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Chapter 15

Pharmacotherapy of Depression and Anxiety Disorders

Chapter 15

Pharmacotherapy of Depression and Anxiety Disorders

Depression: Overview
Depression is a common mental illness that manifests as major depression, persistent depressive disorder, and bipolar I and II disorders. It can be …
Antidepressant Drugs: Overview
Antidepressant drugs alleviate symptoms of depression by enhancing neurotransmission in the brain. These agents are classified based on their chemical …
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
Tricyclic antidepressants, or TCAs, are first-generation antidepressants. They block serotonin and norepinephrine reuptake transporters while inhibiting …
Antidepressant Drugs: MAOIs and Other Agents
Monoamine oxidase inhibitors, or MAOIs, inhibit monoamine oxidase, increasing neurotransmitter levels. Atypical antidepressants encompass drugs with …
Parkinson’s Disease: Overview
Neurodegenerative disorders are progressive conditions characterized by the irreversible loss of neurons in specific brain regions. The primary …
Parkinson’s Disease: Treatment
Parkinson's Disease or PD is a neurodegenerative disorder characterized by an imbalance between cholinergic and reduced dopaminergic neurons. The …
Alzheimer’s Disease: Overview
Alzheimer's disease, or AD, is a neurodegenerative disorder primarily affecting older adults, causing impaired memory and cognitive decline through …
Alzheimer’s Disease: Treatment
The goal of Alzheimer's disease or AD pharmacotherapy is to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms, …
Reinstatement of Drug-seeking in Mice Using the Conditioned Place Preference Paradigm
The present protocol describes the Conditioned Place Preference (CPP) as a model of relapse in drug addiction. In this model, animals are first trained to …
Evaluating the Anti-depression Effect of Xiaoyaosan on Chronically-stressed Mice
In addition to the standardized use of antidepressant medications and psychotherapy, the usage of traditional Chinese medicine has lead to an overall …
High-Throughput Small Molecule Drug Screening For Age-Related Sleep Disorders Using Drosophila melanogaster
Sleep, an essential component of health and overall well-being, often presents challenges for older individuals who frequently experience sleep disorders …