-4975(97)00620-6
   Pujol M, 1996, AM J MED, V100, P509, DOI 10.1016/S0002-9343(96)00014-9
   Puskas JD, 2012, ANN THORAC SURG, V94, P710, DOI 10.1016/j.athoracsur.2012.03.082
   Raza S, 2014, J THORAC CARDIOV SUR, V148, P1257, DOI 10.1016/j.jtcvs.2014.06.058
   Sakic A, 2013, INTERACT CARDIOV TH, V17, P378, DOI 10.1093/icvts/ivt089
   Schmidt SE, 1997, ANN THORAC SURG, V64, P9, DOI 10.1016/S0003-4975(97)00473-6
   Sepehripour AH, 2012, INTERACT CARDIOV TH, V15, P726, DOI 10.1093/icvts/ivs177
   SEYFER AE, 1988, SURGERY, V104, P899
   Singh Kimberly, 2011, Semin Plast Surg, V25, P25, DOI 10.1055/s-0031-1275168
   Sjögren J, 2006, EUR J CARDIO-THORAC, V30, P898, DOI 10.1016/j.ejcts.2006.09.020
   Song DH, 2004, EUR J CARDIO-THORAC, V26, P367, DOI 10.1016/j.ejcts.2004.04.038
   Spelman DW, 2000, AUST NZ J SURG, V70, P47, DOI 10.1046/j.1440-1622.2000.01742.x
   Tang Gilbert H L, 2004, Semin Thorac Cardiovasc Surg, V16, P62
   Tewarie LS, 2012, J CARDIOTHORAC SURG, V7, DOI 10.1186/1749-8090-7-85
   Trussell J, 2008, AM J SURG, V196, P883, DOI 10.1016/j.amjsurg.2008.07.024
   Tsang W, 2016, INTERACT CARDIOV TH, V23, P957, DOI 10.1093/icvts/ivw270
   ULICNY KS, 1991, J CARDIAC SURG, V6, P338, DOI 10.1111/j.1540-8191.1991.tb00322.x
   Vestergaard RF, 2010, J CARDIOTHORAC SURG, V5, DOI 10.1186/1749-8090-5-117
   Wang MY, 2001, NEUROSURGERY, V49, P962
   Wertheim HFL, 2004, LANCET, V364, P703, DOI 10.1016/S0140-6736(04)16897-9
   Yi GJ, 2014, CIRCULATION, V130, P539, DOI 10.1161/CIRCULATIONAHA.113.004255
   Zanetti G, 2001, EMERG INFECT DIS, V7, P828
   Zerr KJ, 1997, ANN THORAC SURG, V63, P356
NR 88
TC 7
Z9 8
U1 0
U2 0
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD MAY 1
PY 2020
VL 21
IS 4
BP 323
EP 331
DI 10.1089/sur.2018.142
PG 9
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Infectious Diseases; Surgery
GA LJ2YR
UT WOS:000530035700003
PM 31829828
OA Bronze
DA 2026-07-24
ER

PT J
AU Yamasaki, O
   Nagao, Y
   Sugiyama, N
   Otsuka, M
   Iwatsuki, K
AF Yamasaki, Osamu
   Nagao, Yoh
   Sugiyama, Narushi
   Otsuka, Masaki
   Iwatsuki, Keiji
TI Surgical management of axillary necrotizing fasciitis: A case report
SO JOURNAL OF DERMATOLOGY
LA English
DT Article
DE axilla; debridement; latissimus dorsi flap; Streptococcus pyogenes;
   toxic shock-like syndrome
ID CHEST-WALL
AB Axillary necrotizing fasciitis (NF) is quite rare and requires special management with respect to debridement and delayed surgical reconstruction. A 76-year-old man presented to our emergency department with a 2-day history of high fever, severe left axillary pain and redness. A few hours later, he developed discoloration and hemorrhagic bulla in the axilla, and the redness enlarged on the trunk. Emergency surgical debridement was performed. The blackish necrosis in the axilla was completely excised and the erythematous areas in the chest wall were cut down to the level of the fascia. Split-thickness skin grafts were applied during the second debridement on the 30th day of hospitalization and negative pressure wound therapy was used. Although the grafts took partially, full thickness axillary defects remained. We performed reconstruction with a pedicled latissimus dorsi flap on day 78. This case highlights some of the important surgical considerations in the management of axillary NF.
C1 [Yamasaki, Osamu] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Dermatol, Kita Ku, Okayama 7008558, Japan.
   [Sugiyama, Narushi] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Plast & Reconstruct Surg, Okayama Red Cross Hosp, Okayama 7008558, Japan.
C3 Okayama University; Okayama University
RP Yamasaki, O (通讯作者)，Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Dermatol, Kita Ku, 2-5-1 Shikata Cho, Okayama 7008558, Japan.
EM yamasa-o@cc.okayama-u.ac.jp
RI Yamasaki, Osamu/LZE-5515-2025
FU Grants-in-Aid for Scientific Research [23591646] Funding Source: KAKEN
CR Anaya DA, 2005, ARCH SURG-CHICAGO, V140, P151, DOI 10.1001/archsurg.140.2.151
   Basoglu M, 2007, SURG TODAY, V37, P558, DOI 10.1007/s00595-006-3391-6
   Brandstrom H, 1996, Lakartidningen, V93, P3687
   Cunningham JD, 2001, MT SINAI J MED, V68, P253
   Netscher DT, 2009, PLAST RECONSTR SURG, V124, p427E, DOI 10.1097/PRS.0b013e3181bf8323
   Sarani B, 2009, J AM COLL SURGEONS, V208, P279, DOI 10.1016/j.jamcollsurg.2008.10.032
   Skitarelic N, 2003, INFECTION, V31, P39, DOI 10.1007/s15010-002-3057-2
   Urschel JD, 1997, ANN THORAC SURG, V64, P276, DOI 10.1016/S0003-4975(97)00514-6
   Wong CH, 2003, J BONE JOINT SURG AM, V85A, P1454, DOI 10.2106/00004623-200308000-00005
   Wong Chin-Ho, 2008, Am J Surg, V196, pe19, DOI 10.1016/j.amjsurg.2007.08.076
NR 10
TC 5
Z9 9
U1 0
U2 1
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 0385-2407
J9 J DERMATOL
JI J. Dermatol.
PD MAR
PY 2012
VL 39
IS 3
BP 309
EP 311
DI 10.1111/j.1346-8138.2011.01456.x
PG 3
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA 897US
UT WOS:000300684500023
PM 22211460
DA 2026-07-24
ER

PT J
AU Baglioni, E
   Trovato, L
   Marcarelli, M
   Frenello, A
   Bocchiotti, MA
AF Baglioni, Elisabetta
   Trovato, Letizia
   Marcarelli, Marco
   Frenello, Ambra
   Bocchiotti, Maria Alessandra
TI Treatment of Oncological Post-surgical Wound Dehiscence with Autologous
   Skin Micrografts
SO ANTICANCER RESEARCH
LA English
DT Article
DE Dehiscence; Rigenera protocol; autologous micrografts
ID SURGERY; INFECTIONS; MANAGEMENT; DISEASE
AB Background/Aim. The closure of postoperative wounds is essential in order to prevent surgical site infections or wound dehiscence, mainly in oncological patients. We aimed to demonstrate the efficacy of autologous micrografts in the management of wound dehiscence in an oncology patient undergoing decompressive spinal laminectomy. Case Report: A 57-year-old man with IgG multiple myeloma and medullary plasmocytoma C7-T3, was to undergo decompressive spinal laminectomy and vertebral fixation leading to a wound dehiscence with exposed instrumentation. Autologous micrografts were obtained by Rigenera protocol and directly applied to the dehisced wound. After 60 days of negative pressure wound therapy, we observed reduction of the diameter and depth of wound dehiscence, with a coverage of instrumentation, without complete re-epithelialization, that instead was reached by application of autologous micrografts after 70 days. Conclusion: The Rigenera protocol may be the solution for complex wounds in oncological and immune-compromised patients where other treatments are contraindicated.
C1 [Baglioni, Elisabetta; Frenello, Ambra; Bocchiotti, Maria Alessandra] Univ Turin, San Giovanni Battista Hosp, Dept Plast & Reconstruct Surg, Coros Dogliotti 14, I-10126 Turin, Italy.
   [Trovato, Letizia] Univ Turin, Dept Med Sci, Coros Dogliotti 14, I-10126 Turin, Italy.
   [Marcarelli, Marco] Santa Croce Hosp, Unit Orthoped & Traumatoly, Moncalieri, Italy.
C3 A.O.U. Citta della Salute e della Scienza di Torino; AOU San Giovanni
   Battista-Molinette; University of Turin; University of Turin
RP Trovato, L (通讯作者)，Univ Turin, Dept Med Sci, Coros Dogliotti 14, I-10126 Turin, Italy.
EM letizia.trovato@unito.it
RI marcarelli, marco/AFT-6850-2022
OI marcarelli, marco/0000-0003-3184-417X; Bocchiotti, Maria
   Alessana/0000-0003-0723-1074; Trovato, Letizia/0000-0001-6004-795X
CR [Anonymous], COCHRANE DATABASE SY
   Banwell P E, 1999, J Wound Care, V8, P79
   Banwell Paul E, 2004, Int Wound J, V1, P95, DOI 10.1111/j.1742-4801.2004.00031.x
   Bir SC, 2009, J VASC SURG, V50, P870, DOI 10.1016/j.jvs.2009.06.016
   Boone JD, 2013, GYNECOL ONCOL, V131, P123, DOI 10.1016/j.ygyno.2013.06.041
   Brunelli Giorgio, 2013, J Indian Soc Periodontol, V17, P644, DOI 10.4103/0972-124X.119284
   Cong ZJ, 2014, INT SURG, V99, P112, DOI 10.9738/INTSURG-D-13-00059
   Dea N, 2014, J NEUROSURG-SPINE, V21, P698, DOI 10.3171/2014.7.SPINE131007
   Dormand Emma-Louise, 2005, Int Wound J, V2, P112, DOI 10.1111/j.1742-4801.2005.00079.x
   Furlan JC, 2012, NEURO-ONCOLOGY, V14, P631, DOI 10.1093/neuonc/nos062
   Galliera E, 2012, J Biol Regul Homeost Agents, V26, p35S
   Gaston RG, 2012, CRIT CARE NURS CLIN, V24, P323, DOI 10.1016/j.ccell.2012.03.007
   Giaccone M., 2014, J Stem Cells Res Rev & Rep., V1, P3
   Graziano A, 2013, ANN ORAL MAXILLOFACI, V2, P20
   Haubner F, 2012, RADIAT ONCOL, V7, DOI 10.1186/1748-717X-7-162
   Lia XH, 2008, CORONARY ARTERY DIS, V19, P363, DOI 10.1097/MCA.0b013e3282fc6165
   McNees Patrick, 2006, Semin Oncol Nurs, V22, P130, DOI 10.1016/j.soncn.2006.04.003
   McNees P, 2007, OSTOMY WOUND MANAG, V53, P70
   Meaunne S, 2013, J TISSUE VIABILITY, V22, P122, DOI 10.1016/j.jtv.2013.07.001
   Morris CD, 2003, ANN SURG ONCOL, V10, P778, DOI 10.1245/ASO.2003.07.023
   Ndayishimiye JMJ, 2009, ORTHOP TRAUMATOL-SUR, V95, pS35, DOI 10.1016/j.otsr.2009.03.007
   Novetsky AP, 2014, GYNECOL ONCOL, V134, P233, DOI 10.1016/j.ygyno.2014.06.012
   Ousey KJ, 2013, SPINE J, V13, P1393, DOI 10.1016/j.spinee.2013.06.040
   Purpura V, 2016, JOVE IN PRESS
   Schweinberger MH, 2008, CLIN PODIATR MED SUR, V26, P1
   Svolacchia F, 2016, J COSMET DERMATOL-US, V15, P245, DOI 10.1111/jocd.12212
   Trovato L, 2015, J CELL PHYSIOL, V230, P2299, DOI 10.1002/jcp.24973
   Viale Pamela Hallquist, 2006, Semin Oncol Nurs, V22, P144, DOI 10.1016/j.soncn.2006.04.007
   Vitaz TW, 2004, J NEUROSURG, V100, P46, DOI 10.3171/spi.2004.100.1.0046
   Yao KH, 2013, AUST FAM PHYSICIAN, V42, P867
   Zanzottera F., 2014, J Cosmet Dermatological Sci Appl, V4, P268, DOI [DOI 10.4236/JCDSA.2014.44036, 10.4236/JCDSA.2014.44036]
NR 31
TC 20
Z9 20
U1 0
U2 2
PU INT INST ANTICANCER RESEARCH
PI ATHENS
PA EDITORIAL OFFICE 1ST KM KAPANDRITIOU-KALAMOU RD KAPANDRITI, PO BOX 22,
   ATHENS 19014, GREECE
SN 0250-7005
EI 1791-7530
J9 ANTICANCER RES
JI Anticancer Res.
PD MAR
PY 2016
VL 36
IS 3
BP 975
EP 979
PG 5
WC Oncology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Oncology
GA DL2DW
UT WOS:000375444200018
PM 26976986
DA 2026-07-24
ER

PT J
AU Palmieri, B
   Vadalà, M
   Laurino, C
AF Palmieri, Beniamino
   Vadala, Maria
   Laurino, Carmen
TI Electromedical devices in wound healing management: a narrative review
SO JOURNAL OF WOUND CARE
LA English
DT Review
DE biophotonic therapy; electromedical devices; electrotherapy; PEMF;
   phototherapy; pressure therapy; wound healing
ID LEVEL LASER THERAPY; INTERMITTENT PNEUMATIC COMPRESSION;
   ELECTROMAGNETIC-FIELD THERAPY; VENOUS LEG ULCERS;
   ELECTRICAL-STIMULATION; LIGHT THERAPY; FREQUENCY ULTRASOUND; PRESSURE
   ULCERS; PULSED CURRENT; GROWTH-FACTOR
AB Wound healing is the sum of physiological sequential steps, leading to skin restoration. However, in some conditions, such as diabetes, pressure ulcers (PU) and venous legs ulcers (VLU), healing is a major challenge and requires multiple strategies. In this context, some electromedical devices may accelerate and/or support wound healing, modulating the inflammatory, proliferation (granulation) and tissue-remodelling phases. This review describes some helpful electromedical devices including: ultrasonic-assisted wound debridement; electrotherapy; combined ultrasound and electric field stimulation; low-frequency pulsed electromagnetic fields; phototherapy (for example, laser therapy and light-emitting diode (LED) therapy); biophotonic therapies, and pressure therapies (for example, negative pressure wound therapy, and high pressure and intermittent pneumatic compression) The review focuses on the evidence-based medicine and adequate clinical trial design in relation to these devices.
C1 [Palmieri, Beniamino; Vadala, Maria; Laurino, Carmen] Univ Modena & Reggio Emilia, Dept Gen Surg & Surg Specialties, Surg Clin, Med Sch, Via Pozzo 71, I-41124 Modena, Italy.
   [Palmieri, Beniamino; Vadala, Maria; Laurino, Carmen] Second Opin Med Network, Via Ciro Bisi 125, Modena, Italy.
C3 Universita di Modena e Reggio Emilia
RP Vadalà, M (通讯作者)，Univ Modena & Reggio Emilia, Dept Gen Surg & Surg Specialties, Surg Clin, Med Sch, Via Pozzo 71, I-41124 Modena, Italy.; Vadalà, M (通讯作者)，Second Opin Med Network, Via Ciro Bisi 125, Modena, Italy.
EM mary.vadala@gmail.com
RI /K-3886-2016
CR AlGhamdi KM, 2012, LASER MED SCI, V27, P237, DOI 10.1007/s10103-011-0885-2
   Alhede M, 2014, ADV APPL MICROBIOL, V86, P1, DOI 10.1016/B978-0-12-800262-9.00001-9
   Alvarez OM, 2015, WOUNDS, V27, P293
   Aragona S E, 2017, J Biol Regul Homeost Agents, V31, P213
   Arany PR, 2007, WOUND REPAIR REGEN, V15, P866, DOI 10.1111/j.1524-475X.2007.00306.x
   Araujo RD, 2018, LASER MED SCI, V33, P103, DOI 10.1007/s10103-017-2354-z
   Avci P, 2013, SEMIN CUTAN MED SURG, V32, P41
   Avrahami R, 2015, WOUNDS, V27, P199
   Bogie KM, 2000, ASSIST TECHNOL, V12, P50, DOI 10.1080/10400435.2000.10132009
   Bradley M, 1999, Health Technol Assess, V3, piii
   Breuing KH, 2005, ANN PLAS SURG, V55, P183, DOI 10.1097/01.sap.0000168695.20350.07
   Brizhik L, 2009, ELECTROMAGN BIOL MED, V28, P15, DOI 10.1080/15368370802708223
   Broughton G, 2006, PLAST RECONSTR SURG, V117, p12S, DOI 10.1097/01.prs.0000225430.42531.c2
   Caetano KS, 2009, PHOTOMED LASER SURG, V27, P111, DOI 10.1089/pho.2008.2398
   Campos ACL, 2008, CURR OPIN CLIN NUTR, V11, P281, DOI 10.1097/MCO.0b013e3282fbd35a
   Carmen John C., 2004, Journal of Infection and Chemotherapy, V10, P193
   de Sousa APC, 2011, PHOTOMED LASER SURG, V29, P605, DOI 10.1089/pho.2010.2833
   Chao PHG, 2007, CONNECT TISSUE RES, V48, P188, DOI 10.1080/03008200701424451
   COSTERTON JW, 1995, J IND MICROBIOL, V15, P137, DOI 10.1007/BF01569816
   Da Silva AA, 2013, J COSMET LASER THER, V15, P210, DOI 10.3109/14764172.2012.761345
   Chaves MED, 2014, AN BRAS DERMATOL, V89, P616, DOI 10.1590/abd1806-4841.20142519
   DEATON W R Jr, 1957, Am Surg, V23, P278
   Delis KT, 2005, J VASC SURG, V42, P717, DOI 10.1016/j.jvs.2005.06.004
   Dolibog P, 2013, OSTOMY WOUND MANAG, V59, P22
   Doughty Dorothy B, 2004, Home Healthc Nurse, V22, P264, DOI 10.1097/00004045-200404000-00014
   Dumville JC, 2015, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011354.pub2
   Durovic A, 2008, VOJNOSANIT PREGL, V65, P906
   Dwivedi MK, 2016, J WOUND CARE, V25, P199, DOI 10.12968/jowc.2016.25.4.199
   Enwemeka CS, 2004, PHOTOMED LASER SURG, V22, P323, DOI 10.1089/pho.2004.22.323
   Fraccalvieri M, 2015, INT WOUND J, V12, P669, DOI 10.1111/iwj.12194
   Guerriero Fabio, 2015, Case Rep Dermatol Med, V2015, P576580, DOI [10.1155/2015/576580, 10.1155/2015/576580]
   Guo S, 2010, J DENT RES, V89, P219, DOI 10.1177/0022034509359125
   Gupta A, 2009, NEUROL INDIA, V57, P622, DOI 10.4103/0028-3886.57820
   Haesler E., 2014, Prev Treat Press Ulcers: Quick Ref Guide
   Hall-Stoodley L, 2004, NAT REV MICROBIOL, V2, P95, DOI 10.1038/nrmicro821
   Hess CL, 2003, ANN PLAS SURG, V51, P210, DOI 10.1097/01.SAP.0000058513.10033.6B
   Johnson KE, 2014, ADV WOUND CARE, V3, P647, DOI 10.1089/wound.2013.0517
   Jünger M, 2008, WOUND REPAIR REGEN, V16, P480, DOI 10.1111/j.1524-475X.2008.00393.x
   Karu T, 2011, IUBMB LIFE, V63, P747, DOI 10.1002/iub.514
   Karu TI, 2010, IUBMB LIFE, V62, P607, DOI 10.1002/iub.359
   Kavros SJ, 2018, ADV SKIN WOUND CARE, V31, P55, DOI 10.1097/01.ASW.0000527967.10613.87
   Kitajo K, 2003, PHYS REV LETT, V90, DOI 10.1103/PhysRevLett.90.218103
   Kloth Luther C, 2005, Int J Low Extrem Wounds, V4, P23
   KUBASOVA T, 1995, IMMUNOL CELL BIOL, V73, P239, DOI 10.1038/icb.1995.39
   Kwan RLC, 2015, ADV SKIN WOUND CARE, V28, P212, DOI 10.1097/01.ASW.0000462012.58911.53
   Labropoulos N, 2005, J VASC SURG, V42, P710, DOI 10.1016/j.jvs.2005.05.051
   Landau Z, 2011, PHOTOMED LASER SURG, V29, P399, DOI 10.1089/pho.2010.2858
   Landén NX, 2016, CELL MOL LIFE SCI, V73, P3861, DOI 10.1007/s00018-016-2268-0
   Lee YN, 2017, J WOUND OSTOMY CONT, V44, P517, DOI 10.1097/WON.0000000000000378
   Leite SN, 2014, AN BRAS DERMATOL, V89, P899, DOI 10.1590/abd1806-4841.20143356
   MEHLSEN J, 1993, ANGIOLOGY, V44, P16, DOI 10.1177/000331979304400103
   Meszaros AJ, 2000, J IMMUNOL, V165, P435, DOI 10.4049/jimmunol.165.1.435
   Miller C, 2017, J WOUND CARE, V26, P88, DOI 10.12968/jowc.2017.26.3.88
   Mittermayr R, 2007, MOL MED, V13, P22, DOI 10.2119/2006-00035.Mittermayr
   Montagnier L, 2009, INTERDISCIP SCI, V1, P81, DOI 10.1007/s12539-009-0036-7
   Moulin VJ, 2012, ADV WOUND CARE, V1, P81, DOI 10.1089/wound.2011.0318
   Nelson EA, 2014, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001899.pub4
   NEMETH AJ, 1993, DERMATOL CLIN, V11, P783, DOI 10.1016/S0733-8635(18)30231-6
   Nikolovska S, 2005, MED SCI MONITOR, V11, pCR337
   Nobuta S, 2008, UPSALA J MED SCI, V113, P181, DOI 10.3109/2000-1967-228
   Norgren L, 2007, J ENDOVASC THER, V14, P743, DOI 10.1583/1545-1550(2007)14[743:TISFOR]2.0.CO;2
   Achar RAN, 2014, ACTA CIR BRAS, V29, P125, DOI 10.1590/S0102-86502014000200009
   Ortiz LA, 2017, NUTR CLIN PRACT, V32, P508, DOI 10.1177/0884533617701402
   Pallotta RC, 2012, LASER MED SCI, V27, P71, DOI 10.1007/s10103-011-0906-1
   Polak A, 2016, J WOUND CARE, V25, P742, DOI 10.12968/jowc.2016.25.12.742
   Polak A, 2017, PHYS THER, V97, P777, DOI 10.1093/ptj/pzx052
   Posten W, 2005, DERMATOL SURG, V31, P334, DOI 10.1097/00042728-200503000-00016
   Prindeze NJ, 2012, EXP BIOL MED, V237, P1241, DOI 10.1258/ebm.2012.012180
   PROVOST P, 1994, ARTERIOSCLER THROMB, V14, P331, DOI 10.1161/01.ATV.14.3.331
   Qian Z, 1999, J BIOMED MATER RES, V44, P198, DOI 10.1002/(SICI)1097-4636(199902)44:2<198::AID-JBM10>3.0.CO;2-P
   Qing C, 2017, CHIN J TRAUMATOL, V20, P189, DOI 10.1016/j.cjtee.2017.06.001
   RAFFL AB, 1952, ANN SURG, V136, P1048, DOI 10.1097/00000658-195212000-00022
   Reddy M, 2006, JAMA-J AM MED ASSOC, V296, P974, DOI 10.1001/jama.296.8.974
   Romanelli M, 2017, DRUG DES DEV THER, V11, P3551, DOI 10.2147/DDDT.S142580
   Rowland J, 2000, AUST NZ J SURG, V70, P110, DOI 10.1046/j.1440-1622.2000.01766.x
   Schultz GS, 2003, WOUND REPAIR REGEN, V11, pS1, DOI 10.1046/j.1524-475X.11.s2.1.x
   Seeliger C, 2014, EUR J MED RES, V19, DOI 10.1186/2047-783X-19-37
   Sharif MO, 2015, DENT TRAUMATOL, V31, P422, DOI 10.1111/edt.12227
   SIEGMANIGRA Y, 1990, SCAND J INFECT DIS, V22, P633, DOI 10.3109/00365549009027114
   Singer AJ, 1999, NEW ENGL J MED, V341, P738, DOI 10.1056/NEJM199909023411006
   Stebbins WG, 2016, J AM ACAD DERMATOL, V75, pE71, DOI 10.1016/j.jaad.2016.02.1238
   STILLER MJ, 1992, BRIT J DERMATOL, V127, P147, DOI 10.1111/j.1365-2133.1992.tb08047.x
   Tewarie L, 2015, EUR J CARDIO-THORAC, V47, pE180, DOI 10.1093/ejcts/ezv007
   Ud-Din S, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0124502
   Wagner F W Jr, 1981, Foot Ankle, V2, P64
   Wang HT, 2017, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011979.pub2
   ZEITLER E, 1985, FORTSCHR RONTG NEUEN, V142, P275, DOI 10.1055/s-2008-1052648
   Zeng FG, 2000, BRAIN RES, V869, P251, DOI 10.1016/S0006-8993(00)02475-6
   Zhevago NA, 2006, PHOTOMED LASER SURG, V24, P129, DOI 10.1089/pho.2006.24.129
NR 89
TC 8
Z9 14
U1 1
U2 42
PU MA HEALTHCARE LTD
PI LONDON
PA ST JUDES CHURCH, DULWICH ROAD, LONDON SE24 0PB, ENGLAND
SN 0969-0700
EI 2052-2916
J9 J WOUND CARE
JI J. Wound Care
PD JUL
PY 2020
VL 29
IS 7
BP 408
EP 418
DI 10.12968/jowc.2020.29.7.408
PG 11
WC Dermatology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Dermatology
GA MN3VX
UT WOS:000550773300006
PM 32654604
DA 2026-07-24
ER

PT J
AU Krpata, DM
AF Krpata, David M.
TI Wound Closure and Management
SO SURGICAL INFECTIONS
LA English
DT Article; Proceedings Paper
CT 38th Annual Meeting of the Surgical-Infection-Society
CY APR 22-26, 2018
CL Westlake Village, CA
SP Surg Infect Soc
DE fascial closure; skin closure; wound closure; wound management
ID SURGICAL SITE INFECTIONS; SKIN CLOSURE; DELAYED PRIMARY; SUBCUTICULAR
   SUTURES; ABDOMINAL-SURGERY; OPEN-LABEL; MULTICENTER; METAANALYSIS;
   STAPLES; STITCH
AB Background: The management of incisions and decisions on closure techniques for surgical wounds are driven by expected incisional morbidity and the severity of the potential morbidity for the patient. Methods: This article reviews current literature on the potential strategies to be considered in closing the skin and fascia of incisions. Results: The review of the literature indicates that low-risk wounds for infection should be closed primarily with subcuticular suture, and adjunctive local measures should be avoided. Adjunctive measures of irrigation, topical antimicrobial agents, and negative pressure incisional therapy may have a role in high-risk wounds. Surgeons should strongly consider primary closure of contaminated wounds. Conclusions: The overall literature on adjuncts of wound irrigation, topical antimicrobials, and negative pressure wound therapy have potential to be of benefit but additional investigation is necessary since they do impact cost, patient experience, and antibiotic stewardship.
C1 [Krpata, David M.] Cleveland Clin Fdn, Comprehens Hernia Ctr, Digest Dis & Surg Inst, 9500 Euclid Ave,A-100, Cleveland, OH 44195 USA.
C3 Cleveland Clinic Foundation
RP Krpata, DM (通讯作者)，Cleveland Clin Fdn, Comprehens Hernia Ctr, Digest Dis & Surg Inst, 9500 Euclid Ave,A-100, Cleveland, OH 44195 USA.
EM krpatad@ccf.org
CR [Anonymous], COCHRANE DATABASE SY
   Bhangu A, 2013, JAMA SURG, V148, P779, DOI 10.1001/jamasurg.2013.2336
   Deerenberg EB, 2015, LANCET, V386, P1254, DOI 10.1016/S0140-6736(15)60459-7
   Duttaroy DD, 2009, SURG INFECT, V10, P129, DOI 10.1089/sur.2007.030
   He JC, 2017, SURG INFECT, V18, P431, DOI 10.1089/sur.2017.018
   Heal CF, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011426.pub2
   Imamura K, 2016, J GASTROINTEST SURG, V20, P2083, DOI 10.1007/s11605-016-3283-z
   Kobayashi S, 2015, BRIT J SURG, V102, P495, DOI 10.1002/bjs.9786
   Krishnan R, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2015-009257
   Millbourn D, 2009, ARCH SURG-CHICAGO, V144, P1056, DOI 10.1001/archsurg.2009.189
   Mueller TC, 2015, LANGENBECK ARCH SURG, V400, P167, DOI 10.1007/s00423-015-1279-x
   RUSSELL GG, 1990, J BONE JOINT SURG BR, V72, P125, DOI 10.1302/0301-620X.72B1.2298770
   Schweizer ML, 2014, JAMA SURG, V149, P575, DOI 10.1001/jamasurg.2013.4663
   Siribumrungwong B, 2018, ANN SURG, V267, P631, DOI 10.1097/SLA.0000000000002464
   Smack DP, 1996, JAMA-J AM MED ASSOC, V276, P972, DOI 10.1001/jama.276.12.972
   Strugala V, 2017, SURG INFECT, V18, P810, DOI 10.1089/sur.2017.156
   Tsujinaka T, 2013, LANCET, V382, P1105, DOI 10.1016/S0140-6736(13)61780-8
NR 17
TC 2
Z9 3
U1 0
U2 17
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1096-2964
EI 1557-8674
J9 SURG INFECT
JI Surg. Infect.
PD FEB
PY 2019
VL 20
IS 2
SI SI
BP 135
EP 138
DI 10.1089/sur.2018.235
EA DEC 2018
PG 4
WC Infectious Diseases; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
SC Infectious Diseases; Surgery
GA HS5PZ
UT WOS:000452714200001
PM 30526404
DA 2026-07-24
ER

PT J
AU Foroulis, CN
   Karapanagiotidis, G
   Papakonstantinou, C
AF Foroulis, Christophoros N.
   Karapanagiotidis, Georgios
   Papakonstantinou, Christos
TI Pericardial Patch Tracheoplasty for the Repair of a Long, Multisegmental
   Postintubation Tracheal Damage
SO ARTIFICIAL ORGANS
LA English
DT Article
DE Tracheal stenosis; Tracheoplasty; Pericardial patch
ID REPLACEMENT; STENOSIS; DEFECTS
AB A 64-year-old man was admitted with a postintubation, multisegmental tracheal damage comprising of two stenotic lesions, below and above a tracheotomy. The patient underwent resection of the damaged anterolateral tracheal wall through a combined collar-cuff and median sternotomy incision and tracheoplasty with autologous pericardium around a Silastic T-tube that was fixed to the cricoid cartilage, healthy distal trachea, and the remaining membranous wall. The postoperative period was complicated with a deep sternal wound infection that was successfully treated with vacuum-assisted closure for 2 weeks. Removal of the T-tube 9 months later resulted in a patent and well-functioning airway. Pericardial patch tracheoplasty and T-tube stenting of the repair for several months is a good alternative to extended tracheal resection for the treatment of the rare long, postintubation multisegmental tracheal damage. The pericardial patch is highly resistant to infection and allows the formation of a neotrachea.
C1 [Foroulis, Christophoros N.; Karapanagiotidis, Georgios; Papakonstantinou, Christos] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Dept Thorac & Cardiovasc Surg, Sch Med, Thessaloniki 54636, Greece.
C3 Aristotle University of Thessaloniki; Ahepa University Hospital
RP Foroulis, CN (通讯作者)，Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Dept Thorac & Cardiovasc Surg, Sch Med, 1 Stilponos Kiriakidi St, Thessaloniki 54636, Greece.
EM cforoulis@otenet.gr
RI Foroulis, Christophoros/ABD-9464-2021
OI Foroulis, Christophoros/0000-0002-5708-7210; Karapanagiotidis,
   Georgios/0000-0002-2065-7646
CR Abbasidezfouli A, 2007, ANN THORAC SURG, V84, P211, DOI 10.1016/j.athoracsur.2007.03.050
   Bando K, 1996, ANN THORAC SURG, V62, P981, DOI 10.1016/0003-4975(96)00478-X
   BRYANT LR, 1964, J THORAC CARDIOV SUR, V48, P733, DOI 10.1016/S0022-5223(19)33356-2
   Cheng ATL, 1997, ARCH OTOLARYNGOL, V123, P1069
   Foroulis Christophoros N, 2003, Interact Cardiovasc Thorac Surg, V2, P595, DOI 10.1016/S1569-9293(03)00142-7
   Grillo HC, 2002, ANN THORAC SURG, V73, P1995, DOI 10.1016/S0003-4975(02)03564-6
   GRILLO HC, 1990, EUR J CARDIO-THORAC, V4, P573, DOI 10.1016/1010-7940(90)90149-T
   TOCEWICZ K, 1993, EUR J CARDIO-THORAC, V7, P101, DOI 10.1016/1010-7940(93)90189-I
NR 8
TC 2
Z9 3
U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0160-564X
J9 ARTIF ORGANS
JI Artif. Organs
PD SEP
PY 2012
VL 36
IS 9
BP 835
EP 839
DI 10.1111/j.1525-1594.2011.01435.x
PG 5
WC Engineering, Biomedical; Transplantation
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Engineering; Transplantation
GA 003EL
UT WOS:000308590900014
PM 22428774
DA 2026-07-24
ER

PT J
AU Siracuse, JJ
   Saillant, NN
   Hauser, CJ
AF Siracuse, J. J.
   Saillant, N. N.
   Hauser, C. J.
TI Technological advancements in the care of the trauma patient
SO EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
LA English
DT Review
DE Abdominal trauma; Pelvic trauma; Polytrauma; Vascular trauma
ID EXTRAVASCULAR LUNG WATER; RENAL REPLACEMENT THERAPY; VACUUM-ASSISTED
   CLOSURE; EXTRACORPOREAL MEMBRANE-OXYGENATION; INTERMACS
   INTERVAL-ANALYSIS; MORTALITY-RATES CORRELATE; PULMONARY-ARTERY CATHETER;
   RANDOMIZED CLINICAL-TRIAL; COMPLEX HEPATIC INJURIES; RAPID VOLUME
   REPLACEMENT
AB Medical technology has benefited many types of patients, but trauma care has arguably benefited more from technologic development than almost any other field.
   A literature review to identify key technological advances in the care of trauma patients was performed.
   The advances in trauma care are in great measure due to the integration of many different systems. Medical technology impacts care in the field at the site of the trauma, in the transport to trauma facilities, and care at the trauma center itself. Once at the hospital, technology has impacted care in the trauma bay, intensive care units, the operating room, and in postoperative and long-term care settings. The integration of advancements, however, needs to be examined in a careful systematic fashion to insure that patients will actually derive benefit.
C1 [Siracuse, J. J.; Saillant, N. N.; Hauser, C. J.] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Acute Care Surg, Boston, MA 02215 USA.
C3 Harvard University; Harvard Medical School; Harvard University Medical
   Affiliates; Beth Israel Deaconess Medical Center
RP Hauser, CJ (通讯作者)，Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Acute Care Surg, 110 Francis St, Boston, MA 02215 USA.
EM cjhauser@bidmc.harvard.edu
RI Hauser, Carl/Y-1189-2019; Siracuse, Jeffrey/HRC-5695-2023
OI Hauser, Carl/0000-0003-3167-1846; Saillant, Noelle/0000-0002-8905-0682; 
CR Ahmed N, 2005, J AM COLL SURGEONS, V201, P213, DOI 10.1016/j.jamcollsurg.2005.04.021
   Arlt M, 2011, EUR J CARDIO-THORAC, V40, P689, DOI 10.1016/j.ejcts.2010.12.055
   Arnal JM, 2008, INTENS CARE MED, V34, P75, DOI 10.1007/s00134-007-0847-0
   Asensio JA, 2003, J TRAUMA, V54, P647, DOI 10.1097/01.TA.0000054647.59217.BB
   Berton C, 2002, CRIT CARE, V6, P216, DOI 10.1186/cc1492
   Bledsoe BE, 2006, J TRAUMA, V60, P1257, DOI 10.1097/01.ta.0000196489.19928.c0
   Bowersox JC, 1996, J VASC SURG, V23, P281, DOI 10.1016/S0741-5214(96)70272-0
   Bowersox JC, 1998, J AM COLL SURGEONS, V186, P615, DOI 10.1016/S1072-7515(98)00105-7
   BOYD CR, 1989, J TRAUMA, V29, P789, DOI 10.1097/00005373-198906000-00015
   Brathwaite CEM, 1998, J TRAUMA, V45, P140, DOI 10.1097/00005373-199807000-00029
   Britt LD, 2009, J AM COLL SURGEONS, V208, P753
   Brown LM, 2009, AM J PHYSIOL-LUNG C, V297, pL547, DOI 10.1152/ajplung.00127.2009
   Brundage SI, 2001, J TRAUMA, V51, P1054, DOI 10.1097/00005373-200112000-00005
   Burchell SA, 1997, CRIT CARE MED, V25, P388, DOI 10.1097/00003246-199703000-00003
   Burns KEA, 2008, INTENS CARE MED, V34, P1757, DOI 10.1007/s00134-008-1154-0
   Carobbi A, 2010, SURG ENDOSC, V24, P1325, DOI 10.1007/s00464-009-0768-9
   Chaney JC, 2002, CRIT CARE MED, V30, P2338, DOI 10.1097/00003246-200210000-00025
   Chatburn Robert L, 2004, Respir Care, V49, P507
   Chen YS, 2008, LANCET, V372, P554, DOI 10.1016/S0140-6736(08)60958-7
   Choy PY, 2007, COCHRANE DB SYST REV, V18
   Connors AF, 1996, JAMA-J AM MED ASSOC, V276, P889, DOI 10.1001/jama.276.11.889
   Cunningham P, 1997, J TRAUMA, V43, P940, DOI 10.1097/00005373-199712000-00013
   DAIGLE RE, 1975, J APPL PHYSIOL, V38, P1153, DOI 10.1152/jappl.1975.38.6.1153
   DeFranzo AJ, 2008, PLAST RECONSTR SURG, V121, P832, DOI 10.1097/01.prs.0000299268.51008.47
   Demetriades D, 2005, ANN SURG, V242, P512, DOI 10.1097/01.sla.0000184169.73614.09
   Demetriades D, 2002, J TRAUMA, V52, P117, DOI 10.1097/00005373-200201000-00020
   Dojat M, 2000, AM J RESP CRIT CARE, V161, P1161, DOI 10.1164/ajrccm.161.4.9904064
   Duchesne JC, 2008, J TRAUMA, V64, P92, DOI 10.1097/TA.0b013e31815dd4c4
   DUNHAM CM, 1991, SURG GYNECOL OBSTET, V173, P179
   Dyer D, 2008, J TRAUMA, V65, P1209, DOI 10.1097/TA.0b013e3181878052
   Eachempati SR, 2007, J TRAUMA, V63, P987, DOI 10.1097/TA.0b013e3181574930
   FALCONE RE, 1989, ANGIOLOGY, V40, P964, DOI 10.1177/000331978904001105
   Fang JC, 2009, NEW ENGL J MED, V361, P2282, DOI 10.1056/NEJMe0910394
   Fitzpatrick JR, 2011, CIRC J, V75, P38, DOI 10.1253/circj.CJ-10-1091
   Fu CY, 2010, AM J EMERG MED
   Gan TJ, 2002, ANESTHESIOLOGY, V97, P820, DOI 10.1097/00000542-200210000-00012
   Hadian M, 2005, CRIT CARE, V9, pE7, DOI 10.1186/cc3716
   Haneya A, 2011, ANN THORAC SURG, V91, P250, DOI 10.1016/j.athoracsur.2010.09.005
   Hauser CJ, 1996, SURG ENDOSC-ULTRAS, V10, P694, DOI 10.1007/BF00188533
   HAUSER CJ, 1989, ARCH SURG-CHICAGO, V124, P291
   HAUSER CJ, 1987, ARCH SURG-CHICAGO, V122, P1112
   Heniford BT, 2001, SURG ENDOSC-ULTRAS, V15, P799, DOI 10.1007/s004640080025
   Hess JR, 2008, J TRAUMA, V65, P748, DOI 10.1097/TA.0b013e3181877a9c
   Holman WL, 2009, J AM COLL SURGEONS, V208, P755, DOI 10.1016/j.jamcollsurg.2008.11.016
   Hope WW, 2009, INJURY, V40, P564, DOI 10.1016/j.injury.2008.01.024
   Isakow W, 2006, AM J PHYSIOL-LUNG C, V291, pL1118, DOI 10.1152/ajplung.00277.2006
   Johnson Chatt A, 2010, Semin Intervent Radiol, V27, P38, DOI 10.1055/s-0030-1247887
   Kim P, 2004, CAN J SURG, V47, P295
   Kirklin JK, 2011, J HEART LUNG TRANSPL, V30, P115, DOI 10.1016/j.healun.2010.12.001
   Kotake Y, 2003, ANESTHESIOLOGY, V99, P283, DOI 10.1097/00000542-200308000-00009
   Kuzkov VV, 2006, CRIT CARE MED, V34, P1647, DOI 10.1097/01.CCM.0000218817.24208.2E
   Kwon AH, 2001, EUR J SURG, V167, P316
   Labler L, 2009, J TRAUMA, V66, P749, DOI 10.1097/TA.0b013e318171971a
   Laurent A, 2005, DIS COLON RECTUM, V48, P729, DOI 10.1007/s10350-004-0829-z
   Lellouche F, 2006, AM J RESP CRIT CARE, V174, P894, DOI 10.1164/rccm.200511-1780OC
   Leppäniemi R, 2003, J TRAUMA, V55, P636, DOI 10.1097/01.TA.0000063000.05274.A4
   Lietz K, 2010, J CARDIAC SURG, V25, P462, DOI 10.1111/j.1540-8191.2010.01050.x
   Lins RL, 2009, NEPHROL DIAL TRANSPL, V24, P512, DOI 10.1093/ndt/gfn560
   LUJANMOMPEAN JA, 1995, SURG ENDOSC-ULTRAS, V9, P879
   Macario A, 2008, SURG INNOV, V15, P284, DOI 10.1177/1553350608324933
   Mallat AF, 2008, AM SURGEON, V74, P1166
   Marasco SF, 2008, HEART LUNG CIRC, V17, pS41, DOI 10.1016/j.hlc.2008.08.009
   Marcello PW, 2006, SURG ENDOSC, V20, P263, DOI 10.1007/s00464-005-0258-7
   MARSHALL JC, 1995, CRIT CARE MED, V23, P1638, DOI 10.1097/00003246-199510000-00007
   Martin GS, 2005, CRIT CARE, V9, pR74, DOI 10.1186/cc3025
   Matthews BD, 2003, SURG ENDOSC, V17, P254, DOI 10.1007/s00464-002-8831-9
   McBeth PB, 2010, J TRAUMA, V69, P1597, DOI 10.1097/TA.0b013e3181e61ea9
   McKenney MG, 2009, J AM COLL SURGEONS, V208, P750, DOI 10.1016/j.jamcollsurg.2009.01.036
   Meredith JW, 2009, J AM COLL SURGEONS, V208, P761
   Michard F, 2003, CHEST, V124, P1900, DOI 10.1378/chest.124.5.1900
   Minne L, 2008, CRIT CARE, V12, DOI 10.1186/cc7160
   MITCHELL JP, 1992, AM REV RESPIR DIS, V145, P990, DOI 10.1164/ajrccm/145.5.990
   Mohr AM, 2003, J TRAUMA, V55, P1077, DOI 10.1097/01.TA.0000100219.02085.AB
   Monnet X, 2010, CRIT CARE, V14, DOI 10.1186/cc9058
   MORRIS AH, 1994, AM J RESP CRIT CARE, V149, P295, DOI 10.1164/ajrccm.149.2.8306022
   Mutoh T, 2009, STROKE, V40, P2368, DOI 10.1161/STROKEAHA.109.547463
   NICHOLL JP, 1995, BMJ-BRIT MED J, V311, P217, DOI 10.1136/bmj.311.6999.217
   Olson CJ, 2003, J TRAUMA, V55, P45, DOI 10.1097/01.TA.0000071291.17287.57
   Oz MC, 2003, J CARDIAC SURG, V18, P486, DOI 10.1046/j.0886-0440.2003.00302.x
   Oz MC, 2000, ANN THORAC SURG, V69, P1376, DOI 10.1016/S0003-4975(00)01194-2
   Peek GJ, 2009, LANCET, V374, P1351, DOI 10.1016/S0140-6736(09)61069-2
   Pereira S, 2000, SURGERY, V128, P678, DOI 10.1067/msy.2000.108219
   Pryor HI, 2008, FRONT BIOSCI-LANDMRK, V13, P2140, DOI 10.2741/2830
   Rauf Anis Abdul, 2008, J Intensive Care Med, V23, P195, DOI 10.1177/0885066608315743
   Rispoli DM, 2010, J TRAUMA, V68, P1247, DOI 10.1097/TA.0b013e3181d3cc3c
   Rogers FB, 2001, J TRAUMA, V51, P1037, DOI 10.1097/00005373-200112000-00002
   Romano F, 2002, SURG ENDOSC, V16, P1608, DOI 10.1007/s00464-001-9145-z
   Romano F, 2007, J LAPAROENDOSC ADV S, V17, P763, DOI 10.1089/lap.2007.0005
   Rose EA, 2001, NEW ENGL J MED, V345, P1435, DOI 10.1056/NEJMoa012175
   Rousseau H, 2011, CARDIOVASC INTERVENT
   Sabel M, 2004, EUR SPINE J, V13, pS97, DOI 10.1007/s00586-004-0735-z
   Sagraves S, 2008, J TRAUMA, V64, P97
   SATIANI B, 1987, ARCH SURG-CHICAGO, V122, P1044
   Satiani B, 1988, Ann Vasc Surg, V2, P37, DOI 10.1016/S0890-5096(06)60775-9
   Scherer SS, 2008, PLAST RECONSTR SURG, V122, P786, DOI 10.1097/PRS.0b013e31818237ac
   SCHILLER WR, 1988, J TRAUMA, V28, P1127, DOI 10.1097/00005373-198808000-00004
   Sechser A, 2001, Clin Liver Dis, V5, P415, DOI 10.1016/S1089-3261(05)70172-0
   Shin TG, 2011, CRIT CARE MED, V39, P1, DOI 10.1097/CCM.0b013e3181feb339
   SHOEMAKER WC, 1990, ARCH SURG-CHICAGO, V125, P1332
   Slaughter MS, 2009, NEW ENGL J MED, V361, P2241, DOI 10.1056/NEJMoa0909938
   Slutsky A S, 2000, Respir Res, V1, P73, DOI 10.1186/rr15
   SNOWDEN S, 1993, MED INFORM, V18, P367, DOI 10.3109/14639239309025325
   Strode CA, 2003, ACAD EMERG MED, V10, P1411, DOI 10.1197/S1069-6563(03)00547-5
   Swartz RD, 2005, CLIN NEPHROL, V63, P335
   Taylor RW, 1997, CRIT CARE MED, V25, P2064, DOI 10.1097/00003246-199712000-00028
   The Trauma Center Association of America, TRAUM GOLD HOUR
   Theologou Thomas, 2011, Cochrane Database Syst Rev, pCD004472, DOI 10.1002/14651858.CD004472.pub3
   Thiagarajan RR, 2009, ANN THORAC SURG, V87, P778, DOI 10.1016/j.athoracsur.2008.12.079
   Tomizawa Yasuko, 2005, J Artif Organs, V8, P137, DOI 10.1007/s10047-005-0296-x
   TRAN DD, 1994, NEPHROL DIAL TRANSPL, V9, P121
   URANUS S, 1994, AM J SURG, V168, P49, DOI 10.1016/S0002-9610(05)80070-4
   van Heerden PV, 2000, ANAESTH INTENS CARE, V28, P427, DOI 10.1177/0310057X0002800412
   Velmahos GC, 2002, J TRAUMA, V53, P303, DOI 10.1097/00005373-200208000-00019
   Verbeek D, 2008, WORLD J SURG, V32, P1874, DOI 10.1007/s00268-008-9591-z
   Wong YC, 2000, J TRAUMA, V49, P71, DOI 10.1097/00005373-200007000-00010
   Zannis J, 2009, ANN PLAS SURG, V62, P407, DOI 10.1097/SAP.0b013e3181881b29
   ZAPOL WM, 1979, JAMA-J AM MED ASSOC, V242, P2193, DOI 10.1001/jama.242.20.2193
NR 117
TC 5
Z9 9
U1 0
U2 6
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 1863-9933
EI 1863-9941
J9 EUR J TRAUMA EMERG S
JI Eur. J. Trauma Emerg. Surg.
PD JUN
PY 2012
VL 38
IS 3
BP 241
EP 251
DI 10.1007/s00068-011-0160-z
PG 11
WC Emergency Medicine
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine
GA 953GP
UT WOS:000304855300005
PM 26815955
OA Bronze
DA 2026-07-24
ER

PT J
AU Chauhan, S
   Gulia, M
   Singh, RP
   Jhawat, V
AF Chauhan, Sunita
   Gulia, Monika
   Singh, Rahul Pratap
   Jhawat, Vikas
TI Diabetic Wound: Pathophysiology, Complications and Treatment Strategies
SO CURRENT PROTEIN & PEPTIDE SCIENCE
LA English
DT Review
DE Diabetic complications; diabetic wound; Insulin; topical delivery; PLO
   gel; wound-healing
ID VACUUM-ASSISTED CLOSURE; FOOT ULCERS; THERAPY; NEOVASCULARIZATION;
   EXPRESSION
AB Diabetic wound healing is expected to affect 25% of all diabetics, resulting in less severe external factors, economic costs, and less trauma. Topical formulations have been continually improved to achieve a range of amazing properties and have had a significant impact on the management of diabetic wounds. Topical insulin has become one of the most attractive and convenient wound healing techniques due to its excellent biocompatibility, water retention, and therapeutic properties. Multiple versatile topical insulins have been identified and have shown promise over the past few years as they greatly facilitate the management of diabetic wounds as we understand their etiology. The physiological wound healing process repairs damaged tissue and restores skin integrity. For about a century, insulin, a powerful healing agent, and it has been utilized in several clinical and experimental researches research studies to accelerate the healing of various injuries.
C1 [Chauhan, Sunita; Gulia, Monika; Singh, Rahul Pratap; Jhawat, Vikas] GD Goenka Univ, Sch Med & Allied Sci, Dept Pharmaceut Sci, Gurugram, Haryana, India.
C3 GD Goenka University
RP Jhawat, V (通讯作者)，GD Goenka Univ, Sch Med & Allied Sci, Dept Pharmaceut Sci, Gurugram, Haryana, India.
EM jhawat231287@gmail.com
RI Singh, Rahul Pratap/B-6226-2016; Jhawat, Vikas/AAA-5823-2020; Gulia,
   Monika/AAU-3680-2021
OI Singh, Rahul Pratap/0000-0001-6807-0484; Jhawat,
   Vikas/0000-0002-5106-9636; Gulia, Monika/0000-0002-7114-4904
CR Abdelaal MAZ, 2015, Technological Advances in Surgery, Trauma and Critical Care, P563, DOI 10.1007/978-1-4939-2671-8_46
   Bain Michael A, 2020, J Comp Eff Res, V9, P691, DOI [10.2217/cer-2020-0058, 10.2217/cer-2020-0058]
   Belgamwar VS., 2014, J. Pharm, V2
   Cai Y, 2022, WORLD J DIABETES, V13, P926, DOI 10.4239/wjd.v13.i11.926
   Cam ME, 2021, MAT SCI ENG C-MATER, V119, DOI 10.1016/j.msec.2020.111586
   Catrina SB, 2016, DIABETES-METAB RES, V32, P179, DOI 10.1002/dmrr.2742
   Caturano A, 2023, CURR ISSUES MOL BIOL, V45, P6651, DOI 10.3390/cimb45080420
   Chaudhary N, 2018, International Journal of Research and Development in Pharmacy and Life Sciences, V7, P3030, DOI [10.21276/ijrdpl.2278-0238.2018.7(4).3030-3033, 10.21276/IJRDPL.2278-0238.2018.7(4).3030-3033, 10.21276/ IJRDPL.2278-0238.2018.7(4).3030-3033, DOI 10.21276/IJRDPL.2278-0238.2018.7(4).3030-3033]
   Costa PZ, 2013, LIFE SCI, V92, P1037, DOI 10.1016/j.lfs.2013.04.001
   Davis SC, 2017, INT WOUND J, V14, P937, DOI 10.1111/iwj.12734
   Deng J, 2023, J ORTHOP SURG RES, V18, DOI 10.1186/s13018-023-03854-x
   Dinh T., 2011, Diabetes Management, V1, P509, DOI DOI 10.2217/DMT.11.44
   Dunnill C, 2017, INT WOUND J, V14, P89, DOI 10.1111/iwj.12557
   Frykberg RG, 2021, MEDICINA-LITHUANIA, V57, DOI 10.3390/medicina57090917
   Galicia-Garcia U, 2020, INT J MOL SCI, V21, DOI 10.3390/ijms21176275
   Gras C, 2015, MOL MED, V21, P296, DOI 10.2119/molmed.2014.00172
   Greenhalgh DG, 2003, CLIN PLAST SURG, V30, P37, DOI 10.1016/S0094-1298(02)00066-4
   Hu H, 2015, DIABETES-METAB RES, V31, P127, DOI 10.1002/dmrr.2560
   Kroeze KL, 2012, WOUND REPAIR REGEN, V20, P294, DOI 10.1111/j.1524-475X.2012.00789.x
   Lacci Kathleen M., 2010, Yale Journal of Biology and Medicine, V83, P1
   Lauer G, 2000, J INVEST DERMATOL, V115, P12, DOI 10.1046/j.1523-1747.2000.00036.x
   Lee B, 2005, J MOL BIOL, V345, P1083, DOI 10.1016/j.jmb.2004.11.027
   Lima MHM, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0036974
   Lipsky BA, 2010, DIABETES CARE, V33, P1143, DOI 10.2337/dc10-0393
   Liu Y, 2018, BIOL OPEN, V7, DOI 10.1242/bio.026187
   Liu Y, 2021, FRONT ENDOCRINOL, V12, DOI 10.3389/fendo.2021.744868
   Lázaro-Martínez JL, 2020, J CLIN MED, V9, DOI 10.3390/jcm9124032
   Lyttle BD, 2023, FRONT MED-LAUSANNE, V10, DOI 10.3389/fmed.2023.1140979
   Mady FM, 2016, DRUG DES DEV THER, V10, P1101, DOI 10.2147/DDDT.S103423
   Maione AG, 2016, WOUND REPAIR REGEN, V24, P630, DOI 10.1111/wrr.12437
   Mouës CM, 2007, J PLAST RECONSTR AES, V60, P672, DOI 10.1016/j.bjps.2006.01.041
   Muller M, 2008, DIABETIC MED, V25, P419, DOI 10.1111/j.1464-5491.2008.02414.x
   Ozdemir D, 2019, TRENDS CARDIOVAS MED, V29, P131, DOI 10.1016/j.tcm.2018.08.002
   Pirilä E, 2007, WOUND REPAIR REGEN, V15, P47, DOI 10.1111/j.1524-475X.2006.00184.x
   Sargen MR, 2013, J DIABETES COMPLICAT, V27, P128, DOI 10.1016/j.jdiacomp.2012.09.003
   Singer AJ, 1999, NEW ENGL J MED, V341, P738, DOI 10.1056/NEJM199909023411006
   Spampinato SF, 2020, PHARMACEUTICALS-BASE, V13, DOI 10.3390/ph13040060
   Stojadinovic O, 2013, IMMUNOL RES, V57, P222, DOI 10.1007/s12026-013-8474-z
   Tan SY, 2019, DIAB MET SYND CLIN R, V13, P364, DOI 10.1016/j.dsx.2018.10.008
   Vassallo IM, 2015, WOUNDS, V27, P180
   Wong Andrew Yew Wei, 2022, Cureus, V14, pe27180, DOI [10.7759/cureus.27180, 10.7759/cureus.27180]
NR 41
TC 9
Z9 9
U1 8
U2 66
PU BENTHAM SCIENCE PUBL LTD
PI SHARJAH
PA EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB
   EMIRATES
SN 1389-2037
EI 1875-5550
J9 CURR PROTEIN PEPT SC
JI Curr. Protein Pept. Sci.
PY 2024
VL 25
IS 3
BP 200
EP 205
DI 10.2174/0113892037276171231016103320
PG 6
WC Biochemistry & Molecular Biology
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Biochemistry & Molecular Biology
GA JR1J7
UT WOS:001174798400003
PM 37909438
DA 2026-07-24
ER

PT J
AU Sartelli, M
   Guirao, X
   Hardcastle, TC
   Kluger, Y
   Boermeester, MA
   Rasa, K
   Ansaloni, L
   Coccolini, F
   Montravers, P
   Abu-Zidan, FM
   Bartoletti, M
   Bassetti, M
   Ben-Ishay, O
   Biffl, WL
   Chiara, O
   Chiarugi, M
   Coimbra, R
   De Rosa, FG
   De Simone, B
   Di Saverio, S
   Giannella, M
   Gkiokas, G
   Khokha, V
   Labricciosa, FM
   Leppäniemi, A
   Litvin, A
   Moore, EE
   Negoi, I
   Pagani, L
   Peghin, M
   Picetti, E
   Pintar, T
   Pupelis, G
   Rubio-Perez, I
   Sakakushev, B
   Segovia-Lohse, H
   Sganga, G
   Shelat, V
   Sugrue, M
   Tarasconi, A
   Tranà, C
   Ulrych, J
   Viale, P
   Catena, F
AF Sartelli, Massimo
   Guirao, Xavier
   Hardcastle, Timothy C.
   Kluger, Yoram
   Boermeester, Marja. A.
   Rasa, Kemal
   Ansaloni, Luca
   Coccolini, Federico
   Montravers, Philippe
   Abu-Zidan, Fikri M.
   Bartoletti, Michele
   Bassetti, Matteo
   Ben-Ishay, Offir
   Biffl, Walter L.
   Chiara, Osvaldo
   Chiarugi, Massimo
   Coimbra, Raul
   De Rosa, Francesco Giuseppe
   De Simone, Belinda
   Di Saverio, Salomone
   Giannella, Maddalena
   Gkiokas, George
   Khokha, Vladimir
   Labricciosa, Francesco M.
   Leppaniemi, Ari
   Litvin, Andrey
   Moore, Ernest E.
   Negoi, Ionut
   Pagani, Leonardo
   Peghin, Maddalena
   Picetti, Edoardo
   Pintar, Tadeja
   Pupelis, Guntars
   Rubio-Perez, Ines
   Sakakushev, Boris
   Segovia-Lohse, Helmut
   Sganga, Gabriele
   Shelat, Vishal
   Sugrue, Michael
   Tarasconi, Antonio
   Trana, Cristian
   Ulrych, Jan
   Viale, Pierluigi
   Catena, Fausto
TI 2018 WSES/SIS-E consensus conference: recommendations for the management
   of skin and soft-tissue infections
SO WORLD JOURNAL OF EMERGENCY SURGERY
LA English
DT Review
DE Soft-tissue infections; Necrotizing infection; Surgical site infection
ID RESISTANT STAPHYLOCOCCUS-AUREUS; VACUUM-ASSISTED CLOSURE; LABORATORY
   RISK INDICATOR; EVALUATING CEFTAROLINE FOSAMIL; INJECTING DRUG-USERS;
   TOXIC-SHOCK-SYNDROME; NECROTIZING FASCIITIS; FOURNIERS GANGRENE;
   COMPLICATED SKIN; DOUBLE-BLIND
AB Skin and soft-tissue infections (SSTIs) encompass a variety of pathological conditions that involve the skin and underlying subcutaneous tissue, fascia, or muscle, ranging from simple superficial infections to severe necrotizing infections. SSTIs are a frequent clinical problem in surgical departments. In order to clarify key issues in the management of SSTIs, a task force of experts met in Bertinoro, Italy, on June 28, 2018, for a specialist multidisciplinary consensus conference under the auspices of the World Society of Emergency Surgery (WSES) and the Surgical Infection Society Europe (SIS-E). The multifaceted nature of these infections has led to a collaboration among general and emergency surgeons, intensivists, and infectious disease specialists, who have shared these clinical practice recommendations.
C1 [Sartelli, Massimo; Trana, Cristian] Macerata Hosp, Dept Surg, Macerata, Italy.
   [Guirao, Xavier] Parc Tauli Hosp Univ, Dept Gen Surg, Unit Endocrine Head & Neck Surg, Sabadell, Spain.
   [Guirao, Xavier] Parc Tauli Hosp Univ, Dept Gen Surg, Unit Surg Infect Support, Sabadell, Spain.
   [Hardcastle, Timothy C.] Inkosi Albert Luthuli Cent Hosp, Trauma Serv, Durban, South Africa.
   [Hardcastle, Timothy C.] Nelson R Mandela Sch Clin Med, Dept Surg, Durban, South Africa.
   [Kluger, Yoram; Ben-Ishay, Offir] Rambam Hlth Care Campus, Dept Gen Surg, Div Surg, Haifa, Israel.
   [Boermeester, Marja. A.] Acad Med Ctr, Dept Surg, Amsterdam, Netherlands.
   [Rasa, Kemal] Anadolu Med Ctr, Dept Surg, Kocaali, Turkey.
   [Ansaloni, Luca; Coccolini, Federico] Bufalini Hosp, Dept Gen Surg, Cesena, Italy.
   [Montravers, Philippe] Paris Diderot Sorbonne Cite Univ, Anesthesiol & Crit Care Med, Bichat Claude Bernard Univ Hosp, Paris, France.
   [Abu-Zidan, Fikri M.] UAE Univ, Dept Surg, Coll Med & Hlth Sci, Al Ain, U Arab Emirates.
   [Bartoletti, Michele; Giannella, Maddalena; Viale, Pierluigi] Alma Mater Studiorum Univ Bologna, Infect Dis Unit, Dept Med & Surg Sci, Bologna, Italy.
   [Bassetti, Matteo; Peghin, Maddalena] Univ Udine, Dept Med, Infect Dis Div, Udine, Italy.
   [Bassetti, Matteo; Peghin, Maddalena] Azienda Sanit Univ Intergrata Udine, Udine, Italy.
   [Biffl, Walter L.] Scripps Mem Hosp La Jolla, Trauma & Acute Care Surg, La Jolla, CA USA.
   [Chiara, Osvaldo] State Univ Milano, Niguarda Hosp Milano, Gen Surg Trauma Team, Milan, Italy.
   [Chiarugi, Massimo] State Univ Pisa, Cisanello Hosp, Surg Unit, Pisa, Italy.
   [Coimbra, Raul] Riverside Univ Hlth Syst Med Ctr, Moreno Valley, CA USA.
   [Coimbra, Raul] Loma Linda Univ, Sch Med, Moreno Valley, CA USA.
   [De Rosa, Francesco Giuseppe] Univ Turin, Dept Med Sci, Infect Dis, Turin, Italy.
   [De Simone, Belinda] Reg Hosp Perpignan, Unit Gen Emergency & Trauma Surg, Perpignan, France.
   [Di Saverio, Salomone] Cambridge Univ Hosp NHS Fdn Trust, Dept Surg, Addenbrookes Hosp, Cambridge, England.
   [Gkiokas, George] Natl & Kapodistrian Univ Athens, Dept Surg 2, Aretaie Univ Hosp, Athens, Greece.
   [Khokha, Vladimir] City Hosp, Dept Emergency Surg, Mozyr, BELARUS.
   [Labricciosa, Francesco M.] Global Alliance Infect Surg, Porto, Portugal.
   [Leppaniemi, Ari] Univ Hosp Meilahti, Abdominal Ctr, Helsinki, Finland.
   [Litvin, Andrey] Immanuel Kant Balt Fed Univ, Dept Surg Disciplines, Reg Clin Hosp, Kaliningrad, Russia.
   [Moore, Ernest E.] Univ Colorado, Dept Surg, Denver Hlth Med Ctr, Denver, CO 80202 USA.
   [Negoi, Ionut] Emergency Hosp Bucharest, Dept Surg, Bucharest, Romania.
   [Pagani, Leonardo] Bolzano Cent Hosp, Infect Dis Unit, Bolzano, Italy.
   [Picetti, Edoardo] Azienda Osped Univ Parma, Dept Anesthesia & Intens Care, Parma, Italy.
   [Pintar, Tadeja] UMC Ljubljana, Dept Surg, Ljubljana, Slovenia.
   [Pupelis, Guntars] Riga East Univ Hosp Gailezers, Dept Gen & Emergency Surg, Riga, Latvia.
   [Rubio-Perez, Ines] La Paz Univ Hosp, Gen Surg Dept, Colorectal Surg Unit, Madrid, Spain.
   [Sakakushev, Boris] Med Univ, Univ Hosp St George, Gen Surg Dept, Plovdiv, Bulgaria.
   [Segovia-Lohse, Helmut] Univ Nacl Asuncion, Dept Surg 2, Hosp Clin, San Lorenzo, Paraguay.
   [Sganga, Gabriele; Catena, Fausto] Univ Cattolica Sacro Cuore, Div Emergency Surg, Fdn Policlin Univ A Gemelli IRCCS, Rome, Italy.
   [Shelat, Vishal] Tan Tock Seng Hosp, Gen Surg, Singapore, Singapore.
   [Sugrue, Michael] Letterkenny Univ Hosp, Dept Surg, Letterkenny, Ireland.
   [Sugrue, Michael] Donegal Clin Res Acad, Letterkenny, Ireland.
   [Tarasconi, Antonio] Parma Maggiore Hosp, Dept Emergency Surg, Parma, Italy.
   [Ulrych, Jan] Charles Univ Prague, Dept Surg 1, Fac Med 1, Dept Abdominal Thorac Surg & Traumatol, Prague, Czech Republic.
   [Ulrych, Jan] Gen Univ Hosp, Prague, Czech Republic.
C3 Autonomous University of Barcelona; Parc Tauli Hospital Universitari;
   Autonomous University of Barcelona; Parc Tauli Hospital Universitari;
   Technion Israel Institute of Technology; Rambam Health Care Campus;
   University of Amsterdam; Academic Medical Center Amsterdam; Anadolu
   Medical Center; Assistance Publique Hopitaux Paris (APHP); Universite
   Paris Cite; Hopital Universitaire Bichat-Claude Bernard - APHP; United
   Arab Emirates University; University of Bologna; University of Udine;
   University of Milan; Loma Linda University; University of Turin;
   Cambridge University Hospitals NHS Foundation Trust; Addenbrooke's
   Hospital; University of Cambridge; National & Kapodistrian University of
   Athens; Immanuel Kant Baltic Federal University; University of Colorado
   System; University of Colorado Denver; Denver Health Medical Center;
   Krankenhaus Bozen; University of Parma; University Hospital of Parma;
   University Medical Centre Ljubljana; Riga East University Hospital;
   Hospital Universitario La Paz; Medical University Plovdiv; Universidad
   Nacional de Asuncion; Catholic University of the Sacred Heart; IRCCS
   Policlinico Gemelli; Tan Tock Seng Hospital; University of Parma;
   University Hospital of Parma; Charles University Prague; General
   University Hospital Prague
RP Sartelli, M (通讯作者)，Macerata Hosp, Dept Surg, Macerata, Italy.
EM massimosartelli@gmail.com
RI Chiarugi, Massimo/ABQ-7280-2022; Ulrych, Jan/I-9617-2017; Pagani,
   Leonardo/AFR-8064-2022; Pintar, Tadeja/HNS-7436-2023; Gkiokas,
   Georgios/AAE-6312-2020; /AAD-7440-2020; Abu-Zidan, Fikri/GWE-2835-2022;
   Coccolini, Federico/AAJ-6507-2020; De Simone, Belinda/AAD-5646-2019;
   Shelat, Vishal/ABC-3293-2021; Bassetti, Matteo/L-3081-2019; Khokha,
   Vladimir/IVU-7489-2023; Leppäniemi, Ari/GQZ-7991-2022; Ansaloni,
   Luca/AAJ-6507-2020; Segovia Lohse, Helmut Alfredo/K-2392-2017; Negoi,
   Ionut/A-9039-2012; Di Saverio, Salomone/G-1437-2012; Sakakushev,
   Boris/MGV-4913-2025; DE ROSA, Francesco Giuseppe/AAC-7275-2022; Coimbra,
   Raul/AAP-3019-2020; chiara, osvaldo/R-6151-2018; Tarasconi,
   Antonio/H-4574-2018; Hardcastle, Timothy/N-5830-2013; Litvin,
   Andrey/B-2254-2017; Rasa, Huseyin Kemal/AAG-3531-2021; GUIRAO,
   XAVIER/AGV-5502-2022; Ansaloni, Luca/AAP-9134-2020; Giannella,
   Maddalena/K-9090-2016; Bartoletti, Michele/K-4621-2018
OI Chiarugi, Massimo/0000-0001-6905-2499; Ulrych, Jan/0000-0002-5225-9562;
   Coccolini, Federico/0000-0001-6364-4186; Shelat,
   Vishal/0000-0003-3988-8142; Bassetti, Matteo/0000-0002-0145-9740;
   Ansaloni, Luca/0000-0001-6427-0307; Segovia Lohse, Helmut
   Alfredo/0000-0003-3255-5345; Negoi, Ionut/0000-0002-6950-9599;
   Boermeester, Marja/0000-0003-3890-8105; Di Saverio,
   Salomone/0000-0001-5685-5022; Sakakushev, Boris/0000-0001-8399-0115; DE
   ROSA, Francesco Giuseppe/0000-0001-8338-0130; Coimbra,
   Raul/0000-0002-3759-6851; chiara, osvaldo/0000-0003-2409-2109; Peghin,
   Maddalena/0000-0002-4640-679X; Tarasconi, Antonio/0000-0001-6588-2268;
   Hardcastle, Timothy/0000-0002-3967-0234; Litvin,
   Andrey/0000-0002-9330-6513; Rasa, Huseyin Kemal/0000-0002-2872-3249;
   GUIRAO, XAVIER/0000-0001-9201-7851; Ansaloni, Luca/0000-0001-6427-0307;
   Giannella, Maddalena/0000-0001-8273-7601; Rubio-Perez,
   Ines/0000-0002-3960-6865; Bartoletti, Michele/0000-0002-1099-3283
CR Abcarian Herand, 2011, Clin Colon Rectal Surg, V24, P14, DOI 10.1055/s-0031-1272819
   Abrahamian FM, 2011, CLIN MICROBIOL REV, V24, P231, DOI 10.1128/CMR.00041-10
   Agarwal R, 2018, CLIN MICROBIOL INFEC, V24, P361, DOI 10.1016/j.cmi.2017.08.028
   Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe276, DOI [10.1016/s1473-3099(16)30402-9, 10.1016/s1473-3099(16)30398-x, 10.1016/S1473-3099(16)30398-X]
   Allegranzi Benedetta, 2016, Lancet Infect Dis, V16, pe288, DOI 10.1016/S1473-3099(16)30402-9
   Anaya DA, 2007, CLIN INFECT DIS, V44, P705, DOI 10.1086/511638
   Andreasen TJ, 2001, PLAST RECONSTR SURG, V107, P1025, DOI 10.1097/00006534-200104010-00019
   Angoules AG, 2007, INJURY, V38, pS19, DOI 10.1016/j.injury.2007.10.030
   Angus DC, 2013, NEW ENGL J MED, V369, P840, DOI 10.1056/NEJMra1208623
   [Anonymous], 2015, HEALTH TECHNOL ASSES, V19, P1, DOI 10.3310/hta19430
   [Anonymous], 2014, CURR PROB SURG, V51, P344, DOI 10.1067/j.cpsurg.2014.06.001
   [Anonymous], GUID IND AC BACT SKI
   [Anonymous], ANN SURG
   [Anonymous], 2016, CLIN INFECT DIS, DOI DOI 10.1093/cid/civ1199
   Arad G, 2011, PLOS BIOL, V9, DOI 10.1371/journal.pbio.1001149
   Atema JJ, 2017, WORLD J SURG, V41, P1993, DOI 10.1007/s00268-017-3962-2
   Atema JJ, 2016, AM J SURG, V212, P982, DOI 10.1016/j.amjsurg.2016.05.003
   Awad SS, 2007, AM J SURG, V194, P606, DOI 10.1016/j.amjsurg.2007.07.016
   Bangert S, 2012, PEDIATR DERMATOL, V29, P243, DOI 10.1111/j.1525-1470.2011.01700.x
   Bassetti Matteo, 2018, Curr Opin Infect Dis, V31, P163, DOI 10.1097/QCO.0000000000000434
   Bassetti M, 2018, CURR OPIN INFECT DIS, V31, P141, DOI 10.1097/QCO.0000000000000430
   Bechar J, 2017, ANN ROY COLL SURG, V99, P341, DOI 10.1308/rcsann.2017.0053
   Bernarda P, 2008, ANN DERMATOL VENER, V135, P13, DOI 10.1016/j.annder.2007.06.004
   Berríos SI, 2017, JAMA SURG, V152, P784, DOI 10.1001/jamasurg.2017.0904
   Bilton BD, 1998, AM SURGEON, V64, P397
   Binswanger IA, 2000, CLIN INFECT DIS, V30, P579, DOI 10.1086/313703
   Bliziotis IA, 2010, ANN PHARMACOTHER, V44, P97, DOI 10.1345/aph.1M264
   Boyer A, 2009, INTENS CARE MED, V35, P847, DOI 10.1007/s00134-008-1373-4
   Bozkurt O, 2015, INT UROL NEPHROL, V47, P243, DOI 10.1007/s11255-014-0897-5
   Brett MM, 2005, EPIDEMIOL INFECT, V133, P575, DOI 10.1017/S0950268805003845
   Bronder C S, 2004, Colorectal Dis, V6, P518, DOI 10.1111/j.1463-1318.2004.00663.x
   Bueno-Lledó J, 2017, AM J SURG, V213, P50, DOI 10.1016/j.amjsurg.2016.03.007
   Bulger EM, 2014, JAMA SURG, V149, P528, DOI 10.1001/jamasurg.2013.4841
   Carapetis JR, 2014, CLIN INFECT DIS, V59, P358, DOI 10.1093/cid/ciu304
   Carratalà J, 2003, EUR J CLIN MICROBIOL, V22, P151, DOI 10.1007/s10096-003-0902-x
   Cenizal MJ, 2007, ANTIMICROB AGENTS CH, V51, P2628, DOI 10.1128/AAC.00206-07
   Cevasco M, 2012, SURG INFECT, V13, P209, DOI 10.1089/sur.2012.123
   Chahine Elias B, 2015, Consult Pharm, V30, P386, DOI [10.4140/tcp.n.2015.386, 10.4140/TCP.n.2015.386]
   Chao WN, 2013, AM J SURG, V206, P32, DOI 10.1016/j.amjsurg.2012.08.008
   Cheadle William G, 2006, Surg Infect (Larchmt), V7 Suppl 1, pS7, DOI 10.1089/sur.2006.7.s-7
   Citak M, 2011, SPINE, V36, pE1225, DOI 10.1097/BRS.0b013e3182059950
   Cobb WS, 2009, AM SURGEON, V75, P762
   Colak E, 2014, TURK J EMERG MED, V14, P15, DOI 10.5505/1304.7361.2014.55476
   Corbin V, 2010, ANN DERMATOL VENER, V137, P5, DOI 10.1016/j.annder.2009.12.002
   Corey GR, 2010, J ANTIMICROB CHEMOTH, V65, piv41, DOI 10.1093/jac/dkq254
   Corey GR, 2010, CLIN INFECT DIS, V51, P641, DOI 10.1086/655827
   Corman JM, 1999, BJU INT, V84, P85
   Costerton JW, 2005, INT J ARTIF ORGANS, V28, P1062, DOI 10.1177/039139880502801103
   Coyle EA, 2003, ANTIMICROB AGENTS CH, V47, P1752, DOI 10.1128/AAC.47.5.1752-1755.2003
   Darenberg J, 2003, CLIN INFECT DIS, V37, P333, DOI 10.1086/376630
   de Geus HRH, 2005, INTENS CARE MED, V31, P601, DOI 10.1007/s00134-004-2553-5
   DELLINGER RP, 2013, CRIT CARE MED, V41, P580, DOI DOI 10.1097/CCM.0B013E31827E83AF
   El-Menyar A, 2017, SCAND J TRAUMA RESUS, V25, DOI 10.1186/s13049-017-0359-z
   Emohare O, 2004, J BURN CARE REHABIL, V25, P161, DOI 10.1097/01.BCR.0000111764.67904.CD
   Eriksson B, 1996, CLIN INFECT DIS, V23, P1091, DOI 10.1093/clinids/23.5.1091
   Eron Lawrence J., 2003, Journal of Antimicrobial Chemotherapy, V52, pi3
   Eskes A, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008059.pub3
   Esposito S, 2013, EUR J CLIN MICROBIOL, V32, P971, DOI 10.1007/s10096-013-1840-x
   Esposito S, 2011, J CHEMOTHERAPY, V23, P251, DOI 10.1179/joc.2011.23.5.251
   Estrada O, 2009, TECH COLOPROCTOL, V13, P157, DOI 10.1007/s10151-009-0474-6
   Evgeniou E, 2013, Eplasty, V13, pe27
   Falagas ME, 2008, LANCET INFECT DIS, V8, P53, DOI 10.1016/S1473-3099(07)70312-2
   Fitzmaurice M, 2006, J PLAST RECONSTR AES, V59, P1249, DOI 10.1016/j.bjps.2006.02.009
   Friederichs J, 2013, AM J SURG, V206, P368, DOI 10.1016/j.amjsurg.2012.11.024
   Garau J, 2013, CLIN MICROBIOL INFEC, V19, pE377, DOI 10.1111/1469-0691.12235
   Gelbard RB, 2018, J TRAUMA ACUTE CARE, V85, P208, DOI 10.1097/TA.0000000000001857
   Ghnnam WM, 2008, J POSTGRAD MED, V54, P106, DOI 10.4103/0022-3859.40776
   Gilchrist J, 2008, INJURY PREV, V14, P296, DOI 10.1136/ip.2007.016220
   GOLDSTEIN EJC, 1992, CLIN INFECT DIS, V14, P633, DOI 10.1093/clinids/14.3.633
   Guyatt G, 2006, CHEST, V129, P174, DOI 10.1378/chest.129.1.174
   Hofmann P, 2006, ZBL CHIR, V131, pS72, DOI 10.1055/s-2006-921475
   HORAN TC, 1992, INFECT CONT HOSP EP, V13, P606
   Howell GM, 2011, SURG INFECT, V12, P185, DOI 10.1089/sur.2011.032
   Hua C, 2018, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011680.pub2
   Huang WS, 2006, ASIAN J SURG, V29, P133
   Itani KMF, 2010, AM J SURG, V199, P804, DOI 10.1016/j.amjsurg.2009.08.045
   Jaindl M, 2012, INJURY, V43, P2117, DOI 10.1016/j.injury.2012.04.016
   Kadri SS, 2017, CLIN INFECT DIS, V64, P877, DOI 10.1093/cid/ciw871
   Kathju S, 2015, SURG INFECT, V16, P45, DOI 10.1089/sur.2014.026
   Khalil PN, 2008, EUR J MED RES, V13, P415
   Kim KT, 2011, RADIOLOGY, V259, P816, DOI 10.1148/radiol.11101164
   Kobayashi L, 2011, J TRAUMA, V71, P1400, DOI 10.1097/TA.0b013e31820db8fd
   Latifi R, 2016, WORLD J SURG, V40, P836, DOI 10.1007/s00268-015-3294-z
   Linnér A, 2014, CLIN INFECT DIS, V59, P851, DOI 10.1093/cid/ciu449
   LLERA JL, 1985, ANN EMERG MED, V14, P15, DOI 10.1016/S0196-0644(85)80727-7
   Lloyd-Smith Elisa, 2005, Harm Reduct J, V2, P24, DOI 10.1186/1477-7517-2-24
   Lonergan S, 2004, J EMERG MED, V26, P47, DOI 10.1016/j.jemermed.2003.06.003
   MACFIE J, 1977, BRIT J SURG, V64, P264, DOI 10.1002/bjs.1800640410
   Macmorran E, 2017, EPIDEMIOL INFECT, V145, P2817, DOI [10.1017/S0950268817001716, 10.1017/s0950268817001716]
   Majeski J, 1997, SOUTHERN MED J, V90, P1065, DOI 10.1097/00007611-199711000-00001
   Malachowa N, 2010, CELL MOL LIFE SCI, V67, P3057, DOI 10.1007/s00018-010-0389-4
   Malghem J, 2013, JOINT BONE SPINE, V80, P146, DOI 10.1016/j.jbspin.2012.08.009
   Mallikarjuna M N, 2012, ISRN Surg, V2012, P942437, DOI 10.5402/2012/942437
   Marwick C, 2011, J ANTIMICROB CHEMOTH, V66, P387, DOI 10.1093/jac/dkq362
   Mavros MN, 2011, WORLD J SURG, V35, P2389, DOI 10.1007/s00268-011-1266-5
   May AK, 2009, SURG INFECT, V10, P467, DOI 10.1089/sur.2009.012
   May AK, 2009, SURG CLIN N AM, V89, P403, DOI 10.1016/j.suc.2008.09.006
   McCloud JM, 2007, ANN ROY COLL SURG, V89, P301, DOI 10.1308/003588407X179134
   McCool R, 2017, BMC INFECT DIS, V17, DOI 10.1186/s12879-016-2100-3
   Medeiros I, 2001, COCHRANE DB SYST REV, V2
   Merlino James I, 2007, Cleve Clin J Med, V74 Suppl 4, pS21
   Moet GJ, 2007, DIAGN MICR INFEC DIS, V57, P7, DOI 10.1016/j.diagmicrobio.2006.05.009
   Moise-Broder PA, 2004, CLIN INFECT DIS, V38, P1700, DOI 10.1086/421092
   Mongelluzzo J, 2017, WEST J EMERG MED, V18, P398, DOI 10.5811/westjem.2016.12.32838
   Montgomery A, 2016, FRONT SURG, V2, DOI 10.3389/fsurg.2015.00067
   Morris AD, 2008, BMJ CLIN EVID, V2008, P1708
   Morua Alejandro Garcia, 2009, Arch Esp Urol, V62, P532
   Napolitano LM, 2009, INFECT DIS CLIN N AM, V23, P571, DOI 10.1016/j.idc.2009.04.006
   Nathwani D, 2008, J ANTIMICROB CHEMOTH, V61, P976, DOI 10.1093/jac/dkn096
   Nicks BA, 2010, INT J EMERG MED, V3, P399, DOI 10.1007/s12245-010-0217-5
   Nouraei S A R, 2003, J Wound Care, V12, P147
   Oczenski W, 2004, J CARDIOTHOR VASC AN, V18, P336, DOI 10.1053/j.jvca.2004.03.016
   Oehler RL, 2009, LANCET INFECT DIS, V9, P439, DOI 10.1016/S1473-3099(09)70110-0
   Oetting P, 2006, CHIRURG, V77, P586, DOI 10.1007/s00104-006-1200-9
   Okoye O, 2013, AM SURGEON, V79, P1081
   Orgill DP, 2009, SURGERY, V146, P40, DOI 10.1016/j.surg.2009.02.002
   Ovington Liza, 2003, Ostomy Wound Manage, V49, P8
   Owens P, 2015, Ir Med J, V108, P78
   Paton B Lauren, 2007, Surg Infect (Larchmt), V8, P337
   Peinemann F, 2011, DTSCH ARZTEBL INT, V108, P381, DOI 10.3238/arztebl.2011.0381
   Pérez-Köhler B, 2016, SURG INFECT, V17, P124, DOI 10.1089/sur.2015.078
   Pollini RA, 2010, INT J INFECT DIS, V14, pE117, DOI 10.1016/j.ijid.2010.02.2238
   Roberts JA, 2014, LANCET INFECT DIS, V14, P498, DOI 10.1016/S1473-3099(14)70036-2
   Romani L, 2015, PLOS NEGLECT TROP D, V9, DOI 10.1371/journal.pntd.0003452
   Rosen MJ, 2013, ANN SURG, V257, P991, DOI 10.1097/SLA.0b013e3182849871
   Rossolini Gian Maria, 2009, Infez Med, V17 Suppl 4, P18
   Rozeboom A L, 2006, J Wound Care, V15, P117
   Sabbaj A, 2009, ACAD EMERG MED, V16, P1290, DOI 10.1111/j.1553-2712.2009.00536.x
   Sartelli M, 2014, WORLD J EMERG SURG, V9, DOI 10.1186/1749-7922-9-57
   Seaton RA, 2008, J ANTIMICROB CHEMOTH, V62, P15, DOI 10.1093/jac/dkn368
   Sganga G, 2016, WORLD J EMERG SURG, V11, DOI 10.1186/s13017-016-0086-1
   Shah SS, 2009, CLIN INFECT DIS, V49, P1369, DOI 10.1086/606048
   Shubinets V, 2018, ANN PLAS SURG, V80, P145, DOI 10.1097/SAP.0000000000001189
   Singer M, 2016, JAMA-J AM MED ASSOC, V315, P801, DOI 10.1001/jama.2016.0287
   Smeets L, 2007, ACTA CHIR BELG, V107, P29, DOI 10.1080/00015458.2007.11680007
   Soh CR, 2012, INTENS CARE MED, V38, P1143, DOI 10.1007/s00134-012-2558-4
   Spijkerman IJB, 1996, J CLIN EPIDEMIOL, V49, P1149, DOI 10.1016/0895-4356(96)00180-1
   STAMENKOVIC I, 1984, NEW ENGL J MED, V310, P1689, DOI 10.1056/NEJM198406283102601
   Stevens DL, 2007, J INFECT DIS, V195, P202, DOI 10.1086/510396
   Stevens DL, 2017, NEW ENGL J MED, V377, P2253, DOI 10.1056/NEJMra1600673
   Stevens DL, 2014, CLIN INFECT DIS, V59, P147, DOI [10.1093/cid/ciu444, 10.1093/cid/ciu296]
   Swain RA, 2013, ANN ROY COLL SURG, V95, P57, DOI 10.1308/003588413X13511609956093
   Szumowski JD, 2007, ANTIMICROB AGENTS CH, V51, P423, DOI 10.1128/AAC.01244-06
   Tong SYC, 2015, EPIDEMIOL INFECT, V143, P1519, DOI 10.1017/S0950268814002611
   Tuncel A, 2006, EUR UROL, V50, P838, DOI 10.1016/j.eururo.2006.01.030
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   Ubbink DT, 2008, COCHRANE DB SYST REV, V3
   Ustin JS, 2011, CRIT CARE MED, V39, P2156, DOI 10.1097/CCM.0b013e31821cb246
   Vandenesch F, 2003, EMERG INFECT DIS, V9, P978
   Walshaw CF, 1996, CLIN RADIOL, V51, P429, DOI 10.1016/S0009-9260(96)80164-4
   Weber D J, 1991, Infect Dis Clin North Am, V5, P663
   Wilcox MH, 2010, J ANTIMICROB CHEMOTH, V65, piv53, DOI 10.1093/jac/dkq255
   Wong CH, 2004, CRIT CARE MED, V32, P1535, DOI 10.1097/01.CCM.0000129486.35458.7D
   Wong CH, 2003, J BONE JOINT SURG AM, V85A, P1454, DOI 10.2106/00004623-200308000-00005
   Yanar H, 2006, WORLD J SURG, V30, P1750, DOI 10.1007/s00268-005-0777-3
   Yen ZS, 2002, ACAD EMERG MED, V9, P1448, DOI 10.1111/j.1553-2712.2002.tb01619.x
   Yeniyol CO, 2004, UROLOGY, V64, P218, DOI 10.1016/j.urology.2004.03.049
   Yue JR, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008056.pub2
   Zacharias N, 2010, ARCH SURG-CHICAGO, V145, P452, DOI 10.1001/archsurg.2010.50
   [No title captured]
   [No title captured]
NR 161
TC 189
Z9 237
U1 2
U2 21
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1749-7922
J9 WORLD J EMERG SURG
JI World J. Emerg. Surg.
PD DEC 14
PY 2018
VL 13
AR 58
DI 10.1186/s13017-018-0219-9
PG 24
WC Emergency Medicine; Surgery
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Emergency Medicine; Surgery
GA HE4ZC
UT WOS:000453377700001
PM 30564282
OA Green Submitted, gold
DA 2026-07-24
ER

PT J
AU Kanuck, DM
   Zgonis, T
   Jolly, GP
AF Kanuck, DM
   Zgonis, T
   Jolly, GP
TI Necrotizing fasciitis in a patient with type 2 diabetes mellitus
SO JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION
LA English
DT Article
ID VACUUM-ASSISTED CLOSURE; SOFT-TISSUE INFECTIONS; HYPERBARIC-OXYGEN
   THERAPY; GROUP-A STREPTOCOCCUS; CLOSTRIDIUM-PERFRINGENS; EARLY
   RECOGNITION; WOUND CONTROL; GAS-GANGRENE; PATHOGENESIS; MANAGEMENT
AB Necrotizing fasciitis is a soft-tissue infection characterized by extensive necrosis of subcutaneous fat, neurovascular structures, and fascia. In general, fascial necrosis precedes muscle and skin involvement, hence its namesake. Initially, this uncommon and rapidly progressive disease process can present as a form of cellulitis or superficial abscess. However, the high morbidity and mortality rates associated with necrotizing fasciitis suggest a more serious, ominous condition. A delay in diagnosis can result in progressive advancement highlighted by widespread infection, multiple-organ involvement, and, ultimately, death. We present a case of limb salvage in a 52-year-old patient with type 2 diabetes mellitus and progressive fascial necrosis. A detailed review of the literature is presented, and current treatment modalities are described. Aggressive surgical debridement, comprehensive medical management of the sepsis and comorbidities, and timely closure of the resultant wound or wounds are essential for a successful outcome.
C1 Univ Texas, Hlth Sci Ctr, Dept Orthopaed, San Antonio, TX 78229 USA.
   Ctr Reconstruct Foot Surg PC, Plainville, CT USA.
C3 University of Texas System; University of Texas at San Antonio
RP Zgonis, T (通讯作者)，Univ Texas, Hlth Sci Ctr, Dept Orthopaed, 7703 Floyd Curl Dr,MCS 7776, San Antonio, TX 78229 USA.
CR Argenta LC, 1997, ANN PLAS SURG, V38, P563, DOI 10.1097/00000637-199706000-00002
   Armstrong D G, 1996, J Foot Ankle Surg, V35, P280
   Armstrong DG, 1996, J AM PODIAT MED ASSN, V86, P224, DOI 10.7547/87507315-86-5-224
   Aronoff DM, 2003, MEDICINE, V82, P225, DOI 10.1097/00005792-200307000-00001
   Awad MM, 2001, INFECT IMMUN, V69, P7904, DOI 10.1128/IAI.69.12.7904-7910.2001
   Becker M, 1997, RADIOLOGY, V202, P471, DOI 10.1148/radiology.202.2.9015076
   BROOK I, 1995, J CLIN MICROBIOL, V33, P2382, DOI 10.1128/JCM.33.9.2382-2387.1995
   Bryant AE, 2003, CLIN MICROBIOL REV, V16, P451, DOI 10.1128/CMR.16.3.451-462.2003
   *CDCP, 2001, ACT BACT COR SURV AB
   Cha J Y, 1994, J Foot Ankle Surg, V33, P148
   Chao HC, 1999, J ULTRAS MED, V18, P277
   Chapnick EK, 1996, INFECT DIS CLIN N AM, V10, P835, DOI 10.1016/S0891-5520(05)70329-9
   Chen JL, 2001, CLIN INFECT DIS, V33, P6, DOI 10.1086/320874
   Danino AM, 2004, PLAST RECONSTR SURG, V113, P2234, DOI 10.1097/01.PRS.0000123626.24313.31
   DeFranzo AJ, 2001, PLAST RECONSTR SURG, V108, P1184, DOI 10.1097/00006534-200110000-00013
   DESCAMPS V, 1994, LANCET, V344, P556, DOI 10.1016/S0140-6736(94)91956-9
   Elliott D, 2000, AM J SURG, V179, P361, DOI 10.1016/S0002-9610(00)00360-3
   File Thomas M. Jr., 2000, Comprehensive Therapy, V26, P73, DOI 10.1007/s12019-000-0015-8
   File TM, 1998, CLEV CLIN J MED, V65, P241, DOI 10.3949/ccjm.65.5.241
   FRANCIS KR, 1993, AM SURGEON, V59, P304
   GIBSON A, 1986, NEW ZEAL MED J, V99, P617
   Gilad J, 1998, SCAND J INFECT DIS, V30, P189, DOI 10.1080/003655498750003618
   Headley AJ, 2003, AM FAM PHYSICIAN, V68, P323
   JONES J, 1871, SURG MEMOIRS REBELLI
   Korhonen K, 2000, ANN CHIR GYNAECOL, V89, P7
   Leitch HA, 2000, CAN FAM PHYSICIAN, V46, P1460
   Lombardi C M, 2000, J Foot Ankle Surg, V39, P244
   Majeski J, 1997, SOUTHERN MED J, V90, P1065, DOI 10.1097/00007611-199711000-00001
   Mawhorter SD, 2000, CLEV CLIN J MED, V67, P21
   Miller J H, 1996, J Foot Ankle Surg, V35, P578
   Morykwas MJ, 1997, ANN PLAS SURG, V38, P553, DOI 10.1097/00000637-199706000-00001
   Mouës CM, 2004, WOUND REPAIR REGEN, V12, P11, DOI 10.1111/j.1067-1927.2004.12105.x
   Muqim Roohul, 2003, J Coll Physicians Surg Pak, V13, P711
   Norton KS, 2002, AM SURGEON, V68, P709
   RISEMAN JA, 1990, SURGERY, V108, P847
   Schmid MR, 1998, AM J ROENTGENOL, V170, P615, DOI 10.2214/ajr.170.3.9490940
   STAMENKOVIC I, 1984, NEW ENGL J MED, V310, P1689, DOI 10.1056/NEJM198406283102601
   Stevens DL, 1997, CLIN INFECT DIS, V25, pS160, DOI 10.1086/516249
   Stevens DL, 2002, CLIN INFECT DIS, V35, pS93, DOI 10.1086/341928
   Stevens DL, 2000, INT J MED MICROBIOL, V290, P497
   STEVENS DL, 1993, CLIN INFECT DIS, V16, pS195, DOI 10.1093/clinids/16.Supplement_4.S195
   Stone DR, 1997, DERMATOL CLIN, V15, P213, DOI 10.1016/S0733-8635(05)70430-7
   Tsai YH, 2004, J BONE JOINT SURG AM, V86A, P2497, DOI 10.2106/00004623-200411000-00021
   Verma SB, 2003, J EUR ACAD DERMATOL, V17, P591, DOI 10.1046/j.1468-3083.2003.00819.x
   Vincent J M, 2000, Adolesc Med, V11, P327
   Wall DB, 2000, AM J SURG, V179, P17, DOI 10.1016/S0002-9610(99)00259-7
   Wall DB, 2000, J AM COLL SURGEONS, V191, P227, DOI 10.1016/S1072-7515(00)00318-5
   WILSON B, 1952, Am Surg, V18, P416
   Wong CH, 2003, J BONE JOINT SURG AM, V85A, P1454, DOI 10.2106/00004623-200308000-00005
   Wong CH, 2004, EUR J CLIN MICROBIOL, V23, P909, DOI 10.1007/s10096-004-1237-y
   Wysoki MG, 1997, RADIOLOGY, V203, P859, DOI 10.1148/radiology.203.3.9169717
   Yen ZS, 2002, ACAD EMERG MED, V9, P1448, DOI 10.1111/j.1553-2712.2002.tb01619.x
   ZGONIS T, 2004, ORTHOKINETIC REV, V4, P20
NR 53
TC 0
Z9 1
U1 0
U2 1
PU AMER PODIATRIC MED ASSOC
PI BETHESDA
PA 9312 OLD GEORGETOWN ROAD, BETHESDA, MD 20814-1621 USA
SN 8750-7315
EI 1930-8264
J9 J AM PODIAT MED ASSN
JI J. Am. Podiatr. Med. Assoc.
PD JAN-FEB
PY 2006
VL 96
IS 1
BP 67
EP 72
DI 10.7547/0960067
PG 6
WC Orthopedics
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Orthopedics
GA 005OM
UT WOS:000234833700010
PM 16415286
DA 2026-07-24
ER

PT J
AU Lawall, H
AF Lawall, Holger
TI Treatment of chronic wounds
SO VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE
LA English
DT Review
DE Chronic wounds; local treatment; wound dressings; ulcer treatment
ID RANDOMIZED CONTROLLED-TRIAL; VENOUS LEG ULCERS; NEGATIVE-PRESSURE
   THERAPY; VACUUM-ASSISTED CLOSURE; DIABETIC FOOT ULCERS; QUALITY-OF-LIFE;
   VENUS III; MULTICENTER; ULTRASOUND; MANAGEMENT
AB Treatment of underlying diseases is of paramount importance due to the complex genesis of chronic wounds. This should be followed by a stage-adapted wound treatment, which usually consists of a phase-adapted wound debridement, ensued by a moist wound treatment. In case of epithelialization, a phase-specific shift to dry wound treatment should be performed. Despite the growing number of new wound dressings and therapeutics, current scientific data is incomplete, and evidence for the effectiveness of these wound dressings is only sparse. No significant advantage of one wound dressing over the other exists.
   The status of negative pressure treatment is still controversial, and no clear evidence is present. In order to achieve a permanent treatment success, causal therapy of venous obstructions and/or arterial disorders is of importance. Systematic and consistent compression therapy is of utmost significance when treating venous wounds.
C1 Asklepios W Klinikum Hamburg, Gefasszentrum, DE-22559 Hamburg, Germany.
RP Lawall, H (通讯作者)，Asklepios W Klinikum Hamburg, Gefasszentrum, Suurheid 20, DE-22559 Hamburg, Germany.
EM H.Lawall@asklepios.com
CR Al Ghazal P, 2011, WUND MANAGEMENT, V5, P254
   Al-Kurdi D, 2008, COCHRANE DB SYST REV
   Amsler F, 2009, J VASC SURG, V50, P668, DOI 10.1016/j.jvs.2009.05.018
   [Anonymous], VASA S75
   Armstrong DG, 2011, WOUND REPAIR REGEN, V19, P173, DOI 10.1111/j.1524-475X.2010.00658.x
   Armstrong DG, 2005, LANCET, V366, P1704, DOI 10.1016/S0140-6736(05)67695-7
   Aziz Z, 2010, COCHRANE DB SYST REV, V11
   Becker R, 2011, WUND MANAGEMENT, V1, P15
   Belcaro G, 2010, Panminerva Med, V52, P37
   Birke-Sorensen H, 2011, J PLAST RECONSTR AES, V64, pS1, DOI 10.1016/j.bjps.2011.06.001
   Blume PA, 2008, DIABETES CARE, V31, P631, DOI 10.2337/dc07-2196
   Bowling FL, 2011, J AM PODIAT MED ASSN, V101, P124, DOI 10.7547/1010124
   Carter JM, 2011, J PLAST SURG, V11, P38
   Carter MJ, 2010, J AM ACAD DERMATOL, V63, P668, DOI 10.1016/j.jaad.2009.09.007
   Cullum NA, 2010, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001180.pub3
   Deutsche Gesellschaft fur Phlebologie (DGP), DIAGNOSTIK UND THERA
   Dumville JC, 2009, HEALTH TECHNOL ASSES, V13, P1, DOI 10.3310/hta13550
   Dumville JC, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003091.pub2
   Dunn RM, 2011, J PLASTIC SURG, V11, P14
   Edwards JS, 2010, KNOWL MAN RES PRACT, V8, P1, DOI 10.1057/kmrp.2009.39
   Gin, 2008, NATIONALE VERS ORGUN, V60
   Goertz O, 2010, EUR SURG RES, V44, P23, DOI 10.1159/000260040
   Heinen MM, 2007, INT J NURS STUD, V44, P1296, DOI 10.1016/j.ijnurstu.2006.05.001
   Herberger K, 2011, VASA, V40, P131, DOI 10.1024/0301-1526/a000083
   Herberger K, 2011, DERMATOLOGY, V222, P244, DOI 10.1159/000326116
   Kahle B, 2011, DTSCH ARZTEBL INT, V108, P231, DOI 10.3238/arztebl.2011.0231
   Kavros Steven J, 2007, Adv Skin Wound Care, V20, P221, DOI 10.1097/01.ASW.0000266660.88900.38
   Kim BS, 2011, LIMB SALVAGE IN SEVE, V32, P32
   Lenselink E, 2011, J WOUND CARE, V20, P534, DOI 10.12968/jowc.2011.20.11.534
   Lipsky BA, 2006, PLAST RECONSTR SURG, V117, p212S, DOI 10.1097/01.prs.0000222737.09322.77
   Michaels JA, 2009, HEALTH TECHNOL ASSES, V13, P1, DOI 10.3310/hta13560
   Moffatt CJ, 2008, INT WOUND J, V5, P267, DOI 10.1111/j.1742-481X.2008.00487.x
   Moritz RK, 2011, WUND MANAGEMENT, V4, P185
   Mouës CM, 2011, AM J SURG, V201, P544, DOI 10.1016/j.amjsurg.2010.04.029
   Nelson EA, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001899.pub3
   OMeara S., 2010, COCHRANE DB SYST REV, pCD003557, DOI [10.1002/14651858.CD003557.pub3, DOI 10.1002/14651858.CD003557.PUB3]
   Partsch H, 2008, INT ANGIOL, V27, P193
   Peinemann F, 2011, DTSCH ARZTEBL INT, V108, P381, DOI 10.3238/arztebl.2011.0381
   Perez D, 2010, AM J SURG, V199, P14, DOI 10.1016/j.amjsurg.2008.12.029
   Piaggesi A, 1998, DIABETIC MED, V15, P412, DOI 10.1002/(SICI)1096-9136(199805)15:5<412::AID-DIA584>3.0.CO;2-1
   Purwins S, 2010, INT WOUND J, V7, P97, DOI 10.1111/j.1742-481X.2010.00660.x
   Rabe E, 2003, PHLEBOLOGIE, V32, P1
   Romanelli M, 2010, SKIN PHARMACOL PHYS, V23, P41, DOI 10.1159/000318266
   Ross RE, 2011, J WOUND CARE, V20, P490, DOI 10.12968/jowc.2011.20.10.490
   Sämann A, 2008, DIABETIC MED, V25, P557, DOI 10.1111/j.1464-5491.2008.02435.x
   Sepúlveda G, 2009, CIR ESPAN, V86, P171, DOI 10.1016/j.ciresp.2009.03.020
   Sibbald RG, 2011, ADV SKIN WOUND CARE, V24, P78, DOI 10.1097/01.ASW.0000394027.82702.16
   Steinsträsser L, 2008, CHIRURG, V79, P555, DOI 10.1007/s00104-008-1504-z
   Storm-Versloot Marja N, 2010, COCHRANE DATABASE SY, DOI 101002/14651858CD006.478
   Ubbink DT, 2008, BRIT J SURG, V95, P685, DOI 10.1002/bjs.6238
   González-Consuegra RV, 2011, J ADV NURS, V67, P926, DOI 10.1111/j.1365-2648.2010.05568.x
   Vuerstaek JDD, 2006, J VASC SURG, V44, P1029, DOI 10.1016/j.jvs.2006.07.030
   Watson JM, 2011, HEALTH TECHNOL ASSES, V15, P1, DOI 10.3310/hta15130
   Watson JM, 2011, BMJ-BRIT MED J, V342, DOI 10.1136/bmj.d1092
   Wilm S, 2005, VASOMED, V17, P143
   Wozniak G, 2011, GEFASSCHIRURGIE, V16, P281, DOI 10.1007/s00772-011-0884-4
NR 56
TC 11
Z9 13
U1 0
U2 63
PU VERLAG HANS HUBER HOGREFE AG
PI BERN 9
PA LAENGGASS-STRASSE 76, CH-3000 BERN 9, SWITZERLAND
SN 0301-1526
J9 VASA
JI Vasa
PD NOV
PY 2012
VL 41
IS 6
BP 396
EP 409
DI 10.1024/0301-1526/a000230
PG 14
WC Peripheral Vascular Disease
WE Science Citation Index Expanded (SCI-EXPANDED)
SC Cardiovascular System & Cardiology
GA 036ZW
UT WOS:000311071800003
PM 23129035
DA 2026-07-24
ER

EF