Lesley Ann Sutton

Department of Immunology, Uppsala University

Affiliated withUppsala University Karolinska Institutet

Research Area

Cancer Research

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 14	2018

Other Publications

Article	Year
Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen. Blood\| PubMed ID: 19713457	2009
IGHV3-21 gene frequency in a Swedish cohort of patients with newly diagnosed chronic lymphocytic leukemia. Clinical lymphoma, myeloma & leukemia\| PubMed ID: 22464020	2012
Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia. American journal of hematology\| PubMed ID: 22674506	2012
Temporal dynamics of clonal evolution in chronic lymphocytic leukemia with stereotyped IGHV4-34/IGKV2-30 antigen receptors: longitudinal immunogenetic evidence. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 23922244	2013
Antigen selection in B-cell lymphomas--tracing the evidence. Seminars in cancer biology\| PubMed ID: 23932942	2013
A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma. Epigenetics\| PubMed ID: 24107828	2013
In situ Protein Detection for Companion Diagnostics. Frontiers in oncology\| PubMed ID: 24199171	2013
IgG-switched CLL has a distinct immunogenetic signature from the common MD variant: ontogenetic implications. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24240110	2014
Lymphoma development in patients with autoimmune and inflammatory disorders--what are the driving forces? Seminars in cancer biology\| PubMed ID: 24333759	2014
Immunogenetic studies of chronic lymphocytic leukemia: revelations and speculations about ontogeny and clinical evolution. Cancer research\| PubMed ID: 25074616	2014
Clonal evolution in chronic lymphocytic leukemia: impact of subclonality on disease progression. Expert review of hematology\| PubMed ID: 25345442	2015
Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting. Haematologica\| PubMed ID: 25480502	2015
An entity evolving into a community: defining the common ancestor and evolutionary trajectory of chronic lymphocytic leukemia stereotyped subset #4. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 25486132	2015
Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution. Haematologica\| PubMed ID: 25552678	2015
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations. Blood\| PubMed ID: 25634617	2015
Molecular evidence for antigen drive in the natural history of mantle cell lymphoma. The American journal of pathology\| PubMed ID: 25843681	2015
The complex interplay between cell-intrinsic and cell-extrinsic factors driving the evolution of chronic lymphocytic leukemia. Seminars in cancer biology\| PubMed ID: 25963298	2015
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia. The Journal of experimental medicine\| PubMed ID: 25987724	2015
ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy. Bioinformatics (Oxford, England)\| PubMed ID: 26249808	2015
Prognostic relevance of MYD88 mutations in CLL: the jury is still out. Blood\| PubMed ID: 26294719	2015
Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 26338994	2016
UGT2B17 expression: a novel prognostic marker within IGHV-mutated chronic lymphocytic leukemia? Haematologica\| PubMed ID: 26589911	2016
An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 26647217	2016
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations. Blood\| PubMed ID: 26675346	2016
Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go? Haematologica\| PubMed ID: 26928246	2016
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study. The Lancet. Haematology\| PubMed ID: 27030157	2014
Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference. Haematologica\| PubMed ID: 27102498	2016
Not all subclones matter in CLL. Blood\| PubMed ID: 27127300	2016
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia. Oncotarget\| PubMed ID: 27191993	2016
Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors. Haematologica\| PubMed ID: 27198719	2016
ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres. Haematologica\| PubMed ID: 27479817	2016
Massive and parallel expression profiling using microarrayed single-cell sequencing. Nature communications\| PubMed ID: 27739429	2016
Numerous Ontogenetic Roads to Mantle Cell Lymphoma: Immunogenetic and Immunohistochemical Evidence. The American journal of pathology\| PubMed ID: 28457696	2017
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 28536306	2017
Immunoglobulin genes in chronic lymphocytic leukemia: key to understanding the disease and improving risk stratification. Haematologica\| PubMed ID: 28566340	2017
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy. Haematologica\| PubMed ID: 29269523	2018
Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations. Haematologica\| PubMed ID: 29449433	2018
Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia. Haematologica\| PubMed ID: 30262567	2018
Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia. BMC bioinformatics\| PubMed ID: 30453883	2018