Independent screening workflow

Screening unit:
4,797 unique Article/Review-type records remaining after document-type,
retraction, and duplicate/version processing.

Review process:
Two trained researchers independently evaluated each record using the title,
abstract, author keywords, and Keywords Plus. Each researcher recorded an
independent Included/Excluded decision and a record-level rationale before
reconciliation.

Initial agreement:
4,782 records.

Initial disagreement:
15 records.
- Reviewer 1 Included / Reviewer 2 Excluded: 4 records.
- Reviewer 1 Excluded / Reviewer 2 Included: 11 records.

Resolution:
All 15 disagreements were resolved through discussion and, when necessary,
adjudication by a third researcher. The final decision was Excluded for all
15 records, and no disagreement remained unresolved.

Final relevance decisions:
- Included: 4,063 records.
- Excluded as not topically relevant: 734 records.

Record-level reviewer decisions, rationales, disagreement indicators, final
decisions, and final rationales are provided in Supplemental File 2.
