Ming Chi University of Technology 1 article published in JoVE Bioengineering Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release Chih-Yu Kuo1, Ting-Yu Liu2, Kuan-Syun Wang2, Andri Hardiansyah3, Yen-Ting Lin4, Hsueh-Yung Chen4, Wen-Yen Chiu1,4,5 1Institute of Polymer Science and Engineering, National Taiwan University, 2Department of Materials Engineering, Ming Chi University of Technology, 3Department of Metallurgy and Materials Engineering, Bandung Institute of Technology and Science, 4Department of Chemical Engineering, National Taiwan University, 5Department of Materials Science and Engineering, National Taiwan University This manuscript describes the preparation of magnetic and thermal-sensitive microgels via a temperature-induced emulsion without chemical reaction. These sensitive microgels were synthesized by mixing poly(N-isopropylacrylamide) (PNIPAAm), polyethylenimine (PEI) and Fe3O4-NH2 nanoparticles for the potential use in magnetically and thermally triggered drug-release.
