Kure Medical Cancer Center 1 article published in JoVE Cancer Research Generation of a Liver Orthotopic Human Uveal Melanoma Xenograft Platform in Immunodeficient Mice Ken Kageyama1,3, Shinji Ozaki2,3, Takami Sato3 1Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, 2Department of Surgery, National Hospital Organization, Kure Medical Cancer Center, 3Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University Orthotopic human liver metastatic uveal melanoma xenograft mouse models were created using surgical orthotopic implantation techniques with patient-derived tumor chunk and needle injection techniques with cultured human uveal melanoma cell lines.
