< Back to Core

Chapter 24

Drugs for Nausea and Vomiting

Chapter 24

Drugs for Nausea and Vomiting

Pathophysiology of Vomiting
Vomiting, or emesis, is a protective reflex that forcefully expels stomach content due to triggers like medication, pregnancy, GI disorders or infections, …
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
Vomiting is a common side effect among individuals undergoing chemo and radiation therapy. In these patients, the damaged GI mucosa releases serotonin, …
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
The central vomiting center and the chemoreceptor trigger zone in the brainstem are rich in neurokinin 1 or NK1 receptors. During chemotherapy, the GI …
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
Vomiting is a distressing symptom often triggered by cancer chemotherapy. Dopamine receptor antagonists are key antiemetics. They bind to dopamine …
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Vomiting, a protective reflex to expel toxins from the gut, can become a distressing side effect of regular chemotherapy. Neurons near the chemoreceptor …
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
The available routes of administration commonly used for medications and fluids in the acute care setting are generally limited to oral, intravenous, or …
Assessing the Autonomic and Behavioral Effects of Passive Motion in Rats using Elevator Vertical Motion and Ferris-Wheel Rotation
The overall goal of this study is to assess the autonomic and behavioral effects of passive motion in rodents using the elevator vertical motion and …
Ear Plaster Therapy as a Safe and Effective Treatment for Gestational Vomiting
Nausea and vomiting in pregnancy (NVP) are common symptoms that often complicate early pregnancy for many women. While clinical treatments such as …