University of Delhi 1 article published in JoVE Medicine Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds Marc E. Bracke1, Bart I. Roman2, Christian V. Stevens2, Liselot M. Mus1, Virinder S. Parmar3, Olivier De Wever1, Marc M. Mareel1 1Department of Radiation Oncology and Experimental Cancer Research, University of Ghent, 2Department of Sustainable Organic Chemistry and Technology, University of Ghent, 3Department of Chemistry, University of Delhi Here, we present a protocol to study the invasion of tumor cells into living normal tissue fragments in three dimensions. This organ culture technique is mainly applied to test potentially anti-invasive drugs in vitro.
