Universitas Airlangga 1 article published in JoVE Bioengineering In vitro Induction of Human Dental Pulp Stem Cells Toward Pancreatic Lineages Suryo Kuncorojakti*1,2, Watchareewan Rodprasert*1, Quynh Dang Le1,5, Thanaphum Osathanon3,4, Prasit Pavasant3,4, Chenphop Sawangmake1,5,6 1Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Veterinary Pharmacology and Stem Cell Research Laboratory, Faculty of Veterinary Science, Chulalongkorn University, 2Department of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, 3Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, 4Center of Excellence in Regenerative Dentistry, Faculty of Dentistry, Chulalongkorn University, 5Veterinary Stem Cell and Bioengineering Research Unit, Faculty of Veterinary Science, Chulalongkorn University, 6Department of Pharmacology, Faculty of Veterinary Science, Chulalongkorn University This protocol presents a comparison between two different induction protocols for differentiating human dental pulp stem cells (hDPSCs) toward pancreatic lineages in vitro: the integrative protocol and the non-integrative protocol. The integrative protocol generates more insulin producing cells (IPCs).