1 article published in JoVE

• Medicine

  
  An In Vitro System to Study Tumor Dormancy and the Switch to Metastatic Growth Dalit Barkan¹, Jeffrey E. Green^{2 1}Department of Biology, University of Haifa, ²Transgenic Oncogenesis and Genomics Section, Laboratory of Cancer Biology and Genetics, National Cancer Institute A modified 3-D in vitro system is presented in which growth characteristics of several tumor cell lines in reconstituted basement membrane correlate with the dormant or proliferative behavior of the tumor cells at a metastatic secondary site in vivo.