Sichuan Institute for Brain Science and Brain-inspired Intelligence 1 article published in JoVE Developmental Biology Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex Ke Chen*1,2, Yilei Zhao*1, Ting Liu1, Zhaohao Su1, Huiliang Yu1, Leanne Lai Hang Chan3,4, Tiejun Liu1,2, Dezhong Yao1,2 1The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for NeuroInformation, University of Electronic Science and Technology of China, 2Sichuan Institute for Brain Science and Brain-inspired Intelligence, 3Department of Electronic Engineering, City University of Hong Kong, 4Centre for Biosystems, Neuroscience, and Nanotechnology, City University of Hong Kong Here, we present detailed protocols for monocular visual deprivation and ocular dominance plasticity analysis, which are important methods for studying the neural mechanisms of visual plasticity during the critical period and the effects of specific genes on visual development.
