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Chapter 5

Acides et bases

Chapter 5

Acids and Bases

Brønsted-Lowry Acids and Bases
In 1923, the Brønsted–Lowry definition of acids and bases was proposed by Johannes Brønsted and Thomas Lowry. According to this theory, a …
Lewis Acids and Bases
This lesson delves into Lewis acids and bases in the context of the octet rule for electron-deficient compounds. Here, the concept is discussed, …
Acid and Bases: Ka, pKa, and Relative Strengths
This lesson delves into a critical aspect of the relative strengths of acids and bases. The strength of an acid is evaluated by the acid dissociation into …
Position of Equilibrium in Acid-Base Reactions
In any solution, the value of pKa indicates whether an acid is completely dissociated or not. A negative pKa corresponds to a stronger acid, whereas a …
Molecular Structure and Acidity
An acid can be deprotonated to form a conjugate base or an anion. If the produced anion is more stable, then the acid is stronger. On the contrary, if the …
Leveling Effect and Non-Aqueous Acid-Base Solutions
This lesson defines the leveling effect in acidic and basic solutions and its role in aqueous and non-aqueous solutions. It is essential to understand the …
Solvating Effects
An understanding of the solvating effect helps rationalize the relation between solvation and acidity of the compound. In addition, this also explains the …
Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
The direct functionalization of C-H bonds is an important and long standing goal in organic chemistry. Such transformations can be very powerful in order …
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
This protocol presents the use of Lewis acidic multi-role reagents to circumvent kinetic trapping observed during the self-assembly of information-encoded …
Characterizing Lewis Pairs Using Titration Coupled with In Situ Infrared Spectroscopy
Lewis acid-activation of carbonyl-containing substrates is a fundamental basis for facilitating transformations in organic chemistry. Historically, …