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Chapter 19

Lower Respiratory Disorders

Chapter 19

Lower Respiratory Disorders

Asthma: Pathogenesis and Management
Asthma, a chronic respiratory condition, entails airway inflammation, hyper-reactivity, and reversible obstruction of the airways. It is categorized as …
Antiasthma Drugs: β2-Adrenoceptor Agonists
Bronchodilators play a pivotal role in asthma management. They ease airway constriction by relaxing bronchial muscles. One class of bronchodilators …
Antiasthma Drugs: Methylxanthines
Methylxanthines, such as theophylline, act as bronchodilators to manage asthma. Theophylline's exact mechanism of action is complex, potentially …
Antiasthma Drugs: Leukotriene Modifiers
Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, effectively manage chronic asthma by targeting inflammatory mediators produced …
Antiasthma Drugs:  Muscarinic Receptor Antagonists
Muscarinic receptor antagonists, or antimuscarinic agents, are a class of bronchodilators used for asthma treatment. They inhibit the action of …
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
Inhaled corticosteroids, or ICS, are potent anti-inflammatory drugs pivotal in asthma management. They precisely target the bronchial mucosa to control …
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Anti-inflammatory drugs such as mast cell stabilizers and anti-IgE drugs play a crucial role in asthma management. Mast cell stabilizers, such as …
COPD: Pathogenesis and Clinical Features
COPD, short for chronic obstructive pulmonary disease, is a progressive lung disease that primarily affects the airways, leading to the gradual loss of …
COPD: Management Using Bronchodilators and Corticosteroids
Chronic obstructive pulmonary disease, or COPD, encompasses progressive lung conditions, including chronic bronchitis, emphysema, and asthma. Its symptoms …
Murine Model of Allergen Induced Asthma
Asthma is a major cause of morbidity and mortality, affecting some 300 million people throughout the world.1 More than 8% of the US population has asthma, …
Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
Pneumonia, the inflammatory state of lung tissue primarily due to microbial infection, claimed 52,306 lives in the United States in 20071 and resulted in …
The WinCF Model – An Inexpensive and Tractable Microcosm of a Mucus Plugged Bronchiole to Study the Microbiology of Lung Infections
Many chronic airway diseases result in mucus plugging of the airways. Lungs of an individual with cystic fibrosis are an exemplary case where their …