West China Hospital of Sichuan University 5 articles published in JoVE Neuroscience Manual Segmentation of the Human Choroid Plexus Using Brain MRI Deepthi Bannai*1,2, Yuan Cao*3,4, Matcheri Keshavan1,2, Martin Reuter5,6,7, Paulo Lizano1,2,8 1Department of Psychiatry, Beth Israel Deaconess Medical Center, 2Division of Translational Neuroscience, Beth Israel Deaconess Medical Center, 3Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, 4Department of Psychiatry and Psychotherapy, Jena University Hospital, 5AI in Medical Imaging, German Center for Neurodegenerative Diseases (DZNE), 6A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 7Department of Radiology, Harvard Medical School, 8Department of Psychiatry, Harvard Medical School Despite the crucial role of the choroid plexus in the brain, neuroimaging studies of this structure are scarce due to the lack of reliable automated segmentation tools. The present protocol aims to ensure gold-standard manual segmentation of the choroid plexus that can inform future neuroimaging studies. Medicine Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy Zhujuan Wu*1, Ye Tian*2, Ziwei Chen1, Anping Su2 1West China School of Medicine, Sichuan University, 2Sichuan University West China Hospital Here, we present a protocol to describe the methodology for the transoral endoscopic thyroidectomy vestibular approach in detail. Medicine A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images Ye Tian1, Jingqiang Zhu2, Lei Zhang3, Lichao Mou3, Xiaoxiang Zhu3, Yilei Shi3, Buyun Ma1, Wanjun Zhao2 1Department of Ultrasonography, West China Hospital of Sichuan University, 2Department of Thyroid Surgery, West China Hospital of Sichuan University, 3MedAI Technology (Wuxi) Co. Ltd. Here, a new model for thyroid nodule detection in ultrasound images is proposed, which uses Swin Transformer as the backbone to perform long-range context modeling. Experiments prove that it performs well in terms of sensitivity and accuracy. Immunology and Infection Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model Yuanfan Qian1,2, Linye He1,2, Anping Su1,2, Yiguo Hu3, Jingqiang Zhu1 1Thyroid and Parathyroid Surgery Center, West China Hospital of Sichuan University, 2The Laboratory of Thyroid and Parathyroid Disease, West China Hospital of Sichuan University, 3State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center Several types of animal models of Hashimoto's thyroiditis have been established, as has spontaneous autoimmune thyroiditis in the NOD mouse. H-2h4 mice are a simple and reliable model for HT induction. This article describes this approach and evaluates the pathological process for a better understanding of the SAT murine model. Bioengineering Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes Meihua Wan1,2, Pouya Amrollahi2,3, Dali Sun4, Christopher Lyon2,3, Tony Y. Hu2,3 1Department of Integrated Traditional Chinese and Western Medicine, West China Hospital of Sichuan University, 2Virginia G. Piper Biodesign Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, 3School of Biological and Health Systems Engineering, Arizona State University, 4Department of Electrical and Computer Engineering, North Dakota State University Clinical translation of exosome-derived biomarkers for diseased and malignant cells is hindered by the lack of rapid and accurate quantification methods. This report describes the use of low-magnification dark-field microscope images to quantify specific exosome subtypes in small volume serum or plasma samples.
