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Chapter 16

Anxiolytics, Sedatives and Hypnotics

Chapter 16

Anxiolytics, Sedatives and Hypnotics

Anxiety: Overview
Anxiety, a mental disorder characterized by excessive worry, fear, and apprehension, significantly affects daily life. Common symptoms include sweating, …
Anxiolytic Drugs: Overview
Anxiolytic drugs effectively manage anxiety disorders by alleviating symptoms like excessive fear, tachycardia, and tremors. Anxiolytics encompass …
Anxiolytic Drugs: Benzodiazepines and Buspirone
Benzodiazepines are anxiolytic drugs known for their safety due to a substantial therapeutic-to-lethal dose ratio. After oral administration, these …
Sedatives and Hypnotics: Overview
Sedatives belong to a class of drugs that calms the individual, while hypnotics induce and maintain sleep. Both categories work by slowing down the brain …
Management of Insomnia
The sleep cycle comprises multiple stages, progressing from wakefulness to light sleep and finally into deep sleep, concluding with the Rapid Eye Movement …
Sedatives and Hypnotics Drugs: Barbiturates
Sedatives and hypnotics are drugs that reduce anxiety, induce calmness, or promote sleep by suppressing the CNS. Barbiturates, a class of …
Sedatives and Hypnotics Drugs: Benzodiazepines
Benzodiazepines are a class of sedative and hypnotic drugs that vary in chemical structure and pharmacokinetic properties. These drugs enhance GABA's …
Sedatives and Hypnotics Drugs: Miscellaneous Agents
A variety of  CNS depressants are utilized as sedatives and hypnotics, each with distinct properties. Melatonin congeners help treat insomnia and jet …
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
This manuscript presents a step-by-step protocol for screening compounds at gamma-aminobutyric acid type A (GABAA) receptors and its use towards the …
Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements
The overall goal of this study is to describe the methodology of the elevated plus maze (EPM) test in combination with a video tracking software. The …
High-Throughput Method for Measuring Alcohol Sedation Time of Individual Drosophila melanogaster
Drosophila melanogaster provides an excellent model to study the genetic underpinnings of alcohol sensitivity. In contrast to studies in human …