West China Hospital of Sichuan University

1 article published in JoVE

• Bioengineering

  
  Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes Meihua Wan^1,2, Pouya Amrollahi^2,3, Dali Sun⁴, Christopher Lyon^2,3, Tony Y. Hu^{2,3 1}Department of Integrated Traditional Chinese and Western Medicine, West China Hospital of Sichuan University, ²Virginia G. Piper Biodesign Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, ³School of Biological and Health Systems Engineering, Arizona State University, ⁴Department of Electrical and Computer Engineering, North Dakota State University Clinical translation of exosome-derived biomarkers for diseased and malignant cells is hindered by the lack of rapid and accurate quantification methods. This report describes the use of low-magnification dark-field microscope images to quantify specific exosome subtypes in small volume serum or plasma samples.